---
_id: '11453'
abstract:
- lang: eng
text: "Neuronal computations depend on synaptic connectivity and intrinsic electrophysiological
properties. Synaptic connectivity determines which inputs from presynaptic neurons
are integrated, while cellular properties determine how inputs are filtered over
time. Unlike their biological counterparts, most computational approaches to learning
in simulated neural networks are limited to changes in synaptic connectivity.
However, if intrinsic parameters change, neural computations are altered drastically.
Here, we include the parameters that determine the intrinsic properties,\r\ne.g.,
time constants and reset potential, into the learning paradigm. Using sparse feedback
signals that indicate target spike times, and gradient-based parameter updates,
we show that the intrinsic parameters can be learned along with the synaptic weights
to produce specific input-output functions. Specifically, we use a teacher-student
paradigm in which a randomly initialised leaky integrate-and-fire or resonate-and-fire
neuron must recover the parameters of a teacher neuron. We show that complex temporal
functions can be learned online and without backpropagation through time, relying
on event-based updates only. Our results are a step towards online learning of
neural computations from ungraded and unsigned sparse feedback signals with a
biologically inspired learning mechanism."
acknowledgement: We would like to thank Professor Dr. Henning Sprekeler for his valuable
suggestions and Dr. Andrew Saxe, Milan Klöwer and Anna Wallis for their constructive
feedback on the manuscript. Lukas Braun was supported by the Network of European
Neuroscience Schools through their NENS Exchange Grant program, by the European
Union through their European Community Action Scheme for the Mobility of University
Students, the Woodward Scholarship awarded by Wadham College, Oxford and the Medical
Research Council [MR/N013468/1]. Tim P. Vogels was supported by a Wellcome Trust
Senior Research Fellowship [214316/Z/18/Z].
alternative_title:
- Advances in Neural Information Processing Systems
article_processing_charge: No
author:
- first_name: Lukas
full_name: Braun, Lukas
last_name: Braun
- first_name: Tim P
full_name: Vogels, Tim P
id: CB6FF8D2-008F-11EA-8E08-2637E6697425
last_name: Vogels
orcid: 0000-0003-3295-6181
citation:
ama: 'Braun L, Vogels TP. Online learning of neural computations from sparse temporal
feedback. In: 35th Conference on Neural Information Processing Systems.
Vol 20. Neural Information Processing Systems Foundation; 2021:16437-16450.'
apa: 'Braun, L., & Vogels, T. P. (2021). Online learning of neural computations
from sparse temporal feedback. In 35th Conference on Neural Information Processing
Systems (Vol. 20, pp. 16437–16450). Virtual, Online: Neural Information Processing
Systems Foundation.'
chicago: Braun, Lukas, and Tim P Vogels. “Online Learning of Neural Computations
from Sparse Temporal Feedback.” In 35th Conference on Neural Information Processing
Systems, 20:16437–50. Neural Information Processing Systems Foundation, 2021.
ieee: L. Braun and T. P. Vogels, “Online learning of neural computations from sparse
temporal feedback,” in 35th Conference on Neural Information Processing Systems,
Virtual, Online, 2021, vol. 20, pp. 16437–16450.
ista: 'Braun L, Vogels TP. 2021. Online learning of neural computations from sparse
temporal feedback. 35th Conference on Neural Information Processing Systems. NeurIPS:
Neural Information Processing Systems, Advances in Neural Information Processing
Systems, vol. 20, 16437–16450.'
mla: Braun, Lukas, and Tim P. Vogels. “Online Learning of Neural Computations from
Sparse Temporal Feedback.” 35th Conference on Neural Information Processing
Systems, vol. 20, Neural Information Processing Systems Foundation, 2021,
pp. 16437–50.
short: L. Braun, T.P. Vogels, in:, 35th Conference on Neural Information Processing
Systems, Neural Information Processing Systems Foundation, 2021, pp. 16437–16450.
conference:
end_date: 2021-12-14
location: Virtual, Online
name: 'NeurIPS: Neural Information Processing Systems'
start_date: 2021-12-06
corr_author: '1'
das_tickbox: '1'
date_created: 2022-06-19T22:01:59Z
date_published: 2021-12-01T00:00:00Z
date_updated: 2026-07-08T05:45:00Z
day: '01'
ddc:
- '000'
- '570'
department:
- _id: TiVo
intvolume: ' 20'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://proceedings.neurips.cc/paper/2021/file/88e1ce84f9feef5a08d0df0334c53468-Paper.pdf
month: '12'
oa: 1
oa_version: Published Version
page: 16437-16450
project:
- _id: c084a126-5a5b-11eb-8a69-d75314a70a87
grant_number: 214316/Z/18/Z
name: "Whatâ\x80\x99s in a memory? Spatiotemporal dynamics in strongly coupled recurrent
neuronal networks."
publication: 35th Conference on Neural Information Processing Systems
publication_identifier:
isbn:
- '9781713845393'
issn:
- 1049-5258
publication_status: published
publisher: Neural Information Processing Systems Foundation
quality_controlled: '1'
scopus_import: '1'
status: public
title: Online learning of neural computations from sparse temporal feedback
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 20
year: '2021'
...
---
_id: '11452'
abstract:
- lang: eng
text: We study efficient distributed algorithms for the fundamental problem of principal
component analysis and leading eigenvector computation on the sphere, when the
data are randomly distributed among a set of computational nodes. We propose a
new quantized variant of Riemannian gradient descent to solve this problem, and
prove that the algorithm converges with high probability under a set of necessary
spherical-convexity properties. We give bounds on the number of bits transmitted
by the algorithm under common initialization schemes, and investigate the dependency
on the problem dimension in each case.
acknowledgement: We would like to thank the anonymous reviewers for helpful comments
and suggestions. We also thank Aurelien Lucchi and Antonio Orvieto for fruitful
discussions at an early stage of this work. FA is partially supported by the SNSF
under research project No. 192363 and conducted part of this work while at IST Austria
under the European Union’s Horizon 2020 research and innovation programme (grant
agreement No. 805223 ScaleML). PD partly conducted this work while at IST Austria
and was supported by the European Union’s Horizon 2020 programme under the Marie
Skłodowska-Curie grant agreement No. 754411.
alternative_title:
- Advances in Neural Information Processing Systems
article_processing_charge: No
arxiv: 1
author:
- first_name: Foivos
full_name: Alimisis, Foivos
last_name: Alimisis
- first_name: Peter
full_name: Davies, Peter
id: 11396234-BB50-11E9-B24C-90FCE5697425
last_name: Davies
orcid: 0000-0002-5646-9524
- first_name: Bart
full_name: Vandereycken, Bart
last_name: Vandereycken
- first_name: Dan-Adrian
full_name: Alistarh, Dan-Adrian
id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
last_name: Alistarh
orcid: 0000-0003-3650-940X
citation:
ama: 'Alimisis F, Davies P, Vandereycken B, Alistarh D-A. Distributed principal
component analysis with limited communication. In: 35th Conference on Neural
Information Processing Systems. Vol 4. Neural Information Processing Systems
Foundation; 2021:2823-2834.'
apa: 'Alimisis, F., Davies, P., Vandereycken, B., & Alistarh, D.-A. (2021).
Distributed principal component analysis with limited communication. In 35th
Conference on Neural Information Processing Systems (Vol. 4, pp. 2823–2834).
Virtual, Online: Neural Information Processing Systems Foundation.'
chicago: Alimisis, Foivos, Peter Davies, Bart Vandereycken, and Dan-Adrian Alistarh.
“Distributed Principal Component Analysis with Limited Communication.” In 35th
Conference on Neural Information Processing Systems, 4:2823–34. Neural Information
Processing Systems Foundation, 2021.
ieee: F. Alimisis, P. Davies, B. Vandereycken, and D.-A. Alistarh, “Distributed
principal component analysis with limited communication,” in 35th Conference
on Neural Information Processing Systems, Virtual, Online, 2021, vol. 4, pp.
2823–2834.
ista: 'Alimisis F, Davies P, Vandereycken B, Alistarh D-A. 2021. Distributed principal
component analysis with limited communication. 35th Conference on Neural Information
Processing Systems. NeurIPS: Neural Information Processing Systems, Advances in
Neural Information Processing Systems, vol. 4, 2823–2834.'
mla: Alimisis, Foivos, et al. “Distributed Principal Component Analysis with Limited
Communication.” 35th Conference on Neural Information Processing Systems,
vol. 4, Neural Information Processing Systems Foundation, 2021, pp. 2823–34.
short: F. Alimisis, P. Davies, B. Vandereycken, D.-A. Alistarh, in:, 35th Conference
on Neural Information Processing Systems, Neural Information Processing Systems
Foundation, 2021, pp. 2823–2834.
conference:
end_date: 2021-12-14
location: Virtual, Online
name: 'NeurIPS: Neural Information Processing Systems'
start_date: 2021-12-06
corr_author: '1'
das_tickbox: '1'
date_created: 2022-06-19T22:01:58Z
date_published: 2021-12-01T00:00:00Z
date_updated: 2026-07-08T05:44:33Z
day: '01'
ddc:
- '000'
department:
- _id: DaAl
ec_funded: 1
external_id:
arxiv:
- '2110.14391'
intvolume: ' 4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://proceedings.neurips.cc/paper/2021/file/1680e9fa7b4dd5d62ece800239bb53bd-Paper.pdf
month: '12'
oa: 1
oa_version: Published Version
page: 2823-2834
project:
- _id: 268A44D6-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '805223'
name: Elastic Coordination for Scalable Machine Learning
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: 35th Conference on Neural Information Processing Systems
publication_identifier:
isbn:
- '9781713845393'
issn:
- 1049-5258
publication_status: published
publisher: Neural Information Processing Systems Foundation
quality_controlled: '1'
scopus_import: '1'
status: public
title: Distributed principal component analysis with limited communication
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 4
year: '2021'
...
---
OA_place: repository
OA_type: green
_id: '22156'
abstract:
- lang: eng
text: Extending a recent breakthrough of Shitov, we prove that the chromatic number
of the tensor product of two graphs can be a constant factor smaller than the
minimum chromatic number of the two graphs. More precisely, we prove that there
exists an absolute constant δ>0 such that for all c sufficiently large, there
exist graphs G and H with chromatic number at least (1+δ)c for which χ(G×H)≤c.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Xiaoyu
full_name: He, Xiaoyu
last_name: He
- first_name: Yuval
full_name: Wigderson, Yuval
id: 2d0023a0-1567-11f0-833d-d5c1e476d4b5
last_name: Wigderson
citation:
ama: He X, Wigderson Y. Hedetniemi’s conjecture is asymptotically false. Journal
of Combinatorial Theory, Series B. 2021;146:485-494. doi:10.1016/j.jctb.2020.03.003
apa: He, X., & Wigderson, Y. (2021). Hedetniemi’s conjecture is asymptotically
false. Journal of Combinatorial Theory, Series B. Elsevier. https://doi.org/10.1016/j.jctb.2020.03.003
chicago: He, Xiaoyu, and Yuval Wigderson. “Hedetniemi’s Conjecture Is Asymptotically
False.” Journal of Combinatorial Theory, Series B. Elsevier, 2021. https://doi.org/10.1016/j.jctb.2020.03.003.
ieee: X. He and Y. Wigderson, “Hedetniemi’s conjecture is asymptotically false,”
Journal of Combinatorial Theory, Series B, vol. 146. Elsevier, pp. 485–494,
2021.
ista: He X, Wigderson Y. 2021. Hedetniemi’s conjecture is asymptotically false.
Journal of Combinatorial Theory, Series B. 146, 485–494.
mla: He, Xiaoyu, and Yuval Wigderson. “Hedetniemi’s Conjecture Is Asymptotically
False.” Journal of Combinatorial Theory, Series B, vol. 146, Elsevier,
2021, pp. 485–94, doi:10.1016/j.jctb.2020.03.003.
short: X. He, Y. Wigderson, Journal of Combinatorial Theory, Series B 146 (2021)
485–494.
date_created: 2026-06-29T10:50:09Z
date_published: 2021-01-01T00:00:00Z
date_updated: 2026-07-08T07:43:57Z
day: '01'
doi: 10.1016/j.jctb.2020.03.003
extern: '1'
external_id:
arxiv:
- '1906.06783'
fulldoi: https://doi.org/10.1016/j.jctb.2020.03.003
intvolume: ' 146'
keyword:
- Graph coloring
- Hedetniemi's conjecture
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.1906.06783
month: '01'
oa: 1
oa_version: Preprint
page: 485-494
publication: Journal of Combinatorial Theory, Series B
publication_identifier:
issn:
- 0095-8956
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Hedetniemi's conjecture is asymptotically false
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 146
year: '2021'
...
---
_id: '9331'
abstract:
- lang: eng
text: 'Quantum entanglement has been generated and verified in cold-atom experiments
and used to make atom-interferometric measurements below the shot-noise limit.
However, current state-of-the-art cold-atom devices exploit separable (i.e., unentangled)
atomic states. This perspective piece asks the question: can entanglement usefully
improve cold-atom sensors, in the sense that it gives new sensing capabilities
unachievable with current state-of-the-art devices? We briefly review the state-of-the-art
in precision cold-atom sensing, focusing on clocks and inertial sensors, identifying
the potential benefits entanglement could bring to these devices, and the challenges
that need to be overcome to realize these benefits. We survey demonstrated methods
of generating metrologically useful entanglement in cold-atom systems, note their
relative strengths and weaknesses, and assess their prospects for near-to-medium
term quantum-enhanced cold-atom sensing.'
acknowledgement: We acknowledge fruitful discussions with John Close, Chris Freier,
Kyle Hardman, Joseph Hope, and Paul Wigley, and insightful suggestions made by Franck
Pereira dos Santos on behalf of the Atom Interferometry and Inertial Sensors team
at SYRTE. S.S.S. was supported by an Australian Research Council Discovery Early
Career Researcher Award (DECRA), Project No. DE200100495. O.H. was supported by
IST Austria.
article_number: '140501'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Stuart S.
full_name: Szigeti, Stuart S.
last_name: Szigeti
- first_name: Onur
full_name: Hosten, Onur
id: 4C02D85E-F248-11E8-B48F-1D18A9856A87
last_name: Hosten
orcid: 0000-0002-2031-204X
- first_name: Simon A.
full_name: Haine, Simon A.
last_name: Haine
citation:
ama: 'Szigeti SS, Hosten O, Haine SA. Improving cold-atom sensors with quantum entanglement:
Prospects and challenges. Applied Physics Letters. 2021;118(14). doi:10.1063/5.0050235'
apa: 'Szigeti, S. S., Hosten, O., & Haine, S. A. (2021). Improving cold-atom
sensors with quantum entanglement: Prospects and challenges. Applied Physics
Letters. AIP Publishing. https://doi.org/10.1063/5.0050235'
chicago: 'Szigeti, Stuart S., Onur Hosten, and Simon A. Haine. “Improving Cold-Atom
Sensors with Quantum Entanglement: Prospects and Challenges.” Applied Physics
Letters. AIP Publishing, 2021. https://doi.org/10.1063/5.0050235.'
ieee: 'S. S. Szigeti, O. Hosten, and S. A. Haine, “Improving cold-atom sensors with
quantum entanglement: Prospects and challenges,” Applied Physics Letters,
vol. 118, no. 14. AIP Publishing, 2021.'
ista: 'Szigeti SS, Hosten O, Haine SA. 2021. Improving cold-atom sensors with quantum
entanglement: Prospects and challenges. Applied Physics Letters. 118(14), 140501.'
mla: 'Szigeti, Stuart S., et al. “Improving Cold-Atom Sensors with Quantum Entanglement:
Prospects and Challenges.” Applied Physics Letters, vol. 118, no. 14, 140501,
AIP Publishing, 2021, doi:10.1063/5.0050235.'
short: S.S. Szigeti, O. Hosten, S.A. Haine, Applied Physics Letters 118 (2021).
corr_author: '1'
das_tickbox: '1'
dataavailabilitystatement: The data that support the findings of this study are available
from the corresponding author upon reasonable request.
date_created: 2021-04-18T22:01:40Z
date_published: 2021-04-07T00:00:00Z
date_updated: 2026-07-08T08:53:45Z
day: '07'
department:
- _id: OnHo
doi: 10.1063/5.0050235
external_id:
arxiv:
- '2010.09168'
isi:
- '000637702100001'
fulldoi: https://doi.org/10.1063/5.0050235
intvolume: ' 118'
isi: 1
issue: '14'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/2010.09168
month: '04'
oa: 1
oa_version: Preprint
publication: Applied Physics Letters
publication_identifier:
issn:
- 0003-6951
publication_status: published
publisher: AIP Publishing
quality_controlled: '1'
researchdata_availability: upon request
scopus_import: '1'
status: public
supplementarymaterial: no
title: 'Improving cold-atom sensors with quantum entanglement: Prospects and challenges'
type: journal_article
user_id: 68b8ca59-c5b3-11ee-8790-cd641c68093d
volume: 118
year: '2021'
...
---
OA_place: repository
OA_type: green
_id: '22161'
abstract:
- lang: eng
text: "Recently, Souza introduced blowup Ramsey numbers as a gener-\r\nalization
of bipartite Ramsey numbers. For graphs G and H, say\r\nG r\r\n−→ H if every r-edge-coloring
of G contains a monochromatic\r\ncopy of H. Let H[t] denote the t-blowup of H.
Then the blowup\r\nRamsey number of G, H, r, and t is defined as the minimum n\r\nsuch
that G[n] r\r\n−→ H[t]. Souza proved upper and lower bounds on\r\nn that are exponential
in t, and conjectured that the exponential\r\nconstant does not depend on G. We
prove that the dependence on\r\nG in the exponential constant is indeed unnecessary,
but conjecture\r\nthat some dependence on G is unavoidable.\r\nAn important step
in both Souza’s proof and ours is a theorem of\r\nNikiforov, which says that if
a graph contains a constant fraction\r\nof the possible copies of H, then it contains
a blowup of H of\r\nlogarithmic size. We also provide a new proof of this theorem
with\r\na better quantitative dependence."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Jacob
full_name: Fox, Jacob
last_name: Fox
- first_name: Sammy
full_name: Luo, Sammy
last_name: Luo
- first_name: Yuval
full_name: Wigderson, Yuval
id: 2d0023a0-1567-11f0-833d-d5c1e476d4b5
last_name: Wigderson
citation:
ama: Fox J, Luo S, Wigderson Y. Extremal and Ramsey results on graph blowups. Journal
of Combinatorics. 2021;12(1):1-15. doi:10.4310/joc.2021.v12.n1.a1
apa: Fox, J., Luo, S., & Wigderson, Y. (2021). Extremal and Ramsey results on
graph blowups. Journal of Combinatorics. International Press of Boston.
https://doi.org/10.4310/joc.2021.v12.n1.a1
chicago: Fox, Jacob, Sammy Luo, and Yuval Wigderson. “Extremal and Ramsey Results
on Graph Blowups.” Journal of Combinatorics. International Press of Boston,
2021. https://doi.org/10.4310/joc.2021.v12.n1.a1.
ieee: J. Fox, S. Luo, and Y. Wigderson, “Extremal and Ramsey results on graph blowups,”
Journal of Combinatorics, vol. 12, no. 1. International Press of Boston,
pp. 1–15, 2021.
ista: Fox J, Luo S, Wigderson Y. 2021. Extremal and Ramsey results on graph blowups.
Journal of Combinatorics. 12(1), 1–15.
mla: Fox, Jacob, et al. “Extremal and Ramsey Results on Graph Blowups.” Journal
of Combinatorics, vol. 12, no. 1, International Press of Boston, 2021, pp.
1–15, doi:10.4310/joc.2021.v12.n1.a1.
short: J. Fox, S. Luo, Y. Wigderson, Journal of Combinatorics 12 (2021) 1–15.
date_created: 2026-06-29T10:52:13Z
date_published: 2021-01-01T00:00:00Z
date_updated: 2026-07-08T10:41:31Z
day: '01'
doi: 10.4310/joc.2021.v12.n1.a1
extern: '1'
external_id:
arxiv:
- '1912.08328'
fulldoi: https://doi.org/10.4310/joc.2021.v12.n1.a1
intvolume: ' 12'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.1912.08328
mathsc:
- 05C35
- 05C55
month: '01'
oa: 1
oa_version: Preprint
page: 1-15
publication: Journal of Combinatorics
publication_identifier:
eissn:
- 2150-959X
issn:
- 2156-3527
publication_status: published
publisher: International Press of Boston
quality_controlled: '1'
scopus_import: '1'
status: public
title: Extremal and Ramsey results on graph blowups
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2021'
...
---
_id: '17132'
abstract:
- lang: eng
text: Extracellular recording is an accessible technique used in animals
and humans to study the brain physiology and pathology. As the number of recording
channels and their density grows it is natural to ask how much improvement the
additional channels bring in and how we can optimally use the new capabilities
for monitoring the brain. Here we show that for any given distribution of electrodes
we can establish exactly what information about current sources in the brain can
be recovered and what information is strictly unobservable. We demonstrate this
in the general setting of previously proposed kernel Current Source Density method
and illustrate it with simplified examples as well as using evoked potentials
from the barrel cortex obtained with a Neuropixels probe and with compatible model
data. We show that with conceptual separation of the estimation space from experimental
setup one can recover sources not accessible to standard methods.
article_number: e1008615
article_processing_charge: No
article_type: original
author:
- first_name: Chaitanya
full_name: Chintaluri, Chaitanya
id: BA06AFEE-A4BA-11EA-AE5C-14673DDC885E
last_name: Chintaluri
orcid: 0000-0003-4252-1608
- first_name: Marta
full_name: Bejtka, Marta
last_name: Bejtka
- first_name: Władysław
full_name: Średniawa, Władysław
last_name: Średniawa
- first_name: Michał
full_name: Czerwiński, Michał
last_name: Czerwiński
- first_name: Jakub M.
full_name: Dzik, Jakub M.
last_name: Dzik
- first_name: Joanna
full_name: Jędrzejewska-Szmek, Joanna
last_name: Jędrzejewska-Szmek
- first_name: Kacper
full_name: Kondrakiewicz, Kacper
last_name: Kondrakiewicz
- first_name: Ewa
full_name: Kublik, Ewa
last_name: Kublik
- first_name: Daniel K.
full_name: Wójcik, Daniel K.
last_name: Wójcik
citation:
ama: Chintaluri C, Bejtka M, Średniawa W, et al. What we can and what we cannot
see with extracellular multielectrodes. PLOS Computational Biology. 2021;17(5).
doi:10.1371/journal.pcbi.1008615
apa: Chintaluri, C., Bejtka, M., Średniawa, W., Czerwiński, M., Dzik, J. M., Jędrzejewska-Szmek,
J., … Wójcik, D. K. (2021). What we can and what we cannot see with extracellular
multielectrodes. PLOS Computational Biology. Public Library of Science.
https://doi.org/10.1371/journal.pcbi.1008615
chicago: Chintaluri, Chaitanya, Marta Bejtka, Władysław Średniawa, Michał Czerwiński,
Jakub M. Dzik, Joanna Jędrzejewska-Szmek, Kacper Kondrakiewicz, Ewa Kublik, and
Daniel K. Wójcik. “What We Can and What We Cannot See with Extracellular Multielectrodes.”
PLOS Computational Biology. Public Library of Science, 2021. https://doi.org/10.1371/journal.pcbi.1008615.
ieee: C. Chintaluri et al., “What we can and what we cannot see with extracellular
multielectrodes,” PLOS Computational Biology, vol. 17, no. 5. Public Library
of Science, 2021.
ista: Chintaluri C, Bejtka M, Średniawa W, Czerwiński M, Dzik JM, Jędrzejewska-Szmek
J, Kondrakiewicz K, Kublik E, Wójcik DK. 2021. What we can and what we cannot
see with extracellular multielectrodes. PLOS Computational Biology. 17(5), e1008615.
mla: Chintaluri, Chaitanya, et al. “What We Can and What We Cannot See with Extracellular
Multielectrodes.” PLOS Computational Biology, vol. 17, no. 5, e1008615,
Public Library of Science, 2021, doi:10.1371/journal.pcbi.1008615.
short: C. Chintaluri, M. Bejtka, W. Średniawa, M. Czerwiński, J.M. Dzik, J. Jędrzejewska-Szmek,
K. Kondrakiewicz, E. Kublik, D.K. Wójcik, PLOS Computational Biology 17 (2021).
das_tickbox: '1'
date_created: 2024-06-11T14:43:37Z
date_published: 2021-05-14T00:00:00Z
date_updated: 2026-07-13T12:31:04Z
day: '14'
doi: 10.1371/journal.pcbi.1008615
extern: '1'
fulldoi: https://doi.org/10.1371/journal.pcbi.1008615
has_accepted_license: '1'
intvolume: ' 17'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1371/journal.pcbi.1008615
month: '05'
oa: 1
oa_version: Published Version
publication: PLOS Computational Biology
publication_identifier:
issn:
- 1553-7358
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
status: public
title: What we can and what we cannot see with extracellular multielectrodes
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2021'
...
---
OA_place: repository
OA_type: green
_id: '22169'
abstract:
- lang: eng
text: A recent breakthrough of Conlon and Ferber yielded an exponential improvement
on the lower bounds for multicolor diagonal Ramsey numbers. In this note, we modify
their construction and obtain improved bounds for more than three colors.
article_processing_charge: No
article_type: original
author:
- first_name: Yuval
full_name: Wigderson, Yuval
id: 2d0023a0-1567-11f0-833d-d5c1e476d4b5
last_name: Wigderson
citation:
ama: Wigderson Y. An improved lower bound on multicolor Ramsey numbers. Proceedings
of the American Mathematical Society. 2021;149(6):2371-2374. doi:10.1090/proc/15447
apa: Wigderson, Y. (2021). An improved lower bound on multicolor Ramsey numbers.
Proceedings of the American Mathematical Society. American Mathematical
Society. https://doi.org/10.1090/proc/15447
chicago: Wigderson, Yuval. “An Improved Lower Bound on Multicolor Ramsey Numbers.”
Proceedings of the American Mathematical Society. American Mathematical
Society, 2021. https://doi.org/10.1090/proc/15447.
ieee: Y. Wigderson, “An improved lower bound on multicolor Ramsey numbers,” Proceedings
of the American Mathematical Society, vol. 149, no. 6. American Mathematical
Society, pp. 2371–2374, 2021.
ista: Wigderson Y. 2021. An improved lower bound on multicolor Ramsey numbers. Proceedings
of the American Mathematical Society. 149(6), 2371–2374.
mla: Wigderson, Yuval. “An Improved Lower Bound on Multicolor Ramsey Numbers.” Proceedings
of the American Mathematical Society, vol. 149, no. 6, American Mathematical
Society, 2021, pp. 2371–74, doi:10.1090/proc/15447.
short: Y. Wigderson, Proceedings of the American Mathematical Society 149 (2021)
2371–2374.
date_created: 2026-06-29T10:55:23Z
date_published: 2021-06-01T00:00:00Z
date_updated: 2026-07-14T08:42:59Z
day: '01'
doi: 10.1090/proc/15447
extern: '1'
external_id:
unknown:
- '2009.12020'
fulldoi: https://doi.org/10.1090/proc/15447
intvolume: ' 149'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2009.12020
month: '06'
oa: 1
oa_version: Preprint
page: 2371-2374
publication: Proceedings of the American Mathematical Society
publication_identifier:
eissn:
- 1088-6826
issn:
- 0002-9939
publication_status: published
publisher: American Mathematical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: An improved lower bound on multicolor Ramsey numbers
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 149
year: '2021'
...
---
OA_place: repository
OA_type: green
_id: '22175'
abstract:
- lang: eng
text: We show how a number of well-known uncertainty principles for the Fourier
transform, such as the Heisenberg uncertainty principle, the Donoho–Stark uncertainty
principle, and Meshulam’s nonabelian uncertainty principle, have little to do
with the structure of the Fourier transform itself. Rather, all of these results
follow from very weak properties of the Fourier transform (shared by numerous
linear operators), namely that it is bounded as an operator L1 → L∞, and that
it is unitary. Using a single, simple proof template, and only these (or weaker)
properties, we obtain some new proofs and many generalizations of these basic
uncertainty principles, to new operators and to new settings, in a completely
unified way. Together with our general overview, this paper can also serve as
a survey of the many facets of the phenomena known as uncertainty principles.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Avi
full_name: Wigderson, Avi
last_name: Wigderson
- first_name: Yuval
full_name: Wigderson, Yuval
id: 2d0023a0-1567-11f0-833d-d5c1e476d4b5
last_name: Wigderson
citation:
ama: 'Wigderson A, Wigderson Y. The uncertainty principle: Variations on a theme.
Bulletin of the American Mathematical Society. 2021;58(2):225-261. doi:10.1090/bull/1715'
apa: 'Wigderson, A., & Wigderson, Y. (2021). The uncertainty principle: Variations
on a theme. Bulletin of the American Mathematical Society. American Mathematical
Society. https://doi.org/10.1090/bull/1715'
chicago: 'Wigderson, Avi, and Yuval Wigderson. “The Uncertainty Principle: Variations
on a Theme.” Bulletin of the American Mathematical Society. American Mathematical
Society, 2021. https://doi.org/10.1090/bull/1715.'
ieee: 'A. Wigderson and Y. Wigderson, “The uncertainty principle: Variations on
a theme,” Bulletin of the American Mathematical Society, vol. 58, no. 2.
American Mathematical Society, pp. 225–261, 2021.'
ista: 'Wigderson A, Wigderson Y. 2021. The uncertainty principle: Variations on
a theme. Bulletin of the American Mathematical Society. 58(2), 225–261.'
mla: 'Wigderson, Avi, and Yuval Wigderson. “The Uncertainty Principle: Variations
on a Theme.” Bulletin of the American Mathematical Society, vol. 58, no.
2, American Mathematical Society, 2021, pp. 225–61, doi:10.1090/bull/1715.'
short: A. Wigderson, Y. Wigderson, Bulletin of the American Mathematical Society
58 (2021) 225–261.
date_created: 2026-06-29T10:57:49Z
date_published: 2021-01-04T00:00:00Z
date_updated: 2026-07-14T09:02:39Z
day: '04'
doi: 10.1090/bull/1715
extern: '1'
external_id:
arxiv:
- '2006.11206'
fulldoi: https://doi.org/10.1090/bull/1715
intvolume: ' 58'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2006.11206
mathsc:
- 81S07
- 43A25
- 20C15
- 94A12
month: '01'
oa: 1
oa_version: Preprint
page: 225-261
publication: Bulletin of the American Mathematical Society
publication_identifier:
eissn:
- 1088-9485
issn:
- 0273-0979
publication_status: published
publisher: American Mathematical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The uncertainty principle: Variations on a theme'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 58
year: '2021'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '22207'
abstract:
- lang: eng
text: Phase separation is a ubiquitous process and finds applications in a variety
of biological, organic, and inorganic systems. Nature has evolved the ability
to control phase separation to both regulate cellular processes and make composite
materials with outstanding mechanical and optical properties. Striking examples
of the latter are the vibrant blue and green feathers of many bird species, which
are thought to result from an exquisite control of the size and spatial correlations
of their phase-separated microstructures. By contrast, it is much harder for material
scientists to arrest and control phase separation in synthetic materials with
such a high level of precision at these length scales. In this Perspective, we
briefly review some established methods to control liquid–liquid phase separation
processes and then highlight the emergence of a promising arrest method based
on phase separation in an elastic polymer network. Finally, we discuss upcoming
challenges and opportunities for fabricating microstructured materials via mechanically
controlled phase separation.
article_processing_charge: No
article_type: original
author:
- first_name: Carla
full_name: Fernández-Rico, Carla
id: 492def71-6250-11f0-b278-d41dbd241b62
last_name: Fernández-Rico
- first_name: Tianqi
full_name: Sai, Tianqi
last_name: Sai
- first_name: Alba
full_name: Sicher, Alba
last_name: Sicher
- first_name: Robert W.
full_name: Style, Robert W.
last_name: Style
- first_name: Eric R.
full_name: Dufresne, Eric R.
last_name: Dufresne
citation:
ama: Fernández-Rico C, Sai T, Sicher A, Style RW, Dufresne ER. Putting the squeeze
on phase separation. JACS Au. 2021;2(1):66-73. doi:10.1021/jacsau.1c00443
apa: Fernández-Rico, C., Sai, T., Sicher, A., Style, R. W., & Dufresne, E. R.
(2021). Putting the squeeze on phase separation. JACS Au. American Chemical
Society. https://doi.org/10.1021/jacsau.1c00443
chicago: Fernández-Rico, Carla, Tianqi Sai, Alba Sicher, Robert W. Style, and Eric
R. Dufresne. “Putting the Squeeze on Phase Separation.” JACS Au. American
Chemical Society, 2021. https://doi.org/10.1021/jacsau.1c00443.
ieee: C. Fernández-Rico, T. Sai, A. Sicher, R. W. Style, and E. R. Dufresne, “Putting
the squeeze on phase separation,” JACS Au, vol. 2, no. 1. American Chemical
Society, pp. 66–73, 2021.
ista: Fernández-Rico C, Sai T, Sicher A, Style RW, Dufresne ER. 2021. Putting the
squeeze on phase separation. JACS Au. 2(1), 66–73.
mla: Fernández-Rico, Carla, et al. “Putting the Squeeze on Phase Separation.” JACS
Au, vol. 2, no. 1, American Chemical Society, 2021, pp. 66–73, doi:10.1021/jacsau.1c00443.
short: C. Fernández-Rico, T. Sai, A. Sicher, R.W. Style, E.R. Dufresne, JACS Au
2 (2021) 66–73.
date_created: 2026-06-30T06:30:18Z
date_published: 2021-12-10T00:00:00Z
date_updated: 2026-07-15T05:55:35Z
day: '10'
ddc:
- '540'
doi: 10.1021/jacsau.1c00443
extern: '1'
external_id:
pmid:
- '35098222'
fulldoi: https://doi.org/10.1021/jacsau.1c00443
has_accepted_license: '1'
intvolume: ' 2'
issue: '1'
keyword:
- phase separation
- arrest
- bird feathers
- elasticity
- polymer networks
- microstructured materials
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1021/jacsau.1c00443
month: '12'
oa: 1
oa_version: Published Version
page: 66-73
pmid: 1
publication: JACS Au
publication_identifier:
eissn:
- 2691-3704
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Putting the squeeze on phase separation
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2
year: '2021'
...
---
OA_place: publisher
OA_type: hybrid
_id: '22211'
abstract:
- lang: eng
text: Hierarchically self-assembled materials—structures with order at multiple
length scales—can be found everywhere. Examples range from collagen structures
in human bones to engineered photonic materials. These structures usually assemble
from monodisperse microscopic building blocks that interact via complex directional
interactions. In this work, we show that hierarchical materials can, in fact,
also be assembled from polydisperse building blocks and by entropic interactions
alone. Our simple yet powerful assembly mechanism opens up avenues toward rationally
exploiting the often undesired polydispersity of colloidal building blocks for
programming entropy-driven self-assembly of hierarchical materials.
article_number: e2107241118
article_processing_charge: No
article_type: original
author:
- first_name: Carla
full_name: Fernández-Rico, Carla
id: 492def71-6250-11f0-b278-d41dbd241b62
last_name: Fernández-Rico
- first_name: Roel P. A.
full_name: Dullens, Roel P. A.
last_name: Dullens
citation:
ama: Fernández-Rico C, Dullens RPA. Hierarchical self-assembly of polydisperse colloidal
bananas into a two-dimensional vortex phase. Proceedings of the National Academy
of Sciences. 2021;118(33). doi:10.1073/pnas.2107241118
apa: Fernández-Rico, C., & Dullens, R. P. A. (2021). Hierarchical self-assembly
of polydisperse colloidal bananas into a two-dimensional vortex phase. Proceedings
of the National Academy of Sciences. National Academy of Sciences. https://doi.org/10.1073/pnas.2107241118
chicago: Fernández-Rico, Carla, and Roel P. A. Dullens. “Hierarchical Self-Assembly
of Polydisperse Colloidal Bananas into a Two-Dimensional Vortex Phase.” Proceedings
of the National Academy of Sciences. National Academy of Sciences, 2021. https://doi.org/10.1073/pnas.2107241118.
ieee: C. Fernández-Rico and R. P. A. Dullens, “Hierarchical self-assembly of polydisperse
colloidal bananas into a two-dimensional vortex phase,” Proceedings of the
National Academy of Sciences, vol. 118, no. 33. National Academy of Sciences,
2021.
ista: Fernández-Rico C, Dullens RPA. 2021. Hierarchical self-assembly of polydisperse
colloidal bananas into a two-dimensional vortex phase. Proceedings of the National
Academy of Sciences. 118(33), e2107241118.
mla: Fernández-Rico, Carla, and Roel P. A. Dullens. “Hierarchical Self-Assembly
of Polydisperse Colloidal Bananas into a Two-Dimensional Vortex Phase.” Proceedings
of the National Academy of Sciences, vol. 118, no. 33, e2107241118, National
Academy of Sciences, 2021, doi:10.1073/pnas.2107241118.
short: C. Fernández-Rico, R.P.A. Dullens, Proceedings of the National Academy of
Sciences 118 (2021).
date_created: 2026-06-30T06:31:50Z
date_published: 2021-08-13T00:00:00Z
date_updated: 2026-07-15T07:02:38Z
day: '13'
ddc:
- '540'
doi: 10.1073/pnas.2107241118
extern: '1'
external_id:
pmid:
- '34389681'
fulldoi: https://doi.org/10.1073/pnas.2107241118
has_accepted_license: '1'
intvolume: ' 118'
issue: '33'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1073/pnas.2107241118
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
publication: Proceedings of the National Academy of Sciences
publication_identifier:
eissn:
- 1091-6490
issn:
- 0027-8424
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Hierarchical self-assembly of polydisperse colloidal bananas into a two-dimensional
vortex phase
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 118
year: '2021'
...
---
OA_place: publisher
OA_type: hybrid
_id: '22217'
abstract:
- lang: eng
text: Surface roughness plays an important role in determining the mechanical properties,
wettability, and self-assembly in colloidal systems. In this work, we develop
a simple and fast method to produce rough colloidal SU-8 rods, bananas, and spheres,
via the nanoprecipitation of SU-8 in water. During this process, SU-8 nanospheres
are absorbed onto the surface of the colloidal SU-8 particles and then cross-linked
using UV-light. The size of the spherical asperities and the asperity density
are controlled by the concentration of SU-8 used during the nanoprecipitation
reaction. Fluorescent labeling of the rough SU-8 colloidal particles allows for
their confocal imaging, which demonstrates their stability at high packing fractions.
With these newly developed rough particles, we provide a colloidal model system
that allows for studies addressing the impact of surface roughness on materials
composed of anisotropic particles.
article_processing_charge: No
article_type: original
author:
- first_name: Carla
full_name: Fernández-Rico, Carla
id: 492def71-6250-11f0-b278-d41dbd241b62
last_name: Fernández-Rico
- first_name: Jeffrey S.
full_name: Urbach, Jeffrey S.
last_name: Urbach
- first_name: Roel P. A.
full_name: Dullens, Roel P. A.
last_name: Dullens
citation:
ama: Fernández-Rico C, Urbach JS, Dullens RPA. Synthesis of rough colloidal SU-8
rods and bananas via nanoprecipitation. Langmuir. 2021;37(9):2900-2906.
doi:10.1021/acs.langmuir.0c03361
apa: Fernández-Rico, C., Urbach, J. S., & Dullens, R. P. A. (2021). Synthesis
of rough colloidal SU-8 rods and bananas via nanoprecipitation. Langmuir.
American Chemical Society. https://doi.org/10.1021/acs.langmuir.0c03361
chicago: Fernández-Rico, Carla, Jeffrey S. Urbach, and Roel P. A. Dullens. “Synthesis
of Rough Colloidal SU-8 Rods and Bananas via Nanoprecipitation.” Langmuir.
American Chemical Society, 2021. https://doi.org/10.1021/acs.langmuir.0c03361.
ieee: C. Fernández-Rico, J. S. Urbach, and R. P. A. Dullens, “Synthesis of rough
colloidal SU-8 rods and bananas via nanoprecipitation,” Langmuir, vol.
37, no. 9. American Chemical Society, pp. 2900–2906, 2021.
ista: Fernández-Rico C, Urbach JS, Dullens RPA. 2021. Synthesis of rough colloidal
SU-8 rods and bananas via nanoprecipitation. Langmuir. 37(9), 2900–2906.
mla: Fernández-Rico, Carla, et al. “Synthesis of Rough Colloidal SU-8 Rods and Bananas
via Nanoprecipitation.” Langmuir, vol. 37, no. 9, American Chemical Society,
2021, pp. 2900–06, doi:10.1021/acs.langmuir.0c03361.
short: C. Fernández-Rico, J.S. Urbach, R.P.A. Dullens, Langmuir 37 (2021) 2900–2906.
date_created: 2026-06-30T06:36:01Z
date_published: 2021-02-26T00:00:00Z
date_updated: 2026-07-15T07:48:42Z
day: '26'
ddc:
- '540'
doi: 10.1021/acs.langmuir.0c03361
extern: '1'
external_id:
pmid:
- '33635671'
fulldoi: https://doi.org/10.1021/acs.langmuir.0c03361
has_accepted_license: '1'
intvolume: ' 37'
issue: '9'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1021/acs.langmuir.0c03361
month: '02'
oa: 1
oa_version: Published Version
page: 2900-2906
pmid: 1
publication: Langmuir
publication_identifier:
eissn:
- 1520-5827
issn:
- 0743-7463
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Synthesis of rough colloidal SU-8 rods and bananas via nanoprecipitation
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 37
year: '2021'
...
---
OA_place: publisher
OA_type: free access
_id: '9168'
abstract:
- lang: eng
text: Interspecific crossing experiments have shown that sex chromosomes play a
major role in reproductive isolation between many pairs of species. However, their
ability to act as reproductive barriers, which hamper interspecific genetic exchange,
has rarely been evaluated quantitatively compared to Autosomes. This genome-wide
limitation of gene flow is essential for understanding the complete separation
of species, and thus speciation. Here, we develop a mainland-island model of secondary
contact between hybridizing species of an XY (or ZW) sexual system. We obtain
theoretical predictions for the frequency of introgressed alleles, and the strength
of the barrier to neutral gene flow for the two types of chromosomes carrying
multiple interspecific barrier loci. Theoretical predictions are obtained for
scenarios where introgressed alleles are rare. We show that the same analytical
expressions apply for sex chromosomes and autosomes, but with different sex-averaged
effective parameters. The specific features of sex chromosomes (hemizygosity and
absence of recombination in the heterogametic sex) lead to reduced levels of introgression
on the X (or Z) compared to autosomes. This effect can be enhanced by certain
types of sex-biased forces, but it remains overall small (except when alleles
causing incompatibilities are recessive). We discuss these predictions in the
light of empirical data comprising model-based tests of introgression and cline
surveys in various biological systems.
acknowledged_ssus:
- _id: ScienComp
acknowledgement: "The computations were performed with the IST Austria High-Performance
Computing (HPC) Cluster and the Institut Français de Bioinformatique (IFB) Core
Cluster. We are grateful to Nick Barton and Beatriz Vicoso for critical comments
on the model and the manuscript. We also thank Brian Charlesworth, Stuart Baird,
and an anonymous reviewer for insightful comments.\r\nC.F. was supported by an Austrian
Science Foundation FWF grant (Project M 2463-B29)."
article_number: iyaa025
article_processing_charge: No
article_type: original
author:
- first_name: Christelle
full_name: Fraisse, Christelle
id: 32DF5794-F248-11E8-B48F-1D18A9856A87
last_name: Fraisse
orcid: 0000-0001-8441-5075
- first_name: Himani
full_name: Sachdeva, Himani
id: 42377A0A-F248-11E8-B48F-1D18A9856A87
last_name: Sachdeva
citation:
ama: 'Fraisse C, Sachdeva H. The rates of introgression and barriers to genetic
exchange between hybridizing species: Sex chromosomes vs autosomes. Genetics.
2021;217(2). doi:10.1093/genetics/iyaa025'
apa: 'Fraisse, C., & Sachdeva, H. (2021). The rates of introgression and barriers
to genetic exchange between hybridizing species: Sex chromosomes vs autosomes.
Genetics. Genetics Society of America. https://doi.org/10.1093/genetics/iyaa025'
chicago: 'Fraisse, Christelle, and Himani Sachdeva. “The Rates of Introgression
and Barriers to Genetic Exchange between Hybridizing Species: Sex Chromosomes
vs Autosomes.” Genetics. Genetics Society of America, 2021. https://doi.org/10.1093/genetics/iyaa025.'
ieee: 'C. Fraisse and H. Sachdeva, “The rates of introgression and barriers to genetic
exchange between hybridizing species: Sex chromosomes vs autosomes,” Genetics,
vol. 217, no. 2. Genetics Society of America, 2021.'
ista: 'Fraisse C, Sachdeva H. 2021. The rates of introgression and barriers to genetic
exchange between hybridizing species: Sex chromosomes vs autosomes. Genetics.
217(2), iyaa025.'
mla: 'Fraisse, Christelle, and Himani Sachdeva. “The Rates of Introgression and
Barriers to Genetic Exchange between Hybridizing Species: Sex Chromosomes vs Autosomes.”
Genetics, vol. 217, no. 2, iyaa025, Genetics Society of America, 2021,
doi:10.1093/genetics/iyaa025.'
short: C. Fraisse, H. Sachdeva, Genetics 217 (2021).
corr_author: '1'
date_created: 2021-02-18T14:41:30Z
date_published: 2021-02-01T00:00:00Z
date_updated: 2026-07-28T12:39:03Z
day: '01'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1093/genetics/iyaa025
external_id:
isi:
- '000637218100005'
pmid:
- '33724409'
fulldoi: https://doi.org/10.1093/genetics/iyaa025
intvolume: ' 217'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1093/genetics/iyaa025
month: '02'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 2662AADE-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: M02463
name: Sex chromosomes and species barriers
publication: Genetics
publication_identifier:
issn:
- 1943-2631
publication_status: published
publisher: Genetics Society of America
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The rates of introgression and barriers to genetic exchange between hybridizing
species: Sex chromosomes vs autosomes'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 217
year: '2021'
...
---
OA_place: publisher
OA_type: free access
_id: '9793'
abstract:
- lang: eng
text: Astrocytes extensively infiltrate the neuropil to regulate critical aspects
of synaptic development and function. This process is regulated by transcellular
interactions between astrocytes and neurons via cell adhesion molecules. How astrocytes
coordinate developmental processes among one another to parse out the synaptic
neuropil and form non-overlapping territories is unknown. Here we identify a molecular
mechanism regulating astrocyte-astrocyte interactions during development to coordinate
astrocyte morphogenesis and gap junction coupling. We show that hepaCAM, a disease-linked,
astrocyte-enriched cell adhesion molecule, regulates astrocyte competition for
territory and morphological complexity in the developing mouse cortex. Furthermore,
conditional deletion of Hepacam from developing astrocytes significantly impairs
gap junction coupling between astrocytes and disrupts the balance between synaptic
excitation and inhibition. Mutations in HEPACAM cause megalencephalic leukoencephalopathy
with subcortical cysts in humans. Therefore, our findings suggest that disruption
of astrocyte self-organization mechanisms could be an underlying cause of neural
pathology.
acknowledgement: This work was supported by the National Institutes of Health (R01
DA047258 and R01 NS102237 to C.E., F32 NS100392 to K.T.B.) and the Holland-Trice
Brain Research Award (to C.E.). K.T.B. was supported by postdoctoral fellowships
from the Foerster-Bernstein Family and The Hartwell Foundation. The Hippenmeyer
lab was supported by the European Research Council (ERC) under the European Union’s
Horizon 2020 research and innovations program (725780 LinPro) to S.H. R.E. was supported
by Ministerio de Ciencia y Tecnología (RTI2018-093493-B-I00). We thank the Duke
Light Microscopy Core Facility, the Duke Transgenic Mouse Facility, Dr. U. Schulte
for assistance with proteomic experiments, and Dr. D. Silver for critical review
of the manuscript. Cartoon elements of figure panels were created using BioRender.com.
article_processing_charge: No
article_type: original
author:
- first_name: Katherine T.
full_name: Baldwin, Katherine T.
last_name: Baldwin
- first_name: Christabel X.
full_name: Tan, Christabel X.
last_name: Tan
- first_name: Samuel T.
full_name: Strader, Samuel T.
last_name: Strader
- first_name: Changyu
full_name: Jiang, Changyu
last_name: Jiang
- first_name: Justin T.
full_name: Savage, Justin T.
last_name: Savage
- first_name: Xabier
full_name: Elorza-Vidal, Xabier
last_name: Elorza-Vidal
- first_name: Ximena
full_name: Contreras, Ximena
id: 475990FE-F248-11E8-B48F-1D18A9856A87
last_name: Contreras
- first_name: Thomas
full_name: Rülicke, Thomas
last_name: Rülicke
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
- first_name: Raúl
full_name: Estévez, Raúl
last_name: Estévez
- first_name: Ru-Rong
full_name: Ji, Ru-Rong
last_name: Ji
- first_name: Cagla
full_name: Eroglu, Cagla
last_name: Eroglu
citation:
ama: Baldwin KT, Tan CX, Strader ST, et al. HepaCAM controls astrocyte self-organization
and coupling. Neuron. 2021;109(15):2427-2442.e10. doi:10.1016/j.neuron.2021.05.025
apa: Baldwin, K. T., Tan, C. X., Strader, S. T., Jiang, C., Savage, J. T., Elorza-Vidal,
X., … Eroglu, C. (2021). HepaCAM controls astrocyte self-organization and coupling.
Neuron. Elsevier. https://doi.org/10.1016/j.neuron.2021.05.025
chicago: Baldwin, Katherine T., Christabel X. Tan, Samuel T. Strader, Changyu Jiang,
Justin T. Savage, Xabier Elorza-Vidal, Ximena Contreras, et al. “HepaCAM Controls
Astrocyte Self-Organization and Coupling.” Neuron. Elsevier, 2021. https://doi.org/10.1016/j.neuron.2021.05.025.
ieee: K. T. Baldwin et al., “HepaCAM controls astrocyte self-organization
and coupling,” Neuron, vol. 109, no. 15. Elsevier, p. 2427–2442.e10, 2021.
ista: Baldwin KT, Tan CX, Strader ST, Jiang C, Savage JT, Elorza-Vidal X, Contreras
X, Rülicke T, Hippenmeyer S, Estévez R, Ji R-R, Eroglu C. 2021. HepaCAM controls
astrocyte self-organization and coupling. Neuron. 109(15), 2427–2442.e10.
mla: Baldwin, Katherine T., et al. “HepaCAM Controls Astrocyte Self-Organization
and Coupling.” Neuron, vol. 109, no. 15, Elsevier, 2021, p. 2427–2442.e10,
doi:10.1016/j.neuron.2021.05.025.
short: K.T. Baldwin, C.X. Tan, S.T. Strader, C. Jiang, J.T. Savage, X. Elorza-Vidal,
X. Contreras, T. Rülicke, S. Hippenmeyer, R. Estévez, R.-R. Ji, C. Eroglu, Neuron
109 (2021) 2427–2442.e10.
date_created: 2021-08-06T09:08:25Z
date_published: 2021-08-04T00:00:00Z
date_updated: 2026-07-28T12:30:05Z
day: '04'
ddc:
- '570'
department:
- _id: SiHi
doi: 10.1016/j.neuron.2021.05.025
ec_funded: 1
external_id:
isi:
- '000692851900010'
pmid:
- '34171291'
fulldoi: https://doi.org/10.1016/j.neuron.2021.05.025
intvolume: ' 109'
isi: 1
issue: '15'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.neuron.2021.05.025
month: '08'
oa: 1
oa_version: Published Version
page: 2427-2442.e10
pmid: 1
project:
- _id: 260018B0-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '725780'
name: Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development
publication: Neuron
publication_identifier:
eissn:
- 1097-4199
issn:
- 0896-6273
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: HepaCAM controls astrocyte self-organization and coupling
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 109
year: '2021'
...
---
OA_place: publisher
OA_type: free access
_id: '10363'
abstract:
- lang: eng
text: Erythropoietin enhances oxygen delivery and reduces hypoxia-induced cell death,
but its pro-thrombotic activity is problematic for use of erythropoietin in treating
hypoxia. We constructed a fusion protein that stimulates red blood cell production
and neuroprotection without triggering platelet production, a marker for thrombosis.
The protein consists of an anti-glycophorin A nanobody and an erythropoietin mutant
(L108A). The mutation reduces activation of erythropoietin receptor homodimers
that induce erythropoiesis and thrombosis, but maintains the tissue-protective
signaling. The binding of the nanobody element to glycophorin A rescues homodimeric
erythropoietin receptor activation on red blood cell precursors. In a cell proliferation
assay, the fusion protein is active at 10−14 M, allowing an estimate of the number
of receptor–ligand complexes needed for signaling. This fusion protein stimulates
erythroid cell proliferation in vitro and in mice, and shows neuroprotective activity
in vitro. Our erythropoietin fusion protein presents a novel molecule for treating
hypoxia.
acknowledgement: This work was supported by funds from the Wyss Institute for Biologically
Inspired Engineering and the Boston Biomedical Innovation Center (Pilot Award 112475;
Drive Award U54HL119145). J.L., K.M.K., D.R.B., J.C.W. and P.A.S. were supported
by the Harvard Medical School Department of Systems Biology. J.C.W. was further
supported by the Harvard Medical School Laboratory of Systems Pharmacology. A.V.,
D.R.B. and P.A.S. were further supported by the Wyss Institute for Biologically
Inspired Engineering. N.G.G. was sponsored by the Army Research Office under Grant
Number W911NF-17-2-0092. The views and conclusions contained in this document are
those of the authors and should not be interpreted as representing the official
policies, either expressed or implied, of the Army Research Office or the U.S. Government.
The U.S. Government is authorized to reproduce and distribute reprints for Government
purposes notwithstanding any copyright notation herein. We sincerely thank Amanda
Graveline and the Wyss Institute at Harvard for their scientific support.
article_number: gzab025
article_processing_charge: No
article_type: original
author:
- first_name: Jungmin
full_name: Lee, Jungmin
last_name: Lee
- first_name: Andyna
full_name: Vernet, Andyna
last_name: Vernet
- first_name: Nathalie
full_name: Gruber, Nathalie
id: 2C9C8316-AA17-11E9-B5C2-8BC2E5697425
last_name: Gruber
- first_name: Kasia M.
full_name: Kready, Kasia M.
last_name: Kready
- first_name: Devin R.
full_name: Burrill, Devin R.
last_name: Burrill
- first_name: Jeffrey C.
full_name: Way, Jeffrey C.
last_name: Way
- first_name: Pamela A.
full_name: Silver, Pamela A.
last_name: Silver
citation:
ama: Lee J, Vernet A, Gruber N, et al. Rational engineering of an erythropoietin
fusion protein to treat hypoxia. Protein Engineering, Design and Selection.
2021;34. doi:10.1093/protein/gzab025
apa: Lee, J., Vernet, A., Gruber, N., Kready, K. M., Burrill, D. R., Way, J. C.,
& Silver, P. A. (2021). Rational engineering of an erythropoietin fusion protein
to treat hypoxia. Protein Engineering, Design and Selection. Oxford University
Press. https://doi.org/10.1093/protein/gzab025
chicago: Lee, Jungmin, Andyna Vernet, Nathalie Gruber, Kasia M. Kready, Devin R.
Burrill, Jeffrey C. Way, and Pamela A. Silver. “Rational Engineering of an Erythropoietin
Fusion Protein to Treat Hypoxia.” Protein Engineering, Design and Selection.
Oxford University Press, 2021. https://doi.org/10.1093/protein/gzab025.
ieee: J. Lee et al., “Rational engineering of an erythropoietin fusion protein
to treat hypoxia,” Protein Engineering, Design and Selection, vol. 34.
Oxford University Press, 2021.
ista: Lee J, Vernet A, Gruber N, Kready KM, Burrill DR, Way JC, Silver PA. 2021.
Rational engineering of an erythropoietin fusion protein to treat hypoxia. Protein
Engineering, Design and Selection. 34, gzab025.
mla: Lee, Jungmin, et al. “Rational Engineering of an Erythropoietin Fusion Protein
to Treat Hypoxia.” Protein Engineering, Design and Selection, vol. 34,
gzab025, Oxford University Press, 2021, doi:10.1093/protein/gzab025.
short: J. Lee, A. Vernet, N. Gruber, K.M. Kready, D.R. Burrill, J.C. Way, P.A. Silver,
Protein Engineering, Design and Selection 34 (2021).
date_created: 2021-11-28T23:01:28Z
date_published: 2021-11-01T00:00:00Z
date_updated: 2026-07-28T12:27:59Z
day: '01'
ddc:
- '570'
department:
- _id: CaGu
doi: 10.1093/protein/gzab025
external_id:
isi:
- '000746596900001'
pmid:
- '34725710'
fulldoi: https://doi.org/10.1093/protein/gzab025
intvolume: ' 34'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1093/protein/gzab025
month: '11'
oa: 1
oa_version: Published Version
pmid: 1
publication: Protein Engineering, Design and Selection
publication_identifier:
eissn:
- 1741-0134
issn:
- 1741-0126
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Rational engineering of an erythropoietin fusion protein to treat hypoxia
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2021'
...
---
OA_type: closed access
_id: '10809'
abstract:
- lang: eng
text: Thermoelectric materials are engines that convert heat into an electrical
current. Intuitively, the efficiency of this process depends on how many electrons
(charge carriers) can move and how easily they do so, how much energy those moving
electrons transport, and how easily the temperature gradient is maintained. In
terms of material properties, an excellent thermoelectric material requires a
high electrical conductivity σ, a high Seebeck coefficient S (a measure of the
induced thermoelectric voltage as a function of temperature gradient), and a low
thermal conductivity κ. The challenge is that these three properties are strongly
interrelated in a conflicting manner (1). On page 722 of this issue, Roychowdhury
et al. (2) have found a way to partially break these ties in silver antimony telluride
(AgSbTe2) with the addition of cadmium (Cd) cations, which increase the ordering
in this inherently disordered thermoelectric material.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Yu
full_name: Liu, Yu
id: 2A70014E-F248-11E8-B48F-1D18A9856A87
last_name: Liu
orcid: 0000-0001-7313-6740
- first_name: Maria
full_name: Ibáñez, Maria
id: 43C61214-F248-11E8-B48F-1D18A9856A87
last_name: Ibáñez
orcid: 0000-0001-5013-2843
citation:
ama: Liu Y, Ibáñez M. Tidying up the mess. Science. 2021;371(6530):678-679.
doi:10.1126/science.abg0886
apa: Liu, Y., & Ibáñez, M. (2021). Tidying up the mess. Science. American
Association for the Advancement of Science. https://doi.org/10.1126/science.abg0886
chicago: Liu, Yu, and Maria Ibáñez. “Tidying up the Mess.” Science. American
Association for the Advancement of Science, 2021. https://doi.org/10.1126/science.abg0886.
ieee: Y. Liu and M. Ibáñez, “Tidying up the mess,” Science, vol. 371, no.
6530. American Association for the Advancement of Science, pp. 678–679, 2021.
ista: Liu Y, Ibáñez M. 2021. Tidying up the mess. Science. 371(6530), 678–679.
mla: Liu, Yu, and Maria Ibáñez. “Tidying up the Mess.” Science, vol. 371,
no. 6530, American Association for the Advancement of Science, 2021, pp. 678–79,
doi:10.1126/science.abg0886.
short: Y. Liu, M. Ibáñez, Science 371 (2021) 678–679.
corr_author: '1'
date_created: 2022-03-03T09:51:48Z
date_published: 2021-02-12T00:00:00Z
date_updated: 2026-07-28T12:16:17Z
day: '12'
department:
- _id: MaIb
doi: 10.1126/science.abg0886
external_id:
isi:
- '000617551600027'
pmid:
- '33574201'
fulldoi: https://doi.org/10.1126/science.abg0886
intvolume: ' 371'
isi: 1
issue: '6530'
language:
- iso: eng
month: '02'
oa_version: None
page: 678-679
pmid: 1
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Tidying up the mess
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 371
year: '2021'
...
---
_id: '8317'
abstract:
- lang: eng
text: When can a polyomino piece of paper be folded into a unit cube? Prior work
studied tree-like polyominoes, but polyominoes with holes remain an intriguing
open problem. We present sufficient conditions for a polyomino with one or several
holes to fold into a cube, and conditions under which cube folding is impossible.
In particular, we show that all but five special “basic” holes guarantee foldability.
acknowledgement: This research was performed in part at the 33rd Bellairs Winter Workshop
on Computational Geometry. We thank all other participants for a fruitful atmosphere.
H. Akitaya was supported by NSF CCF-1422311 & 1423615. Z. Masárová was partially
funded by Wittgenstein Prize, Austrian Science Fund (FWF), grant no. Z 342-N31.
article_number: '101700'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Oswin
full_name: Aichholzer, Oswin
last_name: Aichholzer
- first_name: Hugo A.
full_name: Akitaya, Hugo A.
last_name: Akitaya
- first_name: Kenneth C.
full_name: Cheung, Kenneth C.
last_name: Cheung
- first_name: Erik D.
full_name: Demaine, Erik D.
last_name: Demaine
- first_name: Martin L.
full_name: Demaine, Martin L.
last_name: Demaine
- first_name: Sándor P.
full_name: Fekete, Sándor P.
last_name: Fekete
- first_name: Linda
full_name: Kleist, Linda
last_name: Kleist
- first_name: Irina
full_name: Kostitsyna, Irina
last_name: Kostitsyna
- first_name: Maarten
full_name: Löffler, Maarten
last_name: Löffler
- first_name: Zuzana
full_name: Masárová, Zuzana
id: 45CFE238-F248-11E8-B48F-1D18A9856A87
last_name: Masárová
orcid: 0000-0002-6660-1322
- first_name: Klara
full_name: Mundilova, Klara
last_name: Mundilova
- first_name: Christiane
full_name: Schmidt, Christiane
last_name: Schmidt
citation:
ama: 'Aichholzer O, Akitaya HA, Cheung KC, et al. Folding polyominoes with holes
into a cube. Computational Geometry: Theory and Applications. 2021;93.
doi:10.1016/j.comgeo.2020.101700'
apa: 'Aichholzer, O., Akitaya, H. A., Cheung, K. C., Demaine, E. D., Demaine, M.
L., Fekete, S. P., … Schmidt, C. (2021). Folding polyominoes with holes into a
cube. Computational Geometry: Theory and Applications. Elsevier. https://doi.org/10.1016/j.comgeo.2020.101700'
chicago: 'Aichholzer, Oswin, Hugo A. Akitaya, Kenneth C. Cheung, Erik D. Demaine,
Martin L. Demaine, Sándor P. Fekete, Linda Kleist, et al. “Folding Polyominoes
with Holes into a Cube.” Computational Geometry: Theory and Applications.
Elsevier, 2021. https://doi.org/10.1016/j.comgeo.2020.101700.'
ieee: 'O. Aichholzer et al., “Folding polyominoes with holes into a cube,”
Computational Geometry: Theory and Applications, vol. 93. Elsevier, 2021.'
ista: 'Aichholzer O, Akitaya HA, Cheung KC, Demaine ED, Demaine ML, Fekete SP, Kleist
L, Kostitsyna I, Löffler M, Masárová Z, Mundilova K, Schmidt C. 2021. Folding
polyominoes with holes into a cube. Computational Geometry: Theory and Applications.
93, 101700.'
mla: 'Aichholzer, Oswin, et al. “Folding Polyominoes with Holes into a Cube.” Computational
Geometry: Theory and Applications, vol. 93, 101700, Elsevier, 2021, doi:10.1016/j.comgeo.2020.101700.'
short: 'O. Aichholzer, H.A. Akitaya, K.C. Cheung, E.D. Demaine, M.L. Demaine, S.P.
Fekete, L. Kleist, I. Kostitsyna, M. Löffler, Z. Masárová, K. Mundilova, C. Schmidt,
Computational Geometry: Theory and Applications 93 (2021).'
corr_author: '1'
date_created: 2020-08-30T22:01:09Z
date_published: 2021-02-01T00:00:00Z
date_updated: 2026-07-28T13:08:48Z
day: '01'
department:
- _id: HeEd
doi: 10.1016/j.comgeo.2020.101700
external_id:
arxiv:
- '1910.09917'
isi:
- '000579185100004'
fulldoi: https://doi.org/10.1016/j.comgeo.2020.101700
intvolume: ' 93'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1910.09917v3
month: '02'
oa: 1
oa_version: Preprint
project:
- _id: 268116B8-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z00342
name: Mathematics, Computer Science
publication: 'Computational Geometry: Theory and Applications'
publication_identifier:
eissn:
- 1879-081X
issn:
- 0925-7721
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
record:
- id: '6989'
relation: shorter_version
status: public
scopus_import: '1'
status: public
title: Folding polyominoes with holes into a cube
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 93
year: '2021'
...
---
OA_place: repository
OA_type: green
_id: '10912'
abstract:
- lang: eng
text: Brain dynamics display collective phenomena as diverse as neuronal oscillations
and avalanches. Oscillations are rhythmic, with fluctuations occurring at a characteristic
scale, whereas avalanches are scale-free cascades of neural activity. Here we
show that such antithetic features can coexist in a very generic class of adaptive
neural networks. In the most simple yet fully microscopic model from this class
we make direct contact with human brain resting-state activity recordings via
tractable inference of the model's two essential parameters. The inferred model
quantitatively captures the dynamics over a broad range of scales, from single
sensor fluctuations, collective behaviors of nearly-synchronous extreme events
on multiple sensors, to neuronal avalanches unfolding over multiple sensors across
multiple time-bins. Importantly, the inferred parameters correlate with model-independent
signatures of "closeness to criticality", suggesting that the coexistence of scale-specific
(neural oscillations) and scale-free (neuronal avalanches) dynamics in brain activity
occurs close to a non-equilibrium critical point at the onset of self-sustained
oscillations.
acknowledgement: "FL acknowledges support from the European Union’s Horizon 2020 research
and innovation program under the Marie Sklodowska-Curie Grant Agreement No. 754411.
GT\r\nacknowledges the support of the Austrian Science Fund (FWF) under Stand-Alone
Grant\r\nNo. P34015."
article_number: '2108.06686'
article_processing_charge: No
arxiv: 1
author:
- first_name: Fabrizio
full_name: Lombardi, Fabrizio
id: A057D288-3E88-11E9-986D-0CF4E5697425
last_name: Lombardi
orcid: 0000-0003-2623-5249
- first_name: Selver
full_name: Pepic, Selver
id: F93245C4-C3CA-11E9-B4F0-C6F4E5697425
last_name: Pepic
- first_name: Oren
full_name: Shriki, Oren
last_name: Shriki
- first_name: Gašper
full_name: Tkačik, Gašper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkačik
orcid: 0000-0002-6699-1455
- first_name: Daniele
full_name: De Martino, Daniele
last_name: De Martino
citation:
ama: Lombardi F, Pepic S, Shriki O, Tkačik G, De Martino D. Quantifying the coexistence
of neuronal oscillations and avalanches. doi:10.48550/ARXIV.2108.06686
apa: Lombardi, F., Pepic, S., Shriki, O., Tkačik, G., & De Martino, D. (n.d.).
Quantifying the coexistence of neuronal oscillations and avalanches. arXiv. https://doi.org/10.48550/ARXIV.2108.06686
chicago: Lombardi, Fabrizio, Selver Pepic, Oren Shriki, Gašper Tkačik, and Daniele
De Martino. “Quantifying the Coexistence of Neuronal Oscillations and Avalanches.”
arXiv, n.d. https://doi.org/10.48550/ARXIV.2108.06686.
ieee: F. Lombardi, S. Pepic, O. Shriki, G. Tkačik, and D. De Martino, “Quantifying
the coexistence of neuronal oscillations and avalanches.” arXiv.
ista: Lombardi F, Pepic S, Shriki O, Tkačik G, De Martino D. Quantifying the coexistence
of neuronal oscillations and avalanches. 2108.06686.
mla: Lombardi, Fabrizio, et al. Quantifying the Coexistence of Neuronal Oscillations
and Avalanches. 2108.06686, arXiv, doi:10.48550/ARXIV.2108.06686.
short: F. Lombardi, S. Pepic, O. Shriki, G. Tkačik, D. De Martino, (n.d.).
date_created: 2022-03-21T11:41:28Z
date_published: 2021-08-17T00:00:00Z
date_updated: 2026-07-29T06:53:41Z
day: '17'
ddc:
- '570'
department:
- _id: GaTk
doi: 10.48550/ARXIV.2108.06686
ec_funded: 1
external_id:
arxiv:
- '2108.06686'
fulldoi: https://doi.org/10.48550/ARXIV.2108.06686
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/2108.06686
month: '08'
oa: 1
oa_version: Preprint
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
- _id: 626c45b5-2b32-11ec-9570-e509828c1ba6
grant_number: P34015
name: Efficient coding with biophysical realism
publication_status: submitted
publisher: arXiv
related_material:
record:
- id: '12762'
relation: later_version
status: public
status: public
title: Quantifying the coexistence of neuronal oscillations and avalanches
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2021'
...
---
_id: '10080'
abstract:
- lang: eng
text: Hippocampal and neocortical neural activity is modulated by the position of
the individual in space. While hippocampal neurons provide the basis for a spatial
map, prefrontal cortical neurons generalize over environmental features. Whether
these generalized representations result from a bidirectional interaction with,
or are mainly derived from hippocampal spatial representations is not known. By
examining simultaneously recorded hippocampal and medial prefrontal neurons, we
observed that prefrontal spatial representations show a delayed coherence with
hippocampal ones. We also identified subpopulations of cells in the hippocampus
and medial prefrontal cortex that formed functional cross-area couplings; these
resembled the optimal connections predicted by a probabilistic model of spatial
information transfer and generalization. Moreover, cross-area couplings were strongest
and had the shortest delay preceding spatial decision-making. Our results suggest
that generalized spatial coding in the medial prefrontal cortex is inherited from
spatial representations in the hippocampus, and that the routing of information
can change dynamically with behavioral demands.
acknowledgement: We thank Federico Stella for invaluable suggestions and discussions.
We thank Yosman BapatDhar and Andrea Cumpelik for comments, help and suggestions
on the exposure of the text. We thank Predrag Živadinović and Juliana Couras for
comments on the text and the figures. This work was supported by the EU-FP7 MC-ITN
IN-SENS (grant 607616).
article_processing_charge: No
author:
- first_name: Michele
full_name: Nardin, Michele
id: 30BD0376-F248-11E8-B48F-1D18A9856A87
last_name: Nardin
orcid: 0000-0001-8849-6570
- first_name: Karola
full_name: Käfer, Karola
id: 2DAA49AA-F248-11E8-B48F-1D18A9856A87
last_name: Käfer
- first_name: Jozsef L
full_name: Csicsvari, Jozsef L
id: 3FA14672-F248-11E8-B48F-1D18A9856A87
last_name: Csicsvari
orcid: 0000-0002-5193-4036
biorxivid: 1
citation:
ama: Nardin M, Käfer K, Csicsvari JL. The generalized spatial representation in
the prefrontal cortex is inherited from the hippocampus. bioRxiv. doi:10.1101/2021.09.30.462269
apa: Nardin, M., Käfer, K., & Csicsvari, J. L. (n.d.). The generalized spatial
representation in the prefrontal cortex is inherited from the hippocampus. bioRxiv.
https://doi.org/10.1101/2021.09.30.462269
chicago: Nardin, Michele, Karola Käfer, and Jozsef L Csicsvari. “The Generalized
Spatial Representation in the Prefrontal Cortex Is Inherited from the Hippocampus.”
BioRxiv, n.d. https://doi.org/10.1101/2021.09.30.462269.
ieee: M. Nardin, K. Käfer, and J. L. Csicsvari, “The generalized spatial representation
in the prefrontal cortex is inherited from the hippocampus,” bioRxiv. .
ista: Nardin M, Käfer K, Csicsvari JL. The generalized spatial representation in
the prefrontal cortex is inherited from the hippocampus. bioRxiv, 10.1101/2021.09.30.462269.
mla: Nardin, Michele, et al. “The Generalized Spatial Representation in the Prefrontal
Cortex Is Inherited from the Hippocampus.” BioRxiv, doi:10.1101/2021.09.30.462269.
short: M. Nardin, K. Käfer, J.L. Csicsvari, BioRxiv (n.d.).
das_tickbox: '1'
date_created: 2021-10-04T06:28:32Z
date_published: 2021-10-02T00:00:00Z
date_updated: 2026-07-29T06:33:53Z
day: '02'
department:
- _id: GradSch
- _id: JoCs
doi: 10.1101/2021.09.30.462269
ec_funded: 1
external_id:
biorxivid:
- 10.1101/2021.09.30.462269
fulldoi: https://doi.org/10.1101/2021.09.30.462269
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1101/2021.09.30.462269
month: '10'
oa: 1
oa_version: Preprint
project:
- _id: 257BBB4C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '607616'
name: inter-and intracellular signalling in schizophrenia
publication: bioRxiv
publication_status: submitted
status: public
title: The generalized spatial representation in the prefrontal cortex is inherited
from the hippocampus
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2021'
...
---
_id: '9905'
abstract:
- lang: eng
text: Vaccines are thought to be the best available solution for controlling the
ongoing SARS-CoV-2 pandemic. However, the emergence of vaccine-resistant strains
may come too rapidly for current vaccine developments to alleviate the health,
economic and social consequences of the pandemic. To quantify and characterize
the risk of such a scenario, we created a SIR-derived model with initial stochastic
dynamics of the vaccine-resistant strain to study the probability of its emergence
and establishment. Using parameters realistically resembling SARS-CoV-2 transmission,
we model a wave-like pattern of the pandemic and consider the impact of the rate
of vaccination and the strength of non-pharmaceutical intervention measures on
the probability of emergence of a resistant strain. As expected, we found that
a fast rate of vaccination decreases the probability of emergence of a resistant
strain. Counterintuitively, when a relaxation of non-pharmaceutical interventions
happened at a time when most individuals of the population have already been vaccinated
the probability of emergence of a resistant strain was greatly increased. Consequently,
we show that a period of transmission reduction close to the end of the vaccination
campaign can substantially reduce the probability of resistant strain establishment.
Our results suggest that policymakers and individuals should consider maintaining
non-pharmaceutical interventions and transmission-reducing behaviours throughout
the entire vaccination period.
acknowledgement: We thank Alexey Kondrashov, Nick Machnik, Raimundo Julian Saona Urmeneta,
Gasper Tkacik and Nick Barton for fruitful discussions. We also thank participants
of EvoLunch seminar at IST Austria and the internal seminar at the Banco de España
for useful comments. The opinions expressed in this document are exclusively of
the authors and, therefore, do not necessarily coincide with those of the Banco
de España or the Eurosystem. ETD is supported by the Swiss National Science and
Louis Jeantet Foundation. The work of FAK was in part supported by the ERC Consolidator
Grant (771209-CharFL).
article_number: '15729'
article_processing_charge: Yes
article_type: original
author:
- first_name: Simon
full_name: Rella, Simon
id: B4765ACA-AA38-11E9-AC9A-0930E6697425
last_name: Rella
- first_name: Yuliya A.
full_name: Kulikova, Yuliya A.
last_name: Kulikova
- first_name: Emmanouil T.
full_name: Dermitzakis, Emmanouil T.
last_name: Dermitzakis
- first_name: Fyodor
full_name: Kondrashov, Fyodor
id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
last_name: Kondrashov
orcid: 0000-0001-8243-4694
citation:
ama: Rella S, Kulikova YA, Dermitzakis ET, Kondrashov F. Rates of SARS-CoV-2 transmission
and vaccination impact the fate of vaccine-resistant strains. Scientific Reports.
2021;11(1). doi:10.1038/s41598-021-95025-3
apa: Rella, S., Kulikova, Y. A., Dermitzakis, E. T., & Kondrashov, F. (2021).
Rates of SARS-CoV-2 transmission and vaccination impact the fate of vaccine-resistant
strains. Scientific Reports. Springer Nature. https://doi.org/10.1038/s41598-021-95025-3
chicago: Rella, Simon, Yuliya A. Kulikova, Emmanouil T. Dermitzakis, and Fyodor
Kondrashov. “Rates of SARS-CoV-2 Transmission and Vaccination Impact the Fate
of Vaccine-Resistant Strains.” Scientific Reports. Springer Nature, 2021.
https://doi.org/10.1038/s41598-021-95025-3.
ieee: S. Rella, Y. A. Kulikova, E. T. Dermitzakis, and F. Kondrashov, “Rates of
SARS-CoV-2 transmission and vaccination impact the fate of vaccine-resistant strains,”
Scientific Reports, vol. 11, no. 1. Springer Nature, 2021.
ista: Rella S, Kulikova YA, Dermitzakis ET, Kondrashov F. 2021. Rates of SARS-CoV-2
transmission and vaccination impact the fate of vaccine-resistant strains. Scientific
Reports. 11(1), 15729.
mla: Rella, Simon, et al. “Rates of SARS-CoV-2 Transmission and Vaccination Impact
the Fate of Vaccine-Resistant Strains.” Scientific Reports, vol. 11, no.
1, 15729, Springer Nature, 2021, doi:10.1038/s41598-021-95025-3.
short: S. Rella, Y.A. Kulikova, E.T. Dermitzakis, F. Kondrashov, Scientific Reports
11 (2021).
date_created: 2021-08-15T22:01:26Z
date_published: 2021-07-30T00:00:00Z
date_updated: 2026-07-29T12:57:49Z
day: '30'
ddc:
- '570'
- '610'
department:
- _id: FyKo
doi: 10.1038/s41598-021-95025-3
ec_funded: 1
external_id:
isi:
- '000683329100001'
pmid:
- '34330988'
file:
- access_level: open_access
checksum: ac86892ed17e6724c7251844da5cef5c
content_type: application/pdf
creator: asandaue
date_created: 2021-08-16T11:36:49Z
date_updated: 2021-08-16T11:36:49Z
file_id: '9927'
file_name: 2021_ScientificReports_Rella.pdf
file_size: 3432001
relation: main_file
success: 1
file_date_updated: 2021-08-16T11:36:49Z
fulldoi: https://doi.org/10.1038/s41598-021-95025-3
has_accepted_license: '1'
intvolume: ' 11'
isi: 1
issue: '1'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 26580278-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '771209'
name: Characterizing the fitness landscape on population and global scales
publication: Scientific Reports
publication_identifier:
eissn:
- 2045-2322
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
link:
- description: News on IST Website
relation: press_release
url: https://ist.ac.at/en/news/counterintuitive-dynamics-threaten-the-end-of-the-pandemic/
record:
- id: '20811'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Rates of SARS-CoV-2 transmission and vaccination impact the fate of vaccine-resistant
strains
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 11
year: '2021'
...
---
OA_place: publisher
_id: '9418'
abstract:
- lang: eng
text: "Deep learning is best known for its empirical success across a wide range
of applications\r\nspanning computer vision, natural language processing and speech.
Of equal significance,\r\nthough perhaps less known, are its ramifications for
learning theory: deep networks have\r\nbeen observed to perform surprisingly well
in the high-capacity regime, aka the overfitting\r\nor underspecified regime.
Classically, this regime on the far right of the bias-variance curve\r\nis associated
with poor generalisation; however, recent experiments with deep networks\r\nchallenge
this view.\r\n\r\nThis thesis is devoted to investigating various aspects of underspecification
in deep learning.\r\nFirst, we argue that deep learning models are underspecified
on two levels: a) any given\r\ntraining dataset can be fit by many different functions,
and b) any given function can be\r\nexpressed by many different parameter configurations.
We refer to the second kind of\r\nunderspecification as parameterisation redundancy
and we precisely characterise its extent.\r\nSecond, we characterise the implicit
criteria (the inductive bias) that guide learning in the\r\nunderspecified regime.
Specifically, we consider a nonlinear but tractable classification\r\nsetting,
and show that given the choice, neural networks learn classifiers with a large
margin.\r\nThird, we consider learning scenarios where the inductive bias is not
by itself sufficient to\r\ndeal with underspecification. We then study different
ways of ‘tightening the specification’: i)\r\nIn the setting of representation
learning with variational autoencoders, we propose a hand-\r\ncrafted regulariser
based on mutual information. ii) In the setting of binary classification, we\r\nconsider
soft-label (real-valued) supervision. We derive a generalisation bound for linear\r\nnetworks
supervised in this way and verify that soft labels facilitate fast learning. Finally,
we\r\nexplore an application of soft-label supervision to the training of multi-exit
models."
acknowledged_ssus:
- _id: ScienComp
- _id: CampIT
- _id: E-Lib
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Phuong
full_name: Bui Thi Mai, Phuong
id: 3EC6EE64-F248-11E8-B48F-1D18A9856A87
last_name: Bui Thi Mai
citation:
ama: Phuong M. Underspecification in deep learning. 2021. doi:10.15479/AT:ISTA:9418
apa: Phuong, M. (2021). Underspecification in deep learning. Institute of
Science and Technology Austria. https://doi.org/10.15479/AT:ISTA:9418
chicago: Phuong, Mary. “Underspecification in Deep Learning.” Institute of Science
and Technology Austria, 2021. https://doi.org/10.15479/AT:ISTA:9418.
ieee: M. Phuong, “Underspecification in deep learning,” Institute of Science and
Technology Austria, 2021.
ista: Phuong M. 2021. Underspecification in deep learning. Institute of Science
and Technology Austria.
mla: Phuong, Mary. Underspecification in Deep Learning. Institute of Science
and Technology Austria, 2021, doi:10.15479/AT:ISTA:9418.
short: M. Phuong, Underspecification in Deep Learning, Institute of Science and
Technology Austria, 2021.
corr_author: '1'
date_created: 2021-05-24T13:06:23Z
date_published: 2021-05-30T00:00:00Z
date_updated: 2026-07-30T05:33:52Z
day: '30'
ddc:
- '000'
degree_awarded: PhD
department:
- _id: GradSch
- _id: ChLa
doi: 10.15479/AT:ISTA:9418
doi_confirm: '1'
file:
- access_level: open_access
checksum: 4f0abe64114cfed264f9d36e8d1197e3
content_type: application/pdf
creator: bphuong
date_created: 2021-05-24T11:22:29Z
date_updated: 2021-05-24T11:22:29Z
file_id: '9419'
file_name: mph-thesis-v519-pdfimages.pdf
file_size: 2673905
relation: main_file
success: 1
- access_level: closed
checksum: f5699e876bc770a9b0df8345a77720a2
content_type: application/zip
creator: bphuong
date_created: 2021-05-24T11:56:02Z
date_updated: 2021-05-24T11:56:02Z
file_id: '9420'
file_name: thesis.zip
file_size: 92995100
relation: source_file
file_date_updated: 2021-05-24T11:56:02Z
fulldoi: https://doi.org/10.15479/AT:ISTA:9418
has_accepted_license: '1'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: '125'
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
record:
- id: '7435'
relation: part_of_dissertation
status: deleted
- id: '7481'
relation: part_of_dissertation
status: public
- id: '9416'
relation: part_of_dissertation
status: public
- id: '7479'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Christoph
full_name: Lampert, Christoph
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
title: Underspecification in deep learning
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2021'
...