---
_id: '17115'
abstract:
- lang: eng
text: Cascades are RNA-guided multi-subunit CRISPR-Cas surveillances complexes that
target foreign nucleic acids for destruction. Here, we present a 2.9-Å resolution
cryo-electron (cryo-EM) structure of the D. vulgaris
type I-C Cascade bound to a double-stranded (ds)DNA target. Our data shows how
the 5’-TTC-3’ protospacer adjacent motif (PAM) sequence is recognized, and provides
a unique mechanism through which the displaced, single-stranded non-target strand
(NTS) is stabilized via stacking interactions with protein subunits in order to
favor R-loop formation and prevent dsDNA re-annealing. Additionally, we provide
structural insights into how diverse anti-CRISPR (Acr) proteins utilize distinct
strategies to achieve a shared mechanism of type I-C Cascade inhibition by blocking
initial DNA binding. These observations provide a structural basis for directional
R-loop formation and reveal how divergent Acr proteins have converged upon common
molecular mechanisms to efficiently shut down CRISPR immunity.
article_processing_charge: No
author:
- first_name: Roisin E.
full_name: O’Brien, Roisin E.
last_name: O’Brien
- first_name: Jack Peter Kelly
full_name: Bravo, Jack Peter Kelly
id: 96aecfa5-8931-11ee-af30-aa6a5d6eee0e
last_name: Bravo
orcid: 0000-0003-0456-0753
- first_name: Delisa
full_name: Ramos, Delisa
last_name: Ramos
- first_name: Grace N.
full_name: Hibshman, Grace N.
last_name: Hibshman
- first_name: Jacquelyn T.
full_name: Wright, Jacquelyn T.
last_name: Wright
- first_name: David W.
full_name: Taylor, David W.
last_name: Taylor
citation:
ama: O’Brien RE, Bravo JPK, Ramos D, Hibshman GN, Wright JT, Taylor DW. Modes of
inhibition used by phage anti-CRISPRs to evade type I-C Cascade. bioRxiv.
2022. doi:10.1101/2022.06.15.496202
apa: O’Brien, R. E., Bravo, J. P. K., Ramos, D., Hibshman, G. N., Wright, J. T.,
& Taylor, D. W. (2022). Modes of inhibition used by phage anti-CRISPRs to
evade type I-C Cascade. bioRxiv. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2022.06.15.496202
chicago: O’Brien, Roisin E., Jack Peter Kelly Bravo, Delisa Ramos, Grace N. Hibshman,
Jacquelyn T. Wright, and David W. Taylor. “Modes of Inhibition Used by Phage Anti-CRISPRs
to Evade Type I-C Cascade.” BioRxiv. Cold Spring Harbor Laboratory, 2022.
https://doi.org/10.1101/2022.06.15.496202.
ieee: R. E. O’Brien, J. P. K. Bravo, D. Ramos, G. N. Hibshman, J. T. Wright, and
D. W. Taylor, “Modes of inhibition used by phage anti-CRISPRs to evade type I-C
Cascade,” bioRxiv. Cold Spring Harbor Laboratory, 2022.
ista: O’Brien RE, Bravo JPK, Ramos D, Hibshman GN, Wright JT, Taylor DW. 2022. Modes
of inhibition used by phage anti-CRISPRs to evade type I-C Cascade. bioRxiv, 10.1101/2022.06.15.496202.
mla: O’Brien, Roisin E., et al. “Modes of Inhibition Used by Phage Anti-CRISPRs
to Evade Type I-C Cascade.” BioRxiv, Cold Spring Harbor Laboratory, 2022,
doi:10.1101/2022.06.15.496202.
short: R.E. O’Brien, J.P.K. Bravo, D. Ramos, G.N. Hibshman, J.T. Wright, D.W. Taylor,
BioRxiv (2022).
date_created: 2024-06-04T06:43:30Z
date_published: 2022-06-15T00:00:00Z
date_updated: 2024-06-04T07:03:02Z
day: '15'
doi: 10.1101/2022.06.15.496202
extern: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1101/2022.06.15.496202
month: '06'
oa: 1
oa_version: Preprint
publication: bioRxiv
publication_status: published
publisher: Cold Spring Harbor Laboratory
status: public
title: Modes of inhibition used by phage anti-CRISPRs to evade type I-C Cascade
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2022'
...
---
_id: '17116'
abstract:
- lang: eng
text: CRISPR (Clustered regularly interspaced short palindromic repeats)-Cas (CRISPR-associated)
systems are a type of adaptive immune response in bacteria and archaea that utilize
crRNA (CRISPR RNA)-guided effector complexes to target complementary RNA or DNA
for destruction. The prototypical type III-A and III-B CRISPR-Cas systems utilize
multi-subunit effector complexes composed of individual proteins to cleave ssRNA
targets at 6-nt intervals, as well as non-specifically degrading ssDNA and activating
cyclic oligoadenylate (cOA) synthesis. Recent studies have shown that type III
systems can contain subunit fusions yet maintain canonical type III RNA-targeting
capabilities. To understand how a multi-subunit fusion effector functions, we
determine structures of a variant type III-D effector and biochemically characterize
how it cleaves RNA targets. These findings provide insights into how multi-subunit
fusion proteins are tethered together and assemble into an active and programmable
RNA endonuclease, how the effector utilizes a novel mechanism for target RNA seeding,
and the structural basis for the evolution of type III effector complexes. Furthermore,
our results provide a blueprint for fusing subunits in class 1 effectors for design
of user-defined effector complexes with disparate activities.Important
noteWhile this manuscript was in preparation, a manuscript
describing the structure of the type III-E effector was published1.
We reference these important findings; however, a careful comparison of the structures
will follow once the coordinates have been released by the PDB.
article_processing_charge: No
author:
- first_name: Evan A.
full_name: Schwartz, Evan A.
last_name: Schwartz
- first_name: Jack Peter Kelly
full_name: Bravo, Jack Peter Kelly
id: 96aecfa5-8931-11ee-af30-aa6a5d6eee0e
last_name: Bravo
orcid: 0000-0003-0456-0753
- first_name: Luis A.
full_name: Macias, Luis A.
last_name: Macias
- first_name: Caitlyn L.
full_name: McCafferty, Caitlyn L.
last_name: McCafferty
- first_name: Tyler L.
full_name: Dangerfield, Tyler L.
last_name: Dangerfield
- first_name: Jada N.
full_name: Walker, Jada N.
last_name: Walker
- first_name: Jennifer S.
full_name: Brodbelt, Jennifer S.
last_name: Brodbelt
- first_name: Peter C.
full_name: Fineran, Peter C.
last_name: Fineran
- first_name: Robert D.
full_name: Fagerlund, Robert D.
last_name: Fagerlund
- first_name: David W.
full_name: Taylor, David W.
last_name: Taylor
citation:
ama: Schwartz EA, Bravo JPK, Macias LA, et al. Assembly of multi-subunit fusion
proteins into the RNA-targeting type III-D CRISPR-Cas effector complex. bioRxiv.
doi:10.1101/2022.06.13.496011
apa: Schwartz, E. A., Bravo, J. P. K., Macias, L. A., McCafferty, C. L., Dangerfield,
T. L., Walker, J. N., … Taylor, D. W. (n.d.). Assembly of multi-subunit fusion
proteins into the RNA-targeting type III-D CRISPR-Cas effector complex. bioRxiv.
Cold Spring Harbor Laboratory. https://doi.org/10.1101/2022.06.13.496011
chicago: Schwartz, Evan A., Jack Peter Kelly Bravo, Luis A. Macias, Caitlyn L. McCafferty,
Tyler L. Dangerfield, Jada N. Walker, Jennifer S. Brodbelt, Peter C. Fineran,
Robert D. Fagerlund, and David W. Taylor. “Assembly of Multi-Subunit Fusion Proteins
into the RNA-Targeting Type III-D CRISPR-Cas Effector Complex.” BioRxiv.
Cold Spring Harbor Laboratory, n.d. https://doi.org/10.1101/2022.06.13.496011.
ieee: E. A. Schwartz et al., “Assembly of multi-subunit fusion proteins into
the RNA-targeting type III-D CRISPR-Cas effector complex,” bioRxiv. Cold
Spring Harbor Laboratory.
ista: Schwartz EA, Bravo JPK, Macias LA, McCafferty CL, Dangerfield TL, Walker JN,
Brodbelt JS, Fineran PC, Fagerlund RD, Taylor DW. Assembly of multi-subunit fusion
proteins into the RNA-targeting type III-D CRISPR-Cas effector complex. bioRxiv,
10.1101/2022.06.13.496011.
mla: Schwartz, Evan A., et al. “Assembly of Multi-Subunit Fusion Proteins into the
RNA-Targeting Type III-D CRISPR-Cas Effector Complex.” BioRxiv, Cold Spring
Harbor Laboratory, doi:10.1101/2022.06.13.496011.
short: E.A. Schwartz, J.P.K. Bravo, L.A. Macias, C.L. McCafferty, T.L. Dangerfield,
J.N. Walker, J.S. Brodbelt, P.C. Fineran, R.D. Fagerlund, D.W. Taylor, BioRxiv
(n.d.).
date_created: 2024-06-04T06:44:16Z
date_published: 2022-06-14T00:00:00Z
date_updated: 2024-06-04T06:58:41Z
day: '14'
doi: 10.1101/2022.06.13.496011
extern: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1101/2022.06.13.496011
month: '06'
oa: 1
oa_version: Preprint
publication: bioRxiv
publication_status: submitted
publisher: Cold Spring Harbor Laboratory
status: public
title: Assembly of multi-subunit fusion proteins into the RNA-targeting type III-D
CRISPR-Cas effector complex
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2022'
...
---
_id: '17117'
abstract:
- lang: eng
text: Cas12a2 is a CRISPR-associated nuclease that performs RNA-guided degradation
of non-specific single-stranded (ss)RNA, ssDNA and double-stranded (ds)DNA upon
recognition of a complementary RNA target, culminating in abortive infection (Dmytrenko
2022). Here, we report structures of Cas12a2 in binary, ternary, and quaternary
complexes to reveal a complete activation pathway. Our structures reveal that
Cas12a2 is autoinhibited until binding a cognate RNA target, which exposes the
RuvC active site within a large, positively charged cleft. Double-stranded DNA
substrates are captured through duplex distortion and local melting, stabilized
by pairs of ‘aromatic clamp’ residues that are crucial for dsDNA degradation and
in vivo immune system function. Our work provides a
structural basis for this unprecedented mechanism of abortive infection to achieve
population-level immunity, which can be leveraged to create rational mutants that
degrade a spectrum of collateral substrates.
article_processing_charge: No
author:
- first_name: Jack Peter Kelly
full_name: Bravo, Jack Peter Kelly
id: 96aecfa5-8931-11ee-af30-aa6a5d6eee0e
last_name: Bravo
orcid: 0000-0003-0456-0753
- first_name: Thom
full_name: Hallmark, Thom
last_name: Hallmark
- first_name: Bronson
full_name: Naegle, Bronson
last_name: Naegle
- first_name: Chase L.
full_name: Beisel, Chase L.
last_name: Beisel
- first_name: Ryan N.
full_name: Jackson, Ryan N.
last_name: Jackson
- first_name: David W.
full_name: Taylor, David W.
last_name: Taylor
citation:
ama: Bravo JPK, Hallmark T, Naegle B, Beisel CL, Jackson RN, Taylor DW. Large-scale
structural rearrangements unleash indiscriminate nuclease activity of CRISPR-Cas12a2.
bioRxiv. 2022. doi:10.1101/2022.06.13.495754
apa: Bravo, J. P. K., Hallmark, T., Naegle, B., Beisel, C. L., Jackson, R. N., &
Taylor, D. W. (2022). Large-scale structural rearrangements unleash indiscriminate
nuclease activity of CRISPR-Cas12a2. bioRxiv. Cold Spring Harbor Laboratory.
https://doi.org/10.1101/2022.06.13.495754
chicago: Bravo, Jack Peter Kelly, Thom Hallmark, Bronson Naegle, Chase L. Beisel,
Ryan N. Jackson, and David W. Taylor. “Large-Scale Structural Rearrangements Unleash
Indiscriminate Nuclease Activity of CRISPR-Cas12a2.” BioRxiv. Cold Spring
Harbor Laboratory, 2022. https://doi.org/10.1101/2022.06.13.495754.
ieee: J. P. K. Bravo, T. Hallmark, B. Naegle, C. L. Beisel, R. N. Jackson, and D.
W. Taylor, “Large-scale structural rearrangements unleash indiscriminate nuclease
activity of CRISPR-Cas12a2,” bioRxiv. Cold Spring Harbor Laboratory, 2022.
ista: Bravo JPK, Hallmark T, Naegle B, Beisel CL, Jackson RN, Taylor DW. 2022. Large-scale
structural rearrangements unleash indiscriminate nuclease activity of CRISPR-Cas12a2.
bioRxiv, 10.1101/2022.06.13.495754.
mla: Bravo, Jack Peter Kelly, et al. “Large-Scale Structural Rearrangements Unleash
Indiscriminate Nuclease Activity of CRISPR-Cas12a2.” BioRxiv, Cold Spring
Harbor Laboratory, 2022, doi:10.1101/2022.06.13.495754.
short: J.P.K. Bravo, T. Hallmark, B. Naegle, C.L. Beisel, R.N. Jackson, D.W. Taylor,
BioRxiv (2022).
date_created: 2024-06-04T06:44:59Z
date_published: 2022-06-13T00:00:00Z
date_updated: 2024-06-04T06:55:16Z
day: '13'
doi: 10.1101/2022.06.13.495754
extern: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1101/2022.06.13.495754
month: '06'
oa: 1
oa_version: Preprint
publication: bioRxiv
publication_status: published
publisher: Cold Spring Harbor Laboratory
status: public
title: Large-scale structural rearrangements unleash indiscriminate nuclease activity
of CRISPR-Cas12a2
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2022'
...
---
OA_place: repository
_id: '17157'
abstract:
- lang: eng
text: An action of a complex reductive group G on a smooth projective variety X
is regular when all regular unipotent elements in G act with finitely many fixed
points. Then the complex G-equivariant cohomology ring of X is isomorphic to the
coordinate ring of a certain regular fixed point scheme. Examples include partial
flag varieties, smooth Schubert varieties and Bott-Samelson varieties. We also
show that a more general version of the fixed point scheme allows a generalisation
to GKM spaces, such as toric varieties.
article_number: '2212.11836'
article_processing_charge: No
arxiv: 1
author:
- first_name: Tamás
full_name: Hausel, Tamás
id: 4A0666D8-F248-11E8-B48F-1D18A9856A87
last_name: Hausel
orcid: 0000-0002-9582-2634
- first_name: Kamil P
full_name: Rychlewicz, Kamil P
id: 85A07246-A8BF-11E9-B4FA-D9E3E5697425
last_name: Rychlewicz
citation:
ama: Hausel T, Rychlewicz KP. Spectrum of equivariant cohomology as a fixed point
scheme. arXiv. doi:10.48550/arXiv.2212.11836
apa: Hausel, T., & Rychlewicz, K. P. (n.d.). Spectrum of equivariant cohomology
as a fixed point scheme. arXiv. https://doi.org/10.48550/arXiv.2212.11836
chicago: Hausel, Tamás, and Kamil P Rychlewicz. “Spectrum of Equivariant Cohomology
as a Fixed Point Scheme.” ArXiv, n.d. https://doi.org/10.48550/arXiv.2212.11836.
ieee: T. Hausel and K. P. Rychlewicz, “Spectrum of equivariant cohomology as a fixed
point scheme,” arXiv. .
ista: Hausel T, Rychlewicz KP. Spectrum of equivariant cohomology as a fixed point
scheme. arXiv, 2212.11836.
mla: Hausel, Tamás, and Kamil P. Rychlewicz. “Spectrum of Equivariant Cohomology
as a Fixed Point Scheme.” ArXiv, 2212.11836, doi:10.48550/arXiv.2212.11836.
short: T. Hausel, K.P. Rychlewicz, ArXiv (n.d.).
date_created: 2024-06-23T15:01:27Z
date_published: 2022-12-22T00:00:00Z
date_updated: 2026-04-07T12:55:46Z
day: '22'
department:
- _id: GradSch
- _id: TaHa
doi: 10.48550/arXiv.2212.11836
external_id:
arxiv:
- '2212.11836'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2212.11836
month: '12'
oa: 1
oa_version: Preprint
publication: arXiv
publication_status: draft
related_material:
record:
- id: '19071'
relation: later_version
status: public
- id: '17156'
relation: dissertation_contains
status: public
status: public
title: Spectrum of equivariant cohomology as a fixed point scheme
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2022'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '18606'
abstract:
- lang: eng
text: "Shear thickening is an intriguing rheological behaviour which consists in
a brutal increase in the viscosity above a critical shear rate. It is famously
encountered in suspensions of corn starch in water. Despite having been discovered
in the early 1930's, its underlying mechanisms remained a mystery for a long time.
In 2013–14, numerical and theoretical works [[1], [2], [3]] put forward a frictional
transition scenario to explain this phenomenon.\r\nIn this talk, I will present
experimental work investigating this frictional transition scenario. In order
to test the ideas of this model, one has to go further than standard rheological
techniques, since they do not provide access to the frictional state of the measured
suspension. I will thus focus on the techniques that we developed in order to
evidence the frictional transition and link it to the presence of a shear-thickening
behaviour."
acknowledgement: "This talk presents parts of my PhD work, conducted at IUSTI in Marseille
under the supervision of Yoël Forterre and Bloen Metzger. It aslo benefited from
contributions from Antoine Bérut, and some of the data was acquired by Pauline Dame
as part of a summer internship.\r\nThis work was supported by the European Research
Council (ERC) under the European Union Horizon 2020 Research and Innovation program
(ERC Grant 647384) and by the Labex MEC (ANR-10-LABX-0092) under the 647384) and
by the A*MIDEX project (ANR-11-IDEX-0001-02) funded by the French government program
Investissements d'Avenir, and by ANR ScienceFriction (No. ANR-18-CE30-0024)."
article_number: '100038'
article_processing_charge: No
article_type: original
author:
- first_name: Cécile
full_name: Clavaud, Cécile
id: 5f654c5d-04a1-11eb-ab36-ba9ffec58bd8
last_name: Clavaud
orcid: 0000-0002-1843-3803
citation:
ama: 'Clavaud C. Shear thickening in dense suspensions: an experimental study. Science
Talks. 2022;3. doi:10.1016/j.sctalk.2022.100038'
apa: 'Clavaud, C. (2022). Shear thickening in dense suspensions: an experimental
study. Science Talks. Elsevier. https://doi.org/10.1016/j.sctalk.2022.100038'
chicago: 'Clavaud, Cécile. “Shear Thickening in Dense Suspensions: An Experimental
Study.” Science Talks. Elsevier, 2022. https://doi.org/10.1016/j.sctalk.2022.100038.'
ieee: 'C. Clavaud, “Shear thickening in dense suspensions: an experimental study,”
Science Talks, vol. 3. Elsevier, 2022.'
ista: 'Clavaud C. 2022. Shear thickening in dense suspensions: an experimental study.
Science Talks. 3, 100038.'
mla: 'Clavaud, Cécile. “Shear Thickening in Dense Suspensions: An Experimental Study.”
Science Talks, vol. 3, 100038, Elsevier, 2022, doi:10.1016/j.sctalk.2022.100038.'
short: C. Clavaud, Science Talks 3 (2022).
corr_author: '1'
date_created: 2024-12-01T23:01:55Z
date_published: 2022-08-01T00:00:00Z
date_updated: 2024-12-11T09:24:57Z
day: '01'
ddc:
- '530'
department:
- _id: ScWa
doi: 10.1016/j.sctalk.2022.100038
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creator: dernst
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creator: dernst
date_created: 2024-12-11T09:22:19Z
date_updated: 2024-12-11T09:22:19Z
file_id: '18647'
file_name: 2024_ScienceTalk__Clavaud_QA.mp4
file_size: 58282147
relation: supplementary_material
file_date_updated: 2024-12-11T09:22:19Z
has_accepted_license: '1'
intvolume: ' 3'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '08'
oa: 1
oa_version: Published Version
publication: Science Talks
publication_identifier:
eissn:
- 2772-5693
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Shear thickening in dense suspensions: an experimental study'
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 3
year: '2022'
...
---
OA_place: publisher
OA_type: gold
_id: '18876'
abstract:
- lang: eng
text: Convolutional neural networks were the standard for solving many computer
vision tasks until recently, when Transformers of MLP-based architectures have
started to show competitive performance. These architectures typically have a
vast number of weights and need to be trained on massive datasets; hence, they
are not suitable for their use in low-data regimes. In this work, we propose a
simple yet effective framework to improve generalization from small amounts of
data. We augment modern CNNs with fully-connected (FC) layers and show the massive
impact this architectural change has in low-data regimes. We further present an
online joint knowledge-distillation method to utilize the extra FC layers at train
time but avoid them during test time. This allows us to improve the generalization
of a CNN-based model without any increase in the number of weights at test time.
We perform classification experiments for a large range of network backbones and
several standard datasets on supervised learning and active learning. Our experiments
significantly outperform the networks without fully-connected layers, reaching
a relative improvement of up to 16% validation accuracy in the supervised setting
without adding any extra parameters during inference.
acknowledgement: "This work was supported by a Sofja Kovalevskaja Award, a postdoc
fellowship\r\nfrom the Humboldt Foundation, the ERC Starting Grant Scan2CAD (804724),
and the German\r\nResearch Foundation (DFG) Research Unit \"Learning and Simulation
in Visual Computing\"."
alternative_title:
- Advances in Neural Information Processing Systems
article_processing_charge: No
arxiv: 1
author:
- first_name: Peter
full_name: Kocsis, Peter
last_name: Kocsis
- first_name: Peter
full_name: Súkeník, Peter
id: d64d6a8d-eb8e-11eb-b029-96fd216dec3c
last_name: Súkeník
- first_name: Guillem
full_name: Brasó, Guillem
last_name: Brasó
- first_name: Matthias
full_name: Niessner, Matthias
last_name: Niessner
- first_name: Laura
full_name: Leal-Taixé, Laura
last_name: Leal-Taixé
- first_name: Ismail
full_name: Elezi, Ismail
last_name: Elezi
citation:
ama: 'Kocsis P, Súkeník P, Brasó G, Niessner M, Leal-Taixé L, Elezi I. The unreasonable
effectiveness of fully-connected layers for low-data regimes. In: 36th Conference
on Neural Information Processing Systems. Vol 35. Neural Information Processing
Systems Foundation; 2022:1896-1908.'
apa: 'Kocsis, P., Súkeník, P., Brasó, G., Niessner, M., Leal-Taixé, L., & Elezi,
I. (2022). The unreasonable effectiveness of fully-connected layers for low-data
regimes. In 36th Conference on Neural Information Processing Systems (Vol.
35, pp. 1896–1908). New Orleans, LA, United States: Neural Information Processing
Systems Foundation.'
chicago: Kocsis, Peter, Peter Súkeník, Guillem Brasó, Matthias Niessner, Laura Leal-Taixé,
and Ismail Elezi. “The Unreasonable Effectiveness of Fully-Connected Layers for
Low-Data Regimes.” In 36th Conference on Neural Information Processing Systems,
35:1896–1908. Neural Information Processing Systems Foundation, 2022.
ieee: P. Kocsis, P. Súkeník, G. Brasó, M. Niessner, L. Leal-Taixé, and I. Elezi,
“The unreasonable effectiveness of fully-connected layers for low-data regimes,”
in 36th Conference on Neural Information Processing Systems, New Orleans,
LA, United States, 2022, vol. 35, pp. 1896–1908.
ista: 'Kocsis P, Súkeník P, Brasó G, Niessner M, Leal-Taixé L, Elezi I. 2022. The
unreasonable effectiveness of fully-connected layers for low-data regimes. 36th
Conference on Neural Information Processing Systems. NeurIPS: Neural Information
Processing Systems, Advances in Neural Information Processing Systems, vol. 35,
1896–1908.'
mla: Kocsis, Peter, et al. “The Unreasonable Effectiveness of Fully-Connected Layers
for Low-Data Regimes.” 36th Conference on Neural Information Processing Systems,
vol. 35, Neural Information Processing Systems Foundation, 2022, pp. 1896–908.
short: P. Kocsis, P. Súkeník, G. Brasó, M. Niessner, L. Leal-Taixé, I. Elezi, in:,
36th Conference on Neural Information Processing Systems, Neural Information Processing
Systems Foundation, 2022, pp. 1896–1908.
conference:
end_date: 2022-12-09
location: New Orleans, LA, United States
name: 'NeurIPS: Neural Information Processing Systems'
start_date: 2022-11-28
date_created: 2025-01-24T19:16:01Z
date_published: 2022-12-01T00:00:00Z
date_updated: 2025-07-10T11:51:28Z
day: '01'
ddc:
- '000'
extern: '1'
external_id:
arxiv:
- '2210.05657'
file:
- access_level: open_access
checksum: 2a14e59ef8b34d9a1a27a7adbc6f83ff
content_type: application/pdf
creator: psukenik
date_created: 2025-01-24T19:13:32Z
date_updated: 2025-01-24T19:13:32Z
file_id: '18877'
file_name: NeurIPS-2022-the-unreasonable-effectiveness-of-fully-connected-layers-for-low-data-regimes-Paper-Conference.pdf
file_size: 444819
relation: main_file
success: 1
file_date_updated: 2025-01-24T19:13:32Z
has_accepted_license: '1'
intvolume: ' 35'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 1896-1908
publication: 36th Conference on Neural Information Processing Systems
publication_identifier:
issn:
- 1049-5258
publication_status: published
publisher: Neural Information Processing Systems Foundation
quality_controlled: '1'
scopus_import: '1'
status: public
title: The unreasonable effectiveness of fully-connected layers for low-data regimes
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 35
year: '2022'
...
---
OA_place: repository
OA_type: green
_id: '19490'
abstract:
- lang: eng
text: "Abstract. We study integral points on the quadratic twists ED : y2 = x3 −\r\nD2x
of the congruent number curve. We give upper bounds on the number of\r\nintegral
points in each coset of 2ED(Q) in ED(Q) and show that their total is\r\n (3.8)rank
ED(Q). We further show that the average number of non-torsion\r\nintegral points
in this family is bounded above by 2. As an application we also\r\ndeduce from
our upper bounds that the system of simultaneous Pell equations\r\naX2 − bY 2
= d, bY 2 − cZ2 = d for pairwise coprime positive integers a, b, c, d,\r\nhas
at most (3.6)ω(abcd) integer solutions."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Yik Tung
full_name: Chan, Yik Tung
id: c4c0afc8-9262-11ed-9231-d8b0bc743af1
last_name: Chan
orcid: 0000-0001-8467-4106
citation:
ama: Chan S. Integral points on the congruent number curve. Transactions of the
American Mathematical Society. 2022;375(9):6675-6700. doi:10.1090/tran/8732
apa: Chan, S. (2022). Integral points on the congruent number curve. Transactions
of the American Mathematical Society. American Mathematical Society. https://doi.org/10.1090/tran/8732
chicago: Chan, Stephanie. “Integral Points on the Congruent Number Curve.” Transactions
of the American Mathematical Society. American Mathematical Society, 2022.
https://doi.org/10.1090/tran/8732.
ieee: S. Chan, “Integral points on the congruent number curve,” Transactions
of the American Mathematical Society, vol. 375, no. 9. American Mathematical
Society, pp. 6675–6700, 2022.
ista: Chan S. 2022. Integral points on the congruent number curve. Transactions
of the American Mathematical Society. 375(9), 6675–6700.
mla: Chan, Stephanie. “Integral Points on the Congruent Number Curve.” Transactions
of the American Mathematical Society, vol. 375, no. 9, American Mathematical
Society, 2022, pp. 6675–700, doi:10.1090/tran/8732.
short: S. Chan, Transactions of the American Mathematical Society 375 (2022) 6675–6700.
date_created: 2025-04-05T10:50:56Z
date_published: 2022-09-01T00:00:00Z
date_updated: 2025-07-10T11:51:47Z
day: '01'
doi: 10.1090/tran/8732
extern: '1'
external_id:
arxiv:
- '2004.03331'
intvolume: ' 375'
issue: '9'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2004.03331
month: '09'
oa: 1
oa_version: Preprint
page: 6675-6700
publication: Transactions of the American Mathematical Society
publication_identifier:
eissn:
- 1088-6850
issn:
- 0002-9947
publication_status: published
publisher: American Mathematical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Integral points on the congruent number curve
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 375
year: '2022'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '19491'
abstract:
- lang: eng
text: Using a recent breakthrough of Smith [18], we improve the results of Fouvry
and Klüners [4, 5] on the solubility of the negative Pell equation. Let D denote
the set of positive squarefree integers having no prime factors congruent to 3
modulo 4 . Stevenhagen [19] conjectured that the density of d in D such that the
negative Pell equation x2−dy2=−1 is solvable with x,y∈Z is 58.1% , to the nearest
tenth of a percent. By studying the distribution of the 8 -rank of narrow class
groups Cl+(d) of Q(√d) , we prove that the infimum of this density is at least
53.8% .
article_number: e46
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Yik Tung
full_name: Chan, Yik Tung
id: c4c0afc8-9262-11ed-9231-d8b0bc743af1
last_name: Chan
orcid: 0000-0001-8467-4106
- first_name: Peter
full_name: Koymans, Peter
last_name: Koymans
- first_name: Djordjo
full_name: Milovic, Djordjo
last_name: Milovic
- first_name: Carlo
full_name: Pagano, Carlo
last_name: Pagano
citation:
ama: Chan S, Koymans P, Milovic D, Pagano C. The 8-rank of the narrow class group
and the negative Pell equation. Forum of Mathematics, Sigma. 2022;10. doi:10.1017/fms.2022.40
apa: Chan, S., Koymans, P., Milovic, D., & Pagano, C. (2022). The 8-rank of
the narrow class group and the negative Pell equation. Forum of Mathematics,
Sigma. Cambridge University Press. https://doi.org/10.1017/fms.2022.40
chicago: Chan, Stephanie, Peter Koymans, Djordjo Milovic, and Carlo Pagano. “The
8-Rank of the Narrow Class Group and the Negative Pell Equation.” Forum of
Mathematics, Sigma. Cambridge University Press, 2022. https://doi.org/10.1017/fms.2022.40.
ieee: S. Chan, P. Koymans, D. Milovic, and C. Pagano, “The 8-rank of the narrow
class group and the negative Pell equation,” Forum of Mathematics, Sigma,
vol. 10. Cambridge University Press, 2022.
ista: Chan S, Koymans P, Milovic D, Pagano C. 2022. The 8-rank of the narrow class
group and the negative Pell equation. Forum of Mathematics, Sigma. 10, e46.
mla: Chan, Stephanie, et al. “The 8-Rank of the Narrow Class Group and the Negative
Pell Equation.” Forum of Mathematics, Sigma, vol. 10, e46, Cambridge University
Press, 2022, doi:10.1017/fms.2022.40.
short: S. Chan, P. Koymans, D. Milovic, C. Pagano, Forum of Mathematics, Sigma 10
(2022).
date_created: 2025-04-05T10:51:00Z
date_published: 2022-05-17T00:00:00Z
date_updated: 2025-07-10T11:51:47Z
day: '17'
ddc:
- '510'
doi: 10.1017/fms.2022.40
extern: '1'
external_id:
arxiv:
- '1908.01752'
has_accepted_license: '1'
intvolume: ' 10'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
main_file_link:
- open_access: '1'
url: https://doi.org/10.1017/fms.2022.40
month: '05'
oa: 1
oa_version: Published Version
publication: Forum of Mathematics, Sigma
publication_identifier:
issn:
- 2050-5094
publication_status: published
publisher: Cambridge University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: The 8-rank of the narrow class group and the negative Pell equation
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10
year: '2022'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '19822'
abstract:
- lang: eng
text: '>Controlling spin wave excitations in magnetic materials underpins the burgeoning
field of magnonics. Yet, little is known about how magnons interact with the conduction
electrons of itinerant magnets, or how this interplay can be controlled. Via a
surface-sensitive spectroscopic approach, we demonstrate a strong electron–magnon
coupling at the Pd-terminated surface of the delafossite oxide PdCoO2, where a
polar surface charge mediates a Stoner transition to itinerant surface ferromagnetism.
We show how the coupling is enhanced sevenfold with increasing surface disorder,
and concomitant charge carrier doping, becoming sufficiently strong to drive the
system into a polaronic regime, accompanied by a significant quasiparticle mass
enhancement. Our study thus sheds light on electron–magnon interactions in solid-state
materials, and the ways in which these can be controlled.'
article_number: '20'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: F.
full_name: Mazzola, F.
last_name: Mazzola
- first_name: C. -M.
full_name: Yim, C. -M.
last_name: Yim
- first_name: Veronika
full_name: Sunko, Veronika
id: 23cb1cf6-2c7a-11ef-91a4-f72fc19f20b3
last_name: Sunko
orcid: 0000-0003-2724-3523
- first_name: S.
full_name: Khim, S.
last_name: Khim
- first_name: P.
full_name: Kushwaha, P.
last_name: Kushwaha
- first_name: O. J.
full_name: Clark, O. J.
last_name: Clark
- first_name: L.
full_name: Bawden, L.
last_name: Bawden
- first_name: I.
full_name: Marković, I.
last_name: Marković
- first_name: D.
full_name: Chakraborti, D.
last_name: Chakraborti
- first_name: T. K.
full_name: Kim, T. K.
last_name: Kim
- first_name: M.
full_name: Hoesch, M.
last_name: Hoesch
- first_name: A. P.
full_name: Mackenzie, A. P.
last_name: Mackenzie
- first_name: P.
full_name: Wahl, P.
last_name: Wahl
- first_name: P. D. C.
full_name: King, P. D. C.
last_name: King
citation:
ama: Mazzola F, Yim C-M, Sunko V, et al. Tuneable electron–magnon coupling of ferromagnetic
surface states in PdCoO2. npj Quantum Materials. 2022;7. doi:10.1038/s41535-022-00428-8
apa: Mazzola, F., Yim, C.-M., Sunko, V., Khim, S., Kushwaha, P., Clark, O. J., …
King, P. D. C. (2022). Tuneable electron–magnon coupling of ferromagnetic surface
states in PdCoO2. Npj Quantum Materials. Springer Nature. https://doi.org/10.1038/s41535-022-00428-8
chicago: Mazzola, F., C. -M. Yim, Veronika Sunko, S. Khim, P. Kushwaha, O. J. Clark,
L. Bawden, et al. “Tuneable Electron–Magnon Coupling of Ferromagnetic Surface
States in PdCoO2.” Npj Quantum Materials. Springer Nature, 2022. https://doi.org/10.1038/s41535-022-00428-8.
ieee: F. Mazzola et al., “Tuneable electron–magnon coupling of ferromagnetic
surface states in PdCoO2,” npj Quantum Materials, vol. 7. Springer Nature,
2022.
ista: Mazzola F, Yim C-M, Sunko V, Khim S, Kushwaha P, Clark OJ, Bawden L, Marković
I, Chakraborti D, Kim TK, Hoesch M, Mackenzie AP, Wahl P, King PDC. 2022. Tuneable
electron–magnon coupling of ferromagnetic surface states in PdCoO2. npj Quantum
Materials. 7, 20.
mla: Mazzola, F., et al. “Tuneable Electron–Magnon Coupling of Ferromagnetic Surface
States in PdCoO2.” Npj Quantum Materials, vol. 7, 20, Springer Nature,
2022, doi:10.1038/s41535-022-00428-8.
short: F. Mazzola, C.-M. Yim, V. Sunko, S. Khim, P. Kushwaha, O.J. Clark, L. Bawden,
I. Marković, D. Chakraborti, T.K. Kim, M. Hoesch, A.P. Mackenzie, P. Wahl, P.D.C.
King, Npj Quantum Materials 7 (2022).
date_created: 2025-06-10T09:20:49Z
date_published: 2022-02-11T00:00:00Z
date_updated: 2025-06-10T13:13:32Z
day: '11'
doi: 10.1038/s41535-022-00428-8
extern: '1'
external_id:
arxiv:
- '2112.04869'
intvolume: ' 7'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1038/s41535-022-00428-8
month: '02'
oa: 1
oa_version: Published Version
publication: npj Quantum Materials
publication_identifier:
eissn:
- 2397-4648
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Tuneable electron–magnon coupling of ferromagnetic surface states in PdCoO2
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2022'
...
---
OA_place: publisher
OA_type: gold
_id: '19984'
abstract:
- lang: eng
text: "The first part of this paper is a survey of mathematical results on mirror
symmetry phenomena between Hitchin systems for Langlands dual groups. The second
part introduces\r\nand discusses multiplicity algebras of the Hitchin system on
Lagrangians, and considers\r\ncorresponding conjectural structures on their mirror."
acknowledgement: "The author thanks Nigel Hitchin for introducing him to Higgs bundles
during 1995–1998,\r\nsuggesting the SYZ picture for Langlands dual Hitchin systems
in 1996, and for the\r\nmore recent collaborations [29, 30]. He also thanks David
Ben-Zvi, Pierre-Henri Chaudouard, Pierre Deligne, Ron Donagi, Sergei Gukov, Jochen
Heinloth, Vadim Kaloshin,\r\nJoel Kamnitzer, Gérard Laumon, Anton Mellit, David
Nadler, Andy Neitzke, Ngô Bao\r\nChâu, Michael Thaddeus, Tony Pantev, Du Pei, Richárd
Rimányi, Leonid Rybnikov, Vivek\r\nShende, Balázs Szendrői, András Szenes, Fernando
Rodriguez-Villegas, Edward Witten,\r\nand Zhiwei Yun for discussions about the subjects
in this paper over the years. Thanks are\r\nalso due to Hülya Argüz, Jakub Löwit,
Balázs Szendrői, and Nigel Hitchin for the careful\r\nreading of the paper."
article_processing_charge: No
arxiv: 1
author:
- first_name: Tamás
full_name: Hausel, Tamás
id: 4A0666D8-F248-11E8-B48F-1D18A9856A87
last_name: Hausel
orcid: 0000-0002-9582-2634
citation:
ama: 'Hausel T. Enhanced mirror symmetry for Langlands dual Hitchin systems. In:
International Congress of Mathematicians. EMS Press; 2022:2228-2249. doi:10.4171/icm2022/164'
apa: 'Hausel, T. (2022). Enhanced mirror symmetry for Langlands dual Hitchin systems.
In International Congress of Mathematicians (pp. 2228–2249). virtuel: EMS
Press. https://doi.org/10.4171/icm2022/164'
chicago: Hausel, Tamás. “Enhanced Mirror Symmetry for Langlands Dual Hitchin Systems.”
In International Congress of Mathematicians, 2228–49. EMS Press, 2022.
https://doi.org/10.4171/icm2022/164.
ieee: T. Hausel, “Enhanced mirror symmetry for Langlands dual Hitchin systems,”
in International Congress of Mathematicians, EMS Press, 2022, pp. 2228–2249.
ista: 'Hausel T. 2022.Enhanced mirror symmetry for Langlands dual Hitchin systems.
In: International Congress of Mathematicians. , 2228–2249.'
mla: Hausel, Tamás. “Enhanced Mirror Symmetry for Langlands Dual Hitchin Systems.”
International Congress of Mathematicians, EMS Press, 2022, pp. 2228–49,
doi:10.4171/icm2022/164.
short: T. Hausel, in:, International Congress of Mathematicians, EMS Press, 2022,
pp. 2228–2249.
conference:
end_date: 2022-07-14
location: virtuel
name: 'ICM: International Congress of Mathematicians'
start_date: 2022-07-06
corr_author: '1'
date_created: 2025-07-10T13:13:36Z
date_published: 2022-07-15T00:00:00Z
date_updated: 2025-09-24T09:12:13Z
day: '15'
ddc:
- '510'
department:
- _id: TaHa
doi: 10.4171/icm2022/164
external_id:
arxiv:
- '2112.09455'
file:
- access_level: open_access
checksum: d2b9d4cf51c854f1082d8dc18c5853b1
content_type: application/pdf
creator: dernst
date_created: 2025-09-24T09:05:05Z
date_updated: 2025-09-24T09:05:05Z
file_id: '20387'
file_name: 2022_ICM_Hausel.pdf
file_size: 655370
relation: main_file
success: 1
file_date_updated: 2025-09-24T09:05:05Z
has_accepted_license: '1'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 2228-2249
publication: International Congress of Mathematicians
publication_identifier:
eisbn:
- '9783985475582'
isbn:
- '9783985470587'
publication_status: published
publisher: EMS Press
quality_controlled: '1'
status: public
title: Enhanced mirror symmetry for Langlands dual Hitchin systems
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2022'
...
---
OA_type: closed access
_id: '20062'
abstract:
- lang: eng
text: "This article presents two fine-grained complexity lower bounds with relevance
to algorithmic problems in computer aided verification. We have chosen these lower
bounds as the proofs are relatively simple, but the techniques can be extended
to give lower bounds for many more algorithmic problems. The goal is to present
the bounds with minimal notation, making the results accessible to a broad community
and stimulating further research in the area.\r\n\r\nSpecifically, we first describe
a lower bound on the symbolic complexity of computing strongly connected components,
which can be extended to show lower bounds for fundamental model-checking questions
in graphs, published in [CDHL16b]. Second we present a conditional lower bound
for disjunctive safety problems on graphs from [CDHL18] in the RAM model of computation.
This bound can be modified to give conditional lower bounds for disjunctive objectives
for reachability, Büchi, coBüchi and Rabin objectives in MDPs. We also present
various open questions."
acknowledgement: This project has received funding from the European Research Council
(ERC) under the European Union’s Horizon 2020 research and innovation programme
(Grant agreement No. 101019564 “The Design of Modern Fully Dynamic Data Structures
(MoDynStruct)” and from the Austrian Science Fund (FWF) project “Fast Algorithms
for a Reactive Network Layer (ReactNet)”, P 33775-N, with additional funding from
the netidee SCIENCE Stiftung, 2020–2024.
article_processing_charge: No
author:
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
citation:
ama: 'Henzinger M. Fine-Grained Complexity Lower Bounds for Problems in Computer
Aided Verification. In: Raskin J-F, Chatterjee K, Doyen L, Majumdar R, eds. Principles
of Systems Design. Vol 13660. LNCS. Cham: Springer Nature Switzerland; 2022:292-305.
doi:10.1007/978-3-031-22337-2_14'
apa: 'Henzinger, M. (2022). Fine-Grained Complexity Lower Bounds for Problems in
Computer Aided Verification. In J.-F. Raskin, K. Chatterjee, L. Doyen, & R.
Majumdar (Eds.), Principles of Systems Design (Vol. 13660, pp. 292–305).
Cham: Springer Nature Switzerland. https://doi.org/10.1007/978-3-031-22337-2_14'
chicago: 'Henzinger, Monika. “Fine-Grained Complexity Lower Bounds for Problems
in Computer Aided Verification.” In Principles of Systems Design, edited
by Jean-François Raskin, Krishnendu Chatterjee, Laurent Doyen, and Rupak Majumdar,
13660:292–305. LNCS. Cham: Springer Nature Switzerland, 2022. https://doi.org/10.1007/978-3-031-22337-2_14.'
ieee: 'M. Henzinger, “Fine-Grained Complexity Lower Bounds for Problems in Computer
Aided Verification,” in Principles of Systems Design, vol. 13660, J.-F.
Raskin, K. Chatterjee, L. Doyen, and R. Majumdar, Eds. Cham: Springer Nature Switzerland,
2022, pp. 292–305.'
ista: 'Henzinger M. 2022.Fine-Grained Complexity Lower Bounds for Problems in Computer
Aided Verification. In: Principles of Systems Design. vol. 13660, 292–305.'
mla: Henzinger, Monika. “Fine-Grained Complexity Lower Bounds for Problems in Computer
Aided Verification.” Principles of Systems Design, edited by Jean-François
Raskin et al., vol. 13660, Springer Nature Switzerland, 2022, pp. 292–305, doi:10.1007/978-3-031-22337-2_14.
short: M. Henzinger, in:, J.-F. Raskin, K. Chatterjee, L. Doyen, R. Majumdar (Eds.),
Principles of Systems Design, Springer Nature Switzerland, Cham, 2022, pp. 292–305.
date_created: 2025-07-22T06:19:50Z
date_published: 2022-12-29T00:00:00Z
date_updated: 2025-07-22T06:23:55Z
day: '29'
doi: 10.1007/978-3-031-22337-2_14
editor:
- first_name: Jean-François
full_name: Raskin, Jean-François
last_name: Raskin
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Laurent
full_name: Doyen, Laurent
last_name: Doyen
- first_name: Rupak
full_name: Majumdar, Rupak
last_name: Majumdar
extern: '1'
intvolume: ' 13660'
language:
- iso: eng
month: '12'
oa_version: None
page: 292-305
place: Cham
publication: Principles of Systems Design
publication_identifier:
eisbn:
- '9783031223372'
eissn:
- 1611-3349
isbn:
- '9783031223365'
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature Switzerland
quality_controlled: '1'
scopus_import: '1'
series_title: LNCS
status: public
title: Fine-Grained Complexity Lower Bounds for Problems in Computer Aided Verification
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 13660
year: '2022'
...
---
OA_place: repository
OA_type: green
_id: '20616'
abstract:
- lang: eng
text: We establish two WDVV-style relations for the disk invariants of real symplectic
fourfolds by implementing Georgieva’s suggestion to lift homology relations from
the Deligne–Mumford moduli spaces of stable real curves. This is accomplished
by lifting judiciously chosen cobordisms realizing these relations. The resulting
lifted relations lead to the recursions for Welschinger invariants announced by
Solomon in 2007 and have the same structure as his WDVV-style relations, but differ
by signs from the latter. Our topological approach provides a general framework
for lifting relations via morphisms between not necessarily orientable spaces.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Xujia
full_name: Chen, Xujia
id: 968ad14a-fd86-11ee-a420-ea29715511a3
last_name: Chen
citation:
ama: Chen X. Steenrod pseudocycles, lifted cobordisms, and Solomon’s relations for
Welschinger invariants. Geometric and Functional Analysis. 2022;32(3):490-567.
doi:10.1007/s00039-022-00596-6
apa: Chen, X. (2022). Steenrod pseudocycles, lifted cobordisms, and Solomon’s relations
for Welschinger invariants. Geometric and Functional Analysis. Springer
Nature. https://doi.org/10.1007/s00039-022-00596-6
chicago: Chen, Xujia. “Steenrod Pseudocycles, Lifted Cobordisms, and Solomon’s Relations
for Welschinger Invariants.” Geometric and Functional Analysis. Springer
Nature, 2022. https://doi.org/10.1007/s00039-022-00596-6.
ieee: X. Chen, “Steenrod pseudocycles, lifted cobordisms, and Solomon’s relations
for Welschinger invariants,” Geometric and Functional Analysis, vol. 32,
no. 3. Springer Nature, pp. 490–567, 2022.
ista: Chen X. 2022. Steenrod pseudocycles, lifted cobordisms, and Solomon’s relations
for Welschinger invariants. Geometric and Functional Analysis. 32(3), 490–567.
mla: Chen, Xujia. “Steenrod Pseudocycles, Lifted Cobordisms, and Solomon’s Relations
for Welschinger Invariants.” Geometric and Functional Analysis, vol. 32,
no. 3, Springer Nature, 2022, pp. 490–567, doi:10.1007/s00039-022-00596-6.
short: X. Chen, Geometric and Functional Analysis 32 (2022) 490–567.
date_created: 2025-11-10T08:40:40Z
date_published: 2022-04-15T00:00:00Z
date_updated: 2025-11-10T15:18:07Z
day: '15'
doi: 10.1007/s00039-022-00596-6
extern: '1'
external_id:
arxiv:
- '1809.08919'
intvolume: ' 32'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.1809.08919
month: '04'
oa: 1
oa_version: Preprint
page: 490-567
publication: Geometric and Functional Analysis
publication_identifier:
eissn:
- 1420-8970
issn:
- 1016-443X
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Steenrod pseudocycles, lifted cobordisms, and Solomon’s relations for Welschinger
invariants
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 32
year: '2022'
...
---
OA_place: repository
OA_type: green
_id: '20617'
abstract:
- lang: eng
text: Our previous paper describes a geometric translation of the construction of
open Gromov–Witten invariants by Solomon and Tukachinsky from a perspective of
$A_{\infty }$-algebras of differential forms. We now use this geometric perspective
to show that these invariants reduce to Welschinger’s open Gromov–Witten invariants
in dimension 6, inline with their and Tian’s expectations. As an immediate corollary,
we obtain a translation of Solomon–Tukachinsky’s open WDVV equations into relations
for Welschinger’s invariants.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Xujia
full_name: Chen, Xujia
id: 968ad14a-fd86-11ee-a420-ea29715511a3
last_name: Chen
citation:
ama: Chen X. Solomon-Tukachinsky’s versus Welschinger’s open Gromov-Witten invariants
of symplectic six-folds. International Mathematics Research Notices. 2022;2022(9):7021-7055.
doi:10.1093/imrn/rnaa318
apa: Chen, X. (2022). Solomon-Tukachinsky’s versus Welschinger’s open Gromov-Witten
invariants of symplectic six-folds. International Mathematics Research Notices.
Oxford University Press. https://doi.org/10.1093/imrn/rnaa318
chicago: Chen, Xujia. “Solomon-Tukachinsky’s versus Welschinger’s Open Gromov-Witten
Invariants of Symplectic Six-Folds.” International Mathematics Research Notices.
Oxford University Press, 2022. https://doi.org/10.1093/imrn/rnaa318.
ieee: X. Chen, “Solomon-Tukachinsky’s versus Welschinger’s open Gromov-Witten invariants
of symplectic six-folds,” International Mathematics Research Notices, vol.
2022, no. 9. Oxford University Press, pp. 7021–7055, 2022.
ista: Chen X. 2022. Solomon-Tukachinsky’s versus Welschinger’s open Gromov-Witten
invariants of symplectic six-folds. International Mathematics Research Notices.
2022(9), 7021–7055.
mla: Chen, Xujia. “Solomon-Tukachinsky’s versus Welschinger’s Open Gromov-Witten
Invariants of Symplectic Six-Folds.” International Mathematics Research Notices,
vol. 2022, no. 9, Oxford University Press, 2022, pp. 7021–55, doi:10.1093/imrn/rnaa318.
short: X. Chen, International Mathematics Research Notices 2022 (2022) 7021–7055.
date_created: 2025-11-10T08:40:57Z
date_published: 2022-05-01T00:00:00Z
date_updated: 2025-11-10T14:57:33Z
day: '01'
doi: 10.1093/imrn/rnaa318
extern: '1'
external_id:
arxiv:
- '1912.05437'
intvolume: ' 2022'
issue: '9'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.1912.05437
month: '05'
oa: 1
oa_version: Preprint
page: 7021-7055
publication: International Mathematics Research Notices
publication_identifier:
eissn:
- 1687-0247
issn:
- 1073-7928
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Solomon-Tukachinsky’s versus Welschinger’s open Gromov-Witten invariants of
symplectic six-folds
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2022
year: '2022'
...
---
OA_place: repository
OA_type: green
_id: '20620'
abstract:
- lang: eng
text: The 2016 papers of J. Solomon and S. Tukachinsky use bounding chains in Fukaya's
$A_{\infty}$-algebras to define numerical disk counts relative to a Lagrangian
under certain regularity assumptions on the moduli spaces of disks. We present
a (self-contained) direct geometric analogue of their construction under weaker
topological assumptions, extend it over arbitrary rings in the process, and sketch
an extension without any assumptions over rings containing the rationals. This
implements the intuitive suggestion represented by their drawing and P. Georgieva's
perspective. We also note a curious relation for the standard Gromov-Witten invariants
readily deducible from their work. In a sequel, we use the geometric perspective
of this paper to relate Solomon-Tukachinsky's invariants to Welschinger's open
invariants of symplectic sixfolds, confirming their belief and G. Tian's related
expectation concerning K. Fukaya's earlier construction.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Xujia
full_name: Chen, Xujia
id: 968ad14a-fd86-11ee-a420-ea29715511a3
last_name: Chen
citation:
ama: Chen X. A geometric depiction of Solomon-Tukachinsky’s construction of open
GW-invariants. Peking Mathematical Journal . 2022;5:279-348. doi:10.1007/s42543-021-00044-8
apa: Chen, X. (2022). A geometric depiction of Solomon-Tukachinsky’s construction
of open GW-invariants. Peking Mathematical Journal . Springer Nature. https://doi.org/10.1007/s42543-021-00044-8
chicago: Chen, Xujia. “A Geometric Depiction of Solomon-Tukachinsky’s Construction
of Open GW-Invariants.” Peking Mathematical Journal . Springer Nature,
2022. https://doi.org/10.1007/s42543-021-00044-8.
ieee: X. Chen, “A geometric depiction of Solomon-Tukachinsky’s construction of open
GW-invariants,” Peking Mathematical Journal , vol. 5. Springer Nature,
pp. 279–348, 2022.
ista: Chen X. 2022. A geometric depiction of Solomon-Tukachinsky’s construction
of open GW-invariants. Peking Mathematical Journal . 5, 279–348.
mla: Chen, Xujia. “A Geometric Depiction of Solomon-Tukachinsky’s Construction of
Open GW-Invariants.” Peking Mathematical Journal , vol. 5, Springer Nature,
2022, pp. 279–348, doi:10.1007/s42543-021-00044-8.
short: X. Chen, Peking Mathematical Journal 5 (2022) 279–348.
date_created: 2025-11-10T08:43:20Z
date_published: 2022-09-01T00:00:00Z
date_updated: 2025-11-10T13:51:17Z
day: '01'
doi: 10.1007/s42543-021-00044-8
extern: '1'
external_id:
arxiv:
- '1912.04119'
intvolume: ' 5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.1912.04119
month: '09'
oa: 1
oa_version: Submitted Version
page: 279-348
publication: 'Peking Mathematical Journal '
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: A geometric depiction of Solomon-Tukachinsky's construction of open GW-invariants
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2022'
...
---
_id: '20627'
abstract:
- lang: eng
text: The modern control model of the two-wheeled balancing vehicle is established
by rational simplification and linearization and selection of appropriate state
space variables. The state space expressions in modern control theory are used
to make up for some deficiencies in the classical inverted pendulum model. By
constructing the mathematical model of the LQR controller in MATLAB, using Simulink
for model design and theoretical simulation analysis according to the actual application
scenario, the results show that the improved LQR controller can be used in the
autonomous balance control and anti-external interference of the two-wheeled self-balancing
vehicle model. Has excellent performance.
acknowledgement: 'This work was supported by the Nanchong City School-Science and
Technology Strategic Cooperation Project: Research on autonomous navigation technology
of mobile robot based on visual SLAM in indoor environment(SXQHJH025); Key technologies
for safety inspection of intelligent vehicles in oil and gas chemical production
workshops research and design (19SXHZ0022).'
article_processing_charge: No
author:
- first_name: Jiemin
full_name: Yuan, Jiemin
last_name: Yuan
- first_name: Haiyun
full_name: Chen, Haiyun
last_name: Chen
- first_name: Tao
full_name: Yong, Tao
last_name: Yong
- first_name: Xi
full_name: Lai, Xi
last_name: Lai
- first_name: Xujia
full_name: Chen, Xujia
id: 968ad14a-fd86-11ee-a420-ea29715511a3
last_name: Chen
citation:
ama: 'Yuan J, Chen H, Yong T, Lai X, Chen X. Research on two-wheeled balance car
based on improved LQR controller. In: 6th Advanced Information Technology,
Electronic and Automation Control Conference. IEEE; 2022. doi:10.1109/iaeac54830.2022.9930026'
apa: 'Yuan, J., Chen, H., Yong, T., Lai, X., & Chen, X. (2022). Research on
two-wheeled balance car based on improved LQR controller. In 6th Advanced Information
Technology, Electronic and Automation Control Conference. Beijing, China:
IEEE. https://doi.org/10.1109/iaeac54830.2022.9930026'
chicago: Yuan, Jiemin, Haiyun Chen, Tao Yong, Xi Lai, and Xujia Chen. “Research
on Two-Wheeled Balance Car Based on Improved LQR Controller.” In 6th Advanced
Information Technology, Electronic and Automation Control Conference. IEEE,
2022. https://doi.org/10.1109/iaeac54830.2022.9930026.
ieee: J. Yuan, H. Chen, T. Yong, X. Lai, and X. Chen, “Research on two-wheeled balance
car based on improved LQR controller,” in 6th Advanced Information Technology,
Electronic and Automation Control Conference, Beijing, China, 2022.
ista: 'Yuan J, Chen H, Yong T, Lai X, Chen X. 2022. Research on two-wheeled balance
car based on improved LQR controller. 6th Advanced Information Technology, Electronic
and Automation Control Conference. IAEAC: Advanced Information Technology, Electronic
and Automation Control Conference.'
mla: Yuan, Jiemin, et al. “Research on Two-Wheeled Balance Car Based on Improved
LQR Controller.” 6th Advanced Information Technology, Electronic and Automation
Control Conference, IEEE, 2022, doi:10.1109/iaeac54830.2022.9930026.
short: J. Yuan, H. Chen, T. Yong, X. Lai, X. Chen, in:, 6th Advanced Information
Technology, Electronic and Automation Control Conference, IEEE, 2022.
conference:
end_date: 2022-10-05
location: Beijing, China
name: 'IAEAC: Advanced Information Technology, Electronic and Automation Control
Conference'
start_date: 2022-10-03
date_created: 2025-11-10T08:52:47Z
date_published: 2022-11-09T00:00:00Z
date_updated: 2025-11-10T14:53:37Z
day: '09'
doi: 10.1109/iaeac54830.2022.9930026
extern: '1'
language:
- iso: eng
month: '11'
oa_version: None
publication: 6th Advanced Information Technology, Electronic and Automation Control
Conference
publication_identifier:
eisbn:
- '9781665458641'
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: Research on two-wheeled balance car based on improved LQR controller
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2022'
...
---
OA_place: repository
OA_type: green
_id: '20763'
abstract:
- lang: eng
text: Compared with peripheral late-stage transformations mainly focusing on carbon–hydrogen
functionalizations, reliable strategies to directly edit the core skeleton of
pharmaceutical lead compounds still remain scarce despite the recent flurry of
activity in this area. Herein, we report the skeletal editing of indoles through
nitrogen atom insertion, accessing the corresponding quinazoline or quinoxaline
bioisosteres by trapping of an electrophilic nitrene species generated from ammonium
carbamate and hypervalent iodine. This reactivity relies on the strategic use
of a silyl group as a labile protecting group that can facilitate subsequent product
release. The utility of this highly functional group-compatible methodology in
the context of late-stage skeletal editing of several commercial drugs is demonstrated.
article_processing_charge: No
article_type: original
author:
- first_name: Julia
full_name: Reisenbauer, Julia
id: 51d862e9-36ee-11f0-86d3-8534c85a5496
last_name: Reisenbauer
- first_name: Ori
full_name: Green, Ori
last_name: Green
- first_name: Allegra
full_name: Franchino, Allegra
last_name: Franchino
- first_name: Patrick
full_name: Finkelstein, Patrick
last_name: Finkelstein
- first_name: Bill
full_name: Morandi, Bill
last_name: Morandi
citation:
ama: Reisenbauer J, Green O, Franchino A, Finkelstein P, Morandi B. Late-stage diversification
of indole skeletons through nitrogen atom insertion. Science. 2022;377(6610):1104-1109.
doi:10.1126/science.add1383
apa: Reisenbauer, J., Green, O., Franchino, A., Finkelstein, P., & Morandi,
B. (2022). Late-stage diversification of indole skeletons through nitrogen atom
insertion. Science. American Association for the Advancement of Science.
https://doi.org/10.1126/science.add1383
chicago: Reisenbauer, Julia, Ori Green, Allegra Franchino, Patrick Finkelstein,
and Bill Morandi. “Late-Stage Diversification of Indole Skeletons through Nitrogen
Atom Insertion.” Science. American Association for the Advancement of Science,
2022. https://doi.org/10.1126/science.add1383.
ieee: J. Reisenbauer, O. Green, A. Franchino, P. Finkelstein, and B. Morandi, “Late-stage
diversification of indole skeletons through nitrogen atom insertion,” Science,
vol. 377, no. 6610. American Association for the Advancement of Science, pp. 1104–1109,
2022.
ista: Reisenbauer J, Green O, Franchino A, Finkelstein P, Morandi B. 2022. Late-stage
diversification of indole skeletons through nitrogen atom insertion. Science.
377(6610), 1104–1109.
mla: Reisenbauer, Julia, et al. “Late-Stage Diversification of Indole Skeletons
through Nitrogen Atom Insertion.” Science, vol. 377, no. 6610, American
Association for the Advancement of Science, 2022, pp. 1104–09, doi:10.1126/science.add1383.
short: J. Reisenbauer, O. Green, A. Franchino, P. Finkelstein, B. Morandi, Science
377 (2022) 1104–1109.
date_created: 2025-12-09T14:24:37Z
date_published: 2022-09-01T00:00:00Z
date_updated: 2025-12-16T11:59:34Z
day: '01'
doi: 10.1126/science.add1383
extern: '1'
external_id:
pmid:
- '36048958'
intvolume: ' 377'
issue: '6610'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: 10.26434/chemrxiv-2022-jvfxw
month: '09'
oa: 1
oa_version: Preprint
page: 1104-1109
pmid: 1
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Late-stage diversification of indole skeletons through nitrogen atom insertion
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 377
year: '2022'
...
---
OA_place: repository
OA_type: green
_id: '20764'
abstract:
- lang: eng
text: Hydrocyanation reactions enable access to synthetically valuable nitriles
from readily available alkene precursors. However, hydrocyanation reactions using
hydrogen cyanide (HCN) or similarly toxic reagents on laboratory scale can be
particularly challenging due to their hazardous nature. In addition, such processes
typically require air- and temperature-sensitive Ni(0) precatalysts, further reducing
the operational simplicity of this transformation. Herein, we report a HCN-free
transfer hydrocyanation of alkenes and alkynes that employs commercially available
aliphatic nitriles as sacrificial HCN donors in combination with a catalytic amount
of air-stable and inexpensive NiCl2 as a precatalyst and a cocatalytic Lewis acid.
The scalability and robustness of the catalytic process were demonstrated by the
hydrocyanation of α-methylstyrene on a 100 mmol scale (11.4 g of product obtained)
using 1 mol % of the Ni catalyst. In addition, the feasibility of the dehydrocyanation
protocol using the air-stable Ni(II) precatalyst and norbornadiene as a sacrificial
acceptor was showcased by the selective conversion of an aliphatic nitrile into
the corresponding alkene.
article_processing_charge: No
article_type: original
author:
- first_name: Julia
full_name: Reisenbauer, Julia
id: 51d862e9-36ee-11f0-86d3-8534c85a5496
last_name: Reisenbauer
- first_name: Benjamin N.
full_name: Bhawal, Benjamin N.
last_name: Bhawal
- first_name: Nicola
full_name: Jelmini, Nicola
last_name: Jelmini
- first_name: Bill
full_name: Morandi, Bill
last_name: Morandi
citation:
ama: Reisenbauer J, Bhawal BN, Jelmini N, Morandi B. Development of an operationally
simple, scalable, and HCN-free transfer hydrocyanation protocol using an air-stable
nickel precatalyst. Organic Process Research & Development. 2022;26(4):1165-1173.
doi:10.1021/acs.oprd.1c00442
apa: Reisenbauer, J., Bhawal, B. N., Jelmini, N., & Morandi, B. (2022). Development
of an operationally simple, scalable, and HCN-free transfer hydrocyanation protocol
using an air-stable nickel precatalyst. Organic Process Research & Development.
American Chemical Society. https://doi.org/10.1021/acs.oprd.1c00442
chicago: Reisenbauer, Julia, Benjamin N. Bhawal, Nicola Jelmini, and Bill Morandi.
“Development of an Operationally Simple, Scalable, and HCN-Free Transfer Hydrocyanation
Protocol Using an Air-Stable Nickel Precatalyst.” Organic Process Research
& Development. American Chemical Society, 2022. https://doi.org/10.1021/acs.oprd.1c00442.
ieee: J. Reisenbauer, B. N. Bhawal, N. Jelmini, and B. Morandi, “Development of
an operationally simple, scalable, and HCN-free transfer hydrocyanation protocol
using an air-stable nickel precatalyst,” Organic Process Research & Development,
vol. 26, no. 4. American Chemical Society, pp. 1165–1173, 2022.
ista: Reisenbauer J, Bhawal BN, Jelmini N, Morandi B. 2022. Development of an operationally
simple, scalable, and HCN-free transfer hydrocyanation protocol using an air-stable
nickel precatalyst. Organic Process Research & Development. 26(4), 1165–1173.
mla: Reisenbauer, Julia, et al. “Development of an Operationally Simple, Scalable,
and HCN-Free Transfer Hydrocyanation Protocol Using an Air-Stable Nickel Precatalyst.”
Organic Process Research & Development, vol. 26, no. 4, American Chemical
Society, 2022, pp. 1165–73, doi:10.1021/acs.oprd.1c00442.
short: J. Reisenbauer, B.N. Bhawal, N. Jelmini, B. Morandi, Organic Process Research
& Development 26 (2022) 1165–1173.
date_created: 2025-12-09T14:24:58Z
date_published: 2022-02-15T00:00:00Z
date_updated: 2025-12-16T12:02:59Z
day: '15'
doi: 10.1021/acs.oprd.1c00442
extern: '1'
intvolume: ' 26'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.research-collection.ethz.ch/entities/publication/4ed5123f-eb11-4a4d-b06c-f50edcec38b8
month: '02'
oa: 1
oa_version: Submitted Version
page: 1165-1173
publication: Organic Process Research & Development
publication_identifier:
eissn:
- 1520-586X
issn:
- 1083-6160
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Development of an operationally simple, scalable, and HCN-free transfer hydrocyanation
protocol using an air-stable nickel precatalyst
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 26
year: '2022'
...
---
_id: '10016'
abstract:
- lang: eng
text: 'Auxin has always been at the forefront of research in plant physiology and
development. Since the earliest contemplations by Julius von Sachs and Charles
Darwin, more than a century-long struggle has been waged to understand its function.
This largely reflects the failures, successes, and inevitable progress in the
entire field of plant signaling and development. Here I present 14 stations on
our long and sometimes mystical journey to understand auxin. These highlights
were selected to give a flavor of the field and to show the scope and limits of
our current knowledge. A special focus is put on features that make auxin unique
among phytohormones, such as its dynamic, directional transport network, which
integrates external and internal signals, including self-organizing feedback.
Accented are persistent mysteries and controversies. The unexpected discoveries
related to rapid auxin responses and growth regulation recently disturbed our
contentment regarding understanding of the auxin signaling mechanism. These new
revelations, along with advances in technology, usher us into a new, exciting
era in auxin research. '
acknowledgement: "The author thanks the whole community of researchers consciously
or unconsciously working on questions related to auxin, whose hard work and enthusiasm
contributed to development of this exciting story. Particular thanks go to many\r\nbrilliant
present and past members of the Friml group and our numerous excellent collaborators,
without whom my own personal journey would not be possible. The way of the cross
with its 14 stations is a popular devotion among Roman Catholics and inspires them
to make a spiritual pilgrimage through contemplation of Christ on his last day.
Its aspects of gradual progress, struggle, passion, and revelation served as an
inspiration for the formal depiction of our journey to understanding auxin as described
in this review. It is in no way intended to reflect the personal beliefs of the
author and readers. I am grateful to Nick Barton, Eva Benková, Lenka Caisová, Matyáš
Fendrych, Lukáš Fiedler, Monika Frátriková, Jarmila Frimlová, Michelle Gallei, Jakub
Hajný, Lukas Hoermayer, Alexandra Mally, Ondrˇej Novák, Jan Petrášek, Aleš Pěnčík,
Steffen Vanneste, Tongda Xu, and Zhenbiao Yang for their valuable comments. Special
thanks go to Michelle Gallei for her invaluable assistance with the figures."
article_number: a039859
article_processing_charge: No
article_type: review
author:
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Friml J. Fourteen stations of auxin. Cold Spring Harbor Perspectives in
Biology. 2022;14(5). doi:10.1101/cshperspect.a039859
apa: Friml, J. (2022). Fourteen stations of auxin. Cold Spring Harbor Perspectives
in Biology. Cold Spring Harbor Laboratory Press. https://doi.org/10.1101/cshperspect.a039859
chicago: Friml, Jiří. “Fourteen Stations of Auxin.” Cold Spring Harbor Perspectives
in Biology. Cold Spring Harbor Laboratory Press, 2022. https://doi.org/10.1101/cshperspect.a039859.
ieee: J. Friml, “Fourteen stations of auxin,” Cold Spring Harbor Perspectives
in Biology, vol. 14, no. 5. Cold Spring Harbor Laboratory Press, 2022.
ista: Friml J. 2022. Fourteen stations of auxin. Cold Spring Harbor Perspectives
in Biology. 14(5), a039859.
mla: Friml, Jiří. “Fourteen Stations of Auxin.” Cold Spring Harbor Perspectives
in Biology, vol. 14, no. 5, a039859, Cold Spring Harbor Laboratory Press,
2022, doi:10.1101/cshperspect.a039859.
short: J. Friml, Cold Spring Harbor Perspectives in Biology 14 (2022).
corr_author: '1'
date_created: 2021-09-14T11:36:53Z
date_published: 2022-05-27T00:00:00Z
date_updated: 2026-06-18T08:35:48Z
day: '27'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1101/cshperspect.a039859
external_id:
isi:
- '000806563000003'
pmid:
- '34400554'
intvolume: ' 14'
isi: 1
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: 'https://doi.org/10.1101/cshperspect.a039859 '
month: '05'
oa: 1
oa_version: Published Version
pmid: 1
publication: Cold Spring Harbor Perspectives in Biology
publication_identifier:
issn:
- 1943-0264
publication_status: published
publisher: Cold Spring Harbor Laboratory Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Fourteen stations of auxin
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 14
year: '2022'
...
---
_id: '10181'
abstract:
- lang: eng
text: In this article we study some geometric properties of proximally smooth sets.
First, we introduce a modification of the metric projection and prove its existence.
Then we provide an algorithm for constructing a rectifiable curve between two
sufficiently close points of a proximally smooth set in a uniformly convex and
uniformly smooth Banach space, with the moduli of smoothness and convexity of
power type. Our algorithm returns a reasonably short curve between two sufficiently
close points of a proximally smooth set, is iterative and uses our modification
of the metric projection. We estimate the length of the constructed curve and
its deviation from the segment with the same endpoints. These estimates coincide
up to a constant factor with those for the geodesics in a proximally smooth set
in a Hilbert space.
acknowledgement: Theorem 2 was obtained at Steklov Mathematical Institute RAS and
supported by Russian Science Foundation, grant N 19-11-00087.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Grigory
full_name: Ivanov, Grigory
id: 87744F66-5C6F-11EA-AFE0-D16B3DDC885E
last_name: Ivanov
orcid: 0000-0002-5021-3982
- first_name: Mariana S.
full_name: Lopushanski, Mariana S.
last_name: Lopushanski
citation:
ama: Ivanov G, Lopushanski MS. Rectifiable curves in proximally smooth sets. Set-Valued
and Variational Analysis. 2022;30(2):657-675. doi:10.1007/s11228-021-00612-1
apa: Ivanov, G., & Lopushanski, M. S. (2022). Rectifiable curves in proximally
smooth sets. Set-Valued and Variational Analysis. Springer Nature. https://doi.org/10.1007/s11228-021-00612-1
chicago: Ivanov, Grigory, and Mariana S. Lopushanski. “Rectifiable Curves in Proximally
Smooth Sets.” Set-Valued and Variational Analysis. Springer Nature, 2022.
https://doi.org/10.1007/s11228-021-00612-1.
ieee: G. Ivanov and M. S. Lopushanski, “Rectifiable curves in proximally smooth
sets,” Set-Valued and Variational Analysis, vol. 30, no. 2. Springer Nature,
pp. 657–675, 2022.
ista: Ivanov G, Lopushanski MS. 2022. Rectifiable curves in proximally smooth sets.
Set-Valued and Variational Analysis. 30(2), 657–675.
mla: Ivanov, Grigory, and Mariana S. Lopushanski. “Rectifiable Curves in Proximally
Smooth Sets.” Set-Valued and Variational Analysis, vol. 30, no. 2, Springer
Nature, 2022, pp. 657–75, doi:10.1007/s11228-021-00612-1.
short: G. Ivanov, M.S. Lopushanski, Set-Valued and Variational Analysis 30 (2022)
657–675.
date_created: 2021-10-24T22:01:35Z
date_published: 2022-06-01T00:00:00Z
date_updated: 2026-06-18T08:36:30Z
day: '01'
ddc:
- '500'
department:
- _id: UlWa
doi: 10.1007/s11228-021-00612-1
external_id:
arxiv:
- '2012.10691'
isi:
- '000705774800001'
intvolume: ' 30'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/2012.10691
month: '06'
oa: 1
oa_version: Published Version
page: 657-675
publication: Set-Valued and Variational Analysis
publication_identifier:
eissn:
- 1877-0541
issn:
- 0927-6947
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Rectifiable curves in proximally smooth sets
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 30
year: '2022'
...
---
_id: '10182'
abstract:
- lang: eng
text: The mitochondrial oxidative phosphorylation system is central to cellular
metabolism. It comprises five enzymatic complexes and two mobile electron carriers
that work in a mitochondrial respiratory chain. By coupling the oxidation of reducing
equivalents coming into mitochondria to the generation and subsequent dissipation
of a proton gradient across the inner mitochondrial membrane, this electron transport
chain drives the production of ATP, which is then used as a primary energy carrier
in virtually all cellular processes. Minimal perturbations of the respiratory
chain activity are linked to diseases; therefore, it is necessary to understand
how these complexes are assembled and regulated and how they function. In this
Review, we outline the latest assembly models for each individual complex, and
we also highlight the recent discoveries indicating that the formation of larger
assemblies, known as respiratory supercomplexes, originates from the association
of the intermediates of individual complexes. We then discuss how recent cryo-electron
microscopy structures have been key to answering open questions on the function
of the electron transport chain in mitochondrial respiration and how supercomplexes
and other factors, including metabolites, can regulate the activity of the single
complexes. When relevant, we discuss how these mechanisms contribute to physiology
and outline their deregulation in human diseases.
article_processing_charge: No
article_type: original
author:
- first_name: Irene
full_name: Vercellino, Irene
id: 3ED6AF16-F248-11E8-B48F-1D18A9856A87
last_name: Vercellino
orcid: ' 0000-0001-5618-3449'
- first_name: Leonid A
full_name: Sazanov, Leonid A
id: 338D39FE-F248-11E8-B48F-1D18A9856A87
last_name: Sazanov
orcid: 0000-0002-0977-7989
citation:
ama: Vercellino I, Sazanov LA. The assembly, regulation and function of the mitochondrial
respiratory chain. Nature Reviews Molecular Cell Biology. 2022;23:141–161.
doi:10.1038/s41580-021-00415-0
apa: Vercellino, I., & Sazanov, L. A. (2022). The assembly, regulation and function
of the mitochondrial respiratory chain. Nature Reviews Molecular Cell Biology.
Springer Nature. https://doi.org/10.1038/s41580-021-00415-0
chicago: Vercellino, Irene, and Leonid A Sazanov. “The Assembly, Regulation and
Function of the Mitochondrial Respiratory Chain.” Nature Reviews Molecular
Cell Biology. Springer Nature, 2022. https://doi.org/10.1038/s41580-021-00415-0.
ieee: I. Vercellino and L. A. Sazanov, “The assembly, regulation and function of
the mitochondrial respiratory chain,” Nature Reviews Molecular Cell Biology,
vol. 23. Springer Nature, pp. 141–161, 2022.
ista: Vercellino I, Sazanov LA. 2022. The assembly, regulation and function of the
mitochondrial respiratory chain. Nature Reviews Molecular Cell Biology. 23, 141–161.
mla: Vercellino, Irene, and Leonid A. Sazanov. “The Assembly, Regulation and Function
of the Mitochondrial Respiratory Chain.” Nature Reviews Molecular Cell Biology,
vol. 23, Springer Nature, 2022, pp. 141–161, doi:10.1038/s41580-021-00415-0.
short: I. Vercellino, L.A. Sazanov, Nature Reviews Molecular Cell Biology 23 (2022)
141–161.
corr_author: '1'
date_created: 2021-10-24T22:01:35Z
date_published: 2022-02-01T00:00:00Z
date_updated: 2024-10-09T21:01:03Z
day: '01'
department:
- _id: LeSa
doi: 10.1038/s41580-021-00415-0
external_id:
isi:
- '000705697100001'
pmid:
- '34621061'
intvolume: ' 23'
isi: 1
language:
- iso: eng
month: '02'
oa_version: None
page: 141–161
pmid: 1
publication: Nature Reviews Molecular Cell Biology
publication_identifier:
eissn:
- 1471-0080
issn:
- 1471-0072
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: The assembly, regulation and function of the mitochondrial respiratory chain
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 23
year: '2022'
...