---
_id: '13147'
abstract:
- lang: eng
text: "We investigate fast and communication-efficient algorithms for the classic
problem of minimizing a sum of strongly convex and smooth functions that are distributed
among n\r\n different nodes, which can communicate using a limited number of bits.
Most previous communication-efficient approaches for this problem are limited
to first-order optimization, and therefore have \\emph{linear} dependence on the
condition number in their communication complexity. We show that this dependence
is not inherent: communication-efficient methods can in fact have sublinear dependence
on the condition number. For this, we design and analyze the first communication-efficient
distributed variants of preconditioned gradient descent for Generalized Linear
Models, and for Newton’s method. Our results rely on a new technique for quantizing
both the preconditioner and the descent direction at each step of the algorithms,
while controlling their convergence rate. We also validate our findings experimentally,
showing faster convergence and reduced communication relative to previous methods."
acknowledgement: The authors would like to thank Janne Korhonen, Aurelien Lucchi,
Celestine MendlerDunner and Antonio Orvieto for helpful discussions. FA ¨and DA
were supported during this work by the European Research Council (ERC) under the
European Union’s Horizon 2020 research and innovation programme (grant agreement
No 805223 ScaleML). PD was supported by the European Union’s Horizon 2020 programme
under the Marie Skłodowska-Curie grant agreement No. 754411.
article_processing_charge: No
arxiv: 1
author:
- first_name: Foivos
full_name: Alimisis, Foivos
last_name: Alimisis
- first_name: Peter
full_name: Davies, Peter
id: 11396234-BB50-11E9-B24C-90FCE5697425
last_name: Davies
orcid: 0000-0002-5646-9524
- first_name: Dan-Adrian
full_name: Alistarh, Dan-Adrian
id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
last_name: Alistarh
orcid: 0000-0003-3650-940X
citation:
ama: 'Alimisis F, Davies P, Alistarh D-A. Communication-efficient distributed optimization
with quantized preconditioners. In: Proceedings of the 38th International Conference
on Machine Learning. Vol 139. ML Research Press; 2021:196-206.'
apa: 'Alimisis, F., Davies, P., & Alistarh, D.-A. (2021). Communication-efficient
distributed optimization with quantized preconditioners. In Proceedings of
the 38th International Conference on Machine Learning (Vol. 139, pp. 196–206).
Virtual: ML Research Press.'
chicago: Alimisis, Foivos, Peter Davies, and Dan-Adrian Alistarh. “Communication-Efficient
Distributed Optimization with Quantized Preconditioners.” In Proceedings of
the 38th International Conference on Machine Learning, 139:196–206. ML Research
Press, 2021.
ieee: F. Alimisis, P. Davies, and D.-A. Alistarh, “Communication-efficient distributed
optimization with quantized preconditioners,” in Proceedings of the 38th International
Conference on Machine Learning, Virtual, 2021, vol. 139, pp. 196–206.
ista: 'Alimisis F, Davies P, Alistarh D-A. 2021. Communication-efficient distributed
optimization with quantized preconditioners. Proceedings of the 38th International
Conference on Machine Learning. ICML: International Conference on Machine Learning
vol. 139, 196–206.'
mla: Alimisis, Foivos, et al. “Communication-Efficient Distributed Optimization
with Quantized Preconditioners.” Proceedings of the 38th International Conference
on Machine Learning, vol. 139, ML Research Press, 2021, pp. 196–206.
short: F. Alimisis, P. Davies, D.-A. Alistarh, in:, Proceedings of the 38th International
Conference on Machine Learning, ML Research Press, 2021, pp. 196–206.
conference:
end_date: 2021-07-24
location: Virtual
name: 'ICML: International Conference on Machine Learning'
start_date: 2021-07-18
corr_author: '1'
date_created: 2023-06-18T22:00:48Z
date_published: 2021-07-01T00:00:00Z
date_updated: 2025-07-10T11:50:37Z
day: '01'
ddc:
- '000'
department:
- _id: DaAl
ec_funded: 1
external_id:
arxiv:
- '2102.07214'
file:
- access_level: open_access
checksum: 7ec0d59bac268b49c76bf2e036dedd7a
content_type: application/pdf
creator: dernst
date_created: 2023-06-19T10:41:05Z
date_updated: 2023-06-19T10:41:05Z
file_id: '13154'
file_name: 2021_PMLR_Alimisis.pdf
file_size: 429087
relation: main_file
success: 1
file_date_updated: 2023-06-19T10:41:05Z
has_accepted_license: '1'
intvolume: ' 139'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 196-206
project:
- _id: 268A44D6-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '805223'
name: Elastic Coordination for Scalable Machine Learning
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Proceedings of the 38th International Conference on Machine Learning
publication_identifier:
eissn:
- 2640-3498
isbn:
- '9781713845065'
publication_status: published
publisher: ML Research Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Communication-efficient distributed optimization with quantized preconditioners
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 139
year: '2021'
...
---
_id: '13356'
abstract:
- lang: eng
text: 'Self-assembly of nanoparticles can be mediated by polymers, but has so far
led almost exclusively to nanoparticle aggregates that are amorphous. Here, we
employed Coulombic interactions to generate a range of composite materials from
mixtures of charged nanoparticles and oppositely charged polymers. The assembly
behavior of these nanoparticle/polymer composites depends on their order of addition:
polymers added to nanoparticles give rise to stable aggregates, but nanoparticles
added to polymers disassemble the initially formed aggregates. The amorphous aggregates
were transformed into crystalline ones by transiently increasing the ionic strength
of the solution. The morphology of the resulting crystals depended on the length
of the polymer: short polymer chains mediated the self-assembly of nanoparticles
into strongly faceted crystals, whereas long chains led to pseudospherical nanoparticle/polymer
assemblies, within which the crystalline order of nanoparticles was retained.'
article_processing_charge: No
article_type: original
author:
- first_name: Tong
full_name: Bian, Tong
last_name: Bian
- first_name: Rafal
full_name: Klajn, Rafal
id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
last_name: Klajn
citation:
ama: Bian T, Klajn R. Morphology control in crystalline nanoparticle–polymer aggregates.
Annals of the New York Academy of Sciences. 2021;1505(1):191-201. doi:10.1111/nyas.14674
apa: Bian, T., & Klajn, R. (2021). Morphology control in crystalline nanoparticle–polymer
aggregates. Annals of the New York Academy of Sciences. Wiley. https://doi.org/10.1111/nyas.14674
chicago: Bian, Tong, and Rafal Klajn. “Morphology Control in Crystalline Nanoparticle–Polymer
Aggregates.” Annals of the New York Academy of Sciences. Wiley, 2021. https://doi.org/10.1111/nyas.14674.
ieee: T. Bian and R. Klajn, “Morphology control in crystalline nanoparticle–polymer
aggregates,” Annals of the New York Academy of Sciences, vol. 1505, no.
1. Wiley, pp. 191–201, 2021.
ista: Bian T, Klajn R. 2021. Morphology control in crystalline nanoparticle–polymer
aggregates. Annals of the New York Academy of Sciences. 1505(1), 191–201.
mla: Bian, Tong, and Rafal Klajn. “Morphology Control in Crystalline Nanoparticle–Polymer
Aggregates.” Annals of the New York Academy of Sciences, vol. 1505, no.
1, Wiley, 2021, pp. 191–201, doi:10.1111/nyas.14674.
short: T. Bian, R. Klajn, Annals of the New York Academy of Sciences 1505 (2021)
191–201.
date_created: 2023-08-01T09:33:39Z
date_published: 2021-12-01T00:00:00Z
date_updated: 2024-10-14T12:12:06Z
day: '01'
ddc:
- '540'
doi: 10.1111/nyas.14674
extern: '1'
external_id:
pmid:
- '34427923'
intvolume: ' 1505'
issue: '1'
keyword:
- History and Philosophy of Science
- General Biochemistry
- Genetics and Molecular Biology
- General Neuroscience
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1111/nyas.14674
month: '12'
oa: 1
oa_version: Published Version
page: 191-201
pmid: 1
publication: Annals of the New York Academy of Sciences
publication_identifier:
eissn:
- 1749-6632
issn:
- 0077-8923
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Morphology control in crystalline nanoparticle–polymer aggregates
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1505
year: '2021'
...
---
OA_place: repository
OA_type: green
_id: '19909'
abstract:
- lang: eng
text: Most water in the Universe may be superionic, and its thermodynamic and transport
properties are crucial for planetary science but difficult to probe experimentally
or theoretically. We use machine learning and free-energy methods to overcome
the limitations of quantum mechanical simulations and characterize hydrogen diffusion,
superionic transitions and phase behaviours of water at extreme conditions. We
predict that close-packed superionic phases, which have a fraction of mixed stacking
for finite systems, are stable over a wide temperature and pressure range, whereas
a body-centred cubic superionic phase is only thermodynamically stable in a small
window but is kinetically favoured. Our phase boundaries, which are consistent
with existing—albeit scarce—experimental observations, help resolve the fractions
of insulating ice, different superionic phases and liquid water inside ice giants.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Bingqing
full_name: Cheng, Bingqing
id: cbe3cda4-d82c-11eb-8dc7-8ff94289fcc9
last_name: Cheng
orcid: 0000-0002-3584-9632
- first_name: Mandy
full_name: Bethkenhagen, Mandy
last_name: Bethkenhagen
- first_name: Chris J.
full_name: Pickard, Chris J.
last_name: Pickard
- first_name: Sebastien
full_name: Hamel, Sebastien
last_name: Hamel
citation:
ama: Cheng B, Bethkenhagen M, Pickard CJ, Hamel S. Phase behaviours of superionic
water at planetary conditions. Nature Physics. 2021;17(11):1228-1232. doi:10.1038/s41567-021-01334-9
apa: Cheng, B., Bethkenhagen, M., Pickard, C. J., & Hamel, S. (2021). Phase
behaviours of superionic water at planetary conditions. Nature Physics.
Springer Nature. https://doi.org/10.1038/s41567-021-01334-9
chicago: Cheng, Bingqing, Mandy Bethkenhagen, Chris J. Pickard, and Sebastien Hamel.
“Phase Behaviours of Superionic Water at Planetary Conditions.” Nature Physics.
Springer Nature, 2021. https://doi.org/10.1038/s41567-021-01334-9.
ieee: B. Cheng, M. Bethkenhagen, C. J. Pickard, and S. Hamel, “Phase behaviours
of superionic water at planetary conditions,” Nature Physics, vol. 17,
no. 11. Springer Nature, pp. 1228–1232, 2021.
ista: Cheng B, Bethkenhagen M, Pickard CJ, Hamel S. 2021. Phase behaviours of superionic
water at planetary conditions. Nature Physics. 17(11), 1228–1232.
mla: Cheng, Bingqing, et al. “Phase Behaviours of Superionic Water at Planetary
Conditions.” Nature Physics, vol. 17, no. 11, Springer Nature, 2021, pp.
1228–32, doi:10.1038/s41567-021-01334-9.
short: B. Cheng, M. Bethkenhagen, C.J. Pickard, S. Hamel, Nature Physics 17 (2021)
1228–1232.
date_created: 2025-06-26T11:36:36Z
date_published: 2021-11-01T00:00:00Z
date_updated: 2025-06-26T11:49:07Z
day: '01'
doi: 10.1038/s41567-021-01334-9
extern: '1'
external_id:
arxiv:
- '2103.09035'
intvolume: ' 17'
issue: '11'
language:
- iso: eng
month: '11'
oa_version: Preprint
page: 1228-1232
publication: Nature Physics
publication_identifier:
eissn:
- 1745-2481
issn:
- 1745-2473
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
record:
- id: '9696'
relation: earlier_version
status: public
scopus_import: '1'
status: public
title: Phase behaviours of superionic water at planetary conditions
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2021'
...
---
OA_place: repository
OA_type: green
_id: '20619'
abstract:
- lang: eng
text: The first author’s previous work established Solomon’s WDVV-type relations
for Welschinger’s invariant curve counts in real symplectic fourfolds by lifting
geometric relations over possibly unorientable morphisms. We apply her framework
to obtain WDVV-style relations for the disk invariants of real symplectic sixfolds
with some symmetry, in particular confirming Alcolado’s prediction for P^3 and
extending it to other spaces. These relations reduce the computation of Welschinger’s
invariants of many real symplectic sixfolds to invariants in small degrees and
provide lower bounds for counts of real rational curves with positive-dimensional
insertions in some cases. In the case of P^3, our lower bounds fit perfectly with
Kollár’s vanishing results.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Xujia
full_name: Chen, Xujia
id: 968ad14a-fd86-11ee-a420-ea29715511a3
last_name: Chen
- first_name: Aleksey
full_name: Zinger, Aleksey
last_name: Zinger
citation:
ama: Chen X, Zinger A. WDVV-type relations for disk Gromov–Witten invariants in
dimension 6. Mathematische Annalen. 2021;379(3-4):1231-1313. doi:10.1007/s00208-020-02130-1
apa: Chen, X., & Zinger, A. (2021). WDVV-type relations for disk Gromov–Witten
invariants in dimension 6. Mathematische Annalen. Springer Nature. https://doi.org/10.1007/s00208-020-02130-1
chicago: Chen, Xujia, and Aleksey Zinger. “WDVV-Type Relations for Disk Gromov–Witten
Invariants in Dimension 6.” Mathematische Annalen. Springer Nature, 2021.
https://doi.org/10.1007/s00208-020-02130-1.
ieee: X. Chen and A. Zinger, “WDVV-type relations for disk Gromov–Witten invariants
in dimension 6,” Mathematische Annalen, vol. 379, no. 3–4. Springer Nature,
pp. 1231–1313, 2021.
ista: Chen X, Zinger A. 2021. WDVV-type relations for disk Gromov–Witten invariants
in dimension 6. Mathematische Annalen. 379(3–4), 1231–1313.
mla: Chen, Xujia, and Aleksey Zinger. “WDVV-Type Relations for Disk Gromov–Witten
Invariants in Dimension 6.” Mathematische Annalen, vol. 379, no. 3–4, Springer
Nature, 2021, pp. 1231–313, doi:10.1007/s00208-020-02130-1.
short: X. Chen, A. Zinger, Mathematische Annalen 379 (2021) 1231–1313.
date_created: 2025-11-10T08:41:40Z
date_published: 2021-01-25T00:00:00Z
date_updated: 2025-11-10T15:11:29Z
day: '25'
doi: 10.1007/s00208-020-02130-1
extern: '1'
external_id:
arxiv:
- '1904.04254'
intvolume: ' 379'
issue: 3-4
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.1904.04254
month: '01'
oa: 1
oa_version: Preprint
page: 1231-1313
publication: Mathematische Annalen
publication_identifier:
eissn:
- 1432-1807
issn:
- 0025-5831
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: WDVV-type relations for disk Gromov–Witten invariants in dimension 6
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 379
year: '2021'
...
---
OA_place: repository
OA_type: green
_id: '20622'
abstract:
- lang: eng
text: We first recall Solomon’s relations for Welschinger invariants counting real
curves in real symplectic fourfolds and the Witten–Dijkgraaf–Verlinde–Verlinde
(WDVV)-style relations for Welschinger invariants counting real curves in real
symplectic sixfolds with some symmetry. We then explicitly demonstrate that, in
some important cases (projective spaces with standard conjugations, real blowups
of the projective plane, and two- and threefold products of the one-dimensional
projective space with two involutions each), these relations provide complete
recursions determining all Welschinger invariants from basic input. We include
extensive tables of Welschinger invariants in low degrees obtained from these
recursions with Mathematica. These invariants provide lower bounds for counts
of real rational curves, including with curve insertions in smooth algebraic threefolds.
article_processing_charge: No
arxiv: 1
author:
- first_name: Xujia
full_name: Chen, Xujia
id: 968ad14a-fd86-11ee-a420-ea29715511a3
last_name: Chen
- first_name: Aleksey
full_name: Zinger, Aleksey
last_name: Zinger
citation:
ama: 'Chen X, Zinger A. WDVV-type relations for Welschinger’s invariants: Applications.
Kyoto Journal of Mathematics. 61(2):339-376. doi:10.1215/21562261-2021-0005'
apa: 'Chen, X., & Zinger, A. (n.d.). WDVV-type relations for Welschinger’s invariants:
Applications. Kyoto Journal of Mathematics. Duke University Press. https://doi.org/10.1215/21562261-2021-0005'
chicago: 'Chen, Xujia, and Aleksey Zinger. “WDVV-Type Relations for Welschinger’s
Invariants: Applications.” Kyoto Journal of Mathematics. Duke University
Press, n.d. https://doi.org/10.1215/21562261-2021-0005.'
ieee: 'X. Chen and A. Zinger, “WDVV-type relations for Welschinger’s invariants:
Applications,” Kyoto Journal of Mathematics, vol. 61, no. 2. Duke University
Press, pp. 339–376.'
ista: 'Chen X, Zinger A. WDVV-type relations for Welschinger’s invariants: Applications.
Kyoto Journal of Mathematics. 61(2), 339–376.'
mla: 'Chen, Xujia, and Aleksey Zinger. “WDVV-Type Relations for Welschinger’s Invariants:
Applications.” Kyoto Journal of Mathematics, vol. 61, no. 2, Duke University
Press, pp. 339–76, doi:10.1215/21562261-2021-0005.'
short: X. Chen, A. Zinger, Kyoto Journal of Mathematics 61 (n.d.) 339–376.
date_created: 2025-11-10T08:45:12Z
date_published: 2021-06-01T00:00:00Z
date_updated: 2025-11-10T15:13:58Z
day: '01'
doi: 10.1215/21562261-2021-0005
extern: '1'
external_id:
arxiv:
- '1809.08938'
intvolume: ' 61'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.1809.08938
month: '06'
oa: 1
oa_version: Preprint
page: 339-376
publication: Kyoto Journal of Mathematics
publication_identifier:
eissn:
- 2154-3321
publication_status: submitted
publisher: Duke University Press
quality_controlled: '1'
status: public
title: 'WDVV-type relations for Welschinger''s invariants: Applications'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 61
year: '2021'
...
---
OA_place: publisher
OA_type: hybrid
_id: '20765'
abstract:
- lang: eng
text: A cascade Suzuki–Miyaura cross-coupling between two non-symmetrical coupling
partners gave rise to 9,10-dihydrophenanthrenes with full site-selectivity. The
choice of base was critical to facilitate the challenging coupling of the secondary
boronate group.
article_processing_charge: No
article_type: original
author:
- first_name: Suzanne
full_name: Willems, Suzanne
last_name: Willems
- first_name: Georgios
full_name: Toupalas, Georgios
last_name: Toupalas
- first_name: Julia
full_name: Reisenbauer, Julia
id: 51d862e9-36ee-11f0-86d3-8534c85a5496
last_name: Reisenbauer
- first_name: Bill
full_name: Morandi, Bill
last_name: Morandi
citation:
ama: Willems S, Toupalas G, Reisenbauer J, Morandi B. A site-selective and stereospecific
cascade Suzuki–Miyaura annulation of alkyl 1,2-bisboronic esters and 2,2′-dihalo
1,1′-biaryls. Chemical Communications. 2021;57(32):3909-3912. doi:10.1039/d1cc00648g
apa: Willems, S., Toupalas, G., Reisenbauer, J., & Morandi, B. (2021). A site-selective
and stereospecific cascade Suzuki–Miyaura annulation of alkyl 1,2-bisboronic esters
and 2,2′-dihalo 1,1′-biaryls. Chemical Communications. Royal Society of
Chemistry. https://doi.org/10.1039/d1cc00648g
chicago: Willems, Suzanne, Georgios Toupalas, Julia Reisenbauer, and Bill Morandi.
“A Site-Selective and Stereospecific Cascade Suzuki–Miyaura Annulation of Alkyl
1,2-Bisboronic Esters and 2,2′-Dihalo 1,1′-Biaryls.” Chemical Communications.
Royal Society of Chemistry, 2021. https://doi.org/10.1039/d1cc00648g.
ieee: S. Willems, G. Toupalas, J. Reisenbauer, and B. Morandi, “A site-selective
and stereospecific cascade Suzuki–Miyaura annulation of alkyl 1,2-bisboronic esters
and 2,2′-dihalo 1,1′-biaryls,” Chemical Communications, vol. 57, no. 32.
Royal Society of Chemistry, pp. 3909–3912, 2021.
ista: Willems S, Toupalas G, Reisenbauer J, Morandi B. 2021. A site-selective and
stereospecific cascade Suzuki–Miyaura annulation of alkyl 1,2-bisboronic esters
and 2,2′-dihalo 1,1′-biaryls. Chemical Communications. 57(32), 3909–3912.
mla: Willems, Suzanne, et al. “A Site-Selective and Stereospecific Cascade Suzuki–Miyaura
Annulation of Alkyl 1,2-Bisboronic Esters and 2,2′-Dihalo 1,1′-Biaryls.” Chemical
Communications, vol. 57, no. 32, Royal Society of Chemistry, 2021, pp. 3909–12,
doi:10.1039/d1cc00648g.
short: S. Willems, G. Toupalas, J. Reisenbauer, B. Morandi, Chemical Communications
57 (2021) 3909–3912.
date_created: 2025-12-09T14:25:17Z
date_published: 2021-03-15T00:00:00Z
date_updated: 2025-12-16T12:06:53Z
day: '15'
ddc:
- '540'
doi: 10.1039/d1cc00648g
extern: '1'
external_id:
pmid:
- '33871510'
has_accepted_license: '1'
intvolume: ' 57'
issue: '32'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: "DOI\thttps://doi.org/10.1039/D1CC00648G"
month: '03'
oa: 1
oa_version: Published Version
page: 3909-3912
pmid: 1
publication: Chemical Communications
publication_identifier:
eissn:
- 1364-548X
issn:
- 1359-7345
publication_status: published
publisher: Royal Society of Chemistry
quality_controlled: '1'
scopus_import: '1'
status: public
title: A site-selective and stereospecific cascade Suzuki–Miyaura annulation of alkyl
1,2-bisboronic esters and 2,2′-dihalo 1,1′-biaryls
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/3.0/legalcode
name: Creative Commons Attribution 3.0 Unported (CC BY 3.0)
short: CC BY (3.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 57
year: '2021'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '19472'
abstract:
- lang: eng
text: The forebrain hemispheres are predominantly separated during embryogenesis
by the interhemispheric fissure (IHF). Radial astroglia remodel the IHF to form
a continuous substrate between the hemispheres for midline crossing of the corpus
callosum (CC) and hippocampal commissure (HC). Deleted in colorectal carcinoma
(DCC) and netrin 1 (NTN1) are molecules that have an evolutionarily conserved
function in commissural axon guidance. The CC and HC are absent in Dcc
and Ntn1 knockout mice, while other commissures are
only partially affected, suggesting an additional aetiology in forebrain commissure
formation. Here, we find that these molecules play a critical role in regulating
astroglial development and IHF remodelling during CC and HC formation. Human subjects
with DCC mutations display disrupted IHF remodelling
associated with CC and HC malformations. Thus, axon guidance molecules such as
DCC and NTN1 first regulate the formation of a midline substrate for dorsal commissures
prior to their role in regulating axonal growth and guidance across it.
article_number: '61769'
article_processing_charge: Yes
article_type: original
author:
- first_name: Laura
full_name: Morcom, Laura
last_name: Morcom
- first_name: Ilan
full_name: Gobius, Ilan
last_name: Gobius
- first_name: Ashley PL
full_name: Marsh, Ashley PL
last_name: Marsh
- first_name: Rodrigo
full_name: Suárez, Rodrigo
last_name: Suárez
- first_name: Jonathan WC
full_name: Lim, Jonathan WC
last_name: Lim
- first_name: Caitlin
full_name: Bridges, Caitlin
last_name: Bridges
- first_name: Yunan
full_name: Ye, Yunan
last_name: Ye
- first_name: Laura R
full_name: Fenlon, Laura R
last_name: Fenlon
- first_name: Yvrick
full_name: Zagar, Yvrick
last_name: Zagar
- first_name: Amelia May Barnett
full_name: Douglass, Amelia May Barnett
id: de5f6fda-80fb-11ef-996f-a8c4ecd8e289
last_name: Douglass
orcid: 0000-0001-5398-6473
- first_name: Amber-Lee S
full_name: Donahoo, Amber-Lee S
last_name: Donahoo
- first_name: Thomas
full_name: Fothergill, Thomas
last_name: Fothergill
- first_name: Samreen
full_name: Shaikh, Samreen
last_name: Shaikh
- first_name: Peter
full_name: Kozulin, Peter
last_name: Kozulin
- first_name: Timothy J
full_name: Edwards, Timothy J
last_name: Edwards
- first_name: Helen M
full_name: Cooper, Helen M
last_name: Cooper
- first_name: Elliott H
full_name: Sherr, Elliott H
last_name: Sherr
- first_name: Alain
full_name: Chédotal, Alain
last_name: Chédotal
- first_name: Richard J
full_name: Leventer, Richard J
last_name: Leventer
- first_name: Paul J
full_name: Lockhart, Paul J
last_name: Lockhart
- first_name: Linda J
full_name: Richards, Linda J
last_name: Richards
citation:
ama: Morcom L, Gobius I, Marsh AP, et al. DCC regulates astroglial development essential
for telencephalic morphogenesis and corpus callosum formation. eLife. 2021;10.
doi:10.7554/elife.61769
apa: Morcom, L., Gobius, I., Marsh, A. P., Suárez, R., Lim, J. W., Bridges, C.,
… Richards, L. J. (2021). DCC regulates astroglial development essential for telencephalic
morphogenesis and corpus callosum formation. ELife. eLife Sciences Publications.
https://doi.org/10.7554/elife.61769
chicago: Morcom, Laura, Ilan Gobius, Ashley PL Marsh, Rodrigo Suárez, Jonathan WC
Lim, Caitlin Bridges, Yunan Ye, et al. “DCC Regulates Astroglial Development Essential
for Telencephalic Morphogenesis and Corpus Callosum Formation.” ELife.
eLife Sciences Publications, 2021. https://doi.org/10.7554/elife.61769.
ieee: L. Morcom et al., “DCC regulates astroglial development essential for
telencephalic morphogenesis and corpus callosum formation,” eLife, vol.
10. eLife Sciences Publications, 2021.
ista: Morcom L, Gobius I, Marsh AP, Suárez R, Lim JW, Bridges C, Ye Y, Fenlon LR,
Zagar Y, Douglass AM, Donahoo A-LS, Fothergill T, Shaikh S, Kozulin P, Edwards
TJ, Cooper HM, Sherr EH, Chédotal A, Leventer RJ, Lockhart PJ, Richards LJ. 2021.
DCC regulates astroglial development essential for telencephalic morphogenesis
and corpus callosum formation. eLife. 10, 61769.
mla: Morcom, Laura, et al. “DCC Regulates Astroglial Development Essential for Telencephalic
Morphogenesis and Corpus Callosum Formation.” ELife, vol. 10, 61769, eLife
Sciences Publications, 2021, doi:10.7554/elife.61769.
short: L. Morcom, I. Gobius, A.P. Marsh, R. Suárez, J.W. Lim, C. Bridges, Y. Ye,
L.R. Fenlon, Y. Zagar, A.M. Douglass, A.-L.S. Donahoo, T. Fothergill, S. Shaikh,
P. Kozulin, T.J. Edwards, H.M. Cooper, E.H. Sherr, A. Chédotal, R.J. Leventer,
P.J. Lockhart, L.J. Richards, ELife 10 (2021).
date_created: 2025-04-03T12:29:29Z
date_published: 2021-04-19T00:00:00Z
date_updated: 2025-07-10T11:51:41Z
day: '19'
doi: 10.7554/elife.61769
extern: '1'
external_id:
pmid:
- '33871356'
has_accepted_license: '1'
intvolume: ' 10'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.7554/eLife.61769
month: '04'
oa: 1
oa_version: Published Version
pmid: 1
publication: eLife
publication_identifier:
eissn:
- 2050-084X
publication_status: published
publisher: eLife Sciences Publications
quality_controlled: '1'
scopus_import: '1'
status: public
title: DCC regulates astroglial development essential for telencephalic morphogenesis
and corpus callosum formation
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10
year: '2021'
...
---
OA_place: publisher
OA_type: hybrid
_id: '19489'
abstract:
- lang: eng
text: "Let K be a cyclic number field of odd degree over \r\n\U0001D444 with odd
narrow class number, such that 2 is inert in \U0001D43E/\U0001D444. We define
a family of number fields {\U0001D43E(\U0001D45D)}\U0001D45D, depending on K and
indexed by the rational primes p that split completely in \U0001D43E/\U0001D444,
in which p is always ramified of degree 2. Conditional on a standard conjecture
on short character sums, the density of such rational primes p that exhibit one
of two possible ramified factorizations in \U0001D43E(\U0001D45D)/\U0001D444 is
strictly between 0 and 1 and is given explicitly as a formula in terms of the
degree of the extension \U0001D43E/\U0001D444. Our results are unconditional in
the cubic case. Our proof relies on a detailed study of the joint distribution
of spins of prime ideals."
article_number: '1'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Yik Tung
full_name: Chan, Yik Tung
id: c4c0afc8-9262-11ed-9231-d8b0bc743af1
last_name: Chan
orcid: 0000-0001-8467-4106
- first_name: Christine
full_name: McMeekin, Christine
last_name: McMeekin
- first_name: Djordjo
full_name: Milovic, Djordjo
last_name: Milovic
citation:
ama: Chan S, McMeekin C, Milovic D. A density of ramified primes. Research in
Number Theory. 2021;8. doi:10.1007/s40993-021-00295-5
apa: Chan, S., McMeekin, C., & Milovic, D. (2021). A density of ramified primes.
Research in Number Theory. Springer Nature. https://doi.org/10.1007/s40993-021-00295-5
chicago: Chan, Stephanie, Christine McMeekin, and Djordjo Milovic. “A Density of
Ramified Primes.” Research in Number Theory. Springer Nature, 2021. https://doi.org/10.1007/s40993-021-00295-5.
ieee: S. Chan, C. McMeekin, and D. Milovic, “A density of ramified primes,” Research
in Number Theory, vol. 8. Springer Nature, 2021.
ista: Chan S, McMeekin C, Milovic D. 2021. A density of ramified primes. Research
in Number Theory. 8, 1.
mla: Chan, Stephanie, et al. “A Density of Ramified Primes.” Research in Number
Theory, vol. 8, 1, Springer Nature, 2021, doi:10.1007/s40993-021-00295-5.
short: S. Chan, C. McMeekin, D. Milovic, Research in Number Theory 8 (2021).
date_created: 2025-04-05T10:50:51Z
date_published: 2021-11-15T00:00:00Z
date_updated: 2025-07-10T11:51:46Z
day: '15'
ddc:
- '510'
doi: 10.1007/s40993-021-00295-5
extern: '1'
external_id:
arxiv:
- '2005.10188'
has_accepted_license: '1'
intvolume: ' 8'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1007/s40993-021-00295-5
month: '11'
oa: 1
oa_version: Published Version
publication: Research in Number Theory
publication_identifier:
eissn:
- 2363-9555
issn:
- 2522-0160
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: A density of ramified primes
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2021'
...
---
OA_place: repository
OA_type: green
_id: '19492'
abstract:
- lang: eng
text: Kuroda’s formula relates the class number of a multiquadratic number field
K to the class numbers of its quadratic subfields ki. A key component in this
formula is the unit group index (math formular). We study how Q(K) behaves on
average in certain natural families of totally real biquadratic fields K parametrized
by prime numbers.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Yik Tung
full_name: Chan, Yik Tung
id: c4c0afc8-9262-11ed-9231-d8b0bc743af1
last_name: Chan
orcid: 0000-0001-8467-4106
- first_name: Djordjo
full_name: Milovic, Djordjo
last_name: Milovic
citation:
ama: Chan S, Milovic D. Kuroda’s formula and arithmetic statistics. Mathematische
Zeitschrift. 2021;300(2):1509-1527. doi:10.1007/s00209-021-02823-6
apa: Chan, S., & Milovic, D. (2021). Kuroda’s formula and arithmetic statistics.
Mathematische Zeitschrift. Springer Nature. https://doi.org/10.1007/s00209-021-02823-6
chicago: Chan, Stephanie, and Djordjo Milovic. “Kuroda’s Formula and Arithmetic
Statistics.” Mathematische Zeitschrift. Springer Nature, 2021. https://doi.org/10.1007/s00209-021-02823-6.
ieee: S. Chan and D. Milovic, “Kuroda’s formula and arithmetic statistics,” Mathematische
Zeitschrift, vol. 300, no. 2. Springer Nature, pp. 1509–1527, 2021.
ista: Chan S, Milovic D. 2021. Kuroda’s formula and arithmetic statistics. Mathematische
Zeitschrift. 300(2), 1509–1527.
mla: Chan, Stephanie, and Djordjo Milovic. “Kuroda’s Formula and Arithmetic Statistics.”
Mathematische Zeitschrift, vol. 300, no. 2, Springer Nature, 2021, pp.
1509–27, doi:10.1007/s00209-021-02823-6.
short: S. Chan, D. Milovic, Mathematische Zeitschrift 300 (2021) 1509–1527.
date_created: 2025-04-05T10:51:04Z
date_published: 2021-08-17T00:00:00Z
date_updated: 2025-07-10T11:51:48Z
day: '17'
doi: 10.1007/s00209-021-02823-6
extern: '1'
external_id:
arxiv:
- '1905.09745'
intvolume: ' 300'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.1905.09745
month: '08'
oa: 1
oa_version: Preprint
page: 1509-1527
publication: Mathematische Zeitschrift
publication_identifier:
eissn:
- 1432-1823
issn:
- 0025-5874
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Kuroda’s formula and arithmetic statistics
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 300
year: '2021'
...
---
_id: '14800'
abstract:
- lang: eng
text: 'Research on two-dimensional (2D) materials has been explosively increasing
in last seventeen years in varying subjects including condensed matter physics,
electronic engineering, materials science, and chemistry since the mechanical
exfoliation of graphene in 2004. Starting from graphene, 2D materials now have
become a big family with numerous members and diverse categories. The unique structural
features and physicochemical properties of 2D materials make them one class of
the most appealing candidates for a wide range of potential applications. In particular,
we have seen some major breakthroughs made in the field of 2D materials in last
five years not only in developing novel synthetic methods and exploring new structures/properties
but also in identifying innovative applications and pushing forward commercialisation.
In this review, we provide a critical summary on the recent progress made in the
field of 2D materials with a particular focus on last five years. After a brief
background introduction, we first discuss the major synthetic methods for 2D materials,
including the mechanical exfoliation, liquid exfoliation, vapor phase deposition,
and wet-chemical synthesis as well as phase engineering of 2D materials belonging
to the field of phase engineering of nanomaterials (PEN). We then introduce the
superconducting/optical/magnetic properties and chirality of 2D materials along
with newly emerging magic angle 2D superlattices. Following that, the promising
applications of 2D materials in electronics, optoelectronics, catalysis, energy
storage, solar cells, biomedicine, sensors, environments, etc. are described sequentially.
Thereafter, we present the theoretic calculations and simulations of 2D materials.
Finally, after concluding the current progress, we provide some personal discussions
on the existing challenges and future outlooks in this rapidly developing field. '
article_number: '2108017'
article_processing_charge: No
article_type: review
author:
- first_name: Cheng
full_name: Chang, Cheng
id: 9E331C2E-9F27-11E9-AE48-5033E6697425
last_name: Chang
orcid: 0000-0002-9515-4277
- first_name: Wei
full_name: Chen, Wei
last_name: Chen
- first_name: Ye
full_name: Chen, Ye
last_name: Chen
- first_name: Yonghua
full_name: Chen, Yonghua
last_name: Chen
- first_name: Yu
full_name: Chen, Yu
last_name: Chen
- first_name: Feng
full_name: Ding, Feng
last_name: Ding
- first_name: Chunhai
full_name: Fan, Chunhai
last_name: Fan
- first_name: Hong Jin
full_name: Fan, Hong Jin
last_name: Fan
- first_name: Zhanxi
full_name: Fan, Zhanxi
last_name: Fan
- first_name: Cheng
full_name: Gong, Cheng
last_name: Gong
- first_name: Yongji
full_name: Gong, Yongji
last_name: Gong
- first_name: Qiyuan
full_name: He, Qiyuan
last_name: He
- first_name: Xun
full_name: Hong, Xun
last_name: Hong
- first_name: Sheng
full_name: Hu, Sheng
last_name: Hu
- first_name: Weida
full_name: Hu, Weida
last_name: Hu
- first_name: Wei
full_name: Huang, Wei
last_name: Huang
- first_name: Yuan
full_name: Huang, Yuan
last_name: Huang
- first_name: Wei
full_name: Ji, Wei
last_name: Ji
- first_name: Dehui
full_name: Li, Dehui
last_name: Li
- first_name: Lain Jong
full_name: Li, Lain Jong
last_name: Li
- first_name: Qiang
full_name: Li, Qiang
last_name: Li
- first_name: Li
full_name: Lin, Li
last_name: Lin
- first_name: Chongyi
full_name: Ling, Chongyi
last_name: Ling
- first_name: Minghua
full_name: Liu, Minghua
last_name: Liu
- first_name: 'Nan'
full_name: Liu, Nan
last_name: Liu
- first_name: Zhuang
full_name: Liu, Zhuang
last_name: Liu
- first_name: Kian Ping
full_name: Loh, Kian Ping
last_name: Loh
- first_name: Jianmin
full_name: Ma, Jianmin
last_name: Ma
- first_name: Feng
full_name: Miao, Feng
last_name: Miao
- first_name: Hailin
full_name: Peng, Hailin
last_name: Peng
- first_name: Mingfei
full_name: Shao, Mingfei
last_name: Shao
- first_name: Li
full_name: Song, Li
last_name: Song
- first_name: Shao
full_name: Su, Shao
last_name: Su
- first_name: Shuo
full_name: Sun, Shuo
last_name: Sun
- first_name: Chaoliang
full_name: Tan, Chaoliang
last_name: Tan
- first_name: Zhiyong
full_name: Tang, Zhiyong
last_name: Tang
- first_name: Dingsheng
full_name: Wang, Dingsheng
last_name: Wang
- first_name: Huan
full_name: Wang, Huan
last_name: Wang
- first_name: Jinlan
full_name: Wang, Jinlan
last_name: Wang
- first_name: Xin
full_name: Wang, Xin
last_name: Wang
- first_name: Xinran
full_name: Wang, Xinran
last_name: Wang
- first_name: Andrew T.S.
full_name: Wee, Andrew T.S.
last_name: Wee
- first_name: Zhongming
full_name: Wei, Zhongming
last_name: Wei
- first_name: Yuen
full_name: Wu, Yuen
last_name: Wu
- first_name: Zhong Shuai
full_name: Wu, Zhong Shuai
last_name: Wu
- first_name: Jie
full_name: Xiong, Jie
last_name: Xiong
- first_name: Qihua
full_name: Xiong, Qihua
last_name: Xiong
- first_name: Weigao
full_name: Xu, Weigao
last_name: Xu
- first_name: Peng
full_name: Yin, Peng
last_name: Yin
- first_name: Haibo
full_name: Zeng, Haibo
last_name: Zeng
- first_name: Zhiyuan
full_name: Zeng, Zhiyuan
last_name: Zeng
- first_name: Tianyou
full_name: Zhai, Tianyou
last_name: Zhai
- first_name: Han
full_name: Zhang, Han
last_name: Zhang
- first_name: Hui
full_name: Zhang, Hui
last_name: Zhang
- first_name: Qichun
full_name: Zhang, Qichun
last_name: Zhang
- first_name: Tierui
full_name: Zhang, Tierui
last_name: Zhang
- first_name: Xiang
full_name: Zhang, Xiang
last_name: Zhang
- first_name: Li Dong
full_name: Zhao, Li Dong
last_name: Zhao
- first_name: Meiting
full_name: Zhao, Meiting
last_name: Zhao
- first_name: Weijie
full_name: Zhao, Weijie
last_name: Zhao
- first_name: Yunxuan
full_name: Zhao, Yunxuan
last_name: Zhao
- first_name: Kai Ge
full_name: Zhou, Kai Ge
last_name: Zhou
- first_name: Xing
full_name: Zhou, Xing
last_name: Zhou
- first_name: Yu
full_name: Zhou, Yu
last_name: Zhou
- first_name: Hongwei
full_name: Zhu, Hongwei
last_name: Zhu
- first_name: Hua
full_name: Zhang, Hua
last_name: Zhang
- first_name: Zhongfan
full_name: Liu, Zhongfan
last_name: Liu
citation:
ama: Chang C, Chen W, Chen Y, et al. Recent progress on two-dimensional materials.
Acta Physico-Chimica Sinica. 2021;37(12). doi:10.3866/PKU.WHXB202108017
apa: Chang, C., Chen, W., Chen, Y., Chen, Y., Chen, Y., Ding, F., … Liu, Z. (2021).
Recent progress on two-dimensional materials. Acta Physico-Chimica Sinica.
Peking University. https://doi.org/10.3866/PKU.WHXB202108017
chicago: Chang, Cheng, Wei Chen, Ye Chen, Yonghua Chen, Yu Chen, Feng Ding, Chunhai
Fan, et al. “Recent Progress on Two-Dimensional Materials.” Acta Physico-Chimica
Sinica. Peking University, 2021. https://doi.org/10.3866/PKU.WHXB202108017.
ieee: C. Chang et al., “Recent progress on two-dimensional materials,” Acta
Physico-Chimica Sinica, vol. 37, no. 12. Peking University, 2021.
ista: Chang C, Chen W, Chen Y, Chen Y, Chen Y, Ding F, Fan C, Fan HJ, Fan Z, Gong
C, Gong Y, He Q, Hong X, Hu S, Hu W, Huang W, Huang Y, Ji W, Li D, Li LJ, Li Q,
Lin L, Ling C, Liu M, Liu N, Liu Z, Loh KP, Ma J, Miao F, Peng H, Shao M, Song
L, Su S, Sun S, Tan C, Tang Z, Wang D, Wang H, Wang J, Wang X, Wang X, Wee ATS,
Wei Z, Wu Y, Wu ZS, Xiong J, Xiong Q, Xu W, Yin P, Zeng H, Zeng Z, Zhai T, Zhang
H, Zhang H, Zhang Q, Zhang T, Zhang X, Zhao LD, Zhao M, Zhao W, Zhao Y, Zhou KG,
Zhou X, Zhou Y, Zhu H, Zhang H, Liu Z. 2021. Recent progress on two-dimensional
materials. Acta Physico-Chimica Sinica. 37(12), 2108017.
mla: Chang, Cheng, et al. “Recent Progress on Two-Dimensional Materials.” Acta
Physico-Chimica Sinica, vol. 37, no. 12, 2108017, Peking University, 2021,
doi:10.3866/PKU.WHXB202108017.
short: C. Chang, W. Chen, Y. Chen, Y. Chen, Y. Chen, F. Ding, C. Fan, H.J. Fan,
Z. Fan, C. Gong, Y. Gong, Q. He, X. Hong, S. Hu, W. Hu, W. Huang, Y. Huang, W.
Ji, D. Li, L.J. Li, Q. Li, L. Lin, C. Ling, M. Liu, N. Liu, Z. Liu, K.P. Loh,
J. Ma, F. Miao, H. Peng, M. Shao, L. Song, S. Su, S. Sun, C. Tan, Z. Tang, D.
Wang, H. Wang, J. Wang, X. Wang, X. Wang, A.T.S. Wee, Z. Wei, Y. Wu, Z.S. Wu,
J. Xiong, Q. Xiong, W. Xu, P. Yin, H. Zeng, Z. Zeng, T. Zhai, H. Zhang, H. Zhang,
Q. Zhang, T. Zhang, X. Zhang, L.D. Zhao, M. Zhao, W. Zhao, Y. Zhao, K.G. Zhou,
X. Zhou, Y. Zhou, H. Zhu, H. Zhang, Z. Liu, Acta Physico-Chimica Sinica 37 (2021).
date_created: 2024-01-14T23:00:58Z
date_published: 2021-10-13T00:00:00Z
date_updated: 2025-09-10T10:12:25Z
day: '13'
department:
- _id: MaIb
doi: 10.3866/PKU.WHXB202108017
external_id:
isi:
- '000731879300002'
intvolume: ' 37'
isi: 1
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.3866/PKU.WHXB202108017
month: '10'
oa: 1
oa_version: Submitted Version
publication: Acta Physico-Chimica Sinica
publication_identifier:
issn:
- 1001-4861
publication_status: published
publisher: Peking University
quality_controlled: '1'
scopus_import: '1'
status: public
title: Recent progress on two-dimensional materials
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 37
year: '2021'
...
---
_id: '14889'
abstract:
- lang: eng
text: We consider the Fröhlich Hamiltonian with large coupling constant α. For initial
data of Pekar product form with coherent phonon field and with the electron minimizing
the corresponding energy, we provide a norm approximation of the evolution, valid
up to times of order α2. The approximation is given in terms of a Pekar product
state, evolved through the Landau-Pekar equations, corrected by a Bogoliubov dynamics
taking quantum fluctuations into account. This allows us to show that the Landau-Pekar
equations approximately describe the evolution of the electron- and one-phonon
reduced density matrices under the Fröhlich dynamics up to times of order α2.
acknowledgement: "Financial support by the European Union’s Horizon 2020 research
and innovation programme\r\nunder the Marie Skłodowska-Curie grant agreement No.
754411 (S.R.) and the European\r\nResearch Council under grant agreement No. 694227
(N.L. and R.S.), as well as by the SNSF\r\nEccellenza project PCEFP2 181153 (N.L.),
the NCCR SwissMAP (N.L. and B.S.) and by the\r\nDeutsche Forschungsgemeinschaft
(DFG) through the Research Training Group 1838: Spectral\r\nTheory and Dynamics
of Quantum Systems (D.M.) is gratefully acknowledged. B.S. gratefully\r\nacknowledges
financial support from the Swiss National Science Foundation through the Grant\r\n“Dynamical
and energetic properties of Bose-Einstein condensates” and from the European\r\nResearch
Council through the ERC-AdG CLaQS (grant agreement No 834782). D.M. thanks\r\nMarcel
Griesemer for helpful discussions."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Nikolai K
full_name: Leopold, Nikolai K
id: 4BC40BEC-F248-11E8-B48F-1D18A9856A87
last_name: Leopold
orcid: 0000-0002-0495-6822
- first_name: David Johannes
full_name: Mitrouskas, David Johannes
id: cbddacee-2b11-11eb-a02e-a2e14d04e52d
last_name: Mitrouskas
- first_name: Simone Anna Elvira
full_name: Rademacher, Simone Anna Elvira
id: 856966FE-A408-11E9-977E-802DE6697425
last_name: Rademacher
orcid: 0000-0001-5059-4466
- first_name: Benjamin
full_name: Schlein, Benjamin
last_name: Schlein
- first_name: Robert
full_name: Seiringer, Robert
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: Leopold NK, Mitrouskas DJ, Rademacher SAE, Schlein B, Seiringer R. Landau–Pekar
equations and quantum fluctuations for the dynamics of a strongly coupled polaron.
Pure and Applied Analysis. 2021;3(4):653-676. doi:10.2140/paa.2021.3.653
apa: Leopold, N. K., Mitrouskas, D. J., Rademacher, S. A. E., Schlein, B., &
Seiringer, R. (2021). Landau–Pekar equations and quantum fluctuations for the
dynamics of a strongly coupled polaron. Pure and Applied Analysis. Mathematical
Sciences Publishers. https://doi.org/10.2140/paa.2021.3.653
chicago: Leopold, Nikolai K, David Johannes Mitrouskas, Simone Anna Elvira Rademacher,
Benjamin Schlein, and Robert Seiringer. “Landau–Pekar Equations and Quantum Fluctuations
for the Dynamics of a Strongly Coupled Polaron.” Pure and Applied Analysis.
Mathematical Sciences Publishers, 2021. https://doi.org/10.2140/paa.2021.3.653.
ieee: N. K. Leopold, D. J. Mitrouskas, S. A. E. Rademacher, B. Schlein, and R. Seiringer,
“Landau–Pekar equations and quantum fluctuations for the dynamics of a strongly
coupled polaron,” Pure and Applied Analysis, vol. 3, no. 4. Mathematical
Sciences Publishers, pp. 653–676, 2021.
ista: Leopold NK, Mitrouskas DJ, Rademacher SAE, Schlein B, Seiringer R. 2021. Landau–Pekar
equations and quantum fluctuations for the dynamics of a strongly coupled polaron.
Pure and Applied Analysis. 3(4), 653–676.
mla: Leopold, Nikolai K., et al. “Landau–Pekar Equations and Quantum Fluctuations
for the Dynamics of a Strongly Coupled Polaron.” Pure and Applied Analysis,
vol. 3, no. 4, Mathematical Sciences Publishers, 2021, pp. 653–76, doi:10.2140/paa.2021.3.653.
short: N.K. Leopold, D.J. Mitrouskas, S.A.E. Rademacher, B. Schlein, R. Seiringer,
Pure and Applied Analysis 3 (2021) 653–676.
corr_author: '1'
date_created: 2024-01-28T23:01:43Z
date_published: 2021-10-01T00:00:00Z
date_updated: 2025-04-14T07:27:00Z
day: '01'
department:
- _id: RoSe
doi: 10.2140/paa.2021.3.653
ec_funded: 1
external_id:
arxiv:
- '2005.02098'
intvolume: ' 3'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2005.02098
month: '10'
oa: 1
oa_version: Preprint
page: 653-676
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
- _id: 25C6DC12-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '694227'
name: Analysis of quantum many-body systems
publication: Pure and Applied Analysis
publication_identifier:
eissn:
- 2578-5885
issn:
- 2578-5893
publication_status: published
publisher: Mathematical Sciences Publishers
quality_controlled: '1'
scopus_import: '1'
status: public
title: Landau–Pekar equations and quantum fluctuations for the dynamics of a strongly
coupled polaron
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 3
year: '2021'
...
---
_id: '14890'
abstract:
- lang: eng
text: We consider a system of N interacting bosons in the mean-field scaling regime
and construct corrections to the Bogoliubov dynamics that approximate the true
N-body dynamics in norm to arbitrary precision. The N-independent corrections
are given in terms of the solutions of the Bogoliubov and Hartree equations and
satisfy a generalized form of Wick's theorem. We determine the n-point correlation
functions of the excitations around the condensate, as well as the reduced densities
of the N-body system, to arbitrary accuracy, given only the knowledge of the two-point
functions of a quasi-free state and the solution of the Hartree equation. In this
way, the complex problem of computing all n-point correlation functions for an
interacting N-body system is essentially reduced to the problem of solving the
Hartree equation and the PDEs for the Bogoliubov two-point functions.
acknowledgement: "We are grateful for the hospitality of Central China Normal University
(CCNU),\r\nwhere parts of this work were done, and thank Phan Th`anh Nam, Simone\r\nRademacher,
Robert Seiringer and Stefan Teufel for helpful discussions. L.B. gratefully acknowledges
the support by the German Research Foundation (DFG) within the Research\r\nTraining
Group 1838 “Spectral Theory and Dynamics of Quantum Systems”, and the funding\r\nfrom
the European Union’s Horizon 2020 research and innovation programme under the Marie\r\nSk
lodowska-Curie Grant Agreement No. 754411."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Lea
full_name: Bossmann, Lea
id: A2E3BCBE-5FCC-11E9-AA4B-76F3E5697425
last_name: Bossmann
orcid: 0000-0002-6854-1343
- first_name: Sören P
full_name: Petrat, Sören P
id: 40AC02DC-F248-11E8-B48F-1D18A9856A87
last_name: Petrat
orcid: 0000-0002-9166-5889
- first_name: Peter
full_name: Pickl, Peter
last_name: Pickl
- first_name: Avy
full_name: Soffer, Avy
last_name: Soffer
citation:
ama: Bossmann L, Petrat SP, Pickl P, Soffer A. Beyond Bogoliubov dynamics. Pure
and Applied Analysis. 2021;3(4):677-726. doi:10.2140/paa.2021.3.677
apa: Bossmann, L., Petrat, S. P., Pickl, P., & Soffer, A. (2021). Beyond Bogoliubov
dynamics. Pure and Applied Analysis. Mathematical Sciences Publishers.
https://doi.org/10.2140/paa.2021.3.677
chicago: Bossmann, Lea, Sören P Petrat, Peter Pickl, and Avy Soffer. “Beyond Bogoliubov
Dynamics.” Pure and Applied Analysis. Mathematical Sciences Publishers,
2021. https://doi.org/10.2140/paa.2021.3.677.
ieee: L. Bossmann, S. P. Petrat, P. Pickl, and A. Soffer, “Beyond Bogoliubov dynamics,”
Pure and Applied Analysis, vol. 3, no. 4. Mathematical Sciences Publishers,
pp. 677–726, 2021.
ista: Bossmann L, Petrat SP, Pickl P, Soffer A. 2021. Beyond Bogoliubov dynamics.
Pure and Applied Analysis. 3(4), 677–726.
mla: Bossmann, Lea, et al. “Beyond Bogoliubov Dynamics.” Pure and Applied Analysis,
vol. 3, no. 4, Mathematical Sciences Publishers, 2021, pp. 677–726, doi:10.2140/paa.2021.3.677.
short: L. Bossmann, S.P. Petrat, P. Pickl, A. Soffer, Pure and Applied Analysis
3 (2021) 677–726.
corr_author: '1'
date_created: 2024-01-28T23:01:43Z
date_published: 2021-10-01T00:00:00Z
date_updated: 2025-04-14T07:44:02Z
day: '01'
department:
- _id: RoSe
doi: 10.2140/paa.2021.3.677
ec_funded: 1
external_id:
arxiv:
- '1912.11004'
intvolume: ' 3'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.1912.11004
month: '10'
oa: 1
oa_version: Preprint
page: 677-726
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Pure and Applied Analysis
publication_identifier:
eissn:
- 2578-5885
issn:
- 2578-5893
publication_status: published
publisher: Mathematical Sciences Publishers
quality_controlled: '1'
scopus_import: '1'
status: public
title: Beyond Bogoliubov dynamics
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 3
year: '2021'
...
---
_id: '14984'
abstract:
- lang: eng
text: Hybrid zones are narrow geographic regions where different populations, races
or interbreeding species meet and mate, producing mixed ‘hybrid’ offspring. They
are relatively common and can be found in a diverse range of organisms and environments.
The study of hybrid zones has played an important role in our understanding of
the origin of species, with hybrid zones having been described as ‘natural laboratories’.
This is because they allow us to study,in situ, the conditions and evolutionary
forces that enable divergent taxa to remain distinct despite some ongoing gene
exchange between them.
article_processing_charge: No
author:
- first_name: Sean
full_name: Stankowski, Sean
id: 43161670-5719-11EA-8025-FABC3DDC885E
last_name: Stankowski
- first_name: Daria
full_name: Shipilina, Daria
id: 428A94B0-F248-11E8-B48F-1D18A9856A87
last_name: Shipilina
orcid: 0000-0002-1145-9226
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
citation:
ama: 'Stankowski S, Shipilina D, Westram AM. Hybrid Zones. In: Encyclopedia of
Life Sciences. Vol 2. eLS. Wiley; 2021. doi:10.1002/9780470015902.a0029355'
apa: Stankowski, S., Shipilina, D., & Westram, A. M. (2021). Hybrid Zones. In
Encyclopedia of Life Sciences (Vol. 2). Wiley. https://doi.org/10.1002/9780470015902.a0029355
chicago: Stankowski, Sean, Daria Shipilina, and Anja M Westram. “Hybrid Zones.”
In Encyclopedia of Life Sciences, Vol. 2. ELS. Wiley, 2021. https://doi.org/10.1002/9780470015902.a0029355.
ieee: S. Stankowski, D. Shipilina, and A. M. Westram, “Hybrid Zones,” in Encyclopedia
of Life Sciences, vol. 2, Wiley, 2021.
ista: 'Stankowski S, Shipilina D, Westram AM. 2021.Hybrid Zones. In: Encyclopedia
of Life Sciences. vol. 2.'
mla: Stankowski, Sean, et al. “Hybrid Zones.” Encyclopedia of Life Sciences,
vol. 2, Wiley, 2021, doi:10.1002/9780470015902.a0029355.
short: S. Stankowski, D. Shipilina, A.M. Westram, in:, Encyclopedia of Life Sciences,
Wiley, 2021.
corr_author: '1'
date_created: 2024-02-14T12:05:50Z
date_published: 2021-05-28T00:00:00Z
date_updated: 2024-10-09T21:08:11Z
day: '28'
department:
- _id: NiBa
doi: 10.1002/9780470015902.a0029355
intvolume: ' 2'
language:
- iso: eng
month: '05'
oa_version: None
publication: Encyclopedia of Life Sciences
publication_identifier:
eisbn:
- '9780470015902'
isbn:
- '9780470016176'
publication_status: published
publisher: Wiley
quality_controlled: '1'
series_title: eLS
status: public
title: Hybrid Zones
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2
year: '2021'
...
---
_id: '14987'
abstract:
- lang: eng
text: "The goal of zero-shot learning is to construct a classifier that can identify
object classes for which no training examples are available. When training data
for some of the object classes is available but not for others, the name generalized
zero-shot learning is commonly used.\r\nIn a wider sense, the phrase zero-shot
is also used to describe other machine learning-based approaches that require
no training data from the problem of interest, such as zero-shot action recognition
or zero-shot machine translation."
article_processing_charge: No
author:
- first_name: Christoph
full_name: Lampert, Christoph
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
citation:
ama: 'Lampert C. Zero-Shot Learning. In: Ikeuchi K, ed. Computer Vision.
2nd ed. Cham: Springer; 2021:1395-1397. doi:10.1007/978-3-030-63416-2_874'
apa: 'Lampert, C. (2021). Zero-Shot Learning. In K. Ikeuchi (Ed.), Computer Vision
(2nd ed., pp. 1395–1397). Cham: Springer. https://doi.org/10.1007/978-3-030-63416-2_874'
chicago: 'Lampert, Christoph. “Zero-Shot Learning.” In Computer Vision, edited
by Katsushi Ikeuchi, 2nd ed., 1395–97. Cham: Springer, 2021. https://doi.org/10.1007/978-3-030-63416-2_874.'
ieee: 'C. Lampert, “Zero-Shot Learning,” in Computer Vision, 2nd ed., K.
Ikeuchi, Ed. Cham: Springer, 2021, pp. 1395–1397.'
ista: 'Lampert C. 2021.Zero-Shot Learning. In: Computer Vision. , 1395–1397.'
mla: Lampert, Christoph. “Zero-Shot Learning.” Computer Vision, edited by
Katsushi Ikeuchi, 2nd ed., Springer, 2021, pp. 1395–97, doi:10.1007/978-3-030-63416-2_874.
short: C. Lampert, in:, K. Ikeuchi (Ed.), Computer Vision, 2nd ed., Springer, Cham,
2021, pp. 1395–1397.
corr_author: '1'
date_created: 2024-02-14T14:05:32Z
date_published: 2021-10-13T00:00:00Z
date_updated: 2024-10-09T21:08:12Z
day: '13'
department:
- _id: ChLa
doi: 10.1007/978-3-030-63416-2_874
edition: '2'
editor:
- first_name: Katsushi
full_name: Ikeuchi, Katsushi
last_name: Ikeuchi
language:
- iso: eng
month: '10'
oa_version: None
page: 1395-1397
place: Cham
publication: Computer Vision
publication_identifier:
eisbn:
- '9783030634162'
isbn:
- '9783030634155'
publication_status: published
publisher: Springer
quality_controlled: '1'
status: public
title: Zero-Shot Learning
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2021'
...
---
_id: '14988'
abstract:
- lang: eng
text: Raw data generated from the publication - The TPLATE complex mediates membrane
bending during plant clathrin-mediated endocytosis by Johnson et al., 2021 In
PNAS
article_processing_charge: No
author:
- first_name: Alexander J
full_name: Johnson, Alexander J
id: 46A62C3A-F248-11E8-B48F-1D18A9856A87
last_name: Johnson
orcid: 0000-0002-2739-8843
citation:
ama: Johnson AJ. Raw data from Johnson et al, PNAS, 2021. 2021. doi:10.5281/ZENODO.5747100
apa: Johnson, A. J. (2021). Raw data from Johnson et al, PNAS, 2021. Zenodo. https://doi.org/10.5281/ZENODO.5747100
chicago: Johnson, Alexander J. “Raw Data from Johnson et Al, PNAS, 2021.” Zenodo,
2021. https://doi.org/10.5281/ZENODO.5747100.
ieee: A. J. Johnson, “Raw data from Johnson et al, PNAS, 2021.” Zenodo, 2021.
ista: Johnson AJ. 2021. Raw data from Johnson et al, PNAS, 2021, Zenodo, 10.5281/ZENODO.5747100.
mla: Johnson, Alexander J. Raw Data from Johnson et Al, PNAS, 2021. Zenodo,
2021, doi:10.5281/ZENODO.5747100.
short: A.J. Johnson, (2021).
corr_author: '1'
date_created: 2024-02-14T14:13:48Z
date_published: 2021-12-01T00:00:00Z
date_updated: 2025-05-14T09:25:33Z
day: '01'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.5281/ZENODO.5747100
has_accepted_license: '1'
main_file_link:
- open_access: '1'
url: https://doi.org/10.5281/zenodo.5747100
month: '12'
oa: 1
oa_version: Published Version
publisher: Zenodo
related_material:
record:
- id: '9887'
relation: used_in_publication
status: public
status: public
title: Raw data from Johnson et al, PNAS, 2021
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2021'
...
---
_id: '15013'
abstract:
- lang: eng
text: We consider random n×n matrices X with independent and centered entries and
a general variance profile. We show that the spectral radius of X converges with
very high probability to the square root of the spectral radius of the variance
matrix of X when n tends to infinity. We also establish the optimal rate of convergence,
that is a new result even for general i.i.d. matrices beyond the explicitly solvable
Gaussian cases. The main ingredient is the proof of the local inhomogeneous circular
law [arXiv:1612.07776] at the spectral edge.
acknowledgement: Partially supported by ERC Starting Grant RandMat No. 715539 and
the SwissMap grant of Swiss National Science Foundation. Partially supported by
ERC Advanced Grant RanMat No. 338804. Partially supported by the Hausdorff Center
for Mathematics in Bonn.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Johannes
full_name: Alt, Johannes
id: 36D3D8B6-F248-11E8-B48F-1D18A9856A87
last_name: Alt
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Torben H
full_name: Krüger, Torben H
id: 3020C786-F248-11E8-B48F-1D18A9856A87
last_name: Krüger
orcid: 0000-0002-4821-3297
citation:
ama: Alt J, Erdös L, Krüger TH. Spectral radius of random matrices with independent
entries. Probability and Mathematical Physics. 2021;2(2):221-280. doi:10.2140/pmp.2021.2.221
apa: Alt, J., Erdös, L., & Krüger, T. H. (2021). Spectral radius of random matrices
with independent entries. Probability and Mathematical Physics. Mathematical
Sciences Publishers. https://doi.org/10.2140/pmp.2021.2.221
chicago: Alt, Johannes, László Erdös, and Torben H Krüger. “Spectral Radius of Random
Matrices with Independent Entries.” Probability and Mathematical Physics.
Mathematical Sciences Publishers, 2021. https://doi.org/10.2140/pmp.2021.2.221.
ieee: J. Alt, L. Erdös, and T. H. Krüger, “Spectral radius of random matrices with
independent entries,” Probability and Mathematical Physics, vol. 2, no.
2. Mathematical Sciences Publishers, pp. 221–280, 2021.
ista: Alt J, Erdös L, Krüger TH. 2021. Spectral radius of random matrices with independent
entries. Probability and Mathematical Physics. 2(2), 221–280.
mla: Alt, Johannes, et al. “Spectral Radius of Random Matrices with Independent
Entries.” Probability and Mathematical Physics, vol. 2, no. 2, Mathematical
Sciences Publishers, 2021, pp. 221–80, doi:10.2140/pmp.2021.2.221.
short: J. Alt, L. Erdös, T.H. Krüger, Probability and Mathematical Physics 2 (2021)
221–280.
corr_author: '1'
date_created: 2024-02-18T23:01:03Z
date_published: 2021-05-21T00:00:00Z
date_updated: 2025-04-15T08:05:02Z
day: '21'
department:
- _id: LaEr
doi: 10.2140/pmp.2021.2.221
ec_funded: 1
external_id:
arxiv:
- '1907.13631'
intvolume: ' 2'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.1907.13631
month: '05'
oa: 1
oa_version: Preprint
page: 221-280
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '338804'
name: Random matrices, universality and disordered quantum systems
publication: Probability and Mathematical Physics
publication_identifier:
eissn:
- 2690-1005
issn:
- 2690-0998
publication_status: published
publisher: Mathematical Sciences Publishers
quality_controlled: '1'
scopus_import: '1'
status: public
title: Spectral radius of random matrices with independent entries
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2
year: '2021'
...
---
_id: '15137'
abstract:
- lang: eng
text: Characteristic properties of type III CRISPR-Cas systems include recognition
of target RNA and the subsequent induction of a multifaceted immune response.
This involves sequence-specific cleavage of the target RNA and production of cyclic
oligoadenylate (cOA) molecules. Here we report that an exposed seed region at
the 3′ end of the crRNA is essential for target RNA binding and cleavage, whereas
cOA production requires base pairing at the 5′ end of the crRNA. Moreover, we
uncover that the variation in the size and composition of type III complexes within
a single host results in variable seed regions. This may prevent escape by invading
genetic elements, while controlling cOA production tightly to prevent unnecessary
damage to the host. Lastly, we use these findings to develop a new diagnostic
tool, SCOPE, for the specific detection of SARS-CoV-2 from human nasal swab samples,
revealing sensitivities in the atto-molar range.
article_number: '5033'
article_processing_charge: Yes
article_type: original
author:
- first_name: Jurre A.
full_name: Steens, Jurre A.
last_name: Steens
- first_name: Yifan
full_name: Zhu, Yifan
last_name: Zhu
- first_name: David W.
full_name: Taylor, David W.
last_name: Taylor
- first_name: Jack Peter Kelly
full_name: Bravo, Jack Peter Kelly
id: 96aecfa5-8931-11ee-af30-aa6a5d6eee0e
last_name: Bravo
orcid: 0000-0003-0456-0753
- first_name: Stijn H. P.
full_name: Prinsen, Stijn H. P.
last_name: Prinsen
- first_name: Cor D.
full_name: Schoen, Cor D.
last_name: Schoen
- first_name: Bart J. F.
full_name: Keijser, Bart J. F.
last_name: Keijser
- first_name: Michel
full_name: Ossendrijver, Michel
last_name: Ossendrijver
- first_name: L. Marije
full_name: Hofstra, L. Marije
last_name: Hofstra
- first_name: Stan J. J.
full_name: Brouns, Stan J. J.
last_name: Brouns
- first_name: Akeo
full_name: Shinkai, Akeo
last_name: Shinkai
- first_name: John
full_name: van der Oost, John
last_name: van der Oost
- first_name: Raymond H. J.
full_name: Staals, Raymond H. J.
last_name: Staals
citation:
ama: Steens JA, Zhu Y, Taylor DW, et al. SCOPE enables type III CRISPR-Cas diagnostics
using flexible targeting and stringent CARF ribonuclease activation. Nature
Communications. 2021;12. doi:10.1038/s41467-021-25337-5
apa: Steens, J. A., Zhu, Y., Taylor, D. W., Bravo, J. P. K., Prinsen, S. H. P.,
Schoen, C. D., … Staals, R. H. J. (2021). SCOPE enables type III CRISPR-Cas diagnostics
using flexible targeting and stringent CARF ribonuclease activation. Nature
Communications. Springer Nature. https://doi.org/10.1038/s41467-021-25337-5
chicago: Steens, Jurre A., Yifan Zhu, David W. Taylor, Jack Peter Kelly Bravo, Stijn
H. P. Prinsen, Cor D. Schoen, Bart J. F. Keijser, et al. “SCOPE Enables Type III
CRISPR-Cas Diagnostics Using Flexible Targeting and Stringent CARF Ribonuclease
Activation.” Nature Communications. Springer Nature, 2021. https://doi.org/10.1038/s41467-021-25337-5.
ieee: J. A. Steens et al., “SCOPE enables type III CRISPR-Cas diagnostics
using flexible targeting and stringent CARF ribonuclease activation,” Nature
Communications, vol. 12. Springer Nature, 2021.
ista: Steens JA, Zhu Y, Taylor DW, Bravo JPK, Prinsen SHP, Schoen CD, Keijser BJF,
Ossendrijver M, Hofstra LM, Brouns SJJ, Shinkai A, van der Oost J, Staals RHJ.
2021. SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and
stringent CARF ribonuclease activation. Nature Communications. 12, 5033.
mla: Steens, Jurre A., et al. “SCOPE Enables Type III CRISPR-Cas Diagnostics Using
Flexible Targeting and Stringent CARF Ribonuclease Activation.” Nature Communications,
vol. 12, 5033, Springer Nature, 2021, doi:10.1038/s41467-021-25337-5.
short: J.A. Steens, Y. Zhu, D.W. Taylor, J.P.K. Bravo, S.H.P. Prinsen, C.D. Schoen,
B.J.F. Keijser, M. Ossendrijver, L.M. Hofstra, S.J.J. Brouns, A. Shinkai, J. van
der Oost, R.H.J. Staals, Nature Communications 12 (2021).
date_created: 2024-03-20T10:42:33Z
date_published: 2021-08-19T00:00:00Z
date_updated: 2024-06-04T06:11:54Z
day: '19'
doi: 10.1038/s41467-021-25337-5
extern: '1'
external_id:
pmid:
- '34413302'
intvolume: ' 12'
keyword:
- General Physics and Astronomy
- General Biochemistry
- Genetics and Molecular Biology
- General Chemistry
- Multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1038/s41467-021-25337-5
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Communications
publication_identifier:
issn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and
stringent CARF ribonuclease activation
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2021'
...
---
_id: '15138'
abstract:
- lang: eng
text: RNA viruses induce the formation of subcellular organelles that provide microenvironments
conducive to their replication. Here we show that replication factories of rotaviruses
represent protein‐RNA condensates that are formed via liquid–liquid phase separation
of the viroplasm‐forming proteins NSP5 and rotavirus RNA chaperone NSP2. Upon
mixing, these proteins readily form condensates at physiologically relevant low
micromolar concentrations achieved in the cytoplasm of virus‐infected cells. Early
infection stage condensates could be reversibly dissolved by 1,6‐hexanediol, as
well as propylene glycol that released rotavirus transcripts from these condensates.
During the early stages of infection, propylene glycol treatments reduced viral
replication and phosphorylation of the condensate‐forming protein NSP5. During
late infection, these condensates exhibited altered material properties and became
resistant to propylene glycol, coinciding with hyperphosphorylation of NSP5. Some
aspects of the assembly of cytoplasmic rotavirus replication factories mirror
the formation of other ribonucleoprotein granules. Such viral RNA‐rich condensates
that support replication of multi‐segmented genomes represent an attractive target
for developing novel therapeutic approaches.
article_number: e107711
article_processing_charge: Yes
article_type: original
author:
- first_name: Florian
full_name: Geiger, Florian
last_name: Geiger
- first_name: Julia
full_name: Acker, Julia
last_name: Acker
- first_name: Guido
full_name: Papa, Guido
last_name: Papa
- first_name: Xinyu
full_name: Wang, Xinyu
last_name: Wang
- first_name: William E
full_name: Arter, William E
last_name: Arter
- first_name: Kadi L
full_name: Saar, Kadi L
last_name: Saar
- first_name: Nadia A
full_name: Erkamp, Nadia A
last_name: Erkamp
- first_name: Runzhang
full_name: Qi, Runzhang
last_name: Qi
- first_name: Jack Peter Kelly
full_name: Bravo, Jack Peter Kelly
id: 96aecfa5-8931-11ee-af30-aa6a5d6eee0e
last_name: Bravo
orcid: 0000-0003-0456-0753
- first_name: Sebastian
full_name: Strauss, Sebastian
last_name: Strauss
- first_name: Georg
full_name: Krainer, Georg
last_name: Krainer
- first_name: Oscar R
full_name: Burrone, Oscar R
last_name: Burrone
- first_name: Ralf
full_name: Jungmann, Ralf
last_name: Jungmann
- first_name: Tuomas PJ
full_name: Knowles, Tuomas PJ
last_name: Knowles
- first_name: Hanna
full_name: Engelke, Hanna
last_name: Engelke
- first_name: Alexander
full_name: Borodavka, Alexander
last_name: Borodavka
citation:
ama: Geiger F, Acker J, Papa G, et al. Liquid–liquid phase separation underpins
the formation of replication factories in rotaviruses. The EMBO Journal.
2021;40(21). doi:10.15252/embj.2021107711
apa: Geiger, F., Acker, J., Papa, G., Wang, X., Arter, W. E., Saar, K. L., … Borodavka,
A. (2021). Liquid–liquid phase separation underpins the formation of replication
factories in rotaviruses. The EMBO Journal. Embo Press. https://doi.org/10.15252/embj.2021107711
chicago: Geiger, Florian, Julia Acker, Guido Papa, Xinyu Wang, William E Arter,
Kadi L Saar, Nadia A Erkamp, et al. “Liquid–Liquid Phase Separation Underpins
the Formation of Replication Factories in Rotaviruses.” The EMBO Journal.
Embo Press, 2021. https://doi.org/10.15252/embj.2021107711.
ieee: F. Geiger et al., “Liquid–liquid phase separation underpins the formation
of replication factories in rotaviruses,” The EMBO Journal, vol. 40, no.
21. Embo Press, 2021.
ista: Geiger F, Acker J, Papa G, Wang X, Arter WE, Saar KL, Erkamp NA, Qi R, Bravo
JPK, Strauss S, Krainer G, Burrone OR, Jungmann R, Knowles TP, Engelke H, Borodavka
A. 2021. Liquid–liquid phase separation underpins the formation of replication
factories in rotaviruses. The EMBO Journal. 40(21), e107711.
mla: Geiger, Florian, et al. “Liquid–Liquid Phase Separation Underpins the Formation
of Replication Factories in Rotaviruses.” The EMBO Journal, vol. 40, no.
21, e107711, Embo Press, 2021, doi:10.15252/embj.2021107711.
short: F. Geiger, J. Acker, G. Papa, X. Wang, W.E. Arter, K.L. Saar, N.A. Erkamp,
R. Qi, J.P.K. Bravo, S. Strauss, G. Krainer, O.R. Burrone, R. Jungmann, T.P. Knowles,
H. Engelke, A. Borodavka, The EMBO Journal 40 (2021).
date_created: 2024-03-20T10:42:39Z
date_published: 2021-11-02T00:00:00Z
date_updated: 2024-06-04T06:08:16Z
day: '02'
doi: 10.15252/embj.2021107711
extern: '1'
external_id:
pmid:
- '34524703'
intvolume: ' 40'
issue: '21'
keyword:
- General Immunology and Microbiology
- General Biochemistry
- Genetics and Molecular Biology
- Molecular Biology
- General Neuroscience
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.15252/embj.2021107711
month: '11'
oa: 1
oa_version: Published Version
pmid: 1
publication: The EMBO Journal
publication_identifier:
eissn:
- 1460-2075
issn:
- 0261-4189
publication_status: published
publisher: Embo Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Liquid–liquid phase separation underpins the formation of replication factories
in rotaviruses
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 40
year: '2021'
...
---
_id: '15139'
abstract:
- lang: eng
text: Rotavirus genomes are distributed between 11 distinct RNA molecules, all of
which must be selectively copackaged during virus assembly. This likely occurs
through sequence-specific RNA interactions facilitated by the RNA chaperone NSP2.
Here, we report that NSP2 autoregulates its chaperone activity through its C-terminal
region (CTR) that promotes RNA–RNA interactions by limiting its helix-unwinding
activity. Unexpectedly, structural proteomics data revealed that the CTR does
not directly interact with RNA, while accelerating RNA release from NSP2. Cryo–electron
microscopy reconstructions of an NSP2–RNA complex reveal a highly conserved acidic
patch on the CTR, which is poised toward the bound RNA. Virus replication was
abrogated by charge-disrupting mutations within the acidic patch but completely
restored by charge-preserving mutations. Mechanistic similarities between NSP2
and the unrelated bacterial RNA chaperone Hfq suggest that accelerating RNA dissociation
while promoting intermolecular RNA interactions may be a widespread strategy of
RNA chaperone recycling.
article_number: e2100198118
article_processing_charge: No
article_type: original
author:
- first_name: Jack Peter Kelly
full_name: Bravo, Jack Peter Kelly
id: 96aecfa5-8931-11ee-af30-aa6a5d6eee0e
last_name: Bravo
orcid: 0000-0003-0456-0753
- first_name: Kira
full_name: Bartnik, Kira
last_name: Bartnik
- first_name: Luca
full_name: Venditti, Luca
last_name: Venditti
- first_name: Julia
full_name: Acker, Julia
last_name: Acker
- first_name: Emma H.
full_name: Gail, Emma H.
last_name: Gail
- first_name: Alice
full_name: Colyer, Alice
last_name: Colyer
- first_name: Chen
full_name: Davidovich, Chen
last_name: Davidovich
- first_name: Don C.
full_name: Lamb, Don C.
last_name: Lamb
- first_name: Roman
full_name: Tuma, Roman
last_name: Tuma
- first_name: Antonio N.
full_name: Calabrese, Antonio N.
last_name: Calabrese
- first_name: Alexander
full_name: Borodavka, Alexander
last_name: Borodavka
citation:
ama: Bravo JPK, Bartnik K, Venditti L, et al. Structural basis of rotavirus RNA
chaperone displacement and RNA annealing. Proceedings of the National Academy
of Sciences. 2021;118(41). doi:10.1073/pnas.2100198118
apa: Bravo, J. P. K., Bartnik, K., Venditti, L., Acker, J., Gail, E. H., Colyer,
A., … Borodavka, A. (2021). Structural basis of rotavirus RNA chaperone displacement
and RNA annealing. Proceedings of the National Academy of Sciences. Proceedings
of the National Academy of Sciences. https://doi.org/10.1073/pnas.2100198118
chicago: Bravo, Jack Peter Kelly, Kira Bartnik, Luca Venditti, Julia Acker, Emma
H. Gail, Alice Colyer, Chen Davidovich, et al. “Structural Basis of Rotavirus
RNA Chaperone Displacement and RNA Annealing.” Proceedings of the National
Academy of Sciences. Proceedings of the National Academy of Sciences, 2021.
https://doi.org/10.1073/pnas.2100198118.
ieee: J. P. K. Bravo et al., “Structural basis of rotavirus RNA chaperone
displacement and RNA annealing,” Proceedings of the National Academy of Sciences,
vol. 118, no. 41. Proceedings of the National Academy of Sciences, 2021.
ista: Bravo JPK, Bartnik K, Venditti L, Acker J, Gail EH, Colyer A, Davidovich C,
Lamb DC, Tuma R, Calabrese AN, Borodavka A. 2021. Structural basis of rotavirus
RNA chaperone displacement and RNA annealing. Proceedings of the National Academy
of Sciences. 118(41), e2100198118.
mla: Bravo, Jack Peter Kelly, et al. “Structural Basis of Rotavirus RNA Chaperone
Displacement and RNA Annealing.” Proceedings of the National Academy of Sciences,
vol. 118, no. 41, e2100198118, Proceedings of the National Academy of Sciences,
2021, doi:10.1073/pnas.2100198118.
short: J.P.K. Bravo, K. Bartnik, L. Venditti, J. Acker, E.H. Gail, A. Colyer, C.
Davidovich, D.C. Lamb, R. Tuma, A.N. Calabrese, A. Borodavka, Proceedings of the
National Academy of Sciences 118 (2021).
date_created: 2024-03-20T10:42:45Z
date_published: 2021-10-06T00:00:00Z
date_updated: 2024-06-04T06:04:07Z
day: '06'
doi: 10.1073/pnas.2100198118
extern: '1'
external_id:
pmid:
- '34615715'
intvolume: ' 118'
issue: '41'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1073/pnas.2100198118
month: '10'
oa: 1
oa_version: Published Version
pmid: 1
publication: Proceedings of the National Academy of Sciences
publication_identifier:
eissn:
- 1091-6490
issn:
- 0027-8424
publication_status: published
publisher: Proceedings of the National Academy of Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Structural basis of rotavirus RNA chaperone displacement and RNA annealing
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 118
year: '2021'
...
---
_id: '15140'
abstract:
- lang: eng
text: Remdesivir is a nucleoside analog approved by the US FDA for treatment of
COVID-19. Here, we present a 3.9-Å-resolution cryo-EM reconstruction of a remdesivir-stalled
RNA-dependent RNA polymerase complex, revealing full incorporation of 3 copies
of remdesivir monophosphate (RMP) and a partially incorporated fourth RMP in the
active site. The structure reveals that RMP blocks RNA translocation after incorporation
of 3 bases following RMP, resulting in delayed chain termination, which can guide
the rational design of improved antiviral drugs.
article_processing_charge: No
article_type: original
author:
- first_name: Jack Peter Kelly
full_name: Bravo, Jack Peter Kelly
id: 96aecfa5-8931-11ee-af30-aa6a5d6eee0e
last_name: Bravo
orcid: 0000-0003-0456-0753
- first_name: Tyler L.
full_name: Dangerfield, Tyler L.
last_name: Dangerfield
- first_name: David W.
full_name: Taylor, David W.
last_name: Taylor
- first_name: Kenneth A.
full_name: Johnson, Kenneth A.
last_name: Johnson
citation:
ama: Bravo JPK, Dangerfield TL, Taylor DW, Johnson KA. Remdesivir is a delayed translocation
inhibitor of SARS-CoV-2 replication. Molecular Cell. 2021;81(7):1548-1552.e4.
doi:10.1016/j.molcel.2021.01.035
apa: Bravo, J. P. K., Dangerfield, T. L., Taylor, D. W., & Johnson, K. A. (2021).
Remdesivir is a delayed translocation inhibitor of SARS-CoV-2 replication. Molecular
Cell. Elsevier. https://doi.org/10.1016/j.molcel.2021.01.035
chicago: Bravo, Jack Peter Kelly, Tyler L. Dangerfield, David W. Taylor, and Kenneth
A. Johnson. “Remdesivir Is a Delayed Translocation Inhibitor of SARS-CoV-2 Replication.”
Molecular Cell. Elsevier, 2021. https://doi.org/10.1016/j.molcel.2021.01.035.
ieee: J. P. K. Bravo, T. L. Dangerfield, D. W. Taylor, and K. A. Johnson, “Remdesivir
is a delayed translocation inhibitor of SARS-CoV-2 replication,” Molecular
Cell, vol. 81, no. 7. Elsevier, p. 1548–1552.e4, 2021.
ista: Bravo JPK, Dangerfield TL, Taylor DW, Johnson KA. 2021. Remdesivir is a delayed
translocation inhibitor of SARS-CoV-2 replication. Molecular Cell. 81(7), 1548–1552.e4.
mla: Bravo, Jack Peter Kelly, et al. “Remdesivir Is a Delayed Translocation Inhibitor
of SARS-CoV-2 Replication.” Molecular Cell, vol. 81, no. 7, Elsevier, 2021,
p. 1548–1552.e4, doi:10.1016/j.molcel.2021.01.035.
short: J.P.K. Bravo, T.L. Dangerfield, D.W. Taylor, K.A. Johnson, Molecular Cell
81 (2021) 1548–1552.e4.
date_created: 2024-03-20T10:42:53Z
date_published: 2021-04-01T00:00:00Z
date_updated: 2024-06-04T06:00:56Z
day: '01'
doi: 10.1016/j.molcel.2021.01.035
extern: '1'
external_id:
pmid:
- '33631104'
intvolume: ' 81'
issue: '7'
keyword:
- Cell Biology
- Molecular Biology
language:
- iso: eng
main_file_link:
- open_access: '1'
url: 'https://doi.org/10.1101/2020.12.14.422718 '
month: '04'
oa: 1
oa_version: Preprint
page: 1548-1552.e4
pmid: 1
publication: Molecular Cell
publication_identifier:
issn:
- 1097-2765
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Remdesivir is a delayed translocation inhibitor of SARS-CoV-2 replication
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 81
year: '2021'
...