---
OA_type: closed access
_id: '21819'
abstract:
- lang: eng
  text: The ability of molecular photoswitches to convert on/off responses into large
    macroscale property change is fundamental to light-responsive materials. However,
    moving beyond simple binary responses necessitates the introduction of new elements
    that control the chemistry of the photoswitching process at the molecular scale.
    To achieve this goal, we designed, synthesized and developed a single photochrome,
    based on a modified donor–acceptor Stenhouse adduct (DASA), capable of independently
    addressing multiple molecular states. The multi-stage photoswitch enables complex
    switching phenomena. To demonstrate this, we show spatial control of the transformation
    of a three-stage photoswitch by tuning the population of intermediates along the
    multi-step reaction pathway of the DASAs without interfering with either the first
    or final stage. This allows for a photonic three-stage logic gate where the secondary
    wavelength solely negates the input of the primary wavelength. These results provide
    a new strategy to move beyond traditional on/off binary photochromic systems and
    enable the design of future molecular logic systems.
article_processing_charge: No
article_type: original
author:
- first_name: Friedrich J
  full_name: Stricker, Friedrich J
  id: 7aca2cfc-46cf-11f0-abd3-8c96b5186745
  last_name: Stricker
- first_name: David M.
  full_name: Sanchez, David M.
  last_name: Sanchez
- first_name: Umberto
  full_name: Raucci, Umberto
  last_name: Raucci
- first_name: Neil D.
  full_name: Dolinski, Neil D.
  last_name: Dolinski
- first_name: Manuel S.
  full_name: Zayas, Manuel S.
  last_name: Zayas
- first_name: Jan
  full_name: Meisner, Jan
  last_name: Meisner
- first_name: Craig. J.
  full_name: Hawker, Craig. J.
  last_name: Hawker
- first_name: Todd. J.
  full_name: Martínez, Todd. J.
  last_name: Martínez
- first_name: Javier
  full_name: Read de Alaniz, Javier
  last_name: Read de Alaniz
citation:
  ama: Stricker FJ, Sanchez DM, Raucci U, et al. A multi-stage single photochrome
    system for controlled photoswitching responses. <i>Nature Chemistry</i>. 2022;14:942-948.
    doi:<a href="https://doi.org/10.1038/s41557-022-00947-8">10.1038/s41557-022-00947-8</a>
  apa: Stricker, F. J., Sanchez, D. M., Raucci, U., Dolinski, N. D., Zayas, M. S.,
    Meisner, J., … Read de Alaniz, J. (2022). A multi-stage single photochrome system
    for controlled photoswitching responses. <i>Nature Chemistry</i>. Springer Nature.
    <a href="https://doi.org/10.1038/s41557-022-00947-8">https://doi.org/10.1038/s41557-022-00947-8</a>
  chicago: Stricker, Friedrich J, David M. Sanchez, Umberto Raucci, Neil D. Dolinski,
    Manuel S. Zayas, Jan Meisner, Craig. J. Hawker, Todd. J. Martínez, and Javier
    Read de Alaniz. “A Multi-Stage Single Photochrome System for Controlled Photoswitching
    Responses.” <i>Nature Chemistry</i>. Springer Nature, 2022. <a href="https://doi.org/10.1038/s41557-022-00947-8">https://doi.org/10.1038/s41557-022-00947-8</a>.
  ieee: F. J. Stricker <i>et al.</i>, “A multi-stage single photochrome system for
    controlled photoswitching responses,” <i>Nature Chemistry</i>, vol. 14. Springer
    Nature, pp. 942–948, 2022.
  ista: Stricker FJ, Sanchez DM, Raucci U, Dolinski ND, Zayas MS, Meisner J, Hawker
    CJ, Martínez TJ, Read de Alaniz J. 2022. A multi-stage single photochrome system
    for controlled photoswitching responses. Nature Chemistry. 14, 942–948.
  mla: Stricker, Friedrich J., et al. “A Multi-Stage Single Photochrome System for
    Controlled Photoswitching Responses.” <i>Nature Chemistry</i>, vol. 14, Springer
    Nature, 2022, pp. 942–48, doi:<a href="https://doi.org/10.1038/s41557-022-00947-8">10.1038/s41557-022-00947-8</a>.
  short: F.J. Stricker, D.M. Sanchez, U. Raucci, N.D. Dolinski, M.S. Zayas, J. Meisner,
    C.J. Hawker, T.J. Martínez, J. Read de Alaniz, Nature Chemistry 14 (2022) 942–948.
date_created: 2026-05-06T10:56:14Z
date_published: 2022-06-09T00:00:00Z
date_updated: 2026-05-18T09:13:44Z
day: '09'
ddc:
- '540'
doi: 10.1038/s41557-022-00947-8
extern: '1'
external_id:
  pmid:
  - '35681046'
intvolume: '        14'
language:
- iso: eng
month: '06'
oa_version: None
page: 942-948
pmid: 1
publication: Nature Chemistry
publication_identifier:
  eissn:
  - 1755-4349
  issn:
  - 1755-4330
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: A multi-stage single photochrome system for controlled photoswitching responses
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 14
year: '2022'
...
---
OA_type: green
_id: '21823'
abstract:
- lang: eng
  text: DFT calculations were used to find an optimal substitution site on the triene
    backbone of a donor–acceptor Stenhouse adduct photoswitch to tune the equillibrium
    and switching kinetics of DASA without modifying the donor and acceptor groups.
    Using this approach we demonstrate a new means to tuning DASA based photoswitches
    by increasing the energy of the closed form relative to the open form. To highlight
    the potential of this approach a new DASA derivative bearing a methyl substituent
    on the 5-position of the triene was synthesized and the effect of this substitution
    was studied using 1H NMR spectroscopy, time-dependent UV-Vis and solvatochromic
    analysis. The new DASA derivative shows a higher dark equillibrium, favoring the
    open form, and drastically faster thermal recovery than the unsubstituted derivative
    with the same donor and acceptor.
article_processing_charge: No
article_type: original
author:
- first_name: Julie A.
  full_name: Peterson, Julie A.
  last_name: Peterson
- first_name: Friedrich J
  full_name: Stricker, Friedrich J
  id: 7aca2cfc-46cf-11f0-abd3-8c96b5186745
  last_name: Stricker
- first_name: Javier
  full_name: Read de Alaniz, Javier
  last_name: Read de Alaniz
citation:
  ama: Peterson JA, Stricker FJ, Read de Alaniz J. Improving the kinetics and dark
    equilibrium of donor-acceptor Stenhouse adduct by triene backbone design. <i>Chemical
    Communications</i>. 2022;58(14):2303-2306. doi:<a href="https://doi.org/10.1039/d1cc06235b">10.1039/d1cc06235b</a>
  apa: Peterson, J. A., Stricker, F. J., &#38; Read de Alaniz, J. (2022). Improving
    the kinetics and dark equilibrium of donor-acceptor Stenhouse adduct by triene
    backbone design. <i>Chemical Communications</i>. Royal Society of Chemistry. <a
    href="https://doi.org/10.1039/d1cc06235b">https://doi.org/10.1039/d1cc06235b</a>
  chicago: Peterson, Julie A., Friedrich J Stricker, and Javier Read de Alaniz. “Improving
    the Kinetics and Dark Equilibrium of Donor-Acceptor Stenhouse Adduct by Triene
    Backbone Design.” <i>Chemical Communications</i>. Royal Society of Chemistry,
    2022. <a href="https://doi.org/10.1039/d1cc06235b">https://doi.org/10.1039/d1cc06235b</a>.
  ieee: J. A. Peterson, F. J. Stricker, and J. Read de Alaniz, “Improving the kinetics
    and dark equilibrium of donor-acceptor Stenhouse adduct by triene backbone design,”
    <i>Chemical Communications</i>, vol. 58, no. 14. Royal Society of Chemistry, pp.
    2303–2306, 2022.
  ista: Peterson JA, Stricker FJ, Read de Alaniz J. 2022. Improving the kinetics and
    dark equilibrium of donor-acceptor Stenhouse adduct by triene backbone design.
    Chemical Communications. 58(14), 2303–2306.
  mla: Peterson, Julie A., et al. “Improving the Kinetics and Dark Equilibrium of
    Donor-Acceptor Stenhouse Adduct by Triene Backbone Design.” <i>Chemical Communications</i>,
    vol. 58, no. 14, Royal Society of Chemistry, 2022, pp. 2303–06, doi:<a href="https://doi.org/10.1039/d1cc06235b">10.1039/d1cc06235b</a>.
  short: J.A. Peterson, F.J. Stricker, J. Read de Alaniz, Chemical Communications
    58 (2022) 2303–2306.
date_created: 2026-05-06T10:59:03Z
date_published: 2022-01-17T00:00:00Z
date_updated: 2026-05-18T09:46:30Z
day: '17'
ddc:
- '540'
doi: 10.1039/d1cc06235b
extern: '1'
external_id:
  pmid:
  - '35075464'
intvolume: '        58'
issue: '14'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1039/D1CC06235B
month: '01'
oa: 1
oa_version: Accepted Version
page: 2303-2306
pmid: 1
publication: Chemical Communications
publication_identifier:
  eissn:
  - 1364-548X
  issn:
  - 1359-7345
publication_status: published
publisher: Royal Society of Chemistry
quality_controlled: '1'
scopus_import: '1'
status: public
title: Improving the kinetics and dark equilibrium of donor-acceptor Stenhouse adduct
  by triene backbone design
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 58
year: '2022'
...
---
_id: '14520'
abstract:
- lang: eng
  text: 'This dataset comprises all data shown in the figures of the submitted article
    "Compact vacuum gap transmon qubits: Selective and sensitive probes for superconductor
    surface losses" at arxiv.org/abs/2206.14104. Additional raw data are available
    from the corresponding author on reasonable request.'
article_processing_charge: No
author:
- first_name: Martin
  full_name: Zemlicka, Martin
  id: 2DCF8DE6-F248-11E8-B48F-1D18A9856A87
  last_name: Zemlicka
  orcid: 0009-0005-0878-3032
- first_name: Elena
  full_name: Redchenko, Elena
  id: 2C21D6E8-F248-11E8-B48F-1D18A9856A87
  last_name: Redchenko
- first_name: Matilda
  full_name: Peruzzo, Matilda
  id: 3F920B30-F248-11E8-B48F-1D18A9856A87
  last_name: Peruzzo
  orcid: 0000-0002-3415-4628
- first_name: Farid
  full_name: Hassani, Farid
  id: 2AED110C-F248-11E8-B48F-1D18A9856A87
  last_name: Hassani
  orcid: 0000-0001-6937-5773
- first_name: Andrea
  full_name: Trioni, Andrea
  id: 42F71B44-F248-11E8-B48F-1D18A9856A87
  last_name: Trioni
- first_name: Shabir
  full_name: Barzanjeh, Shabir
  id: 2D25E1F6-F248-11E8-B48F-1D18A9856A87
  last_name: Barzanjeh
  orcid: 0000-0003-0415-1423
- first_name: Johannes M
  full_name: Fink, Johannes M
  id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
  last_name: Fink
  orcid: 0000-0001-8112-028X
citation:
  ama: 'Zemlicka M, Redchenko E, Peruzzo M, et al. Compact vacuum gap transmon qubits:
    Selective and sensitive probes for superconductor surface losses. 2022. doi:<a
    href="https://doi.org/10.5281/ZENODO.8408897">10.5281/ZENODO.8408897</a>'
  apa: 'Zemlicka, M., Redchenko, E., Peruzzo, M., Hassani, F., Trioni, A., Barzanjeh,
    S., &#38; Fink, J. M. (2022). Compact vacuum gap transmon qubits: Selective and
    sensitive probes for superconductor surface losses. Zenodo. <a href="https://doi.org/10.5281/ZENODO.8408897">https://doi.org/10.5281/ZENODO.8408897</a>'
  chicago: 'Zemlicka, Martin, Elena Redchenko, Matilda Peruzzo, Farid Hassani, Andrea
    Trioni, Shabir Barzanjeh, and Johannes M Fink. “Compact Vacuum Gap Transmon Qubits:
    Selective and Sensitive Probes for Superconductor Surface Losses.” Zenodo, 2022.
    <a href="https://doi.org/10.5281/ZENODO.8408897">https://doi.org/10.5281/ZENODO.8408897</a>.'
  ieee: 'M. Zemlicka <i>et al.</i>, “Compact vacuum gap transmon qubits: Selective
    and sensitive probes for superconductor surface losses.” Zenodo, 2022.'
  ista: 'Zemlicka M, Redchenko E, Peruzzo M, Hassani F, Trioni A, Barzanjeh S, Fink
    JM. 2022. Compact vacuum gap transmon qubits: Selective and sensitive probes for
    superconductor surface losses, Zenodo, <a href="https://doi.org/10.5281/ZENODO.8408897">10.5281/ZENODO.8408897</a>.'
  mla: 'Zemlicka, Martin, et al. <i>Compact Vacuum Gap Transmon Qubits: Selective
    and Sensitive Probes for Superconductor Surface Losses</i>. Zenodo, 2022, doi:<a
    href="https://doi.org/10.5281/ZENODO.8408897">10.5281/ZENODO.8408897</a>.'
  short: M. Zemlicka, E. Redchenko, M. Peruzzo, F. Hassani, A. Trioni, S. Barzanjeh,
    J.M. Fink, (2022).
corr_author: '1'
date_created: 2023-11-13T08:09:10Z
date_published: 2022-06-28T00:00:00Z
date_updated: 2026-06-03T07:16:02Z
day: '28'
ddc:
- '530'
department:
- _id: JoFi
doi: 10.5281/ZENODO.8408897
has_accepted_license: '1'
license: https://creativecommons.org/publicdomain/zero/1.0/
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5281/ZENODO.8408897
month: '06'
oa: 1
oa_version: Published Version
publisher: Zenodo
related_material:
  record:
  - id: '14517'
    relation: used_in_publication
    status: public
status: public
title: 'Compact vacuum gap transmon qubits: Selective and sensitive probes for superconductor
  surface losses'
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2022'
...
---
_id: '11447'
abstract:
- lang: eng
  text: Empirical essays of fitness landscapes suggest that they may be rugged, that
    is having multiple fitness peaks. Such fitness landscapes, those that have multiple
    peaks, necessarily have special local structures, called reciprocal sign epistasis
    (Poelwijk et al. in J Theor Biol 272:141–144, 2011). Here, we investigate the
    quantitative relationship between the number of fitness peaks and the number of
    reciprocal sign epistatic interactions. Previously, it has been shown (Poelwijk
    et al. in J Theor Biol 272:141–144, 2011) that pairwise reciprocal sign epistasis
    is a necessary but not sufficient condition for the existence of multiple peaks.
    Applying discrete Morse theory, which to our knowledge has never been used in
    this context, we extend this result by giving the minimal number of reciprocal
    sign epistatic interactions required to create a given number of peaks.
acknowledgement: We are grateful to Herbert Edelsbrunner and Jeferson Zapata for helpful
  discussions. Open access funding provided by Austrian Science Fund (FWF). Partially
  supported by the ERC Consolidator (771209–CharFL) and the FWF Austrian Science Fund
  (I5127-B) grants to FAK.
article_number: '74'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Raimundo J
  full_name: Saona Urmeneta, Raimundo J
  id: BD1DF4C4-D767-11E9-B658-BC13E6697425
  last_name: Saona Urmeneta
  orcid: 0000-0001-5103-038X
- first_name: Fyodor
  full_name: Kondrashov, Fyodor
  id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
  last_name: Kondrashov
  orcid: 0000-0001-8243-4694
- first_name: Kseniia
  full_name: Khudiakova, Kseniia
  id: 4E6DC800-AE37-11E9-AC72-31CAE5697425
  last_name: Khudiakova
  orcid: 0000-0002-6246-1465
citation:
  ama: Saona Urmeneta RJ, Kondrashov F, Khudiakova K. Relation between the number
    of peaks and the number of reciprocal sign epistatic interactions. <i>Bulletin
    of Mathematical Biology</i>. 2022;84(8). doi:<a href="https://doi.org/10.1007/s11538-022-01029-z">10.1007/s11538-022-01029-z</a>
  apa: Saona Urmeneta, R. J., Kondrashov, F., &#38; Khudiakova, K. (2022). Relation
    between the number of peaks and the number of reciprocal sign epistatic interactions.
    <i>Bulletin of Mathematical Biology</i>. Springer Nature. <a href="https://doi.org/10.1007/s11538-022-01029-z">https://doi.org/10.1007/s11538-022-01029-z</a>
  chicago: Saona Urmeneta, Raimundo J, Fyodor Kondrashov, and Kseniia Khudiakova.
    “Relation between the Number of Peaks and the Number of Reciprocal Sign Epistatic
    Interactions.” <i>Bulletin of Mathematical Biology</i>. Springer Nature, 2022.
    <a href="https://doi.org/10.1007/s11538-022-01029-z">https://doi.org/10.1007/s11538-022-01029-z</a>.
  ieee: R. J. Saona Urmeneta, F. Kondrashov, and K. Khudiakova, “Relation between
    the number of peaks and the number of reciprocal sign epistatic interactions,”
    <i>Bulletin of Mathematical Biology</i>, vol. 84, no. 8. Springer Nature, 2022.
  ista: Saona Urmeneta RJ, Kondrashov F, Khudiakova K. 2022. Relation between the
    number of peaks and the number of reciprocal sign epistatic interactions. Bulletin
    of Mathematical Biology. 84(8), 74.
  mla: Saona Urmeneta, Raimundo J., et al. “Relation between the Number of Peaks and
    the Number of Reciprocal Sign Epistatic Interactions.” <i>Bulletin of Mathematical
    Biology</i>, vol. 84, no. 8, 74, Springer Nature, 2022, doi:<a href="https://doi.org/10.1007/s11538-022-01029-z">10.1007/s11538-022-01029-z</a>.
  short: R.J. Saona Urmeneta, F. Kondrashov, K. Khudiakova, Bulletin of Mathematical
    Biology 84 (2022).
corr_author: '1'
date_created: 2022-06-17T16:16:15Z
date_published: 2022-06-17T00:00:00Z
date_updated: 2026-06-12T12:43:34Z
day: '17'
ddc:
- '510'
- '570'
department:
- _id: GradSch
- _id: NiBa
- _id: JaMa
doi: 10.1007/s11538-022-01029-z
ec_funded: 1
external_id:
  isi:
  - '000812509800001'
  pmid:
  - '35713756'
file:
- access_level: open_access
  checksum: 05a1fe7d10914a00c2bca9b447993a65
  content_type: application/pdf
  creator: dernst
  date_created: 2022-06-20T07:51:32Z
  date_updated: 2022-06-20T07:51:32Z
  file_id: '11455'
  file_name: 2022_BulletinMathBiology_Saona.pdf
  file_size: 463025
  relation: main_file
  success: 1
file_date_updated: 2022-06-20T07:51:32Z
has_accepted_license: '1'
intvolume: '        84'
isi: 1
issue: '8'
keyword:
- Computational Theory and Mathematics
- General Agricultural and Biological Sciences
- Pharmacology
- General Environmental Science
- General Biochemistry
- Genetics and Molecular Biology
- General Mathematics
- Immunology
- General Neuroscience
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 26580278-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '771209'
  name: Characterizing the fitness landscape on population and global scales
- _id: 34e076d6-11ca-11ed-8bc3-aec76c41a181
  grant_number: I05127
  name: Evolutionary analysis of gene regulation
publication: Bulletin of Mathematical Biology
publication_identifier:
  eissn:
  - 1522-9602
  issn:
  - 0092-8240
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - relation: erratum
    url: https://doi.org/10.1007/s11538-022-01118-z
  record:
  - id: '21918'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Relation between the number of peaks and the number of reciprocal sign epistatic
  interactions
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 84
year: '2022'
...
---
_id: '10016'
abstract:
- lang: eng
  text: 'Auxin has always been at the forefront of research in plant physiology and
    development. Since the earliest contemplations by Julius von Sachs and Charles
    Darwin, more than a century-long struggle has been waged to understand its function.
    This largely reflects the failures, successes, and inevitable progress in the
    entire field of plant signaling and development. Here I present 14 stations on
    our long and sometimes mystical journey to understand auxin. These highlights
    were selected to give a flavor of the field and to show the scope and limits of
    our current knowledge. A special focus is put on features that make auxin unique
    among phytohormones, such as its dynamic, directional transport network, which
    integrates external and internal signals, including self-organizing feedback.
    Accented are persistent mysteries and controversies. The unexpected discoveries
    related to rapid auxin responses and growth regulation recently disturbed our
    contentment regarding understanding of the auxin signaling mechanism. These new
    revelations, along with advances in technology, usher us into a new, exciting
    era in auxin research. '
acknowledgement: "The author thanks the whole community of researchers consciously
  or unconsciously working on questions related to auxin, whose hard work and enthusiasm
  contributed to development of this exciting story. Particular thanks go to many\r\nbrilliant
  present and past members of the Friml group and our numerous excellent collaborators,
  without whom my own personal journey would not be possible. The way of the cross
  with its 14 stations is a popular devotion among Roman Catholics and inspires them
  to make a spiritual pilgrimage through contemplation of Christ on his last day.
  Its aspects of gradual progress, struggle, passion, and revelation served as an
  inspiration for the formal depiction of our journey to understanding auxin as described
  in this review. It is in no way intended to reflect the personal beliefs of the
  author and readers. I am grateful to Nick Barton, Eva Benková, Lenka Caisová, Matyáš
  Fendrych, Lukáš Fiedler, Monika Frátriková, Jarmila Frimlová, Michelle Gallei, Jakub
  Hajný, Lukas Hoermayer, Alexandra Mally, Ondrˇej Novák, Jan Petrášek, Aleš Pěnčík,
  Steffen Vanneste, Tongda Xu, and Zhenbiao Yang for their valuable comments. Special
  thanks go to Michelle Gallei for her invaluable assistance with the figures."
article_number: a039859
article_processing_charge: No
article_type: review
author:
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Friml J. Fourteen stations of auxin. <i>Cold Spring Harbor Perspectives in
    Biology</i>. 2022;14(5). doi:<a href="https://doi.org/10.1101/cshperspect.a039859">10.1101/cshperspect.a039859</a>
  apa: Friml, J. (2022). Fourteen stations of auxin. <i>Cold Spring Harbor Perspectives
    in Biology</i>. Cold Spring Harbor Laboratory Press. <a href="https://doi.org/10.1101/cshperspect.a039859">https://doi.org/10.1101/cshperspect.a039859</a>
  chicago: Friml, Jiří. “Fourteen Stations of Auxin.” <i>Cold Spring Harbor Perspectives
    in Biology</i>. Cold Spring Harbor Laboratory Press, 2022. <a href="https://doi.org/10.1101/cshperspect.a039859">https://doi.org/10.1101/cshperspect.a039859</a>.
  ieee: J. Friml, “Fourteen stations of auxin,” <i>Cold Spring Harbor Perspectives
    in Biology</i>, vol. 14, no. 5. Cold Spring Harbor Laboratory Press, 2022.
  ista: Friml J. 2022. Fourteen stations of auxin. Cold Spring Harbor Perspectives
    in Biology. 14(5), a039859.
  mla: Friml, Jiří. “Fourteen Stations of Auxin.” <i>Cold Spring Harbor Perspectives
    in Biology</i>, vol. 14, no. 5, a039859, Cold Spring Harbor Laboratory Press,
    2022, doi:<a href="https://doi.org/10.1101/cshperspect.a039859">10.1101/cshperspect.a039859</a>.
  short: J. Friml, Cold Spring Harbor Perspectives in Biology 14 (2022).
corr_author: '1'
date_created: 2021-09-14T11:36:53Z
date_published: 2022-05-27T00:00:00Z
date_updated: 2026-06-18T08:35:48Z
day: '27'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1101/cshperspect.a039859
external_id:
  isi:
  - '000806563000003'
  pmid:
  - '34400554'
intvolume: '        14'
isi: 1
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: 'https://doi.org/10.1101/cshperspect.a039859 '
month: '05'
oa: 1
oa_version: Published Version
pmid: 1
publication: Cold Spring Harbor Perspectives in Biology
publication_identifier:
  issn:
  - 1943-0264
publication_status: published
publisher: Cold Spring Harbor Laboratory Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Fourteen stations of auxin
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 14
year: '2022'
...
---
_id: '10181'
abstract:
- lang: eng
  text: In this article we study some geometric properties of proximally smooth sets.
    First, we introduce a modification of the metric projection and prove its existence.
    Then we provide an algorithm for constructing a rectifiable curve between two
    sufficiently close points of a proximally smooth set in a uniformly convex and
    uniformly smooth Banach space, with the moduli of smoothness and convexity of
    power type. Our algorithm returns a reasonably short curve between two sufficiently
    close points of a proximally smooth set, is iterative and uses our modification
    of the metric projection. We estimate the length of the constructed curve and
    its deviation from the segment with the same endpoints. These estimates coincide
    up to a constant factor with those for the geodesics in a proximally smooth set
    in a Hilbert space.
acknowledgement: Theorem 2 was obtained at Steklov Mathematical Institute RAS and
  supported by Russian Science Foundation, grant N 19-11-00087.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Grigory
  full_name: Ivanov, Grigory
  id: 87744F66-5C6F-11EA-AFE0-D16B3DDC885E
  last_name: Ivanov
  orcid: 0000-0002-5021-3982
- first_name: Mariana S.
  full_name: Lopushanski, Mariana S.
  last_name: Lopushanski
citation:
  ama: Ivanov G, Lopushanski MS. Rectifiable curves in proximally smooth sets. <i>Set-Valued
    and Variational Analysis</i>. 2022;30(2):657-675. doi:<a href="https://doi.org/10.1007/s11228-021-00612-1">10.1007/s11228-021-00612-1</a>
  apa: Ivanov, G., &#38; Lopushanski, M. S. (2022). Rectifiable curves in proximally
    smooth sets. <i>Set-Valued and Variational Analysis</i>. Springer Nature. <a href="https://doi.org/10.1007/s11228-021-00612-1">https://doi.org/10.1007/s11228-021-00612-1</a>
  chicago: Ivanov, Grigory, and Mariana S. Lopushanski. “Rectifiable Curves in Proximally
    Smooth Sets.” <i>Set-Valued and Variational Analysis</i>. Springer Nature, 2022.
    <a href="https://doi.org/10.1007/s11228-021-00612-1">https://doi.org/10.1007/s11228-021-00612-1</a>.
  ieee: G. Ivanov and M. S. Lopushanski, “Rectifiable curves in proximally smooth
    sets,” <i>Set-Valued and Variational Analysis</i>, vol. 30, no. 2. Springer Nature,
    pp. 657–675, 2022.
  ista: Ivanov G, Lopushanski MS. 2022. Rectifiable curves in proximally smooth sets.
    Set-Valued and Variational Analysis. 30(2), 657–675.
  mla: Ivanov, Grigory, and Mariana S. Lopushanski. “Rectifiable Curves in Proximally
    Smooth Sets.” <i>Set-Valued and Variational Analysis</i>, vol. 30, no. 2, Springer
    Nature, 2022, pp. 657–75, doi:<a href="https://doi.org/10.1007/s11228-021-00612-1">10.1007/s11228-021-00612-1</a>.
  short: G. Ivanov, M.S. Lopushanski, Set-Valued and Variational Analysis 30 (2022)
    657–675.
date_created: 2021-10-24T22:01:35Z
date_published: 2022-06-01T00:00:00Z
date_updated: 2026-06-18T08:36:30Z
day: '01'
ddc:
- '500'
department:
- _id: UlWa
doi: 10.1007/s11228-021-00612-1
external_id:
  arxiv:
  - '2012.10691'
  isi:
  - '000705774800001'
intvolume: '        30'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2012.10691
month: '06'
oa: 1
oa_version: Published Version
page: 657-675
publication: Set-Valued and Variational Analysis
publication_identifier:
  eissn:
  - 1877-0541
  issn:
  - 0927-6947
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Rectifiable curves in proximally smooth sets
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 30
year: '2022'
...
---
_id: '10639'
abstract:
- lang: eng
  text: With more than 80 members worldwide, the Orthobunyavirus genus in the Peribunyaviridae
    family is a large genus of enveloped RNA viruses, many of which are emerging pathogens
    in humans and livestock. How orthobunyaviruses (OBVs) penetrate and infect mammalian
    host cells remains poorly characterized. Here, we investigated the entry mechanisms
    of the OBV Germiston (GERV). Viral particles were visualized by cryo-electron
    microscopy and appeared roughly spherical with an average diameter of 98 nm. Labeling
    of the virus with fluorescent dyes did not adversely affect its infectivity and
    allowed the monitoring of single particles in fixed and live cells. Using this
    approach, we found that endocytic internalization of bound viruses was asynchronous
    and occurred within 30-40 min. The virus entered Rab5a+ early endosomes and, subsequently,
    late endosomal vacuoles containing Rab7a but not LAMP-1. Infectious entry did
    not require proteolytic cleavage, and endosomal acidification was sufficient and
    necessary for viral fusion. Acid-activated penetration began 15-25 min after initiation
    of virus internalization and relied on maturation of early endosomes to late endosomes.
    The optimal pH for viral membrane fusion was slightly below 6.0, and penetration
    was hampered when the potassium influx was abolished. Overall, our study provides
    real-time visualization of GERV entry into host cells and demonstrates the importance
    of late endosomal maturation in facilitating OBV penetration.
acknowledged_ssus:
- _id: EM-Fac
acknowledgement: This work  was  supported  by  INRAE  starter  funds, Project IDEXLYON  (University  of  Lyon)
  within  the  Programme  Investissements  d’Avenir  (ANR-16-IDEX-0005),  and  FINOVIAO14
  (Fondation  pour  l’Université  de  Lyon),  all  to  P.Y.L.  This  work  was  also  supported  by
  CellNetworks  Research  Group  funds  and  Deutsche  Forschungsgemeinschaft  (DFG)  funding
  (grant  numbers  LO-2338/1-1  and  LO-2338/3-1)  awarded  to  P.Y.L., Austrian  Science  Fund
  (FWF)  grant  P31445  to  F.K.M.S., a  Chinese  Scholarship  Council (CSC;no.  201904910701)
  fellowship  to   Q.X.,  and  a  ministére  de  l’enseignement  supérieur,  de  la  recherche  et  de
  l’innovation (MESRI) doctoral thesis grant to M.D.
article_number: e02146-21
article_processing_charge: No
article_type: original
author:
- first_name: Stefan
  full_name: Windhaber, Stefan
  last_name: Windhaber
- first_name: Qilin
  full_name: Xin, Qilin
  last_name: Xin
- first_name: Zina M.
  full_name: Uckeley, Zina M.
  last_name: Uckeley
- first_name: Jana
  full_name: Koch, Jana
  last_name: Koch
- first_name: Martin
  full_name: Obr, Martin
  id: 4741CA5A-F248-11E8-B48F-1D18A9856A87
  last_name: Obr
  orcid: 0000-0003-1756-6564
- first_name: Céline
  full_name: Garnier, Céline
  last_name: Garnier
- first_name: Catherine
  full_name: Luengo-Guyonnot, Catherine
  last_name: Luengo-Guyonnot
- first_name: Maëva
  full_name: Duboeuf, Maëva
  last_name: Duboeuf
- first_name: Florian KM
  full_name: Schur, Florian KM
  id: 48AD8942-F248-11E8-B48F-1D18A9856A87
  last_name: Schur
  orcid: 0000-0003-4790-8078
- first_name: Pierre-Yves
  full_name: Lozach, Pierre-Yves
  last_name: Lozach
citation:
  ama: Windhaber S, Xin Q, Uckeley ZM, et al. The Orthobunyavirus Germiston enters
    host cells from late endosomes. <i>Journal of Virology</i>. 2022;96(5). doi:<a
    href="https://doi.org/10.1128/jvi.02146-21">10.1128/jvi.02146-21</a>
  apa: Windhaber, S., Xin, Q., Uckeley, Z. M., Koch, J., Obr, M., Garnier, C., … Lozach,
    P.-Y. (2022). The Orthobunyavirus Germiston enters host cells from late endosomes.
    <i>Journal of Virology</i>. American Society for Microbiology. <a href="https://doi.org/10.1128/jvi.02146-21">https://doi.org/10.1128/jvi.02146-21</a>
  chicago: Windhaber, Stefan, Qilin Xin, Zina M. Uckeley, Jana Koch, Martin Obr, Céline
    Garnier, Catherine Luengo-Guyonnot, Maëva Duboeuf, Florian KM Schur, and Pierre-Yves
    Lozach. “The Orthobunyavirus Germiston Enters Host Cells from Late Endosomes.”
    <i>Journal of Virology</i>. American Society for Microbiology, 2022. <a href="https://doi.org/10.1128/jvi.02146-21">https://doi.org/10.1128/jvi.02146-21</a>.
  ieee: S. Windhaber <i>et al.</i>, “The Orthobunyavirus Germiston enters host cells
    from late endosomes,” <i>Journal of Virology</i>, vol. 96, no. 5. American Society
    for Microbiology, 2022.
  ista: Windhaber S, Xin Q, Uckeley ZM, Koch J, Obr M, Garnier C, Luengo-Guyonnot
    C, Duboeuf M, Schur FK, Lozach P-Y. 2022. The Orthobunyavirus Germiston enters
    host cells from late endosomes. Journal of Virology. 96(5), e02146-21.
  mla: Windhaber, Stefan, et al. “The Orthobunyavirus Germiston Enters Host Cells
    from Late Endosomes.” <i>Journal of Virology</i>, vol. 96, no. 5, e02146-21, American
    Society for Microbiology, 2022, doi:<a href="https://doi.org/10.1128/jvi.02146-21">10.1128/jvi.02146-21</a>.
  short: S. Windhaber, Q. Xin, Z.M. Uckeley, J. Koch, M. Obr, C. Garnier, C. Luengo-Guyonnot,
    M. Duboeuf, F.K. Schur, P.-Y. Lozach, Journal of Virology 96 (2022).
date_created: 2022-01-18T10:04:18Z
date_published: 2022-03-01T00:00:00Z
date_updated: 2026-06-18T08:44:25Z
day: '01'
ddc:
- '570'
department:
- _id: FlSc
doi: 10.1128/jvi.02146-21
external_id:
  isi:
  - '000779305000033'
  pmid:
  - '35019710'
intvolume: '        96'
isi: 1
issue: '5'
keyword:
- virology
- insect science
- immunology
- microbiology
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906410
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 26736D6A-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P31445
  name: Structural conservation and diversity in retroviral capsid
publication: Journal of Virology
publication_identifier:
  eissn:
  - 1098-5514
  issn:
  - 0022-538X
publication_status: published
publisher: American Society for Microbiology
quality_controlled: '1'
scopus_import: '1'
status: public
title: The Orthobunyavirus Germiston enters host cells from late endosomes
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 96
year: '2022'
...
---
_id: '10583'
abstract:
- lang: eng
  text: The synthetic strigolactone (SL) analog, rac-GR24, has been instrumental in
    studying the role of SLs as well as karrikins because it activates the receptors
    DWARF14 (D14) and KARRIKIN INSENSITIVE 2 (KAI2) of their signaling pathways, respectively.
    Treatment with rac-GR24 modifies the root architecture at different levels, such
    as decreasing the lateral root density (LRD), while promoting root hair elongation
    or flavonol accumulation. Previously, we have shown that the flavonol biosynthesis
    is transcriptionally activated in the root by rac-GR24 treatment, but, thus far,
    the molecular players involved in that response have remained unknown. To get
    an in-depth insight into the changes that occur after the compound is perceived
    by the roots, we compared the root transcriptomes of the wild type and the more
    axillary growth2 (max2) mutant, affected in both SL and karrikin signaling pathways,
    with and without rac-GR24 treatment. Quantitative reverse transcription (qRT)-PCR,
    reporter line analysis and mutant phenotyping indicated that the flavonol response
    and the root hair elongation are controlled by the ELONGATED HYPOCOTYL 5 (HY5)
    and MYB12 transcription factors, but HY5, in contrast to MYB12, affects the LRD
    as well. Furthermore, we identified the transcription factors TARGET OF MONOPTEROS
    5 (TMO5) and TMO5 LIKE1 as negative and the Mediator complex as positive regulators
    of the rac-GR24 effect on LRD. Altogether, hereby, we get closer toward understanding
    the molecular mechanisms that underlay the rac-GR24 responses in the root.
acknowledgement: The authors thank Ralf Stracke (Bielefeld University, Bielefeld,
  Germany) for providing the myb mutants and their colleagues Bert De Rybel for the
  tmo5t;mo5l1 double mutant, Boris Parizot for tips on the RNA-seq analysis, Veronique
  Storme for statistical help on both the RNA-seq and lateral root density, and Martine
  De Cock for help in preparing the manuscript.
article_processing_charge: No
article_type: original
author:
- first_name: Sylwia
  full_name: Struk, Sylwia
  last_name: Struk
- first_name: Lukas
  full_name: Braem, Lukas
  last_name: Braem
- first_name: Cedrick
  full_name: Matthys, Cedrick
  last_name: Matthys
- first_name: Alan
  full_name: Walton, Alan
  last_name: Walton
- first_name: Nick
  full_name: Vangheluwe, Nick
  last_name: Vangheluwe
- first_name: Stan
  full_name: Van Praet, Stan
  last_name: Van Praet
- first_name: Lingxiang
  full_name: Jiang, Lingxiang
  last_name: Jiang
- first_name: Pawel
  full_name: Baster, Pawel
  id: 3028BD74-F248-11E8-B48F-1D18A9856A87
  last_name: Baster
- first_name: Carolien
  full_name: De Cuyper, Carolien
  last_name: De Cuyper
- first_name: Francois-Didier
  full_name: Boyer, Francois-Didier
  last_name: Boyer
- first_name: Elisabeth
  full_name: Stes, Elisabeth
  last_name: Stes
- first_name: Tom
  full_name: Beeckman, Tom
  last_name: Beeckman
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Kris
  full_name: Gevaert, Kris
  last_name: Gevaert
- first_name: Sofie
  full_name: Goormachtig, Sofie
  last_name: Goormachtig
citation:
  ama: Struk S, Braem L, Matthys C, et al. Transcriptional analysis in the Arabidopsis
    roots reveals new regulators that link rac-GR24 treatment with changes in flavonol
    accumulation, root hair elongation and lateral root density. <i>Plant &#38; Cell
    Physiology</i>. 2022;63(1):104-119. doi:<a href="https://doi.org/10.1093/pcp/pcab149">10.1093/pcp/pcab149</a>
  apa: Struk, S., Braem, L., Matthys, C., Walton, A., Vangheluwe, N., Van Praet, S.,
    … Goormachtig, S. (2022). Transcriptional analysis in the Arabidopsis roots reveals
    new regulators that link rac-GR24 treatment with changes in flavonol accumulation,
    root hair elongation and lateral root density. <i>Plant &#38; Cell Physiology</i>.
    Oxford University Press. <a href="https://doi.org/10.1093/pcp/pcab149">https://doi.org/10.1093/pcp/pcab149</a>
  chicago: Struk, Sylwia, Lukas Braem, Cedrick Matthys, Alan Walton, Nick Vangheluwe,
    Stan Van Praet, Lingxiang Jiang, et al. “Transcriptional Analysis in the Arabidopsis
    Roots Reveals New Regulators That Link Rac-GR24 Treatment with Changes in Flavonol
    Accumulation, Root Hair Elongation and Lateral Root Density.” <i>Plant &#38; Cell
    Physiology</i>. Oxford University Press, 2022. <a href="https://doi.org/10.1093/pcp/pcab149">https://doi.org/10.1093/pcp/pcab149</a>.
  ieee: S. Struk <i>et al.</i>, “Transcriptional analysis in the Arabidopsis roots
    reveals new regulators that link rac-GR24 treatment with changes in flavonol accumulation,
    root hair elongation and lateral root density,” <i>Plant &#38; Cell Physiology</i>,
    vol. 63, no. 1. Oxford University Press, pp. 104–119, 2022.
  ista: Struk S, Braem L, Matthys C, Walton A, Vangheluwe N, Van Praet S, Jiang L,
    Baster P, De Cuyper C, Boyer F-D, Stes E, Beeckman T, Friml J, Gevaert K, Goormachtig
    S. 2022. Transcriptional analysis in the Arabidopsis roots reveals new regulators
    that link rac-GR24 treatment with changes in flavonol accumulation, root hair
    elongation and lateral root density. Plant &#38; Cell Physiology. 63(1), 104–119.
  mla: Struk, Sylwia, et al. “Transcriptional Analysis in the Arabidopsis Roots Reveals
    New Regulators That Link Rac-GR24 Treatment with Changes in Flavonol Accumulation,
    Root Hair Elongation and Lateral Root Density.” <i>Plant &#38; Cell Physiology</i>,
    vol. 63, no. 1, Oxford University Press, 2022, pp. 104–19, doi:<a href="https://doi.org/10.1093/pcp/pcab149">10.1093/pcp/pcab149</a>.
  short: S. Struk, L. Braem, C. Matthys, A. Walton, N. Vangheluwe, S. Van Praet, L.
    Jiang, P. Baster, C. De Cuyper, F.-D. Boyer, E. Stes, T. Beeckman, J. Friml, K.
    Gevaert, S. Goormachtig, Plant &#38; Cell Physiology 63 (2022) 104–119.
date_created: 2021-12-28T11:44:18Z
date_published: 2022-01-21T00:00:00Z
date_updated: 2026-06-18T08:43:19Z
day: '21'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1093/pcp/pcab149
external_id:
  isi:
  - '000877899400009'
  pmid:
  - '34791413'
intvolume: '        63'
isi: 1
issue: '1'
keyword:
- flavonols
- MAX2
- rac-Gr24
- RNA-seq
- root development
- transcriptional regulation
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1093/pcp/pcab149
month: '01'
oa: 1
oa_version: Published Version
page: 104-119
pmid: 1
publication: Plant & Cell Physiology
publication_identifier:
  eissn:
  - 1471-9053
  issn:
  - 0032-0781
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Transcriptional analysis in the Arabidopsis roots reveals new regulators that
  link rac-GR24 treatment with changes in flavonol accumulation, root hair elongation
  and lateral root density
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 63
year: '2022'
...
---
_id: '10656'
abstract:
- lang: eng
  text: Idealized simulations of the tropical atmosphere have predicted that clouds
    can spontaneously clump together in space, despite perfectly homogeneous settings.
    This phenomenon has been called self-aggregation, and it results in a state where
    a moist cloudy region with intense deep convective storms is surrounded by extremely
    dry subsiding air devoid of deep clouds. We review here the main findings from
    theoretical work and idealized models of this phenomenon, highlighting the physical
    processes believed to play a key role in convective self-aggregation. We also
    review the growing literature on the importance and implications of this phenomenon
    for the tropical atmosphere, notably, for the hydrological cycle and for precipitation
    extremes, in our current and in a warming climate.
acknowledgement: C.M. gratefully acknowledges funding from the European Research Council
  (ERC) under the European Union's Horizon 2020 research and innovation program (Project
  CLUSTER, grant agreement 805041). She also thanks Grand Équipement National de Calcul
  Intensif (GENCI), France, for providing access to their computing platforms at Très
  Grand Centre de Calcul (TGCC). J.O.H. gratefully acknowledges funding from the Villum
  Foundation (grant 13168), the ERC under the Horizon 2020 research and innovation
  program (grant 771859), and the Novo Nordisk Foundation's Interdisciplinary Synergy
  Program (grant NNF19OC0057374). G.C. gratefully acknowledges the support of the
  transregional collaborative research center (SFB/TRR 165) “Waves to Weather” (http://www.wavestoweather.de)
  funded by the German Research Foundation (DFG). D.Y. is supported by a Packard Fellowship
  in Science and Engineering, the France–Berkeley Fund, Laboratory Directed Research
  and Development (LDRD) funding from the Lawrence Berkeley National Laboratory, and
  the US Department of Energy, Office of Science, Office of Biological and Environmental
  Research, Climate and Environmental Sciences Division, Regional and Global Climate
  Modeling Program under award DE-AC02-05CH11231.
article_processing_charge: No
article_type: original
author:
- first_name: Caroline J
  full_name: Muller, Caroline J
  id: f978ccb0-3f7f-11eb-b193-b0e2bd13182b
  last_name: Muller
  orcid: 0000-0001-5836-5350
- first_name: Da
  full_name: Yang, Da
  last_name: Yang
- first_name: George
  full_name: Craig, George
  last_name: Craig
- first_name: Timothy
  full_name: Cronin, Timothy
  last_name: Cronin
- first_name: Benjamin
  full_name: Fildier, Benjamin
  last_name: Fildier
- first_name: Jan O.
  full_name: Haerter, Jan O.
  last_name: Haerter
- first_name: Cathy
  full_name: Hohenegger, Cathy
  last_name: Hohenegger
- first_name: Brian
  full_name: Mapes, Brian
  last_name: Mapes
- first_name: David
  full_name: Randall, David
  last_name: Randall
- first_name: Sara
  full_name: Shamekh, Sara
  last_name: Shamekh
- first_name: Steven C.
  full_name: Sherwood, Steven C.
  last_name: Sherwood
citation:
  ama: Muller CJ, Yang D, Craig G, et al. Spontaneous aggregation of convective storms.
    <i>Annual Review of Fluid Mechanics</i>. 2022;54:133-157. doi:<a href="https://doi.org/10.1146/annurev-fluid-022421-011319">10.1146/annurev-fluid-022421-011319</a>
  apa: Muller, C. J., Yang, D., Craig, G., Cronin, T., Fildier, B., Haerter, J. O.,
    … Sherwood, S. C. (2022). Spontaneous aggregation of convective storms. <i>Annual
    Review of Fluid Mechanics</i>. Annual Reviews. <a href="https://doi.org/10.1146/annurev-fluid-022421-011319">https://doi.org/10.1146/annurev-fluid-022421-011319</a>
  chicago: Muller, Caroline J, Da Yang, George Craig, Timothy Cronin, Benjamin Fildier,
    Jan O. Haerter, Cathy Hohenegger, et al. “Spontaneous Aggregation of Convective
    Storms.” <i>Annual Review of Fluid Mechanics</i>. Annual Reviews, 2022. <a href="https://doi.org/10.1146/annurev-fluid-022421-011319">https://doi.org/10.1146/annurev-fluid-022421-011319</a>.
  ieee: C. J. Muller <i>et al.</i>, “Spontaneous aggregation of convective storms,”
    <i>Annual Review of Fluid Mechanics</i>, vol. 54. Annual Reviews, pp. 133–157,
    2022.
  ista: Muller CJ, Yang D, Craig G, Cronin T, Fildier B, Haerter JO, Hohenegger C,
    Mapes B, Randall D, Shamekh S, Sherwood SC. 2022. Spontaneous aggregation of convective
    storms. Annual Review of Fluid Mechanics. 54, 133–157.
  mla: Muller, Caroline J., et al. “Spontaneous Aggregation of Convective Storms.”
    <i>Annual Review of Fluid Mechanics</i>, vol. 54, Annual Reviews, 2022, pp. 133–57,
    doi:<a href="https://doi.org/10.1146/annurev-fluid-022421-011319">10.1146/annurev-fluid-022421-011319</a>.
  short: C.J. Muller, D. Yang, G. Craig, T. Cronin, B. Fildier, J.O. Haerter, C. Hohenegger,
    B. Mapes, D. Randall, S. Shamekh, S.C. Sherwood, Annual Review of Fluid Mechanics
    54 (2022) 133–157.
corr_author: '1'
date_created: 2022-01-23T23:01:29Z
date_published: 2022-01-01T00:00:00Z
date_updated: 2026-06-18T08:46:40Z
day: '01'
ddc:
- '550'
department:
- _id: CaMu
doi: 10.1146/annurev-fluid-022421-011319
ec_funded: 1
external_id:
  isi:
  - '000794152800006'
intvolume: '        54'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1146/annurev-fluid-022421-011319
month: '01'
oa: 1
oa_version: Published Version
page: 133-157
project:
- _id: 629205d8-2b32-11ec-9570-e1356ff73576
  call_identifier: H2020
  grant_number: '805041'
  name: Organization of CLoUdS, and implications of Tropical  cyclones and for the
    Energetics of the tropics, in current and waRming climate
publication: Annual Review of Fluid Mechanics
publication_identifier:
  eissn:
  - 1545-4479
  issn:
  - 0066-4189
publication_status: published
publisher: Annual Reviews
quality_controlled: '1'
scopus_import: '1'
status: public
title: Spontaneous aggregation of convective storms
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 54
year: '2022'
...
---
_id: '10719'
abstract:
- lang: eng
  text: Auxin, one of the first identified and most widely studied phytohormones,
    has been and will remain a hot topic in plant biology. After more than a century
    of passionate exploration, the mysteries of its synthesis, transport, signaling,
    and metabolism have largely been unlocked. Due to the rapid development of new
    technologies, new methods, and new genetic materials, the study of auxin has entered
    the fast lane over the past 30 years. Here, we highlight advances in understanding
    auxin signaling, including auxin perception, rapid auxin responses, TRANSPORT
    INHIBITOR RESPONSE 1 and AUXIN SIGNALING F-boxes (TIR1/AFBs)-mediated transcriptional
    and non-transcriptional branches, and the epigenetic regulation of auxin signaling.
    We also focus on feedback inhibition mechanisms that prevent the over-amplification
    of auxin signals. In addition, we cover the TRANSMEMBRANE KINASEs (TMKs)-mediated
    non-canonical signaling, which converges with TIR1/AFBs-mediated transcriptional
    regulation to coordinate plant growth and development. The identification of additional
    auxin signaling components and their regulation will continue to open new avenues
    of research in this field, leading to an increasingly deeper, more comprehensive
    understanding of how auxin signals are interpreted at the cellular level to regulate
    plant growth and development.
acknowledgement: "This research was financially supported by the National Natural
  Science Foundation of China and the Israel Science Foundation (NSFC-ISF; 32061143005),
  National Natural Science Foundation of China (32000225), Natural Science Foundation
  of Shandong Province (ZR2020QC036), and China Postdoctoral Science Foundation (2020M682165).\r\n"
article_processing_charge: No
article_type: review
author:
- first_name: Z
  full_name: Yu, Z
  last_name: Yu
- first_name: F
  full_name: Zhang, F
  last_name: Zhang
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Z
  full_name: Ding, Z
  last_name: Ding
citation:
  ama: 'Yu Z, Zhang F, Friml J, Ding Z. Auxin signaling: Research advances over the
    past 30 years. <i>Journal of Integrative Plant Biology</i>. 2022;64(2):371-392.
    doi:<a href="https://doi.org/10.1111/jipb.13225">10.1111/jipb.13225</a>'
  apa: 'Yu, Z., Zhang, F., Friml, J., &#38; Ding, Z. (2022). Auxin signaling: Research
    advances over the past 30 years. <i>Journal of Integrative Plant Biology</i>.
    Wiley. <a href="https://doi.org/10.1111/jipb.13225">https://doi.org/10.1111/jipb.13225</a>'
  chicago: 'Yu, Z, F Zhang, Jiří Friml, and Z Ding. “Auxin Signaling: Research Advances
    over the Past 30 Years.” <i>Journal of Integrative Plant Biology</i>. Wiley, 2022.
    <a href="https://doi.org/10.1111/jipb.13225">https://doi.org/10.1111/jipb.13225</a>.'
  ieee: 'Z. Yu, F. Zhang, J. Friml, and Z. Ding, “Auxin signaling: Research advances
    over the past 30 years,” <i>Journal of Integrative Plant Biology</i>, vol. 64,
    no. 2. Wiley, pp. 371–392, 2022.'
  ista: 'Yu Z, Zhang F, Friml J, Ding Z. 2022. Auxin signaling: Research advances
    over the past 30 years. Journal of Integrative Plant Biology. 64(2), 371–392.'
  mla: 'Yu, Z., et al. “Auxin Signaling: Research Advances over the Past 30 Years.”
    <i>Journal of Integrative Plant Biology</i>, vol. 64, no. 2, Wiley, 2022, pp.
    371–92, doi:<a href="https://doi.org/10.1111/jipb.13225">10.1111/jipb.13225</a>.'
  short: Z. Yu, F. Zhang, J. Friml, Z. Ding, Journal of Integrative Plant Biology
    64 (2022) 371–392.
corr_author: '1'
date_created: 2022-02-03T09:52:59Z
date_published: 2022-02-01T00:00:00Z
date_updated: 2026-06-18T08:47:21Z
day: '01'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1111/jipb.13225
external_id:
  isi:
  - '000761281200011'
  pmid:
  - '35018726'
intvolume: '        64'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1111/jipb.13225
month: '02'
oa: 1
oa_version: Published Version
page: 371-392
pmid: 1
publication: Journal of Integrative Plant Biology
publication_identifier:
  eissn:
  - 1744-7909
  issn:
  - 1672-9072
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Auxin signaling: Research advances over the past 30 years'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 64
year: '2022'
...
---
_id: '10753'
abstract:
- lang: eng
  text: This is a comment on "Meta-learning synaptic plasticity and memory addressing
    for continual familiarity detection." Neuron. 2022 Feb 2;110(3):544-557.e8.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Basile J
  full_name: Confavreux, Basile J
  id: C7610134-B532-11EA-BD9F-F5753DDC885E
  last_name: Confavreux
- first_name: Tim P
  full_name: Vogels, Tim P
  id: CB6FF8D2-008F-11EA-8E08-2637E6697425
  last_name: Vogels
  orcid: 0000-0003-3295-6181
citation:
  ama: 'Confavreux BJ, Vogels TP. A familiar thought: Machines that replace us? <i>Neuron</i>.
    2022;110(3):361-362. doi:<a href="https://doi.org/10.1016/j.neuron.2022.01.014">10.1016/j.neuron.2022.01.014</a>'
  apa: 'Confavreux, B. J., &#38; Vogels, T. P. (2022). A familiar thought: Machines
    that replace us? <i>Neuron</i>. Elsevier. <a href="https://doi.org/10.1016/j.neuron.2022.01.014">https://doi.org/10.1016/j.neuron.2022.01.014</a>'
  chicago: 'Confavreux, Basile J, and Tim P Vogels. “A Familiar Thought: Machines
    That Replace Us?” <i>Neuron</i>. Elsevier, 2022. <a href="https://doi.org/10.1016/j.neuron.2022.01.014">https://doi.org/10.1016/j.neuron.2022.01.014</a>.'
  ieee: 'B. J. Confavreux and T. P. Vogels, “A familiar thought: Machines that replace
    us?,” <i>Neuron</i>, vol. 110, no. 3. Elsevier, pp. 361–362, 2022.'
  ista: 'Confavreux BJ, Vogels TP. 2022. A familiar thought: Machines that replace
    us? Neuron. 110(3), 361–362.'
  mla: 'Confavreux, Basile J., and Tim P. Vogels. “A Familiar Thought: Machines That
    Replace Us?” <i>Neuron</i>, vol. 110, no. 3, Elsevier, 2022, pp. 361–62, doi:<a
    href="https://doi.org/10.1016/j.neuron.2022.01.014">10.1016/j.neuron.2022.01.014</a>.'
  short: B.J. Confavreux, T.P. Vogels, Neuron 110 (2022) 361–362.
corr_author: '1'
date_created: 2022-02-13T23:01:34Z
date_published: 2022-02-02T00:00:00Z
date_updated: 2026-06-18T08:47:45Z
day: '02'
ddc:
- '570'
department:
- _id: TiVo
doi: 10.1016/j.neuron.2022.01.014
external_id:
  isi:
  - '000751819100005'
  pmid:
  - '35114107'
intvolume: '       110'
isi: 1
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.neuron.2022.01.014
month: '02'
oa: 1
oa_version: Published Version
page: 361-362
pmid: 1
publication: Neuron
publication_identifier:
  eissn:
  - 1097-4199
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'A familiar thought: Machines that replace us?'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 110
year: '2022'
...
---
_id: '10889'
abstract:
- lang: eng
  text: Genetically encoded tags have introduced extensive lines of application from
    purification of tagged proteins to their visualization at the single molecular,
    cellular, histological and whole-body levels. Combined with other rapidly developing
    technologies such as clustered regularly interspaced palindromic repeats (CRISPR)/CRISPR-associated
    protein 9 (Cas9) system, proteomics, super-resolution microscopy and proximity
    labeling, a large variety of genetically encoded tags have been developed in the
    last two decades. In this review, I focus on the current status of tag development
    for electron microscopic (EM) visualization of proteins with metal particle labeling.
    Compared with conventional immunoelectron microscopy using gold particles, tag-mediated
    metal particle labeling has several advantages that could potentially improve
    the sensitivity, spatial and temporal resolution, and applicability to a wide
    range of proteins of interest (POIs). It may enable researchers to detect single
    molecules in situ, allowing the quantitative measurement of absolute numbers and
    exact localization patterns of POI in the ultrastructural context. Thus, genetically
    encoded tags for EM could revolutionize the field as green fluorescence protein
    did for light microscopy, although we still have many challenges to overcome before
    reaching this goal.
acknowledgement: European Research Council Advanced Grant (694539 to R.S.).
article_processing_charge: No
article_type: original
author:
- first_name: Ryuichi
  full_name: Shigemoto, Ryuichi
  id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
  last_name: Shigemoto
  orcid: 0000-0001-8761-9444
citation:
  ama: Shigemoto R. Electron microscopic visualization of single molecules by tag-mediated
    metal particle labeling. <i>Microscopy</i>. 2022;71(Supplement_1):i72-i80. doi:<a
    href="https://doi.org/10.1093/jmicro/dfab048">10.1093/jmicro/dfab048</a>
  apa: Shigemoto, R. (2022). Electron microscopic visualization of single molecules
    by tag-mediated metal particle labeling. <i>Microscopy</i>. Oxford University
    Press. <a href="https://doi.org/10.1093/jmicro/dfab048">https://doi.org/10.1093/jmicro/dfab048</a>
  chicago: Shigemoto, Ryuichi. “Electron Microscopic Visualization of Single Molecules
    by Tag-Mediated Metal Particle Labeling.” <i>Microscopy</i>. Oxford University
    Press, 2022. <a href="https://doi.org/10.1093/jmicro/dfab048">https://doi.org/10.1093/jmicro/dfab048</a>.
  ieee: R. Shigemoto, “Electron microscopic visualization of single molecules by tag-mediated
    metal particle labeling,” <i>Microscopy</i>, vol. 71, no. Supplement_1. Oxford
    University Press, pp. i72–i80, 2022.
  ista: Shigemoto R. 2022. Electron microscopic visualization of single molecules
    by tag-mediated metal particle labeling. Microscopy. 71(Supplement_1), i72–i80.
  mla: Shigemoto, Ryuichi. “Electron Microscopic Visualization of Single Molecules
    by Tag-Mediated Metal Particle Labeling.” <i>Microscopy</i>, vol. 71, no. Supplement_1,
    Oxford University Press, 2022, pp. i72–80, doi:<a href="https://doi.org/10.1093/jmicro/dfab048">10.1093/jmicro/dfab048</a>.
  short: R. Shigemoto, Microscopy 71 (2022) i72–i80.
corr_author: '1'
date_created: 2022-03-20T23:01:39Z
date_published: 2022-03-01T00:00:00Z
date_updated: 2026-06-18T10:44:57Z
day: '01'
ddc:
- '570'
department:
- _id: RySh
doi: 10.1093/jmicro/dfab048
ec_funded: 1
external_id:
  isi:
  - '000768384100011'
  pmid:
  - '35275179'
intvolume: '        71'
isi: 1
issue: Supplement_1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1093/jmicro/dfab048
month: '03'
oa: 1
oa_version: Published Version
page: i72-i80
pmid: 1
project:
- _id: 25CA28EA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '694539'
  name: 'In situ analysis of single channel subunit composition in neurons: physiological
    implication in synaptic plasticity and behaviour'
publication: Microscopy
publication_identifier:
  eissn:
  - 2050-5701
  issn:
  - 2050-5698
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Electron microscopic visualization of single molecules by tag-mediated metal
  particle labeling
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 71
year: '2022'
...
---
_id: '10846'
abstract:
- lang: eng
  text: The Golgi apparatus regulates the process of modification and subcellular
    localization of macromolecules, including proteins and lipids. Aberrant protein
    sorting caused by defects in the Golgi leads to various diseases in mammals. However,
    the role of the Golgi apparatus in organismal longevity remained largely unknown.
    By employing a quantitative proteomic approach, we demonstrated that MON-2, an
    evolutionarily conserved Arf-GEF protein implicated in Golgi-to-endosome trafficking,
    promotes longevity via upregulating macroautophagy/autophagy in C. elegans. Our
    data using cultured mammalian cells indicate that MON2 translocates from the Golgi
    to the endosome under starvation conditions, subsequently increasing autophagic
    flux by binding LGG-1/GABARAPL2. Thus, Golgi-to-endosome trafficking appears to
    be an evolutionarily conserved process for the upregulation of autophagy, which
    contributes to organismal longevity.
acknowledgement: This work is funded by National Research Foundation of Korea (NRF)
  grants NRF-2019R1A3B2067745 from the Korean Government (Ministry of Science and
  Information and Communications Technology (S-J.V.L.). NRF-2017R1A5A1015366 (S.Y.P,
  S-J.V.L). Korea Institute of Science and Technology (KIST) intramural grant (C.L).
article_processing_charge: No
article_type: original
author:
- first_name: Murat
  full_name: Artan, Murat
  id: C407B586-6052-11E9-B3AE-7006E6697425
  last_name: Artan
  orcid: 0000-0001-8945-6992
- first_name: Jooyeon
  full_name: Sohn, Jooyeon
  last_name: Sohn
- first_name: Cheolju
  full_name: Lee, Cheolju
  last_name: Lee
- first_name: Seung Yeol
  full_name: Park, Seung Yeol
  last_name: Park
- first_name: Seung Jae V.
  full_name: Lee, Seung Jae V.
  last_name: Lee
citation:
  ama: Artan M, Sohn J, Lee C, Park SY, Lee SJV. MON-2, a Golgi protein, promotes
    longevity by upregulating autophagy through mediating inter-organelle communications.
    <i>Autophagy</i>. 2022;18(5):1208-1210. doi:<a href="https://doi.org/10.1080/15548627.2022.2039523">10.1080/15548627.2022.2039523</a>
  apa: Artan, M., Sohn, J., Lee, C., Park, S. Y., &#38; Lee, S. J. V. (2022). MON-2,
    a Golgi protein, promotes longevity by upregulating autophagy through mediating
    inter-organelle communications. <i>Autophagy</i>. Taylor &#38; Francis. <a href="https://doi.org/10.1080/15548627.2022.2039523">https://doi.org/10.1080/15548627.2022.2039523</a>
  chicago: Artan, Murat, Jooyeon Sohn, Cheolju Lee, Seung Yeol Park, and Seung Jae
    V. Lee. “MON-2, a Golgi Protein, Promotes Longevity by Upregulating Autophagy
    through Mediating Inter-Organelle Communications.” <i>Autophagy</i>. Taylor &#38;
    Francis, 2022. <a href="https://doi.org/10.1080/15548627.2022.2039523">https://doi.org/10.1080/15548627.2022.2039523</a>.
  ieee: M. Artan, J. Sohn, C. Lee, S. Y. Park, and S. J. V. Lee, “MON-2, a Golgi protein,
    promotes longevity by upregulating autophagy through mediating inter-organelle
    communications,” <i>Autophagy</i>, vol. 18, no. 5. Taylor &#38; Francis, pp. 1208–1210,
    2022.
  ista: Artan M, Sohn J, Lee C, Park SY, Lee SJV. 2022. MON-2, a Golgi protein, promotes
    longevity by upregulating autophagy through mediating inter-organelle communications.
    Autophagy. 18(5), 1208–1210.
  mla: Artan, Murat, et al. “MON-2, a Golgi Protein, Promotes Longevity by Upregulating
    Autophagy through Mediating Inter-Organelle Communications.” <i>Autophagy</i>,
    vol. 18, no. 5, Taylor &#38; Francis, 2022, pp. 1208–10, doi:<a href="https://doi.org/10.1080/15548627.2022.2039523">10.1080/15548627.2022.2039523</a>.
  short: M. Artan, J. Sohn, C. Lee, S.Y. Park, S.J.V. Lee, Autophagy 18 (2022) 1208–1210.
date_created: 2022-03-13T23:01:47Z
date_published: 2022-02-19T00:00:00Z
date_updated: 2026-06-18T10:40:40Z
day: '19'
ddc:
- '570'
department:
- _id: MaDe
doi: 10.1080/15548627.2022.2039523
external_id:
  isi:
  - '000758859600001'
  pmid:
  - '35188063'
intvolume: '        18'
isi: 1
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1080/15548627.2022.2039523
month: '02'
oa: 1
oa_version: Published Version
page: 1208-1210
pmid: 1
publication: Autophagy
publication_identifier:
  eissn:
  - 1554-8635
  issn:
  - 1554-8627
publication_status: published
publisher: Taylor & Francis
quality_controlled: '1'
scopus_import: '1'
status: public
title: MON-2, a Golgi protein, promotes longevity by upregulating autophagy through
  mediating inter-organelle communications
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 18
year: '2022'
...
---
_id: '11187'
abstract:
- lang: eng
  text: During the COVID-19 pandemic, genomics and bioinformatics have emerged as
    essential public health tools. The genomic data acquired using these methods have
    supported the global health response, facilitated the development of testing methods
    and allowed the timely tracking of novel SARS-CoV-2 variants. Yet the virtually
    unlimited potential for rapid generation and analysis of genomic data is also
    coupled with unique technical, scientific and organizational challenges. Here,
    we discuss the application of genomic and computational methods for efficient
    data-driven COVID-19 response, the advantages of the democratization of viral
    sequencing around the world and the challenges associated with viral genome data
    collection and processing.
acknowledgement: 'Our paper is dedicated to all freedom-loving people around the world,
  and to the people of Ukraine who fight for our freedom. We thank William M. Switzer
  and Ellsworth M. Campbell from the Division of HIV/AIDS Prevention, Centers for
  Disease Control and Prevention (CDC), Atlanta, GA, USA, for discussions and suggestions.
  We thank Jason Ladner from the Pathogen and Microbiome Institute, Northern Arizona
  University, Flagstaff, AZ, for providing suggestions and feedback. S.M. was partially
  supported by National Science Foundation grants 2041984. T.L. is supported by the
  NSFC Excellent Young Scientists Fund (Hong Kong and Macau; 31922087), Research Grants
  Council (RGC) Collaborative Research Fund (C7144-20GF), RGC Research Impact Fund
  (R7021-20), Innovation and Technology Commission’s InnoHK funding (D24H) and Health
  and Medical Research Fund (COVID190223). P.S. was supported by US National Institutes
  of Health (NIH) grant 1R01EB025022 and National Science Foundation (NSF) grant 2047828.
  M.A. acknowledges King Abdulaziz City for Science and Technology and the Saudi Human
  Genome Project for technical and financial support (https://shgp.kacst.edu.sa) N.W.
  was supported by US NIH grants R00 AI139445, DP2 AT011966 and R01 AI167910. A.S.
  acknowledge funding from NSF grant no. 2029025. A.Z. has been partially supported
  by NIH grants 1R01EB025022-01 and 1R21CA241044-01A1. S. Knyazev has been partly
  supported by Molecular Basis of Disease at Georgia State University and NIH awards
  R01 HG009120, R01 MH115676, R01 AI153827 and U01 HG011715. A.W. has been supported
  by the CAMS Innovation Fund for Medical Sciences (2021-I2M-1-061). R.K. was supported
  by NSF project 2038509, RAPID: Improving QIIME 2 and UniFrac for Viruses to Respond
  to COVID-19, CDC project 30055281 with Scripps led by Kristian Andersen, Genomic
  sequencing of SARS-CoV-2 to investigate local and cross-border emergence and spread.
  J.O.W. was supported by NIH–National Institute of Allergy and Infectious Diseases
  (NIAID) R01 AI135992 and receives funding from the CDC unrelated to this work. T.I.V.
  is supported by the Branco Weiss Fellowship. Y.P. was supported by the Ministry
  of Science and Higher Education of the Russian Federation within the framework of
  state support for the creation and development of World-Class Research Centers “Digital
  biodesign and personalized healthcare” N◦075-15-2020-926. E.B. was supported by
  a US National Institute of General Medical Sciences IDeA Alaska INBRE (P20GM103395)
  and NIAID CEIRR (75N93019R00028). C.E.M. thanks Testing for America (501c3), OpenCovidScreen
  Foundation, Igor Tulchinsky and the WorldQuant Foundation, Bill Ackman and Olivia
  Flatto and the Pershing Square Foundation, Ken Griffin and Citadel, the US National
  Institutes of Health (R01AI125416, R01AI151059, R21AI129851, U01DA053941), and the
  Alfred P. Sloan Foundation (G-2015-13964). C.Y.C. is supported by US CDC Epidemiology
  and Laboratory Capacity (ELC) for Infectious Diseases grant 6NU50CK000539 to the
  California Department of Public Health, the Innovative Genomics Institute (IGI)
  at the University of California, Berkeley, and University of California, San Francisco,
  NIH grant R33AI12945 and US CDC contract 75D30121C10991. A.K. was partly supported
  by RFBR grant 20-515-80017. P.L. acknowledges support from the European Research
  Council (ERC) under the European Union’s Horizon 2020 research and innovation program
  (grant agreement no. ~725422 - ReservoirDOCS), the Wellcome Trust through project
  206298/Z/17/Z (Artic Network) and NIH grants R01 AI153044 and U19 AI135995. K.C.
  acknowledges support from the US NSF award EEID-IOS-2109688. F.K.’s work was supported
  by an ERC Consolidator grant to F.K. (771209–CharFL).'
article_processing_charge: No
article_type: letter_note
author:
- first_name: Sergey
  full_name: Knyazev, Sergey
  last_name: Knyazev
- first_name: Karishma
  full_name: Chhugani, Karishma
  last_name: Chhugani
- first_name: Varuni
  full_name: Sarwal, Varuni
  last_name: Sarwal
- first_name: Ram
  full_name: Ayyala, Ram
  last_name: Ayyala
- first_name: Harman
  full_name: Singh, Harman
  last_name: Singh
- first_name: Smruthi
  full_name: Karthikeyan, Smruthi
  last_name: Karthikeyan
- first_name: Dhrithi
  full_name: Deshpande, Dhrithi
  last_name: Deshpande
- first_name: Pelin Icer
  full_name: Baykal, Pelin Icer
  last_name: Baykal
- first_name: Zoia
  full_name: Comarova, Zoia
  last_name: Comarova
- first_name: Angela
  full_name: Lu, Angela
  last_name: Lu
- first_name: Yuri
  full_name: Porozov, Yuri
  last_name: Porozov
- first_name: Tetyana I.
  full_name: Vasylyeva, Tetyana I.
  last_name: Vasylyeva
- first_name: Joel O.
  full_name: Wertheim, Joel O.
  last_name: Wertheim
- first_name: Braden T.
  full_name: Tierney, Braden T.
  last_name: Tierney
- first_name: Charles Y.
  full_name: Chiu, Charles Y.
  last_name: Chiu
- first_name: Ren
  full_name: Sun, Ren
  last_name: Sun
- first_name: Aiping
  full_name: Wu, Aiping
  last_name: Wu
- first_name: Malak S.
  full_name: Abedalthagafi, Malak S.
  last_name: Abedalthagafi
- first_name: Victoria M.
  full_name: Pak, Victoria M.
  last_name: Pak
- first_name: Shivashankar H.
  full_name: Nagaraj, Shivashankar H.
  last_name: Nagaraj
- first_name: Adam L.
  full_name: Smith, Adam L.
  last_name: Smith
- first_name: Pavel
  full_name: Skums, Pavel
  last_name: Skums
- first_name: Bogdan
  full_name: Pasaniuc, Bogdan
  last_name: Pasaniuc
- first_name: Andrey
  full_name: Komissarov, Andrey
  last_name: Komissarov
- first_name: Christopher E.
  full_name: Mason, Christopher E.
  last_name: Mason
- first_name: Eric
  full_name: Bortz, Eric
  last_name: Bortz
- first_name: Philippe
  full_name: Lemey, Philippe
  last_name: Lemey
- first_name: Fyodor
  full_name: Kondrashov, Fyodor
  id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
  last_name: Kondrashov
  orcid: 0000-0001-8243-4694
- first_name: Niko
  full_name: Beerenwinkel, Niko
  last_name: Beerenwinkel
- first_name: Tommy Tsan Yuk
  full_name: Lam, Tommy Tsan Yuk
  last_name: Lam
- first_name: Nicholas C.
  full_name: Wu, Nicholas C.
  last_name: Wu
- first_name: Alex
  full_name: Zelikovsky, Alex
  last_name: Zelikovsky
- first_name: Rob
  full_name: Knight, Rob
  last_name: Knight
- first_name: Keith A.
  full_name: Crandall, Keith A.
  last_name: Crandall
- first_name: Serghei
  full_name: Mangul, Serghei
  last_name: Mangul
citation:
  ama: Knyazev S, Chhugani K, Sarwal V, et al. Unlocking capacities of genomics for
    the COVID-19 response and future pandemics. <i>Nature Methods</i>. 2022;19(4):374-380.
    doi:<a href="https://doi.org/10.1038/s41592-022-01444-z">10.1038/s41592-022-01444-z</a>
  apa: Knyazev, S., Chhugani, K., Sarwal, V., Ayyala, R., Singh, H., Karthikeyan,
    S., … Mangul, S. (2022). Unlocking capacities of genomics for the COVID-19 response
    and future pandemics. <i>Nature Methods</i>. Springer Nature. <a href="https://doi.org/10.1038/s41592-022-01444-z">https://doi.org/10.1038/s41592-022-01444-z</a>
  chicago: Knyazev, Sergey, Karishma Chhugani, Varuni Sarwal, Ram Ayyala, Harman Singh,
    Smruthi Karthikeyan, Dhrithi Deshpande, et al. “Unlocking Capacities of Genomics
    for the COVID-19 Response and Future Pandemics.” <i>Nature Methods</i>. Springer
    Nature, 2022. <a href="https://doi.org/10.1038/s41592-022-01444-z">https://doi.org/10.1038/s41592-022-01444-z</a>.
  ieee: S. Knyazev <i>et al.</i>, “Unlocking capacities of genomics for the COVID-19
    response and future pandemics,” <i>Nature Methods</i>, vol. 19, no. 4. Springer
    Nature, pp. 374–380, 2022.
  ista: Knyazev S, Chhugani K, Sarwal V, Ayyala R, Singh H, Karthikeyan S, Deshpande
    D, Baykal PI, Comarova Z, Lu A, Porozov Y, Vasylyeva TI, Wertheim JO, Tierney
    BT, Chiu CY, Sun R, Wu A, Abedalthagafi MS, Pak VM, Nagaraj SH, Smith AL, Skums
    P, Pasaniuc B, Komissarov A, Mason CE, Bortz E, Lemey P, Kondrashov F, Beerenwinkel
    N, Lam TTY, Wu NC, Zelikovsky A, Knight R, Crandall KA, Mangul S. 2022. Unlocking
    capacities of genomics for the COVID-19 response and future pandemics. Nature
    Methods. 19(4), 374–380.
  mla: Knyazev, Sergey, et al. “Unlocking Capacities of Genomics for the COVID-19
    Response and Future Pandemics.” <i>Nature Methods</i>, vol. 19, no. 4, Springer
    Nature, 2022, pp. 374–80, doi:<a href="https://doi.org/10.1038/s41592-022-01444-z">10.1038/s41592-022-01444-z</a>.
  short: S. Knyazev, K. Chhugani, V. Sarwal, R. Ayyala, H. Singh, S. Karthikeyan,
    D. Deshpande, P.I. Baykal, Z. Comarova, A. Lu, Y. Porozov, T.I. Vasylyeva, J.O.
    Wertheim, B.T. Tierney, C.Y. Chiu, R. Sun, A. Wu, M.S. Abedalthagafi, V.M. Pak,
    S.H. Nagaraj, A.L. Smith, P. Skums, B. Pasaniuc, A. Komissarov, C.E. Mason, E.
    Bortz, P. Lemey, F. Kondrashov, N. Beerenwinkel, T.T.Y. Lam, N.C. Wu, A. Zelikovsky,
    R. Knight, K.A. Crandall, S. Mangul, Nature Methods 19 (2022) 374–380.
date_created: 2022-04-17T22:01:48Z
date_published: 2022-04-08T00:00:00Z
date_updated: 2026-06-18T10:47:32Z
day: '08'
ddc:
- '570'
department:
- _id: FyKo
doi: 10.1038/s41592-022-01444-z
ec_funded: 1
external_id:
  isi:
  - '000781199600011'
  pmid:
  - '35396471'
intvolume: '        19'
isi: 1
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1038/s41592-022-01444-z
month: '04'
oa: 1
oa_version: Published Version
page: 374-380
pmid: 1
project:
- _id: 26580278-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '771209'
  name: Characterizing the fitness landscape on population and global scales
publication: Nature Methods
publication_identifier:
  eissn:
  - 1548-7105
  issn:
  - 1548-7091
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Unlocking capacities of genomics for the COVID-19 response and future pandemics
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 19
year: '2022'
...
---
_id: '10925'
abstract:
- lang: eng
  text: Direct numerical simulations (DNS) of turbulent channel flows up to  Reτ≈1000  are
    conducted to investigate the three-dimensional (consisting of streamwise wavenumber,
    spanwise wavenumber and frequency) spectrum of wall pressure fluctuations. To
    develop a predictive model of the wavenumber–frequency spectrum from the wavenumber
    spectrum, the time decorrelation mechanisms of wall pressure fluctuations are
    investigated. It is discovered that the energy-containing part of the wavenumber–frequency
    spectrum of wall pressure fluctuations can be well predicted using a similar random
    sweeping model for streamwise velocity fluctuations. To refine the investigation,
    we further decompose the spectrum of the total wall pressure fluctuations into
    the autospectra of rapid and slow pressure fluctuations, and the cross-spectrum
    between them. We focus on evaluating the assumption applied in many predictive
    models, that is, the magnitude of the cross-spectrum is negligibly small. The
    present DNS shows that neglecting the cross-spectrum causes a maximum error up
    to 4.7 dB in the subconvective region for all Reynolds numbers under test. Our
    analyses indicate that the approximation of neglecting the cross-spectrum needs
    to be applied carefully in the investigations of acoustics at low Mach numbers,
    in which the subconvective components of wall pressure fluctuations make important
    contributions to the radiated acoustic power.
acknowledgement: This research is supported by the NSFC Basic Science Center Program
  for ‘Multiscale Problems in Nonlinear Mechanics’ (no. 11988102), National Key Project
  (GJXM92579) and the Strategic Priority Research Program (XDB22040104).
article_number: A39
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Bowen
  full_name: Yang, Bowen
  id: 71b6ff4b-15b2-11ec-abd3-aef6b028cf7e
  last_name: Yang
  orcid: 0000-0002-4843-6853
- first_name: Zixuan
  full_name: Yang, Zixuan
  last_name: Yang
citation:
  ama: Yang B, Yang Z. On the wavenumber-frequency spectrum of the wall pressure fluctuations
    in turbulent channel flow. <i>Journal of Fluid Mechanics</i>. 2022;937. doi:<a
    href="https://doi.org/10.1017/jfm.2022.137">10.1017/jfm.2022.137</a>
  apa: Yang, B., &#38; Yang, Z. (2022). On the wavenumber-frequency spectrum of the
    wall pressure fluctuations in turbulent channel flow. <i>Journal of Fluid Mechanics</i>.
    Cambridge University Press. <a href="https://doi.org/10.1017/jfm.2022.137">https://doi.org/10.1017/jfm.2022.137</a>
  chicago: Yang, Bowen, and Zixuan Yang. “On the Wavenumber-Frequency Spectrum of
    the Wall Pressure Fluctuations in Turbulent Channel Flow.” <i>Journal of Fluid
    Mechanics</i>. Cambridge University Press, 2022. <a href="https://doi.org/10.1017/jfm.2022.137">https://doi.org/10.1017/jfm.2022.137</a>.
  ieee: B. Yang and Z. Yang, “On the wavenumber-frequency spectrum of the wall pressure
    fluctuations in turbulent channel flow,” <i>Journal of Fluid Mechanics</i>, vol.
    937. Cambridge University Press, 2022.
  ista: Yang B, Yang Z. 2022. On the wavenumber-frequency spectrum of the wall pressure
    fluctuations in turbulent channel flow. Journal of Fluid Mechanics. 937, A39.
  mla: Yang, Bowen, and Zixuan Yang. “On the Wavenumber-Frequency Spectrum of the
    Wall Pressure Fluctuations in Turbulent Channel Flow.” <i>Journal of Fluid Mechanics</i>,
    vol. 937, A39, Cambridge University Press, 2022, doi:<a href="https://doi.org/10.1017/jfm.2022.137">10.1017/jfm.2022.137</a>.
  short: B. Yang, Z. Yang, Journal of Fluid Mechanics 937 (2022).
date_created: 2022-03-27T22:01:45Z
date_published: 2022-04-25T00:00:00Z
date_updated: 2026-06-18T10:46:00Z
day: '25'
ddc:
- '530'
department:
- _id: GradSch
doi: 10.1017/jfm.2022.137
external_id:
  arxiv:
  - '2201.04702'
  isi:
  - '000763547000001'
intvolume: '       937'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1017/jfm.2022.137
month: '04'
oa: 1
oa_version: Published Version
publication: Journal of Fluid Mechanics
publication_identifier:
  eissn:
  - 1469-7645
  issn:
  - 0022-1120
publication_status: published
publisher: Cambridge University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: On the wavenumber-frequency spectrum of the wall pressure fluctuations in turbulent
  channel flow
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 937
year: '2022'
...
---
_id: '11333'
abstract:
- lang: eng
  text: Adenosine triphosphate (ATP) is the energy source for various biochemical
    processes and biomolecular motors in living things. Development of ATP antagonists
    and their stimuli-controlled actions offer a novel approach to regulate biological
    processes. Herein, we developed azobenzene-based photoswitchable ATP antagonists
    for controlling the activity of motor proteins; cytoplasmic and axonemal dyneins.
    The new ATP antagonists showed reversible photoswitching of cytoplasmic dynein
    activity in an in vitro dynein-microtubule system due to the trans and cis photoisomerization
    of their azobenzene segment. Importantly, our ATP antagonists reversibly regulated
    the axonemal dynein motor activity for the force generation in a demembranated
    model of Chlamydomonas reinhardtii. We found that the trans and cis isomers of
    ATP antagonists significantly differ in their affinity to the ATP binding site.
article_number: e202200807
article_processing_charge: No
article_type: original
author:
- first_name: Sampreeth
  full_name: Thayyil, Sampreeth
  last_name: Thayyil
- first_name: Yukinori
  full_name: Nishigami, Yukinori
  last_name: Nishigami
- first_name: Muhammad J
  full_name: Islam, Muhammad J
  id: C94881D2-008F-11EA-8E08-2637E6697425
  last_name: Islam
- first_name: P. K.
  full_name: Hashim, P. K.
  last_name: Hashim
- first_name: Ken'Ya
  full_name: Furuta, Ken'Ya
  last_name: Furuta
- first_name: Kazuhiro
  full_name: Oiwa, Kazuhiro
  last_name: Oiwa
- first_name: Jian
  full_name: Yu, Jian
  last_name: Yu
- first_name: Min
  full_name: Yao, Min
  last_name: Yao
- first_name: Toshiyuki
  full_name: Nakagaki, Toshiyuki
  last_name: Nakagaki
- first_name: Nobuyuki
  full_name: Tamaoki, Nobuyuki
  last_name: Tamaoki
citation:
  ama: Thayyil S, Nishigami Y, Islam MJ, et al. Dynamic control of microbial movement
    by photoswitchable ATP antagonists. <i>Chemistry - A European Journal</i>. 2022;28(30).
    doi:<a href="https://doi.org/10.1002/chem.202200807">10.1002/chem.202200807</a>
  apa: Thayyil, S., Nishigami, Y., Islam, M. J., Hashim, P. K., Furuta, K., Oiwa,
    K., … Tamaoki, N. (2022). Dynamic control of microbial movement by photoswitchable
    ATP antagonists. <i>Chemistry - A European Journal</i>. Wiley. <a href="https://doi.org/10.1002/chem.202200807">https://doi.org/10.1002/chem.202200807</a>
  chicago: Thayyil, Sampreeth, Yukinori Nishigami, Muhammad J Islam, P. K. Hashim,
    Ken’Ya Furuta, Kazuhiro Oiwa, Jian Yu, Min Yao, Toshiyuki Nakagaki, and Nobuyuki
    Tamaoki. “Dynamic Control of Microbial Movement by Photoswitchable ATP Antagonists.”
    <i>Chemistry - A European Journal</i>. Wiley, 2022. <a href="https://doi.org/10.1002/chem.202200807">https://doi.org/10.1002/chem.202200807</a>.
  ieee: S. Thayyil <i>et al.</i>, “Dynamic control of microbial movement by photoswitchable
    ATP antagonists,” <i>Chemistry - A European Journal</i>, vol. 28, no. 30. Wiley,
    2022.
  ista: Thayyil S, Nishigami Y, Islam MJ, Hashim PK, Furuta K, Oiwa K, Yu J, Yao M,
    Nakagaki T, Tamaoki N. 2022. Dynamic control of microbial movement by photoswitchable
    ATP antagonists. Chemistry - A European Journal. 28(30), e202200807.
  mla: Thayyil, Sampreeth, et al. “Dynamic Control of Microbial Movement by Photoswitchable
    ATP Antagonists.” <i>Chemistry - A European Journal</i>, vol. 28, no. 30, e202200807,
    Wiley, 2022, doi:<a href="https://doi.org/10.1002/chem.202200807">10.1002/chem.202200807</a>.
  short: S. Thayyil, Y. Nishigami, M.J. Islam, P.K. Hashim, K. Furuta, K. Oiwa, J.
    Yu, M. Yao, T. Nakagaki, N. Tamaoki, Chemistry - A European Journal 28 (2022).
date_created: 2022-04-24T22:01:44Z
date_published: 2022-05-25T00:00:00Z
date_updated: 2026-06-18T10:49:46Z
day: '25'
ddc:
- '570'
department:
- _id: RySh
doi: 10.1002/chem.202200807
external_id:
  isi:
  - '000781658800001'
  pmid:
  - '35332959'
intvolume: '        28'
isi: 1
issue: '30'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1002/chem.202200807
month: '05'
oa: 1
oa_version: Published Version
pmid: 1
publication: Chemistry - A European Journal
publication_identifier:
  eissn:
  - 1521-3765
  issn:
  - 0947-6539
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Dynamic control of microbial movement by photoswitchable ATP antagonists
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 28
year: '2022'
...
---
_id: '11449'
abstract:
- lang: eng
  text: Mutations are acquired frequently, such that each cell's genome inscribes
    its history of cell divisions. Common genomic alterations involve loss of heterozygosity
    (LOH). LOH accumulates throughout the genome, offering large encoding capacity
    for inferring cell lineage. Using only single-cell RNA sequencing (scRNA-seq)
    of mouse brain cells, we found that LOH events spanning multiple genes are revealed
    as tracts of monoallelically expressed, constitutionally heterozygous single-nucleotide
    variants (SNVs). We simultaneously inferred cell lineage and marked developmental
    time points based on X chromosome inactivation and the total number of LOH events
    while identifying cell types from gene expression patterns. Our results are consistent
    with progenitor cells giving rise to multiple cortical cell types through stereotyped
    expansion and distinct waves of neurogenesis. This type of retrospective analysis
    could be incorporated into scRNA-seq pipelines and, compared with experimental
    approaches for determining lineage in model organisms, is applicable where genetic
    engineering is prohibited, such as humans.
acknowledgement: D.J.A. thanks Wayne K. Potts, Alan R. Rogers, Kristen Hawkes, Ryk
  Ward, and Jon Seger for inspiring a young undergraduate to apply evolutionary theory
  to intraorganism development. Supported by the Paul G. Allen Frontiers Group (University
  of Washington); NIH R00HG010152 (Dartmouth); and NÖ Forschung und Bildung n[f+b]
  life science call grant (C13-002) and the European Research Council (ERC) under
  the European Union’s Horizon 2020 research and innovation program 725780 LinPro
  to S.H.
article_processing_charge: No
article_type: original
author:
- first_name: Donovan J.
  full_name: Anderson, Donovan J.
  last_name: Anderson
- first_name: Florian
  full_name: Pauler, Florian
  id: 48EA0138-F248-11E8-B48F-1D18A9856A87
  last_name: Pauler
  orcid: 0000-0002-7462-0048
- first_name: Aaron
  full_name: Mckenna, Aaron
  last_name: Mckenna
- first_name: Jay
  full_name: Shendure, Jay
  last_name: Shendure
- first_name: Simon
  full_name: Hippenmeyer, Simon
  id: 37B36620-F248-11E8-B48F-1D18A9856A87
  last_name: Hippenmeyer
  orcid: 0000-0003-2279-1061
- first_name: Marshall S.
  full_name: Horwitz, Marshall S.
  last_name: Horwitz
citation:
  ama: Anderson DJ, Pauler F, Mckenna A, Shendure J, Hippenmeyer S, Horwitz MS. Simultaneous
    brain cell type and lineage determined by scRNA-seq reveals stereotyped cortical
    development. <i>Cell Systems</i>. 2022;13(6):438-453.e5. doi:<a href="https://doi.org/10.1016/j.cels.2022.03.006">10.1016/j.cels.2022.03.006</a>
  apa: Anderson, D. J., Pauler, F., Mckenna, A., Shendure, J., Hippenmeyer, S., &#38;
    Horwitz, M. S. (2022). Simultaneous brain cell type and lineage determined by
    scRNA-seq reveals stereotyped cortical development. <i>Cell Systems</i>. Elsevier.
    <a href="https://doi.org/10.1016/j.cels.2022.03.006">https://doi.org/10.1016/j.cels.2022.03.006</a>
  chicago: Anderson, Donovan J., Florian Pauler, Aaron Mckenna, Jay Shendure, Simon
    Hippenmeyer, and Marshall S. Horwitz. “Simultaneous Brain Cell Type and Lineage
    Determined by ScRNA-Seq Reveals Stereotyped Cortical Development.” <i>Cell Systems</i>.
    Elsevier, 2022. <a href="https://doi.org/10.1016/j.cels.2022.03.006">https://doi.org/10.1016/j.cels.2022.03.006</a>.
  ieee: D. J. Anderson, F. Pauler, A. Mckenna, J. Shendure, S. Hippenmeyer, and M.
    S. Horwitz, “Simultaneous brain cell type and lineage determined by scRNA-seq
    reveals stereotyped cortical development,” <i>Cell Systems</i>, vol. 13, no. 6.
    Elsevier, p. 438–453.e5, 2022.
  ista: Anderson DJ, Pauler F, Mckenna A, Shendure J, Hippenmeyer S, Horwitz MS. 2022.
    Simultaneous brain cell type and lineage determined by scRNA-seq reveals stereotyped
    cortical development. Cell Systems. 13(6), 438–453.e5.
  mla: Anderson, Donovan J., et al. “Simultaneous Brain Cell Type and Lineage Determined
    by ScRNA-Seq Reveals Stereotyped Cortical Development.” <i>Cell Systems</i>, vol.
    13, no. 6, Elsevier, 2022, p. 438–453.e5, doi:<a href="https://doi.org/10.1016/j.cels.2022.03.006">10.1016/j.cels.2022.03.006</a>.
  short: D.J. Anderson, F. Pauler, A. Mckenna, J. Shendure, S. Hippenmeyer, M.S. Horwitz,
    Cell Systems 13 (2022) 438–453.e5.
date_created: 2022-06-19T22:01:57Z
date_published: 2022-06-15T00:00:00Z
date_updated: 2026-06-18T17:15:22Z
day: '15'
ddc:
- '570'
department:
- _id: SiHi
doi: 10.1016/j.cels.2022.03.006
ec_funded: 1
external_id:
  isi:
  - '000814124400002'
  pmid:
  - '35452605'
intvolume: '        13'
isi: 1
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.cels.2022.03.006
month: '06'
oa: 1
oa_version: Published Version
page: 438-453.e5
pmid: 1
project:
- _id: 260018B0-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '725780'
  name: Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development
- _id: 25D92700-B435-11E9-9278-68D0E5697425
  grant_number: LS13-002
  name: Mapping Cell-Type Specificity of the Genomic Imprintome in the Brain
publication: Cell Systems
publication_identifier:
  eissn:
  - 2405-4720
  issn:
  - 2405-4712
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Simultaneous brain cell type and lineage determined by scRNA-seq reveals stereotyped
  cortical development
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 13
year: '2022'
...
---
_id: '11417'
abstract:
- lang: eng
  text: "Over the past few years, the field of quantum information science has seen
    tremendous progress toward realizing large-scale quantum computers. With demonstrations
    of quantum computers outperforming classical computers for a select range of problems,1–3
    we have finally entered the noisy, intermediate-scale quantum (NISQ) computing
    era. While the quantum computers of today are technological marvels, they are
    not yet error corrected, and it is unclear whether any system will scale beyond
    a few hundred logical qubits without significant changes to architecture and control
    schemes. Today's quantum systems are analogous to the ENIAC (Electronic Numerical
    Integrator And Computer) and EDVAC (Electronic Discrete Variable Automatic Computer)
    systems of the 1940s, which ran on vacuum tubes. These machines were built on
    a solid, nominally scalable architecture and when they were developed, nobody
    could have predicted the development of the transistor and the impact of the resulting
    semiconductor industry. Simply put, the computers of today are nothing like the
    early computers of the 1940s. We believe that the qubits of future fault-tolerant
    quantum systems will look quite different from the qubits of the NISQ machines
    in operation today. This Special Topic issue is devoted to new and emerging quantum
    systems with a focus on enabling technologies that can eventually lead to the
    quantum analog to the transistor. We have solicited both research4–18 and perspective
    articles19–21 to discuss new and emerging qubit systems with a focus on novel
    materials, encodings, and architectures. We are proud to present a collection
    that touches on a wide range of technologies including superconductors,7–13,21
    semiconductors,15–17,19 and individual atomic qubits.18\r\n"
acknowledgement: "We would like to thank all of the authors who contributed to\r\nthis
  Special Topic. We would also like to thank the editorial team at\r\nAPL including
  Jessica Trudeau, Emma Van Burns, Martin Weides,\r\nand Lesley Cohen."
article_number: '190401'
article_processing_charge: No
article_type: letter_note
author:
- first_name: Anthony J.
  full_name: Sigillito, Anthony J.
  last_name: Sigillito
- first_name: Jacob P.
  full_name: Covey, Jacob P.
  last_name: Covey
- first_name: Johannes M
  full_name: Fink, Johannes M
  id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
  last_name: Fink
  orcid: 0000-0001-8112-028X
- first_name: Karl
  full_name: Petersson, Karl
  last_name: Petersson
- first_name: Stefan
  full_name: Preble, Stefan
  last_name: Preble
citation:
  ama: 'Sigillito AJ, Covey JP, Fink JM, Petersson K, Preble S. Emerging qubit systems:
    Guest editorial. <i>Applied Physics Letters</i>. 2022;120(19). doi:<a href="https://doi.org/10.1063/5.0097339">10.1063/5.0097339</a>'
  apa: 'Sigillito, A. J., Covey, J. P., Fink, J. M., Petersson, K., &#38; Preble,
    S. (2022). Emerging qubit systems: Guest editorial. <i>Applied Physics Letters</i>.
    American Institute of Physics. <a href="https://doi.org/10.1063/5.0097339">https://doi.org/10.1063/5.0097339</a>'
  chicago: 'Sigillito, Anthony J., Jacob P. Covey, Johannes M Fink, Karl Petersson,
    and Stefan Preble. “Emerging Qubit Systems: Guest Editorial.” <i>Applied Physics
    Letters</i>. American Institute of Physics, 2022. <a href="https://doi.org/10.1063/5.0097339">https://doi.org/10.1063/5.0097339</a>.'
  ieee: 'A. J. Sigillito, J. P. Covey, J. M. Fink, K. Petersson, and S. Preble, “Emerging
    qubit systems: Guest editorial,” <i>Applied Physics Letters</i>, vol. 120, no.
    19. American Institute of Physics, 2022.'
  ista: 'Sigillito AJ, Covey JP, Fink JM, Petersson K, Preble S. 2022. Emerging qubit
    systems: Guest editorial. Applied Physics Letters. 120(19), 190401.'
  mla: 'Sigillito, Anthony J., et al. “Emerging Qubit Systems: Guest Editorial.” <i>Applied
    Physics Letters</i>, vol. 120, no. 19, 190401, American Institute of Physics,
    2022, doi:<a href="https://doi.org/10.1063/5.0097339">10.1063/5.0097339</a>.'
  short: A.J. Sigillito, J.P. Covey, J.M. Fink, K. Petersson, S. Preble, Applied Physics
    Letters 120 (2022).
date_created: 2022-05-29T22:01:53Z
date_published: 2022-05-12T00:00:00Z
date_updated: 2026-06-18T17:14:33Z
day: '12'
ddc:
- '530'
department:
- _id: JoFi
doi: 10.1063/5.0097339
external_id:
  isi:
  - '000796002100002'
intvolume: '       120'
isi: 1
issue: '19'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1063/5.0097339
month: '05'
oa: 1
oa_version: Published Version
publication: Applied Physics Letters
publication_identifier:
  issn:
  - 0003-6951
publication_status: published
publisher: American Institute of Physics
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Emerging qubit systems: Guest editorial'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 120
year: '2022'
...
---
_id: '11356'
acknowledgement: This work was supported by the National Science Fund for Distinguished
  Young Scholars (51925101), National Key Research and Development Program of China
  (2018YFA0702100), 111 Project (B17002), and Lise Meitner Project (M2889-N).
article_processing_charge: No
article_type: letter_note
author:
- first_name: Cheng
  full_name: Chang, Cheng
  id: 9E331C2E-9F27-11E9-AE48-5033E6697425
  last_name: Chang
  orcid: 0000-0002-9515-4277
- first_name: Bingchao
  full_name: Qin, Bingchao
  last_name: Qin
- first_name: Lizhong
  full_name: Su, Lizhong
  last_name: Su
- first_name: Li Dong
  full_name: Zhao, Li Dong
  last_name: Zhao
citation:
  ama: Chang C, Qin B, Su L, Zhao LD. Distinct electron and hole transports in SnSe
    crystals. <i>Science Bulletin</i>. 2022;67(11):1105-1107. doi:<a href="https://doi.org/10.1016/j.scib.2022.04.007">10.1016/j.scib.2022.04.007</a>
  apa: Chang, C., Qin, B., Su, L., &#38; Zhao, L. D. (2022). Distinct electron and
    hole transports in SnSe crystals. <i>Science Bulletin</i>. Elsevier. <a href="https://doi.org/10.1016/j.scib.2022.04.007">https://doi.org/10.1016/j.scib.2022.04.007</a>
  chicago: Chang, Cheng, Bingchao Qin, Lizhong Su, and Li Dong Zhao. “Distinct Electron
    and Hole Transports in SnSe Crystals.” <i>Science Bulletin</i>. Elsevier, 2022.
    <a href="https://doi.org/10.1016/j.scib.2022.04.007">https://doi.org/10.1016/j.scib.2022.04.007</a>.
  ieee: C. Chang, B. Qin, L. Su, and L. D. Zhao, “Distinct electron and hole transports
    in SnSe crystals,” <i>Science Bulletin</i>, vol. 67, no. 11. Elsevier, pp. 1105–1107,
    2022.
  ista: Chang C, Qin B, Su L, Zhao LD. 2022. Distinct electron and hole transports
    in SnSe crystals. Science Bulletin. 67(11), 1105–1107.
  mla: Chang, Cheng, et al. “Distinct Electron and Hole Transports in SnSe Crystals.”
    <i>Science Bulletin</i>, vol. 67, no. 11, Elsevier, 2022, pp. 1105–07, doi:<a
    href="https://doi.org/10.1016/j.scib.2022.04.007">10.1016/j.scib.2022.04.007</a>.
  short: C. Chang, B. Qin, L. Su, L.D. Zhao, Science Bulletin 67 (2022) 1105–1107.
date_created: 2022-05-08T22:01:44Z
date_published: 2022-06-15T00:00:00Z
date_updated: 2026-06-18T10:50:26Z
day: '15'
ddc:
- '530'
department:
- _id: MaIb
doi: 10.1016/j.scib.2022.04.007
external_id:
  isi:
  - '000835291100006'
  pmid:
  - '36545972'
intvolume: '        67'
isi: 1
issue: '11'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.scib.2022.04.007
month: '06'
oa: 1
oa_version: Published Version
page: 1105-1107
pmid: 1
project:
- _id: 9B8804FC-BA93-11EA-9121-9846C619BF3A
  grant_number: M02889
  name: Bottom-up Engineering for Thermoelectric Applications
publication: Science Bulletin
publication_identifier:
  eissn:
  - 2095-9281
  issn:
  - 2095-9273
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Distinct electron and hole transports in SnSe crystals
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 67
year: '2022'
...
---
_id: '11736'
abstract:
- lang: eng
  text: "This paper introduces a methodology for inverse-modeling of yarn-level mechanics
    of cloth, based on the mechanical response of fabrics in the real world. We compiled
    a database from physical tests of several different knitted fabrics used in the
    textile industry. These data span different types of complex knit patterns, yarn
    compositions, and fabric finishes, and the results demonstrate diverse physical
    properties like stiffness, nonlinearity, and anisotropy.\r\n\r\nWe then develop
    a system for approximating these mechanical responses with yarn-level cloth simulation.
    To do so, we introduce an efficient pipeline for converting between fabric-level
    data and yarn-level simulation, including a novel swatch-level approximation for
    speeding up computation, and some small-but-necessary extensions to yarn-level
    models used in computer graphics. The dataset used for this paper can be found
    at http://mslab.es/projects/YarnLevelFabrics."
acknowledged_ssus:
- _id: ScienComp
acknowledgement: We wish to thank the anonymous reviewers for their helpful comments.
  To develop this project, we were helped by many people both at Under Armour (Clay
  Dean, Randall Harward, Kyle Blakely, Craig Simile, Michael Seiz, Brooke Malone,
  Brittainy McFarland, Emilie Phan, Lindsey Kern, Courtney Oswald, Haley Barkley,
  Bob Chin, Adam Bayer, Connie Kwok, Marielle Newman, Nick Pence, Allison Hicks, Allison
  White, Candace Rubenstein, Jeremy Stangland, Fred Fagergren, Michael Mazzoleni,
  Nathaniel Berry, Manuel Frank) and SEDDI (Gabriel Cirio, Alejandro Rodríguez, Sofía
  Dominguez, Alicia Nicas, Elena Garcés, Daniel Rodríguez, David Pascual, Manuel Godoy,
  Sergio Suja, Sergio Ruiz, Roberto Condori, Alberto Martín, Graham Sullivan). We
  also thank the members of the Visual Computing Group at IST Austria and the Multimodal
  Simulation Lab at URJC for their feedback. This research was supported by the Scientific
  Service Units (SSU) of IST Austria through resources provided by Scientific Computing,
  and it was funded in part by the European Research Council (ERC Consolidator Grant
  772738 TouchDesign).
article_number: '65'
article_processing_charge: No
article_type: original
author:
- first_name: Georg
  full_name: Sperl, Georg
  id: 4DD40360-F248-11E8-B48F-1D18A9856A87
  last_name: Sperl
- first_name: Rosa M.
  full_name: Sánchez-Banderas, Rosa M.
  last_name: Sánchez-Banderas
- first_name: Manwen
  full_name: Li, Manwen
  last_name: Li
- first_name: Christopher J
  full_name: Wojtan, Christopher J
  id: 3C61F1D2-F248-11E8-B48F-1D18A9856A87
  last_name: Wojtan
  orcid: 0000-0001-6646-5546
- first_name: Miguel A.
  full_name: Otaduy, Miguel A.
  last_name: Otaduy
citation:
  ama: Sperl G, Sánchez-Banderas RM, Li M, Wojtan C, Otaduy MA. Estimation of yarn-level
    simulation models for production fabrics. <i>ACM Transactions on Graphics</i>.
    2022;41(4). doi:<a href="https://doi.org/10.1145/3528223.3530167">10.1145/3528223.3530167</a>
  apa: Sperl, G., Sánchez-Banderas, R. M., Li, M., Wojtan, C., &#38; Otaduy, M. A.
    (2022). Estimation of yarn-level simulation models for production fabrics. <i>ACM
    Transactions on Graphics</i>. Association for Computing Machinery. <a href="https://doi.org/10.1145/3528223.3530167">https://doi.org/10.1145/3528223.3530167</a>
  chicago: Sperl, Georg, Rosa M. Sánchez-Banderas, Manwen Li, Chris Wojtan, and Miguel
    A. Otaduy. “Estimation of Yarn-Level Simulation Models for Production Fabrics.”
    <i>ACM Transactions on Graphics</i>. Association for Computing Machinery, 2022.
    <a href="https://doi.org/10.1145/3528223.3530167">https://doi.org/10.1145/3528223.3530167</a>.
  ieee: G. Sperl, R. M. Sánchez-Banderas, M. Li, C. Wojtan, and M. A. Otaduy, “Estimation
    of yarn-level simulation models for production fabrics,” <i>ACM Transactions on
    Graphics</i>, vol. 41, no. 4. Association for Computing Machinery, 2022.
  ista: Sperl G, Sánchez-Banderas RM, Li M, Wojtan C, Otaduy MA. 2022. Estimation
    of yarn-level simulation models for production fabrics. ACM Transactions on Graphics.
    41(4), 65.
  mla: Sperl, Georg, et al. “Estimation of Yarn-Level Simulation Models for Production
    Fabrics.” <i>ACM Transactions on Graphics</i>, vol. 41, no. 4, 65, Association
    for Computing Machinery, 2022, doi:<a href="https://doi.org/10.1145/3528223.3530167">10.1145/3528223.3530167</a>.
  short: G. Sperl, R.M. Sánchez-Banderas, M. Li, C. Wojtan, M.A. Otaduy, ACM Transactions
    on Graphics 41 (2022).
date_created: 2022-08-07T22:01:58Z
date_published: 2022-07-22T00:00:00Z
date_updated: 2026-06-18T17:20:41Z
day: '22'
ddc:
- '000'
department:
- _id: ChWo
doi: 10.1145/3528223.3530167
external_id:
  isi:
  - '000830989200114'
intvolume: '        41'
isi: 1
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1145/3528223.3530167
month: '07'
oa: 1
oa_version: Published Version
publication: ACM Transactions on Graphics
publication_identifier:
  eissn:
  - 1557-7368
  issn:
  - 0730-0301
publication_status: published
publisher: Association for Computing Machinery
quality_controlled: '1'
related_material:
  link:
  - description: News on the ISTA website
    relation: press_release
    url: https://ista.ac.at/en/news/digital-yarn-real-socks/
  record:
  - id: '12358'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Estimation of yarn-level simulation models for production fabrics
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 41
year: '2022'
...
