---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20143'
abstract:
- lang: eng
text: Bacteria and archaea deploy diverse antiviral defense systems, many of which
remain mechanistically uncharacterized. Here, we characterize Kiwa, a widespread
two-component system composed of the transmembrane sensor KwaA and the DNA-binding
effector KwaB. Cryogenic electron microscopy (cryo-EM) analysis reveals that KwaA
and KwaB assemble into a large, membrane-associated supercomplex. Upon phage binding,
KwaA senses infection at the membrane, leading to KwaB binding of ejected phage
DNA and inhibition of replication and late transcription, without inducing host
cell death. Although KwaB can bind DNA independently, its antiviral activity requires
association with KwaA, suggesting spatial or conformational regulation. We show
that the phage-encoded DNA-mimic protein Gam directly binds and inhibits KwaB
but that co-expression with the Gam-targeted RecBCD system restores protection
by Kiwa. Our findings support a model in which Kiwa coordinates membrane-associated
detection of phage infection with downstream DNA binding by its effector, forming
a spatially coordinated antiviral mechanism.
acknowledgement: We thank Rotem Sorek (Weizmann Institute of Science) for the Lambda
Gam mutant and Ian Molineux (University of Texas) for T4Δgp2. We thank You Yu (Zhejiang
University-University of Edinburgh Institute) and J. De La Cruz (MSK) for assistance
with cryo-EM data collection and Lyuqin Zheng (MSK) for discussions on structural
analysis. We thank the Imaging and Microscopy Centre (IMC) at the University of
Southampton. This work was supported by Royal Society grant RGS\R2\222312 to F.L.N.;
Welch Foundation grant F-1938 and National Institutes of Health R35GM138348 to D.W.T.;
Wessex Medical Research Innovation grant AE06 to T.A.; and NIH grant GM145888 and
Maloris Foundation and Memorial Sloan-Kettering Core grant (P30-CA008748) to D.J.P.
In addition to MSKCC cryo-EM resources, some of this work was performed at the National
Center for CryoEM Access and Training (NCCAT) and the Simons Electron Microscopy
Center located at the New York Structural Biology Center, supported by the NIH Common
Fund Transformative High Resolution Cryo-Electron Microscopy program (U24 GM129539)
and Simons Foundation (SF349247) and NY State Assembly grants. This research used
NSLS-II MX X-ray User Resources (FMX) of the National Synchrotron Light Source II,
operated for the DOE Office of Science by Brookhaven National Laboratory under contract
no. DE-SC0012704. The Center for BioMolecular Structure (CBMS) is primarily supported
by the NIH, the National Institute of General Medical Sciences (NIGMS) through a
Center Core P30 Grant (P30GM133893), and by the DOE Office of Biological and Environmental
Research (KP1605010). R.K. and E.V.K. are supported by the Intramural Research Program
of the NIH (National Library of Medicine).
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Zhiying
full_name: Zhang, Zhiying
last_name: Zhang
- first_name: Thomas C.
full_name: Todeschini, Thomas C.
last_name: Todeschini
- first_name: Yi
full_name: Wu, Yi
last_name: Wu
- first_name: Roman
full_name: Kogay, Roman
last_name: Kogay
- first_name: Ameena
full_name: Naji, Ameena
last_name: Naji
- first_name: Joaquin
full_name: Cardenas Rodriguez, Joaquin
last_name: Cardenas Rodriguez
- first_name: Rupavidhya
full_name: Mondi, Rupavidhya
last_name: Mondi
- first_name: Daniel
full_name: Kaganovich, Daniel
last_name: Kaganovich
- first_name: David W.
full_name: Taylor, David W.
last_name: Taylor
- first_name: Jack Peter Kelly
full_name: Bravo, Jack Peter Kelly
id: 96aecfa5-8931-11ee-af30-aa6a5d6eee0e
last_name: Bravo
orcid: 0000-0003-0456-0753
- first_name: Marianna
full_name: Teplova, Marianna
last_name: Teplova
- first_name: Triana
full_name: Amen, Triana
last_name: Amen
- first_name: Eugene
full_name: Koonin, Eugene
last_name: Koonin
- first_name: Dinshaw J.
full_name: Patel, Dinshaw J.
last_name: Patel
- first_name: Franklin L.
full_name: Nobrega, Franklin L.
last_name: Nobrega
citation:
ama: Zhang Z, Todeschini TC, Wu Y, et al. Kiwa is a membrane-embedded defense supercomplex
activated at phage attachment sites. Cell. 2025;188(21):5862-5877.e23.
doi:10.1016/j.cell.2025.07.002
apa: Zhang, Z., Todeschini, T. C., Wu, Y., Kogay, R., Naji, A., Cardenas Rodriguez,
J., … Nobrega, F. L. (2025). Kiwa is a membrane-embedded defense supercomplex
activated at phage attachment sites. Cell. Elsevier. https://doi.org/10.1016/j.cell.2025.07.002
chicago: Zhang, Zhiying, Thomas C. Todeschini, Yi Wu, Roman Kogay, Ameena Naji,
Joaquin Cardenas Rodriguez, Rupavidhya Mondi, et al. “Kiwa Is a Membrane-Embedded
Defense Supercomplex Activated at Phage Attachment Sites.” Cell. Elsevier,
2025. https://doi.org/10.1016/j.cell.2025.07.002.
ieee: Z. Zhang et al., “Kiwa is a membrane-embedded defense supercomplex
activated at phage attachment sites,” Cell, vol. 188, no. 21. Elsevier,
p. 5862–5877.e23, 2025.
ista: Zhang Z, Todeschini TC, Wu Y, Kogay R, Naji A, Cardenas Rodriguez J, Mondi
R, Kaganovich D, Taylor DW, Bravo JPK, Teplova M, Amen T, Koonin E, Patel DJ,
Nobrega FL. 2025. Kiwa is a membrane-embedded defense supercomplex activated at
phage attachment sites. Cell. 188(21), 5862–5877.e23.
mla: Zhang, Zhiying, et al. “Kiwa Is a Membrane-Embedded Defense Supercomplex Activated
at Phage Attachment Sites.” Cell, vol. 188, no. 21, Elsevier, 2025, p.
5862–5877.e23, doi:10.1016/j.cell.2025.07.002.
short: Z. Zhang, T.C. Todeschini, Y. Wu, R. Kogay, A. Naji, J. Cardenas Rodriguez,
R. Mondi, D. Kaganovich, D.W. Taylor, J.P.K. Bravo, M. Teplova, T. Amen, E. Koonin,
D.J. Patel, F.L. Nobrega, Cell 188 (2025) 5862–5877.e23.
date_created: 2025-08-07T05:00:04Z
date_published: 2025-10-16T00:00:00Z
date_updated: 2025-12-29T14:15:58Z
day: '16'
ddc:
- '570'
department:
- _id: JaBr
doi: 10.1016/j.cell.2025.07.002
external_id:
isi:
- '001603560700005'
pmid:
- '40730155'
file:
- access_level: open_access
checksum: b944de5fbd7455f58e1ff338ad352239
content_type: application/pdf
creator: dernst
date_created: 2025-12-29T14:15:25Z
date_updated: 2025-12-29T14:15:25Z
file_id: '20875'
file_name: 2025_Cell_Zhang.pdf
file_size: 32104588
relation: main_file
success: 1
file_date_updated: 2025-12-29T14:15:25Z
has_accepted_license: '1'
intvolume: ' 188'
isi: 1
issue: '21'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '10'
oa: 1
oa_version: Published Version
page: 5862-5877.e23
pmid: 1
publication: Cell
publication_identifier:
eissn:
- 1097-4172
issn:
- 0092-8674
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Kiwa is a membrane-embedded defense supercomplex activated at phage attachment
sites
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 188
year: '2025'
...
---
OA_place: publisher
OA_type: gold
_id: '20146'
abstract:
- lang: eng
text: "This criteria catalogue and the accompanying assessment questions were developed
by a working group of KEMÖ (Kooperation E-Medien Österreich, the Austrian Academic
Library Consortium). They are intended to support research institutions and organisations
in the evaluation of Open Science Infrastructures. The 20 criteria outlined in
the catalogue provide a structured basis for making informed decisions regarding
the financial support of these infrastructures.\r\n\r\nThe assessment questions
are intended to be completed by Open Science Infrastructures and can be shared
with them accordingly."
article_processing_charge: No
author:
- first_name: Paul
full_name: Gredler, Paul
last_name: Gredler
- first_name: Christian
full_name: Kaier, Christian
last_name: Kaier
- first_name: Patrick
full_name: Danowski, Patrick
id: 2EBD1598-F248-11E8-B48F-1D18A9856A87
last_name: Danowski
orcid: 0000-0002-6026-4409
- first_name: Michael
full_name: Zoyer, Michael
last_name: Zoyer
- first_name: Katharina
full_name: Rieck, Katharina
last_name: Rieck
- first_name: Andreas
full_name: Ferus, Andreas
last_name: Ferus
- first_name: Elisabeth
full_name: Rosenberger, Elisabeth
last_name: Rosenberger
- first_name: Alexander
full_name: Löffler, Alexander
last_name: Löffler
- first_name: Lisa
full_name: Hofer, Lisa
last_name: Hofer
- first_name: Laura
full_name: Still, Laura
last_name: Still
citation:
ama: Gredler P, Kaier C, Danowski P, et al. Catalogue of Criteria for Assessing
the Funding Eligibility of Open Science Infrastructures. Zenodo; 2025. doi:10.5281/zenodo.15269364
apa: Gredler, P., Kaier, C., Danowski, P., Zoyer, M., Rieck, K., Ferus, A., … Still,
L. (2025). Catalogue of criteria for assessing the funding eligibility of Open
Science infrastructures. Zenodo. https://doi.org/10.5281/zenodo.15269364
chicago: Gredler, Paul, Christian Kaier, Patrick Danowski, Michael Zoyer, Katharina
Rieck, Andreas Ferus, Elisabeth Rosenberger, Alexander Löffler, Lisa Hofer, and
Laura Still. Catalogue of Criteria for Assessing the Funding Eligibility of
Open Science Infrastructures. Zenodo, 2025. https://doi.org/10.5281/zenodo.15269364.
ieee: P. Gredler et al., Catalogue of criteria for assessing the funding
eligibility of Open Science infrastructures. Zenodo, 2025.
ista: Gredler P, Kaier C, Danowski P, Zoyer M, Rieck K, Ferus A, Rosenberger E,
Löffler A, Hofer L, Still L. 2025. Catalogue of criteria for assessing the funding
eligibility of Open Science infrastructures, Zenodo,p.
mla: Gredler, Paul, et al. Catalogue of Criteria for Assessing the Funding Eligibility
of Open Science Infrastructures. Zenodo, 2025, doi:10.5281/zenodo.15269364.
short: P. Gredler, C. Kaier, P. Danowski, M. Zoyer, K. Rieck, A. Ferus, E. Rosenberger,
A. Löffler, L. Hofer, L. Still, Catalogue of Criteria for Assessing the Funding
Eligibility of Open Science Infrastructures, Zenodo, 2025.
date_created: 2025-08-07T11:10:14Z
date_published: 2025-08-07T00:00:00Z
date_updated: 2025-08-11T07:20:03Z
day: '07'
ddc:
- '020'
department:
- _id: E-Lib
doi: 10.5281/zenodo.15269364
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.5281/zenodo.15269364
month: '08'
oa: 1
oa_version: Published Version
publication_status: published
publisher: Zenodo
status: public
title: Catalogue of criteria for assessing the funding eligibility of Open Science
infrastructures
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: working_paper
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20154'
abstract:
- lang: eng
text: In long-lived mammals, including humans, brain cell homeostasis is critical
for maintaining brain function throughout life. Most neurons are generated during
development and must maintain their cellular identity and plasticity to preserve
brain function. Although extensive studies indicate the importance of recycling
and regenerating cellular molecules to maintain cellular homeostasis, recent evidence
has shown that some proteins and RNAs do not turn over for months and even years.
We propose that these long-lived cellular molecules may be the basis for maintaining
brain function in the long term, but also a potential convergent target of brain
aging. We highlight key discoveries and challenges, and propose potential directions
to unravel the mystery of brain cell longevity.
acknowledgement: The work was supported by the Deutsche Forschungsgemeinschaft (DFG,
German Research Foundation) (470322152 – T1347/3-1; 497658532 – T1347/4-1; 507965872
– T1347/5-1; and 460333672 – CRC1540 Exploring Brain Mechanics) to T.T., the Schram
Foundation (T.T.), the European Research Council (ERC-2018-STG, 804468 EAGER; ERC-2023-COG,
101125034 NEUTIME) to T.T., the Hans-Georg Geis und Xue Hong Dong-Geis Foundation
and Forschungsstiftung Medizin am Universitätsklinikum Erlangen to T.T., and the
Interdisciplinary Centre for Clinical Research Erlangen (Interdisziplinäres Zentrum
für Klinische Forschung, Universitätsklinikum Erlangen; P162 to T.T.). We thank
Dr Laura J. Harrison for editing assistance.
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Martin W
full_name: Hetzer, Martin W
id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
last_name: Hetzer
orcid: 0000-0002-2111-992X
- first_name: Tomohisa
full_name: Toda, Tomohisa
last_name: Toda
citation:
ama: Hetzer M, Toda T. Long-lived cellular molecules in the brain. Trends in
Neurosciences. 2025;48(9):645-654. doi:10.1016/j.tins.2025.07.004
apa: Hetzer, M., & Toda, T. (2025). Long-lived cellular molecules in the brain.
Trends in Neurosciences. Elsevier. https://doi.org/10.1016/j.tins.2025.07.004
chicago: Hetzer, Martin, and Tomohisa Toda. “Long-Lived Cellular Molecules in the
Brain.” Trends in Neurosciences. Elsevier, 2025. https://doi.org/10.1016/j.tins.2025.07.004.
ieee: M. Hetzer and T. Toda, “Long-lived cellular molecules in the brain,” Trends
in Neurosciences, vol. 48, no. 9. Elsevier, pp. 645–654, 2025.
ista: Hetzer M, Toda T. 2025. Long-lived cellular molecules in the brain. Trends
in Neurosciences. 48(9), 645–654.
mla: Hetzer, Martin, and Tomohisa Toda. “Long-Lived Cellular Molecules in the Brain.”
Trends in Neurosciences, vol. 48, no. 9, Elsevier, 2025, pp. 645–54, doi:10.1016/j.tins.2025.07.004.
short: M. Hetzer, T. Toda, Trends in Neurosciences 48 (2025) 645–654.
corr_author: '1'
date_created: 2025-08-10T22:01:29Z
date_published: 2025-09-01T00:00:00Z
date_updated: 2025-12-29T13:47:58Z
day: '01'
ddc:
- '570'
department:
- _id: MaHe
doi: 10.1016/j.tins.2025.07.004
external_id:
isi:
- '001568965400001'
pmid:
- '40744775'
file:
- access_level: open_access
checksum: 90942491b499f70b0bf48b8aec2e7387
content_type: application/pdf
creator: dernst
date_created: 2025-12-29T13:47:27Z
date_updated: 2025-12-29T13:47:27Z
file_id: '20873'
file_name: 2025_TrendsNeurosciences_Hetzer.pdf
file_size: 327847
relation: main_file
success: 1
file_date_updated: 2025-12-29T13:47:27Z
has_accepted_license: '1'
intvolume: ' 48'
isi: 1
issue: '9'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: 645-654
pmid: 1
publication: Trends in Neurosciences
publication_identifier:
eissn:
- 1878-108X
issn:
- 0166-2236
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Long-lived cellular molecules in the brain
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 48
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '20155'
abstract:
- lang: eng
text: We study time averages for the norm of solutions to kinetic Fokker–Planck
equations associated with general Hamiltonians. We provide fully explicit and
constructive decay estimates for systems subject to a confining potential, allowing
fat-tail, subexponential and (super-)exponential local equilibria, which also
include the classic Maxwellian case. The key step in our estimates is a modified
Poincaré inequality, obtained via a Lions–Poincaré inequality and an averaging
lemma.
acknowledgement: The first author was funded by the European Union's Horizon 2020
research andinnovation program under the Marie Sklodowska-Curie grant agreements
754362 and 101034413,and partially by Project EFI (ANR-17-CE40-0030) of the French
National Research Agency (ANR).The work of the second author was partially funded
by the European Research Council (ERC) underthe European Union's Horizon 2020 research
and innovation programme (grant agreement 810367),and by the Agence Nationale de
la Recherche under grants ANR-19-CE40-0010 (QuAMProcs) andANR-21-CE40-0006 (SINEQ).
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Giovanni
full_name: Brigati, Giovanni
id: 63ff57e8-1fbb-11ee-88f2-f558ffc59cf1
last_name: Brigati
- first_name: Gabriel
full_name: Stoltz, Gabriel
last_name: Stoltz
citation:
ama: Brigati G, Stoltz G. How to construct explicit decay rates for kinetic Fokker–Planck
equations? SIAM Journal on Mathematical Analysis. 2025;57(4):3587-3622.
doi:10.1137/24M1700351
apa: Brigati, G., & Stoltz, G. (2025). How to construct explicit decay rates
for kinetic Fokker–Planck equations? SIAM Journal on Mathematical Analysis.
Society for Industrial and Applied Mathematics. https://doi.org/10.1137/24M1700351
chicago: Brigati, Giovanni, and Gabriel Stoltz. “How to Construct Explicit Decay
Rates for Kinetic Fokker–Planck Equations?” SIAM Journal on Mathematical Analysis.
Society for Industrial and Applied Mathematics, 2025. https://doi.org/10.1137/24M1700351.
ieee: G. Brigati and G. Stoltz, “How to construct explicit decay rates for kinetic
Fokker–Planck equations?,” SIAM Journal on Mathematical Analysis, vol.
57, no. 4. Society for Industrial and Applied Mathematics, pp. 3587–3622, 2025.
ista: Brigati G, Stoltz G. 2025. How to construct explicit decay rates for kinetic
Fokker–Planck equations? SIAM Journal on Mathematical Analysis. 57(4), 3587–3622.
mla: Brigati, Giovanni, and Gabriel Stoltz. “How to Construct Explicit Decay Rates
for Kinetic Fokker–Planck Equations?” SIAM Journal on Mathematical Analysis,
vol. 57, no. 4, Society for Industrial and Applied Mathematics, 2025, pp. 3587–622,
doi:10.1137/24M1700351.
short: G. Brigati, G. Stoltz, SIAM Journal on Mathematical Analysis 57 (2025) 3587–3622.
corr_author: '1'
date_created: 2025-08-10T22:01:29Z
date_published: 2025-08-01T00:00:00Z
date_updated: 2025-11-05T13:51:40Z
day: '01'
department:
- _id: JaMa
doi: 10.1137/24M1700351
ec_funded: 1
external_id:
arxiv:
- '2302.14506'
isi:
- '001550830900006'
intvolume: ' 57'
isi: 1
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2302.14506
month: '08'
oa: 1
oa_version: Preprint
page: 3587-3622
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
call_identifier: H2020
grant_number: '101034413'
name: 'IST-BRIDGE: International postdoctoral program'
publication: SIAM Journal on Mathematical Analysis
publication_identifier:
eissn:
- 1095-7154
issn:
- 0036-1410
publication_status: published
publisher: Society for Industrial and Applied Mathematics
quality_controlled: '1'
scopus_import: '1'
status: public
title: How to construct explicit decay rates for kinetic Fokker–Planck equations?
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 57
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20182'
abstract:
- lang: eng
text: Sex chromosomes have evolved many times throughout the tree of life, and understanding
what has shaped their unusual morphological, sequence, and regulatory features
has been a long-standing goal. Most early insights into insect sex chromosome
biology came from a few model species, such as the fruit fly Drosophila melanogaster,
which limited broad-scale evolutionary inferences. More recently, extensive comparative
genomics studies have uncovered several unexpected patterns, which we highlight
in this review. First, we describe the conservation of the ancestral X chromosome
over 450 million years but also its recurrent turnover (i.e. its reversal to an
autosome when a new X chromosome arose) in at least one order. We then summarize
classical and more recent findings on how insects modulate the expression of X-linked
genes following the degradation of the Y chromosome and how the diverse mechanisms
of dosage compensation identified may elucidate important principles of sex chromosome
regulatory evolution.
acknowledgement: This work was supported by an Austrian Research Fund (FWF) grant
to B.V. (PAT 8748323) and by the Louisiana Board of Regents Research Competitiveness
Subprogram (LEQSF(2025-28)-RD-A-20) to MAT.
article_number: '101411'
article_processing_charge: Yes (via OA deal)
article_type: review
author:
- first_name: Melissa A
full_name: Toups, Melissa A
id: 4E099E4E-F248-11E8-B48F-1D18A9856A87
last_name: Toups
orcid: 0000-0002-9752-7380
- first_name: Beatriz
full_name: Vicoso, Beatriz
id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
last_name: Vicoso
orcid: 0000-0002-4579-8306
citation:
ama: 'Toups MA, Vicoso B. Insect sex chromosome evolution: Conservation, turnover,
and mechanisms of dosage compensation. Current Opinion in Insect Science.
2025;72. doi:10.1016/j.cois.2025.101411'
apa: 'Toups, M. A., & Vicoso, B. (2025). Insect sex chromosome evolution: Conservation,
turnover, and mechanisms of dosage compensation. Current Opinion in Insect
Science. Elsevier. https://doi.org/10.1016/j.cois.2025.101411'
chicago: 'Toups, Melissa A, and Beatriz Vicoso. “Insect Sex Chromosome Evolution:
Conservation, Turnover, and Mechanisms of Dosage Compensation.” Current Opinion
in Insect Science. Elsevier, 2025. https://doi.org/10.1016/j.cois.2025.101411.'
ieee: 'M. A. Toups and B. Vicoso, “Insect sex chromosome evolution: Conservation,
turnover, and mechanisms of dosage compensation,” Current Opinion in Insect
Science, vol. 72. Elsevier, 2025.'
ista: 'Toups MA, Vicoso B. 2025. Insect sex chromosome evolution: Conservation,
turnover, and mechanisms of dosage compensation. Current Opinion in Insect Science.
72, 101411.'
mla: 'Toups, Melissa A., and Beatriz Vicoso. “Insect Sex Chromosome Evolution: Conservation,
Turnover, and Mechanisms of Dosage Compensation.” Current Opinion in Insect
Science, vol. 72, 101411, Elsevier, 2025, doi:10.1016/j.cois.2025.101411.'
short: M.A. Toups, B. Vicoso, Current Opinion in Insect Science 72 (2025).
corr_author: '1'
date_created: 2025-08-17T22:01:35Z
date_published: 2025-12-01T00:00:00Z
date_updated: 2025-12-30T13:14:38Z
day: '01'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1016/j.cois.2025.101411
external_id:
isi:
- '001582424100001'
file:
- access_level: open_access
checksum: 262640abc34277686b56eb60102976f6
content_type: application/pdf
creator: dernst
date_created: 2025-12-30T13:14:20Z
date_updated: 2025-12-30T13:14:20Z
file_id: '20917'
file_name: 2025_CurrOpinionInsectScience_Toups.pdf
file_size: 897079
relation: main_file
success: 1
file_date_updated: 2025-12-30T13:14:20Z
has_accepted_license: '1'
intvolume: ' 72'
isi: 1
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
project:
- _id: 8ed82125-16d5-11f0-9cad-fbcae312235b
grant_number: PAT 8748323
name: Sex chromosomes in evolution and development
publication: Current Opinion in Insect Science
publication_identifier:
eissn:
- 2214-5753
issn:
- 2214-5745
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Insect sex chromosome evolution: Conservation, turnover, and mechanisms of
dosage compensation'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 72
year: '2025'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '20183'
abstract:
- lang: eng
text: The unequal segregation of organelles has been proposed to be an intrinsic
mechanism that contributes to cell fate divergence during asymmetric cell division;
however, in vivo evidence is sparse. Using super-resolution microscopy, we analysed
the segregation of organelles during the division of the neuroblast QL.p in C.
elegans larvae. QL.p divides to generate a daughter that survives, QL.pa, and
a daughter that dies, QL.pp. We found that mitochondria segregate unequally by
density and morphology and that this is dependent on mitochondrial dynamics. Furthermore,
we found that mitochondrial density in QL.pp correlates with the time it takes
QL.pp to die. We propose that low mitochondrial density in QL.pp promotes the
cell death fate and ensures that QL.pp dies in a highly reproducible and timely
manner. Our results provide in vivo evidence that the unequal segregation of mitochondria
can contribute to cell fate divergence during asymmetric cell division in a developing
animal.
acknowledgement: We thank members of the Conradt lab, the Center for Cell and Molecular
Dynamics (https://www.uclccmd.co.uk/) and T. Schedl for discussions and comments
on the manuscript. We thank L. McGuinness for excellent technical support. Some
strains were provided by the Caenorhabditis Genetics Center (CGC), which is funded
by NIH Office of Research Infrastructure Programs (P40 OD010440). We thank Alex
Hajnal (University of Zurich, Switzerland) and Andrew deMello (ETH Zurich, Switzerland)
for their support of S.B. This work was supported by a predoctoral fellowship from
the Studienstiftung des deutschen Volkes to NM, funds from UCL (Division of Biosciences,
UCL LSM Capital Equipment Fund) to B.C., and a Wolfson Fellowship from the Royal
Society (https://royalsociety.org/) to B.C. (RSWF\R1\180008), and the Biotechnology
and Biological Sciences Research Council (https://bbsrc.ukri.org/) (BB/V007572/1
and BB/V015648/1to B.C.).
article_number: '7174'
article_processing_charge: Yes
article_type: original
author:
- first_name: Ioannis
full_name: Segos, Ioannis
last_name: Segos
- first_name: Jens
full_name: Van Eeckhoven, Jens
last_name: Van Eeckhoven
- first_name: Simon
full_name: Berger, Simon
last_name: Berger
- first_name: Nikhil
full_name: Mishra, Nikhil
id: C4D70E82-1081-11EA-B3ED-9A4C3DDC885E
last_name: Mishra
orcid: 0000-0002-6425-5788
- first_name: Eric J.
full_name: Lambie, Eric J.
last_name: Lambie
- first_name: Barbara
full_name: Conradt, Barbara
last_name: Conradt
citation:
ama: Segos I, Van Eeckhoven J, Berger S, Mishra N, Lambie EJ, Conradt B. Unequal
segregation of mitochondria during asymmetric cell division contributes to cell
fate divergence in sister cells in vivo. Nature Communications. 2025;16.
doi:10.1038/s41467-025-62484-5
apa: Segos, I., Van Eeckhoven, J., Berger, S., Mishra, N., Lambie, E. J., &
Conradt, B. (2025). Unequal segregation of mitochondria during asymmetric cell
division contributes to cell fate divergence in sister cells in vivo. Nature
Communications. Springer Nature. https://doi.org/10.1038/s41467-025-62484-5
chicago: Segos, Ioannis, Jens Van Eeckhoven, Simon Berger, Nikhil Mishra, Eric J.
Lambie, and Barbara Conradt. “Unequal Segregation of Mitochondria during Asymmetric
Cell Division Contributes to Cell Fate Divergence in Sister Cells in Vivo.” Nature
Communications. Springer Nature, 2025. https://doi.org/10.1038/s41467-025-62484-5.
ieee: I. Segos, J. Van Eeckhoven, S. Berger, N. Mishra, E. J. Lambie, and B. Conradt,
“Unequal segregation of mitochondria during asymmetric cell division contributes
to cell fate divergence in sister cells in vivo,” Nature Communications,
vol. 16. Springer Nature, 2025.
ista: Segos I, Van Eeckhoven J, Berger S, Mishra N, Lambie EJ, Conradt B. 2025.
Unequal segregation of mitochondria during asymmetric cell division contributes
to cell fate divergence in sister cells in vivo. Nature Communications. 16, 7174.
mla: Segos, Ioannis, et al. “Unequal Segregation of Mitochondria during Asymmetric
Cell Division Contributes to Cell Fate Divergence in Sister Cells in Vivo.” Nature
Communications, vol. 16, 7174, Springer Nature, 2025, doi:10.1038/s41467-025-62484-5.
short: I. Segos, J. Van Eeckhoven, S. Berger, N. Mishra, E.J. Lambie, B. Conradt,
Nature Communications 16 (2025).
date_created: 2025-08-17T22:01:35Z
date_published: 2025-08-04T00:00:00Z
date_updated: 2025-09-01T09:47:29Z
day: '04'
ddc:
- '570'
department:
- _id: CaHe
doi: 10.1038/s41467-025-62484-5
external_id:
pmid:
- '40759648'
file:
- access_level: open_access
checksum: f28e73963ea1f55876d0d1afca0f706a
content_type: application/pdf
creator: dernst
date_created: 2025-09-01T09:46:44Z
date_updated: 2025-09-01T09:46:44Z
file_id: '20261'
file_name: 2025_NatureComm_Segos.pdf
file_size: 3775190
relation: main_file
success: 1
file_date_updated: 2025-09-01T09:46:44Z
has_accepted_license: '1'
intvolume: ' 16'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Communications
publication_identifier:
eissn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Unequal segregation of mitochondria during asymmetric cell division contributes
to cell fate divergence in sister cells in vivo
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 16
year: '2025'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '20184'
abstract:
- lang: eng
text: Specialized DNA polymerases facilitate various cellular processes. Despite
extensive research, the mutagenic effects of these error-prone enzymes on genomes
are not fully understood. Here we show that Pol IV promotes genomic instability
in Pseudomonas aeruginosa by misincorporating oxidized guanine nucleotides. This
activity led to a distinctive mutational signature, characterized by A-to-C transversions
occurring preferentially at AT sites flanked by a 5’G and/or 3’C. Furthermore,
Pol IV preferentially targeted pathogenicity genes located at specific chromosomal
locations near the replication termination region and rRNA-encoding operons. Half
of the mutation events catalyzed by Pol IV impaired gene function. This can be
attributed to the bias of Pol IV for mutating codons with its preferred sequence
contexts, leading to substitutions to unreactive alanine and glycine residues.
Remarkably, mutation signatures identified for Pol IV were found in clinical isolate
genomes of P. aeruginosa, providing compelling evidence for its role in genetic
diversification during pathogen adaptation.
acknowledgement: "This work was supported by the Secretaría de Ciencia y Técnica (33620230100926CB),
Universidad Nacional de Córdoba; and the Agencia Nacional de Promoción Científica
y Técnica (PICT 2018-4527).\r\n\r\n"
article_number: '1148'
article_processing_charge: Yes
article_type: original
author:
- first_name: Sofía D.
full_name: Castell, Sofía D.
last_name: Castell
- first_name: Consuelo M.
full_name: Fernandez, Consuelo M.
last_name: Fernandez
- first_name: Ignacio N.
full_name: Tumas, Ignacio N.
last_name: Tumas
- first_name: Lucía M.
full_name: Margara, Lucía M.
last_name: Margara
- first_name: Maria C
full_name: Miserendino, Maria C
id: 273e0cbd-72f0-11ef-b75a-f9f932e292fa
last_name: Miserendino
- first_name: Danilo G.
full_name: Ceschin, Danilo G.
last_name: Ceschin
- first_name: Roberto J.
full_name: Pezza, Roberto J.
last_name: Pezza
- first_name: Mariela R.
full_name: Monti, Mariela R.
last_name: Monti
citation:
ama: Castell SD, Fernandez CM, Tumas IN, et al. The low-fidelity DNA Pol IV accelerates
evolution of pathogenicity genes in Pseudomonas aeruginosa. Communications
Biology. 2025;8. doi:10.1038/s42003-025-08589-5
apa: Castell, S. D., Fernandez, C. M., Tumas, I. N., Margara, L. M., Miserendino,
M. C., Ceschin, D. G., … Monti, M. R. (2025). The low-fidelity DNA Pol IV accelerates
evolution of pathogenicity genes in Pseudomonas aeruginosa. Communications
Biology. Springer Nature. https://doi.org/10.1038/s42003-025-08589-5
chicago: Castell, Sofía D., Consuelo M. Fernandez, Ignacio N. Tumas, Lucía M. Margara,
Maria C Miserendino, Danilo G. Ceschin, Roberto J. Pezza, and Mariela R. Monti.
“The Low-Fidelity DNA Pol IV Accelerates Evolution of Pathogenicity Genes in Pseudomonas
Aeruginosa.” Communications Biology. Springer Nature, 2025. https://doi.org/10.1038/s42003-025-08589-5.
ieee: S. D. Castell et al., “The low-fidelity DNA Pol IV accelerates evolution
of pathogenicity genes in Pseudomonas aeruginosa,” Communications Biology,
vol. 8. Springer Nature, 2025.
ista: Castell SD, Fernandez CM, Tumas IN, Margara LM, Miserendino MC, Ceschin DG,
Pezza RJ, Monti MR. 2025. The low-fidelity DNA Pol IV accelerates evolution of
pathogenicity genes in Pseudomonas aeruginosa. Communications Biology. 8, 1148.
mla: Castell, Sofía D., et al. “The Low-Fidelity DNA Pol IV Accelerates Evolution
of Pathogenicity Genes in Pseudomonas Aeruginosa.” Communications Biology,
vol. 8, 1148, Springer Nature, 2025, doi:10.1038/s42003-025-08589-5.
short: S.D. Castell, C.M. Fernandez, I.N. Tumas, L.M. Margara, M.C. Miserendino,
D.G. Ceschin, R.J. Pezza, M.R. Monti, Communications Biology 8 (2025).
date_created: 2025-08-17T22:01:35Z
date_published: 2025-08-02T00:00:00Z
date_updated: 2025-09-30T14:18:46Z
day: '02'
ddc:
- '570'
department:
- _id: PaSc
- _id: GradSch
doi: 10.1038/s42003-025-08589-5
external_id:
isi:
- '001541878500001'
pmid:
- '40753298'
has_accepted_license: '1'
intvolume: ' 8'
isi: 1
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
main_file_link:
- open_access: '1'
url: https://doi.org/10.1038/s42003-025-08589-5
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
publication: Communications Biology
publication_identifier:
eissn:
- 2399-3642
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: The low-fidelity DNA Pol IV accelerates evolution of pathogenicity genes in
Pseudomonas aeruginosa
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 8
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20185'
abstract:
- lang: eng
text: We show a local rigidity result for the integrability of symplectic billiards.
We prove that any domain which is close to an ellipse, and for which the symplectic
billiard map is rationally integrable must be an ellipse as well. This is in spirit
of the result of [2] for Birkhoff billiards.
acknowledgement: The author would like to thank Corentin Fierobe, Vadim Kaloshin,
Illya Koval and Yunzhe Li for useful discussions. The author would also like to
thank the referee for useful remarks. Open access funding provided by Institute
of Science and Technology (IST Austria). European Research Council (885707) Mr Daniel
Tsodikovich
article_number: '306'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Daniel
full_name: Tsodikovich, Daniel
id: 04531810-fb3e-11ef-87f0-800a4ce333db
last_name: Tsodikovich
citation:
ama: Tsodikovich D. Local rigidity for symplectic billiards. Journal of Geometric
Analysis. 2025;35(10). doi:10.1007/s12220-025-02148-4
apa: Tsodikovich, D. (2025). Local rigidity for symplectic billiards. Journal
of Geometric Analysis. Springer Nature. https://doi.org/10.1007/s12220-025-02148-4
chicago: Tsodikovich, Daniel. “Local Rigidity for Symplectic Billiards.” Journal
of Geometric Analysis. Springer Nature, 2025. https://doi.org/10.1007/s12220-025-02148-4.
ieee: D. Tsodikovich, “Local rigidity for symplectic billiards,” Journal of Geometric
Analysis, vol. 35, no. 10. Springer Nature, 2025.
ista: Tsodikovich D. 2025. Local rigidity for symplectic billiards. Journal of Geometric
Analysis. 35(10), 306.
mla: Tsodikovich, Daniel. “Local Rigidity for Symplectic Billiards.” Journal
of Geometric Analysis, vol. 35, no. 10, 306, Springer Nature, 2025, doi:10.1007/s12220-025-02148-4.
short: D. Tsodikovich, Journal of Geometric Analysis 35 (2025).
corr_author: '1'
date_created: 2025-08-17T22:01:35Z
date_published: 2025-08-07T00:00:00Z
date_updated: 2025-12-30T09:29:27Z
day: '07'
ddc:
- '510'
department:
- _id: VaKa
doi: 10.1007/s12220-025-02148-4
ec_funded: 1
external_id:
arxiv:
- '2501.08849'
isi:
- '001546433200002'
file:
- access_level: open_access
checksum: ed86500742b3fd93db3287558a630383
content_type: application/pdf
creator: dernst
date_created: 2025-12-30T09:28:58Z
date_updated: 2025-12-30T09:28:58Z
file_id: '20907'
file_name: 2025_JourGeomAnalysis_Tsodikovich.pdf
file_size: 484344
relation: main_file
success: 1
file_date_updated: 2025-12-30T09:28:58Z
has_accepted_license: '1'
intvolume: ' 35'
isi: 1
issue: '10'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
project:
- _id: 9B8B92DE-BA93-11EA-9121-9846C619BF3A
call_identifier: H2020
grant_number: '885707'
name: Spectral rigidity and integrability for billiards and geodesic flows
publication: Journal of Geometric Analysis
publication_identifier:
issn:
- 1050-6926
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Local rigidity for symplectic billiards
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 35
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20186'
abstract:
- lang: eng
text: Enforcement of information-flow policies has been extensively studied by language-based
approaches over the past few decades. In this paper, we propose an alternative,
novel, general, and effective approach using enforcement of hyperproperties– a
powerful formalism for expressing and reasoning about a wide range of information-flow
security policies. We study black- vs. gray- vs. white-box enforcement of hyperproperties
expressed by nondeterministic finite-word hyperautomata (NFH), where the enforcer
has null, some, or complete information about the implementation of the system
under scrutiny. Given an NFH, in order to generate a runtime enforcer, we reduce
the problem to controller synthesis for hyperproperties and subsequently to the
satisfiability problem for quantified Boolean formulas (QBFs). The resulting enforcers
are transferable with low-overhead. We conduct a rich set of case studies, including
information-flow control for JavaScript code, as well as synthesizing obfuscators
for control plants.
acknowledgement: This project was funded in part by the Austrian Science Fund (FWF)
SFB project SpyCoDe F8502, Vienna Science and Technology Fund (WWTF) [10.47379/ICT19018]
(ProbInG) and WWTF project ICT22-023 (TAIGER), National Science Foundation (NSF)
CPS Award 1837680, NSF award ECCS-2144416 and NSF SaTC Award 2245114. Open access
funding provided by Institute of Science and Technology (IST Austria).
article_number: '30'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Tzu Han
full_name: Hsu, Tzu Han
last_name: Hsu
- first_name: Ana A
full_name: Oliveira Da Costa, Ana A
id: 8b282559-50b0-11ef-861e-d6ace0d92e9b
last_name: Oliveira Da Costa
- first_name: Andrew
full_name: Wintenberg, Andrew
last_name: Wintenberg
- first_name: Ezio
full_name: Bartocci, Ezio
last_name: Bartocci
- first_name: Borzoo
full_name: Bonakdarpour, Borzoo
last_name: Bonakdarpour
citation:
ama: Hsu TH, Oliveira da Costa AA, Wintenberg A, Bartocci E, Bonakdarpour B. Gray-box
runtime enforcement of hyperproperties. Acta Informatica. 2025;62(3). doi:10.1007/s00236-025-00502-1
apa: Hsu, T. H., Oliveira da Costa, A. A., Wintenberg, A., Bartocci, E., & Bonakdarpour,
B. (2025). Gray-box runtime enforcement of hyperproperties. Acta Informatica.
Springer Nature. https://doi.org/10.1007/s00236-025-00502-1
chicago: Hsu, Tzu Han, Ana A Oliveira da Costa, Andrew Wintenberg, Ezio Bartocci,
and Borzoo Bonakdarpour. “Gray-Box Runtime Enforcement of Hyperproperties.” Acta
Informatica. Springer Nature, 2025. https://doi.org/10.1007/s00236-025-00502-1.
ieee: T. H. Hsu, A. A. Oliveira da Costa, A. Wintenberg, E. Bartocci, and B. Bonakdarpour,
“Gray-box runtime enforcement of hyperproperties,” Acta Informatica, vol.
62, no. 3. Springer Nature, 2025.
ista: Hsu TH, Oliveira da Costa AA, Wintenberg A, Bartocci E, Bonakdarpour B. 2025.
Gray-box runtime enforcement of hyperproperties. Acta Informatica. 62(3), 30.
mla: Hsu, Tzu Han, et al. “Gray-Box Runtime Enforcement of Hyperproperties.” Acta
Informatica, vol. 62, no. 3, 30, Springer Nature, 2025, doi:10.1007/s00236-025-00502-1.
short: T.H. Hsu, A.A. Oliveira da Costa, A. Wintenberg, E. Bartocci, B. Bonakdarpour,
Acta Informatica 62 (2025).
corr_author: '1'
date_created: 2025-08-17T22:01:36Z
date_published: 2025-09-01T00:00:00Z
date_updated: 2025-09-30T14:20:11Z
day: '01'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.1007/s00236-025-00502-1
external_id:
isi:
- '001546115300001'
file:
- access_level: open_access
checksum: 90a43350fd4a8c5cb5b1b0e1aea7970d
content_type: application/pdf
creator: dernst
date_created: 2025-09-02T05:53:47Z
date_updated: 2025-09-02T05:53:47Z
file_id: '20267'
file_name: 2025_ActaInformatica_Hsu.pdf
file_size: 6505049
relation: main_file
success: 1
file_date_updated: 2025-09-02T05:53:47Z
has_accepted_license: '1'
intvolume: ' 62'
isi: 1
issue: '3'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
project:
- _id: 34a1b658-11ca-11ed-8bc3-c75229f0241e
grant_number: F8502
name: Interface Theory for Security and Privacy
publication: Acta Informatica
publication_identifier:
eissn:
- 1432-0525
issn:
- 0001-5903
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Gray-box runtime enforcement of hyperproperties
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 62
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20188'
abstract:
- lang: eng
text: Collective cell migration is coordinated by the front-to-rear intercellular
propagation of EGFR-Ras-ERK pathway activation. However, the molecular mechanisms
integrating front-to-rear information into this intercellular signaling cascade,
particularly the determinants of cellular front-side specification, remain elusive.
We visualized the activity of EGFR, Ras, Rac1 and Rab5A (hereafter Rab5) by using
FRET biosensors and chemogenetic tools. Whereas EGFR activation was uniformly
observed within cells, Ras activation was biased to the front side within cells.
The polarized Ras activation depended on Merlin and Rac1, which also showed front-biased
activation. Furthermore, Rab5, a crucial regulator of cell migration, demonstrated
similar front-biased activation and was found to function downstream of Ras while
being necessary for Rac1 activation. Thus, the positive feedback loop consisting
of Ras, Rab5 and Rac1 is activated primarily at the front of collectively migrating
cells. These findings offer new spatio-temporal insight into processing front–rear
information during collective cell migration.
acknowledgement: We are grateful to the members of the Matsuda Laboratory for their
helpful input, to K. Hirano, T. Uesugi and K. Takakura, who provided technical assistance,
and to the Medical Research Support Center of Kyoto University for DNA sequence
analysis. This work was supported by the Kyoto University Live Imaging Center. Financial
support was provided by Japan Society for the Promotion of Science (JSPS) KAKENHI
grants (21H05226 to K.T., 19H00993 and 20H05898 to M.M.), a Japan Science and Technology
Agency (JST) CREST grant (JPMJCR1654 to M.M.), and a JST Moonshot Research and Development
Program grant (JPMJPS2022 to M.M.). Open Access funding provided by Tokushima University.
Deposited in PMC for immediate release.
article_number: '263779'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Yuya
full_name: Jikko, Yuya
last_name: Jikko
- first_name: Eriko
full_name: Deguchi, Eriko
last_name: Deguchi
- first_name: Kimiya
full_name: Matsuda, Kimiya
last_name: Matsuda
- first_name: Naoya
full_name: Hino, Naoya
id: 5299a9ce-7679-11eb-a7bc-d1e62b936307
last_name: Hino
- first_name: Shinya
full_name: Tsukiji, Shinya
last_name: Tsukiji
- first_name: Michiyuki
full_name: Matsuda, Michiyuki
last_name: Matsuda
- first_name: Kenta
full_name: Terai, Kenta
last_name: Terai
citation:
ama: Jikko Y, Deguchi E, Matsuda K, et al. Front-biased activation of the Ras-Rab5-Rac1
loop coordinates collective cell migration. Journal of Cell Science. 2025;138(15).
doi:10.1242/jcs.263779
apa: Jikko, Y., Deguchi, E., Matsuda, K., Hino, N., Tsukiji, S., Matsuda, M., &
Terai, K. (2025). Front-biased activation of the Ras-Rab5-Rac1 loop coordinates
collective cell migration. Journal of Cell Science. The Company of Biologists.
https://doi.org/10.1242/jcs.263779
chicago: Jikko, Yuya, Eriko Deguchi, Kimiya Matsuda, Naoya Hino, Shinya Tsukiji,
Michiyuki Matsuda, and Kenta Terai. “Front-Biased Activation of the Ras-Rab5-Rac1
Loop Coordinates Collective Cell Migration.” Journal of Cell Science. The
Company of Biologists, 2025. https://doi.org/10.1242/jcs.263779.
ieee: Y. Jikko et al., “Front-biased activation of the Ras-Rab5-Rac1 loop
coordinates collective cell migration,” Journal of Cell Science, vol. 138,
no. 15. The Company of Biologists, 2025.
ista: Jikko Y, Deguchi E, Matsuda K, Hino N, Tsukiji S, Matsuda M, Terai K. 2025.
Front-biased activation of the Ras-Rab5-Rac1 loop coordinates collective cell
migration. Journal of Cell Science. 138(15), 263779.
mla: Jikko, Yuya, et al. “Front-Biased Activation of the Ras-Rab5-Rac1 Loop Coordinates
Collective Cell Migration.” Journal of Cell Science, vol. 138, no. 15,
263779, The Company of Biologists, 2025, doi:10.1242/jcs.263779.
short: Y. Jikko, E. Deguchi, K. Matsuda, N. Hino, S. Tsukiji, M. Matsuda, K. Terai,
Journal of Cell Science 138 (2025).
date_created: 2025-08-17T22:01:36Z
date_published: 2025-08-01T00:00:00Z
date_updated: 2025-11-27T14:12:24Z
day: '01'
ddc:
- '570'
department:
- _id: CaHe
doi: 10.1242/jcs.263779
external_id:
isi:
- '001567723900009'
pmid:
- '40667649'
file:
- access_level: open_access
checksum: 29f42619dab5ce251a20c769ed4581c0
content_type: application/pdf
creator: dernst
date_created: 2025-09-01T10:02:24Z
date_updated: 2025-09-01T10:02:24Z
file_id: '20262'
file_name: 2025_JourCellScience_Jikko.pdf
file_size: 12393297
relation: main_file
success: 1
file_date_updated: 2025-09-01T10:02:24Z
has_accepted_license: '1'
intvolume: ' 138'
isi: 1
issue: '15'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
publication: Journal of Cell Science
publication_identifier:
eissn:
- 1477-9137
issn:
- ' 0021-9533'
publication_status: published
publisher: The Company of Biologists
quality_controlled: '1'
scopus_import: '1'
status: public
title: Front-biased activation of the Ras-Rab5-Rac1 loop coordinates collective cell
migration
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 138
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
_id: '20189'
abstract:
- lang: eng
text: Certification was made mandatory for the first time in the latest hardware
model checking competition. In this case study, we investigate the trade-offs
of requiring certificates for both passing and failing properties in the competition.
Our evaluation shows that participating model checkers were able to produce compact,
correct certificates that could be verified with minimal overhead. Furthermore,
the certifying winner of the competition outperforms the previous non-certifying
state-of-the-art model checker, demonstrating that certification can be adopted
without compromising model checking efficiency.
acknowledgement: "This work is supported in part by the ERC-2020-AdG 101020093, the
LIT AI Lab funded by the State of Upper Austria, the Research Council of Finland
under the project 336092, and a gift from Intel Corporation.\r\nFurthermore we of
course also owe a big thank-you to the submitters of model checkers and benchmarks
to the competition over all these years. Without their enthusiasm and support neither
the competition nor this study would exist."
alternative_title:
- LNCS
article_processing_charge: Yes (in subscription journal)
author:
- first_name: Nils
full_name: Froleyks, Nils
last_name: Froleyks
- first_name: Zhengqi
full_name: Yu, Zhengqi
id: 20aa2ae8-f2f1-11ed-bbfa-8205053f1342
last_name: Yu
orcid: 0000-0002-4993-773X
- first_name: Mathias
full_name: Preiner, Mathias
last_name: Preiner
- first_name: Armin
full_name: Biere, Armin
last_name: Biere
- first_name: Keijo
full_name: Heljanko, Keijo
last_name: Heljanko
citation:
ama: 'Froleyks N, Yu E, Preiner M, Biere A, Heljanko K. Introducing certificates
to the hardware model checking competition. In: 37th International Conference
on Computer Aided Verification. Vol 15931. Springer Nature; 2025:281-295.
doi:10.1007/978-3-031-98668-0_14'
apa: 'Froleyks, N., Yu, E., Preiner, M., Biere, A., & Heljanko, K. (2025). Introducing
certificates to the hardware model checking competition. In 37th International
Conference on Computer Aided Verification (Vol. 15931, pp. 281–295). Zagreb,
Croatia: Springer Nature. https://doi.org/10.1007/978-3-031-98668-0_14'
chicago: Froleyks, Nils, Emily Yu, Mathias Preiner, Armin Biere, and Keijo Heljanko.
“Introducing Certificates to the Hardware Model Checking Competition.” In 37th
International Conference on Computer Aided Verification, 15931:281–95. Springer
Nature, 2025. https://doi.org/10.1007/978-3-031-98668-0_14.
ieee: N. Froleyks, E. Yu, M. Preiner, A. Biere, and K. Heljanko, “Introducing certificates
to the hardware model checking competition,” in 37th International Conference
on Computer Aided Verification, Zagreb, Croatia, 2025, vol. 15931, pp. 281–295.
ista: 'Froleyks N, Yu E, Preiner M, Biere A, Heljanko K. 2025. Introducing certificates
to the hardware model checking competition. 37th International Conference on Computer
Aided Verification. CAV: Computer Aided Verification, LNCS, vol. 15931, 281–295.'
mla: Froleyks, Nils, et al. “Introducing Certificates to the Hardware Model Checking
Competition.” 37th International Conference on Computer Aided Verification,
vol. 15931, Springer Nature, 2025, pp. 281–95, doi:10.1007/978-3-031-98668-0_14.
short: N. Froleyks, E. Yu, M. Preiner, A. Biere, K. Heljanko, in:, 37th International
Conference on Computer Aided Verification, Springer Nature, 2025, pp. 281–295.
conference:
end_date: 2025-07-25
location: Zagreb, Croatia
name: 'CAV: Computer Aided Verification'
start_date: 2025-07-23
date_created: 2025-08-17T22:01:36Z
date_published: 2025-01-01T00:00:00Z
date_updated: 2025-12-01T12:34:05Z
day: '01'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.1007/978-3-031-98668-0_14
ec_funded: 1
external_id:
isi:
- '001562507100014'
file:
- access_level: open_access
checksum: 15ec1bc9b9409d3b2736f4c9d5f42fd1
content_type: application/pdf
creator: dernst
date_created: 2025-09-02T05:46:10Z
date_updated: 2025-09-02T05:46:10Z
file_id: '20266'
file_name: 2025_CAV_Froleyks.pdf
file_size: 1078274
relation: main_file
success: 1
file_date_updated: 2025-09-02T05:46:10Z
has_accepted_license: '1'
intvolume: ' 15931'
isi: 1
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 281-295
project:
- _id: 62781420-2b32-11ec-9570-8d9b63373d4d
call_identifier: H2020
grant_number: '101020093'
name: Vigilant Algorithmic Monitoring of Software
publication: 37th International Conference on Computer Aided Verification
publication_identifier:
eissn:
- 1611-3349
isbn:
- '9783031986673'
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Introducing certificates to the hardware model checking competition
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 15931
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
_id: '20191'
abstract:
- lang: eng
text: High-entropy alloys (HEAs) show great potential for catalyzing complex multi-step
reactions, but optimizing their parameters, i.e., composition, but also their
crystallinity and morphology, remains a significant challenge. In this study,
FeCoNiMoW HEAs are synthesized into either amorphous nanosheets (HEANS) or crystalline
nanoparticles (HEANP), which are then used to catalyze the lithium–sulfur (Li–S)
reaction of Li–S batteries (LSBs). Evaluations in symmetric cells, coin cells,
and pouch cells reveal that HEANS significantly enhance LSB performance, achieving
initial discharge capacities up to 1632 mAh g−1. The batteries also exhibit excellent
cycling stability over 1000 cycles at 3Cand maintain high-rate performance up
to 10C with a capacity of 614 mAh g−1. Comprehensive in situ analyses and density
functional theory calculations demonstrate that amorphous HEANS provide more active
sites, better ionic conductivity and stronger chemical interactions with lithium
polysulfides (LiPS). These properties effectively suppress the shuttle effect,
promote the complete S8 → Li2S conversion by reducing the impedance of the solid-electrolyte
interphase, and accelerate the Li2S4 → Li2S2 step by lowering the nucleation energy
barrier. Overall, this study highlights the superior catalytic properties of amorphous
2D HEAs in LSBs and offers new insights into the mechanisms of LiPS conversion.
acknowledged_ssus:
- _id: EM-Fac
acknowledgement: The authors acknowledge support from the 2BoSS project of the ERA-MIN3
program with the Spanish grant number PCI2022-132985/AEI/10.13039/50110001103, and
funding from Generalitat de Catalunya 2021SGR01581 and European Union NextGenerationEU/PRTR.
L.Yang, C.Huang, X.Lu, A.Yu, C.Li, J.Yu, and X.Bi thank the China Scholarship Council
(CSC) for the scholarship support. This research was supported by the Scientific
Service Units (SSU) of ISTA through resources provided by the Electron Microscopy
Facility (EMF), and by the Werner Siemens Foundation (WSS) for financial support.
article_number: e13859
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Ren
full_name: He, Ren
last_name: He
- first_name: Seungho
full_name: Lee, Seungho
id: BB243B88-D767-11E9-B658-BC13E6697425
last_name: Lee
orcid: 0000-0002-6962-8598
- first_name: Yang
full_name: Ding, Yang
last_name: Ding
- first_name: Chen
full_name: Huang, Chen
last_name: Huang
- first_name: Xuan
full_name: Lu, Xuan
last_name: Lu
- first_name: Lirong
full_name: Zheng, Lirong
last_name: Zheng
- first_name: Ao
full_name: Yu, Ao
last_name: Yu
- first_name: Chaoyue
full_name: Zhang, Chaoyue
last_name: Zhang
- first_name: Canhuang
full_name: Li, Canhuang
last_name: Li
- first_name: Xiaoyu
full_name: Bi, Xiaoyu
last_name: Bi
- first_name: Yaqiang
full_name: Li, Yaqiang
last_name: Li
- first_name: Yaqi
full_name: Liao, Yaqi
last_name: Liao
- first_name: Junshan
full_name: Li, Junshan
last_name: Li
- first_name: Ahmad
full_name: Ostovari Moghaddam, Ahmad
last_name: Ostovari Moghaddam
- first_name: Salimov
full_name: Yernar, Salimov
last_name: Yernar
- first_name: Ying
full_name: Xu, Ying
last_name: Xu
- first_name: Maria
full_name: Ibáñez, Maria
id: 43C61214-F248-11E8-B48F-1D18A9856A87
last_name: Ibáñez
orcid: 0000-0001-5013-2843
- first_name: Chaoqi
full_name: Zhang, Chaoqi
last_name: Zhang
- first_name: Linlin
full_name: Yang, Linlin
last_name: Yang
- first_name: Yingtang
full_name: Zhou, Yingtang
last_name: Zhou
- first_name: Andreu
full_name: Cabot, Andreu
last_name: Cabot
citation:
ama: He R, Lee S, Ding Y, et al. Amorphous high entropy alloy nanosheets enabling
robust Li–S batteries. Advanced Functional Materials. 2025. doi:10.1002/adfm.202513859
apa: He, R., Lee, S., Ding, Y., Huang, C., Lu, X., Zheng, L., … Cabot, A. (2025).
Amorphous high entropy alloy nanosheets enabling robust Li–S batteries. Advanced
Functional Materials. Wiley. https://doi.org/10.1002/adfm.202513859
chicago: He, Ren, Seungho Lee, Yang Ding, Chen Huang, Xuan Lu, Lirong Zheng, Ao
Yu, et al. “Amorphous High Entropy Alloy Nanosheets Enabling Robust Li–S Batteries.”
Advanced Functional Materials. Wiley, 2025. https://doi.org/10.1002/adfm.202513859.
ieee: R. He et al., “Amorphous high entropy alloy nanosheets enabling robust
Li–S batteries,” Advanced Functional Materials. Wiley, 2025.
ista: He R, Lee S, Ding Y, Huang C, Lu X, Zheng L, Yu A, Zhang C, Li C, Bi X, Li
Y, Liao Y, Li J, Ostovari Moghaddam A, Yernar S, Xu Y, Ibáñez M, Zhang C, Yang
L, Zhou Y, Cabot A. 2025. Amorphous high entropy alloy nanosheets enabling robust
Li–S batteries. Advanced Functional Materials., e13859.
mla: He, Ren, et al. “Amorphous High Entropy Alloy Nanosheets Enabling Robust Li–S
Batteries.” Advanced Functional Materials, e13859, Wiley, 2025, doi:10.1002/adfm.202513859.
short: R. He, S. Lee, Y. Ding, C. Huang, X. Lu, L. Zheng, A. Yu, C. Zhang, C. Li,
X. Bi, Y. Li, Y. Liao, J. Li, A. Ostovari Moghaddam, S. Yernar, Y. Xu, M. Ibáñez,
C. Zhang, L. Yang, Y. Zhou, A. Cabot, Advanced Functional Materials (2025).
date_created: 2025-08-17T22:01:37Z
date_published: 2025-08-06T00:00:00Z
date_updated: 2025-09-30T14:20:56Z
day: '06'
ddc:
- '540'
department:
- _id: MaIb
doi: 10.1002/adfm.202513859
external_id:
isi:
- '001544757200001'
has_accepted_license: '1'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1002/adfm.202513859
month: '08'
oa: 1
oa_version: Published Version
project:
- _id: 9B8F7476-BA93-11EA-9121-9846C619BF3A
name: 'HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of
Semiconductors for Waste Heat Recovery'
publication: Advanced Functional Materials
publication_identifier:
eissn:
- 1616-3028
issn:
- 1616-301X
publication_status: epub_ahead
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Amorphous high entropy alloy nanosheets enabling robust Li–S batteries
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
year: '2025'
...
---
OA_place: publisher
OA_type: diamond
PlanS_conform: '1'
_id: '20192'
abstract:
- lang: eng
text: We study the physical origin and spectroscopic impact of extreme nebular emission
in high-redshift galaxies. The nebular continuum, which can appear during an extreme
starburst, is of particular importance as it tends to redden UV slopes and has
a significant contribution to the UV luminosities of galaxies. Furthermore, its
shape can be used to infer the gas density and temperature of the interstellar
medium. First, we provide a theoretical background, showing how different stellar
populations (SPS models, initial mass functions (IMFs), and stellar temperatures)
and nebular conditions impact observed galaxy spectra. We demonstrate that, for
systems with strong nebular continuum emission, 1) UV fluxes can increase by up
to 0.7~mag (or more in the case of hot/massive stars) above the stellar continuum,
which may help reconcile the surprising abundance of bright high-redshift galaxies
and the elevated UV luminosity density at z>10, 2) at high gas densities, UV slopes
can redden from \beta<-2.5 to \beta\sim-1, 3) observational measurements of \xi_{\rm
ion} are gross underestimates, and 4) UV downturns from two-photon emission can
masquerade as damped Ly\alpha systems. Second, we present a dataset of 58 galaxies
observed with NIRSpec on JWST at 2.510 galaxies, finding
that UV slopes and UV downturns are in some cases redder or steeper than expected
from SPS models, which may hint at more exotic (e.g. hotter/more massive stars
or AGN) ionizing sources.
acknowledgement: 'HK thanks Andrey Kravtsov for insightful comments and thoughtful
discussions. We sincerely thank the PIs and Co-Is of the JWST programs where spectral
data was made publicly available on the DJA. We refer interested readers to the
following papers for survey descriptions regarding the spectral data: Bunker et
al. (2023a); D’Eugenio et al. (2024); Bezanson et al. (2022); Barrufet et al. (2024);
de Graaff et al. (2024); Finkelstein et al. (2024); Glazebrook et al. (2024); Pierel
et al. (2024); Siebert et al. (2024); Maseda et al. (2024). This work is based in
part on observations made with the NASA/ESA/CSA James Webb Space Telescope. The
data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope
Science Institute, which is operated by the Association of Universities for Research
in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations
are associated with programs listed in Table 1. AJC and AS acknowledge funding from
the “FirstGalaxies” Advanced Grant from the European Research Council (ERC) under
the European Union’s Horizon 2020 research and innovation programme (Grant agreement
No. 789056). '
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Harley
full_name: Katz, Harley
last_name: Katz
- first_name: Alex J.
full_name: Cameron, Alex J.
last_name: Cameron
- first_name: Aayush
full_name: Saxena, Aayush
last_name: Saxena
- first_name: Laia
full_name: Barrufet, Laia
last_name: Barrufet
- first_name: Nicholas
full_name: Choustikov, Nicholas
last_name: Choustikov
- first_name: Nikko J.
full_name: Cleri, Nikko J.
last_name: Cleri
- first_name: Anna
full_name: De Graaff, Anna
last_name: De Graaff
- first_name: Richard S.
full_name: Ellis, Richard S.
last_name: Ellis
- first_name: Robert A.E.
full_name: Fosbury, Robert A.E.
last_name: Fosbury
- first_name: Kasper E.
full_name: Heintz, Kasper E.
last_name: Heintz
- first_name: Michael
full_name: Maseda, Michael
last_name: Maseda
- first_name: Jorryt J
full_name: Matthee, Jorryt J
id: 7439a258-f3c0-11ec-9501-9df22fe06720
last_name: Matthee
orcid: 0000-0003-2871-127X
- first_name: Ian
full_name: Mcconachie, Ian
last_name: Mcconachie
- first_name: Pascal A.
full_name: Oesch, Pascal A.
last_name: Oesch
citation:
ama: 'Katz H, Cameron AJ, Saxena A, et al. 21 Balmer Jump Street: The nebular continuum
at high redshift and implications for the bright galaxy problem, UV continuum
slopes, and early stellar populations. The Open Journal of Astrophysics.
2025;8. doi:10.33232/001c.142570'
apa: 'Katz, H., Cameron, A. J., Saxena, A., Barrufet, L., Choustikov, N., Cleri,
N. J., … Oesch, P. A. (2025). 21 Balmer Jump Street: The nebular continuum at
high redshift and implications for the bright galaxy problem, UV continuum slopes,
and early stellar populations. The Open Journal of Astrophysics. Maynooth
Academic Publishing. https://doi.org/10.33232/001c.142570'
chicago: 'Katz, Harley, Alex J. Cameron, Aayush Saxena, Laia Barrufet, Nicholas
Choustikov, Nikko J. Cleri, Anna De Graaff, et al. “21 Balmer Jump Street: The
Nebular Continuum at High Redshift and Implications for the Bright Galaxy Problem,
UV Continuum Slopes, and Early Stellar Populations.” The Open Journal of Astrophysics.
Maynooth Academic Publishing, 2025. https://doi.org/10.33232/001c.142570.'
ieee: 'H. Katz et al., “21 Balmer Jump Street: The nebular continuum at high
redshift and implications for the bright galaxy problem, UV continuum slopes,
and early stellar populations,” The Open Journal of Astrophysics, vol.
8. Maynooth Academic Publishing, 2025.'
ista: 'Katz H, Cameron AJ, Saxena A, Barrufet L, Choustikov N, Cleri NJ, De Graaff
A, Ellis RS, Fosbury RAE, Heintz KE, Maseda M, Matthee JJ, Mcconachie I, Oesch
PA. 2025. 21 Balmer Jump Street: The nebular continuum at high redshift and implications
for the bright galaxy problem, UV continuum slopes, and early stellar populations.
The Open Journal of Astrophysics. 8.'
mla: 'Katz, Harley, et al. “21 Balmer Jump Street: The Nebular Continuum at High
Redshift and Implications for the Bright Galaxy Problem, UV Continuum Slopes,
and Early Stellar Populations.” The Open Journal of Astrophysics, vol.
8, Maynooth Academic Publishing, 2025, doi:10.33232/001c.142570.'
short: H. Katz, A.J. Cameron, A. Saxena, L. Barrufet, N. Choustikov, N.J. Cleri,
A. De Graaff, R.S. Ellis, R.A.E. Fosbury, K.E. Heintz, M. Maseda, J.J. Matthee,
I. Mcconachie, P.A. Oesch, The Open Journal of Astrophysics 8 (2025).
date_created: 2025-08-17T22:01:37Z
date_published: 2025-07-25T00:00:00Z
date_updated: 2025-09-30T14:29:33Z
day: '25'
ddc:
- '520'
department:
- _id: JoMa
doi: 10.33232/001c.142570
external_id:
arxiv:
- '2408.03189'
file:
- access_level: open_access
checksum: ba469d132907147f9e86d87f9124dd14
content_type: application/pdf
creator: dernst
date_created: 2025-09-30T14:28:25Z
date_updated: 2025-09-30T14:28:25Z
file_id: '20412'
file_name: 2025_OpenJourAstrophysics_Katz.pdf
file_size: 1836432
relation: main_file
success: 1
file_date_updated: 2025-09-30T14:28:25Z
has_accepted_license: '1'
intvolume: ' 8'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
publication: The Open Journal of Astrophysics
publication_identifier:
eissn:
- 2565-6120
publication_status: published
publisher: Maynooth Academic Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: '21 Balmer Jump Street: The nebular continuum at high redshift and implications
for the bright galaxy problem, UV continuum slopes, and early stellar populations'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '20193'
abstract:
- lang: eng
text: Understanding the rapid formation of supermassive black holes in the early
Universe requires insights into stellar mass growth in host galaxies. Here we
present NIRSpec rest-frame optical spectra and NIRCam imaging from JWST of two
galaxies at z > 6, both hosting moderate-luminosity quasars. These galaxies exhibit
Balmer absorption lines, like low-redshift post-starburst galaxies. Our analyses
of the medium-resolution spectra and multiband photometry show that the bulk of
the stellar mass (log(M*/M☉) ≥ 10.6) formed in starburst episodes at redshift
9 and 7. One of the galaxies shows a clear Balmer break and lacks spatially resolved
Hα emission. It falls well below the star-formation main sequence at z = 6, indicating
quiescence. The other is transitioning to quiescence; together, these massive
galaxies are among the most distant post-starburst systems known. The blueshifted
wings of the quasar [O iii] emission lines indicate quasar-driven outflow, which
possibly influences star formation. Direct stellar velocity dispersion measurements
reveal that one galaxy follows the local black hole mass versus σ* relation whereas
the other is overmassive. The existence of massive post-starburst galaxies hosting
billion-solar-mass black holes in short-lived quasar phases indicates that supermassive
black holes and host galaxies played a principal role in each other’s rapid early
formation.
acknowledgement: We thank A. C. Carnall for supporting our use of Bagpipes. We thank
Y. Fu for his help on the use of QSOFitMORE. We thank J. Greene, S. Toft, T. Kakimoto
and M. Tanaka for fruitful discussions. This work is based on observations made
with the NASA/ESA/CSA JWST. The data were obtained from the Mikulski Archive for
Space Telescopes at the Space Telescope Science Institute, which is operated by
the Association of Universities for Research in Astronomy, under NASA contract NAS
5-03127 for JWST. These observations are associated with programmes GO 1967 and
GO 3859. Support for these programmes was provided by NASA through a grant from
the Space Telescope Science Institute. This work was supported by World Premier
International Research Center Initiative, MEXT, Japan. This work used computing
resources at Kavli IPMU. M.O., X.D., J.D.S., Y.M., T.I., K. Ito, K.K. and H.U. are
supported by the Japan Society for the Promotion of Science (KAKENHI Grant Numbers
JP24K22894, JP22K14071, JP18H01251, JP22H01262, JP21H04494, JP20K14531, JP23K13141,
JP17H06130 and JP20H01953). M.O. and K. Inayoshi acknowledge support from the National
Natural Science Foundation of China (Grant Numbers 12150410307, 12073003, 11721303,
11991052 and 11950410493). K. Inayoshi acknowledges support from the China Manned
Space Project (Grant Numbers CMS-CSST-2021-A04 and CMS-CSST-2021-A06). S.E.I.B.
is funded by the Deutsche Forschungsgemeinschaft (German Research Foundation) under
Emmy Noether Grant Number BO 5771/1-1. Z.H., T.T. and M.S. acknowledge support from
the NSF (Grant Numbers AST-2006176, AST-1907208 and AST-2006177). A.L. acknowledges
funding from MUR (Grant Number PRIN 2022935STW). B.T. acknowledges support from
the European Research Council (ERC) under the European Union’s Horizon 2020 research
and innovation programme (Grant Agreement Number 950533) and from the Israel Science
Foundation (Grant Number 1849/19). F. Walter acknowledges support from the ERC (Grant
Cosmic_gas). J.-T.S. is supported by the Deutsche Forschungsgemeinschaft (Project
Number 518006966). M.T. acknowledges support from the NWO (Grant Number 0.16.VIDI.189.162,
ODIN). S.F. acknowledges support from NASA through the NASA Hubble Fellowship (Grant
Number HST-HF2-51505.001-A awarded by the Space Telescope Science Institute). K.
Iwasawa acknowledges support under Grant Number PID2022-136827NB-C44 funded by MCIN/AEI/10.13039/501100011033
/FEDER, EU. M. Vestergaard gratefully acknowledges financial support from the Independent
Research Fund Denmark (Grant Numbers DFF 8021-00130 and 3103-00146). F. Wang acknowledges
support from the NSF (Award Number AST-2513040). R.B. is supported by the SNSF through
the Ambizione Grant PZ00P2_223532.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Masafusa
full_name: Onoue, Masafusa
last_name: Onoue
- first_name: Xuheng
full_name: Ding, Xuheng
last_name: Ding
- first_name: John D.
full_name: Silverman, John D.
last_name: Silverman
- first_name: Yoshiki
full_name: Matsuoka, Yoshiki
last_name: Matsuoka
- first_name: Takuma
full_name: Izumi, Takuma
last_name: Izumi
- first_name: Michael A.
full_name: Strauss, Michael A.
last_name: Strauss
- first_name: Charlotte
full_name: Ward, Charlotte
last_name: Ward
- first_name: Camryn L.
full_name: Phillips, Camryn L.
last_name: Phillips
- first_name: Kei
full_name: Ito, Kei
last_name: Ito
- first_name: Irham T.
full_name: Andika, Irham T.
last_name: Andika
- first_name: Kentaro
full_name: Aoki, Kentaro
last_name: Aoki
- first_name: Junya
full_name: Arita, Junya
last_name: Arita
- first_name: Shunsuke
full_name: Baba, Shunsuke
last_name: Baba
- first_name: Rebekka
full_name: Bieri, Rebekka
last_name: Bieri
- first_name: Sarah E.I.
full_name: Bosman, Sarah E.I.
last_name: Bosman
- first_name: Anna Christina
full_name: Eilers, Anna Christina
last_name: Eilers
- first_name: Seiji
full_name: Fujimoto, Seiji
last_name: Fujimoto
- first_name: Melanie
full_name: Habouzit, Melanie
last_name: Habouzit
- first_name: Zoltán
full_name: Haiman, Zoltán
id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
last_name: Haiman
orcid: 0000-0003-3633-5403
- first_name: Masatoshi
full_name: Imanishi, Masatoshi
last_name: Imanishi
- first_name: Kohei
full_name: Inayoshi, Kohei
last_name: Inayoshi
- first_name: Kazushi
full_name: Iwasawa, Kazushi
last_name: Iwasawa
- first_name: Knud
full_name: Jahnke, Knud
last_name: Jahnke
- first_name: Nobunari
full_name: Kashikawa, Nobunari
last_name: Kashikawa
- first_name: Toshihiro
full_name: Kawaguchi, Toshihiro
last_name: Kawaguchi
- first_name: Kotaro
full_name: Kohno, Kotaro
last_name: Kohno
- first_name: Chien Hsiu
full_name: Lee, Chien Hsiu
last_name: Lee
- first_name: Junyao
full_name: Li, Junyao
last_name: Li
- first_name: Alessandro
full_name: Lupi, Alessandro
last_name: Lupi
- first_name: Jianwei
full_name: Lyu, Jianwei
last_name: Lyu
- first_name: Tohru
full_name: Nagao, Tohru
last_name: Nagao
- first_name: Roderik
full_name: Overzier, Roderik
last_name: Overzier
- first_name: Jan Torge
full_name: Schindler, Jan Torge
last_name: Schindler
- first_name: Malte
full_name: Schramm, Malte
last_name: Schramm
- first_name: Matthew T.
full_name: Scoggins, Matthew T.
last_name: Scoggins
- first_name: Kazuhiro
full_name: Shimasaku, Kazuhiro
last_name: Shimasaku
- first_name: Yoshiki
full_name: Toba, Yoshiki
last_name: Toba
- first_name: Benny
full_name: Trakhtenbrot, Benny
last_name: Trakhtenbrot
- first_name: Maxime
full_name: Trebitsch, Maxime
last_name: Trebitsch
- first_name: Tommaso
full_name: Treu, Tommaso
last_name: Treu
- first_name: Hideki
full_name: Umehata, Hideki
last_name: Umehata
- first_name: Bram
full_name: Venemans, Bram
last_name: Venemans
- first_name: Marianne
full_name: Vestergaard, Marianne
last_name: Vestergaard
- first_name: Marta
full_name: Volonteri, Marta
last_name: Volonteri
- first_name: Fabian
full_name: Walter, Fabian
last_name: Walter
- first_name: Feige
full_name: Wang, Feige
last_name: Wang
- first_name: Jinyi
full_name: Yang, Jinyi
last_name: Yang
- first_name: Haowen
full_name: Zhang, Haowen
last_name: Zhang
citation:
ama: Onoue M, Ding X, Silverman JD, et al. A post-starburst pathway for the formation
of massive galaxies and black holes at z > 6. Nature Astronomy. 2025;9:1541-1552.
doi:10.1038/s41550-025-02628-1
apa: Onoue, M., Ding, X., Silverman, J. D., Matsuoka, Y., Izumi, T., Strauss, M.
A., … Zhang, H. (2025). A post-starburst pathway for the formation of massive
galaxies and black holes at z > 6. Nature Astronomy. Springer Nature.
https://doi.org/10.1038/s41550-025-02628-1
chicago: Onoue, Masafusa, Xuheng Ding, John D. Silverman, Yoshiki Matsuoka, Takuma
Izumi, Michael A. Strauss, Charlotte Ward, et al. “A Post-Starburst Pathway for
the Formation of Massive Galaxies and Black Holes at z > 6.” Nature Astronomy.
Springer Nature, 2025. https://doi.org/10.1038/s41550-025-02628-1.
ieee: M. Onoue et al., “A post-starburst pathway for the formation of massive
galaxies and black holes at z > 6,” Nature Astronomy, vol. 9. Springer
Nature, pp. 1541–1552, 2025.
ista: Onoue M, Ding X, Silverman JD, Matsuoka Y, Izumi T, Strauss MA, Ward C, Phillips
CL, Ito K, Andika IT, Aoki K, Arita J, Baba S, Bieri R, Bosman SEI, Eilers AC,
Fujimoto S, Habouzit M, Haiman Z, Imanishi M, Inayoshi K, Iwasawa K, Jahnke K,
Kashikawa N, Kawaguchi T, Kohno K, Lee CH, Li J, Lupi A, Lyu J, Nagao T, Overzier
R, Schindler JT, Schramm M, Scoggins MT, Shimasaku K, Toba Y, Trakhtenbrot B,
Trebitsch M, Treu T, Umehata H, Venemans B, Vestergaard M, Volonteri M, Walter
F, Wang F, Yang J, Zhang H. 2025. A post-starburst pathway for the formation of
massive galaxies and black holes at z > 6. Nature Astronomy. 9, 1541–1552.
mla: Onoue, Masafusa, et al. “A Post-Starburst Pathway for the Formation of Massive
Galaxies and Black Holes at z > 6.” Nature Astronomy, vol. 9, Springer
Nature, 2025, pp. 1541–52, doi:10.1038/s41550-025-02628-1.
short: M. Onoue, X. Ding, J.D. Silverman, Y. Matsuoka, T. Izumi, M.A. Strauss, C.
Ward, C.L. Phillips, K. Ito, I.T. Andika, K. Aoki, J. Arita, S. Baba, R. Bieri,
S.E.I. Bosman, A.C. Eilers, S. Fujimoto, M. Habouzit, Z. Haiman, M. Imanishi,
K. Inayoshi, K. Iwasawa, K. Jahnke, N. Kashikawa, T. Kawaguchi, K. Kohno, C.H.
Lee, J. Li, A. Lupi, J. Lyu, T. Nagao, R. Overzier, J.T. Schindler, M. Schramm,
M.T. Scoggins, K. Shimasaku, Y. Toba, B. Trakhtenbrot, M. Trebitsch, T. Treu,
H. Umehata, B. Venemans, M. Vestergaard, M. Volonteri, F. Walter, F. Wang, J.
Yang, H. Zhang, Nature Astronomy 9 (2025) 1541–1552.
date_created: 2025-08-17T22:01:38Z
date_published: 2025-10-01T00:00:00Z
date_updated: 2025-12-30T13:08:12Z
day: '01'
department:
- _id: ZoHa
doi: 10.1038/s41550-025-02628-1
external_id:
arxiv:
- '2409.07113'
isi:
- '001548138600001'
intvolume: ' 9'
isi: 1
language:
- iso: eng
main_file_link:
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url: https://arxiv.org/abs/2409.07113
month: '10'
oa: 1
oa_version: Preprint
page: 1541-1552
publication: Nature Astronomy
publication_identifier:
eissn:
- 2397-3366
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: A post-starburst pathway for the formation of massive galaxies and black holes
at z > 6
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2025'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '20217'
abstract:
- lang: eng
text: "We present Virgil, a Mid-Infrared Instrument (MIRI) extremely red object
detected with the F1000W filter as part of the MIRI Deep Imaging Survey observations
of the Hubble Ultra Deep Field. Virgil is an Lyα emitter (LAE) at zspec = 6.6312
± 0.0019 (from the Very Large Telescope/MUSE) with a rest-frame UV-to-optical
spectral energy distribution (SED) typical of LAEs at similar redshifts. However,
MIRI observations reveal an unexpected extremely red color at rest-frame near-infrared
(NIR) wavelengths, F444W − F1000W = 2.33 ± 0.06. Such a steep\r\nrise in the NIR,
completely missed without MIRI imaging, is poorly reproduced by models including
only stellar populations and hints toward the presence of an active galactic nucleus,
although alternative explanations such as extreme dust obscuration and strong
nebular continuum and emission lines contribution due to young stellar ages cannot
be completely ruled out. According to the shape of its overall SED, Virgil belongs
to the recently discovered\r\npopulation of little red dots but displays an extended
rest-frame UV-optical wavelength morphology following a 2DSérsic profile with
an average index of n = 0.93+0.85_0.31 and re = 0.49+0.05_0.11 pkpc. Only at
MIRI wavelengths, Virgil is unresolved due to the coarser point-spread function.
This discovery demonstrates the crucial importance of deep MIRI surveys to reveal
the true nature and properties of high-z galaxies that otherwise would be misinterpreted
and raises the question of how common Virgil-like objects could be in the early
Universe."
acknowledgement: "The authors thank R. Cooper, G. Yang, V. Kokorev, D. Wen, C. Williams,
and H. Übler for useful discussions and comments.\r\nE.I. and K.I.C. acknowledge
funding from the Netherlands Research School for Astronomy (NOVA). K.I.C. acknowledges
funding from the Dutch Research Council (NWO) through the award of the Vici grant
VI.C.212.036. A.A.-H. acknowledges support from grant PID2021-124665NB-I00 funded
by MCIN/AEI/10.13039/ 501100011033 and by “ERDF A way of making Europe.” P.G.P.-G.
acknowledges support from grant PID2022-139567NB-I00 funded by the Spanish Ministerio
de Ciencia e Innovación MCIN/AEI/10.13039/501100011033, FEDER Una manera de hacer
Europa. J.A.-M., A.C.-G., and L.C. acknowledge support by grant PIB2021-127718NB-100
from the Spanish Ministry of Science and Innovation/State Agency of Research MCIN/AEI/10.13039/501100011033
and by “ERDF A way of making Europe.” L.C. thanks the support from the Cosmic Dawn
Center received during visits to DAWN as an international associate. L.C. acknowledges
support by grants PIB2021-127718NB-100 and PID2022-139567NB-I00 from the Spanish
Ministry of Science and Innovation/State Agency of Research MCIN/AEI/10.13039/501100011033
and by “ERDF A way of making Europe.” T.R.G. acknowledges support from the Carlsberg
Foundation (grant No. CF20-0534). S.G. acknowledges financial support from the Cosmic
Dawn Center (DAWN), funded by the Danish National Research Foundation (DNRF) under
grant No. 140. This work was supported by research grants (VIL16599, VIL54489) from
VILLUM FONDEN. J.P.P. and T.V.T. acknowledge financial support from the UK Science
and Technology Facilities Council and the UK Space Agency.\r\n\r\nThis work is based
on observations made with the NASA/ESA/CSA James Webb Space Telescope. The data
were obtained from the MAST at the Space Telescope Science Institute, which is operated
by the Association of Universities for Research in Astronomy, Inc., under NASA contract
NAS 5-03127 for JWST. These observations are associated with programs GO #1963,
GO #1895, and GTO #1283. The authors acknowledge the team led by co-PIs: C. Williams,
M. Maseda, and S. Tacchella, and PI P. Oesch, for developing their respective observing
programs with a zero-exclusive-access period. Also based on observations made with
the NASA/ESA HST obtained from the Space Telescope Science Institute, which is operated
by the Association of Universities for Research in Astronomy, Inc., under NASA contract
NAS 5-26555. The work presented here is the effort of the entire MIRI team, and
the enthusiasm within the MIRI partnership is a significant factor in its success.
MIRI draws on the scientific and technical expertise of the following organizations:
Ames Research Center, USA; Airbus Defence and Space, UK; CEA-Irfu, Saclay, France;
Centre Spatial de Liège, Belgium; Consejo Superior de Investigaciones Científicas,
Spain; Carl Zeiss Optronics, Germany; Chalmers University of Technology, Sweden;
Danish Space Research Institute, Denmark; Dublin Institute for Advanced Studies,
Ireland; European Space Agency, Netherlands; ETCA, Belgium; ETH Zurich, Switzerland;
Goddard Space Flight Center, USA; Institute d’Astrophysique Spatiale, France; Instituto
Nacional de Técnica Aeroespacial, Spain; Institute for Astronomy, Edinburgh, UK;
Jet Propulsion Laboratory, USA; Laboratoire d’Astrophysique de Marseille (LAM),
France; Leiden University, Netherlands; Lockheed Advanced Technology Center (USA);
NOVA Opt-IR group at Dwingeloo, Netherlands; Northrop Grumman, USA; Max-Planck Institut
für Astronomie (MPIA), Heidelberg, Germany; Laboratoire d’Etudes Spatiales et d’Instrumentation
en Astrophysique (LESIA), France; Paul Scherrer Institut, Switzerland; Raytheon
Vision Systems, USA; RUAG Aerospace, Switzerland; Rutherford Appleton Laboratory
(RAL Space), UK; Space Telescope Science Institute, USA; Toegepast-Natuurwetenschappelijk
Onderzoek (TNO-TPD), Netherlands; UK Astronomy Technology Centre, UK; University
College London, UK; University of Amsterdam, Netherlands; University of Arizona,
USA; University of Cardiff, UK; University of Cologne, Germany; University of Ghent;
University of Groningen, Netherlands; University of Leicester, UK; University of
Leuven, Belgium; University of Stockholm, Sweden; Utah State University, USA.\r\nFor
the purpose of open access, the author has applied a Creative Commons Attribution
(CC BY) licence to the Author Accepted Manuscript version arising from this submission."
article_number: '160'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Edoardo
full_name: Iani, Edoardo
id: 4053390a-6b68-11ef-9828-a3b8adef8d0a
last_name: Iani
orcid: 0000-0001-8386-3546
- first_name: Pierluigi
full_name: Rinaldi, Pierluigi
last_name: Rinaldi
- first_name: Karina I.
full_name: Caputi, Karina I.
last_name: Caputi
- first_name: Marianna
full_name: Annunziatella, Marianna
last_name: Annunziatella
- first_name: Danial
full_name: Langeroodi, Danial
last_name: Langeroodi
- first_name: Jens
full_name: Melinder, Jens
last_name: Melinder
- first_name: Pablo G.
full_name: Pérez-González, Pablo G.
last_name: Pérez-González
- first_name: Javier
full_name: Álvarez-Márquez, Javier
last_name: Álvarez-Márquez
- first_name: Leindert A.
full_name: Boogaard, Leindert A.
last_name: Boogaard
- first_name: Sarah E.I.
full_name: Bosman, Sarah E.I.
last_name: Bosman
- first_name: Luca
full_name: Costantin, Luca
last_name: Costantin
- first_name: Thibaud
full_name: Moutard, Thibaud
last_name: Moutard
- first_name: Luis
full_name: Colina, Luis
last_name: Colina
- first_name: Göran
full_name: Östlin, Göran
last_name: Östlin
- first_name: Thomas R.
full_name: Greve, Thomas R.
last_name: Greve
- first_name: Gillian
full_name: Wright, Gillian
last_name: Wright
- first_name: Almudena
full_name: Alonso-Herrero, Almudena
last_name: Alonso-Herrero
- first_name: Arjan
full_name: Bik, Arjan
last_name: Bik
- first_name: Steven
full_name: Gillman, Steven
last_name: Gillman
- first_name: Alejandro
full_name: Crespo Gómez, Alejandro
last_name: Crespo Gómez
- first_name: Jens
full_name: Hjorth, Jens
last_name: Hjorth
- first_name: Sarah
full_name: Kendrew, Sarah
last_name: Kendrew
- first_name: Alvaro
full_name: Labiano, Alvaro
last_name: Labiano
- first_name: John P.
full_name: Pye, John P.
last_name: Pye
- first_name: Tuomo V.
full_name: Tikkanen, Tuomo V.
last_name: Tikkanen
- first_name: Fabian
full_name: Walter, Fabian
last_name: Walter
- first_name: Manuel
full_name: Güdel, Manuel
last_name: Güdel
- first_name: Thomas
full_name: Henning, Thomas
last_name: Henning
- first_name: Paul P.
full_name: Van Der Werf, Paul P.
last_name: Van Der Werf
citation:
ama: 'Iani E, Rinaldi P, Caputi KI, et al. MIDIS: MIRI uncovers Virgil, the first
Little Red Dot with clear detection of its host galaxy at z ≃ 6.6. The Astrophysical
Journal. 2025;989(2). doi:10.3847/1538-4357/ade5a6'
apa: 'Iani, E., Rinaldi, P., Caputi, K. I., Annunziatella, M., Langeroodi, D., Melinder,
J., … Van Der Werf, P. P. (2025). MIDIS: MIRI uncovers Virgil, the first Little
Red Dot with clear detection of its host galaxy at z ≃ 6.6. The Astrophysical
Journal. IOP Publishing. https://doi.org/10.3847/1538-4357/ade5a6'
chicago: 'Iani, Edoardo, Pierluigi Rinaldi, Karina I. Caputi, Marianna Annunziatella,
Danial Langeroodi, Jens Melinder, Pablo G. Pérez-González, et al. “MIDIS: MIRI
Uncovers Virgil, the First Little Red Dot with Clear Detection of Its Host Galaxy
at z ≃ 6.6.” The Astrophysical Journal. IOP Publishing, 2025. https://doi.org/10.3847/1538-4357/ade5a6.'
ieee: 'E. Iani et al., “MIDIS: MIRI uncovers Virgil, the first Little Red
Dot with clear detection of its host galaxy at z ≃ 6.6,” The Astrophysical
Journal, vol. 989, no. 2. IOP Publishing, 2025.'
ista: 'Iani E, Rinaldi P, Caputi KI, Annunziatella M, Langeroodi D, Melinder J,
Pérez-González PG, Álvarez-Márquez J, Boogaard LA, Bosman SEI, Costantin L, Moutard
T, Colina L, Östlin G, Greve TR, Wright G, Alonso-Herrero A, Bik A, Gillman S,
Crespo Gómez A, Hjorth J, Kendrew S, Labiano A, Pye JP, Tikkanen TV, Walter F,
Güdel M, Henning T, Van Der Werf PP. 2025. MIDIS: MIRI uncovers Virgil, the first
Little Red Dot with clear detection of its host galaxy at z ≃ 6.6. The Astrophysical
Journal. 989(2), 160.'
mla: 'Iani, Edoardo, et al. “MIDIS: MIRI Uncovers Virgil, the First Little Red Dot
with Clear Detection of Its Host Galaxy at z ≃ 6.6.” The Astrophysical Journal,
vol. 989, no. 2, 160, IOP Publishing, 2025, doi:10.3847/1538-4357/ade5a6.'
short: E. Iani, P. Rinaldi, K.I. Caputi, M. Annunziatella, D. Langeroodi, J. Melinder,
P.G. Pérez-González, J. Álvarez-Márquez, L.A. Boogaard, S.E.I. Bosman, L. Costantin,
T. Moutard, L. Colina, G. Östlin, T.R. Greve, G. Wright, A. Alonso-Herrero, A.
Bik, S. Gillman, A. Crespo Gómez, J. Hjorth, S. Kendrew, A. Labiano, J.P. Pye,
T.V. Tikkanen, F. Walter, M. Güdel, T. Henning, P.P. Van Der Werf, The Astrophysical
Journal 989 (2025).
date_created: 2025-08-24T22:01:29Z
date_published: 2025-08-20T00:00:00Z
date_updated: 2026-02-16T12:43:12Z
day: '20'
ddc:
- '520'
department:
- _id: JoMa
doi: 10.3847/1538-4357/ade5a6
external_id:
arxiv:
- '2406.18207'
isi:
- '001548132000001'
file:
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checksum: 92196e8352dddb1f305c253da1996ab6
content_type: application/pdf
creator: dernst
date_created: 2025-09-02T06:40:23Z
date_updated: 2025-09-02T06:40:23Z
file_id: '20268'
file_name: 2025_AstrophysicalJour_Iani.pdf
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relation: main_file
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month: '08'
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oa_version: Published Version
publication: The Astrophysical Journal
publication_identifier:
eissn:
- 1538-4357
issn:
- 0004-637X
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'MIDIS: MIRI uncovers Virgil, the first Little Red Dot with clear detection
of its host galaxy at z ≃ 6.6'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 989
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20218'
abstract:
- lang: eng
text: Humanity has long sought inspiration from nature to innovate materials and
devices. As science advances, nature-inspired materials are becoming part of our
lives. Animate materials, characterized by their activity, adaptability, and autonomy,
emulate properties of living systems. While only biological materials fully embody
these principles, artificial versions are advancing rapidly, promising transformative
impacts in the circular economy, health and climate resilience within a generation.
This roadmap presents authoritative perspectives on animate materials across different
disciplines and scales, highlighting their interdisciplinary nature and potential
applications in diverse fields including nanotechnology, robotics and the built
environment. It underscores the need for concerted efforts to address shared challenges
such as complexity management, scalability, evolvability, interdisciplinary collaboration,
and ethical and environmental considerations. The framework defined by classifying
materials based on their level of animacy can guide this emerging field to encourage
cooperation and responsible development. By unravelling the mysteries of living
matter and leveraging its principles, we can design materials and systems that
will transform our world in a more sustainable manner.
acknowledgement: "Living Architecture is Funded by the EU Horizon 2020 Future Emerging
Technologies Open programme (2016–2019) Grant Agreement 686585 a consortium of 6
collaborating institutions—Newcastle University, University of Trento, University
of the West of England, Spanish National Research Council, Explora Biotech and Liquifer
Systems Group.\r\n\r\nThe Active Living Infrastructure: Controlled Environment (ALICE)
project is funded by an EU Innovation Award for the development of a bio-digital
‘brick’ prototype, a collaboration between Newcastle University, Translating Nature,
and the University of the West of England (2019–2021) under EU Grant Agreement No.
851246.\r\n\r\nMicrobial Hydroponics: Circular Sustainable Electrobiosynthesis (Mi-Hy)
is Funded by the European Union under Grant Agreement Number 101114746, which is
a collaboration between Beneficiaries, KU Leuven (Belgium), the University of Southampton
(UK), SONY Computer Science Laboratory (France), BioFaction KG (Austria), Spanish
National Research Council (Spain), and Associated Partners, the University of the
West of England (UK) and University of Southampton (UK). Mi-Hy is also supported
through the interdisciplinary KU Leuven Institute for Cultural Heritage (HERKUL)."
article_number: '333501'
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Giorgio
full_name: Volpe, Giorgio
last_name: Volpe
- first_name: Nuno A.M.
full_name: Araújo, Nuno A.M.
last_name: Araújo
- first_name: Maria
full_name: Guix, Maria
last_name: Guix
- first_name: Mark
full_name: Miodownik, Mark
last_name: Miodownik
- first_name: Nicolas
full_name: Martin, Nicolas
last_name: Martin
- first_name: Laura
full_name: Alvarez, Laura
last_name: Alvarez
- first_name: Juliane
full_name: Simmchen, Juliane
last_name: Simmchen
- first_name: Roberto Di
full_name: Leonardo, Roberto Di
last_name: Leonardo
- first_name: Nicola
full_name: Pellicciotta, Nicola
last_name: Pellicciotta
- first_name: Quentin
full_name: Martinet, Quentin
id: b37485a8-d343-11eb-a0e9-df8c484ef8ab
last_name: Martinet
orcid: 0000-0002-2916-6632
- first_name: Jérémie A
full_name: Palacci, Jérémie A
id: 8fb92548-2b22-11eb-b7c1-a3f0d08d7c7d
last_name: Palacci
orcid: 0000-0002-7253-9465
- first_name: Wai Kit
full_name: Ng, Wai Kit
last_name: Ng
- first_name: Dhruv
full_name: Saxena, Dhruv
last_name: Saxena
- first_name: Riccardo
full_name: Sapienza, Riccardo
last_name: Sapienza
- first_name: Sara
full_name: Nadine, Sara
last_name: Nadine
- first_name: João F.
full_name: Mano, João F.
last_name: Mano
- first_name: Reza
full_name: Mahdavi, Reza
last_name: Mahdavi
- first_name: Caroline
full_name: Beck Adiels, Caroline
last_name: Beck Adiels
- first_name: Joe
full_name: Forth, Joe
last_name: Forth
- first_name: Christian
full_name: Santangelo, Christian
last_name: Santangelo
- first_name: Stefano
full_name: Palagi, Stefano
last_name: Palagi
- first_name: Ji Min
full_name: Seok, Ji Min
last_name: Seok
- first_name: Victoria A.
full_name: Webster-Wood, Victoria A.
last_name: Webster-Wood
- first_name: Shuhong
full_name: Wang, Shuhong
last_name: Wang
- first_name: Lining
full_name: Yao, Lining
last_name: Yao
- first_name: Amirreza
full_name: Aghakhani, Amirreza
last_name: Aghakhani
- first_name: Thomas
full_name: Barois, Thomas
last_name: Barois
- first_name: Hamid
full_name: Kellay, Hamid
last_name: Kellay
- first_name: Corentin
full_name: Coulais, Corentin
last_name: Coulais
- first_name: Martin
full_name: Van Hecke, Martin
last_name: Van Hecke
- first_name: Christopher J.
full_name: Pierce, Christopher J.
last_name: Pierce
- first_name: Tianyu
full_name: Wang, Tianyu
last_name: Wang
- first_name: Baxi
full_name: Chong, Baxi
last_name: Chong
- first_name: Daniel I.
full_name: Goldman, Daniel I.
last_name: Goldman
- first_name: Andreagiovanni
full_name: Reina, Andreagiovanni
last_name: Reina
- first_name: Vito
full_name: Trianni, Vito
last_name: Trianni
- first_name: Giovanni
full_name: Volpe, Giovanni
last_name: Volpe
- first_name: Richard
full_name: Beckett, Richard
last_name: Beckett
- first_name: Sean P.
full_name: Nair, Sean P.
last_name: Nair
- first_name: Rachel
full_name: Armstrong, Rachel
last_name: Armstrong
citation:
ama: Volpe G, Araújo NAM, Guix M, et al. Roadmap for animate matter. Journal
of Physics Condensed Matter. 2025;37(33). doi:10.1088/1361-648X/adebd3
apa: Volpe, G., Araújo, N. A. M., Guix, M., Miodownik, M., Martin, N., Alvarez,
L., … Armstrong, R. (2025). Roadmap for animate matter. Journal of Physics
Condensed Matter. IOP Publishing. https://doi.org/10.1088/1361-648X/adebd3
chicago: Volpe, Giorgio, Nuno A.M. Araújo, Maria Guix, Mark Miodownik, Nicolas Martin,
Laura Alvarez, Juliane Simmchen, et al. “Roadmap for Animate Matter.” Journal
of Physics Condensed Matter. IOP Publishing, 2025. https://doi.org/10.1088/1361-648X/adebd3.
ieee: G. Volpe et al., “Roadmap for animate matter,” Journal of Physics
Condensed Matter, vol. 37, no. 33. IOP Publishing, 2025.
ista: Volpe G, Araújo NAM, Guix M, Miodownik M, Martin N, Alvarez L, Simmchen J,
Leonardo RD, Pellicciotta N, Martinet Q, Palacci JA, Ng WK, Saxena D, Sapienza
R, Nadine S, Mano JF, Mahdavi R, Beck Adiels C, Forth J, Santangelo C, Palagi
S, Seok JM, Webster-Wood VA, Wang S, Yao L, Aghakhani A, Barois T, Kellay H, Coulais
C, Van Hecke M, Pierce CJ, Wang T, Chong B, Goldman DI, Reina A, Trianni V, Volpe
G, Beckett R, Nair SP, Armstrong R. 2025. Roadmap for animate matter. Journal
of Physics Condensed Matter. 37(33), 333501.
mla: Volpe, Giorgio, et al. “Roadmap for Animate Matter.” Journal of Physics
Condensed Matter, vol. 37, no. 33, 333501, IOP Publishing, 2025, doi:10.1088/1361-648X/adebd3.
short: G. Volpe, N.A.M. Araújo, M. Guix, M. Miodownik, N. Martin, L. Alvarez, J.
Simmchen, R.D. Leonardo, N. Pellicciotta, Q. Martinet, J.A. Palacci, W.K. Ng,
D. Saxena, R. Sapienza, S. Nadine, J.F. Mano, R. Mahdavi, C. Beck Adiels, J. Forth,
C. Santangelo, S. Palagi, J.M. Seok, V.A. Webster-Wood, S. Wang, L. Yao, A. Aghakhani,
T. Barois, H. Kellay, C. Coulais, M. Van Hecke, C.J. Pierce, T. Wang, B. Chong,
D.I. Goldman, A. Reina, V. Trianni, G. Volpe, R. Beckett, S.P. Nair, R. Armstrong,
Journal of Physics Condensed Matter 37 (2025).
date_created: 2025-08-24T22:01:30Z
date_published: 2025-08-18T00:00:00Z
date_updated: 2025-09-30T14:25:12Z
day: '18'
ddc:
- '530'
department:
- _id: JePa
doi: 10.1088/1361-648X/adebd3
external_id:
arxiv:
- '2407.10623'
isi:
- '001550090200001'
file:
- access_level: open_access
checksum: 7309274f78bed785b158bd290337f456
content_type: application/pdf
creator: dernst
date_created: 2025-09-02T07:22:48Z
date_updated: 2025-09-02T07:22:48Z
file_id: '20271'
file_name: 2025_CondensedMatter_Volpe.pdf
file_size: 8997829
relation: main_file
success: 1
file_date_updated: 2025-09-02T07:22:48Z
has_accepted_license: '1'
intvolume: ' 37'
isi: 1
issue: '33'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
publication: Journal of Physics Condensed Matter
publication_identifier:
eissn:
- 1361-648X
issn:
- 0953-8984
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: Roadmap for animate matter
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 37
year: '2025'
...
---
OA_type: closed access
_id: '20219'
abstract:
- lang: eng
text: Reproduction is a fundamental biological process, with organisms reproducing
sexually, asexually, and, in some cases, utilizing both modes of reproduction
within the same population. Does the ability to reproduce through a combination
of asexual and sexual modes offer an evolutionary advantage over relying on either
mode alone? Here, we introduce an empirically driven theoretical model to examine
the dynamics and interplay between sexual and asexual reproduction in stick insect
populations. We analyse it using a novel phase transition approach and corroborate
it using published experimental data. We find that the presence of males can either
increase or decrease the overall population size. However, maintaining an optimal
ratio of parthenogenetic to sexual reproduction is crucial for male resilience,
effectively delaying male extinction. Conversely, extreme levels of parthenogenetic
reproduction—whether too high or too low—can lead to male extinction, emphasizing
the need for a balanced number of virgin females to ensure the persistence of
males. Our model also explains male absence in Carausius morosus and persistence
in Extatosoma tiaratum. Our findings provide valuable insights into the interplay
of reproductive strategies and contribute to broader discussions on the transitions
between sexual and asexual reproduction.
acknowledgement: We acknowledge Prof. Uri Alon for introducing us to the topic of
systems biology during the graduate course at the Weizmann Institute of Science,
whose insights and teachings have greatly inspired this work.
article_number: '20250202'
article_processing_charge: No
article_type: original
author:
- first_name: Oran
full_name: Ayalon, Oran
last_name: Ayalon
- first_name: Harikrishnan
full_name: Rajendran, Harikrishnan
id: 876b6b34-8ff4-11ec-97c9-8d95a7aae416
last_name: Rajendran
citation:
ama: Ayalon O, Rajendran H. Interplay of asexual and sexual reproduction in bifunctional
insects. Journal of the Royal Society Interface. 2025;22(229). doi:10.1098/rsif.2025.0202
apa: Ayalon, O., & Rajendran, H. (2025). Interplay of asexual and sexual reproduction
in bifunctional insects. Journal of the Royal Society Interface. The Royal
Society. https://doi.org/10.1098/rsif.2025.0202
chicago: Ayalon, Oran, and Harikrishnan Rajendran. “Interplay of Asexual and Sexual
Reproduction in Bifunctional Insects.” Journal of the Royal Society Interface.
The Royal Society, 2025. https://doi.org/10.1098/rsif.2025.0202.
ieee: O. Ayalon and H. Rajendran, “Interplay of asexual and sexual reproduction
in bifunctional insects,” Journal of the Royal Society Interface, vol.
22, no. 229. The Royal Society, 2025.
ista: Ayalon O, Rajendran H. 2025. Interplay of asexual and sexual reproduction
in bifunctional insects. Journal of the Royal Society Interface. 22(229), 20250202.
mla: Ayalon, Oran, and Harikrishnan Rajendran. “Interplay of Asexual and Sexual
Reproduction in Bifunctional Insects.” Journal of the Royal Society Interface,
vol. 22, no. 229, 20250202, The Royal Society, 2025, doi:10.1098/rsif.2025.0202.
short: O. Ayalon, H. Rajendran, Journal of the Royal Society Interface 22 (2025).
corr_author: '1'
date_created: 2025-08-24T22:01:30Z
date_published: 2025-08-13T00:00:00Z
date_updated: 2025-09-30T14:24:40Z
day: '13'
department:
- _id: SyCr
doi: 10.1098/rsif.2025.0202
external_id:
isi:
- '001548084900001'
pmid:
- '40799050'
intvolume: ' 22'
isi: 1
issue: '229'
language:
- iso: eng
month: '08'
oa_version: None
pmid: 1
publication: Journal of the Royal Society Interface
publication_identifier:
eissn:
- 1742-5662
issn:
- 1742-5689
publication_status: published
publisher: The Royal Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Interplay of asexual and sexual reproduction in bifunctional insects
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 22
year: '2025'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '20220'
abstract:
- lang: eng
text: Stress granules (SG) are biomolecular condensates that represent an adaptive
response of cells to various stresses, including heat. However, the cell type–specific
function and relevance of SG formation, especially during reproductive development,
are largely not understood. Here, we show that the meiotic A-type cyclin TARDY
ASYNCHRONOUS MEIOSIS (TAM) is recruited to SGs in male meiocytes of Arabidopsis
after exposure to heat. We find that the amino terminus of TAM is necessary and
sufficient for the localization of proteins to meiotic SGs. Swapping the amino
terminus of TAM with the one of its sister protein CYCA1;1 resulted in a separation-of-function
allele of TAM, which prevents the partitioning of TAM to SGs while restoring a
wild-type phenotype in a tam mutant background under nonheat stress conditions.
Notably, plants expressing this TAM version prematurely terminate meiosis under
heat resulting in unreduced gametes. Thus, the formation of TAM-containing SGs
is necessary for genome stability under heat stress.
acknowledged_ssus:
- _id: Bio
acknowledgement: "We thank L. Strader (Duke University, Durham) and A. Holehouse (Washington
University, Saint Louis) for discussion and input in LLPS. We thank T. Nakagawa
(Shimane University, Matsue) for providing the pGWB604 Gateway vector containing
bar gene identified by Meiji Seika Kaisha Ltd. We thank M. Heese (Hamburg University)
for the critical reading and comments on this manuscript. We further thank J. Mehrmann
(Hamburg University) for technical assistance. We thank the ISTA imaging facility
for assistance for microscopy.\r\nThis project has received funding from JST-PRESTO
(JPMJPR18H7), JST-CREST (JPMJCR18H4), European Union’s Horizon 2020 under MSCA grant
101034413, and a federal grant from the state of Hamburg (LFF-BiCon)."
article_processing_charge: Yes
article_type: original
author:
- first_name: Joke G
full_name: De Jaeger-Braet, Joke G
id: 26bd38d3-c59a-11ee-a1af-d7a988cafcc5
last_name: De Jaeger-Braet
- first_name: Merle
full_name: Hartmann, Merle
last_name: Hartmann
- first_name: Lev
full_name: Böttger, Lev
last_name: Böttger
- first_name: Chao
full_name: Yang, Chao
id: 082e3e6e-8069-11ed-8390-c8cce7b1aaca
last_name: Yang
- first_name: Takahiro
full_name: Hamada, Takahiro
last_name: Hamada
- first_name: Stefan
full_name: Hoth, Stefan
last_name: Hoth
- first_name: Xiaoqi
full_name: Feng, Xiaoqi
id: e0164712-22ee-11ed-b12a-d80fcdf35958
last_name: Feng
orcid: 0000-0002-4008-1234
- first_name: Magdalena
full_name: Weingartner, Magdalena
last_name: Weingartner
- first_name: Arp
full_name: Schnittger, Arp
last_name: Schnittger
citation:
ama: De Jaeger-Braet JG, Hartmann M, Böttger L, et al. The recruitment of the A-type
cyclin TAM to stress granules is crucial for meiotic fidelity under heat. Science
Advances. 2025;11(32):eadr5694. doi:10.1126/sciadv.adr5694
apa: De Jaeger-Braet, J. G., Hartmann, M., Böttger, L., Yang, C., Hamada, T., Hoth,
S., … Schnittger, A. (2025). The recruitment of the A-type cyclin TAM to stress
granules is crucial for meiotic fidelity under heat. Science Advances.
AAAS. https://doi.org/10.1126/sciadv.adr5694
chicago: De Jaeger-Braet, Joke G, Merle Hartmann, Lev Böttger, Chao Yang, Takahiro
Hamada, Stefan Hoth, Xiaoqi Feng, Magdalena Weingartner, and Arp Schnittger. “The
Recruitment of the A-Type Cyclin TAM to Stress Granules Is Crucial for Meiotic
Fidelity under Heat.” Science Advances. AAAS, 2025. https://doi.org/10.1126/sciadv.adr5694.
ieee: J. G. De Jaeger-Braet et al., “The recruitment of the A-type cyclin
TAM to stress granules is crucial for meiotic fidelity under heat,” Science
Advances, vol. 11, no. 32. AAAS, p. eadr5694, 2025.
ista: De Jaeger-Braet JG, Hartmann M, Böttger L, Yang C, Hamada T, Hoth S, Feng
X, Weingartner M, Schnittger A. 2025. The recruitment of the A-type cyclin TAM
to stress granules is crucial for meiotic fidelity under heat. Science Advances.
11(32), eadr5694.
mla: De Jaeger-Braet, Joke G., et al. “The Recruitment of the A-Type Cyclin TAM
to Stress Granules Is Crucial for Meiotic Fidelity under Heat.” Science Advances,
vol. 11, no. 32, AAAS, 2025, p. eadr5694, doi:10.1126/sciadv.adr5694.
short: J.G. De Jaeger-Braet, M. Hartmann, L. Böttger, C. Yang, T. Hamada, S. Hoth,
X. Feng, M. Weingartner, A. Schnittger, Science Advances 11 (2025) eadr5694.
date_created: 2025-08-24T22:01:30Z
date_published: 2025-08-08T00:00:00Z
date_updated: 2025-09-30T14:24:10Z
day: '08'
ddc:
- '580'
department:
- _id: XiFe
doi: 10.1126/sciadv.adr5694
ec_funded: 1
external_id:
isi:
- '001549102600016'
file:
- access_level: open_access
checksum: 0f1ae246acc9b075f01bf4afe382c8ba
content_type: application/pdf
creator: dernst
date_created: 2025-09-02T07:05:37Z
date_updated: 2025-09-02T07:05:37Z
file_id: '20270'
file_name: 2025_ScienceAdvance_DeJaegerBraet.pdf
file_size: 10876817
relation: main_file
success: 1
file_date_updated: 2025-09-02T07:05:37Z
has_accepted_license: '1'
intvolume: ' 11'
isi: 1
issue: '32'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/4.0/
month: '08'
oa: 1
oa_version: Published Version
page: eadr5694
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
call_identifier: H2020
grant_number: '101034413'
name: 'IST-BRIDGE: International postdoctoral program'
publication: Science Advances
publication_identifier:
eissn:
- 2375-2548
publication_status: published
publisher: AAAS
quality_controlled: '1'
scopus_import: '1'
status: public
title: The recruitment of the A-type cyclin TAM to stress granules is crucial for
meiotic fidelity under heat
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 11
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20221'
abstract:
- lang: eng
text: We describe the design, synthesis, and single-molecule junction conductance
of π-electron molecules bearing both radial and linear π-conjugation pathways,
whereby cycloparaphenylene (CPP) radial cores are π-extended linearly with aryl
alkyne substituents as models for previously reported CPP-arylene ethynylene conjugated
polymers. Although radially and linearly conjugated molecules have been studied
previously in isolation as junction-bridging molecular electronic units, this
is the first study to examine molecules where both topologies are operative. Our
results reveal that the presence of radial CPP components within the junction-spanning
pathway leads to a reduction in the conductance of the backbone compared to model
linear phenyl substituents. Through tight-binding and DFT-based calculations,
we attribute this conductance change to intramolecular van der Waals (vdW) interactions
between the CPP ring and the junction-spanning arylene-ethynylene molecular backbone.
These interactions induce changes in the dihedral angles of the backbone, leading
to a reduced overlap of π orbitals within the molecular junction.
acknowledgement: We thank Prof. Volker Blum for useful discussions. We thank the Department
of Energy Office of Basic Energy Science (DE-SC0019017) and the National Science
Foundation (NSF-DMR 2241180) for supporting this research. This work was supported
in part by the Institute of Science and Technology Austria.
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Wanzhuo
full_name: Shi, Wanzhuo
id: a3010425-87c8-11f0-8106-bec32bea74da
last_name: Shi
- first_name: Mengjiao
full_name: Wang, Mengjiao
last_name: Wang
- first_name: Latha
full_name: Venkataraman, Latha
id: 9ebb78a5-cc0d-11ee-8322-fae086a32caf
last_name: Venkataraman
orcid: 0000-0002-6957-6089
- first_name: John D.
full_name: Tovar, John D.
last_name: Tovar
citation:
ama: Shi W, Wang M, Venkataraman L, Tovar JD. Single-molecule conductance through
hybrid radially and linearly π-conjugated macromolecules reveals an unusual intramolecular
π-interaction. Nano Letters. 2025;25(31):12101-12106. doi:10.1021/acs.nanolett.5c03693
apa: Shi, W., Wang, M., Venkataraman, L., & Tovar, J. D. (2025). Single-molecule
conductance through hybrid radially and linearly π-conjugated macromolecules reveals
an unusual intramolecular π-interaction. Nano Letters. American Chemical
Society. https://doi.org/10.1021/acs.nanolett.5c03693
chicago: Shi, Wanzhuo, Mengjiao Wang, Latha Venkataraman, and John D. Tovar. “Single-Molecule
Conductance through Hybrid Radially and Linearly π-Conjugated Macromolecules Reveals
an Unusual Intramolecular π-Interaction.” Nano Letters. American Chemical
Society, 2025. https://doi.org/10.1021/acs.nanolett.5c03693.
ieee: W. Shi, M. Wang, L. Venkataraman, and J. D. Tovar, “Single-molecule conductance
through hybrid radially and linearly π-conjugated macromolecules reveals an unusual
intramolecular π-interaction,” Nano Letters, vol. 25, no. 31. American
Chemical Society, pp. 12101–12106, 2025.
ista: Shi W, Wang M, Venkataraman L, Tovar JD. 2025. Single-molecule conductance
through hybrid radially and linearly π-conjugated macromolecules reveals an unusual
intramolecular π-interaction. Nano Letters. 25(31), 12101–12106.
mla: Shi, Wanzhuo, et al. “Single-Molecule Conductance through Hybrid Radially and
Linearly π-Conjugated Macromolecules Reveals an Unusual Intramolecular π-Interaction.”
Nano Letters, vol. 25, no. 31, American Chemical Society, 2025, pp. 12101–06,
doi:10.1021/acs.nanolett.5c03693.
short: W. Shi, M. Wang, L. Venkataraman, J.D. Tovar, Nano Letters 25 (2025) 12101–12106.
corr_author: '1'
date_created: 2025-08-24T22:01:30Z
date_published: 2025-07-24T00:00:00Z
date_updated: 2025-09-30T14:23:39Z
day: '24'
ddc:
- '540'
department:
- _id: LaVe
doi: 10.1021/acs.nanolett.5c03693
external_id:
isi:
- '001537145800001'
pmid:
- '40707400'
file:
- access_level: open_access
checksum: bfc167d8904c0c47c3de2a8d0ec699d5
content_type: application/pdf
creator: dernst
date_created: 2025-09-02T06:50:11Z
date_updated: 2025-09-02T06:50:11Z
file_id: '20269'
file_name: 2025_NanoLetters_Shi.pdf
file_size: 3212706
relation: main_file
success: 1
file_date_updated: 2025-09-02T06:50:11Z
has_accepted_license: '1'
intvolume: ' 25'
isi: 1
issue: '31'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 12101-12106
pmid: 1
publication: Nano Letters
publication_identifier:
eissn:
- 1530-6992
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Single-molecule conductance through hybrid radially and linearly π-conjugated
macromolecules reveals an unusual intramolecular π-interaction
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type: journal_article
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volume: 25
year: '2025'
...
---
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OA_type: hybrid
_id: '20222'
abstract:
- lang: eng
text: Let X be a smooth projective hypersurface defined over Q. We provide new bounds
for rational points of bounded height on X. In particular, we show that if X is
a smooth projective hypersurface in Pn with n 4 and degree d 50, then the set
of rational points on X of height bounded by B have cardinality On,d,ε (Bn−2+ε
). If X is smooth and has degree d 6, we improve the dimension growth conjecture
bound. We achieve an analogue result for affine hypersurfaces whose projective
closure is smooth.
acknowledgement: "While working on this paper, the author was supported by the European
Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie
Grant Agreement No. 101034413. The author is very grateful to Tim Browning for suggesting
the problem and for many useful discussions. We thank the anonymous referees for
their many helpful comments, which improved the exposition of the paper. We are
also grateful to Gal Binyamini for their interest in this work and for drawing our
attention to the aforementioned paper [1].\r\nWe shared an early version of this
paper with Per Salberger, who mentioned that he announced a new bound for smooth
threefolds in P4 during a talk in 2019 (see [7] for the abstract). This result has
not been published."
article_number: rnaf249
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Matteo
full_name: Verzobio, Matteo
id: 7aa8f170-131e-11ed-88e1-a9efd01027cb
last_name: Verzobio
orcid: 0000-0002-0854-0306
citation:
ama: Verzobio M. Counting rational points on smooth hypersurfaces with high degree.
International Mathematics Research Notices. 2025;2025(16). doi:10.1093/imrn/rnaf249
apa: Verzobio, M. (2025). Counting rational points on smooth hypersurfaces with
high degree. International Mathematics Research Notices. Oxford University
Press. https://doi.org/10.1093/imrn/rnaf249
chicago: Verzobio, Matteo. “Counting Rational Points on Smooth Hypersurfaces with
High Degree.” International Mathematics Research Notices. Oxford University
Press, 2025. https://doi.org/10.1093/imrn/rnaf249.
ieee: M. Verzobio, “Counting rational points on smooth hypersurfaces with high degree,”
International Mathematics Research Notices, vol. 2025, no. 16. Oxford University
Press, 2025.
ista: Verzobio M. 2025. Counting rational points on smooth hypersurfaces with high
degree. International Mathematics Research Notices. 2025(16), rnaf249.
mla: Verzobio, Matteo. “Counting Rational Points on Smooth Hypersurfaces with High
Degree.” International Mathematics Research Notices, vol. 2025, no. 16,
rnaf249, Oxford University Press, 2025, doi:10.1093/imrn/rnaf249.
short: M. Verzobio, International Mathematics Research Notices 2025 (2025).
corr_author: '1'
date_created: 2025-08-24T22:01:31Z
date_published: 2025-08-01T00:00:00Z
date_updated: 2025-09-30T14:26:34Z
day: '01'
ddc:
- '510'
department:
- _id: TiBr
doi: 10.1093/imrn/rnaf249
ec_funded: 1
external_id:
arxiv:
- '2503.19451'
isi:
- '001549126000001'
file:
- access_level: open_access
checksum: 482ae2be98841ee446cf2bdfcd79f86f
content_type: application/pdf
creator: dernst
date_created: 2025-09-02T07:55:05Z
date_updated: 2025-09-02T07:55:05Z
file_id: '20275'
file_name: 2025_IMRN_Verzobio.pdf
file_size: 540263
relation: main_file
success: 1
file_date_updated: 2025-09-02T07:55:05Z
has_accepted_license: '1'
intvolume: ' 2025'
isi: 1
issue: '16'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
call_identifier: H2020
grant_number: '101034413'
name: 'IST-BRIDGE: International postdoctoral program'
publication: International Mathematics Research Notices
publication_identifier:
eissn:
- 1687-0247
issn:
- 1073-7928
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Counting rational points on smooth hypersurfaces with high degree
tmp:
image: /images/cc_by_nc_nd.png
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(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 2025
year: '2025'
...