---
_id: '554'
abstract:
- lang: eng
  text: We analyse the canonical Bogoliubov free energy functional in three dimensions
    at low temperatures in the dilute limit. We prove existence of a first-order phase
    transition and, in the limit (Formula presented.), we determine the critical temperature
    to be (Formula presented.) to leading order. Here, (Formula presented.) is the
    critical temperature of the free Bose gas, ρ is the density of the gas and a is
    the scattering length of the pair-interaction potential V. We also prove asymptotic
    expansions for the free energy. In particular, we recover the Lee–Huang–Yang formula
    in the limit (Formula presented.).
article_processing_charge: No
arxiv: 1
author:
- first_name: Marcin M
  full_name: Napiórkowski, Marcin M
  id: 4197AD04-F248-11E8-B48F-1D18A9856A87
  last_name: Napiórkowski
- first_name: Robin
  full_name: Reuvers, Robin
  last_name: Reuvers
- first_name: Jan
  full_name: Solovej, Jan
  last_name: Solovej
citation:
  ama: 'Napiórkowski MM, Reuvers R, Solovej J. The Bogoliubov free energy functional
    II: The dilute Limit. <i>Communications in Mathematical Physics</i>. 2018;360(1):347-403.
    doi:<a href="https://doi.org/10.1007/s00220-017-3064-x">10.1007/s00220-017-3064-x</a>'
  apa: 'Napiórkowski, M. M., Reuvers, R., &#38; Solovej, J. (2018). The Bogoliubov
    free energy functional II: The dilute Limit. <i>Communications in Mathematical
    Physics</i>. Springer. <a href="https://doi.org/10.1007/s00220-017-3064-x">https://doi.org/10.1007/s00220-017-3064-x</a>'
  chicago: 'Napiórkowski, Marcin M, Robin Reuvers, and Jan Solovej. “The Bogoliubov
    Free Energy Functional II: The Dilute Limit.” <i>Communications in Mathematical
    Physics</i>. Springer, 2018. <a href="https://doi.org/10.1007/s00220-017-3064-x">https://doi.org/10.1007/s00220-017-3064-x</a>.'
  ieee: 'M. M. Napiórkowski, R. Reuvers, and J. Solovej, “The Bogoliubov free energy
    functional II: The dilute Limit,” <i>Communications in Mathematical Physics</i>,
    vol. 360, no. 1. Springer, pp. 347–403, 2018.'
  ista: 'Napiórkowski MM, Reuvers R, Solovej J. 2018. The Bogoliubov free energy functional
    II: The dilute Limit. Communications in Mathematical Physics. 360(1), 347–403.'
  mla: 'Napiórkowski, Marcin M., et al. “The Bogoliubov Free Energy Functional II:
    The Dilute Limit.” <i>Communications in Mathematical Physics</i>, vol. 360, no.
    1, Springer, 2018, pp. 347–403, doi:<a href="https://doi.org/10.1007/s00220-017-3064-x">10.1007/s00220-017-3064-x</a>.'
  short: M.M. Napiórkowski, R. Reuvers, J. Solovej, Communications in Mathematical
    Physics 360 (2018) 347–403.
date_created: 2018-12-11T11:47:09Z
date_published: 2018-05-01T00:00:00Z
date_updated: 2025-07-10T11:52:52Z
day: '01'
department:
- _id: RoSe
doi: 10.1007/s00220-017-3064-x
external_id:
  arxiv:
  - '1511.05953'
intvolume: '       360'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1511.05953
month: '05'
oa: 1
oa_version: Submitted Version
page: 347-403
project:
- _id: 25C878CE-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P27533_N27
  name: Structure of the Excitation Spectrum for Many-Body Quantum Systems
publication: Communications in Mathematical Physics
publication_identifier:
  issn:
  - 0010-3616
publication_status: published
publisher: Springer
publist_id: '7260'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The Bogoliubov free energy functional II: The dilute Limit'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 360
year: '2018'
...
---
_id: '555'
abstract:
- lang: eng
  text: Conventional wisdom has it that proteins fold and assemble into definite structures,
    and that this defines their function. Glycosaminoglycans (GAGs) are different.
    In most cases the structures they form have a low degree of order, even when interacting
    with proteins. Here, we discuss how physical features common to all GAGs — hydrophilicity,
    charge, linearity and semi-flexibility — underpin the overall properties of GAG-rich
    matrices. By integrating soft matter physics concepts (e.g. polymer brushes and
    phase separation) with our molecular understanding of GAG–protein interactions,
    we can better comprehend how GAG-rich matrices assemble, what their properties
    are, and how they function. Taking perineuronal nets (PNNs) — a GAG-rich matrix
    enveloping neurons — as a relevant example, we propose that microphase separation
    determines the holey PNN anatomy that is pivotal to PNN functions.
acknowledgement: "This work was supported by the European Research Council [Starting
  Grant 306435 ‘JELLY’; to RPR], the Spanish Ministry of Competitiveness and Innovation
  [MAT2014-54867-R, to RPR], the EPSRC Centre for Doctoral Training in Tissue Engineering
  and Regenerative Medicine — Innovation in Medical and Biological Engineering [EP/L014823/1,
  to JCFK], the Royal Society [RG160410, to JCFK], Wings for Life [WFL-UK-008/15,
  to JCFK] and the European Union, the Operational Programme Research, Development
  and Education in the framework of the project ‘Centre of Reconstructive Neuroscience’
  [CZ.02.1.01/0.0./0.0/15_003/0000419, to JCFK]. AJD would like to thank Arthritis
  Research UK [16539, 19489] and the MRC [76445, G0900538] for funding his work on
  GAG–protein interactions.\r\n"
article_processing_charge: No
article_type: original
author:
- first_name: Ralf
  full_name: Richter, Ralf
  last_name: Richter
- first_name: Natalia
  full_name: Baranova, Natalia
  id: 38661662-F248-11E8-B48F-1D18A9856A87
  last_name: Baranova
  orcid: 0000-0002-3086-9124
- first_name: Anthony
  full_name: Day, Anthony
  last_name: Day
- first_name: Jessica
  full_name: Kwok, Jessica
  last_name: Kwok
citation:
  ama: 'Richter R, Baranova NS, Day A, Kwok J. Glycosaminoglycans in extracellular
    matrix organisation: Are concepts from soft matter physics key to understanding
    the formation of perineuronal nets? <i>Current Opinion in Structural Biology</i>.
    2018;50:65-74. doi:<a href="https://doi.org/10.1016/j.sbi.2017.12.002">10.1016/j.sbi.2017.12.002</a>'
  apa: 'Richter, R., Baranova, N. S., Day, A., &#38; Kwok, J. (2018). Glycosaminoglycans
    in extracellular matrix organisation: Are concepts from soft matter physics key
    to understanding the formation of perineuronal nets? <i>Current Opinion in Structural
    Biology</i>. Elsevier. <a href="https://doi.org/10.1016/j.sbi.2017.12.002">https://doi.org/10.1016/j.sbi.2017.12.002</a>'
  chicago: 'Richter, Ralf, Natalia S. Baranova, Anthony Day, and Jessica Kwok. “Glycosaminoglycans
    in Extracellular Matrix Organisation: Are Concepts from Soft Matter Physics Key
    to Understanding the Formation of Perineuronal Nets?” <i>Current Opinion in Structural
    Biology</i>. Elsevier, 2018. <a href="https://doi.org/10.1016/j.sbi.2017.12.002">https://doi.org/10.1016/j.sbi.2017.12.002</a>.'
  ieee: 'R. Richter, N. S. Baranova, A. Day, and J. Kwok, “Glycosaminoglycans in extracellular
    matrix organisation: Are concepts from soft matter physics key to understanding
    the formation of perineuronal nets?,” <i>Current Opinion in Structural Biology</i>,
    vol. 50. Elsevier, pp. 65–74, 2018.'
  ista: 'Richter R, Baranova NS, Day A, Kwok J. 2018. Glycosaminoglycans in extracellular
    matrix organisation: Are concepts from soft matter physics key to understanding
    the formation of perineuronal nets? Current Opinion in Structural Biology. 50,
    65–74.'
  mla: 'Richter, Ralf, et al. “Glycosaminoglycans in Extracellular Matrix Organisation:
    Are Concepts from Soft Matter Physics Key to Understanding the Formation of Perineuronal
    Nets?” <i>Current Opinion in Structural Biology</i>, vol. 50, Elsevier, 2018,
    pp. 65–74, doi:<a href="https://doi.org/10.1016/j.sbi.2017.12.002">10.1016/j.sbi.2017.12.002</a>.'
  short: R. Richter, N.S. Baranova, A. Day, J. Kwok, Current Opinion in Structural
    Biology 50 (2018) 65–74.
date_created: 2018-12-11T11:47:09Z
date_published: 2018-06-01T00:00:00Z
date_updated: 2023-09-11T14:07:03Z
day: '01'
department:
- _id: MaLo
doi: 10.1016/j.sbi.2017.12.002
external_id:
  isi:
  - '000443661300011'
intvolume: '        50'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://eprints.whiterose.ac.uk/125524/
month: '06'
oa: 1
oa_version: Submitted Version
page: 65 - 74
publication: Current Opinion in Structural Biology
publication_status: published
publisher: Elsevier
publist_id: '7259'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Glycosaminoglycans in extracellular matrix organisation: Are concepts from
  soft matter physics key to understanding the formation of perineuronal nets?'
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 50
year: '2018'
...
---
_id: '556'
abstract:
- lang: eng
  text: 'We investigate the free boundary Schur process, a variant of the Schur process
    introduced by Okounkov and Reshetikhin, where we allow the first and the last
    partitions to be arbitrary (instead of empty in the original setting). The pfaffian
    Schur process, previously studied by several authors, is recovered when just one
    of the boundary partitions is left free. We compute the correlation functions
    of the process in all generality via the free fermion formalism, which we extend
    with the thorough treatment of “free boundary states.” For the case of one free
    boundary, our approach yields a new proof that the process is pfaffian. For the
    case of two free boundaries, we find that the process is not pfaffian, but a closely
    related process is. We also study three different applications of the Schur process
    with one free boundary: fluctuations of symmetrized last passage percolation models,
    limit shapes and processes for symmetric plane partitions and for plane overpartitions.'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Dan
  full_name: Betea, Dan
  last_name: Betea
- first_name: Jeremie
  full_name: Bouttier, Jeremie
  last_name: Bouttier
- first_name: Peter
  full_name: Nejjar, Peter
  id: 4BF426E2-F248-11E8-B48F-1D18A9856A87
  last_name: Nejjar
- first_name: Mirjana
  full_name: Vuletic, Mirjana
  last_name: Vuletic
citation:
  ama: Betea D, Bouttier J, Nejjar P, Vuletic M. The free boundary Schur process and
    applications I. <i>Annales Henri Poincare</i>. 2018;19(12):3663-3742. doi:<a href="https://doi.org/10.1007/s00023-018-0723-1">10.1007/s00023-018-0723-1</a>
  apa: Betea, D., Bouttier, J., Nejjar, P., &#38; Vuletic, M. (2018). The free boundary
    Schur process and applications I. <i>Annales Henri Poincare</i>. Springer Nature.
    <a href="https://doi.org/10.1007/s00023-018-0723-1">https://doi.org/10.1007/s00023-018-0723-1</a>
  chicago: Betea, Dan, Jeremie Bouttier, Peter Nejjar, and Mirjana Vuletic. “The Free
    Boundary Schur Process and Applications I.” <i>Annales Henri Poincare</i>. Springer
    Nature, 2018. <a href="https://doi.org/10.1007/s00023-018-0723-1">https://doi.org/10.1007/s00023-018-0723-1</a>.
  ieee: D. Betea, J. Bouttier, P. Nejjar, and M. Vuletic, “The free boundary Schur
    process and applications I,” <i>Annales Henri Poincare</i>, vol. 19, no. 12. Springer
    Nature, pp. 3663–3742, 2018.
  ista: Betea D, Bouttier J, Nejjar P, Vuletic M. 2018. The free boundary Schur process
    and applications I. Annales Henri Poincare. 19(12), 3663–3742.
  mla: Betea, Dan, et al. “The Free Boundary Schur Process and Applications I.” <i>Annales
    Henri Poincare</i>, vol. 19, no. 12, Springer Nature, 2018, pp. 3663–742, doi:<a
    href="https://doi.org/10.1007/s00023-018-0723-1">10.1007/s00023-018-0723-1</a>.
  short: D. Betea, J. Bouttier, P. Nejjar, M. Vuletic, Annales Henri Poincare 19 (2018)
    3663–3742.
date_created: 2018-12-11T11:47:09Z
date_published: 2018-11-13T00:00:00Z
date_updated: 2025-09-18T07:34:29Z
day: '13'
ddc:
- '500'
department:
- _id: LaEr
- _id: JaMa
doi: 10.1007/s00023-018-0723-1
ec_funded: 1
external_id:
  arxiv:
  - '1704.05809'
  isi:
  - '000450487900003'
file:
- access_level: open_access
  checksum: 0c38abe73569b7166b7487ad5d23cc68
  content_type: application/pdf
  creator: dernst
  date_created: 2019-01-21T15:18:55Z
  date_updated: 2020-07-14T12:47:03Z
  file_id: '5866'
  file_name: 2018_Annales_Betea.pdf
  file_size: 3084674
  relation: main_file
file_date_updated: 2020-07-14T12:47:03Z
has_accepted_license: '1'
intvolume: '        19'
isi: 1
issue: '12'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
page: 3663-3742
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '338804'
  name: Random matrices, universality and disordered quantum systems
- _id: 256E75B8-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '716117'
  name: Optimal Transport and Stochastic Dynamics
publication: Annales Henri Poincare
publication_identifier:
  issn:
  - 1424-0637
publication_status: published
publisher: Springer Nature
publist_id: '7258'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The free boundary Schur process and applications I
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 19
year: '2018'
...
---
_id: '5573'
abstract:
- lang: eng
  text: Graph matching problems for large displacement optical flow of RGB-D images.
article_processing_charge: No
author:
- first_name: Hassan
  full_name: Alhaija, Hassan
  last_name: Alhaija
- first_name: Anita
  full_name: Sellent, Anita
  last_name: Sellent
- first_name: Daniel
  full_name: Kondermann, Daniel
  last_name: Kondermann
- first_name: Carsten
  full_name: Rother, Carsten
  last_name: Rother
citation:
  ama: Alhaija H, Sellent A, Kondermann D, Rother C. Graph matching problems for GraphFlow
    – 6D Large Displacement Scene Flow. 2018. doi:<a href="https://doi.org/10.15479/AT:ISTA:82">10.15479/AT:ISTA:82</a>
  apa: Alhaija, H., Sellent, A., Kondermann, D., &#38; Rother, C. (2018). Graph matching
    problems for GraphFlow – 6D Large Displacement Scene Flow. Institute of Science
    and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:82">https://doi.org/10.15479/AT:ISTA:82</a>
  chicago: Alhaija, Hassan, Anita Sellent, Daniel Kondermann, and Carsten Rother.
    “Graph Matching Problems for GraphFlow – 6D Large Displacement Scene Flow.” Institute
    of Science and Technology Austria, 2018. <a href="https://doi.org/10.15479/AT:ISTA:82">https://doi.org/10.15479/AT:ISTA:82</a>.
  ieee: H. Alhaija, A. Sellent, D. Kondermann, and C. Rother, “Graph matching problems
    for GraphFlow – 6D Large Displacement Scene Flow.” Institute of Science and Technology
    Austria, 2018.
  ista: Alhaija H, Sellent A, Kondermann D, Rother C. 2018. Graph matching problems
    for GraphFlow – 6D Large Displacement Scene Flow, Institute of Science and Technology
    Austria, <a href="https://doi.org/10.15479/AT:ISTA:82">10.15479/AT:ISTA:82</a>.
  mla: Alhaija, Hassan, et al. <i>Graph Matching Problems for GraphFlow – 6D Large
    Displacement Scene Flow</i>. Institute of Science and Technology Austria, 2018,
    doi:<a href="https://doi.org/10.15479/AT:ISTA:82">10.15479/AT:ISTA:82</a>.
  short: H. Alhaija, A. Sellent, D. Kondermann, C. Rother, (2018).
contributor:
- contributor_type: researcher
  first_name: Paul
  id: 446560C6-F248-11E8-B48F-1D18A9856A87
  last_name: Swoboda
datarep_id: '82'
date_created: 2018-12-12T12:31:36Z
date_published: 2018-01-04T00:00:00Z
date_updated: 2024-02-21T13:41:17Z
day: '04'
ddc:
- '001'
department:
- _id: VlKo
doi: 10.15479/AT:ISTA:82
file:
- access_level: open_access
  checksum: 53c17082848e12f3c2e1b4185b578208
  content_type: application/zip
  creator: system
  date_created: 2018-12-12T13:02:34Z
  date_updated: 2020-07-14T12:47:05Z
  file_id: '5600'
  file_name: IST-2018-82-v1+1_GraphFlowMatchingProblems.zip
  file_size: 1737958
  relation: main_file
file_date_updated: 2020-07-14T12:47:05Z
has_accepted_license: '1'
keyword:
- graph matching
- quadratic assignment problem<
license: https://creativecommons.org/publicdomain/zero/1.0/
month: '01'
oa: 1
oa_version: Published Version
publisher: Institute of Science and Technology Austria
related_material:
  link:
  - relation: research_paper
    url: https://doi.org/10.1007/978-3-319-24947-6_23
status: public
title: Graph matching problems for GraphFlow – 6D Large Displacement Scene Flow
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2018'
...
---
_id: '5583'
abstract:
- lang: eng
  text: "Data and scripts are provided in support of the manuscript \"Efficient inference
    of paternity and sibship inference given known maternity via hierarchical clustering\",
    and the associated Python package FAPS, available from www.github.com/ellisztamas/faps.\r\n\r\nSimulation
    scripts cover:\r\n1. Performance under different mating scenarios.\r\n2. Comparison
    with Colony2.\r\n3. Effect of changing the number of Monte Carlo draws\r\n\r\nThe
    final script covers the analysis of half-sib arrays from wild-pollinated seed
    in an Antirrhinum majus hybrid zone."
article_processing_charge: No
author:
- first_name: Thomas
  full_name: Ellis, Thomas
  id: 3153D6D4-F248-11E8-B48F-1D18A9856A87
  last_name: Ellis
  orcid: 0000-0002-8511-0254
citation:
  ama: Ellis T. Data and Python scripts supporting Python package FAPS. 2018. doi:<a
    href="https://doi.org/10.15479/AT:ISTA:95">10.15479/AT:ISTA:95</a>
  apa: Ellis, T. (2018). Data and Python scripts supporting Python package FAPS. Institute
    of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:95">https://doi.org/10.15479/AT:ISTA:95</a>
  chicago: Ellis, Thomas. “Data and Python Scripts Supporting Python Package FAPS.”
    Institute of Science and Technology Austria, 2018. <a href="https://doi.org/10.15479/AT:ISTA:95">https://doi.org/10.15479/AT:ISTA:95</a>.
  ieee: T. Ellis, “Data and Python scripts supporting Python package FAPS.” Institute
    of Science and Technology Austria, 2018.
  ista: Ellis T. 2018. Data and Python scripts supporting Python package FAPS, Institute
    of Science and Technology Austria, <a href="https://doi.org/10.15479/AT:ISTA:95">10.15479/AT:ISTA:95</a>.
  mla: Ellis, Thomas. <i>Data and Python Scripts Supporting Python Package FAPS</i>.
    Institute of Science and Technology Austria, 2018, doi:<a href="https://doi.org/10.15479/AT:ISTA:95">10.15479/AT:ISTA:95</a>.
  short: T. Ellis, (2018).
contributor:
- first_name: David
  id: 419049E2-F248-11E8-B48F-1D18A9856A87
  last_name: Field
- first_name: Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
datarep_id: '95'
date_created: 2018-12-12T12:31:39Z
date_published: 2018-02-12T00:00:00Z
date_updated: 2025-04-15T07:11:03Z
day: '12'
department:
- _id: NiBa
doi: 10.15479/AT:ISTA:95
file:
- access_level: open_access
  checksum: fc6aab51439f2622ba6df8632e66fd4f
  content_type: text/csv
  creator: system
  date_created: 2018-12-12T13:02:41Z
  date_updated: 2020-07-14T12:47:07Z
  file_id: '5606'
  file_name: IST-2018-95-v1+1_amajus_GPS_2012.csv
  file_size: 122048
  relation: main_file
- access_level: open_access
  checksum: 92347586ae4f8a6eb7c04354797bf314
  content_type: text/csv
  creator: system
  date_created: 2018-12-12T13:02:42Z
  date_updated: 2020-07-14T12:47:07Z
  file_id: '5607'
  file_name: IST-2018-95-v1+2_offspring_SNPs_2012.csv
  file_size: 235980
  relation: main_file
- access_level: open_access
  checksum: 3300813645a54e6c5c39f41917228354
  content_type: text/csv
  creator: system
  date_created: 2018-12-12T13:02:43Z
  date_updated: 2020-07-14T12:47:07Z
  file_id: '5608'
  file_name: IST-2018-95-v1+3_parents_SNPs_2012.csv
  file_size: 311712
  relation: main_file
- access_level: open_access
  checksum: e739fc473567fd8f39438b445fc46147
  content_type: application/zip
  creator: system
  date_created: 2018-12-12T13:02:44Z
  date_updated: 2020-07-14T12:47:07Z
  file_id: '5609'
  file_name: IST-2018-95-v1+4_faps_scripts.zip
  file_size: 342090
  relation: main_file
file_date_updated: 2020-07-14T12:47:07Z
has_accepted_license: '1'
month: '02'
oa: 1
oa_version: Published Version
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '286'
    relation: research_paper
    status: public
status: public
title: Data and Python scripts supporting Python package FAPS
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2018'
...
---
_id: '5584'
abstract:
- lang: eng
  text: "This package contains data for the publication \"Nonlinear decoding of a
    complex movie from the mammalian retina\" by Deny S. et al, PLOS Comput Biol (2018).
    \r\n\r\nThe data consists of\r\n(i) 91 spike sorted, isolated rat retinal ganglion
    cells that pass stability and quality criteria, recorded on the multi-electrode
    array, in response to the presentation of the complex movie with many randomly
    moving dark discs. The responses are represented as 648000 x 91 binary matrix,
    where the first index indicates the timebin of duration 12.5 ms, and the second
    index the neural identity. The matrix entry is 0/1 if the neuron didn't/did spike
    in the particular time bin.\r\n(ii) README file and a graphical illustration of
    the structure of the experiment, specifying how the 648000 timebins are split
    into epochs where 1, 2, 4, or 10 discs  were displayed, and which stimulus segments
    are exact repeats or unique ball trajectories.\r\n(iii) a 648000 x 400 matrix
    of luminance traces for each of the 20 x 20 positions (\"sites\") in the movie
    frame, with time that is locked to the recorded raster. The luminance traces are
    produced as described in the manuscript by filtering the raw disc movie with a
    small gaussian spatial kernel. "
article_processing_charge: No
author:
- first_name: Stephane
  full_name: Deny, Stephane
  last_name: Deny
- first_name: Olivier
  full_name: Marre, Olivier
  last_name: Marre
- first_name: Vicente
  full_name: Botella-Soler, Vicente
  last_name: Botella-Soler
- first_name: Georg S
  full_name: Martius, Georg S
  id: 3A276B68-F248-11E8-B48F-1D18A9856A87
  last_name: Martius
- first_name: Gasper
  full_name: Tkacik, Gasper
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkacik
  orcid: 0000-0002-6699-1455
citation:
  ama: Deny S, Marre O, Botella-Soler V, Martius GS, Tkačik G. Nonlinear decoding
    of a complex movie from the mammalian retina. 2018. doi:<a href="https://doi.org/10.15479/AT:ISTA:98">10.15479/AT:ISTA:98</a>
  apa: Deny, S., Marre, O., Botella-Soler, V., Martius, G. S., &#38; Tkačik, G. (2018).
    Nonlinear decoding of a complex movie from the mammalian retina. Institute of
    Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:98">https://doi.org/10.15479/AT:ISTA:98</a>
  chicago: Deny, Stephane, Olivier Marre, Vicente Botella-Soler, Georg S Martius,
    and Gašper Tkačik. “Nonlinear Decoding of a Complex Movie from the Mammalian Retina.”
    Institute of Science and Technology Austria, 2018. <a href="https://doi.org/10.15479/AT:ISTA:98">https://doi.org/10.15479/AT:ISTA:98</a>.
  ieee: S. Deny, O. Marre, V. Botella-Soler, G. S. Martius, and G. Tkačik, “Nonlinear
    decoding of a complex movie from the mammalian retina.” Institute of Science and
    Technology Austria, 2018.
  ista: Deny S, Marre O, Botella-Soler V, Martius GS, Tkačik G. 2018. Nonlinear decoding
    of a complex movie from the mammalian retina, Institute of Science and Technology
    Austria, <a href="https://doi.org/10.15479/AT:ISTA:98">10.15479/AT:ISTA:98</a>.
  mla: Deny, Stephane, et al. <i>Nonlinear Decoding of a Complex Movie from the Mammalian
    Retina</i>. Institute of Science and Technology Austria, 2018, doi:<a href="https://doi.org/10.15479/AT:ISTA:98">10.15479/AT:ISTA:98</a>.
  short: S. Deny, O. Marre, V. Botella-Soler, G.S. Martius, G. Tkačik, (2018).
datarep_id: '98'
date_created: 2018-12-12T12:31:39Z
date_published: 2018-03-29T00:00:00Z
date_updated: 2025-04-15T08:18:24Z
day: '29'
ddc:
- '570'
department:
- _id: ChLa
- _id: GaTk
doi: 10.15479/AT:ISTA:98
file:
- access_level: open_access
  checksum: 6808748837b9afbbbabc2a356ca2b88a
  content_type: application/octet-stream
  creator: system
  date_created: 2018-12-12T13:02:24Z
  date_updated: 2020-07-14T12:47:07Z
  file_id: '5590'
  file_name: IST-2018-98-v1+1_BBalls_area2_tile2_20x20.mat
  file_size: 1142543971
  relation: main_file
- access_level: open_access
  checksum: d6d6cd07743038fe3a12352983fcf9dd
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T13:02:25Z
  date_updated: 2020-07-14T12:47:07Z
  file_id: '5591'
  file_name: IST-2018-98-v1+2_ExperimentStructure.pdf
  file_size: 702336
  relation: main_file
- access_level: open_access
  checksum: 0c9cfb4dab35bb3dc25a04395600b1c8
  content_type: application/octet-stream
  creator: system
  date_created: 2018-12-12T13:02:26Z
  date_updated: 2020-07-14T12:47:07Z
  file_id: '5592'
  file_name: IST-2018-98-v1+3_GoodLocations_area2_20x20.mat
  file_size: 432
  relation: main_file
- access_level: open_access
  checksum: 2a83b011012e21e934b4596285b1a183
  content_type: text/plain
  creator: system
  date_created: 2018-12-12T13:02:26Z
  date_updated: 2020-07-14T12:47:07Z
  file_id: '5593'
  file_name: IST-2018-98-v1+4_README.txt
  file_size: 986
  relation: main_file
file_date_updated: 2020-07-14T12:47:07Z
has_accepted_license: '1'
keyword:
- retina
- decoding
- regression
- neural networks
- complex stimulus
month: '03'
oa: 1
oa_version: Published Version
project:
- _id: 254D1A94-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P 25651-N26
  name: Sensitivity to higher-order statistics in natural scenes
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '292'
    relation: used_in_publication
    status: public
status: public
title: Nonlinear decoding of a complex movie from the mammalian retina
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2018'
...
---
_id: '5586'
abstract:
- lang: eng
  text: Input files and scripts from "Evolution of gene dosage on the Z-chromosome
    of schistosome parasites" by Picard M.A.L., et al (2018).
article_processing_charge: No
author:
- first_name: Beatriz
  full_name: Vicoso, Beatriz
  id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
  last_name: Vicoso
  orcid: 0000-0002-4579-8306
citation:
  ama: Vicoso B. Input files and scripts from “Evolution of gene dosage on the Z-chromosome
    of schistosome parasites” by Picard M.A.L., et al (2018). 2018. doi:<a href="https://doi.org/10.15479/AT:ISTA:109">10.15479/AT:ISTA:109</a>
  apa: Vicoso, B. (2018). Input files and scripts from “Evolution of gene dosage on
    the Z-chromosome of schistosome parasites” by Picard M.A.L., et al (2018). Institute
    of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:109">https://doi.org/10.15479/AT:ISTA:109</a>
  chicago: Vicoso, Beatriz. “Input Files and Scripts from ‘Evolution of Gene Dosage
    on the Z-Chromosome of Schistosome Parasites’ by Picard M.A.L., et Al (2018).”
    Institute of Science and Technology Austria, 2018. <a href="https://doi.org/10.15479/AT:ISTA:109">https://doi.org/10.15479/AT:ISTA:109</a>.
  ieee: B. Vicoso, “Input files and scripts from ‘Evolution of gene dosage on the
    Z-chromosome of schistosome parasites’ by Picard M.A.L., et al (2018).” Institute
    of Science and Technology Austria, 2018.
  ista: Vicoso B. 2018. Input files and scripts from ‘Evolution of gene dosage on
    the Z-chromosome of schistosome parasites’ by Picard M.A.L., et al (2018), Institute
    of Science and Technology Austria, <a href="https://doi.org/10.15479/AT:ISTA:109">10.15479/AT:ISTA:109</a>.
  mla: Vicoso, Beatriz. <i>Input Files and Scripts from “Evolution of Gene Dosage
    on the Z-Chromosome of Schistosome Parasites” by Picard M.A.L., et Al (2018)</i>.
    Institute of Science and Technology Austria, 2018, doi:<a href="https://doi.org/10.15479/AT:ISTA:109">10.15479/AT:ISTA:109</a>.
  short: B. Vicoso, (2018).
contributor:
- first_name: Marion A
  id: 2C921A7A-F248-11E8-B48F-1D18A9856A87
  last_name: Picard
  orcid: 0000-0002-8101-2518
datarep_id: '109'
date_created: 2018-12-12T12:31:40Z
date_published: 2018-07-24T00:00:00Z
date_updated: 2025-04-15T08:18:37Z
day: '24'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.15479/AT:ISTA:109
file:
- access_level: open_access
  checksum: e60b484bd6f55c08eb66a189cb72c923
  content_type: application/zip
  creator: system
  date_created: 2018-12-12T13:02:35Z
  date_updated: 2020-07-14T12:47:08Z
  file_id: '5601'
  file_name: IST-2018-109-v1+1_SupplementaryMethods.zip
  file_size: 11918144
  relation: main_file
file_date_updated: 2020-07-14T12:47:08Z
has_accepted_license: '1'
keyword:
- schistosoma
- Z-chromosome
- gene expression
month: '07'
oa: 1
oa_version: Published Version
project:
- _id: 250ED89C-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P28842-B22
  name: Sex chromosome evolution under male- and female- heterogamety
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '131'
    relation: research_paper
    status: public
status: public
title: Input files and scripts from "Evolution of gene dosage on the Z-chromosome
  of schistosome parasites" by Picard M.A.L., et al (2018)
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2018'
...
---
_id: '5587'
abstract:
- lang: eng
  text: "Supporting material to the article \r\nSTATISTICAL MECHANICS FOR METABOLIC
    NETWORKS IN STEADY-STATE GROWTH\r\n\r\nboundscoli.dat\r\nFlux Bounds of the E.
    coli catabolic core model iAF1260 in a glucose limited minimal medium. \r\n\r\npolcoli.dat\r\nMatrix
    enconding the polytope of the E. coli catabolic core model iAF1260 in a glucose
    limited minimal medium, \r\nobtained from the soichiometric matrix by standard
    linear algebra  (reduced row echelon form).\r\n\r\nellis.dat\r\nApproximate Lowner-John
    ellipsoid rounding the polytope of the E. coli catabolic core model iAF1260 in
    a glucose limited minimal medium\r\nobtained with the Lovasz method.\r\n\r\npoint0.dat\r\nCenter
    of the approximate Lowner-John ellipsoid rounding the polytope of the E. coli
    catabolic core model iAF1260 in a glucose limited minimal medium\r\nobtained with
    the Lovasz method.\r\n\r\nlovasz.cpp  \r\nThis c++ code file receives in input
    the polytope of the feasible steady states of a metabolic network, \r\n(matrix
    and bounds), and it gives in output an approximate Lowner-John ellipsoid rounding
    the polytope\r\nwith the Lovasz method \r\nNB inputs are referred by defaults
    to the catabolic core of the E.Coli network iAF1260. \r\nFor further details we
    refer to  PLoS ONE 10.4 e0122670 (2015).\r\n\r\nsampleHRnew.cpp  \r\nThis c++
    code file receives in input the polytope of the feasible steady states of a metabolic
    network, \r\n(matrix and bounds), the ellipsoid rounding the polytope, a point
    inside and  \r\nit gives in output a max entropy sampling at fixed average growth
    rate \r\nof the steady states by performing an Hit-and-Run Monte Carlo Markov
    chain.\r\nNB inputs are referred by defaults to the catabolic core of the E.Coli
    network iAF1260. \r\nFor further details we refer to  PLoS ONE 10.4 e0122670 (2015)."
article_processing_charge: No
author:
- first_name: Daniele
  full_name: De Martino, Daniele
  id: 3FF5848A-F248-11E8-B48F-1D18A9856A87
  last_name: De Martino
  orcid: 0000-0002-5214-4706
- first_name: Gasper
  full_name: Tkacik, Gasper
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkacik
  orcid: 0000-0002-6699-1455
citation:
  ama: De Martino D, Tkačik G. Supporting materials “STATISTICAL MECHANICS FOR METABOLIC
    NETWORKS IN STEADY-STATE GROWTH.” 2018. doi:<a href="https://doi.org/10.15479/AT:ISTA:62">10.15479/AT:ISTA:62</a>
  apa: De Martino, D., &#38; Tkačik, G. (2018). Supporting materials “STATISTICAL
    MECHANICS FOR METABOLIC NETWORKS IN STEADY-STATE GROWTH.” Institute of Science
    and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:62">https://doi.org/10.15479/AT:ISTA:62</a>
  chicago: De Martino, Daniele, and Gašper Tkačik. “Supporting Materials ‘STATISTICAL
    MECHANICS FOR METABOLIC NETWORKS IN STEADY-STATE GROWTH.’” Institute of Science
    and Technology Austria, 2018. <a href="https://doi.org/10.15479/AT:ISTA:62">https://doi.org/10.15479/AT:ISTA:62</a>.
  ieee: D. De Martino and G. Tkačik, “Supporting materials ‘STATISTICAL MECHANICS
    FOR METABOLIC NETWORKS IN STEADY-STATE GROWTH.’” Institute of Science and Technology
    Austria, 2018.
  ista: De Martino D, Tkačik G. 2018. Supporting materials ‘STATISTICAL MECHANICS
    FOR METABOLIC NETWORKS IN STEADY-STATE GROWTH’, Institute of Science and Technology
    Austria, <a href="https://doi.org/10.15479/AT:ISTA:62">10.15479/AT:ISTA:62</a>.
  mla: De Martino, Daniele, and Gašper Tkačik. <i>Supporting Materials “STATISTICAL
    MECHANICS FOR METABOLIC NETWORKS IN STEADY-STATE GROWTH.”</i> Institute of Science
    and Technology Austria, 2018, doi:<a href="https://doi.org/10.15479/AT:ISTA:62">10.15479/AT:ISTA:62</a>.
  short: D. De Martino, G. Tkačik, (2018).
datarep_id: '111'
date_created: 2018-12-12T12:31:41Z
date_published: 2018-09-21T00:00:00Z
date_updated: 2025-04-15T06:50:08Z
day: '21'
ddc:
- '530'
department:
- _id: GaTk
doi: 10.15479/AT:ISTA:62
ec_funded: 1
file:
- access_level: open_access
  checksum: 97992e3e8cf8544ec985a48971708726
  content_type: application/zip
  creator: system
  date_created: 2018-12-12T13:05:13Z
  date_updated: 2020-07-14T12:47:08Z
  file_id: '5641'
  file_name: IST-2018-111-v1+1_CODES.zip
  file_size: 14376
  relation: main_file
file_date_updated: 2020-07-14T12:47:08Z
has_accepted_license: '1'
keyword:
- metabolic networks
- e.coli core
- maximum entropy
- monte carlo markov chain sampling
- ellipsoidal rounding
month: '09'
oa: 1
oa_version: Published Version
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
- _id: 254E9036-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P28844-B27
  name: Biophysics of information processing in gene regulation
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '161'
    relation: research_paper
    status: public
status: public
title: Supporting materials "STATISTICAL MECHANICS FOR METABOLIC NETWORKS IN STEADY-STATE
  GROWTH"
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2018'
...
---
_id: '5588'
abstract:
- lang: eng
  text: Script to perform a simple exponential lifetime fit of a ROI on time stacks
    acquired with a FLIM X16 TCSPC detector (+example data)
article_processing_charge: No
author:
- first_name: Robert
  full_name: Hauschild, Robert
  id: 4E01D6B4-F248-11E8-B48F-1D18A9856A87
  last_name: Hauschild
  orcid: 0000-0001-9843-3522
citation:
  ama: Hauschild R. Fluorescence lifetime analysis of FLIM X16 TCSPC data. 2018. doi:<a
    href="https://doi.org/10.15479/AT:ISTA:0113">10.15479/AT:ISTA:0113</a>
  apa: Hauschild, R. (2018). Fluorescence lifetime analysis of FLIM X16 TCSPC data.
    Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:0113">https://doi.org/10.15479/AT:ISTA:0113</a>
  chicago: Hauschild, Robert. “Fluorescence Lifetime Analysis of FLIM X16 TCSPC Data.”
    Institute of Science and Technology Austria, 2018. <a href="https://doi.org/10.15479/AT:ISTA:0113">https://doi.org/10.15479/AT:ISTA:0113</a>.
  ieee: R. Hauschild, “Fluorescence lifetime analysis of FLIM X16 TCSPC data.” Institute
    of Science and Technology Austria, 2018.
  ista: Hauschild R. 2018. Fluorescence lifetime analysis of FLIM X16 TCSPC data,
    Institute of Science and Technology Austria, <a href="https://doi.org/10.15479/AT:ISTA:0113">10.15479/AT:ISTA:0113</a>.
  mla: Hauschild, Robert. <i>Fluorescence Lifetime Analysis of FLIM X16 TCSPC Data</i>.
    Institute of Science and Technology Austria, 2018, doi:<a href="https://doi.org/10.15479/AT:ISTA:0113">10.15479/AT:ISTA:0113</a>.
  short: R. Hauschild, (2018).
datarep_id: '113'
date_created: 2018-12-12T12:31:41Z
date_published: 2018-11-07T00:00:00Z
date_updated: 2024-02-21T13:44:21Z
day: '07'
ddc:
- '570'
department:
- _id: Bio
doi: 10.15479/AT:ISTA:0113
file:
- access_level: open_access
  checksum: a4e160054c9114600624cf89a925fd7d
  content_type: application/x-zip-compressed
  creator: rhauschild
  date_created: 2019-04-11T18:15:01Z
  date_updated: 2020-07-14T12:47:08Z
  file_id: '6296'
  file_name: IST-2018-113-v1+1_FLIMX16TCSPCLifeTimeFit.zip
  file_size: 47866557
  relation: main_file
file_date_updated: 2020-07-14T12:47:08Z
has_accepted_license: '1'
keyword:
- FLIM
- FRET
- fluorescence lifetime imaging
month: '11'
oa: 1
oa_version: Published Version
publisher: Institute of Science and Technology Austria
status: public
title: Fluorescence lifetime analysis of FLIM X16 TCSPC data
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2018'
...
---
_id: '562'
abstract:
- lang: eng
  text: Primary neuronal cell culture preparations are widely used to investigate
    synaptic functions. This chapter describes a detailed protocol for the preparation
    of a neuronal cell culture in which giant calyx-type synaptic terminals are formed.
    This chapter also presents detailed protocols for utilizing the main technical
    advantages provided by such a preparation, namely, labeling and imaging of synaptic
    organelles and electrophysiological recordings directly from presynaptic terminals.
alternative_title:
- Methods in Molecular Biology
article_processing_charge: No
author:
- first_name: Dimitar
  full_name: Dimitrov, Dimitar
  last_name: Dimitrov
- first_name: Laurent
  full_name: Guillaud, Laurent
  last_name: Guillaud
- first_name: Kohgaku
  full_name: Eguchi, Kohgaku
  id: 2B7846DC-F248-11E8-B48F-1D18A9856A87
  last_name: Eguchi
  orcid: 0000-0002-6170-2546
- first_name: Tomoyuki
  full_name: Takahashi, Tomoyuki
  last_name: Takahashi
citation:
  ama: 'Dimitrov D, Guillaud L, Eguchi K, Takahashi T. Culture of mouse giant central
    nervous system synapses and application for imaging and electrophysiological analyses.
    In: Skaper SD, ed. <i>Neurotrophic Factors</i>. Vol 1727. Springer; 2018:201-215.
    doi:<a href="https://doi.org/10.1007/978-1-4939-7571-6_15">10.1007/978-1-4939-7571-6_15</a>'
  apa: Dimitrov, D., Guillaud, L., Eguchi, K., &#38; Takahashi, T. (2018). Culture
    of mouse giant central nervous system synapses and application for imaging and
    electrophysiological analyses. In S. D. Skaper (Ed.), <i>Neurotrophic Factors</i>
    (Vol. 1727, pp. 201–215). Springer. <a href="https://doi.org/10.1007/978-1-4939-7571-6_15">https://doi.org/10.1007/978-1-4939-7571-6_15</a>
  chicago: Dimitrov, Dimitar, Laurent Guillaud, Kohgaku Eguchi, and Tomoyuki Takahashi.
    “Culture of Mouse Giant Central Nervous System Synapses and Application for Imaging
    and Electrophysiological Analyses.” In <i>Neurotrophic Factors</i>, edited by
    Stephen D. Skaper, 1727:201–15. Springer, 2018. <a href="https://doi.org/10.1007/978-1-4939-7571-6_15">https://doi.org/10.1007/978-1-4939-7571-6_15</a>.
  ieee: D. Dimitrov, L. Guillaud, K. Eguchi, and T. Takahashi, “Culture of mouse giant
    central nervous system synapses and application for imaging and electrophysiological
    analyses,” in <i>Neurotrophic Factors</i>, vol. 1727, S. D. Skaper, Ed. Springer,
    2018, pp. 201–215.
  ista: 'Dimitrov D, Guillaud L, Eguchi K, Takahashi T. 2018.Culture of mouse giant
    central nervous system synapses and application for imaging and electrophysiological
    analyses. In: Neurotrophic Factors. Methods in Molecular Biology, vol. 1727, 201–215.'
  mla: Dimitrov, Dimitar, et al. “Culture of Mouse Giant Central Nervous System Synapses
    and Application for Imaging and Electrophysiological Analyses.” <i>Neurotrophic
    Factors</i>, edited by Stephen D. Skaper, vol. 1727, Springer, 2018, pp. 201–15,
    doi:<a href="https://doi.org/10.1007/978-1-4939-7571-6_15">10.1007/978-1-4939-7571-6_15</a>.
  short: D. Dimitrov, L. Guillaud, K. Eguchi, T. Takahashi, in:, S.D. Skaper (Ed.),
    Neurotrophic Factors, Springer, 2018, pp. 201–215.
date_created: 2018-12-11T11:47:11Z
date_published: 2018-01-01T00:00:00Z
date_updated: 2021-01-12T08:03:05Z
day: '01'
ddc:
- '570'
department:
- _id: RySh
doi: 10.1007/978-1-4939-7571-6_15
editor:
- first_name: Stephen D.
  full_name: Skaper, Stephen D.
  last_name: Skaper
external_id:
  pmid:
  - '29222783'
file:
- access_level: open_access
  checksum: 8aa174ca65a56fbb19e9f88cff3ac3fd
  content_type: application/pdf
  creator: dernst
  date_created: 2019-11-19T07:47:43Z
  date_updated: 2020-07-14T12:47:09Z
  file_id: '7046'
  file_name: 2018_NeurotrophicFactors_Dimitrov.pdf
  file_size: 787407
  relation: main_file
file_date_updated: 2020-07-14T12:47:09Z
has_accepted_license: '1'
intvolume: '      1727'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Submitted Version
page: 201 - 215
pmid: 1
publication: Neurotrophic Factors
publication_status: published
publisher: Springer
publist_id: '7252'
quality_controlled: '1'
scopus_import: 1
status: public
title: Culture of mouse giant central nervous system synapses and application for
  imaging and electrophysiological analyses
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1727
year: '2018'
...
---
_id: '564'
abstract:
- lang: eng
  text: "Maladapted individuals can only colonise a new habitat if they can evolve
    a\r\npositive growth rate fast enough to avoid extinction, a process known as
    evolutionary\r\nrescue. We treat log fitness at low density in the new habitat
    as a\r\nsingle polygenic trait and thus use the infinitesimal model to follow
    the evolution\r\nof the growth rate; this assumes that the trait values of offspring
    of a\r\nsexual union are normally distributed around the mean of the parents’
    trait\r\nvalues, with variance that depends only on the parents’ relatedness.
    The\r\nprobability that a single migrant can establish depends on just two parameters:\r\nthe
    mean and genetic variance of the trait in the source population.\r\nThe chance
    of success becomes small if migrants come from a population\r\nwith mean growth
    rate in the new habitat more than a few standard deviations\r\nbelow zero; this
    chance depends roughly equally on the probability\r\nthat the initial founder
    is unusually fit, and on the subsequent increase in\r\ngrowth rate of its offspring
    as a result of selection. The loss of genetic variation\r\nduring the founding
    event is substantial, but highly variable. With\r\ncontinued migration at rate
    M, establishment is inevitable; when migration\r\nis rare, the expected time to
    establishment decreases inversely with M.\r\nHowever, above a threshold migration
    rate, the population may be trapped\r\nin a ‘sink’ state, in which adaptation
    is held back by gene flow; above this\r\nthreshold, the expected time to establishment
    increases exponentially with M. This threshold behaviour is captured by a deterministic
    approximation,\r\nwhich assumes a Gaussian distribution of the trait in the founder
    population\r\nwith mean and variance evolving deterministically. By assuming a
    constant\r\ngenetic variance, we also develop a diffusion approximation for the
    joint distribution\r\nof population size and trait mean, which extends to include
    stabilising\r\nselection and density regulation. Divergence of the population
    from its\r\nancestors causes partial reproductive isolation, which we measure
    through\r\nthe reproductive value of migrants into the newly established population."
article_processing_charge: No
article_type: original
author:
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Alison
  full_name: Etheridge, Alison
  last_name: Etheridge
citation:
  ama: Barton NH, Etheridge A. Establishment in a new habitat by polygenic adaptation.
    <i>Theoretical Population Biology</i>. 2018;122(7):110-127. doi:<a href="https://doi.org/10.1016/j.tpb.2017.11.007">10.1016/j.tpb.2017.11.007</a>
  apa: Barton, N. H., &#38; Etheridge, A. (2018). Establishment in a new habitat by
    polygenic adaptation. <i>Theoretical Population Biology</i>. Academic Press. <a
    href="https://doi.org/10.1016/j.tpb.2017.11.007">https://doi.org/10.1016/j.tpb.2017.11.007</a>
  chicago: Barton, Nicholas H, and Alison Etheridge. “Establishment in a New Habitat
    by Polygenic Adaptation.” <i>Theoretical Population Biology</i>. Academic Press,
    2018. <a href="https://doi.org/10.1016/j.tpb.2017.11.007">https://doi.org/10.1016/j.tpb.2017.11.007</a>.
  ieee: N. H. Barton and A. Etheridge, “Establishment in a new habitat by polygenic
    adaptation,” <i>Theoretical Population Biology</i>, vol. 122, no. 7. Academic
    Press, pp. 110–127, 2018.
  ista: Barton NH, Etheridge A. 2018. Establishment in a new habitat by polygenic
    adaptation. Theoretical Population Biology. 122(7), 110–127.
  mla: Barton, Nicholas H., and Alison Etheridge. “Establishment in a New Habitat
    by Polygenic Adaptation.” <i>Theoretical Population Biology</i>, vol. 122, no.
    7, Academic Press, 2018, pp. 110–27, doi:<a href="https://doi.org/10.1016/j.tpb.2017.11.007">10.1016/j.tpb.2017.11.007</a>.
  short: N.H. Barton, A. Etheridge, Theoretical Population Biology 122 (2018) 110–127.
date_created: 2018-12-11T11:47:12Z
date_published: 2018-07-01T00:00:00Z
date_updated: 2025-04-15T07:11:04Z
day: '01'
ddc:
- '519'
- '576'
department:
- _id: NiBa
doi: 10.1016/j.tpb.2017.11.007
ec_funded: 1
external_id:
  isi:
  - '000440392900014'
file:
- access_level: open_access
  checksum: 0b96f6db47e3e91b5e7d103b847c239d
  content_type: application/pdf
  creator: nbarton
  date_created: 2019-12-21T09:36:39Z
  date_updated: 2020-07-14T12:47:09Z
  file_id: '7199'
  file_name: bartonetheridge.pdf
  file_size: 2287682
  relation: main_file
file_date_updated: 2020-07-14T12:47:09Z
has_accepted_license: '1'
intvolume: '       122'
isi: 1
issue: '7'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Submitted Version
page: 110-127
project:
- _id: 25B07788-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '250152'
  name: Limits to selection in biology and in evolutionary computation
publication: Theoretical Population Biology
publication_status: published
publisher: Academic Press
publist_id: '7250'
quality_controlled: '1'
related_material:
  record:
  - id: '9842'
    relation: research_data
    status: public
scopus_import: '1'
status: public
title: Establishment in a new habitat by polygenic adaptation
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 122
year: '2018'
...
---
_id: '565'
abstract:
- lang: eng
  text: 'We re-examine the model of Kirkpatrick and Barton for the spread of an inversion
    into a local population. This model assumes that local selection maintains alleles
    at two or more loci, despite immigration of alternative alleles at these loci
    from another population. We show that an inversion is favored because it prevents
    the breakdown of linkage disequilibrium generated by migration; the selective
    advantage of an inversion is proportional to the amount of recombination between
    the loci involved, as in other cases where inversions are selected for. We derive
    expressions for the rate of spread of an inversion; when the loci covered by the
    inversion are tightly linked, these conditions deviate substantially from those
    proposed previously, and imply that an inversion can then have only a small advantage. '
article_processing_charge: No
article_type: original
author:
- first_name: Brian
  full_name: Charlesworth, Brian
  last_name: Charlesworth
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
citation:
  ama: Charlesworth B, Barton NH. The spread of an inversion with migration and selection.
    <i>Genetics</i>. 2018;208(1):377-382. doi:<a href="https://doi.org/10.1534/genetics.117.300426">10.1534/genetics.117.300426</a>
  apa: Charlesworth, B., &#38; Barton, N. H. (2018). The spread of an inversion with
    migration and selection. <i>Genetics</i>. Genetics Society of America. <a href="https://doi.org/10.1534/genetics.117.300426">https://doi.org/10.1534/genetics.117.300426</a>
  chicago: Charlesworth, Brian, and Nicholas H Barton. “The Spread of an Inversion
    with Migration and Selection.” <i>Genetics</i>. Genetics Society of America, 2018.
    <a href="https://doi.org/10.1534/genetics.117.300426">https://doi.org/10.1534/genetics.117.300426</a>.
  ieee: B. Charlesworth and N. H. Barton, “The spread of an inversion with migration
    and selection,” <i>Genetics</i>, vol. 208, no. 1. Genetics Society of America,
    pp. 377–382, 2018.
  ista: Charlesworth B, Barton NH. 2018. The spread of an inversion with migration
    and selection. Genetics. 208(1), 377–382.
  mla: Charlesworth, Brian, and Nicholas H. Barton. “The Spread of an Inversion with
    Migration and Selection.” <i>Genetics</i>, vol. 208, no. 1, Genetics Society of
    America, 2018, pp. 377–82, doi:<a href="https://doi.org/10.1534/genetics.117.300426">10.1534/genetics.117.300426</a>.
  short: B. Charlesworth, N.H. Barton, Genetics 208 (2018) 377–382.
date_created: 2018-12-11T11:47:12Z
date_published: 2018-01-01T00:00:00Z
date_updated: 2025-06-03T11:31:54Z
day: '01'
department:
- _id: NiBa
doi: 10.1534/genetics.117.300426
external_id:
  isi:
  - '000419356300025'
  pmid:
  - '29158424'
intvolume: '       208'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753870/
month: '01'
oa: 1
oa_version: Published Version
page: 377 - 382
pmid: 1
publication: Genetics
publication_status: published
publisher: Genetics Society of America
publist_id: '7249'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The spread of an inversion with migration and selection
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 208
year: '2018'
...
---
_id: '5673'
abstract:
- lang: eng
  text: Cell polarity, manifested by the localization of proteins to distinct polar
    plasma membrane domains, is a key prerequisite of multicellular life. In plants,
    PIN auxin transporters are prominent polarity markers crucial for a plethora of
    developmental processes. Cell polarity mechanisms in plants are distinct from
    other eukaryotes and still largely elusive. In particular, how the cell polarities
    are propagated and maintained following cell division remains unknown. Plant cytokinesis
    is orchestrated by the cell plate—a transient centrifugally growing endomembrane
    compartment ultimately forming the cross wall1. Trafficking of polar membrane
    proteins is typically redirected to the cell plate, and these will consequently
    have opposite polarity in at least one of the daughter cells2–5. Here, we provide
    mechanistic insights into post-cytokinetic re-establishment of cell polarity as
    manifested by the apical, polar localization of PIN2. We show that the apical
    domain is defined in a cell-intrinsic manner and that re-establishment of PIN2
    localization to this domain requires de novo protein secretion and endocytosis,
    but not basal-to-apical transcytosis. Furthermore, we identify a PINOID-related
    kinase WAG1, which phosphorylates PIN2 in vitro6 and is transcriptionally upregulated
    specifically in dividing cells, as a crucial regulator of post-cytokinetic PIN2
    polarity re-establishment.
article_processing_charge: No
author:
- first_name: Matous
  full_name: Glanc, Matous
  id: 1AE1EA24-02D0-11E9-9BAA-DAF4881429F2
  last_name: Glanc
  orcid: 0000-0003-0619-7783
- first_name: Matyas
  full_name: Fendrych, Matyas
  id: 43905548-F248-11E8-B48F-1D18A9856A87
  last_name: Fendrych
  orcid: 0000-0002-9767-8699
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Glanc M, Fendrych M, Friml J. Mechanistic framework for cell-intrinsic re-establishment
    of PIN2 polarity after cell division. <i>Nature Plants</i>. 2018;4(12):1082-1088.
    doi:<a href="https://doi.org/10.1038/s41477-018-0318-3">10.1038/s41477-018-0318-3</a>
  apa: Glanc, M., Fendrych, M., &#38; Friml, J. (2018). Mechanistic framework for
    cell-intrinsic re-establishment of PIN2 polarity after cell division. <i>Nature
    Plants</i>. Nature Research. <a href="https://doi.org/10.1038/s41477-018-0318-3">https://doi.org/10.1038/s41477-018-0318-3</a>
  chicago: Glanc, Matous, Matyas Fendrych, and Jiří Friml. “Mechanistic Framework
    for Cell-Intrinsic Re-Establishment of PIN2 Polarity after Cell Division.” <i>Nature
    Plants</i>. Nature Research, 2018. <a href="https://doi.org/10.1038/s41477-018-0318-3">https://doi.org/10.1038/s41477-018-0318-3</a>.
  ieee: M. Glanc, M. Fendrych, and J. Friml, “Mechanistic framework for cell-intrinsic
    re-establishment of PIN2 polarity after cell division,” <i>Nature Plants</i>,
    vol. 4, no. 12. Nature Research, pp. 1082–1088, 2018.
  ista: Glanc M, Fendrych M, Friml J. 2018. Mechanistic framework for cell-intrinsic
    re-establishment of PIN2 polarity after cell division. Nature Plants. 4(12), 1082–1088.
  mla: Glanc, Matous, et al. “Mechanistic Framework for Cell-Intrinsic Re-Establishment
    of PIN2 Polarity after Cell Division.” <i>Nature Plants</i>, vol. 4, no. 12, Nature
    Research, 2018, pp. 1082–88, doi:<a href="https://doi.org/10.1038/s41477-018-0318-3">10.1038/s41477-018-0318-3</a>.
  short: M. Glanc, M. Fendrych, J. Friml, Nature Plants 4 (2018) 1082–1088.
date_created: 2018-12-16T22:59:18Z
date_published: 2018-12-03T00:00:00Z
date_updated: 2025-04-14T07:45:02Z
day: '03'
department:
- _id: JiFr
doi: 10.1038/s41477-018-0318-3
ec_funded: 1
external_id:
  isi:
  - '000454576600017'
  pmid:
  - '30518833'
intvolume: '         4'
isi: 1
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pubmed/30518833
month: '12'
oa: 1
oa_version: Submitted Version
page: 1082-1088
pmid: 1
project:
- _id: 261099A6-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '742985'
  name: Tracing Evolution of Auxin Transport and Polarity in Plants
publication: Nature Plants
publication_identifier:
  issn:
  - 2055-0278
publication_status: published
publisher: Nature Research
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mechanistic framework for cell-intrinsic re-establishment of PIN2 polarity
  after cell division
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 4
year: '2018'
...
---
_id: '5676'
abstract:
- lang: eng
  text: 'In epithelial tissues, cells tightly connect to each other through cell–cell
    junctions, but they also present the remarkable capacity of reorganizing themselves
    without compromising tissue integrity. Upon injury, simple epithelia efficiently
    resolve small lesions through the action of actin cytoskeleton contractile structures
    at the wound edge and cellular rearrangements. However, the underlying mechanisms
    and how they cooperate are still poorly understood. In this study, we combine
    live imaging and theoretical modeling to reveal a novel and indispensable role
    for occluding junctions (OJs) in this process. We demonstrate that OJ loss of
    function leads to defects in wound-closure dynamics: instead of contracting, wounds
    dramatically increase their area. OJ mutants exhibit phenotypes in cell shape,
    cellular rearrangements, and mechanical properties as well as in actin cytoskeleton
    dynamics at the wound edge. We propose that OJs are essential for wound closure
    by impacting on epithelial mechanics at the tissue level, which in turn is crucial
    for correct regulation of the cellular events occurring at the wound edge.'
article_processing_charge: No
author:
- first_name: Lara
  full_name: Carvalho, Lara
  last_name: Carvalho
- first_name: Pedro
  full_name: Patricio, Pedro
  last_name: Patricio
- first_name: Susana
  full_name: Ponte, Susana
  last_name: Ponte
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
- first_name: Luis
  full_name: Almeida, Luis
  last_name: Almeida
- first_name: André S.
  full_name: Nunes, André S.
  last_name: Nunes
- first_name: Nuno A.M.
  full_name: Araújo, Nuno A.M.
  last_name: Araújo
- first_name: Antonio
  full_name: Jacinto, Antonio
  last_name: Jacinto
citation:
  ama: Carvalho L, Patricio P, Ponte S, et al. Occluding junctions as novel regulators
    of tissue mechanics during wound repair. <i>Journal of Cell Biology</i>. 2018;217(12):4267-4283.
    doi:<a href="https://doi.org/10.1083/jcb.201804048">10.1083/jcb.201804048</a>
  apa: Carvalho, L., Patricio, P., Ponte, S., Heisenberg, C.-P. J., Almeida, L., Nunes,
    A. S., … Jacinto, A. (2018). Occluding junctions as novel regulators of tissue
    mechanics during wound repair. <i>Journal of Cell Biology</i>. Rockefeller University
    Press. <a href="https://doi.org/10.1083/jcb.201804048">https://doi.org/10.1083/jcb.201804048</a>
  chicago: Carvalho, Lara, Pedro Patricio, Susana Ponte, Carl-Philipp J Heisenberg,
    Luis Almeida, André S. Nunes, Nuno A.M. Araújo, and Antonio Jacinto. “Occluding
    Junctions as Novel Regulators of Tissue Mechanics during Wound Repair.” <i>Journal
    of Cell Biology</i>. Rockefeller University Press, 2018. <a href="https://doi.org/10.1083/jcb.201804048">https://doi.org/10.1083/jcb.201804048</a>.
  ieee: L. Carvalho <i>et al.</i>, “Occluding junctions as novel regulators of tissue
    mechanics during wound repair,” <i>Journal of Cell Biology</i>, vol. 217, no.
    12. Rockefeller University Press, pp. 4267–4283, 2018.
  ista: Carvalho L, Patricio P, Ponte S, Heisenberg C-PJ, Almeida L, Nunes AS, Araújo
    NAM, Jacinto A. 2018. Occluding junctions as novel regulators of tissue mechanics
    during wound repair. Journal of Cell Biology. 217(12), 4267–4283.
  mla: Carvalho, Lara, et al. “Occluding Junctions as Novel Regulators of Tissue Mechanics
    during Wound Repair.” <i>Journal of Cell Biology</i>, vol. 217, no. 12, Rockefeller
    University Press, 2018, pp. 4267–83, doi:<a href="https://doi.org/10.1083/jcb.201804048">10.1083/jcb.201804048</a>.
  short: L. Carvalho, P. Patricio, S. Ponte, C.-P.J. Heisenberg, L. Almeida, A.S.
    Nunes, N.A.M. Araújo, A. Jacinto, Journal of Cell Biology 217 (2018) 4267–4283.
date_created: 2018-12-16T22:59:19Z
date_published: 2018-12-01T00:00:00Z
date_updated: 2025-07-10T11:52:53Z
day: '01'
department:
- _id: CaHe
doi: 10.1083/jcb.201804048
ec_funded: 1
external_id:
  isi:
  - '000451960800018'
  pmid:
  - '30228162 '
intvolume: '       217'
isi: 1
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pubmed/30228162
month: '12'
oa: 1
oa_version: Submitted Version
page: 4267-4283
pmid: 1
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication: Journal of Cell Biology
publication_identifier:
  issn:
  - 0021-9525
publication_status: published
publisher: Rockefeller University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Occluding junctions as novel regulators of tissue mechanics during wound repair
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 217
year: '2018'
...
---
_id: '5677'
abstract:
- lang: eng
  text: 'Recently, contract-based design has been proposed as an “orthogonal” approach
    that complements system design methodologies proposed so far to cope with the
    complexity of system design. Contract-based design provides a rigorous scaffolding
    for verification, analysis, abstraction/refinement, and even synthesis. A number
    of results have been obtained in this domain but a unified treatment of the topic
    that can help put contract-based design in perspective was missing. This monograph
    intends to provide such a treatment where contracts are precisely defined and
    characterized so that they can be used in design methodologies with no ambiguity.
    In particular, this monograph identifies the essence of complex system design
    using contracts through a mathematical “meta-theory”, where all the properties
    of the methodology are derived from a very abstract and generic notion of contract.
    We show that the meta-theory provides deep and illuminating links with existing
    contract and interface theories, as well as guidelines for designing new theories.
    Our study encompasses contracts for both software and systems, with emphasis on
    the latter. We illustrate the use of contracts with two examples: requirement
    engineering for a parking garage management, and the development of contracts
    for timing and scheduling in the context of the Autosar methodology in use in
    the automotive sector.'
article_processing_charge: No
article_type: original
author:
- first_name: Albert
  full_name: Benveniste, Albert
  last_name: Benveniste
- first_name: Dejan
  full_name: Nickovic, Dejan
  last_name: Nickovic
- first_name: Benoît
  full_name: Caillaud, Benoît
  last_name: Caillaud
- first_name: Roberto
  full_name: Passerone, Roberto
  last_name: Passerone
- first_name: Jean Baptiste
  full_name: Raclet, Jean Baptiste
  last_name: Raclet
- first_name: Philipp
  full_name: Reinkemeier, Philipp
  last_name: Reinkemeier
- first_name: Alberto
  full_name: Sangiovanni-Vincentelli, Alberto
  last_name: Sangiovanni-Vincentelli
- first_name: Werner
  full_name: Damm, Werner
  last_name: Damm
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Kim G.
  full_name: Larsen, Kim G.
  last_name: Larsen
citation:
  ama: Benveniste A, Nickovic D, Caillaud B, et al. Contracts for system design. <i>Foundations
    and Trends in Electronic Design Automation</i>. 2018;12(2-3):124-400. doi:<a href="https://doi.org/10.1561/1000000053">10.1561/1000000053</a>
  apa: Benveniste, A., Nickovic, D., Caillaud, B., Passerone, R., Raclet, J. B., Reinkemeier,
    P., … Larsen, K. G. (2018). Contracts for system design. <i>Foundations and Trends
    in Electronic Design Automation</i>. Now Publishers. <a href="https://doi.org/10.1561/1000000053">https://doi.org/10.1561/1000000053</a>
  chicago: Benveniste, Albert, Dejan Nickovic, Benoît Caillaud, Roberto Passerone,
    Jean Baptiste Raclet, Philipp Reinkemeier, Alberto Sangiovanni-Vincentelli, Werner
    Damm, Thomas A Henzinger, and Kim G. Larsen. “Contracts for System Design.” <i>Foundations
    and Trends in Electronic Design Automation</i>. Now Publishers, 2018. <a href="https://doi.org/10.1561/1000000053">https://doi.org/10.1561/1000000053</a>.
  ieee: A. Benveniste <i>et al.</i>, “Contracts for system design,” <i>Foundations
    and Trends in Electronic Design Automation</i>, vol. 12, no. 2–3. Now Publishers,
    pp. 124–400, 2018.
  ista: Benveniste A, Nickovic D, Caillaud B, Passerone R, Raclet JB, Reinkemeier
    P, Sangiovanni-Vincentelli A, Damm W, Henzinger TA, Larsen KG. 2018. Contracts
    for system design. Foundations and Trends in Electronic Design Automation. 12(2–3),
    124–400.
  mla: Benveniste, Albert, et al. “Contracts for System Design.” <i>Foundations and
    Trends in Electronic Design Automation</i>, vol. 12, no. 2–3, Now Publishers,
    2018, pp. 124–400, doi:<a href="https://doi.org/10.1561/1000000053">10.1561/1000000053</a>.
  short: A. Benveniste, D. Nickovic, B. Caillaud, R. Passerone, J.B. Raclet, P. Reinkemeier,
    A. Sangiovanni-Vincentelli, W. Damm, T.A. Henzinger, K.G. Larsen, Foundations
    and Trends in Electronic Design Automation 12 (2018) 124–400.
date_created: 2018-12-16T22:59:19Z
date_published: 2018-05-01T00:00:00Z
date_updated: 2023-10-17T11:53:09Z
day: '01'
department:
- _id: ToHe
doi: 10.1561/1000000053
intvolume: '        12'
issue: 2-3
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://hal.inria.fr/hal-00757488/
month: '05'
oa: 1
oa_version: Submitted Version
page: 124-400
publication: Foundations and Trends in Electronic Design Automation
publication_identifier:
  issn:
  - 1551-3939
publication_status: published
publisher: Now Publishers
quality_controlled: '1'
scopus_import: '1'
status: public
title: Contracts for system design
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2018'
...
---
_id: '5686'
article_processing_charge: No
author:
- first_name: Patrick
  full_name: Danowski, Patrick
  id: 2EBD1598-F248-11E8-B48F-1D18A9856A87
  last_name: Danowski
  orcid: 0000-0002-6026-4409
citation:
  ama: Danowski P. <i>An Austrian Proposal for the Classification of Open Access Tuples
    (COAT) - Distinguish Different Open Access Types beyond Colors</i>.; 2018. doi:<a
    href="https://doi.org/10.5281/zenodo.1244154">10.5281/zenodo.1244154</a>
  apa: Danowski, P. (2018). <i>An Austrian proposal for the Classification of Open
    Access Tuples (COAT) - Distinguish different Open Access types beyond colors</i>.
    <a href="https://doi.org/10.5281/zenodo.1244154">https://doi.org/10.5281/zenodo.1244154</a>
  chicago: Danowski, Patrick. <i>An Austrian Proposal for the Classification of Open
    Access Tuples (COAT) - Distinguish Different Open Access Types beyond Colors</i>,
    2018. <a href="https://doi.org/10.5281/zenodo.1244154">https://doi.org/10.5281/zenodo.1244154</a>.
  ieee: P. Danowski, <i>An Austrian proposal for the Classification of Open Access
    Tuples (COAT) - Distinguish different Open Access types beyond colors</i>. 2018.
  ista: Danowski P. 2018. An Austrian proposal for the Classification of Open Access
    Tuples (COAT) - Distinguish different Open Access types beyond colors, 5p.
  mla: Danowski, Patrick. <i>An Austrian Proposal for the Classification of Open Access
    Tuples (COAT) - Distinguish Different Open Access Types beyond Colors</i>. 2018,
    doi:<a href="https://doi.org/10.5281/zenodo.1244154">10.5281/zenodo.1244154</a>.
  short: P. Danowski, An Austrian Proposal for the Classification of Open Access Tuples
    (COAT) - Distinguish Different Open Access Types beyond Colors, 2018.
date_created: 2018-12-17T10:28:26Z
date_published: 2018-05-09T00:00:00Z
date_updated: 2024-10-09T20:58:54Z
day: '09'
ddc:
- '020'
department:
- _id: E-Lib
doi: 10.5281/zenodo.1244154
file:
- access_level: open_access
  checksum: 6cb95f8772491d155ce77c6160655fff
  content_type: application/pdf
  creator: dernst
  date_created: 2019-01-22T09:06:51Z
  date_updated: 2020-07-14T12:47:10Z
  file_id: '5872'
  file_name: 2018_WorkingPaper_Danowski.pdf
  file_size: 202798
  relation: main_file
file_date_updated: 2020-07-14T12:47:10Z
has_accepted_license: '1'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: '5'
publication_status: published
related_material:
  record:
  - id: '6657'
    relation: later_version
    status: public
scopus_import: 1
status: public
title: An Austrian proposal for the Classification of Open Access Tuples (COAT) -
  Distinguish different Open Access types beyond colors
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: working_paper
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
year: '2018'
...
---
_id: '5757'
abstract:
- lang: eng
  text: "File S1. Variant Calling Format file of the ingroup: 197 haploid sequences
    of D. melanogaster from Zambia (Africa) aligned to the D. melanogaster 5.57 reference
    genome.\r\n\r\nFile S2. Variant Calling Format file of the outgroup: 1 haploid
    sequence of D. simulans aligned to the D. melanogaster 5.57 reference genome.\r\n\r\nFile
    S3. Annotations of each transcript in coding regions with SNPeff: Ps (# of synonymous
    polymorphic sites); Pn (# of non-synonymous polymorphic sites); Ds (# of synonymous
    divergent sites); Dn (# of non-synonymous divergent sites); DoS; ⍺ MK . All variants
    were included.\r\n\r\nFile S4. Annotations of each transcript in non-coding regions
    with SNPeff: Ps (# of synonymous polymorphic sites); Pu (# of UTR polymorphic
    sites); Ds (# of synonymous divergent sites); Du (# of UTR divergent sites); DoS;
    ⍺ MK . All variants were included.\r\n\r\nFile S5. Annotations of each transcript
    in coding regions with SNPGenie: Ps (# of synonymous polymorphic sites); πs (synonymous
    diversity); Ss_p (total # of synonymous sites in the polymorphism data); Pn (#
    of non-synonymous polymorphic sites); πn (non-synonymous diversity); Sn_p (total
    # of non-synonymous sites in the polymorphism data); Ds (# of synonymous divergent
    sites); ks (synonymous evolutionary rate); Ss_d (total # of synonymous sites in
    the divergence data); Dn (# of non-synonymous divergent sites); kn (non-synonymous
    evolutionary rate); Sn_d (total # of non-\r\nsynonymous sites in the divergence
    data); DoS; ⍺ MK . All variants were included.\r\n\r\nFile S6. Gene expression
    values (RPKM summed over all transcripts) for each sample. Values were quantile-normalized
    across all samples.\r\n\r\nFile S7. Final dataset with all covariates, ⍺ MK ,
    ωA MK and DoS for coding sites, excluding variants below 5% frequency.\r\n\r\nFile
    S8. Final dataset with all covariates, ⍺ MK , ωA MK and DoS for non-coding sites,
    excluding variants below 5%\r\nfrequency.\r\n\r\nFile S9. Final dataset with all
    covariates, ⍺ EWK , ωA EWK and deleterious SFS for coding sites obtained with
    the Eyre-Walker and Keightley method on binned data and using all variants."
article_processing_charge: No
author:
- first_name: Christelle
  full_name: Fraisse, Christelle
  id: 32DF5794-F248-11E8-B48F-1D18A9856A87
  last_name: Fraisse
  orcid: 0000-0001-8441-5075
citation:
  ama: Fraisse C. Supplementary Files for “Pleiotropy modulates the efficacy of selection
    in Drosophila melanogaster.” 2018. doi:<a href="https://doi.org/10.15479/at:ista:/5757">10.15479/at:ista:/5757</a>
  apa: Fraisse, C. (2018). Supplementary Files for “Pleiotropy modulates the efficacy
    of selection in Drosophila melanogaster.” Institute of Science and Technology
    Austria. <a href="https://doi.org/10.15479/at:ista:/5757">https://doi.org/10.15479/at:ista:/5757</a>
  chicago: Fraisse, Christelle. “Supplementary Files for ‘Pleiotropy Modulates the
    Efficacy of Selection in Drosophila Melanogaster.’” Institute of Science and Technology
    Austria, 2018. <a href="https://doi.org/10.15479/at:ista:/5757">https://doi.org/10.15479/at:ista:/5757</a>.
  ieee: C. Fraisse, “Supplementary Files for ‘Pleiotropy modulates the efficacy of
    selection in Drosophila melanogaster.’” Institute of Science and Technology Austria,
    2018.
  ista: Fraisse C. 2018. Supplementary Files for ‘Pleiotropy modulates the efficacy
    of selection in Drosophila melanogaster’, Institute of Science and Technology
    Austria, <a href="https://doi.org/10.15479/at:ista:/5757">10.15479/at:ista:/5757</a>.
  mla: Fraisse, Christelle. <i>Supplementary Files for “Pleiotropy Modulates the Efficacy
    of Selection in Drosophila Melanogaster.”</i> Institute of Science and Technology
    Austria, 2018, doi:<a href="https://doi.org/10.15479/at:ista:/5757">10.15479/at:ista:/5757</a>.
  short: C. Fraisse, (2018).
contributor:
- first_name: Christelle
  id: 32DF5794-F248-11E8-B48F-1D18A9856A87
  last_name: Fraisse
- first_name: Gemma
  id: 33AB266C-F248-11E8-B48F-1D18A9856A87
  last_name: Puixeu Sala
- first_name: Beatriz
  id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
  last_name: Vicoso
  orcid: 0000-0002-4579-8306
date_created: 2018-12-19T14:22:35Z
date_published: 2018-12-19T00:00:00Z
date_updated: 2025-04-15T08:18:38Z
day: '19'
ddc:
- '576'
department:
- _id: BeVi
- _id: NiBa
doi: 10.15479/at:ista:/5757
ec_funded: 1
file:
- access_level: open_access
  checksum: aed7ee9ca3f4dc07d8a66945f68e13cd
  content_type: application/zip
  creator: cfraisse
  date_created: 2018-12-19T14:19:52Z
  date_updated: 2020-07-14T12:47:11Z
  file_id: '5758'
  file_name: FileS1.zip
  file_size: 369837892
  relation: main_file
- access_level: open_access
  checksum: 3592e467b4d8206650860b612d6e12f3
  content_type: application/zip
  creator: cfraisse
  date_created: 2018-12-19T14:19:49Z
  date_updated: 2020-07-14T12:47:11Z
  file_id: '5759'
  file_name: FileS2.zip
  file_size: 84856909
  relation: main_file
- access_level: open_access
  checksum: c37ac5d5437c457338afc128c1240655
  content_type: text/plain
  creator: cfraisse
  date_created: 2018-12-19T14:19:49Z
  date_updated: 2020-07-14T12:47:11Z
  file_id: '5760'
  file_name: FileS3.txt
  file_size: 881133
  relation: main_file
- access_level: open_access
  checksum: 943dfd14da61817441e33e3e3cb8cdb9
  content_type: text/plain
  creator: cfraisse
  date_created: 2018-12-19T14:19:49Z
  date_updated: 2020-07-14T12:47:11Z
  file_id: '5761'
  file_name: FileS4.txt
  file_size: 883742
  relation: main_file
- access_level: open_access
  checksum: 1c669b6c4690ec1bbca3e2da9f566d17
  content_type: text/plain
  creator: cfraisse
  date_created: 2018-12-19T14:19:49Z
  date_updated: 2020-07-14T12:47:11Z
  file_id: '5762'
  file_name: FileS5.txt
  file_size: 2495437
  relation: main_file
- access_level: open_access
  checksum: f40f661b987ca6fb6b47f650cbbb04e6
  content_type: text/plain
  creator: cfraisse
  date_created: 2018-12-19T14:19:50Z
  date_updated: 2020-07-14T12:47:11Z
  file_id: '5763'
  file_name: FileS6.txt
  file_size: 15913457
  relation: main_file
- access_level: open_access
  checksum: 25f41e5b8a075669c6c88d4c6713bf6f
  content_type: text/plain
  creator: cfraisse
  date_created: 2018-12-19T14:19:50Z
  date_updated: 2020-07-14T12:47:11Z
  file_id: '5764'
  file_name: FileS7.txt
  file_size: 2584120
  relation: main_file
- access_level: open_access
  checksum: f6c0bd3e63e14ddf5445bd69b43a9152
  content_type: text/plain
  creator: cfraisse
  date_created: 2018-12-19T14:19:50Z
  date_updated: 2020-07-14T12:47:11Z
  file_id: '5765'
  file_name: FileS8.txt
  file_size: 2446059
  relation: main_file
- access_level: open_access
  checksum: 0fe7a58a030b11bf3b9c8ff7a7addcae
  content_type: text/plain
  creator: cfraisse
  date_created: 2018-12-19T14:19:50Z
  date_updated: 2020-07-14T12:47:11Z
  file_id: '5766'
  file_name: FileS9.txt
  file_size: 100737
  relation: main_file
file_date_updated: 2020-07-14T12:47:11Z
has_accepted_license: '1'
keyword:
- (mal)adaptation
- pleiotropy
- selective constraint
- evo-devo
- gene expression
- Drosophila melanogaster
month: '12'
oa: 1
oa_version: Published Version
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '6089'
    relation: research_paper
    status: public
status: public
title: Supplementary Files for "Pleiotropy modulates the efficacy of selection in
  Drosophila melanogaster"
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2018'
...
---
_id: '5767'
abstract:
- lang: eng
  text: 'Cuprate superconductors have long been thought of as having strong electronic
    correlations but negligible spin-orbit coupling. Using spin- and angle-resolved
    photoemission spectroscopy, we discovered that one of the most studied cuprate
    superconductors, Bi2212, has a nontrivial spin texture with a spin-momentum locking
    that circles the Brillouin zone center and a spin-layer locking that allows states
    of opposite spin to be localized in different parts of the unit cell. Our findings
    pose challenges for the vast majority of models of cuprates, such as the Hubbard
    model and its variants, where spin-orbit interaction has been mostly neglected,
    and open the intriguing question of how the high-temperature superconducting state
    emerges in the presence of this nontrivial spin texture. '
acknowledgement: ' M.S. was supported by the Gordon and Betty Moore Foundation s EPiQS
  Initiative through grant GBMF4307'
article_processing_charge: No
article_type: original
author:
- first_name: Kenneth
  full_name: Gotlieb, Kenneth
  last_name: Gotlieb
- first_name: Chiu-Yun
  full_name: Lin, Chiu-Yun
  last_name: Lin
- first_name: Maksym
  full_name: Serbyn, Maksym
  id: 47809E7E-F248-11E8-B48F-1D18A9856A87
  last_name: Serbyn
  orcid: 0000-0002-2399-5827
- first_name: Wentao
  full_name: Zhang, Wentao
  last_name: Zhang
- first_name: Christopher L.
  full_name: Smallwood, Christopher L.
  last_name: Smallwood
- first_name: Christopher
  full_name: Jozwiak, Christopher
  last_name: Jozwiak
- first_name: Hiroshi
  full_name: Eisaki, Hiroshi
  last_name: Eisaki
- first_name: Zahid
  full_name: Hussain, Zahid
  last_name: Hussain
- first_name: Ashvin
  full_name: Vishwanath, Ashvin
  last_name: Vishwanath
- first_name: Alessandra
  full_name: Lanzara, Alessandra
  last_name: Lanzara
citation:
  ama: Gotlieb K, Lin C-Y, Serbyn M, et al. Revealing hidden spin-momentum locking
    in a high-temperature cuprate superconductor. <i>Science</i>. 2018;362(6420):1271-1275.
    doi:<a href="https://doi.org/10.1126/science.aao0980">10.1126/science.aao0980</a>
  apa: Gotlieb, K., Lin, C.-Y., Serbyn, M., Zhang, W., Smallwood, C. L., Jozwiak,
    C., … Lanzara, A. (2018). Revealing hidden spin-momentum locking in a high-temperature
    cuprate superconductor. <i>Science</i>. American Association for the Advancement
    of Science. <a href="https://doi.org/10.1126/science.aao0980">https://doi.org/10.1126/science.aao0980</a>
  chicago: Gotlieb, Kenneth, Chiu-Yun Lin, Maksym Serbyn, Wentao Zhang, Christopher
    L. Smallwood, Christopher Jozwiak, Hiroshi Eisaki, Zahid Hussain, Ashvin Vishwanath,
    and Alessandra Lanzara. “Revealing Hidden Spin-Momentum Locking in a High-Temperature
    Cuprate Superconductor.” <i>Science</i>. American Association for the Advancement
    of Science, 2018. <a href="https://doi.org/10.1126/science.aao0980">https://doi.org/10.1126/science.aao0980</a>.
  ieee: K. Gotlieb <i>et al.</i>, “Revealing hidden spin-momentum locking in a high-temperature
    cuprate superconductor,” <i>Science</i>, vol. 362, no. 6420. American Association
    for the Advancement of Science, pp. 1271–1275, 2018.
  ista: Gotlieb K, Lin C-Y, Serbyn M, Zhang W, Smallwood CL, Jozwiak C, Eisaki H,
    Hussain Z, Vishwanath A, Lanzara A. 2018. Revealing hidden spin-momentum locking
    in a high-temperature cuprate superconductor. Science. 362(6420), 1271–1275.
  mla: Gotlieb, Kenneth, et al. “Revealing Hidden Spin-Momentum Locking in a High-Temperature
    Cuprate Superconductor.” <i>Science</i>, vol. 362, no. 6420, American Association
    for the Advancement of Science, 2018, pp. 1271–75, doi:<a href="https://doi.org/10.1126/science.aao0980">10.1126/science.aao0980</a>.
  short: K. Gotlieb, C.-Y. Lin, M. Serbyn, W. Zhang, C.L. Smallwood, C. Jozwiak, H.
    Eisaki, Z. Hussain, A. Vishwanath, A. Lanzara, Science 362 (2018) 1271–1275.
date_created: 2018-12-19T14:53:50Z
date_published: 2018-12-14T00:00:00Z
date_updated: 2023-09-18T08:11:56Z
day: '14'
department:
- _id: MaSe
doi: 10.1126/science.aao0980
external_id:
  isi:
  - '000452994400048'
intvolume: '       362'
isi: 1
issue: '6420'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1126/science.aao0980
month: '12'
oa: 1
oa_version: Published Version
page: 1271-1275
publication: Science
publication_identifier:
  eissn:
  - 1095-9203
  issn:
  - 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Revealing hidden spin-momentum locking in a high-temperature cuprate superconductor
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 362
year: '2018'
...
---
_id: '5770'
abstract:
- lang: eng
  text: Retroviruses assemble and bud from infected cells in an immature form and
    require proteolytic maturation for infectivity. The CA (capsid) domains of the
    Gag polyproteins assemble a protein lattice as a truncated sphere in the immature
    virion. Proteolytic cleavage of Gag induces dramatic structural rearrangements;
    a subset of cleaved CA subsequently assembles into the mature core, whose architecture
    varies among retroviruses. Murine leukemia virus (MLV) is the prototypical γ-retrovirus
    and serves as the basis of retroviral vectors, but the structure of the MLV CA
    layer is unknown. Here we have combined X-ray crystallography with cryoelectron
    tomography to determine the structures of immature and mature MLV CA layers within
    authentic viral particles. This reveals the structural changes associated with
    maturation, and, by comparison with HIV-1, uncovers conserved and variable features.
    In contrast to HIV-1, most MLV CA is used for assembly of the mature core, which
    adopts variable, multilayered morphologies and does not form a closed structure.
    Unlike in HIV-1, there is similarity between protein–protein interfaces in the
    immature MLV CA layer and those in the mature CA layer, and structural maturation
    of MLV could be achieved through domain rotations that largely maintain hexameric
    interactions. Nevertheless, the dramatic architectural change on maturation indicates
    that extensive disassembly and reassembly are required for mature core growth.
    The core morphology suggests that wrapping of the genome in CA sheets may be sufficient
    to protect the MLV ribonucleoprotein during cell entry.
article_processing_charge: No
author:
- first_name: Kun
  full_name: Qu, Kun
  last_name: Qu
- first_name: Bärbel
  full_name: Glass, Bärbel
  last_name: Glass
- first_name: Michal
  full_name: Doležal, Michal
  last_name: Doležal
- first_name: Florian
  full_name: Schur, Florian
  id: 48AD8942-F248-11E8-B48F-1D18A9856A87
  last_name: Schur
  orcid: 0000-0003-4790-8078
- first_name: Brice
  full_name: Murciano, Brice
  last_name: Murciano
- first_name: Alan
  full_name: Rein, Alan
  last_name: Rein
- first_name: Michaela
  full_name: Rumlová, Michaela
  last_name: Rumlová
- first_name: Tomáš
  full_name: Ruml, Tomáš
  last_name: Ruml
- first_name: Hans-Georg
  full_name: Kräusslich, Hans-Georg
  last_name: Kräusslich
- first_name: John A. G.
  full_name: Briggs, John A. G.
  last_name: Briggs
citation:
  ama: Qu K, Glass B, Doležal M, et al. Structure and architecture of immature and
    mature murine leukemia virus capsids. <i>Proceedings of the National Academy of
    Sciences of the United States of America</i>. 2018;115(50):E11751-E11760. doi:<a
    href="https://doi.org/10.1073/pnas.1811580115">10.1073/pnas.1811580115</a>
  apa: Qu, K., Glass, B., Doležal, M., Schur, F. K., Murciano, B., Rein, A., … Briggs,
    J. A. G. (2018). Structure and architecture of immature and mature murine leukemia
    virus capsids. <i>Proceedings of the National Academy of Sciences of the United
    States of America</i>. National Academy of Sciences. <a href="https://doi.org/10.1073/pnas.1811580115">https://doi.org/10.1073/pnas.1811580115</a>
  chicago: Qu, Kun, Bärbel Glass, Michal Doležal, Florian KM Schur, Brice Murciano,
    Alan Rein, Michaela Rumlová, Tomáš Ruml, Hans-Georg Kräusslich, and John A. G.
    Briggs. “Structure and Architecture of Immature and Mature Murine Leukemia Virus
    Capsids.” <i>Proceedings of the National Academy of Sciences of the United States
    of America</i>. National Academy of Sciences, 2018. <a href="https://doi.org/10.1073/pnas.1811580115">https://doi.org/10.1073/pnas.1811580115</a>.
  ieee: K. Qu <i>et al.</i>, “Structure and architecture of immature and mature murine
    leukemia virus capsids,” <i>Proceedings of the National Academy of Sciences of
    the United States of America</i>, vol. 115, no. 50. National Academy of Sciences,
    pp. E11751–E11760, 2018.
  ista: Qu K, Glass B, Doležal M, Schur FK, Murciano B, Rein A, Rumlová M, Ruml T,
    Kräusslich H-G, Briggs JAG. 2018. Structure and architecture of immature and mature
    murine leukemia virus capsids. Proceedings of the National Academy of Sciences
    of the United States of America. 115(50), E11751–E11760.
  mla: Qu, Kun, et al. “Structure and Architecture of Immature and Mature Murine Leukemia
    Virus Capsids.” <i>Proceedings of the National Academy of Sciences of the United
    States of America</i>, vol. 115, no. 50, National Academy of Sciences, 2018, pp.
    E11751–60, doi:<a href="https://doi.org/10.1073/pnas.1811580115">10.1073/pnas.1811580115</a>.
  short: K. Qu, B. Glass, M. Doležal, F.K. Schur, B. Murciano, A. Rein, M. Rumlová,
    T. Ruml, H.-G. Kräusslich, J.A.G. Briggs, Proceedings of the National Academy
    of Sciences of the United States of America 115 (2018) E11751–E11760.
date_created: 2018-12-20T21:09:37Z
date_published: 2018-12-11T00:00:00Z
date_updated: 2025-06-03T11:56:09Z
day: '11'
department:
- _id: FlSc
doi: 10.1073/pnas.1811580115
external_id:
  isi:
  - '000452866000022'
  pmid:
  - '30478053'
intvolume: '       115'
isi: 1
issue: '50'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pubmed/30478053
month: '12'
oa: 1
oa_version: Submitted Version
page: E11751-E11760
pmid: 1
publication: Proceedings of the National Academy of Sciences of the United States
  of America
publication_identifier:
  issn:
  - 0027-8424
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Structure and architecture of immature and mature murine leukemia virus capsids
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 115
year: '2018'
...
---
_id: '5780'
abstract:
- lang: eng
  text: Bioluminescence is found across the entire tree of life, conferring a spectacular
    set of visually oriented functions from attracting mates to scaring off predators.
    Half a dozen different luciferins, molecules that emit light when enzymatically
    oxidized, are known. However, just one biochemical pathway for luciferin biosynthesis
    has been described in full, which is found only in bacteria. Here, we report identification
    of the fungal luciferase and three other key enzymes that together form the biosynthetic
    cycle of the fungal luciferin from caffeic acid, a simple and widespread metabolite.
    Introduction of the identified genes into the genome of the yeast Pichia pastoris
    along with caffeic acid biosynthesis genes resulted in a strain that is autoluminescent
    in standard media. We analyzed evolution of the enzymes of the luciferin biosynthesis
    cycle and found that fungal bioluminescence emerged through a series of events
    that included two independent gene duplications. The retention of the duplicated
    enzymes of the luciferin pathway in nonluminescent fungi shows that the gene duplication
    was followed by functional sequence divergence of enzymes of at least one gene
    in the biosynthetic pathway and suggests that the evolution of fungal bioluminescence
    proceeded through several closely related stepping stone nonluminescent biochemical
    reactions with adaptive roles. The availability of a complete eukaryotic luciferin
    biosynthesis pathway provides several applications in biomedicine and bioengineering.
article_processing_charge: No
author:
- first_name: Alexey A.
  full_name: Kotlobay, Alexey A.
  last_name: Kotlobay
- first_name: Karen
  full_name: Sarkisyan, Karen
  id: 39A7BF80-F248-11E8-B48F-1D18A9856A87
  last_name: Sarkisyan
  orcid: 0000-0002-5375-6341
- first_name: Yuliana A.
  full_name: Mokrushina, Yuliana A.
  last_name: Mokrushina
- first_name: Marina
  full_name: Marcet-Houben, Marina
  last_name: Marcet-Houben
- first_name: Ekaterina O.
  full_name: Serebrovskaya, Ekaterina O.
  last_name: Serebrovskaya
- first_name: Nadezhda M.
  full_name: Markina, Nadezhda M.
  last_name: Markina
- first_name: Louisa
  full_name: Gonzalez Somermeyer, Louisa
  id: 4720D23C-F248-11E8-B48F-1D18A9856A87
  last_name: Gonzalez Somermeyer
  orcid: 0000-0001-9139-5383
- first_name: Andrey Y.
  full_name: Gorokhovatsky, Andrey Y.
  last_name: Gorokhovatsky
- first_name: Andrey
  full_name: Vvedensky, Andrey
  last_name: Vvedensky
- first_name: Konstantin V.
  full_name: Purtov, Konstantin V.
  last_name: Purtov
- first_name: Valentin N.
  full_name: Petushkov, Valentin N.
  last_name: Petushkov
- first_name: Natalja S.
  full_name: Rodionova, Natalja S.
  last_name: Rodionova
- first_name: Tatiana V.
  full_name: Chepurnyh, Tatiana V.
  last_name: Chepurnyh
- first_name: Liliia
  full_name: Fakhranurova, Liliia
  last_name: Fakhranurova
- first_name: Elena B.
  full_name: Guglya, Elena B.
  last_name: Guglya
- first_name: Rustam
  full_name: Ziganshin, Rustam
  last_name: Ziganshin
- first_name: Aleksandra S.
  full_name: Tsarkova, Aleksandra S.
  last_name: Tsarkova
- first_name: Zinaida M.
  full_name: Kaskova, Zinaida M.
  last_name: Kaskova
- first_name: Victoria
  full_name: Shender, Victoria
  last_name: Shender
- first_name: Maxim
  full_name: Abakumov, Maxim
  last_name: Abakumov
- first_name: Tatiana O.
  full_name: Abakumova, Tatiana O.
  last_name: Abakumova
- first_name: Inna S.
  full_name: Povolotskaya, Inna S.
  last_name: Povolotskaya
- first_name: Fedor M.
  full_name: Eroshkin, Fedor M.
  last_name: Eroshkin
- first_name: Andrey G.
  full_name: Zaraisky, Andrey G.
  last_name: Zaraisky
- first_name: Alexander S.
  full_name: Mishin, Alexander S.
  last_name: Mishin
- first_name: Sergey V.
  full_name: Dolgov, Sergey V.
  last_name: Dolgov
- first_name: Tatiana Y.
  full_name: Mitiouchkina, Tatiana Y.
  last_name: Mitiouchkina
- first_name: Eugene P.
  full_name: Kopantzev, Eugene P.
  last_name: Kopantzev
- first_name: Hans E.
  full_name: Waldenmaier, Hans E.
  last_name: Waldenmaier
- first_name: Anderson G.
  full_name: Oliveira, Anderson G.
  last_name: Oliveira
- first_name: Yuichi
  full_name: Oba, Yuichi
  last_name: Oba
- first_name: Ekaterina
  full_name: Barsova, Ekaterina
  last_name: Barsova
- first_name: Ekaterina A.
  full_name: Bogdanova, Ekaterina A.
  last_name: Bogdanova
- first_name: Toni
  full_name: Gabaldón, Toni
  last_name: Gabaldón
- first_name: Cassius V.
  full_name: Stevani, Cassius V.
  last_name: Stevani
- first_name: Sergey
  full_name: Lukyanov, Sergey
  last_name: Lukyanov
- first_name: Ivan V.
  full_name: Smirnov, Ivan V.
  last_name: Smirnov
- first_name: Josef I.
  full_name: Gitelson, Josef I.
  last_name: Gitelson
- first_name: Fyodor
  full_name: Kondrashov, Fyodor
  id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
  last_name: Kondrashov
  orcid: 0000-0001-8243-4694
- first_name: Ilia V.
  full_name: Yampolsky, Ilia V.
  last_name: Yampolsky
citation:
  ama: Kotlobay AA, Sarkisyan K, Mokrushina YA, et al. Genetically encodable bioluminescent
    system from fungi. <i>Proceedings of the National Academy of Sciences of the United
    States of America</i>. 2018;115(50):12728-12732. doi:<a href="https://doi.org/10.1073/pnas.1803615115">10.1073/pnas.1803615115</a>
  apa: Kotlobay, A. A., Sarkisyan, K., Mokrushina, Y. A., Marcet-Houben, M., Serebrovskaya,
    E. O., Markina, N. M., … Yampolsky, I. V. (2018). Genetically encodable bioluminescent
    system from fungi. <i>Proceedings of the National Academy of Sciences of the United
    States of America</i>. National Academy of Sciences. <a href="https://doi.org/10.1073/pnas.1803615115">https://doi.org/10.1073/pnas.1803615115</a>
  chicago: Kotlobay, Alexey A., Karen Sarkisyan, Yuliana A. Mokrushina, Marina Marcet-Houben,
    Ekaterina O. Serebrovskaya, Nadezhda M. Markina, Louisa Gonzalez Somermeyer, et
    al. “Genetically Encodable Bioluminescent System from Fungi.” <i>Proceedings of
    the National Academy of Sciences of the United States of America</i>. National
    Academy of Sciences, 2018. <a href="https://doi.org/10.1073/pnas.1803615115">https://doi.org/10.1073/pnas.1803615115</a>.
  ieee: A. A. Kotlobay <i>et al.</i>, “Genetically encodable bioluminescent system
    from fungi,” <i>Proceedings of the National Academy of Sciences of the United
    States of America</i>, vol. 115, no. 50. National Academy of Sciences, pp. 12728–12732,
    2018.
  ista: Kotlobay AA, Sarkisyan K, Mokrushina YA, Marcet-Houben M, Serebrovskaya EO,
    Markina NM, Gonzalez Somermeyer L, Gorokhovatsky AY, Vvedensky A, Purtov KV, Petushkov
    VN, Rodionova NS, Chepurnyh TV, Fakhranurova L, Guglya EB, Ziganshin R, Tsarkova
    AS, Kaskova ZM, Shender V, Abakumov M, Abakumova TO, Povolotskaya IS, Eroshkin
    FM, Zaraisky AG, Mishin AS, Dolgov SV, Mitiouchkina TY, Kopantzev EP, Waldenmaier
    HE, Oliveira AG, Oba Y, Barsova E, Bogdanova EA, Gabaldón T, Stevani CV, Lukyanov
    S, Smirnov IV, Gitelson JI, Kondrashov F, Yampolsky IV. 2018. Genetically encodable
    bioluminescent system from fungi. Proceedings of the National Academy of Sciences
    of the United States of America. 115(50), 12728–12732.
  mla: Kotlobay, Alexey A., et al. “Genetically Encodable Bioluminescent System from
    Fungi.” <i>Proceedings of the National Academy of Sciences of the United States
    of America</i>, vol. 115, no. 50, National Academy of Sciences, 2018, pp. 12728–32,
    doi:<a href="https://doi.org/10.1073/pnas.1803615115">10.1073/pnas.1803615115</a>.
  short: A.A. Kotlobay, K. Sarkisyan, Y.A. Mokrushina, M. Marcet-Houben, E.O. Serebrovskaya,
    N.M. Markina, L. Gonzalez Somermeyer, A.Y. Gorokhovatsky, A. Vvedensky, K.V. Purtov,
    V.N. Petushkov, N.S. Rodionova, T.V. Chepurnyh, L. Fakhranurova, E.B. Guglya,
    R. Ziganshin, A.S. Tsarkova, Z.M. Kaskova, V. Shender, M. Abakumov, T.O. Abakumova,
    I.S. Povolotskaya, F.M. Eroshkin, A.G. Zaraisky, A.S. Mishin, S.V. Dolgov, T.Y.
    Mitiouchkina, E.P. Kopantzev, H.E. Waldenmaier, A.G. Oliveira, Y. Oba, E. Barsova,
    E.A. Bogdanova, T. Gabaldón, C.V. Stevani, S. Lukyanov, I.V. Smirnov, J.I. Gitelson,
    F. Kondrashov, I.V. Yampolsky, Proceedings of the National Academy of Sciences
    of the United States of America 115 (2018) 12728–12732.
date_created: 2018-12-23T22:59:18Z
date_published: 2018-12-11T00:00:00Z
date_updated: 2025-07-10T11:52:58Z
day: '11'
ddc:
- '580'
department:
- _id: FyKo
doi: 10.1073/pnas.1803615115
external_id:
  isi:
  - '000452866000068'
file:
- access_level: open_access
  checksum: 46b2c12185eb2ddb598f4c7b4bd267bf
  content_type: application/pdf
  creator: dernst
  date_created: 2019-02-05T15:21:40Z
  date_updated: 2020-07-14T12:47:11Z
  file_id: '5926'
  file_name: 2018_PNAS_Kotlobay.pdf
  file_size: 1271988
  relation: main_file
file_date_updated: 2020-07-14T12:47:11Z
has_accepted_license: '1'
intvolume: '       115'
isi: 1
issue: '50'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 12728-12732
publication: Proceedings of the National Academy of Sciences of the United States
  of America
publication_identifier:
  issn:
  - 0027-8424
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Genetically encodable bioluminescent system from fungi
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 115
year: '2018'
...
