--- OA_type: free access _id: '9298' abstract: - lang: eng text: 'In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field. ' acknowledgement: This work was supported by the National Institute of General Medical Sciences [GM131919]. Due to space and other limitations, it is not possible to include all other sources of financial support. article_processing_charge: No article_type: review author: - first_name: Daniel J. full_name: Klionsky, Daniel J. last_name: Klionsky - first_name: Amal Kamal full_name: Abdel-Aziz, Amal Kamal last_name: Abdel-Aziz - first_name: Sara full_name: Abdelfatah, Sara last_name: Abdelfatah - first_name: Mahmoud full_name: Abdellatif, Mahmoud last_name: Abdellatif - first_name: Asghar full_name: Abdoli, Asghar last_name: Abdoli - first_name: Steffen full_name: Abel, Steffen last_name: Abel - first_name: Hagai full_name: Abeliovich, Hagai last_name: Abeliovich - first_name: Marie H. full_name: Abildgaard, Marie H. last_name: Abildgaard - first_name: Yakubu Princely full_name: Abudu, Yakubu Princely last_name: Abudu - first_name: Abraham full_name: Acevedo-Arozena, Abraham last_name: Acevedo-Arozena - first_name: Iannis E. full_name: Adamopoulos, Iannis E. last_name: Adamopoulos - first_name: Khosrow full_name: Adeli, Khosrow last_name: Adeli - first_name: Timon E. full_name: Adolph, Timon E. last_name: Adolph - first_name: Annagrazia full_name: Adornetto, Annagrazia last_name: Adornetto - first_name: Elma full_name: Aflaki, Elma last_name: Aflaki - first_name: Galila full_name: Agam, Galila last_name: Agam - first_name: Anupam full_name: Agarwal, Anupam last_name: Agarwal - first_name: Bharat B. full_name: Aggarwal, Bharat B. last_name: Aggarwal - first_name: Maria full_name: Agnello, Maria last_name: Agnello - first_name: Patrizia full_name: Agostinis, Patrizia last_name: Agostinis - first_name: Javed N. full_name: Agrewala, Javed N. last_name: Agrewala - first_name: Alexander full_name: Agrotis, Alexander last_name: Agrotis - first_name: Patricia V. full_name: Aguilar, Patricia V. last_name: Aguilar - first_name: S. 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Isabel last_name: Burón - first_name: Victor full_name: Bustos, Victor last_name: Bustos - first_name: Sabrina full_name: Büttner, Sabrina last_name: Büttner - first_name: Elena full_name: Butturini, Elena last_name: Butturini - first_name: Aaron full_name: Byrd, Aaron last_name: Byrd - first_name: Isabel full_name: Cabas, Isabel last_name: Cabas - first_name: Sandra full_name: Cabrera-Benitez, Sandra last_name: Cabrera-Benitez - first_name: Ken full_name: Cadwell, Ken last_name: Cadwell - first_name: Jingjing full_name: Cai, Jingjing last_name: Cai - first_name: Lu full_name: Cai, Lu last_name: Cai - first_name: Qian full_name: Cai, Qian last_name: Cai - first_name: Montserrat full_name: Cairó, Montserrat last_name: Cairó - first_name: Jose A. full_name: Calbet, Jose A. last_name: Calbet - first_name: Guy A. full_name: Caldwell, Guy A. last_name: Caldwell - first_name: Kim A. full_name: Caldwell, Kim A. last_name: Caldwell - first_name: Jarrod A. full_name: Call, Jarrod A. last_name: Call - first_name: Riccardo full_name: Calvani, Riccardo last_name: Calvani - first_name: Ana C. full_name: Calvo, Ana C. last_name: Calvo - first_name: Miguel full_name: Calvo-Rubio Barrera, Miguel last_name: Calvo-Rubio Barrera - first_name: Niels O.S. full_name: Camara, Niels O.S. last_name: Camara - first_name: Jacques H. full_name: Camonis, Jacques H. last_name: Camonis - first_name: Nadine full_name: Camougrand, Nadine last_name: Camougrand - first_name: Michelangelo full_name: Campanella, Michelangelo last_name: Campanella - first_name: Edward M. full_name: Campbell, Edward M. last_name: Campbell - first_name: François Xavier full_name: Campbell-Valois, François Xavier last_name: Campbell-Valois - first_name: Silvia full_name: Campello, Silvia last_name: Campello - first_name: Ilaria full_name: Campesi, Ilaria last_name: Campesi - first_name: Juliane C. full_name: Campos, Juliane C. last_name: Campos - first_name: Olivier full_name: Camuzard, Olivier last_name: Camuzard - first_name: Jorge full_name: Cancino, Jorge last_name: Cancino - first_name: Danilo full_name: Candido De Almeida, Danilo last_name: Candido De Almeida - first_name: Laura full_name: Canesi, Laura last_name: Canesi - first_name: Isabella full_name: Caniggia, Isabella last_name: Caniggia - first_name: Barbara full_name: Canonico, Barbara last_name: Canonico - first_name: Carles full_name: Cantí, Carles last_name: Cantí - first_name: Bin full_name: Cao, Bin last_name: Cao - first_name: Michele full_name: Caraglia, Michele last_name: Caraglia - first_name: Beatriz full_name: Caramés, Beatriz last_name: Caramés - first_name: Evie H. full_name: Carchman, Evie H. last_name: Carchman - first_name: Elena full_name: Cardenal-Muñoz, Elena last_name: Cardenal-Muñoz - first_name: Cesar full_name: Cardenas, Cesar last_name: Cardenas - first_name: Luis full_name: Cardenas, Luis last_name: Cardenas - first_name: Sandra M. full_name: Cardoso, Sandra M. last_name: Cardoso - first_name: Jennifer S. full_name: Carew, Jennifer S. last_name: Carew - first_name: Georges F. full_name: Carle, Georges F. last_name: Carle - first_name: Gillian full_name: Carleton, Gillian last_name: Carleton - first_name: Silvia full_name: Carloni, Silvia last_name: Carloni - first_name: Didac full_name: Carmona-Gutierrez, Didac last_name: Carmona-Gutierrez - first_name: Leticia A. full_name: Carneiro, Leticia A. last_name: Carneiro - first_name: Oliana full_name: Carnevali, Oliana last_name: Carnevali - first_name: Julian M. full_name: Carosi, Julian M. last_name: Carosi - first_name: Serena full_name: Carra, Serena last_name: Carra - first_name: Alice full_name: Carrier, Alice last_name: Carrier - first_name: Lucie full_name: Carrier, Lucie last_name: Carrier - first_name: Bernadette full_name: Carroll, Bernadette last_name: Carroll - first_name: A. 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Brent last_name: Carter - first_name: Andreia Neves full_name: Carvalho, Andreia Neves last_name: Carvalho - first_name: Magali full_name: Casanova, Magali last_name: Casanova - first_name: Caty full_name: Casas, Caty last_name: Casas - first_name: Josefina full_name: Casas, Josefina last_name: Casas - first_name: Chiara full_name: Cassioli, Chiara last_name: Cassioli - first_name: Eliseo F. full_name: Castillo, Eliseo F. last_name: Castillo - first_name: Karen full_name: Castillo, Karen last_name: Castillo - first_name: Sonia full_name: Castillo-Lluva, Sonia last_name: Castillo-Lluva - first_name: Francesca full_name: Castoldi, Francesca last_name: Castoldi - first_name: Marco full_name: Castori, Marco last_name: Castori - first_name: Ariel F. full_name: Castro, Ariel F. last_name: Castro - first_name: Margarida full_name: Castro-Caldas, Margarida last_name: Castro-Caldas - first_name: Javier full_name: Castro-Hernandez, Javier last_name: Castro-Hernandez - first_name: Susana full_name: Castro-Obregon, Susana last_name: Castro-Obregon - first_name: Sergio D. full_name: Catz, Sergio D. last_name: Catz - first_name: Claudia full_name: Cavadas, Claudia last_name: Cavadas - first_name: Federica full_name: Cavaliere, Federica last_name: Cavaliere - first_name: Gabriella full_name: Cavallini, Gabriella last_name: Cavallini - first_name: Maria full_name: Cavinato, Maria last_name: Cavinato - first_name: Maria L. full_name: Cayuela, Maria L. last_name: Cayuela - first_name: Paula full_name: Cebollada Rica, Paula last_name: Cebollada Rica - first_name: Valentina full_name: Cecarini, Valentina last_name: Cecarini - first_name: Francesco full_name: Cecconi, Francesco last_name: Cecconi - first_name: Marzanna full_name: Cechowska-Pasko, Marzanna last_name: Cechowska-Pasko - first_name: Simone full_name: Cenci, Simone last_name: Cenci - first_name: Victòria full_name: Ceperuelo-Mallafré, Victòria last_name: Ceperuelo-Mallafré - first_name: João J. full_name: Cerqueira, João J. last_name: Cerqueira - first_name: Janete M. full_name: Cerutti, Janete M. last_name: Cerutti - first_name: Davide full_name: Cervia, Davide last_name: Cervia - first_name: Vildan Bozok full_name: Cetintas, Vildan Bozok last_name: Cetintas - first_name: Silvia full_name: Cetrullo, Silvia last_name: Cetrullo - first_name: Han Jung full_name: Chae, Han Jung last_name: Chae - first_name: Andrei S. full_name: Chagin, Andrei S. last_name: Chagin - first_name: Chee Yin full_name: Chai, Chee Yin last_name: Chai - first_name: Gopal full_name: Chakrabarti, Gopal last_name: Chakrabarti - first_name: Oishee full_name: Chakrabarti, Oishee last_name: Chakrabarti - first_name: Tapas full_name: Chakraborty, Tapas last_name: Chakraborty - first_name: Trinad full_name: Chakraborty, Trinad last_name: Chakraborty - first_name: Mounia full_name: Chami, Mounia last_name: Chami - first_name: Georgios full_name: Chamilos, Georgios last_name: Chamilos - first_name: David W. full_name: Chan, David W. last_name: Chan - first_name: Edmond Y.W. full_name: Chan, Edmond Y.W. last_name: Chan - first_name: Edward D. full_name: Chan, Edward D. last_name: Chan - first_name: H. 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first_name: Santosh full_name: Chauhan, Santosh last_name: Chauhan - first_name: Edward full_name: Chaum, Edward last_name: Chaum - first_name: Frédéric full_name: Checler, Frédéric last_name: Checler - first_name: Michael E. full_name: Cheetham, Michael E. last_name: Cheetham - first_name: Chang Shi full_name: Chen, Chang Shi last_name: Chen - first_name: Guang Chao full_name: Chen, Guang Chao last_name: Chen - first_name: Jian Fu full_name: Chen, Jian Fu last_name: Chen - first_name: Liam L. full_name: Chen, Liam L. last_name: Chen - first_name: Leilei full_name: Chen, Leilei last_name: Chen - first_name: Lin full_name: Chen, Lin last_name: Chen - first_name: Mingliang full_name: Chen, Mingliang last_name: Chen - first_name: Mu Kuan full_name: Chen, Mu Kuan last_name: Chen - first_name: Ning full_name: Chen, Ning last_name: Chen - first_name: Quan full_name: Chen, Quan last_name: Chen - first_name: Ruey Hwa full_name: Chen, Ruey Hwa last_name: Chen - first_name: Shi full_name: Chen, Shi last_name: Chen - first_name: Wei full_name: Chen, Wei last_name: Chen - first_name: Weiqiang full_name: Chen, Weiqiang last_name: Chen - first_name: Xin Ming full_name: Chen, Xin Ming last_name: Chen - first_name: Xiong Wen full_name: Chen, Xiong Wen last_name: Chen - first_name: Xu full_name: Chen, Xu id: 4E5ADCAA-F248-11E8-B48F-1D18A9856A87 last_name: Chen - first_name: Yan full_name: Chen, Yan last_name: Chen - first_name: Ye Guang full_name: Chen, Ye Guang last_name: Chen - first_name: Yingyu full_name: Chen, Yingyu last_name: Chen - first_name: Yongqiang full_name: Chen, Yongqiang last_name: Chen - first_name: Yu Jen full_name: Chen, Yu Jen last_name: Chen - first_name: Yue Qin full_name: Chen, Yue Qin last_name: Chen - first_name: Zhefan Stephen full_name: Chen, Zhefan Stephen last_name: Chen - first_name: Zhi full_name: Chen, Zhi last_name: Chen - first_name: Zhi Hua full_name: Chen, Zhi Hua last_name: Chen - first_name: Zhijian J. full_name: Chen, Zhijian J. last_name: Chen - first_name: Zhixiang full_name: Chen, Zhixiang last_name: Chen - first_name: Hanhua full_name: Cheng, Hanhua last_name: Cheng - first_name: Jun full_name: Cheng, Jun last_name: Cheng - first_name: Shi Yuan full_name: Cheng, Shi Yuan last_name: Cheng - first_name: Wei full_name: Cheng, Wei last_name: Cheng - first_name: Xiaodong full_name: Cheng, Xiaodong last_name: Cheng - first_name: Xiu Tang full_name: Cheng, Xiu Tang last_name: Cheng - first_name: Yiyun full_name: Cheng, Yiyun last_name: Cheng - first_name: Zhiyong full_name: Cheng, Zhiyong last_name: Cheng - first_name: Zhong full_name: Chen, Zhong last_name: Chen - first_name: Heesun full_name: Cheong, Heesun last_name: Cheong - first_name: Jit Kong full_name: Cheong, Jit Kong last_name: Cheong - first_name: Boris V. full_name: Chernyak, Boris V. last_name: Chernyak - first_name: Sara full_name: Cherry, Sara last_name: Cherry - first_name: Chi Fai Randy full_name: Cheung, Chi Fai Randy last_name: Cheung - first_name: Chun Hei Antonio full_name: Cheung, Chun Hei Antonio last_name: Cheung - first_name: King Ho full_name: Cheung, King Ho last_name: Cheung - first_name: Eric full_name: Chevet, Eric last_name: Chevet - first_name: Richard J. full_name: Chi, Richard J. last_name: Chi - first_name: Alan Kwok Shing full_name: Chiang, Alan Kwok Shing last_name: Chiang - first_name: Ferdinando full_name: Chiaradonna, Ferdinando last_name: Chiaradonna - first_name: Roberto full_name: Chiarelli, Roberto last_name: Chiarelli - first_name: Mario full_name: Chiariello, Mario last_name: Chiariello - first_name: Nathalia full_name: Chica, Nathalia last_name: Chica - first_name: Susanna full_name: Chiocca, Susanna last_name: Chiocca - first_name: Mario full_name: Chiong, Mario last_name: Chiong - first_name: Shih Hwa full_name: Chiou, Shih Hwa last_name: Chiou - first_name: Abhilash I. full_name: Chiramel, Abhilash I. last_name: Chiramel - first_name: Valerio full_name: Chiurchiù, Valerio last_name: Chiurchiù - first_name: Dong Hyung full_name: Cho, Dong Hyung last_name: Cho - first_name: Seong Kyu full_name: Choe, Seong Kyu last_name: Choe - first_name: Augustine M.K. full_name: Choi, Augustine M.K. last_name: Choi - first_name: Mary E. full_name: Choi, Mary E. last_name: Choi - first_name: Kamalika Roy full_name: Choudhury, Kamalika Roy last_name: Choudhury - first_name: Norman S. full_name: Chow, Norman S. last_name: Chow - first_name: Charleen T. full_name: Chu, Charleen T. last_name: Chu - first_name: Jason P. full_name: Chua, Jason P. last_name: Chua - first_name: John Jia En full_name: Chua, John Jia En last_name: Chua - first_name: Hyewon full_name: Chung, Hyewon last_name: Chung - first_name: Kin Pan full_name: Chung, Kin Pan last_name: Chung - first_name: Seockhoon full_name: Chung, Seockhoon last_name: Chung - first_name: So Hyang full_name: Chung, So Hyang last_name: Chung - first_name: Yuen Li full_name: Chung, Yuen Li last_name: Chung - first_name: Valentina full_name: Cianfanelli, Valentina last_name: Cianfanelli - first_name: Iwona A. full_name: Ciechomska, Iwona A. last_name: Ciechomska - first_name: Mariana full_name: Cifuentes, Mariana last_name: Cifuentes - first_name: Laura full_name: Cinque, Laura last_name: Cinque - 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first_name: Dale P. full_name: Corkery, Dale P. last_name: Corkery - first_name: Nils full_name: Cordes, Nils last_name: Cordes - first_name: Katia full_name: Cortese, Katia last_name: Cortese - first_name: Maria Do Carmo full_name: Costa, Maria Do Carmo last_name: Costa - first_name: Sarah full_name: Costantino, Sarah last_name: Costantino - first_name: Paola full_name: Costelli, Paola last_name: Costelli - first_name: Ana full_name: Coto-Montes, Ana last_name: Coto-Montes - first_name: Peter J. full_name: Crack, Peter J. last_name: Crack - first_name: Jose L. full_name: Crespo, Jose L. last_name: Crespo - first_name: Alfredo full_name: Criollo, Alfredo last_name: Criollo - first_name: Valeria full_name: Crippa, Valeria last_name: Crippa - first_name: Riccardo full_name: Cristofani, Riccardo last_name: Cristofani - first_name: Tamas full_name: Csizmadia, Tamas last_name: Csizmadia - first_name: Antonio full_name: Cuadrado, Antonio last_name: Cuadrado - first_name: Bing full_name: Cui, Bing last_name: Cui - 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first_name: Chiara full_name: De Leonibus, Chiara last_name: De Leonibus - first_name: Mayara G. full_name: De Mattos Barbosa, Mayara G. last_name: De Mattos Barbosa - first_name: Guido R.Y. full_name: De Meyer, Guido R.Y. last_name: De Meyer - first_name: Angelo full_name: De Milito, Angelo last_name: De Milito - first_name: Cosimo full_name: De Nunzio, Cosimo last_name: De Nunzio - first_name: Clara full_name: De Palma, Clara last_name: De Palma - first_name: Mauro full_name: De Santi, Mauro last_name: De Santi - first_name: Claudio full_name: De Virgilio, Claudio last_name: De Virgilio - first_name: Daniela full_name: De Zio, Daniela last_name: De Zio - first_name: Jayanta full_name: Debnath, Jayanta last_name: Debnath - first_name: Brian J. full_name: Debosch, Brian J. last_name: Debosch - first_name: Jean Paul full_name: Decuypere, Jean Paul last_name: Decuypere - first_name: Mark A. full_name: Deehan, Mark A. last_name: Deehan - first_name: Gianluca full_name: Deflorian, Gianluca last_name: Deflorian - first_name: James full_name: Degregori, James last_name: Degregori - first_name: Benjamin full_name: Dehay, Benjamin last_name: Dehay - first_name: Gabriel full_name: Del Rio, Gabriel last_name: Del Rio - first_name: Joe R. full_name: Delaney, Joe R. last_name: Delaney - first_name: Lea M.D. full_name: Delbridge, Lea M.D. last_name: Delbridge - first_name: Elizabeth full_name: Delorme-Axford, Elizabeth last_name: Delorme-Axford - first_name: M. 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first_name: Grant full_name: Dewson, Grant last_name: Dewson - first_name: Mahendiran full_name: Dharmasivam, Mahendiran last_name: Dharmasivam - first_name: Rohan full_name: Dhiman, Rohan last_name: Dhiman - first_name: Diego full_name: Di Bernardo, Diego last_name: Di Bernardo - first_name: Manlio full_name: Di Cristina, Manlio last_name: Di Cristina - first_name: Fabio full_name: Di Domenico, Fabio last_name: Di Domenico - first_name: Pietro full_name: Di Fazio, Pietro last_name: Di Fazio - first_name: Alessio full_name: Di Fonzo, Alessio last_name: Di Fonzo - first_name: Giovanni full_name: Di Guardo, Giovanni last_name: Di Guardo - first_name: Gianni M. full_name: Di Guglielmo, Gianni M. last_name: Di Guglielmo - first_name: Luca full_name: Di Leo, Luca last_name: Di Leo - first_name: Chiara full_name: Di Malta, Chiara last_name: Di Malta - first_name: Alessia full_name: Di Nardo, Alessia last_name: Di Nardo - first_name: Martina full_name: Di Rienzo, Martina last_name: Di Rienzo - first_name: Federica full_name: Di Sano, Federica last_name: Di Sano - first_name: George full_name: Diallinas, George last_name: Diallinas - first_name: Jiajie full_name: Diao, Jiajie last_name: Diao - first_name: Guillermo full_name: Diaz-Araya, Guillermo last_name: Diaz-Araya - first_name: Inés full_name: Díaz-Laviada, Inés last_name: Díaz-Laviada - first_name: Jared M. full_name: Dickinson, Jared M. last_name: Dickinson - first_name: Marc full_name: Diederich, Marc last_name: Diederich - first_name: Mélanie full_name: Dieudé, Mélanie last_name: Dieudé - first_name: Ivan full_name: Dikic, Ivan last_name: Dikic - first_name: Shiping full_name: Ding, Shiping last_name: Ding - first_name: Wen Xing full_name: Ding, Wen Xing last_name: Ding - first_name: Luciana full_name: Dini, Luciana last_name: Dini - first_name: Jelena full_name: Dinić, Jelena last_name: Dinić - first_name: Miroslav full_name: Dinic, Miroslav last_name: Dinic - first_name: Albena T. full_name: Dinkova-Kostova, Albena T. last_name: Dinkova-Kostova - first_name: Marc S. full_name: Dionne, Marc S. last_name: Dionne - first_name: Jörg H.W. full_name: Distler, Jörg H.W. last_name: Distler - first_name: Abhinav full_name: Diwan, Abhinav last_name: Diwan - first_name: Ian M.C. full_name: Dixon, Ian M.C. last_name: Dixon - first_name: Mojgan full_name: Djavaheri-Mergny, Mojgan last_name: Djavaheri-Mergny - first_name: Ina full_name: Dobrinski, Ina last_name: Dobrinski - first_name: Oxana full_name: Dobrovinskaya, Oxana last_name: Dobrovinskaya - first_name: Radek full_name: Dobrowolski, Radek last_name: Dobrowolski - first_name: Renwick C.J. full_name: Dobson, Renwick C.J. last_name: Dobson - first_name: Jelena full_name: Đokić, Jelena last_name: Đokić - first_name: Serap full_name: Dokmeci Emre, Serap last_name: Dokmeci Emre - first_name: Massimo full_name: Donadelli, Massimo last_name: Donadelli - first_name: Bo full_name: Dong, Bo last_name: Dong - first_name: Xiaonan full_name: Dong, Xiaonan last_name: Dong - first_name: Zhiwu full_name: Dong, Zhiwu last_name: Dong - first_name: Gerald W. full_name: Dorn, Gerald W. last_name: Dorn - first_name: Volker full_name: Dotsch, Volker last_name: Dotsch - first_name: Huan full_name: Dou, Huan last_name: Dou - first_name: Juan full_name: Dou, Juan last_name: Dou - first_name: Moataz full_name: Dowaidar, Moataz last_name: Dowaidar - first_name: Sami full_name: Dridi, Sami last_name: Dridi - first_name: Liat full_name: Drucker, Liat last_name: Drucker - first_name: Ailian full_name: Du, Ailian last_name: Du - first_name: Caigan full_name: Du, Caigan last_name: Du - first_name: Guangwei full_name: Du, Guangwei last_name: Du - first_name: Hai Ning full_name: Du, Hai Ning last_name: Du - first_name: Li Lin full_name: Du, Li Lin last_name: Du - first_name: André full_name: Du Toit, André last_name: Du Toit - first_name: Shao Bin full_name: Duan, Shao Bin last_name: Duan - first_name: Xiaoqiong full_name: Duan, Xiaoqiong last_name: Duan - first_name: Sónia P. full_name: Duarte, Sónia P. last_name: Duarte - first_name: Anna full_name: Dubrovska, Anna last_name: Dubrovska - first_name: Elaine A. full_name: Dunlop, Elaine A. last_name: Dunlop - first_name: Nicolas full_name: Dupont, Nicolas last_name: Dupont - first_name: Raúl V. full_name: Durán, Raúl V. last_name: Durán - first_name: Bilikere S. full_name: Dwarakanath, Bilikere S. last_name: Dwarakanath - first_name: Sergey A. full_name: Dyshlovoy, Sergey A. last_name: Dyshlovoy - first_name: Darius full_name: Ebrahimi-Fakhari, Darius last_name: Ebrahimi-Fakhari - first_name: Leopold full_name: Eckhart, Leopold last_name: Eckhart - first_name: Charles L. full_name: Edelstein, Charles L. last_name: Edelstein - first_name: Thomas full_name: Efferth, Thomas last_name: Efferth - first_name: Eftekhar full_name: Eftekharpour, Eftekhar last_name: Eftekharpour - first_name: Ludwig full_name: Eichinger, Ludwig last_name: Eichinger - first_name: Nabil full_name: Eid, Nabil last_name: Eid - first_name: Tobias full_name: Eisenberg, Tobias last_name: Eisenberg - first_name: N. 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first_name: Jiachun full_name: Feng, Jiachun last_name: Feng - first_name: Lifeng full_name: Feng, Lifeng last_name: Feng - first_name: Yibin full_name: Feng, Yibin last_name: Feng - first_name: Yuchen full_name: Feng, Yuchen last_name: Feng - first_name: Wei full_name: Feng, Wei last_name: Feng - first_name: Thais full_name: Fenz Araujo, Thais last_name: Fenz Araujo - first_name: Thomas A. full_name: Ferguson, Thomas A. last_name: Ferguson - first_name: Álvaro F. full_name: Fernández, Álvaro F. last_name: Fernández - first_name: Jose C. full_name: Fernandez-Checa, Jose C. last_name: Fernandez-Checa - first_name: Sonia full_name: Fernández-Veledo, Sonia last_name: Fernández-Veledo - first_name: Alisdair R. full_name: Fernie, Alisdair R. last_name: Fernie - first_name: Anthony W. full_name: Ferrante, Anthony W. last_name: Ferrante - first_name: Alessandra full_name: Ferraresi, Alessandra last_name: Ferraresi - first_name: Merari F. full_name: Ferrari, Merari F. last_name: Ferrari - first_name: Julio C.B. full_name: Ferreira, Julio C.B. last_name: Ferreira - first_name: Susan full_name: Ferro-Novick, Susan last_name: Ferro-Novick - first_name: Antonio full_name: Figueras, Antonio last_name: Figueras - first_name: Riccardo full_name: Filadi, Riccardo last_name: Filadi - first_name: Nicoletta full_name: Filigheddu, Nicoletta last_name: Filigheddu - first_name: Eduardo full_name: Filippi-Chiela, Eduardo last_name: Filippi-Chiela - first_name: Giuseppe full_name: Filomeni, Giuseppe last_name: Filomeni - first_name: Gian Maria full_name: Fimia, Gian Maria last_name: Fimia - first_name: Vittorio full_name: Fineschi, Vittorio last_name: Fineschi - first_name: Francesca full_name: Finetti, Francesca last_name: Finetti - first_name: Steven full_name: Finkbeiner, Steven last_name: Finkbeiner - first_name: Edward A. full_name: Fisher, Edward A. last_name: Fisher - first_name: Paul B. full_name: Fisher, Paul B. last_name: Fisher - first_name: Flavio full_name: Flamigni, Flavio last_name: Flamigni - first_name: Steven J. full_name: Fliesler, Steven J. last_name: Fliesler - first_name: Trude H. full_name: Flo, Trude H. last_name: Flo - first_name: Ida full_name: Florance, Ida last_name: Florance - first_name: Oliver full_name: Florey, Oliver last_name: Florey - first_name: Tullio full_name: Florio, Tullio last_name: Florio - first_name: Erika full_name: Fodor, Erika last_name: Fodor - first_name: Carlo full_name: Follo, Carlo last_name: Follo - first_name: Edward A. full_name: Fon, Edward A. last_name: Fon - first_name: Antonella full_name: Forlino, Antonella last_name: Forlino - first_name: Francesco full_name: Fornai, Francesco last_name: Fornai - first_name: Paola full_name: Fortini, Paola last_name: Fortini - first_name: Anna full_name: Fracassi, Anna last_name: Fracassi - first_name: Alessandro full_name: Fraldi, Alessandro last_name: Fraldi - first_name: Brunella full_name: Franco, Brunella last_name: Franco - first_name: Rodrigo full_name: Franco, Rodrigo last_name: Franco - first_name: Flavia full_name: Franconi, Flavia last_name: Franconi - first_name: Lisa B. full_name: Frankel, Lisa B. last_name: Frankel - 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first_name: Alessia full_name: Galasso, Alessia last_name: Galasso - first_name: Maria F. full_name: Galindo, Maria F. last_name: Galindo - first_name: Sachith full_name: Gallolu Kankanamalage, Sachith last_name: Gallolu Kankanamalage - first_name: Lorenzo full_name: Galluzzi, Lorenzo last_name: Galluzzi - first_name: Vincent full_name: Galy, Vincent last_name: Galy - first_name: Noor full_name: Gammoh, Noor last_name: Gammoh - first_name: Boyi full_name: Gan, Boyi last_name: Gan - first_name: Ian G. full_name: Ganley, Ian G. last_name: Ganley - first_name: Feng full_name: Gao, Feng last_name: Gao - first_name: Hui full_name: Gao, Hui last_name: Gao - first_name: Minghui full_name: Gao, Minghui last_name: Gao - first_name: Ping full_name: Gao, Ping last_name: Gao - first_name: Shou Jiang full_name: Gao, Shou Jiang last_name: Gao - first_name: Wentao full_name: Gao, Wentao last_name: Gao - first_name: Xiaobo full_name: Gao, Xiaobo last_name: Gao - first_name: Ana full_name: Garcera, Ana last_name: Garcera - first_name: Maria Noé full_name: Garcia, Maria Noé last_name: Garcia - first_name: Verónica E. full_name: Garcia, Verónica E. last_name: Garcia - first_name: Francisco full_name: García-Del Portillo, Francisco last_name: García-Del Portillo - first_name: Vega full_name: Garcia-Escudero, Vega last_name: Garcia-Escudero - first_name: Aracely full_name: Garcia-Garcia, Aracely last_name: Garcia-Garcia - first_name: Marina full_name: Garcia-Macia, Marina last_name: Garcia-Macia - first_name: Diana full_name: García-Moreno, Diana last_name: García-Moreno - first_name: Carmen full_name: Garcia-Ruiz, Carmen last_name: Garcia-Ruiz - first_name: Patricia full_name: García-Sanz, Patricia last_name: García-Sanz - first_name: Abhishek D. full_name: Garg, Abhishek D. last_name: Garg - first_name: Ricardo full_name: Gargini, Ricardo last_name: Gargini - first_name: Tina full_name: Garofalo, Tina last_name: Garofalo - first_name: Robert F. full_name: Garry, Robert F. last_name: Garry - first_name: Nils C. full_name: Gassen, Nils C. last_name: Gassen - 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first_name: Manosij full_name: Ghosh, Manosij last_name: Ghosh - first_name: Georgios full_name: Giamas, Georgios last_name: Giamas - first_name: Claudia full_name: Giampietri, Claudia last_name: Giampietri - first_name: Alexandra full_name: Giatromanolaki, Alexandra last_name: Giatromanolaki - first_name: Gary E. full_name: Gibson, Gary E. last_name: Gibson - first_name: Spencer B. full_name: Gibson, Spencer B. last_name: Gibson - first_name: Vanessa full_name: Ginet, Vanessa last_name: Ginet - first_name: Edward full_name: Giniger, Edward last_name: Giniger - first_name: Carlotta full_name: Giorgi, Carlotta last_name: Giorgi - first_name: Henrique full_name: Girao, Henrique last_name: Girao - first_name: Stephen E. full_name: Girardin, Stephen E. last_name: Girardin - first_name: Mridhula full_name: Giridharan, Mridhula last_name: Giridharan - first_name: Sandy full_name: Giuliano, Sandy last_name: Giuliano - first_name: Cecilia full_name: Giulivi, Cecilia last_name: Giulivi - first_name: Sylvie full_name: Giuriato, Sylvie last_name: Giuriato - first_name: Julien full_name: Giustiniani, Julien last_name: Giustiniani - first_name: Alexander full_name: Gluschko, Alexander last_name: Gluschko - first_name: Veit full_name: Goder, Veit last_name: Goder - first_name: Alexander full_name: Goginashvili, Alexander last_name: Goginashvili - first_name: Jakub full_name: Golab, Jakub last_name: Golab - first_name: David C. full_name: Goldstone, David C. last_name: Goldstone - first_name: Anna full_name: Golebiewska, Anna last_name: Golebiewska - first_name: Luciana R. full_name: Gomes, Luciana R. last_name: Gomes - first_name: Rodrigo full_name: Gomez, Rodrigo last_name: Gomez - first_name: Rubén full_name: Gómez-Sánchez, Rubén last_name: Gómez-Sánchez - first_name: Maria Catalina full_name: Gomez-Puerto, Maria Catalina last_name: Gomez-Puerto - first_name: Raquel full_name: Gomez-Sintes, Raquel last_name: Gomez-Sintes - first_name: Qingqiu full_name: Gong, Qingqiu last_name: Gong - first_name: Felix M. full_name: Goni, Felix M. last_name: Goni - 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first_name: Nirmala full_name: Hariharan, Nirmala last_name: Hariharan - first_name: Nigil full_name: Haroon, Nigil last_name: Haroon - first_name: James full_name: Harris, James last_name: Harris - first_name: Takafumi full_name: Hasegawa, Takafumi last_name: Hasegawa - first_name: Noor full_name: Hasima Nagoor, Noor last_name: Hasima Nagoor - first_name: Jeffrey A. full_name: Haspel, Jeffrey A. last_name: Haspel - first_name: Volker full_name: Haucke, Volker last_name: Haucke - first_name: Wayne D. full_name: Hawkins, Wayne D. last_name: Hawkins - first_name: Bruce A. full_name: Hay, Bruce A. last_name: Hay - first_name: Cole M. full_name: Haynes, Cole M. last_name: Haynes - first_name: Soren B. full_name: Hayrabedyan, Soren B. last_name: Hayrabedyan - first_name: Thomas S. full_name: Hays, Thomas S. last_name: Hays - first_name: Congcong full_name: He, Congcong last_name: He - first_name: Qin full_name: He, Qin last_name: He - first_name: Rong Rong full_name: He, Rong Rong last_name: He - 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first_name: José M. full_name: Izquierdo, José M. last_name: Izquierdo - first_name: Masanori full_name: Izumi, Masanori last_name: Izumi - first_name: Marja full_name: Jäättelä, Marja last_name: Jäättelä - first_name: Majid Sakhi full_name: Jabir, Majid Sakhi last_name: Jabir - first_name: William T. full_name: Jackson, William T. last_name: Jackson - first_name: Nadia full_name: Jacobo-Herrera, Nadia last_name: Jacobo-Herrera - first_name: Anne Claire full_name: Jacomin, Anne Claire last_name: Jacomin - first_name: Elise full_name: Jacquin, Elise last_name: Jacquin - first_name: Pooja full_name: Jadiya, Pooja last_name: Jadiya - first_name: Hartmut full_name: Jaeschke, Hartmut last_name: Jaeschke - first_name: Chinnaswamy full_name: Jagannath, Chinnaswamy last_name: Jagannath - first_name: Arjen J. full_name: Jakobi, Arjen J. last_name: Jakobi - first_name: Johan full_name: Jakobsson, Johan last_name: Jakobsson - first_name: Bassam full_name: Janji, Bassam last_name: Janji - first_name: Pidder full_name: Jansen-Dürr, Pidder last_name: Jansen-Dürr - 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first_name: Dimitri full_name: Krainc, Dimitri last_name: Krainc - first_name: Helmut full_name: Krämer, Helmut last_name: Krämer - first_name: Anna D. full_name: Krasnodembskaya, Anna D. last_name: Krasnodembskaya - first_name: Carole full_name: Kretz-Remy, Carole last_name: Kretz-Remy - first_name: Guido full_name: Kroemer, Guido last_name: Kroemer - first_name: Nicholas T. full_name: Ktistakis, Nicholas T. last_name: Ktistakis - first_name: Kazuyuki full_name: Kuchitsu, Kazuyuki last_name: Kuchitsu - first_name: Sabine full_name: Kuenen, Sabine last_name: Kuenen - first_name: Lars full_name: Kuerschner, Lars last_name: Kuerschner - first_name: Thomas full_name: Kukar, Thomas last_name: Kukar - first_name: Ajay full_name: Kumar, Ajay last_name: Kumar - first_name: Ashok full_name: Kumar, Ashok last_name: Kumar - first_name: Deepak full_name: Kumar, Deepak last_name: Kumar - first_name: Dhiraj full_name: Kumar, Dhiraj last_name: Kumar - first_name: Sharad full_name: Kumar, Sharad last_name: Kumar - 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first_name: Sylvain full_name: Ladoire, Sylvain last_name: Ladoire - first_name: Ilaria full_name: Laface, Ilaria last_name: Laface - first_name: Frank full_name: Lafont, Frank last_name: Lafont - first_name: Diane C. full_name: Lagace, Diane C. last_name: Lagace - first_name: Vikramjit full_name: Lahiri, Vikramjit last_name: Lahiri - first_name: Zhibing full_name: Lai, Zhibing last_name: Lai - first_name: Angela S. full_name: Laird, Angela S. last_name: Laird - first_name: Aparna full_name: Lakkaraju, Aparna last_name: Lakkaraju - first_name: Trond full_name: Lamark, Trond last_name: Lamark - first_name: Sheng Hui full_name: Lan, Sheng Hui last_name: Lan - first_name: Ane full_name: Landajuela, Ane last_name: Landajuela - first_name: Darius J.R. full_name: Lane, Darius J.R. last_name: Lane - first_name: Jon D. full_name: Lane, Jon D. last_name: Lane - first_name: Charles H. full_name: Lang, Charles H. last_name: Lang - first_name: Carsten full_name: Lange, Carsten last_name: Lange - first_name: Ülo full_name: Langel, Ülo last_name: Langel - 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first_name: Lionel Y.W. full_name: Leck, Lionel Y.W. last_name: Leck - first_name: Jean Philippe full_name: Leduc-Gaudet, Jean Philippe last_name: Leduc-Gaudet - first_name: Changwook full_name: Lee, Changwook last_name: Lee - first_name: Chung Pei full_name: Lee, Chung Pei last_name: Lee - first_name: Da Hye full_name: Lee, Da Hye last_name: Lee - first_name: Edward B. full_name: Lee, Edward B. last_name: Lee - first_name: Erinna F. full_name: Lee, Erinna F. last_name: Lee - first_name: Gyun Min full_name: Lee, Gyun Min last_name: Lee - first_name: He Jin full_name: Lee, He Jin last_name: Lee - first_name: Heung Kyu full_name: Lee, Heung Kyu last_name: Lee - first_name: Jae Man full_name: Lee, Jae Man last_name: Lee - first_name: Jason S. full_name: Lee, Jason S. last_name: Lee - first_name: Jin A. full_name: Lee, Jin A. last_name: Lee - first_name: Joo Yong full_name: Lee, Joo Yong last_name: Lee - first_name: Jun Hee full_name: Lee, Jun Hee last_name: Lee - first_name: Michael full_name: Lee, Michael last_name: Lee - 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first_name: Honglin full_name: Luo, Honglin last_name: Luo - first_name: Rongcan full_name: Luo, Rongcan last_name: Luo - first_name: Shouqing full_name: Luo, Shouqing last_name: Luo - first_name: Zhi full_name: Luo, Zhi last_name: Luo - first_name: Claudio full_name: Luparello, Claudio last_name: Luparello - first_name: Bernhard full_name: Lüscher, Bernhard last_name: Lüscher - first_name: Luan full_name: Luu, Luan last_name: Luu - first_name: Alex full_name: Lyakhovich, Alex last_name: Lyakhovich - first_name: Konstantin G. full_name: Lyamzaev, Konstantin G. last_name: Lyamzaev - first_name: Alf Håkon full_name: Lystad, Alf Håkon last_name: Lystad - first_name: Lyubomyr full_name: Lytvynchuk, Lyubomyr last_name: Lytvynchuk - first_name: Alvin C. full_name: Ma, Alvin C. last_name: Ma - first_name: Changle full_name: Ma, Changle last_name: Ma - first_name: Mengxiao full_name: Ma, Mengxiao last_name: Ma - first_name: Ning Fang full_name: Ma, Ning Fang last_name: Ma - first_name: Quan Hong full_name: Ma, Quan Hong last_name: Ma - first_name: Xinliang full_name: Ma, Xinliang last_name: Ma - first_name: Yueyun full_name: Ma, Yueyun last_name: Ma - first_name: Zhenyi full_name: Ma, Zhenyi last_name: Ma - first_name: Ormond A. full_name: Macdougald, Ormond A. last_name: Macdougald - first_name: Fernando full_name: Macian, Fernando last_name: Macian - first_name: Gustavo C. full_name: Macintosh, Gustavo C. last_name: Macintosh - first_name: Jeffrey P. full_name: Mackeigan, Jeffrey P. last_name: Mackeigan - first_name: Kay F. full_name: Macleod, Kay F. last_name: Macleod - first_name: Sandra full_name: Maday, Sandra last_name: Maday - first_name: Frank full_name: Madeo, Frank last_name: Madeo - first_name: Muniswamy full_name: Madesh, Muniswamy last_name: Madesh - first_name: Tobias full_name: Madl, Tobias last_name: Madl - first_name: Julio full_name: Madrigal-Matute, Julio last_name: Madrigal-Matute - first_name: Akiko full_name: Maeda, Akiko last_name: Maeda - first_name: Yasuhiro full_name: Maejima, Yasuhiro last_name: Maejima - first_name: Marta full_name: Magarinos, Marta last_name: Magarinos - first_name: Poornima full_name: Mahavadi, Poornima last_name: Mahavadi - first_name: Emiliano full_name: Maiani, Emiliano last_name: Maiani - first_name: Kenneth full_name: Maiese, Kenneth last_name: Maiese - first_name: Panchanan full_name: Maiti, Panchanan last_name: Maiti - first_name: Maria Chiara full_name: Maiuri, Maria Chiara last_name: Maiuri - first_name: Barbara full_name: Majello, Barbara last_name: Majello - first_name: Michael B. full_name: Major, Michael B. last_name: Major - first_name: Elena full_name: Makareeva, Elena last_name: Makareeva - first_name: Fayaz full_name: Malik, Fayaz last_name: Malik - first_name: Karthik full_name: Mallilankaraman, Karthik last_name: Mallilankaraman - first_name: Walter full_name: Malorni, Walter last_name: Malorni - first_name: Alina full_name: Maloyan, Alina last_name: Maloyan - first_name: Najiba full_name: Mammadova, Najiba last_name: Mammadova - first_name: Gene Chi Wai full_name: Man, Gene Chi Wai last_name: Man - first_name: Federico full_name: Manai, Federico last_name: Manai - first_name: Joseph D. full_name: Mancias, Joseph D. last_name: Mancias - first_name: Eva Maria full_name: Mandelkow, Eva Maria last_name: Mandelkow - first_name: Michael A. full_name: Mandell, Michael A. last_name: Mandell - first_name: Angelo A. full_name: Manfredi, Angelo A. last_name: Manfredi - first_name: Masoud H. full_name: Manjili, Masoud H. last_name: Manjili - first_name: Ravi full_name: Manjithaya, Ravi last_name: Manjithaya - first_name: Patricio full_name: Manque, Patricio last_name: Manque - first_name: Bella B. full_name: Manshian, Bella B. last_name: Manshian - first_name: Raquel full_name: Manzano, Raquel last_name: Manzano - first_name: Claudia full_name: Manzoni, Claudia last_name: Manzoni - first_name: Kai full_name: Mao, Kai last_name: Mao - first_name: Cinzia full_name: Marchese, Cinzia last_name: Marchese - first_name: Sandrine full_name: Marchetti, Sandrine last_name: Marchetti - first_name: Anna Maria full_name: Marconi, Anna Maria last_name: Marconi - first_name: Fabrizio full_name: Marcucci, Fabrizio last_name: Marcucci - first_name: Stefania full_name: Mardente, Stefania last_name: Mardente - first_name: Olga A. full_name: Mareninova, Olga A. last_name: Mareninova - first_name: Marta full_name: Margeta, Marta last_name: Margeta - first_name: Muriel full_name: Mari, Muriel last_name: Mari - first_name: Sara full_name: Marinelli, Sara last_name: Marinelli - first_name: Oliviero full_name: Marinelli, Oliviero last_name: Marinelli - first_name: Guillermo full_name: Mariño, Guillermo last_name: Mariño - first_name: Sofia full_name: Mariotto, Sofia last_name: Mariotto - first_name: Richard S. full_name: Marshall, Richard S. last_name: Marshall - first_name: Mark R. full_name: Marten, Mark R. last_name: Marten - first_name: Sascha full_name: Martens, Sascha last_name: Martens - first_name: Alexandre P.J. full_name: Martin, Alexandre P.J. last_name: Martin - first_name: Katie R. full_name: Martin, Katie R. last_name: Martin - first_name: Sara full_name: Martin, Sara last_name: Martin - first_name: Shaun full_name: Martin, Shaun last_name: Martin - first_name: Adrián full_name: Martín-Segura, Adrián last_name: Martín-Segura - first_name: Miguel A. full_name: Martín-Acebes, Miguel A. last_name: Martín-Acebes - first_name: Inmaculada full_name: Martin-Burriel, Inmaculada last_name: Martin-Burriel - first_name: Marcos full_name: Martin-Rincon, Marcos last_name: Martin-Rincon - first_name: Paloma full_name: Martin-Sanz, Paloma last_name: Martin-Sanz - first_name: José A. full_name: Martina, José A. last_name: Martina - first_name: Wim full_name: Martinet, Wim last_name: Martinet - first_name: Aitor full_name: Martinez, Aitor last_name: Martinez - first_name: Ana full_name: Martinez, Ana last_name: Martinez - first_name: Jennifer full_name: Martinez, Jennifer last_name: Martinez - first_name: Moises full_name: Martinez Velazquez, Moises last_name: Martinez Velazquez - first_name: Nuria full_name: Martinez-Lopez, Nuria last_name: Martinez-Lopez - first_name: Marta full_name: Martinez-Vicente, Marta last_name: Martinez-Vicente - first_name: Daniel O. full_name: Martins, Daniel O. last_name: Martins - first_name: Joilson O. full_name: Martins, Joilson O. last_name: Martins - first_name: Waleska K. full_name: Martins, Waleska K. last_name: Martins - first_name: Tania full_name: Martins-Marques, Tania last_name: Martins-Marques - first_name: Emanuele full_name: Marzetti, Emanuele last_name: Marzetti - first_name: Shashank full_name: Masaldan, Shashank last_name: Masaldan - first_name: Celine full_name: Masclaux-Daubresse, Celine last_name: Masclaux-Daubresse - first_name: Douglas G. full_name: Mashek, Douglas G. last_name: Mashek - first_name: Valentina full_name: Massa, Valentina last_name: Massa - first_name: Lourdes full_name: Massieu, Lourdes last_name: Massieu - first_name: Glenn R. full_name: Masson, Glenn R. last_name: Masson - first_name: Laura full_name: Masuelli, Laura last_name: Masuelli - first_name: Anatoliy I. full_name: Masyuk, Anatoliy I. last_name: Masyuk - first_name: Tetyana V. full_name: Masyuk, Tetyana V. last_name: Masyuk - first_name: Paola full_name: Matarrese, Paola last_name: Matarrese - first_name: Ander full_name: Matheu, Ander last_name: Matheu - first_name: Satoaki full_name: Matoba, Satoaki last_name: Matoba - first_name: Sachiko full_name: Matsuzaki, Sachiko last_name: Matsuzaki - first_name: Pamela full_name: Mattar, Pamela last_name: Mattar - first_name: Alessandro full_name: Matte, Alessandro last_name: Matte - first_name: Domenico full_name: Mattoscio, Domenico last_name: Mattoscio - first_name: José L. full_name: Mauriz, José L. last_name: Mauriz - first_name: Mario full_name: Mauthe, Mario last_name: Mauthe - first_name: Caroline full_name: Mauvezin, Caroline last_name: Mauvezin - first_name: Emanual full_name: Maverakis, Emanual last_name: Maverakis - first_name: Paola full_name: Maycotte, Paola last_name: Maycotte - first_name: Johanna full_name: Mayer, Johanna last_name: Mayer - first_name: Gianluigi full_name: Mazzoccoli, Gianluigi last_name: Mazzoccoli - first_name: Cristina full_name: Mazzoni, Cristina last_name: Mazzoni - first_name: Joseph R. full_name: Mazzulli, Joseph R. last_name: Mazzulli - first_name: Nami full_name: Mccarty, Nami last_name: Mccarty - first_name: Christine full_name: Mcdonald, Christine last_name: Mcdonald - first_name: Mitchell R. full_name: Mcgill, Mitchell R. last_name: Mcgill - first_name: Sharon L. full_name: Mckenna, Sharon L. last_name: Mckenna - first_name: Beth Ann full_name: Mclaughlin, Beth Ann last_name: Mclaughlin - first_name: Fionn full_name: Mcloughlin, Fionn last_name: Mcloughlin - first_name: Mark A. full_name: Mcniven, Mark A. last_name: Mcniven - first_name: Thomas G. full_name: Mcwilliams, Thomas G. last_name: Mcwilliams - first_name: Fatima full_name: Mechta-Grigoriou, Fatima last_name: Mechta-Grigoriou - first_name: Tania Catarina full_name: Medeiros, Tania Catarina last_name: Medeiros - first_name: Diego L. full_name: Medina, Diego L. last_name: Medina - first_name: Lynn A. full_name: Megeney, Lynn A. last_name: Megeney - first_name: Klara full_name: Megyeri, Klara last_name: Megyeri - 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first_name: Enrico full_name: Milan, Enrico last_name: Milan - first_name: Małgorzata full_name: Milczarek, Małgorzata last_name: Milczarek - first_name: Dana L. full_name: Miller, Dana L. last_name: Miller - first_name: Samuel I. full_name: Miller, Samuel I. last_name: Miller - first_name: Silke full_name: Miller, Silke last_name: Miller - first_name: Steven W. full_name: Millward, Steven W. last_name: Millward - first_name: Ira full_name: Milosevic, Ira last_name: Milosevic - first_name: Elena A. full_name: Minina, Elena A. last_name: Minina - first_name: Hamed full_name: Mirzaei, Hamed last_name: Mirzaei - first_name: Hamid Reza full_name: Mirzaei, Hamid Reza last_name: Mirzaei - first_name: Mehdi full_name: Mirzaei, Mehdi last_name: Mirzaei - first_name: Amit full_name: Mishra, Amit last_name: Mishra - first_name: Nandita full_name: Mishra, Nandita last_name: Mishra - first_name: Paras Kumar full_name: Mishra, Paras Kumar last_name: Mishra - first_name: Maja full_name: Misirkic Marjanovic, Maja last_name: Misirkic Marjanovic - first_name: Roberta full_name: Misasi, Roberta last_name: Misasi - first_name: Amit full_name: Misra, Amit last_name: Misra - first_name: Gabriella full_name: Misso, Gabriella last_name: Misso - first_name: Claire full_name: Mitchell, Claire last_name: Mitchell - first_name: Geraldine full_name: Mitou, Geraldine last_name: Mitou - first_name: Tetsuji full_name: Miura, Tetsuji last_name: Miura - first_name: Shigeki full_name: Miyamoto, Shigeki last_name: Miyamoto - first_name: Makoto full_name: Miyazaki, Makoto last_name: Miyazaki - first_name: Mitsunori full_name: Miyazaki, Mitsunori last_name: Miyazaki - first_name: Taiga full_name: Miyazaki, Taiga last_name: Miyazaki - first_name: Keisuke full_name: Miyazawa, Keisuke last_name: Miyazawa - first_name: Noboru full_name: Mizushima, Noboru last_name: Mizushima - first_name: Trine H. full_name: Mogensen, Trine H. last_name: Mogensen - first_name: Baharia full_name: Mograbi, Baharia last_name: Mograbi - first_name: Reza full_name: Mohammadinejad, Reza last_name: Mohammadinejad - 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Patrick full_name: Murphy, J. 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Celeste full_name: Nicolao, M. 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Bishr full_name: Omary, M. 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first_name: Kinya full_name: Otsu, Kinya last_name: Otsu - first_name: Christiane full_name: Ott, Christiane last_name: Ott - first_name: Luisa full_name: Ottobrini, Luisa last_name: Ottobrini - first_name: Jing Hsiung James full_name: Ou, Jing Hsiung James last_name: Ou - first_name: Tiago F. full_name: Outeiro, Tiago F. last_name: Outeiro - first_name: Inger full_name: Oynebraten, Inger last_name: Oynebraten - first_name: Melek full_name: Ozturk, Melek last_name: Ozturk - first_name: Gilles full_name: Pagès, Gilles last_name: Pagès - first_name: Susanta full_name: Pahari, Susanta last_name: Pahari - first_name: Marta full_name: Pajares, Marta last_name: Pajares - first_name: Utpal B. full_name: Pajvani, Utpal B. last_name: Pajvani - first_name: Rituraj full_name: Pal, Rituraj last_name: Pal - first_name: Simona full_name: Paladino, Simona last_name: Paladino - first_name: Nicolas full_name: Pallet, Nicolas last_name: Pallet - first_name: Michela full_name: Palmieri, Michela last_name: Palmieri - first_name: Giuseppe full_name: Palmisano, Giuseppe last_name: Palmisano - first_name: Camilla full_name: Palumbo, Camilla last_name: Palumbo - first_name: Francesco full_name: Pampaloni, Francesco last_name: Pampaloni - first_name: Lifeng full_name: Pan, Lifeng last_name: Pan - first_name: Qingjun full_name: Pan, Qingjun last_name: Pan - first_name: Wenliang full_name: Pan, Wenliang last_name: Pan - first_name: Xin full_name: Pan, Xin last_name: Pan - first_name: Ganna full_name: Panasyuk, Ganna last_name: Panasyuk - first_name: Rahul full_name: Pandey, Rahul last_name: Pandey - first_name: Udai B. full_name: Pandey, Udai B. last_name: Pandey - first_name: Vrajesh full_name: Pandya, Vrajesh last_name: Pandya - first_name: Francesco full_name: Paneni, Francesco last_name: Paneni - first_name: Shirley Y. full_name: Pang, Shirley Y. last_name: Pang - first_name: Elisa full_name: Panzarini, Elisa last_name: Panzarini - first_name: Daniela L. full_name: Papademetrio, Daniela L. last_name: Papademetrio - first_name: Elena full_name: Papaleo, Elena last_name: Papaleo - first_name: Daniel full_name: Papinski, Daniel last_name: Papinski - first_name: Diana full_name: Papp, Diana last_name: Papp - first_name: Eun Chan full_name: Park, Eun Chan last_name: Park - first_name: Hwan Tae full_name: Park, Hwan Tae last_name: Park - first_name: Ji Man full_name: Park, Ji Man last_name: Park - first_name: Jong In full_name: Park, Jong In last_name: Park - first_name: Joon Tae full_name: Park, Joon Tae last_name: Park - first_name: Junsoo full_name: Park, Junsoo last_name: Park - first_name: Sang Chul full_name: Park, Sang Chul last_name: Park - first_name: Sang Youel full_name: Park, Sang Youel last_name: Park - first_name: Abraham H. full_name: Parola, Abraham H. last_name: Parola - first_name: Jan B. full_name: Parys, Jan B. last_name: Parys - first_name: Adrien full_name: Pasquier, Adrien last_name: Pasquier - first_name: Benoit full_name: Pasquier, Benoit last_name: Pasquier - first_name: João F. full_name: Passos, João F. last_name: Passos - first_name: Nunzia full_name: Pastore, Nunzia last_name: Pastore - first_name: Hemal H. full_name: Patel, Hemal H. last_name: Patel - first_name: Daniel full_name: Patschan, Daniel last_name: Patschan - first_name: Sophie full_name: Pattingre, Sophie last_name: Pattingre - first_name: Gustavo full_name: Pedraza-Alva, Gustavo last_name: Pedraza-Alva - first_name: Jose full_name: Pedraza-Chaverri, Jose last_name: Pedraza-Chaverri - first_name: Zully full_name: Pedrozo, Zully last_name: Pedrozo - first_name: Gang full_name: Pei, Gang last_name: Pei - first_name: Jianming full_name: Pei, Jianming last_name: Pei - first_name: Hadas full_name: Peled-Zehavi, Hadas last_name: Peled-Zehavi - first_name: Joaquín M. full_name: Pellegrini, Joaquín M. last_name: Pellegrini - first_name: Joffrey full_name: Pelletier, Joffrey last_name: Pelletier - first_name: Miguel A. full_name: Peñalva, Miguel A. last_name: Peñalva - first_name: Di full_name: Peng, Di last_name: Peng - first_name: Ying full_name: Peng, Ying last_name: Peng - first_name: Fabio full_name: Penna, Fabio last_name: Penna - first_name: Maria full_name: Pennuto, Maria last_name: Pennuto - first_name: Francesca full_name: Pentimalli, Francesca last_name: Pentimalli - first_name: Cláudia M.F. full_name: Pereira, Cláudia M.F. last_name: Pereira - first_name: Gustavo J.S. full_name: Pereira, Gustavo J.S. last_name: Pereira - first_name: Lilian C. full_name: Pereira, Lilian C. last_name: Pereira - first_name: Luis full_name: Pereira De Almeida, Luis last_name: Pereira De Almeida - first_name: Nirma D. full_name: Perera, Nirma D. last_name: Perera - first_name: Ángel full_name: Pérez-Lara, Ángel last_name: Pérez-Lara - first_name: Ana B. full_name: Perez-Oliva, Ana B. last_name: Perez-Oliva - first_name: María Esther full_name: Pérez-Pérez, María Esther last_name: Pérez-Pérez - first_name: Palsamy full_name: Periyasamy, Palsamy last_name: Periyasamy - first_name: Andras full_name: Perl, Andras last_name: Perl - first_name: Cristiana full_name: Perrotta, Cristiana last_name: Perrotta - 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first_name: Michael J. full_name: Ragusa, Michael J. last_name: Ragusa - first_name: Nader full_name: Rahimi, Nader last_name: Rahimi - first_name: Marveh full_name: Rahmati, Marveh last_name: Rahmati - first_name: Valeria full_name: Raia, Valeria last_name: Raia - first_name: Nuno full_name: Raimundo, Nuno last_name: Raimundo - first_name: Namakkal Soorappan full_name: Rajasekaran, Namakkal Soorappan last_name: Rajasekaran - first_name: Sriganesh full_name: Ramachandra Rao, Sriganesh last_name: Ramachandra Rao - first_name: Abdelhaq full_name: Rami, Abdelhaq last_name: Rami - first_name: Ignacio full_name: Ramírez-Pardo, Ignacio last_name: Ramírez-Pardo - first_name: David B. full_name: Ramsden, David B. last_name: Ramsden - first_name: Felix full_name: Randow, Felix last_name: Randow - first_name: Pundi N. full_name: Rangarajan, Pundi N. last_name: Rangarajan - first_name: Danilo full_name: Ranieri, Danilo last_name: Ranieri - first_name: Hai full_name: Rao, Hai last_name: Rao - first_name: Lang full_name: Rao, Lang last_name: Rao - first_name: Rekha full_name: Rao, Rekha last_name: Rao - first_name: Sumit full_name: Rathore, Sumit last_name: Rathore - first_name: J. Arjuna full_name: Ratnayaka, J. Arjuna last_name: Ratnayaka - first_name: Edward A. full_name: Ratovitski, Edward A. last_name: Ratovitski - first_name: Palaniyandi full_name: Ravanan, Palaniyandi last_name: Ravanan - first_name: Gloria full_name: Ravegnini, Gloria last_name: Ravegnini - first_name: Swapan K. full_name: Ray, Swapan K. last_name: Ray - first_name: Babak full_name: Razani, Babak last_name: Razani - first_name: Vito full_name: Rebecca, Vito last_name: Rebecca - first_name: Fulvio full_name: Reggiori, Fulvio last_name: Reggiori - first_name: Anne full_name: Régnier-Vigouroux, Anne last_name: Régnier-Vigouroux - first_name: Andreas S. full_name: Reichert, Andreas S. last_name: Reichert - first_name: David full_name: Reigada, David last_name: Reigada - first_name: Jan H. full_name: Reiling, Jan H. last_name: Reiling - first_name: Theo full_name: Rein, Theo last_name: Rein - first_name: Siegfried full_name: Reipert, Siegfried last_name: Reipert - first_name: Rokeya Sultana full_name: Rekha, Rokeya Sultana last_name: Rekha - first_name: Hongmei full_name: Ren, Hongmei last_name: Ren - first_name: Jun full_name: Ren, Jun last_name: Ren - first_name: Weichao full_name: Ren, Weichao last_name: Ren - first_name: Tristan full_name: Renault, Tristan last_name: Renault - first_name: Giorgia full_name: Renga, Giorgia last_name: Renga - first_name: Karen full_name: Reue, Karen last_name: Reue - first_name: Kim full_name: Rewitz, Kim last_name: Rewitz - first_name: Bruna full_name: Ribeiro De Andrade Ramos, Bruna last_name: Ribeiro De Andrade Ramos - first_name: S. Amer full_name: Riazuddin, S. Amer last_name: Riazuddin - first_name: Teresa M. full_name: Ribeiro-Rodrigues, Teresa M. last_name: Ribeiro-Rodrigues - first_name: Jean Ehrland full_name: Ricci, Jean Ehrland last_name: Ricci - first_name: Romeo full_name: Ricci, Romeo last_name: Ricci - first_name: Victoria full_name: Riccio, Victoria last_name: Riccio - first_name: Des R. full_name: Richardson, Des R. last_name: Richardson - first_name: Yasuko full_name: Rikihisa, Yasuko last_name: Rikihisa - first_name: Makarand V. full_name: Risbud, Makarand V. last_name: Risbud - first_name: Ruth M. full_name: Risueño, Ruth M. last_name: Risueño - first_name: Konstantinos full_name: Ritis, Konstantinos last_name: Ritis - first_name: Salvatore full_name: Rizza, Salvatore last_name: Rizza - first_name: Rosario full_name: Rizzuto, Rosario last_name: Rizzuto - first_name: Helen C. full_name: Roberts, Helen C. last_name: Roberts - first_name: Luke D. full_name: Roberts, Luke D. last_name: Roberts - first_name: Katherine J. full_name: Robinson, Katherine J. last_name: Robinson - first_name: Maria Carmela full_name: Roccheri, Maria Carmela last_name: Roccheri - first_name: Stephane full_name: Rocchi, Stephane last_name: Rocchi - first_name: George G. full_name: Rodney, George G. last_name: Rodney - first_name: Tiago full_name: Rodrigues, Tiago last_name: Rodrigues - first_name: Vagner Ramon full_name: Rodrigues Silva, Vagner Ramon last_name: Rodrigues Silva - first_name: Amaia full_name: Rodriguez, Amaia last_name: Rodriguez - first_name: Ruth full_name: Rodriguez-Barrueco, Ruth last_name: Rodriguez-Barrueco - first_name: Nieves full_name: Rodriguez-Henche, Nieves last_name: Rodriguez-Henche - first_name: Humberto full_name: Rodriguez-Rocha, Humberto last_name: Rodriguez-Rocha - first_name: Jeroen full_name: Roelofs, Jeroen last_name: Roelofs - first_name: Robert S. full_name: Rogers, Robert S. last_name: Rogers - first_name: Vladimir V. full_name: Rogov, Vladimir V. last_name: Rogov - first_name: Ana I. full_name: Rojo, Ana I. last_name: Rojo - first_name: Krzysztof full_name: Rolka, Krzysztof last_name: Rolka - first_name: Vanina full_name: Romanello, Vanina last_name: Romanello - first_name: Luigina full_name: Romani, Luigina last_name: Romani - first_name: Alessandra full_name: Romano, Alessandra last_name: Romano - first_name: Patricia S. full_name: Romano, Patricia S. last_name: Romano - first_name: David full_name: Romeo-Guitart, David last_name: Romeo-Guitart - first_name: Luis C. full_name: Romero, Luis C. last_name: Romero - first_name: Montserrat full_name: Romero, Montserrat last_name: Romero - first_name: Joseph C. full_name: Roney, Joseph C. last_name: Roney - first_name: Christopher full_name: Rongo, Christopher last_name: Rongo - first_name: Sante full_name: Roperto, Sante last_name: Roperto - first_name: Mathias T. full_name: Rosenfeldt, Mathias T. last_name: Rosenfeldt - first_name: Philip full_name: Rosenstiel, Philip last_name: Rosenstiel - first_name: Anne G. full_name: Rosenwald, Anne G. last_name: Rosenwald - first_name: Kevin A. full_name: Roth, Kevin A. last_name: Roth - first_name: Lynn full_name: Roth, Lynn last_name: Roth - first_name: Steven full_name: Roth, Steven last_name: Roth - first_name: Kasper M.A. full_name: Rouschop, Kasper M.A. last_name: Rouschop - first_name: Benoit D. full_name: Roussel, Benoit D. last_name: Roussel - first_name: Sophie full_name: Roux, Sophie last_name: Roux - first_name: Patrizia full_name: Rovere-Querini, Patrizia last_name: Rovere-Querini - first_name: Ajit full_name: Roy, Ajit last_name: Roy - first_name: Aurore full_name: Rozieres, Aurore last_name: Rozieres - first_name: Diego full_name: Ruano, Diego last_name: Ruano - first_name: David C. full_name: Rubinsztein, David C. last_name: Rubinsztein - first_name: Maria P. full_name: Rubtsova, Maria P. last_name: Rubtsova - first_name: Klaus full_name: Ruckdeschel, Klaus last_name: Ruckdeschel - first_name: Christoph full_name: Ruckenstuhl, Christoph last_name: Ruckenstuhl - first_name: Emil full_name: Rudolf, Emil last_name: Rudolf - first_name: Rüdiger full_name: Rudolf, Rüdiger last_name: Rudolf - first_name: Alessandra full_name: Ruggieri, Alessandra last_name: Ruggieri - first_name: Avnika Ashok full_name: Ruparelia, Avnika Ashok last_name: Ruparelia - first_name: Paola full_name: Rusmini, Paola last_name: Rusmini - first_name: Ryan R. full_name: Russell, Ryan R. last_name: Russell - first_name: Gian Luigi full_name: Russo, Gian Luigi last_name: Russo - first_name: Maria full_name: Russo, Maria last_name: Russo - first_name: Rossella full_name: Russo, Rossella last_name: Russo - first_name: Oxana O. full_name: Ryabaya, Oxana O. last_name: Ryabaya - first_name: Kevin M. full_name: Ryan, Kevin M. last_name: Ryan - first_name: Kwon Yul full_name: Ryu, Kwon Yul last_name: Ryu - first_name: Maria full_name: Sabater-Arcis, Maria last_name: Sabater-Arcis - first_name: Ulka full_name: Sachdev, Ulka last_name: Sachdev - first_name: Michael full_name: Sacher, Michael last_name: Sacher - first_name: Carsten full_name: Sachse, Carsten last_name: Sachse - first_name: Abhishek full_name: Sadhu, Abhishek last_name: Sadhu - first_name: Junichi full_name: Sadoshima, Junichi last_name: Sadoshima - first_name: Nathaniel full_name: Safren, Nathaniel last_name: Safren - first_name: Paul full_name: Saftig, Paul last_name: Saftig - first_name: Antonia P. full_name: Sagona, Antonia P. last_name: Sagona - first_name: Gaurav full_name: Sahay, Gaurav last_name: Sahay - first_name: Amirhossein full_name: Sahebkar, Amirhossein last_name: Sahebkar - first_name: Mustafa full_name: Sahin, Mustafa last_name: Sahin - first_name: Ozgur full_name: Sahin, Ozgur last_name: Sahin - first_name: Sumit full_name: Sahni, Sumit last_name: Sahni - first_name: Nayuta full_name: Saito, Nayuta last_name: Saito - first_name: Shigeru full_name: Saito, Shigeru last_name: Saito - first_name: Tsunenori full_name: Saito, Tsunenori last_name: Saito - first_name: Ryohei full_name: Sakai, Ryohei last_name: Sakai - first_name: Yasuyoshi full_name: Sakai, Yasuyoshi last_name: Sakai - first_name: Jun Ichi full_name: Sakamaki, Jun Ichi last_name: Sakamaki - first_name: Kalle full_name: Saksela, Kalle last_name: Saksela - first_name: Gloria full_name: Salazar, Gloria last_name: Salazar - first_name: Anna full_name: Salazar-Degracia, Anna last_name: Salazar-Degracia - first_name: Ghasem H. full_name: Salekdeh, Ghasem H. last_name: Salekdeh - first_name: Ashok K. full_name: Saluja, Ashok K. last_name: Saluja - first_name: Belém full_name: Sampaio-Marques, Belém last_name: Sampaio-Marques - first_name: Maria Cecilia full_name: Sanchez, Maria Cecilia last_name: Sanchez - first_name: Jose A. full_name: Sanchez-Alcazar, Jose A. last_name: Sanchez-Alcazar - first_name: Victoria full_name: Sanchez-Vera, Victoria last_name: Sanchez-Vera - first_name: Vanessa full_name: Sancho-Shimizu, Vanessa last_name: Sancho-Shimizu - first_name: J. Thomas full_name: Sanderson, J. Thomas last_name: Sanderson - first_name: Marco full_name: Sandri, Marco last_name: Sandri - first_name: Stefano full_name: Santaguida, Stefano last_name: Santaguida - first_name: Laura full_name: Santambrogio, Laura last_name: Santambrogio - first_name: Magda M. full_name: Santana, Magda M. last_name: Santana - first_name: Giorgio full_name: Santoni, Giorgio last_name: Santoni - first_name: Alberto full_name: Sanz, Alberto last_name: Sanz - first_name: Pascual full_name: Sanz, Pascual last_name: Sanz - first_name: Shweta full_name: Saran, Shweta last_name: Saran - first_name: Marco full_name: Sardiello, Marco last_name: Sardiello - first_name: Timothy J. full_name: Sargeant, Timothy J. last_name: Sargeant - first_name: Apurva full_name: Sarin, Apurva last_name: Sarin - first_name: Chinmoy full_name: Sarkar, Chinmoy last_name: Sarkar - first_name: Sovan full_name: Sarkar, Sovan last_name: Sarkar - first_name: Maria Rosa full_name: Sarrias, Maria Rosa last_name: Sarrias - first_name: Surajit full_name: Sarkar, Surajit last_name: Sarkar - first_name: Dipanka Tanu full_name: Sarmah, Dipanka Tanu last_name: Sarmah - first_name: Jaakko full_name: Sarparanta, Jaakko last_name: Sarparanta - first_name: Aishwarya full_name: Sathyanarayan, Aishwarya last_name: Sathyanarayan - first_name: Ranganayaki full_name: Sathyanarayanan, Ranganayaki last_name: Sathyanarayanan - first_name: K. Matthew full_name: Scaglione, K. 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Ivana full_name: Scovassi, A. 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first_name: Elena full_name: Seranova, Elena last_name: Seranova - first_name: Consolato full_name: Sergi, Consolato last_name: Sergi - first_name: Ruth full_name: Serra-Moreno, Ruth last_name: Serra-Moreno - first_name: Hiromi full_name: Sesaki, Hiromi last_name: Sesaki - first_name: Carmine full_name: Settembre, Carmine last_name: Settembre - first_name: Subba Rao Gangi full_name: Setty, Subba Rao Gangi last_name: Setty - first_name: Gianluca full_name: Sgarbi, Gianluca last_name: Sgarbi - first_name: Ou full_name: Sha, Ou last_name: Sha - first_name: John J. full_name: Shacka, John J. last_name: Shacka - first_name: Javeed A. full_name: Shah, Javeed A. last_name: Shah - first_name: Dantong full_name: Shang, Dantong last_name: Shang - first_name: Changshun full_name: Shao, Changshun last_name: Shao - first_name: Feng full_name: Shao, Feng last_name: Shao - first_name: Soroush full_name: Sharbati, Soroush last_name: Sharbati - first_name: Lisa M. full_name: Sharkey, Lisa M. last_name: Sharkey - first_name: Dipali full_name: Sharma, Dipali last_name: Sharma - first_name: Gaurav full_name: Sharma, Gaurav last_name: Sharma - first_name: Kulbhushan full_name: Sharma, Kulbhushan last_name: Sharma - first_name: Pawan full_name: Sharma, Pawan last_name: Sharma - first_name: Surendra full_name: Sharma, Surendra last_name: Sharma - first_name: Han Ming full_name: Shen, Han Ming last_name: Shen - first_name: Hongtao full_name: Shen, Hongtao last_name: Shen - first_name: Jiangang full_name: Shen, Jiangang last_name: Shen - first_name: Ming full_name: Shen, Ming last_name: Shen - first_name: Weili full_name: Shen, Weili last_name: Shen - first_name: Zheni full_name: Shen, Zheni last_name: Shen - first_name: Rui full_name: Sheng, Rui last_name: Sheng - first_name: Zhi full_name: Sheng, Zhi last_name: Sheng - first_name: Zu Hang full_name: Sheng, Zu Hang last_name: Sheng - first_name: Jianjian full_name: Shi, Jianjian last_name: Shi - first_name: Xiaobing full_name: Shi, Xiaobing last_name: Shi - first_name: Ying Hong full_name: Shi, Ying Hong last_name: Shi - first_name: Kahori full_name: Shiba-Fukushima, Kahori last_name: Shiba-Fukushima - first_name: Jeng Jer full_name: Shieh, Jeng Jer last_name: Shieh - first_name: Yohta full_name: Shimada, Yohta last_name: Shimada - first_name: Shigeomi full_name: Shimizu, Shigeomi last_name: Shimizu - first_name: Makoto full_name: Shimozawa, Makoto last_name: Shimozawa - first_name: Takahiro full_name: Shintani, Takahiro last_name: Shintani - first_name: Christopher J. full_name: Shoemaker, Christopher J. last_name: Shoemaker - first_name: Shahla full_name: Shojaei, Shahla last_name: Shojaei - first_name: Ikuo full_name: Shoji, Ikuo last_name: Shoji - first_name: Bhupendra V. full_name: Shravage, Bhupendra V. last_name: Shravage - first_name: Viji full_name: Shridhar, Viji last_name: Shridhar - first_name: Chih Wen full_name: Shu, Chih Wen last_name: Shu - first_name: Hong Bing full_name: Shu, Hong Bing last_name: Shu - first_name: Ke full_name: Shui, Ke last_name: Shui - first_name: Arvind K. full_name: Shukla, Arvind K. last_name: Shukla - first_name: Timothy E. full_name: Shutt, Timothy E. last_name: Shutt - first_name: Valentina full_name: Sica, Valentina last_name: Sica - first_name: Aleem full_name: Siddiqui, Aleem last_name: Siddiqui - first_name: Amanda full_name: Sierra, Amanda last_name: Sierra - first_name: Virginia full_name: Sierra-Torre, Virginia last_name: Sierra-Torre - first_name: Santiago full_name: Signorelli, Santiago last_name: Signorelli - first_name: Payel full_name: Sil, Payel last_name: Sil - first_name: Bruno J.De Andrade full_name: Silva, Bruno J.De Andrade last_name: Silva - first_name: Johnatas D. full_name: Silva, Johnatas D. last_name: Silva - first_name: Eduardo full_name: Silva-Pavez, Eduardo last_name: Silva-Pavez - first_name: Sandrine full_name: Silvente-Poirot, Sandrine last_name: Silvente-Poirot - first_name: Rachel E. full_name: Simmonds, Rachel E. last_name: Simmonds - first_name: Anna Katharina full_name: Simon, Anna Katharina last_name: Simon - first_name: Hans Uwe full_name: Simon, Hans Uwe last_name: Simon - first_name: Matias full_name: Simons, Matias last_name: Simons - first_name: Anurag full_name: Singh, Anurag last_name: Singh - first_name: Lalit P. full_name: Singh, Lalit P. last_name: Singh - first_name: Rajat full_name: Singh, Rajat last_name: Singh - first_name: Shivendra V. full_name: Singh, Shivendra V. last_name: Singh - first_name: Shrawan K. full_name: Singh, Shrawan K. last_name: Singh - first_name: Sudha B. full_name: Singh, Sudha B. last_name: Singh - first_name: Sunaina full_name: Singh, Sunaina last_name: Singh - first_name: Surinder Pal full_name: Singh, Surinder Pal last_name: Singh - first_name: Debasish full_name: Sinha, Debasish last_name: Sinha - first_name: Rohit Anthony full_name: Sinha, Rohit Anthony last_name: Sinha - first_name: Sangita full_name: Sinha, Sangita last_name: Sinha - first_name: Agnieszka full_name: Sirko, Agnieszka last_name: Sirko - first_name: Kapil full_name: Sirohi, Kapil last_name: Sirohi - first_name: Efthimios L. full_name: Sivridis, Efthimios L. last_name: Sivridis - first_name: Panagiotis full_name: Skendros, Panagiotis last_name: Skendros - first_name: Aleksandra full_name: Skirycz, Aleksandra last_name: Skirycz - first_name: Iva full_name: Slaninová, Iva last_name: Slaninová - first_name: Soraya S. full_name: Smaili, Soraya S. last_name: Smaili - first_name: Andrei full_name: Smertenko, Andrei last_name: Smertenko - first_name: Matthew D. full_name: Smith, Matthew D. last_name: Smith - first_name: Stefaan J. full_name: Soenen, Stefaan J. last_name: Soenen - first_name: Eun Jung full_name: Sohn, Eun Jung last_name: Sohn - first_name: Sophia P.M. full_name: Sok, Sophia P.M. last_name: Sok - first_name: Giancarlo full_name: Solaini, Giancarlo last_name: Solaini - first_name: Thierry full_name: Soldati, Thierry last_name: Soldati - first_name: Scott A. full_name: Soleimanpour, Scott A. last_name: Soleimanpour - first_name: Rosa M. full_name: Soler, Rosa M. last_name: Soler - first_name: Alexei full_name: Solovchenko, Alexei last_name: Solovchenko - first_name: Jason A. full_name: Somarelli, Jason A. last_name: Somarelli - first_name: Avinash full_name: Sonawane, Avinash last_name: Sonawane - first_name: Fuyong full_name: Song, Fuyong last_name: Song - first_name: Hyun Kyu full_name: Song, Hyun Kyu last_name: Song - first_name: Ju Xian full_name: Song, Ju Xian last_name: Song - first_name: Kunhua full_name: Song, Kunhua last_name: Song - first_name: Zhiyin full_name: Song, Zhiyin last_name: Song - first_name: Leandro R. full_name: Soria, Leandro R. last_name: Soria - first_name: Maurizio full_name: Sorice, Maurizio last_name: Sorice - first_name: Alexander A. full_name: Soukas, Alexander A. last_name: Soukas - first_name: Sandra Fausia full_name: Soukup, Sandra Fausia last_name: Soukup - first_name: Diana full_name: Sousa, Diana last_name: Sousa - first_name: Nadia full_name: Sousa, Nadia last_name: Sousa - first_name: Paul A. full_name: Spagnuolo, Paul A. last_name: Spagnuolo - 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Thirumalaikumar, S.M. Thomas, P.G. Thomes, A. Thorburn, L. Thukral, T. Thum, M. Thumm, L. Tian, A. Tichy, A. Till, V. Timmerman, V.I. Titorenko, S.V. Todi, K. Todorova, J.M. Toivonen, L. Tomaipitinca, D. Tomar, C. Tomas-Zapico, S. Tomić, B.C.K. Tong, C. Tong, X. Tong, S.A. Tooze, M.L. Torgersen, S. Torii, L. Torres-López, A. Torriglia, C.G. Towers, R. Towns, S. Toyokuni, V. Trajkovic, D. Tramontano, Q.G. Tran, L.H. Travassos, C.B. Trelford, S. Tremel, I.P. Trougakos, B.P. Tsao, M.P. Tschan, H.F. Tse, T.F. Tse, H. Tsugawa, A.S. Tsvetkov, D.A. Tumbarello, Y. Tumtas, M.J. Tuñón, S. Turcotte, B. Turk, V. Turk, B.J. Turner, R.I. Tuxworth, J.K. Tyler, E.V. Tyutereva, Y. Uchiyama, A. Ugun-Klusek, H.H. Uhlig, M. Ułamek-Kozioł, I.V. Ulasov, M. Umekawa, C. Ungermann, R. Unno, S. Urbe, E. Uribe-Carretero, S. Üstün, V.N. Uversky, T. Vaccari, M.I. Vaccaro, B.F. Vahsen, H. Vakifahmetoglu-Norberg, R. Valdor, M.J. Valente, A. Valko, R.B. Vallee, A.M. Valverde, G. Van Den Berghe, S. Van Der Veen, L. Van Kaer, J. Van Loosdregt, S.J.L. Van Wijk, W. Vandenberghe, I. Vanhorebeek, M.A. Vannier-Santos, N. Vannini, M.C. Vanrell, C. Vantaggiato, G. Varano, I. Varela-Nieto, M. Varga, M.H. Vasconcelos, S. Vats, D.G. Vavvas, I. Vega-Naredo, S. Vega-Rubin-De-Celis, G. Velasco, A.P. Velázquez, T. Vellai, E. Vellenga, F. Velotti, M. Verdier, P. Verginis, I. Vergne, P. Verkade, M. Verma, P. Verstreken, T. Vervliet, J. Vervoorts, A.T. Vessoni, V.M. Victor, M. Vidal, C. Vidoni, O.V. Vieira, R.D. Vierstra, S. Viganó, H. Vihinen, V. Vijayan, M. Vila, M. Vilar, J.M. Villalba, A. Villalobo, B. Villarejo-Zori, F. Villarroya, J. Villarroya, O. Vincent, C. Vindis, C. Viret, M.T. Viscomi, D. Visnjic, I. Vitale, D.J. Vocadlo, O.V. Voitsekhovskaja, C. Volonté, M. Volta, M. Vomero, C. Von Haefen, M.A. Vooijs, W. Voos, L. Vucicevic, R. Wade-Martins, S. Waguri, K.A. Waite, S. Wakatsuki, D.W. Walker, M.J. Walker, S.A. Walker, J. Walter, F.G. Wandosell, B. Wang, C.Y. Wang, C. Wang, C. Wang, C. Wang, C.Y. Wang, D. Wang, F. Wang, F. Wang, F. Wang, G. Wang, H. Wang, H. Wang, H. Wang, H.G. Wang, J. Wang, J. Wang, J. Wang, J. Wang, K. Wang, L. Wang, L. Wang, M.H. Wang, M. Wang, N. Wang, P. Wang, P. Wang, P. Wang, P. Wang, Q.J. Wang, Q. Wang, Q.K. Wang, Q.A. Wang, W.T. Wang, W. Wang, X. Wang, X. Wang, Y. Wang, Y. Wang, Y. Wang, Y.Y. Wang, Y. Wang, Y. Wang, Y. Wang, Y. Wang, Z. Wang, Z. Wang, Z. Wang, G. Warnes, V. Warnsmann, H. Watada, E. Watanabe, M. Watchon, A. Wawrzyńska, T.E. Weaver, G. Wegrzyn, A.M. Wehman, H. Wei, L. Wei, T. Wei, Y. Wei, O.H. Weiergräber, C.C. Weihl, G. Weindl, R. Weiskirchen, A. Wells, R.H. Wen, X. Wen, A. Werner, B. Weykopf, S.P. Wheatley, J.L. Whitton, A.J. Whitworth, K. Wiktorska, M.E. Wildenberg, T. Wileman, S. Wilkinson, D. Willbold, B. Williams, R.S.B. Williams, R.L. Williams, P.R. Williamson, R.A. Wilson, B. Winner, N.J. Winsor, S.S. Witkin, H. Wodrich, U. Woehlbier, T. Wollert, E. Wong, J.H. Wong, R.W. Wong, V.K.W. Wong, W.W.L. Wong, A.G. Wu, C. Wu, J. Wu, J. Wu, K.K. Wu, M. Wu, S.Y. Wu, S. Wu, S.Y. Wu, S. Wu, W.K.K. Wu, X. Wu, X. Wu, Y.W. Wu, Y. Wu, R.J. Xavier, H. Xia, L. Xia, Z. Xia, G. Xiang, J. Xiang, M. Xiang, W. Xiang, B. Xiao, G. Xiao, H. Xiao, H.T. Xiao, J. Xiao, L. Xiao, S. Xiao, Y. Xiao, B. Xie, C.M. Xie, M. Xie, Y. Xie, Z. Xie, Z. Xie, M. Xilouri, C. Xu, E. Xu, H. Xu, J. Xu, J.R. Xu, L. Xu, W.W. Xu, X. Xu, Y. Xue, S.M.S. Yakhine-Diop, M. Yamaguchi, O. Yamaguchi, A. Yamamoto, S. Yamashina, S. Yan, S.J. Yan, Z. Yan, Y. Yanagi, C. Yang, D.S. Yang, H. Yang, H.T. Yang, H. Yang, J.M. Yang, J. Yang, J. Yang, L. Yang, L. Yang, M. Yang, P.M. Yang, Q. Yang, S. Yang, S. Yang, S.F. Yang, W. Yang, W.Y. Yang, X. Yang, X. Yang, Y. Yang, Y. Yang, H. Yao, S. Yao, X. Yao, Y.G. Yao, Y.M. Yao, T. Yasui, M. Yazdankhah, P.M. Yen, C. Yi, X.M. Yin, Y. Yin, Z. Yin, Z. Yin, M. Ying, Z. Ying, C.K. Yip, S.P.T. Yiu, Y.H. Yoo, K. Yoshida, S.R. Yoshii, T. Yoshimori, B. Yousefi, B. Yu, H. Yu, J. Yu, J. Yu, L. Yu, M.L. Yu, S.W. Yu, V.C. Yu, W.H. Yu, Z. Yu, Z. Yu, J. Yuan, L.Q. Yuan, S. Yuan, S.S.F. Yuan, Y. Yuan, Z. Yuan, J. Yue, Z. Yue, J. Yun, R.L. Yung, D.N. Zacks, G. Zaffagnini, V.O. Zambelli, I. Zanella, Q.S. Zang, S. Zanivan, S. Zappavigna, P. Zaragoza, K.S. Zarbalis, A. Zarebkohan, A. Zarrouk, S.O. Zeitlin, J. Zeng, J.D. Zeng, E. Žerovnik, L. Zhan, B. Zhang, D.D. Zhang, H. Zhang, H. Zhang, H. Zhang, H. Zhang, H. Zhang, H. Zhang, H. Zhang, H.L. Zhang, J. Zhang, J. Zhang, J.P. Zhang, K.Y.B. Zhang, L.W. Zhang, L. Zhang, L. Zhang, L. Zhang, L. Zhang, M. Zhang, P. Zhang, S. Zhang, W. Zhang, X. Zhang, X.W. Zhang, X. Zhang, X. Zhang, X. Zhang, X. Zhang, X.D. Zhang, Y. Zhang, Y. Zhang, Y. Zhang, Y.D. Zhang, Y. Zhang, Y.Y. Zhang, Y. Zhang, Z. Zhang, Z. Zhang, Z. Zhang, Z. Zhang, Z. Zhang, Z. Zhang, H. Zhao, L. Zhao, S. Zhao, T. Zhao, X.F. Zhao, Y. Zhao, Y. Zhao, Y. Zhao, Y. Zhao, G. Zheng, K. Zheng, L. Zheng, S. Zheng, X.L. Zheng, Y. Zheng, Z.G. Zheng, B. Zhivotovsky, Q. Zhong, A. Zhou, B. Zhou, C. Zhou, G. Zhou, H. Zhou, H. Zhou, H. Zhou, J. Zhou, J. Zhou, J. Zhou, J. Zhou, K. Zhou, R. Zhou, X.J. Zhou, Y. Zhou, Y. Zhou, Y. Zhou, Z.Y. Zhou, Z. Zhou, B. Zhu, C. Zhu, G.Q. Zhu, H. Zhu, H. Zhu, H. Zhu, W.G. Zhu, Y. Zhu, Y. Zhu, H. Zhuang, X. Zhuang, K. Zientara-Rytter, C.M. Zimmermann, E. Ziviani, T. Zoladek, W.X. Zong, D.B. Zorov, A. Zorzano, W. Zou, Z. Zou, Z. Zou, S. Zuryn, W. Zwerschke, B. Brand-Saberi, X.C. Dong, C.S. Kenchappa, Z. Li, Y. Lin, S. Oshima, Y. Rong, J.C. Sluimer, C.L. Stallings, C.K. Tong, Autophagy 17 (2021) 1–382. date_created: 2021-03-28T22:01:44Z date_published: 2021-02-08T00:00:00Z date_updated: 2026-07-28T12:37:19Z day: '08' ddc: - '580' - '570' department: - _id: JiFr - _id: CaHe doi: 10.1080/15548627.2020.1797280 external_id: isi: - '000636121800001' pmid: - '33634751' intvolume: ' 17' isi: 1 issue: '1' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1080/15548627.2020.1797280 month: '02' oa: 1 oa_version: Published Version page: 1-382 pmid: 1 publication: Autophagy publication_identifier: eissn: - 1554-8635 issn: - 1554-8627 publication_status: published publisher: Taylor & Francis quality_controlled: '1' scopus_import: '1' status: public title: Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 17 year: '2021' ... --- OA_place: publisher OA_type: free access _id: '9168' abstract: - lang: eng text: Interspecific crossing experiments have shown that sex chromosomes play a major role in reproductive isolation between many pairs of species. However, their ability to act as reproductive barriers, which hamper interspecific genetic exchange, has rarely been evaluated quantitatively compared to Autosomes. This genome-wide limitation of gene flow is essential for understanding the complete separation of species, and thus speciation. Here, we develop a mainland-island model of secondary contact between hybridizing species of an XY (or ZW) sexual system. We obtain theoretical predictions for the frequency of introgressed alleles, and the strength of the barrier to neutral gene flow for the two types of chromosomes carrying multiple interspecific barrier loci. Theoretical predictions are obtained for scenarios where introgressed alleles are rare. We show that the same analytical expressions apply for sex chromosomes and autosomes, but with different sex-averaged effective parameters. The specific features of sex chromosomes (hemizygosity and absence of recombination in the heterogametic sex) lead to reduced levels of introgression on the X (or Z) compared to autosomes. This effect can be enhanced by certain types of sex-biased forces, but it remains overall small (except when alleles causing incompatibilities are recessive). We discuss these predictions in the light of empirical data comprising model-based tests of introgression and cline surveys in various biological systems. acknowledged_ssus: - _id: ScienComp acknowledgement: "The computations were performed with the IST Austria High-Performance Computing (HPC) Cluster and the Institut Français de Bioinformatique (IFB) Core Cluster. We are grateful to Nick Barton and Beatriz Vicoso for critical comments on the model and the manuscript. We also thank Brian Charlesworth, Stuart Baird, and an anonymous reviewer for insightful comments.\r\nC.F. was supported by an Austrian Science Foundation FWF grant (Project M 2463-B29)." article_number: iyaa025 article_processing_charge: No article_type: original author: - first_name: Christelle full_name: Fraisse, Christelle id: 32DF5794-F248-11E8-B48F-1D18A9856A87 last_name: Fraisse orcid: 0000-0001-8441-5075 - first_name: Himani full_name: Sachdeva, Himani id: 42377A0A-F248-11E8-B48F-1D18A9856A87 last_name: Sachdeva citation: ama: 'Fraisse C, Sachdeva H. The rates of introgression and barriers to genetic exchange between hybridizing species: Sex chromosomes vs autosomes. Genetics. 2021;217(2). doi:10.1093/genetics/iyaa025' apa: 'Fraisse, C., & Sachdeva, H. (2021). The rates of introgression and barriers to genetic exchange between hybridizing species: Sex chromosomes vs autosomes. Genetics. Genetics Society of America. https://doi.org/10.1093/genetics/iyaa025' chicago: 'Fraisse, Christelle, and Himani Sachdeva. “The Rates of Introgression and Barriers to Genetic Exchange between Hybridizing Species: Sex Chromosomes vs Autosomes.” Genetics. Genetics Society of America, 2021. https://doi.org/10.1093/genetics/iyaa025.' ieee: 'C. Fraisse and H. Sachdeva, “The rates of introgression and barriers to genetic exchange between hybridizing species: Sex chromosomes vs autosomes,” Genetics, vol. 217, no. 2. Genetics Society of America, 2021.' ista: 'Fraisse C, Sachdeva H. 2021. The rates of introgression and barriers to genetic exchange between hybridizing species: Sex chromosomes vs autosomes. Genetics. 217(2), iyaa025.' mla: 'Fraisse, Christelle, and Himani Sachdeva. “The Rates of Introgression and Barriers to Genetic Exchange between Hybridizing Species: Sex Chromosomes vs Autosomes.” Genetics, vol. 217, no. 2, iyaa025, Genetics Society of America, 2021, doi:10.1093/genetics/iyaa025.' short: C. Fraisse, H. Sachdeva, Genetics 217 (2021). corr_author: '1' date_created: 2021-02-18T14:41:30Z date_published: 2021-02-01T00:00:00Z date_updated: 2026-07-28T12:39:03Z day: '01' ddc: - '570' department: - _id: NiBa doi: 10.1093/genetics/iyaa025 external_id: isi: - '000637218100005' pmid: - '33724409' intvolume: ' 217' isi: 1 issue: '2' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1093/genetics/iyaa025 month: '02' oa: 1 oa_version: Published Version pmid: 1 project: - _id: 2662AADE-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: M02463 name: Sex chromosomes and species barriers publication: Genetics publication_identifier: issn: - 1943-2631 publication_status: published publisher: Genetics Society of America quality_controlled: '1' scopus_import: '1' status: public title: 'The rates of introgression and barriers to genetic exchange between hybridizing species: Sex chromosomes vs autosomes' type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 217 year: '2021' ... --- OA_place: publisher OA_type: free access _id: '9793' abstract: - lang: eng text: Astrocytes extensively infiltrate the neuropil to regulate critical aspects of synaptic development and function. This process is regulated by transcellular interactions between astrocytes and neurons via cell adhesion molecules. How astrocytes coordinate developmental processes among one another to parse out the synaptic neuropil and form non-overlapping territories is unknown. Here we identify a molecular mechanism regulating astrocyte-astrocyte interactions during development to coordinate astrocyte morphogenesis and gap junction coupling. We show that hepaCAM, a disease-linked, astrocyte-enriched cell adhesion molecule, regulates astrocyte competition for territory and morphological complexity in the developing mouse cortex. Furthermore, conditional deletion of Hepacam from developing astrocytes significantly impairs gap junction coupling between astrocytes and disrupts the balance between synaptic excitation and inhibition. Mutations in HEPACAM cause megalencephalic leukoencephalopathy with subcortical cysts in humans. Therefore, our findings suggest that disruption of astrocyte self-organization mechanisms could be an underlying cause of neural pathology. acknowledgement: This work was supported by the National Institutes of Health (R01 DA047258 and R01 NS102237 to C.E., F32 NS100392 to K.T.B.) and the Holland-Trice Brain Research Award (to C.E.). K.T.B. was supported by postdoctoral fellowships from the Foerster-Bernstein Family and The Hartwell Foundation. The Hippenmeyer lab was supported by the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovations program (725780 LinPro) to S.H. R.E. was supported by Ministerio de Ciencia y Tecnología (RTI2018-093493-B-I00). We thank the Duke Light Microscopy Core Facility, the Duke Transgenic Mouse Facility, Dr. U. Schulte for assistance with proteomic experiments, and Dr. D. Silver for critical review of the manuscript. Cartoon elements of figure panels were created using BioRender.com. article_processing_charge: No article_type: original author: - first_name: Katherine T. full_name: Baldwin, Katherine T. last_name: Baldwin - first_name: Christabel X. full_name: Tan, Christabel X. last_name: Tan - first_name: Samuel T. full_name: Strader, Samuel T. last_name: Strader - first_name: Changyu full_name: Jiang, Changyu last_name: Jiang - first_name: Justin T. full_name: Savage, Justin T. last_name: Savage - first_name: Xabier full_name: Elorza-Vidal, Xabier last_name: Elorza-Vidal - first_name: Ximena full_name: Contreras, Ximena id: 475990FE-F248-11E8-B48F-1D18A9856A87 last_name: Contreras - first_name: Thomas full_name: Rülicke, Thomas last_name: Rülicke - first_name: Simon full_name: Hippenmeyer, Simon id: 37B36620-F248-11E8-B48F-1D18A9856A87 last_name: Hippenmeyer orcid: 0000-0003-2279-1061 - first_name: Raúl full_name: Estévez, Raúl last_name: Estévez - first_name: Ru-Rong full_name: Ji, Ru-Rong last_name: Ji - first_name: Cagla full_name: Eroglu, Cagla last_name: Eroglu citation: ama: Baldwin KT, Tan CX, Strader ST, et al. HepaCAM controls astrocyte self-organization and coupling. Neuron. 2021;109(15):2427-2442.e10. doi:10.1016/j.neuron.2021.05.025 apa: Baldwin, K. T., Tan, C. X., Strader, S. T., Jiang, C., Savage, J. T., Elorza-Vidal, X., … Eroglu, C. (2021). HepaCAM controls astrocyte self-organization and coupling. Neuron. Elsevier. https://doi.org/10.1016/j.neuron.2021.05.025 chicago: Baldwin, Katherine T., Christabel X. Tan, Samuel T. Strader, Changyu Jiang, Justin T. Savage, Xabier Elorza-Vidal, Ximena Contreras, et al. “HepaCAM Controls Astrocyte Self-Organization and Coupling.” Neuron. Elsevier, 2021. https://doi.org/10.1016/j.neuron.2021.05.025. ieee: K. T. Baldwin et al., “HepaCAM controls astrocyte self-organization and coupling,” Neuron, vol. 109, no. 15. Elsevier, p. 2427–2442.e10, 2021. ista: Baldwin KT, Tan CX, Strader ST, Jiang C, Savage JT, Elorza-Vidal X, Contreras X, Rülicke T, Hippenmeyer S, Estévez R, Ji R-R, Eroglu C. 2021. HepaCAM controls astrocyte self-organization and coupling. Neuron. 109(15), 2427–2442.e10. mla: Baldwin, Katherine T., et al. “HepaCAM Controls Astrocyte Self-Organization and Coupling.” Neuron, vol. 109, no. 15, Elsevier, 2021, p. 2427–2442.e10, doi:10.1016/j.neuron.2021.05.025. short: K.T. Baldwin, C.X. Tan, S.T. Strader, C. Jiang, J.T. Savage, X. Elorza-Vidal, X. Contreras, T. Rülicke, S. Hippenmeyer, R. Estévez, R.-R. Ji, C. Eroglu, Neuron 109 (2021) 2427–2442.e10. date_created: 2021-08-06T09:08:25Z date_published: 2021-08-04T00:00:00Z date_updated: 2026-07-28T12:30:05Z day: '04' ddc: - '570' department: - _id: SiHi doi: 10.1016/j.neuron.2021.05.025 ec_funded: 1 external_id: isi: - '000692851900010' pmid: - '34171291' intvolume: ' 109' isi: 1 issue: '15' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1016/j.neuron.2021.05.025 month: '08' oa: 1 oa_version: Published Version page: 2427-2442.e10 pmid: 1 project: - _id: 260018B0-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '725780' name: Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development publication: Neuron publication_identifier: eissn: - 1097-4199 issn: - 0896-6273 publication_status: published publisher: Elsevier quality_controlled: '1' scopus_import: '1' status: public title: HepaCAM controls astrocyte self-organization and coupling type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 109 year: '2021' ... --- OA_place: publisher OA_type: free access _id: '10363' abstract: - lang: eng text: Erythropoietin enhances oxygen delivery and reduces hypoxia-induced cell death, but its pro-thrombotic activity is problematic for use of erythropoietin in treating hypoxia. We constructed a fusion protein that stimulates red blood cell production and neuroprotection without triggering platelet production, a marker for thrombosis. The protein consists of an anti-glycophorin A nanobody and an erythropoietin mutant (L108A). The mutation reduces activation of erythropoietin receptor homodimers that induce erythropoiesis and thrombosis, but maintains the tissue-protective signaling. The binding of the nanobody element to glycophorin A rescues homodimeric erythropoietin receptor activation on red blood cell precursors. In a cell proliferation assay, the fusion protein is active at 10−14 M, allowing an estimate of the number of receptor–ligand complexes needed for signaling. This fusion protein stimulates erythroid cell proliferation in vitro and in mice, and shows neuroprotective activity in vitro. Our erythropoietin fusion protein presents a novel molecule for treating hypoxia. acknowledgement: This work was supported by funds from the Wyss Institute for Biologically Inspired Engineering and the Boston Biomedical Innovation Center (Pilot Award 112475; Drive Award U54HL119145). J.L., K.M.K., D.R.B., J.C.W. and P.A.S. were supported by the Harvard Medical School Department of Systems Biology. J.C.W. was further supported by the Harvard Medical School Laboratory of Systems Pharmacology. A.V., D.R.B. and P.A.S. were further supported by the Wyss Institute for Biologically Inspired Engineering. N.G.G. was sponsored by the Army Research Office under Grant Number W911NF-17-2-0092. The views and conclusions contained in this document are those of the authors and should not be interpreted as representing the official policies, either expressed or implied, of the Army Research Office or the U.S. Government. The U.S. Government is authorized to reproduce and distribute reprints for Government purposes notwithstanding any copyright notation herein. We sincerely thank Amanda Graveline and the Wyss Institute at Harvard for their scientific support. article_number: gzab025 article_processing_charge: No article_type: original author: - first_name: Jungmin full_name: Lee, Jungmin last_name: Lee - first_name: Andyna full_name: Vernet, Andyna last_name: Vernet - first_name: Nathalie full_name: Gruber, Nathalie id: 2C9C8316-AA17-11E9-B5C2-8BC2E5697425 last_name: Gruber - first_name: Kasia M. full_name: Kready, Kasia M. last_name: Kready - first_name: Devin R. full_name: Burrill, Devin R. last_name: Burrill - first_name: Jeffrey C. full_name: Way, Jeffrey C. last_name: Way - first_name: Pamela A. full_name: Silver, Pamela A. last_name: Silver citation: ama: Lee J, Vernet A, Gruber N, et al. Rational engineering of an erythropoietin fusion protein to treat hypoxia. Protein Engineering, Design and Selection. 2021;34. doi:10.1093/protein/gzab025 apa: Lee, J., Vernet, A., Gruber, N., Kready, K. M., Burrill, D. R., Way, J. C., & Silver, P. A. (2021). Rational engineering of an erythropoietin fusion protein to treat hypoxia. Protein Engineering, Design and Selection. Oxford University Press. https://doi.org/10.1093/protein/gzab025 chicago: Lee, Jungmin, Andyna Vernet, Nathalie Gruber, Kasia M. Kready, Devin R. Burrill, Jeffrey C. Way, and Pamela A. Silver. “Rational Engineering of an Erythropoietin Fusion Protein to Treat Hypoxia.” Protein Engineering, Design and Selection. Oxford University Press, 2021. https://doi.org/10.1093/protein/gzab025. ieee: J. Lee et al., “Rational engineering of an erythropoietin fusion protein to treat hypoxia,” Protein Engineering, Design and Selection, vol. 34. Oxford University Press, 2021. ista: Lee J, Vernet A, Gruber N, Kready KM, Burrill DR, Way JC, Silver PA. 2021. Rational engineering of an erythropoietin fusion protein to treat hypoxia. Protein Engineering, Design and Selection. 34, gzab025. mla: Lee, Jungmin, et al. “Rational Engineering of an Erythropoietin Fusion Protein to Treat Hypoxia.” Protein Engineering, Design and Selection, vol. 34, gzab025, Oxford University Press, 2021, doi:10.1093/protein/gzab025. short: J. Lee, A. Vernet, N. Gruber, K.M. Kready, D.R. Burrill, J.C. Way, P.A. Silver, Protein Engineering, Design and Selection 34 (2021). date_created: 2021-11-28T23:01:28Z date_published: 2021-11-01T00:00:00Z date_updated: 2026-07-28T12:27:59Z day: '01' ddc: - '570' department: - _id: CaGu doi: 10.1093/protein/gzab025 external_id: isi: - '000746596900001' pmid: - '34725710' intvolume: ' 34' isi: 1 language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1093/protein/gzab025 month: '11' oa: 1 oa_version: Published Version pmid: 1 publication: Protein Engineering, Design and Selection publication_identifier: eissn: - 1741-0134 issn: - 1741-0126 publication_status: published publisher: Oxford University Press quality_controlled: '1' scopus_import: '1' status: public title: Rational engineering of an erythropoietin fusion protein to treat hypoxia type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 34 year: '2021' ... --- OA_type: closed access _id: '10809' abstract: - lang: eng text: Thermoelectric materials are engines that convert heat into an electrical current. Intuitively, the efficiency of this process depends on how many electrons (charge carriers) can move and how easily they do so, how much energy those moving electrons transport, and how easily the temperature gradient is maintained. In terms of material properties, an excellent thermoelectric material requires a high electrical conductivity σ, a high Seebeck coefficient S (a measure of the induced thermoelectric voltage as a function of temperature gradient), and a low thermal conductivity κ. The challenge is that these three properties are strongly interrelated in a conflicting manner (1). On page 722 of this issue, Roychowdhury et al. (2) have found a way to partially break these ties in silver antimony telluride (AgSbTe2) with the addition of cadmium (Cd) cations, which increase the ordering in this inherently disordered thermoelectric material. article_processing_charge: No article_type: letter_note author: - first_name: Yu full_name: Liu, Yu id: 2A70014E-F248-11E8-B48F-1D18A9856A87 last_name: Liu orcid: 0000-0001-7313-6740 - first_name: Maria full_name: Ibáñez, Maria id: 43C61214-F248-11E8-B48F-1D18A9856A87 last_name: Ibáñez orcid: 0000-0001-5013-2843 citation: ama: Liu Y, Ibáñez M. Tidying up the mess. Science. 2021;371(6530):678-679. doi:10.1126/science.abg0886 apa: Liu, Y., & Ibáñez, M. (2021). Tidying up the mess. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.abg0886 chicago: Liu, Yu, and Maria Ibáñez. “Tidying up the Mess.” Science. American Association for the Advancement of Science, 2021. https://doi.org/10.1126/science.abg0886. ieee: Y. Liu and M. Ibáñez, “Tidying up the mess,” Science, vol. 371, no. 6530. American Association for the Advancement of Science, pp. 678–679, 2021. ista: Liu Y, Ibáñez M. 2021. Tidying up the mess. Science. 371(6530), 678–679. mla: Liu, Yu, and Maria Ibáñez. “Tidying up the Mess.” Science, vol. 371, no. 6530, American Association for the Advancement of Science, 2021, pp. 678–79, doi:10.1126/science.abg0886. short: Y. Liu, M. Ibáñez, Science 371 (2021) 678–679. corr_author: '1' date_created: 2022-03-03T09:51:48Z date_published: 2021-02-12T00:00:00Z date_updated: 2026-07-28T12:16:17Z day: '12' department: - _id: MaIb doi: 10.1126/science.abg0886 external_id: isi: - '000617551600027' pmid: - '33574201' intvolume: ' 371' isi: 1 issue: '6530' language: - iso: eng month: '02' oa_version: None page: 678-679 pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: Tidying up the mess type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 371 year: '2021' ... --- _id: '8317' abstract: - lang: eng text: When can a polyomino piece of paper be folded into a unit cube? Prior work studied tree-like polyominoes, but polyominoes with holes remain an intriguing open problem. We present sufficient conditions for a polyomino with one or several holes to fold into a cube, and conditions under which cube folding is impossible. In particular, we show that all but five special “basic” holes guarantee foldability. acknowledgement: This research was performed in part at the 33rd Bellairs Winter Workshop on Computational Geometry. We thank all other participants for a fruitful atmosphere. H. Akitaya was supported by NSF CCF-1422311 & 1423615. Z. Masárová was partially funded by Wittgenstein Prize, Austrian Science Fund (FWF), grant no. Z 342-N31. article_number: '101700' article_processing_charge: No article_type: original arxiv: 1 author: - first_name: Oswin full_name: Aichholzer, Oswin last_name: Aichholzer - first_name: Hugo A. full_name: Akitaya, Hugo A. last_name: Akitaya - first_name: Kenneth C. full_name: Cheung, Kenneth C. last_name: Cheung - first_name: Erik D. full_name: Demaine, Erik D. last_name: Demaine - first_name: Martin L. full_name: Demaine, Martin L. last_name: Demaine - first_name: Sándor P. full_name: Fekete, Sándor P. last_name: Fekete - first_name: Linda full_name: Kleist, Linda last_name: Kleist - first_name: Irina full_name: Kostitsyna, Irina last_name: Kostitsyna - first_name: Maarten full_name: Löffler, Maarten last_name: Löffler - first_name: Zuzana full_name: Masárová, Zuzana id: 45CFE238-F248-11E8-B48F-1D18A9856A87 last_name: Masárová orcid: 0000-0002-6660-1322 - first_name: Klara full_name: Mundilova, Klara last_name: Mundilova - first_name: Christiane full_name: Schmidt, Christiane last_name: Schmidt citation: ama: 'Aichholzer O, Akitaya HA, Cheung KC, et al. Folding polyominoes with holes into a cube. Computational Geometry: Theory and Applications. 2021;93. doi:10.1016/j.comgeo.2020.101700' apa: 'Aichholzer, O., Akitaya, H. A., Cheung, K. C., Demaine, E. D., Demaine, M. L., Fekete, S. P., … Schmidt, C. (2021). Folding polyominoes with holes into a cube. Computational Geometry: Theory and Applications. Elsevier. https://doi.org/10.1016/j.comgeo.2020.101700' chicago: 'Aichholzer, Oswin, Hugo A. Akitaya, Kenneth C. Cheung, Erik D. Demaine, Martin L. Demaine, Sándor P. Fekete, Linda Kleist, et al. “Folding Polyominoes with Holes into a Cube.” Computational Geometry: Theory and Applications. Elsevier, 2021. https://doi.org/10.1016/j.comgeo.2020.101700.' ieee: 'O. Aichholzer et al., “Folding polyominoes with holes into a cube,” Computational Geometry: Theory and Applications, vol. 93. Elsevier, 2021.' ista: 'Aichholzer O, Akitaya HA, Cheung KC, Demaine ED, Demaine ML, Fekete SP, Kleist L, Kostitsyna I, Löffler M, Masárová Z, Mundilova K, Schmidt C. 2021. Folding polyominoes with holes into a cube. Computational Geometry: Theory and Applications. 93, 101700.' mla: 'Aichholzer, Oswin, et al. “Folding Polyominoes with Holes into a Cube.” Computational Geometry: Theory and Applications, vol. 93, 101700, Elsevier, 2021, doi:10.1016/j.comgeo.2020.101700.' short: 'O. Aichholzer, H.A. Akitaya, K.C. Cheung, E.D. Demaine, M.L. Demaine, S.P. Fekete, L. Kleist, I. Kostitsyna, M. Löffler, Z. Masárová, K. Mundilova, C. Schmidt, Computational Geometry: Theory and Applications 93 (2021).' corr_author: '1' date_created: 2020-08-30T22:01:09Z date_published: 2021-02-01T00:00:00Z date_updated: 2026-07-28T13:08:48Z day: '01' department: - _id: HeEd doi: 10.1016/j.comgeo.2020.101700 external_id: arxiv: - '1910.09917' isi: - '000579185100004' intvolume: ' 93' isi: 1 language: - iso: eng main_file_link: - open_access: '1' url: https://arxiv.org/abs/1910.09917v3 month: '02' oa: 1 oa_version: Preprint project: - _id: 268116B8-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: Z00342 name: Mathematics, Computer Science publication: 'Computational Geometry: Theory and Applications' publication_identifier: eissn: - 1879-081X issn: - 0925-7721 publication_status: published publisher: Elsevier quality_controlled: '1' related_material: record: - id: '6989' relation: shorter_version status: public scopus_import: '1' status: public title: Folding polyominoes with holes into a cube type: journal_article user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd volume: 93 year: '2021' ... --- OA_place: repository OA_type: green _id: '10912' abstract: - lang: eng text: Brain dynamics display collective phenomena as diverse as neuronal oscillations and avalanches. Oscillations are rhythmic, with fluctuations occurring at a characteristic scale, whereas avalanches are scale-free cascades of neural activity. Here we show that such antithetic features can coexist in a very generic class of adaptive neural networks. In the most simple yet fully microscopic model from this class we make direct contact with human brain resting-state activity recordings via tractable inference of the model's two essential parameters. The inferred model quantitatively captures the dynamics over a broad range of scales, from single sensor fluctuations, collective behaviors of nearly-synchronous extreme events on multiple sensors, to neuronal avalanches unfolding over multiple sensors across multiple time-bins. Importantly, the inferred parameters correlate with model-independent signatures of "closeness to criticality", suggesting that the coexistence of scale-specific (neural oscillations) and scale-free (neuronal avalanches) dynamics in brain activity occurs close to a non-equilibrium critical point at the onset of self-sustained oscillations. acknowledgement: "FL acknowledges support from the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie Grant Agreement No. 754411. GT\r\nacknowledges the support of the Austrian Science Fund (FWF) under Stand-Alone Grant\r\nNo. P34015." article_number: '2108.06686' article_processing_charge: No arxiv: 1 author: - first_name: Fabrizio full_name: Lombardi, Fabrizio id: A057D288-3E88-11E9-986D-0CF4E5697425 last_name: Lombardi orcid: 0000-0003-2623-5249 - first_name: Selver full_name: Pepic, Selver id: F93245C4-C3CA-11E9-B4F0-C6F4E5697425 last_name: Pepic - first_name: Oren full_name: Shriki, Oren last_name: Shriki - first_name: Gašper full_name: Tkačik, Gašper id: 3D494DCA-F248-11E8-B48F-1D18A9856A87 last_name: Tkačik orcid: 0000-0002-6699-1455 - first_name: Daniele full_name: De Martino, Daniele last_name: De Martino citation: ama: Lombardi F, Pepic S, Shriki O, Tkačik G, De Martino D. Quantifying the coexistence of neuronal oscillations and avalanches. doi:10.48550/ARXIV.2108.06686 apa: Lombardi, F., Pepic, S., Shriki, O., Tkačik, G., & De Martino, D. (n.d.). Quantifying the coexistence of neuronal oscillations and avalanches. arXiv. https://doi.org/10.48550/ARXIV.2108.06686 chicago: Lombardi, Fabrizio, Selver Pepic, Oren Shriki, Gašper Tkačik, and Daniele De Martino. “Quantifying the Coexistence of Neuronal Oscillations and Avalanches.” arXiv, n.d. https://doi.org/10.48550/ARXIV.2108.06686. ieee: F. Lombardi, S. Pepic, O. Shriki, G. Tkačik, and D. De Martino, “Quantifying the coexistence of neuronal oscillations and avalanches.” arXiv. ista: Lombardi F, Pepic S, Shriki O, Tkačik G, De Martino D. Quantifying the coexistence of neuronal oscillations and avalanches. 2108.06686. mla: Lombardi, Fabrizio, et al. Quantifying the Coexistence of Neuronal Oscillations and Avalanches. 2108.06686, arXiv, doi:10.48550/ARXIV.2108.06686. short: F. Lombardi, S. Pepic, O. Shriki, G. Tkačik, D. De Martino, (n.d.). date_created: 2022-03-21T11:41:28Z date_published: 2021-08-17T00:00:00Z date_updated: 2026-07-29T06:53:41Z day: '17' ddc: - '570' department: - _id: GaTk doi: 10.48550/ARXIV.2108.06686 ec_funded: 1 external_id: arxiv: - '2108.06686' language: - iso: eng main_file_link: - open_access: '1' url: https://arxiv.org/abs/2108.06686 month: '08' oa: 1 oa_version: Preprint project: - _id: 260C2330-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '754411' name: ISTplus - Postdoctoral Fellowships - _id: 626c45b5-2b32-11ec-9570-e509828c1ba6 grant_number: P34015 name: Efficient coding with biophysical realism publication_status: submitted publisher: arXiv related_material: record: - id: '12762' relation: later_version status: public status: public title: Quantifying the coexistence of neuronal oscillations and avalanches type: preprint user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2021' ... --- _id: '10080' abstract: - lang: eng text: Hippocampal and neocortical neural activity is modulated by the position of the individual in space. While hippocampal neurons provide the basis for a spatial map, prefrontal cortical neurons generalize over environmental features. Whether these generalized representations result from a bidirectional interaction with, or are mainly derived from hippocampal spatial representations is not known. By examining simultaneously recorded hippocampal and medial prefrontal neurons, we observed that prefrontal spatial representations show a delayed coherence with hippocampal ones. We also identified subpopulations of cells in the hippocampus and medial prefrontal cortex that formed functional cross-area couplings; these resembled the optimal connections predicted by a probabilistic model of spatial information transfer and generalization. Moreover, cross-area couplings were strongest and had the shortest delay preceding spatial decision-making. Our results suggest that generalized spatial coding in the medial prefrontal cortex is inherited from spatial representations in the hippocampus, and that the routing of information can change dynamically with behavioral demands. acknowledgement: We thank Federico Stella for invaluable suggestions and discussions. We thank Yosman BapatDhar and Andrea Cumpelik for comments, help and suggestions on the exposure of the text. We thank Predrag Živadinović and Juliana Couras for comments on the text and the figures. This work was supported by the EU-FP7 MC-ITN IN-SENS (grant 607616). article_processing_charge: No author: - first_name: Michele full_name: Nardin, Michele id: 30BD0376-F248-11E8-B48F-1D18A9856A87 last_name: Nardin orcid: 0000-0001-8849-6570 - first_name: Karola full_name: Käfer, Karola id: 2DAA49AA-F248-11E8-B48F-1D18A9856A87 last_name: Käfer - first_name: Jozsef L full_name: Csicsvari, Jozsef L id: 3FA14672-F248-11E8-B48F-1D18A9856A87 last_name: Csicsvari orcid: 0000-0002-5193-4036 biorxivid: 1 citation: ama: Nardin M, Käfer K, Csicsvari JL. The generalized spatial representation in the prefrontal cortex is inherited from the hippocampus. bioRxiv. doi:10.1101/2021.09.30.462269 apa: Nardin, M., Käfer, K., & Csicsvari, J. L. (n.d.). The generalized spatial representation in the prefrontal cortex is inherited from the hippocampus. bioRxiv. https://doi.org/10.1101/2021.09.30.462269 chicago: Nardin, Michele, Karola Käfer, and Jozsef L Csicsvari. “The Generalized Spatial Representation in the Prefrontal Cortex Is Inherited from the Hippocampus.” BioRxiv, n.d. https://doi.org/10.1101/2021.09.30.462269. ieee: M. Nardin, K. Käfer, and J. L. Csicsvari, “The generalized spatial representation in the prefrontal cortex is inherited from the hippocampus,” bioRxiv. . ista: Nardin M, Käfer K, Csicsvari JL. The generalized spatial representation in the prefrontal cortex is inherited from the hippocampus. bioRxiv, 10.1101/2021.09.30.462269. mla: Nardin, Michele, et al. “The Generalized Spatial Representation in the Prefrontal Cortex Is Inherited from the Hippocampus.” BioRxiv, doi:10.1101/2021.09.30.462269. short: M. Nardin, K. Käfer, J.L. Csicsvari, BioRxiv (n.d.). das_tickbox: '1' date_created: 2021-10-04T06:28:32Z date_published: 2021-10-02T00:00:00Z date_updated: 2026-07-29T06:33:53Z day: '02' department: - _id: GradSch - _id: JoCs doi: 10.1101/2021.09.30.462269 ec_funded: 1 external_id: biorxivid: - 10.1101/2021.09.30.462269 language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1101/2021.09.30.462269 month: '10' oa: 1 oa_version: Preprint project: - _id: 257BBB4C-B435-11E9-9278-68D0E5697425 call_identifier: FP7 grant_number: '607616' name: inter-and intracellular signalling in schizophrenia publication: bioRxiv publication_status: submitted status: public title: The generalized spatial representation in the prefrontal cortex is inherited from the hippocampus type: preprint user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2021' ... --- _id: '9905' abstract: - lang: eng text: Vaccines are thought to be the best available solution for controlling the ongoing SARS-CoV-2 pandemic. However, the emergence of vaccine-resistant strains may come too rapidly for current vaccine developments to alleviate the health, economic and social consequences of the pandemic. To quantify and characterize the risk of such a scenario, we created a SIR-derived model with initial stochastic dynamics of the vaccine-resistant strain to study the probability of its emergence and establishment. Using parameters realistically resembling SARS-CoV-2 transmission, we model a wave-like pattern of the pandemic and consider the impact of the rate of vaccination and the strength of non-pharmaceutical intervention measures on the probability of emergence of a resistant strain. As expected, we found that a fast rate of vaccination decreases the probability of emergence of a resistant strain. Counterintuitively, when a relaxation of non-pharmaceutical interventions happened at a time when most individuals of the population have already been vaccinated the probability of emergence of a resistant strain was greatly increased. Consequently, we show that a period of transmission reduction close to the end of the vaccination campaign can substantially reduce the probability of resistant strain establishment. Our results suggest that policymakers and individuals should consider maintaining non-pharmaceutical interventions and transmission-reducing behaviours throughout the entire vaccination period. acknowledgement: We thank Alexey Kondrashov, Nick Machnik, Raimundo Julian Saona Urmeneta, Gasper Tkacik and Nick Barton for fruitful discussions. We also thank participants of EvoLunch seminar at IST Austria and the internal seminar at the Banco de España for useful comments. The opinions expressed in this document are exclusively of the authors and, therefore, do not necessarily coincide with those of the Banco de España or the Eurosystem. ETD is supported by the Swiss National Science and Louis Jeantet Foundation. The work of FAK was in part supported by the ERC Consolidator Grant (771209-CharFL). article_number: '15729' article_processing_charge: Yes article_type: original author: - first_name: Simon full_name: Rella, Simon id: B4765ACA-AA38-11E9-AC9A-0930E6697425 last_name: Rella - first_name: Yuliya A. full_name: Kulikova, Yuliya A. last_name: Kulikova - first_name: Emmanouil T. full_name: Dermitzakis, Emmanouil T. last_name: Dermitzakis - first_name: Fyodor full_name: Kondrashov, Fyodor id: 44FDEF62-F248-11E8-B48F-1D18A9856A87 last_name: Kondrashov orcid: 0000-0001-8243-4694 citation: ama: Rella S, Kulikova YA, Dermitzakis ET, Kondrashov F. Rates of SARS-CoV-2 transmission and vaccination impact the fate of vaccine-resistant strains. Scientific Reports. 2021;11(1). doi:10.1038/s41598-021-95025-3 apa: Rella, S., Kulikova, Y. A., Dermitzakis, E. T., & Kondrashov, F. (2021). Rates of SARS-CoV-2 transmission and vaccination impact the fate of vaccine-resistant strains. Scientific Reports. Springer Nature. https://doi.org/10.1038/s41598-021-95025-3 chicago: Rella, Simon, Yuliya A. Kulikova, Emmanouil T. Dermitzakis, and Fyodor Kondrashov. “Rates of SARS-CoV-2 Transmission and Vaccination Impact the Fate of Vaccine-Resistant Strains.” Scientific Reports. Springer Nature, 2021. https://doi.org/10.1038/s41598-021-95025-3. ieee: S. Rella, Y. A. Kulikova, E. T. Dermitzakis, and F. Kondrashov, “Rates of SARS-CoV-2 transmission and vaccination impact the fate of vaccine-resistant strains,” Scientific Reports, vol. 11, no. 1. Springer Nature, 2021. ista: Rella S, Kulikova YA, Dermitzakis ET, Kondrashov F. 2021. Rates of SARS-CoV-2 transmission and vaccination impact the fate of vaccine-resistant strains. Scientific Reports. 11(1), 15729. mla: Rella, Simon, et al. “Rates of SARS-CoV-2 Transmission and Vaccination Impact the Fate of Vaccine-Resistant Strains.” Scientific Reports, vol. 11, no. 1, 15729, Springer Nature, 2021, doi:10.1038/s41598-021-95025-3. short: S. Rella, Y.A. Kulikova, E.T. Dermitzakis, F. Kondrashov, Scientific Reports 11 (2021). date_created: 2021-08-15T22:01:26Z date_published: 2021-07-30T00:00:00Z date_updated: 2026-07-29T12:57:49Z day: '30' ddc: - '570' - '610' department: - _id: FyKo doi: 10.1038/s41598-021-95025-3 ec_funded: 1 external_id: isi: - '000683329100001' pmid: - '34330988' file: - access_level: open_access checksum: ac86892ed17e6724c7251844da5cef5c content_type: application/pdf creator: asandaue date_created: 2021-08-16T11:36:49Z date_updated: 2021-08-16T11:36:49Z file_id: '9927' file_name: 2021_ScientificReports_Rella.pdf file_size: 3432001 relation: main_file success: 1 file_date_updated: 2021-08-16T11:36:49Z has_accepted_license: '1' intvolume: ' 11' isi: 1 issue: '1' language: - iso: eng month: '07' oa: 1 oa_version: Published Version pmid: 1 project: - _id: 26580278-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '771209' name: Characterizing the fitness landscape on population and global scales publication: Scientific Reports publication_identifier: eissn: - 2045-2322 publication_status: published publisher: Springer Nature quality_controlled: '1' related_material: link: - description: News on IST Website relation: press_release url: https://ist.ac.at/en/news/counterintuitive-dynamics-threaten-the-end-of-the-pandemic/ record: - id: '20811' relation: dissertation_contains status: public scopus_import: '1' status: public title: Rates of SARS-CoV-2 transmission and vaccination impact the fate of vaccine-resistant strains tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd volume: 11 year: '2021' ... --- OA_place: publisher _id: '9418' abstract: - lang: eng text: "Deep learning is best known for its empirical success across a wide range of applications\r\nspanning computer vision, natural language processing and speech. Of equal significance,\r\nthough perhaps less known, are its ramifications for learning theory: deep networks have\r\nbeen observed to perform surprisingly well in the high-capacity regime, aka the overfitting\r\nor underspecified regime. Classically, this regime on the far right of the bias-variance curve\r\nis associated with poor generalisation; however, recent experiments with deep networks\r\nchallenge this view.\r\n\r\nThis thesis is devoted to investigating various aspects of underspecification in deep learning.\r\nFirst, we argue that deep learning models are underspecified on two levels: a) any given\r\ntraining dataset can be fit by many different functions, and b) any given function can be\r\nexpressed by many different parameter configurations. We refer to the second kind of\r\nunderspecification as parameterisation redundancy and we precisely characterise its extent.\r\nSecond, we characterise the implicit criteria (the inductive bias) that guide learning in the\r\nunderspecified regime. Specifically, we consider a nonlinear but tractable classification\r\nsetting, and show that given the choice, neural networks learn classifiers with a large margin.\r\nThird, we consider learning scenarios where the inductive bias is not by itself sufficient to\r\ndeal with underspecification. We then study different ways of ‘tightening the specification’: i)\r\nIn the setting of representation learning with variational autoencoders, we propose a hand-\r\ncrafted regulariser based on mutual information. ii) In the setting of binary classification, we\r\nconsider soft-label (real-valued) supervision. We derive a generalisation bound for linear\r\nnetworks supervised in this way and verify that soft labels facilitate fast learning. Finally, we\r\nexplore an application of soft-label supervision to the training of multi-exit models." acknowledged_ssus: - _id: ScienComp - _id: CampIT - _id: E-Lib alternative_title: - ISTA Thesis article_processing_charge: No author: - first_name: Phuong full_name: Bui Thi Mai, Phuong id: 3EC6EE64-F248-11E8-B48F-1D18A9856A87 last_name: Bui Thi Mai citation: ama: Phuong M. Underspecification in deep learning. 2021. doi:10.15479/AT:ISTA:9418 apa: Phuong, M. (2021). Underspecification in deep learning. Institute of Science and Technology Austria. https://doi.org/10.15479/AT:ISTA:9418 chicago: Phuong, Mary. “Underspecification in Deep Learning.” Institute of Science and Technology Austria, 2021. https://doi.org/10.15479/AT:ISTA:9418. ieee: M. Phuong, “Underspecification in deep learning,” Institute of Science and Technology Austria, 2021. ista: Phuong M. 2021. Underspecification in deep learning. Institute of Science and Technology Austria. mla: Phuong, Mary. Underspecification in Deep Learning. Institute of Science and Technology Austria, 2021, doi:10.15479/AT:ISTA:9418. short: M. Phuong, Underspecification in Deep Learning, Institute of Science and Technology Austria, 2021. corr_author: '1' date_created: 2021-05-24T13:06:23Z date_published: 2021-05-30T00:00:00Z date_updated: 2026-07-30T05:33:52Z day: '30' ddc: - '000' degree_awarded: PhD department: - _id: GradSch - _id: ChLa doi: 10.15479/AT:ISTA:9418 doi_confirm: '1' file: - access_level: open_access checksum: 4f0abe64114cfed264f9d36e8d1197e3 content_type: application/pdf creator: bphuong date_created: 2021-05-24T11:22:29Z date_updated: 2021-05-24T11:22:29Z file_id: '9419' file_name: mph-thesis-v519-pdfimages.pdf file_size: 2673905 relation: main_file success: 1 - access_level: closed checksum: f5699e876bc770a9b0df8345a77720a2 content_type: application/zip creator: bphuong date_created: 2021-05-24T11:56:02Z date_updated: 2021-05-24T11:56:02Z file_id: '9420' file_name: thesis.zip file_size: 92995100 relation: source_file file_date_updated: 2021-05-24T11:56:02Z has_accepted_license: '1' language: - iso: eng month: '05' oa: 1 oa_version: Published Version page: '125' publication_identifier: issn: - 2663-337X publication_status: published publisher: Institute of Science and Technology Austria related_material: record: - id: '7435' relation: part_of_dissertation status: deleted - id: '7481' relation: part_of_dissertation status: public - id: '9416' relation: part_of_dissertation status: public - id: '7479' relation: part_of_dissertation status: public status: public supervisor: - first_name: Christoph full_name: Lampert, Christoph id: 40C20FD2-F248-11E8-B48F-1D18A9856A87 last_name: Lampert orcid: 0000-0001-8622-7887 title: Underspecification in deep learning type: dissertation user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9 year: '2021' ... --- _id: '9416' abstract: - lang: eng text: 'We study the inductive bias of two-layer ReLU networks trained by gradient flow. We identify a class of easy-to-learn (`orthogonally separable'') datasets, and characterise the solution that ReLU networks trained on such datasets converge to. Irrespective of network width, the solution turns out to be a combination of two max-margin classifiers: one corresponding to the positive data subset and one corresponding to the negative data subset. The proof is based on the recently introduced concept of extremal sectors, for which we prove a number of properties in the context of orthogonal separability. In particular, we prove stationarity of activation patterns from some time onwards, which enables a reduction of the ReLU network to an ensemble of linear subnetworks.' article_processing_charge: No author: - first_name: Phuong full_name: Bui Thi Mai, Phuong id: 3EC6EE64-F248-11E8-B48F-1D18A9856A87 last_name: Bui Thi Mai - first_name: Christoph full_name: Lampert, Christoph id: 40C20FD2-F248-11E8-B48F-1D18A9856A87 last_name: Lampert orcid: 0000-0001-8622-7887 citation: ama: 'Phuong M, Lampert C. The inductive bias of ReLU networks on orthogonally separable data. In: 9th International Conference on Learning Representations. ; 2021.' apa: Phuong, M., & Lampert, C. (2021). The inductive bias of ReLU networks on orthogonally separable data. In 9th International Conference on Learning Representations. Virtual. chicago: Phuong, Mary, and Christoph Lampert. “The Inductive Bias of ReLU Networks on Orthogonally Separable Data.” In 9th International Conference on Learning Representations, 2021. ieee: M. Phuong and C. Lampert, “The inductive bias of ReLU networks on orthogonally separable data,” in 9th International Conference on Learning Representations, Virtual, 2021. ista: 'Phuong M, Lampert C. 2021. The inductive bias of ReLU networks on orthogonally separable data. 9th International Conference on Learning Representations. ICLR: International Conference on Learning Representations.' mla: Phuong, Mary, and Christoph Lampert. “The Inductive Bias of ReLU Networks on Orthogonally Separable Data.” 9th International Conference on Learning Representations, 2021. short: M. Phuong, C. Lampert, in:, 9th International Conference on Learning Representations, 2021. conference: end_date: 2021-05-07 location: Virtual name: 'ICLR: International Conference on Learning Representations' start_date: 2021-05-03 corr_author: '1' date_created: 2021-05-24T11:16:46Z date_published: 2021-05-01T00:00:00Z date_updated: 2026-07-30T05:33:51Z day: '01' ddc: - '000' department: - _id: GradSch - _id: ChLa file: - access_level: open_access checksum: f34ff17017527db5ba6927f817bdd125 content_type: application/pdf creator: bphuong date_created: 2021-05-24T11:15:57Z date_updated: 2021-05-24T11:15:57Z file_id: '9417' file_name: iclr2021_conference.pdf file_size: 502356 relation: main_file file_date_updated: 2021-05-24T11:15:57Z has_accepted_license: '1' language: - iso: eng main_file_link: - open_access: '1' url: https://openreview.net/pdf?id=krz7T0xU9Z_ month: '05' oa: 1 oa_version: Published Version publication: 9th International Conference on Learning Representations publication_status: published quality_controlled: '1' related_material: record: - id: '9418' relation: dissertation_contains status: public scopus_import: '1' status: public title: The inductive bias of ReLU networks on orthogonally separable data type: conference user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2021' ... --- OA_place: publisher OA_type: hybrid _id: '22472' abstract: - lang: eng text: "Increasing urban tree cover is an often proposed mitigation strategy against urban heat as trees are expected to cool cities through evapotranspiration and shade provision. However, trees also modify wind flow and urban aerodynamic roughness, which can potentially limit heat dissipation. Existing studies show a varying cooling potential of urban trees in different climates and times of the day. These differences are so far not systematically explained as partitioning the individual tree effects is challenging and impossible through observations alone. Here, we conduct numerical experiments removing and adding radiation, evapotranspiration, and aerodynamic roughness effects caused by urban trees using a mechanistic urban ecohydrological model. Simulations are presented for four cities in different climates (Phoenix, Singapore, Melbourne, Zurich) considering the seasonal and diurnal cycles of air and surface temperatures.\r\nResults show that evapotranspiration of well-watered trees alone can decrease local 2 m air temperature at maximum by 3.1– 5.8 °C in the four climates during summer. Further cooling is prevented by stomatal closure at peak temperatures as high vapour pressure deficits limit transpiration. While shading reduces surface temperatures, the interaction of a non-transpiring tree with radiation can increase 2 m air temperature by up to 1.6 – 2.1 °C in certain hours of the day at local scale, thus partially counteracting the evapotranspirative cooling effect. Furthermore, in the analysed scenarios, which do not account for tree wind blockage effects, trees lead to a decrease in urban roughness, which inhibits turbulent energy exchange and increases air temperature during daytime. At night, single tree effects are variable likely due to differences in atmospheric stability within the urban canyon. These results explain reported diurnal, seasonal and climatic differences in the cooling effects of urban trees, and can guide future field campaigns, planning strategies, and species selection aimed at improving local microclimate using urban greenery." article_number: '126970' article_processing_charge: Yes (in subscription journal) article_type: original author: - first_name: Naika full_name: Meili, Naika last_name: Meili - first_name: Gabriele full_name: Manoli, Gabriele last_name: Manoli - first_name: Paolo full_name: Burlando, Paolo last_name: Burlando - first_name: Jan full_name: Carmeliet, Jan last_name: Carmeliet - first_name: Winston T.L. full_name: Chow, Winston T.L. last_name: Chow - first_name: Andrew M. full_name: Coutts, Andrew M. last_name: Coutts - first_name: Matthias full_name: Roth, Matthias last_name: Roth - first_name: Erik full_name: Velasco, Erik last_name: Velasco - first_name: Enrique R. full_name: Vivoni, Enrique R. last_name: Vivoni - first_name: Simone full_name: Fatichi, Simone id: cf8e546b-a9b0-11f0-a43b-aa89ed1b56d6 last_name: Fatichi citation: ama: 'Meili N, Manoli G, Burlando P, et al. Tree effects on urban microclimate: Diurnal, seasonal, and climatic temperature differences explained by separating radiation, evapotranspiration, and roughness effects. Urban Forestry & Urban Greening. 2021;58(3). doi:10.1016/j.ufug.2020.126970' apa: 'Meili, N., Manoli, G., Burlando, P., Carmeliet, J., Chow, W. T. L., Coutts, A. M., … Fatichi, S. (2021). Tree effects on urban microclimate: Diurnal, seasonal, and climatic temperature differences explained by separating radiation, evapotranspiration, and roughness effects. Urban Forestry & Urban Greening. Elsevier. https://doi.org/10.1016/j.ufug.2020.126970' chicago: 'Meili, Naika, Gabriele Manoli, Paolo Burlando, Jan Carmeliet, Winston T.L. Chow, Andrew M. Coutts, Matthias Roth, Erik Velasco, Enrique R. Vivoni, and Simone Fatichi. “Tree Effects on Urban Microclimate: Diurnal, Seasonal, and Climatic Temperature Differences Explained by Separating Radiation, Evapotranspiration, and Roughness Effects.” Urban Forestry & Urban Greening. Elsevier, 2021. https://doi.org/10.1016/j.ufug.2020.126970.' ieee: 'N. Meili et al., “Tree effects on urban microclimate: Diurnal, seasonal, and climatic temperature differences explained by separating radiation, evapotranspiration, and roughness effects,” Urban Forestry & Urban Greening, vol. 58, no. 3. Elsevier, 2021.' ista: 'Meili N, Manoli G, Burlando P, Carmeliet J, Chow WTL, Coutts AM, Roth M, Velasco E, Vivoni ER, Fatichi S. 2021. Tree effects on urban microclimate: Diurnal, seasonal, and climatic temperature differences explained by separating radiation, evapotranspiration, and roughness effects. Urban Forestry & Urban Greening. 58(3), 126970.' mla: 'Meili, Naika, et al. “Tree Effects on Urban Microclimate: Diurnal, Seasonal, and Climatic Temperature Differences Explained by Separating Radiation, Evapotranspiration, and Roughness Effects.” Urban Forestry & Urban Greening, vol. 58, no. 3, 126970, Elsevier, 2021, doi:10.1016/j.ufug.2020.126970.' short: N. Meili, G. Manoli, P. Burlando, J. Carmeliet, W.T.L. Chow, A.M. Coutts, M. Roth, E. Velasco, E.R. Vivoni, S. Fatichi, Urban Forestry & Urban Greening 58 (2021). das_tickbox: '1' date_created: 2026-07-27T12:30:23Z date_published: 2021-03-01T00:00:00Z date_updated: 2026-07-30T08:40:12Z day: '01' ddc: - '550' doi: 10.1016/j.ufug.2020.126970 extern: '1' has_accepted_license: '1' intvolume: ' 58' issue: '3' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1016/j.ufug.2020.126970 month: '03' oa: 1 oa_version: Published Version publication: Urban Forestry & Urban Greening publication_identifier: eissn: - 1610-8167 issn: - 1618-8667 publication_status: published publisher: Elsevier quality_controlled: '1' scopus_import: '1' status: public title: 'Tree effects on urban microclimate: Diurnal, seasonal, and climatic temperature differences explained by separating radiation, evapotranspiration, and roughness effects' tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 58 year: '2021' ... --- OA_place: publisher OA_type: hybrid _id: '22474' abstract: - lang: eng text: In light of globally increasing temperatures, accentuated in cities by the urban heat island effect, urban planners and designers are looking for new, quantitative methods to assess the performance of their designs in terms of ecosystem services provided by vegetation. Among these ecosystem services, improved microclimate conditions are particularly important for human thermal comfort and health. In this study, an urban scene in the tropical city of Singapore is numerically investigated with a fully-integrated, three-dimensional urban microclimate model implemented in OpenFOAM. Mass and heat transport in air and storage effect in the urban environment are coupled so that the daily turbulent transport in air using steady Reynolds-averaged Navier-Stokes (RANS) can be solved iteratively with the unsteady heat and moisture transfer from urban surfaces. Vegetation is modeled as a porous medium for the flow of moist air and a leaf energy balance model is used to determine the heat fluxes and transpiration at leaf surfaces. The analysis shows the influence of an urban park upon air temperatures and thermal comfort. Cooling intensity of 1 °C is observed downwind of the park within a region of 27 m for an incoming wind speed of 2.3 m s−1, which reduces to 0.6 °C at a distance of 117 m from the park. The Universal Thermal Comfort Index (UTCI) shows a reduction in thermal stress in and around the park. The approach presented here can provide specific guidelines for urban planners and frame expectations on magnitude and spatial extent of local microclimate modifications generated by an urban park in a tropical city. article_number: '100939' article_processing_charge: No article_type: original author: - first_name: Muhammad Omer full_name: Mughal, Muhammad Omer last_name: Mughal - first_name: Aytac full_name: Kubilay, Aytac last_name: Kubilay - first_name: Simone full_name: Fatichi, Simone id: cf8e546b-a9b0-11f0-a43b-aa89ed1b56d6 last_name: Fatichi - first_name: Naika full_name: Meili, Naika last_name: Meili - first_name: Jan full_name: Carmeliet, Jan last_name: Carmeliet - first_name: Peter full_name: Edwards, Peter last_name: Edwards - first_name: Paolo full_name: Burlando, Paolo last_name: Burlando citation: ama: Mughal MO, Kubilay A, Fatichi S, et al. Detailed investigation of vegetation effects on microclimate by means of computational fluid dynamics (CFD) in a tropical urban environment. Urban Climate. 2021;39. doi:10.1016/j.uclim.2021.100939 apa: Mughal, M. O., Kubilay, A., Fatichi, S., Meili, N., Carmeliet, J., Edwards, P., & Burlando, P. (2021). Detailed investigation of vegetation effects on microclimate by means of computational fluid dynamics (CFD) in a tropical urban environment. Urban Climate. Elsevier. https://doi.org/10.1016/j.uclim.2021.100939 chicago: Mughal, Muhammad Omer, Aytac Kubilay, Simone Fatichi, Naika Meili, Jan Carmeliet, Peter Edwards, and Paolo Burlando. “Detailed Investigation of Vegetation Effects on Microclimate by Means of Computational Fluid Dynamics (CFD) in a Tropical Urban Environment.” Urban Climate. Elsevier, 2021. https://doi.org/10.1016/j.uclim.2021.100939. ieee: M. O. Mughal et al., “Detailed investigation of vegetation effects on microclimate by means of computational fluid dynamics (CFD) in a tropical urban environment,” Urban Climate, vol. 39. Elsevier, 2021. ista: Mughal MO, Kubilay A, Fatichi S, Meili N, Carmeliet J, Edwards P, Burlando P. 2021. Detailed investigation of vegetation effects on microclimate by means of computational fluid dynamics (CFD) in a tropical urban environment. Urban Climate. 39, 100939. mla: Mughal, Muhammad Omer, et al. “Detailed Investigation of Vegetation Effects on Microclimate by Means of Computational Fluid Dynamics (CFD) in a Tropical Urban Environment.” Urban Climate, vol. 39, 100939, Elsevier, 2021, doi:10.1016/j.uclim.2021.100939. short: M.O. Mughal, A. Kubilay, S. Fatichi, N. Meili, J. Carmeliet, P. Edwards, P. Burlando, Urban Climate 39 (2021). das_tickbox: '1' date_created: 2026-07-27T12:30:23Z date_published: 2021-09-01T00:00:00Z date_updated: 2026-07-30T09:08:16Z day: '01' ddc: - '550' doi: 10.1016/j.uclim.2021.100939 extern: '1' has_accepted_license: '1' intvolume: ' 39' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1016/j.uclim.2021.100939 month: '09' oa: 1 oa_version: Published Version publication: Urban Climate publication_identifier: eissn: - 2212-0955 publication_status: published publisher: Elsevier quality_controlled: '1' scopus_import: '1' status: public title: Detailed investigation of vegetation effects on microclimate by means of computational fluid dynamics (CFD) in a tropical urban environment tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 39 year: '2021' ... --- OA_type: closed access _id: '22468' abstract: - lang: eng text: Vegetation establishment, growth and succession in riparian ecosystems are linked to river flow dynamics and groundwater table fluctuations. This is especially true in Alpine gravel-bed rivers with wide floodplains, geomorphically active floods and a strong river-aquifer exchange. The role of short-term groundwater fluctuations is not always clear in these ecosystems, as it is assumed that phreatophytic vegetation close to rivers is adapted to such conditions. Here, we provide data evidence of riparian plant response to short-term groundwater table fluctuations in a braided gravel-bed river (Maggia). We used indirect physiological variables for photosynthesis and transpiration—stomatal conductance gs and daily variation in stem diameter ΔDd—which we measured at six mature riparian trees of the Salicaceae family at two sites with different mean depths to groundwater during two growing seasons. The data demonstrate that (a) short-term variation of the groundwater table affects riparian vegetation—at the site with deeper groundwater, the water table depth was the best predictor of gs variability, while at the site with shallower groundwater, temperature and vapour pressure deficit (VPD) were the best predictors of ΔDd variability; (b) instantaneous stomatal conductance is related to VPD, but conditioned by groundwater levels, with higher stomatal conductance for the same radiative input and VPD when the water table was higher for all trees; and (c) local microclimate measured at tree locations had a stronger predictive power for gs than valley scale climate, suggesting local climate controls on vegetated stands on gravel bars. Our results provide evidence of riparian trees undertaking physiological adjustments to transpiration in response to groundwater stage, depending on their riparian floodplain setting. article_number: e2264 article_processing_charge: No article_type: original author: - first_name: Stefano full_name: Martinetti, Stefano last_name: Martinetti - first_name: Simone full_name: Fatichi, Simone id: cf8e546b-a9b0-11f0-a43b-aa89ed1b56d6 last_name: Fatichi - first_name: Marius full_name: Floriancic, Marius last_name: Floriancic - first_name: Paolo full_name: Burlando, Paolo last_name: Burlando - first_name: Peter full_name: Molnar, Peter last_name: Molnar citation: ama: Martinetti S, Fatichi S, Floriancic M, Burlando P, Molnar P. Field evidence of riparian vegetation response to groundwater levels in a gravel‐bed river. Ecohydrology. 2021;14(2). doi:10.1002/eco.2264 apa: Martinetti, S., Fatichi, S., Floriancic, M., Burlando, P., & Molnar, P. (2021). Field evidence of riparian vegetation response to groundwater levels in a gravel‐bed river. Ecohydrology. Wiley. https://doi.org/10.1002/eco.2264 chicago: Martinetti, Stefano, Simone Fatichi, Marius Floriancic, Paolo Burlando, and Peter Molnar. “Field Evidence of Riparian Vegetation Response to Groundwater Levels in a Gravel‐bed River.” Ecohydrology. Wiley, 2021. https://doi.org/10.1002/eco.2264. ieee: S. Martinetti, S. Fatichi, M. Floriancic, P. Burlando, and P. Molnar, “Field evidence of riparian vegetation response to groundwater levels in a gravel‐bed river,” Ecohydrology, vol. 14, no. 2. Wiley, 2021. ista: Martinetti S, Fatichi S, Floriancic M, Burlando P, Molnar P. 2021. Field evidence of riparian vegetation response to groundwater levels in a gravel‐bed river. Ecohydrology. 14(2), e2264. mla: Martinetti, Stefano, et al. “Field Evidence of Riparian Vegetation Response to Groundwater Levels in a Gravel‐bed River.” Ecohydrology, vol. 14, no. 2, e2264, Wiley, 2021, doi:10.1002/eco.2264. short: S. Martinetti, S. Fatichi, M. Floriancic, P. Burlando, P. Molnar, Ecohydrology 14 (2021). das_tickbox: '1' date_created: 2026-07-27T12:30:23Z date_published: 2021-03-01T00:00:00Z date_updated: 2026-07-30T08:46:20Z day: '01' doi: 10.1002/eco.2264 extern: '1' intvolume: ' 14' issue: '2' language: - iso: eng month: '03' oa_version: None publication: Ecohydrology publication_identifier: eissn: - 1936-0592 issn: - 1936-0584 publication_status: published publisher: Wiley quality_controlled: '1' scopus_import: '1' status: public title: Field evidence of riparian vegetation response to groundwater levels in a gravel‐bed river type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 14 year: '2021' ... --- OA_type: closed access _id: '22430' abstract: - lang: eng text: Research to detect changes in precipitation variables has become a topic of particular interest to understand modifications in water resources availability. The review is focused on the Italian territory, outlining the “state of the art” of changes in precipitation regime through a review of 54 published studies on observed rainfall trend analyses, in the period 1999–2018. The aim is to combine a large body of knowledge in a single review and to explain the main patterns of rainfall changes occurred in Italy over the last decades. The analysis focused on the Total Precipitation (TP) and the number of Wet Days (WDs) indices at the annual and seasonal scale. A weight factor is introduced to take into account the differences among studies in geographical area, time series length, and number of stations. The review is accompanied by the discussion of other rainfall related variables, that is, precipitation intensity, extreme rainfall events and meteorological droughts, which are useful to provide a broader picture of rainfall changes. Overall, there is an agreement about the tendency of a decrease in wet days on the entire Italy, with limited discrepancies in the various regions. A decrease in wet days is accompanied by a negative trend (although less evident) in total precipitation, especially in winter. Nevertheless, a univocal direction of trends (or lack of thereof) in annual total precipitation and mostly hydrological extreme events is difficult to achieve. article_processing_charge: No article_type: original author: - first_name: Enrica full_name: Caporali, Enrica last_name: Caporali - first_name: Marco full_name: Lompi, Marco last_name: Lompi - first_name: Tommaso full_name: Pacetti, Tommaso last_name: Pacetti - first_name: Valentina full_name: Chiarello, Valentina last_name: Chiarello - first_name: Simone full_name: Fatichi, Simone id: cf8e546b-a9b0-11f0-a43b-aa89ed1b56d6 last_name: Fatichi citation: ama: Caporali E, Lompi M, Pacetti T, Chiarello V, Fatichi S. A review of studies on observed precipitation trends in Italy. International Journal of Climatology. 2021;41(S1):E1-E25. doi:10.1002/joc.6741 apa: Caporali, E., Lompi, M., Pacetti, T., Chiarello, V., & Fatichi, S. (2021). A review of studies on observed precipitation trends in Italy. International Journal of Climatology. Wiley. https://doi.org/10.1002/joc.6741 chicago: Caporali, Enrica, Marco Lompi, Tommaso Pacetti, Valentina Chiarello, and Simone Fatichi. “A Review of Studies on Observed Precipitation Trends in Italy.” International Journal of Climatology. Wiley, 2021. https://doi.org/10.1002/joc.6741. ieee: E. Caporali, M. Lompi, T. Pacetti, V. Chiarello, and S. Fatichi, “A review of studies on observed precipitation trends in Italy,” International Journal of Climatology, vol. 41, no. S1. Wiley, pp. E1–E25, 2021. ista: Caporali E, Lompi M, Pacetti T, Chiarello V, Fatichi S. 2021. A review of studies on observed precipitation trends in Italy. International Journal of Climatology. 41(S1), E1–E25. mla: Caporali, Enrica, et al. “A Review of Studies on Observed Precipitation Trends in Italy.” International Journal of Climatology, vol. 41, no. S1, Wiley, 2021, pp. E1–25, doi:10.1002/joc.6741. short: E. Caporali, M. Lompi, T. Pacetti, V. Chiarello, S. Fatichi, International Journal of Climatology 41 (2021) E1–E25. das_tickbox: '1' date_created: 2026-07-27T12:30:23Z date_published: 2021-01-01T00:00:00Z date_updated: 2026-07-30T09:04:34Z day: '01' doi: 10.1002/joc.6741 extern: '1' intvolume: ' 41' issue: S1 language: - iso: eng month: '01' oa_version: None page: E1-E25 publication: International Journal of Climatology publication_identifier: eissn: - 1097-0088 issn: - 0899-8418 publication_status: published publisher: Wiley quality_controlled: '1' scopus_import: '1' status: public title: A review of studies on observed precipitation trends in Italy type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 41 year: '2021' ... --- OA_place: publisher OA_type: hybrid _id: '22457' abstract: - lang: eng text: "An increase in urban vegetation is an often proposed mitigation strategy to reduce urban heat and improve outdoor thermal comfort (OTC). Vegetation can alter urban microclimate through changes in air temperature, mean radiant temperature, humidity, and wind speed. In this study, we model how street tree and ground vegetation cover and their structural, optical, interception, and physiological traits control the diurnal cycle of OTC in different urban densities in a tropical city (Singapore). For this purpose, we perform a variance based sensitivity analysis of the urban ecohydrological model UT&C. Model performance is evaluated through a comparison with local microclimate measurements and OTC is assessed with the Universal Thermal Climate Index (UTCI).\r\nWe find a pronounced daily cycle of vegetation effects on UTCI. Tree cover fraction is more efficient in decreasing UTCI during daytime, while a higher vegetated ground fraction provides more cooling during night. Generally, increasing vegetation cover fractions do not deter OTC, except in certain urban densities during some periods of the day. An increase in tree and ground vegetation fractions provides a higher average UTCI reduction compared to a change in vegetation traits (0.9 – 2.9 °C vs. 0.7 – 1.1 °C during midday, 10 month average). The increase in humidity related to plant transpiration prevents further reduction of UTCI. However, the choice of vegetation traits enhancing tree transpiration can decrease UTCI during hot periods. These results can inform urban planners on the selection of vegetation amount and traits to achieve feasible OTC improvements in tropical cities." article_number: '107733' article_processing_charge: No article_type: original author: - first_name: Naika full_name: Meili, Naika last_name: Meili - first_name: Juan Angel full_name: Acero, Juan Angel last_name: Acero - first_name: Nadav full_name: Peleg, Nadav last_name: Peleg - first_name: Gabriele full_name: Manoli, Gabriele last_name: Manoli - first_name: Paolo full_name: Burlando, Paolo last_name: Burlando - first_name: Simone full_name: Fatichi, Simone id: cf8e546b-a9b0-11f0-a43b-aa89ed1b56d6 last_name: Fatichi citation: ama: Meili N, Acero JA, Peleg N, Manoli G, Burlando P, Fatichi S. Vegetation cover and plant-trait effects on outdoor thermal comfort in a tropical city. Building and Environment. 2021;195. doi:10.1016/j.buildenv.2021.107733 apa: Meili, N., Acero, J. A., Peleg, N., Manoli, G., Burlando, P., & Fatichi, S. (2021). Vegetation cover and plant-trait effects on outdoor thermal comfort in a tropical city. Building and Environment. Elsevier. https://doi.org/10.1016/j.buildenv.2021.107733 chicago: Meili, Naika, Juan Angel Acero, Nadav Peleg, Gabriele Manoli, Paolo Burlando, and Simone Fatichi. “Vegetation Cover and Plant-Trait Effects on Outdoor Thermal Comfort in a Tropical City.” Building and Environment. Elsevier, 2021. https://doi.org/10.1016/j.buildenv.2021.107733. ieee: N. Meili, J. A. Acero, N. Peleg, G. Manoli, P. Burlando, and S. Fatichi, “Vegetation cover and plant-trait effects on outdoor thermal comfort in a tropical city,” Building and Environment, vol. 195. Elsevier, 2021. ista: Meili N, Acero JA, Peleg N, Manoli G, Burlando P, Fatichi S. 2021. Vegetation cover and plant-trait effects on outdoor thermal comfort in a tropical city. Building and Environment. 195, 107733. mla: Meili, Naika, et al. “Vegetation Cover and Plant-Trait Effects on Outdoor Thermal Comfort in a Tropical City.” Building and Environment, vol. 195, 107733, Elsevier, 2021, doi:10.1016/j.buildenv.2021.107733. short: N. Meili, J.A. Acero, N. Peleg, G. Manoli, P. Burlando, S. Fatichi, Building and Environment 195 (2021). das_tickbox: '1' date_created: 2026-07-27T12:30:23Z date_published: 2021-05-01T00:00:00Z date_updated: 2026-07-30T09:12:50Z day: '01' ddc: - '550' doi: 10.1016/j.buildenv.2021.107733 extern: '1' has_accepted_license: '1' intvolume: ' 195' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1016/j.buildenv.2021.107733 month: '05' oa: 1 oa_version: Published Version publication: Building and Environment publication_identifier: issn: - 0360-1323 publication_status: published publisher: Elsevier quality_controlled: '1' scopus_import: '1' status: public title: Vegetation cover and plant-trait effects on outdoor thermal comfort in a tropical city tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 195 year: '2021' ... --- DOAJ_listed: '1' OA_place: publisher OA_type: gold PlanS_conform: '1' _id: '22448' abstract: - lang: eng text: Groundwater is a key water resource in semiarid and seasonally dry regions around the world, which is replenished by intermittent precipitation events and mediated by vegetation, soil, and regolith properties. Here, a climate reconstruction of 4500 years for the Jerusalem region was used to determine the relation between climate, vegetation, and groundwater recharge. Despite changes in air temperature and vegetation characteristics, simulated recharge remained linearly related to precipitation over the entire analyzed period, with drier decades having lower rates of recharge for a given annual precipitation due to soil memory effects. We show that in recent decades, the lack of changes in the precipitation–groundwater recharge relation results from the compensating responses of vegetation to increasing CO2, i.e., increased leaf area and reduced stomatal conductance. This multicentury relation is expected to be modified by climate change, with changes up to −20% in recharge for unchanged precipitation, potentially jeopardizing water resource availability. article_number: eabe6303 article_processing_charge: Yes article_type: original author: - first_name: Simone full_name: Fatichi, Simone id: cf8e546b-a9b0-11f0-a43b-aa89ed1b56d6 last_name: Fatichi - first_name: Nadav full_name: Peleg, Nadav last_name: Peleg - first_name: Theodoros full_name: Mastrotheodoros, Theodoros last_name: Mastrotheodoros - first_name: Christoforos full_name: Pappas, Christoforos last_name: Pappas - first_name: Gabriele full_name: Manoli, Gabriele last_name: Manoli citation: ama: Fatichi S, Peleg N, Mastrotheodoros T, Pappas C, Manoli G. An ecohydrological journey of 4500 years reveals a stable but threatened precipitation–groundwater recharge relation around Jerusalem. Science Advances. 2021;7(37). doi:10.1126/sciadv.abe6303 apa: Fatichi, S., Peleg, N., Mastrotheodoros, T., Pappas, C., & Manoli, G. (2021). An ecohydrological journey of 4500 years reveals a stable but threatened precipitation–groundwater recharge relation around Jerusalem. Science Advances. American Association for the Advancement of Science. https://doi.org/10.1126/sciadv.abe6303 chicago: Fatichi, Simone, Nadav Peleg, Theodoros Mastrotheodoros, Christoforos Pappas, and Gabriele Manoli. “An Ecohydrological Journey of 4500 Years Reveals a Stable but Threatened Precipitation–Groundwater Recharge Relation around Jerusalem.” Science Advances. American Association for the Advancement of Science, 2021. https://doi.org/10.1126/sciadv.abe6303. ieee: S. Fatichi, N. Peleg, T. Mastrotheodoros, C. Pappas, and G. Manoli, “An ecohydrological journey of 4500 years reveals a stable but threatened precipitation–groundwater recharge relation around Jerusalem,” Science Advances, vol. 7, no. 37. American Association for the Advancement of Science, 2021. ista: Fatichi S, Peleg N, Mastrotheodoros T, Pappas C, Manoli G. 2021. An ecohydrological journey of 4500 years reveals a stable but threatened precipitation–groundwater recharge relation around Jerusalem. Science Advances. 7(37), eabe6303. mla: Fatichi, Simone, et al. “An Ecohydrological Journey of 4500 Years Reveals a Stable but Threatened Precipitation–Groundwater Recharge Relation around Jerusalem.” Science Advances, vol. 7, no. 37, eabe6303, American Association for the Advancement of Science, 2021, doi:10.1126/sciadv.abe6303. short: S. Fatichi, N. Peleg, T. Mastrotheodoros, C. Pappas, G. Manoli, Science Advances 7 (2021). das_tickbox: '1' date_created: 2026-07-27T12:30:23Z date_published: 2021-09-01T00:00:00Z date_updated: 2026-07-30T09:24:02Z day: '01' ddc: - '550' doi: 10.1126/sciadv.abe6303 extern: '1' has_accepted_license: '1' intvolume: ' 7' issue: '37' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1126/sciadv.abe6303 month: '09' oa: 1 oa_version: Published Version publication: Science Advances publication_identifier: eissn: - 2375-2548 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: An ecohydrological journey of 4500 years reveals a stable but threatened precipitation–groundwater recharge relation around Jerusalem tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 7 year: '2021' ... --- OA_place: publisher OA_type: free access _id: '22452' abstract: - lang: eng text: 'Model fidelity and accuracy in process representations have been the crux of scientific hydrological modeling, creating a pressing need for a better linkage between the development of hydrological models and the growing number of data sources and measurement techniques. Improved representation of process dynamics in hydrological models can provide new insights into complex hydrological systems and point out less understood natural phenomena that need further investigation. This special issue includes contributions that offer potential solutions and strategies to improve and test the representation of hydrological processes. We have organized the special issue contributions into four topical categories: (a) Beyond streamflow, which looks into the power of complementary data sources in addition to traditionally used streamflow for process inference. (b) Challenge of subsurface hydrology, that reflects on lesser understood processes under the surface and their impact on the model structure. (c) Evaporation in hydrological modeling, linking ecological aspects to the hydrological functioning of the natural system. Finally, (d) top down vs. bottom up modeling approaches, relied upon for process representation analysis. The special issue and our reflection on the contributions present a snapshot of ongoing efforts for integrating new concepts, knowledge, and data in process representation in hydrological models.' article_number: e2021WR030661 article_processing_charge: No article_type: original author: - first_name: Björn full_name: Guse, Björn last_name: Guse - first_name: Simone full_name: Fatichi, Simone id: cf8e546b-a9b0-11f0-a43b-aa89ed1b56d6 last_name: Fatichi - first_name: Shervan full_name: Gharari, Shervan last_name: Gharari - first_name: Lieke A. full_name: Melsen, Lieke A. last_name: Melsen citation: ama: 'Guse B, Fatichi S, Gharari S, Melsen LA. Advancing process representation in hydrological models: Integrating new concepts, knowledge, and data. Water Resources Research. 2021;57(11). doi:10.1029/2021wr030661' apa: 'Guse, B., Fatichi, S., Gharari, S., & Melsen, L. A. (2021). Advancing process representation in hydrological models: Integrating new concepts, knowledge, and data. Water Resources Research. American Geophysical Union. https://doi.org/10.1029/2021wr030661' chicago: 'Guse, Björn, Simone Fatichi, Shervan Gharari, and Lieke A. Melsen. “Advancing Process Representation in Hydrological Models: Integrating New Concepts, Knowledge, and Data.” Water Resources Research. American Geophysical Union, 2021. https://doi.org/10.1029/2021wr030661.' ieee: 'B. Guse, S. Fatichi, S. Gharari, and L. A. Melsen, “Advancing process representation in hydrological models: Integrating new concepts, knowledge, and data,” Water Resources Research, vol. 57, no. 11. American Geophysical Union, 2021.' ista: 'Guse B, Fatichi S, Gharari S, Melsen LA. 2021. Advancing process representation in hydrological models: Integrating new concepts, knowledge, and data. Water Resources Research. 57(11), e2021WR030661.' mla: 'Guse, Björn, et al. “Advancing Process Representation in Hydrological Models: Integrating New Concepts, Knowledge, and Data.” Water Resources Research, vol. 57, no. 11, e2021WR030661, American Geophysical Union, 2021, doi:10.1029/2021wr030661.' short: B. Guse, S. Fatichi, S. Gharari, L.A. Melsen, Water Resources Research 57 (2021). das_tickbox: '1' date_created: 2026-07-27T12:30:23Z date_published: 2021-11-01T00:00:00Z date_updated: 2026-07-30T09:15:11Z day: '01' doi: 10.1029/2021wr030661 extern: '1' intvolume: ' 57' issue: '11' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1029/2021WR030661 month: '11' oa: 1 oa_version: Published Version publication: Water Resources Research publication_identifier: eissn: - 1944-7973 issn: - 0043-1397 publication_status: published publisher: American Geophysical Union quality_controlled: '1' scopus_import: '1' status: public title: 'Advancing process representation in hydrological models: Integrating new concepts, knowledge, and data' type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 57 year: '2021' ... --- _id: '10579' abstract: - lang: eng text: 'We consider a totally asymmetric simple exclusion process (TASEP) consisting of particles on a lattice that require binding by a "token" to move. Using a combination of theory and simulations, we address the following questions: (i) How token binding kinetics affects the current-density relation; (ii) How the current-density relation depends on the scarcity of tokens; (iii) How tokens propagate the effects of the locally-imposed disorder (such a slow site) over the entire lattice; (iv) How a shared pool of tokens couples concurrent TASEPs running on multiple lattices; (v) How our results translate to TASEPs with open boundaries that exchange particles with the reservoir. Since real particle motion (including in systems that inspired the standard TASEP model, e.g., protein synthesis or movement of molecular motors) is often catalyzed, regulated, actuated, or otherwise mediated, the token-driven TASEP dynamics analyzed in this paper should allow for a better understanding of real systems and enable a closer match between TASEP theory and experimental observations.' acknowledgement: B.K. thanks Stefano Elefante, Simon Rella, and Michal Hledík for their help with the usage of the cluster. B.K. additionally thanks Călin Guet and his group for help and advice. We thank M. Hennessey-Wesen for constructive comments on the manuscript. We thank Ankita Gupta (Indian Institute of Technology) for spotting a typographical error in Eq. (49) in the preprint version of this paper. article_number: '2112.13558' article_processing_charge: No arxiv: 1 author: - first_name: Bor full_name: Kavcic, Bor id: 350F91D2-F248-11E8-B48F-1D18A9856A87 last_name: Kavcic orcid: 0000-0001-6041-254X - first_name: Gašper full_name: Tkačik, Gašper id: 3D494DCA-F248-11E8-B48F-1D18A9856A87 last_name: Tkačik orcid: 0000-0002-6699-1455 citation: ama: Kavcic B, Tkačik G. Token-driven totally asymmetric simple exclusion process. arXiv. doi:10.48550/arXiv.2112.13558 apa: Kavcic, B., & Tkačik, G. (n.d.). Token-driven totally asymmetric simple exclusion process. arXiv. https://doi.org/10.48550/arXiv.2112.13558 chicago: Kavcic, Bor, and Gašper Tkačik. “Token-Driven Totally Asymmetric Simple Exclusion Process.” ArXiv, n.d. https://doi.org/10.48550/arXiv.2112.13558. ieee: B. Kavcic and G. Tkačik, “Token-driven totally asymmetric simple exclusion process,” arXiv. . ista: Kavcic B, Tkačik G. Token-driven totally asymmetric simple exclusion process. arXiv, 2112.13558. mla: Kavcic, Bor, and Gašper Tkačik. “Token-Driven Totally Asymmetric Simple Exclusion Process.” ArXiv, 2112.13558, doi:10.48550/arXiv.2112.13558. short: B. Kavcic, G. Tkačik, ArXiv (n.d.). corr_author: '1' date_created: 2021-12-28T06:52:09Z date_published: 2021-12-27T00:00:00Z date_updated: 2026-08-04T08:34:23Z day: '27' ddc: - '530' department: - _id: GaTk doi: 10.48550/arXiv.2112.13558 external_id: arxiv: - '2112.13558' has_accepted_license: '1' language: - iso: eng main_file_link: - open_access: '1' url: https://arxiv.org/abs/2112.13558 month: '12' oa: 1 oa_version: Preprint publication: arXiv publication_status: submitted related_material: record: - id: '19785' relation: later_version status: public status: public title: Token-driven totally asymmetric simple exclusion process tmp: image: /images/cc_by_nc_nd.png legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) short: CC BY-NC-ND (4.0) type: preprint user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2021' ... --- OA_place: repository OA_type: green _id: '22546' abstract: - lang: eng text: Increasing urban green spaces and canopy cover requires careful planning of irrigation strategies, especially in arid and semiarid areas. This study investigates how vegetation cover and irrigation affect the water balance and vegetation productivity of a small urban reserve in the Melbourne metropolitan area, Australia. Using a mechanistic ecohydrological model, a series of numerical experiments were carried out for the period 1999–2018, which included a prolonged drought. Results indicated that irrigation played an essential role in helping both trees and grass productivity by increasing soil moisture and vegetation water access during the drought. With 10% tree cover, grass benefitted more than trees by increasing irrigation, and trees coped well with drought even without additional water. However, trees strongly relied on irrigation to maintain productivity when tree cover increased, highlighting the need for a sustainable balance between increasing urban greening and water conservation. Differences in soil properties and rooting strategies were also found to strongly modify the need for irrigation and the competition for water. These results provide quantitative insights on how increasing tree cover and vegetation diversity may impact irrigation requirements, highlighting the key role of mechanistic numerical models to support urban planners in the evaluation and design of urban green spaces. article_number: '104198' article_processing_charge: No article_type: original author: - first_name: V. full_name: Marchionni, V. last_name: Marchionni - first_name: Simone full_name: Fatichi, Simone id: cf8e546b-a9b0-11f0-a43b-aa89ed1b56d6 last_name: Fatichi - first_name: N. full_name: Tapper, N. last_name: Tapper - first_name: J.P. full_name: Walker, J.P. last_name: Walker - first_name: G. full_name: Manoli, G. last_name: Manoli - first_name: E. full_name: Daly, E. last_name: Daly citation: ama: Marchionni V, Fatichi S, Tapper N, Walker JP, Manoli G, Daly E. Assessing vegetation response to irrigation strategies and soil properties in an urban reserve in southeast Australia. Landscape and Urban Planning. 2021;215. doi:10.1016/j.landurbplan.2021.104198 apa: Marchionni, V., Fatichi, S., Tapper, N., Walker, J. P., Manoli, G., & Daly, E. (2021). Assessing vegetation response to irrigation strategies and soil properties in an urban reserve in southeast Australia. Landscape and Urban Planning. Elsevier. https://doi.org/10.1016/j.landurbplan.2021.104198 chicago: Marchionni, V., Simone Fatichi, N. Tapper, J.P. Walker, G. Manoli, and E. Daly. “Assessing Vegetation Response to Irrigation Strategies and Soil Properties in an Urban Reserve in Southeast Australia.” Landscape and Urban Planning. Elsevier, 2021. https://doi.org/10.1016/j.landurbplan.2021.104198. ieee: V. Marchionni, S. Fatichi, N. Tapper, J. P. Walker, G. Manoli, and E. Daly, “Assessing vegetation response to irrigation strategies and soil properties in an urban reserve in southeast Australia,” Landscape and Urban Planning, vol. 215. Elsevier, 2021. ista: Marchionni V, Fatichi S, Tapper N, Walker JP, Manoli G, Daly E. 2021. Assessing vegetation response to irrigation strategies and soil properties in an urban reserve in southeast Australia. Landscape and Urban Planning. 215, 104198. mla: Marchionni, V., et al. “Assessing Vegetation Response to Irrigation Strategies and Soil Properties in an Urban Reserve in Southeast Australia.” Landscape and Urban Planning, vol. 215, 104198, Elsevier, 2021, doi:10.1016/j.landurbplan.2021.104198. short: V. Marchionni, S. Fatichi, N. Tapper, J.P. Walker, G. Manoli, E. Daly, Landscape and Urban Planning 215 (2021). das_tickbox: '1' date_created: 2026-07-27T12:30:24Z date_published: 2021-11-01T00:00:00Z date_updated: 2026-08-06T08:20:58Z day: '01' doi: 10.1016/j.landurbplan.2021.104198 extern: '1' intvolume: ' 215' keyword: - Urban green spaces - Remnant vegetation - Irrigation - Stormwater harvesting - Ecohydrological modeling language: - iso: eng main_file_link: - open_access: '1' url: https://discovery.ucl.ac.uk/id/eprint/10133304/1/REVISED_Manuscript_Marchionni.pdf month: '11' oa: 1 oa_version: Preprint publication: Landscape and Urban Planning publication_identifier: eissn: - 1872-6062 issn: - 0169-2046 publication_status: published publisher: Elsevier quality_controlled: '1' scopus_import: '1' status: public title: Assessing vegetation response to irrigation strategies and soil properties in an urban reserve in southeast Australia type: journal_article user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd volume: 215 year: '2021' ...