---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21159'
abstract:
- lang: eng
text: "One of the foundational theorems of extremal graph theory is Dirac’s theorem,
which\r\nsays that if an n-vertex graph G has minimum degree at least n/2, then
G has a\r\nHamilton cycle, and therefore a perfect matching (if n is even). Later
work by Sárközy,\r\nSelkow and Szemerédi showed that in fact Dirac graphs have
many Hamilton cycles\r\nand perfect matchings, culminating in a result of Cuckler
and Kahn that gives a precise\r\ndescription of the numbers of Hamilton cycles
and perfect matchings in a Dirac graph\r\nG (in terms of an entropy-like parameter
of G). In this paper we extend Cuckler\r\nand Kahn’s result to perfect matchings
in hypergraphs. For positive integers d < k,\r\nand for n divisible by k, let
md (k, n) be the minimum d-degree that ensures the\r\nexistence of a perfect matching
in an n-vertex k-uniform hypergraph. In general, it is\r\nan open question to
determine (even asymptotically) the values of md (k, n), but we are\r\nnonetheless
able to prove an analogue of the Cuckler–Kahn theorem, showing that if\r\nan n-vertex
k-uniform hypergraph G has minimum d-degree at least (1+γ )md (k, n)\r\n(for any
constantγ > 0), then the number of perfect matchings in G is controlled by\r\nan
entropy-like parameter of G. This strengthens cruder estimates arising from work\r\nof
Kang–Kelly–Kühn–Osthus–Pfenninger and Pham–Sah–Sawhney–Simkin."
acknowledgement: We would like to thank the referees for a number of helpful comments
and suggestions, which have substantially improved the paper. Open access funding
provided by Institute of Science and Technology (IST Austria).
article_number: '5'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Matthew Alan
full_name: Kwan, Matthew Alan
id: 5fca0887-a1db-11eb-95d1-ca9d5e0453b3
last_name: Kwan
orcid: 0000-0002-4003-7567
- first_name: Roodabeh
full_name: Safavi Hemami, Roodabeh
id: 72ed2640-8972-11ed-ae7b-f9c81ec75154
last_name: Safavi Hemami
- first_name: Yiting
full_name: Wang, Yiting
id: 1917d194-076e-11ed-97cd-837255f88785
last_name: Wang
orcid: 0000-0002-2856-767X
citation:
ama: Kwan MA, Safavi Hemami R, Wang Y. Counting perfect matchings in Dirac hypergraphs.
Combinatorica. 2026;46. doi:10.1007/s00493-025-00194-8
apa: Kwan, M. A., Safavi Hemami, R., & Wang, Y. (2026). Counting perfect matchings
in Dirac hypergraphs. Combinatorica. Springer Nature. https://doi.org/10.1007/s00493-025-00194-8
chicago: Kwan, Matthew Alan, Roodabeh Safavi Hemami, and Yiting Wang. “Counting
Perfect Matchings in Dirac Hypergraphs.” Combinatorica. Springer Nature,
2026. https://doi.org/10.1007/s00493-025-00194-8.
ieee: M. A. Kwan, R. Safavi Hemami, and Y. Wang, “Counting perfect matchings in
Dirac hypergraphs,” Combinatorica, vol. 46. Springer Nature, 2026.
ista: Kwan MA, Safavi Hemami R, Wang Y. 2026. Counting perfect matchings in Dirac
hypergraphs. Combinatorica. 46, 5.
mla: Kwan, Matthew Alan, et al. “Counting Perfect Matchings in Dirac Hypergraphs.”
Combinatorica, vol. 46, 5, Springer Nature, 2026, doi:10.1007/s00493-025-00194-8.
short: M.A. Kwan, R. Safavi Hemami, Y. Wang, Combinatorica 46 (2026).
corr_author: '1'
date_created: 2026-02-08T23:02:49Z
date_published: 2026-02-01T00:00:00Z
date_updated: 2026-02-16T09:55:17Z
day: '01'
ddc:
- '510'
department:
- _id: MaKw
- _id: MoHe
doi: 10.1007/s00493-025-00194-8
external_id:
arxiv:
- '2408.09589'
file:
- access_level: open_access
checksum: 47b0031d90b0e6b9a843f422a1486089
content_type: application/pdf
creator: dernst
date_created: 2026-02-16T09:52:38Z
date_updated: 2026-02-16T09:52:38Z
file_id: '21228'
file_name: 2026_Combinatorica_Kwan.pdf
file_size: 539646
relation: main_file
success: 1
file_date_updated: 2026-02-16T09:52:38Z
has_accepted_license: '1'
intvolume: ' 46'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
publication: Combinatorica
publication_identifier:
eissn:
- 1439-6912
issn:
- 0209-9683
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Counting perfect matchings in Dirac hypergraphs
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 46
year: '2026'
...
---
OA_place: publisher
OA_type: diamond
PlanS_conform: '1'
_id: '21160'
abstract:
- lang: eng
text: "Context. AM Canum Venaticorum (AM CVn) stars are ultra-compact binary systems
composed of a white dwarf primary accreting from a hydrogen-deficient donor. They
play a crucial role in astrophysics as potential progenitors of Type Ia supernovae
and as laboratories for gravitational wave studies. However, their formation and
evolutionary history remain incomplete. Three formation channels have been discussed
in the literature: the white dwarf, He-star, and cataclysmic variable channels.\r\n\r\nAims.
The chemical composition of the accretor atmosphere reflects the material transferred
from the donor. In this work we took the first accurate measurements of the fundamental
parameters of the accreting white dwarf in ZTF J225237.05−051917.4, including
the abundances of key elements such as carbon, nitrogen, and silicon, by analysing
ultraviolet spectra obtained with the Hubble Space Telescope (HST). These measurements
provide new insight into the evolutionary history of the system and, together
with existing optical observations, establish it as a benchmark to develop our
pipeline, paving the way for its application to a larger sample of AM CVn systems.\r\n\r\nMethods.
We determined the binary parameters through photometric analysis and constrained
the atmospheric parameters of the white dwarf accretor, including its effective
temperature, surface gravity, and chemical abundances, by fitting the HST ultraviolet
spectrum with synthetic spectral models. We then inferred the system’s formation
channel by comparing the results with theoretical evolutionary models.\r\n\r\nResults.
According to our measurements, the accretor’s effective temperature (Teff) is
23 300 ± 600 K and the surface gravity (log g) is 8.4 ± 0.3, which imply an accretor
mass (MWD) of 0.86 ± 0.16 M⊙. We find a high nitrogen-to-carbon abundance ratio
by mass of > 153.\r\n\r\nConclusions. The accretor is significantly hotter than
previous estimates based on simplified blackbody fits to the spectral energy distribution,
underscoring the importance of detailed spectral modelling for accurately determining
system parameters. Our results show that ultraviolet spectroscopy is well suited
to constraining the formation channels of AM CVn systems. Of the three proposed
formation channels, the He-star channel can be excluded given the high nitrogen-to-carbon
ratio. Our results are consistent with both the white dwarf and cataclysmic variable
channels."
acknowledgement: "We thank Lars Bildsten for valuable insights and discussions. We
acknowledge with thanks the variable star observations from the\r\nAAVSO International
Database contributed by observers worldwide and used in this research. We thank
the members of the Spanish Observers of Supernovae\r\n(ObSN) group for their valuable
photometric contributions. This research was\r\nsupported by Deutsche Forschungsgemeinschaft
(DFG, German Research Foundation) under Germany’s Excellence Strategy – EXC 2121
“Quantum Universe”\r\n– 390833306. Co-funded by the European Union (ERC, CompactBINARIES,\r\n101078773).
Views and opinions expressed are however those of the author(s)\r\nonly and do not
necessarily reflect those of the European Union or the European Research Council.
Neither the European Union nor the granting authority\r\ncan be held responsible
for them. DB acknowledges support from the São Paulo\r\nResearch Foundation (FAPESP),
Brazil, Process Numbers #2024/03736-2 and\r\n#2025/00817-4. MRS is supported by
Fondecyt (grant 1221059). MJG acknowledges support from the European Research Council
through ERC Advanced\r\nGrant No. 101054731, from the National Aeronautics and Space
Administration under grants 80NSSC24K0436, 80NSSC22K0479, and 80NSSC24K0380,\r\nand
from the National Science Foundation under grant AST-2205736. PJG\r\nis supported
by NRF SARChI grant 111692. PR-G acknowledges support by\r\nthe Agencia Estatal
de Investigación del Ministerio de Ciencia e Innovación\r\n(MCIN/AEI) and the European
Regional Development Fund (ERDF) under grant\r\nPID2021–124879NB–I00. DS is supported
by the UK Science and Technology Facilities Council (STFC, grant numbers ST/T007184/1,
ST/T003103/1,\r\nand ST/T000406/1). OT acknowledges Proyectos Internos USM 2025,
PI-LII2025-03. GT was supported by grants IN109723 from the Programa de Apoyo a\r\nProyectos
de Investigación e Innovación Tecnológica (PAPIIT). This project has\r\nreceived
funding from the European Research Council (ERC) under the European Union’s Horizon
2020 research and innovation programme (Grant agreement No. 101020057)."
article_number: A14
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: W.
full_name: Yu, W.
last_name: Yu
- first_name: A. F.
full_name: Pala, A. F.
last_name: Pala
- first_name: T.
full_name: Kupfer, T.
last_name: Kupfer
- first_name: B. T.
full_name: Gänsicke, B. T.
last_name: Gänsicke
- first_name: D.
full_name: Koester, D.
last_name: Koester
- first_name: D.
full_name: Belloni, D.
last_name: Belloni
- first_name: T. L.S.
full_name: Wong, T. L.S.
last_name: Wong
- first_name: M. R.
full_name: Schreiber, M. R.
last_name: Schreiber
- first_name: Joannes C
full_name: van Roestel, Joannes C
id: 4d122fc8-6083-11f0-87a5-97d68b860333
last_name: van Roestel
- first_name: A. J.
full_name: Brown, A. J.
last_name: Brown
- first_name: E. O.
full_name: Waagen, E. O.
last_name: Waagen
- first_name: J. L.
full_name: González-Carballo, J. L.
last_name: González-Carballo
- first_name: S.
full_name: Bednarz, S.
last_name: Bednarz
- first_name: K.
full_name: Bernacki, K.
last_name: Bernacki
- first_name: D.
full_name: De Martino, D.
last_name: De Martino
- first_name: E.
full_name: Fernández Mañanes, E.
last_name: Fernández Mañanes
- first_name: R.
full_name: González Farfán, R.
last_name: González Farfán
- first_name: M. J.
full_name: Green, M. J.
last_name: Green
- first_name: P. J.
full_name: Groot, P. J.
last_name: Groot
- first_name: F. J.
full_name: Hambsch, F. J.
last_name: Hambsch
- first_name: C.
full_name: Knigge, C.
last_name: Knigge
- first_name: J. L.
full_name: Martin-Velasco, J. L.
last_name: Martin-Velasco
- first_name: M.
full_name: Morales-Aimar, M.
last_name: Morales-Aimar
- first_name: G.
full_name: Myers, G.
last_name: Myers
- first_name: R.
full_name: Naves Nogues, R.
last_name: Naves Nogues
- first_name: R.
full_name: Poggiani, R.
last_name: Poggiani
- first_name: A.
full_name: Popowicz, A.
last_name: Popowicz
- first_name: G.
full_name: Ramsay, G.
last_name: Ramsay
- first_name: E.
full_name: Reina-Lorenz, E.
last_name: Reina-Lorenz
- first_name: P.
full_name: Rodríguez-Gil, P.
last_name: Rodríguez-Gil
- first_name: J. L.
full_name: Salto-González, J. L.
last_name: Salto-González
- first_name: E. M.
full_name: Sion, E. M.
last_name: Sion
- first_name: D.
full_name: Steeghs, D.
last_name: Steeghs
- first_name: P.
full_name: Szkody, P.
last_name: Szkody
- first_name: O.
full_name: Toloza, O.
last_name: Toloza
- first_name: G.
full_name: Tovmassian, G.
last_name: Tovmassian
citation:
ama: 'Yu W, Pala AF, Kupfer T, et al. The evolutionary history of ultra-compact
accreting binaries: I. Chemical abundances and the formation channel of the eclipsing
AM CVn system ZTF J225237.05-051917.4 from HST spectroscopy. Astronomy and
Astrophysics. 2026;706. doi:10.1051/0004-6361/202557568'
apa: 'Yu, W., Pala, A. F., Kupfer, T., Gänsicke, B. T., Koester, D., Belloni, D.,
… Tovmassian, G. (2026). The evolutionary history of ultra-compact accreting binaries:
I. Chemical abundances and the formation channel of the eclipsing AM CVn system
ZTF J225237.05-051917.4 from HST spectroscopy. Astronomy and Astrophysics.
EDP Sciences. https://doi.org/10.1051/0004-6361/202557568'
chicago: 'Yu, W., A. F. Pala, T. Kupfer, B. T. Gänsicke, D. Koester, D. Belloni,
T. L.S. Wong, et al. “The Evolutionary History of Ultra-Compact Accreting Binaries:
I. Chemical Abundances and the Formation Channel of the Eclipsing AM CVn System
ZTF J225237.05-051917.4 from HST Spectroscopy.” Astronomy and Astrophysics.
EDP Sciences, 2026. https://doi.org/10.1051/0004-6361/202557568.'
ieee: 'W. Yu et al., “The evolutionary history of ultra-compact accreting
binaries: I. Chemical abundances and the formation channel of the eclipsing AM
CVn system ZTF J225237.05-051917.4 from HST spectroscopy,” Astronomy and Astrophysics,
vol. 706. EDP Sciences, 2026.'
ista: 'Yu W, Pala AF, Kupfer T, Gänsicke BT, Koester D, Belloni D, Wong TLS, Schreiber
MR, van Roestel JC, Brown AJ, Waagen EO, González-Carballo JL, Bednarz S, Bernacki
K, De Martino D, Fernández Mañanes E, González Farfán R, Green MJ, Groot PJ, Hambsch
FJ, Knigge C, Martin-Velasco JL, Morales-Aimar M, Myers G, Naves Nogues R, Poggiani
R, Popowicz A, Ramsay G, Reina-Lorenz E, Rodríguez-Gil P, Salto-González JL, Sion
EM, Steeghs D, Szkody P, Toloza O, Tovmassian G. 2026. The evolutionary history
of ultra-compact accreting binaries: I. Chemical abundances and the formation
channel of the eclipsing AM CVn system ZTF J225237.05-051917.4 from HST spectroscopy.
Astronomy and Astrophysics. 706, A14.'
mla: 'Yu, W., et al. “The Evolutionary History of Ultra-Compact Accreting Binaries:
I. Chemical Abundances and the Formation Channel of the Eclipsing AM CVn System
ZTF J225237.05-051917.4 from HST Spectroscopy.” Astronomy and Astrophysics,
vol. 706, A14, EDP Sciences, 2026, doi:10.1051/0004-6361/202557568.'
short: W. Yu, A.F. Pala, T. Kupfer, B.T. Gänsicke, D. Koester, D. Belloni, T.L.S.
Wong, M.R. Schreiber, J.C. van Roestel, A.J. Brown, E.O. Waagen, J.L. González-Carballo,
S. Bednarz, K. Bernacki, D. De Martino, E. Fernández Mañanes, R. González Farfán,
M.J. Green, P.J. Groot, F.J. Hambsch, C. Knigge, J.L. Martin-Velasco, M. Morales-Aimar,
G. Myers, R. Naves Nogues, R. Poggiani, A. Popowicz, G. Ramsay, E. Reina-Lorenz,
P. Rodríguez-Gil, J.L. Salto-González, E.M. Sion, D. Steeghs, P. Szkody, O. Toloza,
G. Tovmassian, Astronomy and Astrophysics 706 (2026).
date_created: 2026-02-08T23:02:49Z
date_published: 2026-02-01T00:00:00Z
date_updated: 2026-02-16T09:36:24Z
day: '01'
ddc:
- '520'
department:
- _id: IlCa
doi: 10.1051/0004-6361/202557568
external_id:
arxiv:
- '2512.04147'
file:
- access_level: open_access
checksum: 2faec710fd04f927aa43deb57e35c9b2
content_type: application/pdf
creator: dernst
date_created: 2026-02-16T09:33:56Z
date_updated: 2026-02-16T09:33:56Z
file_id: '21227'
file_name: 2026_AstronomyAstrophysics_Yu.pdf
file_size: 4020466
relation: main_file
success: 1
file_date_updated: 2026-02-16T09:33:56Z
has_accepted_license: '1'
intvolume: ' 706'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
publication: Astronomy and Astrophysics
publication_identifier:
eissn:
- 1432-0746
issn:
- 0004-6361
publication_status: published
publisher: EDP Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The evolutionary history of ultra-compact accreting binaries: I. Chemical
abundances and the formation channel of the eclipsing AM CVn system ZTF J225237.05-051917.4
from HST spectroscopy'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 706
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21161'
abstract:
- lang: eng
text: In many species, sex-biased expression is widespread and thought to contribute
to sexual dimorphism. While bulk RNA-sequencing has been instrumental in identifying
strongly sex-biased genes, it lacks resolution to assess variation across cell-types
and tissue compartments. Using single-nucleus expression data from the Fly Cell
Atlas, we investigate sex differences in adult Drosophila melanogaster. We find
that differences in cell-type composition between the sexes are not a major source
of sex-bias, as for the vast majority of genes, the degree of sex-bias is similar
regardless of whether sex differences in cell-type composition are controlled
for or not. Our analysis confirms a deficit of X-linked male-biased genes in the
body’s somatic tissues that is widespread across cell-types. We also find the
excess of X-linked female-biased genes to be associated with nervous system cells
in the head but with epithelial cells in the body’s somatic tissues, showing that
single-nucleus data crucially resolves sex-bias at the cell-type level. We investigate
dosage compensation (DC) across 15 tissues and 17 cell-types. We observe that
it varies throughout the body. Surprisingly, we observe a lack of DC in a cluster
of main cells within the male accessory glands. This result highlights the importance
of understanding context-dependent DC.
acknowledged_ssus:
- _id: ScienComp
- _id: Bio
acknowledgement: This work was partly funded by an Austrian Science Foundation FWF
ESPRIT fellowship (10.55776/ESP6331524) to C.B. We would like to thank the Vicoso
group for their invaluable input and discussions throughout this work. We thank
Filip Ruzicka for his insightful comments on the manuscript. All computational resources
were provided by the Scientific Computing Unit at ISTA. This research was also supported
through resources provided by the Imaging & Optics Facility (IOF) at ISTA.
article_number: '20252471'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Carolina
full_name: De Castro Barbosa Rodrigues Barata, Carolina
id: 20565186-803f-11ed-ab7e-96a4ff7694ef
last_name: De Castro Barbosa Rodrigues Barata
orcid: 0000-0003-1945-2245
- first_name: Beatriz
full_name: Vicoso, Beatriz
id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
last_name: Vicoso
orcid: 0000-0002-4579-8306
citation:
ama: de Castro Barbosa Rodrigues Barata C, Vicoso B. Single-nucleus resolution of
sex-biased expression and dosage compensation in Drosophila melanogaster. Proceedings
of the Royal Society B Biological Sciences. 2026;293(2063). doi:10.1098/rspb.2025.2471
apa: de Castro Barbosa Rodrigues Barata, C., & Vicoso, B. (2026). Single-nucleus
resolution of sex-biased expression and dosage compensation in Drosophila melanogaster.
Proceedings of the Royal Society B Biological Sciences. Royal Society of
London. https://doi.org/10.1098/rspb.2025.2471
chicago: Castro Barbosa Rodrigues Barata, Carolina de, and Beatriz Vicoso. “Single-Nucleus
Resolution of Sex-Biased Expression and Dosage Compensation in Drosophila Melanogaster.”
Proceedings of the Royal Society B Biological Sciences. Royal Society of
London, 2026. https://doi.org/10.1098/rspb.2025.2471.
ieee: C. de Castro Barbosa Rodrigues Barata and B. Vicoso, “Single-nucleus resolution
of sex-biased expression and dosage compensation in Drosophila melanogaster,”
Proceedings of the Royal Society B Biological Sciences, vol. 293, no. 2063.
Royal Society of London, 2026.
ista: de Castro Barbosa Rodrigues Barata C, Vicoso B. 2026. Single-nucleus resolution
of sex-biased expression and dosage compensation in Drosophila melanogaster. Proceedings
of the Royal Society B Biological Sciences. 293(2063), 20252471.
mla: de Castro Barbosa Rodrigues Barata, Carolina, and Beatriz Vicoso. “Single-Nucleus
Resolution of Sex-Biased Expression and Dosage Compensation in Drosophila Melanogaster.”
Proceedings of the Royal Society B Biological Sciences, vol. 293, no. 2063,
20252471, Royal Society of London, 2026, doi:10.1098/rspb.2025.2471.
short: C. de Castro Barbosa Rodrigues Barata, B. Vicoso, Proceedings of the Royal
Society B Biological Sciences 293 (2026).
corr_author: '1'
date_created: 2026-02-08T23:02:49Z
date_published: 2026-01-28T00:00:00Z
date_updated: 2026-02-16T09:27:33Z
day: '28'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1098/rspb.2025.2471
external_id:
pmid:
- '41592777'
file:
- access_level: open_access
checksum: d76afebca0a6f112df0146ae2d929f36
content_type: application/pdf
creator: dernst
date_created: 2026-02-16T09:26:02Z
date_updated: 2026-02-16T09:26:02Z
file_id: '21226'
file_name: 2026_RoyalSocPubProceedingsB_Barata.pdf
file_size: 2230841
relation: main_file
success: 1
file_date_updated: 2026-02-16T09:26:02Z
has_accepted_license: '1'
intvolume: ' 293'
issue: '2063'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 90ef7108-16d5-11f0-9cad-e6e116913473
grant_number: ESP 6331524
name: Does genetic drift set a limit on the adaptive evolution of sex-biased expression?
publication: Proceedings of the Royal Society B Biological Sciences
publication_identifier:
eissn:
- 1471-2954
publication_status: published
publisher: Royal Society of London
quality_controlled: '1'
scopus_import: '1'
status: public
title: Single-nucleus resolution of sex-biased expression and dosage compensation
in Drosophila melanogaster
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 293
year: '2026'
...
---
_id: '21164'
abstract:
- lang: eng
text: 'Global emission inventories often fail to capture the complexities of vehicular
pollution in regions with unique fuel mixes, such as Brazil’s extensive biofuel
use, leading to significant uncertainties in atmospheric modeling. This study
presents a century-long (1960–2100) bottom-up vehicular emission inventory for
Brazil, leveraging locally derived emission factors. Our estimates reveal substantial
discrepancies in magnitude, timing, and speciation of non-CO2 pollutants (CO,
NMHC, PM2.5) compared to leading global inventories (EDGAR, CEDS, CAMS), highlighting
critical inaccuracies in widely used data sets. More critically, future projections
under Shared Socioeconomic Pathways (SSPs) uncover a novel positive feedback mechanism:
rising temperatures significantly enhance vehicular evaporative nonmethane hydrocarbon
(NMHC) emissions. This temperature-dependent increase and subsequent NMHC oxidation
to CO2 suggest an overlooked pathway that could amplify climate warming and air
pollution globally, particularly after a breakpoint around 2050 (p < 0.05). While
historical emissions peaked in the 1990s–2000s, nonexhaust PM becomes increasingly
important. Air quality simulations using our inventory in the MUSICA model show
good regional PM2.5 agreement but highlight challenges in resolving local primary
pollutant peaks. This comprehensive inventory provides crucial data for Brazil
and uncovers globally relevant climate–chemistry interactions, urging a re-evaluation
of regional specificities in global emission assessments.'
acknowledgement: Part of this material is based upon work supported by the NSF National
Center for Atmospheric Research, which is a major facility sponsored by the National
Science Foundation under Cooperative Agreement No. 1852977. Casallas was supported
by the European Union’s Horizon 2020 research and innovation program under the Marie
Skłodowska-Curie grant agreement No. 101034413. E. D. Freitas thanks the support
provided by the National Council for Scientific and Technological Development (CNPq,
Process number 313210/2022–5). Silva gratefully acknowledges the financial support
from the National Council for Scientific and Technological Development (CNPq), process
number 140512/2021–7. P. Lichtig was supported by base funding from the National
Commission for Atomic Energy (CNEA, Arg.) and by NSF NCAR. R.Y. Ynoue thanks the
support provided by the National Council for Scientific and Technological Development
(CNPq, Process number 406728/2022–4). M. A. Franco thanks the support provided by
the National Council for Scientific and Technological Development (CNPq, Process
number 407752/2023–4). G. M. Pereira thanks the support by the Fundação de Amparo
à Pesquisa do Estado de São Paulo (FAPESP; Process numbers 2018/07848–9, 2016/18438–0,
and 2019/01316–80) and Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
(CAPES; Process number 88887.103225/2025–00). M.F. Andrade thanks the support by
FAPESP (Process number 2016/18438–0) and CNPQ (Klimapolis INCT).
article_number: 5c08400
article_processing_charge: No
article_type: original
author:
- first_name: Sergio
full_name: Ibarra-Espinosa, Sergio
last_name: Ibarra-Espinosa
- first_name: Edmilson
full_name: Dias de Freitas, Edmilson
last_name: Dias de Freitas
- first_name: Benjamin
full_name: Gaubert, Benjamin
last_name: Gaubert
- first_name: Pablo
full_name: Lichtig, Pablo
last_name: Lichtig
- first_name: Karl
full_name: Ropkins, Karl
last_name: Ropkins
- first_name: Iara
full_name: da Silva, Iara
last_name: da Silva
- first_name: Guilherme
full_name: Martins Pereira, Guilherme
last_name: Martins Pereira
- first_name: Daniel
full_name: Schuch, Daniel
last_name: Schuch
- first_name: Janaina
full_name: Nascimento, Janaina
last_name: Nascimento
- first_name: Leonardo
full_name: Hoinaski, Leonardo
last_name: Hoinaski
- first_name: Leila Droprinchinski
full_name: Martins, Leila Droprinchinski
last_name: Martins
- first_name: Mario
full_name: Gavidia-Calderón, Mario
last_name: Gavidia-Calderón
- first_name: Angel
full_name: Vara-Vela, Angel
last_name: Vara-Vela
- first_name: Taciana
full_name: Toledo de Almeida Albuquerque, Taciana
last_name: Toledo de Almeida Albuquerque
- first_name: Rita Yuri
full_name: Ynoue, Rita Yuri
last_name: Ynoue
- first_name: Sebastian
full_name: Diez, Sebastian
last_name: Diez
- first_name: Zamir
full_name: Mera, Zamir
last_name: Mera
- first_name: Alejandro
full_name: Casallas Garcia, Alejandro
id: 92081129-2d75-11ef-a48d-b04dd7a2385a
last_name: Casallas Garcia
orcid: 0000-0002-1988-5035
- first_name: Fidel
full_name: Vallejo, Fidel
last_name: Vallejo
- first_name: Valeria
full_name: Diaz, Valeria
last_name: Diaz
- first_name: Rizzieri
full_name: Pedruzzi, Rizzieri
last_name: Pedruzzi
- first_name: Rosana
full_name: Abrutzky, Rosana
last_name: Abrutzky
- first_name: Marco A.
full_name: Franco, Marco A.
last_name: Franco
- first_name: Nicolas
full_name: Huneeus, Nicolas
last_name: Huneeus
- first_name: Hector
full_name: Jorquera, Hector
last_name: Jorquera
- first_name: Luis Carlos
full_name: Belalcázar-Cerón, Luis Carlos
last_name: Belalcázar-Cerón
- first_name: Néstor Y.
full_name: Rojas, Néstor Y.
last_name: Rojas
- first_name: Maria
full_name: de Fatima Andrade, Maria
last_name: de Fatima Andrade
- first_name: Louisa
full_name: Emmons, Louisa
last_name: Emmons
- first_name: Guy
full_name: Brasseur, Guy
last_name: Brasseur
citation:
ama: 'Ibarra-Espinosa S, Dias de Freitas E, Gaubert B, et al. A century of vehicular
emissions in Brazil: Unveiling the impacts of unique fuel mix on air quality.
Environmental Science & Technology. 2026. doi:10.1021/acs.est.5c08400'
apa: 'Ibarra-Espinosa, S., Dias de Freitas, E., Gaubert, B., Lichtig, P., Ropkins,
K., da Silva, I., … Brasseur, G. (2026). A century of vehicular emissions in Brazil:
Unveiling the impacts of unique fuel mix on air quality. Environmental Science
& Technology. American Chemical Society. https://doi.org/10.1021/acs.est.5c08400'
chicago: 'Ibarra-Espinosa, Sergio, Edmilson Dias de Freitas, Benjamin Gaubert, Pablo
Lichtig, Karl Ropkins, Iara da Silva, Guilherme Martins Pereira, et al. “A Century
of Vehicular Emissions in Brazil: Unveiling the Impacts of Unique Fuel Mix on
Air Quality.” Environmental Science & Technology. American Chemical
Society, 2026. https://doi.org/10.1021/acs.est.5c08400.'
ieee: 'S. Ibarra-Espinosa et al., “A century of vehicular emissions in Brazil:
Unveiling the impacts of unique fuel mix on air quality,” Environmental Science
& Technology. American Chemical Society, 2026.'
ista: 'Ibarra-Espinosa S, Dias de Freitas E, Gaubert B, Lichtig P, Ropkins K, da
Silva I, Martins Pereira G, Schuch D, Nascimento J, Hoinaski L, Martins LD, Gavidia-Calderón
M, Vara-Vela A, Toledo de Almeida Albuquerque T, Ynoue RY, Diez S, Mera Z, Casallas
Garcia A, Vallejo F, Diaz V, Pedruzzi R, Abrutzky R, Franco MA, Huneeus N, Jorquera
H, Belalcázar-Cerón LC, Rojas NY, de Fatima Andrade M, Emmons L, Brasseur G. 2026.
A century of vehicular emissions in Brazil: Unveiling the impacts of unique fuel
mix on air quality. Environmental Science & Technology., 5c08400.'
mla: 'Ibarra-Espinosa, Sergio, et al. “A Century of Vehicular Emissions in Brazil:
Unveiling the Impacts of Unique Fuel Mix on Air Quality.” Environmental Science
& Technology, 5c08400, American Chemical Society, 2026, doi:10.1021/acs.est.5c08400.'
short: S. Ibarra-Espinosa, E. Dias de Freitas, B. Gaubert, P. Lichtig, K. Ropkins,
I. da Silva, G. Martins Pereira, D. Schuch, J. Nascimento, L. Hoinaski, L.D. Martins,
M. Gavidia-Calderón, A. Vara-Vela, T. Toledo de Almeida Albuquerque, R.Y. Ynoue,
S. Diez, Z. Mera, A. Casallas Garcia, F. Vallejo, V. Diaz, R. Pedruzzi, R. Abrutzky,
M.A. Franco, N. Huneeus, H. Jorquera, L.C. Belalcázar-Cerón, N.Y. Rojas, M. de
Fatima Andrade, L. Emmons, G. Brasseur, Environmental Science & Technology
(2026).
date_created: 2026-02-09T06:54:10Z
date_published: 2026-02-04T00:00:00Z
date_updated: 2026-02-16T10:33:07Z
day: '04'
ddc:
- '550'
department:
- _id: CaMu
doi: 10.1021/acs.est.5c08400
ec_funded: 1
external_id:
pmid:
- '41636708'
has_accepted_license: '1'
language:
- iso: eng
month: '02'
oa_version: None
pmid: 1
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
call_identifier: H2020
grant_number: '101034413'
name: 'IST-BRIDGE: International postdoctoral program'
publication: Environmental Science & Technology
publication_identifier:
eissn:
- 1520-5851
issn:
- 0013-936X
publication_status: epub_ahead
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'A century of vehicular emissions in Brazil: Unveiling the impacts of unique
fuel mix on air quality'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: repository
OA_type: free access
_id: '21174'
abstract:
- lang: eng
text: UTe2 exhibits the remarkable phenomenon of re-entrant superconductivity, whereby
the zero-resistance state reappears above 40 tesla after being suppressed with
a field of around 10 tesla. One potential pairing mechanism, invoked in the related
re-entrant superconductors UCoGe and URhGe, involves transverse fluctuations of
a ferromagnetic order parameter. However, the requisite ferromagnetic order -
present in both UCoGe and URhGe - is absent in UTe2, and magnetization measurements
show no sign of strong fluctuations. Here, we measure the magnetotropic susceptibility
of UTe2 across two field-angle planes. This quantity is sensitive to the magnetic
susceptibility in a direction transverse to the applied magnetic field - a quantity
that is not accessed in conventional magnetization measurements. We observe a
very large decrease in the magnetotropic susceptibility over a broad range of
field orientations, indicating a large increase in the transverse magnetic susceptibility.
The three superconducting phases of UTe2, including the high-field re-entrant
phase, surround this region of enhanced susceptibility in the field-angle phase
diagram. The strongest transverse susceptibility is found near the critical end
point of the high-field metamagnetic transition, suggesting that quantum critical
fluctuations of a field-induced magnetic order parameter may be responsible for
the large transverse susceptibility, and may provide a pairing mechanism for field-induced
superconductivity in UTe2.
acknowledged_ssus:
- _id: NanoFab
acknowledgement: Thanks to Salvatore Bagiante, Evgeniia Volobueva, Lubuna Shafeek,
Ali Bangura and Zoltan Kollo.
article_processing_charge: Yes
author:
- first_name: Kimberly A
full_name: Modic, Kimberly A
id: 13C26AC0-EB69-11E9-87C6-5F3BE6697425
last_name: Modic
orcid: 0000-0001-9760-3147
citation:
ama: Modic KA. Research data for “Giant transverse magnetic fluctuations at the
edge of re-entrant superconductivity in UTe2.” 2026. doi:10.15479/AT-ISTA-21174
apa: Modic, K. A. (2026). Research data for “Giant transverse magnetic fluctuations
at the edge of re-entrant superconductivity in UTe2.” Institute of Science and
Technology Austria. https://doi.org/10.15479/AT-ISTA-21174
chicago: Modic, Kimberly A. “Research Data for ‘Giant Transverse Magnetic Fluctuations
at the Edge of Re-Entrant Superconductivity in UTe2.’” Institute of Science and
Technology Austria, 2026. https://doi.org/10.15479/AT-ISTA-21174.
ieee: K. A. Modic, “Research data for ‘Giant transverse magnetic fluctuations at
the edge of re-entrant superconductivity in UTe2.’” Institute of Science and Technology
Austria, 2026.
ista: Modic KA. 2026. Research data for ‘Giant transverse magnetic fluctuations
at the edge of re-entrant superconductivity in UTe2’, Institute of Science and
Technology Austria, 10.15479/AT-ISTA-21174.
mla: Modic, Kimberly A. Research Data for “Giant Transverse Magnetic Fluctuations
at the Edge of Re-Entrant Superconductivity in UTe2.” Institute of Science
and Technology Austria, 2026, doi:10.15479/AT-ISTA-21174.
short: K.A. Modic, (2026).
contributor:
- contributor_type: project_member
first_name: Valeska
id: 467ed36b-dc96-11ea-b7c8-b043a380b282
last_name: Zambra
orcid: 0000-0002-8806-5719
corr_author: '1'
date_created: 2026-02-09T12:04:20Z
date_published: 2026-02-19T00:00:00Z
date_updated: 2026-02-19T10:13:30Z
day: '19'
ddc:
- '530'
department:
- _id: KiMo
doi: 10.15479/AT-ISTA-21174
file:
- access_level: open_access
checksum: 53157d908fba663275c2b8dc6ee84fdb
content_type: text/plain
creator: kmodic
date_created: 2026-02-19T07:38:15Z
date_updated: 2026-02-19T07:38:15Z
file_id: '21332'
file_name: README.txt
file_size: 1347
relation: main_file
success: 1
- access_level: open_access
checksum: b2c8ca5620ee9c181a42082068d3d73c
content_type: application/zip
creator: kmodic
date_created: 2026-02-19T07:39:03Z
date_updated: 2026-02-19T07:39:03Z
file_id: '21333'
file_name: processed_data_bc_plane_Fig2d.zip
file_size: 534853
relation: main_file
success: 1
- access_level: open_access
checksum: 976bf113da4b1133313f0b292e71289f
content_type: application/zip
creator: kmodic
date_created: 2026-02-19T07:39:07Z
date_updated: 2026-02-19T07:39:07Z
file_id: '21334'
file_name: processed_data_ac_plane_Fig2c.zip
file_size: 427144
relation: main_file
success: 1
file_date_updated: 2026-02-19T07:39:07Z
has_accepted_license: '1'
keyword:
- transverse magnetic susceptibility
- magnetotropic
- superconductivity
- magnetic fluctuations
month: '02'
oa: 1
oa_version: Published Version
project:
- _id: bd968c70-d553-11ed-ba76-cde40b0aba64
grant_number: '101078696'
name: Gaining leverage with spin liquids and superconductors
publisher: Institute of Science and Technology Austria
related_material:
link:
- relation: preprint
url: https://arxiv.org/pdf/2506.08984
status: public
title: Research data for "Giant transverse magnetic fluctuations at the edge of re-entrant
superconductivity in UTe2"
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: research_data
user_id: 68b8ca59-c5b3-11ee-8790-cd641c68093d
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '21212'
abstract:
- lang: eng
text: "Malignant glioma is incurable. Using a mouse genetic mosaic system to generate
sporadic Trp53,Nf1-null OPCs, we previously identified oligodendrocyte precursor
cell (OPC) as a cell-of-origin of glioma. Here, we report that pre-malignant Trp53,Nf1-null
OPCs outcompete wildtype counterparts during their expansion. Blocking competition
by mutating/strengthening wildtype OPCs impeded both pre-malignant progression
and malignant expansion of glioma.\r\n\r\n“In-tissue” phosphoproteomic profiling
revealed an enrichment of phosphopeptides related to RNA splicing and protein
translation at the peak of cell competition, suggesting that competitiveness may
stem from unique protein species. Among candidates was mTORC1, whose pharmacological
inhibition or genetic disruption resulted in a loss of competitiveness in our
mouse model. Finally, analysis of patient biopsies and interrogating the role
of individual gliomagenic mutations in OPC competition supported its relevance
in human gliomas. Together, these findings identified the driving role of competitive
interactions among OPCs in gliomagenesis, and suggest unconventional therapeutic
strategies to target this process."
acknowledgement: "We thank Dr. Wenjie Liu for providing critical feedback on the manuscript.
We also thank Dr.\r\nPat Pramoonjago at the Biorepository and Tissue Research Facility,
and Hope Davis at the\r\nvivarium for their assistance on the project. These Core
Facilities are supported by UVA Cancer\r\nCenter grant #P30-CA044579. We are grateful
to Dr. Jonathan A. Epstein for providing the\r\nNf1GRD/+ mouse strain (https://pubmed.ncbi.nlm.nih.gov/26460546/).
This work was partly\r\nsupported by the National Institute of Neurological Diseases
and Stroke R21 NS125479-01A1\r\n(H.Z.), American Cancer Society Institutional Research
Grant to the University of Virginia\r\n(Y.J.), the National Natural Science Foundation
of China #82072787 (M.Y.), the National\r\nCancer Institute U54 CA238114 (F.W.),
U01 CA284193 (K.M.N.), and U54 CA274499 (K.A.J.,\r\nM.F-S.), the National institute
of General Medical Sciences R35 GM133404 (M.F-S.), the Dr.\r\nMiriam and Sheldon
G. Adelson Medical Research Foundation (H.I.K., S.A.G.), the National\r\nCenter
for Advancing Translational Sciences KL2TR001882 (K.S.P.), Tower Cancer Career Development
Grant (K.S.P.), McKnight Neurobiology of Brain Disorders Grant (K.S.P.). The\r\ncontent
is solely the responsibility of the authors and does not necessarily represent the
official\r\nviews of the National Institutes of Health. Illustrations in this manuscript
were created with\r\nBioRender (BioRender.com)."
article_processing_charge: No
author:
- first_name: Ying
full_name: Jiang, Ying
last_name: Jiang
- first_name: Ryuhjin
full_name: Ahn, Ryuhjin
last_name: Ahn
- first_name: Arthur
full_name: Huang, Arthur
last_name: Huang
- first_name: Phillippe P.
full_name: Gonzalez, Phillippe P.
last_name: Gonzalez
- first_name: Jungeun
full_name: Kim, Jungeun
last_name: Kim
- first_name: Guoxin
full_name: Zhang, Guoxin
last_name: Zhang
- first_name: Zihao
full_name: Liu, Zihao
last_name: Liu
- first_name: Zhenqiang
full_name: He, Zhenqiang
last_name: He
- first_name: Lindsey
full_name: Dudley, Lindsey
last_name: Dudley
- first_name: Kunal S.
full_name: Patel, Kunal S.
last_name: Patel
- first_name: Godfrey A.
full_name: Dzhivhuho, Godfrey A.
last_name: Dzhivhuho
- first_name: Sam
full_name: Crowl, Sam
last_name: Crowl
- first_name: Piotr
full_name: Przanowski, Piotr
last_name: Przanowski
- first_name: Luisa Quesada
full_name: Camacho, Luisa Quesada
last_name: Camacho
- first_name: Sijie
full_name: Hao, Sijie
last_name: Hao
- first_name: Jianhao
full_name: Zeng, Jianhao
last_name: Zeng
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
- first_name: Mohammad
full_name: Fallahi-Sichani, Mohammad
last_name: Fallahi-Sichani
- first_name: Kevin A.
full_name: Janes, Kevin A.
last_name: Janes
- first_name: Kristen M.
full_name: Naegle, Kristen M.
last_name: Naegle
- first_name: Marie-Louise
full_name: Hammarskjold, Marie-Louise
last_name: Hammarskjold
- first_name: Steven A.
full_name: Goldman, Steven A.
last_name: Goldman
- first_name: Harley I.
full_name: Kornblum, Harley I.
last_name: Kornblum
- first_name: Maojin
full_name: Yao, Maojin
last_name: Yao
- first_name: Forest
full_name: White, Forest
last_name: White
- first_name: Hui
full_name: Zong, Hui
last_name: Zong
citation:
ama: Jiang Y, Ahn R, Huang A, et al. Critical role of cell competition in gliomagenesis.
bioRxiv. 2026. doi:10.64898/2026.01.15.699808
apa: Jiang, Y., Ahn, R., Huang, A., Gonzalez, P. P., Kim, J., Zhang, G., … Zong,
H. (2026). Critical role of cell competition in gliomagenesis. bioRxiv.
https://doi.org/10.64898/2026.01.15.699808
chicago: Jiang, Ying, Ryuhjin Ahn, Arthur Huang, Phillippe P. Gonzalez, Jungeun
Kim, Guoxin Zhang, Zihao Liu, et al. “Critical Role of Cell Competition in Gliomagenesis.”
BioRxiv, 2026. https://doi.org/10.64898/2026.01.15.699808.
ieee: Y. Jiang et al., “Critical role of cell competition in gliomagenesis,”
bioRxiv. 2026.
ista: Jiang Y, Ahn R, Huang A, Gonzalez PP, Kim J, Zhang G, Liu Z, He Z, Dudley
L, Patel KS, Dzhivhuho GA, Crowl S, Przanowski P, Camacho LQ, Hao S, Zeng J, Hippenmeyer
S, Fallahi-Sichani M, Janes KA, Naegle KM, Hammarskjold M-L, Goldman SA, Kornblum
HI, Yao M, White F, Zong H. 2026. Critical role of cell competition in gliomagenesis.
bioRxiv, 10.64898/2026.01.15.699808.
mla: Jiang, Ying, et al. “Critical Role of Cell Competition in Gliomagenesis.” BioRxiv,
2026, doi:10.64898/2026.01.15.699808.
short: Y. Jiang, R. Ahn, A. Huang, P.P. Gonzalez, J. Kim, G. Zhang, Z. Liu, Z. He,
L. Dudley, K.S. Patel, G.A. Dzhivhuho, S. Crowl, P. Przanowski, L.Q. Camacho,
S. Hao, J. Zeng, S. Hippenmeyer, M. Fallahi-Sichani, K.A. Janes, K.M. Naegle,
M.-L. Hammarskjold, S.A. Goldman, H.I. Kornblum, M. Yao, F. White, H. Zong, BioRxiv
(2026).
date_created: 2026-02-10T12:55:55Z
date_published: 2026-01-16T00:00:00Z
date_updated: 2026-02-16T10:12:42Z
day: '16'
ddc:
- '570'
department:
- _id: SiHi
doi: 10.64898/2026.01.15.699808
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.64898/2026.01.15.699808
month: '01'
oa: 1
oa_version: Preprint
publication: bioRxiv
publication_status: published
status: public
title: Critical role of cell competition in gliomagenesis
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21217'
abstract:
- lang: eng
text: This study investigates the mechanisms driving clustered convection and the
breakdown of the Intertropical Convergence Zone (ITCZ) over the Western Pacific
Warm Pool using high‐resolution cloud‐resolving simulations and machine‐learning
sensitivity experiments. Results show that ITCZ breakdown episodes, marked by
spatially homogeneous convection and weakened meridional moisture gradients, are
triggered primarily by anomalous moisture advection linked to the equatorial Rossby‐wave
activity. While large‐scale moisture advection regulates the background convective
state strongly, it is the surface and low‐level meridional winds that dominate
transitions between clustered and random convection. Simulations demonstrate that
moisture alone can sustain convective clustering, but breakdown episodes are more
persistent and widespread when coupled with southerly meridional advection. These
findings confirm that wave‐driven advection acts as a regulatory mechanism, periodically
disrupting convective clustering and reshaping the meridional moisture gradient.
This modulation of organization by wave‐induced breakdown events is critical for
understanding tropical convection variability and its implications for the climate
system.
acknowledgement: This article is based on chapter 5 of the PhD thesis of A. Casallas.
The authors thank Graziano Giuliani for discussions on the boundary-condition experiments.
A. Casallas was supported by a PhD fellowship awarded by the Abdus Salam International
Centre for Theoretical Physics. A. Casallas also acknowledges support by the European
Union's Horizon 2020 research and innovation program under the Marie Skłodowska-Curie
grant agreement No 101034413. C. Muller acknowledges funding from the European Research
Council (ERC) under the European Union's Horizon 2020 research and innovation program
(Project CLUSTER, Grant Agreement No. 805041). The authors gratefully acknowledge
Daniel Hernández-Deckers, Lokahith Agasthya, Chris Holloway, and Paolina Cerlini
for their valuable feedback and insightful discussions. They are especially thankful
to Bety Pechacova for suggesting the use of SHAP to complement their analysis. They
also thank the two anonymous reviewers for their constructive comments, which improved
the quality and clarity of the article significantly. Open Access funding provided
by Institute of Science and Technology Austria/KEMÖ.
article_number: e70131
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Alejandro
full_name: Casallas Garcia, Alejandro
id: 92081129-2d75-11ef-a48d-b04dd7a2385a
last_name: Casallas Garcia
orcid: 0000-0002-1988-5035
- first_name: Adrian
full_name: Mark Tompkins, Adrian
last_name: Mark Tompkins
- first_name: Caroline J
full_name: Muller, Caroline J
id: f978ccb0-3f7f-11eb-b193-b0e2bd13182b
last_name: Muller
orcid: 0000-0001-5836-5350
citation:
ama: Casallas Garcia A, Mark Tompkins A, Muller CJ. Moisture and wind effects of
Rossby waves on Western Pacific Intertropical Convergence Zone breakdown events.
Quarterly Journal of the Royal Meteorological Society. 2026. doi:10.1002/qj.70131
apa: Casallas Garcia, A., Mark Tompkins, A., & Muller, C. J. (2026). Moisture
and wind effects of Rossby waves on Western Pacific Intertropical Convergence
Zone breakdown events. Quarterly Journal of the Royal Meteorological Society.
Wiley. https://doi.org/10.1002/qj.70131
chicago: Casallas Garcia, Alejandro, Adrian Mark Tompkins, and Caroline J Muller.
“Moisture and Wind Effects of Rossby Waves on Western Pacific Intertropical Convergence
Zone Breakdown Events.” Quarterly Journal of the Royal Meteorological Society.
Wiley, 2026. https://doi.org/10.1002/qj.70131.
ieee: A. Casallas Garcia, A. Mark Tompkins, and C. J. Muller, “Moisture and wind
effects of Rossby waves on Western Pacific Intertropical Convergence Zone breakdown
events,” Quarterly Journal of the Royal Meteorological Society. Wiley,
2026.
ista: Casallas Garcia A, Mark Tompkins A, Muller CJ. 2026. Moisture and wind effects
of Rossby waves on Western Pacific Intertropical Convergence Zone breakdown events.
Quarterly Journal of the Royal Meteorological Society., e70131.
mla: Casallas Garcia, Alejandro, et al. “Moisture and Wind Effects of Rossby Waves
on Western Pacific Intertropical Convergence Zone Breakdown Events.” Quarterly
Journal of the Royal Meteorological Society, e70131, Wiley, 2026, doi:10.1002/qj.70131.
short: A. Casallas Garcia, A. Mark Tompkins, C.J. Muller, Quarterly Journal of the
Royal Meteorological Society (2026).
corr_author: '1'
date_created: 2026-02-12T10:13:02Z
date_published: 2026-02-12T00:00:00Z
date_updated: 2026-02-16T10:19:52Z
day: '12'
ddc:
- '550'
department:
- _id: CaMu
doi: 10.1002/qj.70131
ec_funded: 1
has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/4.0/
main_file_link:
- open_access: '1'
url: https://doi.org/10.1002/qj.70131
month: '02'
oa: 1
oa_version: Published Version
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
call_identifier: H2020
grant_number: '101034413'
name: 'IST-BRIDGE: International postdoctoral program'
- _id: 629205d8-2b32-11ec-9570-e1356ff73576
call_identifier: H2020
grant_number: '805041'
name: Organization of CLoUdS, and implications of Tropical cyclones and for the
Energetics of the tropics, in current and waRming climate
publication: Quarterly Journal of the Royal Meteorological Society
publication_identifier:
eissn:
- 1477-870X
issn:
- 0035-9009
publication_status: epub_ahead
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Moisture and wind effects of Rossby waves on Western Pacific Intertropical
Convergence Zone breakdown events
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '21230'
abstract:
- lang: eng
text: Asteroseismology is the study of the interior physics and structure of stars
using their pulsations. It is applicable to stars across the Hertzsprung–Russell
(HR) diagram and a powerful technique not only to measure masses, radii, and ages
but also directly constrain interior rotation, chemical mixing, and magnetism.
This is because a star's self-excited pulsation modes are sensitive to its structure.
Asteroseismology generally requires long-duration and high-precision time-series
data. The method of forward asteroseismic modeling, which is the statistical comparison
of observed pulsation mode frequencies to theoretically predicted pulsation frequencies
calculated from a grid of models, provides precise constraints for calibrating
various transport phenomena. In this introduction to asteroseismology, we provide
an overview of its principles, and the typical data sets and methodologies used
to constrain stellar interiors. Finally, we present key highlights of asteroseismic
results from across the HR diagram, and conclude with ongoing challenges and future
prospects for this ever-expanding field within stellar astrophysics.
article_processing_charge: No
arxiv: 1
author:
- first_name: Dominic M.
full_name: Bowman, Dominic M.
last_name: Bowman
- first_name: Lisa Annabelle
full_name: Bugnet, Lisa Annabelle
id: d9edb345-f866-11ec-9b37-d119b5234501
last_name: Bugnet
orcid: 0000-0003-0142-4000
citation:
ama: 'Bowman DM, Bugnet LA. Asteroseismology. In: Mandel I, ed. Encyclopedia
of Astrophysics. Vol 2. Elsevier; 2026:133-153. doi:10.1016/b978-0-443-21439-4.00036-5'
apa: Bowman, D. M., & Bugnet, L. A. (2026). Asteroseismology. In I. Mandel (Ed.),
Encyclopedia of Astrophysics (Vol. 2, pp. 133–153). Elsevier. https://doi.org/10.1016/b978-0-443-21439-4.00036-5
chicago: Bowman, Dominic M., and Lisa Annabelle Bugnet. “Asteroseismology.” In Encyclopedia
of Astrophysics, edited by Ilya Mandel, 2:133–53. Elsevier, 2026. https://doi.org/10.1016/b978-0-443-21439-4.00036-5.
ieee: D. M. Bowman and L. A. Bugnet, “Asteroseismology,” in Encyclopedia of Astrophysics,
vol. 2, I. Mandel, Ed. Elsevier, 2026, pp. 133–153.
ista: 'Bowman DM, Bugnet LA. 2026.Asteroseismology. In: Encyclopedia of Astrophysics.
vol. 2, 133–153.'
mla: Bowman, Dominic M., and Lisa Annabelle Bugnet. “Asteroseismology.” Encyclopedia
of Astrophysics, edited by Ilya Mandel, vol. 2, Elsevier, 2026, pp. 133–53,
doi:10.1016/b978-0-443-21439-4.00036-5.
short: D.M. Bowman, L.A. Bugnet, in:, I. Mandel (Ed.), Encyclopedia of Astrophysics,
Elsevier, 2026, pp. 133–153.
date_created: 2026-02-16T10:43:01Z
date_published: 2026-01-01T00:00:00Z
date_updated: 2026-02-17T11:05:20Z
day: '01'
department:
- _id: LiBu
doi: 10.1016/b978-0-443-21439-4.00036-5
editor:
- first_name: Ilya
full_name: Mandel, Ilya
last_name: Mandel
external_id:
arxiv:
- '2410.01715'
intvolume: ' 2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2410.01715
month: '01'
oa: 1
oa_version: Preprint
page: 133-153
publication: Encyclopedia of Astrophysics
publication_identifier:
isbn:
- '9780443214400'
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Asteroseismology
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21231'
abstract:
- lang: eng
text: To assess cell migration in complex spatial environments, microfabricated
chips, such as mazes and pillar forests, are routinely used to impose spatial
and mechanical constraints, and cell trajectories are followed within these structures
by advanced imaging techniques. In systems mechanobiology, computational models
serve as essential tools to uncover how physical geometry influences intracellular
dynamics; however, decoding such complex behaviors requires advanced inference
techniques. Here, we integrated experimental observations of dendritic cell migration
in a geometrically constrained microenvironment into a Cellular Potts model. We
demonstrated that these spatial constraints modulate the motility dynamics, including
speed and directional changes. We show that classical summary statistics, such
as mean squared displacement and turning angle distributions, can resolve key
mechanistic features but fail to extract richer spatiotemporal patterns, limiting
accurate parameter inference. To solve this, we applied neural posterior estimation
with in-the-loop learning of summary features. This learned summary representation
of the data enables robust and flexible parameter inference, providing a data-driven
framework for model calibration and advancing quantitative analysis of cell migration
in structured microenvironments.
acknowledgement: 'This work was supported by the German Federal Ministry of Education
and Research (BMBF) (EMUNE/031L0293C), the European Union via the ERC grant INTEGRATE,
grant agreement number 101126146, and under Germany’s Excellence Strategy by the
Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) (EXC 2047—390685813,
EXC 2151—390873048, FOR5775 — 533863915, and 524747443), the University of Bonn
via the Schlegel Professorship of J.H., and the returning experts fellowship of
the Ministry of Innovation, Science, and Research of North-Rhine-Westphalia (AZ:
421-8.03.03.02-137069). J.M. is a member of the Nanofabrication Facility and is
supported by the Institute of Science and Technology Austria. E.K. acknowledges
the TRA Life and Health (University of Bonn) as part of the Excellence Strategy
of the federal and state governments. The authors thank Laeschkir Würthner for his
insightful comments on the implementation of the authors’ model. The views and opinions
expressed are those of the authors only and do not necessarily reflect those of
the funding agencies. Parts of Fig. 1 were created using BioRender. Open Access
funding enabled and organized by Projekt DEAL.'
article_number: '20'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Jonas
full_name: Arruda, Jonas
last_name: Arruda
- first_name: Emad
full_name: Alamoudi, Emad
last_name: Alamoudi
- first_name: Robert
full_name: Mueller, Robert
last_name: Mueller
- first_name: Marc
full_name: Vaisband, Marc
last_name: Vaisband
- first_name: Ronja
full_name: Molkenbur, Ronja
last_name: Molkenbur
- first_name: Jack
full_name: Merrin, Jack
id: 4515C308-F248-11E8-B48F-1D18A9856A87
last_name: Merrin
orcid: 0000-0001-5145-4609
- first_name: Eva
full_name: Kiermaier, Eva
last_name: Kiermaier
- first_name: Jan
full_name: Hasenauer, Jan
last_name: Hasenauer
citation:
ama: Arruda J, Alamoudi E, Mueller R, et al. Simulation-based inference of cell
migration dynamics in complex spatial environments. npj Systems Biology and
Applications. 2026;12. doi:10.1038/s41540-026-00648-9
apa: Arruda, J., Alamoudi, E., Mueller, R., Vaisband, M., Molkenbur, R., Merrin,
J., … Hasenauer, J. (2026). Simulation-based inference of cell migration dynamics
in complex spatial environments. Npj Systems Biology and Applications.
Springer Nature. https://doi.org/10.1038/s41540-026-00648-9
chicago: Arruda, Jonas, Emad Alamoudi, Robert Mueller, Marc Vaisband, Ronja Molkenbur,
Jack Merrin, Eva Kiermaier, and Jan Hasenauer. “Simulation-Based Inference of
Cell Migration Dynamics in Complex Spatial Environments.” Npj Systems Biology
and Applications. Springer Nature, 2026. https://doi.org/10.1038/s41540-026-00648-9.
ieee: J. Arruda et al., “Simulation-based inference of cell migration dynamics
in complex spatial environments,” npj Systems Biology and Applications,
vol. 12. Springer Nature, 2026.
ista: Arruda J, Alamoudi E, Mueller R, Vaisband M, Molkenbur R, Merrin J, Kiermaier
E, Hasenauer J. 2026. Simulation-based inference of cell migration dynamics in
complex spatial environments. npj Systems Biology and Applications. 12, 20.
mla: Arruda, Jonas, et al. “Simulation-Based Inference of Cell Migration Dynamics
in Complex Spatial Environments.” Npj Systems Biology and Applications,
vol. 12, 20, Springer Nature, 2026, doi:10.1038/s41540-026-00648-9.
short: J. Arruda, E. Alamoudi, R. Mueller, M. Vaisband, R. Molkenbur, J. Merrin,
E. Kiermaier, J. Hasenauer, Npj Systems Biology and Applications 12 (2026).
date_created: 2026-02-16T10:44:31Z
date_published: 2026-02-05T00:00:00Z
date_updated: 2026-02-23T10:10:10Z
day: '05'
ddc:
- '570'
department:
- _id: NanoFab
doi: 10.1038/s41540-026-00648-9
external_id:
pmid:
- '41611727'
file:
- access_level: open_access
checksum: 99b2e6bbaaedf45f22e07751948669f5
content_type: application/pdf
creator: dernst
date_created: 2026-02-23T10:09:03Z
date_updated: 2026-02-23T10:09:03Z
file_id: '21346'
file_name: 2026_npjSysBioApp_Arruda.pdf
file_size: 10217687
relation: main_file
success: 1
file_date_updated: 2026-02-23T10:09:03Z
has_accepted_license: '1'
intvolume: ' 12'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
pmid: 1
publication: npj Systems Biology and Applications
publication_identifier:
eissn:
- 2056-7189
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Simulation-based inference of cell migration dynamics in complex spatial environments
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21232'
abstract:
- lang: eng
text: "Abstract\r\n In this paper,
we consider a simple class of stratified spaces – 2-complexes. We present an algorithm
that learns the abstract structure of an embedded 2-complex from a point cloud
sampled from it. We use tools and inspiration from computational geometry, algebraic
topology, and topological data analysis and prove the correctness of the identified
abstract structure under assumptions on the embedding."
acknowledgement: The author would like to thank Kate Turner, Chris Williams, Jonathan
Spreer, Stephan Tillmann, Vanessa Robins, Vigleik Angeltveit, Martin Helmer, and
James Morgan for very helpful discussions; and thanks Sara Kališnik Hintz and Paul
Bendich for comments on an earlier version. Additonally, the author would like to
thank both reviewers for their very insightful and helpful comments, without which
the paper would be infinitely less coherent than it currently is. Open access funding
provided by Institute of Science and Technology (IST Austria). The work in this
paper was supported by an Australian Federal Government Grant, 2019-2022, Stratified
Space Learning.
article_number: '17'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Yossi
full_name: Bleile, Yossi
id: 920a7385-7995-11ef-9bfd-8c434cd8f3c2
last_name: Bleile
orcid: 0000-0002-4861-9174
citation:
ama: 'Bleile Y. Towards stratified space learning: 2-complexes. La Matematica.
2026;5. doi:10.1007/s44007-025-00183-9'
apa: 'Bleile, Y. (2026). Towards stratified space learning: 2-complexes. La Matematica.
Springer Nature. https://doi.org/10.1007/s44007-025-00183-9'
chicago: 'Bleile, Yossi. “Towards Stratified Space Learning: 2-Complexes.” La
Matematica. Springer Nature, 2026. https://doi.org/10.1007/s44007-025-00183-9.'
ieee: 'Y. Bleile, “Towards stratified space learning: 2-complexes,” La Matematica,
vol. 5. Springer Nature, 2026.'
ista: 'Bleile Y. 2026. Towards stratified space learning: 2-complexes. La Matematica.
5, 17.'
mla: 'Bleile, Yossi. “Towards Stratified Space Learning: 2-Complexes.” La Matematica,
vol. 5, 17, Springer Nature, 2026, doi:10.1007/s44007-025-00183-9.'
short: Y. Bleile, La Matematica 5 (2026).
corr_author: '1'
date_created: 2026-02-16T10:44:44Z
date_published: 2026-02-08T00:00:00Z
date_updated: 2026-02-23T10:20:10Z
day: '08'
ddc:
- '510'
department:
- _id: HeEd
doi: 10.1007/s44007-025-00183-9
external_id:
arxiv:
- '2305.02724'
file:
- access_level: open_access
checksum: 6cae2efb47b025af22a8539c606a4e09
content_type: application/pdf
creator: dernst
date_created: 2026-02-23T10:18:52Z
date_updated: 2026-02-23T10:18:52Z
file_id: '21347'
file_name: 2026_LaMatematica_Bleile.pdf
file_size: 15051582
relation: main_file
success: 1
file_date_updated: 2026-02-23T10:18:52Z
has_accepted_license: '1'
intvolume: ' 5'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
publication: La Matematica
publication_identifier:
issn:
- 2730-9657
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Towards stratified space learning: 2-complexes'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21233'
abstract:
- lang: eng
text: Potential self-perpetuating dieback of the Amazon rain forest has been a topic
of concern. The concern is that initial deforestation could critically impair
the forest’s water recycling capacities, further harming the remaining forest
through reduced annual precipitation. Many studies have focused on annual mean
precipitation changes, due to its widespread perception as a central control on
the Amazon rain forest’s stability. However, the impact of deforestation goes
beyond changes in the annual mean precipitation. Yet, global coarse-resolution
climate models are not well suited to investigate changes in short-duration and
localized events due to their coarse resolution. Here, we circumvent these issues
by analyzing a full-deforestation scenario simulated by a global storm-resolving
model. We focus on changes in the tail of the hourly distribution of precipitation,
temperature, and wind. Hourly precipitation becomes more extreme in the absence
of the forest than in an intact forest, with an increased occurrence of both no
rain and intense rainfall. These changes are driven by enhanced moisture convergence
that strengthens vertical velocity. On average, the near-surface temperature rises
significantly by about 3.84 °C, and the daily minimum temperature after deforestation
becomes similar to the daily maximum temperature before deforestation. Except
for wet-bulb temperature, human heat stress indicators shift to more severe levels,
with implications for health and a significant reduction in work productivity.
Finally, the mean 10 m wind speed intensifies by a factor of four, with the 99th
percentile wind speed doubling. To summarize, our findings, while based on an
idealized case, provide a stark warning of the effects of continuing deforestation
of the Amazon.
acknowledgement: AY acknowledges funding by the CLICCS centre of excellence subproject
A3 funded by DFG. We thank the German Climate Computing Center DKRZ for providing
computing resources and the Integrated Climate Data Center (ICDC), the Center for
Earth System Research and Sustainability (CEN), University of Hamburg, for supporting
the IMERG data. In addition, we would like to thank Jana Sillmann for suggesting
the analysis of heat stress indices and Keno Riechers for providing a thorough internal
review of the initial manuscript at the Max Planck Institute for Meteorology. Open
Access funding is enabled and organized by Projekt DEAL. This research has been
supported by the Deutsche Forschungsgemeinschaft (grant no. CLICCS 390683824 (A3)).
The article processing charges for this open-access publication were covered by
the Max Planck Society.
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Arim
full_name: Yoon, Arim
last_name: Yoon
- first_name: Cathy
full_name: Hohenegger, Cathy
last_name: Hohenegger
- first_name: Jiawei
full_name: Bao, Jiawei
id: bb9a7399-fefd-11ed-be3c-ae648fd1d160
last_name: Bao
- first_name: Lukas
full_name: Brunner, Lukas
last_name: Brunner
citation:
ama: Yoon A, Hohenegger C, Bao J, Brunner L. Extreme events in the Amazon after
deforestation. Earth System Dynamics. 2026;17(1):167-179. doi:10.5194/esd-17-167-2026
apa: Yoon, A., Hohenegger, C., Bao, J., & Brunner, L. (2026). Extreme events
in the Amazon after deforestation. Earth System Dynamics. Copernicus GmbH.
https://doi.org/10.5194/esd-17-167-2026
chicago: Yoon, Arim, Cathy Hohenegger, Jiawei Bao, and Lukas Brunner. “Extreme Events
in the Amazon after Deforestation.” Earth System Dynamics. Copernicus GmbH,
2026. https://doi.org/10.5194/esd-17-167-2026.
ieee: A. Yoon, C. Hohenegger, J. Bao, and L. Brunner, “Extreme events in the Amazon
after deforestation,” Earth System Dynamics, vol. 17, no. 1. Copernicus
GmbH, pp. 167–179, 2026.
ista: Yoon A, Hohenegger C, Bao J, Brunner L. 2026. Extreme events in the Amazon
after deforestation. Earth System Dynamics. 17(1), 167–179.
mla: Yoon, Arim, et al. “Extreme Events in the Amazon after Deforestation.” Earth
System Dynamics, vol. 17, no. 1, Copernicus GmbH, 2026, pp. 167–79, doi:10.5194/esd-17-167-2026.
short: A. Yoon, C. Hohenegger, J. Bao, L. Brunner, Earth System Dynamics 17 (2026)
167–179.
date_created: 2026-02-16T10:44:58Z
date_published: 2026-02-04T00:00:00Z
date_updated: 2026-02-23T10:28:48Z
day: '04'
ddc:
- '550'
department:
- _id: CaMu
doi: 10.5194/esd-17-167-2026
file:
- access_level: open_access
checksum: 6c3669c463731ad7c484b2990eb8ee0d
content_type: application/pdf
creator: dernst
date_created: 2026-02-23T10:26:29Z
date_updated: 2026-02-23T10:26:29Z
file_id: '21348'
file_name: 2026_EarthSystDynam_Yoon.pdf
file_size: 2068229
relation: main_file
success: 1
file_date_updated: 2026-02-23T10:26:29Z
has_accepted_license: '1'
intvolume: ' 17'
issue: '1'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: 167-179
publication: Earth System Dynamics
publication_identifier:
eissn:
- 2190-4987
publication_status: published
publisher: Copernicus GmbH
quality_controlled: '1'
scopus_import: '1'
status: public
title: Extreme events in the Amazon after deforestation
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21234'
abstract:
- lang: eng
text: In aged humans and mice, hypobranched glycogen aggregates, known as polyglucosan
bodies (PGBs), accumulate in hippocampal astrocytes. While PGBs are linked to
cognitive decline in neurological diseases, they remain largely unstudied in the
context of typical aging. We show that PGBs arise in autophagy-dysregulated astrocytes
in the aged hippocampus, with substantial variation among 32 inbred BXD mouse
strains. Genetic mapping through quantitative trait locus analysis identified
a major locus (Pgb1) that modulates hippocampal PGB burden. Extensive transcriptomic
and proteomic datasets were produced for the aged hippocampus of the BXD family
to investigate the mechanism by which the Pgb1 locus modulates PGB burden. We
identified that Pgb1 contains allelic Smarcal1 and Usp37 variants and influences
PGB burden through trans-regulation of mRNA and protein expression levels, including
abundance of glycogen-mobilizing factor PYGB. Furthermore, comprehensive phenome-wide
association scans, transcriptomic analyses, and direct behavioral testing demonstrated
that cognition remains intact despite age-related PGB burden. A record of this
paper’s transparent peer review process is included in the supplemental information.
acknowledgement: We would like to thank the Summer School Systems Genetics of Neural
Ageing for bringing us together and spurring our international collaboration. We
would also like to acknowledge the funding for the Summer School 2022 from the e:Med
Systems Medicine Program of the BMBF (Bundesministerium für Bildung und Forschung;
German Ministry of Education and Research) to R.W.O. In addition, we would like
to thank the FLI imaging core facility for their assistance. A.G.-P. is supported
by Fundación Séneca, Región de Murcia, Spain (21259/FPI/19). D.E.M.d.B. is financed
by a Rubicon scholarship (452021116) from the Dutch Research Council (NWO). This
work was also supported by NIH NIA R01AG070913-01 (R.W.W.), R01AG075813-01 (D.G.A.),
and R01AG075818 (C.K.). We acknowledge the help of Larry Mobraaten (Jackson Laboratory,
Bar Harbor, MN) with the BXD strains and U. Obermüller for the help with the histology.
For the purpose of open access, the authors have applied a CC BY public copyright
license to all author-accepted manuscripts arising from this submission.
article_number: '101488'
article_processing_charge: No
article_type: original
author:
- first_name: Alicia
full_name: Gómez-Pascual, Alicia
last_name: Gómez-Pascual
- first_name: Dow M
full_name: Glikman, Dow M
id: ab8acda1-91c1-11f0-aad8-f75d3d6424d8
last_name: Glikman
- first_name: Hui Xin
full_name: Ng, Hui Xin
last_name: Ng
- first_name: James E.
full_name: Tomkins, James E.
last_name: Tomkins
- first_name: Lu
full_name: Lu, Lu
last_name: Lu
- first_name: Ying
full_name: Xu, Ying
last_name: Xu
- first_name: David G.
full_name: Ashbrook, David G.
last_name: Ashbrook
- first_name: Catherine
full_name: Kaczorowski, Catherine
last_name: Kaczorowski
- first_name: Gerd
full_name: Kempermann, Gerd
last_name: Kempermann
- first_name: John
full_name: Killmar, John
last_name: Killmar
- first_name: Khyobeni
full_name: Mozhui, Khyobeni
last_name: Mozhui
- first_name: Oliver
full_name: Ohlenschläger, Oliver
last_name: Ohlenschläger
- first_name: Rudolf
full_name: Aebersold, Rudolf
last_name: Aebersold
- first_name: Donald K.
full_name: Ingram, Donald K.
last_name: Ingram
- first_name: Evan G.
full_name: Williams, Evan G.
last_name: Williams
- first_name: Mathias
full_name: Jucker, Mathias
last_name: Jucker
- first_name: Rupert W.
full_name: Overall, Rupert W.
last_name: Overall
- first_name: Robert W.
full_name: Williams, Robert W.
last_name: Williams
- first_name: Dennis E.M.
full_name: de Bakker, Dennis E.M.
last_name: de Bakker
citation:
ama: Gómez-Pascual A, Glikman DM, Ng HX, et al. The Smarcal1-Usp37 locus modulates
glycogen aggregation in astrocytes of the aged hippocampus. Cell Systems.
2026;17(2). doi:10.1016/j.cels.2025.101488
apa: Gómez-Pascual, A., Glikman, D. M., Ng, H. X., Tomkins, J. E., Lu, L., Xu, Y.,
… de Bakker, D. E. M. (2026). The Smarcal1-Usp37 locus modulates glycogen aggregation
in astrocytes of the aged hippocampus. Cell Systems. Elsevier. https://doi.org/10.1016/j.cels.2025.101488
chicago: Gómez-Pascual, Alicia, Dow M Glikman, Hui Xin Ng, James E. Tomkins, Lu
Lu, Ying Xu, David G. Ashbrook, et al. “The Smarcal1-Usp37 Locus Modulates Glycogen
Aggregation in Astrocytes of the Aged Hippocampus.” Cell Systems. Elsevier,
2026. https://doi.org/10.1016/j.cels.2025.101488.
ieee: A. Gómez-Pascual et al., “The Smarcal1-Usp37 locus modulates glycogen
aggregation in astrocytes of the aged hippocampus,” Cell Systems, vol.
17, no. 2. Elsevier, 2026.
ista: Gómez-Pascual A, Glikman DM, Ng HX, Tomkins JE, Lu L, Xu Y, Ashbrook DG, Kaczorowski
C, Kempermann G, Killmar J, Mozhui K, Ohlenschläger O, Aebersold R, Ingram DK,
Williams EG, Jucker M, Overall RW, Williams RW, de Bakker DEM. 2026. The Smarcal1-Usp37
locus modulates glycogen aggregation in astrocytes of the aged hippocampus. Cell
Systems. 17(2), 101488.
mla: Gómez-Pascual, Alicia, et al. “The Smarcal1-Usp37 Locus Modulates Glycogen
Aggregation in Astrocytes of the Aged Hippocampus.” Cell Systems, vol.
17, no. 2, 101488, Elsevier, 2026, doi:10.1016/j.cels.2025.101488.
short: A. Gómez-Pascual, D.M. Glikman, H.X. Ng, J.E. Tomkins, L. Lu, Y. Xu, D.G.
Ashbrook, C. Kaczorowski, G. Kempermann, J. Killmar, K. Mozhui, O. Ohlenschläger,
R. Aebersold, D.K. Ingram, E.G. Williams, M. Jucker, R.W. Overall, R.W. Williams,
D.E.M. de Bakker, Cell Systems 17 (2026).
date_created: 2026-02-16T10:45:10Z
date_published: 2026-02-18T00:00:00Z
date_updated: 2026-02-23T10:35:01Z
day: '18'
ddc:
- '570'
department:
- _id: GradSch
doi: 10.1016/j.cels.2025.101488
external_id:
pmid:
- '41633365'
file:
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checksum: 920e8edfd3b8b42f5bb6f86d4c66c54d
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date_created: 2026-02-23T10:32:12Z
date_updated: 2026-02-23T10:32:12Z
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file_size: 10606778
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oa_version: Published Version
pmid: 1
publication: Cell Systems
publication_identifier:
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publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: The Smarcal1-Usp37 locus modulates glycogen aggregation in astrocytes of the
aged hippocampus
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '21242'
abstract:
- lang: eng
text: We obtain an asymptotic formula for the number of integral solutions to a
system of diagonal equations. We obtain an asymptotic formula for the number of
solutions with variables restricted to smooth numbers as well. We improve the
required number of variables compared to previous results by incorporating recent
progress on Waring’s problem and the resolution of the main conjecture in Vinogradov’s
mean value theorem.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Nick
full_name: Rome, Nick
last_name: Rome
- first_name: Shuntaro
full_name: Yamagishi, Shuntaro
id: 0c3fbc5c-f7a6-11ec-8d70-9485e75b416b
last_name: Yamagishi
citation:
ama: Rome N, Yamagishi S. Integral solutions to systems of diagonal equations. Pacific
Journal of Mathematics. 2026;340(1):179-198. doi:10.2140/pjm.2026.340.179
apa: Rome, N., & Yamagishi, S. (2026). Integral solutions to systems of diagonal
equations. Pacific Journal of Mathematics. Mathematical Sciences Publishers.
https://doi.org/10.2140/pjm.2026.340.179
chicago: Rome, Nick, and Shuntaro Yamagishi. “Integral Solutions to Systems of Diagonal
Equations.” Pacific Journal of Mathematics. Mathematical Sciences Publishers,
2026. https://doi.org/10.2140/pjm.2026.340.179.
ieee: N. Rome and S. Yamagishi, “Integral solutions to systems of diagonal equations,”
Pacific Journal of Mathematics, vol. 340, no. 1. Mathematical Sciences
Publishers, pp. 179–198, 2026.
ista: Rome N, Yamagishi S. 2026. Integral solutions to systems of diagonal equations.
Pacific Journal of Mathematics. 340(1), 179–198.
mla: Rome, Nick, and Shuntaro Yamagishi. “Integral Solutions to Systems of Diagonal
Equations.” Pacific Journal of Mathematics, vol. 340, no. 1, Mathematical
Sciences Publishers, 2026, pp. 179–98, doi:10.2140/pjm.2026.340.179.
short: N. Rome, S. Yamagishi, Pacific Journal of Mathematics 340 (2026) 179–198.
date_created: 2026-02-16T15:17:27Z
date_published: 2026-01-01T00:00:00Z
date_updated: 2026-02-17T11:43:14Z
day: '01'
department:
- _id: TiBr
doi: 10.2140/pjm.2026.340.179
external_id:
arxiv:
- '2406.09256'
intvolume: ' 340'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2406.09256
month: '01'
oa: 1
oa_version: Preprint
page: 179-198
publication: Pacific Journal of Mathematics
publication_identifier:
eissn:
- 1945-5844
issn:
- 0030-8730
publication_status: published
publisher: Mathematical Sciences Publishers
quality_controlled: '1'
status: public
title: Integral solutions to systems of diagonal equations
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 340
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '21273'
abstract:
- lang: eng
text: In this paper we examine how porosity fluctuations affect the hydrodynamic
permeability of a porous matrix or membrane. We introduce a fluctuating Darcy
model, which couples the Navier-Stokes equation to the space- and time-dependent
porosity fluctuations via a Darcy friction term. Using a perturbative approach,
a Dyson equation for hydrodynamic fluctuations is derived and solved to express
the permeability in terms of the matrix fluctuation spectrum. Surprisingly, the
model reveals strong modifications of the fluid permeability in fluctuating matrices
compared to static ones. Applications to various matrix excitation models, the
breathing matrix, phonons, and active forcing, highlight the significant influence
of matrix fluctuations on fluid transport, offering insights for optimizing membrane
design for separation applications.
acknowledgement: "The authors acknowledge support from ERC project n-AQUA, Grant Agreement
No. 101071937.\r\nB.C. and A.S. acknowledge support from the CFM Foundation. B.C.
acknowledges support from\r\nthe NOMIS Foundation."
article_number: '014201'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Albert
full_name: Dombret, Albert
last_name: Dombret
- first_name: Adrien
full_name: Sutter, Adrien
last_name: Sutter
- first_name: Baptiste
full_name: Coquinot, Baptiste
id: f8417bd4-f599-11ee-a482-b927e3ed1e8e
last_name: Coquinot
orcid: 0000-0001-5524-596X
- first_name: Nikita
full_name: Kavokine, Nikita
last_name: Kavokine
- first_name: Benoit
full_name: Coasne, Benoit
last_name: Coasne
- first_name: Lydéric
full_name: Bocquet, Lydéric
last_name: Bocquet
citation:
ama: Dombret A, Sutter A, Coquinot B, Kavokine N, Coasne B, Bocquet L. Hydrodynamic
permeability of fluctuating porous membranes. Physical Review Fluids. 2026;11(1).
doi:10.1103/m8h6-1wfk
apa: Dombret, A., Sutter, A., Coquinot, B., Kavokine, N., Coasne, B., & Bocquet,
L. (2026). Hydrodynamic permeability of fluctuating porous membranes. Physical
Review Fluids. American Physical Society. https://doi.org/10.1103/m8h6-1wfk
chicago: Dombret, Albert, Adrien Sutter, Baptiste Coquinot, Nikita Kavokine, Benoit
Coasne, and Lydéric Bocquet. “Hydrodynamic Permeability of Fluctuating Porous
Membranes.” Physical Review Fluids. American Physical Society, 2026. https://doi.org/10.1103/m8h6-1wfk.
ieee: A. Dombret, A. Sutter, B. Coquinot, N. Kavokine, B. Coasne, and L. Bocquet,
“Hydrodynamic permeability of fluctuating porous membranes,” Physical Review
Fluids, vol. 11, no. 1. American Physical Society, 2026.
ista: Dombret A, Sutter A, Coquinot B, Kavokine N, Coasne B, Bocquet L. 2026. Hydrodynamic
permeability of fluctuating porous membranes. Physical Review Fluids. 11(1), 014201.
mla: Dombret, Albert, et al. “Hydrodynamic Permeability of Fluctuating Porous Membranes.”
Physical Review Fluids, vol. 11, no. 1, 014201, American Physical Society,
2026, doi:10.1103/m8h6-1wfk.
short: A. Dombret, A. Sutter, B. Coquinot, N. Kavokine, B. Coasne, L. Bocquet, Physical
Review Fluids 11 (2026).
corr_author: '1'
date_created: 2026-02-17T08:10:09Z
date_published: 2026-01-21T00:00:00Z
date_updated: 2026-02-23T12:01:57Z
day: '21'
department:
- _id: MiLe
doi: 10.1103/m8h6-1wfk
external_id:
arxiv:
- '2512.11368'
intvolume: ' 11'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2512.11368
month: '01'
oa: 1
oa_version: Preprint
publication: Physical Review Fluids
publication_identifier:
eissn:
- 2469-990X
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
status: public
title: Hydrodynamic permeability of fluctuating porous membranes
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21274'
abstract:
- lang: eng
text: "Many white dwarfs are observed in compact double white dwarf binaries, and
through the emission of gravitational waves, a large fraction are destined to
merge. The merger remnants that do not explode in a Type Ia supernova are expected
to initially be rapidly rotating and highly magnetized. In this work, we present
our discovery of the variable white dwarf ZTF J200832.79+444939.67, hereafter
ZTF J2008+4449, as a likely merger remnant showing signs of circumstellar material
without a stellar or substellar companion. The nature of ZTF J2008+4449 as a merger
remnant is supported by its physical properties: it is hot (35 500 ± 300 K) and
massive (1.12 ± 0.03 M\r\n ⊙\r\n ),
rapidly rotating with a period of ≈6.6 minutes, and likely possesses exceptionally
strong magnetic fields (∼400−600 MG) at its surface. Remarkably, we detect a significant
period derivative of (1.80 ± 0.09)×10\r\n −12\r\n
\ s/s, indicating that the white dwarf is spinning down, and
a soft X-ray emission that is inconsistent with photospheric emission. As the
presence of a mass-transferring stellar or brown dwarf companion is excluded by
infrared photometry, the detected spin-down and X-ray emission could be tell-tale
signs of a magnetically driven wind or of interaction with circumstellar material,
possibly originating from the fallback of gravitationally bound merger ejecta
or from the tidal disruption of a planetary object. We also detect Balmer emission,
which requires the presence of ionized hydrogen in the vicinity of the white dwarf,
showing Doppler shifts as high as ≈2000 km s\r\n −1\r\n
\ . The unusual variability of the Balmer emission on the spin
period of the white dwarf is consistent with the trapping of a half ring of ionized
gas in the magnetosphere of the white dwarf.\r\n "
acknowledgement: "We thank Lynne Hillenbrand and Soumyadeep Bhattacharjee for helpful
discussions, and Kishalay De for his help with the WIRC\r\nreduction pipeline. IC
was supported by NASA through grants from the Space\r\nTelescope Science Institute,
under NASA contracts NASA.22K1813, NAS5-\r\n26555 and NAS5-03127. TC was supported
by NASA through the NASA Hubble\r\nFellowship grant HST-HF2-51527.001-A awarded
by the Space Telescope Science Institute, which is operated by the Association of
Universities for Research\r\nin Astronomy, Inc., for NASA, under contract NAS5-26555.
This project has\r\nreceived funding from the European Research Council (ERC) under
the European Union’s Horizon 2020 research and innovation programme (Grant agreement
No. 101020057). This work was based on observations obtained with the\r\nSamuel
Oschin Telescope 48-inch and the 60-inch Telescope at the Palomar\r\nObservatory
as part of the Zwicky Transient Facility project. ZTF is supported\r\nby the National
Science Foundation under Grants No. AST-1440341, AST2034437, and currently Award
#2407588. ZTF receives additional funding from\r\nthe ZTF partnership. Current members
include Caltech, USA; Caltech/IPAC,\r\nUSA; University of Maryland, USA; University
of California, Berkeley, USA;\r\nUniversity of Wisconsin at Milwaukee, USA; Cornell
University, USA; Drexel\r\nUniversity, USA; University of North Carolina at Chapel
Hill, USA; Institute\r\nof Science and Technology, Austria; National Central University,
Taiwan, and\r\nOKC, University of Stockholm, Sweden. Operations are conducted by
Caltech’s\r\nOptical Observatory (COO), Caltech/IPAC, and the University of Washington
at\r\nSeattle, USA. This work has made use of data from the European Space Agency\r\n(ESA)
mission Gaia (https://www.cosmos.esa.int/gaia), processed by\r\nthe Gaia Data Processing
and Analysis Consortium (DPAC, https://www.\r\ncosmos.esa.int/web/gaia/dpac/consortium).
Funding for the DPAC has been provided by national institutions, in particular the
institutions participating in the Gaia Multilateral Agreement. The Pan-STARRS1 Surveys
(PS1)\r\nand the PS1 public science archive have been made possible through contributions
by the Institute for Astronomy, the University of Hawaii, the PanSTARRS Project
Office, the Max-Planck Society and its participating institutes, the Max Planck
Institute for Astronomy, Heidelberg and the Max Planck\r\nInstitute for Extraterrestrial
Physics, Garching, The Johns Hopkins University,\r\nDurham University, the University
of Edinburgh, the Queen’s University Belfast,\r\nthe Harvard-Smithsonian Center
for Astrophysics, the Las Cumbres Observatory Global Telescope Network Incorporated,
the National Central University of Taiwan, the Space Telescope Science Institute,
the National Aeronautics and Space Administration under Grant No. NNX08AR22G issued
through\r\nthe Planetary Science Division of the NASA Science Mission Directorate,
the\r\nNational Science Foundation Grant No. AST–1238877, the University of Maryland,
Eotvos Lorand University (ELTE), the Los Alamos National Laboratory,\r\nand the
Gordon and Betty Moore Foundation. This work made use of Astropy\r\n(http://www.astropy.org):
a community-developed core Python package\r\nand an ecosystem of tools and resources
for astronomy (Astropy Collaboration\r\n2013, 2018, 2022)."
article_number: A188
article_processing_charge: Yes
article_type: original
author:
- first_name: Andrei-Alexandru
full_name: Cristea, Andrei-Alexandru
id: 4d500bea-31f8-11ee-a48d-d4904fb363c7
last_name: Cristea
- first_name: Ilaria
full_name: Caiazzo, Ilaria
id: 8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d
last_name: Caiazzo
orcid: 0000-0002-4770-5388
- first_name: Tim
full_name: Cunningham, Tim
last_name: Cunningham
- first_name: John C.
full_name: Raymond, John C.
last_name: Raymond
- first_name: Stephane
full_name: Vennes, Stephane
last_name: Vennes
- first_name: Adela
full_name: Kawka, Adela
last_name: Kawka
- first_name: Aayush A
full_name: Desai, Aayush A
id: 502cfd30-32c1-11ee-a9a4-d8dad5c6739e
last_name: Desai
- first_name: David R.
full_name: Miller, David R.
last_name: Miller
- first_name: J. J.
full_name: Hermes, J. J.
last_name: Hermes
- first_name: Jim
full_name: Fuller, Jim
last_name: Fuller
- first_name: Jeremy
full_name: Heyl, Jeremy
last_name: Heyl
- first_name: Jan
full_name: van Roestel, Jan
last_name: van Roestel
- first_name: Kevin B.
full_name: Burdge, Kevin B.
last_name: Burdge
- first_name: Antonio C.
full_name: Rodriguez, Antonio C.
last_name: Rodriguez
- first_name: Ingrid
full_name: Pelisoli, Ingrid
last_name: Pelisoli
- first_name: Boris T.
full_name: Gänsicke, Boris T.
last_name: Gänsicke
- first_name: Paula
full_name: Szkody, Paula
last_name: Szkody
- first_name: Scott J.
full_name: Kenyon, Scott J.
last_name: Kenyon
- first_name: Zach
full_name: Vanderbosch, Zach
last_name: Vanderbosch
- first_name: Andrew
full_name: Drake, Andrew
last_name: Drake
- first_name: Lilia
full_name: Ferrario, Lilia
last_name: Ferrario
- first_name: Dayal
full_name: Wickramasinghe, Dayal
last_name: Wickramasinghe
- first_name: Viraj R.
full_name: Karambelkar, Viraj R.
last_name: Karambelkar
- first_name: Stephen
full_name: Justham, Stephen
last_name: Justham
- first_name: Ruediger
full_name: Pakmor, Ruediger
last_name: Pakmor
- first_name: Kareem
full_name: El-Badry, Kareem
last_name: El-Badry
- first_name: Thomas
full_name: Prince, Thomas
last_name: Prince
- first_name: S. R.
full_name: Kulkarni, S. R.
last_name: Kulkarni
- first_name: Matthew J.
full_name: Graham, Matthew J.
last_name: Graham
- first_name: Frank J.
full_name: Masci, Frank J.
last_name: Masci
- first_name: Steven L.
full_name: Groom, Steven L.
last_name: Groom
- first_name: Josiah
full_name: Purdum, Josiah
last_name: Purdum
- first_name: Richard
full_name: Dekany, Richard
last_name: Dekany
- first_name: Eric C.
full_name: Bellm, Eric C.
last_name: Bellm
citation:
ama: Cristea A-A, Caiazzo I, Cunningham T, et al. A half ring of ionized circumstellar
material trapped in the magnetosphere of a white dwarf merger remnant. Astronomy
& Astrophysics. 2026;706. doi:10.1051/0004-6361/202556432
apa: Cristea, A.-A., Caiazzo, I., Cunningham, T., Raymond, J. C., Vennes, S., Kawka,
A., … Bellm, E. C. (2026). A half ring of ionized circumstellar material trapped
in the magnetosphere of a white dwarf merger remnant. Astronomy & Astrophysics.
EDP Sciences. https://doi.org/10.1051/0004-6361/202556432
chicago: Cristea, Andrei-Alexandru, Ilaria Caiazzo, Tim Cunningham, John C. Raymond,
Stephane Vennes, Adela Kawka, Aayush A Desai, et al. “A Half Ring of Ionized Circumstellar
Material Trapped in the Magnetosphere of a White Dwarf Merger Remnant.” Astronomy
& Astrophysics. EDP Sciences, 2026. https://doi.org/10.1051/0004-6361/202556432.
ieee: A.-A. Cristea et al., “A half ring of ionized circumstellar material
trapped in the magnetosphere of a white dwarf merger remnant,” Astronomy &
Astrophysics, vol. 706. EDP Sciences, 2026.
ista: Cristea A-A, Caiazzo I, Cunningham T, Raymond JC, Vennes S, Kawka A, Desai
AA, Miller DR, Hermes JJ, Fuller J, Heyl J, van Roestel J, Burdge KB, Rodriguez
AC, Pelisoli I, Gänsicke BT, Szkody P, Kenyon SJ, Vanderbosch Z, Drake A, Ferrario
L, Wickramasinghe D, Karambelkar VR, Justham S, Pakmor R, El-Badry K, Prince T,
Kulkarni SR, Graham MJ, Masci FJ, Groom SL, Purdum J, Dekany R, Bellm EC. 2026.
A half ring of ionized circumstellar material trapped in the magnetosphere of
a white dwarf merger remnant. Astronomy & Astrophysics. 706, A188.
mla: Cristea, Andrei-Alexandru, et al. “A Half Ring of Ionized Circumstellar Material
Trapped in the Magnetosphere of a White Dwarf Merger Remnant.” Astronomy &
Astrophysics, vol. 706, A188, EDP Sciences, 2026, doi:10.1051/0004-6361/202556432.
short: A.-A. Cristea, I. Caiazzo, T. Cunningham, J.C. Raymond, S. Vennes, A. Kawka,
A.A. Desai, D.R. Miller, J.J. Hermes, J. Fuller, J. Heyl, J. van Roestel, K.B.
Burdge, A.C. Rodriguez, I. Pelisoli, B.T. Gänsicke, P. Szkody, S.J. Kenyon, Z.
Vanderbosch, A. Drake, L. Ferrario, D. Wickramasinghe, V.R. Karambelkar, S. Justham,
R. Pakmor, K. El-Badry, T. Prince, S.R. Kulkarni, M.J. Graham, F.J. Masci, S.L.
Groom, J. Purdum, R. Dekany, E.C. Bellm, Astronomy & Astrophysics 706 (2026).
corr_author: '1'
date_created: 2026-02-17T08:12:05Z
date_published: 2026-02-10T00:00:00Z
date_updated: 2026-02-23T12:10:34Z
day: '10'
ddc:
- '520'
department:
- _id: IlCa
- _id: GradSch
doi: 10.1051/0004-6361/202556432
file:
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checksum: 229b688e6e78cab5bb8e2bac366d1575
content_type: application/pdf
creator: dernst
date_created: 2026-02-23T12:04:37Z
date_updated: 2026-02-23T12:04:37Z
file_id: '21350'
file_name: 2026_AstronomyAstrophysics_Cristea.pdf
file_size: 5352853
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has_accepted_license: '1'
intvolume: ' 706'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
publication: Astronomy & Astrophysics
publication_identifier:
eissn:
- 1432-0746
issn:
- 0004-6361
publication_status: published
publisher: EDP Sciences
quality_controlled: '1'
status: public
title: A half ring of ionized circumstellar material trapped in the magnetosphere
of a white dwarf merger remnant
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 706
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21275'
abstract:
- lang: eng
text: DNA methylation is a primary layer of epigenetic modification that plays a
pivotal role in the regulation of development, aging, and cancer. The concurrent
activity of opposing enzymes that mediate DNA methylation and demethylation gives
rise to a biochemical cycle and active turnover of DNA methylation. While the
ensuing biochemical oscillations have been implicated in the regulation of cell
differentiation, their functional role and spatiotemporal dynamics are unknown.
In this work, we demonstrate that chromatin-mediated coupling between these local
biochemical cycles can lead to the emergence of phase-locked domains, regions
of locally synchronized turnover activity, whose coarsening is arrested by genomic
heterogeneity. We introduce a minimal model based on stochastic oscillators with
constrained long-range and nonreciprocal interactions, shaped by the local chromatin
organization. Through a combination of analytical theory and stochastic simulations,
we predict both the degree of synchronization and the typical size of emergent
phase-locked domains. We qualitatively test these predictions using single-cell
sequencing data. Our results show that DNA methylation turnover exhibits surprisingly
rich spatiotemporal patterns that may be used by cells to control cell differentiation.
acknowledgement: This project has received funding from the European Union's Horizon
2020 research and innovation programme under Grant Agreement No. 950349 and the
Marie Skłodowska-Curie Grant Agreement No. 101034413. The computations in this paper
were run in part on the the FASRC Cannon cluster supported by the FAS Division of
Science Research Computing Group at Harvard University and the cluster of the Max
Planck Institute for the Physics of Complex Systems.
article_number: '013018'
article_processing_charge: Yes
article_type: original
author:
- first_name: Fabrizio
full_name: Olmeda, Fabrizio
id: 69dbf5fb-8a76-11ed-866b-fb486d8b5689
last_name: Olmeda
- first_name: Misha
full_name: Gupta, Misha
last_name: Gupta
- first_name: Onurcan
full_name: Bektas, Onurcan
last_name: Bektas
- first_name: Steffen
full_name: Rulands, Steffen
last_name: Rulands
citation:
ama: Olmeda F, Gupta M, Bektas O, Rulands S. Spatiotemporal patterns of active epigenetic
turnover. PRX Life. 2026;4. doi:10.1103/89bj-79g5
apa: Olmeda, F., Gupta, M., Bektas, O., & Rulands, S. (2026). Spatiotemporal
patterns of active epigenetic turnover. PRX Life. American Physical Society.
https://doi.org/10.1103/89bj-79g5
chicago: Olmeda, Fabrizio, Misha Gupta, Onurcan Bektas, and Steffen Rulands. “Spatiotemporal
Patterns of Active Epigenetic Turnover.” PRX Life. American Physical Society,
2026. https://doi.org/10.1103/89bj-79g5.
ieee: F. Olmeda, M. Gupta, O. Bektas, and S. Rulands, “Spatiotemporal patterns of
active epigenetic turnover,” PRX Life, vol. 4. American Physical Society,
2026.
ista: Olmeda F, Gupta M, Bektas O, Rulands S. 2026. Spatiotemporal patterns of active
epigenetic turnover. PRX Life. 4, 013018.
mla: Olmeda, Fabrizio, et al. “Spatiotemporal Patterns of Active Epigenetic Turnover.”
PRX Life, vol. 4, 013018, American Physical Society, 2026, doi:10.1103/89bj-79g5.
short: F. Olmeda, M. Gupta, O. Bektas, S. Rulands, PRX Life 4 (2026).
corr_author: '1'
date_created: 2026-02-17T08:17:53Z
date_published: 2026-02-09T00:00:00Z
date_updated: 2026-02-24T06:54:32Z
day: '09'
ddc:
- '570'
department:
- _id: EdHa
doi: 10.1103/89bj-79g5
ec_funded: 1
file:
- access_level: open_access
checksum: df9776422862d1d02c66d98e2d620849
content_type: application/pdf
creator: dernst
date_created: 2026-02-24T06:53:05Z
date_updated: 2026-02-24T06:53:05Z
file_id: '21351'
file_name: 2026_PRXLife_Olmeda.pdf
file_size: 5857833
relation: main_file
success: 1
file_date_updated: 2026-02-24T06:53:05Z
has_accepted_license: '1'
intvolume: ' 4'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
call_identifier: H2020
grant_number: '101034413'
name: 'IST-BRIDGE: International postdoctoral program'
publication: PRX Life
publication_identifier:
eissn:
- 2835-8279
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
status: public
title: Spatiotemporal patterns of active epigenetic turnover
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 4
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21282'
abstract:
- lang: eng
text: 'Developmental patterning comprises processes that range from purely instructed,
where external signals specify cell fates, to fully self-organized, where spatial
patterns emerge autonomously through cellular interactions. We propose that both
extremes—as well as the continuum of intermediate cases—can be conceptualized
as information-processing systems, whose operation can be described using “Marr''s
three levels of analysis”: the computational problem being solved, the algorithms
employed, and their molecular implementation. At the first level, we argue that
normative theories, such as information-theoretic optimization principles, provide
a formalization of the computational problem. At the second level, we show how
simplified information-processing architectures provide a framework for developmental
algorithms, which are formalized mathematically using dynamical systems theory.
At the third level, the implementation of developmental algorithms is described
by mechanistic biophysical and gene regulatory network models.'
acknowledgement: We thank Edouard Hannezo, Anna Kicheva, Fridtjof Brauns, and all
members of the Brückner and Tkačik groups for feedback and inspiring discussions.
This work was supported in part by European Research Council ERC-2023-SyG “Dynatrans”
Grant No. 101118866 (G.T.). This work was conducted while visiting the Okinawa Institute
of Science and Technology (OIST) through the Theoretical Sciences Visiting Program
(TSVP); at the Kavli Institute for Theoretical Physics (KITP) Santa Barbara, supported
by NSF Grant No. PHY-1748958 and the Gordon and Betty Moore Foundation Grant No.
2919.02; and at Lucullus, Vienna.
article_number: '017001'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: David
full_name: Brückner, David
id: e1e86031-6537-11eb-953a-f7ab92be508d
last_name: Brückner
orcid: 0000-0001-7205-2975
- first_name: Gašper
full_name: Tkačik, Gašper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkačik
orcid: 0000-0002-6699-1455
citation:
ama: 'Brückner D, Tkačik G. Marr’s three levels for embryonic development: Information,
dynamical systems, gene networks. PRX Life. 2026;4. doi:10.1103/fdcf-dkws'
apa: 'Brückner, D., & Tkačik, G. (2026). Marr’s three levels for embryonic development:
Information, dynamical systems, gene networks. PRX Life. American Physical
Society. https://doi.org/10.1103/fdcf-dkws'
chicago: 'Brückner, David, and Gašper Tkačik. “Marr’s Three Levels for Embryonic
Development: Information, Dynamical Systems, Gene Networks.” PRX Life.
American Physical Society, 2026. https://doi.org/10.1103/fdcf-dkws.'
ieee: 'D. Brückner and G. Tkačik, “Marr’s three levels for embryonic development:
Information, dynamical systems, gene networks,” PRX Life, vol. 4. American
Physical Society, 2026.'
ista: 'Brückner D, Tkačik G. 2026. Marr’s three levels for embryonic development:
Information, dynamical systems, gene networks. PRX Life. 4, 017001.'
mla: 'Brückner, David, and Gašper Tkačik. “Marr’s Three Levels for Embryonic Development:
Information, Dynamical Systems, Gene Networks.” PRX Life, vol. 4, 017001,
American Physical Society, 2026, doi:10.1103/fdcf-dkws.'
short: D. Brückner, G. Tkačik, PRX Life 4 (2026).
corr_author: '1'
date_created: 2026-02-17T08:29:10Z
date_published: 2026-01-23T00:00:00Z
date_updated: 2026-02-24T07:00:16Z
day: '23'
ddc:
- '570'
department:
- _id: GaTk
doi: 10.1103/fdcf-dkws
external_id:
arxiv:
- '2510.24536'
file:
- access_level: open_access
checksum: 99ef02dd741c4536eeefd12d409d5269
content_type: application/pdf
creator: dernst
date_created: 2026-02-24T06:57:44Z
date_updated: 2026-02-24T06:57:44Z
file_id: '21352'
file_name: 2026_PRXLife_Brueckner.pdf
file_size: 1147994
relation: main_file
success: 1
file_date_updated: 2026-02-24T06:57:44Z
has_accepted_license: '1'
intvolume: ' 4'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
project:
- _id: 7bfe6a29-9f16-11ee-852c-c0da5e2045d9
grant_number: '101118866'
name: 'Transcription in 4D: the dynamic interplay between chromatin architecture
and gene expression in developing pseudo-embryos'
publication: PRX Life
publication_identifier:
eissn:
- 2835-8279
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
status: public
title: 'Marr''s three levels for embryonic development: Information, dynamical systems,
gene networks'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 4
year: '2026'
...
---
OA_place: repository
OA_type: free access
_id: '21284'
abstract:
- lang: eng
text: The advantageous characteristics attributed to the 19F nucleus have made it
a popular target for NMR once again in recent years. Aside from solution NMR,
an increasing number of studies have been conducted applying solid-state magic-angle-spinning
NMR to fluorine-labeled samples. Here, the high chemical shift anisotropy and
strong dipolar couplings can be utilized to get structural insights into proteins
and measure long distances. Despite increasing popularity and promising benefits,
the sensitivity of biomolecular 19F MAS NMR often suffers from slow longitudinal
T1 relaxation and therefore long recycle delays. In this work, we expand paramagnetic
doping, an approach commonly used to reduce proton T1 relaxation times, to 19F-labeled
biological samples. We study the effect of Gd(DTPA) and Gd(DTPA-BMA) on 19F and
13C T1 and T2 relaxation in a [5-19F13C]-tryptophan-labeled protein via 19F-detected
MAS NMR experiments. The observed paramagnetic relaxation enhancement substantially
reduces measurement times of 19F MAS NMR experiments without compromising resolution.
Additionally, we report the chemical-shift assignments of all four fluorotryptophan
signals in the 12 × 39 kDa large protein using a mutagenesis approach.
acknowledged_ssus:
- _id: NMR
- _id: LifeSc
acknowledgement: We thank Ben P. Tatman for insightful discussions. This research
was supported by the Scientific Service Units (SSU) of Institute of Science and
Technology Austria (ISTA) through resources provided by the Nuclear Magnetic Resonance
Facility and the Lab Support Facility.
article_processing_charge: No
author:
- first_name: Lea Marie
full_name: Becker, Lea Marie
id: 36336939-eb97-11eb-a6c2-c83f1214ca79
last_name: Becker
orcid: 0000-0002-6401-5151
- first_name: Paul
full_name: Schanda, Paul
id: 7B541462-FAF6-11E9-A490-E8DFE5697425
last_name: Schanda
orcid: 0000-0002-9350-7606
citation:
ama: Becker LM, Schanda P. Research data for “Accelerated 19F biomolecular magic-angle
spinning NMR with paramagnetic dopants.” 2026. doi:10.15479/AT-ISTA-21284
apa: Becker, L. M., & Schanda, P. (2026). Research data for “Accelerated 19F
biomolecular magic-angle spinning NMR with paramagnetic dopants.” Institute of
Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-21284
chicago: Becker, Lea Marie, and Paul Schanda. “Research Data for ‘Accelerated 19F
Biomolecular Magic-Angle Spinning NMR with Paramagnetic Dopants.’” Institute of
Science and Technology Austria, 2026. https://doi.org/10.15479/AT-ISTA-21284.
ieee: L. M. Becker and P. Schanda, “Research data for ‘Accelerated 19F biomolecular
magic-angle spinning NMR with paramagnetic dopants.’” Institute of Science and
Technology Austria, 2026.
ista: Becker LM, Schanda P. 2026. Research data for ‘Accelerated 19F biomolecular
magic-angle spinning NMR with paramagnetic dopants’, Institute of Science and
Technology Austria, 10.15479/AT-ISTA-21284.
mla: Becker, Lea Marie, and Paul Schanda. Research Data for “Accelerated 19F
Biomolecular Magic-Angle Spinning NMR with Paramagnetic Dopants.” Institute
of Science and Technology Austria, 2026, doi:10.15479/AT-ISTA-21284.
short: L.M. Becker, P. Schanda, (2026).
contributor:
- contributor_type: researcher
first_name: Giorgia
id: 334a5e40-8747-11f0-b671-ba1f5154b4b4
last_name: Toscano
- contributor_type: researcher
first_name: Anna
id: 9fb2a840-89e1-11ee-a8b7-cc5c7ba62471
last_name: Kapitonova
- contributor_type: researcher
first_name: Rajkumar
id: a3089acd-6806-11ee-bacc-f0c7d500ad20
last_name: Singh
- contributor_type: researcher
first_name: Undina
id: bb74f472-ae54-11eb-9835-bc9c22fb1183
last_name: Guillerm
- contributor_type: researcher
first_name: Roman
last_name: Lichtenecker
corr_author: '1'
date_created: 2026-02-17T10:17:14Z
date_published: 2026-02-18T00:00:00Z
date_updated: 2026-02-18T10:12:49Z
day: '18'
ddc:
- '541'
department:
- _id: GradSch
- _id: PaSc
doi: 10.15479/AT-ISTA-21284
file:
- access_level: open_access
checksum: 2d3105f26be578073b88ee1f2ea0bdb1
content_type: application/zip
creator: lbecker
date_created: 2026-02-17T10:11:14Z
date_updated: 2026-02-17T10:11:14Z
file_id: '21285'
file_name: Research_data.zip
file_size: 36996027
relation: main_file
success: 1
- access_level: open_access
checksum: e24aebcdb8856cb181cbaa02de020ddb
content_type: text/plain
creator: lbecker
date_created: 2026-02-17T10:11:14Z
date_updated: 2026-02-17T10:11:14Z
file_id: '21286'
file_name: README.txt
file_size: 1993
relation: table_of_contents
file_date_updated: 2026-02-17T10:11:14Z
has_accepted_license: '1'
month: '2'
oa: 1
oa_version: None
publisher: Institute of Science and Technology Austria
status: public
title: Research data for "Accelerated 19F biomolecular magic-angle spinning NMR with
paramagnetic dopants"
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: research_data
user_id: 68b8ca59-c5b3-11ee-8790-cd641c68093d
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '21290'
abstract:
- lang: eng
text: Gene duplication underlies evolutionary innovation, yet many paralogues remain
highly similar, raising questions about their functional divergence and physiological
relevance. The spliceosomal Sm core protein SNRPB and its mammalian-specific paralogue
SNRPN share over 90% sequence identity, but their distinct expression patterns
- SNRPB being ubiquitous and SNRPN confined to the brain - suggest specialized
functions. Why mammals have two different spliceosomes has remained obscure. Here,
we generated isogenic human cell lines expressing ectopically either SNRPB or
SNRPN exclusively and found that SNRPN stabilizes transcripts involved in energy
metabolism and mitochondrial function, leading to increased mitochondrial abundance
and oxygen consumption. Despite similar spliceosomal interactomes, SNRPN more
strongly associates with the PRMT5 methylosome complex and exhibits dynamic arginine
methylation in its C-terminal region that is sensitive to translation inhibition
and amino acid availability. The SNRPN-dependent transcriptome responds to translation
inhibition by stabilizing long, intron-rich genes involved in amino acid and energy
metabolism. Our findings reveal a nutrient-sensitive, methylation-dependent mechanism
that differentiates the two paralogues. This suggests that SNRPN functions as
a metabolic-specialized spliceosomal subunit thereby providing tissue-specific
adaptation of RNA processing in mammals.
acknowledgement: "We thank Oliver Mühlemann and Alex Hofer (University of Bern) for
sharing SMG inhibitors\r\nand for their expertise in nonsense-mediated mRNA decay
and Maria Hondele for critical\r\nreading of the manuscript draft. We also thank
the IMB Genomics Core Facility for assistance\r\nwith library preparation and sequencing,
Martin Möckel and the IMB Protein Production Core\r\nFacility for providing enzymes
used in this work, Marton Gelleri together with the IMB\r\nMicroscopy Core Facility
for support with microscopy and FRAP experiments, Jasmin Cartano\r\nfor proteomics
sample processing and the IMB Flow Cytometry Core Facility for support. In\r\naddition,
we thank the Imaging Core Facility (IMCF) and the FACS Core Facility at the\r\nBiozentrum,
University of Basel, for technical assistance. CIKV acknowledges funding by the\r\nDeutsche
Forschungsgemeinschaft (DFG, German Research Foundation) - Individual Grant\r\nProject
no. 513744403, Scientific Network Grant Project no. 531902894, GRK2526 “Genevo”\r\n-
Project no. 407023052”, GRK2859 (“4R”) - Project no. 491145305, Forschungsinitiative\r\nRheinland-Pfalz
(ReALity), the EMBO Young Investigator Program (5795), institutional\r\nfunding
from the Institute of Molecular Biology and funds from the Kanton Basel-Stadt and\r\nBasel-Land
provided to the Biozentrum of the University Basel. J.H.G.F.G. was part of the\r\n‘Science
of Healthy Ageing Research Programme’ (SHARP) initiative funded by RhinelandPalatinate’s
Ministry of Science, Education and Culture. PR is funded by the Biozentrum PhD\r\nFellowships
Program. MFB received financial support from the intramural High Potentials\r\nGrant
program of the University Medical Center Mainz, Forschungsinitiative Rheinland-Pfalz\r\n(ReALity)
and Stiftungen zugunsten der Medizinischen Fakultät der LMU Klinikum (26069).\r\nInstruments
in the IMB core facilities were supported by funds from the DFG: Laser Scanning\r\nConfocal
(Leica Stellaris 8 Falcon, funded by the DFG - Project #497669232), Orbitrap Astral
system (funded by the DFG - Project #524805621) and BD LSRFortessa SOPR is funded
by\r\nthe DFG - Project #210253511.\r\n"
article_processing_charge: No
author:
- first_name: Feyza
full_name: Polat Haas, Feyza
last_name: Polat Haas
- first_name: Ana
full_name: Villalba Requena, Ana
id: 68cb85a0-39f7-11eb-9559-9aaab4f6a247
last_name: Villalba Requena
orcid: 0000-0002-5615-5277
- first_name: Polina
full_name: Rusina, Polina
last_name: Rusina
- first_name: Anusha
full_name: Gopalan, Anusha
last_name: Gopalan
- first_name: Hector
full_name: Fritz, Hector
last_name: Fritz
- first_name: Azamat
full_name: Akhmetkaliyev, Azamat
last_name: Akhmetkaliyev
- first_name: Frank
full_name: Ruehle, Frank
last_name: Ruehle
- first_name: Anna
full_name: Einsiedel, Anna
last_name: Einsiedel
- first_name: Anna
full_name: Szczepinska, Anna
last_name: Szczepinska
- first_name: Fridolin
full_name: Kielisch, Fridolin
last_name: Kielisch
- first_name: Jia-Xuan
full_name: Chen, Jia-Xuan
last_name: Chen
- first_name: Susanne
full_name: Nguyen, Susanne
last_name: Nguyen
- first_name: Thierry
full_name: Schmidlin, Thierry
last_name: Schmidlin
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
- first_name: M. Felicia
full_name: Bailicata, M. Felicia
last_name: Bailicata
- first_name: Claudia Isabelle
full_name: Keller Valsecchi, Claudia Isabelle
last_name: Keller Valsecchi
citation:
ama: Polat Haas F, Villalba Requena A, Rusina P, et al. The splicing paralogues
SNRPB and SNRPN control differential metabolic states. bioRxiv. doi:10.64898/2026.02.11.705284
apa: Polat Haas, F., Villalba Requena, A., Rusina, P., Gopalan, A., Fritz, H., Akhmetkaliyev,
A., … Keller Valsecchi, C. I. (n.d.). The splicing paralogues SNRPB and SNRPN
control differential metabolic states. bioRxiv. https://doi.org/10.64898/2026.02.11.705284
chicago: Polat Haas, Feyza, Ana Villalba Requena, Polina Rusina, Anusha Gopalan,
Hector Fritz, Azamat Akhmetkaliyev, Frank Ruehle, et al. “The Splicing Paralogues
SNRPB and SNRPN Control Differential Metabolic States.” BioRxiv, n.d. https://doi.org/10.64898/2026.02.11.705284.
ieee: F. Polat Haas et al., “The splicing paralogues SNRPB and SNRPN control
differential metabolic states.,” bioRxiv. .
ista: Polat Haas F, Villalba Requena A, Rusina P, Gopalan A, Fritz H, Akhmetkaliyev
A, Ruehle F, Einsiedel A, Szczepinska A, Kielisch F, Chen J-X, Nguyen S, Schmidlin
T, Hippenmeyer S, Bailicata MF, Keller Valsecchi CI. The splicing paralogues SNRPB
and SNRPN control differential metabolic states. bioRxiv, 10.64898/2026.02.11.705284.
mla: Polat Haas, Feyza, et al. “The Splicing Paralogues SNRPB and SNRPN Control
Differential Metabolic States.” BioRxiv, doi:10.64898/2026.02.11.705284.
short: F. Polat Haas, A. Villalba Requena, P. Rusina, A. Gopalan, H. Fritz, A. Akhmetkaliyev,
F. Ruehle, A. Einsiedel, A. Szczepinska, F. Kielisch, J.-X. Chen, S. Nguyen, T.
Schmidlin, S. Hippenmeyer, M.F. Bailicata, C.I. Keller Valsecchi, BioRxiv (n.d.).
date_created: 2026-02-17T11:35:59Z
date_published: 2026-02-11T00:00:00Z
date_updated: 2026-02-23T11:03:33Z
day: '11'
department:
- _id: SiHi
doi: 10.64898/2026.02.11.705284
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.64898/2026.02.11.705284
month: '02'
oa: 1
oa_version: Preprint
publication: bioRxiv
publication_status: submitted
status: public
title: The splicing paralogues SNRPB and SNRPN control differential metabolic states.
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21295'
abstract:
- lang: eng
text: 'Depending on the type of flow, the transition to turbulence can take one
of two forms: either turbulence arises from a sequence of instabilities or from
the spatial proliferation of transiently chaotic domains, a process analogous
to directed percolation. The former scenario is commonly referred to as a supercritical
transition and frequently encountered in flows destabilized by body forces, whereas
the latter subcritical transition is common in shear flows. Both cases are inherently
continuous in a sense that the transformation from ordered laminar to fully turbulent
fluid motion is only accomplished gradually with flow speed. Here we show that
these established transition types do not account for the more general setting
of shear flows subject to body forces. The combination of the two continuous scenarios
leads to the attenuation of spatial coupling; with increasing forcing amplitude,
the transition becomes increasingly sharp and eventually discontinuous. We argue
that the suppression of laminar–turbulent coexistence and the approach towards
a discontinuous phase transition potentially apply to a broad range of situations
including flows subject to, for example, buoyancy, centrifugal or electromagnetic
forces.'
acknowledgement: The work was supported by the Simons Foundation (grant number 662960,
to B.H.). Open access funding provided by Institute of Science and Technology (IST
Austria).
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Bowen
full_name: Yang, Bowen
id: 71b6ff4b-15b2-11ec-abd3-aef6b028cf7e
last_name: Yang
orcid: 0000-0002-4843-6853
- first_name: Yi
full_name: Zhuang, Yi
id: 3677B57C-F248-11E8-B48F-1D18A9856A87
last_name: Zhuang
- first_name: Gökhan
full_name: Yalniz, Gökhan
id: 66E74FA2-D8BF-11E9-8249-8DE2E5697425
last_name: Yalniz
orcid: 0000-0002-8490-9312
- first_name: Mukund
full_name: Vasudevan, Mukund
id: 3C5A959A-F248-11E8-B48F-1D18A9856A87
last_name: Vasudevan
- first_name: Elena
full_name: Marensi, Elena
id: 0BE7553A-1004-11EA-B805-18983DDC885E
last_name: Marensi
orcid: 0000-0001-7173-4923
- first_name: Björn
full_name: Hof, Björn
id: 3A374330-F248-11E8-B48F-1D18A9856A87
last_name: Hof
orcid: 0000-0003-2057-2754
citation:
ama: Yang B, Zhuang Y, Yalniz G, Vasudevan M, Marensi E, Hof B. Discontinuous transition
to shear flow turbulence. Nature Physics. 2026. doi:10.1038/s41567-025-03166-3
apa: Yang, B., Zhuang, Y., Yalniz, G., Vasudevan, M., Marensi, E., & Hof, B.
(2026). Discontinuous transition to shear flow turbulence. Nature Physics.
Springer Nature. https://doi.org/10.1038/s41567-025-03166-3
chicago: Yang, Bowen, Yi Zhuang, Gökhan Yalniz, Mukund Vasudevan, Elena Marensi,
and Björn Hof. “Discontinuous Transition to Shear Flow Turbulence.” Nature
Physics. Springer Nature, 2026. https://doi.org/10.1038/s41567-025-03166-3.
ieee: B. Yang, Y. Zhuang, G. Yalniz, M. Vasudevan, E. Marensi, and B. Hof, “Discontinuous
transition to shear flow turbulence,” Nature Physics. Springer Nature,
2026.
ista: Yang B, Zhuang Y, Yalniz G, Vasudevan M, Marensi E, Hof B. 2026. Discontinuous
transition to shear flow turbulence. Nature Physics.
mla: Yang, Bowen, et al. “Discontinuous Transition to Shear Flow Turbulence.” Nature
Physics, Springer Nature, 2026, doi:10.1038/s41567-025-03166-3.
short: B. Yang, Y. Zhuang, G. Yalniz, M. Vasudevan, E. Marensi, B. Hof, Nature Physics
(2026).
corr_author: '1'
date_created: 2026-02-17T11:38:41Z
date_published: 2026-02-17T00:00:00Z
date_updated: 2026-02-23T11:36:46Z
day: '17'
ddc:
- '532'
department:
- _id: GradSch
- _id: BjHo
doi: 10.1038/s41567-025-03166-3
external_id:
arxiv:
- '2311.11474'
has_accepted_license: '1'
language:
- iso: eng
month: '02'
oa_version: Published Version
project:
- _id: 238598C6-32DE-11EA-91FC-C7463DDC885E
grant_number: '662960'
name: Revisiting the Turbulence Problem Using Statistical Mechanics
publication: Nature Physics
publication_identifier:
eissn:
- 1745-2481
issn:
- 1745-2473
publication_status: epub_ahead
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Discontinuous transition to shear flow turbulence
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...