---
_id: '6368'
abstract:
- lang: eng
text: An optical network of superconducting quantum bits (qubits) is an appealing
platform for quantum communication and distributed quantum computing, but developing
a quantum-compatible link between the microwave and optical domains remains an
outstanding challenge. Operating at T < 100 mK temperatures, as required for quantum
electrical circuits, we demonstrate a mechanically mediated microwave–optical
converter with 47% conversion efficiency, and use a classical feed-forward protocol
to reduce added noise to 38 photons. The feed-forward protocol harnesses our discovery
that noise emitted from the two converter output ports is strongly correlated
because both outputs record thermal motion of the same mechanical mode. We also
discuss a quantum feed-forward protocol that, given high system efficiencies,
would allow quantum information to be transferred even when thermal phonons enter
the mechanical element faster than the electro-optic conversion rate.
arxiv: 1
author:
- first_name: Andrew P
full_name: Higginbotham, Andrew P
id: 4AD6785A-F248-11E8-B48F-1D18A9856A87
last_name: Higginbotham
orcid: 0000-0003-2607-2363
- first_name: P. S.
full_name: Burns, P. S.
last_name: Burns
- first_name: M. D.
full_name: Urmey, M. D.
last_name: Urmey
- first_name: R. W.
full_name: Peterson, R. W.
last_name: Peterson
- first_name: N. S.
full_name: Kampel, N. S.
last_name: Kampel
- first_name: B. M.
full_name: Brubaker, B. M.
last_name: Brubaker
- first_name: G.
full_name: Smith, G.
last_name: Smith
- first_name: K. W.
full_name: Lehnert, K. W.
last_name: Lehnert
- first_name: C. A.
full_name: Regal, C. A.
last_name: Regal
citation:
ama: Higginbotham AP, Burns PS, Urmey MD, et al. Harnessing electro-optic correlations
in an efficient mechanical converter. Nature Physics. 2018;14(10):1038-1042.
doi:10.1038/s41567-018-0210-0
apa: Higginbotham, A. P., Burns, P. S., Urmey, M. D., Peterson, R. W., Kampel, N.
S., Brubaker, B. M., … Regal, C. A. (2018). Harnessing electro-optic correlations
in an efficient mechanical converter. Nature Physics. Springer Nature.
https://doi.org/10.1038/s41567-018-0210-0
chicago: Higginbotham, Andrew P, P. S. Burns, M. D. Urmey, R. W. Peterson, N. S.
Kampel, B. M. Brubaker, G. Smith, K. W. Lehnert, and C. A. Regal. “Harnessing
Electro-Optic Correlations in an Efficient Mechanical Converter.” Nature Physics.
Springer Nature, 2018. https://doi.org/10.1038/s41567-018-0210-0.
ieee: A. P. Higginbotham et al., “Harnessing electro-optic correlations in
an efficient mechanical converter,” Nature Physics, vol. 14, no. 10. Springer
Nature, pp. 1038–1042, 2018.
ista: Higginbotham AP, Burns PS, Urmey MD, Peterson RW, Kampel NS, Brubaker BM,
Smith G, Lehnert KW, Regal CA. 2018. Harnessing electro-optic correlations in
an efficient mechanical converter. Nature Physics. 14(10), 1038–1042.
mla: Higginbotham, Andrew P., et al. “Harnessing Electro-Optic Correlations in an
Efficient Mechanical Converter.” Nature Physics, vol. 14, no. 10, Springer
Nature, 2018, pp. 1038–42, doi:10.1038/s41567-018-0210-0.
short: A.P. Higginbotham, P.S. Burns, M.D. Urmey, R.W. Peterson, N.S. Kampel, B.M.
Brubaker, G. Smith, K.W. Lehnert, C.A. Regal, Nature Physics 14 (2018) 1038–1042.
date_created: 2019-05-03T09:17:20Z
date_published: 2018-10-01T00:00:00Z
date_updated: 2021-01-12T08:07:15Z
day: '01'
doi: 10.1038/s41567-018-0210-0
extern: '1'
external_id:
arxiv:
- '1712.06535'
intvolume: ' 14'
issue: '10'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1712.06535
month: '10'
oa: 1
oa_version: Preprint
page: 1038-1042
publication: Nature Physics
publication_identifier:
issn:
- 1745-2473
- 1745-2481
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Harnessing electro-optic correlations in an efficient mechanical converter
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 14
year: '2018'
...
---
_id: '6369'
abstract:
- lang: eng
text: We construct a metamaterial from radio-frequency harmonic oscillators, and
find two topologically distinct phases resulting from dissipation engineered into
the system. These phases are distinguished by a quantized value of bulk energy
transport. The impulse response of our circuit is measured and used to reconstruct
the band structure and winding number of circuit eigenfunctions around a dark
mode. Our results demonstrate that dissipative topological transport can occur
in a wider class of physical systems than considered before.
article_number: '220301'
arxiv: 1
author:
- first_name: Eric I.
full_name: Rosenthal, Eric I.
last_name: Rosenthal
- first_name: Nicole K.
full_name: Ehrlich, Nicole K.
last_name: Ehrlich
- first_name: Mark S.
full_name: Rudner, Mark S.
last_name: Rudner
- first_name: Andrew P
full_name: Higginbotham, Andrew P
id: 4AD6785A-F248-11E8-B48F-1D18A9856A87
last_name: Higginbotham
orcid: 0000-0003-2607-2363
- first_name: K. W.
full_name: Lehnert, K. W.
last_name: Lehnert
citation:
ama: Rosenthal EI, Ehrlich NK, Rudner MS, Higginbotham AP, Lehnert KW. Topological
phase transition measured in a dissipative metamaterial. Physical Review B.
2018;97(22). doi:10.1103/physrevb.97.220301
apa: Rosenthal, E. I., Ehrlich, N. K., Rudner, M. S., Higginbotham, A. P., &
Lehnert, K. W. (2018). Topological phase transition measured in a dissipative
metamaterial. Physical Review B. American Physical Society (APS). https://doi.org/10.1103/physrevb.97.220301
chicago: Rosenthal, Eric I., Nicole K. Ehrlich, Mark S. Rudner, Andrew P Higginbotham,
and K. W. Lehnert. “Topological Phase Transition Measured in a Dissipative Metamaterial.”
Physical Review B. American Physical Society (APS), 2018. https://doi.org/10.1103/physrevb.97.220301.
ieee: E. I. Rosenthal, N. K. Ehrlich, M. S. Rudner, A. P. Higginbotham, and K. W.
Lehnert, “Topological phase transition measured in a dissipative metamaterial,”
Physical Review B, vol. 97, no. 22. American Physical Society (APS), 2018.
ista: Rosenthal EI, Ehrlich NK, Rudner MS, Higginbotham AP, Lehnert KW. 2018. Topological
phase transition measured in a dissipative metamaterial. Physical Review B. 97(22),
220301.
mla: Rosenthal, Eric I., et al. “Topological Phase Transition Measured in a Dissipative
Metamaterial.” Physical Review B, vol. 97, no. 22, 220301, American Physical
Society (APS), 2018, doi:10.1103/physrevb.97.220301.
short: E.I. Rosenthal, N.K. Ehrlich, M.S. Rudner, A.P. Higginbotham, K.W. Lehnert,
Physical Review B 97 (2018).
date_created: 2019-05-03T09:29:49Z
date_published: 2018-06-04T00:00:00Z
date_updated: 2021-01-12T08:07:16Z
day: '04'
doi: 10.1103/physrevb.97.220301
extern: '1'
external_id:
arxiv:
- '1802.02243'
intvolume: ' 97'
issue: '22'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1802.02243
month: '06'
oa: 1
oa_version: Preprint
publication: Physical Review B
publication_identifier:
issn:
- 2469-9950
- 2469-9969
publication_status: published
publisher: American Physical Society (APS)
quality_controlled: '1'
status: public
title: Topological phase transition measured in a dissipative metamaterial
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 97
year: '2018'
...
---
_id: '64'
abstract:
- lang: eng
text: Tropical geometry, an established field in pure mathematics, is a place where
string theory, mirror symmetry, computational algebra, auction theory, and so
forth meet and influence one another. In this paper, we report on our discovery
of a tropical model with self-organized criticality (SOC) behavior. Our model
is continuous, in contrast to all known models of SOC, and is a certain scaling
limit of the sandpile model, the first and archetypical model of SOC. We describe
how our model is related to pattern formation and proportional growth phenomena
and discuss the dichotomy between continuous and discrete models in several contexts.
Our aim in this context is to present an idealized tropical toy model (cf. Turing
reaction-diffusion model), requiring further investigation.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Nikita
full_name: Kalinin, Nikita
last_name: Kalinin
- first_name: Aldo
full_name: Guzmán Sáenz, Aldo
last_name: Guzmán Sáenz
- first_name: Y
full_name: Prieto, Y
last_name: Prieto
- first_name: Mikhail
full_name: Shkolnikov, Mikhail
id: 35084A62-F248-11E8-B48F-1D18A9856A87
last_name: Shkolnikov
orcid: 0000-0002-4310-178X
- first_name: V
full_name: Kalinina, V
last_name: Kalinina
- first_name: Ernesto
full_name: Lupercio, Ernesto
last_name: Lupercio
citation:
ama: Kalinin N, Guzmán Sáenz A, Prieto Y, Shkolnikov M, Kalinina V, Lupercio E.
Self-organized criticality and pattern emergence through the lens of tropical
geometry. Proceedings of the National Academy of Sciences of the United States
of America. 2018;115(35):E8135-E8142. doi:10.1073/pnas.1805847115
apa: Kalinin, N., Guzmán Sáenz, A., Prieto, Y., Shkolnikov, M., Kalinina, V., &
Lupercio, E. (2018). Self-organized criticality and pattern emergence through
the lens of tropical geometry. Proceedings of the National Academy of Sciences
of the United States of America. National Academy of Sciences. https://doi.org/10.1073/pnas.1805847115
chicago: Kalinin, Nikita, Aldo Guzmán Sáenz, Y Prieto, Mikhail Shkolnikov, V Kalinina,
and Ernesto Lupercio. “Self-Organized Criticality and Pattern Emergence through
the Lens of Tropical Geometry.” Proceedings of the National Academy of Sciences
of the United States of America. National Academy of Sciences, 2018. https://doi.org/10.1073/pnas.1805847115.
ieee: N. Kalinin, A. Guzmán Sáenz, Y. Prieto, M. Shkolnikov, V. Kalinina, and E.
Lupercio, “Self-organized criticality and pattern emergence through the lens of
tropical geometry,” Proceedings of the National Academy of Sciences of the
United States of America, vol. 115, no. 35. National Academy of Sciences,
pp. E8135–E8142, 2018.
ista: Kalinin N, Guzmán Sáenz A, Prieto Y, Shkolnikov M, Kalinina V, Lupercio E.
2018. Self-organized criticality and pattern emergence through the lens of tropical
geometry. Proceedings of the National Academy of Sciences of the United States
of America. 115(35), E8135–E8142.
mla: Kalinin, Nikita, et al. “Self-Organized Criticality and Pattern Emergence through
the Lens of Tropical Geometry.” Proceedings of the National Academy of Sciences
of the United States of America, vol. 115, no. 35, National Academy of Sciences,
2018, pp. E8135–42, doi:10.1073/pnas.1805847115.
short: N. Kalinin, A. Guzmán Sáenz, Y. Prieto, M. Shkolnikov, V. Kalinina, E. Lupercio,
Proceedings of the National Academy of Sciences of the United States of America
115 (2018) E8135–E8142.
date_created: 2018-12-11T11:44:26Z
date_published: 2018-08-28T00:00:00Z
date_updated: 2025-06-03T11:21:16Z
day: '28'
department:
- _id: TaHa
doi: 10.1073/pnas.1805847115
ec_funded: 1
external_id:
arxiv:
- '1806.09153'
isi:
- '000442861600009'
intvolume: ' 115'
isi: 1
issue: '35'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1806.09153
month: '08'
oa: 1
oa_version: Preprint
page: E8135 - E8142
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Proceedings of the National Academy of Sciences of the United States
of America
publication_identifier:
issn:
- 0027-8424
publication_status: published
publisher: National Academy of Sciences
publist_id: '7990'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Self-organized criticality and pattern emergence through the lens of tropical
geometry
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 115
year: '2018'
...
---
OA_place: repository
OA_type: green
_id: '19806'
abstract:
- lang: eng
text: Transition-metal dichalcogenides (TMDs) are renowned for their rich and varied
bulk properties, while their single-layer variants have become one of the most
prominent examples of two-dimensional materials beyond graphene. Their disparate
ground states largely depend on transition metal d-electron-derived electronic
states, on which the vast majority of attention has been concentrated to date.
Here, we focus on the chalcogen-derived states. From density-functional theory
calculations together with spin- and angle-resolved photoemission, we find that
these generically host a co-existence of type-I and type-II three-dimensional
bulk Dirac fermions as well as ladders of topological surface states and surface
resonances. We demonstrate how these naturally arise within a single p-orbital
manifold as a general consequence of a trigonal crystal field, and as such can
be expected across a large number of compounds. Already, we demonstrate their
existence in six separate TMDs, opening routes to tune, and ultimately exploit,
their topological physics.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: M. S.
full_name: Bahramy, M. S.
last_name: Bahramy
- first_name: O. J.
full_name: Clark, O. J.
last_name: Clark
- first_name: B.-J.
full_name: Yang, B.-J.
last_name: Yang
- first_name: J.
full_name: Feng, J.
last_name: Feng
- first_name: L.
full_name: Bawden, L.
last_name: Bawden
- first_name: J. M.
full_name: Riley, J. M.
last_name: Riley
- first_name: I.
full_name: Marković, I.
last_name: Marković
- first_name: F.
full_name: Mazzola, F.
last_name: Mazzola
- first_name: Veronika
full_name: Sunko, Veronika
id: 23cb1cf6-2c7a-11ef-91a4-f72fc19f20b3
last_name: Sunko
orcid: 0000-0003-2724-3523
- first_name: D.
full_name: Biswas, D.
last_name: Biswas
- first_name: S. P.
full_name: Cooil, S. P.
last_name: Cooil
- first_name: M.
full_name: Jorge, M.
last_name: Jorge
- first_name: J. W.
full_name: Wells, J. W.
last_name: Wells
- first_name: M.
full_name: Leandersson, M.
last_name: Leandersson
- first_name: T.
full_name: Balasubramanian, T.
last_name: Balasubramanian
- first_name: J.
full_name: Fujii, J.
last_name: Fujii
- first_name: I.
full_name: Vobornik, I.
last_name: Vobornik
- first_name: J. E.
full_name: Rault, J. E.
last_name: Rault
- first_name: T. K.
full_name: Kim, T. K.
last_name: Kim
- first_name: M.
full_name: Hoesch, M.
last_name: Hoesch
- first_name: K.
full_name: Okawa, K.
last_name: Okawa
- first_name: M.
full_name: Asakawa, M.
last_name: Asakawa
- first_name: T.
full_name: Sasagawa, T.
last_name: Sasagawa
- first_name: T.
full_name: Eknapakul, T.
last_name: Eknapakul
- first_name: W.
full_name: Meevasana, W.
last_name: Meevasana
- first_name: P. D. C.
full_name: King, P. D. C.
last_name: King
citation:
ama: Bahramy MS, Clark OJ, Yang B-J, et al. Ubiquitous formation of bulk Dirac cones
and topological surface states from a single orbital manifold in transition-metal
dichalcogenides. Nature Materials. 2018;17:21-28. doi:10.1038/nmat5031
apa: Bahramy, M. S., Clark, O. J., Yang, B.-J., Feng, J., Bawden, L., Riley, J.
M., … King, P. D. C. (2018). Ubiquitous formation of bulk Dirac cones and topological
surface states from a single orbital manifold in transition-metal dichalcogenides.
Nature Materials. Springer Nature. https://doi.org/10.1038/nmat5031
chicago: Bahramy, M. S., O. J. Clark, B.-J. Yang, J. Feng, L. Bawden, J. M. Riley,
I. Marković, et al. “Ubiquitous Formation of Bulk Dirac Cones and Topological
Surface States from a Single Orbital Manifold in Transition-Metal Dichalcogenides.”
Nature Materials. Springer Nature, 2018. https://doi.org/10.1038/nmat5031.
ieee: M. S. Bahramy et al., “Ubiquitous formation of bulk Dirac cones and
topological surface states from a single orbital manifold in transition-metal
dichalcogenides,” Nature Materials, vol. 17. Springer Nature, pp. 21–28,
2018.
ista: Bahramy MS, Clark OJ, Yang B-J, Feng J, Bawden L, Riley JM, Marković I, Mazzola
F, Sunko V, Biswas D, Cooil SP, Jorge M, Wells JW, Leandersson M, Balasubramanian
T, Fujii J, Vobornik I, Rault JE, Kim TK, Hoesch M, Okawa K, Asakawa M, Sasagawa
T, Eknapakul T, Meevasana W, King PDC. 2018. Ubiquitous formation of bulk Dirac
cones and topological surface states from a single orbital manifold in transition-metal
dichalcogenides. Nature Materials. 17, 21–28.
mla: Bahramy, M. S., et al. “Ubiquitous Formation of Bulk Dirac Cones and Topological
Surface States from a Single Orbital Manifold in Transition-Metal Dichalcogenides.”
Nature Materials, vol. 17, Springer Nature, 2018, pp. 21–28, doi:10.1038/nmat5031.
short: M.S. Bahramy, O.J. Clark, B.-J. Yang, J. Feng, L. Bawden, J.M. Riley, I.
Marković, F. Mazzola, V. Sunko, D. Biswas, S.P. Cooil, M. Jorge, J.W. Wells, M.
Leandersson, T. Balasubramanian, J. Fujii, I. Vobornik, J.E. Rault, T.K. Kim,
M. Hoesch, K. Okawa, M. Asakawa, T. Sasagawa, T. Eknapakul, W. Meevasana, P.D.C.
King, Nature Materials 17 (2018) 21–28.
date_created: 2025-06-10T09:11:05Z
date_published: 2018-01-01T00:00:00Z
date_updated: 2025-06-10T11:12:41Z
day: '01'
doi: 10.1038/nmat5031
extern: '1'
external_id:
arxiv:
- '1702.08177'
pmid:
- '29180775'
intvolume: ' 17'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.1702.08177
month: '01'
oa: 1
oa_version: Preprint
page: 21-28
pmid: 1
publication: Nature Materials
publication_identifier:
eissn:
- 1476-4660
issn:
- 1476-1122
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Ubiquitous formation of bulk Dirac cones and topological surface states from
a single orbital manifold in transition-metal dichalcogenides
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2018'
...
---
OA_place: publisher
OA_type: gold
_id: '19808'
abstract:
- lang: eng
text: The single-band, quasi-two dimensional metals PdCoO2 and PtCoO2 have recently
come to prominence because of their extremely long mean free paths, which establish
them as some of the most electronically pure materials known, and as potential
hosts of previously unobservable regimes of electronic transport. To fully establish
their magnetotransport properties, we have studied the magnetoresistance and Hall
effect in bulk single crystals to which electrical contacts have been made with
high precision using focused ion beam machining. We observe a strong temperature
dependence of the Hall resistivity in small applied fields, linked to a large
violation of Kohler’s rule in the magnetoresistance. We discuss the extent to
which these observations can be accounted for by standard transport theory.
article_number: '66'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Nabhanila
full_name: Nandi, Nabhanila
last_name: Nandi
- first_name: Thomas
full_name: Scaffidi, Thomas
last_name: Scaffidi
- first_name: Pallavi
full_name: Kushwaha, Pallavi
last_name: Kushwaha
- first_name: Seunghyun
full_name: Khim, Seunghyun
last_name: Khim
- first_name: Mark E.
full_name: Barber, Mark E.
last_name: Barber
- first_name: Veronika
full_name: Sunko, Veronika
id: 23cb1cf6-2c7a-11ef-91a4-f72fc19f20b3
last_name: Sunko
orcid: 0000-0003-2724-3523
- first_name: Federico
full_name: Mazzola, Federico
last_name: Mazzola
- first_name: Philip D. C.
full_name: King, Philip D. C.
last_name: King
- first_name: Helge
full_name: Rosner, Helge
last_name: Rosner
- first_name: Philip J. W.
full_name: Moll, Philip J. W.
last_name: Moll
- first_name: Markus
full_name: König, Markus
last_name: König
- first_name: Joel E.
full_name: Moore, Joel E.
last_name: Moore
- first_name: Sean
full_name: Hartnoll, Sean
last_name: Hartnoll
- first_name: Andrew P.
full_name: Mackenzie, Andrew P.
last_name: Mackenzie
citation:
ama: Nandi N, Scaffidi T, Kushwaha P, et al. Unconventional magneto-transport in
ultrapure PdCoO2 and PtCoO2. npj Quantum Materials. 2018;3. doi:10.1038/s41535-018-0138-8
apa: Nandi, N., Scaffidi, T., Kushwaha, P., Khim, S., Barber, M. E., Sunko, V.,
… Mackenzie, A. P. (2018). Unconventional magneto-transport in ultrapure PdCoO2
and PtCoO2. Npj Quantum Materials. Springer Nature. https://doi.org/10.1038/s41535-018-0138-8
chicago: Nandi, Nabhanila, Thomas Scaffidi, Pallavi Kushwaha, Seunghyun Khim, Mark
E. Barber, Veronika Sunko, Federico Mazzola, et al. “Unconventional Magneto-Transport
in Ultrapure PdCoO2 and PtCoO2.” Npj Quantum Materials. Springer Nature,
2018. https://doi.org/10.1038/s41535-018-0138-8.
ieee: N. Nandi et al., “Unconventional magneto-transport in ultrapure PdCoO2
and PtCoO2,” npj Quantum Materials, vol. 3. Springer Nature, 2018.
ista: Nandi N, Scaffidi T, Kushwaha P, Khim S, Barber ME, Sunko V, Mazzola F, King
PDC, Rosner H, Moll PJW, König M, Moore JE, Hartnoll S, Mackenzie AP. 2018. Unconventional
magneto-transport in ultrapure PdCoO2 and PtCoO2. npj Quantum Materials. 3, 66.
mla: Nandi, Nabhanila, et al. “Unconventional Magneto-Transport in Ultrapure PdCoO2
and PtCoO2.” Npj Quantum Materials, vol. 3, 66, Springer Nature, 2018,
doi:10.1038/s41535-018-0138-8.
short: N. Nandi, T. Scaffidi, P. Kushwaha, S. Khim, M.E. Barber, V. Sunko, F. Mazzola,
P.D.C. King, H. Rosner, P.J.W. Moll, M. König, J.E. Moore, S. Hartnoll, A.P. Mackenzie,
Npj Quantum Materials 3 (2018).
date_created: 2025-06-10T09:12:15Z
date_published: 2018-12-18T00:00:00Z
date_updated: 2025-06-10T11:39:41Z
day: '18'
doi: 10.1038/s41535-018-0138-8
extern: '1'
external_id:
arxiv:
- '1804.01896'
has_accepted_license: '1'
intvolume: ' 3'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
main_file_link:
- open_access: '1'
url: https://doi.org/10.1038/s41535-018-0138-8
month: '12'
oa: 1
oa_version: Published Version
publication: npj Quantum Materials
publication_identifier:
issn:
- 2397-4648
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Unconventional magneto-transport in ultrapure PdCoO2 and PtCoO2
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 3
year: '2018'
...
---
OA_place: repository
OA_type: green
_id: '19813'
abstract:
- lang: eng
text: "We study the low-energy surface electronic structure of the transition-metal
dichalcogenide superconductor PdTe2 by spin- and angle-resolved photoemission,
scanning tunneling microscopy, and density-functional theory-based supercell calculations.
Comparing PdTe2 with its sister compound PtSe2, we demonstrate how enhanced interlayer
hopping in the Te-based material drives a band inversion within the antibonding
\U0001D45D-orbital manifold well above the Fermi level. We show how this mediates
spin-polarized topological surface states which form rich multivalley Fermi surfaces
with complex spin textures. Scanning tunneling spectroscopy reveals type-II superconductivity
at the surface, and moreover shows no evidence for an unconventional component
of its superconducting order parameter, despite the presence of topological surface
states."
article_number: '156401'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: O. J.
full_name: Clark, O. J.
last_name: Clark
- first_name: M. J.
full_name: Neat, M. J.
last_name: Neat
- first_name: K.
full_name: Okawa, K.
last_name: Okawa
- first_name: L.
full_name: Bawden, L.
last_name: Bawden
- first_name: I.
full_name: Marković, I.
last_name: Marković
- first_name: F.
full_name: Mazzola, F.
last_name: Mazzola
- first_name: J.
full_name: Feng, J.
last_name: Feng
- first_name: Veronika
full_name: Sunko, Veronika
id: 23cb1cf6-2c7a-11ef-91a4-f72fc19f20b3
last_name: Sunko
orcid: 0000-0003-2724-3523
- first_name: J. M.
full_name: Riley, J. M.
last_name: Riley
- first_name: W.
full_name: Meevasana, W.
last_name: Meevasana
- first_name: J.
full_name: Fujii, J.
last_name: Fujii
- first_name: I.
full_name: Vobornik, I.
last_name: Vobornik
- first_name: T. K.
full_name: Kim, T. K.
last_name: Kim
- first_name: M.
full_name: Hoesch, M.
last_name: Hoesch
- first_name: T.
full_name: Sasagawa, T.
last_name: Sasagawa
- first_name: P.
full_name: Wahl, P.
last_name: Wahl
- first_name: M. S.
full_name: Bahramy, M. S.
last_name: Bahramy
- first_name: P. D. C.
full_name: King, P. D. C.
last_name: King
citation:
ama: Clark OJ, Neat MJ, Okawa K, et al. Fermiology and superconductivity of topological
surface states in PdTe2. Physical Review Letters. 2018;120(15). doi:10.1103/physrevlett.120.156401
apa: Clark, O. J., Neat, M. J., Okawa, K., Bawden, L., Marković, I., Mazzola, F.,
… King, P. D. C. (2018). Fermiology and superconductivity of topological surface
states in PdTe2. Physical Review Letters. American Physical Society. https://doi.org/10.1103/physrevlett.120.156401
chicago: Clark, O. J., M. J. Neat, K. Okawa, L. Bawden, I. Marković, F. Mazzola,
J. Feng, et al. “Fermiology and Superconductivity of Topological Surface States
in PdTe2.” Physical Review Letters. American Physical Society, 2018. https://doi.org/10.1103/physrevlett.120.156401.
ieee: O. J. Clark et al., “Fermiology and superconductivity of topological
surface states in PdTe2,” Physical Review Letters, vol. 120, no. 15. American
Physical Society, 2018.
ista: Clark OJ, Neat MJ, Okawa K, Bawden L, Marković I, Mazzola F, Feng J, Sunko
V, Riley JM, Meevasana W, Fujii J, Vobornik I, Kim TK, Hoesch M, Sasagawa T, Wahl
P, Bahramy MS, King PDC. 2018. Fermiology and superconductivity of topological
surface states in PdTe2. Physical Review Letters. 120(15), 156401.
mla: Clark, O. J., et al. “Fermiology and Superconductivity of Topological Surface
States in PdTe2.” Physical Review Letters, vol. 120, no. 15, 156401, American
Physical Society, 2018, doi:10.1103/physrevlett.120.156401.
short: O.J. Clark, M.J. Neat, K. Okawa, L. Bawden, I. Marković, F. Mazzola, J. Feng,
V. Sunko, J.M. Riley, W. Meevasana, J. Fujii, I. Vobornik, T.K. Kim, M. Hoesch,
T. Sasagawa, P. Wahl, M.S. Bahramy, P.D.C. King, Physical Review Letters 120 (2018).
date_created: 2025-06-10T09:14:51Z
date_published: 2018-04-09T00:00:00Z
date_updated: 2025-06-10T12:16:08Z
day: '09'
doi: 10.1103/physrevlett.120.156401
extern: '1'
external_id:
arxiv:
- '1712.04184'
pmid:
- '29756894'
intvolume: ' 120'
issue: '15'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.1712.04184
month: '04'
oa: 1
oa_version: Preprint
pmid: 1
publication: Physical Review Letters
publication_identifier:
eissn:
- 1079-7114
issn:
- 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Fermiology and superconductivity of topological surface states in PdTe2
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 120
year: '2018'
...
---
OA_place: repository
OA_type: green
_id: '19819'
abstract:
- lang: eng
text: The ability to modulate the collective properties of correlated electron systems
at their interfaces and surfaces underpins the burgeoning field of “designer”
quantum materials. Here, we show how an electronic reconstruction driven by surface
polarity mediates a Stoner-like magnetic instability to itinerant ferromagnetism
at the Pd-terminated surface of the nonmagnetic delafossite oxide metal PdCoO2.
Combining angle-resolved photoemission spectroscopy and density-functional theory
calculations, we show how this leads to a rich multiband surface electronic structure.
We find similar surface state dispersions in PdCrO2, suggesting surface ferromagnetism
persists in this sister compound despite its bulk antiferromagnetic order.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Federico
full_name: Mazzola, Federico
last_name: Mazzola
- first_name: Veronika
full_name: Sunko, Veronika
id: 23cb1cf6-2c7a-11ef-91a4-f72fc19f20b3
last_name: Sunko
orcid: 0000-0003-2724-3523
- first_name: Seunghyun
full_name: Khim, Seunghyun
last_name: Khim
- first_name: Helge
full_name: Rosner, Helge
last_name: Rosner
- first_name: Pallavi
full_name: Kushwaha, Pallavi
last_name: Kushwaha
- first_name: Oliver J.
full_name: Clark, Oliver J.
last_name: Clark
- first_name: Lewis
full_name: Bawden, Lewis
last_name: Bawden
- first_name: Igor
full_name: Marković, Igor
last_name: Marković
- first_name: Timur K.
full_name: Kim, Timur K.
last_name: Kim
- first_name: Moritz
full_name: Hoesch, Moritz
last_name: Hoesch
- first_name: Andrew P.
full_name: Mackenzie, Andrew P.
last_name: Mackenzie
- first_name: Phil D. C.
full_name: King, Phil D. C.
last_name: King
citation:
ama: Mazzola F, Sunko V, Khim S, et al. Itinerant ferromagnetism of the Pd-terminated
polar surface of PdCoO2. Proceedings of the National Academy of Sciences.
2018;115(51):12956-12960. doi:10.1073/pnas.1811873115
apa: Mazzola, F., Sunko, V., Khim, S., Rosner, H., Kushwaha, P., Clark, O. J., …
King, P. D. C. (2018). Itinerant ferromagnetism of the Pd-terminated polar surface
of PdCoO2. Proceedings of the National Academy of Sciences. National Academy
of Sciences. https://doi.org/10.1073/pnas.1811873115
chicago: Mazzola, Federico, Veronika Sunko, Seunghyun Khim, Helge Rosner, Pallavi
Kushwaha, Oliver J. Clark, Lewis Bawden, et al. “Itinerant Ferromagnetism of the
Pd-Terminated Polar Surface of PdCoO2.” Proceedings of the National Academy
of Sciences. National Academy of Sciences, 2018. https://doi.org/10.1073/pnas.1811873115.
ieee: F. Mazzola et al., “Itinerant ferromagnetism of the Pd-terminated polar
surface of PdCoO2,” Proceedings of the National Academy of Sciences, vol.
115, no. 51. National Academy of Sciences, pp. 12956–12960, 2018.
ista: Mazzola F, Sunko V, Khim S, Rosner H, Kushwaha P, Clark OJ, Bawden L, Marković
I, Kim TK, Hoesch M, Mackenzie AP, King PDC. 2018. Itinerant ferromagnetism of
the Pd-terminated polar surface of PdCoO2. Proceedings of the National Academy
of Sciences. 115(51), 12956–12960.
mla: Mazzola, Federico, et al. “Itinerant Ferromagnetism of the Pd-Terminated Polar
Surface of PdCoO2.” Proceedings of the National Academy of Sciences, vol.
115, no. 51, National Academy of Sciences, 2018, pp. 12956–60, doi:10.1073/pnas.1811873115.
short: F. Mazzola, V. Sunko, S. Khim, H. Rosner, P. Kushwaha, O.J. Clark, L. Bawden,
I. Marković, T.K. Kim, M. Hoesch, A.P. Mackenzie, P.D.C. King, Proceedings of
the National Academy of Sciences 115 (2018) 12956–12960.
date_created: 2025-06-10T09:19:14Z
date_published: 2018-12-04T00:00:00Z
date_updated: 2025-06-10T12:40:00Z
day: '04'
doi: 10.1073/pnas.1811873115
extern: '1'
external_id:
arxiv:
- '1710.05392'
pmid:
- '30514820'
intvolume: ' 115'
issue: '51'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.1710.05392
month: '12'
oa: 1
oa_version: Preprint
page: 12956-12960
pmid: 1
publication: Proceedings of the National Academy of Sciences
publication_identifier:
eissn:
- 1091-6490
issn:
- 0027-8424
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Itinerant ferromagnetism of the Pd-terminated polar surface of PdCoO2
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 115
year: '2018'
...
---
_id: '199'
abstract:
- lang: eng
text: Sex-biased genes are central to the study of sexual selection, sexual antagonism,
and sex chromosome evolution. We describe a comprehensive de novo assembled transcriptome
in the common frog Rana temporaria based on five developmental stages and three
adult tissues from both sexes, obtained from a population with karyotypically
homomorphic but genetically differentiated sex chromosomes. This allows the study
of sex-biased gene expression throughout development, and its effect on the rate
of gene evolution while accounting for pleiotropic expression, which is known
to negatively correlate with the evolutionary rate. Overall, sex-biased genes
had little overlap among developmental stages and adult tissues. Late developmental
stages and gonad tissues had the highest numbers of stage-or tissue-specific genes.
We find that pleiotropic gene expression is a better predictor than sex bias for
the evolutionary rate of genes, though it often interacts with sex bias. Although
genetically differentiated, the sex chromosomes were not enriched in sex-biased
genes, possibly due to a very recent arrest of XY recombination. These results
extend our understanding of the developmental dynamics, tissue specificity, and
genomic localization of sex-biased genes.
article_number: '294'
article_processing_charge: No
author:
- first_name: Wen
full_name: Ma, Wen
last_name: Ma
- first_name: Paris
full_name: Veltsos, Paris
last_name: Veltsos
- first_name: Melissa A
full_name: Toups, Melissa A
id: 4E099E4E-F248-11E8-B48F-1D18A9856A87
last_name: Toups
orcid: 0000-0002-9752-7380
- first_name: Nicolas
full_name: Rodrigues, Nicolas
last_name: Rodrigues
- first_name: Roberto
full_name: Sermier, Roberto
last_name: Sermier
- first_name: Daniel
full_name: Jeffries, Daniel
last_name: Jeffries
- first_name: Nicolas
full_name: Perrin, Nicolas
last_name: Perrin
citation:
ama: Ma W, Veltsos P, Toups MA, et al. Tissue specificity and dynamics of sex biased
gene expression in a common frog population with differentiated, yet homomorphic,
sex chromosomes. Genes. 2018;9(6). doi:10.3390/genes9060294
apa: Ma, W., Veltsos, P., Toups, M. A., Rodrigues, N., Sermier, R., Jeffries, D.,
& Perrin, N. (2018). Tissue specificity and dynamics of sex biased gene expression
in a common frog population with differentiated, yet homomorphic, sex chromosomes.
Genes. MDPI. https://doi.org/10.3390/genes9060294
chicago: Ma, Wen, Paris Veltsos, Melissa A Toups, Nicolas Rodrigues, Roberto Sermier,
Daniel Jeffries, and Nicolas Perrin. “Tissue Specificity and Dynamics of Sex Biased
Gene Expression in a Common Frog Population with Differentiated, yet Homomorphic,
Sex Chromosomes.” Genes. MDPI, 2018. https://doi.org/10.3390/genes9060294.
ieee: W. Ma et al., “Tissue specificity and dynamics of sex biased gene expression
in a common frog population with differentiated, yet homomorphic, sex chromosomes,”
Genes, vol. 9, no. 6. MDPI, 2018.
ista: Ma W, Veltsos P, Toups MA, Rodrigues N, Sermier R, Jeffries D, Perrin N. 2018.
Tissue specificity and dynamics of sex biased gene expression in a common frog
population with differentiated, yet homomorphic, sex chromosomes. Genes. 9(6),
294.
mla: Ma, Wen, et al. “Tissue Specificity and Dynamics of Sex Biased Gene Expression
in a Common Frog Population with Differentiated, yet Homomorphic, Sex Chromosomes.”
Genes, vol. 9, no. 6, 294, MDPI, 2018, doi:10.3390/genes9060294.
short: W. Ma, P. Veltsos, M.A. Toups, N. Rodrigues, R. Sermier, D. Jeffries, N.
Perrin, Genes 9 (2018).
date_created: 2018-12-11T11:45:09Z
date_published: 2018-06-12T00:00:00Z
date_updated: 2024-12-11T13:13:35Z
day: '12'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.3390/genes9060294
external_id:
isi:
- '000436494200026'
file:
- access_level: open_access
checksum: 423069beb1cd3cdd25bf3f464b38f1d7
content_type: application/pdf
creator: dernst
date_created: 2019-02-01T07:52:28Z
date_updated: 2020-07-14T12:45:22Z
file_id: '5905'
file_name: 2018_Genes_Ma.pdf
file_size: 3985796
relation: main_file
file_date_updated: 2020-07-14T12:45:22Z
has_accepted_license: '1'
intvolume: ' 9'
isi: 1
issue: '6'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
publication: Genes
publication_status: published
publisher: MDPI
publist_id: '7714'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Tissue specificity and dynamics of sex biased gene expression in a common frog
population with differentiated, yet homomorphic, sex chromosomes
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2018'
...
---
_id: '20'
abstract:
- lang: eng
text: 'Background: Norepinephrine (NE) signaling has a key role in white adipose
tissue (WAT) functions, including lipolysis, free fatty acid liberation and, under
certain conditions, conversion of white into brite (brown-in-white) adipocytes.
However, acute effects of NE stimulation have not been described at the transcriptional
network level. Results: We used RNA-seq to uncover a broad transcriptional response.
The inference of protein-protein and protein-DNA interaction networks allowed
us to identify a set of immediate-early genes (IEGs) with high betweenness, validating
our approach and suggesting a hierarchical control of transcriptional regulation.
In addition, we identified a transcriptional regulatory network with IEGs as master
regulators, including HSF1 and NFIL3 as novel NE-induced IEG candidates. Moreover,
a functional enrichment analysis and gene clustering into functional modules suggest
a crosstalk between metabolic, signaling, and immune responses. Conclusions: Altogether,
our network biology approach explores for the first time the immediate-early systems
level response of human adipocytes to acute sympathetic activation, thereby providing
a first network basis of early cell fate programs and crosstalks between metabolic
and transcriptional networks required for proper WAT function.'
acknowledgement: This work was funded by the German Centre for Diabetes Research (DZD)
and the Austrian Science Fund (FWF, P25729-B19).
article_processing_charge: No
article_type: original
author:
- first_name: Juan
full_name: Higareda Almaraz, Juan
last_name: Higareda Almaraz
- first_name: Michael
full_name: Karbiener, Michael
last_name: Karbiener
- first_name: Maude
full_name: Giroud, Maude
last_name: Giroud
- first_name: Florian
full_name: Pauler, Florian
id: 48EA0138-F248-11E8-B48F-1D18A9856A87
last_name: Pauler
orcid: 0000-0002-7462-0048
- first_name: Teresa
full_name: Gerhalter, Teresa
last_name: Gerhalter
- first_name: Stephan
full_name: Herzig, Stephan
last_name: Herzig
- first_name: Marcel
full_name: Scheideler, Marcel
last_name: Scheideler
citation:
ama: Higareda Almaraz J, Karbiener M, Giroud M, et al. Norepinephrine triggers an
immediate-early regulatory network response in primary human white adipocytes.
BMC Genomics. 2018;19(1). doi:10.1186/s12864-018-5173-0
apa: Higareda Almaraz, J., Karbiener, M., Giroud, M., Pauler, F., Gerhalter, T.,
Herzig, S., & Scheideler, M. (2018). Norepinephrine triggers an immediate-early
regulatory network response in primary human white adipocytes. BMC Genomics.
BioMed Central. https://doi.org/10.1186/s12864-018-5173-0
chicago: Higareda Almaraz, Juan, Michael Karbiener, Maude Giroud, Florian Pauler,
Teresa Gerhalter, Stephan Herzig, and Marcel Scheideler. “Norepinephrine Triggers
an Immediate-Early Regulatory Network Response in Primary Human White Adipocytes.”
BMC Genomics. BioMed Central, 2018. https://doi.org/10.1186/s12864-018-5173-0.
ieee: J. Higareda Almaraz et al., “Norepinephrine triggers an immediate-early
regulatory network response in primary human white adipocytes,” BMC Genomics,
vol. 19, no. 1. BioMed Central, 2018.
ista: Higareda Almaraz J, Karbiener M, Giroud M, Pauler F, Gerhalter T, Herzig S,
Scheideler M. 2018. Norepinephrine triggers an immediate-early regulatory network
response in primary human white adipocytes. BMC Genomics. 19(1).
mla: Higareda Almaraz, Juan, et al. “Norepinephrine Triggers an Immediate-Early
Regulatory Network Response in Primary Human White Adipocytes.” BMC Genomics,
vol. 19, no. 1, BioMed Central, 2018, doi:10.1186/s12864-018-5173-0.
short: J. Higareda Almaraz, M. Karbiener, M. Giroud, F. Pauler, T. Gerhalter, S.
Herzig, M. Scheideler, BMC Genomics 19 (2018).
date_created: 2018-12-11T11:44:12Z
date_published: 2018-11-03T00:00:00Z
date_updated: 2023-09-13T09:10:47Z
day: '03'
ddc:
- '570'
department:
- _id: SiHi
doi: 10.1186/s12864-018-5173-0
external_id:
isi:
- '000450976700002'
file:
- access_level: open_access
checksum: a56516e734dab589dc7f3e1915973b4d
content_type: application/pdf
creator: dernst
date_created: 2018-12-17T14:52:57Z
date_updated: 2020-07-14T12:45:23Z
file_id: '5712'
file_name: 2018_BMCGenomics_Higareda.pdf
file_size: 4629784
relation: main_file
file_date_updated: 2020-07-14T12:45:23Z
has_accepted_license: '1'
intvolume: ' 19'
isi: 1
issue: '1'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
publication: BMC Genomics
publication_identifier:
issn:
- 1471-2164
publication_status: published
publisher: BioMed Central
publist_id: '8035'
quality_controlled: '1'
related_material:
record:
- id: '9807'
relation: research_data
status: public
- id: '9808'
relation: research_data
status: public
scopus_import: '1'
status: public
title: Norepinephrine triggers an immediate-early regulatory network response in primary
human white adipocytes
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 19
year: '2018'
...
---
OA_place: publisher
_id: '200'
abstract:
- lang: eng
text: This thesis is concerned with the inference of current population structure
based on geo-referenced genetic data. The underlying idea is that population structure
affects its spatial genetic structure. Therefore, genotype information can be
utilized to estimate important demographic parameters such as migration rates.
These indirect estimates of population structure have become very attractive,
as genotype data is now widely available. However, there also has been much concern
about these approaches. Importantly, genetic structure can be influenced by many
complex patterns, which often cannot be disentangled. Moreover, many methods merely
fit heuristic patterns of genetic structure, and do not build upon population
genetics theory. Here, I describe two novel inference methods that address these
shortcomings. In Chapter 2, I introduce an inference scheme based on a new type
of signal, identity by descent (IBD) blocks. Recently, it has become feasible
to detect such long blocks of genome shared between pairs of samples. These blocks
are direct traces of recent coalescence events. As such, they contain ample signal
for inferring recent demography. I examine sharing of IBD blocks in two-dimensional
populations with local migration. Using a diffusion approximation, I derive formulas
for an isolation by distance pattern of long IBD blocks and show that sharing
of long IBD blocks approaches rapid exponential decay for growing sample distance.
I describe an inference scheme based on these results. It can robustly estimate
the dispersal rate and population density, which is demonstrated on simulated
data. I also show an application to estimate mean migration and the rate of recent
population growth within Eastern Europe. Chapter 3 is about a novel method to
estimate barriers to gene flow in a two dimensional population. This inference
scheme utilizes geographically localized allele frequency fluctuations - a classical
isolation by distance signal. The strength of these local fluctuations increases
on average next to a barrier, and there is less correlation across it. I again
use a framework of diffusion of ancestral lineages to model this effect, and provide
an efficient numerical implementation to fit the results to geo-referenced biallelic
SNP data. This inference scheme is able to robustly estimate strong barriers to
gene flow, as tests on simulated data confirm.
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Harald
full_name: Ringbauer, Harald
id: 417FCFF4-F248-11E8-B48F-1D18A9856A87
last_name: Ringbauer
orcid: 0000-0002-4884-9682
citation:
ama: Ringbauer H. Inferring recent demography from spatial genetic structure. 2018.
doi:10.15479/AT:ISTA:th_963
apa: Ringbauer, H. (2018). Inferring recent demography from spatial genetic structure.
Institute of Science and Technology Austria. https://doi.org/10.15479/AT:ISTA:th_963
chicago: Ringbauer, Harald. “Inferring Recent Demography from Spatial Genetic Structure.”
Institute of Science and Technology Austria, 2018. https://doi.org/10.15479/AT:ISTA:th_963.
ieee: H. Ringbauer, “Inferring recent demography from spatial genetic structure,”
Institute of Science and Technology Austria, 2018.
ista: Ringbauer H. 2018. Inferring recent demography from spatial genetic structure.
Institute of Science and Technology Austria.
mla: Ringbauer, Harald. Inferring Recent Demography from Spatial Genetic Structure.
Institute of Science and Technology Austria, 2018, doi:10.15479/AT:ISTA:th_963.
short: H. Ringbauer, Inferring Recent Demography from Spatial Genetic Structure,
Institute of Science and Technology Austria, 2018.
corr_author: '1'
date_created: 2018-12-11T11:45:10Z
date_published: 2018-02-21T00:00:00Z
date_updated: 2026-04-08T14:06:37Z
day: '21'
ddc:
- '576'
degree_awarded: PhD
department:
- _id: NiBa
doi: 10.15479/AT:ISTA:th_963
file:
- access_level: open_access
checksum: 8cc534d2b528ae017acf80874cce48c9
content_type: application/pdf
creator: system
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has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/4.0/
month: '02'
oa: 1
oa_version: Published Version
page: '146'
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '7713'
pubrep_id: '963'
related_material:
record:
- id: '563'
relation: part_of_dissertation
status: public
- id: '1074'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
title: Inferring recent demography from spatial genetic structure
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2018'
...
---
_id: '2015'
abstract:
- lang: eng
text: We consider the problem of learning a Bayesian network or directed acyclic
graph model from observational data. A number of constraint‐based, score‐based
and hybrid algorithms have been developed for this purpose. Statistical consistency
guarantees of these algorithms rely on the faithfulness assumption, which has
been shown to be restrictive especially for graphs with cycles in the skeleton.
We here propose the sparsest permutation (SP) algorithm, showing that learning
Bayesian networks is possible under strictly weaker assumptions than faithfulness.
This comes at a computational price, thereby indicating a statistical‐computational
trade‐off for causal inference algorithms. In the Gaussian noiseless setting,
we prove that the SP algorithm boils down to finding the permutation of the variables
with the sparsest Cholesky decomposition of the inverse covariance matrix, which
is equivalent to ℓ0‐penalized maximum likelihood estimation. We end with a simulation
study showing that in line with the proven stronger consistency guarantees, and
the SP algorithm compares favourably to standard causal inference algorithms in
terms of accuracy for a given sample size.
article_number: e183
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Garvesh
full_name: Raskutti, Garvesh
last_name: Raskutti
- first_name: Caroline
full_name: Uhler, Caroline
id: 49ADD78E-F248-11E8-B48F-1D18A9856A87
last_name: Uhler
orcid: 0000-0002-7008-0216
citation:
ama: Raskutti G, Uhler C. Learning directed acyclic graphs based on sparsest permutations.
STAT. 2018;7(1). doi:10.1002/sta4.183
apa: Raskutti, G., & Uhler, C. (2018). Learning directed acyclic graphs based
on sparsest permutations. STAT. Wiley. https://doi.org/10.1002/sta4.183
chicago: Raskutti, Garvesh, and Caroline Uhler. “Learning Directed Acyclic Graphs
Based on Sparsest Permutations.” STAT. Wiley, 2018. https://doi.org/10.1002/sta4.183.
ieee: G. Raskutti and C. Uhler, “Learning directed acyclic graphs based on sparsest
permutations,” STAT, vol. 7, no. 1. Wiley, 2018.
ista: Raskutti G, Uhler C. 2018. Learning directed acyclic graphs based on sparsest
permutations. STAT. 7(1), e183.
mla: Raskutti, Garvesh, and Caroline Uhler. “Learning Directed Acyclic Graphs Based
on Sparsest Permutations.” STAT, vol. 7, no. 1, e183, Wiley, 2018, doi:10.1002/sta4.183.
short: G. Raskutti, C. Uhler, STAT 7 (2018).
date_created: 2018-12-11T11:55:13Z
date_published: 2018-04-17T00:00:00Z
date_updated: 2021-01-12T06:54:44Z
day: '17'
doi: 10.1002/sta4.183
extern: '1'
external_id:
arxiv:
- '1307.0366'
intvolume: ' 7'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1307.0366
month: '04'
oa: 1
oa_version: Preprint
publication: STAT
publication_status: published
publisher: Wiley
publist_id: '5061'
quality_controlled: '1'
status: public
title: Learning directed acyclic graphs based on sparsest permutations
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2018'
...
---
OA_place: repository
OA_type: green
_id: '203'
abstract:
- lang: eng
text: Asymmetric auxin distribution is instrumental for the differential growth
that causes organ bending on tropic stimuli and curvatures during plant development.
Local differences in auxin concentrations are achieved mainly by polarized cellular
distribution of PIN auxin transporters, but whether other mechanisms involving
auxin homeostasis are also relevant for the formation of auxin gradients is not
clear. Here we show that auxin methylation is required for asymmetric auxin distribution
across the hypocotyl, particularly during its response to gravity. We found that
loss-of-function mutants in Arabidopsis IAA CARBOXYL METHYLTRANSFERASE1 (IAMT1)
prematurely unfold the apical hook, and that their hypocotyls are impaired in
gravitropic reorientation. This defect is linked to an auxin-dependent increase
in PIN gene expression, leading to an increased polar auxin transport and lack
of asymmetric distribution of PIN3 in the iamt1 mutant. Gravitropic reorientation
in the iamt1 mutant could be restored with either endodermis-specific expression
of IAMT1 or partial inhibition of polar auxin transport, which also results in
normal PIN gene expression levels. We propose that IAA methylation is necessary
in gravity-sensing cells to restrict polar auxin transport within the range of
auxin levels that allow for differential responses.
article_processing_charge: No
article_type: original
author:
- first_name: Mohamad
full_name: Abbas, Mohamad
id: 47E8FC1C-F248-11E8-B48F-1D18A9856A87
last_name: Abbas
- first_name: García J
full_name: Hernández, García J
last_name: Hernández
- first_name: Stephan
full_name: Pollmann, Stephan
last_name: Pollmann
- first_name: Sophia L
full_name: Samodelov, Sophia L
last_name: Samodelov
- first_name: Martina
full_name: Kolb, Martina
last_name: Kolb
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Ulrich Z
full_name: Hammes, Ulrich Z
last_name: Hammes
- first_name: Matias D
full_name: Zurbriggen, Matias D
last_name: Zurbriggen
- first_name: Miguel
full_name: Blázquez, Miguel
last_name: Blázquez
- first_name: David
full_name: Alabadí, David
last_name: Alabadí
citation:
ama: Abbas M, Hernández GJ, Pollmann S, et al. Auxin methylation is required for
differential growth in Arabidopsis. PNAS. 2018;115(26):6864-6869. doi:10.1073/pnas.1806565115
apa: Abbas, M., Hernández, G. J., Pollmann, S., Samodelov, S. L., Kolb, M., Friml,
J., … Alabadí, D. (2018). Auxin methylation is required for differential growth
in Arabidopsis. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.1806565115
chicago: Abbas, Mohamad, García J Hernández, Stephan Pollmann, Sophia L Samodelov,
Martina Kolb, Jiří Friml, Ulrich Z Hammes, Matias D Zurbriggen, Miguel Blázquez,
and David Alabadí. “Auxin Methylation Is Required for Differential Growth in Arabidopsis.”
PNAS. National Academy of Sciences, 2018. https://doi.org/10.1073/pnas.1806565115.
ieee: M. Abbas et al., “Auxin methylation is required for differential growth
in Arabidopsis,” PNAS, vol. 115, no. 26. National Academy of Sciences,
pp. 6864–6869, 2018.
ista: Abbas M, Hernández GJ, Pollmann S, Samodelov SL, Kolb M, Friml J, Hammes UZ,
Zurbriggen MD, Blázquez M, Alabadí D. 2018. Auxin methylation is required for
differential growth in Arabidopsis. PNAS. 115(26), 6864–6869.
mla: Abbas, Mohamad, et al. “Auxin Methylation Is Required for Differential Growth
in Arabidopsis.” PNAS, vol. 115, no. 26, National Academy of Sciences,
2018, pp. 6864–69, doi:10.1073/pnas.1806565115.
short: M. Abbas, G.J. Hernández, S. Pollmann, S.L. Samodelov, M. Kolb, J. Friml,
U.Z. Hammes, M.D. Zurbriggen, M. Blázquez, D. Alabadí, PNAS 115 (2018) 6864–6869.
date_created: 2018-12-11T11:45:11Z
date_published: 2018-06-26T00:00:00Z
date_updated: 2026-04-28T08:29:26Z
day: '26'
department:
- _id: JiFr
doi: 10.1073/pnas.1806565115
ec_funded: 1
external_id:
isi:
- '000436245000096'
intvolume: ' 115'
isi: 1
issue: '26'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://eprints.nottingham.ac.uk/52388/
month: '06'
oa: 1
oa_version: Submitted Version
page: 6864-6869
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '282300'
name: Polarity and subcellular dynamics in plants
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '7710'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Auxin methylation is required for differential growth in Arabidopsis
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 115
year: '2018'
...
---
_id: '10357'
abstract:
- lang: eng
text: The misfolding and aggregation of proteins into linear fibrils is widespread
in human biology, for example, in connection with amyloid formation and the pathology
of neurodegenerative disorders such as Alzheimer’s and Parkinson’s diseases. The
oligomeric species that are formed in the early stages of protein aggregation
are of great interest, having been linked with the cellular toxicity associated
with these conditions. However, these species are not characterized in any detail
experimentally, and their properties are not well understood. Many of these species
have been found to have approximately spherical morphology and to be held together
by hydrophobic interactions. We present here an analytical statistical mechanical
model of globular oligomer formation from simple idealized amphiphilic protein
monomers and show that this correlates well with Monte Carlo simulations of oligomer
formation. We identify the controlling parameters of the model, which are closely
related to simple quantities that may be fitted directly from experiment. We predict
that globular oligomers are unlikely to form at equilibrium in many polypeptide
systems but instead form transiently in the early stages of amyloid formation.
We contrast the globular model of oligomer formation to a well-established model
of linear oligomer formation, highlighting how the differing ensemble properties
of linear and globular oligomers offer a potential strategy for characterizing
oligomers from experimental measurements.
acknowledgement: We acknowledge support from the Schiff Foundation (A.J.D.), the Royal
Society (A.Š.), the Academy of Medical Sciences and Wellcome Trust (A.Š.), Peterhouse,
Cambridge (T.C.T.M.), the Swiss National Science foundation (T.C.T.M.), the Wellcome
Trust (T.P.J.K.), the Cambridge Centre for Misfolding Diseases (T.P.J.K.), the BBSRC
(T.P.J.K.), the Frances and Augustus Newman foundation (T.P.J.K.). The research
leading to these results has received funding from the European Research Council
under the European Union’s Seventh Framework Programme (Grant FP7/2007-2013) through
the ERC Grant PhysProt (Agreement No. 337969). We thank Daan Frenkel for several
useful discussions.
article_processing_charge: No
article_type: original
author:
- first_name: Alexander J.
full_name: Dear, Alexander J.
last_name: Dear
- first_name: Anđela
full_name: Šarić, Anđela
id: bf63d406-f056-11eb-b41d-f263a6566d8b
last_name: Šarić
orcid: 0000-0002-7854-2139
- first_name: Thomas C. T.
full_name: Michaels, Thomas C. T.
last_name: Michaels
- first_name: Christopher M.
full_name: Dobson, Christopher M.
last_name: Dobson
- first_name: Tuomas P. J.
full_name: Knowles, Tuomas P. J.
last_name: Knowles
citation:
ama: Dear AJ, Šarić A, Michaels TCT, Dobson CM, Knowles TPJ. Statistical mechanics
of globular oligomer formation by protein molecules. The Journal of Physical
Chemistry B. 2018;122(49):11721-11730. doi:10.1021/acs.jpcb.8b07805
apa: Dear, A. J., Šarić, A., Michaels, T. C. T., Dobson, C. M., & Knowles, T.
P. J. (2018). Statistical mechanics of globular oligomer formation by protein
molecules. The Journal of Physical Chemistry B. American Chemical Society.
https://doi.org/10.1021/acs.jpcb.8b07805
chicago: Dear, Alexander J., Anđela Šarić, Thomas C. T. Michaels, Christopher M.
Dobson, and Tuomas P. J. Knowles. “Statistical Mechanics of Globular Oligomer
Formation by Protein Molecules.” The Journal of Physical Chemistry B. American
Chemical Society, 2018. https://doi.org/10.1021/acs.jpcb.8b07805.
ieee: A. J. Dear, A. Šarić, T. C. T. Michaels, C. M. Dobson, and T. P. J. Knowles,
“Statistical mechanics of globular oligomer formation by protein molecules,” The
Journal of Physical Chemistry B, vol. 122, no. 49. American Chemical Society,
pp. 11721–11730, 2018.
ista: Dear AJ, Šarić A, Michaels TCT, Dobson CM, Knowles TPJ. 2018. Statistical
mechanics of globular oligomer formation by protein molecules. The Journal of
Physical Chemistry B. 122(49), 11721–11730.
mla: Dear, Alexander J., et al. “Statistical Mechanics of Globular Oligomer Formation
by Protein Molecules.” The Journal of Physical Chemistry B, vol. 122, no.
49, American Chemical Society, 2018, pp. 11721–30, doi:10.1021/acs.jpcb.8b07805.
short: A.J. Dear, A. Šarić, T.C.T. Michaels, C.M. Dobson, T.P.J. Knowles, The Journal
of Physical Chemistry B 122 (2018) 11721–11730.
date_created: 2021-11-26T11:55:12Z
date_published: 2018-10-18T00:00:00Z
date_updated: 2021-11-26T12:40:02Z
day: '18'
doi: 10.1021/acs.jpcb.8b07805
extern: '1'
external_id:
pmid:
- '30336667'
intvolume: ' 122'
issue: '49'
keyword:
- materials chemistry
language:
- iso: eng
month: '10'
oa_version: None
page: 11721-11730
pmid: 1
publication: The Journal of Physical Chemistry B
publication_identifier:
eissn:
- 1520-5207
issn:
- 1520-6106
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Statistical mechanics of globular oligomer formation by protein molecules
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 122
year: '2018'
...
---
_id: '10358'
abstract:
- lang: eng
text: Probing reaction mechanisms of supramolecular processes in soft and biological
matter, such as protein aggregation, is inherently challenging. This is because
these processes involve multiple molecular mechanisms that are associated with
the rearrangement of large numbers of weak bonds, resulting in complex free energy
landscapes with many kinetic barriers. Reaction rate measurements at different
temperatures can offer unprecedented insights into the underlying molecular mechanisms.
However, to be able to interpret such measurements, a key challenge is to establish
which properties of the complex free energy landscapes are probed by the reaction
rate. Here, we present a reaction rate theory for supramolecular kinetics based
on Kramers theory of diffusive reactions over multiple kinetic barriers. We find
that reaction rates for protein aggregation are of the Arrhenius–Eyring type and
that the associated activation energies probe only one relevant barrier along
the respective free energy landscapes. We apply this advancement to interpret,
in experiments and in coarse-grained computer simulations, reaction rates of amyloid
aggregation in terms of molecular mechanisms and associated thermodynamic signatures.
These results suggest a practical extension of the concept of rate-determining
steps for complex supramolecular processes and establish a general platform for
probing the underlying energy landscape using kinetic measurements.
acknowledgement: We thank Claudia Flandoli for the help with illustrations.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Thomas C. T.
full_name: Michaels, Thomas C. T.
last_name: Michaels
- first_name: Lucie X.
full_name: Liu, Lucie X.
last_name: Liu
- first_name: Samo
full_name: Curk, Samo
last_name: Curk
- first_name: Peter G.
full_name: Bolhuis, Peter G.
last_name: Bolhuis
- first_name: Anđela
full_name: Šarić, Anđela
id: bf63d406-f056-11eb-b41d-f263a6566d8b
last_name: Šarić
orcid: 0000-0002-7854-2139
- first_name: Tuomas P. J.
full_name: Knowles, Tuomas P. J.
last_name: Knowles
citation:
ama: 'Michaels TCT, Liu LX, Curk S, Bolhuis PG, Šarić A, Knowles TPJ. Reaction rate
theory for supramolecular kinetics: application to protein aggregation. Molecular
Physics. 2018;116(21-22):3055-3065. doi:10.1080/00268976.2018.1474280'
apa: 'Michaels, T. C. T., Liu, L. X., Curk, S., Bolhuis, P. G., Šarić, A., &
Knowles, T. P. J. (2018). Reaction rate theory for supramolecular kinetics: application
to protein aggregation. Molecular Physics. Taylor & Francis. https://doi.org/10.1080/00268976.2018.1474280'
chicago: 'Michaels, Thomas C. T., Lucie X. Liu, Samo Curk, Peter G. Bolhuis, Anđela
Šarić, and Tuomas P. J. Knowles. “Reaction Rate Theory for Supramolecular Kinetics:
Application to Protein Aggregation.” Molecular Physics. Taylor & Francis,
2018. https://doi.org/10.1080/00268976.2018.1474280.'
ieee: 'T. C. T. Michaels, L. X. Liu, S. Curk, P. G. Bolhuis, A. Šarić, and T. P.
J. Knowles, “Reaction rate theory for supramolecular kinetics: application to
protein aggregation,” Molecular Physics, vol. 116, no. 21–22. Taylor &
Francis, pp. 3055–3065, 2018.'
ista: 'Michaels TCT, Liu LX, Curk S, Bolhuis PG, Šarić A, Knowles TPJ. 2018. Reaction
rate theory for supramolecular kinetics: application to protein aggregation. Molecular
Physics. 116(21–22), 3055–3065.'
mla: 'Michaels, Thomas C. T., et al. “Reaction Rate Theory for Supramolecular Kinetics:
Application to Protein Aggregation.” Molecular Physics, vol. 116, no. 21–22,
Taylor & Francis, 2018, pp. 3055–65, doi:10.1080/00268976.2018.1474280.'
short: T.C.T. Michaels, L.X. Liu, S. Curk, P.G. Bolhuis, A. Šarić, T.P.J. Knowles,
Molecular Physics 116 (2018) 3055–3065.
date_created: 2021-11-26T12:08:02Z
date_published: 2018-05-24T00:00:00Z
date_updated: 2021-11-26T12:39:58Z
day: '24'
doi: 10.1080/00268976.2018.1474280
extern: '1'
external_id:
arxiv:
- '1803.04851'
intvolume: ' 116'
issue: 21-22
keyword:
- physical chemistry
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1803.04851
month: '05'
oa: 1
oa_version: Preprint
page: 3055-3065
publication: Molecular Physics
publication_identifier:
eissn:
- 1362-3028
issn:
- 0026-8976
publication_status: published
publisher: Taylor & Francis
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Reaction rate theory for supramolecular kinetics: application to protein aggregation'
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 116
year: '2018'
...
---
_id: '10359'
abstract:
- lang: eng
text: Biological membranes typically contain a large number of different components
dispersed in small concentrations in the main membrane phase, including proteins,
sugars, and lipids of varying geometrical properties. Most of these components
do not bind the cargo. Here, we show that such “inert” components can be crucial
for the precise control of cross-membrane trafficking. Using a statistical mechanics
model and molecular dynamics simulations, we demonstrate that the presence of
inert membrane components of small isotropic curvatures dramatically influences
cargo endocytosis, even if the total spontaneous curvature of such a membrane
remains unchanged. Curved lipids, such as cholesterol, as well as asymmetrically
included proteins and tethered sugars can, therefore, actively participate in
the control of the membrane trafficking of nanoscopic cargo. We find that even
a low-level expression of curved inert membrane components can determine the membrane
selectivity toward the cargo size and can be used to selectively target membranes
of certain compositions. Our results suggest a robust and general method of controlling
cargo trafficking by adjusting the membrane composition without needing to alter
the concentration of receptors or the average membrane curvature. This study indicates
that cells can prepare for any trafficking event by incorporating curved inert
components in either of the membrane leaflets.
acknowledgement: We acknowledge discussions with Giuseppe Battaglia as well as support
from the Herchel Smith scholarship (T.C.), the CAS PIFI fellowship (T.C.), the UCL
Institute for the Physics of Living Systems (T.C. and A.Š.), the Austrian Academy
of Sciences through a DOC fellowship (P.W.), the European Union Horizon 2020 programme
under ETN grant no. 674979-NANOTRANS and FET grant no. 766972-NANOPHLOW (J.D. and
D.F.), the Engineering and Physical Sciences Research Council (D.F. and A.Š.), the
Academy of Medical Sciences and Wellcome Trust (A.Š.), and the Royal Society (A.Š.).
We thank Claudia Flandoli for help with Figure 1.
article_processing_charge: No
article_type: original
author:
- first_name: Tine
full_name: Curk, Tine
last_name: Curk
- first_name: Peter
full_name: Wirnsberger, Peter
last_name: Wirnsberger
- first_name: Jure
full_name: Dobnikar, Jure
last_name: Dobnikar
- first_name: Daan
full_name: Frenkel, Daan
last_name: Frenkel
- first_name: Anđela
full_name: Šarić, Anđela
id: bf63d406-f056-11eb-b41d-f263a6566d8b
last_name: Šarić
orcid: 0000-0002-7854-2139
citation:
ama: Curk T, Wirnsberger P, Dobnikar J, Frenkel D, Šarić A. Controlling cargo trafficking
in multicomponent membranes. Nano Letters. 2018;18(9):5350-5356. doi:10.1021/acs.nanolett.8b00786
apa: Curk, T., Wirnsberger, P., Dobnikar, J., Frenkel, D., & Šarić, A. (2018).
Controlling cargo trafficking in multicomponent membranes. Nano Letters.
American Chemical Society. https://doi.org/10.1021/acs.nanolett.8b00786
chicago: Curk, Tine, Peter Wirnsberger, Jure Dobnikar, Daan Frenkel, and Anđela
Šarić. “Controlling Cargo Trafficking in Multicomponent Membranes.” Nano Letters.
American Chemical Society, 2018. https://doi.org/10.1021/acs.nanolett.8b00786.
ieee: T. Curk, P. Wirnsberger, J. Dobnikar, D. Frenkel, and A. Šarić, “Controlling
cargo trafficking in multicomponent membranes,” Nano Letters, vol. 18,
no. 9. American Chemical Society, pp. 5350–5356, 2018.
ista: Curk T, Wirnsberger P, Dobnikar J, Frenkel D, Šarić A. 2018. Controlling cargo
trafficking in multicomponent membranes. Nano Letters. 18(9), 5350–5356.
mla: Curk, Tine, et al. “Controlling Cargo Trafficking in Multicomponent Membranes.”
Nano Letters, vol. 18, no. 9, American Chemical Society, 2018, pp. 5350–56,
doi:10.1021/acs.nanolett.8b00786.
short: T. Curk, P. Wirnsberger, J. Dobnikar, D. Frenkel, A. Šarić, Nano Letters
18 (2018) 5350–5356.
date_created: 2021-11-26T12:15:47Z
date_published: 2018-04-18T00:00:00Z
date_updated: 2021-11-26T15:14:08Z
day: '18'
doi: 10.1021/acs.nanolett.8b00786
extern: '1'
external_id:
pmid:
- '29667410'
intvolume: ' 18'
issue: '9'
keyword:
- mechanical engineering
- condensed matter physics
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1712.10147
month: '04'
oa: 1
oa_version: Preprint
page: 5350-5356
pmid: 1
publication: Nano Letters
publication_identifier:
eissn:
- 1530-6992
issn:
- 1530-6984
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Controlling cargo trafficking in multicomponent membranes
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 18
year: '2018'
...
---
_id: '10360'
abstract:
- lang: eng
text: Mapping free-energy landscapes has proved to be a powerful tool for studying
reaction mechanisms. Many complex biomolecular assembly processes, however, have
remained challenging to access using this approach, including the aggregation
of peptides and proteins into amyloid fibrils implicated in a range of disorders.
Here, we generalize the strategy used to probe free-energy landscapes in protein
folding to determine the activation energies and entropies that characterize each
of the molecular steps in the aggregation of the amyloid-β peptide (Aβ42), which
is associated with Alzheimer’s disease. Our results reveal that interactions between
monomeric Aβ42 and amyloid fibrils during fibril-dependent secondary nucleation
fundamentally reverse the thermodynamic signature of this process relative to
primary nucleation, even though both processes generate aggregates from soluble
peptides. By mapping the energetic and entropic contributions along the reaction
trajectories, we show that the catalytic efficiency of Aβ42 fibril surfaces results
from the enthalpic stabilization of adsorbing peptides in conformations amenable
to nucleation, resulting in a dramatic lowering of the activation energy for nucleation.
acknowledgement: We thank B. Jönsson and I. André for helpful discussions. We acknowledge
financial support from the Schiff Foundation (S.I.A.C.), St John’s College, Cambridge
(S.I.A.C.), the Royal Physiographic Society (R.C.), the Research School FLÄK of
Lund University (S.L., R.C.), the Swedish Research Council (S.L.) and its Linneaus
Centre Organizing Molecular Matter (S.L.), the Crafoord Foundation (S.L.), Alzheimerfonden
(S.L.), the European Research Council (S.L.), NanoLund (S.L.), Knut and Alice Wallenberg
Foundation (S.L.), Peterhouse, Cambridge (T.C.T.M.), the Swiss National Science
Foundation (T.C.T.M.), Magdalene College, Cambridge (A.K.B.), the Leverhulme Trust
(A.K.B.), the Royal Society (A.Š.), the Academy of Medical Sciences (A.Š.), the
Wellcome Trust (C.M.D., T.P.J.K., A.Š.), and the Centre for Misfolding Diseases
(C.M.D., T.P.J.K, M.V.). A.K.B. thanks the Alzheimer Forschung Initiative (AFI).
article_processing_charge: No
article_type: original
author:
- first_name: Samuel I. A.
full_name: Cohen, Samuel I. A.
last_name: Cohen
- first_name: Risto
full_name: Cukalevski, Risto
last_name: Cukalevski
- first_name: Thomas C. T.
full_name: Michaels, Thomas C. T.
last_name: Michaels
- first_name: Anđela
full_name: Šarić, Anđela
id: bf63d406-f056-11eb-b41d-f263a6566d8b
last_name: Šarić
orcid: 0000-0002-7854-2139
- first_name: Mattias
full_name: Törnquist, Mattias
last_name: Törnquist
- first_name: Michele
full_name: Vendruscolo, Michele
last_name: Vendruscolo
- first_name: Christopher M.
full_name: Dobson, Christopher M.
last_name: Dobson
- first_name: Alexander K.
full_name: Buell, Alexander K.
last_name: Buell
- first_name: Tuomas P. J.
full_name: Knowles, Tuomas P. J.
last_name: Knowles
- first_name: Sara
full_name: Linse, Sara
last_name: Linse
citation:
ama: Cohen SIA, Cukalevski R, Michaels TCT, et al. Distinct thermodynamic signatures
of oligomer generation in the aggregation of the amyloid-β peptide. Nature
Chemistry. 2018;10(5):523-531. doi:10.1038/s41557-018-0023-x
apa: Cohen, S. I. A., Cukalevski, R., Michaels, T. C. T., Šarić, A., Törnquist,
M., Vendruscolo, M., … Linse, S. (2018). Distinct thermodynamic signatures of
oligomer generation in the aggregation of the amyloid-β peptide. Nature Chemistry.
Springer Nature. https://doi.org/10.1038/s41557-018-0023-x
chicago: Cohen, Samuel I. A., Risto Cukalevski, Thomas C. T. Michaels, Anđela Šarić,
Mattias Törnquist, Michele Vendruscolo, Christopher M. Dobson, Alexander K. Buell,
Tuomas P. J. Knowles, and Sara Linse. “Distinct Thermodynamic Signatures of Oligomer
Generation in the Aggregation of the Amyloid-β Peptide.” Nature Chemistry.
Springer Nature, 2018. https://doi.org/10.1038/s41557-018-0023-x.
ieee: S. I. A. Cohen et al., “Distinct thermodynamic signatures of oligomer
generation in the aggregation of the amyloid-β peptide,” Nature Chemistry,
vol. 10, no. 5. Springer Nature, pp. 523–531, 2018.
ista: Cohen SIA, Cukalevski R, Michaels TCT, Šarić A, Törnquist M, Vendruscolo M,
Dobson CM, Buell AK, Knowles TPJ, Linse S. 2018. Distinct thermodynamic signatures
of oligomer generation in the aggregation of the amyloid-β peptide. Nature Chemistry.
10(5), 523–531.
mla: Cohen, Samuel I. A., et al. “Distinct Thermodynamic Signatures of Oligomer
Generation in the Aggregation of the Amyloid-β Peptide.” Nature Chemistry,
vol. 10, no. 5, Springer Nature, 2018, pp. 523–31, doi:10.1038/s41557-018-0023-x.
short: S.I.A. Cohen, R. Cukalevski, T.C.T. Michaels, A. Šarić, M. Törnquist, M.
Vendruscolo, C.M. Dobson, A.K. Buell, T.P.J. Knowles, S. Linse, Nature Chemistry
10 (2018) 523–531.
date_created: 2021-11-26T12:41:38Z
date_published: 2018-03-26T00:00:00Z
date_updated: 2021-11-26T15:14:00Z
day: '26'
doi: 10.1038/s41557-018-0023-x
extern: '1'
external_id:
pmid:
- '29581486'
intvolume: ' 10'
issue: '5'
keyword:
- general chemical engineering
- general chemistry
language:
- iso: eng
month: '03'
oa_version: None
page: 523-531
pmid: 1
publication: Nature Chemistry
publication_identifier:
eissn:
- 1755-4349
issn:
- 1755-4330
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Distinct thermodynamic signatures of oligomer generation in the aggregation
of the amyloid-β peptide
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 10
year: '2018'
...
---
_id: '10361'
abstract:
- lang: eng
text: Understanding how normally soluble peptides and proteins aggregate to form
amyloid fibrils is central to many areas of modern biomolecular science, ranging
from the development of functional biomaterials to the design of rational therapeutic
strategies against increasingly prevalent medical conditions such as Alzheimer's
and Parkinson's diseases. As such, there is a great need to develop models to
mechanistically describe how amyloid fibrils are formed from precursor peptides
and proteins. Here we review and discuss how ideas and concepts from chemical
reaction kinetics can help to achieve this objective. In particular, we show how
a combination of theory, experiments, and computer simulations, based on chemical
kinetics, provides a general formalism for uncovering, at the molecular level,
the mechanistic steps that underlie the phenomenon of amyloid fibril formation.
acknowledgement: "We acknowledge support from the Swiss National Science Foundation
(T.C.T.M.); Peterhouse,\r\nCambridge (T.C.T.M.); the Royal Society (A.S.); the Academy
of Medical Sciences (A.S.); the\r\nWellcome Trust (A.S., M.V., C.M.D., T.P.J.K.);
the Cambridge Centre for Misfolding Diseases\r\n(M.V., C.M.D., T.P.J.K.); the Biotechnology
and Biological Sciences Research Council (C.M.D.,\r\nT.P.J.K.); and the Frances
and Augustus Newman Foundation (T.P.J.K.). The research leading\r\nto these results
has received funding from the European Research Council (ERC) under the\r\nEuropean
Union’s Seventh Framework Programme (FP7/2007-2013) through the ERC grant\r\nPhysProt
(337969)."
article_processing_charge: No
article_type: original
author:
- first_name: Thomas C.T.
full_name: Michaels, Thomas C.T.
last_name: Michaels
- first_name: Anđela
full_name: Šarić, Anđela
id: bf63d406-f056-11eb-b41d-f263a6566d8b
last_name: Šarić
orcid: 0000-0002-7854-2139
- first_name: Johnny
full_name: Habchi, Johnny
last_name: Habchi
- first_name: Sean
full_name: Chia, Sean
last_name: Chia
- first_name: Georg
full_name: Meisl, Georg
last_name: Meisl
- first_name: Michele
full_name: Vendruscolo, Michele
last_name: Vendruscolo
- first_name: Christopher M.
full_name: Dobson, Christopher M.
last_name: Dobson
- first_name: Tuomas P.J.
full_name: Knowles, Tuomas P.J.
last_name: Knowles
citation:
ama: Michaels TCT, Šarić A, Habchi J, et al. Chemical kinetics for bridging molecular
mechanisms and macroscopic measurements of amyloid fibril formation. Annual
Review of Physical Chemistry. 2018;69(1):273-298. doi:10.1146/annurev-physchem-050317-021322
apa: Michaels, T. C. T., Šarić, A., Habchi, J., Chia, S., Meisl, G., Vendruscolo,
M., … Knowles, T. P. J. (2018). Chemical kinetics for bridging molecular mechanisms
and macroscopic measurements of amyloid fibril formation. Annual Review of
Physical Chemistry. Annual Reviews. https://doi.org/10.1146/annurev-physchem-050317-021322
chicago: Michaels, Thomas C.T., Anđela Šarić, Johnny Habchi, Sean Chia, Georg Meisl,
Michele Vendruscolo, Christopher M. Dobson, and Tuomas P.J. Knowles. “Chemical
Kinetics for Bridging Molecular Mechanisms and Macroscopic Measurements of Amyloid
Fibril Formation.” Annual Review of Physical Chemistry. Annual Reviews,
2018. https://doi.org/10.1146/annurev-physchem-050317-021322.
ieee: T. C. T. Michaels et al., “Chemical kinetics for bridging molecular
mechanisms and macroscopic measurements of amyloid fibril formation,” Annual
Review of Physical Chemistry, vol. 69, no. 1. Annual Reviews, pp. 273–298,
2018.
ista: Michaels TCT, Šarić A, Habchi J, Chia S, Meisl G, Vendruscolo M, Dobson CM,
Knowles TPJ. 2018. Chemical kinetics for bridging molecular mechanisms and macroscopic
measurements of amyloid fibril formation. Annual Review of Physical Chemistry.
69(1), 273–298.
mla: Michaels, Thomas C. T., et al. “Chemical Kinetics for Bridging Molecular Mechanisms
and Macroscopic Measurements of Amyloid Fibril Formation.” Annual Review of
Physical Chemistry, vol. 69, no. 1, Annual Reviews, 2018, pp. 273–98, doi:10.1146/annurev-physchem-050317-021322.
short: T.C.T. Michaels, A. Šarić, J. Habchi, S. Chia, G. Meisl, M. Vendruscolo,
C.M. Dobson, T.P.J. Knowles, Annual Review of Physical Chemistry 69 (2018) 273–298.
date_created: 2021-11-26T12:52:12Z
date_published: 2018-02-28T00:00:00Z
date_updated: 2021-11-26T15:58:19Z
day: '28'
doi: 10.1146/annurev-physchem-050317-021322
extern: '1'
external_id:
pmid:
- '29490200'
intvolume: ' 69'
issue: '1'
keyword:
- physical and theoretical chemistry
language:
- iso: eng
month: '02'
oa_version: None
page: 273-298
pmid: 1
publication: Annual Review of Physical Chemistry
publication_identifier:
eissn:
- 1545-1593
issn:
- 0066-426X
publication_status: published
publisher: Annual Reviews
quality_controlled: '1'
scopus_import: '1'
status: public
title: Chemical kinetics for bridging molecular mechanisms and macroscopic measurements
of amyloid fibril formation
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 69
year: '2018'
...
---
_id: '10362'
abstract:
- lang: eng
text: Nuclear pore complexes (NPCs) form gateways that control molecular exchange
between the nucleus and the cytoplasm. They impose a diffusion barrier to macromolecules
and enable the selective transport of nuclear transport receptors with bound cargo.
The underlying mechanisms that establish these permeability properties remain
to be fully elucidated but require unstructured nuclear pore proteins rich in
Phe-Gly (FG)-repeat domains of different types, such as FxFG and GLFG. While physical
modeling and in vitro approaches have provided a framework for explaining how
the FG network contributes to the barrier and transport properties of the NPC,
it remains unknown whether the number and/or the spatial positioning of different
FG-domains along a cylindrical, ∼40 nm diameter transport channel contributes
to their collective properties and function. To begin to answer these questions,
we have used DNA origami to build a cylinder that mimics the dimensions of the
central transport channel and can house a specified number of FG-domains at specific
positions with easily tunable design parameters, such as grafting density and
topology. We find the overall morphology of the FG-domain assemblies to be dependent
on their chemical composition, determined by the type and density of FG-repeat,
and on their architectural confinement provided by the DNA cylinder, largely consistent
with here presented molecular dynamics simulations based on a coarse-grained polymer
model. In addition, high-speed atomic force microscopy reveals local and reversible
FG-domain condensation that transiently occludes the lumen of the DNA central
channel mimics, suggestive of how the NPC might establish its permeability properties.
acknowledgement: We thank J. Edel and members of the Lusk, Lin and Hoogenboom lab
for discussion and acknowledge A. Pyne and R. Thorogate for support carrying out
the AFM experiments. This work was funded by the NIH (R21GM109466 to CPL, CL and
TJM, DP2GM114830 to CL, RO1GM105672 to CPL, and T32GM007223 to PDEF) and the UK
Engineering and Physical Sciences Research Council (EP/L015277/1, EP/L504889/1,
and EP/M028100/1).
article_processing_charge: No
article_type: original
author:
- first_name: Patrick D. Ellis
full_name: Fisher, Patrick D. Ellis
last_name: Fisher
- first_name: Qi
full_name: Shen, Qi
last_name: Shen
- first_name: Bernice
full_name: Akpinar, Bernice
last_name: Akpinar
- first_name: Luke K.
full_name: Davis, Luke K.
last_name: Davis
- first_name: Kenny Kwok Hin
full_name: Chung, Kenny Kwok Hin
last_name: Chung
- first_name: David
full_name: Baddeley, David
last_name: Baddeley
- first_name: Anđela
full_name: Šarić, Anđela
id: bf63d406-f056-11eb-b41d-f263a6566d8b
last_name: Šarić
orcid: 0000-0002-7854-2139
- first_name: Thomas J.
full_name: Melia, Thomas J.
last_name: Melia
- first_name: Bart W.
full_name: Hoogenboom, Bart W.
last_name: Hoogenboom
- first_name: Chenxiang
full_name: Lin, Chenxiang
last_name: Lin
- first_name: C. Patrick
full_name: Lusk, C. Patrick
last_name: Lusk
citation:
ama: Fisher PDE, Shen Q, Akpinar B, et al. A Programmable DNA origami platform for
organizing intrinsically disordered nucleoporins within nanopore confinement.
ACS Nano. 2018;12(2):1508-1518. doi:10.1021/acsnano.7b08044
apa: Fisher, P. D. E., Shen, Q., Akpinar, B., Davis, L. K., Chung, K. K. H., Baddeley,
D., … Lusk, C. P. (2018). A Programmable DNA origami platform for organizing intrinsically
disordered nucleoporins within nanopore confinement. ACS Nano. American
Chemical Society. https://doi.org/10.1021/acsnano.7b08044
chicago: Fisher, Patrick D. Ellis, Qi Shen, Bernice Akpinar, Luke K. Davis, Kenny
Kwok Hin Chung, David Baddeley, Anđela Šarić, et al. “A Programmable DNA Origami
Platform for Organizing Intrinsically Disordered Nucleoporins within Nanopore
Confinement.” ACS Nano. American Chemical Society, 2018. https://doi.org/10.1021/acsnano.7b08044.
ieee: P. D. E. Fisher et al., “A Programmable DNA origami platform for organizing
intrinsically disordered nucleoporins within nanopore confinement,” ACS Nano,
vol. 12, no. 2. American Chemical Society, pp. 1508–1518, 2018.
ista: Fisher PDE, Shen Q, Akpinar B, Davis LK, Chung KKH, Baddeley D, Šarić A, Melia
TJ, Hoogenboom BW, Lin C, Lusk CP. 2018. A Programmable DNA origami platform for
organizing intrinsically disordered nucleoporins within nanopore confinement.
ACS Nano. 12(2), 1508–1518.
mla: Fisher, Patrick D. Ellis, et al. “A Programmable DNA Origami Platform for Organizing
Intrinsically Disordered Nucleoporins within Nanopore Confinement.” ACS Nano,
vol. 12, no. 2, American Chemical Society, 2018, pp. 1508–18, doi:10.1021/acsnano.7b08044.
short: P.D.E. Fisher, Q. Shen, B. Akpinar, L.K. Davis, K.K.H. Chung, D. Baddeley,
A. Šarić, T.J. Melia, B.W. Hoogenboom, C. Lin, C.P. Lusk, ACS Nano 12 (2018) 1508–1518.
date_created: 2021-11-26T15:15:00Z
date_published: 2018-01-19T00:00:00Z
date_updated: 2021-11-26T15:57:02Z
day: '19'
doi: 10.1021/acsnano.7b08044
extern: '1'
external_id:
pmid:
- '29350911'
intvolume: ' 12'
issue: '2'
keyword:
- general physics and astronomy
language:
- iso: eng
month: '01'
oa_version: None
page: 1508-1518
pmid: 1
publication: ACS Nano
publication_identifier:
eissn:
- 1936-086X
issn:
- 1936-0851
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: A Programmable DNA origami platform for organizing intrinsically disordered
nucleoporins within nanopore confinement
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 12
year: '2018'
...
---
_id: '104'
abstract:
- lang: eng
text: The biotrophic pathogen Ustilago maydis, the causative agent of corn smut
disease, infects one of the most important crops worldwide – Zea mays. To successfully
colonize its host, U. maydis secretes proteins, known as effectors, that suppress
plant defense responses and facilitate the establishment of biotrophy. In this
work, we describe the U. maydis effector protein Cce1. Cce1 is essential for virulence
and is upregulated during infection. Through microscopic analysis and in vitro
assays, we show that Cce1 is secreted from hyphae during filamentous growth of
the fungus. Strikingly, Δcce1 mutants are blocked at early stages of infection
and induce callose deposition as a plant defense response. Cce1 is highly conserved
among smut fungi and the Ustilago bromivora ortholog complemented the virulence
defect of the SG200Δcce1 deletion strain. These data indicate that Cce1 is a core
effector with apoplastic localization that is essential for U. maydis to infect
its host.
acknowledgement: 'the Austrian Science Fund (FWF): [P27429‐B22, P27818‐B22, I 3033‐B22],
and the Austrian Academy of Science (OEAW).'
article_processing_charge: No
author:
- first_name: Denise
full_name: Seitner, Denise
last_name: Seitner
- first_name: Simon
full_name: Uhse, Simon
last_name: Uhse
- first_name: Michelle C
full_name: Gallei, Michelle C
id: 35A03822-F248-11E8-B48F-1D18A9856A87
last_name: Gallei
orcid: 0000-0003-1286-7368
- first_name: Armin
full_name: Djamei, Armin
last_name: Djamei
citation:
ama: Seitner D, Uhse S, Gallei MC, Djamei A. The core effector Cce1 is required
for early infection of maize by Ustilago maydis. Molecular Plant Pathology.
2018;19(10):2277-2287. doi:10.1111/mpp.12698
apa: Seitner, D., Uhse, S., Gallei, M. C., & Djamei, A. (2018). The core effector
Cce1 is required for early infection of maize by Ustilago maydis. Molecular
Plant Pathology. Wiley. https://doi.org/10.1111/mpp.12698
chicago: Seitner, Denise, Simon Uhse, Michelle C Gallei, and Armin Djamei. “The
Core Effector Cce1 Is Required for Early Infection of Maize by Ustilago Maydis.”
Molecular Plant Pathology. Wiley, 2018. https://doi.org/10.1111/mpp.12698.
ieee: D. Seitner, S. Uhse, M. C. Gallei, and A. Djamei, “The core effector Cce1
is required for early infection of maize by Ustilago maydis,” Molecular Plant
Pathology, vol. 19, no. 10. Wiley, pp. 2277–2287, 2018.
ista: Seitner D, Uhse S, Gallei MC, Djamei A. 2018. The core effector Cce1 is required
for early infection of maize by Ustilago maydis. Molecular Plant Pathology. 19(10),
2277–2287.
mla: Seitner, Denise, et al. “The Core Effector Cce1 Is Required for Early Infection
of Maize by Ustilago Maydis.” Molecular Plant Pathology, vol. 19, no. 10,
Wiley, 2018, pp. 2277–87, doi:10.1111/mpp.12698.
short: D. Seitner, S. Uhse, M.C. Gallei, A. Djamei, Molecular Plant Pathology 19
(2018) 2277–2287.
date_created: 2018-12-11T11:44:39Z
date_published: 2018-10-01T00:00:00Z
date_updated: 2023-09-19T10:06:42Z
day: '01'
ddc:
- '580'
department:
- _id: GradSch
doi: 10.1111/mpp.12698
external_id:
isi:
- '000445624100006'
file:
- access_level: open_access
content_type: application/pdf
creator: dernst
date_created: 2018-12-18T09:46:00Z
date_updated: 2018-12-18T09:46:00Z
file_id: '5740'
file_name: 2018_MolecPlantPath_Seitner.pdf
file_size: 682335
relation: main_file
success: 1
file_date_updated: 2018-12-18T09:46:00Z
has_accepted_license: '1'
intvolume: ' 19'
isi: 1
issue: '10'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
page: 2277 - 2287
publication: Molecular Plant Pathology
publication_status: published
publisher: Wiley
publist_id: '7950'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The core effector Cce1 is required for early infection of maize by Ustilago
maydis
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 19
year: '2018'
...
---
OA_place: publisher
OA_type: hybrid
_id: '10417'
abstract:
- lang: eng
text: "We present a new dynamic partial-order reduction method for stateless model
checking of concurrent programs. A common approach for exploring program behaviors
relies on enumerating the traces of the program, without storing the visited states
(aka stateless exploration). As the number of distinct traces grows exponentially,
dynamic partial-order reduction (DPOR) techniques have been successfully used
to partition the space of traces into equivalence classes (Mazurkiewicz partitioning),
with the goal of exploring only few representative traces from each class.\r\n\r\nWe
introduce a new equivalence on traces under sequential consistency semantics,
which we call the observation equivalence. Two traces are observationally equivalent
if every read event observes the same write event in both traces. While the traditional
Mazurkiewicz equivalence is control-centric, our new definition is data-centric.
We show that our observation equivalence is coarser than the Mazurkiewicz equivalence,
and in many cases even exponentially coarser. We devise a DPOR exploration of
the trace space, called data-centric DPOR, based on the observation equivalence."
acknowledgement: "The research was partly supported by Austrian Science Fund (FWF)
Grant No P23499- N23, FWF\r\nNFN Grant No S11407-N23 (RiSE/SHiNE), ERC Start grant
(279307: Graph Games), and Czech\r\nScience Foundation grant GBP202/12/G061."
article_number: '31'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Marek
full_name: Chalupa, Marek
last_name: Chalupa
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Andreas
full_name: Pavlogiannis, Andreas
id: 49704004-F248-11E8-B48F-1D18A9856A87
last_name: Pavlogiannis
orcid: 0000-0002-8943-0722
- first_name: Nishant
full_name: Sinha, Nishant
last_name: Sinha
- first_name: Kapil
full_name: Vaidya, Kapil
last_name: Vaidya
citation:
ama: Chalupa M, Chatterjee K, Pavlogiannis A, Sinha N, Vaidya K. Data-centric dynamic
partial order reduction. Proceedings of the ACM on Programming Languages.
2018;2(POPL). doi:10.1145/3158119
apa: 'Chalupa, M., Chatterjee, K., Pavlogiannis, A., Sinha, N., & Vaidya, K.
(2018). Data-centric dynamic partial order reduction. Proceedings of the ACM
on Programming Languages. Los Angeles, CA, United States: Association for
Computing Machinery. https://doi.org/10.1145/3158119'
chicago: Chalupa, Marek, Krishnendu Chatterjee, Andreas Pavlogiannis, Nishant Sinha,
and Kapil Vaidya. “Data-Centric Dynamic Partial Order Reduction.” Proceedings
of the ACM on Programming Languages. Association for Computing Machinery,
2018. https://doi.org/10.1145/3158119.
ieee: M. Chalupa, K. Chatterjee, A. Pavlogiannis, N. Sinha, and K. Vaidya, “Data-centric
dynamic partial order reduction,” Proceedings of the ACM on Programming Languages,
vol. 2, no. POPL. Association for Computing Machinery, 2018.
ista: Chalupa M, Chatterjee K, Pavlogiannis A, Sinha N, Vaidya K. 2018. Data-centric
dynamic partial order reduction. Proceedings of the ACM on Programming Languages.
2(POPL), 31.
mla: Chalupa, Marek, et al. “Data-Centric Dynamic Partial Order Reduction.” Proceedings
of the ACM on Programming Languages, vol. 2, no. POPL, 31, Association for
Computing Machinery, 2018, doi:10.1145/3158119.
short: M. Chalupa, K. Chatterjee, A. Pavlogiannis, N. Sinha, K. Vaidya, Proceedings
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