---
_id: '11898'
abstract:
- lang: eng
text: "We build upon the recent papers by Weinstein and Yu (FOCS'16), Larsen (FOCS'12),
and Clifford et al. (FOCS'15) to present a general framework that gives amortized
lower bounds on the update and query times of dynamic data structures. Using our
framework, we present two concrete results.\r\n(1) For the dynamic polynomial
evaluation problem, where the polynomial is defined over a finite field of size
n1+Ω(1) and has degree n, any dynamic data structure must either have an amortized
update time of Ω((lgn/lglgn)2) or an amortized query time of Ω((lgn/lglgn)2).\r\n(2)
For the dynamic online matrix vector multiplication problem, where we get an n×n
matrix whose entires are drawn from a finite field of size nΘ(1), any dynamic
data structure must either have an amortized update time of Ω((lgn/lglgn)2) or
an amortized query time of Ω(n⋅(lgn/lglgn)2).\r\nFor these two problems, the previous
works by Larsen (FOCS'12) and Clifford et al. (FOCS'15) gave the same lower bounds,
but only for worst case update and query times. Our bounds match the highest unconditional
lower bounds known till date for any dynamic problem in the cell-probe model."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Sayan
full_name: Bhattacharya, Sayan
last_name: Bhattacharya
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Stefan
full_name: Neumann, Stefan
last_name: Neumann
citation:
ama: Bhattacharya S, Henzinger M, Neumann S. New amortized cell-probe lower bounds
for dynamic problems. Theoretical Computer Science. 2019;779:72-87. doi:10.1016/j.tcs.2019.01.043
apa: Bhattacharya, S., Henzinger, M., & Neumann, S. (2019). New amortized cell-probe
lower bounds for dynamic problems. Theoretical Computer Science. Elsevier.
https://doi.org/10.1016/j.tcs.2019.01.043
chicago: Bhattacharya, Sayan, Monika Henzinger, and Stefan Neumann. “New Amortized
Cell-Probe Lower Bounds for Dynamic Problems.” Theoretical Computer Science.
Elsevier, 2019. https://doi.org/10.1016/j.tcs.2019.01.043.
ieee: S. Bhattacharya, M. Henzinger, and S. Neumann, “New amortized cell-probe lower
bounds for dynamic problems,” Theoretical Computer Science, vol. 779. Elsevier,
pp. 72–87, 2019.
ista: Bhattacharya S, Henzinger M, Neumann S. 2019. New amortized cell-probe lower
bounds for dynamic problems. Theoretical Computer Science. 779, 72–87.
mla: Bhattacharya, Sayan, et al. “New Amortized Cell-Probe Lower Bounds for Dynamic
Problems.” Theoretical Computer Science, vol. 779, Elsevier, 2019, pp.
72–87, doi:10.1016/j.tcs.2019.01.043.
short: S. Bhattacharya, M. Henzinger, S. Neumann, Theoretical Computer Science 779
(2019) 72–87.
date_created: 2022-08-17T09:02:15Z
date_published: 2019-08-02T00:00:00Z
date_updated: 2024-11-06T12:23:49Z
day: '02'
doi: 10.1016/j.tcs.2019.01.043
extern: '1'
external_id:
arxiv:
- '1902.02304'
intvolume: ' 779'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1902.02304
month: '08'
oa: 1
oa_version: Preprint
page: 72-87
publication: Theoretical Computer Science
publication_identifier:
issn:
- 0304-3975
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: New amortized cell-probe lower bounds for dynamic problems
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 779
year: '2019'
...
---
_id: '11957'
abstract:
- lang: eng
text: Cross-coupling reactions mediated by dual nickel/photocatalysis are synthetically
attractive but rely mainly on expensive, non-recyclable noble-metal complexes
as photocatalysts. Heterogeneous semiconductors, which are commonly used for artificial
photosynthesis and wastewater treatment, are a sustainable alternative. Graphitic
carbon nitrides, a class of metal-free polymers that can be easily prepared from
bulk chemicals, are heterogeneous semiconductors with high potential for photocatalytic
organic transformations. Here, we demonstrate that graphitic carbon nitrides in
combination with nickel catalysis can induce selective C−O cross-couplings of
carboxylic acids with aryl halides, yielding the respective aryl esters in excellent
yield and selectivity. The heterogeneous organic photocatalyst exhibits a broad
substrate scope, is able to harvest green light, and can be recycled multiple
times. In situ FTIR was used to track the reaction progress to study this transformation
at different irradiation wavelengths and reaction scales.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Bartholomäus
full_name: Pieber, Bartholomäus
id: 93e5e5b2-0da6-11ed-8a41-af589a024726
last_name: Pieber
orcid: 0000-0001-8689-388X
- first_name: Jamal A.
full_name: Malik, Jamal A.
last_name: Malik
- first_name: Cristian
full_name: Cavedon, Cristian
last_name: Cavedon
- first_name: Sebastian
full_name: Gisbertz, Sebastian
last_name: Gisbertz
- first_name: Aleksandr
full_name: Savateev, Aleksandr
last_name: Savateev
- first_name: Daniel
full_name: Cruz, Daniel
last_name: Cruz
- first_name: Tobias
full_name: Heil, Tobias
last_name: Heil
- first_name: Guigang
full_name: Zhang, Guigang
last_name: Zhang
- first_name: Peter H.
full_name: Seeberger, Peter H.
last_name: Seeberger
citation:
ama: 'Pieber B, Malik JA, Cavedon C, et al. Semi‐heterogeneous dual nickel/photocatalysis
using carbon nitrides: Esterification of carboxylic acids with aryl halides. Angewandte
Chemie International Edition. 2019;58(28):9575-9580. doi:10.1002/anie.201902785'
apa: 'Pieber, B., Malik, J. A., Cavedon, C., Gisbertz, S., Savateev, A., Cruz, D.,
… Seeberger, P. H. (2019). Semi‐heterogeneous dual nickel/photocatalysis using
carbon nitrides: Esterification of carboxylic acids with aryl halides. Angewandte
Chemie International Edition. Wiley. https://doi.org/10.1002/anie.201902785'
chicago: 'Pieber, Bartholomäus, Jamal A. Malik, Cristian Cavedon, Sebastian Gisbertz,
Aleksandr Savateev, Daniel Cruz, Tobias Heil, Guigang Zhang, and Peter H. Seeberger.
“Semi‐heterogeneous Dual Nickel/Photocatalysis Using Carbon Nitrides: Esterification
of Carboxylic Acids with Aryl Halides.” Angewandte Chemie International Edition.
Wiley, 2019. https://doi.org/10.1002/anie.201902785.'
ieee: 'B. Pieber et al., “Semi‐heterogeneous dual nickel/photocatalysis using
carbon nitrides: Esterification of carboxylic acids with aryl halides,” Angewandte
Chemie International Edition, vol. 58, no. 28. Wiley, pp. 9575–9580, 2019.'
ista: 'Pieber B, Malik JA, Cavedon C, Gisbertz S, Savateev A, Cruz D, Heil T, Zhang
G, Seeberger PH. 2019. Semi‐heterogeneous dual nickel/photocatalysis using carbon
nitrides: Esterification of carboxylic acids with aryl halides. Angewandte Chemie
International Edition. 58(28), 9575–9580.'
mla: 'Pieber, Bartholomäus, et al. “Semi‐heterogeneous Dual Nickel/Photocatalysis
Using Carbon Nitrides: Esterification of Carboxylic Acids with Aryl Halides.”
Angewandte Chemie International Edition, vol. 58, no. 28, Wiley, 2019,
pp. 9575–80, doi:10.1002/anie.201902785.'
short: B. Pieber, J.A. Malik, C. Cavedon, S. Gisbertz, A. Savateev, D. Cruz, T.
Heil, G. Zhang, P.H. Seeberger, Angewandte Chemie International Edition 58 (2019)
9575–9580.
date_created: 2022-08-24T10:50:19Z
date_published: 2019-07-08T00:00:00Z
date_updated: 2024-10-14T11:43:18Z
day: '08'
doi: 10.1002/anie.201902785
extern: '1'
external_id:
pmid:
- '31050132'
intvolume: ' 58'
issue: '28'
language:
- iso: eng
month: '07'
oa_version: None
page: 9575-9580
pmid: 1
publication: Angewandte Chemie International Edition
publication_identifier:
eissn:
- 1521-3773
issn:
- 1433-7851
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Semi‐heterogeneous dual nickel/photocatalysis using carbon nitrides: Esterification
of carboxylic acids with aryl halides'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 58
year: '2019'
...
---
_id: '11982'
abstract:
- lang: eng
text: A carbon nitride material can be combined with homogeneous nickel catalysts
for light-mediated cross-couplings of aryl bromides with alcohols under mild conditions.
The metal-free heterogeneous semiconductor is fully recyclable and couples a broad
range of electron-poor aryl bromides with primary and secondary alcohols as well
as water. The application for intramolecular reactions and the synthesis of active
pharmaceutical ingredients was demonstrated. The catalytic protocol is applicable
for the coupling of aryl iodides with thiols as well.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Cristian
full_name: Cavedon, Cristian
last_name: Cavedon
- first_name: Amiera
full_name: Madani, Amiera
last_name: Madani
- first_name: Peter H.
full_name: Seeberger, Peter H.
last_name: Seeberger
- first_name: Bartholomäus
full_name: Pieber, Bartholomäus
id: 93e5e5b2-0da6-11ed-8a41-af589a024726
last_name: Pieber
orcid: 0000-0001-8689-388X
citation:
ama: Cavedon C, Madani A, Seeberger PH, Pieber B. Semiheterogeneous dual nickel/photocatalytic
(thio)etherification using carbon nitrides. Organic Letters. 2019;21(13):5331-5334.
doi:10.1021/acs.orglett.9b01957
apa: Cavedon, C., Madani, A., Seeberger, P. H., & Pieber, B. (2019). Semiheterogeneous
dual nickel/photocatalytic (thio)etherification using carbon nitrides. Organic
Letters. American Chemical Society. https://doi.org/10.1021/acs.orglett.9b01957
chicago: Cavedon, Cristian, Amiera Madani, Peter H. Seeberger, and Bartholomäus
Pieber. “Semiheterogeneous Dual Nickel/Photocatalytic (Thio)Etherification Using
Carbon Nitrides.” Organic Letters. American Chemical Society, 2019. https://doi.org/10.1021/acs.orglett.9b01957.
ieee: C. Cavedon, A. Madani, P. H. Seeberger, and B. Pieber, “Semiheterogeneous
dual nickel/photocatalytic (thio)etherification using carbon nitrides,” Organic
Letters, vol. 21, no. 13. American Chemical Society, pp. 5331–5334, 2019.
ista: Cavedon C, Madani A, Seeberger PH, Pieber B. 2019. Semiheterogeneous dual
nickel/photocatalytic (thio)etherification using carbon nitrides. Organic Letters.
21(13), 5331–5334.
mla: Cavedon, Cristian, et al. “Semiheterogeneous Dual Nickel/Photocatalytic (Thio)Etherification
Using Carbon Nitrides.” Organic Letters, vol. 21, no. 13, American Chemical
Society, 2019, pp. 5331–34, doi:10.1021/acs.orglett.9b01957.
short: C. Cavedon, A. Madani, P.H. Seeberger, B. Pieber, Organic Letters 21 (2019)
5331–5334.
date_created: 2022-08-25T11:18:00Z
date_published: 2019-07-05T00:00:00Z
date_updated: 2024-10-14T12:07:10Z
day: '05'
doi: 10.1021/acs.orglett.9b01957
extern: '1'
external_id:
pmid:
- '31247752'
intvolume: ' 21'
issue: '13'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1021/acs.orglett.9b01957
month: '07'
oa: 1
oa_version: Published Version
page: 5331-5334
pmid: 1
publication: Organic Letters
publication_identifier:
eissn:
- 1523-7052
issn:
- 1523-7060
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Semiheterogeneous dual nickel/photocatalytic (thio)etherification using carbon
nitrides
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 21
year: '2019'
...
---
_id: '11984'
abstract:
- lang: eng
text: Differentially protected galactosamine building blocks are key components
for the synthesis of human and bacterial oligosaccharides. The azidophenylselenylation
of 3,4,6-tri-O-acetyl-d-galactal provides straightforward access to the corresponding
2-nitrogenated glycoside. Poor reproducibility and the use of azides that lead
to the formation of potentially explosive and toxic species limit the scalability
of this reaction and render it a bottleneck for carbohydrate synthesis. Here,
we present a method for the safe, efficient, and reliable azidophenylselenylation
of 3,4,6-tri-O-acetyl-d-galactal at room temperature, using continuous flow chemistry.
Careful analysis of the transformation resulted in reaction conditions that produce
minimal side products while the reaction time was reduced drastically when compared
to batch reactions. The flow setup is readily scalable to process 5 mmol of galactal
in 3 h, producing 1.2 mmol/h of product.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Mónica
full_name: Guberman, Mónica
last_name: Guberman
- first_name: Bartholomäus
full_name: Pieber, Bartholomäus
id: 93e5e5b2-0da6-11ed-8a41-af589a024726
last_name: Pieber
orcid: 0000-0001-8689-388X
- first_name: Peter H.
full_name: Seeberger, Peter H.
last_name: Seeberger
citation:
ama: Guberman M, Pieber B, Seeberger PH. Safe and scalable continuous flow azidophenylselenylation
of galactal to prepare galactosamine building blocks. Organic Process Research
and Development. 2019;23(12):2764-2770. doi:10.1021/acs.oprd.9b00456
apa: Guberman, M., Pieber, B., & Seeberger, P. H. (2019). Safe and scalable
continuous flow azidophenylselenylation of galactal to prepare galactosamine building
blocks. Organic Process Research and Development. American Chemical Society.
https://doi.org/10.1021/acs.oprd.9b00456
chicago: Guberman, Mónica, Bartholomäus Pieber, and Peter H. Seeberger. “Safe and
Scalable Continuous Flow Azidophenylselenylation of Galactal to Prepare Galactosamine
Building Blocks.” Organic Process Research and Development. American Chemical
Society, 2019. https://doi.org/10.1021/acs.oprd.9b00456.
ieee: M. Guberman, B. Pieber, and P. H. Seeberger, “Safe and scalable continuous
flow azidophenylselenylation of galactal to prepare galactosamine building blocks,”
Organic Process Research and Development, vol. 23, no. 12. American Chemical
Society, pp. 2764–2770, 2019.
ista: Guberman M, Pieber B, Seeberger PH. 2019. Safe and scalable continuous flow
azidophenylselenylation of galactal to prepare galactosamine building blocks.
Organic Process Research and Development. 23(12), 2764–2770.
mla: Guberman, Mónica, et al. “Safe and Scalable Continuous Flow Azidophenylselenylation
of Galactal to Prepare Galactosamine Building Blocks.” Organic Process Research
and Development, vol. 23, no. 12, American Chemical Society, 2019, pp. 2764–70,
doi:10.1021/acs.oprd.9b00456.
short: M. Guberman, B. Pieber, P.H. Seeberger, Organic Process Research and Development
23 (2019) 2764–2770.
date_created: 2022-08-25T11:30:33Z
date_published: 2019-12-20T00:00:00Z
date_updated: 2023-02-21T10:10:23Z
day: '20'
doi: 10.1021/acs.oprd.9b00456
extern: '1'
intvolume: ' 23'
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1021/acs.oprd.9b00456
month: '12'
oa: 1
oa_version: Published Version
page: 2764-2770
publication: Organic Process Research and Development
publication_identifier:
eissn:
- 1520-586X
issn:
- 1083-6160
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Safe and scalable continuous flow azidophenylselenylation of galactal to prepare
galactosamine building blocks
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 23
year: '2019'
...
---
OA_place: repository
OA_type: green
_id: '22028'
abstract:
- lang: eng
text: "We prove global well-posedness of the Korteweg–de Vries equation for\r\ninitial
data in the space H^−1(R). This is sharp in the class of H^s(R) spaces.\r\nEven
local well-posedness was previously unknown for s < −3/4. The proof\r\nis based
on the introduction of a new method of general applicability for the\r\nstudy
of low-regularity well-posedness for integrable PDE, informed by the\r\nexistence
of commuting flows. In particular, as we will show, completely\r\nparallel arguments
give a new proof of global well-posedness for KdV with\r\nperiodic H−1 data, shown
previously by Kappeler and Topalov, as well as\r\nglobal well-posedness for the
fifth order KdV equation in L^2(R).\r\nAdditionally, we give a new proof of the
a priori local smoothing bound\r\nof Buckmaster and Koch for KdV on the line.
Moreover, we upgrade this\r\nestimate to show that convergence of initial data
in H^−1(R) guarantees\r\nconvergence of the resulting solutions in L^2loc(R ×
R). Thus, solutions with\r\nH^−1(R) initial data are distributional solutions."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Rowan
full_name: Killip, Rowan
last_name: Killip
- first_name: Monica
full_name: Visan, Monica
id: 056daca0-b8d1-11f0-964f-f91054abf8ca
last_name: Visan
citation:
ama: Killip R, Vişan M. KdV is well-posed in H^-1. Annals of Mathematics.
2019;190(1):249-305. doi:10.4007/annals.2019.190.1.4
apa: Killip, R., & Vişan, M. (2019). KdV is well-posed in H^-1. Annals of
Mathematics. Annals of Mathematics. https://doi.org/10.4007/annals.2019.190.1.4
chicago: Killip, Rowan, and Monica Vişan. “KdV Is Well-Posed in H^-1.” Annals
of Mathematics. Annals of Mathematics, 2019. https://doi.org/10.4007/annals.2019.190.1.4.
ieee: R. Killip and M. Vişan, “KdV is well-posed in H^-1,” Annals of Mathematics,
vol. 190, no. 1. Annals of Mathematics, pp. 249–305, 2019.
ista: Killip R, Vişan M. 2019. KdV is well-posed in H^-1. Annals of Mathematics.
190(1), 249–305.
mla: Killip, Rowan, and Monica Vişan. “KdV Is Well-Posed in H^-1.” Annals of
Mathematics, vol. 190, no. 1, Annals of Mathematics, 2019, pp. 249–305, doi:10.4007/annals.2019.190.1.4.
short: R. Killip, M. Vişan, Annals of Mathematics 190 (2019) 249–305.
das_tickbox: '1'
date_created: 2026-06-19T07:37:37Z
date_published: 2019-07-05T00:00:00Z
date_updated: 2026-06-22T11:12:40Z
day: '05'
doi: 10.4007/annals.2019.190.1.4
extern: '1'
external_id:
arxiv:
- '1802.04851'
intvolume: ' 190'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.1802.04851
month: '07'
oa: 1
oa_version: Preprint
page: 249-305
publication: Annals of Mathematics
publication_identifier:
issn:
- 0003-486X
publication_status: published
publisher: Annals of Mathematics
quality_controlled: '1'
scopus_import: '1'
status: public
title: KdV is well-posed in H^-1
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 190
year: '2019'
...
---
OA_place: repository
OA_type: green
_id: '22030'
abstract:
- lang: eng
text: We consider the mass-subcritical NLS in dimensions d>=3 with radial initial
data. In the defocusing case, we prove that any solution that remains bounded
in the critical Sobolev space throughout its lifespan must be global and scatter.
In the focusing case, we prove the existence of a threshold solution that has
a compact flow.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Rowan
full_name: Killip, Rowan
last_name: Killip
- first_name: Satoshi
full_name: Masaki, Satoshi
last_name: Masaki
- first_name: Jason
full_name: Murphy, Jason
last_name: Murphy
- first_name: Monica
full_name: Visan, Monica
id: 056daca0-b8d1-11f0-964f-f91054abf8ca
last_name: Visan
citation:
ama: Killip R, Masaki S, Murphy J, Vişan M. The radial mass-subcritical NLS in negative
order Sobolev spaces. Discrete and Continuous Dynamical Systems. 2019;39(1):553-583.
doi:10.3934/dcds.2019023
apa: Killip, R., Masaki, S., Murphy, J., & Vişan, M. (2019). The radial mass-subcritical
NLS in negative order Sobolev spaces. Discrete and Continuous Dynamical Systems.
American Institute of Mathematical Sciences. https://doi.org/10.3934/dcds.2019023
chicago: Killip, Rowan, Satoshi Masaki, Jason Murphy, and Monica Vişan. “The Radial
Mass-Subcritical NLS in Negative Order Sobolev Spaces.” Discrete and Continuous
Dynamical Systems. American Institute of Mathematical Sciences, 2019. https://doi.org/10.3934/dcds.2019023.
ieee: R. Killip, S. Masaki, J. Murphy, and M. Vişan, “The radial mass-subcritical
NLS in negative order Sobolev spaces,” Discrete and Continuous Dynamical Systems,
vol. 39, no. 1. American Institute of Mathematical Sciences, pp. 553–583, 2019.
ista: Killip R, Masaki S, Murphy J, Vişan M. 2019. The radial mass-subcritical NLS
in negative order Sobolev spaces. Discrete and Continuous Dynamical Systems. 39(1),
553–583.
mla: Killip, Rowan, et al. “The Radial Mass-Subcritical NLS in Negative Order Sobolev
Spaces.” Discrete and Continuous Dynamical Systems, vol. 39, no. 1, American
Institute of Mathematical Sciences, 2019, pp. 553–83, doi:10.3934/dcds.2019023.
short: R. Killip, S. Masaki, J. Murphy, M. Vişan, Discrete and Continuous Dynamical
Systems 39 (2019) 553–583.
das_tickbox: '1'
date_created: 2026-06-19T07:41:46Z
date_published: 2019-01-01T00:00:00Z
date_updated: 2026-06-22T11:06:54Z
day: '01'
doi: 10.3934/dcds.2019023
extern: '1'
external_id:
arxiv:
- '1804.06753'
intvolume: ' 39'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.1804.06753
month: '01'
oa: 1
oa_version: Preprint
page: 553-583
publication: Discrete and Continuous Dynamical Systems
publication_identifier:
eissn:
- 1553-5231
issn:
- 1078-0947
publication_status: published
publisher: American Institute of Mathematical Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: The radial mass-subcritical NLS in negative order Sobolev spaces
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 39
year: '2019'
...
---
_id: '27'
abstract:
- lang: eng
text: The cerebral cortex is composed of a large variety of distinct cell-types
including projection neurons, interneurons and glial cells which emerge from distinct
neural stem cell (NSC) lineages. The vast majority of cortical projection neurons
and certain classes of glial cells are generated by radial glial progenitor cells
(RGPs) in a highly orchestrated manner. Recent studies employing single cell analysis
and clonal lineage tracing suggest that NSC and RGP lineage progression are regulated
in a profound deterministic manner. In this review we focus on recent advances
based mainly on correlative phenotypic data emerging from functional genetic studies
in mice. We establish hypotheses to test in future research and outline a conceptual
framework how epigenetic cues modulate the generation of cell-type diversity during
cortical development. This article is protected by copyright. All rights reserved.
acknowledgement: " This work was supported by IST Austria institutional funds; NÖ
Forschung und Bildung \r\nn[f+b] (C13-002) to SH; a program grant from
\ the Human Frontiers Science Program (RGP0053/2014) to SH; the People
\ Programme (Marie Curie Actions) of the European Union’s Seventh Framework
Programme (FP7/2007-2013) under REA grant agreement No 618444 to SH, and the European
\ Research Council (ERC) under the European Union’s Horizon 2020 research
\ and innovation programme (grant agreement No 725780 LinPro)to SH.\r\n"
article_processing_charge: Yes (via OA deal)
article_type: review
author:
- first_name: Nicole
full_name: Amberg, Nicole
id: 4CD6AAC6-F248-11E8-B48F-1D18A9856A87
last_name: Amberg
orcid: 0000-0002-3183-8207
- first_name: Susanne
full_name: Laukoter, Susanne
id: 2D6B7A9A-F248-11E8-B48F-1D18A9856A87
last_name: Laukoter
orcid: 0000-0002-7903-3010
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
citation:
ama: Amberg N, Laukoter S, Hippenmeyer S. Epigenetic cues modulating the generation
of cell type diversity in the cerebral cortex. Journal of Neurochemistry.
2019;149(1):12-26. doi:10.1111/jnc.14601
apa: Amberg, N., Laukoter, S., & Hippenmeyer, S. (2019). Epigenetic cues modulating
the generation of cell type diversity in the cerebral cortex. Journal of Neurochemistry.
Wiley. https://doi.org/10.1111/jnc.14601
chicago: Amberg, Nicole, Susanne Laukoter, and Simon Hippenmeyer. “Epigenetic Cues
Modulating the Generation of Cell Type Diversity in the Cerebral Cortex.” Journal
of Neurochemistry. Wiley, 2019. https://doi.org/10.1111/jnc.14601.
ieee: N. Amberg, S. Laukoter, and S. Hippenmeyer, “Epigenetic cues modulating the
generation of cell type diversity in the cerebral cortex,” Journal of Neurochemistry,
vol. 149, no. 1. Wiley, pp. 12–26, 2019.
ista: Amberg N, Laukoter S, Hippenmeyer S. 2019. Epigenetic cues modulating the
generation of cell type diversity in the cerebral cortex. Journal of Neurochemistry.
149(1), 12–26.
mla: Amberg, Nicole, et al. “Epigenetic Cues Modulating the Generation of Cell Type
Diversity in the Cerebral Cortex.” Journal of Neurochemistry, vol. 149,
no. 1, Wiley, 2019, pp. 12–26, doi:10.1111/jnc.14601.
short: N. Amberg, S. Laukoter, S. Hippenmeyer, Journal of Neurochemistry 149 (2019)
12–26.
corr_author: '1'
date_created: 2018-12-11T11:44:14Z
date_published: 2019-04-01T00:00:00Z
date_updated: 2025-04-14T07:43:05Z
day: '01'
ddc:
- '570'
department:
- _id: SiHi
doi: 10.1111/jnc.14601
ec_funded: 1
external_id:
isi:
- '000462680200002'
file:
- access_level: open_access
checksum: db027721a95d36f5de36aadcd0bdf7e6
content_type: application/pdf
creator: kschuh
date_created: 2020-01-07T13:35:52Z
date_updated: 2020-07-14T12:45:45Z
file_id: '7239'
file_name: 2019_Wiley_Amberg.pdf
file_size: 889709
relation: main_file
file_date_updated: 2020-07-14T12:45:45Z
has_accepted_license: '1'
intvolume: ' 149'
isi: 1
issue: '1'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 12-26
project:
- _id: 25D92700-B435-11E9-9278-68D0E5697425
grant_number: LS13-002
name: Mapping Cell-Type Specificity of the Genomic Imprintome in the Brain
- _id: 25D7962E-B435-11E9-9278-68D0E5697425
grant_number: RGP0053/2014
name: Quantitative Structure-Function Analysis of Cerebral Cortex Assembly at Clonal
Level
- _id: 25D61E48-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '618444'
name: Molecular Mechanisms of Cerebral Cortex Development
- _id: 260018B0-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '725780'
name: Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development
publication: Journal of Neurochemistry
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Epigenetic cues modulating the generation of cell type diversity in the cerebral
cortex
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 149
year: '2019'
...
---
_id: '301'
abstract:
- lang: eng
text: A representation formula for solutions of stochastic partial differential
equations with Dirichlet boundary conditions is proved. The scope of our setting
is wide enough to cover the general situation when the backward characteristics
that appear in the usual formulation are not even defined in the Itô sense.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Mate
full_name: Gerencser, Mate
id: 44ECEDF2-F248-11E8-B48F-1D18A9856A87
last_name: Gerencser
- first_name: István
full_name: Gyöngy, István
last_name: Gyöngy
citation:
ama: Gerencser M, Gyöngy I. A Feynman–Kac formula for stochastic Dirichlet problems.
Stochastic Processes and their Applications. 2019;129(3):995-1012. doi:10.1016/j.spa.2018.04.003
apa: Gerencser, M., & Gyöngy, I. (2019). A Feynman–Kac formula for stochastic
Dirichlet problems. Stochastic Processes and Their Applications. Elsevier.
https://doi.org/10.1016/j.spa.2018.04.003
chicago: Gerencser, Mate, and István Gyöngy. “A Feynman–Kac Formula for Stochastic
Dirichlet Problems.” Stochastic Processes and Their Applications. Elsevier,
2019. https://doi.org/10.1016/j.spa.2018.04.003.
ieee: M. Gerencser and I. Gyöngy, “A Feynman–Kac formula for stochastic Dirichlet
problems,” Stochastic Processes and their Applications, vol. 129, no. 3.
Elsevier, pp. 995–1012, 2019.
ista: Gerencser M, Gyöngy I. 2019. A Feynman–Kac formula for stochastic Dirichlet
problems. Stochastic Processes and their Applications. 129(3), 995–1012.
mla: Gerencser, Mate, and István Gyöngy. “A Feynman–Kac Formula for Stochastic Dirichlet
Problems.” Stochastic Processes and Their Applications, vol. 129, no. 3,
Elsevier, 2019, pp. 995–1012, doi:10.1016/j.spa.2018.04.003.
short: M. Gerencser, I. Gyöngy, Stochastic Processes and Their Applications 129
(2019) 995–1012.
date_created: 2018-12-11T11:45:42Z
date_published: 2019-03-01T00:00:00Z
date_updated: 2023-08-24T14:20:49Z
day: '01'
department:
- _id: JaMa
doi: 10.1016/j.spa.2018.04.003
external_id:
arxiv:
- '1611.04177'
isi:
- '000458945300012'
intvolume: ' 129'
isi: 1
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1611.04177
month: '03'
oa: 1
oa_version: Preprint
page: 995-1012
publication: Stochastic Processes and their Applications
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: A Feynman–Kac formula for stochastic Dirichlet problems
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 129
year: '2019'
...
---
_id: '12190'
abstract:
- lang: eng
text: Meiotic crossover frequency varies within genomes, which influences genetic
diversity and adaptation. In turn, genetic variation within populations can act
to modify crossover frequency in cis and trans. To identify genetic variation
that controls meiotic crossover frequency, we screened Arabidopsis accessions
using fluorescent recombination reporters. We mapped a genetic modifier of crossover
frequency in Col × Bur populations of Arabidopsis to a premature stop codon within
TBP-ASSOCIATED FACTOR 4b (TAF4b), which encodes a subunit of the RNA polymerase
II general transcription factor TFIID. The Arabidopsis taf4b mutation is a rare
variant found in the British Isles, originating in South-West Ireland. Using genetics,
genomics, and immunocytology, we demonstrate a genome-wide decrease in taf4b crossovers,
with strongest reduction in the sub-telomeric regions. Using RNA sequencing (RNA-seq)
from purified meiocytes, we show that TAF4b expression is meiocyte enriched, whereas
its paralog TAF4 is broadly expressed. Consistent with the role of TFIID in promoting
gene expression, RNA-seq of wild-type and taf4b meiocytes identified widespread
transcriptional changes, including in genes that regulate the meiotic cell cycle
and recombination. Therefore, TAF4b duplication is associated with acquisition
of meiocyte-specific expression and promotion of germline transcription, which
act directly or indirectly to elevate crossovers. This identifies a novel mode
of meiotic recombination control via a general transcription factor.
acknowledgement: "We thank Gregory Copenhaver (University of North Carolina), Avraham
Levy (The Weizmann Institute), and Scott Poethig (University of Pennsylvania) for
FTLs; Piotr Ziolkowski for Col-420/Bur seed; Sureshkumar Balasubramanian\r\n(Monash
University) for providing British and Irish Arabidopsis accessions; Mathilde Grelon
(INRA, Versailles) for providing the MLH1 antibody; and the Gurdon Institute for
access to microscopes. This work was supported by a BBSRC DTP studentship (E.J.L.),
European Research Area Network for Coordinating Action in Plant Sciences/BBSRC ‘‘DeCOP’’
(BB/M004937/1; C.L.), a BBSRC David Phillips Fellowship (BB/L025043/1; H.G. and
X.F.), the European Research Council (CoG ‘‘SynthHotspot,’’ A.J.T., C.L., and I.R.H.;
StG ‘‘SexMeth,’’ X.F.), and a Sainsbury Charitable Foundation Studentship (A.R.B.)."
article_processing_charge: No
article_type: original
author:
- first_name: Emma J.
full_name: Lawrence, Emma J.
last_name: Lawrence
- first_name: Hongbo
full_name: Gao, Hongbo
last_name: Gao
- first_name: Andrew J.
full_name: Tock, Andrew J.
last_name: Tock
- first_name: Christophe
full_name: Lambing, Christophe
last_name: Lambing
- first_name: Alexander R.
full_name: Blackwell, Alexander R.
last_name: Blackwell
- first_name: Xiaoqi
full_name: Feng, Xiaoqi
id: e0164712-22ee-11ed-b12a-d80fcdf35958
last_name: Feng
orcid: 0000-0002-4008-1234
- first_name: Ian R.
full_name: Henderson, Ian R.
last_name: Henderson
citation:
ama: Lawrence EJ, Gao H, Tock AJ, et al. Natural variation in TBP-ASSOCIATED FACTOR
4b controls meiotic crossover and germline transcription in Arabidopsis. Current
Biology. 2019;29(16):2676-2686.e3. doi:10.1016/j.cub.2019.06.084
apa: Lawrence, E. J., Gao, H., Tock, A. J., Lambing, C., Blackwell, A. R., Feng,
X., & Henderson, I. R. (2019). Natural variation in TBP-ASSOCIATED FACTOR
4b controls meiotic crossover and germline transcription in Arabidopsis. Current
Biology. Elsevier. https://doi.org/10.1016/j.cub.2019.06.084
chicago: Lawrence, Emma J., Hongbo Gao, Andrew J. Tock, Christophe Lambing, Alexander
R. Blackwell, Xiaoqi Feng, and Ian R. Henderson. “Natural Variation in TBP-ASSOCIATED
FACTOR 4b Controls Meiotic Crossover and Germline Transcription in Arabidopsis.”
Current Biology. Elsevier, 2019. https://doi.org/10.1016/j.cub.2019.06.084.
ieee: E. J. Lawrence et al., “Natural variation in TBP-ASSOCIATED FACTOR
4b controls meiotic crossover and germline transcription in Arabidopsis,” Current
Biology, vol. 29, no. 16. Elsevier, p. 2676–2686.e3, 2019.
ista: Lawrence EJ, Gao H, Tock AJ, Lambing C, Blackwell AR, Feng X, Henderson IR.
2019. Natural variation in TBP-ASSOCIATED FACTOR 4b controls meiotic crossover
and germline transcription in Arabidopsis. Current Biology. 29(16), 2676–2686.e3.
mla: Lawrence, Emma J., et al. “Natural Variation in TBP-ASSOCIATED FACTOR 4b Controls
Meiotic Crossover and Germline Transcription in Arabidopsis.” Current Biology,
vol. 29, no. 16, Elsevier, 2019, p. 2676–2686.e3, doi:10.1016/j.cub.2019.06.084.
short: E.J. Lawrence, H. Gao, A.J. Tock, C. Lambing, A.R. Blackwell, X. Feng, I.R.
Henderson, Current Biology 29 (2019) 2676–2686.e3.
date_created: 2023-01-16T09:16:33Z
date_published: 2019-08-19T00:00:00Z
date_updated: 2025-01-14T14:31:02Z
day: '19'
department:
- _id: XiFe
doi: 10.1016/j.cub.2019.06.084
extern: '1'
external_id:
pmid:
- '31378616'
intvolume: ' 29'
issue: '16'
keyword:
- General Agricultural and Biological Sciences
- General Biochemistry
- Genetics and Molecular Biology
language:
- iso: eng
month: '08'
oa_version: None
page: 2676-2686.e3
pmid: 1
publication: Current Biology
publication_identifier:
issn:
- 0960-9822
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Natural variation in TBP-ASSOCIATED FACTOR 4b controls meiotic crossover and
germline transcription in Arabidopsis
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 29
year: '2019'
...
---
_id: '12192'
abstract:
- lang: eng
text: Transposable elements (TEs), the movement of which can damage the genome,
are epigenetically silenced in eukaryotes. Intriguingly, TEs are activated in
the sperm companion cell – vegetative cell (VC) – of the flowering plant Arabidopsis
thaliana. However, the extent and mechanism of this activation are unknown. Here
we show that about 100 heterochromatic TEs are activated in VCs, mostly by DEMETER-catalyzed
DNA demethylation. We further demonstrate that DEMETER access to some of these
TEs is permitted by the natural depletion of linker histone H1 in VCs. Ectopically
expressed H1 suppresses TEs in VCs by reducing DNA demethylation and via a methylation-independent
mechanism. We demonstrate that H1 is required for heterochromatin condensation
in plant cells and show that H1 overexpression creates heterochromatic foci in
the VC progenitor cell. Taken together, our results demonstrate that the natural
depletion of H1 during male gametogenesis facilitates DEMETER-directed DNA demethylation,
heterochromatin relaxation, and TE activation.
acknowledgement: We thank David Twell for the pDONR-P4-P1R-pLAT52 and pDONR-P2R-P3-mRFP
vectors, the John Innes Centre Bioimaging Facility (Elaine Barclay and Grant Calder)
for their assistance with microscopy, and the Norwich BioScience Institute Partnership
Computing infrastructure for Science Group for High Performance Computing resources.
This work was funded by a Biotechnology and Biological Sciences Research Council
(BBSRC) David Phillips Fellowship (BB/L025043/1; SH, JZ and XF), a European Research
Council Starting Grant ('SexMeth' 804981; XF) and a Grant to Exceptional Researchers
by the Gatsby Charitable Foundation (SH and XF).
article_number: '42530'
article_processing_charge: No
article_type: original
author:
- first_name: Shengbo
full_name: He, Shengbo
last_name: He
- first_name: Martin
full_name: Vickers, Martin
last_name: Vickers
- first_name: Jingyi
full_name: Zhang, Jingyi
last_name: Zhang
- first_name: Xiaoqi
full_name: Feng, Xiaoqi
id: e0164712-22ee-11ed-b12a-d80fcdf35958
last_name: Feng
orcid: 0000-0002-4008-1234
citation:
ama: He S, Vickers M, Zhang J, Feng X. Natural depletion of histone H1 in sex cells
causes DNA demethylation, heterochromatin decondensation and transposon activation.
eLife. 2019;8. doi:10.7554/elife.42530
apa: He, S., Vickers, M., Zhang, J., & Feng, X. (2019). Natural depletion of
histone H1 in sex cells causes DNA demethylation, heterochromatin decondensation
and transposon activation. ELife. eLife Sciences Publications. https://doi.org/10.7554/elife.42530
chicago: He, Shengbo, Martin Vickers, Jingyi Zhang, and Xiaoqi Feng. “Natural Depletion
of Histone H1 in Sex Cells Causes DNA Demethylation, Heterochromatin Decondensation
and Transposon Activation.” ELife. eLife Sciences Publications, 2019. https://doi.org/10.7554/elife.42530.
ieee: S. He, M. Vickers, J. Zhang, and X. Feng, “Natural depletion of histone H1
in sex cells causes DNA demethylation, heterochromatin decondensation and transposon
activation,” eLife, vol. 8. eLife Sciences Publications, 2019.
ista: He S, Vickers M, Zhang J, Feng X. 2019. Natural depletion of histone H1 in
sex cells causes DNA demethylation, heterochromatin decondensation and transposon
activation. eLife. 8, 42530.
mla: He, Shengbo, et al. “Natural Depletion of Histone H1 in Sex Cells Causes DNA
Demethylation, Heterochromatin Decondensation and Transposon Activation.” ELife,
vol. 8, 42530, eLife Sciences Publications, 2019, doi:10.7554/elife.42530.
short: S. He, M. Vickers, J. Zhang, X. Feng, ELife 8 (2019).
date_created: 2023-01-16T09:17:21Z
date_published: 2019-05-28T00:00:00Z
date_updated: 2025-01-14T14:31:41Z
day: '28'
ddc:
- '580'
department:
- _id: XiFe
doi: 10.7554/elife.42530
extern: '1'
external_id:
unknown:
- '31135340'
file:
- access_level: open_access
checksum: ea6b89c20d59e5eb3646916fe5d568ad
content_type: application/pdf
creator: alisjak
date_created: 2023-02-07T09:42:46Z
date_updated: 2023-02-07T09:42:46Z
file_id: '12525'
file_name: 2019_elife_He.pdf
file_size: 2493837
relation: main_file
success: 1
file_date_updated: 2023-02-07T09:42:46Z
has_accepted_license: '1'
intvolume: ' 8'
keyword:
- General Immunology and Microbiology
- General Biochemistry
- Genetics and Molecular Biology
- General Medicine
- General Neuroscience
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
publication: eLife
publication_identifier:
issn:
- 2050-084X
publication_status: published
publisher: eLife Sciences Publications
quality_controlled: '1'
scopus_import: '1'
status: public
title: Natural depletion of histone H1 in sex cells causes DNA demethylation, heterochromatin
decondensation and transposon activation
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2019'
...
---
_id: '12600'
abstract:
- lang: eng
text: The snow cover dynamics of High Mountain Asia are usually assessed at spatial
resolutions of 250 m or greater, but this scale is too coarse to clearly represent
the rugged topography common to the region. Higher-resolution measurement of snow-covered
area often results in biased sampling due to cloud cover and deep shadows. We
therefore develop a Normalized Difference Snow Index-based workflow to delineate
snow lines from Landsat Thematic Mapper/Enhanced Thematic Mapper+ imagery and
apply it to the upper Langtang Valley in Nepal, processing 194 scenes spanning
1999 to 2013. For each scene, we determine the spatial distribution of snow line
altitudes (SLAs) with respect to aspect and across six subcatchments. Our results
show that the mean SLA exhibits distinct seasonal behavior based on aspect and
subcatchment position. We find that SLA dynamics respond to spatial and seasonal
trade-offs in precipitation, temperature, and solar radiation, which act as primary
controls. We identify two SLA spatial gradients, which we attribute to the effect
of spatially variable precipitation. Our results also reveal that aspect-related
SLA differences vary seasonally and are influenced by solar radiation. In terms
of seasonal dominant controls, we demonstrate that the snow line is controlled
by snow precipitation in winter, melt in premonsoon, a combination of both in
postmonsoon, and temperature in monsoon, explaining to a large extent the spatial
and seasonal variability of the SLA in the upper Langtang Valley. We conclude
that while SLA and snow-covered area are complementary metrics, the SLA has a
strong potential for understanding local-scale snow cover dynamics and their controlling
mechanisms.
article_processing_charge: No
article_type: original
author:
- first_name: Marc
full_name: Girona‐Mata, Marc
last_name: Girona‐Mata
- first_name: Evan S.
full_name: Miles, Evan S.
last_name: Miles
- first_name: Silvan
full_name: Ragettli, Silvan
last_name: Ragettli
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
citation:
ama: Girona‐Mata M, Miles ES, Ragettli S, Pellicciotti F. High‐resolution snowline
delineation from Landsat imagery to infer snow cover controls in a Himalayan catchment.
Water Resources Research. 2019;55(8):6754-6772. doi:10.1029/2019wr024935
apa: Girona‐Mata, M., Miles, E. S., Ragettli, S., & Pellicciotti, F. (2019).
High‐resolution snowline delineation from Landsat imagery to infer snow cover
controls in a Himalayan catchment. Water Resources Research. American Geophysical
Union. https://doi.org/10.1029/2019wr024935
chicago: Girona‐Mata, Marc, Evan S. Miles, Silvan Ragettli, and Francesca Pellicciotti.
“High‐resolution Snowline Delineation from Landsat Imagery to Infer Snow Cover
Controls in a Himalayan Catchment.” Water Resources Research. American
Geophysical Union, 2019. https://doi.org/10.1029/2019wr024935.
ieee: M. Girona‐Mata, E. S. Miles, S. Ragettli, and F. Pellicciotti, “High‐resolution
snowline delineation from Landsat imagery to infer snow cover controls in a Himalayan
catchment,” Water Resources Research, vol. 55, no. 8. American Geophysical
Union, pp. 6754–6772, 2019.
ista: Girona‐Mata M, Miles ES, Ragettli S, Pellicciotti F. 2019. High‐resolution
snowline delineation from Landsat imagery to infer snow cover controls in a Himalayan
catchment. Water Resources Research. 55(8), 6754–6772.
mla: Girona‐Mata, Marc, et al. “High‐resolution Snowline Delineation from Landsat
Imagery to Infer Snow Cover Controls in a Himalayan Catchment.” Water Resources
Research, vol. 55, no. 8, American Geophysical Union, 2019, pp. 6754–72, doi:10.1029/2019wr024935.
short: M. Girona‐Mata, E.S. Miles, S. Ragettli, F. Pellicciotti, Water Resources
Research 55 (2019) 6754–6772.
date_created: 2023-02-20T08:12:59Z
date_published: 2019-08-01T00:00:00Z
date_updated: 2023-02-28T12:14:18Z
day: '01'
doi: 10.1029/2019wr024935
extern: '1'
intvolume: ' 55'
issue: '8'
keyword:
- Water Science and Technology
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1029/2019WR024935
month: '08'
oa: 1
oa_version: Published Version
page: 6754-6772
publication: Water Resources Research
publication_identifier:
eissn:
- 1944-7973
issn:
- 0043-1397
publication_status: published
publisher: American Geophysical Union
quality_controlled: '1'
scopus_import: '1'
status: public
title: High‐resolution snowline delineation from Landsat imagery to infer snow cover
controls in a Himalayan catchment
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 55
year: '2019'
...
---
_id: '12601'
abstract:
- lang: eng
text: Ice cliffs and ponds on debris-covered glaciers have received increased attention
due to their role in amplifying local melt. However, very few studies have looked
at these features on the catchment scale to determine their patterns and changes
in space and time. We have compiled a detailed inventory of cliffs and ponds in
the Langtang catchment, central Himalaya, from six high-resolution satellite orthoimages
and DEMs between 2006 and 2015, and a historic orthophoto from 1974. Cliffs cover
between 1.4% (± 0.4%) in the dry and 3.4% (± 0.9%) in the wet seasons and ponds
between 0.6% (± 0.1%) and 1.6% (± 0.3%) of the total debris-covered tongues. We
find large variations between seasons, as cliffs and ponds tend to grow in the
wetter monsoon period, but there is no obvious trend in total area over the study
period. The inventory further shows that cliffs are predominately north-facing
irrespective of the glacier flow direction. Both cliffs and ponds appear in higher
densities several hundred metres from the terminus in areas where tributaries
reach the main glacier tongue. On the largest glacier in the catchment ~10% of
all cliffs and ponds persisted over nearly a decade.
article_processing_charge: No
article_type: original
author:
- first_name: JAKOB F.
full_name: STEINER, JAKOB F.
last_name: STEINER
- first_name: PASCAL
full_name: BURI, PASCAL
last_name: BURI
- first_name: EVAN S.
full_name: MILES, EVAN S.
last_name: MILES
- first_name: SILVAN
full_name: RAGETTLI, SILVAN
last_name: RAGETTLI
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
citation:
ama: 'STEINER JF, BURI P, MILES ES, RAGETTLI S, Pellicciotti F. Supraglacial ice
cliffs and ponds on debris-covered glaciers: Spatio-temporal distribution and
characteristics. Journal of Glaciology. 2019;65(252):617-632. doi:10.1017/jog.2019.40'
apa: 'STEINER, J. F., BURI, P., MILES, E. S., RAGETTLI, S., & Pellicciotti,
F. (2019). Supraglacial ice cliffs and ponds on debris-covered glaciers: Spatio-temporal
distribution and characteristics. Journal of Glaciology. Cambridge University
Press. https://doi.org/10.1017/jog.2019.40'
chicago: 'STEINER, JAKOB F., PASCAL BURI, EVAN S. MILES, SILVAN RAGETTLI, and Francesca
Pellicciotti. “Supraglacial Ice Cliffs and Ponds on Debris-Covered Glaciers: Spatio-Temporal
Distribution and Characteristics.” Journal of Glaciology. Cambridge University
Press, 2019. https://doi.org/10.1017/jog.2019.40.'
ieee: 'J. F. STEINER, P. BURI, E. S. MILES, S. RAGETTLI, and F. Pellicciotti, “Supraglacial
ice cliffs and ponds on debris-covered glaciers: Spatio-temporal distribution
and characteristics,” Journal of Glaciology, vol. 65, no. 252. Cambridge
University Press, pp. 617–632, 2019.'
ista: 'STEINER JF, BURI P, MILES ES, RAGETTLI S, Pellicciotti F. 2019. Supraglacial
ice cliffs and ponds on debris-covered glaciers: Spatio-temporal distribution
and characteristics. Journal of Glaciology. 65(252), 617–632.'
mla: 'STEINER, JAKOB F., et al. “Supraglacial Ice Cliffs and Ponds on Debris-Covered
Glaciers: Spatio-Temporal Distribution and Characteristics.” Journal of Glaciology,
vol. 65, no. 252, Cambridge University Press, 2019, pp. 617–32, doi:10.1017/jog.2019.40.'
short: J.F. STEINER, P. BURI, E.S. MILES, S. RAGETTLI, F. Pellicciotti, Journal
of Glaciology 65 (2019) 617–632.
date_created: 2023-02-20T08:13:03Z
date_published: 2019-08-01T00:00:00Z
date_updated: 2023-02-28T12:11:07Z
day: '01'
doi: 10.1017/jog.2019.40
extern: '1'
intvolume: ' 65'
issue: '252'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1017/jog.2019.40
month: '08'
oa: 1
oa_version: Published Version
page: 617-632
publication: Journal of Glaciology
publication_identifier:
eissn:
- 1727-5652
issn:
- 0022-1430
publication_status: published
publisher: Cambridge University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Supraglacial ice cliffs and ponds on debris-covered glaciers: Spatio-temporal
distribution and characteristics'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 65
year: '2019'
...
---
_id: '12602'
abstract:
- lang: eng
text: 'This study aims at developing and applying a spatially-distributed coupled
glacier mass balance and ice-flow model to attribute the response of glaciers
to natural and anthropogenic climate change. We focus on two glaciers with contrasting
surface characteristics: a debris-covered glacier (Langtang Glacier in Nepal)
and a clean-ice glacier (Hintereisferner in Austria). The model is applied from
the end of the Little Ice Age (1850) to the present-day (2016) and is forced with
four bias-corrected General Circulation Models (GCMs) from the historical experiment
of the CMIP5 archive. The selected GCMs represent region-specific warm-dry, warm-wet,
cold-dry, and cold-wet climate conditions. To isolate the effects of anthropogenic
climate change on glacier mass balance and flow runs from these GCMs with and
without further anthropogenic forcing after 1970 until 2016 are selected. The
outcomes indicate that both glaciers experience the largest reduction in area
and volume under warm climate conditions, whereas area and volume reductions are
smaller under cold climate conditions. Simultaneously with changes in glacier
area and volume, surface velocities generally decrease over time. Without further
anthropogenic forcing the results reveal a 3% (9%) smaller decline in glacier
area (volume) for the debris-covered glacier and a 18% (39%) smaller decline in
glacier area (volume) for the clean-ice glacier. The difference in the magnitude
between the two glaciers can mainly be attributed to differences in the response
time of the glaciers, where the clean-ice glacier shows a much faster response
to climate change. We conclude that the response of the two glaciers can mainly
be attributed to anthropogenic climate change and that the impact is larger on
the clean-ice glacier. The outcomes show that the model performs well under different
climate conditions and that the developed approach can be used for regional-scale
glacio-hydrological modeling.'
article_number: '143'
article_processing_charge: No
article_type: original
author:
- first_name: René R.
full_name: Wijngaard, René R.
last_name: Wijngaard
- first_name: Jakob F.
full_name: Steiner, Jakob F.
last_name: Steiner
- first_name: Philip D. A.
full_name: Kraaijenbrink, Philip D. A.
last_name: Kraaijenbrink
- first_name: Christoph
full_name: Klug, Christoph
last_name: Klug
- first_name: Surendra
full_name: Adhikari, Surendra
last_name: Adhikari
- first_name: Argha
full_name: Banerjee, Argha
last_name: Banerjee
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
- first_name: Ludovicus P. H.
full_name: van Beek, Ludovicus P. H.
last_name: van Beek
- first_name: Marc F. P.
full_name: Bierkens, Marc F. P.
last_name: Bierkens
- first_name: Arthur F.
full_name: Lutz, Arthur F.
last_name: Lutz
- first_name: Walter W.
full_name: Immerzeel, Walter W.
last_name: Immerzeel
citation:
ama: Wijngaard RR, Steiner JF, Kraaijenbrink PDA, et al. Modeling the response of
the Langtang Glacier and the Hintereisferner to a changing climate since the Little
Ice Age. Frontiers in Earth Science. 2019;7. doi:10.3389/feart.2019.00143
apa: Wijngaard, R. R., Steiner, J. F., Kraaijenbrink, P. D. A., Klug, C., Adhikari,
S., Banerjee, A., … Immerzeel, W. W. (2019). Modeling the response of the Langtang
Glacier and the Hintereisferner to a changing climate since the Little Ice Age.
Frontiers in Earth Science. Frontiers Media. https://doi.org/10.3389/feart.2019.00143
chicago: Wijngaard, René R., Jakob F. Steiner, Philip D. A. Kraaijenbrink, Christoph
Klug, Surendra Adhikari, Argha Banerjee, Francesca Pellicciotti, et al. “Modeling
the Response of the Langtang Glacier and the Hintereisferner to a Changing Climate
since the Little Ice Age.” Frontiers in Earth Science. Frontiers Media,
2019. https://doi.org/10.3389/feart.2019.00143.
ieee: R. R. Wijngaard et al., “Modeling the response of the Langtang Glacier
and the Hintereisferner to a changing climate since the Little Ice Age,” Frontiers
in Earth Science, vol. 7. Frontiers Media, 2019.
ista: Wijngaard RR, Steiner JF, Kraaijenbrink PDA, Klug C, Adhikari S, Banerjee
A, Pellicciotti F, van Beek LPH, Bierkens MFP, Lutz AF, Immerzeel WW. 2019. Modeling
the response of the Langtang Glacier and the Hintereisferner to a changing climate
since the Little Ice Age. Frontiers in Earth Science. 7, 143.
mla: Wijngaard, René R., et al. “Modeling the Response of the Langtang Glacier and
the Hintereisferner to a Changing Climate since the Little Ice Age.” Frontiers
in Earth Science, vol. 7, 143, Frontiers Media, 2019, doi:10.3389/feart.2019.00143.
short: R.R. Wijngaard, J.F. Steiner, P.D.A. Kraaijenbrink, C. Klug, S. Adhikari,
A. Banerjee, F. Pellicciotti, L.P.H. van Beek, M.F.P. Bierkens, A.F. Lutz, W.W.
Immerzeel, Frontiers in Earth Science 7 (2019).
date_created: 2023-02-20T08:13:08Z
date_published: 2019-06-04T00:00:00Z
date_updated: 2023-02-28T12:04:48Z
day: '04'
doi: 10.3389/feart.2019.00143
extern: '1'
intvolume: ' 7'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.3389/feart.2019.00143
month: '06'
oa: 1
oa_version: Published Version
publication: Frontiers in Earth Science
publication_identifier:
issn:
- 2296-6463
publication_status: published
publisher: Frontiers Media
quality_controlled: '1'
scopus_import: '1'
status: public
title: Modeling the response of the Langtang Glacier and the Hintereisferner to a
changing climate since the Little Ice Age
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2019'
...
---
_id: '12901'
article_processing_charge: No
author:
- first_name: Alois
full_name: Schlögl, Alois
id: 45BF87EE-F248-11E8-B48F-1D18A9856A87
last_name: Schlögl
orcid: 0000-0002-5621-8100
- first_name: Janos
full_name: Kiss, Janos
id: 3D3A06F8-F248-11E8-B48F-1D18A9856A87
last_name: Kiss
- first_name: Stefano
full_name: Elefante, Stefano
id: 490F40CE-F248-11E8-B48F-1D18A9856A87
last_name: Elefante
citation:
ama: 'Schlögl A, Kiss J, Elefante S. Is Debian suitable for running an HPC Cluster?
In: AHPC19 - Austrian HPC Meeting 2019 . Institut für Mathematik und wissenschaftliches
Rechnen der Universität Graz; 2019:25.'
apa: 'Schlögl, A., Kiss, J., & Elefante, S. (2019). Is Debian suitable for running
an HPC Cluster? In AHPC19 - Austrian HPC Meeting 2019 (p. 25). Grundlsee,
Austria: Institut für Mathematik und wissenschaftliches Rechnen der Universität
Graz.'
chicago: Schlögl, Alois, Janos Kiss, and Stefano Elefante. “Is Debian Suitable for
Running an HPC Cluster?” In AHPC19 - Austrian HPC Meeting 2019 , 25. Institut
für Mathematik und wissenschaftliches Rechnen der Universität Graz, 2019.
ieee: A. Schlögl, J. Kiss, and S. Elefante, “Is Debian suitable for running an HPC
Cluster?,” in AHPC19 - Austrian HPC Meeting 2019 , Grundlsee, Austria,
2019, p. 25.
ista: 'Schlögl A, Kiss J, Elefante S. 2019. Is Debian suitable for running an HPC
Cluster? AHPC19 - Austrian HPC Meeting 2019 . AHPC: Austrian HPC Meeting, 25.'
mla: Schlögl, Alois, et al. “Is Debian Suitable for Running an HPC Cluster?” AHPC19
- Austrian HPC Meeting 2019 , Institut für Mathematik und wissenschaftliches
Rechnen der Universität Graz, 2019, p. 25.
short: A. Schlögl, J. Kiss, S. Elefante, in:, AHPC19 - Austrian HPC Meeting 2019
, Institut für Mathematik und wissenschaftliches Rechnen der Universität Graz,
2019, p. 25.
conference:
end_date: 2019-02-27
location: Grundlsee, Austria
name: 'AHPC: Austrian HPC Meeting'
start_date: 2019-02-25
corr_author: '1'
date_created: 2023-05-05T12:48:48Z
date_published: 2019-02-27T00:00:00Z
date_updated: 2024-10-09T21:05:24Z
day: '27'
ddc:
- '000'
department:
- _id: ScienComp
file:
- access_level: open_access
checksum: acc8272027faaf30709c51ac5c58ffa4
content_type: application/pdf
creator: dernst
date_created: 2023-05-16T07:27:09Z
date_updated: 2023-05-16T07:27:09Z
file_id: '12970'
file_name: 2019_AHPC_Schloegl.pdf
file_size: 1097603
relation: main_file
success: 1
file_date_updated: 2023-05-16T07:27:09Z
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://vsc.ac.at/fileadmin/user_upload/vsc/conferences/ahpc19/BOOKLET_AHPC19.pdf
month: '02'
oa: 1
oa_version: Published Version
page: '25'
publication: 'AHPC19 - Austrian HPC Meeting 2019 '
publication_status: published
publisher: Institut für Mathematik und wissenschaftliches Rechnen der Universität
Graz
status: public
title: Is Debian suitable for running an HPC Cluster?
type: conference_abstract
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2019'
...
---
_id: '13067'
abstract:
- lang: eng
text: Genetic incompatibilities contribute to reproductive isolation between many
diverging populations, but it is still unclear to what extent they play a role
if divergence happens with gene flow. In contact zones between the "Crab" and
"Wave" ecotypes of the snail Littorina saxatilis divergent selection forms strong
barriers to gene flow, while the role of postzygotic barriers due to selection
against hybrids remains unclear. High embryo abortion rates in this species could
indicate the presence of such barriers. Postzygotic barriers might include genetic
incompatibilities (e.g. Dobzhansky-Muller incompatibilities) but also maladaptation,
both expected to be most pronounced in contact zones. In addition, embryo abortion
might reflect physiological stress on females and embryos independent of any genetic
stress. We examined all embryos of >500 females sampled outside and inside
contact zones of three populations in Sweden. Females' clutch size ranged from
0 to 1011 embryos (mean 130±123) and abortion rates varied between 0 and100% (mean
12%). We described female genotypes by using a hybrid index based on hundreds
of SNPs differentiated between ecotypes with which we characterised female genotypes.
We also calculated female SNP heterozygosity and inversion karyotype. Clutch size
did not vary with female hybrid index and abortion rates were only weakly related
to hybrid index in two sites but not at all in a third site. No additional variation
in abortion rate was explained by female SNP heterozygosity, but increased female
inversion heterozygosity added slightly to increased abortion. Our results show
only weak and probably biologically insignificant postzygotic barriers contributing
to ecotype divergence and the high and variable abortion rates were marginally,
if at all, explained by hybrid index of females.
article_processing_charge: No
author:
- first_name: Kerstin
full_name: Johannesson, Kerstin
last_name: Johannesson
- first_name: Zuzanna
full_name: Zagrodzka, Zuzanna
last_name: Zagrodzka
- first_name: Rui
full_name: Faria, Rui
last_name: Faria
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
- first_name: Roger
full_name: Butlin, Roger
last_name: Butlin
citation:
ama: 'Johannesson K, Zagrodzka Z, Faria R, Westram AM, Butlin R. Data from: Is embryo
abortion a postzygotic barrier to gene flow between Littorina ecotypes? 2019.
doi:10.5061/DRYAD.TB2RBNZWK'
apa: 'Johannesson, K., Zagrodzka, Z., Faria, R., Westram, A. M., & Butlin, R.
(2019). Data from: Is embryo abortion a postzygotic barrier to gene flow between
Littorina ecotypes? Dryad. https://doi.org/10.5061/DRYAD.TB2RBNZWK'
chicago: 'Johannesson, Kerstin, Zuzanna Zagrodzka, Rui Faria, Anja M Westram, and
Roger Butlin. “Data from: Is Embryo Abortion a Postzygotic Barrier to Gene Flow
between Littorina Ecotypes?” Dryad, 2019. https://doi.org/10.5061/DRYAD.TB2RBNZWK.'
ieee: 'K. Johannesson, Z. Zagrodzka, R. Faria, A. M. Westram, and R. Butlin, “Data
from: Is embryo abortion a postzygotic barrier to gene flow between Littorina
ecotypes?” Dryad, 2019.'
ista: 'Johannesson K, Zagrodzka Z, Faria R, Westram AM, Butlin R. 2019. Data from:
Is embryo abortion a postzygotic barrier to gene flow between Littorina ecotypes?,
Dryad, 10.5061/DRYAD.TB2RBNZWK.'
mla: 'Johannesson, Kerstin, et al. Data from: Is Embryo Abortion a Postzygotic
Barrier to Gene Flow between Littorina Ecotypes? Dryad, 2019, doi:10.5061/DRYAD.TB2RBNZWK.'
short: K. Johannesson, Z. Zagrodzka, R. Faria, A.M. Westram, R. Butlin, (2019).
date_created: 2023-05-23T16:36:27Z
date_published: 2019-12-02T00:00:00Z
date_updated: 2025-07-10T11:54:22Z
day: '02'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.5061/DRYAD.TB2RBNZWK
license: https://creativecommons.org/publicdomain/zero/1.0/
main_file_link:
- open_access: '1'
url: https://doi.org/10.5061/dryad.tb2rbnzwk
month: '12'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
record:
- id: '7205'
relation: used_in_publication
status: public
status: public
title: 'Data from: Is embryo abortion a postzygotic barrier to gene flow between Littorina
ecotypes?'
tmp:
image: /images/cc_0.png
legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
name: Creative Commons Public Domain Dedication (CC0 1.0)
short: CC0 (1.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2019'
...
---
_id: '13079'
abstract:
- lang: eng
text: The inner nuclear membrane (INM) is a subdomain of the endoplasmic reticulum
(ER) that is gated by the nuclear pore complex. It is unknown whether proteins
of the INM and ER are degraded through shared or distinct pathways in mammalian
cells. We applied dynamic proteomics to profile protein half-lives and report
that INM and ER residents turn over at similar rates, indicating that the INM’s
unique topology is not a barrier to turnover. Using a microscopy approach, we
observed that the proteasome can degrade INM proteins in situ. However, we also
uncovered evidence for selective, vesicular transport-mediated turnover of a single
INM protein, emerin, that is potentiated by ER stress. Emerin is rapidly cleared
from the INM by a mechanism that requires emerin’s LEM domain to mediate vesicular
trafficking to lysosomes. This work demonstrates that the INM can be dynamically
remodeled in response to environmental inputs.
article_processing_charge: No
author:
- first_name: Abigail
full_name: Buchwalter, Abigail
last_name: Buchwalter
- first_name: Roberta
full_name: Schulte, Roberta
last_name: Schulte
- first_name: Hsiao
full_name: Tsai, Hsiao
last_name: Tsai
- first_name: Juliana
full_name: Capitanio, Juliana
last_name: Capitanio
- first_name: Martin W
full_name: HETZER, Martin W
id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
last_name: HETZER
orcid: 0000-0002-2111-992X
citation:
ama: 'Buchwalter A, Schulte R, Tsai H, Capitanio J, Hetzer M. Data from: Selective
clearance of the inner nuclear membrane protein emerin by vesicular transport
during ER stress. 2019. doi:10.5061/DRYAD.N0R525H'
apa: 'Buchwalter, A., Schulte, R., Tsai, H., Capitanio, J., & Hetzer, M. (2019).
Data from: Selective clearance of the inner nuclear membrane protein emerin by
vesicular transport during ER stress. Dryad. https://doi.org/10.5061/DRYAD.N0R525H'
chicago: 'Buchwalter, Abigail, Roberta Schulte, Hsiao Tsai, Juliana Capitanio, and
Martin Hetzer. “Data from: Selective Clearance of the Inner Nuclear Membrane Protein
Emerin by Vesicular Transport during ER Stress.” Dryad, 2019. https://doi.org/10.5061/DRYAD.N0R525H.'
ieee: 'A. Buchwalter, R. Schulte, H. Tsai, J. Capitanio, and M. Hetzer, “Data from:
Selective clearance of the inner nuclear membrane protein emerin by vesicular
transport during ER stress.” Dryad, 2019.'
ista: 'Buchwalter A, Schulte R, Tsai H, Capitanio J, Hetzer M. 2019. Data from:
Selective clearance of the inner nuclear membrane protein emerin by vesicular
transport during ER stress, Dryad, 10.5061/DRYAD.N0R525H.'
mla: 'Buchwalter, Abigail, et al. Data from: Selective Clearance of the Inner
Nuclear Membrane Protein Emerin by Vesicular Transport during ER Stress. Dryad,
2019, doi:10.5061/DRYAD.N0R525H.'
short: A. Buchwalter, R. Schulte, H. Tsai, J. Capitanio, M. Hetzer, (2019).
date_created: 2023-05-23T17:09:30Z
date_published: 2019-10-28T00:00:00Z
date_updated: 2024-10-14T12:08:37Z
day: '28'
ddc:
- '570'
doi: 10.5061/DRYAD.N0R525H
extern: '1'
main_file_link:
- open_access: '1'
url: https://doi.org/10.5061/dryad.n0r525h
month: '10'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
record:
- id: '11060'
relation: used_in_publication
status: public
status: public
title: 'Data from: Selective clearance of the inner nuclear membrane protein emerin
by vesicular transport during ER stress'
tmp:
image: /images/cc_0.png
legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
name: Creative Commons Public Domain Dedication (CC0 1.0)
short: CC0 (1.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2019'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '21095'
abstract:
- lang: eng
text: 'Inspired by DNA mimic proteins, we have introduced aromatic foldamers bearing
phosphonate groups as synthetic mimics of the charge surface of B-DNA and competitive
inhibitors of some therapeutically relevant DNA-binding enzymes: the human DNA
Topoisomerase 1 (Top1) and the human HIV-1 integrase (HIV-1 IN). We now report
on variants of these anionic foldamers bearing carboxylates instead of phosphonates.
Several new monomers have been synthesized with protecting groups suitable for
solid phase synthesis (SPS). Six hexadecaamides have been prepared using SPS.
Proof of their resemblance to B-DNA was brought by the first crystal structure
of one of these DNA-mimic foldamers in its polyanionic form. While some of the
foldamers were found to be as active as, or even more active than, the original
phosphonate oligomers, others had no activity at all or could even stimulate enzyme
activity in vitro. Some foldamers were found to have differential inhibitory effects
on the two enzymes. These results demonstrate a strong dependence of inhibitory
activity on foldamer structure and charge distribution. They open broad avenues
for the development of new classes of derivatives that could inhibit the interaction
of specific proteins with their DNA target thereby influencing the cellular pathways
in which they are involved.'
article_processing_charge: No
article_type: original
author:
- first_name: Valentina
full_name: Corvaglia, Valentina
last_name: Corvaglia
- first_name: Daniel
full_name: Carbajo, Daniel
last_name: Carbajo
- first_name: Panchami
full_name: Prabhakaran, Panchami
last_name: Prabhakaran
- first_name: Krzysztof
full_name: Ziach, Krzysztof
last_name: Ziach
- first_name: Pradeep K
full_name: Mandal, Pradeep K
id: 6a3def15-d4b4-11ef-9fa9-a24c1f545ec3
last_name: Mandal
orcid: 0000-0001-5996-956X
- first_name: Victor Dos
full_name: Santos, Victor Dos
last_name: Santos
- first_name: Carole
full_name: Legeay, Carole
last_name: Legeay
- first_name: Rachel
full_name: Vogel, Rachel
last_name: Vogel
- first_name: Vincent
full_name: Parissi, Vincent
last_name: Parissi
- first_name: Philippe
full_name: Pourquier, Philippe
last_name: Pourquier
- first_name: Ivan
full_name: Huc, Ivan
last_name: Huc
citation:
ama: 'Corvaglia V, Carbajo D, Prabhakaran P, et al. Carboxylate-functionalized foldamer
inhibitors of HIV-1 integrase and Topoisomerase 1: Artificial analogues of DNA
mimic proteins. Nucleic Acids Research. 2019;47(11):5511-5521. doi:10.1093/nar/gkz352'
apa: 'Corvaglia, V., Carbajo, D., Prabhakaran, P., Ziach, K., Mandal, P. K., Santos,
V. D., … Huc, I. (2019). Carboxylate-functionalized foldamer inhibitors of HIV-1
integrase and Topoisomerase 1: Artificial analogues of DNA mimic proteins. Nucleic
Acids Research. Oxford University Press. https://doi.org/10.1093/nar/gkz352'
chicago: 'Corvaglia, Valentina, Daniel Carbajo, Panchami Prabhakaran, Krzysztof
Ziach, Pradeep K Mandal, Victor Dos Santos, Carole Legeay, et al. “Carboxylate-Functionalized
Foldamer Inhibitors of HIV-1 Integrase and Topoisomerase 1: Artificial Analogues
of DNA Mimic Proteins.” Nucleic Acids Research. Oxford University Press,
2019. https://doi.org/10.1093/nar/gkz352.'
ieee: 'V. Corvaglia et al., “Carboxylate-functionalized foldamer inhibitors
of HIV-1 integrase and Topoisomerase 1: Artificial analogues of DNA mimic proteins,”
Nucleic Acids Research, vol. 47, no. 11. Oxford University Press, pp. 5511–5521,
2019.'
ista: 'Corvaglia V, Carbajo D, Prabhakaran P, Ziach K, Mandal PK, Santos VD, Legeay
C, Vogel R, Parissi V, Pourquier P, Huc I. 2019. Carboxylate-functionalized foldamer
inhibitors of HIV-1 integrase and Topoisomerase 1: Artificial analogues of DNA
mimic proteins. Nucleic Acids Research. 47(11), 5511–5521.'
mla: 'Corvaglia, Valentina, et al. “Carboxylate-Functionalized Foldamer Inhibitors
of HIV-1 Integrase and Topoisomerase 1: Artificial Analogues of DNA Mimic Proteins.”
Nucleic Acids Research, vol. 47, no. 11, Oxford University Press, 2019,
pp. 5511–21, doi:10.1093/nar/gkz352.'
short: V. Corvaglia, D. Carbajo, P. Prabhakaran, K. Ziach, P.K. Mandal, V.D. Santos,
C. Legeay, R. Vogel, V. Parissi, P. Pourquier, I. Huc, Nucleic Acids Research
47 (2019) 5511–5521.
date_created: 2026-01-29T21:17:15Z
date_published: 2019-06-20T00:00:00Z
date_updated: 2026-02-23T09:56:28Z
day: '20'
doi: 10.1093/nar/gkz352
extern: '1'
has_accepted_license: '1'
intvolume: ' 47'
issue: '11'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1093/nar/gkz352
month: '06'
oa: 1
oa_version: Published Version
page: 5511-5521
publication: Nucleic Acids Research
publication_identifier:
eissn:
- 1362-4962
issn:
- 0305-1048
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
status: public
title: 'Carboxylate-functionalized foldamer inhibitors of HIV-1 integrase and Topoisomerase
1: Artificial analogues of DNA mimic proteins'
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 47
year: '2019'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '21538'
abstract:
- lang: eng
text: Extracting light from silicon is a longstanding challenge in modern engineering
and physics. While silicon has underpinned the past 70 years of electronics advancement,
a facile tunable and efficient silicon-based light source remains elusive. Here,
we experimentally demonstrate the generation of tunable radiation from a one-dimensional,
all-silicon nanograting. Light is generated by the spontaneous emission from the
interaction of these nanogratings with low-energy free electrons (2–20 keV) and
is recorded in the wavelength range of 800–1600 nm, which includes the silicon
transparency window. Tunable free-electron-based light generation from nanoscale
silicon gratings with efficiencies approaching those from metallic gratings is
demonstrated. We theoretically investigate the feasibility of a scalable, compact,
all-silicon tunable light source comprised of a silicon Field Emitter Array integrated
with a silicon nanograting that emits at telecommunication wavelengths. Our results
reveal the prospects of a CMOS-compatible electrically-pumped silicon light source
for possible applications in the mid-infrared and telecommunication wavelengths.
article_number: '3176'
article_processing_charge: No
article_type: original
author:
- first_name: Charles
full_name: Roques-Carmes, Charles
id: e2e68fc9-6505-11ef-a541-eb4e72cc3e82
last_name: Roques-Carmes
- first_name: Steven E.
full_name: Kooi, Steven E.
last_name: Kooi
- first_name: Yi
full_name: Yang, Yi
last_name: Yang
- first_name: Aviram
full_name: Massuda, Aviram
last_name: Massuda
- first_name: Phillip D.
full_name: Keathley, Phillip D.
last_name: Keathley
- first_name: Aun
full_name: Zaidi, Aun
last_name: Zaidi
- first_name: Yujia
full_name: Yang, Yujia
last_name: Yang
- first_name: John D.
full_name: Joannopoulos, John D.
last_name: Joannopoulos
- first_name: Karl K.
full_name: Berggren, Karl K.
last_name: Berggren
- first_name: Ido
full_name: Kaminer, Ido
last_name: Kaminer
- first_name: Marin
full_name: Soljačić, Marin
last_name: Soljačić
citation:
ama: Roques-Carmes C, Kooi SE, Yang Y, et al. Towards integrated tunable all-silicon
free-electron light sources. Nature Communications. 2019;10. doi:10.1038/s41467-019-11070-7
apa: Roques-Carmes, C., Kooi, S. E., Yang, Y., Massuda, A., Keathley, P. D., Zaidi,
A., … Soljačić, M. (2019). Towards integrated tunable all-silicon free-electron
light sources. Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-019-11070-7
chicago: Roques-Carmes, Charles, Steven E. Kooi, Yi Yang, Aviram Massuda, Phillip
D. Keathley, Aun Zaidi, Yujia Yang, et al. “Towards Integrated Tunable All-Silicon
Free-Electron Light Sources.” Nature Communications. Springer Nature, 2019.
https://doi.org/10.1038/s41467-019-11070-7.
ieee: C. Roques-Carmes et al., “Towards integrated tunable all-silicon free-electron
light sources,” Nature Communications, vol. 10. Springer Nature, 2019.
ista: Roques-Carmes C, Kooi SE, Yang Y, Massuda A, Keathley PD, Zaidi A, Yang Y,
Joannopoulos JD, Berggren KK, Kaminer I, Soljačić M. 2019. Towards integrated
tunable all-silicon free-electron light sources. Nature Communications. 10, 3176.
mla: Roques-Carmes, Charles, et al. “Towards Integrated Tunable All-Silicon Free-Electron
Light Sources.” Nature Communications, vol. 10, 3176, Springer Nature,
2019, doi:10.1038/s41467-019-11070-7.
short: C. Roques-Carmes, S.E. Kooi, Y. Yang, A. Massuda, P.D. Keathley, A. Zaidi,
Y. Yang, J.D. Joannopoulos, K.K. Berggren, I. Kaminer, M. Soljačić, Nature Communications
10 (2019).
date_created: 2026-03-30T12:22:47Z
date_published: 2019-07-18T00:00:00Z
date_updated: 2026-04-15T06:58:28Z
day: '18'
ddc:
- '530'
doi: 10.1038/s41467-019-11070-7
extern: '1'
intvolume: ' 10'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1038/s41467-019-11070-7
month: '07'
oa: 1
oa_version: Published Version
publication: Nature Communications
publication_identifier:
eissn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Towards integrated tunable all-silicon free-electron light sources
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10
year: '2019'
...
---
OA_type: closed access
_id: '21557'
abstract:
- lang: eng
text: "A new optical processor for solving hard optimization problems breaks previous
size records and is based on a highly scalable technology.\r\n"
article_number: '61'
article_processing_charge: No
article_type: comment
author:
- first_name: Charles
full_name: Roques-Carmes, Charles
id: e2e68fc9-6505-11ef-a541-eb4e72cc3e82
last_name: Roques-Carmes
- first_name: Marin
full_name: Soljačić, Marin
last_name: Soljačić
citation:
ama: Roques-Carmes C, Soljačić M. Photonic ising machines go big. Physics.
2019;12. doi:10.1103/physics.12.61
apa: Roques-Carmes, C., & Soljačić, M. (2019). Photonic ising machines go big.
Physics. American Physical Society. https://doi.org/10.1103/physics.12.61
chicago: Roques-Carmes, Charles, and Marin Soljačić. “Photonic Ising Machines Go
Big.” Physics. American Physical Society, 2019. https://doi.org/10.1103/physics.12.61.
ieee: C. Roques-Carmes and M. Soljačić, “Photonic ising machines go big,” Physics,
vol. 12. American Physical Society, 2019.
ista: Roques-Carmes C, Soljačić M. 2019. Photonic ising machines go big. Physics.
12, 61.
mla: Roques-Carmes, Charles, and Marin Soljačić. “Photonic Ising Machines Go Big.”
Physics, vol. 12, 61, American Physical Society, 2019, doi:10.1103/physics.12.61.
short: C. Roques-Carmes, M. Soljačić, Physics 12 (2019).
date_created: 2026-03-30T12:22:47Z
date_published: 2019-05-31T00:00:00Z
date_updated: 2026-04-15T07:05:01Z
day: '31'
ddc:
- '530'
doi: 10.1103/physics.12.61
extern: '1'
intvolume: ' 12'
language:
- iso: eng
month: '05'
oa_version: None
publication: Physics
publication_identifier:
issn:
- 1943-2879
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Photonic ising machines go big
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2019'
...
---
OA_type: closed access
_id: '21568'
abstract:
- lang: eng
text: 'Optical approaches to AI acceleration have gained intense interest recently
due to the potentially breakthrough advantages of photonics: high bandwidth, low
power consumption, and efficient data movement. We overview leading photonic AI
platforms based on beamsplitter mesh networks, weight banks, and photoelectric
multiplication. While the theoretical performance can be orders of magnitude beyond
current state of the art, practical issues of chip area, input / output, and crosstalk
paint a more nuanced near-term picture of photonic AI acceleration. Both fundamental
and near-term limitations to energy efficiency are addressed, and bandwidth limitations
due to temporal crosstalk are analyzed.'
article_processing_charge: No
author:
- first_name: R.
full_name: Hamerly, R.
last_name: Hamerly
- first_name: A.
full_name: Sludds, A.
last_name: Sludds
- first_name: L.
full_name: Bernstein, L.
last_name: Bernstein
- first_name: M.
full_name: Prabhu, M.
last_name: Prabhu
- first_name: Charles
full_name: Roques-Carmes, Charles
id: e2e68fc9-6505-11ef-a541-eb4e72cc3e82
last_name: Roques-Carmes
- first_name: J.
full_name: Carolan, J.
last_name: Carolan
- first_name: Y.
full_name: Yamamoto, Y.
last_name: Yamamoto
- first_name: M.
full_name: Soljacic, M.
last_name: Soljacic
- first_name: D.
full_name: Englund, D.
last_name: Englund
citation:
ama: 'Hamerly R, Sludds A, Bernstein L, et al. Towards large-scale photonic neural-network
accelerators. In: 2019 IEEE International Electron Devices Meeting. IEEE;
2019. doi:10.1109/iedm19573.2019.8993624'
apa: 'Hamerly, R., Sludds, A., Bernstein, L., Prabhu, M., Roques-Carmes, C., Carolan,
J., … Englund, D. (2019). Towards large-scale photonic neural-network accelerators.
In 2019 IEEE International Electron Devices Meeting. San Francisco, CA,
United States: IEEE. https://doi.org/10.1109/iedm19573.2019.8993624'
chicago: Hamerly, R., A. Sludds, L. Bernstein, M. Prabhu, Charles Roques-Carmes,
J. Carolan, Y. Yamamoto, M. Soljacic, and D. Englund. “Towards Large-Scale Photonic
Neural-Network Accelerators.” In 2019 IEEE International Electron Devices Meeting.
IEEE, 2019. https://doi.org/10.1109/iedm19573.2019.8993624.
ieee: R. Hamerly et al., “Towards large-scale photonic neural-network accelerators,”
in 2019 IEEE International Electron Devices Meeting, San Francisco, CA,
United States, 2019.
ista: 'Hamerly R, Sludds A, Bernstein L, Prabhu M, Roques-Carmes C, Carolan J, Yamamoto
Y, Soljacic M, Englund D. 2019. Towards large-scale photonic neural-network accelerators.
2019 IEEE International Electron Devices Meeting. IEDM: International Electron
Devices Meeting.'
mla: Hamerly, R., et al. “Towards Large-Scale Photonic Neural-Network Accelerators.”
2019 IEEE International Electron Devices Meeting, IEEE, 2019, doi:10.1109/iedm19573.2019.8993624.
short: R. Hamerly, A. Sludds, L. Bernstein, M. Prabhu, C. Roques-Carmes, J. Carolan,
Y. Yamamoto, M. Soljacic, D. Englund, in:, 2019 IEEE International Electron Devices
Meeting, IEEE, 2019.
conference:
end_date: 2019-12-11
location: San Francisco, CA, United States
name: 'IEDM: International Electron Devices Meeting'
start_date: 2019-12-07
date_created: 2026-03-30T12:22:47Z
date_published: 2019-12-01T00:00:00Z
date_updated: 2026-05-05T07:39:32Z
day: '01'
doi: 10.1109/iedm19573.2019.8993624
extern: '1'
language:
- iso: eng
month: '12'
oa_version: None
publication: 2019 IEEE International Electron Devices Meeting
publication_identifier:
eisbn:
- '9781728140322'
eissn:
- 2156-017X
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: Towards large-scale photonic neural-network accelerators
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2019'
...