--- _id: '10067' abstract: - lang: eng text: The search for novel entangled phases of matter has lead to the recent discovery of a new class of “entanglement transitions,” exemplified by random tensor networks and monitored quantum circuits. Most known examples can be understood as some classical ordering transitions in an underlying statistical mechanics model, where entanglement maps onto the free-energy cost of inserting a domain wall. In this paper we study the possibility of entanglement transitions driven by physics beyond such statistical mechanics mappings. Motivated by recent applications of neural-network-inspired variational Ansätze, we investigate under what conditions on the variational parameters these Ansätze can capture an entanglement transition. We study the entanglement scaling of short-range restricted Boltzmann machine (RBM) quantum states with random phases. For uncorrelated random phases, we analytically demonstrate the absence of an entanglement transition and reveal subtle finite-size effects in finite-size numerical simulations. Introducing phases with correlations decaying as 1/r^α in real space, we observe three regions with a different scaling of entanglement entropy depending on the exponent α. We study the nature of the transition between these regions, finding numerical evidence for critical behavior. Our work establishes the presence of long-range correlated phases in RBM-based wave functions as a required ingredient for entanglement transitions. acknowledgement: We would like to thank S. De Nicola, P. Brighi, and V. Karle for fruitful discussions and valuable feedback on the manuscript. R.M. and M.S. acknowledge support by the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program (Grant Agreement No. 850899). R.V. acknowledges support from the US Department of Energy, Office of Science, Basic Energy Sciences, under Early Career Award No. DE-SC0019168, and the Alfred P. Sloan Foundation through a Sloan Research Fellowship. article_number: '104205' article_processing_charge: No article_type: original arxiv: 1 author: - first_name: Raimel A full_name: Medina Ramos, Raimel A id: CE680B90-D85A-11E9-B684-C920E6697425 last_name: Medina Ramos orcid: 0000-0002-5383-2869 - first_name: Romain full_name: Vasseur, Romain last_name: Vasseur - first_name: Maksym full_name: Serbyn, Maksym id: 47809E7E-F248-11E8-B48F-1D18A9856A87 last_name: Serbyn orcid: 0000-0002-2399-5827 citation: ama: Medina Ramos RA, Vasseur R, Serbyn M. Entanglement transitions from restricted Boltzmann machines. Physical Review B. 2021;104(10). doi:10.1103/physrevb.104.104205 apa: Medina Ramos, R. A., Vasseur, R., & Serbyn, M. (2021). Entanglement transitions from restricted Boltzmann machines. Physical Review B. American Physical Society. https://doi.org/10.1103/physrevb.104.104205 chicago: Medina Ramos, Raimel A, Romain Vasseur, and Maksym Serbyn. “Entanglement Transitions from Restricted Boltzmann Machines.” Physical Review B. American Physical Society, 2021. https://doi.org/10.1103/physrevb.104.104205. ieee: R. A. Medina Ramos, R. Vasseur, and M. Serbyn, “Entanglement transitions from restricted Boltzmann machines,” Physical Review B, vol. 104, no. 10. American Physical Society, 2021. ista: Medina Ramos RA, Vasseur R, Serbyn M. 2021. Entanglement transitions from restricted Boltzmann machines. Physical Review B. 104(10), 104205. mla: Medina Ramos, Raimel A., et al. “Entanglement Transitions from Restricted Boltzmann Machines.” Physical Review B, vol. 104, no. 10, 104205, American Physical Society, 2021, doi:10.1103/physrevb.104.104205. short: R.A. Medina Ramos, R. Vasseur, M. Serbyn, Physical Review B 104 (2021). corr_author: '1' date_created: 2021-10-02T09:03:42Z date_published: 2021-09-30T00:00:00Z date_updated: 2026-10-02T11:36:06Z day: '30' department: - _id: MaSe doi: 10.1103/physrevb.104.104205 ec_funded: 1 external_id: arxiv: - '2107.05735' isi: - '000704414400002' fulldoi: https://doi.org/10.1103/physrevb.104.104205 intvolume: ' 104' isi: 1 issue: '10' language: - iso: eng main_file_link: - open_access: '1' url: https://arxiv.org/abs/2107.05735 month: '09' oa: 1 oa_version: Preprint project: - _id: 23841C26-32DE-11EA-91FC-C7463DDC885E call_identifier: H2020 grant_number: '850899' name: 'Non-Ergodic Quantum Matter: Universality, Dynamics and Control' publication: Physical Review B publication_identifier: eissn: - 2469-9969 issn: - 2469-9950 publication_status: published publisher: American Physical Society quality_controlled: '1' related_material: record: - id: '17208' relation: dissertation_contains status: public scopus_import: '1' status: public title: Entanglement transitions from restricted Boltzmann machines type: journal_article user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8 volume: 104 year: '2021' ... --- _id: '10545' abstract: - lang: eng text: Classical models with complex energy landscapes represent a perspective avenue for the near-term application of quantum simulators. Until now, many theoretical works studied the performance of quantum algorithms for models with a unique ground state. However, when the classical problem is in a so-called clustering phase, the ground state manifold is highly degenerate. As an example, we consider a 3-XORSAT model defined on simple hypergraphs. The degeneracy of classical ground state manifold translates into the emergence of an extensive number of Z2 symmetries, which remain intact even in the presence of a quantum transverse magnetic field. We establish a general duality approach that restricts the quantum problem to a given sector of conserved Z2 charges and use it to study how the outcome of the quantum adiabatic algorithm depends on the hypergraph geometry. We show that the tree hypergraph which corresponds to a classically solvable instance of the 3-XORSAT problem features a constant gap, whereas the closed hypergraph encounters a second-order phase transition with a gap vanishing as a power-law in the problem size. The duality developed in this work provides a practical tool for studies of quantum models with classically degenerate energy manifold and reveals potential connections between glasses and gauge theories. acknowledgement: We would like to thank S. De Nicola, A. Michaidilis, T. Gulden, Y. Nez-Fernndez, P. Brighi, and S. Sack for fruitful discussions and valuable feedback on the manuscript. M.S. acknowledges useful discussions with E. Altman, L. Cugliandolo, and C. Laumann. We acknowledge support from the European Research Council (ERC) under the European Union's Horizon 2020 Research and Innovation Programme Grant Agreement No. 850899. article_number: '062423' article_processing_charge: No article_type: original arxiv: 1 author: - first_name: Raimel A full_name: Medina Ramos, Raimel A id: CE680B90-D85A-11E9-B684-C920E6697425 last_name: Medina Ramos orcid: 0000-0002-5383-2869 - first_name: Maksym full_name: Serbyn, Maksym id: 47809E7E-F248-11E8-B48F-1D18A9856A87 last_name: Serbyn orcid: 0000-0002-2399-5827 citation: ama: Medina Ramos RA, Serbyn M. Duality approach to quantum annealing of the 3-variable exclusive-or satisfiability problem (3-XORSAT). Physical Review A. 2021;104(6). doi:10.1103/physreva.104.062423 apa: Medina Ramos, R. A., & Serbyn, M. (2021). Duality approach to quantum annealing of the 3-variable exclusive-or satisfiability problem (3-XORSAT). Physical Review A. American Physical Society. https://doi.org/10.1103/physreva.104.062423 chicago: Medina Ramos, Raimel A, and Maksym Serbyn. “Duality Approach to Quantum Annealing of the 3-Variable Exclusive-or Satisfiability Problem (3-XORSAT).” Physical Review A. American Physical Society, 2021. https://doi.org/10.1103/physreva.104.062423. ieee: R. A. Medina Ramos and M. Serbyn, “Duality approach to quantum annealing of the 3-variable exclusive-or satisfiability problem (3-XORSAT),” Physical Review A, vol. 104, no. 6. American Physical Society, 2021. ista: Medina Ramos RA, Serbyn M. 2021. Duality approach to quantum annealing of the 3-variable exclusive-or satisfiability problem (3-XORSAT). Physical Review A. 104(6), 062423. mla: Medina Ramos, Raimel A., and Maksym Serbyn. “Duality Approach to Quantum Annealing of the 3-Variable Exclusive-or Satisfiability Problem (3-XORSAT).” Physical Review A, vol. 104, no. 6, 062423, American Physical Society, 2021, doi:10.1103/physreva.104.062423. short: R.A. Medina Ramos, M. Serbyn, Physical Review A 104 (2021). date_created: 2021-12-14T20:46:07Z date_published: 2021-12-14T00:00:00Z date_updated: 2026-10-02T11:36:06Z day: '14' department: - _id: MaSe doi: 10.1103/physreva.104.062423 ec_funded: 1 external_id: arxiv: - '2106.06344' isi: - '000753659200004' fulldoi: https://doi.org/10.1103/physreva.104.062423 intvolume: ' 104' isi: 1 issue: '6' language: - iso: eng main_file_link: - open_access: '1' url: https://arxiv.org/abs/2106.06344 month: '12' oa: 1 oa_version: Preprint project: - _id: 23841C26-32DE-11EA-91FC-C7463DDC885E call_identifier: H2020 grant_number: '850899' name: 'Non-Ergodic Quantum Matter: Universality, Dynamics and Control' publication: Physical Review A publication_identifier: eissn: - 2469-9934 issn: - 2469-9926 publication_status: published publisher: American Physical Society quality_controlled: '1' related_material: record: - id: '17208' relation: dissertation_contains status: public scopus_import: '1' status: public title: Duality approach to quantum annealing of the 3-variable exclusive-or satisfiability problem (3-XORSAT) type: journal_article user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8 volume: 104 year: '2021' ... --- _id: '7553' abstract: - lang: eng text: Normative theories and statistical inference provide complementary approaches for the study of biological systems. A normative theory postulates that organisms have adapted to efficiently solve essential tasks, and proceeds to mathematically work out testable consequences of such optimality; parameters that maximize the hypothesized organismal function can be derived ab initio, without reference to experimental data. In contrast, statistical inference focuses on efficient utilization of data to learn model parameters, without reference to any a priori notion of biological function, utility, or fitness. Traditionally, these two approaches were developed independently and applied separately. Here we unify them in a coherent Bayesian framework that embeds a normative theory into a family of maximum-entropy “optimization priors.” This family defines a smooth interpolation between a data-rich inference regime (characteristic of “bottom-up” statistical models), and a data-limited ab inito prediction regime (characteristic of “top-down” normative theory). We demonstrate the applicability of our framework using data from the visual cortex, and argue that the flexibility it affords is essential to address a number of fundamental challenges relating to inference and prediction in complex, high-dimensional biological problems. acknowledgement: The authors thank Dario Ringach for providing the V1 receptive fields and Olivier Marre for providing the retinal receptive fields. W.M. was funded by the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement no. 754411. M.H. was funded in part by Human Frontiers Science grant no. HFSP RGP0032/2018. article_processing_charge: No author: - first_name: Wiktor F full_name: Mlynarski, Wiktor F id: 358A453A-F248-11E8-B48F-1D18A9856A87 last_name: Mlynarski - first_name: Michal full_name: Hledik, Michal id: 4171253A-F248-11E8-B48F-1D18A9856A87 last_name: Hledik - first_name: Thomas R full_name: Sokolowski, Thomas R id: 3E999752-F248-11E8-B48F-1D18A9856A87 last_name: Sokolowski orcid: 0000-0002-1287-3779 - first_name: Gašper full_name: Tkačik, Gašper id: 3D494DCA-F248-11E8-B48F-1D18A9856A87 last_name: Tkačik orcid: 0000-0002-6699-1455 citation: ama: Mlynarski WF, Hledik M, Sokolowski TR, Tkačik G. Statistical analysis and optimality of neural systems. Neuron. 2021;109(7):1227-1241.e5. doi:10.1016/j.neuron.2021.01.020 apa: Mlynarski, W. F., Hledik, M., Sokolowski, T. R., & Tkačik, G. (2021). Statistical analysis and optimality of neural systems. Neuron. Cell Press. https://doi.org/10.1016/j.neuron.2021.01.020 chicago: Mlynarski, Wiktor F, Michal Hledik, Thomas R Sokolowski, and Gašper Tkačik. “Statistical Analysis and Optimality of Neural Systems.” Neuron. Cell Press, 2021. https://doi.org/10.1016/j.neuron.2021.01.020. ieee: W. F. Mlynarski, M. Hledik, T. R. Sokolowski, and G. Tkačik, “Statistical analysis and optimality of neural systems,” Neuron, vol. 109, no. 7. Cell Press, p. 1227–1241.e5, 2021. ista: Mlynarski WF, Hledik M, Sokolowski TR, Tkačik G. 2021. Statistical analysis and optimality of neural systems. Neuron. 109(7), 1227–1241.e5. mla: Mlynarski, Wiktor F., et al. “Statistical Analysis and Optimality of Neural Systems.” Neuron, vol. 109, no. 7, Cell Press, 2021, p. 1227–1241.e5, doi:10.1016/j.neuron.2021.01.020. short: W.F. Mlynarski, M. Hledik, T.R. Sokolowski, G. Tkačik, Neuron 109 (2021) 1227–1241.e5. corr_author: '1' date_created: 2020-02-28T11:00:12Z date_published: 2021-04-07T00:00:00Z date_updated: 2026-10-02T11:40:30Z day: '07' department: - _id: GaTk doi: 10.1016/j.neuron.2021.01.020 ec_funded: 1 external_id: isi: - '000637809600006' pmid: - '33592180' fulldoi: https://doi.org/10.1016/j.neuron.2021.01.020 intvolume: ' 109' isi: 1 issue: '7' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1101/848374 month: '04' oa: 1 oa_version: Preprint page: 1227-1241.e5 pmid: 1 project: - _id: 260C2330-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '754411' name: ISTplus - Postdoctoral Fellowships publication: Neuron publication_status: published publisher: Cell Press quality_controlled: '1' related_material: link: - description: News on IST Homepage relation: press_release url: https://ist.ac.at/en/news/can-evolution-be-predicted/ record: - id: '15020' relation: dissertation_contains status: public scopus_import: '1' status: public title: Statistical analysis and optimality of neural systems type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 109 year: '2021' ... --- OA_type: free access _id: '9298' abstract: - lang: eng text: 'In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field. ' acknowledgement: This work was supported by the National Institute of General Medical Sciences [GM131919]. Due to space and other limitations, it is not possible to include all other sources of financial support. article_processing_charge: No article_type: review author: - first_name: Daniel J. full_name: Klionsky, Daniel J. last_name: Klionsky - first_name: Amal Kamal full_name: Abdel-Aziz, Amal Kamal last_name: Abdel-Aziz - first_name: Sara full_name: Abdelfatah, Sara last_name: Abdelfatah - first_name: Mahmoud full_name: Abdellatif, Mahmoud last_name: Abdellatif - first_name: Asghar full_name: Abdoli, Asghar last_name: Abdoli - first_name: Steffen full_name: Abel, Steffen last_name: Abel - first_name: Hagai full_name: Abeliovich, Hagai last_name: Abeliovich - first_name: Marie H. full_name: Abildgaard, Marie H. last_name: Abildgaard - first_name: Yakubu Princely full_name: Abudu, Yakubu Princely last_name: Abudu - first_name: Abraham full_name: Acevedo-Arozena, Abraham last_name: Acevedo-Arozena - first_name: Iannis E. full_name: Adamopoulos, Iannis E. last_name: Adamopoulos - first_name: Khosrow full_name: Adeli, Khosrow last_name: Adeli - first_name: Timon E. full_name: Adolph, Timon E. last_name: Adolph - first_name: Annagrazia full_name: Adornetto, Annagrazia last_name: Adornetto - first_name: Elma full_name: Aflaki, Elma last_name: Aflaki - first_name: Galila full_name: Agam, Galila last_name: Agam - first_name: Anupam full_name: Agarwal, Anupam last_name: Agarwal - first_name: Bharat B. full_name: Aggarwal, Bharat B. last_name: Aggarwal - first_name: Maria full_name: Agnello, Maria last_name: Agnello - first_name: Patrizia full_name: Agostinis, Patrizia last_name: Agostinis - first_name: Javed N. full_name: Agrewala, Javed N. last_name: Agrewala - first_name: Alexander full_name: Agrotis, Alexander last_name: Agrotis - first_name: Patricia V. full_name: Aguilar, Patricia V. last_name: Aguilar - first_name: S. Tariq full_name: Ahmad, S. Tariq last_name: Ahmad - first_name: Zubair M. full_name: Ahmed, Zubair M. last_name: Ahmed - first_name: Ulises full_name: Ahumada-Castro, Ulises last_name: Ahumada-Castro - first_name: Sonja full_name: Aits, Sonja last_name: Aits - first_name: Shu full_name: Aizawa, Shu last_name: Aizawa - first_name: Yunus full_name: Akkoc, Yunus last_name: Akkoc - first_name: Tonia full_name: Akoumianaki, Tonia last_name: Akoumianaki - first_name: Hafize Aysin full_name: Akpinar, Hafize Aysin last_name: Akpinar - first_name: Ahmed M. full_name: Al-Abd, Ahmed M. last_name: Al-Abd - first_name: Lina full_name: Al-Akra, Lina last_name: Al-Akra - first_name: Abeer full_name: Al-Gharaibeh, Abeer last_name: Al-Gharaibeh - first_name: Moulay A. full_name: Alaoui-Jamali, Moulay A. last_name: Alaoui-Jamali - first_name: Simon full_name: Alberti, Simon last_name: Alberti - first_name: Elísabet full_name: Alcocer-Gómez, Elísabet last_name: Alcocer-Gómez - first_name: Cristiano full_name: Alessandri, Cristiano last_name: Alessandri - first_name: Muhammad full_name: Ali, Muhammad last_name: Ali - first_name: M. Abdul full_name: Alim Al-Bari, M. Abdul last_name: Alim Al-Bari - first_name: Saeb full_name: Aliwaini, Saeb last_name: Aliwaini - first_name: Javad full_name: Alizadeh, Javad last_name: Alizadeh - first_name: Eugènia full_name: Almacellas, Eugènia last_name: Almacellas - first_name: Alexandru full_name: Almasan, Alexandru last_name: Almasan - first_name: Alicia full_name: Alonso, Alicia last_name: Alonso - first_name: Guillermo D. full_name: Alonso, Guillermo D. last_name: Alonso - first_name: Nihal full_name: Altan-Bonnet, Nihal last_name: Altan-Bonnet - first_name: Dario C. full_name: Altieri, Dario C. last_name: Altieri - first_name: Élida M.C. full_name: Álvarez, Élida M.C. last_name: Álvarez - first_name: Sara full_name: Alves, Sara last_name: Alves - first_name: Cristine full_name: Alves Da Costa, Cristine last_name: Alves Da Costa - first_name: Mazen M. full_name: Alzaharna, Mazen M. last_name: Alzaharna - first_name: Marialaura full_name: Amadio, Marialaura last_name: Amadio - first_name: Consuelo full_name: Amantini, Consuelo last_name: Amantini - first_name: Cristina full_name: Amaral, Cristina last_name: Amaral - first_name: Susanna full_name: Ambrosio, Susanna last_name: Ambrosio - first_name: Amal O. full_name: Amer, Amal O. last_name: Amer - first_name: Veena full_name: Ammanathan, Veena last_name: Ammanathan - first_name: Zhenyi full_name: An, Zhenyi last_name: An - first_name: Stig U. full_name: Andersen, Stig U. last_name: Andersen - first_name: Shaida A. full_name: Andrabi, Shaida A. last_name: Andrabi - first_name: Magaiver full_name: Andrade-Silva, Magaiver last_name: Andrade-Silva - first_name: Allen M. full_name: Andres, Allen M. last_name: Andres - first_name: Sabrina full_name: Angelini, Sabrina last_name: Angelini - first_name: David full_name: Ann, David last_name: Ann - first_name: Uche C. full_name: Anozie, Uche C. last_name: Anozie - first_name: Mohammad Y. full_name: Ansari, Mohammad Y. last_name: Ansari - first_name: Pedro full_name: Antas, Pedro last_name: Antas - first_name: Adam full_name: Antebi, Adam last_name: Antebi - first_name: Zuriñe full_name: Antón, Zuriñe last_name: Antón - first_name: Tahira full_name: Anwar, Tahira last_name: Anwar - first_name: Lionel full_name: Apetoh, Lionel last_name: Apetoh - first_name: Nadezda full_name: Apostolova, Nadezda last_name: Apostolova - first_name: Toshiyuki full_name: Araki, Toshiyuki last_name: Araki - first_name: Yasuhiro full_name: Araki, Yasuhiro last_name: Araki - first_name: Kohei full_name: Arasaki, Kohei last_name: Arasaki - first_name: Wagner L. full_name: Araújo, Wagner L. last_name: Araújo - first_name: Jun full_name: Araya, Jun last_name: Araya - first_name: Catherine full_name: Arden, Catherine last_name: Arden - first_name: Maria Angeles full_name: Arévalo, Maria Angeles last_name: Arévalo - first_name: Sandro full_name: Arguelles, Sandro last_name: Arguelles - first_name: Esperanza full_name: Arias, Esperanza last_name: Arias - first_name: Jyothi full_name: Arikkath, Jyothi last_name: Arikkath - first_name: Hirokazu full_name: Arimoto, Hirokazu last_name: Arimoto - first_name: Aileen R. full_name: Ariosa, Aileen R. last_name: Ariosa - first_name: Darius full_name: Armstrong-James, Darius last_name: Armstrong-James - first_name: Laetitia full_name: Arnauné-Pelloquin, Laetitia last_name: Arnauné-Pelloquin - first_name: Angeles full_name: Aroca, Angeles last_name: Aroca - first_name: Daniela S. full_name: Arroyo, Daniela S. last_name: Arroyo - first_name: Ivica full_name: Arsov, Ivica last_name: Arsov - first_name: Rubén full_name: Artero, Rubén last_name: Artero - first_name: Dalia Maria Lucia full_name: Asaro, Dalia Maria Lucia last_name: Asaro - first_name: Michael full_name: Aschner, Michael last_name: Aschner - first_name: Milad full_name: Ashrafizadeh, Milad last_name: Ashrafizadeh - first_name: Osnat full_name: Ashur-Fabian, Osnat last_name: Ashur-Fabian - first_name: Atanas G. full_name: Atanasov, Atanas G. last_name: Atanasov - first_name: Alicia K. full_name: Au, Alicia K. last_name: Au - first_name: Patrick full_name: Auberger, Patrick last_name: Auberger - first_name: Holger W. full_name: Auner, Holger W. last_name: Auner - first_name: Laure full_name: Aurelian, Laure last_name: Aurelian - first_name: Riccardo full_name: Autelli, Riccardo last_name: Autelli - first_name: Laura full_name: Avagliano, Laura last_name: Avagliano - first_name: Yenniffer full_name: Ávalos, Yenniffer last_name: Ávalos - first_name: Sanja full_name: Aveic, Sanja last_name: Aveic - first_name: Célia Alexandra full_name: Aveleira, Célia Alexandra last_name: Aveleira - first_name: Tamar full_name: Avin-Wittenberg, Tamar last_name: Avin-Wittenberg - first_name: Yucel full_name: Aydin, Yucel last_name: Aydin - first_name: Scott full_name: Ayton, Scott last_name: Ayton - first_name: Srinivas full_name: Ayyadevara, Srinivas last_name: Ayyadevara - first_name: Maria full_name: Azzopardi, Maria last_name: Azzopardi - first_name: Misuzu full_name: Baba, Misuzu last_name: Baba - first_name: Jonathan M. full_name: Backer, Jonathan M. last_name: Backer - first_name: Steven K. full_name: Backues, Steven K. last_name: Backues - first_name: Dong Hun full_name: Bae, Dong Hun last_name: Bae - first_name: Ok Nam full_name: Bae, Ok Nam last_name: Bae - first_name: Soo Han full_name: Bae, Soo Han last_name: Bae - first_name: Eric H. full_name: Baehrecke, Eric H. last_name: Baehrecke - first_name: Ahruem full_name: Baek, Ahruem last_name: Baek - first_name: Seung Hoon full_name: Baek, Seung Hoon last_name: Baek - first_name: Sung Hee full_name: Baek, Sung Hee last_name: Baek - first_name: Giacinto full_name: Bagetta, Giacinto last_name: Bagetta - first_name: Agnieszka full_name: Bagniewska-Zadworna, Agnieszka last_name: Bagniewska-Zadworna - first_name: Hua full_name: Bai, Hua last_name: Bai - first_name: Jie full_name: Bai, Jie last_name: Bai - first_name: Xiyuan full_name: Bai, Xiyuan last_name: Bai - first_name: Yidong full_name: Bai, Yidong last_name: Bai - first_name: Nandadulal full_name: Bairagi, Nandadulal last_name: Bairagi - first_name: Shounak full_name: Baksi, Shounak last_name: Baksi - first_name: Teresa full_name: Balbi, Teresa last_name: Balbi - first_name: Cosima T. full_name: Baldari, Cosima T. last_name: Baldari - first_name: Walter full_name: Balduini, Walter last_name: Balduini - first_name: Andrea full_name: Ballabio, Andrea last_name: Ballabio - first_name: Maria full_name: Ballester, Maria last_name: Ballester - first_name: Salma full_name: Balazadeh, Salma last_name: Balazadeh - first_name: Rena full_name: Balzan, Rena last_name: Balzan - first_name: Rina full_name: Bandopadhyay, Rina last_name: Bandopadhyay - first_name: Sreeparna full_name: Banerjee, Sreeparna last_name: Banerjee - first_name: Sulagna full_name: Banerjee, Sulagna last_name: Banerjee - first_name: Ágnes full_name: Bánréti, Ágnes last_name: Bánréti - first_name: Yan full_name: Bao, Yan last_name: Bao - first_name: Mauricio S. full_name: Baptista, Mauricio S. last_name: Baptista - first_name: Alessandra full_name: Baracca, Alessandra last_name: Baracca - first_name: Cristiana full_name: Barbati, Cristiana last_name: Barbati - first_name: Ariadna full_name: Bargiela, Ariadna last_name: Bargiela - first_name: Daniela full_name: Barilà, Daniela last_name: Barilà - first_name: Peter G. full_name: Barlow, Peter G. last_name: Barlow - first_name: Sami J. full_name: Barmada, Sami J. last_name: Barmada - first_name: Esther full_name: Barreiro, Esther last_name: Barreiro - first_name: George E. full_name: Barreto, George E. last_name: Barreto - first_name: Jiri full_name: Bartek, Jiri last_name: Bartek - first_name: Bonnie full_name: Bartel, Bonnie last_name: Bartel - first_name: Alberto full_name: Bartolome, Alberto last_name: Bartolome - first_name: Gaurav R. full_name: Barve, Gaurav R. last_name: Barve - first_name: Suresh H. full_name: Basagoudanavar, Suresh H. last_name: Basagoudanavar - first_name: Diane C. full_name: Bassham, Diane C. last_name: Bassham - first_name: Robert C. full_name: Bast, Robert C. last_name: Bast - first_name: Alakananda full_name: Basu, Alakananda last_name: Basu - first_name: Henri full_name: Batoko, Henri last_name: Batoko - first_name: Isabella full_name: Batten, Isabella last_name: Batten - first_name: Etienne E. full_name: Baulieu, Etienne E. last_name: Baulieu - first_name: Bradley L. full_name: Baumgarner, Bradley L. last_name: Baumgarner - first_name: Jagadeesh full_name: Bayry, Jagadeesh last_name: Bayry - first_name: Rupert full_name: Beale, Rupert last_name: Beale - first_name: Isabelle full_name: Beau, Isabelle last_name: Beau - first_name: Florian full_name: Beaumatin, Florian last_name: Beaumatin - first_name: Luiz R.G. full_name: Bechara, Luiz R.G. last_name: Bechara - first_name: George R. full_name: Beck, George R. last_name: Beck - first_name: Michael F. full_name: Beers, Michael F. last_name: Beers - first_name: Jakob full_name: Begun, Jakob last_name: Begun - first_name: Christian full_name: Behrends, Christian last_name: Behrends - first_name: Georg M.N. full_name: Behrens, Georg M.N. last_name: Behrens - first_name: Roberto full_name: Bei, Roberto last_name: Bei - first_name: Eloy full_name: Bejarano, Eloy last_name: Bejarano - first_name: Shai full_name: Bel, Shai last_name: Bel - first_name: Christian full_name: Behl, Christian last_name: Behl - first_name: Amine full_name: Belaid, Amine last_name: Belaid - first_name: Naïma full_name: Belgareh-Touzé, Naïma last_name: Belgareh-Touzé - first_name: Cristina full_name: Bellarosa, Cristina last_name: Bellarosa - first_name: Francesca full_name: Belleudi, Francesca last_name: Belleudi - first_name: Melissa full_name: Belló Pérez, Melissa last_name: Belló Pérez - first_name: Raquel full_name: Bello-Morales, Raquel last_name: Bello-Morales - first_name: Jackeline Soares De Oliveira full_name: Beltran, Jackeline Soares De Oliveira last_name: Beltran - first_name: Sebastián full_name: Beltran, Sebastián last_name: Beltran - first_name: Doris Mangiaracina full_name: Benbrook, Doris Mangiaracina last_name: Benbrook - first_name: Mykolas full_name: Bendorius, Mykolas last_name: Bendorius - first_name: Bruno A. full_name: Benitez, Bruno A. last_name: Benitez - first_name: Irene full_name: Benito-Cuesta, Irene last_name: Benito-Cuesta - first_name: Julien full_name: Bensalem, Julien last_name: Bensalem - first_name: Martin W. full_name: Berchtold, Martin W. last_name: Berchtold - first_name: Sabina full_name: Berezowska, Sabina last_name: Berezowska - first_name: Daniele full_name: Bergamaschi, Daniele last_name: Bergamaschi - first_name: Matteo full_name: Bergami, Matteo last_name: Bergami - first_name: Andreas full_name: Bergmann, Andreas last_name: Bergmann - first_name: Laura full_name: Berliocchi, Laura last_name: Berliocchi - first_name: Clarisse full_name: Berlioz-Torrent, Clarisse last_name: Berlioz-Torrent - first_name: Amélie full_name: Bernard, Amélie last_name: Bernard - first_name: Lionel full_name: Berthoux, Lionel last_name: Berthoux - first_name: Cagri G. full_name: Besirli, Cagri G. last_name: Besirli - first_name: Sebastien full_name: Besteiro, Sebastien last_name: Besteiro - first_name: Virginie M. full_name: Betin, Virginie M. last_name: Betin - first_name: Rudi full_name: Beyaert, Rudi last_name: Beyaert - first_name: Jelena S. full_name: Bezbradica, Jelena S. last_name: Bezbradica - first_name: Kiran full_name: Bhaskar, Kiran last_name: Bhaskar - first_name: Ingrid full_name: Bhatia-Kissova, Ingrid last_name: Bhatia-Kissova - first_name: Resham full_name: Bhattacharya, Resham last_name: Bhattacharya - first_name: Sujoy full_name: Bhattacharya, Sujoy last_name: Bhattacharya - first_name: Shalmoli full_name: Bhattacharyya, Shalmoli last_name: Bhattacharyya - first_name: Md Shenuarin full_name: Bhuiyan, Md Shenuarin last_name: Bhuiyan - first_name: Sujit Kumar full_name: Bhutia, Sujit Kumar last_name: Bhutia - first_name: Lanrong full_name: Bi, Lanrong last_name: Bi - first_name: Xiaolin full_name: Bi, Xiaolin last_name: Bi - first_name: Trevor J. full_name: Biden, Trevor J. last_name: Biden - first_name: Krikor full_name: Bijian, Krikor last_name: Bijian - first_name: Viktor A. full_name: Billes, Viktor A. last_name: Billes - first_name: Nadine full_name: Binart, Nadine last_name: Binart - first_name: Claudia full_name: Bincoletto, Claudia last_name: Bincoletto - first_name: Asa B. full_name: Birgisdottir, Asa B. last_name: Birgisdottir - first_name: Geir full_name: Bjorkoy, Geir last_name: Bjorkoy - first_name: Gonzalo full_name: Blanco, Gonzalo last_name: Blanco - first_name: Ana full_name: Blas-Garcia, Ana last_name: Blas-Garcia - first_name: Janusz full_name: Blasiak, Janusz last_name: Blasiak - first_name: Robert full_name: Blomgran, Robert last_name: Blomgran - first_name: Klas full_name: Blomgren, Klas last_name: Blomgren - first_name: Janice S. full_name: Blum, Janice S. last_name: Blum - first_name: Emilio full_name: Boada-Romero, Emilio last_name: Boada-Romero - first_name: Mirta full_name: Boban, Mirta last_name: Boban - first_name: Kathleen full_name: Boesze-Battaglia, Kathleen last_name: Boesze-Battaglia - first_name: Philippe full_name: Boeuf, Philippe last_name: Boeuf - first_name: Barry full_name: Boland, Barry last_name: Boland - first_name: Pascale full_name: Bomont, Pascale last_name: Bomont - first_name: Paolo full_name: Bonaldo, Paolo last_name: Bonaldo - first_name: Srinivasa Reddy full_name: Bonam, Srinivasa Reddy last_name: Bonam - first_name: Laura full_name: Bonfili, Laura last_name: Bonfili - first_name: Juan S. full_name: Bonifacino, Juan S. last_name: Bonifacino - first_name: Brian A. full_name: Boone, Brian A. last_name: Boone - first_name: Martin D. full_name: Bootman, Martin D. last_name: Bootman - first_name: Matteo full_name: Bordi, Matteo last_name: Bordi - first_name: Christoph full_name: Borner, Christoph last_name: Borner - first_name: Beat C. full_name: Bornhauser, Beat C. last_name: Bornhauser - first_name: Gautam full_name: Borthakur, Gautam last_name: Borthakur - first_name: Jürgen full_name: Bosch, Jürgen last_name: Bosch - first_name: Santanu full_name: Bose, Santanu last_name: Bose - first_name: Luis M. full_name: Botana, Luis M. last_name: Botana - first_name: Juan full_name: Botas, Juan last_name: Botas - first_name: Chantal M. full_name: Boulanger, Chantal M. last_name: Boulanger - first_name: Michael E. full_name: Boulton, Michael E. last_name: Boulton - first_name: Mathieu full_name: Bourdenx, Mathieu last_name: Bourdenx - first_name: Benjamin full_name: Bourgeois, Benjamin last_name: Bourgeois - first_name: Nollaig M. full_name: Bourke, Nollaig M. last_name: Bourke - first_name: Guilhem full_name: Bousquet, Guilhem last_name: Bousquet - first_name: Patricia full_name: Boya, Patricia last_name: Boya - first_name: Peter V. full_name: Bozhkov, Peter V. last_name: Bozhkov - first_name: Luiz H.M. full_name: Bozi, Luiz H.M. last_name: Bozi - first_name: Tolga O. full_name: Bozkurt, Tolga O. last_name: Bozkurt - first_name: Doug E. full_name: Brackney, Doug E. last_name: Brackney - first_name: Christian H. full_name: Brandts, Christian H. last_name: Brandts - first_name: Ralf J. full_name: Braun, Ralf J. last_name: Braun - first_name: Gerhard H. full_name: Braus, Gerhard H. last_name: Braus - first_name: Roberto full_name: Bravo-Sagua, Roberto last_name: Bravo-Sagua - first_name: José M. full_name: Bravo-San Pedro, José M. last_name: Bravo-San Pedro - first_name: Patrick full_name: Brest, Patrick last_name: Brest - first_name: Marie Agnès full_name: Bringer, Marie Agnès last_name: Bringer - first_name: Alfredo full_name: Briones-Herrera, Alfredo last_name: Briones-Herrera - first_name: V. Courtney full_name: Broaddus, V. Courtney last_name: Broaddus - first_name: Peter full_name: Brodersen, Peter last_name: Brodersen - first_name: Jeffrey L. full_name: Brodsky, Jeffrey L. last_name: Brodsky - first_name: Steven L. full_name: Brody, Steven L. last_name: Brody - first_name: Paola G. full_name: Bronson, Paola G. last_name: Bronson - first_name: Jeff M. full_name: Bronstein, Jeff M. last_name: Bronstein - first_name: Carolyn N. full_name: Brown, Carolyn N. last_name: Brown - first_name: Rhoderick E. full_name: Brown, Rhoderick E. last_name: Brown - first_name: Patricia C. full_name: Brum, Patricia C. last_name: Brum - first_name: John H. full_name: Brumell, John H. last_name: Brumell - first_name: Nicola full_name: Brunetti-Pierri, Nicola last_name: Brunetti-Pierri - first_name: Daniele full_name: Bruno, Daniele last_name: Bruno - first_name: Robert J. full_name: Bryson-Richardson, Robert J. last_name: Bryson-Richardson - first_name: Cecilia full_name: Bucci, Cecilia last_name: Bucci - first_name: Carmen full_name: Buchrieser, Carmen last_name: Buchrieser - first_name: Marta full_name: Bueno, Marta last_name: Bueno - first_name: Laura Elisa full_name: Buitrago-Molina, Laura Elisa last_name: Buitrago-Molina - first_name: Simone full_name: Buraschi, Simone last_name: Buraschi - first_name: Shilpa full_name: Buch, Shilpa last_name: Buch - first_name: J. Ross full_name: Buchan, J. Ross last_name: Buchan - first_name: Erin M. full_name: Buckingham, Erin M. last_name: Buckingham - first_name: Hikmet full_name: Budak, Hikmet last_name: Budak - first_name: Mauricio full_name: Budini, Mauricio last_name: Budini - first_name: Geert full_name: Bultynck, Geert last_name: Bultynck - first_name: Florin full_name: Burada, Florin last_name: Burada - first_name: Joseph R. full_name: Burgoyne, Joseph R. last_name: Burgoyne - first_name: M. Isabel full_name: Burón, M. Isabel last_name: Burón - first_name: Victor full_name: Bustos, Victor last_name: Bustos - first_name: Sabrina full_name: Büttner, Sabrina last_name: Büttner - first_name: Elena full_name: Butturini, Elena last_name: Butturini - first_name: Aaron full_name: Byrd, Aaron last_name: Byrd - first_name: Isabel full_name: Cabas, Isabel last_name: Cabas - first_name: Sandra full_name: Cabrera-Benitez, Sandra last_name: Cabrera-Benitez - first_name: Ken full_name: Cadwell, Ken last_name: Cadwell - first_name: Jingjing full_name: Cai, Jingjing last_name: Cai - first_name: Lu full_name: Cai, Lu last_name: Cai - first_name: Qian full_name: Cai, Qian last_name: Cai - first_name: Montserrat full_name: Cairó, Montserrat last_name: Cairó - first_name: Jose A. full_name: Calbet, Jose A. last_name: Calbet - first_name: Guy A. full_name: Caldwell, Guy A. last_name: Caldwell - first_name: Kim A. full_name: Caldwell, Kim A. last_name: Caldwell - first_name: Jarrod A. full_name: Call, Jarrod A. last_name: Call - first_name: Riccardo full_name: Calvani, Riccardo last_name: Calvani - first_name: Ana C. full_name: Calvo, Ana C. last_name: Calvo - first_name: Miguel full_name: Calvo-Rubio Barrera, Miguel last_name: Calvo-Rubio Barrera - first_name: Niels O.S. full_name: Camara, Niels O.S. last_name: Camara - first_name: Jacques H. full_name: Camonis, Jacques H. last_name: Camonis - first_name: Nadine full_name: Camougrand, Nadine last_name: Camougrand - first_name: Michelangelo full_name: Campanella, Michelangelo last_name: Campanella - first_name: Edward M. full_name: Campbell, Edward M. last_name: Campbell - first_name: François Xavier full_name: Campbell-Valois, François Xavier last_name: Campbell-Valois - first_name: Silvia full_name: Campello, Silvia last_name: Campello - first_name: Ilaria full_name: Campesi, Ilaria last_name: Campesi - first_name: Juliane C. full_name: Campos, Juliane C. last_name: Campos - first_name: Olivier full_name: Camuzard, Olivier last_name: Camuzard - first_name: Jorge full_name: Cancino, Jorge last_name: Cancino - first_name: Danilo full_name: Candido De Almeida, Danilo last_name: Candido De Almeida - first_name: Laura full_name: Canesi, Laura last_name: Canesi - first_name: Isabella full_name: Caniggia, Isabella last_name: Caniggia - first_name: Barbara full_name: Canonico, Barbara last_name: Canonico - first_name: Carles full_name: Cantí, Carles last_name: Cantí - first_name: Bin full_name: Cao, Bin last_name: Cao - first_name: Michele full_name: Caraglia, Michele last_name: Caraglia - first_name: Beatriz full_name: Caramés, Beatriz last_name: Caramés - first_name: Evie H. full_name: Carchman, Evie H. last_name: Carchman - first_name: Elena full_name: Cardenal-Muñoz, Elena last_name: Cardenal-Muñoz - first_name: Cesar full_name: Cardenas, Cesar last_name: Cardenas - first_name: Luis full_name: Cardenas, Luis last_name: Cardenas - first_name: Sandra M. full_name: Cardoso, Sandra M. last_name: Cardoso - first_name: Jennifer S. full_name: Carew, Jennifer S. last_name: Carew - first_name: Georges F. full_name: Carle, Georges F. last_name: Carle - first_name: Gillian full_name: Carleton, Gillian last_name: Carleton - first_name: Silvia full_name: Carloni, Silvia last_name: Carloni - first_name: Didac full_name: Carmona-Gutierrez, Didac last_name: Carmona-Gutierrez - first_name: Leticia A. full_name: Carneiro, Leticia A. last_name: Carneiro - first_name: Oliana full_name: Carnevali, Oliana last_name: Carnevali - first_name: Julian M. full_name: Carosi, Julian M. last_name: Carosi - first_name: Serena full_name: Carra, Serena last_name: Carra - first_name: Alice full_name: Carrier, Alice last_name: Carrier - first_name: Lucie full_name: Carrier, Lucie last_name: Carrier - first_name: Bernadette full_name: Carroll, Bernadette last_name: Carroll - first_name: A. Brent full_name: Carter, A. Brent last_name: Carter - first_name: Andreia Neves full_name: Carvalho, Andreia Neves last_name: Carvalho - first_name: Magali full_name: Casanova, Magali last_name: Casanova - first_name: Caty full_name: Casas, Caty last_name: Casas - first_name: Josefina full_name: Casas, Josefina last_name: Casas - first_name: Chiara full_name: Cassioli, Chiara last_name: Cassioli - first_name: Eliseo F. full_name: Castillo, Eliseo F. last_name: Castillo - first_name: Karen full_name: Castillo, Karen last_name: Castillo - first_name: Sonia full_name: Castillo-Lluva, Sonia last_name: Castillo-Lluva - first_name: Francesca full_name: Castoldi, Francesca last_name: Castoldi - first_name: Marco full_name: Castori, Marco last_name: Castori - first_name: Ariel F. full_name: Castro, Ariel F. last_name: Castro - first_name: Margarida full_name: Castro-Caldas, Margarida last_name: Castro-Caldas - first_name: Javier full_name: Castro-Hernandez, Javier last_name: Castro-Hernandez - first_name: Susana full_name: Castro-Obregon, Susana last_name: Castro-Obregon - first_name: Sergio D. full_name: Catz, Sergio D. last_name: Catz - first_name: Claudia full_name: Cavadas, Claudia last_name: Cavadas - first_name: Federica full_name: Cavaliere, Federica last_name: Cavaliere - first_name: Gabriella full_name: Cavallini, Gabriella last_name: Cavallini - first_name: Maria full_name: Cavinato, Maria last_name: Cavinato - first_name: Maria L. full_name: Cayuela, Maria L. last_name: Cayuela - first_name: Paula full_name: Cebollada Rica, Paula last_name: Cebollada Rica - first_name: Valentina full_name: Cecarini, Valentina last_name: Cecarini - first_name: Francesco full_name: Cecconi, Francesco last_name: Cecconi - first_name: Marzanna full_name: Cechowska-Pasko, Marzanna last_name: Cechowska-Pasko - first_name: Simone full_name: Cenci, Simone last_name: Cenci - first_name: Victòria full_name: Ceperuelo-Mallafré, Victòria last_name: Ceperuelo-Mallafré - first_name: João J. full_name: Cerqueira, João J. last_name: Cerqueira - first_name: Janete M. full_name: Cerutti, Janete M. last_name: Cerutti - first_name: Davide full_name: Cervia, Davide last_name: Cervia - first_name: Vildan Bozok full_name: Cetintas, Vildan Bozok last_name: Cetintas - first_name: Silvia full_name: Cetrullo, Silvia last_name: Cetrullo - first_name: Han Jung full_name: Chae, Han Jung last_name: Chae - first_name: Andrei S. full_name: Chagin, Andrei S. last_name: Chagin - first_name: Chee Yin full_name: Chai, Chee Yin last_name: Chai - first_name: Gopal full_name: Chakrabarti, Gopal last_name: Chakrabarti - first_name: Oishee full_name: Chakrabarti, Oishee last_name: Chakrabarti - first_name: Tapas full_name: Chakraborty, Tapas last_name: Chakraborty - first_name: Trinad full_name: Chakraborty, Trinad last_name: Chakraborty - first_name: Mounia full_name: Chami, Mounia last_name: Chami - first_name: Georgios full_name: Chamilos, Georgios last_name: Chamilos - first_name: David W. full_name: Chan, David W. last_name: Chan - first_name: Edmond Y.W. full_name: Chan, Edmond Y.W. last_name: Chan - first_name: Edward D. full_name: Chan, Edward D. last_name: Chan - first_name: H. 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first_name: Trude H. full_name: Flo, Trude H. last_name: Flo - first_name: Ida full_name: Florance, Ida last_name: Florance - first_name: Oliver full_name: Florey, Oliver last_name: Florey - first_name: Tullio full_name: Florio, Tullio last_name: Florio - first_name: Erika full_name: Fodor, Erika last_name: Fodor - first_name: Carlo full_name: Follo, Carlo last_name: Follo - first_name: Edward A. full_name: Fon, Edward A. last_name: Fon - first_name: Antonella full_name: Forlino, Antonella last_name: Forlino - first_name: Francesco full_name: Fornai, Francesco last_name: Fornai - first_name: Paola full_name: Fortini, Paola last_name: Fortini - first_name: Anna full_name: Fracassi, Anna last_name: Fracassi - first_name: Alessandro full_name: Fraldi, Alessandro last_name: Fraldi - first_name: Brunella full_name: Franco, Brunella last_name: Franco - first_name: Rodrigo full_name: Franco, Rodrigo last_name: Franco - first_name: Flavia full_name: Franconi, Flavia last_name: Franconi - first_name: Lisa B. full_name: Frankel, Lisa B. last_name: Frankel - 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first_name: Maria Noé full_name: Garcia, Maria Noé last_name: Garcia - first_name: Verónica E. full_name: Garcia, Verónica E. last_name: Garcia - first_name: Francisco full_name: García-Del Portillo, Francisco last_name: García-Del Portillo - first_name: Vega full_name: Garcia-Escudero, Vega last_name: Garcia-Escudero - first_name: Aracely full_name: Garcia-Garcia, Aracely last_name: Garcia-Garcia - first_name: Marina full_name: Garcia-Macia, Marina last_name: Garcia-Macia - first_name: Diana full_name: García-Moreno, Diana last_name: García-Moreno - first_name: Carmen full_name: Garcia-Ruiz, Carmen last_name: Garcia-Ruiz - first_name: Patricia full_name: García-Sanz, Patricia last_name: García-Sanz - first_name: Abhishek D. full_name: Garg, Abhishek D. last_name: Garg - first_name: Ricardo full_name: Gargini, Ricardo last_name: Gargini - first_name: Tina full_name: Garofalo, Tina last_name: Garofalo - first_name: Robert F. full_name: Garry, Robert F. last_name: Garry - first_name: Nils C. full_name: Gassen, Nils C. last_name: Gassen - 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first_name: Julien full_name: Giustiniani, Julien last_name: Giustiniani - first_name: Alexander full_name: Gluschko, Alexander last_name: Gluschko - first_name: Veit full_name: Goder, Veit last_name: Goder - first_name: Alexander full_name: Goginashvili, Alexander last_name: Goginashvili - first_name: Jakub full_name: Golab, Jakub last_name: Golab - first_name: David C. full_name: Goldstone, David C. last_name: Goldstone - first_name: Anna full_name: Golebiewska, Anna last_name: Golebiewska - first_name: Luciana R. full_name: Gomes, Luciana R. last_name: Gomes - first_name: Rodrigo full_name: Gomez, Rodrigo last_name: Gomez - first_name: Rubén full_name: Gómez-Sánchez, Rubén last_name: Gómez-Sánchez - first_name: Maria Catalina full_name: Gomez-Puerto, Maria Catalina last_name: Gomez-Puerto - first_name: Raquel full_name: Gomez-Sintes, Raquel last_name: Gomez-Sintes - first_name: Qingqiu full_name: Gong, Qingqiu last_name: Gong - first_name: Felix M. full_name: Goni, Felix M. last_name: Goni - 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first_name: Illana full_name: Gozes, Illana last_name: Gozes - first_name: Devrim full_name: Gozuacik, Devrim last_name: Gozuacik - first_name: Martin full_name: Graef, Martin last_name: Graef - first_name: Markus H. full_name: Gräler, Markus H. last_name: Gräler - first_name: Veronica full_name: Granatiero, Veronica last_name: Granatiero - first_name: Daniel full_name: Grasso, Daniel last_name: Grasso - first_name: Joshua P. full_name: Gray, Joshua P. last_name: Gray - first_name: Douglas R. full_name: Green, Douglas R. last_name: Green - first_name: Alexander full_name: Greenhough, Alexander last_name: Greenhough - first_name: Stephen L. full_name: Gregory, Stephen L. last_name: Gregory - first_name: Edward F. full_name: Griffin, Edward F. last_name: Griffin - first_name: Mark W. full_name: Grinstaff, Mark W. last_name: Grinstaff - first_name: Frederic full_name: Gros, Frederic last_name: Gros - first_name: Charles full_name: Grose, Charles last_name: Grose - first_name: Angelina S. full_name: Gross, Angelina S. last_name: Gross - 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first_name: Min Goo full_name: Lee, Min Goo last_name: Lee - first_name: Min Jae full_name: Lee, Min Jae last_name: Lee - first_name: Myung Shik full_name: Lee, Myung Shik last_name: Lee - first_name: Sang Yoon full_name: Lee, Sang Yoon last_name: Lee - first_name: Seung Jae full_name: Lee, Seung Jae last_name: Lee - first_name: Stella Y. full_name: Lee, Stella Y. last_name: Lee - first_name: Sung Bae full_name: Lee, Sung Bae last_name: Lee - first_name: Won Hee full_name: Lee, Won Hee last_name: Lee - first_name: Ying Ray full_name: Lee, Ying Ray last_name: Lee - first_name: Yong Ho full_name: Lee, Yong Ho last_name: Lee - first_name: Youngil full_name: Lee, Youngil last_name: Lee - first_name: Christophe full_name: Lefebvre, Christophe last_name: Lefebvre - first_name: Renaud full_name: Legouis, Renaud last_name: Legouis - first_name: Yu L. full_name: Lei, Yu L. last_name: Lei - first_name: Yuchen full_name: Lei, Yuchen last_name: Lei - first_name: Sergey full_name: Leikin, Sergey last_name: Leikin - first_name: Gerd full_name: Leitinger, Gerd last_name: Leitinger - first_name: Leticia full_name: Lemus, Leticia last_name: Lemus - first_name: Shuilong full_name: Leng, Shuilong last_name: Leng - first_name: Olivia full_name: Lenoir, Olivia last_name: Lenoir - first_name: Guido full_name: Lenz, Guido last_name: Lenz - first_name: Heinz Josef full_name: Lenz, Heinz Josef last_name: Lenz - first_name: Paola full_name: Lenzi, Paola last_name: Lenzi - first_name: Yolanda full_name: León, Yolanda last_name: León - first_name: Andréia M. full_name: Leopoldino, Andréia M. last_name: Leopoldino - first_name: Christoph full_name: Leschczyk, Christoph last_name: Leschczyk - first_name: Stina full_name: Leskelä, Stina last_name: Leskelä - first_name: Elisabeth full_name: Letellier, Elisabeth last_name: Letellier - first_name: Chi Ting full_name: Leung, Chi Ting last_name: Leung - first_name: Po Sing full_name: Leung, Po Sing last_name: Leung - first_name: Jeremy S. full_name: Leventhal, Jeremy S. last_name: Leventhal - 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first_name: Sheng full_name: Li, Sheng last_name: Li - first_name: Tiangang full_name: Li, Tiangang last_name: Li - first_name: Wei full_name: Li, Wei last_name: Li - first_name: Wenming full_name: Li, Wenming last_name: Li - first_name: Xue full_name: Li, Xue last_name: Li - first_name: Yi Ping full_name: Li, Yi Ping last_name: Li - first_name: Yuan full_name: Li, Yuan last_name: Li - first_name: Zhiqiang full_name: Li, Zhiqiang last_name: Li - first_name: Zhiyong full_name: Li, Zhiyong last_name: Li - first_name: Zhiyuan full_name: Li, Zhiyuan last_name: Li - first_name: Jiqin full_name: Lian, Jiqin last_name: Lian - first_name: Chengyu full_name: Liang, Chengyu last_name: Liang - first_name: Qiangrong full_name: Liang, Qiangrong last_name: Liang - first_name: Weicheng full_name: Liang, Weicheng last_name: Liang - first_name: Yongheng full_name: Liang, Yongheng last_name: Liang - first_name: Yong Tian full_name: Liang, Yong Tian last_name: Liang - first_name: Guanghong full_name: Liao, Guanghong last_name: Liao - first_name: Lujian full_name: Liao, Lujian last_name: Liao - first_name: Mingzhi full_name: Liao, Mingzhi last_name: Liao - first_name: Yung Feng full_name: Liao, Yung Feng last_name: Liao - first_name: Mariangela full_name: Librizzi, Mariangela last_name: Librizzi - first_name: Pearl P.Y. full_name: Lie, Pearl P.Y. last_name: Lie - first_name: Mary A. full_name: Lilly, Mary A. last_name: Lilly - first_name: Hyunjung J. full_name: Lim, Hyunjung J. last_name: Lim - first_name: Thania R.R. full_name: Lima, Thania R.R. last_name: Lima - first_name: Federica full_name: Limana, Federica last_name: Limana - first_name: Chao full_name: Lin, Chao last_name: Lin - first_name: Chih Wen full_name: Lin, Chih Wen last_name: Lin - first_name: Dar Shong full_name: Lin, Dar Shong last_name: Lin - first_name: Fu Cheng full_name: Lin, Fu Cheng last_name: Lin - first_name: Jiandie D. full_name: Lin, Jiandie D. last_name: Lin - first_name: Kurt M. full_name: Lin, Kurt M. last_name: Lin - first_name: Kwang Huei full_name: Lin, Kwang Huei last_name: Lin - first_name: Liang Tzung full_name: Lin, Liang Tzung last_name: Lin - first_name: Pei Hui full_name: Lin, Pei Hui last_name: Lin - first_name: Qiong full_name: Lin, Qiong last_name: Lin - first_name: Shaofeng full_name: Lin, Shaofeng last_name: Lin - first_name: Su Ju full_name: Lin, Su Ju last_name: Lin - first_name: Wenyu full_name: Lin, Wenyu last_name: Lin - first_name: Xueying full_name: Lin, Xueying last_name: Lin - first_name: Yao Xin full_name: Lin, Yao Xin last_name: Lin - first_name: Yee Shin full_name: Lin, Yee Shin last_name: Lin - first_name: Rafael full_name: Linden, Rafael last_name: Linden - first_name: Paula full_name: Lindner, Paula last_name: Lindner - first_name: Shuo Chien full_name: Ling, Shuo Chien last_name: Ling - first_name: Paul full_name: Lingor, Paul last_name: Lingor - first_name: Amelia K. full_name: Linnemann, Amelia K. last_name: Linnemann - first_name: Yih Cherng full_name: Liou, Yih Cherng last_name: Liou - first_name: Marta M. full_name: Lipinski, Marta M. last_name: Lipinski - first_name: Saška full_name: Lipovšek, Saška last_name: Lipovšek - first_name: Vitor A. full_name: Lira, Vitor A. last_name: Lira - first_name: Natalia full_name: Lisiak, Natalia last_name: Lisiak - first_name: Paloma B. full_name: Liton, Paloma B. last_name: Liton - first_name: Chao full_name: Liu, Chao last_name: Liu - first_name: Ching Hsuan full_name: Liu, Ching Hsuan last_name: Liu - first_name: Chun Feng full_name: Liu, Chun Feng last_name: Liu - first_name: Cui Hua full_name: Liu, Cui Hua last_name: Liu - first_name: Fang full_name: Liu, Fang last_name: Liu - first_name: Hao full_name: Liu, Hao last_name: Liu - first_name: Hsiao Sheng full_name: Liu, Hsiao Sheng last_name: Liu - first_name: Hua Feng full_name: Liu, Hua Feng last_name: Liu - first_name: Huifang full_name: Liu, Huifang last_name: Liu - first_name: Jia full_name: Liu, Jia last_name: Liu - first_name: Jing full_name: Liu, Jing last_name: Liu - first_name: Julia full_name: Liu, Julia last_name: Liu - first_name: Leyuan full_name: Liu, Leyuan last_name: Liu - first_name: Longhua full_name: Liu, Longhua last_name: Liu - first_name: Meilian full_name: Liu, Meilian last_name: Liu - first_name: Qin full_name: Liu, Qin last_name: Liu - first_name: Wei full_name: Liu, Wei last_name: Liu - first_name: Wende full_name: Liu, Wende last_name: Liu - first_name: Xiao Hong full_name: Liu, Xiao Hong last_name: Liu - first_name: Xiaodong full_name: Liu, Xiaodong last_name: Liu - first_name: Xingguo full_name: Liu, Xingguo last_name: Liu - first_name: Xu full_name: Liu, Xu last_name: Liu - first_name: Xuedong full_name: Liu, Xuedong last_name: Liu - first_name: Yanfen full_name: Liu, Yanfen last_name: Liu - first_name: Yang full_name: Liu, Yang last_name: Liu - first_name: Yang full_name: Liu, Yang last_name: Liu - first_name: Yueyang full_name: Liu, Yueyang last_name: Liu - first_name: Yule full_name: Liu, Yule last_name: Liu - first_name: J. 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first_name: José Antonio full_name: López-Guerrero, José Antonio last_name: López-Guerrero - first_name: Ana T. full_name: López-Jiménez, Ana T. last_name: López-Jiménez - first_name: Óscar full_name: López-Pérez, Óscar last_name: López-Pérez - first_name: Israel full_name: López-Valero, Israel last_name: López-Valero - first_name: Magdalena J. full_name: Lorenowicz, Magdalena J. last_name: Lorenowicz - first_name: Mar full_name: Lorente, Mar last_name: Lorente - first_name: Peter full_name: Lorincz, Peter last_name: Lorincz - first_name: Laura full_name: Lossi, Laura last_name: Lossi - first_name: Sophie full_name: Lotersztajn, Sophie last_name: Lotersztajn - first_name: Penny E. full_name: Lovat, Penny E. last_name: Lovat - first_name: Jonathan F. full_name: Lovell, Jonathan F. last_name: Lovell - first_name: Alenka full_name: Lovy, Alenka last_name: Lovy - first_name: Péter full_name: Lőw, Péter last_name: Lőw - first_name: Guang full_name: Lu, Guang last_name: Lu - first_name: Haocheng full_name: Lu, Haocheng last_name: Lu - first_name: Jia Hong full_name: Lu, Jia Hong last_name: Lu - first_name: Jin Jian full_name: Lu, Jin Jian last_name: Lu - first_name: Mengji full_name: Lu, Mengji last_name: Lu - first_name: Shuyan full_name: Lu, Shuyan last_name: Lu - first_name: Alessandro full_name: Luciani, Alessandro last_name: Luciani - first_name: John M. full_name: Lucocq, John M. last_name: Lucocq - first_name: Paula full_name: Ludovico, Paula last_name: Ludovico - first_name: Micah A. full_name: Luftig, Micah A. last_name: Luftig - first_name: Morten full_name: Luhr, Morten last_name: Luhr - first_name: Diego full_name: Luis-Ravelo, Diego last_name: Luis-Ravelo - first_name: Julian J. full_name: Lum, Julian J. last_name: Lum - first_name: Liany full_name: Luna-Dulcey, Liany last_name: Luna-Dulcey - first_name: Anders H. full_name: Lund, Anders H. last_name: Lund - first_name: Viktor K. full_name: Lund, Viktor K. last_name: Lund - first_name: Jan D. full_name: Lünemann, Jan D. last_name: Lünemann - first_name: Patrick full_name: Lüningschrör, Patrick last_name: Lüningschrör - first_name: Honglin full_name: Luo, Honglin last_name: Luo - first_name: Rongcan full_name: Luo, Rongcan last_name: Luo - first_name: Shouqing full_name: Luo, Shouqing last_name: Luo - first_name: Zhi full_name: Luo, Zhi last_name: Luo - first_name: Claudio full_name: Luparello, Claudio last_name: Luparello - first_name: Bernhard full_name: Lüscher, Bernhard last_name: Lüscher - first_name: Luan full_name: Luu, Luan last_name: Luu - first_name: Alex full_name: Lyakhovich, Alex last_name: Lyakhovich - first_name: Konstantin G. full_name: Lyamzaev, Konstantin G. last_name: Lyamzaev - first_name: Alf Håkon full_name: Lystad, Alf Håkon last_name: Lystad - first_name: Lyubomyr full_name: Lytvynchuk, Lyubomyr last_name: Lytvynchuk - first_name: Alvin C. full_name: Ma, Alvin C. last_name: Ma - first_name: Changle full_name: Ma, Changle last_name: Ma - first_name: Mengxiao full_name: Ma, Mengxiao last_name: Ma - first_name: Ning Fang full_name: Ma, Ning Fang last_name: Ma - first_name: Quan Hong full_name: Ma, Quan Hong last_name: Ma - first_name: Xinliang full_name: Ma, Xinliang last_name: Ma - first_name: Yueyun full_name: Ma, Yueyun last_name: Ma - first_name: Zhenyi full_name: Ma, Zhenyi last_name: Ma - first_name: Ormond A. full_name: Macdougald, Ormond A. last_name: Macdougald - first_name: Fernando full_name: Macian, Fernando last_name: Macian - first_name: Gustavo C. full_name: Macintosh, Gustavo C. last_name: Macintosh - first_name: Jeffrey P. full_name: Mackeigan, Jeffrey P. last_name: Mackeigan - first_name: Kay F. full_name: Macleod, Kay F. last_name: Macleod - first_name: Sandra full_name: Maday, Sandra last_name: Maday - first_name: Frank full_name: Madeo, Frank last_name: Madeo - first_name: Muniswamy full_name: Madesh, Muniswamy last_name: Madesh - first_name: Tobias full_name: Madl, Tobias last_name: Madl - first_name: Julio full_name: Madrigal-Matute, Julio last_name: Madrigal-Matute - first_name: Akiko full_name: Maeda, Akiko last_name: Maeda - first_name: Yasuhiro full_name: Maejima, Yasuhiro last_name: Maejima - first_name: Marta full_name: Magarinos, Marta last_name: Magarinos - first_name: Poornima full_name: Mahavadi, Poornima last_name: Mahavadi - first_name: Emiliano full_name: Maiani, Emiliano last_name: Maiani - first_name: Kenneth full_name: Maiese, Kenneth last_name: Maiese - first_name: Panchanan full_name: Maiti, Panchanan last_name: Maiti - first_name: Maria Chiara full_name: Maiuri, Maria Chiara last_name: Maiuri - first_name: Barbara full_name: Majello, Barbara last_name: Majello - first_name: Michael B. full_name: Major, Michael B. last_name: Major - first_name: Elena full_name: Makareeva, Elena last_name: Makareeva - first_name: Fayaz full_name: Malik, Fayaz last_name: Malik - first_name: Karthik full_name: Mallilankaraman, Karthik last_name: Mallilankaraman - first_name: Walter full_name: Malorni, Walter last_name: Malorni - first_name: Alina full_name: Maloyan, Alina last_name: Maloyan - first_name: Najiba full_name: Mammadova, Najiba last_name: Mammadova - first_name: Gene Chi Wai full_name: Man, Gene Chi Wai last_name: Man - first_name: Federico full_name: Manai, Federico last_name: Manai - first_name: Joseph D. full_name: Mancias, Joseph D. last_name: Mancias - first_name: Eva Maria full_name: Mandelkow, Eva Maria last_name: Mandelkow - first_name: Michael A. full_name: Mandell, Michael A. last_name: Mandell - first_name: Angelo A. full_name: Manfredi, Angelo A. last_name: Manfredi - first_name: Masoud H. full_name: Manjili, Masoud H. last_name: Manjili - first_name: Ravi full_name: Manjithaya, Ravi last_name: Manjithaya - first_name: Patricio full_name: Manque, Patricio last_name: Manque - first_name: Bella B. full_name: Manshian, Bella B. last_name: Manshian - first_name: Raquel full_name: Manzano, Raquel last_name: Manzano - first_name: Claudia full_name: Manzoni, Claudia last_name: Manzoni - first_name: Kai full_name: Mao, Kai last_name: Mao - first_name: Cinzia full_name: Marchese, Cinzia last_name: Marchese - first_name: Sandrine full_name: Marchetti, Sandrine last_name: Marchetti - first_name: Anna Maria full_name: Marconi, Anna Maria last_name: Marconi - first_name: Fabrizio full_name: Marcucci, Fabrizio last_name: Marcucci - first_name: Stefania full_name: Mardente, Stefania last_name: Mardente - first_name: Olga A. full_name: Mareninova, Olga A. last_name: Mareninova - first_name: Marta full_name: Margeta, Marta last_name: Margeta - first_name: Muriel full_name: Mari, Muriel last_name: Mari - first_name: Sara full_name: Marinelli, Sara last_name: Marinelli - first_name: Oliviero full_name: Marinelli, Oliviero last_name: Marinelli - first_name: Guillermo full_name: Mariño, Guillermo last_name: Mariño - first_name: Sofia full_name: Mariotto, Sofia last_name: Mariotto - first_name: Richard S. full_name: Marshall, Richard S. last_name: Marshall - first_name: Mark R. full_name: Marten, Mark R. last_name: Marten - first_name: Sascha full_name: Martens, Sascha last_name: Martens - first_name: Alexandre P.J. full_name: Martin, Alexandre P.J. last_name: Martin - first_name: Katie R. full_name: Martin, Katie R. last_name: Martin - first_name: Sara full_name: Martin, Sara last_name: Martin - first_name: Shaun full_name: Martin, Shaun last_name: Martin - first_name: Adrián full_name: Martín-Segura, Adrián last_name: Martín-Segura - first_name: Miguel A. full_name: Martín-Acebes, Miguel A. last_name: Martín-Acebes - first_name: Inmaculada full_name: Martin-Burriel, Inmaculada last_name: Martin-Burriel - first_name: Marcos full_name: Martin-Rincon, Marcos last_name: Martin-Rincon - first_name: Paloma full_name: Martin-Sanz, Paloma last_name: Martin-Sanz - first_name: José A. full_name: Martina, José A. last_name: Martina - first_name: Wim full_name: Martinet, Wim last_name: Martinet - first_name: Aitor full_name: Martinez, Aitor last_name: Martinez - first_name: Ana full_name: Martinez, Ana last_name: Martinez - first_name: Jennifer full_name: Martinez, Jennifer last_name: Martinez - first_name: Moises full_name: Martinez Velazquez, Moises last_name: Martinez Velazquez - first_name: Nuria full_name: Martinez-Lopez, Nuria last_name: Martinez-Lopez - first_name: Marta full_name: Martinez-Vicente, Marta last_name: Martinez-Vicente - first_name: Daniel O. full_name: Martins, Daniel O. last_name: Martins - first_name: Joilson O. full_name: Martins, Joilson O. last_name: Martins - first_name: Waleska K. full_name: Martins, Waleska K. last_name: Martins - first_name: Tania full_name: Martins-Marques, Tania last_name: Martins-Marques - first_name: Emanuele full_name: Marzetti, Emanuele last_name: Marzetti - first_name: Shashank full_name: Masaldan, Shashank last_name: Masaldan - first_name: Celine full_name: Masclaux-Daubresse, Celine last_name: Masclaux-Daubresse - first_name: Douglas G. full_name: Mashek, Douglas G. last_name: Mashek - first_name: Valentina full_name: Massa, Valentina last_name: Massa - first_name: Lourdes full_name: Massieu, Lourdes last_name: Massieu - first_name: Glenn R. full_name: Masson, Glenn R. last_name: Masson - first_name: Laura full_name: Masuelli, Laura last_name: Masuelli - first_name: Anatoliy I. full_name: Masyuk, Anatoliy I. last_name: Masyuk - first_name: Tetyana V. full_name: Masyuk, Tetyana V. last_name: Masyuk - first_name: Paola full_name: Matarrese, Paola last_name: Matarrese - first_name: Ander full_name: Matheu, Ander last_name: Matheu - first_name: Satoaki full_name: Matoba, Satoaki last_name: Matoba - first_name: Sachiko full_name: Matsuzaki, Sachiko last_name: Matsuzaki - first_name: Pamela full_name: Mattar, Pamela last_name: Mattar - first_name: Alessandro full_name: Matte, Alessandro last_name: Matte - first_name: Domenico full_name: Mattoscio, Domenico last_name: Mattoscio - first_name: José L. full_name: Mauriz, José L. last_name: Mauriz - first_name: Mario full_name: Mauthe, Mario last_name: Mauthe - first_name: Caroline full_name: Mauvezin, Caroline last_name: Mauvezin - first_name: Emanual full_name: Maverakis, Emanual last_name: Maverakis - first_name: Paola full_name: Maycotte, Paola last_name: Maycotte - first_name: Johanna full_name: Mayer, Johanna last_name: Mayer - first_name: Gianluigi full_name: Mazzoccoli, Gianluigi last_name: Mazzoccoli - first_name: Cristina full_name: Mazzoni, Cristina last_name: Mazzoni - first_name: Joseph R. full_name: Mazzulli, Joseph R. last_name: Mazzulli - first_name: Nami full_name: Mccarty, Nami last_name: Mccarty - first_name: Christine full_name: Mcdonald, Christine last_name: Mcdonald - first_name: Mitchell R. full_name: Mcgill, Mitchell R. last_name: Mcgill - first_name: Sharon L. full_name: Mckenna, Sharon L. last_name: Mckenna - first_name: Beth Ann full_name: Mclaughlin, Beth Ann last_name: Mclaughlin - first_name: Fionn full_name: Mcloughlin, Fionn last_name: Mcloughlin - first_name: Mark A. full_name: Mcniven, Mark A. last_name: Mcniven - first_name: Thomas G. full_name: Mcwilliams, Thomas G. last_name: Mcwilliams - first_name: Fatima full_name: Mechta-Grigoriou, Fatima last_name: Mechta-Grigoriou - first_name: Tania Catarina full_name: Medeiros, Tania Catarina last_name: Medeiros - first_name: Diego L. full_name: Medina, Diego L. last_name: Medina - first_name: Lynn A. full_name: Megeney, Lynn A. last_name: Megeney - first_name: Klara full_name: Megyeri, Klara last_name: Megyeri - 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first_name: Roberta full_name: Misasi, Roberta last_name: Misasi - first_name: Amit full_name: Misra, Amit last_name: Misra - first_name: Gabriella full_name: Misso, Gabriella last_name: Misso - first_name: Claire full_name: Mitchell, Claire last_name: Mitchell - first_name: Geraldine full_name: Mitou, Geraldine last_name: Mitou - first_name: Tetsuji full_name: Miura, Tetsuji last_name: Miura - first_name: Shigeki full_name: Miyamoto, Shigeki last_name: Miyamoto - first_name: Makoto full_name: Miyazaki, Makoto last_name: Miyazaki - first_name: Mitsunori full_name: Miyazaki, Mitsunori last_name: Miyazaki - first_name: Taiga full_name: Miyazaki, Taiga last_name: Miyazaki - first_name: Keisuke full_name: Miyazawa, Keisuke last_name: Miyazawa - first_name: Noboru full_name: Mizushima, Noboru last_name: Mizushima - first_name: Trine H. full_name: Mogensen, Trine H. last_name: Mogensen - first_name: Baharia full_name: Mograbi, Baharia last_name: Mograbi - first_name: Reza full_name: Mohammadinejad, Reza last_name: Mohammadinejad - 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first_name: Elena full_name: Papaleo, Elena last_name: Papaleo - first_name: Daniel full_name: Papinski, Daniel last_name: Papinski - first_name: Diana full_name: Papp, Diana last_name: Papp - first_name: Eun Chan full_name: Park, Eun Chan last_name: Park - first_name: Hwan Tae full_name: Park, Hwan Tae last_name: Park - first_name: Ji Man full_name: Park, Ji Man last_name: Park - first_name: Jong In full_name: Park, Jong In last_name: Park - first_name: Joon Tae full_name: Park, Joon Tae last_name: Park - first_name: Junsoo full_name: Park, Junsoo last_name: Park - first_name: Sang Chul full_name: Park, Sang Chul last_name: Park - first_name: Sang Youel full_name: Park, Sang Youel last_name: Park - first_name: Abraham H. full_name: Parola, Abraham H. last_name: Parola - first_name: Jan B. full_name: Parys, Jan B. last_name: Parys - first_name: Adrien full_name: Pasquier, Adrien last_name: Pasquier - first_name: Benoit full_name: Pasquier, Benoit last_name: Pasquier - first_name: João F. full_name: Passos, João F. last_name: Passos - first_name: Nunzia full_name: Pastore, Nunzia last_name: Pastore - first_name: Hemal H. full_name: Patel, Hemal H. last_name: Patel - first_name: Daniel full_name: Patschan, Daniel last_name: Patschan - first_name: Sophie full_name: Pattingre, Sophie last_name: Pattingre - first_name: Gustavo full_name: Pedraza-Alva, Gustavo last_name: Pedraza-Alva - first_name: Jose full_name: Pedraza-Chaverri, Jose last_name: Pedraza-Chaverri - first_name: Zully full_name: Pedrozo, Zully last_name: Pedrozo - first_name: Gang full_name: Pei, Gang last_name: Pei - first_name: Jianming full_name: Pei, Jianming last_name: Pei - first_name: Hadas full_name: Peled-Zehavi, Hadas last_name: Peled-Zehavi - first_name: Joaquín M. full_name: Pellegrini, Joaquín M. last_name: Pellegrini - first_name: Joffrey full_name: Pelletier, Joffrey last_name: Pelletier - first_name: Miguel A. full_name: Peñalva, Miguel A. last_name: Peñalva - first_name: Di full_name: Peng, Di last_name: Peng - first_name: Ying full_name: Peng, Ying last_name: Peng - first_name: Fabio full_name: Penna, Fabio last_name: Penna - first_name: Maria full_name: Pennuto, Maria last_name: Pennuto - first_name: Francesca full_name: Pentimalli, Francesca last_name: Pentimalli - first_name: Cláudia M.F. full_name: Pereira, Cláudia M.F. last_name: Pereira - first_name: Gustavo J.S. full_name: Pereira, Gustavo J.S. last_name: Pereira - first_name: Lilian C. full_name: Pereira, Lilian C. last_name: Pereira - first_name: Luis full_name: Pereira De Almeida, Luis last_name: Pereira De Almeida - first_name: Nirma D. full_name: Perera, Nirma D. last_name: Perera - first_name: Ángel full_name: Pérez-Lara, Ángel last_name: Pérez-Lara - first_name: Ana B. full_name: Perez-Oliva, Ana B. last_name: Perez-Oliva - first_name: María Esther full_name: Pérez-Pérez, María Esther last_name: Pérez-Pérez - first_name: Palsamy full_name: Periyasamy, Palsamy last_name: Periyasamy - first_name: Andras full_name: Perl, Andras last_name: Perl - first_name: Cristiana full_name: Perrotta, Cristiana last_name: Perrotta - first_name: Ida full_name: Perrotta, Ida last_name: Perrotta - first_name: Richard G. full_name: Pestell, Richard G. last_name: Pestell - first_name: Morten full_name: Petersen, Morten last_name: Petersen - first_name: Irina full_name: Petrache, Irina last_name: Petrache - first_name: Goran full_name: Petrovski, Goran last_name: Petrovski - first_name: Thorsten full_name: Pfirrmann, Thorsten last_name: Pfirrmann - first_name: Astrid S. full_name: Pfister, Astrid S. last_name: Pfister - first_name: Jennifer A. full_name: Philips, Jennifer A. last_name: Philips - first_name: Huifeng full_name: Pi, Huifeng last_name: Pi - first_name: Anna full_name: Picca, Anna last_name: Picca - first_name: Alicia M. full_name: Pickrell, Alicia M. last_name: Pickrell - first_name: Sandy full_name: Picot, Sandy last_name: Picot - first_name: Giovanna M. full_name: Pierantoni, Giovanna M. last_name: Pierantoni - first_name: Marina full_name: Pierdominici, Marina last_name: Pierdominici - first_name: Philippe full_name: Pierre, Philippe last_name: Pierre - first_name: Valérie full_name: Pierrefite-Carle, Valérie last_name: Pierrefite-Carle - first_name: Karolina full_name: Pierzynowska, Karolina last_name: Pierzynowska - first_name: Federico full_name: Pietrocola, Federico last_name: Pietrocola - first_name: Miroslawa full_name: Pietruczuk, Miroslawa last_name: Pietruczuk - first_name: Claudio full_name: Pignata, Claudio last_name: Pignata - first_name: Felipe X. full_name: Pimentel-Muiños, Felipe X. last_name: Pimentel-Muiños - first_name: Mario full_name: Pinar, Mario last_name: Pinar - first_name: Roberta O. full_name: Pinheiro, Roberta O. last_name: Pinheiro - first_name: Ronit full_name: Pinkas-Kramarski, Ronit last_name: Pinkas-Kramarski - first_name: Paolo full_name: Pinton, Paolo last_name: Pinton - first_name: Karolina full_name: Pircs, Karolina last_name: Pircs - first_name: Sujan full_name: Piya, Sujan last_name: Piya - first_name: Paola full_name: Pizzo, Paola last_name: Pizzo - first_name: Theo S. full_name: Plantinga, Theo S. last_name: Plantinga - first_name: Harald W. full_name: Platta, Harald W. last_name: Platta - first_name: Ainhoa full_name: Plaza-Zabala, Ainhoa last_name: Plaza-Zabala - first_name: Markus full_name: Plomann, Markus last_name: Plomann - first_name: Egor Y. full_name: Plotnikov, Egor Y. last_name: Plotnikov - first_name: Helene full_name: Plun-Favreau, Helene last_name: Plun-Favreau - first_name: Ryszard full_name: Pluta, Ryszard last_name: Pluta - first_name: Roger full_name: Pocock, Roger last_name: Pocock - first_name: Stefanie full_name: Pöggeler, Stefanie last_name: Pöggeler - first_name: Christian full_name: Pohl, Christian last_name: Pohl - first_name: Marc full_name: Poirot, Marc last_name: Poirot - first_name: Angelo full_name: Poletti, Angelo last_name: Poletti - first_name: Marisa full_name: Ponpuak, Marisa last_name: Ponpuak - first_name: Hana full_name: Popelka, Hana last_name: Popelka - first_name: Blagovesta full_name: Popova, Blagovesta last_name: Popova - first_name: Helena full_name: Porta, Helena last_name: Porta - first_name: Soledad full_name: Porte Alcon, Soledad last_name: Porte Alcon - first_name: Eliana full_name: Portilla-Fernandez, Eliana last_name: Portilla-Fernandez - first_name: Martin full_name: Post, Martin last_name: Post - first_name: Malia B. full_name: Potts, Malia B. last_name: Potts - first_name: Joanna full_name: Poulton, Joanna last_name: Poulton - first_name: Ted full_name: Powers, Ted last_name: Powers - first_name: Veena full_name: Prahlad, Veena last_name: Prahlad - first_name: Tomasz K. full_name: Prajsnar, Tomasz K. last_name: Prajsnar - first_name: Domenico full_name: Praticò, Domenico last_name: Praticò - first_name: Rosaria full_name: Prencipe, Rosaria last_name: Prencipe - first_name: Muriel full_name: Priault, Muriel last_name: Priault - first_name: Tassula full_name: Proikas-Cezanne, Tassula last_name: Proikas-Cezanne - first_name: Vasilis J. full_name: Promponas, Vasilis J. last_name: Promponas - first_name: Christopher G. full_name: Proud, Christopher G. last_name: Proud - first_name: Rosa full_name: Puertollano, Rosa last_name: Puertollano - first_name: Luigi full_name: Puglielli, Luigi last_name: Puglielli - first_name: Thomas full_name: Pulinilkunnil, Thomas last_name: Pulinilkunnil - first_name: Deepika full_name: Puri, Deepika last_name: Puri - first_name: Rajat full_name: Puri, Rajat last_name: Puri - first_name: Julien full_name: Puyal, Julien last_name: Puyal - first_name: Xiaopeng full_name: Qi, Xiaopeng last_name: Qi - first_name: Yongmei full_name: Qi, Yongmei last_name: Qi - first_name: Wenbin full_name: Qian, Wenbin last_name: Qian - first_name: Lei full_name: Qiang, Lei last_name: Qiang - first_name: Yu full_name: Qiu, Yu last_name: Qiu - first_name: Joe full_name: Quadrilatero, Joe last_name: Quadrilatero - first_name: Jorge full_name: Quarleri, Jorge last_name: Quarleri - first_name: Nina full_name: Raben, Nina last_name: Raben - first_name: Hannah full_name: Rabinowich, Hannah last_name: Rabinowich - first_name: Debora full_name: Ragona, Debora last_name: Ragona - first_name: Michael J. full_name: Ragusa, Michael J. last_name: Ragusa - first_name: Nader full_name: Rahimi, Nader last_name: Rahimi - first_name: Marveh full_name: Rahmati, Marveh last_name: Rahmati - first_name: Valeria full_name: Raia, Valeria last_name: Raia - first_name: Nuno full_name: Raimundo, Nuno last_name: Raimundo - first_name: Namakkal Soorappan full_name: Rajasekaran, Namakkal Soorappan last_name: Rajasekaran - first_name: Sriganesh full_name: Ramachandra Rao, Sriganesh last_name: Ramachandra Rao - first_name: Abdelhaq full_name: Rami, Abdelhaq last_name: Rami - first_name: Ignacio full_name: Ramírez-Pardo, Ignacio last_name: Ramírez-Pardo - first_name: David B. full_name: Ramsden, David B. last_name: Ramsden - first_name: Felix full_name: Randow, Felix last_name: Randow - first_name: Pundi N. full_name: Rangarajan, Pundi N. last_name: Rangarajan - first_name: Danilo full_name: Ranieri, Danilo last_name: Ranieri - first_name: Hai full_name: Rao, Hai last_name: Rao - first_name: Lang full_name: Rao, Lang last_name: Rao - first_name: Rekha full_name: Rao, Rekha last_name: Rao - first_name: Sumit full_name: Rathore, Sumit last_name: Rathore - first_name: J. Arjuna full_name: Ratnayaka, J. 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Amer full_name: Riazuddin, S. Amer last_name: Riazuddin - first_name: Teresa M. full_name: Ribeiro-Rodrigues, Teresa M. last_name: Ribeiro-Rodrigues - first_name: Jean Ehrland full_name: Ricci, Jean Ehrland last_name: Ricci - first_name: Romeo full_name: Ricci, Romeo last_name: Ricci - first_name: Victoria full_name: Riccio, Victoria last_name: Riccio - first_name: Des R. full_name: Richardson, Des R. last_name: Richardson - first_name: Yasuko full_name: Rikihisa, Yasuko last_name: Rikihisa - first_name: Makarand V. full_name: Risbud, Makarand V. last_name: Risbud - first_name: Ruth M. full_name: Risueño, Ruth M. last_name: Risueño - first_name: Konstantinos full_name: Ritis, Konstantinos last_name: Ritis - first_name: Salvatore full_name: Rizza, Salvatore last_name: Rizza - first_name: Rosario full_name: Rizzuto, Rosario last_name: Rizzuto - first_name: Helen C. full_name: Roberts, Helen C. last_name: Roberts - first_name: Luke D. full_name: Roberts, Luke D. last_name: Roberts - first_name: Katherine J. full_name: Robinson, Katherine J. last_name: Robinson - first_name: Maria Carmela full_name: Roccheri, Maria Carmela last_name: Roccheri - first_name: Stephane full_name: Rocchi, Stephane last_name: Rocchi - first_name: George G. full_name: Rodney, George G. last_name: Rodney - first_name: Tiago full_name: Rodrigues, Tiago last_name: Rodrigues - first_name: Vagner Ramon full_name: Rodrigues Silva, Vagner Ramon last_name: Rodrigues Silva - first_name: Amaia full_name: Rodriguez, Amaia last_name: Rodriguez - first_name: Ruth full_name: Rodriguez-Barrueco, Ruth last_name: Rodriguez-Barrueco - first_name: Nieves full_name: Rodriguez-Henche, Nieves last_name: Rodriguez-Henche - first_name: Humberto full_name: Rodriguez-Rocha, Humberto last_name: Rodriguez-Rocha - first_name: Jeroen full_name: Roelofs, Jeroen last_name: Roelofs - first_name: Robert S. full_name: Rogers, Robert S. last_name: Rogers - first_name: Vladimir V. full_name: Rogov, Vladimir V. last_name: Rogov - first_name: Ana I. full_name: Rojo, Ana I. last_name: Rojo - first_name: Krzysztof full_name: Rolka, Krzysztof last_name: Rolka - first_name: Vanina full_name: Romanello, Vanina last_name: Romanello - first_name: Luigina full_name: Romani, Luigina last_name: Romani - first_name: Alessandra full_name: Romano, Alessandra last_name: Romano - first_name: Patricia S. full_name: Romano, Patricia S. last_name: Romano - first_name: David full_name: Romeo-Guitart, David last_name: Romeo-Guitart - first_name: Luis C. full_name: Romero, Luis C. last_name: Romero - first_name: Montserrat full_name: Romero, Montserrat last_name: Romero - first_name: Joseph C. full_name: Roney, Joseph C. last_name: Roney - first_name: Christopher full_name: Rongo, Christopher last_name: Rongo - first_name: Sante full_name: Roperto, Sante last_name: Roperto - first_name: Mathias T. full_name: Rosenfeldt, Mathias T. last_name: Rosenfeldt - first_name: Philip full_name: Rosenstiel, Philip last_name: Rosenstiel - first_name: Anne G. full_name: Rosenwald, Anne G. last_name: Rosenwald - first_name: Kevin A. full_name: Roth, Kevin A. last_name: Roth - first_name: Lynn full_name: Roth, Lynn last_name: Roth - first_name: Steven full_name: Roth, Steven last_name: Roth - first_name: Kasper M.A. full_name: Rouschop, Kasper M.A. last_name: Rouschop - first_name: Benoit D. full_name: Roussel, Benoit D. last_name: Roussel - first_name: Sophie full_name: Roux, Sophie last_name: Roux - first_name: Patrizia full_name: Rovere-Querini, Patrizia last_name: Rovere-Querini - first_name: Ajit full_name: Roy, Ajit last_name: Roy - first_name: Aurore full_name: Rozieres, Aurore last_name: Rozieres - first_name: Diego full_name: Ruano, Diego last_name: Ruano - first_name: David C. full_name: Rubinsztein, David C. last_name: Rubinsztein - first_name: Maria P. full_name: Rubtsova, Maria P. last_name: Rubtsova - first_name: Klaus full_name: Ruckdeschel, Klaus last_name: Ruckdeschel - first_name: Christoph full_name: Ruckenstuhl, Christoph last_name: Ruckenstuhl - first_name: Emil full_name: Rudolf, Emil last_name: Rudolf - first_name: Rüdiger full_name: Rudolf, Rüdiger last_name: Rudolf - first_name: Alessandra full_name: Ruggieri, Alessandra last_name: Ruggieri - first_name: Avnika Ashok full_name: Ruparelia, Avnika Ashok last_name: Ruparelia - first_name: Paola full_name: Rusmini, Paola last_name: Rusmini - first_name: Ryan R. full_name: Russell, Ryan R. last_name: Russell - first_name: Gian Luigi full_name: Russo, Gian Luigi last_name: Russo - first_name: Maria full_name: Russo, Maria last_name: Russo - first_name: Rossella full_name: Russo, Rossella last_name: Russo - first_name: Oxana O. full_name: Ryabaya, Oxana O. last_name: Ryabaya - first_name: Kevin M. full_name: Ryan, Kevin M. last_name: Ryan - first_name: Kwon Yul full_name: Ryu, Kwon Yul last_name: Ryu - first_name: Maria full_name: Sabater-Arcis, Maria last_name: Sabater-Arcis - first_name: Ulka full_name: Sachdev, Ulka last_name: Sachdev - first_name: Michael full_name: Sacher, Michael last_name: Sacher - first_name: Carsten full_name: Sachse, Carsten last_name: Sachse - first_name: Abhishek full_name: Sadhu, Abhishek last_name: Sadhu - first_name: Junichi full_name: Sadoshima, Junichi last_name: Sadoshima - first_name: Nathaniel full_name: Safren, Nathaniel last_name: Safren - first_name: Paul full_name: Saftig, Paul last_name: Saftig - first_name: Antonia P. full_name: Sagona, Antonia P. last_name: Sagona - first_name: Gaurav full_name: Sahay, Gaurav last_name: Sahay - first_name: Amirhossein full_name: Sahebkar, Amirhossein last_name: Sahebkar - first_name: Mustafa full_name: Sahin, Mustafa last_name: Sahin - first_name: Ozgur full_name: Sahin, Ozgur last_name: Sahin - first_name: Sumit full_name: Sahni, Sumit last_name: Sahni - first_name: Nayuta full_name: Saito, Nayuta last_name: Saito - first_name: Shigeru full_name: Saito, Shigeru last_name: Saito - first_name: Tsunenori full_name: Saito, Tsunenori last_name: Saito - first_name: Ryohei full_name: Sakai, Ryohei last_name: Sakai - first_name: Yasuyoshi full_name: Sakai, Yasuyoshi last_name: Sakai - first_name: Jun Ichi full_name: Sakamaki, Jun Ichi last_name: Sakamaki - first_name: Kalle full_name: Saksela, Kalle last_name: Saksela - first_name: Gloria full_name: Salazar, Gloria last_name: Salazar - first_name: Anna full_name: Salazar-Degracia, Anna last_name: Salazar-Degracia - first_name: Ghasem H. full_name: Salekdeh, Ghasem H. last_name: Salekdeh - first_name: Ashok K. full_name: Saluja, Ashok K. last_name: Saluja - first_name: Belém full_name: Sampaio-Marques, Belém last_name: Sampaio-Marques - first_name: Maria Cecilia full_name: Sanchez, Maria Cecilia last_name: Sanchez - first_name: Jose A. full_name: Sanchez-Alcazar, Jose A. last_name: Sanchez-Alcazar - first_name: Victoria full_name: Sanchez-Vera, Victoria last_name: Sanchez-Vera - first_name: Vanessa full_name: Sancho-Shimizu, Vanessa last_name: Sancho-Shimizu - first_name: J. Thomas full_name: Sanderson, J. 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Matthew full_name: Scaglione, K. 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Tong, Autophagy 17 (2021) 1–382. date_created: 2021-03-28T22:01:44Z date_published: 2021-02-08T00:00:00Z date_updated: 2026-10-05T13:54:55Z day: '08' ddc: - '580' - '570' department: - _id: JiFr doi: 10.1080/15548627.2020.1797280 external_id: isi: - '000636121800001' pmid: - '33634751' fulldoi: https://doi.org/10.1080/15548627.2020.1797280 intvolume: ' 17' isi: 1 issue: '1' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1080/15548627.2020.1797280 month: '02' oa: 1 oa_version: Published Version page: 1-382 pmid: 1 publication: Autophagy publication_identifier: eissn: - 1554-8635 issn: - 1554-8627 publication_status: published publisher: Taylor & Francis quality_controlled: '1' scopus_import: '1' status: public title: Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) type: journal_article user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9 volume: 17 year: '2021' ... --- _id: '12909' article_processing_charge: No author: - first_name: Alois full_name: Schlögl, Alois id: 45BF87EE-F248-11E8-B48F-1D18A9856A87 last_name: Schlögl orcid: 0000-0002-5621-8100 - first_name: Stefano full_name: Elefante, Stefano id: 490F40CE-F248-11E8-B48F-1D18A9856A87 last_name: Elefante - first_name: Andrei full_name: Hornoiu, Andrei id: 77129392-B450-11EA-8745-D4653DDC885E last_name: Hornoiu - first_name: Stephan full_name: Stadlbauer, Stephan id: 4D0BC184-F248-11E8-B48F-1D18A9856A87 last_name: Stadlbauer citation: ama: 'Schlögl A, Elefante S, Hornoiu A, Stadlbauer S. Managing software on a heterogenous HPC cluster. In: ASHPC21 – Austrian-Slovenian HPC Meeting 2021. University of Ljubljana; 2021:5. doi:10.3359/2021hpc' apa: 'Schlögl, A., Elefante, S., Hornoiu, A., & Stadlbauer, S. (2021). Managing software on a heterogenous HPC cluster. In ASHPC21 – Austrian-Slovenian HPC Meeting 2021 (p. 5). Virtual: University of Ljubljana. https://doi.org/10.3359/2021hpc' chicago: Schlögl, Alois, Stefano Elefante, Andrei Hornoiu, and Stephan Stadlbauer. “Managing Software on a Heterogenous HPC Cluster.” In ASHPC21 – Austrian-Slovenian HPC Meeting 2021, 5. University of Ljubljana, 2021. https://doi.org/10.3359/2021hpc. ieee: A. Schlögl, S. Elefante, A. Hornoiu, and S. Stadlbauer, “Managing software on a heterogenous HPC cluster,” in ASHPC21 – Austrian-Slovenian HPC Meeting 2021, Virtual, 2021, p. 5. ista: 'Schlögl A, Elefante S, Hornoiu A, Stadlbauer S. 2021. Managing software on a heterogenous HPC cluster. ASHPC21 – Austrian-Slovenian HPC Meeting 2021. ASHPC: Austrian-Slovenian HPC Meeting, 5.' mla: Schlögl, Alois, et al. “Managing Software on a Heterogenous HPC Cluster.” ASHPC21 – Austrian-Slovenian HPC Meeting 2021, University of Ljubljana, 2021, p. 5, doi:10.3359/2021hpc. short: A. Schlögl, S. Elefante, A. Hornoiu, S. Stadlbauer, in:, ASHPC21 – Austrian-Slovenian HPC Meeting 2021, University of Ljubljana, 2021, p. 5. conference: end_date: 2021-06-02 location: Virtual name: 'ASHPC: Austrian-Slovenian HPC Meeting' start_date: 2021-05-31 corr_author: '1' date_created: 2023-05-05T13:17:36Z date_published: 2021-06-02T00:00:00Z date_updated: 2026-10-14T09:47:31Z day: '02' ddc: - '000' department: - _id: ScienComp doi: 10.3359/2021hpc file: - access_level: open_access checksum: ba73f85858fb9d5737ebc7724646dd45 content_type: application/pdf creator: dernst date_created: 2023-05-16T07:36:34Z date_updated: 2023-05-16T07:36:34Z file_id: '12971' file_name: 2021_ASHPC_Schloegl.pdf file_size: 422761 relation: main_file success: 1 file_date_updated: 2023-05-16T07:36:34Z fulldoi: https://doi.org/10.3359/2021hpc has_accepted_license: '1' language: - iso: eng main_file_link: - open_access: '1' url: https://vsc.ac.at/fileadmin/user_upload/vsc/conferences/ashpc21/BOOKLET_ASHPC21.pdf month: '06' oa: 1 oa_version: Published Version page: '5' publication: ASHPC21 – Austrian-Slovenian HPC Meeting 2021 publication_identifier: isbn: - 978-961-6980-77-7 - 978-961-6133-48-7 publication_status: published publisher: University of Ljubljana status: public title: Managing software on a heterogenous HPC cluster type: conference_abstract user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2021' ... --- _id: '10004' abstract: - lang: eng text: 'Markov chains are the de facto finite-state model for stochastic dynamical systems, and Markov decision processes (MDPs) extend Markov chains by incorporating non-deterministic behaviors. Given an MDP and rewards on states, a classical optimization criterion is the maximal expected total reward where the MDP stops after T steps, which can be computed by a simple dynamic programming algorithm. We consider a natural generalization of the problem where the stopping times can be chosen according to a probability distribution, such that the expected stopping time is T, to optimize the expected total reward. Quite surprisingly we establish inter-reducibility of the expected stopping-time problem for Markov chains with the Positivity problem (which is related to the well-known Skolem problem), for which establishing either decidability or undecidability would be a major breakthrough. Given the hardness of the exact problem, we consider the approximate version of the problem: we show that it can be solved in exponential time for Markov chains and in exponential space for MDPs.' acknowledgement: We are grateful to the anonymous reviewers of LICS 2021 and of a previous version of this paper for insightful comments that helped improving the presentation. This research was partially supported by the grant ERC CoG 863818 (ForM-SMArt). article_processing_charge: No arxiv: 1 author: - first_name: Krishnendu full_name: Chatterjee, Krishnendu id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87 last_name: Chatterjee orcid: 0000-0002-4561-241X - first_name: Laurent full_name: Doyen, Laurent last_name: Doyen citation: ama: 'Chatterjee K, Doyen L. Stochastic processes with expected stopping time. In: Proceedings of the 36th Annual ACM/IEEE Symposium on Logic in Computer Science. IEEE; 2021:1-13. doi:10.1109/LICS52264.2021.9470595' apa: 'Chatterjee, K., & Doyen, L. (2021). Stochastic processes with expected stopping time. In Proceedings of the 36th Annual ACM/IEEE Symposium on Logic in Computer Science (pp. 1–13). Rome, Italy: IEEE. https://doi.org/10.1109/LICS52264.2021.9470595' chicago: Chatterjee, Krishnendu, and Laurent Doyen. “Stochastic Processes with Expected Stopping Time.” In Proceedings of the 36th Annual ACM/IEEE Symposium on Logic in Computer Science, 1–13. IEEE, 2021. https://doi.org/10.1109/LICS52264.2021.9470595. ieee: K. Chatterjee and L. Doyen, “Stochastic processes with expected stopping time,” in Proceedings of the 36th Annual ACM/IEEE Symposium on Logic in Computer Science, Rome, Italy, 2021, pp. 1–13. ista: 'Chatterjee K, Doyen L. 2021. Stochastic processes with expected stopping time. Proceedings of the 36th Annual ACM/IEEE Symposium on Logic in Computer Science. LICS: Logic in Computer Science, 1–13.' mla: Chatterjee, Krishnendu, and Laurent Doyen. “Stochastic Processes with Expected Stopping Time.” Proceedings of the 36th Annual ACM/IEEE Symposium on Logic in Computer Science, IEEE, 2021, pp. 1–13, doi:10.1109/LICS52264.2021.9470595. short: K. Chatterjee, L. Doyen, in:, Proceedings of the 36th Annual ACM/IEEE Symposium on Logic in Computer Science, IEEE, 2021, pp. 1–13. conference: end_date: 2021-07-02 location: Rome, Italy name: 'LICS: Logic in Computer Science' start_date: 2021-06-29 date_created: 2021-09-12T22:01:25Z date_published: 2021-07-07T00:00:00Z date_updated: 2026-10-16T07:57:38Z day: '07' department: - _id: KrCh doi: 10.1109/LICS52264.2021.9470595 ec_funded: 1 external_id: arxiv: - '2104.07278' isi: - '000947350400036' fulldoi: https://doi.org/10.1109/LICS52264.2021.9470595 isi: 1 keyword: - Computer science - Heuristic algorithms - Memory management - Automata - Markov processes - Probability distribution - Complexity theory language: - iso: eng main_file_link: - open_access: '1' url: https://arxiv.org/abs/2104.07278 month: '07' oa: 1 oa_version: Preprint page: 1-13 project: - _id: 0599E47C-7A3F-11EA-A408-12923DDC885E call_identifier: H2020 grant_number: '863818' name: 'Formal Methods for Stochastic Models: Algorithms and Applications' publication: Proceedings of the 36th Annual ACM/IEEE Symposium on Logic in Computer Science publication_identifier: eisbn: - 978-1-6654-4895-6 isbn: - 978-1-6654-4896-3 issn: - 1043-6871 publication_status: published publisher: IEEE quality_controlled: '1' related_material: record: - id: '18630' relation: later_version status: public scopus_import: '1' status: public title: Stochastic processes with expected stopping time type: conference user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2021' ... --- _id: '10408' abstract: - lang: eng text: 'Key trees are often the best solution in terms of transmission cost and storage requirements for managing keys in a setting where a group needs to share a secret key, while being able to efficiently rotate the key material of users (in order to recover from a potential compromise, or to add or remove users). Applications include multicast encryption protocols like LKH (Logical Key Hierarchies) or group messaging like the current IETF proposal TreeKEM. A key tree is a (typically balanced) binary tree, where each node is identified with a key: leaf nodes hold users’ secret keys while the root is the shared group key. For a group of size N, each user just holds log(N) keys (the keys on the path from its leaf to the root) and its entire key material can be rotated by broadcasting 2log(N) ciphertexts (encrypting each fresh key on the path under the keys of its parents). In this work we consider the natural setting where we have many groups with partially overlapping sets of users, and ask if we can find solutions where the cost of rotating a key is better than in the trivial one where we have a separate key tree for each group. We show that in an asymptotic setting (where the number m of groups is fixed while the number N of users grows) there exist more general key graphs whose cost converges to the cost of a single group, thus saving a factor linear in the number of groups over the trivial solution. As our asymptotic “solution” converges very slowly and performs poorly on concrete examples, we propose an algorithm that uses a natural heuristic to compute a key graph for any given group structure. Our algorithm combines two greedy algorithms, and is thus very efficient: it first converts the group structure into a “lattice graph”, which is then turned into a key graph by repeatedly applying the algorithm for constructing a Huffman code. To better understand how far our proposal is from an optimal solution, we prove lower bounds on the update cost of continuous group-key agreement and multicast encryption in a symbolic model admitting (asymmetric) encryption, pseudorandom generators, and secret sharing as building blocks.' acknowledgement: B. Auerbach, M.A. Baig and K. Pietrzak—received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (682815 - TOCNeT); Karen Klein was supported in part by ERC CoG grant 724307 and conducted part of this work at IST Austria, funded by the ERC under the European Union’s Horizon 2020 research and innovation programme (682815 - TOCNeT); Guillermo Pascual-Perez was funded by the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 665385; Michael Walter conducted part of this work at IST Austria, funded by the ERC under the European Union’s Horizon 2020 research and innovation programme (682815 - TOCNeT). alternative_title: - LNCS article_processing_charge: No author: - first_name: Joel F full_name: Alwen, Joel F id: 2A8DFA8C-F248-11E8-B48F-1D18A9856A87 last_name: Alwen - first_name: Benedikt full_name: Auerbach, Benedikt id: D33D2B18-E445-11E9-ABB7-15F4E5697425 last_name: Auerbach orcid: 0000-0002-7553-6606 - first_name: Mirza Ahad full_name: Baig, Mirza Ahad id: 3EDE6DE4-AA5A-11E9-986D-341CE6697425 last_name: Baig - first_name: Miguel full_name: Cueto Noval, Miguel id: ffc563a3-f6e0-11ea-865d-e3cce03d17cc last_name: Cueto Noval orcid: 0000-0002-2505-4246 - first_name: Karen full_name: Klein, Karen id: 3E83A2F8-F248-11E8-B48F-1D18A9856A87 last_name: Klein - first_name: Guillermo full_name: Pascual Perez, Guillermo id: 2D7ABD02-F248-11E8-B48F-1D18A9856A87 last_name: Pascual Perez orcid: 0000-0001-8630-415X - first_name: Krzysztof Z full_name: Pietrzak, Krzysztof Z id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87 last_name: Pietrzak orcid: 0000-0002-9139-1654 - first_name: Michael full_name: Walter, Michael id: 488F98B0-F248-11E8-B48F-1D18A9856A87 last_name: Walter orcid: 0000-0003-3186-2482 citation: ama: 'Alwen JF, Auerbach B, Baig MA, et al. Grafting key trees: Efficient key management for overlapping groups. In: 19th International Conference. Vol 13044. Springer Nature; 2021:222-253. doi:10.1007/978-3-030-90456-2_8' apa: 'Alwen, J. F., Auerbach, B., Baig, M. A., Cueto Noval, M., Klein, K., Pascual Perez, G., … Walter, M. (2021). Grafting key trees: Efficient key management for overlapping groups. In 19th International Conference (Vol. 13044, pp. 222–253). Raleigh, NC, United States: Springer Nature. https://doi.org/10.1007/978-3-030-90456-2_8' chicago: 'Alwen, Joel F, Benedikt Auerbach, Mirza Ahad Baig, Miguel Cueto Noval, Karen Klein, Guillermo Pascual Perez, Krzysztof Z Pietrzak, and Michael Walter. “Grafting Key Trees: Efficient Key Management for Overlapping Groups.” In 19th International Conference, 13044:222–53. Springer Nature, 2021. https://doi.org/10.1007/978-3-030-90456-2_8.' ieee: 'J. F. Alwen et al., “Grafting key trees: Efficient key management for overlapping groups,” in 19th International Conference, Raleigh, NC, United States, 2021, vol. 13044, pp. 222–253.' ista: 'Alwen JF, Auerbach B, Baig MA, Cueto Noval M, Klein K, Pascual Perez G, Pietrzak KZ, Walter M. 2021. Grafting key trees: Efficient key management for overlapping groups. 19th International Conference. TCC: Theory of Cryptography, LNCS, vol. 13044, 222–253.' mla: 'Alwen, Joel F., et al. “Grafting Key Trees: Efficient Key Management for Overlapping Groups.” 19th International Conference, vol. 13044, Springer Nature, 2021, pp. 222–53, doi:10.1007/978-3-030-90456-2_8.' short: J.F. Alwen, B. Auerbach, M.A. Baig, M. Cueto Noval, K. Klein, G. Pascual Perez, K.Z. Pietrzak, M. Walter, in:, 19th International Conference, Springer Nature, 2021, pp. 222–253. conference: end_date: 2021-11-11 location: Raleigh, NC, United States name: 'TCC: Theory of Cryptography' start_date: 2021-11-08 date_created: 2021-12-05T23:01:42Z date_published: 2021-11-04T00:00:00Z date_updated: 2026-10-16T08:11:07Z day: '04' department: - _id: KrPi doi: 10.1007/978-3-030-90456-2_8 ec_funded: 1 external_id: isi: - '000728363700008' fulldoi: https://doi.org/10.1007/978-3-030-90456-2_8 intvolume: ' 13044' isi: 1 language: - iso: eng main_file_link: - open_access: '1' url: https://eprint.iacr.org/2021/1158 month: '11' oa: 1 oa_version: Preprint page: 222-253 project: - _id: 258AA5B2-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '682815' name: Teaching Old Crypto New Tricks - _id: 2564DBCA-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '665385' name: International IST Doctoral Program publication: 19th International Conference publication_identifier: eisbn: - 978-3-030-90456-2 eissn: - 1611-3349 isbn: - 9-783-0309-0455-5 issn: - 0302-9743 publication_status: published publisher: Springer Nature quality_controlled: '1' related_material: record: - id: '18088' relation: dissertation_contains status: public scopus_import: '1' status: public title: 'Grafting key trees: Efficient key management for overlapping groups' type: conference user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8 volume: 13044 year: '2021' ... --- _id: '10049' abstract: - lang: eng text: While messaging systems with strong security guarantees are widely used in practice, designing a protocol that scales efficiently to large groups and enjoys similar security guarantees remains largely open. The two existing proposals to date are ART (Cohn-Gordon et al., CCS18) and TreeKEM (IETF, The Messaging Layer Security Protocol, draft). TreeKEM is the currently considered candidate by the IETF MLS working group, but dynamic group operations (i.e. adding and removing users) can cause efficiency issues. In this paper we formalize and analyze a variant of TreeKEM which we term Tainted TreeKEM (TTKEM for short). The basic idea underlying TTKEM was suggested by Millican (MLS mailing list, February 2018). This version is more efficient than TreeKEM for some natural distributions of group operations, we quantify this through simulations.Our second contribution is two security proofs for TTKEM which establish post compromise and forward secrecy even against adaptive attackers. The security loss (to the underlying PKE) in the Random Oracle Model is a polynomial factor, and a quasipolynomial one in the Standard Model. Our proofs can be adapted to TreeKEM as well. Before our work no security proof for any TreeKEM-like protocol establishing tight security against an adversary who can adaptively choose the sequence of operations was known. We also are the first to prove (or even formalize) active security where the server can arbitrarily deviate from the protocol specification. Proving fully active security – where also the users can arbitrarily deviate – remains open. acknowledgement: The first three authors contributed equally to this work. Funded by the European Research Council (ERC) under the European Union’s Horizon2020 research and innovation programme (682815-TOCNeT). Funded by the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No.665385. article_processing_charge: No author: - first_name: Karen full_name: Klein, Karen id: 3E83A2F8-F248-11E8-B48F-1D18A9856A87 last_name: Klein - first_name: Guillermo full_name: Pascual Perez, Guillermo id: 2D7ABD02-F248-11E8-B48F-1D18A9856A87 last_name: Pascual Perez orcid: 0000-0001-8630-415X - first_name: Michael full_name: Walter, Michael id: 488F98B0-F248-11E8-B48F-1D18A9856A87 last_name: Walter orcid: 0000-0003-3186-2482 - first_name: Chethan full_name: Kamath Hosdurg, Chethan id: 4BD3F30E-F248-11E8-B48F-1D18A9856A87 last_name: Kamath Hosdurg orcid: 0009-0006-6812-7317 - first_name: Margarita full_name: Capretto, Margarita last_name: Capretto - first_name: Miguel full_name: Cueto Noval, Miguel id: ffc563a3-f6e0-11ea-865d-e3cce03d17cc last_name: Cueto Noval orcid: 0000-0002-2505-4246 - first_name: Ilia full_name: Markov, Ilia id: D0CF4148-C985-11E9-8066-0BDEE5697425 last_name: Markov - first_name: Michelle X full_name: Yeo, Michelle X id: 2D82B818-F248-11E8-B48F-1D18A9856A87 last_name: Yeo orcid: 0009-0001-3676-4809 - first_name: Joel F full_name: Alwen, Joel F id: 2A8DFA8C-F248-11E8-B48F-1D18A9856A87 last_name: Alwen - first_name: Krzysztof Z full_name: Pietrzak, Krzysztof Z id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87 last_name: Pietrzak orcid: 0000-0002-9139-1654 citation: ama: 'Klein K, Pascual Perez G, Walter M, et al. Keep the dirt: tainted TreeKEM, adaptively and actively secure continuous group key agreement. In: 2021 IEEE Symposium on Security and Privacy . IEEE; 2021:268-284. doi:10.1109/sp40001.2021.00035' apa: 'Klein, K., Pascual Perez, G., Walter, M., Kamath Hosdurg, C., Capretto, M., Cueto Noval, M., … Pietrzak, K. Z. (2021). Keep the dirt: tainted TreeKEM, adaptively and actively secure continuous group key agreement. In 2021 IEEE Symposium on Security and Privacy (pp. 268–284). San Francisco, CA, United States: IEEE. https://doi.org/10.1109/sp40001.2021.00035' chicago: 'Klein, Karen, Guillermo Pascual Perez, Michael Walter, Chethan Kamath Hosdurg, Margarita Capretto, Miguel Cueto Noval, Ilia Markov, Michelle X Yeo, Joel F Alwen, and Krzysztof Z Pietrzak. “Keep the Dirt: Tainted TreeKEM, Adaptively and Actively Secure Continuous Group Key Agreement.” In 2021 IEEE Symposium on Security and Privacy , 268–84. IEEE, 2021. https://doi.org/10.1109/sp40001.2021.00035.' ieee: 'K. Klein et al., “Keep the dirt: tainted TreeKEM, adaptively and actively secure continuous group key agreement,” in 2021 IEEE Symposium on Security and Privacy , San Francisco, CA, United States, 2021, pp. 268–284.' ista: 'Klein K, Pascual Perez G, Walter M, Kamath Hosdurg C, Capretto M, Cueto Noval M, Markov I, Yeo MX, Alwen JF, Pietrzak KZ. 2021. Keep the dirt: tainted TreeKEM, adaptively and actively secure continuous group key agreement. 2021 IEEE Symposium on Security and Privacy . SP: Symposium on Security and Privacy, 268–284.' mla: 'Klein, Karen, et al. “Keep the Dirt: Tainted TreeKEM, Adaptively and Actively Secure Continuous Group Key Agreement.” 2021 IEEE Symposium on Security and Privacy , IEEE, 2021, pp. 268–84, doi:10.1109/sp40001.2021.00035.' short: K. Klein, G. Pascual Perez, M. Walter, C. Kamath Hosdurg, M. Capretto, M. Cueto Noval, I. Markov, M.X. Yeo, J.F. Alwen, K.Z. Pietrzak, in:, 2021 IEEE Symposium on Security and Privacy , IEEE, 2021, pp. 268–284. conference: end_date: 2021-05-27 location: San Francisco, CA, United States name: 'SP: Symposium on Security and Privacy' start_date: 2021-05-24 corr_author: '1' date_created: 2021-09-27T13:46:27Z date_published: 2021-08-26T00:00:00Z date_updated: 2026-10-16T08:11:07Z day: '26' department: - _id: KrPi - _id: DaAl doi: 10.1109/sp40001.2021.00035 ec_funded: 1 external_id: isi: - '001316065000016' fulldoi: https://doi.org/10.1109/sp40001.2021.00035 isi: 1 language: - iso: eng main_file_link: - open_access: '1' url: https://eprint.iacr.org/2019/1489 month: '08' oa: 1 oa_version: Preprint page: 268-284 project: - _id: 2564DBCA-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '665385' name: International IST Doctoral Program - _id: 258AA5B2-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '682815' name: Teaching Old Crypto New Tricks publication: '2021 IEEE Symposium on Security and Privacy ' publication_status: published publisher: IEEE quality_controlled: '1' related_material: record: - id: '10035' relation: dissertation_contains status: public - id: '18088' relation: dissertation_contains status: public scopus_import: '1' status: public title: 'Keep the dirt: tainted TreeKEM, adaptively and actively secure continuous group key agreement' type: conference user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 year: '2021' ... --- _id: '8602' abstract: - lang: eng text: Collective cell migration offers a rich field of study for non-equilibrium physics and cellular biology, revealing phenomena such as glassy dynamics, pattern formation and active turbulence. However, how mechanical and chemical signalling are integrated at the cellular level to give rise to such collective behaviours remains unclear. We address this by focusing on the highly conserved phenomenon of spatiotemporal waves of density and extracellular signal-regulated kinase (ERK) activation, which appear both in vitro and in vivo during collective cell migration and wound healing. First, we propose a biophysical theory, backed by mechanical and optogenetic perturbation experiments, showing that patterns can be quantitatively explained by a mechanochemical coupling between active cellular tensions and the mechanosensitive ERK pathway. Next, we demonstrate how this biophysical mechanism can robustly induce long-ranged order and migration in a desired orientation, and we determine the theoretically optimal wavelength and period for inducing maximal migration towards free edges, which fits well with experimentally observed dynamics. We thereby provide a bridge between the biophysical origin of spatiotemporal instabilities and the design principles of robust and efficient long-ranged migration. acknowledgement: We would like to thank G. Tkacik and all of the members of the Hannezo and Hirashima groups for useful discussions, X. Trepat for help on traction force microscopy and M. Matsuda for use of the lab facility. E.H. acknowledges grants from the Austrian Science Fund (FWF) (P 31639) and the European Research Council (851288). T.H. acknowledges a grant from JST, PRESTO (JPMJPR1949). This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement no. 665385 (to D.B.), from JSPS KAKENHI grant no. 17J02107 (to N.H.) and from the SPIRITS 2018 of Kyoto University (to E.H. and T.H.). article_processing_charge: No article_type: original author: - first_name: Daniel R full_name: Boocock, Daniel R id: 453AF628-F248-11E8-B48F-1D18A9856A87 last_name: Boocock orcid: 0000-0002-1585-2631 - first_name: Naoya full_name: Hino, Naoya last_name: Hino - first_name: Natalia full_name: Ruzickova, Natalia id: D2761128-D73D-11E9-A1BF-BA0DE6697425 last_name: Ruzickova - first_name: Tsuyoshi full_name: Hirashima, Tsuyoshi last_name: Hirashima - first_name: Edouard B full_name: Hannezo, Edouard B id: 3A9DB764-F248-11E8-B48F-1D18A9856A87 last_name: Hannezo orcid: 0000-0001-6005-1561 citation: ama: Boocock DR, Hino N, Ruzickova N, Hirashima T, Hannezo EB. Theory of mechanochemical patterning and optimal migration in cell monolayers. Nature Physics. 2021;17:267-274. doi:10.1038/s41567-020-01037-7 apa: Boocock, D. R., Hino, N., Ruzickova, N., Hirashima, T., & Hannezo, E. B. (2021). Theory of mechanochemical patterning and optimal migration in cell monolayers. Nature Physics. Springer Nature. https://doi.org/10.1038/s41567-020-01037-7 chicago: Boocock, Daniel R, Naoya Hino, Natalia Ruzickova, Tsuyoshi Hirashima, and Edouard B Hannezo. “Theory of Mechanochemical Patterning and Optimal Migration in Cell Monolayers.” Nature Physics. Springer Nature, 2021. https://doi.org/10.1038/s41567-020-01037-7. ieee: D. R. Boocock, N. Hino, N. Ruzickova, T. Hirashima, and E. B. Hannezo, “Theory of mechanochemical patterning and optimal migration in cell monolayers,” Nature Physics, vol. 17. Springer Nature, pp. 267–274, 2021. ista: Boocock DR, Hino N, Ruzickova N, Hirashima T, Hannezo EB. 2021. Theory of mechanochemical patterning and optimal migration in cell monolayers. Nature Physics. 17, 267–274. mla: Boocock, Daniel R., et al. “Theory of Mechanochemical Patterning and Optimal Migration in Cell Monolayers.” Nature Physics, vol. 17, Springer Nature, 2021, pp. 267–74, doi:10.1038/s41567-020-01037-7. short: D.R. Boocock, N. Hino, N. Ruzickova, T. Hirashima, E.B. Hannezo, Nature Physics 17 (2021) 267–274. corr_author: '1' date_created: 2020-10-04T22:01:37Z date_published: 2021-02-01T00:00:00Z date_updated: 2026-11-12T23:30:06Z day: '01' department: - _id: EdHa doi: 10.1038/s41567-020-01037-7 ec_funded: 1 external_id: isi: - '000573519500002' fulldoi: https://doi.org/10.1038/s41567-020-01037-7 intvolume: ' 17' isi: 1 language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1101/2020.05.15.096479 month: '02' oa: 1 oa_version: Preprint page: 267-274 project: - _id: 268294B6-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: P31639 name: Active mechano-chemical description of the cell cytoskeleton - _id: 05943252-7A3F-11EA-A408-12923DDC885E call_identifier: H2020 grant_number: '851288' name: Design Principles of Branching Morphogenesis - _id: 2564DBCA-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '665385' name: International IST Doctoral Program publication: Nature Physics publication_identifier: eissn: - 1745-2481 issn: - 1745-2473 publication_status: published publisher: Springer Nature quality_controlled: '1' related_material: link: - description: News on IST Homepage relation: press_release url: https://ist.ac.at/en/news/wound-healing-waves/ record: - id: '12964' relation: dissertation_contains status: public scopus_import: '1' status: public title: Theory of mechanochemical patterning and optimal migration in cell monolayers type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 17 year: '2021' ... --- _id: '9817' abstract: - lang: eng text: Elastic bending of initially flat slender elements allows the realization and economic fabrication of intriguing curved shapes. In this work, we derive an intuitive but rigorous geometric characterization of the design space of plane elastic rods with variable stiffness. It enables designers to determine which shapes are physically viable with active bending by visual inspection alone. Building on these insights, we propose a method for efficiently designing the geometry of a flat elastic rod that realizes a target equilibrium curve, which only requires solving a linear program. We implement this method in an interactive computational design tool that gives feedback about the feasibility of a design, and computes the geometry of the structural elements necessary to realize it within an instant. The tool also offers an iterative optimization routine that improves the fabricability of a model while modifying it as little as possible. In addition, we use our geometric characterization to derive an algorithm for analyzing and recovering the stability of elastic curves that would otherwise snap out of their unstable equilibrium shapes by buckling. We show the efficacy of our approach by designing and manufacturing several physical models that are assembled from flat elements. acknowledgement: "We thank the anonymous reviewers for their generous feedback, and Michal Piovarči for his help in producing the supplemental video. This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 715767).\r\n" article_number: '126' article_processing_charge: No article_type: original author: - first_name: Christian full_name: Hafner, Christian id: 400429CC-F248-11E8-B48F-1D18A9856A87 last_name: Hafner - first_name: Bernd full_name: Bickel, Bernd id: 49876194-F248-11E8-B48F-1D18A9856A87 last_name: Bickel orcid: 0000-0001-6511-9385 citation: ama: Hafner C, Bickel B. The design space of plane elastic curves. ACM Transactions on Graphics. 2021;40(4). doi:10.1145/3450626.3459800 apa: 'Hafner, C., & Bickel, B. (2021). The design space of plane elastic curves. ACM Transactions on Graphics. Virtual: Association for Computing Machinery. https://doi.org/10.1145/3450626.3459800' chicago: Hafner, Christian, and Bernd Bickel. “The Design Space of Plane Elastic Curves.” ACM Transactions on Graphics. Association for Computing Machinery, 2021. https://doi.org/10.1145/3450626.3459800. ieee: C. Hafner and B. Bickel, “The design space of plane elastic curves,” ACM Transactions on Graphics, vol. 40, no. 4. Association for Computing Machinery, 2021. ista: Hafner C, Bickel B. 2021. The design space of plane elastic curves. ACM Transactions on Graphics. 40(4), 126. mla: Hafner, Christian, and Bernd Bickel. “The Design Space of Plane Elastic Curves.” ACM Transactions on Graphics, vol. 40, no. 4, 126, Association for Computing Machinery, 2021, doi:10.1145/3450626.3459800. short: C. Hafner, B. Bickel, ACM Transactions on Graphics 40 (2021). conference: end_date: 2021-08-13 location: Virtual name: 'SIGGRAF: Special Interest Group on Computer Graphics and Interactive Techniques' start_date: 2021-08-09 date_created: 2021-08-08T22:01:26Z date_published: 2021-07-19T00:00:00Z date_updated: 2026-11-12T23:30:07Z day: '19' ddc: - '516' department: - _id: BeBi doi: 10.1145/3450626.3459800 ec_funded: 1 external_id: isi: - '000674930900091' file: - access_level: open_access checksum: 7e5d08ce46b0451b3102eacd3d00f85f content_type: application/pdf creator: chafner date_created: 2021-10-18T10:42:15Z date_updated: 2021-10-18T10:42:15Z file_id: '10150' file_name: elastic-curves-paper.pdf file_size: 17064290 relation: main_file success: 1 - access_level: open_access checksum: 0088643478be7c01a703b5b10767348f content_type: application/pdf creator: chafner date_created: 2021-10-18T10:42:22Z date_updated: 2021-10-18T10:42:22Z file_id: '10151' file_name: elastic-curves-supp.pdf file_size: 547156 relation: supplementary_material file_date_updated: 2021-10-18T10:42:22Z fulldoi: https://doi.org/10.1145/3450626.3459800 has_accepted_license: '1' intvolume: ' 40' isi: 1 issue: '4' keyword: - Computing methodologies - shape modeling - modeling and simulation - theory of computation - computational geometry - mathematics of computing - mathematical optimization language: - iso: eng month: '07' oa: 1 oa_version: Published Version project: - _id: 24F9549A-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '715767' name: 'MATERIALIZABLE: Intelligent fabrication-oriented Computational Design and Modeling' publication: ACM Transactions on Graphics publication_identifier: eissn: - 1557-7368 issn: - 0730-0301 publication_status: published publisher: Association for Computing Machinery quality_controlled: '1' related_material: link: - description: News on IST Website relation: press_release url: https://ist.ac.at/en/news/designing-with-elastic-structures/ record: - id: '12897' relation: dissertation_contains status: public scopus_import: '1' status: public title: The design space of plane elastic curves tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8 volume: 40 year: '2021' ... --- _id: '8966' abstract: - lang: eng text: During development, a single cell is transformed into a highly complex organism through progressive cell division, specification and rearrangement. An important prerequisite for the emergence of patterns within the developing organism is to establish asymmetries at various scales, ranging from individual cells to the entire embryo, eventually giving rise to the different body structures. This becomes especially apparent during gastrulation, when the earliest major lineage restriction events lead to the formation of the different germ layers. Traditionally, the unfolding of the developmental program from symmetry breaking to germ layer formation has been studied by dissecting the contributions of different signaling pathways and cellular rearrangements in the in vivo context of intact embryos. Recent efforts, using the intrinsic capacity of embryonic stem cells to self-assemble and generate embryo-like structures de novo, have opened new avenues for understanding the many ways by which an embryo can be built and the influence of extrinsic factors therein. Here, we discuss and compare divergent and conserved strategies leading to germ layer formation in embryos as compared to in vitro systems, their upstream molecular cascades and the role of extrinsic factors in this process. acknowledgement: We thank Nicoletta Petridou, Diana Pinheiro, Cornelia Schwayer and Stefania Tavano for feedback on the manuscript. Research in the Heisenberg lab is supported by an ERC Advanced Grant (MECSPEC 742573) to C.-P.H. A.S. is a recipient of a DOC Fellowship of the Austrian Academy of Science. article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Alexandra full_name: Schauer, Alexandra id: 30A536BA-F248-11E8-B48F-1D18A9856A87 last_name: Schauer orcid: 0000-0001-7659-9142 - first_name: Carl-Philipp J full_name: Heisenberg, Carl-Philipp J id: 39427864-F248-11E8-B48F-1D18A9856A87 last_name: Heisenberg orcid: 0000-0002-0912-4566 citation: ama: Schauer A, Heisenberg C-PJ. Reassembling gastrulation. Developmental Biology. 2021;474:71-81. doi:10.1016/j.ydbio.2020.12.014 apa: Schauer, A., & Heisenberg, C.-P. J. (2021). Reassembling gastrulation. Developmental Biology. Elsevier. https://doi.org/10.1016/j.ydbio.2020.12.014 chicago: Schauer, Alexandra, and Carl-Philipp J Heisenberg. “Reassembling Gastrulation.” Developmental Biology. Elsevier, 2021. https://doi.org/10.1016/j.ydbio.2020.12.014. ieee: A. Schauer and C.-P. J. Heisenberg, “Reassembling gastrulation,” Developmental Biology, vol. 474. Elsevier, pp. 71–81, 2021. ista: Schauer A, Heisenberg C-PJ. 2021. Reassembling gastrulation. Developmental Biology. 474, 71–81. mla: Schauer, Alexandra, and Carl-Philipp J. Heisenberg. “Reassembling Gastrulation.” Developmental Biology, vol. 474, Elsevier, 2021, pp. 71–81, doi:10.1016/j.ydbio.2020.12.014. short: A. Schauer, C.-P.J. Heisenberg, Developmental Biology 474 (2021) 71–81. date_created: 2020-12-22T09:53:34Z date_published: 2021-06-01T00:00:00Z date_updated: 2026-11-12T23:30:10Z day: '01' ddc: - '570' department: - _id: CaHe doi: 10.1016/j.ydbio.2020.12.014 ec_funded: 1 external_id: isi: - '000639461800008' pmid: - '33352181' file: - access_level: open_access checksum: fa2a5731fd16ab171b029f32f031c440 content_type: application/pdf creator: kschuh date_created: 2021-08-11T10:28:06Z date_updated: 2021-08-11T10:28:06Z file_id: '9880' file_name: 2021_DevBiology_Schauer.pdf file_size: 1440321 relation: main_file success: 1 file_date_updated: 2021-08-11T10:28:06Z fulldoi: https://doi.org/10.1016/j.ydbio.2020.12.014 has_accepted_license: '1' intvolume: ' 474' isi: 1 keyword: - Developmental Biology - Cell Biology - Molecular Biology language: - iso: eng license: https://creativecommons.org/licenses/by-nc-nd/4.0/ month: '06' oa: 1 oa_version: Published Version page: 71-81 pmid: 1 project: - _id: 260F1432-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '742573' name: Interaction and feedback between cell mechanics and fate specification in vertebrate gastrulation - _id: 26B1E39C-B435-11E9-9278-68D0E5697425 grant_number: '25239' name: 'Mesendoderm specification in zebrafish: The role of extraembryonic tissues' publication: Developmental Biology publication_identifier: issn: - 0012-1606 publication_status: published publisher: Elsevier quality_controlled: '1' related_material: record: - id: '12891' relation: dissertation_contains status: public scopus_import: '1' status: public title: Reassembling gastrulation tmp: image: /images/cc_by_nc_nd.png legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) short: CC BY-NC-ND (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 474 year: '2021' ... --- _id: '9438' abstract: - lang: eng text: Rigorous investigation of synaptic transmission requires analysis of unitary synaptic events by simultaneous recording from presynaptic terminals and postsynaptic target neurons. However, this has been achieved at only a limited number of model synapses, including the squid giant synapse and the mammalian calyx of Held. Cortical presynaptic terminals have been largely inaccessible to direct presynaptic recording, due to their small size. Here, we describe a protocol for improved subcellular patch-clamp recording in rat and mouse brain slices, with the synapse in a largely intact environment. Slice preparation takes ~2 h, recording ~3 h and post hoc morphological analysis 2 d. Single presynaptic hippocampal mossy fiber terminals are stimulated minimally invasively in the bouton-attached configuration, in which the cytoplasmic content remains unperturbed, or in the whole-bouton configuration, in which the cytoplasmic composition can be precisely controlled. Paired pre–postsynaptic recordings can be integrated with biocytin labeling and morphological analysis, allowing correlative investigation of synapse structure and function. Paired recordings can be obtained from mossy fiber terminals in slices from both rats and mice, implying applicability to genetically modified synapses. Paired recordings can also be performed together with axon tract stimulation or optogenetic activation, allowing comparison of unitary and compound synaptic events in the same target cell. Finally, paired recordings can be combined with spontaneous event analysis, permitting collection of miniature events generated at a single identified synapse. In conclusion, the subcellular patch-clamp techniques detailed here should facilitate analysis of biophysics, plasticity and circuit function of cortical synapses in the mammalian central nervous system. acknowledged_ssus: - _id: M-Shop acknowledgement: This project received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement no. 692692 to P.J.) and the Fond zur Förderung der Wissenschaftlichen Forschung (Z 312-B27, Wittgenstein award to P.J., V 739-B27 to C.B.M.). We are grateful to F. Marr and C. Altmutter for excellent technical assistance and cell reconstruction, E. Kralli-Beller for manuscript editing, and the Scientific Service Units of IST Austria, especially T. Asenov and Miba machine shop, for maximally efficient support. article_processing_charge: No article_type: original author: - first_name: David H full_name: Vandael, David H id: 3AE48E0A-F248-11E8-B48F-1D18A9856A87 last_name: Vandael orcid: 0000-0001-7577-1676 - first_name: Yuji full_name: Okamoto, Yuji id: 3337E116-F248-11E8-B48F-1D18A9856A87 last_name: Okamoto orcid: 0000-0003-0408-6094 - first_name: Carolina full_name: Borges Merjane, Carolina id: 4305C450-F248-11E8-B48F-1D18A9856A87 last_name: Borges Merjane orcid: 0000-0003-0005-401X - first_name: Victor M full_name: Vargas Barroso, Victor M id: 2F55A9DE-F248-11E8-B48F-1D18A9856A87 last_name: Vargas Barroso - first_name: Benjamin full_name: Suter, Benjamin id: 4952F31E-F248-11E8-B48F-1D18A9856A87 last_name: Suter orcid: 0000-0002-9885-6936 - first_name: Peter M full_name: Jonas, Peter M id: 353C1B58-F248-11E8-B48F-1D18A9856A87 last_name: Jonas orcid: 0000-0001-5001-4804 citation: ama: Vandael DH, Okamoto Y, Borges Merjane C, Vargas Barroso VM, Suter B, Jonas PM. Subcellular patch-clamp techniques for single-bouton stimulation and simultaneous pre- and postsynaptic recording at cortical synapses. Nature Protocols. 2021;16(6):2947–2967. doi:10.1038/s41596-021-00526-0 apa: Vandael, D. H., Okamoto, Y., Borges Merjane, C., Vargas Barroso, V. M., Suter, B., & Jonas, P. M. (2021). Subcellular patch-clamp techniques for single-bouton stimulation and simultaneous pre- and postsynaptic recording at cortical synapses. Nature Protocols. Springer Nature. https://doi.org/10.1038/s41596-021-00526-0 chicago: Vandael, David H, Yuji Okamoto, Carolina Borges Merjane, Victor M Vargas Barroso, Benjamin Suter, and Peter M Jonas. “Subcellular Patch-Clamp Techniques for Single-Bouton Stimulation and Simultaneous Pre- and Postsynaptic Recording at Cortical Synapses.” Nature Protocols. Springer Nature, 2021. https://doi.org/10.1038/s41596-021-00526-0. ieee: D. H. Vandael, Y. Okamoto, C. Borges Merjane, V. M. Vargas Barroso, B. Suter, and P. M. Jonas, “Subcellular patch-clamp techniques for single-bouton stimulation and simultaneous pre- and postsynaptic recording at cortical synapses,” Nature Protocols, vol. 16, no. 6. Springer Nature, pp. 2947–2967, 2021. ista: Vandael DH, Okamoto Y, Borges Merjane C, Vargas Barroso VM, Suter B, Jonas PM. 2021. Subcellular patch-clamp techniques for single-bouton stimulation and simultaneous pre- and postsynaptic recording at cortical synapses. Nature Protocols. 16(6), 2947–2967. mla: Vandael, David H., et al. “Subcellular Patch-Clamp Techniques for Single-Bouton Stimulation and Simultaneous Pre- and Postsynaptic Recording at Cortical Synapses.” Nature Protocols, vol. 16, no. 6, Springer Nature, 2021, pp. 2947–2967, doi:10.1038/s41596-021-00526-0. short: D.H. Vandael, Y. Okamoto, C. Borges Merjane, V.M. Vargas Barroso, B. Suter, P.M. Jonas, Nature Protocols 16 (2021) 2947–2967. corr_author: '1' date_created: 2021-05-30T22:01:24Z date_published: 2021-06-01T00:00:00Z date_updated: 2025-04-22T22:30:43Z day: '01' ddc: - '570' department: - _id: PeJo doi: 10.1038/s41596-021-00526-0 ec_funded: 1 external_id: isi: - '000650528700003' pmid: - '33990799' file: - access_level: open_access checksum: 7eb580abd8893cdb0b410cf41bc8c263 content_type: application/pdf creator: cziletti date_created: 2021-07-08T12:27:55Z date_updated: 2021-12-02T23:30:05Z embargo: 2021-12-01 file_id: '9639' file_name: VandaeletalAuthorVersion2021.pdf file_size: 38574802 relation: main_file file_date_updated: 2021-12-02T23:30:05Z fulldoi: https://doi.org/10.1038/s41596-021-00526-0 has_accepted_license: '1' intvolume: ' 16' isi: 1 issue: '6' language: - iso: eng month: '06' oa: 1 oa_version: Submitted Version page: 2947–2967 pmid: 1 project: - _id: 25B7EB9E-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '692692' name: Biophysics and circuit function of a giant cortical glutamatergic synapse - _id: 25C5A090-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: Z00312 name: Synaptic communication in neuronal microcircuits - _id: 2696E7FE-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: V00739 name: Structural plasticity at mossy fiber-CA3 synapses publication: Nature Protocols publication_identifier: eissn: - 1750-2799 issn: - 1754-2189 publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: Subcellular patch-clamp techniques for single-bouton stimulation and simultaneous pre- and postsynaptic recording at cortical synapses type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 16 year: '2021' ... --- OA_place: publisher OA_type: hybrid _id: '7883' abstract: - lang: eng text: All vertebrates have a spinal cord with dimensions and shape specific to their species. Yet how species‐specific organ size and shape are achieved is a fundamental unresolved question in biology. The formation and sculpting of organs begins during embryonic development. As it develops, the spinal cord extends in anterior–posterior direction in synchrony with the overall growth of the body. The dorsoventral (DV) and apicobasal lengths of the spinal cord neuroepithelium also change, while at the same time a characteristic pattern of neural progenitor subtypes along the DV axis is established and elaborated. At the basis of these changes in tissue size and shape are biophysical determinants, such as the change in cell number, cell size and shape, and anisotropic tissue growth. These processes are controlled by global tissue‐scale regulators, such as morphogen signaling gradients as well as mechanical forces. Current challenges in the field are to uncover how these tissue‐scale regulatory mechanisms are translated to the cellular and molecular level, and how regulation of distinct cellular processes gives rise to an overall defined size. Addressing these questions will help not only to achieve a better understanding of how size is controlled, but also of how tissue size is coordinated with the specification of pattern. acknowledgement: 'Austrian Academy of Sciences, Grant/Award Number: DOC fellowship for Katarzyna Kuzmicz-Kowalska; Austrian Science Fund, Grant/Award Number: F78 (Stem Cell Modulation); H2020 European Research Council, Grant/Award Number: 680037' article_number: e383 article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Katarzyna full_name: Kuzmicz-Kowalska, Katarzyna id: 4CED352A-F248-11E8-B48F-1D18A9856A87 last_name: Kuzmicz-Kowalska - first_name: Anna full_name: Kicheva, Anna id: 3959A2A0-F248-11E8-B48F-1D18A9856A87 last_name: Kicheva orcid: 0000-0003-4509-4998 citation: ama: 'Kuzmicz-Kowalska K, Kicheva A. Regulation of size and scale in vertebrate spinal cord development. Wiley Interdisciplinary Reviews: Developmental Biology. 2021. doi:10.1002/wdev.383' apa: 'Kuzmicz-Kowalska, K., & Kicheva, A. (2021). Regulation of size and scale in vertebrate spinal cord development. Wiley Interdisciplinary Reviews: Developmental Biology. Wiley. https://doi.org/10.1002/wdev.383' chicago: 'Kuzmicz-Kowalska, Katarzyna, and Anna Kicheva. “Regulation of Size and Scale in Vertebrate Spinal Cord Development.” Wiley Interdisciplinary Reviews: Developmental Biology. Wiley, 2021. https://doi.org/10.1002/wdev.383.' ieee: 'K. Kuzmicz-Kowalska and A. Kicheva, “Regulation of size and scale in vertebrate spinal cord development,” Wiley Interdisciplinary Reviews: Developmental Biology. Wiley, 2021.' ista: 'Kuzmicz-Kowalska K, Kicheva A. 2021. Regulation of size and scale in vertebrate spinal cord development. Wiley Interdisciplinary Reviews: Developmental Biology., e383.' mla: 'Kuzmicz-Kowalska, Katarzyna, and Anna Kicheva. “Regulation of Size and Scale in Vertebrate Spinal Cord Development.” Wiley Interdisciplinary Reviews: Developmental Biology, e383, Wiley, 2021, doi:10.1002/wdev.383.' short: 'K. Kuzmicz-Kowalska, A. Kicheva, Wiley Interdisciplinary Reviews: Developmental Biology (2021).' corr_author: '1' date_created: 2020-05-24T22:01:00Z date_published: 2021-04-15T00:00:00Z date_updated: 2026-11-12T23:30:17Z day: '15' ddc: - '570' department: - _id: AnKi doi: 10.1002/wdev.383 ec_funded: 1 external_id: isi: - '000531419400001' pmid: - '32391980' file: - access_level: open_access checksum: f0a7745d48afa09ea7025e876a0145a8 content_type: application/pdf creator: dernst date_created: 2020-11-24T13:11:39Z date_updated: 2020-11-24T13:11:39Z file_id: '8800' file_name: 2020_WIREs_DevBio_KuzmiczKowalska.pdf file_size: 2527276 relation: main_file success: 1 file_date_updated: 2020-11-24T13:11:39Z fulldoi: https://doi.org/10.1002/wdev.383 has_accepted_license: '1' isi: 1 language: - iso: eng month: '04' oa: 1 oa_version: Published Version pmid: 1 project: - _id: B6FC0238-B512-11E9-945C-1524E6697425 call_identifier: H2020 grant_number: '680037' name: Coordination of Patterning And Growth In the Spinal Cord - _id: 267AF0E4-B435-11E9-9278-68D0E5697425 name: The role of morphogens in the regulation of neural tube growth - _id: 059DF620-7A3F-11EA-A408-12923DDC885E grant_number: F7802 name: Stem Cell Modulation in Neural Development and Regeneration/ P02-Morphogen control of growth and pattern in the spinal cord publication: 'Wiley Interdisciplinary Reviews: Developmental Biology' publication_identifier: eissn: - 1759-7692 issn: - 1759-7684 publication_status: published publisher: Wiley quality_controlled: '1' related_material: record: - id: '14323' relation: dissertation_contains status: public scopus_import: '1' status: public title: Regulation of size and scale in vertebrate spinal cord development tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2021' ... --- _id: '9349' abstract: - lang: eng text: 'The way in which interactions between mechanics and biochemistry lead to the emergence of complex cell and tissue organization is an old question that has recently attracted renewed interest from biologists, physicists, mathematicians and computer scientists. Rapid advances in optical physics, microscopy and computational image analysis have greatly enhanced our ability to observe and quantify spatiotemporal patterns of signalling, force generation, deformation, and flow in living cells and tissues. Powerful new tools for genetic, biophysical and optogenetic manipulation are allowing us to perturb the underlying machinery that generates these patterns in increasingly sophisticated ways. Rapid advances in theory and computing have made it possible to construct predictive models that describe how cell and tissue organization and dynamics emerge from the local coupling of biochemistry and mechanics. Together, these advances have opened up a wealth of new opportunities to explore how mechanochemical patterning shapes organismal development. In this roadmap, we present a series of forward-looking case studies on mechanochemical patterning in development, written by scientists working at the interface between the physical and biological sciences, and covering a wide range of spatial and temporal scales, organisms, and modes of development. Together, these contributions highlight the many ways in which the dynamic coupling of mechanics and biochemistry shapes biological dynamics: from mechanoenzymes that sense force to tune their activity and motor output, to collectives of cells in tissues that flow and redistribute biochemical signals during development.' acknowledgement: The AK group is supported by IST Austria and by the ERC under European Union Horizon 2020 research and innovation programme Grant 680037. Apologies to those whose work could not be mentioned due to limited space. We thank all my lab members, both past and present, for stimulating discussion. This work was funded by a Singapore Ministry of Education Tier 3 Grant, MOE2016-T3-1-005. We thank Francis Corson for continuous discussion and collaboration contributing to these views and for figure 4(A). PC is sponsored by the Institut Pasteur and the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie Grant Agreement No. 665807. Research in JG's laboratory is funded by the European Research Council under the European Union's Seventh Framework Programme (FP7/2007-2013)/ERC Grant Agreement No. 337635, Institut Pasteur, CNRS, Cercle FSER, Fondation pour la Recherche Medicale, the Vallee Foundation and the ANR-19-CE-13-0024 Grant. We thank Erez Braun and Alex Mogilner for comments on the manuscript and Niv Ierushalmi for help with figure 5. This project has received funding from the European Union's Horizon 2020 research and innovation programme under Grant Agreement No. ERC-2018-COG Grant 819174-HydraMechanics awarded to KK. EH thanks all lab members, as well as Pierre Recho, Tsuyoshi Hirashima, Diana Pinheiro and Carl-Philip Heisenberg, for fruitful discussions on these topics—and apologize for not being able to cite many very relevant publications due to the strict 10-reference limit. EH acknowledges the support of Austrian Science Fund (FWF) (P 31639) and the European Research Council under the European Union's Horizon 2020 Research and Innovation Programme Grant Agreements (851288). The authors acknowledge the inspiring scientists whose work could not be cited in this perspective due to space constraints; the members of the Gartner Lab for helpful discussions; the Barbara and Gerson Bakar Foundation, the Chan Zuckerberg Biohub Investigators Programme, the National Institute of Health, and the Centre for Cellular Construction, an NSF Science and Technology Centre. The Minc laboratory is currently funded by the CNRS and the European Research Council (CoG Forcaster No. 647073). Research in the lab of J-LM is supported by the Institut Curie, the Centre National de la Recherche Scientifique (CNRS), the Institut National de la Santé Et de la Recherche Médicale (INSERM), and is funded by grants from the ATIP-Avenir programme, the Fondation Schlumberger pour l'Éducation et la Recherche via the Fondation pour la Recherche Médicale, the European Research Council Starting Grant ERC-2017-StG 757557, the European Molecular Biology Organization Young Investigator programme (EMBO YIP), the INSERM transversal programme Human Development Cell Atlas (HuDeCA), Paris Sciences Lettres (PSL) 'nouvelle équipe' and QLife (17-CONV-0005) grants and Labex DEEP (ANR-11-LABX-0044) which are part of the IDEX PSL (ANR-10-IDEX-0001-02). We acknowledge useful discussions with Massimo Vergassola, Sebastian Streichan and my lab members. Work in my laboratory on Drosophila embryogenesis is partly supported by NIH-R01GM122936. The authors acknowledge the support by a grant from the European Research Council (Grant No. 682161). Lenne group is funded by a grant from the 'Investissements d'Avenir' French Government programme managed by the French National Research Agency (ANR-16-CONV-0001) and by the Excellence Initiative of Aix-Marseille University—A*MIDEX, and ANR projects MechaResp (ANR-17-CE13-0032) and AdGastrulo (ANR-19-CE13-0022). article_number: '041501' article_processing_charge: No article_type: original author: - first_name: Pierre François full_name: Lenne, Pierre François last_name: Lenne - first_name: Edwin full_name: Munro, Edwin last_name: Munro - first_name: Idse full_name: Heemskerk, Idse last_name: Heemskerk - first_name: Aryeh full_name: Warmflash, Aryeh last_name: Warmflash - first_name: Laura full_name: Bocanegra, Laura id: 4896F754-F248-11E8-B48F-1D18A9856A87 last_name: Bocanegra - first_name: Kasumi full_name: Kishi, Kasumi id: 3065DFC4-F248-11E8-B48F-1D18A9856A87 last_name: Kishi orcid: 0000-0001-6060-4795 - first_name: Anna full_name: Kicheva, Anna id: 3959A2A0-F248-11E8-B48F-1D18A9856A87 last_name: Kicheva orcid: 0000-0003-4509-4998 - first_name: Yuchen full_name: Long, Yuchen last_name: Long - first_name: Antoine full_name: Fruleux, Antoine last_name: Fruleux - first_name: Arezki full_name: Boudaoud, Arezki last_name: Boudaoud - first_name: Timothy E. full_name: Saunders, Timothy E. last_name: Saunders - first_name: Paolo full_name: Caldarelli, Paolo last_name: Caldarelli - first_name: Arthur full_name: Michaut, Arthur last_name: Michaut - first_name: Jerome full_name: Gros, Jerome last_name: Gros - first_name: Yonit full_name: Maroudas-Sacks, Yonit last_name: Maroudas-Sacks - first_name: Kinneret full_name: Keren, Kinneret last_name: Keren - first_name: Edouard B full_name: Hannezo, Edouard B id: 3A9DB764-F248-11E8-B48F-1D18A9856A87 last_name: Hannezo orcid: 0000-0001-6005-1561 - first_name: Zev J. full_name: Gartner, Zev J. last_name: Gartner - first_name: Benjamin full_name: Stormo, Benjamin last_name: Stormo - first_name: Amy full_name: Gladfelter, Amy last_name: Gladfelter - first_name: Alan full_name: Rodrigues, Alan last_name: Rodrigues - first_name: Amy full_name: Shyer, Amy last_name: Shyer - first_name: Nicolas full_name: Minc, Nicolas last_name: Minc - first_name: Jean Léon full_name: Maître, Jean Léon last_name: Maître - first_name: Stefano full_name: Di Talia, Stefano last_name: Di Talia - first_name: Bassma full_name: Khamaisi, Bassma last_name: Khamaisi - first_name: David full_name: Sprinzak, David last_name: Sprinzak - first_name: Sham full_name: Tlili, Sham last_name: Tlili citation: ama: Lenne PF, Munro E, Heemskerk I, et al. Roadmap for the multiscale coupling of biochemical and mechanical signals during development. Physical biology. 2021;18(4). doi:10.1088/1478-3975/abd0db apa: Lenne, P. F., Munro, E., Heemskerk, I., Warmflash, A., Bocanegra, L., Kishi, K., … Tlili, S. (2021). Roadmap for the multiscale coupling of biochemical and mechanical signals during development. Physical Biology. IOP Publishing. https://doi.org/10.1088/1478-3975/abd0db chicago: Lenne, Pierre François, Edwin Munro, Idse Heemskerk, Aryeh Warmflash, Laura Bocanegra, Kasumi Kishi, Anna Kicheva, et al. “Roadmap for the Multiscale Coupling of Biochemical and Mechanical Signals during Development.” Physical Biology. IOP Publishing, 2021. https://doi.org/10.1088/1478-3975/abd0db. ieee: P. F. Lenne et al., “Roadmap for the multiscale coupling of biochemical and mechanical signals during development,” Physical biology, vol. 18, no. 4. IOP Publishing, 2021. ista: Lenne PF, Munro E, Heemskerk I, Warmflash A, Bocanegra L, Kishi K, Kicheva A, Long Y, Fruleux A, Boudaoud A, Saunders TE, Caldarelli P, Michaut A, Gros J, Maroudas-Sacks Y, Keren K, Hannezo EB, Gartner ZJ, Stormo B, Gladfelter A, Rodrigues A, Shyer A, Minc N, Maître JL, Di Talia S, Khamaisi B, Sprinzak D, Tlili S. 2021. Roadmap for the multiscale coupling of biochemical and mechanical signals during development. Physical biology. 18(4), 041501. mla: Lenne, Pierre François, et al. “Roadmap for the Multiscale Coupling of Biochemical and Mechanical Signals during Development.” Physical Biology, vol. 18, no. 4, 041501, IOP Publishing, 2021, doi:10.1088/1478-3975/abd0db. short: P.F. Lenne, E. Munro, I. Heemskerk, A. Warmflash, L. Bocanegra, K. Kishi, A. Kicheva, Y. Long, A. Fruleux, A. Boudaoud, T.E. Saunders, P. Caldarelli, A. Michaut, J. Gros, Y. Maroudas-Sacks, K. Keren, E.B. Hannezo, Z.J. Gartner, B. Stormo, A. Gladfelter, A. Rodrigues, A. Shyer, N. Minc, J.L. Maître, S. Di Talia, B. Khamaisi, D. Sprinzak, S. Tlili, Physical Biology 18 (2021). date_created: 2021-04-25T22:01:29Z date_published: 2021-04-14T00:00:00Z date_updated: 2026-11-12T23:30:19Z day: '14' ddc: - '570' department: - _id: AnKi - _id: EdHa doi: 10.1088/1478-3975/abd0db ec_funded: 1 external_id: isi: - '000640396400001' pmid: - '33276350' file: - access_level: open_access checksum: 4f52082549d3561c4c15d4d8d84ca5d8 content_type: application/pdf creator: cziletti date_created: 2021-04-27T08:38:35Z date_updated: 2021-04-27T08:38:35Z file_id: '9355' file_name: 2021_PhysBio_Lenne.pdf file_size: 6296324 relation: main_file success: 1 file_date_updated: 2021-04-27T08:38:35Z fulldoi: https://doi.org/10.1088/1478-3975/abd0db has_accepted_license: '1' intvolume: ' 18' isi: 1 issue: '4' language: - iso: eng month: '04' oa: 1 oa_version: Published Version pmid: 1 project: - _id: B6FC0238-B512-11E9-945C-1524E6697425 call_identifier: H2020 grant_number: '680037' name: Coordination of Patterning And Growth In the Spinal Cord - _id: 268294B6-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: P31639 name: Active mechano-chemical description of the cell cytoskeleton - _id: 05943252-7A3F-11EA-A408-12923DDC885E call_identifier: H2020 grant_number: '851288' name: Design Principles of Branching Morphogenesis publication: Physical biology publication_identifier: eissn: - 1478-3975 publication_status: published publisher: IOP Publishing quality_controlled: '1' related_material: record: - id: '13081' relation: dissertation_contains status: public scopus_import: '1' status: public title: Roadmap for the multiscale coupling of biochemical and mechanical signals during development tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8 volume: 18 year: '2021' ... --- _id: '9250' abstract: - lang: eng text: Aprotic alkali metal–O2 batteries face two major obstacles to their chemistry occurring efficiently, the insulating nature of the formed alkali superoxides/peroxides and parasitic reactions that are caused by the highly reactive singlet oxygen (1O2). Redox mediators are recognized to be key for improving rechargeability. However, it is unclear how they affect 1O2 formation, which hinders strategies for their improvement. Here we clarify the mechanism of mediated peroxide and superoxide oxidation and thus explain how redox mediators either enhance or suppress 1O2 formation. We show that charging commences with peroxide oxidation to a superoxide intermediate and that redox potentials above ~3.5 V versus Li/Li+ drive 1O2 evolution from superoxide oxidation, while disproportionation always generates some 1O2. We find that 1O2 suppression requires oxidation to be faster than the generation of 1O2 from disproportionation. Oxidation rates decrease with growing driving force following Marcus inverted-region behaviour, establishing a region of maximum rate. acknowledged_ssus: - _id: M-Shop acknowledgement: S.A.F. is indebted to the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No. 636069) as well as IST Austria. O.F thanks the French National Research Agency (STORE-EX Labex Project ANR-10-LABX-76-01). We thank EL-Cell GmbH (Hamburg, Germany) for the pressure test cell. We thank R. Saf for help with the mass spectrometry, J. Schlegl for manufacturing instrumentation, M. Winkler of Acib GmbH, G. Strohmeier and R. Fürst for HPLC measurements and S. Mondal and S. Stadlbauer for kinetic measurements. article_processing_charge: No article_type: original author: - first_name: Yann K. full_name: Petit, Yann K. last_name: Petit - first_name: Eléonore full_name: Mourad, Eléonore last_name: Mourad - first_name: Christian full_name: Prehal, Christian last_name: Prehal - first_name: Christian full_name: Leypold, Christian last_name: Leypold - first_name: Andreas full_name: Windischbacher, Andreas last_name: Windischbacher - first_name: Daniel full_name: Mijailovic, Daniel last_name: Mijailovic - first_name: Christian full_name: Slugovc, Christian last_name: Slugovc - first_name: Sergey M. full_name: Borisov, Sergey M. last_name: Borisov - first_name: Egbert full_name: Zojer, Egbert last_name: Zojer - first_name: Sergio full_name: Brutti, Sergio last_name: Brutti - first_name: Olivier full_name: Fontaine, Olivier last_name: Fontaine - first_name: Stefan Alexander full_name: Freunberger, Stefan Alexander id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425 last_name: Freunberger orcid: 0000-0003-2902-5319 citation: ama: Petit YK, Mourad E, Prehal C, et al. Mechanism of mediated alkali peroxide oxidation and triplet versus singlet oxygen formation. Nature Chemistry. 2021;13(5):465-471. doi:10.1038/s41557-021-00643-z apa: Petit, Y. K., Mourad, E., Prehal, C., Leypold, C., Windischbacher, A., Mijailovic, D., … Freunberger, S. A. (2021). Mechanism of mediated alkali peroxide oxidation and triplet versus singlet oxygen formation. Nature Chemistry. Springer Nature. https://doi.org/10.1038/s41557-021-00643-z chicago: Petit, Yann K., Eléonore Mourad, Christian Prehal, Christian Leypold, Andreas Windischbacher, Daniel Mijailovic, Christian Slugovc, et al. “Mechanism of Mediated Alkali Peroxide Oxidation and Triplet versus Singlet Oxygen Formation.” Nature Chemistry. Springer Nature, 2021. https://doi.org/10.1038/s41557-021-00643-z. ieee: Y. K. Petit et al., “Mechanism of mediated alkali peroxide oxidation and triplet versus singlet oxygen formation,” Nature Chemistry, vol. 13, no. 5. Springer Nature, pp. 465–471, 2021. ista: Petit YK, Mourad E, Prehal C, Leypold C, Windischbacher A, Mijailovic D, Slugovc C, Borisov SM, Zojer E, Brutti S, Fontaine O, Freunberger SA. 2021. Mechanism of mediated alkali peroxide oxidation and triplet versus singlet oxygen formation. Nature Chemistry. 13(5), 465–471. mla: Petit, Yann K., et al. “Mechanism of Mediated Alkali Peroxide Oxidation and Triplet versus Singlet Oxygen Formation.” Nature Chemistry, vol. 13, no. 5, Springer Nature, 2021, pp. 465–71, doi:10.1038/s41557-021-00643-z. short: Y.K. Petit, E. Mourad, C. Prehal, C. Leypold, A. Windischbacher, D. Mijailovic, C. Slugovc, S.M. Borisov, E. Zojer, S. Brutti, O. Fontaine, S.A. Freunberger, Nature Chemistry 13 (2021) 465–471. corr_author: '1' date_created: 2021-03-16T11:12:20Z date_published: 2021-03-15T00:00:00Z date_updated: 2024-10-09T21:00:28Z day: '15' ddc: - '540' department: - _id: StFr doi: 10.1038/s41557-021-00643-z external_id: isi: - '000629296400001' pmid: - '33723377' file: - access_level: open_access checksum: 3ee3f8dd79ed1b7bb0929fce184c8012 content_type: application/pdf creator: dernst date_created: 2021-03-22T11:46:00Z date_updated: 2021-09-16T22:30:03Z embargo: 2021-09-15 file_id: '9276' file_name: 2021_NatureChem_Petit_acceptedVersion.pdf file_size: 1811448 relation: main_file file_date_updated: 2021-09-16T22:30:03Z fulldoi: https://doi.org/10.1038/s41557-021-00643-z has_accepted_license: '1' intvolume: ' 13' isi: 1 issue: '5' keyword: - General Chemistry - General Chemical Engineering language: - iso: eng month: '03' oa: 1 oa_version: Submitted Version page: 465-471 pmid: 1 publication: Nature Chemistry publication_identifier: eissn: - 1755-4349 issn: - 1755-4330 publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: Mechanism of mediated alkali peroxide oxidation and triplet versus singlet oxygen formation type: journal_article user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1 volume: 13 year: '2021' ... --- _id: '9428' abstract: - lang: eng text: Thermalization is the inevitable fate of many complex quantum systems, whose dynamics allow them to fully explore the vast configuration space regardless of the initial state---the behaviour known as quantum ergodicity. In a quest for experimental realizations of coherent long-time dynamics, efforts have focused on ergodicity-breaking mechanisms, such as integrability and localization. The recent discovery of persistent revivals in quantum simulators based on Rydberg atoms have pointed to the existence of a new type of behaviour where the system rapidly relaxes for most initial conditions, while certain initial states give rise to non-ergodic dynamics. This collective effect has been named ”quantum many-body scarring’by analogy with a related form of weak ergodicity breaking that occurs for a single particle inside a stadium billiard potential. In this Review, we provide a pedagogical introduction to quantum many-body scars and highlight the emerging connections with the semiclassical quantization of many-body systems. We discuss the relation between scars and more general routes towards weak violations of ergodicity due to embedded algebras and non-thermal eigenstates, and highlight possible applications of scars in quantum technology. acknowledgement: We thank our collaborators K. Bull, S. Choi, J.-Y. Desaules, W. W. Ho, A. Hudomal, M. Lukin, I. Martin, H. Pichler, N. Regnault, I. Vasić and in particular A. Michailidis and C. Turner, without whom this work would not have been possible. We also benefited from discussions with E. Altman, B. A. Bernevig, A. Chandran, P. Fendley, V. Khemani and L. Motrunich. M.S. was supported by the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement no. 850899). D.A.A. was supported by the Swiss National Science Foundation and by the ERC under the European Union’s Horizon 2020 research and innovation programme (grant agreement no. 864597). Z.P. acknowledges support by the Leverhulme Trust Research Leadership Award RL-2019-015. article_processing_charge: No article_type: review arxiv: 1 author: - first_name: Maksym full_name: Serbyn, Maksym id: 47809E7E-F248-11E8-B48F-1D18A9856A87 last_name: Serbyn orcid: 0000-0002-2399-5827 - first_name: Dmitry A. full_name: Abanin, Dmitry A. last_name: Abanin - first_name: Zlatko full_name: Papić, Zlatko last_name: Papić citation: ama: Serbyn M, Abanin DA, Papić Z. Quantum many-body scars and weak breaking of ergodicity. Nature Physics. 2021;17(6):675–685. doi:10.1038/s41567-021-01230-2 apa: Serbyn, M., Abanin, D. A., & Papić, Z. (2021). Quantum many-body scars and weak breaking of ergodicity. Nature Physics. Nature Research. https://doi.org/10.1038/s41567-021-01230-2 chicago: Serbyn, Maksym, Dmitry A. Abanin, and Zlatko Papić. “Quantum Many-Body Scars and Weak Breaking of Ergodicity.” Nature Physics. Nature Research, 2021. https://doi.org/10.1038/s41567-021-01230-2. ieee: M. Serbyn, D. A. Abanin, and Z. Papić, “Quantum many-body scars and weak breaking of ergodicity,” Nature Physics, vol. 17, no. 6. Nature Research, pp. 675–685, 2021. ista: Serbyn M, Abanin DA, Papić Z. 2021. Quantum many-body scars and weak breaking of ergodicity. Nature Physics. 17(6), 675–685. mla: Serbyn, Maksym, et al. “Quantum Many-Body Scars and Weak Breaking of Ergodicity.” Nature Physics, vol. 17, no. 6, Nature Research, 2021, pp. 675–685, doi:10.1038/s41567-021-01230-2. short: M. Serbyn, D.A. Abanin, Z. Papić, Nature Physics 17 (2021) 675–685. date_created: 2021-05-28T09:03:50Z date_published: 2021-06-01T00:00:00Z date_updated: 2025-04-14T07:52:09Z day: '01' ddc: - '539' department: - _id: MaSe doi: 10.1038/s41567-021-01230-2 ec_funded: 1 external_id: arxiv: - '2011.09486' isi: - '000655563800002' file: - access_level: open_access checksum: 316ed42ea1b42b0f1a3025bb476266fc content_type: application/pdf creator: patrickd date_created: 2021-09-20T09:27:43Z date_updated: 2021-12-02T23:30:03Z embargo: 2021-12-01 file_id: '10026' file_name: RevisedQMBSreview.pdf file_size: 10028836 relation: main_file file_date_updated: 2021-12-02T23:30:03Z fulldoi: https://doi.org/10.1038/s41567-021-01230-2 has_accepted_license: '1' intvolume: ' 17' isi: 1 issue: '6' language: - iso: eng month: '06' oa: 1 oa_version: Preprint page: 675–685 project: - _id: 23841C26-32DE-11EA-91FC-C7463DDC885E call_identifier: H2020 grant_number: '850899' name: 'Non-Ergodic Quantum Matter: Universality, Dynamics and Control' publication: Nature Physics publication_identifier: eissn: - 1745-2481 publication_status: published publisher: Nature Research quality_controlled: '1' scopus_import: '1' status: public title: Quantum many-body scars and weak breaking of ergodicity type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 17 year: '2021' ... --- OA_place: publisher _id: '9397' abstract: - lang: eng text: Accumulation of interstitial fluid (IF) between embryonic cells is a common phenomenon in vertebrate embryogenesis. Unlike other model systems, where these accumulations coalesce into a large central cavity – the blastocoel, in zebrafish, IF is more uniformly distributed between the deep cells (DC) before the onset of gastrulation. This is likely due to the presence of a large extraembryonic structure – the yolk cell (YC) at the position where the blastocoel typically forms in other model organisms. IF has long been speculated to play a role in tissue morphogenesis during embryogenesis, but direct evidence supporting such function is still sparse. Here we show that the relocalization of IF to the interface between the YC and DC/epiblast is critical for axial mesendoderm (ME) cell protrusion formation and migration along this interface, a key process in embryonic axis formation. We further demonstrate that axial ME cell migration and IF relocalization engage in a positive feedback loop, where axial ME migration triggers IF accumulation ahead of the advancing axial ME tissue by mechanically compressing the overlying epiblast cell layer. Upon compression, locally induced flow relocalizes the IF through the porous epiblast tissue resulting in an IF accumulation ahead of the leading axial ME. This IF accumulation, in turn, promotes cell protrusion formation and migration of the leading axial ME cells, thereby facilitating axial ME extension. Our findings reveal a central role of dynamic IF relocalization in orchestrating germ layer morphogenesis during gastrulation. alternative_title: - ISTA Thesis article_processing_charge: No author: - first_name: Karla full_name: Huljev, Karla id: 44C6F6A6-F248-11E8-B48F-1D18A9856A87 last_name: Huljev citation: ama: Huljev K. Coordinated spatiotemporal reorganization of interstitial fluid is required for axial mesendoderm migration in zebrafish gastrulation. 2021. doi:10.15479/at:ista:9397 apa: Huljev, K. (2021). Coordinated spatiotemporal reorganization of interstitial fluid is required for axial mesendoderm migration in zebrafish gastrulation. Institute of Science and Technology Austria. https://doi.org/10.15479/at:ista:9397 chicago: Huljev, Karla. “Coordinated Spatiotemporal Reorganization of Interstitial Fluid Is Required for Axial Mesendoderm Migration in Zebrafish Gastrulation.” Institute of Science and Technology Austria, 2021. https://doi.org/10.15479/at:ista:9397. ieee: K. Huljev, “Coordinated spatiotemporal reorganization of interstitial fluid is required for axial mesendoderm migration in zebrafish gastrulation,” Institute of Science and Technology Austria, 2021. ista: Huljev K. 2021. Coordinated spatiotemporal reorganization of interstitial fluid is required for axial mesendoderm migration in zebrafish gastrulation. Institute of Science and Technology Austria. mla: Huljev, Karla. Coordinated Spatiotemporal Reorganization of Interstitial Fluid Is Required for Axial Mesendoderm Migration in Zebrafish Gastrulation. Institute of Science and Technology Austria, 2021, doi:10.15479/at:ista:9397. short: K. Huljev, Coordinated Spatiotemporal Reorganization of Interstitial Fluid Is Required for Axial Mesendoderm Migration in Zebrafish Gastrulation, Institute of Science and Technology Austria, 2021. corr_author: '1' date_created: 2021-05-17T12:31:30Z date_published: 2021-05-18T00:00:00Z date_updated: 2026-04-08T07:12:51Z day: '18' ddc: - '571' degree_awarded: PhD department: - _id: CaHe - _id: GradSch doi: 10.15479/at:ista:9397 file: - access_level: closed checksum: 7f98532f5324a0b2f3fa8de2967baa19 content_type: application/vnd.openxmlformats-officedocument.wordprocessingml.document creator: khuljev date_created: 2021-05-17T12:29:12Z date_updated: 2022-05-21T22:30:04Z embargo_to: open_access file_id: '9398' file_name: KHuljev_Thesis_corrections.docx file_size: 47799741 relation: source_file - access_level: open_access checksum: bf512f8a1e572a543778fc4b227c01ba content_type: application/pdf creator: khuljev date_created: 2021-05-18T14:50:28Z date_updated: 2022-05-21T22:30:04Z embargo: 2022-05-20 file_id: '9401' file_name: new_KHuljev_Thesis_corrections.pdf file_size: 16542131 relation: main_file file_date_updated: 2022-05-21T22:30:04Z fulldoi: https://doi.org/10.15479/at:ista:9397 has_accepted_license: '1' language: - iso: eng month: '05' oa: 1 oa_version: Published Version page: '101' publication_identifier: issn: - 2663-337X publication_status: published publisher: Institute of Science and Technology Austria status: public supervisor: - first_name: Carl-Philipp J full_name: Heisenberg, Carl-Philipp J id: 39427864-F248-11E8-B48F-1D18A9856A87 last_name: Heisenberg orcid: 0000-0002-0912-4566 title: Coordinated spatiotemporal reorganization of interstitial fluid is required for axial mesendoderm migration in zebrafish gastrulation type: dissertation user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd year: '2021' ... --- OA_place: publisher _id: '9992' abstract: - lang: eng text: "Blood – this is what animals use to heal wounds fast and efficient. Plants do not have blood circulation and their cells cannot move. However, plants have evolved remarkable capacities to regenerate tissues and organs preventing further damage. In my PhD research, I studied the wound healing in the Arabidopsis root. I used a UV laser to ablate single cells in the root tip and observed the consequent wound healing. Interestingly, the inner adjacent cells induced a\r\ndivision plane switch and subsequently adopted the cell type of the killed cell to replace it. We termed this form of wound healing “restorative divisions”. This initial observation triggered the questions of my PhD studies: How and why do cells orient their division planes, how do they feel the wound and why does this happen only in inner adjacent cells.\r\nFor answering these questions, I used a quite simple experimental setup: 5 day - old seedlings were stained with propidium iodide to visualize cell walls and dead cells; ablation was carried out using a special laser cutter and a confocal microscope. Adaptation of the novel vertical microscope system made it possible to observe wounds in real time. This revealed that restorative divisions occur at increased frequency compared to normal divisions. Additionally,\r\nthe major plant hormone auxin accumulates in wound adjacent cells and drives the expression of the wound-stress responsive transcription factor ERF115. Using this as a marker gene for wound responses, we found that an important part of wound signalling is the sensing of the collapse of the ablated cell. The collapse causes a radical pressure drop, which results in strong tissue deformations. These deformations manifest in an invasion of the now free spot specifically by the inner adjacent cells within seconds, probably because of higher pressure of the inner tissues. Long-term imaging revealed that those deformed cells continuously expand towards the wound hole and that this is crucial for the restorative division. These wound-expanding cells exhibit an abnormal, biphasic polarity of microtubule arrays\r\nbefore the division. Experiments inhibiting cell expansion suggest that it is the biphasic stretching that induces those MT arrays. Adapting the micromanipulator aspiration system from animal scientists at our institute confirmed the hypothesis that stretching influences microtubule stability. In conclusion, this shows that microtubules react to tissue deformation\r\nand this facilitates the observed division plane switch. This puts mechanical cues and tensions at the most prominent position for explaining the growth and wound healing properties of plants. Hence, it shines light onto the importance of understanding mechanical signal transduction. " acknowledged_ssus: - _id: Bio - _id: LifeSc alternative_title: - ISTA Thesis article_processing_charge: No author: - first_name: Lukas full_name: Hörmayer, Lukas id: 2EEE7A2A-F248-11E8-B48F-1D18A9856A87 last_name: Hörmayer orcid: 0000-0001-8295-2926 citation: ama: Hörmayer L. Wound healing in the Arabidopsis root meristem. 2021. doi:10.15479/at:ista:9992 apa: Hörmayer, L. (2021). Wound healing in the Arabidopsis root meristem. Institute of Science and Technology Austria. https://doi.org/10.15479/at:ista:9992 chicago: Hörmayer, Lukas. “Wound Healing in the Arabidopsis Root Meristem.” Institute of Science and Technology Austria, 2021. https://doi.org/10.15479/at:ista:9992. ieee: L. Hörmayer, “Wound healing in the Arabidopsis root meristem,” Institute of Science and Technology Austria, 2021. ista: Hörmayer L. 2021. Wound healing in the Arabidopsis root meristem. Institute of Science and Technology Austria. mla: Hörmayer, Lukas. Wound Healing in the Arabidopsis Root Meristem. Institute of Science and Technology Austria, 2021, doi:10.15479/at:ista:9992. short: L. Hörmayer, Wound Healing in the Arabidopsis Root Meristem, Institute of Science and Technology Austria, 2021. corr_author: '1' date_created: 2021-09-09T07:37:20Z date_published: 2021-09-13T00:00:00Z date_updated: 2026-04-08T07:11:47Z day: '13' ddc: - '575' degree_awarded: PhD department: - _id: GradSch - _id: JiFr doi: 10.15479/at:ista:9992 ec_funded: 1 file: - access_level: closed checksum: c763064adaa720e16066c1a4f9682bbb content_type: application/vnd.openxmlformats-officedocument.wordprocessingml.document creator: lhoermaye date_created: 2021-09-09T07:29:48Z date_updated: 2021-09-15T22:30:26Z embargo_to: open_access file_id: '9993' file_name: Thesis_vupload.docx file_size: 25179004 relation: source_file - access_level: open_access checksum: 53911b06e93d7cdbbf4c7f4c162fa70f content_type: application/pdf creator: lhoermaye date_created: 2021-09-09T14:25:08Z date_updated: 2021-09-15T22:30:26Z embargo: 2021-09-09 file_id: '9996' file_name: Thesis_vfinal_pdfa.pdf file_size: 6246900 relation: main_file file_date_updated: 2021-09-15T22:30:26Z fulldoi: https://doi.org/10.15479/at:ista:9992 has_accepted_license: '1' language: - iso: eng month: '09' oa: 1 oa_version: Published Version page: '168' project: - _id: 262EF96E-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: P29988 name: RNA-directed DNA methylation in plant development - _id: 261099A6-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '742985' name: Tracing Evolution of Auxin Transport and Polarity in Plants publication_identifier: issn: - 2663-337X publication_status: published publisher: Institute of Science and Technology Austria related_material: record: - id: '6943' relation: part_of_dissertation status: public - id: '8002' relation: part_of_dissertation status: public - id: '6351' relation: part_of_dissertation status: public status: public supervisor: - first_name: Jiří full_name: Friml, Jiří id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 title: Wound healing in the Arabidopsis root meristem tmp: image: /images/cc_by_nc_nd.png legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) short: CC BY-NC-ND (4.0) type: dissertation user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd year: '2021' ... --- OA_place: publisher _id: '9728' abstract: - lang: eng text: "Most real-world flows are multiphase, yet we know little about them compared to their single-phase counterparts. Multiphase flows are more difficult to investigate as their dynamics occur in large parameter space and involve complex phenomena such as preferential concentration, turbulence modulation, non-Newtonian rheology, etc. Over the last few decades, experiments in particle-laden flows have taken a back seat in favour of ever-improving computational resources. However, computers are still not powerful enough to simulate a real-world fluid with millions of finite-size particles. Experiments are essential not only because they offer a reliable way to investigate real-world multiphase flows but also because they serve to validate numerical studies and steer the research in a relevant direction. In this work, we have experimentally investigated particle-laden flows in pipes, and in particular, examined the effect of particles on the laminar-turbulent transition and the drag scaling in turbulent flows.\r\n\r\nFor particle-laden pipe flows, an earlier study [Matas et al., 2003] reported how the sub-critical (i.e., hysteretic) transition that occurs via localised turbulent structures called puffs is affected by the addition of particles. In this study, in addition to this known transition, we found a super-critical transition to a globally fluctuating state with increasing particle concentration. At the same time, the Newtonian-type transition via puffs is delayed to larger Reynolds numbers. At an even higher concentration, only the globally fluctuating state is found. The dynamics of particle-laden flows are hence determined by two competing instabilities that give rise to three flow regimes: Newtonian-type turbulence at low, a particle-induced globally fluctuating state at high, and a coexistence state at intermediate concentrations.\r\n\r\nThe effect of particles on turbulent drag is ambiguous, with studies reporting drag reduction, no net change, and even drag increase. The ambiguity arises because, in addition to particle concentration, particle shape, size, and density also affect the net drag. Even similar particles might affect the flow dissimilarly in different Reynolds number and concentration ranges. In the present study, we explored a wide range of both Reynolds number and concentration, using spherical as well as cylindrical particles. We found that the spherical particles do not reduce drag while the cylindrical particles are drag-reducing within a specific Reynolds number interval. The interval strongly depends on the particle concentration and the relative size of the pipe and particles. Within this interval, the magnitude of drag reduction reaches a maximum. These drag reduction maxima appear to fall onto a distinct power-law curve irrespective of the pipe diameter and particle concentration, and this curve can be considered as the maximum drag reduction asymptote for a given fibre shape. Such an asymptote is well known for polymeric flows but had not been identified for particle-laden flows prior to this work." acknowledged_ssus: - _id: M-Shop alternative_title: - ISTA Thesis article_processing_charge: No author: - first_name: Nishchal full_name: Agrawal, Nishchal id: 469E6004-F248-11E8-B48F-1D18A9856A87 last_name: Agrawal citation: ama: Agrawal N. Transition to turbulence and drag reduction in particle-laden pipe flows. 2021. doi:10.15479/at:ista:9728 apa: Agrawal, N. (2021). Transition to turbulence and drag reduction in particle-laden pipe flows. Institute of Science and Technology Austria. https://doi.org/10.15479/at:ista:9728 chicago: Agrawal, Nishchal. “Transition to Turbulence and Drag Reduction in Particle-Laden Pipe Flows.” Institute of Science and Technology Austria, 2021. https://doi.org/10.15479/at:ista:9728. ieee: N. Agrawal, “Transition to turbulence and drag reduction in particle-laden pipe flows,” Institute of Science and Technology Austria, 2021. ista: Agrawal N. 2021. Transition to turbulence and drag reduction in particle-laden pipe flows. Institute of Science and Technology Austria. mla: Agrawal, Nishchal. Transition to Turbulence and Drag Reduction in Particle-Laden Pipe Flows. Institute of Science and Technology Austria, 2021, doi:10.15479/at:ista:9728. short: N. Agrawal, Transition to Turbulence and Drag Reduction in Particle-Laden Pipe Flows, Institute of Science and Technology Austria, 2021. corr_author: '1' date_created: 2021-07-27T13:40:30Z date_published: 2021-07-29T00:00:00Z date_updated: 2026-04-16T08:43:20Z day: '29' ddc: - '532' degree_awarded: PhD department: - _id: GradSch - _id: BjHo doi: 10.15479/at:ista:9728 file: - access_level: closed checksum: 77436be3563a90435024307b1b5ee7e8 content_type: application/x-zip-compressed creator: nagrawal date_created: 2021-07-28T13:32:02Z date_updated: 2022-07-29T22:30:05Z embargo_to: open_access file_id: '9744' file_name: Transition to Turbulence and Drag Reduction in Particle-Laden Pipe Flows.zip file_size: 22859658 relation: source_file - access_level: open_access checksum: 72a891d7daba85445c29b868c22575ed content_type: application/pdf creator: nagrawal date_created: 2021-07-28T13:32:05Z date_updated: 2022-07-29T22:30:05Z embargo: 2022-07-28 file_id: '9745' file_name: Transition to Turbulence and Drag Reduction in Particle-Laden Pipe Flows.pdf file_size: 18658048 relation: main_file file_date_updated: 2022-07-29T22:30:05Z fulldoi: https://doi.org/10.15479/at:ista:9728 has_accepted_license: '1' keyword: - Drag Reduction - Transition to Turbulence - Multiphase Flows - particle Laden Flows - Complex Flows - Experiments - Fluid Dynamics language: - iso: eng month: '07' oa: 1 oa_version: Published Version page: '118' publication_identifier: issn: - 2663-337X publication_status: published publisher: Institute of Science and Technology Austria related_material: record: - id: '6189' relation: part_of_dissertation status: public status: public supervisor: - first_name: Björn full_name: Hof, Björn id: 3A374330-F248-11E8-B48F-1D18A9856A87 last_name: Hof orcid: 0000-0003-2057-2754 title: Transition to turbulence and drag reduction in particle-laden pipe flows tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: dissertation user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd year: '2021' ... --- _id: '10077' abstract: - lang: eng text: Although much is known about how single neurons in the hippocampus represent an animal’s position, how cell-cell interactions contribute to spatial coding remains poorly understood. Using a novel statistical estimator and theoretical modeling, both developed in the framework of maximum entropy models, we reveal highly structured cell-to-cell interactions whose statistics depend on familiar vs. novel environment. In both conditions the circuit interactions optimize the encoding of spatial information, but for regimes that differ in the signal-to-noise ratio of their spatial inputs. Moreover, the topology of the interactions facilitates linear decodability, making the information easy to read out by downstream circuits. These findings suggest that the efficient coding hypothesis is not applicable only to individual neuron properties in the sensory periphery, but also to neural interactions in the central brain. acknowledgement: We thank Peter Baracskay, Karola Kaefer and Hugo Malagon-Vina for the acquisition of the data. We thank Federico Stella for comments on an earlier version of the manuscript. MN was supported by European Union Horizon 2020 grant 665385, JC was supported by European Research Council consolidator grant 281511, GT was supported by the Austrian Science Fund (FWF) grant P34015, CS was supported by an IST fellow grant, National Institute of Mental Health Award 1R01MH125571-01, by the National Science Foundation under NSF Award No. 1922658 and a Google faculty award. article_processing_charge: No author: - first_name: Michele full_name: Nardin, Michele id: 30BD0376-F248-11E8-B48F-1D18A9856A87 last_name: Nardin orcid: 0000-0001-8849-6570 - first_name: Jozsef L full_name: Csicsvari, Jozsef L id: 3FA14672-F248-11E8-B48F-1D18A9856A87 last_name: Csicsvari orcid: 0000-0002-5193-4036 - first_name: Gašper full_name: Tkačik, Gašper id: 3D494DCA-F248-11E8-B48F-1D18A9856A87 last_name: Tkačik orcid: 0000-0002-6699-1455 - first_name: Cristina full_name: Savin, Cristina id: 3933349E-F248-11E8-B48F-1D18A9856A87 last_name: Savin citation: ama: Nardin M, Csicsvari JL, Tkačik G, Savin C. The structure of hippocampal CA1 interactions optimizes spatial coding across experience. bioRxiv. doi:10.1101/2021.09.28.460602 apa: Nardin, M., Csicsvari, J. L., Tkačik, G., & Savin, C. (n.d.). The structure of hippocampal CA1 interactions optimizes spatial coding across experience. bioRxiv. https://doi.org/10.1101/2021.09.28.460602 chicago: Nardin, Michele, Jozsef L Csicsvari, Gašper Tkačik, and Cristina Savin. “The Structure of Hippocampal CA1 Interactions Optimizes Spatial Coding across Experience.” BioRxiv, n.d. https://doi.org/10.1101/2021.09.28.460602. ieee: M. Nardin, J. L. Csicsvari, G. Tkačik, and C. Savin, “The structure of hippocampal CA1 interactions optimizes spatial coding across experience,” bioRxiv. . ista: Nardin M, Csicsvari JL, Tkačik G, Savin C. The structure of hippocampal CA1 interactions optimizes spatial coding across experience. bioRxiv, 10.1101/2021.09.28.460602. mla: Nardin, Michele, et al. “The Structure of Hippocampal CA1 Interactions Optimizes Spatial Coding across Experience.” BioRxiv, doi:10.1101/2021.09.28.460602. short: M. Nardin, J.L. Csicsvari, G. Tkačik, C. Savin, BioRxiv (n.d.). das_tickbox: '1' date_created: 2021-10-04T06:23:34Z date_published: 2021-09-29T00:00:00Z date_updated: 2026-11-12T23:30:26Z day: '29' department: - _id: GradSch - _id: JoCs - _id: GaTk doi: 10.1101/2021.09.28.460602 ec_funded: 1 fulldoi: https://doi.org/10.1101/2021.09.28.460602 language: - iso: eng main_file_link: - open_access: '1' url: https://www.biorxiv.org/content/10.1101/2021.09.28.460602 month: '09' oa: 1 oa_version: Preprint project: - _id: 25681D80-B435-11E9-9278-68D0E5697425 call_identifier: FP7 grant_number: '291734' name: International IST Postdoc Fellowship Programme - _id: 2564DBCA-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '665385' name: International IST Doctoral Program - _id: 257A4776-B435-11E9-9278-68D0E5697425 call_identifier: FP7 grant_number: '281511' name: Memory-related information processing in neuronal circuits of the hippocampus and entorhinal cortex - _id: 626c45b5-2b32-11ec-9570-e509828c1ba6 grant_number: P34015 name: Efficient coding with biophysical realism publication: bioRxiv publication_status: draft related_material: record: - id: '11932' relation: dissertation_contains status: public - id: '14656' relation: later_version status: public status: public title: The structure of hippocampal CA1 interactions optimizes spatial coding across experience tmp: image: /images/cc_by_nc_nd.png legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) short: CC BY-NC-ND (4.0) type: preprint user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2021' ...