---
_id: '17597'
abstract:
- lang: eng
  text: Deep Neural Networks (DNNs) are powerful algorithms that have been proven
    capable of extracting non-Gaussian information from weak lensing (WL) data sets.
    Understanding which features in the data determine the output of these nested,
    non-linear algorithms is an important but challenging task. We analyze a DNN that
    has been found in previous work to accurately recover cosmological parameters
    in simulated maps of the WL convergence (κ). We derive constraints on the cosmological
    parameter pair (Ωm,σ8) from a combination of three commonly used WL statistics
    (power spectrum, lensing peaks, and Minkowski functionals), using ray-traced simulated
    κ maps. We show that the network can improve the inferred parameter constraints
    relative to this combination by 20% even in the presence of realistic levels of
    shape noise. We apply a series of well established saliency methods to interpret
    the DNN and find that the most relevant pixels are those with extreme κ values.
    For noiseless maps, regions with negative κ account for 86−69% of the attribution
    of the DNN output, defined as the square of the saliency in input space. In the
    presence of shape nose, the attribution concentrates in high convergence regions,
    with 36−68% of the attribution in regions with κ>3σκ.
article_number: '123506'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: José Manuel Zorrilla
  full_name: Matilla, José Manuel Zorrilla
  last_name: Matilla
- first_name: Manasi
  full_name: Sharma, Manasi
  last_name: Sharma
- first_name: Daniel
  full_name: Hsu, Daniel
  last_name: Hsu
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
citation:
  ama: Matilla JMZ, Sharma M, Hsu D, Haiman Z. Interpreting deep learning models for
    weak lensing. <i>Physical Review D</i>. 2020;102(12). doi:<a href="https://doi.org/10.1103/physrevd.102.123506">10.1103/physrevd.102.123506</a>
  apa: Matilla, J. M. Z., Sharma, M., Hsu, D., &#38; Haiman, Z. (2020). Interpreting
    deep learning models for weak lensing. <i>Physical Review D</i>. American Physical
    Society. <a href="https://doi.org/10.1103/physrevd.102.123506">https://doi.org/10.1103/physrevd.102.123506</a>
  chicago: Matilla, José Manuel Zorrilla, Manasi Sharma, Daniel Hsu, and Zoltán Haiman.
    “Interpreting Deep Learning Models for Weak Lensing.” <i>Physical Review D</i>.
    American Physical Society, 2020. <a href="https://doi.org/10.1103/physrevd.102.123506">https://doi.org/10.1103/physrevd.102.123506</a>.
  ieee: J. M. Z. Matilla, M. Sharma, D. Hsu, and Z. Haiman, “Interpreting deep learning
    models for weak lensing,” <i>Physical Review D</i>, vol. 102, no. 12. American
    Physical Society, 2020.
  ista: Matilla JMZ, Sharma M, Hsu D, Haiman Z. 2020. Interpreting deep learning models
    for weak lensing. Physical Review D. 102(12), 123506.
  mla: Matilla, José Manuel Zorrilla, et al. “Interpreting Deep Learning Models for
    Weak Lensing.” <i>Physical Review D</i>, vol. 102, no. 12, 123506, American Physical
    Society, 2020, doi:<a href="https://doi.org/10.1103/physrevd.102.123506">10.1103/physrevd.102.123506</a>.
  short: J.M.Z. Matilla, M. Sharma, D. Hsu, Z. Haiman, Physical Review D 102 (2020).
date_created: 2024-09-05T12:44:45Z
date_published: 2020-07-09T00:00:00Z
date_updated: 2024-09-23T13:04:36Z
day: '09'
doi: 10.1103/physrevd.102.123506
extern: '1'
external_id:
  arxiv:
  - '2007.06529'
intvolume: '       102'
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: ' https://doi.org/10.48550/arXiv.2007.06529'
month: '07'
oa: 1
oa_version: Preprint
publication: Physical Review D
publication_identifier:
  issn:
  - 2470-0010
  - 2470-0029
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Interpreting deep learning models for weak lensing
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 102
year: '2020'
...
---
_id: '17600'
abstract:
- lang: eng
  text: The quest for binary and dual supermassive black holes (SMBHs) at the dawn
    of the multi-messenger era is compelling. Detecting dual active galactic nuclei
    (AGN) – active SMBHs at projected separations larger than several parsecs – and
    binary AGN – probing the scale where SMBHs are bound in a Keplerian binary – is
    an observational challenge. The study of AGN pairs (either dual or binary) also
    represents an overarching theoretical problem in cosmology and astrophysics. The
    AGN triggering calls for detailed knowledge of the hydrodynamical conditions of
    gas in the imminent surroundings of the SMBHs and, at the same time, their duality
    calls for detailed knowledge on how galaxies assemble through major and minor
    mergers and grow fed by matter along the filaments of the cosmic web. This review
    describes the techniques used across the electromagnetic spectrum to detect dual
    and binary AGN candidates and proposes new avenues for their search. The current
    observational status is compared with the state-of-the-art numerical simulations
    and models for formation of dual and binary AGN. Binary SMBHs are among the loudest
    sources of gravitational waves (GWs) in the Universe. The search for a background
    of GWs at nHz frequencies from inspiralling SMBHs at low redshifts, and the direct
    detection of signals from their coalescence by the Laser Interferometer Space
    Antenna in the next decade, make this a theme of major interest for multi-messenger
    astrophysics. This review discusses the future facilities and observational strategies
    that are likely to significantly advance this fascinating field.
article_number: '101525'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Alessandra
  full_name: De Rosa, Alessandra
  last_name: De Rosa
- first_name: Cristian
  full_name: Vignali, Cristian
  last_name: Vignali
- first_name: Tamara
  full_name: Bogdanović, Tamara
  last_name: Bogdanović
- first_name: Pedro R.
  full_name: Capelo, Pedro R.
  last_name: Capelo
- first_name: Maria
  full_name: Charisi, Maria
  last_name: Charisi
- first_name: Massimo
  full_name: Dotti, Massimo
  last_name: Dotti
- first_name: Bernd
  full_name: Husemann, Bernd
  last_name: Husemann
- first_name: Elisabeta
  full_name: Lusso, Elisabeta
  last_name: Lusso
- first_name: Lucio
  full_name: Mayer, Lucio
  last_name: Mayer
- first_name: Zsolt
  full_name: Paragi, Zsolt
  last_name: Paragi
- first_name: Jessie
  full_name: Runnoe, Jessie
  last_name: Runnoe
- first_name: Alberto
  full_name: Sesana, Alberto
  last_name: Sesana
- first_name: Lisa
  full_name: Steinborn, Lisa
  last_name: Steinborn
- first_name: Stefano
  full_name: Bianchi, Stefano
  last_name: Bianchi
- first_name: Monica
  full_name: Colpi, Monica
  last_name: Colpi
- first_name: Luciano
  full_name: del Valle, Luciano
  last_name: del Valle
- first_name: Sándor
  full_name: Frey, Sándor
  last_name: Frey
- first_name: Krisztina É.
  full_name: Gabányi, Krisztina É.
  last_name: Gabányi
- first_name: Margherita
  full_name: Giustini, Margherita
  last_name: Giustini
- first_name: Matteo
  full_name: Guainazzi, Matteo
  last_name: Guainazzi
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
- first_name: Noelia
  full_name: Herrera Ruiz, Noelia
  last_name: Herrera Ruiz
- first_name: Rubén
  full_name: Herrero-Illana, Rubén
  last_name: Herrero-Illana
- first_name: Kazushi
  full_name: Iwasawa, Kazushi
  last_name: Iwasawa
- first_name: S.
  full_name: Komossa, S.
  last_name: Komossa
- first_name: Davide
  full_name: Lena, Davide
  last_name: Lena
- first_name: Nora
  full_name: Loiseau, Nora
  last_name: Loiseau
- first_name: Miguel
  full_name: Perez-Torres, Miguel
  last_name: Perez-Torres
- first_name: Enrico
  full_name: Piconcelli, Enrico
  last_name: Piconcelli
- first_name: Marta
  full_name: Volonteri, Marta
  last_name: Volonteri
citation:
  ama: 'De Rosa A, Vignali C, Bogdanović T, et al. The quest for dual and binary supermassive
    black holes: A multi-messenger view. <i>New Astronomy Reviews</i>. 2020;86. doi:<a
    href="https://doi.org/10.1016/j.newar.2020.101525">10.1016/j.newar.2020.101525</a>'
  apa: 'De Rosa, A., Vignali, C., Bogdanović, T., Capelo, P. R., Charisi, M., Dotti,
    M., … Volonteri, M. (2020). The quest for dual and binary supermassive black holes:
    A multi-messenger view. <i>New Astronomy Reviews</i>. Elsevier BV. <a href="https://doi.org/10.1016/j.newar.2020.101525">https://doi.org/10.1016/j.newar.2020.101525</a>'
  chicago: 'De Rosa, Alessandra, Cristian Vignali, Tamara Bogdanović, Pedro R. Capelo,
    Maria Charisi, Massimo Dotti, Bernd Husemann, et al. “The Quest for Dual and Binary
    Supermassive Black Holes: A Multi-Messenger View.” <i>New Astronomy Reviews</i>.
    Elsevier BV, 2020. <a href="https://doi.org/10.1016/j.newar.2020.101525">https://doi.org/10.1016/j.newar.2020.101525</a>.'
  ieee: 'A. De Rosa <i>et al.</i>, “The quest for dual and binary supermassive black
    holes: A multi-messenger view,” <i>New Astronomy Reviews</i>, vol. 86. Elsevier
    BV, 2020.'
  ista: 'De Rosa A, Vignali C, Bogdanović T, Capelo PR, Charisi M, Dotti M, Husemann
    B, Lusso E, Mayer L, Paragi Z, Runnoe J, Sesana A, Steinborn L, Bianchi S, Colpi
    M, del Valle L, Frey S, Gabányi KÉ, Giustini M, Guainazzi M, Haiman Z, Herrera
    Ruiz N, Herrero-Illana R, Iwasawa K, Komossa S, Lena D, Loiseau N, Perez-Torres
    M, Piconcelli E, Volonteri M. 2020. The quest for dual and binary supermassive
    black holes: A multi-messenger view. New Astronomy Reviews. 86, 101525.'
  mla: 'De Rosa, Alessandra, et al. “The Quest for Dual and Binary Supermassive Black
    Holes: A Multi-Messenger View.” <i>New Astronomy Reviews</i>, vol. 86, 101525,
    Elsevier BV, 2020, doi:<a href="https://doi.org/10.1016/j.newar.2020.101525">10.1016/j.newar.2020.101525</a>.'
  short: A. De Rosa, C. Vignali, T. Bogdanović, P.R. Capelo, M. Charisi, M. Dotti,
    B. Husemann, E. Lusso, L. Mayer, Z. Paragi, J. Runnoe, A. Sesana, L. Steinborn,
    S. Bianchi, M. Colpi, L. del Valle, S. Frey, K.É. Gabányi, M. Giustini, M. Guainazzi,
    Z. Haiman, N. Herrera Ruiz, R. Herrero-Illana, K. Iwasawa, S. Komossa, D. Lena,
    N. Loiseau, M. Perez-Torres, E. Piconcelli, M. Volonteri, New Astronomy Reviews
    86 (2020).
date_created: 2024-09-05T13:07:32Z
date_published: 2020-01-17T00:00:00Z
date_updated: 2024-09-23T13:34:58Z
day: '17'
doi: 10.1016/j.newar.2020.101525
extern: '1'
external_id:
  arxiv:
  - '2001.06293'
intvolume: '        86'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: ' https://doi.org/10.48550/arXiv.2001.06293'
month: '01'
oa: 1
oa_version: Preprint
publication: New Astronomy Reviews
publication_identifier:
  issn:
  - 1387-6473
publication_status: published
publisher: Elsevier BV
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The quest for dual and binary supermassive black holes: A multi-messenger
  view'
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 86
year: '2020'
...
---
_id: '17601'
abstract:
- lang: eng
  text: Using numerical hydrodynamics calculations and a novel method for densely
    sampling parameter space, we measure the accretion and torque on a binary system
    from a circumbinary disk. In agreement with some earlier studies, we find that
    the net torque on the binary is positive for mass ratios close to unity, and that
    accretion always drives the binary toward equal mass. Accretion variability depends
    sensitively on the numerical sink prescription, but the torque and relative accretion
    onto each component do not depend on the sink timescale. Positive torque and highly
    variable accretion occurs only for mass ratios greater than around 0.05. This
    means that for mass ratios below 0.05, the binary would migrate inward until the
    secondary accreted sufficient mass, after which it would execute a U-turn and
    migrate outward. We explore a range of viscosities, from α = 0.03 to α = 0.15,
    and find that this outward torque is proportional to the viscous torque, so that
    torque per unit accreted mass is independent of α. Dependence of accretion and
    torque on mass ratio is explored in detail, densely sampling mass ratios between
    0.01 and unity. For mass ratio q > 0.2, accretion variability is found to exhibit
    a distinct sawtooth pattern, typically with a five-orbit cycle that provides a
    smoking gun prediction for variable quasars observed over long periods, as a potential
    means to confirm the presence of a binary.
article_number: '25'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Paul C.
  full_name: Duffell, Paul C.
  last_name: Duffell
- first_name: Daniel
  full_name: D’Orazio, Daniel
  last_name: D’Orazio
- first_name: Andrea
  full_name: Derdzinski, Andrea
  last_name: Derdzinski
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
- first_name: Andrew
  full_name: MacFadyen, Andrew
  last_name: MacFadyen
- first_name: Anna L.
  full_name: Rosen, Anna L.
  last_name: Rosen
- first_name: Jonathan
  full_name: Zrake, Jonathan
  last_name: Zrake
citation:
  ama: 'Duffell PC, D’Orazio D, Derdzinski A, et al. Circumbinary disks: Accretion
    and torque as a function of mass ratio and disk viscosity. <i>The Astrophysical
    Journal</i>. 2020;901(1). doi:<a href="https://doi.org/10.3847/1538-4357/abab95">10.3847/1538-4357/abab95</a>'
  apa: 'Duffell, P. C., D’Orazio, D., Derdzinski, A., Haiman, Z., MacFadyen, A., Rosen,
    A. L., &#38; Zrake, J. (2020). Circumbinary disks: Accretion and torque as a function
    of mass ratio and disk viscosity. <i>The Astrophysical Journal</i>. American Astronomical
    Society. <a href="https://doi.org/10.3847/1538-4357/abab95">https://doi.org/10.3847/1538-4357/abab95</a>'
  chicago: 'Duffell, Paul C., Daniel D’Orazio, Andrea Derdzinski, Zoltán Haiman, Andrew
    MacFadyen, Anna L. Rosen, and Jonathan Zrake. “Circumbinary Disks: Accretion and
    Torque as a Function of Mass Ratio and Disk Viscosity.” <i>The Astrophysical Journal</i>.
    American Astronomical Society, 2020. <a href="https://doi.org/10.3847/1538-4357/abab95">https://doi.org/10.3847/1538-4357/abab95</a>.'
  ieee: 'P. C. Duffell <i>et al.</i>, “Circumbinary disks: Accretion and torque as
    a function of mass ratio and disk viscosity,” <i>The Astrophysical Journal</i>,
    vol. 901, no. 1. American Astronomical Society, 2020.'
  ista: 'Duffell PC, D’Orazio D, Derdzinski A, Haiman Z, MacFadyen A, Rosen AL, Zrake
    J. 2020. Circumbinary disks: Accretion and torque as a function of mass ratio
    and disk viscosity. The Astrophysical Journal. 901(1), 25.'
  mla: 'Duffell, Paul C., et al. “Circumbinary Disks: Accretion and Torque as a Function
    of Mass Ratio and Disk Viscosity.” <i>The Astrophysical Journal</i>, vol. 901,
    no. 1, 25, American Astronomical Society, 2020, doi:<a href="https://doi.org/10.3847/1538-4357/abab95">10.3847/1538-4357/abab95</a>.'
  short: P.C. Duffell, D. D’Orazio, A. Derdzinski, Z. Haiman, A. MacFadyen, A.L. Rosen,
    J. Zrake, The Astrophysical Journal 901 (2020).
date_created: 2024-09-05T13:08:20Z
date_published: 2020-09-17T00:00:00Z
date_updated: 2024-09-23T13:39:03Z
day: '17'
doi: 10.3847/1538-4357/abab95
extern: '1'
external_id:
  arxiv:
  - '1911.05506'
intvolume: '       901'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: ' https://doi.org/10.48550/arXiv.1911.05506'
month: '09'
oa: 1
oa_version: Preprint
publication: The Astrophysical Journal
publication_identifier:
  issn:
  - 0004-637X
  - 1538-4357
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Circumbinary disks: Accretion and torque as a function of mass ratio and disk
  viscosity'
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 901
year: '2020'
...
---
_id: '17604'
abstract:
- lang: eng
  text: 'Numerical studies of gas accretion onto supermassive black hole binaries
    (SMBHBs) have generally been limited to conditions where the circumbinary disk
    (CBD) is 10-100 times thicker than expected for disks in active galactic nuclei
    (AGN). This discrepancy arises from technical limitations, and also from publication
    bias toward replicating fiducial numerical models. Here we present the first systematic
    study of how the binary''s orbital evolution varies with disk scale height. We
    report three key results: (1) Binary orbital evolution switches from outspiralling
    for warm disks (aspect ratio ~0.1), to inspiralling for more realistic cooler,
    thinner disks at a critical aspect ratio ~0.04, corresponding to orbital Mach
    number ~25. (2) The net torque on the binary arises from a competition between
    positive torque from gas orbiting close to the black holes, and negative torque
    from the inner edge of the CBD, which is denser for thinner disks. This leads
    to increasingly negative net torques on the binary for increasingly thin disks.
    (3) The accretion rate is modestly suppressed with increasing Mach number. We
    discuss how our results may influence modeling of the nano-Hz gravitational wave
    background, as well as estimates of the LISA merger event rate.'
article_number: '43'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Christopher
  full_name: Tiede, Christopher
  last_name: Tiede
- first_name: Jonathan
  full_name: Zrake, Jonathan
  last_name: Zrake
- first_name: Andrew
  full_name: MacFadyen, Andrew
  last_name: MacFadyen
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
citation:
  ama: Tiede C, Zrake J, MacFadyen A, Haiman Z. Gas-driven inspiral of binaries in
    thin accretion disks. <i>The Astrophysical Journal</i>. 2020;900(1). doi:<a href="https://doi.org/10.3847/1538-4357/aba432">10.3847/1538-4357/aba432</a>
  apa: Tiede, C., Zrake, J., MacFadyen, A., &#38; Haiman, Z. (2020). Gas-driven inspiral
    of binaries in thin accretion disks. <i>The Astrophysical Journal</i>. American
    Astronomical Society. <a href="https://doi.org/10.3847/1538-4357/aba432">https://doi.org/10.3847/1538-4357/aba432</a>
  chicago: Tiede, Christopher, Jonathan Zrake, Andrew MacFadyen, and Zoltán Haiman.
    “Gas-Driven Inspiral of Binaries in Thin Accretion Disks.” <i>The Astrophysical
    Journal</i>. American Astronomical Society, 2020. <a href="https://doi.org/10.3847/1538-4357/aba432">https://doi.org/10.3847/1538-4357/aba432</a>.
  ieee: C. Tiede, J. Zrake, A. MacFadyen, and Z. Haiman, “Gas-driven inspiral of binaries
    in thin accretion disks,” <i>The Astrophysical Journal</i>, vol. 900, no. 1. American
    Astronomical Society, 2020.
  ista: Tiede C, Zrake J, MacFadyen A, Haiman Z. 2020. Gas-driven inspiral of binaries
    in thin accretion disks. The Astrophysical Journal. 900(1), 43.
  mla: Tiede, Christopher, et al. “Gas-Driven Inspiral of Binaries in Thin Accretion
    Disks.” <i>The Astrophysical Journal</i>, vol. 900, no. 1, 43, American Astronomical
    Society, 2020, doi:<a href="https://doi.org/10.3847/1538-4357/aba432">10.3847/1538-4357/aba432</a>.
  short: C. Tiede, J. Zrake, A. MacFadyen, Z. Haiman, The Astrophysical Journal 900
    (2020).
date_created: 2024-09-05T13:12:20Z
date_published: 2020-08-28T00:00:00Z
date_updated: 2024-09-23T13:59:30Z
day: '28'
doi: 10.3847/1538-4357/aba432
extern: '1'
external_id:
  arxiv:
  - '2005.09555'
intvolume: '       900'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: ' https://doi.org/10.48550/arXiv.2005.09555'
month: '08'
oa: 1
oa_version: Preprint
publication: The Astrophysical Journal
publication_identifier:
  issn:
  - 0004-637X
  - 1538-4357
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Gas-driven inspiral of binaries in thin accretion disks
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 900
year: '2020'
...
---
_id: '17605'
abstract:
- lang: eng
  text: Despite the rapidly growing number of stellar-mass binary black hole mergers
    discovered through gravitational waves, the origin of these binaries is still
    not known. In galactic centers, black holes can be brought to each others' proximity
    by dynamical processes, resulting in mergers. It is also possible that black holes
    formed in previous mergers encounter new black holes, resulting in so-called hierarchical
    mergers. Hierarchical events carry signatures such as higher-than-usual black
    hole mass and spin. Here we show that the recently reported gravitational-wave
    candidate, GW170817A, could be the result of such a hierarchical merger. In particular,
    its chirp mass ∼40 M⊙ and effective spin of χeff ∼ 0.5 are the typically expected
    values from hierarchical mergers within the disks of active galactic nuclei. We
    find that the reconstructed parameters of GW170817A strongly favor a hierarchical
    merger origin over having been produced by an isolated binary origin (with an
    odds ratio of > 10^3).
article_number: L20
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: V.
  full_name: Gayathri, V.
  last_name: Gayathri
- first_name: I.
  full_name: Bartos, I.
  last_name: Bartos
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
- first_name: S.
  full_name: Klimenko, S.
  last_name: Klimenko
- first_name: B.
  full_name: Kocsis, B.
  last_name: Kocsis
- first_name: S.
  full_name: Márka, S.
  last_name: Márka
- first_name: Y.
  full_name: Yang, Y.
  last_name: Yang
citation:
  ama: Gayathri V, Bartos I, Haiman Z, et al. GW170817A as a hierarchical black hole
    merger. <i>The Astrophysical Journal Letters</i>. 2020;890(2). doi:<a href="https://doi.org/10.3847/2041-8213/ab745d">10.3847/2041-8213/ab745d</a>
  apa: Gayathri, V., Bartos, I., Haiman, Z., Klimenko, S., Kocsis, B., Márka, S.,
    &#38; Yang, Y. (2020). GW170817A as a hierarchical black hole merger. <i>The Astrophysical
    Journal Letters</i>. American Astronomical Society. <a href="https://doi.org/10.3847/2041-8213/ab745d">https://doi.org/10.3847/2041-8213/ab745d</a>
  chicago: Gayathri, V., I. Bartos, Zoltán Haiman, S. Klimenko, B. Kocsis, S. Márka,
    and Y. Yang. “GW170817A as a Hierarchical Black Hole Merger.” <i>The Astrophysical
    Journal Letters</i>. American Astronomical Society, 2020. <a href="https://doi.org/10.3847/2041-8213/ab745d">https://doi.org/10.3847/2041-8213/ab745d</a>.
  ieee: V. Gayathri <i>et al.</i>, “GW170817A as a hierarchical black hole merger,”
    <i>The Astrophysical Journal Letters</i>, vol. 890, no. 2. American Astronomical
    Society, 2020.
  ista: Gayathri V, Bartos I, Haiman Z, Klimenko S, Kocsis B, Márka S, Yang Y. 2020.
    GW170817A as a hierarchical black hole merger. The Astrophysical Journal Letters.
    890(2), L20.
  mla: Gayathri, V., et al. “GW170817A as a Hierarchical Black Hole Merger.” <i>The
    Astrophysical Journal Letters</i>, vol. 890, no. 2, L20, American Astronomical
    Society, 2020, doi:<a href="https://doi.org/10.3847/2041-8213/ab745d">10.3847/2041-8213/ab745d</a>.
  short: V. Gayathri, I. Bartos, Z. Haiman, S. Klimenko, B. Kocsis, S. Márka, Y. Yang,
    The Astrophysical Journal Letters 890 (2020).
date_created: 2024-09-05T13:13:33Z
date_published: 2020-02-18T00:00:00Z
date_updated: 2024-09-23T14:04:29Z
day: '18'
doi: 10.3847/2041-8213/ab745d
extern: '1'
external_id:
  arxiv:
  - '1911.11142'
intvolume: '       890'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: ' https://doi.org/10.48550/arXiv.1911.11142'
month: '02'
oa: 1
oa_version: Preprint
publication: The Astrophysical Journal Letters
publication_identifier:
  issn:
  - 2041-8205
  - 2041-8213
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: GW170817A as a hierarchical black hole merger
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 890
year: '2020'
...
---
_id: '17607'
abstract:
- lang: eng
  text: The heaviest neutron stars and lightest black holes expected to be produced
    by stellar evolution leave the mass-range 2.2 M⊙≲m≲5 M⊙ largely unpopulated. Objects
    found in this so-called lower mass gap likely originate from a distinct astrophysical
    process. Such an object, with mass 2.6 M⊙ was recently detected in the binary
    merger GW190814 through gravitational waves by LIGO/Virgo. Here we show that black
    holes in the mass gap are naturally assembled through mergers and accretion in
    AGN disks, and can subsequently participate in additional mergers. We compute
    the properties of AGN-assisted mergers involving neutron stars and black holes,
    accounting for accretion. We find that mergers in which one of the objects is
    in the lower mass gap represent up to 4% of AGN-assisted mergers detectable by
    LIGO/Virgo. The lighter object of GW190814, with mass 2.6 M⊙, could have grown
    in an AGN disk through accretion. We find that the unexpectedly high total mass
    of 3.4 M⊙ observed in the neutron star merger GW190425 may also be due to accretion
    in an AGN disk.
article_number: L34
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Y.
  full_name: Yang, Y.
  last_name: Yang
- first_name: V.
  full_name: Gayathri, V.
  last_name: Gayathri
- first_name: I.
  full_name: Bartos, I.
  last_name: Bartos
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
- first_name: M.
  full_name: Safarzadeh, M.
  last_name: Safarzadeh
- first_name: H.
  full_name: Tagawa, H.
  last_name: Tagawa
citation:
  ama: Yang Y, Gayathri V, Bartos I, Haiman Z, Safarzadeh M, Tagawa H. Black hole
    formation in the lower mass gap through mergers and accretion in AGN disks. <i>The
    Astrophysical Journal Letters</i>. 2020;901(2). doi:<a href="https://doi.org/10.3847/2041-8213/abb940">10.3847/2041-8213/abb940</a>
  apa: Yang, Y., Gayathri, V., Bartos, I., Haiman, Z., Safarzadeh, M., &#38; Tagawa,
    H. (2020). Black hole formation in the lower mass gap through mergers and accretion
    in AGN disks. <i>The Astrophysical Journal Letters</i>. American Astronomical
    Society. <a href="https://doi.org/10.3847/2041-8213/abb940">https://doi.org/10.3847/2041-8213/abb940</a>
  chicago: Yang, Y., V. Gayathri, I. Bartos, Zoltán Haiman, M. Safarzadeh, and H.
    Tagawa. “Black Hole Formation in the Lower Mass Gap through Mergers and Accretion
    in AGN Disks.” <i>The Astrophysical Journal Letters</i>. American Astronomical
    Society, 2020. <a href="https://doi.org/10.3847/2041-8213/abb940">https://doi.org/10.3847/2041-8213/abb940</a>.
  ieee: Y. Yang, V. Gayathri, I. Bartos, Z. Haiman, M. Safarzadeh, and H. Tagawa,
    “Black hole formation in the lower mass gap through mergers and accretion in AGN
    disks,” <i>The Astrophysical Journal Letters</i>, vol. 901, no. 2. American Astronomical
    Society, 2020.
  ista: Yang Y, Gayathri V, Bartos I, Haiman Z, Safarzadeh M, Tagawa H. 2020. Black
    hole formation in the lower mass gap through mergers and accretion in AGN disks.
    The Astrophysical Journal Letters. 901(2), L34.
  mla: Yang, Y., et al. “Black Hole Formation in the Lower Mass Gap through Mergers
    and Accretion in AGN Disks.” <i>The Astrophysical Journal Letters</i>, vol. 901,
    no. 2, L34, American Astronomical Society, 2020, doi:<a href="https://doi.org/10.3847/2041-8213/abb940">10.3847/2041-8213/abb940</a>.
  short: Y. Yang, V. Gayathri, I. Bartos, Z. Haiman, M. Safarzadeh, H. Tagawa, The
    Astrophysical Journal Letters 901 (2020).
date_created: 2024-09-05T13:15:59Z
date_published: 2020-10-01T00:00:00Z
date_updated: 2024-09-23T14:16:49Z
day: '01'
doi: 10.3847/2041-8213/abb940
extern: '1'
external_id:
  arxiv:
  - '2007.04781'
intvolume: '       901'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: ' https://doi.org/10.48550/arXiv.2007.04781'
month: '10'
oa: 1
oa_version: Preprint
publication: The Astrophysical Journal Letters
publication_identifier:
  issn:
  - 2041-8205
  - 2041-8213
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Black hole formation in the lower mass gap through mergers and accretion in
  AGN disks
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 901
year: '2020'
...
---
_id: '177'
abstract:
- lang: eng
  text: We develop a geometric version of the circle method and use it to compute
    the compactly supported cohomology of the space of rational curves through a point
    on a smooth affine hypersurface of sufficiently low degree.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Timothy D
  full_name: Browning, Timothy D
  id: 35827D50-F248-11E8-B48F-1D18A9856A87
  last_name: Browning
  orcid: 0000-0002-8314-0177
- first_name: Will
  full_name: Sawin, Will
  last_name: Sawin
citation:
  ama: Browning TD, Sawin W. A geometric version of the circle method. <i>Annals of
    Mathematics</i>. 2020;191(3):893-948. doi:<a href="https://doi.org/10.4007/annals.2020.191.3.4">10.4007/annals.2020.191.3.4</a>
  apa: Browning, T. D., &#38; Sawin, W. (2020). A geometric version of the circle
    method. <i>Annals of Mathematics</i>. Princeton University. <a href="https://doi.org/10.4007/annals.2020.191.3.4">https://doi.org/10.4007/annals.2020.191.3.4</a>
  chicago: Browning, Timothy D, and Will Sawin. “A Geometric Version of the Circle
    Method.” <i>Annals of Mathematics</i>. Princeton University, 2020. <a href="https://doi.org/10.4007/annals.2020.191.3.4">https://doi.org/10.4007/annals.2020.191.3.4</a>.
  ieee: T. D. Browning and W. Sawin, “A geometric version of the circle method,” <i>Annals
    of Mathematics</i>, vol. 191, no. 3. Princeton University, pp. 893–948, 2020.
  ista: Browning TD, Sawin W. 2020. A geometric version of the circle method. Annals
    of Mathematics. 191(3), 893–948.
  mla: Browning, Timothy D., and Will Sawin. “A Geometric Version of the Circle Method.”
    <i>Annals of Mathematics</i>, vol. 191, no. 3, Princeton University, 2020, pp.
    893–948, doi:<a href="https://doi.org/10.4007/annals.2020.191.3.4">10.4007/annals.2020.191.3.4</a>.
  short: T.D. Browning, W. Sawin, Annals of Mathematics 191 (2020) 893–948.
date_created: 2018-12-11T11:45:02Z
date_published: 2020-05-01T00:00:00Z
date_updated: 2024-10-21T06:02:25Z
day: '01'
department:
- _id: TiBr
doi: 10.4007/annals.2020.191.3.4
external_id:
  arxiv:
  - '1711.10451'
  isi:
  - '000526986300004'
intvolume: '       191'
isi: 1
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1711.10451
month: '05'
oa: 1
oa_version: Preprint
page: 893-948
publication: Annals of Mathematics
publication_status: published
publisher: Princeton University
publist_id: '7744'
quality_controlled: '1'
scopus_import: '1'
status: public
title: A geometric version of the circle method
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 191
year: '2020'
...
---
_id: '7665'
abstract:
- lang: eng
  text: Acute brain slice preparation is a powerful experimental model for investigating
    the characteristics of synaptic function in the brain. Although brain tissue is
    usually cut at ice-cold temperature (CT) to facilitate slicing and avoid neuronal
    damage, exposure to CT causes molecular and architectural changes of synapses.
    To address these issues, we investigated ultrastructural and electrophysiological
    features of synapses in mouse acute cerebellar slices prepared at ice-cold and
    physiological temperature (PT). In the slices prepared at CT, we found significant
    spine loss and reconstruction, synaptic vesicle rearrangement and decrease in
    synaptic proteins, all of which were not detected in slices prepared at PT. Consistent
    with these structural findings, slices prepared at PT showed higher release probability.
    Furthermore, preparation at PT allows electrophysiological recording immediately
    after slicing resulting in higher detectability of long-term depression (LTD)
    after motor learning compared with that at CT. These results indicate substantial
    advantages of the slice preparation at PT for investigating synaptic functions
    in different physiological conditions.
article_number: '63'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Kohgaku
  full_name: Eguchi, Kohgaku
  id: 2B7846DC-F248-11E8-B48F-1D18A9856A87
  last_name: Eguchi
  orcid: 0000-0002-6170-2546
- first_name: Philipp
  full_name: Velicky, Philipp
  id: 39BDC62C-F248-11E8-B48F-1D18A9856A87
  last_name: Velicky
  orcid: 0000-0002-2340-7431
- first_name: Elena
  full_name: Hollergschwandtner, Elena
  id: 3C054040-F248-11E8-B48F-1D18A9856A87
  last_name: Hollergschwandtner
- first_name: Makoto
  full_name: Itakura, Makoto
  last_name: Itakura
- first_name: Yugo
  full_name: Fukazawa, Yugo
  last_name: Fukazawa
- first_name: Johann G
  full_name: Danzl, Johann G
  id: 42EFD3B6-F248-11E8-B48F-1D18A9856A87
  last_name: Danzl
  orcid: 0000-0001-8559-3973
- first_name: Ryuichi
  full_name: Shigemoto, Ryuichi
  id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
  last_name: Shigemoto
  orcid: 0000-0001-8761-9444
citation:
  ama: Eguchi K, Velicky P, Saeckl E, et al. Advantages of acute brain slices prepared
    at physiological temperature in the characterization of synaptic functions. <i>Frontiers
    in Cellular Neuroscience</i>. 2020;14. doi:<a href="https://doi.org/10.3389/fncel.2020.00063">10.3389/fncel.2020.00063</a>
  apa: Eguchi, K., Velicky, P., Saeckl, E., Itakura, M., Fukazawa, Y., Danzl, J. G.,
    &#38; Shigemoto, R. (2020). Advantages of acute brain slices prepared at physiological
    temperature in the characterization of synaptic functions. <i>Frontiers in Cellular
    Neuroscience</i>. Frontiers Media. <a href="https://doi.org/10.3389/fncel.2020.00063">https://doi.org/10.3389/fncel.2020.00063</a>
  chicago: Eguchi, Kohgaku, Philipp Velicky, Elena Saeckl, Makoto Itakura, Yugo Fukazawa,
    Johann G Danzl, and Ryuichi Shigemoto. “Advantages of Acute Brain Slices Prepared
    at Physiological Temperature in the Characterization of Synaptic Functions.” <i>Frontiers
    in Cellular Neuroscience</i>. Frontiers Media, 2020. <a href="https://doi.org/10.3389/fncel.2020.00063">https://doi.org/10.3389/fncel.2020.00063</a>.
  ieee: K. Eguchi <i>et al.</i>, “Advantages of acute brain slices prepared at physiological
    temperature in the characterization of synaptic functions,” <i>Frontiers in Cellular
    Neuroscience</i>, vol. 14. Frontiers Media, 2020.
  ista: Eguchi K, Velicky P, Saeckl E, Itakura M, Fukazawa Y, Danzl JG, Shigemoto
    R. 2020. Advantages of acute brain slices prepared at physiological temperature
    in the characterization of synaptic functions. Frontiers in Cellular Neuroscience.
    14, 63.
  mla: Eguchi, Kohgaku, et al. “Advantages of Acute Brain Slices Prepared at Physiological
    Temperature in the Characterization of Synaptic Functions.” <i>Frontiers in Cellular
    Neuroscience</i>, vol. 14, 63, Frontiers Media, 2020, doi:<a href="https://doi.org/10.3389/fncel.2020.00063">10.3389/fncel.2020.00063</a>.
  short: K. Eguchi, P. Velicky, E. Saeckl, M. Itakura, Y. Fukazawa, J.G. Danzl, R.
    Shigemoto, Frontiers in Cellular Neuroscience 14 (2020).
corr_author: '1'
date_created: 2020-04-19T22:00:55Z
date_published: 2020-03-19T00:00:00Z
date_updated: 2025-06-12T07:16:39Z
day: '19'
ddc:
- '570'
department:
- _id: JoDa
- _id: RySh
doi: 10.3389/fncel.2020.00063
ec_funded: 1
external_id:
  isi:
  - '000525582200001'
  pmid:
  - '32265664'
file:
- access_level: open_access
  checksum: 1c145123c6f8dc3e2e4bd5a66a1ad60e
  content_type: application/pdf
  creator: dernst
  date_created: 2020-04-20T10:59:49Z
  date_updated: 2020-07-14T12:48:01Z
  file_id: '7668'
  file_name: 2020_FrontiersCellularNeurosc_Eguchi.pdf
  file_size: 9227283
  relation: main_file
file_date_updated: 2020-07-14T12:48:01Z
has_accepted_license: '1'
intvolume: '        14'
isi: 1
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 2659CC84-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '793482'
  name: 'Ultrastructural analysis of phosphoinositides in nerve terminals: distribution,
    dynamics and physiological roles in synaptic transmission'
- _id: 25CA28EA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '694539'
  name: 'In situ analysis of single channel subunit composition in neurons: physiological
    implication in synaptic plasticity and behaviour'
- _id: 265CB4D0-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I03600
  name: Optical control of synaptic function via adhesion molecules
- _id: B67AFEDC-15C9-11EA-A837-991A96BB2854
  name: IST Austria Open Access Fund
publication: Frontiers in Cellular Neuroscience
publication_identifier:
  issn:
  - 1662-5102
publication_status: published
publisher: Frontiers Media
quality_controlled: '1'
scopus_import: '1'
status: public
title: Advantages of acute brain slices prepared at physiological temperature in the
  characterization of synaptic functions
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 14
year: '2020'
...
---
_id: '7666'
abstract:
- lang: eng
  text: Generalizing the decomposition of a connected planar graph into a tree and
    a dual tree, we prove a combinatorial analog of the classic Helmholtz–Hodge decomposition
    of a smooth vector field. Specifically, we show that for every polyhedral complex,
    K, and every dimension, p, there is a partition of the set of p-cells into a maximal
    p-tree, a maximal p-cotree, and a collection of p-cells whose cardinality is the
    p-th reduced Betti number of K. Given an ordering of the p-cells, this tri-partition
    is unique, and it can be computed by a matrix reduction algorithm that also constructs
    canonical bases of cycle and boundary groups.
acknowledgement: This project has received funding from the European Research Council
  under the European Union’s Horizon 2020 research and innovation programme (Grant
  Agreement No. 78818 Alpha). It is also partially supported by the DFG Collaborative
  Research Center TRR 109, ‘Discretization in Geometry and Dynamics’, through Grant
  No. I02979-N35 of the Austrian Science Fund (FWF).
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
- first_name: Katharina
  full_name: Ölsböck, Katharina
  id: 4D4AA390-F248-11E8-B48F-1D18A9856A87
  last_name: Ölsböck
  orcid: 0000-0002-4672-8297
citation:
  ama: Edelsbrunner H, Ölsböck K. Tri-partitions and bases of an ordered complex.
    <i>Discrete and Computational Geometry</i>. 2020;64:759-775. doi:<a href="https://doi.org/10.1007/s00454-020-00188-x">10.1007/s00454-020-00188-x</a>
  apa: Edelsbrunner, H., &#38; Ölsböck, K. (2020). Tri-partitions and bases of an
    ordered complex. <i>Discrete and Computational Geometry</i>. Springer Nature.
    <a href="https://doi.org/10.1007/s00454-020-00188-x">https://doi.org/10.1007/s00454-020-00188-x</a>
  chicago: Edelsbrunner, Herbert, and Katharina Ölsböck. “Tri-Partitions and Bases
    of an Ordered Complex.” <i>Discrete and Computational Geometry</i>. Springer Nature,
    2020. <a href="https://doi.org/10.1007/s00454-020-00188-x">https://doi.org/10.1007/s00454-020-00188-x</a>.
  ieee: H. Edelsbrunner and K. Ölsböck, “Tri-partitions and bases of an ordered complex,”
    <i>Discrete and Computational Geometry</i>, vol. 64. Springer Nature, pp. 759–775,
    2020.
  ista: Edelsbrunner H, Ölsböck K. 2020. Tri-partitions and bases of an ordered complex.
    Discrete and Computational Geometry. 64, 759–775.
  mla: Edelsbrunner, Herbert, and Katharina Ölsböck. “Tri-Partitions and Bases of
    an Ordered Complex.” <i>Discrete and Computational Geometry</i>, vol. 64, Springer
    Nature, 2020, pp. 759–75, doi:<a href="https://doi.org/10.1007/s00454-020-00188-x">10.1007/s00454-020-00188-x</a>.
  short: H. Edelsbrunner, K. Ölsböck, Discrete and Computational Geometry 64 (2020)
    759–775.
corr_author: '1'
date_created: 2020-04-19T22:00:56Z
date_published: 2020-03-20T00:00:00Z
date_updated: 2025-04-14T07:48:36Z
day: '20'
ddc:
- '510'
department:
- _id: HeEd
doi: 10.1007/s00454-020-00188-x
ec_funded: 1
external_id:
  isi:
  - '000520918800001'
file:
- access_level: open_access
  checksum: f8cc96e497f00c38340b5dafe0cb91d7
  content_type: application/pdf
  creator: dernst
  date_created: 2020-11-20T13:22:21Z
  date_updated: 2020-11-20T13:22:21Z
  file_id: '8786'
  file_name: 2020_DiscreteCompGeo_Edelsbrunner.pdf
  file_size: 701673
  relation: main_file
  success: 1
file_date_updated: 2020-11-20T13:22:21Z
has_accepted_license: '1'
intvolume: '        64'
isi: 1
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 759-775
project:
- _id: B67AFEDC-15C9-11EA-A837-991A96BB2854
  name: IST Austria Open Access Fund
- _id: 266A2E9E-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '788183'
  name: Alpha Shape Theory Extended
- _id: 2561EBF4-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I02979-N35
  name: Persistence and stability of geometric complexes
publication: Discrete and Computational Geometry
publication_identifier:
  eissn:
  - '14320444'
  issn:
  - '01795376'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Tri-partitions and bases of an ordered complex
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 64
year: '2020'
...
---
_id: '7672'
abstract:
- lang: eng
  text: Large overpotentials upon discharge and charge of Li-O2 cells have motivated
    extensive research into heterogeneous solid electrocatalysts or non-carbon electrodes
    with the aim to improve rate capability, round-trip efficiency and cycle life.
    These features are equally governed by parasitic reactions, which are now recognized
    to be caused by the highly reactive singlet oxygen (1O2). However, the link between
    the presence of electrocatalysts and 1O2 formation in metal-O2 cells is unknown.
    Here, we show that, compared to pristine carbon black electrodes, a representative
    selection of electrocatalysts or non-carbon electrodes (noble metal, transition
    metal compounds) may both slightly reduce or severely increase the 1O2 formation.
    The individual reaction steps, where the surfaces impact the 1O2 yield are deciphered,
    showing that 1O2 yield from superoxide disproportionation as well as the decomposition
    of trace H2O2 are sensitive to catalysts. Transition metal compounds in general
    are prone to increase 1O2.
acknowledgement: S.A.F. thanks the International Society of Electrochemistry for awarding
  the Tajima Prize 2019 “in recognition of outstanding re- searches on Li-Air batteries
  by the use of a range of in-situ elec- trochemical methods to achieve comprehensive
  understanding of the reactions taking place at the oxygen electrode”. This article
  is dedicated to the special issue of Electrochmica Acta associated with the awarding
  conference. S.A.F. is indebted to and the Austrian Federal Ministry of Science,
  Research and Economy and the Austrian Research Promotion Agency (grant No. 845364
  ) and the European Research Council (ERC) under the European Union’s Horizon 2020
  research and innovation programme (grant agreement No 636069). The authors thank
  J. Schlegl for manufacturing instrumentation, M. Winkler of Acib GmbH and G. Strohmeier
  for help with HPLC measurements, S. Eder for cyclic voltammetry measurements, and
  C. Slugovc for discussions and continuous support. We thank S. Borisov for access
  and advice with fluorescence measurements. We thank EL-Cell GmbH, Hamburg, Germany
  for providing the PAT-Cell-Press electrochemical cell.
article_number: '137175'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Aleksej
  full_name: Samojlov, Aleksej
  last_name: Samojlov
- first_name: David
  full_name: Schuster, David
  last_name: Schuster
- first_name: Jürgen
  full_name: Kahr, Jürgen
  last_name: Kahr
- first_name: Stefan Alexander
  full_name: Freunberger, Stefan Alexander
  id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
  last_name: Freunberger
  orcid: 0000-0003-2902-5319
citation:
  ama: Samojlov A, Schuster D, Kahr J, Freunberger SA. Surface and catalyst driven
    singlet oxygen formation in Li-O2 cells. <i>Electrochimica Acta</i>. 2020;362(12).
    doi:<a href="https://doi.org/10.1016/j.electacta.2020.137175">10.1016/j.electacta.2020.137175</a>
  apa: Samojlov, A., Schuster, D., Kahr, J., &#38; Freunberger, S. A. (2020). Surface
    and catalyst driven singlet oxygen formation in Li-O2 cells. <i>Electrochimica
    Acta</i>. Elsevier. <a href="https://doi.org/10.1016/j.electacta.2020.137175">https://doi.org/10.1016/j.electacta.2020.137175</a>
  chicago: Samojlov, Aleksej, David Schuster, Jürgen Kahr, and Stefan Alexander Freunberger.
    “Surface and Catalyst Driven Singlet Oxygen Formation in Li-O2 Cells.” <i>Electrochimica
    Acta</i>. Elsevier, 2020. <a href="https://doi.org/10.1016/j.electacta.2020.137175">https://doi.org/10.1016/j.electacta.2020.137175</a>.
  ieee: A. Samojlov, D. Schuster, J. Kahr, and S. A. Freunberger, “Surface and catalyst
    driven singlet oxygen formation in Li-O2 cells,” <i>Electrochimica Acta</i>, vol.
    362, no. 12. Elsevier, 2020.
  ista: Samojlov A, Schuster D, Kahr J, Freunberger SA. 2020. Surface and catalyst
    driven singlet oxygen formation in Li-O2 cells. Electrochimica Acta. 362(12),
    137175.
  mla: Samojlov, Aleksej, et al. “Surface and Catalyst Driven Singlet Oxygen Formation
    in Li-O2 Cells.” <i>Electrochimica Acta</i>, vol. 362, no. 12, 137175, Elsevier,
    2020, doi:<a href="https://doi.org/10.1016/j.electacta.2020.137175">10.1016/j.electacta.2020.137175</a>.
  short: A. Samojlov, D. Schuster, J. Kahr, S.A. Freunberger, Electrochimica Acta
    362 (2020).
corr_author: '1'
date_created: 2020-04-20T19:29:31Z
date_published: 2020-12-01T00:00:00Z
date_updated: 2024-10-09T20:59:27Z
day: '01'
ddc:
- '540'
department:
- _id: StFr
doi: 10.1016/j.electacta.2020.137175
external_id:
  isi:
  - '000582869700060'
file:
- access_level: open_access
  checksum: 1ab1aa2024d431e2a089ea336bc08298
  content_type: application/pdf
  creator: dernst
  date_created: 2020-10-01T13:20:45Z
  date_updated: 2020-10-01T13:20:45Z
  file_id: '8593'
  file_name: 2020_ElectrochimicaActa_Samojlov.pdf
  file_size: 1404030
  relation: main_file
  success: 1
file_date_updated: 2020-10-01T13:20:45Z
has_accepted_license: '1'
intvolume: '       362'
isi: 1
issue: '12'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
publication: Electrochimica Acta
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Surface and catalyst driven singlet oxygen formation in Li-O2 cells
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 362
year: '2020'
...
---
_id: '7683'
abstract:
- lang: eng
  text: For any free oriented Borel–Moore homology theory A, we construct an associative
    product on the A-theory of the stack of Higgs torsion sheaves over a projective
    curve C. We show that the resulting algebra AHa0C admits a natural shuffle presentation,
    and prove it is faithful when A is replaced with usual Borel–Moore homology groups.
    We also introduce moduli spaces of stable triples, heavily inspired by Nakajima
    quiver varieties, whose A-theory admits an AHa0C-action. These triples can be
    interpreted as certain sheaves on PC(ωC⊕OC). In particular, we obtain an action
    of AHa0C on the cohomology of Hilbert schemes of points on T∗C.
article_number: '30'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Sasha
  full_name: Minets, Sasha
  id: 3E7C5304-F248-11E8-B48F-1D18A9856A87
  last_name: Minets
  orcid: 0000-0003-3883-1806
citation:
  ama: Minets S. Cohomological Hall algebras for Higgs torsion sheaves, moduli of
    triples and sheaves on surfaces. <i>Selecta Mathematica, New Series</i>. 2020;26(2).
    doi:<a href="https://doi.org/10.1007/s00029-020-00553-x">10.1007/s00029-020-00553-x</a>
  apa: Minets, S. (2020). Cohomological Hall algebras for Higgs torsion sheaves, moduli
    of triples and sheaves on surfaces. <i>Selecta Mathematica, New Series</i>. Springer
    Nature. <a href="https://doi.org/10.1007/s00029-020-00553-x">https://doi.org/10.1007/s00029-020-00553-x</a>
  chicago: Minets, Sasha. “Cohomological Hall Algebras for Higgs Torsion Sheaves,
    Moduli of Triples and Sheaves on Surfaces.” <i>Selecta Mathematica, New Series</i>.
    Springer Nature, 2020. <a href="https://doi.org/10.1007/s00029-020-00553-x">https://doi.org/10.1007/s00029-020-00553-x</a>.
  ieee: S. Minets, “Cohomological Hall algebras for Higgs torsion sheaves, moduli
    of triples and sheaves on surfaces,” <i>Selecta Mathematica, New Series</i>, vol.
    26, no. 2. Springer Nature, 2020.
  ista: Minets S. 2020. Cohomological Hall algebras for Higgs torsion sheaves, moduli
    of triples and sheaves on surfaces. Selecta Mathematica, New Series. 26(2), 30.
  mla: Minets, Sasha. “Cohomological Hall Algebras for Higgs Torsion Sheaves, Moduli
    of Triples and Sheaves on Surfaces.” <i>Selecta Mathematica, New Series</i>, vol.
    26, no. 2, 30, Springer Nature, 2020, doi:<a href="https://doi.org/10.1007/s00029-020-00553-x">10.1007/s00029-020-00553-x</a>.
  short: S. Minets, Selecta Mathematica, New Series 26 (2020).
corr_author: '1'
date_created: 2020-04-26T22:00:44Z
date_published: 2020-04-15T00:00:00Z
date_updated: 2025-05-20T10:38:32Z
day: '15'
ddc:
- '510'
department:
- _id: TaHa
doi: 10.1007/s00029-020-00553-x
external_id:
  arxiv:
  - '1801.01429'
  isi:
  - '000526036400001'
file:
- access_level: open_access
  checksum: 2368c4662629b4759295eb365323b2ad
  content_type: application/pdf
  creator: dernst
  date_created: 2020-04-28T10:57:58Z
  date_updated: 2020-07-14T12:48:02Z
  file_id: '7690'
  file_name: 2020_SelectaMathematica_Minets.pdf
  file_size: 792469
  relation: main_file
file_date_updated: 2020-07-14T12:48:02Z
has_accepted_license: '1'
intvolume: '        26'
isi: 1
issue: '2'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
project:
- _id: B67AFEDC-15C9-11EA-A837-991A96BB2854
  name: IST Austria Open Access Fund
publication: Selecta Mathematica, New Series
publication_identifier:
  eissn:
  - 1420-9020
  issn:
  - 1022-1824
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Cohomological Hall algebras for Higgs torsion sheaves, moduli of triples and
  sheaves on surfaces
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 9947682f-b9fa-11ee-9c4a-b3ffaafe6614
volume: 26
year: '2020'
...
---
_id: '7684'
article_processing_charge: No
article_type: original
author:
- first_name: Igor
  full_name: Gridchyn, Igor
  id: 4B60654C-F248-11E8-B48F-1D18A9856A87
  last_name: Gridchyn
  orcid: 0000-0002-1807-1929
- first_name: Philipp
  full_name: Schönenberger, Philipp
  id: 3B9D816C-F248-11E8-B48F-1D18A9856A87
  last_name: Schönenberger
- first_name: Joseph
  full_name: O'Neill, Joseph
  id: 426376DC-F248-11E8-B48F-1D18A9856A87
  last_name: O'Neill
- first_name: Jozsef L
  full_name: Csicsvari, Jozsef L
  id: 3FA14672-F248-11E8-B48F-1D18A9856A87
  last_name: Csicsvari
  orcid: 0000-0002-5193-4036
citation:
  ama: Gridchyn I, Schönenberger P, O’Neill J, Csicsvari JL. Assembly-specific disruption
    of hippocampal replay leads to selective memory deficit. <i>Neuron</i>. 2020;106(2):291-300.e6.
    doi:<a href="https://doi.org/10.1016/j.neuron.2020.01.021">10.1016/j.neuron.2020.01.021</a>
  apa: Gridchyn, I., Schönenberger, P., O’Neill, J., &#38; Csicsvari, J. L. (2020).
    Assembly-specific disruption of hippocampal replay leads to selective memory deficit.
    <i>Neuron</i>. Elsevier. <a href="https://doi.org/10.1016/j.neuron.2020.01.021">https://doi.org/10.1016/j.neuron.2020.01.021</a>
  chicago: Gridchyn, Igor, Philipp Schönenberger, Joseph O’Neill, and Jozsef L Csicsvari.
    “Assembly-Specific Disruption of Hippocampal Replay Leads to Selective Memory
    Deficit.” <i>Neuron</i>. Elsevier, 2020. <a href="https://doi.org/10.1016/j.neuron.2020.01.021">https://doi.org/10.1016/j.neuron.2020.01.021</a>.
  ieee: I. Gridchyn, P. Schönenberger, J. O’Neill, and J. L. Csicsvari, “Assembly-specific
    disruption of hippocampal replay leads to selective memory deficit,” <i>Neuron</i>,
    vol. 106, no. 2. Elsevier, p. 291–300.e6, 2020.
  ista: Gridchyn I, Schönenberger P, O’Neill J, Csicsvari JL. 2020. Assembly-specific
    disruption of hippocampal replay leads to selective memory deficit. Neuron. 106(2),
    291–300.e6.
  mla: Gridchyn, Igor, et al. “Assembly-Specific Disruption of Hippocampal Replay
    Leads to Selective Memory Deficit.” <i>Neuron</i>, vol. 106, no. 2, Elsevier,
    2020, p. 291–300.e6, doi:<a href="https://doi.org/10.1016/j.neuron.2020.01.021">10.1016/j.neuron.2020.01.021</a>.
  short: I. Gridchyn, P. Schönenberger, J. O’Neill, J.L. Csicsvari, Neuron 106 (2020)
    291–300.e6.
date_created: 2020-04-26T22:00:45Z
date_published: 2020-04-22T00:00:00Z
date_updated: 2025-04-15T07:21:16Z
day: '22'
department:
- _id: JoCs
doi: 10.1016/j.neuron.2020.01.021
ec_funded: 1
external_id:
  isi:
  - '000528268200013'
  pmid:
  - '32070475'
intvolume: '       106'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.neuron.2020.01.021
month: '04'
oa: 1
oa_version: Published Version
page: 291-300.e6
pmid: 1
project:
- _id: 257A4776-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '281511'
  name: Memory-related information processing in neuronal circuits of the hippocampus
    and entorhinal cortex
publication: Neuron
publication_identifier:
  eissn:
  - '10974199'
  issn:
  - '08966273'
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
  link:
  - description: News on IST Homepage
    relation: press_release
    url: https://ist.ac.at/en/news/librarian-of-memory/
scopus_import: '1'
status: public
title: Assembly-specific disruption of hippocampal replay leads to selective memory
  deficit
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 106
year: '2020'
...
---
_id: '7686'
abstract:
- lang: eng
  text: 'The agricultural green revolution spectacularly enhanced crop yield and lodging
    resistance with modified DELLA-mediated gibberellin signaling. However, this was
    achieved at the expense of reduced nitrogen-use efficiency (NUE). Recently, Wu
    et al. revealed novel gibberellin signaling that provides a blueprint for improving
    tillering and NUE in Green Revolution varieties (GRVs). '
article_processing_charge: No
article_type: original
author:
- first_name: Huidan
  full_name: Xue, Huidan
  last_name: Xue
- first_name: Yuzhou
  full_name: Zhang, Yuzhou
  id: 3B6137F2-F248-11E8-B48F-1D18A9856A87
  last_name: Zhang
  orcid: 0000-0003-2627-6956
- first_name: Guanghui
  full_name: Xiao, Guanghui
  last_name: Xiao
citation:
  ama: 'Xue H, Zhang Y, Xiao G. Neo-gibberellin signaling: Guiding the next generation
    of the green revolution. <i>Trends in Plant Science</i>. 2020;25(6):520-522. doi:<a
    href="https://doi.org/10.1016/j.tplants.2020.04.001">10.1016/j.tplants.2020.04.001</a>'
  apa: 'Xue, H., Zhang, Y., &#38; Xiao, G. (2020). Neo-gibberellin signaling: Guiding
    the next generation of the green revolution. <i>Trends in Plant Science</i>. Elsevier.
    <a href="https://doi.org/10.1016/j.tplants.2020.04.001">https://doi.org/10.1016/j.tplants.2020.04.001</a>'
  chicago: 'Xue, Huidan, Yuzhou Zhang, and Guanghui Xiao. “Neo-Gibberellin Signaling:
    Guiding the next Generation of the Green Revolution.” <i>Trends in Plant Science</i>.
    Elsevier, 2020. <a href="https://doi.org/10.1016/j.tplants.2020.04.001">https://doi.org/10.1016/j.tplants.2020.04.001</a>.'
  ieee: 'H. Xue, Y. Zhang, and G. Xiao, “Neo-gibberellin signaling: Guiding the next
    generation of the green revolution,” <i>Trends in Plant Science</i>, vol. 25,
    no. 6. Elsevier, pp. 520–522, 2020.'
  ista: 'Xue H, Zhang Y, Xiao G. 2020. Neo-gibberellin signaling: Guiding the next
    generation of the green revolution. Trends in Plant Science. 25(6), 520–522.'
  mla: 'Xue, Huidan, et al. “Neo-Gibberellin Signaling: Guiding the next Generation
    of the Green Revolution.” <i>Trends in Plant Science</i>, vol. 25, no. 6, Elsevier,
    2020, pp. 520–22, doi:<a href="https://doi.org/10.1016/j.tplants.2020.04.001">10.1016/j.tplants.2020.04.001</a>.'
  short: H. Xue, Y. Zhang, G. Xiao, Trends in Plant Science 25 (2020) 520–522.
date_created: 2020-04-26T22:00:46Z
date_published: 2020-06-01T00:00:00Z
date_updated: 2025-06-25T10:59:39Z
day: '01'
department:
- _id: JiFr
doi: 10.1016/j.tplants.2020.04.001
external_id:
  isi:
  - '000533518400003'
  pmid:
  - '32407691'
intvolume: '        25'
isi: 1
issue: '6'
language:
- iso: eng
month: '06'
oa_version: None
page: 520-522
pmid: 1
publication: Trends in Plant Science
publication_identifier:
  issn:
  - 1360-1385
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Neo-gibberellin signaling: Guiding the next generation of the green revolution'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 25
year: '2020'
...
---
_id: '7689'
abstract:
- lang: eng
  text: "These are the supplementary research data to the publication \"Zero field
    splitting of heavy-hole states in quantum dots\". All matrix files have the same
    format. Within each column the bias voltage is changed. Each column corresponds
    to either a different gate voltage or magnetic field. The voltage values are given
    in mV, the current values in pA. Find a specific description in the included Readme
    file.\r\n"
article_processing_charge: No
author:
- first_name: Georgios
  full_name: Katsaros, Georgios
  id: 38DB5788-F248-11E8-B48F-1D18A9856A87
  last_name: Katsaros
  orcid: 0000-0001-8342-202X
citation:
  ama: Katsaros G. Supplementary data for “Zero field splitting of heavy-hole states
    in quantum dots.” 2020. doi:<a href="https://doi.org/10.15479/AT:ISTA:7689">10.15479/AT:ISTA:7689</a>
  apa: Katsaros, G. (2020). Supplementary data for “Zero field splitting of heavy-hole
    states in quantum dots.” Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:7689">https://doi.org/10.15479/AT:ISTA:7689</a>
  chicago: Katsaros, Georgios. “Supplementary Data for ‘Zero Field Splitting of Heavy-Hole
    States in Quantum Dots.’” Institute of Science and Technology Austria, 2020. <a
    href="https://doi.org/10.15479/AT:ISTA:7689">https://doi.org/10.15479/AT:ISTA:7689</a>.
  ieee: G. Katsaros, “Supplementary data for ‘Zero field splitting of heavy-hole states
    in quantum dots.’” Institute of Science and Technology Austria, 2020.
  ista: Katsaros G. 2020. Supplementary data for ‘Zero field splitting of heavy-hole
    states in quantum dots’, Institute of Science and Technology Austria, <a href="https://doi.org/10.15479/AT:ISTA:7689">10.15479/AT:ISTA:7689</a>.
  mla: Katsaros, Georgios. <i>Supplementary Data for “Zero Field Splitting of Heavy-Hole
    States in Quantum Dots.”</i> Institute of Science and Technology Austria, 2020,
    doi:<a href="https://doi.org/10.15479/AT:ISTA:7689">10.15479/AT:ISTA:7689</a>.
  short: G. Katsaros, (2020).
contributor:
- contributor_type: contact_person
  first_name: Georgios
  id: 38DB5788-F248-11E8-B48F-1D18A9856A87
  last_name: Katsaros
corr_author: '1'
date_created: 2020-05-01T15:14:46Z
date_published: 2020-05-01T00:00:00Z
date_updated: 2025-04-15T08:39:16Z
day: '01'
ddc:
- '530'
department:
- _id: GeKa
doi: 10.15479/AT:ISTA:7689
ec_funded: 1
file:
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  checksum: d23c0cb9e2d19e14e2f902b88b97c05d
  content_type: application/x-zip-compressed
  creator: gkatsaro
  date_created: 2020-05-01T15:13:28Z
  date_updated: 2020-07-14T12:48:02Z
  file_id: '7786'
  file_name: DOI_ZeroFieldSplitting.zip
  file_size: 5514403
  relation: main_file
file_date_updated: 2020-07-14T12:48:02Z
has_accepted_license: '1'
month: '05'
oa: 1
oa_version: Published Version
project:
- _id: 237E5020-32DE-11EA-91FC-C7463DDC885E
  call_identifier: H2020
  grant_number: '862046'
  name: TOPOLOGICALLY PROTECTED AND SCALABLE QUANTUM BITS
- _id: 237B3DA4-32DE-11EA-91FC-C7463DDC885E
  call_identifier: FWF
  grant_number: P32235
  name: Towards scalable hut wire quantum devices
publisher: Institute of Science and Technology Austria
related_material:
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  - id: '8203'
    relation: used_in_publication
    status: public
status: public
title: Supplementary data for "Zero field splitting of heavy-hole states in quantum
  dots"
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...
---
_id: '7695'
abstract:
- lang: eng
  text: The TPLATE complex (TPC) is a key endocytic adaptor protein complex in plants.
    TPC in Arabidopsis (Arabidopsis thaliana) contains six evolutionarily conserved
    subunits and two plant-specific subunits, AtEH1/Pan1 and AtEH2/Pan1, although
    cytoplasmic proteins are not associated with the hexameric subcomplex in the cytoplasm.
    To investigate the dynamic assembly of the octameric TPC at the plasma membrane
    (PM), we performed state-of-the-art dual-color live cell imaging at physiological
    and lowered temperatures. Lowering the temperature slowed down endocytosis, thereby
    enhancing the temporal resolution of the differential recruitment of endocytic
    components. Under both normal and lowered temperature conditions, the core TPC
    subunit TPLATE and the AtEH/Pan1 proteins exhibited simultaneous recruitment at
    the PM. These results, together with co-localization analysis of different TPC
    subunits, allow us to conclude that TPC in plant cells is not recruited to the
    PM sequentially but as an octameric complex.
article_processing_charge: No
article_type: original
author:
- first_name: J
  full_name: Wang, J
  last_name: Wang
- first_name: E
  full_name: Mylle, E
  last_name: Mylle
- first_name: Alexander J
  full_name: Johnson, Alexander J
  id: 46A62C3A-F248-11E8-B48F-1D18A9856A87
  last_name: Johnson
  orcid: 0000-0002-2739-8843
- first_name: N
  full_name: Besbrugge, N
  last_name: Besbrugge
- first_name: G
  full_name: De Jaeger, G
  last_name: De Jaeger
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: R
  full_name: Pleskot, R
  last_name: Pleskot
- first_name: D
  full_name: van Damme, D
  last_name: van Damme
citation:
  ama: Wang J, Mylle E, Johnson AJ, et al. High temporal resolution reveals simultaneous
    plasma membrane recruitment of TPLATE complex subunits. <i>Plant Physiology</i>.
    2020;183(3):986-997. doi:<a href="https://doi.org/10.1104/pp.20.00178">10.1104/pp.20.00178</a>
  apa: Wang, J., Mylle, E., Johnson, A. J., Besbrugge, N., De Jaeger, G., Friml, J.,
    … van Damme, D. (2020). High temporal resolution reveals simultaneous plasma membrane
    recruitment of TPLATE complex subunits. <i>Plant Physiology</i>. American Society
    of Plant Biologists. <a href="https://doi.org/10.1104/pp.20.00178">https://doi.org/10.1104/pp.20.00178</a>
  chicago: Wang, J, E Mylle, Alexander J Johnson, N Besbrugge, G De Jaeger, Jiří Friml,
    R Pleskot, and D van Damme. “High Temporal Resolution Reveals Simultaneous Plasma
    Membrane Recruitment of TPLATE Complex Subunits.” <i>Plant Physiology</i>. American
    Society of Plant Biologists, 2020. <a href="https://doi.org/10.1104/pp.20.00178">https://doi.org/10.1104/pp.20.00178</a>.
  ieee: J. Wang <i>et al.</i>, “High temporal resolution reveals simultaneous plasma
    membrane recruitment of TPLATE complex subunits,” <i>Plant Physiology</i>, vol.
    183, no. 3. American Society of Plant Biologists, pp. 986–997, 2020.
  ista: Wang J, Mylle E, Johnson AJ, Besbrugge N, De Jaeger G, Friml J, Pleskot R,
    van Damme D. 2020. High temporal resolution reveals simultaneous plasma membrane
    recruitment of TPLATE complex subunits. Plant Physiology. 183(3), 986–997.
  mla: Wang, J., et al. “High Temporal Resolution Reveals Simultaneous Plasma Membrane
    Recruitment of TPLATE Complex Subunits.” <i>Plant Physiology</i>, vol. 183, no.
    3, American Society of Plant Biologists, 2020, pp. 986–97, doi:<a href="https://doi.org/10.1104/pp.20.00178">10.1104/pp.20.00178</a>.
  short: J. Wang, E. Mylle, A.J. Johnson, N. Besbrugge, G. De Jaeger, J. Friml, R.
    Pleskot, D. van Damme, Plant Physiology 183 (2020) 986–997.
date_created: 2020-04-29T15:23:00Z
date_published: 2020-07-01T00:00:00Z
date_updated: 2025-04-15T07:32:09Z
day: '01'
department:
- _id: JiFr
doi: 10.1104/pp.20.00178
external_id:
  isi:
  - '000550682000018'
  pmid:
  - '32321842'
intvolume: '       183'
isi: 1
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/2020.02.13.948109
month: '07'
oa: 1
oa_version: Preprint
page: 986-997
pmid: 1
project:
- _id: 26538374-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I03630
  name: Molecular mechanisms of endocytic cargo recognition in plants
publication: Plant Physiology
publication_identifier:
  eissn:
  - 1532-2548
  issn:
  - 0032-0889
publication_status: published
publisher: American Society of Plant Biologists
quality_controlled: '1'
scopus_import: '1'
status: public
title: High temporal resolution reveals simultaneous plasma membrane recruitment of
  TPLATE complex subunits
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 183
year: '2020'
...
---
_id: '7697'
abstract:
- lang: eng
  text: "* Morphogenesis and adaptive tropic growth in plants depend on gradients
    of the phytohormone auxin, mediated by the membrane‐based PIN‐FORMED (PIN) auxin
    transporters. PINs localize to a particular side of the plasma membrane (PM) or
    to the endoplasmic reticulum (ER) to directionally transport auxin and maintain
    intercellular and intracellular auxin homeostasis, respectively. However, the
    molecular cues that confer their diverse cellular localizations remain largely
    unknown.\r\n* In this study, we systematically swapped the domains between ER‐
    and PM‐localized PIN proteins, as well as between apical and basal PM‐localized
    PINs from Arabidopsis thaliana , to shed light on why PIN family members with
    similar topological structures reside at different membrane compartments within
    cells.\r\n* Our results show that not only do the N‐ and C‐terminal transmembrane
    domains (TMDs) and central hydrophilic loop contribute to their differential subcellular
    localizations and cellular polarity, but that the pairwise‐matched N‐ and C‐terminal
    TMDs resulting from intramolecular domain–domain coevolution are also crucial
    for their divergent patterns of localization.\r\n* These findings illustrate the
    complexity of the evolutionary path of PIN proteins in acquiring their plethora
    of developmental functions and adaptive growth in plants."
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Yuzhou
  full_name: Zhang, Yuzhou
  id: 3B6137F2-F248-11E8-B48F-1D18A9856A87
  last_name: Zhang
  orcid: 0000-0003-2627-6956
- first_name: Corinna
  full_name: Hartinger, Corinna
  id: AEFB2266-8ABF-11EA-AA39-812C3623CBE4
  last_name: Hartinger
  orcid: 0000-0003-1618-2737
- first_name: Xiaojuan
  full_name: Wang, Xiaojuan
  last_name: Wang
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Zhang Y, Hartinger C, Wang X, Friml J. Directional auxin fluxes in plants by
    intramolecular domain‐domain co‐evolution of PIN auxin transporters. <i>New Phytologist</i>.
    2020;227(5):1406-1416. doi:<a href="https://doi.org/10.1111/nph.16629">10.1111/nph.16629</a>
  apa: Zhang, Y., Hartinger, C., Wang, X., &#38; Friml, J. (2020). Directional auxin
    fluxes in plants by intramolecular domain‐domain co‐evolution of PIN auxin transporters.
    <i>New Phytologist</i>. Wiley. <a href="https://doi.org/10.1111/nph.16629">https://doi.org/10.1111/nph.16629</a>
  chicago: Zhang, Yuzhou, Corinna Hartinger, Xiaojuan Wang, and Jiří Friml. “Directional
    Auxin Fluxes in Plants by Intramolecular Domain‐domain Co‐evolution of PIN Auxin
    Transporters.” <i>New Phytologist</i>. Wiley, 2020. <a href="https://doi.org/10.1111/nph.16629">https://doi.org/10.1111/nph.16629</a>.
  ieee: Y. Zhang, C. Hartinger, X. Wang, and J. Friml, “Directional auxin fluxes in
    plants by intramolecular domain‐domain co‐evolution of PIN auxin transporters,”
    <i>New Phytologist</i>, vol. 227, no. 5. Wiley, pp. 1406–1416, 2020.
  ista: Zhang Y, Hartinger C, Wang X, Friml J. 2020. Directional auxin fluxes in plants
    by intramolecular domain‐domain co‐evolution of PIN auxin transporters. New Phytologist.
    227(5), 1406–1416.
  mla: Zhang, Yuzhou, et al. “Directional Auxin Fluxes in Plants by Intramolecular
    Domain‐domain Co‐evolution of PIN Auxin Transporters.” <i>New Phytologist</i>,
    vol. 227, no. 5, Wiley, 2020, pp. 1406–16, doi:<a href="https://doi.org/10.1111/nph.16629">10.1111/nph.16629</a>.
  short: Y. Zhang, C. Hartinger, X. Wang, J. Friml, New Phytologist 227 (2020) 1406–1416.
corr_author: '1'
date_created: 2020-04-30T08:43:29Z
date_published: 2020-09-01T00:00:00Z
date_updated: 2025-04-14T07:45:03Z
day: '01'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1111/nph.16629
ec_funded: 1
external_id:
  isi:
  - '000534092400001'
  pmid:
  - '32350870'
file:
- access_level: open_access
  checksum: 8e8150dbbba8cb65b72f81d1f0864b8b
  content_type: application/pdf
  creator: dernst
  date_created: 2020-11-24T12:19:38Z
  date_updated: 2020-11-24T12:19:38Z
  file_id: '8799'
  file_name: 2020_09_NewPhytologist_Zhang.pdf
  file_size: 3643395
  relation: main_file
  success: 1
file_date_updated: 2020-11-24T12:19:38Z
has_accepted_license: '1'
intvolume: '       227'
isi: 1
issue: '5'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: 1406-1416
pmid: 1
project:
- _id: 261099A6-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '742985'
  name: Tracing Evolution of Auxin Transport and Polarity in Plants
- _id: 26538374-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I03630
  name: Molecular mechanisms of endocytic cargo recognition in plants
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication: New Phytologist
publication_identifier:
  eissn:
  - 1469-8137
  issn:
  - 0028-646X
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Directional auxin fluxes in plants by intramolecular domain‐domain co‐evolution
  of PIN auxin transporters
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 227
year: '2020'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '7707'
abstract:
- lang: eng
  text: The growing sample size of genome-wide association studies has facilitated
    the discovery of gene-environment interactions (GxE). Here we propose a maximum
    likelihood method to estimate the contribution of GxE to continuous traits taking
    into account all interacting environmental variables, without the need to measure
    any. Extensive simulations demonstrate that our method provides unbiased interaction
    estimates and excellent coverage. We also offer strategies to distinguish specific
    GxE from general scale effects. Applying our method to 32 traits in the UK Biobank
    reveals that while the genetic risk score (GRS) of 376 variants explains 5.2%
    of body mass index (BMI) variance, GRSxE explains an additional 1.9%. Nevertheless,
    this interaction holds for any variable with identical correlation to BMI as the
    GRS, hence may not be GRS-specific. Still, we observe that the global contribution
    of specific GRSxE to complex traits is substantial for nine obesity-related measures
    (including leg impedance and trunk fat-free mass).
article_number: '1385'
article_processing_charge: No
article_type: original
author:
- first_name: Jonathan
  full_name: Sulc, Jonathan
  last_name: Sulc
- first_name: Ninon
  full_name: Mounier, Ninon
  last_name: Mounier
- first_name: Felix
  full_name: Günther, Felix
  last_name: Günther
- first_name: Thomas
  full_name: Winkler, Thomas
  last_name: Winkler
- first_name: Andrew R.
  full_name: Wood, Andrew R.
  last_name: Wood
- first_name: Timothy M.
  full_name: Frayling, Timothy M.
  last_name: Frayling
- first_name: Iris M.
  full_name: Heid, Iris M.
  last_name: Heid
- first_name: Matthew Richard
  full_name: Robinson, Matthew Richard
  id: E5D42276-F5DA-11E9-8E24-6303E6697425
  last_name: Robinson
  orcid: 0000-0001-8982-8813
- first_name: Zoltán
  full_name: Kutalik, Zoltán
  last_name: Kutalik
citation:
  ama: Sulc J, Mounier N, Günther F, et al. Quantification of the overall contribution
    of gene-environment interaction for obesity-related traits. <i>Nature Communications</i>.
    2020;11. doi:<a href="https://doi.org/10.1038/s41467-020-15107-0">10.1038/s41467-020-15107-0</a>
  apa: Sulc, J., Mounier, N., Günther, F., Winkler, T., Wood, A. R., Frayling, T.
    M., … Kutalik, Z. (2020). Quantification of the overall contribution of gene-environment
    interaction for obesity-related traits. <i>Nature Communications</i>. Springer
    Nature. <a href="https://doi.org/10.1038/s41467-020-15107-0">https://doi.org/10.1038/s41467-020-15107-0</a>
  chicago: Sulc, Jonathan, Ninon Mounier, Felix Günther, Thomas Winkler, Andrew R.
    Wood, Timothy M. Frayling, Iris M. Heid, Matthew Richard Robinson, and Zoltán
    Kutalik. “Quantification of the Overall Contribution of Gene-Environment Interaction
    for Obesity-Related Traits.” <i>Nature Communications</i>. Springer Nature, 2020.
    <a href="https://doi.org/10.1038/s41467-020-15107-0">https://doi.org/10.1038/s41467-020-15107-0</a>.
  ieee: J. Sulc <i>et al.</i>, “Quantification of the overall contribution of gene-environment
    interaction for obesity-related traits,” <i>Nature Communications</i>, vol. 11.
    Springer Nature, 2020.
  ista: Sulc J, Mounier N, Günther F, Winkler T, Wood AR, Frayling TM, Heid IM, Robinson
    MR, Kutalik Z. 2020. Quantification of the overall contribution of gene-environment
    interaction for obesity-related traits. Nature Communications. 11, 1385.
  mla: Sulc, Jonathan, et al. “Quantification of the Overall Contribution of Gene-Environment
    Interaction for Obesity-Related Traits.” <i>Nature Communications</i>, vol. 11,
    1385, Springer Nature, 2020, doi:<a href="https://doi.org/10.1038/s41467-020-15107-0">10.1038/s41467-020-15107-0</a>.
  short: J. Sulc, N. Mounier, F. Günther, T. Winkler, A.R. Wood, T.M. Frayling, I.M.
    Heid, M.R. Robinson, Z. Kutalik, Nature Communications 11 (2020).
date_created: 2020-04-30T10:39:33Z
date_published: 2020-03-20T00:00:00Z
date_updated: 2024-10-15T12:43:32Z
day: '20'
doi: 10.1038/s41467-020-15107-0
extern: '1'
intvolume: '        11'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1038/s41467-020-15107-0
month: '03'
oa: 1
oa_version: Published Version
publication: Nature Communications
publication_identifier:
  issn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Quantification of the overall contribution of gene-environment interaction
  for obesity-related traits
type: journal_article
user_id: 0043cee0-e5fc-11ee-9736-f83bc23afbf0
volume: 11
year: '2020'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '7708'
abstract:
- lang: eng
  text: We conducted DNA methylation association analyses using Illumina 450K data
    from whole blood for an Australian amyotrophic lateral sclerosis (ALS) case–control
    cohort (782 cases and 613 controls). Analyses used mixed linear models as implemented
    in the OSCA software. We found a significantly higher proportion of neutrophils
    in cases compared to controls which replicated in an independent cohort from the
    Netherlands (1159 cases and 637 controls). The OSCA MOMENT linear mixed model
    has been shown in simulations to best account for confounders. When combined in
    a methylation profile score, the 25 most-associated probes identified by MOMENT
    significantly classified case–control status in the Netherlands sample (area under
    the curve, AUC = 0.65, CI95% = [0.62–0.68], p = 8.3 × 10−22). The maximum AUC
    achieved was 0.69 (CI95% = [0.66–0.71], p = 4.3 × 10−34) when cell-type proportion
    was included in the predictor.
article_number: '10'
article_processing_charge: No
article_type: original
author:
- first_name: Marta F.
  full_name: Nabais, Marta F.
  last_name: Nabais
- first_name: Tian
  full_name: Lin, Tian
  last_name: Lin
- first_name: Beben
  full_name: Benyamin, Beben
  last_name: Benyamin
- first_name: Kelly L.
  full_name: Williams, Kelly L.
  last_name: Williams
- first_name: Fleur C.
  full_name: Garton, Fleur C.
  last_name: Garton
- first_name: Anna A. E.
  full_name: Vinkhuyzen, Anna A. E.
  last_name: Vinkhuyzen
- first_name: Futao
  full_name: Zhang, Futao
  last_name: Zhang
- first_name: Costanza L.
  full_name: Vallerga, Costanza L.
  last_name: Vallerga
- first_name: Restuadi
  full_name: Restuadi, Restuadi
  last_name: Restuadi
- first_name: Anna
  full_name: Freydenzon, Anna
  last_name: Freydenzon
- first_name: Ramona A. J.
  full_name: Zwamborn, Ramona A. J.
  last_name: Zwamborn
- first_name: Paul J.
  full_name: Hop, Paul J.
  last_name: Hop
- first_name: Matthew Richard
  full_name: Robinson, Matthew Richard
  id: E5D42276-F5DA-11E9-8E24-6303E6697425
  last_name: Robinson
  orcid: 0000-0001-8982-8813
- first_name: Jacob
  full_name: Gratten, Jacob
  last_name: Gratten
- first_name: Peter M.
  full_name: Visscher, Peter M.
  last_name: Visscher
- first_name: Eilis
  full_name: Hannon, Eilis
  last_name: Hannon
- first_name: Jonathan
  full_name: Mill, Jonathan
  last_name: Mill
- first_name: Matthew A.
  full_name: Brown, Matthew A.
  last_name: Brown
- first_name: Nigel G.
  full_name: Laing, Nigel G.
  last_name: Laing
- first_name: Karen A.
  full_name: Mather, Karen A.
  last_name: Mather
- first_name: Perminder S.
  full_name: Sachdev, Perminder S.
  last_name: Sachdev
- first_name: Shyuan T.
  full_name: Ngo, Shyuan T.
  last_name: Ngo
- first_name: Frederik J.
  full_name: Steyn, Frederik J.
  last_name: Steyn
- first_name: Leanne
  full_name: Wallace, Leanne
  last_name: Wallace
- first_name: Anjali K.
  full_name: Henders, Anjali K.
  last_name: Henders
- first_name: Merrilee
  full_name: Needham, Merrilee
  last_name: Needham
- first_name: Jan H.
  full_name: Veldink, Jan H.
  last_name: Veldink
- first_name: Susan
  full_name: Mathers, Susan
  last_name: Mathers
- first_name: Garth
  full_name: Nicholson, Garth
  last_name: Nicholson
- first_name: Dominic B.
  full_name: Rowe, Dominic B.
  last_name: Rowe
- first_name: Robert D.
  full_name: Henderson, Robert D.
  last_name: Henderson
- first_name: Pamela A.
  full_name: McCombe, Pamela A.
  last_name: McCombe
- first_name: Roger
  full_name: Pamphlett, Roger
  last_name: Pamphlett
- first_name: Jian
  full_name: Yang, Jian
  last_name: Yang
- first_name: Ian P.
  full_name: Blair, Ian P.
  last_name: Blair
- first_name: Allan F.
  full_name: McRae, Allan F.
  last_name: McRae
- first_name: Naomi R.
  full_name: Wray, Naomi R.
  last_name: Wray
citation:
  ama: Nabais MF, Lin T, Benyamin B, et al. Significant out-of-sample classification
    from methylation profile scoring for amyotrophic lateral sclerosis. <i>npj Genomic
    Medicine</i>. 2020;5. doi:<a href="https://doi.org/10.1038/s41525-020-0118-3">10.1038/s41525-020-0118-3</a>
  apa: Nabais, M. F., Lin, T., Benyamin, B., Williams, K. L., Garton, F. C., Vinkhuyzen,
    A. A. E., … Wray, N. R. (2020). Significant out-of-sample classification from
    methylation profile scoring for amyotrophic lateral sclerosis. <i>Npj Genomic
    Medicine</i>. Springer Nature. <a href="https://doi.org/10.1038/s41525-020-0118-3">https://doi.org/10.1038/s41525-020-0118-3</a>
  chicago: Nabais, Marta F., Tian Lin, Beben Benyamin, Kelly L. Williams, Fleur C.
    Garton, Anna A. E. Vinkhuyzen, Futao Zhang, et al. “Significant Out-of-Sample
    Classification from Methylation Profile Scoring for Amyotrophic Lateral Sclerosis.”
    <i>Npj Genomic Medicine</i>. Springer Nature, 2020. <a href="https://doi.org/10.1038/s41525-020-0118-3">https://doi.org/10.1038/s41525-020-0118-3</a>.
  ieee: M. F. Nabais <i>et al.</i>, “Significant out-of-sample classification from
    methylation profile scoring for amyotrophic lateral sclerosis,” <i>npj Genomic
    Medicine</i>, vol. 5. Springer Nature, 2020.
  ista: Nabais MF, Lin T, Benyamin B, Williams KL, Garton FC, Vinkhuyzen AAE, Zhang
    F, Vallerga CL, Restuadi R, Freydenzon A, Zwamborn RAJ, Hop PJ, Robinson MR, Gratten
    J, Visscher PM, Hannon E, Mill J, Brown MA, Laing NG, Mather KA, Sachdev PS, Ngo
    ST, Steyn FJ, Wallace L, Henders AK, Needham M, Veldink JH, Mathers S, Nicholson
    G, Rowe DB, Henderson RD, McCombe PA, Pamphlett R, Yang J, Blair IP, McRae AF,
    Wray NR. 2020. Significant out-of-sample classification from methylation profile
    scoring for amyotrophic lateral sclerosis. npj Genomic Medicine. 5, 10.
  mla: Nabais, Marta F., et al. “Significant Out-of-Sample Classification from Methylation
    Profile Scoring for Amyotrophic Lateral Sclerosis.” <i>Npj Genomic Medicine</i>,
    vol. 5, 10, Springer Nature, 2020, doi:<a href="https://doi.org/10.1038/s41525-020-0118-3">10.1038/s41525-020-0118-3</a>.
  short: M.F. Nabais, T. Lin, B. Benyamin, K.L. Williams, F.C. Garton, A.A.E. Vinkhuyzen,
    F. Zhang, C.L. Vallerga, R. Restuadi, A. Freydenzon, R.A.J. Zwamborn, P.J. Hop,
    M.R. Robinson, J. Gratten, P.M. Visscher, E. Hannon, J. Mill, M.A. Brown, N.G.
    Laing, K.A. Mather, P.S. Sachdev, S.T. Ngo, F.J. Steyn, L. Wallace, A.K. Henders,
    M. Needham, J.H. Veldink, S. Mathers, G. Nicholson, D.B. Rowe, R.D. Henderson,
    P.A. McCombe, R. Pamphlett, J. Yang, I.P. Blair, A.F. McRae, N.R. Wray, Npj Genomic
    Medicine 5 (2020).
date_created: 2020-04-30T10:39:54Z
date_published: 2020-02-27T00:00:00Z
date_updated: 2024-10-15T12:41:56Z
day: '27'
doi: 10.1038/s41525-020-0118-3
extern: '1'
intvolume: '         5'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1038/s41525-020-0118-3
month: '02'
oa: 1
oa_version: Published Version
publication: npj Genomic Medicine
publication_identifier:
  issn:
  - 2056-7944
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Significant out-of-sample classification from methylation profile scoring for
  amyotrophic lateral sclerosis
type: journal_article
user_id: 0043cee0-e5fc-11ee-9736-f83bc23afbf0
volume: 5
year: '2020'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '7778'
abstract:
- lang: eng
  text: Recent advances in synthetic posttranslational protein circuits are substantially
    impacting the landscape of cellular engineering and offer several advantages compared
    to traditional gene circuits. However, engineering dynamic phenomena such as oscillations
    in protein-level circuits remains an outstanding challenge. Few examples of biological
    posttranslational oscillators are known, necessitating theoretical progress to
    determine realizable oscillators. We construct mathematical models for two posttranslational
    oscillators, using few components that interact only through reversible binding
    and phosphorylation/dephosphorylation reactions. Our designed oscillators rely
    on the self-assembly of two protein species into multimeric functional enzymes
    that respectively inhibit and enhance this self-assembly. We limit our analysis
    to within experimental constraints, finding (i) significant portions of the restricted
    parameter space yielding oscillations and (ii) that oscillation periods can be
    tuned by several orders of magnitude using recent advances in computational protein
    design. Our work paves the way for the rational design and realization of protein-based
    dynamic systems.
article_number: eabc1939
article_processing_charge: No
article_type: original
author:
- first_name: Ofer
  full_name: Kimchi, Ofer
  last_name: Kimchi
- first_name: Carl Peter
  full_name: Goodrich, Carl Peter
  id: EB352CD2-F68A-11E9-89C5-A432E6697425
  last_name: Goodrich
  orcid: 0000-0002-1307-5074
- first_name: Alexis
  full_name: Courbet, Alexis
  last_name: Courbet
- first_name: Agnese I.
  full_name: Curatolo, Agnese I.
  last_name: Curatolo
- first_name: Nicholas B.
  full_name: Woodall, Nicholas B.
  last_name: Woodall
- first_name: David
  full_name: Baker, David
  last_name: Baker
- first_name: Michael P.
  full_name: Brenner, Michael P.
  last_name: Brenner
citation:
  ama: Kimchi O, Goodrich CP, Courbet A, et al. Self-assembly-based posttranslational
    protein oscillators. <i>Science Advances</i>. 2020;6(51). doi:<a href="https://doi.org/10.1126/sciadv.abc1939">10.1126/sciadv.abc1939</a>
  apa: Kimchi, O., Goodrich, C. P., Courbet, A., Curatolo, A. I., Woodall, N. B.,
    Baker, D., &#38; Brenner, M. P. (2020). Self-assembly-based posttranslational
    protein oscillators. <i>Science Advances</i>. <a href="https://doi.org/10.1126/sciadv.abc1939">https://doi.org/10.1126/sciadv.abc1939</a>
  chicago: Kimchi, Ofer, Carl Peter Goodrich, Alexis Courbet, Agnese I. Curatolo,
    Nicholas B. Woodall, David Baker, and Michael P. Brenner. “Self-Assembly-Based
    Posttranslational Protein Oscillators.” <i>Science Advances</i>, 2020. <a href="https://doi.org/10.1126/sciadv.abc1939">https://doi.org/10.1126/sciadv.abc1939</a>.
  ieee: O. Kimchi <i>et al.</i>, “Self-assembly-based posttranslational protein oscillators,”
    <i>Science Advances</i>, vol. 6, no. 51. 2020.
  ista: Kimchi O, Goodrich CP, Courbet A, Curatolo AI, Woodall NB, Baker D, Brenner
    MP. 2020. Self-assembly-based posttranslational protein oscillators. Science Advances.
    6(51), eabc1939.
  mla: Kimchi, Ofer, et al. “Self-Assembly-Based Posttranslational Protein Oscillators.”
    <i>Science Advances</i>, vol. 6, no. 51, eabc1939, 2020, doi:<a href="https://doi.org/10.1126/sciadv.abc1939">10.1126/sciadv.abc1939</a>.
  short: O. Kimchi, C.P. Goodrich, A. Courbet, A.I. Curatolo, N.B. Woodall, D. Baker,
    M.P. Brenner, Science Advances 6 (2020).
date_created: 2020-04-30T12:07:55Z
date_published: 2020-12-16T00:00:00Z
date_updated: 2024-10-15T12:55:13Z
day: '16'
ddc:
- '570'
doi: 10.1126/sciadv.abc1939
extern: '1'
file:
- access_level: open_access
  checksum: eb6d950b6a68ddc4a2fb31ec80a2a1bd
  content_type: application/pdf
  creator: dernst
  date_created: 2021-04-12T08:33:23Z
  date_updated: 2021-04-12T08:33:23Z
  file_id: '9320'
  file_name: 2020_ScienceAdv_Kimchi.pdf
  file_size: 1259758
  relation: main_file
  success: 1
file_date_updated: 2021-04-12T08:33:23Z
has_accepted_license: '1'
intvolume: '         6'
issue: '51'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
publication: Science Advances
publication_status: published
quality_controlled: '1'
status: public
title: Self-assembly-based posttranslational protein oscillators
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 0043cee0-e5fc-11ee-9736-f83bc23afbf0
volume: 6
year: '2020'
...
---
_id: '7788'
abstract:
- lang: eng
  text: Mutations in NDUFS4, which encodes an accessory subunit of mitochondrial oxidative
    phosphorylation (OXPHOS) complex I (CI), induce Leigh syndrome (LS). LS is a poorly
    understood pediatric disorder featuring brain-specific anomalies and early death.
    To study the LS pathomechanism, we here compared OXPHOS proteomes between various
    Ndufs4−/− mouse tissues. Ndufs4−/− animals displayed significantly lower CI subunit
    levels in brain/diaphragm relative to other tissues (liver/heart/kidney/skeletal
    muscle), whereas other OXPHOS subunit levels were not reduced. Absence of NDUFS4
    induced near complete absence of the NDUFA12 accessory subunit, a 50% reduction
    in other CI subunit levels, and an increase in specific CI assembly factors. Among
    the latter, NDUFAF2 was most highly increased. Regarding NDUFS4, NDUFA12 and NDUFAF2,
    identical results were obtained in Ndufs4−/− mouse embryonic fibroblasts (MEFs)
    and NDUFS4-mutated LS patient cells. Ndufs4−/− MEFs contained active CI in situ
    but blue-native-PAGE highlighted that NDUFAF2 attached to an inactive CI subcomplex
    (CI-830) and inactive assemblies of higher MW. In NDUFA12-mutated LS patient cells,
    NDUFA12 absence did not reduce NDUFS4 levels but triggered NDUFAF2 association
    to active CI. BN-PAGE revealed no such association in LS patient fibroblasts with
    mutations in other CI subunit-encoding genes where NDUFAF2 was attached to CI-830
    (NDUFS1, NDUFV1 mutation) or not detected (NDUFS7 mutation). Supported by enzymological
    and CI in silico structural analysis, we conclude that absence of NDUFS4 induces
    near complete absence of NDUFA12 but not vice versa, and that NDUFAF2 stabilizes
    active CI in Ndufs4−/− mice and LS patient cells, perhaps in concert with mitochondrial
    inner membrane lipids.
article_number: '148213'
article_processing_charge: No
article_type: original
author:
- first_name: Merel J.W.
  full_name: Adjobo-Hermans, Merel J.W.
  last_name: Adjobo-Hermans
- first_name: Ria
  full_name: De Haas, Ria
  last_name: De Haas
- first_name: Peter H.G.M.
  full_name: Willems, Peter H.G.M.
  last_name: Willems
- first_name: Aleksandra
  full_name: Wojtala, Aleksandra
  last_name: Wojtala
- first_name: Sjenet E.
  full_name: Van Emst-De Vries, Sjenet E.
  last_name: Van Emst-De Vries
- first_name: Jori A.
  full_name: Wagenaars, Jori A.
  last_name: Wagenaars
- first_name: Mariel
  full_name: Van Den Brand, Mariel
  last_name: Van Den Brand
- first_name: Richard J.
  full_name: Rodenburg, Richard J.
  last_name: Rodenburg
- first_name: Jan A.M.
  full_name: Smeitink, Jan A.M.
  last_name: Smeitink
- first_name: Leo G.
  full_name: Nijtmans, Leo G.
  last_name: Nijtmans
- first_name: Leonid A
  full_name: Sazanov, Leonid A
  id: 338D39FE-F248-11E8-B48F-1D18A9856A87
  last_name: Sazanov
  orcid: 0000-0002-0977-7989
- first_name: Mariusz R.
  full_name: Wieckowski, Mariusz R.
  last_name: Wieckowski
- first_name: Werner J.H.
  full_name: Koopman, Werner J.H.
  last_name: Koopman
citation:
  ama: 'Adjobo-Hermans MJW, De Haas R, Willems PHGM, et al. NDUFS4 deletion triggers
    loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role
    for NDUFAF2. <i>Biochimica et Biophysica Acta - Bioenergetics</i>. 2020;1861(8).
    doi:<a href="https://doi.org/10.1016/j.bbabio.2020.148213">10.1016/j.bbabio.2020.148213</a>'
  apa: 'Adjobo-Hermans, M. J. W., De Haas, R., Willems, P. H. G. M., Wojtala, A.,
    Van Emst-De Vries, S. E., Wagenaars, J. A., … Koopman, W. J. H. (2020). NDUFS4
    deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients:
    A stabilizing role for NDUFAF2. <i>Biochimica et Biophysica Acta - Bioenergetics</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.bbabio.2020.148213">https://doi.org/10.1016/j.bbabio.2020.148213</a>'
  chicago: 'Adjobo-Hermans, Merel J.W., Ria De Haas, Peter H.G.M. Willems, Aleksandra
    Wojtala, Sjenet E. Van Emst-De Vries, Jori A. Wagenaars, Mariel Van Den Brand,
    et al. “NDUFS4 Deletion Triggers Loss of NDUFA12 in Ndufs4−/− Mice and Leigh Syndrome
    Patients: A Stabilizing Role for NDUFAF2.” <i>Biochimica et Biophysica Acta -
    Bioenergetics</i>. Elsevier, 2020. <a href="https://doi.org/10.1016/j.bbabio.2020.148213">https://doi.org/10.1016/j.bbabio.2020.148213</a>.'
  ieee: 'M. J. W. Adjobo-Hermans <i>et al.</i>, “NDUFS4 deletion triggers loss of
    NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for
    NDUFAF2,” <i>Biochimica et Biophysica Acta - Bioenergetics</i>, vol. 1861, no.
    8. Elsevier, 2020.'
  ista: 'Adjobo-Hermans MJW, De Haas R, Willems PHGM, Wojtala A, Van Emst-De Vries
    SE, Wagenaars JA, Van Den Brand M, Rodenburg RJ, Smeitink JAM, Nijtmans LG, Sazanov
    LA, Wieckowski MR, Koopman WJH. 2020. NDUFS4 deletion triggers loss of NDUFA12
    in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2.
    Biochimica et Biophysica Acta - Bioenergetics. 1861(8), 148213.'
  mla: 'Adjobo-Hermans, Merel J. W., et al. “NDUFS4 Deletion Triggers Loss of NDUFA12
    in Ndufs4−/− Mice and Leigh Syndrome Patients: A Stabilizing Role for NDUFAF2.”
    <i>Biochimica et Biophysica Acta - Bioenergetics</i>, vol. 1861, no. 8, 148213,
    Elsevier, 2020, doi:<a href="https://doi.org/10.1016/j.bbabio.2020.148213">10.1016/j.bbabio.2020.148213</a>.'
  short: M.J.W. Adjobo-Hermans, R. De Haas, P.H.G.M. Willems, A. Wojtala, S.E. Van
    Emst-De Vries, J.A. Wagenaars, M. Van Den Brand, R.J. Rodenburg, J.A.M. Smeitink,
    L.G. Nijtmans, L.A. Sazanov, M.R. Wieckowski, W.J.H. Koopman, Biochimica et Biophysica
    Acta - Bioenergetics 1861 (2020).
date_created: 2020-05-03T22:00:47Z
date_published: 2020-08-01T00:00:00Z
date_updated: 2025-07-10T11:54:47Z
day: '01'
ddc:
- '570'
department:
- _id: LeSa
doi: 10.1016/j.bbabio.2020.148213
external_id:
  isi:
  - '000540842000012'
  pmid:
  - '32335026'
file:
- access_level: open_access
  checksum: a9b152381307cf45fe266a8dc5640388
  content_type: application/pdf
  creator: dernst
  date_created: 2020-05-04T12:25:19Z
  date_updated: 2020-07-14T12:48:03Z
  file_id: '7798'
  file_name: 2020_BBA_Adjobo_Hermans.pdf
  file_size: 3826792
  relation: main_file
file_date_updated: 2020-07-14T12:48:03Z
has_accepted_license: '1'
intvolume: '      1861'
isi: 1
issue: '8'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
publication: Biochimica et Biophysica Acta - Bioenergetics
publication_identifier:
  eissn:
  - 1879-2650
  issn:
  - 0005-2728
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome
  patients: A stabilizing role for NDUFAF2'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1861
year: '2020'
...
