---
_id: '14310'
article_processing_charge: No
author:
- first_name: Mahsa
  full_name: Siavashpouri, Mahsa
  last_name: Siavashpouri
- first_name: Christian
  full_name: Wachauf, Christian
  last_name: Wachauf
- first_name: Mark
  full_name: Zakhary, Mark
  last_name: Zakhary
- first_name: Florian M
  full_name: Praetorius, Florian M
  id: dfec9381-4341-11ee-8fd8-faa02bba7d62
  last_name: Praetorius
- first_name: Hendrik
  full_name: Dietz, Hendrik
  last_name: Dietz
- first_name: Zvonimir
  full_name: Dogic, Zvonimir
  last_name: Dogic
citation:
  ama: 'Siavashpouri M, Wachauf C, Zakhary M, Praetorius FM, Dietz H, Dogic Z. Molecular
    engineering of colloidal liquid crystals using DNA origami. In: <i>APS March Meeting
    2017</i>. APS; 2017.'
  apa: Siavashpouri, M., Wachauf, C., Zakhary, M., Praetorius, F. M., Dietz, H., &#38;
    Dogic, Z. (2017). Molecular engineering of colloidal liquid crystals using DNA
    origami. In <i>APS March Meeting 2017</i>. APS.
  chicago: Siavashpouri, Mahsa, Christian Wachauf, Mark Zakhary, Florian M Praetorius,
    Hendrik Dietz, and Zvonimir Dogic. “Molecular Engineering of Colloidal Liquid
    Crystals Using DNA Origami.” In <i>APS March Meeting 2017</i>. APS, 2017.
  ieee: M. Siavashpouri, C. Wachauf, M. Zakhary, F. M. Praetorius, H. Dietz, and Z.
    Dogic, “Molecular engineering of colloidal liquid crystals using DNA origami,”
    in <i>APS March Meeting 2017</i>, 2017.
  ista: Siavashpouri M, Wachauf C, Zakhary M, Praetorius FM, Dietz H, Dogic Z. 2017.
    Molecular engineering of colloidal liquid crystals using DNA origami. APS March
    Meeting 2017. .
  mla: Siavashpouri, Mahsa, et al. “Molecular Engineering of Colloidal Liquid Crystals
    Using DNA Origami.” <i>APS March Meeting 2017</i>, APS, 2017.
  short: M. Siavashpouri, C. Wachauf, M. Zakhary, F.M. Praetorius, H. Dietz, Z. Dogic,
    in:, APS March Meeting 2017, APS, 2017.
date_created: 2023-09-06T13:40:20Z
date_published: 2017-03-01T00:00:00Z
date_updated: 2023-11-07T11:36:15Z
day: '01'
extern: '1'
language:
- iso: eng
month: '03'
oa_version: None
publication: APS March Meeting 2017
publication_status: published
publisher: APS
quality_controlled: '1'
status: public
title: Molecular engineering of colloidal liquid crystals using DNA origami
type: conference_abstract
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2017'
...
---
OA_type: free access
_id: '1433'
abstract:
- lang: eng
  text: Phat is an open-source C. ++ library for the computation of persistent homology
    by matrix reduction, targeted towards developers of software for topological data
    analysis. We aim for a simple generic design that decouples algorithms from data
    structures without sacrificing efficiency or user-friendliness. We provide numerous
    different reduction strategies as well as data types to store and manipulate the
    boundary matrix. We compare the different combinations through extensive experimental
    evaluation and identify optimization techniques that work well in practical situations.
    We also compare our software with various other publicly available libraries for
    persistent homology.
acknowledgement: Michael Kerber acknowledges support by the Max Planck Center for
  Visual Computing and Communications (FKZ-01IMC01 and FKZ-01IM10001). Ulrich Bauer,
  Jan Reininghaus, and Hubert Wagner acknowledge support by the EU Project TOPOSYS
  (FP7-ICT-318493-STREP).
article_processing_charge: No
article_type: original
author:
- first_name: Ulrich
  full_name: Bauer, Ulrich
  last_name: Bauer
- first_name: Michael
  full_name: Kerber, Michael
  last_name: Kerber
- first_name: Jan
  full_name: Reininghaus, Jan
  last_name: Reininghaus
- first_name: Hubert
  full_name: Wagner, Hubert
  id: 379CA8B8-F248-11E8-B48F-1D18A9856A87
  last_name: Wagner
  orcid: 0009-0009-9111-8429
citation:
  ama: Bauer U, Kerber M, Reininghaus J, Wagner H. Phat - Persistent homology algorithms
    toolbox. <i>Journal of Symbolic Computation</i>. 2017;78:76-90. doi:<a href="https://doi.org/10.1016/j.jsc.2016.03.008">10.1016/j.jsc.2016.03.008</a>
  apa: Bauer, U., Kerber, M., Reininghaus, J., &#38; Wagner, H. (2017). Phat - Persistent
    homology algorithms toolbox. <i>Journal of Symbolic Computation</i>. Academic
    Press. <a href="https://doi.org/10.1016/j.jsc.2016.03.008">https://doi.org/10.1016/j.jsc.2016.03.008</a>
  chicago: Bauer, Ulrich, Michael Kerber, Jan Reininghaus, and Hubert Wagner. “Phat
    - Persistent Homology Algorithms Toolbox.” <i>Journal of Symbolic Computation</i>.
    Academic Press, 2017. <a href="https://doi.org/10.1016/j.jsc.2016.03.008">https://doi.org/10.1016/j.jsc.2016.03.008</a>.
  ieee: U. Bauer, M. Kerber, J. Reininghaus, and H. Wagner, “Phat - Persistent homology
    algorithms toolbox,” <i>Journal of Symbolic Computation</i>, vol. 78. Academic
    Press, pp. 76–90, 2017.
  ista: Bauer U, Kerber M, Reininghaus J, Wagner H. 2017. Phat - Persistent homology
    algorithms toolbox. Journal of Symbolic Computation. 78, 76–90.
  mla: Bauer, Ulrich, et al. “Phat - Persistent Homology Algorithms Toolbox.” <i>Journal
    of Symbolic Computation</i>, vol. 78, Academic Press, 2017, pp. 76–90, doi:<a
    href="https://doi.org/10.1016/j.jsc.2016.03.008">10.1016/j.jsc.2016.03.008</a>.
  short: U. Bauer, M. Kerber, J. Reininghaus, H. Wagner, Journal of Symbolic Computation
    78 (2017) 76–90.
corr_author: '1'
date_created: 2018-12-11T11:51:59Z
date_published: 2017-01-01T00:00:00Z
date_updated: 2026-06-18T17:35:16Z
day: '01'
ddc:
- '500'
department:
- _id: HeEd
doi: 10.1016/j.jsc.2016.03.008
ec_funded: 1
external_id:
  isi:
  - '000384396000005'
intvolume: '        78'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.jsc.2016.03.008
month: '01'
oa: 1
oa_version: Published Version
page: 76 - 90
project:
- _id: 255D761E-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '318493'
  name: Topological Complex Systems
publication: Journal of Symbolic Computation
publication_identifier:
  issn:
  - ' 0747-7171'
publication_status: published
publisher: Academic Press
publist_id: '5765'
quality_controlled: '1'
related_material:
  record:
  - id: '10894'
    relation: earlier_version
    status: public
scopus_import: '1'
status: public
title: Phat - Persistent homology algorithms toolbox
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 78
year: '2017'
...
---
_id: '15154'
abstract:
- lang: eng
  text: Biofilm formation is critical for the infection cycle of Vibrio cholerae.
    Vibrio exopolysaccharides (VPS) and the matrix proteins RbmA, Bap1 and RbmC are
    required for the development of biofilm architecture. We demonstrate that RbmA
    binds VPS directly and uses a binary structural switch within its first fibronectin
    type III (FnIII-1) domain to control RbmA structural dynamics and the formation
    of VPS-dependent higher-order structures. The structural switch in FnIII-1 regulates
    interactions in trans with the FnIII-2 domain, leading to open (monomeric) or
    closed (dimeric) interfaces. The ability of RbmA to switch between open and closed
    states is important for V. cholerae biofilm formation, as RbmA variants with switches
    that are locked in either of the two states lead to biofilms with altered architecture
    and structural integrity.
article_number: '26163'
article_processing_charge: Yes
article_type: original
author:
- first_name: Jiunn CN
  full_name: Fong, Jiunn CN
  last_name: Fong
- first_name: Andrew
  full_name: Rogers, Andrew
  last_name: Rogers
- first_name: Alicia Kathleen
  full_name: Michael, Alicia Kathleen
  id: 6437c950-2a03-11ee-914d-d6476dd7b75c
  last_name: Michael
- first_name: Nicole C
  full_name: Parsley, Nicole C
  last_name: Parsley
- first_name: William-Cole
  full_name: Cornell, William-Cole
  last_name: Cornell
- first_name: Yu-Cheng
  full_name: Lin, Yu-Cheng
  last_name: Lin
- first_name: Praveen K
  full_name: Singh, Praveen K
  last_name: Singh
- first_name: Raimo
  full_name: Hartmann, Raimo
  last_name: Hartmann
- first_name: Knut
  full_name: Drescher, Knut
  last_name: Drescher
- first_name: Evgeny
  full_name: Vinogradov, Evgeny
  last_name: Vinogradov
- first_name: Lars EP
  full_name: Dietrich, Lars EP
  last_name: Dietrich
- first_name: Carrie L
  full_name: Partch, Carrie L
  last_name: Partch
- first_name: Fitnat H
  full_name: Yildiz, Fitnat H
  last_name: Yildiz
citation:
  ama: Fong JC, Rogers A, Michael AK, et al. Structural dynamics of RbmA governs plasticity
    of Vibrio cholerae biofilms. <i>eLife</i>. 2017;6. doi:<a href="https://doi.org/10.7554/elife.26163">10.7554/elife.26163</a>
  apa: Fong, J. C., Rogers, A., Michael, A. K., Parsley, N. C., Cornell, W.-C., Lin,
    Y.-C., … Yildiz, F. H. (2017). Structural dynamics of RbmA governs plasticity
    of Vibrio cholerae biofilms. <i>ELife</i>. eLife Sciences Publications. <a href="https://doi.org/10.7554/elife.26163">https://doi.org/10.7554/elife.26163</a>
  chicago: Fong, Jiunn CN, Andrew Rogers, Alicia K. Michael, Nicole C Parsley, William-Cole
    Cornell, Yu-Cheng Lin, Praveen K Singh, et al. “Structural Dynamics of RbmA Governs
    Plasticity of Vibrio Cholerae Biofilms.” <i>ELife</i>. eLife Sciences Publications,
    2017. <a href="https://doi.org/10.7554/elife.26163">https://doi.org/10.7554/elife.26163</a>.
  ieee: J. C. Fong <i>et al.</i>, “Structural dynamics of RbmA governs plasticity
    of Vibrio cholerae biofilms,” <i>eLife</i>, vol. 6. eLife Sciences Publications,
    2017.
  ista: Fong JC, Rogers A, Michael AK, Parsley NC, Cornell W-C, Lin Y-C, Singh PK,
    Hartmann R, Drescher K, Vinogradov E, Dietrich LE, Partch CL, Yildiz FH. 2017.
    Structural dynamics of RbmA governs plasticity of Vibrio cholerae biofilms. eLife.
    6, 26163.
  mla: Fong, Jiunn CN, et al. “Structural Dynamics of RbmA Governs Plasticity of Vibrio
    Cholerae Biofilms.” <i>ELife</i>, vol. 6, 26163, eLife Sciences Publications,
    2017, doi:<a href="https://doi.org/10.7554/elife.26163">10.7554/elife.26163</a>.
  short: J.C. Fong, A. Rogers, A.K. Michael, N.C. Parsley, W.-C. Cornell, Y.-C. Lin,
    P.K. Singh, R. Hartmann, K. Drescher, E. Vinogradov, L.E. Dietrich, C.L. Partch,
    F.H. Yildiz, ELife 6 (2017).
date_created: 2024-03-21T07:55:36Z
date_published: 2017-08-01T00:00:00Z
date_updated: 2024-03-25T12:22:54Z
day: '01'
doi: 10.7554/elife.26163
extern: '1'
external_id:
  pmid:
  - '28762945'
intvolume: '         6'
keyword:
- General Immunology and Microbiology
- General Biochemistry
- Genetics and Molecular Biology
- General Medicine
- General Neuroscience
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.7554/eLife.26163
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
publication: eLife
publication_identifier:
  issn:
  - 2050-084X
publication_status: published
publisher: eLife Sciences Publications
quality_controlled: '1'
scopus_import: '1'
status: public
title: Structural dynamics of RbmA governs plasticity of Vibrio cholerae biofilms
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2017'
...
---
_id: '15155'
abstract:
- lang: eng
  text: The C-terminal transactivation domain (TAD) of BMAL1 (brain and muscle ARNT-like
    1) is a regulatory hub for transcriptional coactivators and repressors that compete
    for binding and, consequently, contributes to period determination of the mammalian
    circadian clock. Here, we report the discovery of two distinct conformational
    states that slowly exchange within the dynamic TAD to control timing. This binary
    switch results from cis/trans isomerization about a highly conserved Trp-Pro imide
    bond in a region of the TAD that is required for normal circadian timekeeping.
    Both cis and trans isomers interact with transcriptional regulators, suggesting
    that isomerization could serve a role in assembling regulatory complexes in vivo.
    Toward this end, we show that locking the switch into the trans isomer leads to
    shortened circadian periods. Furthermore, isomerization is regulated by the cyclophilin
    family of peptidyl-prolyl isomerases, highlighting the potential for regulation
    of BMAL1 protein dynamics in period determination.
article_processing_charge: No
article_type: original
author:
- first_name: Chelsea L.
  full_name: Gustafson, Chelsea L.
  last_name: Gustafson
- first_name: Nicole C.
  full_name: Parsley, Nicole C.
  last_name: Parsley
- first_name: Hande
  full_name: Asimgil, Hande
  last_name: Asimgil
- first_name: Hsiau-Wei
  full_name: Lee, Hsiau-Wei
  last_name: Lee
- first_name: Christopher
  full_name: Ahlbach, Christopher
  last_name: Ahlbach
- first_name: Alicia Kathleen
  full_name: Michael, Alicia Kathleen
  id: 6437c950-2a03-11ee-914d-d6476dd7b75c
  last_name: Michael
- first_name: Haiyan
  full_name: Xu, Haiyan
  last_name: Xu
- first_name: Owen L.
  full_name: Williams, Owen L.
  last_name: Williams
- first_name: Tara L.
  full_name: Davis, Tara L.
  last_name: Davis
- first_name: Andrew C.
  full_name: Liu, Andrew C.
  last_name: Liu
- first_name: Carrie L.
  full_name: Partch, Carrie L.
  last_name: Partch
citation:
  ama: Gustafson CL, Parsley NC, Asimgil H, et al. A slow conformational switch in
    the BMAL1 transactivation domain modulates circadian rhythms. <i>Molecular Cell</i>.
    2017;66(4):447-457.e7. doi:<a href="https://doi.org/10.1016/j.molcel.2017.04.011">10.1016/j.molcel.2017.04.011</a>
  apa: Gustafson, C. L., Parsley, N. C., Asimgil, H., Lee, H.-W., Ahlbach, C., Michael,
    A. K., … Partch, C. L. (2017). A slow conformational switch in the BMAL1 transactivation
    domain modulates circadian rhythms. <i>Molecular Cell</i>. Elsevier. <a href="https://doi.org/10.1016/j.molcel.2017.04.011">https://doi.org/10.1016/j.molcel.2017.04.011</a>
  chicago: Gustafson, Chelsea L., Nicole C. Parsley, Hande Asimgil, Hsiau-Wei Lee,
    Christopher Ahlbach, Alicia K. Michael, Haiyan Xu, et al. “A Slow Conformational
    Switch in the BMAL1 Transactivation Domain Modulates Circadian Rhythms.” <i>Molecular
    Cell</i>. Elsevier, 2017. <a href="https://doi.org/10.1016/j.molcel.2017.04.011">https://doi.org/10.1016/j.molcel.2017.04.011</a>.
  ieee: C. L. Gustafson <i>et al.</i>, “A slow conformational switch in the BMAL1
    transactivation domain modulates circadian rhythms,” <i>Molecular Cell</i>, vol.
    66, no. 4. Elsevier, p. 447–457.e7, 2017.
  ista: Gustafson CL, Parsley NC, Asimgil H, Lee H-W, Ahlbach C, Michael AK, Xu H,
    Williams OL, Davis TL, Liu AC, Partch CL. 2017. A slow conformational switch in
    the BMAL1 transactivation domain modulates circadian rhythms. Molecular Cell.
    66(4), 447–457.e7.
  mla: Gustafson, Chelsea L., et al. “A Slow Conformational Switch in the BMAL1 Transactivation
    Domain Modulates Circadian Rhythms.” <i>Molecular Cell</i>, vol. 66, no. 4, Elsevier,
    2017, p. 447–457.e7, doi:<a href="https://doi.org/10.1016/j.molcel.2017.04.011">10.1016/j.molcel.2017.04.011</a>.
  short: C.L. Gustafson, N.C. Parsley, H. Asimgil, H.-W. Lee, C. Ahlbach, A.K. Michael,
    H. Xu, O.L. Williams, T.L. Davis, A.C. Liu, C.L. Partch, Molecular Cell 66 (2017)
    447–457.e7.
date_created: 2024-03-21T07:56:01Z
date_published: 2017-05-18T00:00:00Z
date_updated: 2024-03-25T12:19:20Z
day: '18'
doi: 10.1016/j.molcel.2017.04.011
extern: '1'
intvolume: '        66'
issue: '4'
keyword:
- Cell Biology
- Molecular Biology
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.molcel.2017.04.011
month: '05'
oa: 1
oa_version: Published Version
page: 447-457.e7
publication: Molecular Cell
publication_identifier:
  issn:
  - 1097-2765
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: A slow conformational switch in the BMAL1 transactivation domain modulates
  circadian rhythms
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 66
year: '2017'
...
---
_id: '15156'
abstract:
- lang: eng
  text: Circadian clocks are ubiquitous timing systems that induce rhythms of biological
    activities in synchrony with night and day. In cyanobacteria, timing is generated
    by a posttranslational clock consisting of KaiA, KaiB, and KaiC proteins and a
    set of output signaling proteins, SasA and CikA, which transduce this rhythm to
    control gene expression. Here, we describe crystal and nuclear magnetic resonance
    structures of KaiB-KaiC,KaiA-KaiB-KaiC, and CikA-KaiB complexes. They reveal how
    the metamorphic properties of KaiB, a protein that adopts two distinct folds,
    and the post–adenosine triphosphate hydrolysis state of KaiC create a hub around
    which nighttime signaling events revolve, including inactivation of KaiA and reciprocal
    regulation of the mutually antagonistic signaling proteins, SasA and CikA.
article_processing_charge: No
article_type: original
author:
- first_name: Roger
  full_name: Tseng, Roger
  last_name: Tseng
- first_name: Nicolette F.
  full_name: Goularte, Nicolette F.
  last_name: Goularte
- first_name: Archana
  full_name: Chavan, Archana
  last_name: Chavan
- first_name: Jansen
  full_name: Luu, Jansen
  last_name: Luu
- first_name: Susan E.
  full_name: Cohen, Susan E.
  last_name: Cohen
- first_name: Yong-Gang
  full_name: Chang, Yong-Gang
  last_name: Chang
- first_name: Joel
  full_name: Heisler, Joel
  last_name: Heisler
- first_name: Sheng
  full_name: Li, Sheng
  last_name: Li
- first_name: Alicia Kathleen
  full_name: Michael, Alicia Kathleen
  id: 6437c950-2a03-11ee-914d-d6476dd7b75c
  last_name: Michael
- first_name: Sarvind
  full_name: Tripathi, Sarvind
  last_name: Tripathi
- first_name: Susan S.
  full_name: Golden, Susan S.
  last_name: Golden
- first_name: Andy
  full_name: LiWang, Andy
  last_name: LiWang
- first_name: Carrie L.
  full_name: Partch, Carrie L.
  last_name: Partch
citation:
  ama: Tseng R, Goularte NF, Chavan A, et al. Structural basis of the day-night transition
    in a bacterial circadian clock. <i>Science</i>. 2017;355(6330):1174-1180. doi:<a
    href="https://doi.org/10.1126/science.aag2516">10.1126/science.aag2516</a>
  apa: Tseng, R., Goularte, N. F., Chavan, A., Luu, J., Cohen, S. E., Chang, Y.-G.,
    … Partch, C. L. (2017). Structural basis of the day-night transition in a bacterial
    circadian clock. <i>Science</i>. American Association for the Advancement of Science.
    <a href="https://doi.org/10.1126/science.aag2516">https://doi.org/10.1126/science.aag2516</a>
  chicago: Tseng, Roger, Nicolette F. Goularte, Archana Chavan, Jansen Luu, Susan
    E. Cohen, Yong-Gang Chang, Joel Heisler, et al. “Structural Basis of the Day-Night
    Transition in a Bacterial Circadian Clock.” <i>Science</i>. American Association
    for the Advancement of Science, 2017. <a href="https://doi.org/10.1126/science.aag2516">https://doi.org/10.1126/science.aag2516</a>.
  ieee: R. Tseng <i>et al.</i>, “Structural basis of the day-night transition in a
    bacterial circadian clock,” <i>Science</i>, vol. 355, no. 6330. American Association
    for the Advancement of Science, pp. 1174–1180, 2017.
  ista: Tseng R, Goularte NF, Chavan A, Luu J, Cohen SE, Chang Y-G, Heisler J, Li
    S, Michael AK, Tripathi S, Golden SS, LiWang A, Partch CL. 2017. Structural basis
    of the day-night transition in a bacterial circadian clock. Science. 355(6330),
    1174–1180.
  mla: Tseng, Roger, et al. “Structural Basis of the Day-Night Transition in a Bacterial
    Circadian Clock.” <i>Science</i>, vol. 355, no. 6330, American Association for
    the Advancement of Science, 2017, pp. 1174–80, doi:<a href="https://doi.org/10.1126/science.aag2516">10.1126/science.aag2516</a>.
  short: R. Tseng, N.F. Goularte, A. Chavan, J. Luu, S.E. Cohen, Y.-G. Chang, J. Heisler,
    S. Li, A.K. Michael, S. Tripathi, S.S. Golden, A. LiWang, C.L. Partch, Science
    355 (2017) 1174–1180.
date_created: 2024-03-21T07:56:24Z
date_published: 2017-03-17T00:00:00Z
date_updated: 2024-03-25T12:16:44Z
day: '17'
doi: 10.1126/science.aag2516
extern: '1'
intvolume: '       355'
issue: '6330'
keyword:
- Multidisciplinary
language:
- iso: eng
month: '03'
oa_version: None
page: 1174-1180
publication: Science
publication_identifier:
  eissn:
  - 1095-9203
  issn:
  - 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Structural basis of the day-night transition in a bacterial circadian clock
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 355
year: '2017'
...
---
_id: '15157'
abstract:
- lang: eng
  text: The basic helix–loop–helix PAS domain (bHLH-PAS) transcription factor CLOCK:BMAL1
    (brain and muscle Arnt-like protein 1) sits at the core of the mammalian circadian
    transcription/translation feedback loop. Precise control of CLOCK:BMAL1 activity
    by coactivators and repressors establishes the ∼24-h periodicity of gene expression.
    Formation of a repressive complex, defined by the core clock proteins cryptochrome
    1 (CRY1):CLOCK:BMAL1, plays an important role controlling the switch from repression
    to activation each day. Here we show that CRY1 binds directly to the PAS domain
    core of CLOCK:BMAL1, driven primarily by interaction with the CLOCK PAS-B domain.
    Integrative modeling and solution X-ray scattering studies unambiguously position
    a key loop of the CLOCK PAS-B domain in the secondary pocket of CRY1, analogous
    to the antenna chromophore-binding pocket of photolyase. CRY1 docks onto the transcription
    factor alongside the PAS domains, extending above the DNA-binding bHLH domain.
    Single point mutations at the interface on either CRY1 or CLOCK disrupt formation
    of the ternary complex, highlighting the importance of this interface for direct
    regulation of CLOCK:BMAL1 activity by CRY1.
article_processing_charge: No
article_type: original
author:
- first_name: Alicia Kathleen
  full_name: Michael, Alicia Kathleen
  id: 6437c950-2a03-11ee-914d-d6476dd7b75c
  last_name: Michael
- first_name: Jennifer L.
  full_name: Fribourgh, Jennifer L.
  last_name: Fribourgh
- first_name: Yogarany
  full_name: Chelliah, Yogarany
  last_name: Chelliah
- first_name: Colby R.
  full_name: Sandate, Colby R.
  last_name: Sandate
- first_name: Greg L.
  full_name: Hura, Greg L.
  last_name: Hura
- first_name: Dina
  full_name: Schneidman-Duhovny, Dina
  last_name: Schneidman-Duhovny
- first_name: Sarvind M.
  full_name: Tripathi, Sarvind M.
  last_name: Tripathi
- first_name: Joseph S.
  full_name: Takahashi, Joseph S.
  last_name: Takahashi
- first_name: Carrie L.
  full_name: Partch, Carrie L.
  last_name: Partch
citation:
  ama: Michael AK, Fribourgh JL, Chelliah Y, et al. Formation of a repressive complex
    in the mammalian circadian clock is mediated by the secondary pocket of CRY1.
    <i>Proceedings of the National Academy of Sciences</i>. 2017;114(7):1560-1565.
    doi:<a href="https://doi.org/10.1073/pnas.1615310114">10.1073/pnas.1615310114</a>
  apa: Michael, A. K., Fribourgh, J. L., Chelliah, Y., Sandate, C. R., Hura, G. L.,
    Schneidman-Duhovny, D., … Partch, C. L. (2017). Formation of a repressive complex
    in the mammalian circadian clock is mediated by the secondary pocket of CRY1.
    <i>Proceedings of the National Academy of Sciences</i>. Proceedings of the National
    Academy of Sciences. <a href="https://doi.org/10.1073/pnas.1615310114">https://doi.org/10.1073/pnas.1615310114</a>
  chicago: Michael, Alicia K., Jennifer L. Fribourgh, Yogarany Chelliah, Colby R.
    Sandate, Greg L. Hura, Dina Schneidman-Duhovny, Sarvind M. Tripathi, Joseph S.
    Takahashi, and Carrie L. Partch. “Formation of a Repressive Complex in the Mammalian
    Circadian Clock Is Mediated by the Secondary Pocket of CRY1.” <i>Proceedings of
    the National Academy of Sciences</i>. Proceedings of the National Academy of Sciences,
    2017. <a href="https://doi.org/10.1073/pnas.1615310114">https://doi.org/10.1073/pnas.1615310114</a>.
  ieee: A. K. Michael <i>et al.</i>, “Formation of a repressive complex in the mammalian
    circadian clock is mediated by the secondary pocket of CRY1,” <i>Proceedings of
    the National Academy of Sciences</i>, vol. 114, no. 7. Proceedings of the National
    Academy of Sciences, pp. 1560–1565, 2017.
  ista: Michael AK, Fribourgh JL, Chelliah Y, Sandate CR, Hura GL, Schneidman-Duhovny
    D, Tripathi SM, Takahashi JS, Partch CL. 2017. Formation of a repressive complex
    in the mammalian circadian clock is mediated by the secondary pocket of CRY1.
    Proceedings of the National Academy of Sciences. 114(7), 1560–1565.
  mla: Michael, Alicia K., et al. “Formation of a Repressive Complex in the Mammalian
    Circadian Clock Is Mediated by the Secondary Pocket of CRY1.” <i>Proceedings of
    the National Academy of Sciences</i>, vol. 114, no. 7, Proceedings of the National
    Academy of Sciences, 2017, pp. 1560–65, doi:<a href="https://doi.org/10.1073/pnas.1615310114">10.1073/pnas.1615310114</a>.
  short: A.K. Michael, J.L. Fribourgh, Y. Chelliah, C.R. Sandate, G.L. Hura, D. Schneidman-Duhovny,
    S.M. Tripathi, J.S. Takahashi, C.L. Partch, Proceedings of the National Academy
    of Sciences 114 (2017) 1560–1565.
date_created: 2024-03-21T07:56:50Z
date_published: 2017-01-31T00:00:00Z
date_updated: 2024-03-25T12:12:23Z
day: '31'
doi: 10.1073/pnas.1615310114
extern: '1'
external_id:
  pmid:
  - '28143926'
intvolume: '       114'
issue: '7'
keyword:
- Multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1073/pnas.1615310114
month: '01'
oa: 1
oa_version: Published Version
page: 1560-1565
pmid: 1
publication: Proceedings of the National Academy of Sciences
publication_identifier:
  eissn:
  - 1091-6490
  issn:
  - 0027-8424
publication_status: published
publisher: Proceedings of the National Academy of Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Formation of a repressive complex in the mammalian circadian clock is mediated
  by the secondary pocket of CRY1
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 114
year: '2017'
...
---
_id: '15158'
abstract:
- lang: eng
  text: 'Cryptochromes are evolutionarily related to the light‐dependent DNA repair
    enzyme photolyase, serving as major regulators of circadian rhythms in insects
    and vertebrate animals. There are two types of cryptochromes in the animal kingdom:
    <jats:italic>Drosophila</jats:italic>‐like CRYs that act as nonvisual photopigments
    linking circadian rhythms to the environmental light/dark cycle, and vertebrate‐like
    CRYs that do not appear to sense light directly, but control the generation of
    circadian rhythms by acting as transcriptional repressors. Some animals have both
    types of CRYs, while others possess only one. Cryptochromes have two domains,
    the photolyase homology region (PHR) and an extended, intrinsically disordered
    C‐terminus. While all animal CRYs share a high degree of sequence and structural
    homology in their PHR domains, the C‐termini are divergent in both length and
    sequence identity. Recently, cryptochrome function has been shown to extend beyond
    its pivotal role in circadian clocks, participating in regulation of the DNA damage
    response, cancer progression and glucocorticoid signaling, as well as being implicated
    as possible magnetoreceptors. In this review, we provide a historical perspective
    on the discovery of animal cryptochromes, examine similarities and differences
    of the two types of animal cryptochromes and explore some of the divergent roles
    for this class of proteins.'
article_processing_charge: No
article_type: original
author:
- first_name: Alicia Kathleen
  full_name: Michael, Alicia Kathleen
  id: 6437c950-2a03-11ee-914d-d6476dd7b75c
  last_name: Michael
- first_name: Jennifer L.
  full_name: Fribourgh, Jennifer L.
  last_name: Fribourgh
- first_name: Russell N.
  full_name: Van Gelder, Russell N.
  last_name: Van Gelder
- first_name: Carrie L.
  full_name: Partch, Carrie L.
  last_name: Partch
citation:
  ama: 'Michael AK, Fribourgh JL, Van Gelder RN, Partch CL. Animal cryptochromes:
    Divergent roles in light perception, circadian timekeeping and beyond. <i>Photochemistry
    and Photobiology</i>. 2017;93(1):128-140. doi:<a href="https://doi.org/10.1111/php.12677">10.1111/php.12677</a>'
  apa: 'Michael, A. K., Fribourgh, J. L., Van Gelder, R. N., &#38; Partch, C. L. (2017).
    Animal cryptochromes: Divergent roles in light perception, circadian timekeeping
    and beyond. <i>Photochemistry and Photobiology</i>. Wiley. <a href="https://doi.org/10.1111/php.12677">https://doi.org/10.1111/php.12677</a>'
  chicago: 'Michael, Alicia K., Jennifer L. Fribourgh, Russell N. Van Gelder, and
    Carrie L. Partch. “Animal Cryptochromes: Divergent Roles in Light Perception,
    Circadian Timekeeping and Beyond.” <i>Photochemistry and Photobiology</i>. Wiley,
    2017. <a href="https://doi.org/10.1111/php.12677">https://doi.org/10.1111/php.12677</a>.'
  ieee: 'A. K. Michael, J. L. Fribourgh, R. N. Van Gelder, and C. L. Partch, “Animal
    cryptochromes: Divergent roles in light perception, circadian timekeeping and
    beyond,” <i>Photochemistry and Photobiology</i>, vol. 93, no. 1. Wiley, pp. 128–140,
    2017.'
  ista: 'Michael AK, Fribourgh JL, Van Gelder RN, Partch CL. 2017. Animal cryptochromes:
    Divergent roles in light perception, circadian timekeeping and beyond. Photochemistry
    and Photobiology. 93(1), 128–140.'
  mla: 'Michael, Alicia K., et al. “Animal Cryptochromes: Divergent Roles in Light
    Perception, Circadian Timekeeping and Beyond.” <i>Photochemistry and Photobiology</i>,
    vol. 93, no. 1, Wiley, 2017, pp. 128–40, doi:<a href="https://doi.org/10.1111/php.12677">10.1111/php.12677</a>.'
  short: A.K. Michael, J.L. Fribourgh, R.N. Van Gelder, C.L. Partch, Photochemistry
    and Photobiology 93 (2017) 128–140.
date_created: 2024-03-21T07:57:18Z
date_published: 2017-02-01T00:00:00Z
date_updated: 2024-03-25T12:09:21Z
day: '01'
doi: 10.1111/php.12677
extern: '1'
intvolume: '        93'
issue: '1'
keyword:
- Physical and Theoretical Chemistry
- General Medicine
- Biochemistry
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1111/php.12677
month: '02'
oa: 1
oa_version: Published Version
page: 128-140
publication: Photochemistry and Photobiology
publication_identifier:
  eissn:
  - 1751-1097
  issn:
  - 0031-8655
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Animal cryptochromes: Divergent roles in light perception, circadian timekeeping
  and beyond'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 93
year: '2017'
...
---
_id: '15239'
abstract:
- lang: eng
  text: Using images from the Hubble Space Telescope Advanced Camera for Surveys,
    we measure the rate of cooling of white dwarfs in the globular cluster 47 Tucanae
    and compare it to modelled cooling curves. We examine the effects of the outer
    convective envelope reaching the nearly isothermal degenerate core and the release
    of latent heat during core crystallization on the white dwarf cooling rates. For
    white dwarfs typical of 47 Tuc, the onset of these effects occur at similar times.
    The latent heat released during crystallization is a small heat source. In contrast,
    the heat reservoir of the degenerate core is substantially larger. When the convective
    envelope reaches the nearly isothermal interior of the white dwarf, the star becomes
    brighter than it would be in the absence of this effect. Our modelled cooling
    curves that include this convective coupling closely match the observed luminosity
    function of the white dwarfs in 47 Tuc.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Alysa
  full_name: Obertas, Alysa
  last_name: Obertas
- first_name: Ilaria
  full_name: Caiazzo, Ilaria
  id: 8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d
  last_name: Caiazzo
  orcid: 0000-0002-4770-5388
- first_name: Jeremy
  full_name: Heyl, Jeremy
  last_name: Heyl
- first_name: Harvey
  full_name: Richer, Harvey
  last_name: Richer
- first_name: Jason
  full_name: Kalirai, Jason
  last_name: Kalirai
- first_name: Pier-Emmanuel
  full_name: Tremblay, Pier-Emmanuel
  last_name: Tremblay
citation:
  ama: Obertas A, Caiazzo I, Heyl J, Richer H, Kalirai J, Tremblay P-E. The onset
    of convective coupling and freezing in the white dwarfs of 47 Tucanae. <i>Monthly
    Notices of the Royal Astronomical Society</i>. 2017;474(1):677-682. doi:<a href="https://doi.org/10.1093/mnras/stx2759">10.1093/mnras/stx2759</a>
  apa: Obertas, A., Caiazzo, I., Heyl, J., Richer, H., Kalirai, J., &#38; Tremblay,
    P.-E. (2017). The onset of convective coupling and freezing in the white dwarfs
    of 47 Tucanae. <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford
    University Press. <a href="https://doi.org/10.1093/mnras/stx2759">https://doi.org/10.1093/mnras/stx2759</a>
  chicago: Obertas, Alysa, Ilaria Caiazzo, Jeremy Heyl, Harvey Richer, Jason Kalirai,
    and Pier-Emmanuel Tremblay. “The Onset of Convective Coupling and Freezing in
    the White Dwarfs of 47 Tucanae.” <i>Monthly Notices of the Royal Astronomical
    Society</i>. Oxford University Press, 2017. <a href="https://doi.org/10.1093/mnras/stx2759">https://doi.org/10.1093/mnras/stx2759</a>.
  ieee: A. Obertas, I. Caiazzo, J. Heyl, H. Richer, J. Kalirai, and P.-E. Tremblay,
    “The onset of convective coupling and freezing in the white dwarfs of 47 Tucanae,”
    <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 474, no. 1. Oxford
    University Press, pp. 677–682, 2017.
  ista: Obertas A, Caiazzo I, Heyl J, Richer H, Kalirai J, Tremblay P-E. 2017. The
    onset of convective coupling and freezing in the white dwarfs of 47 Tucanae. Monthly
    Notices of the Royal Astronomical Society. 474(1), 677–682.
  mla: Obertas, Alysa, et al. “The Onset of Convective Coupling and Freezing in the
    White Dwarfs of 47 Tucanae.” <i>Monthly Notices of the Royal Astronomical Society</i>,
    vol. 474, no. 1, Oxford University Press, 2017, pp. 677–82, doi:<a href="https://doi.org/10.1093/mnras/stx2759">10.1093/mnras/stx2759</a>.
  short: A. Obertas, I. Caiazzo, J. Heyl, H. Richer, J. Kalirai, P.-E. Tremblay, Monthly
    Notices of the Royal Astronomical Society 474 (2017) 677–682.
date_created: 2024-03-26T10:40:05Z
date_published: 2017-10-24T00:00:00Z
date_updated: 2024-04-08T07:04:10Z
day: '24'
doi: 10.1093/mnras/stx2759
extern: '1'
external_id:
  arxiv:
  - '1709.08097'
intvolume: '       474'
issue: '1'
keyword:
- Space and Planetary Science
- Astronomy and Astrophysics
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.1709.08097
month: '10'
oa: 1
oa_version: Preprint
page: 677-682
publication: Monthly Notices of the Royal Astronomical Society
publication_identifier:
  eissn:
  - 1365-2966
  issn:
  - 0035-8711
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: The onset of convective coupling and freezing in the white dwarfs of 47 Tucanae
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 474
year: '2017'
...
---
_id: '15240'
abstract:
- lang: eng
  text: "Multi-epoch observations with the Advanced Camera Survey and WFC3 on the
    Hubble Space Telescope provide a unique and comprehensive probe of stellar dynamics
    within 47 Tucanae. We confront analytic models of the globular cluster with the
    observed stellar proper motions that probe along the main sequence from just above
    0.8–0.1M⊙ as well as white dwarfs younger than 1 Gyr. One field lies just beyond
    the half-light radius where dynamical models (e.g., lowered Maxwellian distributions)
    make robust predictions for the stellar proper motions. The observed proper motions
    in this outer field show evidence for anisotropy in the velocity distribution
    as well as skewness; the latter is evidence of rotation. The measured velocity
    dispersions and surface brightness distributions agree in detail with a rotating
    anisotropic model of the stellar distribution function with mild dependence of
    the proper-motion dispersion on mass. However, the best-fitting models underpredict
    the rotation and skewness of the stellar velocities. In the second field, centered
    on the core of the cluster, the mass segregation in proper motion is much stronger.
    Nevertheless the model developed in the outer field can be extended inward by
    taking this mass segregation into account in a heuristic fashion. The proper motions
    of the main-sequence stars yield a mass estimate of the cluster of \r\n at a distance
    of 4.7 kpc. By comparing the proper motions of a sample of giant and subgiant
    stars with the observed radial velocities we estimate the distance to the cluster
    kinematically to be 4.29 ± 0.47 kpc."
article_number: '186'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: J.
  full_name: Heyl, J.
  last_name: Heyl
- first_name: Ilaria
  full_name: Caiazzo, Ilaria
  id: 8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d
  last_name: Caiazzo
  orcid: 0000-0002-4770-5388
- first_name: H.
  full_name: Richer, H.
  last_name: Richer
- first_name: J.
  full_name: Anderson, J.
  last_name: Anderson
- first_name: J.
  full_name: Kalirai, J.
  last_name: Kalirai
- first_name: J.
  full_name: Parada, J.
  last_name: Parada
citation:
  ama: 'Heyl J, Caiazzo I, Richer H, Anderson J, Kalirai J, Parada J. Deep HST imaging
    in 47 Tucanae: A global dynamical model. <i>The Astrophysical Journal</i>. 2017;850(2).
    doi:<a href="https://doi.org/10.3847/1538-4357/aa974f">10.3847/1538-4357/aa974f</a>'
  apa: 'Heyl, J., Caiazzo, I., Richer, H., Anderson, J., Kalirai, J., &#38; Parada,
    J. (2017). Deep HST imaging in 47 Tucanae: A global dynamical model. <i>The Astrophysical
    Journal</i>. American Astronomical Society. <a href="https://doi.org/10.3847/1538-4357/aa974f">https://doi.org/10.3847/1538-4357/aa974f</a>'
  chicago: 'Heyl, J., Ilaria Caiazzo, H. Richer, J. Anderson, J. Kalirai, and J. Parada.
    “Deep HST Imaging in 47 Tucanae: A Global Dynamical Model.” <i>The Astrophysical
    Journal</i>. American Astronomical Society, 2017. <a href="https://doi.org/10.3847/1538-4357/aa974f">https://doi.org/10.3847/1538-4357/aa974f</a>.'
  ieee: 'J. Heyl, I. Caiazzo, H. Richer, J. Anderson, J. Kalirai, and J. Parada, “Deep
    HST imaging in 47 Tucanae: A global dynamical model,” <i>The Astrophysical Journal</i>,
    vol. 850, no. 2. American Astronomical Society, 2017.'
  ista: 'Heyl J, Caiazzo I, Richer H, Anderson J, Kalirai J, Parada J. 2017. Deep
    HST imaging in 47 Tucanae: A global dynamical model. The Astrophysical Journal.
    850(2), 186.'
  mla: 'Heyl, J., et al. “Deep HST Imaging in 47 Tucanae: A Global Dynamical Model.”
    <i>The Astrophysical Journal</i>, vol. 850, no. 2, 186, American Astronomical
    Society, 2017, doi:<a href="https://doi.org/10.3847/1538-4357/aa974f">10.3847/1538-4357/aa974f</a>.'
  short: J. Heyl, I. Caiazzo, H. Richer, J. Anderson, J. Kalirai, J. Parada, The Astrophysical
    Journal 850 (2017).
date_created: 2024-03-26T10:40:23Z
date_published: 2017-12-01T00:00:00Z
date_updated: 2024-04-08T07:04:35Z
day: '01'
doi: 10.3847/1538-4357/aa974f
extern: '1'
external_id:
  arxiv:
  - '1710.10666'
intvolume: '       850'
issue: '2'
keyword:
- Space and Planetary Science
- Astronomy and Astrophysics
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.1710.10666
month: '12'
oa: 1
oa_version: Preprint
publication: The Astrophysical Journal
publication_identifier:
  eissn:
  - 1538-4357
  issn:
  - 0004-637X
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Deep HST imaging in 47 Tucanae: A global dynamical model'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 850
year: '2017'
...
---
_id: '15241'
abstract:
- lang: eng
  text: We present a model to account for the observed debris discs around young white
    dwarfs and the presence of metal lines in their spectra. Stellar evolution models
    predict that the mass-loss on the AGB will be pulsed; furthermore, observations
    indicate that the bulk of the mass-loss occurs on the AGB. In this case, if the
    progenitors of the white dwarfs had remnants of planetary formation like the Sun’s
    Oort cloud or the Kuiper Belt and a planet lying within that cloud or nearby,
    we find that up to 2 per cent of the planetesimals will fall either into planet-crossing
    orbits or into chaotic regions after the mass-loss, depending on the location
    and mass of the planet (from Mars to Neptune). This yields a sufficient mass of
    comets that can be scattered towards the star, form a debris disc and pollute
    the atmosphere.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Ilaria
  full_name: Caiazzo, Ilaria
  id: 8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d
  last_name: Caiazzo
  orcid: 0000-0002-4770-5388
- first_name: Jeremy S.
  full_name: Heyl, Jeremy S.
  last_name: Heyl
citation:
  ama: Caiazzo I, Heyl JS. Polluting white dwarfs with perturbed exo-comets. <i>Monthly
    Notices of the Royal Astronomical Society</i>. 2017;469(3):2750-2759. doi:<a href="https://doi.org/10.1093/mnras/stx1036">10.1093/mnras/stx1036</a>
  apa: Caiazzo, I., &#38; Heyl, J. S. (2017). Polluting white dwarfs with perturbed
    exo-comets. <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University
    Press. <a href="https://doi.org/10.1093/mnras/stx1036">https://doi.org/10.1093/mnras/stx1036</a>
  chicago: Caiazzo, Ilaria, and Jeremy S. Heyl. “Polluting White Dwarfs with Perturbed
    Exo-Comets.” <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford
    University Press, 2017. <a href="https://doi.org/10.1093/mnras/stx1036">https://doi.org/10.1093/mnras/stx1036</a>.
  ieee: I. Caiazzo and J. S. Heyl, “Polluting white dwarfs with perturbed exo-comets,”
    <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 469, no. 3. Oxford
    University Press, pp. 2750–2759, 2017.
  ista: Caiazzo I, Heyl JS. 2017. Polluting white dwarfs with perturbed exo-comets.
    Monthly Notices of the Royal Astronomical Society. 469(3), 2750–2759.
  mla: Caiazzo, Ilaria, and Jeremy S. Heyl. “Polluting White Dwarfs with Perturbed
    Exo-Comets.” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 469,
    no. 3, Oxford University Press, 2017, pp. 2750–59, doi:<a href="https://doi.org/10.1093/mnras/stx1036">10.1093/mnras/stx1036</a>.
  short: I. Caiazzo, J.S. Heyl, Monthly Notices of the Royal Astronomical Society
    469 (2017) 2750–2759.
date_created: 2024-03-26T10:40:45Z
date_published: 2017-05-01T00:00:00Z
date_updated: 2024-10-14T12:33:43Z
day: '01'
doi: 10.1093/mnras/stx1036
extern: '1'
external_id:
  arxiv:
  - '1702.07682'
intvolume: '       469'
issue: '3'
keyword:
- Space and Planetary Science
- Astronomy and Astrophysics
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.1702.07682
month: '05'
oa: 1
oa_version: Preprint
page: 2750-2759
publication: Monthly Notices of the Royal Astronomical Society
publication_identifier:
  eissn:
  - 1365-2966
  issn:
  - 0035-8711
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Polluting white dwarfs with perturbed exo-comets
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 469
year: '2017'
...
---
_id: '15243'
abstract:
- lang: eng
  text: High-energy (>250 keV) emission has been detected persisting for several tens
    of seconds after the initial spike of magnetar giant flares (GFs). It has been
    conjectured that this emission might arise via inverse Compton scattering in a
    highly extended corona generated by super-Eddington outflows high up in the magnetosphere.
    In this paper, we undertake a detailed examination of this model. We investigate
    the properties of the required scatterers, and whether the mechanism is consistent
    with the degree of pulsed emission observed in the tail of the GF. We conclude
    that the mechanism is consistent with current data, although the origin of the
    scattering population remains an open question. We propose an alternative picture
    in which the emission is closer to that star and is dominated by synchrotron radiation.
    The Reuven Ramaty High Energy Solar Spectroscopic Imager observations of the 2004
    December flare modestly favour this latter picture. We assess the prospects for
    the Fermi Gamma-ray Space Telescope to detect and characterize a similar high-energy
    component in a future GF. Such a detection should help to resolve some of the
    outstanding issues.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: C.
  full_name: Elenbaas, C.
  last_name: Elenbaas
- first_name: D.
  full_name: Huppenkothen, D.
  last_name: Huppenkothen
- first_name: C.
  full_name: Omand, C.
  last_name: Omand
- first_name: A. L.
  full_name: Watts, A. L.
  last_name: Watts
- first_name: E.
  full_name: Bissaldi, E.
  last_name: Bissaldi
- first_name: Ilaria
  full_name: Caiazzo, Ilaria
  id: 8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d
  last_name: Caiazzo
  orcid: 0000-0002-4770-5388
- first_name: J.
  full_name: Heyl, J.
  last_name: Heyl
citation:
  ama: Elenbaas C, Huppenkothen D, Omand C, et al. Magnetar giant flare high-energy
    emission. <i>Monthly Notices of the Royal Astronomical Society</i>. 2017;471(2):1856-1872.
    doi:<a href="https://doi.org/10.1093/mnras/stx1727">10.1093/mnras/stx1727</a>
  apa: Elenbaas, C., Huppenkothen, D., Omand, C., Watts, A. L., Bissaldi, E., Caiazzo,
    I., &#38; Heyl, J. (2017). Magnetar giant flare high-energy emission. <i>Monthly
    Notices of the Royal Astronomical Society</i>. Oxford University Press. <a href="https://doi.org/10.1093/mnras/stx1727">https://doi.org/10.1093/mnras/stx1727</a>
  chicago: Elenbaas, C., D. Huppenkothen, C. Omand, A. L. Watts, E. Bissaldi, Ilaria
    Caiazzo, and J. Heyl. “Magnetar Giant Flare High-Energy Emission.” <i>Monthly
    Notices of the Royal Astronomical Society</i>. Oxford University Press, 2017.
    <a href="https://doi.org/10.1093/mnras/stx1727">https://doi.org/10.1093/mnras/stx1727</a>.
  ieee: C. Elenbaas <i>et al.</i>, “Magnetar giant flare high-energy emission,” <i>Monthly
    Notices of the Royal Astronomical Society</i>, vol. 471, no. 2. Oxford University
    Press, pp. 1856–1872, 2017.
  ista: Elenbaas C, Huppenkothen D, Omand C, Watts AL, Bissaldi E, Caiazzo I, Heyl
    J. 2017. Magnetar giant flare high-energy emission. Monthly Notices of the Royal
    Astronomical Society. 471(2), 1856–1872.
  mla: Elenbaas, C., et al. “Magnetar Giant Flare High-Energy Emission.” <i>Monthly
    Notices of the Royal Astronomical Society</i>, vol. 471, no. 2, Oxford University
    Press, 2017, pp. 1856–72, doi:<a href="https://doi.org/10.1093/mnras/stx1727">10.1093/mnras/stx1727</a>.
  short: C. Elenbaas, D. Huppenkothen, C. Omand, A.L. Watts, E. Bissaldi, I. Caiazzo,
    J. Heyl, Monthly Notices of the Royal Astronomical Society 471 (2017) 1856–1872.
date_created: 2024-03-26T10:41:24Z
date_published: 2017-07-13T00:00:00Z
date_updated: 2024-04-08T07:05:47Z
day: '13'
doi: 10.1093/mnras/stx1727
extern: '1'
external_id:
  arxiv:
  - '1707.02922'
intvolume: '       471'
issue: '2'
keyword:
- Space and Planetary Science
- Astronomy and Astrophysics
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.1707.02922
month: '07'
oa: 1
oa_version: Preprint
page: 1856-1872
publication: Monthly Notices of the Royal Astronomical Society
publication_identifier:
  eissn:
  - 1365-2966
  issn:
  - 0035-8711
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Magnetar giant flare high-energy emission
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 471
year: '2017'
...
---
_id: '1528'
abstract:
- lang: eng
  text: 'We consider N×N Hermitian random matrices H consisting of blocks of size
    M≥N6/7. The matrix elements are i.i.d. within the blocks, close to a Gaussian
    in the four moment matching sense, but their distribution varies from block to
    block to form a block-band structure, with an essential band width M. We show
    that the entries of the Green’s function G(z)=(H−z)−1 satisfy the local semicircle
    law with spectral parameter z=E+iη down to the real axis for any η≫N−1, using
    a combination of the supersymmetry method inspired by Shcherbina (J Stat Phys
    155(3): 466–499, 2014) and the Green’s function comparison strategy. Previous
    estimates were valid only for η≫M−1. The new estimate also implies that the eigenvectors
    in the middle of the spectrum are fully delocalized.'
acknowledgement: "Z. Bao was supported by ERC Advanced Grant RANMAT No. 338804; L.
  Erdős was partially supported by ERC Advanced Grant RANMAT No. 338804.\r\nOpen access
  funding provided by Institute of Science and Technology (IST Austria). The authors
  are very grateful to the anonymous referees for careful reading and valuable comments,
  which helped to improve the organization."
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Zhigang
  full_name: Bao, Zhigang
  id: 442E6A6C-F248-11E8-B48F-1D18A9856A87
  last_name: Bao
  orcid: 0000-0003-3036-1475
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
citation:
  ama: Bao Z, Erdös L. Delocalization for a class of random block band matrices. <i>Probability
    Theory and Related Fields</i>. 2017;167(3-4):673-776. doi:<a href="https://doi.org/10.1007/s00440-015-0692-y">10.1007/s00440-015-0692-y</a>
  apa: Bao, Z., &#38; Erdös, L. (2017). Delocalization for a class of random block
    band matrices. <i>Probability Theory and Related Fields</i>. Springer. <a href="https://doi.org/10.1007/s00440-015-0692-y">https://doi.org/10.1007/s00440-015-0692-y</a>
  chicago: Bao, Zhigang, and László Erdös. “Delocalization for a Class of Random Block
    Band Matrices.” <i>Probability Theory and Related Fields</i>. Springer, 2017.
    <a href="https://doi.org/10.1007/s00440-015-0692-y">https://doi.org/10.1007/s00440-015-0692-y</a>.
  ieee: Z. Bao and L. Erdös, “Delocalization for a class of random block band matrices,”
    <i>Probability Theory and Related Fields</i>, vol. 167, no. 3–4. Springer, pp.
    673–776, 2017.
  ista: Bao Z, Erdös L. 2017. Delocalization for a class of random block band matrices.
    Probability Theory and Related Fields. 167(3–4), 673–776.
  mla: Bao, Zhigang, and László Erdös. “Delocalization for a Class of Random Block
    Band Matrices.” <i>Probability Theory and Related Fields</i>, vol. 167, no. 3–4,
    Springer, 2017, pp. 673–776, doi:<a href="https://doi.org/10.1007/s00440-015-0692-y">10.1007/s00440-015-0692-y</a>.
  short: Z. Bao, L. Erdös, Probability Theory and Related Fields 167 (2017) 673–776.
corr_author: '1'
date_created: 2018-12-11T11:52:32Z
date_published: 2017-04-01T00:00:00Z
date_updated: 2026-04-16T09:55:56Z
day: '01'
ddc:
- '530'
department:
- _id: LaEr
doi: 10.1007/s00440-015-0692-y
ec_funded: 1
external_id:
  isi:
  - '000398842700004'
file:
- access_level: open_access
  checksum: 67afa85ff1e220cbc1f9f477a828513c
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:08:05Z
  date_updated: 2020-07-14T12:45:00Z
  file_id: '4665'
  file_name: IST-2016-489-v1+1_s00440-015-0692-y.pdf
  file_size: 1615755
  relation: main_file
file_date_updated: 2020-07-14T12:45:00Z
has_accepted_license: '1'
intvolume: '       167'
isi: 1
issue: 3-4
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 673 - 776
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '338804'
  name: Random matrices, universality and disordered quantum systems
publication: Probability Theory and Related Fields
publication_identifier:
  issn:
  - 0178-8051
publication_status: published
publisher: Springer
publist_id: '5644'
pubrep_id: '489'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Delocalization for a class of random block band matrices
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 167
year: '2017'
...
---
_id: '169'
abstract:
- lang: eng
  text: We show that a twisted variant of Linnik’s conjecture on sums of Kloosterman
    sums leads to an optimal covering exponent for S3.
article_processing_charge: No
arxiv: 1
author:
- first_name: Timothy D
  full_name: Browning, Timothy D
  id: 35827D50-F248-11E8-B48F-1D18A9856A87
  last_name: Browning
  orcid: 0000-0002-8314-0177
- first_name: Vinay
  full_name: Kumaraswamy, Vinay
  last_name: Kumaraswamy
- first_name: Rapael
  full_name: Steiner, Rapael
  last_name: Steiner
citation:
  ama: Browning TD, Kumaraswamy V, Steiner R. Twisted Linnik implies optimal covering
    exponent for S3. <i>International Mathematics Research Notices</i>. 2017. doi:<a
    href="https://doi.org/10.1093/imrn/rnx116">10.1093/imrn/rnx116</a>
  apa: Browning, T. D., Kumaraswamy, V., &#38; Steiner, R. (2017). Twisted Linnik
    implies optimal covering exponent for S3. <i>International Mathematics Research
    Notices</i>. Oxford University Press. <a href="https://doi.org/10.1093/imrn/rnx116">https://doi.org/10.1093/imrn/rnx116</a>
  chicago: Browning, Timothy D, Vinay Kumaraswamy, and Rapael Steiner. “Twisted Linnik
    Implies Optimal Covering Exponent for S3.” <i>International Mathematics Research
    Notices</i>. Oxford University Press, 2017. <a href="https://doi.org/10.1093/imrn/rnx116">https://doi.org/10.1093/imrn/rnx116</a>.
  ieee: T. D. Browning, V. Kumaraswamy, and R. Steiner, “Twisted Linnik implies optimal
    covering exponent for S3,” <i>International Mathematics Research Notices</i>.
    Oxford University Press, 2017.
  ista: Browning TD, Kumaraswamy V, Steiner R. 2017. Twisted Linnik implies optimal
    covering exponent for S3. International Mathematics Research Notices.
  mla: Browning, Timothy D., et al. “Twisted Linnik Implies Optimal Covering Exponent
    for S3.” <i>International Mathematics Research Notices</i>, Oxford University
    Press, 2017, doi:<a href="https://doi.org/10.1093/imrn/rnx116">10.1093/imrn/rnx116</a>.
  short: T.D. Browning, V. Kumaraswamy, R. Steiner, International Mathematics Research
    Notices (2017).
date_created: 2018-12-11T11:44:59Z
date_published: 2017-06-19T00:00:00Z
date_updated: 2021-01-12T06:52:32Z
day: '19'
doi: 10.1093/imrn/rnx116
extern: '1'
external_id:
  arxiv:
  - '1609.06097'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1609.06097
month: '06'
oa: 1
oa_version: None
publication: International Mathematics Research Notices
publication_status: published
publisher: Oxford University Press
publist_id: '7752'
quality_controlled: '1'
status: public
title: Twisted Linnik implies optimal covering exponent for S3
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2017'
...
---
_id: '172'
abstract:
- lang: eng
  text: We study strong approximation for some algebraic varieties over ℚ which are
    defined using norm forms. This allows us to confirm a special case of a conjecture
    due to Harpaz and Wittenberg.
article_processing_charge: No
arxiv: 1
author:
- first_name: Timothy D
  full_name: Browning, Timothy D
  id: 35827D50-F248-11E8-B48F-1D18A9856A87
  last_name: Browning
  orcid: 0000-0002-8314-0177
- first_name: Damaris
  full_name: Schindler, Damaris
  last_name: Schindler
citation:
  ama: Browning TD, Schindler D. Strong approximation and a conjecture of Harpaz and
    Wittenberg. <i>International Mathematics Research Notices</i>. 2017. doi:<a href="https://doi.org/10.1093/imrn/rnx252">10.1093/imrn/rnx252</a>
  apa: Browning, T. D., &#38; Schindler, D. (2017). Strong approximation and a conjecture
    of Harpaz and Wittenberg. <i>International Mathematics Research Notices</i>. Oxford
    University Press. <a href="https://doi.org/10.1093/imrn/rnx252">https://doi.org/10.1093/imrn/rnx252</a>
  chicago: Browning, Timothy D, and Damaris Schindler. “Strong Approximation and a
    Conjecture of Harpaz and Wittenberg.” <i>International Mathematics Research Notices</i>.
    Oxford University Press, 2017. <a href="https://doi.org/10.1093/imrn/rnx252">https://doi.org/10.1093/imrn/rnx252</a>.
  ieee: T. D. Browning and D. Schindler, “Strong approximation and a conjecture of
    Harpaz and Wittenberg,” <i>International Mathematics Research Notices</i>. Oxford
    University Press, 2017.
  ista: Browning TD, Schindler D. 2017. Strong approximation and a conjecture of Harpaz
    and Wittenberg. International Mathematics Research Notices.
  mla: Browning, Timothy D., and Damaris Schindler. “Strong Approximation and a Conjecture
    of Harpaz and Wittenberg.” <i>International Mathematics Research Notices</i>,
    Oxford University Press, 2017, doi:<a href="https://doi.org/10.1093/imrn/rnx252">10.1093/imrn/rnx252</a>.
  short: T.D. Browning, D. Schindler, International Mathematics Research Notices (2017).
date_created: 2018-12-11T11:45:00Z
date_published: 2017-10-30T00:00:00Z
date_updated: 2021-01-12T06:52:45Z
day: '30'
doi: 10.1093/imrn/rnx252
extern: '1'
external_id:
  arxiv:
  - '1509.07744'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1509.07744
month: '10'
oa: 1
oa_version: None
publication: International Mathematics Research Notices
publication_status: published
publisher: Oxford University Press
publist_id: '7749'
quality_controlled: '1'
status: public
title: Strong approximation and a conjecture of Harpaz and Wittenberg
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2017'
...
---
OA_place: repository
OA_type: green
_id: '19474'
abstract:
- lang: eng
  text: The complex behaviors underlying reward seeking and consumption are integral
    to organism survival. The hypothalamus and mesolimbic dopamine system are key
    mediators of these behaviors, yet regulation of appetitive and consummatory behaviors
    outside of these regions is poorly understood. The central nucleus of the amygdala
    (CeA) has been implicated in feeding and reward, but the neurons and circuit mechanisms
    that positively regulate these behaviors remain unclear. Here, we defined the
    neuronal mechanisms by which CeA neurons promote food consumption. Using in vivo
    activity manipulations and Ca2+ imaging in mice, we found that GABAergic serotonin
    receptor 2a (Htr2a)-expressing CeA neurons modulate food consumption, promote
    positive reinforcement and are active in vivo during eating. We demonstrated electrophysiologically,
    anatomically and behaviorally that intra-CeA and long-range circuit mechanisms
    underlie these behaviors. Finally, we showed that CeAHtr2a neurons receive inputs
    from feeding-relevant brain regions. Our results illustrate how defined CeA neural
    circuits positively regulate food consumption.
article_processing_charge: No
article_type: original
author:
- first_name: Amelia May Barnett
  full_name: Douglass, Amelia May Barnett
  id: de5f6fda-80fb-11ef-996f-a8c4ecd8e289
  last_name: Douglass
  orcid: 0000-0001-5398-6473
- first_name: Hakan
  full_name: Kucukdereli, Hakan
  last_name: Kucukdereli
- first_name: Marion
  full_name: Ponserre, Marion
  last_name: Ponserre
- first_name: Milica
  full_name: Markovic, Milica
  last_name: Markovic
- first_name: Jan
  full_name: Gründemann, Jan
  last_name: Gründemann
- first_name: Cornelia
  full_name: Strobel, Cornelia
  last_name: Strobel
- first_name: Pilar L
  full_name: Alcala Morales, Pilar L
  last_name: Alcala Morales
- first_name: Karl-Klaus
  full_name: Conzelmann, Karl-Klaus
  last_name: Conzelmann
- first_name: Andreas
  full_name: Lüthi, Andreas
  last_name: Lüthi
- first_name: Rüdiger
  full_name: Klein, Rüdiger
  last_name: Klein
citation:
  ama: Douglass AM, Kucukdereli H, Ponserre M, et al. Central amygdala circuits modulate
    food consumption through a positive-valence mechanism. <i>Nature Neuroscience</i>.
    2017;20(10):1384-1394. doi:<a href="https://doi.org/10.1038/nn.4623">10.1038/nn.4623</a>
  apa: Douglass, A. M., Kucukdereli, H., Ponserre, M., Markovic, M., Gründemann, J.,
    Strobel, C., … Klein, R. (2017). Central amygdala circuits modulate food consumption
    through a positive-valence mechanism. <i>Nature Neuroscience</i>. Springer Nature.
    <a href="https://doi.org/10.1038/nn.4623">https://doi.org/10.1038/nn.4623</a>
  chicago: Douglass, Amelia M., Hakan Kucukdereli, Marion Ponserre, Milica Markovic,
    Jan Gründemann, Cornelia Strobel, Pilar L Alcala Morales, Karl-Klaus Conzelmann,
    Andreas Lüthi, and Rüdiger Klein. “Central Amygdala Circuits Modulate Food Consumption
    through a Positive-Valence Mechanism.” <i>Nature Neuroscience</i>. Springer Nature,
    2017. <a href="https://doi.org/10.1038/nn.4623">https://doi.org/10.1038/nn.4623</a>.
  ieee: A. M. Douglass <i>et al.</i>, “Central amygdala circuits modulate food consumption
    through a positive-valence mechanism,” <i>Nature Neuroscience</i>, vol. 20, no.
    10. Springer Nature, pp. 1384–1394, 2017.
  ista: Douglass AM, Kucukdereli H, Ponserre M, Markovic M, Gründemann J, Strobel
    C, Alcala Morales PL, Conzelmann K-K, Lüthi A, Klein R. 2017. Central amygdala
    circuits modulate food consumption through a positive-valence mechanism. Nature
    Neuroscience. 20(10), 1384–1394.
  mla: Douglass, Amelia M., et al. “Central Amygdala Circuits Modulate Food Consumption
    through a Positive-Valence Mechanism.” <i>Nature Neuroscience</i>, vol. 20, no.
    10, Springer Nature, 2017, pp. 1384–94, doi:<a href="https://doi.org/10.1038/nn.4623">10.1038/nn.4623</a>.
  short: A.M. Douglass, H. Kucukdereli, M. Ponserre, M. Markovic, J. Gründemann, C.
    Strobel, P.L. Alcala Morales, K.-K. Conzelmann, A. Lüthi, R. Klein, Nature Neuroscience
    20 (2017) 1384–1394.
date_created: 2025-04-03T12:30:57Z
date_published: 2017-10-01T00:00:00Z
date_updated: 2025-07-10T11:51:42Z
day: '01'
doi: 10.1038/nn.4623
extern: '1'
external_id:
  pmid:
  - '28825719 '
intvolume: '        20'
issue: '10'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/145375
month: '10'
oa: 1
oa_version: Preprint
page: 1384-1394
pmid: 1
publication: Nature Neuroscience
publication_identifier:
  eissn:
  - 1546-1726
  issn:
  - 1097-6256
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Central amygdala circuits modulate food consumption through a positive-valence
  mechanism
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 20
year: '2017'
...
---
_id: '443'
abstract:
- lang: eng
  text: Pancreatic cancer has a five-year survival rate of ~8%, with characteristic
    molecular heterogeneity and restricted treatment options. Targeting metabolism
    has emerged as a potentially effective therapeutic strategy for cancers such as
    pancreatic cancer, which are driven by genetic alterations that are not tractable
    drug targets. Although somatic mitochondrial genome (mtDNA) mutations have been
    observed in various tumors types, understanding of metabolic genotype-phenotype
    relationships is limited.
article_processing_charge: No
author:
- first_name: Rae
  full_name: Hardie, Rae
  last_name: Hardie
- first_name: Ellen
  full_name: Van Dam, Ellen
  last_name: Van Dam
- first_name: Mark
  full_name: Cowley, Mark
  last_name: Cowley
- first_name: Ting
  full_name: Han, Ting
  last_name: Han
- first_name: Seher
  full_name: Balaban, Seher
  last_name: Balaban
- first_name: Marina
  full_name: Pajic, Marina
  last_name: Pajic
- first_name: Mark
  full_name: Pinese, Mark
  last_name: Pinese
- first_name: Mary
  full_name: Iconomou, Mary
  last_name: Iconomou
- first_name: Robert
  full_name: Shearer, Robert
  last_name: Shearer
- first_name: Jessie
  full_name: Mckenna, Jessie
  last_name: Mckenna
- first_name: David
  full_name: Miller, David
  last_name: Miller
- first_name: Nicola
  full_name: Waddell, Nicola
  last_name: Waddell
- first_name: John
  full_name: Pearson, John
  last_name: Pearson
- first_name: Sean
  full_name: Grimmond, Sean
  last_name: Grimmond
- first_name: Leonid A
  full_name: Sazanov, Leonid A
  id: 338D39FE-F248-11E8-B48F-1D18A9856A87
  last_name: Sazanov
  orcid: 0000-0002-0977-7989
- first_name: Andrew
  full_name: Biankin, Andrew
  last_name: Biankin
- first_name: Silas
  full_name: Villas Boas, Silas
  last_name: Villas Boas
- first_name: Andrew
  full_name: Hoy, Andrew
  last_name: Hoy
- first_name: Nigel
  full_name: Turner, Nigel
  last_name: Turner
- first_name: Darren
  full_name: Saunders, Darren
  last_name: Saunders
citation:
  ama: Hardie R, Van Dam E, Cowley M, et al. Mitochondrial mutations and metabolic
    adaptation in pancreatic cancer. <i>Cancer &#38; Metabolism</i>. 2017;5(2). doi:<a
    href="https://doi.org/10.1186/s40170-017-0164-1">10.1186/s40170-017-0164-1</a>
  apa: Hardie, R., Van Dam, E., Cowley, M., Han, T., Balaban, S., Pajic, M., … Saunders,
    D. (2017). Mitochondrial mutations and metabolic adaptation in pancreatic cancer.
    <i>Cancer &#38; Metabolism</i>. BioMed Central. <a href="https://doi.org/10.1186/s40170-017-0164-1">https://doi.org/10.1186/s40170-017-0164-1</a>
  chicago: Hardie, Rae, Ellen Van Dam, Mark Cowley, Ting Han, Seher Balaban, Marina
    Pajic, Mark Pinese, et al. “Mitochondrial Mutations and Metabolic Adaptation in
    Pancreatic Cancer.” <i>Cancer &#38; Metabolism</i>. BioMed Central, 2017. <a href="https://doi.org/10.1186/s40170-017-0164-1">https://doi.org/10.1186/s40170-017-0164-1</a>.
  ieee: R. Hardie <i>et al.</i>, “Mitochondrial mutations and metabolic adaptation
    in pancreatic cancer,” <i>Cancer &#38; Metabolism</i>, vol. 5, no. 2. BioMed Central,
    2017.
  ista: Hardie R, Van Dam E, Cowley M, Han T, Balaban S, Pajic M, Pinese M, Iconomou
    M, Shearer R, Mckenna J, Miller D, Waddell N, Pearson J, Grimmond S, Sazanov LA,
    Biankin A, Villas Boas S, Hoy A, Turner N, Saunders D. 2017. Mitochondrial mutations
    and metabolic adaptation in pancreatic cancer. Cancer &#38; Metabolism. 5(2).
  mla: Hardie, Rae, et al. “Mitochondrial Mutations and Metabolic Adaptation in Pancreatic
    Cancer.” <i>Cancer &#38; Metabolism</i>, vol. 5, no. 2, BioMed Central, 2017,
    doi:<a href="https://doi.org/10.1186/s40170-017-0164-1">10.1186/s40170-017-0164-1</a>.
  short: R. Hardie, E. Van Dam, M. Cowley, T. Han, S. Balaban, M. Pajic, M. Pinese,
    M. Iconomou, R. Shearer, J. Mckenna, D. Miller, N. Waddell, J. Pearson, S. Grimmond,
    L.A. Sazanov, A. Biankin, S. Villas Boas, A. Hoy, N. Turner, D. Saunders, Cancer
    &#38; Metabolism 5 (2017).
date_created: 2018-12-11T11:46:30Z
date_published: 2017-01-30T00:00:00Z
date_updated: 2025-09-18T10:03:47Z
day: '30'
ddc:
- '570'
doi: 10.1186/s40170-017-0164-1
extern: '1'
external_id:
  isi:
  - '000396463900001'
file:
- access_level: open_access
  checksum: 337a65786875f64a1fe9fc0ac24767dc
  content_type: application/pdf
  creator: dernst
  date_created: 2019-01-22T08:17:56Z
  date_updated: 2020-07-14T12:46:29Z
  file_id: '5868'
  file_name: 2017_Cancer_Hardie.pdf
  file_size: 1609174
  relation: main_file
file_date_updated: 2020-07-14T12:46:29Z
has_accepted_license: '1'
intvolume: '         5'
isi: 1
issue: '2'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
publication: Cancer & Metabolism
publication_status: published
publisher: BioMed Central
publist_id: '7380'
quality_controlled: '1'
status: public
title: Mitochondrial mutations and metabolic adaptation in pancreatic cancer
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 5
year: '2017'
...
---
_id: '444'
abstract:
- lang: eng
  text: Complex I (NADH:ubiquinone oxidoreductase) plays a central role in cellular
    energy generation, contributing to the proton motive force used to produce ATP.
    It couples the transfer of two electrons between NADH and quinone to translocation
    of four protons across the membrane. It is the largest protein assembly of bacterial
    and mitochondrial respiratory chains, composed, in mammals, of up to 45 subunits
    with a total molecular weight of ∼1 MDa. Bacterial enzyme is about half the size,
    providing the important “minimal” model of complex I. The l-shaped complex consists
    of a hydrophilic arm, where electron transfer occurs, and a membrane arm, where
    proton translocation takes place. Previously, we have solved the crystal structures
    of the hydrophilic domain of complex I from Thermus thermophilus and of the membrane
    domain from Escherichia coli, followed by the atomic structure of intact, entire
    complex I from T. thermophilus. Recently, we have solved by cryo-EM a first complete
    atomic structure of mammalian (ovine) mitochondrial complex I. Core subunits are
    well conserved from the bacterial version, whilst supernumerary subunits form
    an interlinked, stabilizing shell around the core. Subunits containing additional
    cofactors, including Zn ion, NADPH and phosphopantetheine, probably have regulatory
    roles. Dysfunction of mitochondrial complex I is implicated in many human neurodegenerative
    diseases. The structure of mammalian enzyme provides many insights into complex
    I mechanism, assembly, maturation and dysfunction, allowing detailed molecular
    analysis of disease-causing mutations.
author:
- first_name: Leonid A
  full_name: Sazanov, Leonid A
  id: 338D39FE-F248-11E8-B48F-1D18A9856A87
  last_name: Sazanov
  orcid: 0000-0002-0977-7989
citation:
  ama: 'Sazanov LA. Structure of respiratory complex I: “Minimal” bacterial and “de
    luxe” mammalian versions. In: Wikström M, ed. <i>Mechanisms of Primary Energy
    Transduction in Biology </i>. Mechanisms of Primary Energy Transduction in Biology
    . Royal Society of Chemistry; 2017:25-59. doi:<a href="https://doi.org/10.1039/9781788010405-00025">10.1039/9781788010405-00025</a>'
  apa: 'Sazanov, L. A. (2017). Structure of respiratory complex I: “Minimal” bacterial
    and “de luxe” mammalian versions. In M. Wikström (Ed.), <i>Mechanisms of primary
    energy transduction in biology </i> (pp. 25–59). Royal Society of Chemistry. <a
    href="https://doi.org/10.1039/9781788010405-00025">https://doi.org/10.1039/9781788010405-00025</a>'
  chicago: 'Sazanov, Leonid A. “Structure of Respiratory Complex I: ‘Minimal’ Bacterial
    and ‘de Luxe’ Mammalian Versions.” In <i>Mechanisms of Primary Energy Transduction
    in Biology </i>, edited by Mårten Wikström, 25–59. Mechanisms of Primary Energy
    Transduction in Biology . Royal Society of Chemistry, 2017. <a href="https://doi.org/10.1039/9781788010405-00025">https://doi.org/10.1039/9781788010405-00025</a>.'
  ieee: 'L. A. Sazanov, “Structure of respiratory complex I: ‘Minimal’ bacterial and
    ‘de luxe’ mammalian versions,” in <i>Mechanisms of primary energy transduction
    in biology </i>, M. Wikström, Ed. Royal Society of Chemistry, 2017, pp. 25–59.'
  ista: 'Sazanov LA. 2017.Structure of respiratory complex I: “Minimal” bacterial
    and “de luxe” mammalian versions. In: Mechanisms of primary energy transduction
    in biology . , 25–59.'
  mla: 'Sazanov, Leonid A. “Structure of Respiratory Complex I: ‘Minimal’ Bacterial
    and ‘de Luxe’ Mammalian Versions.” <i>Mechanisms of Primary Energy Transduction
    in Biology </i>, edited by Mårten Wikström, Royal Society of Chemistry, 2017,
    pp. 25–59, doi:<a href="https://doi.org/10.1039/9781788010405-00025">10.1039/9781788010405-00025</a>.'
  short: L.A. Sazanov, in:, M. Wikström (Ed.), Mechanisms of Primary Energy Transduction
    in Biology , Royal Society of Chemistry, 2017, pp. 25–59.
corr_author: '1'
date_created: 2018-12-11T11:46:30Z
date_published: 2017-11-29T00:00:00Z
date_updated: 2024-10-09T20:58:14Z
day: '29'
department:
- _id: LeSa
doi: 10.1039/9781788010405-00025
editor:
- first_name: Mårten
  full_name: Wikström, Mårten
  last_name: Wikström
language:
- iso: eng
month: '11'
oa_version: None
page: 25 - 59
publication: 'Mechanisms of primary energy transduction in biology '
publication_identifier:
  isbn:
  - 978-1-78262-865-1
publication_status: published
publisher: Royal Society of Chemistry
publist_id: '7379'
quality_controlled: '1'
series_title: 'Mechanisms of Primary Energy Transduction in Biology '
status: public
title: 'Structure of respiratory complex I: “Minimal” bacterial and “de luxe” mammalian
  versions'
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2017'
...
---
_id: '445'
abstract:
- lang: eng
  text: The Loschmidt echo, defined as the overlap between quantum wave function evolved
    with different Hamiltonians, quantifies the sensitivity of quantum dynamics to
    perturbations and is often used as a probe of quantum chaos. In this work we consider
    the behavior of the Loschmidt echo in the many-body localized phase, which is
    characterized by emergent local integrals of motion and provides a generic example
    of nonergodic dynamics. We demonstrate that the fluctuations of the Loschmidt
    echo decay as a power law in time in the many-body localized phase, in contrast
    to the exponential decay in few-body ergodic systems. We consider the spin-echo
    generalization of the Loschmidt echo and argue that the corresponding correlation
    function saturates to a finite value in localized systems. Slow, power-law decay
    of fluctuations of such spin-echo-type overlap is related to the operator spreading
    and is present only in the many-body localized phase, but not in a noninteracting
    Anderson insulator. While most of the previously considered probes of dephasing
    dynamics could be understood by approximating physical spin operators with local
    integrals of motion, the Loschmidt echo and its generalizations crucially depend
    on the full expansion of the physical operators via local integrals of motion
    operators, as well as operators which flip local integrals of motion. Hence these
    probes allow one to get insights into the relation between physical operators
    and local integrals of motion and access the operator spreading in the many-body
    localized phase.
acknowledgement: "This research was supported in part by the National\r\nScience Foundation
  under Grant No. NSF PHY11-25915.\r\nM.S. was supported by Gordon and Betty Moore
  Foundation’s\r\nEPiQS Initiative through Grant No. GBMF4307. D.A. also\r\nacknowledges
  support by Swiss National Science Foundation."
article_processing_charge: No
arxiv: 1
author:
- first_name: Maksym
  full_name: Serbyn, Maksym
  id: 47809E7E-F248-11E8-B48F-1D18A9856A87
  last_name: Serbyn
  orcid: 0000-0002-2399-5827
- first_name: Dimitry
  full_name: Abanin, Dimitry
  last_name: Abanin
citation:
  ama: Serbyn M, Abanin D. Loschmidt echo in many body localized phases. <i>Physical
    Review B - Condensed Matter and Materials Physics</i>. 2017;96(1). doi:<a href="https://doi.org/10.1103/PhysRevB.96.014202">10.1103/PhysRevB.96.014202</a>
  apa: Serbyn, M., &#38; Abanin, D. (2017). Loschmidt echo in many body localized
    phases. <i>Physical Review B - Condensed Matter and Materials Physics</i>. American
    Physical Society. <a href="https://doi.org/10.1103/PhysRevB.96.014202">https://doi.org/10.1103/PhysRevB.96.014202</a>
  chicago: Serbyn, Maksym, and Dimitry Abanin. “Loschmidt Echo in Many Body Localized
    Phases.” <i>Physical Review B - Condensed Matter and Materials Physics</i>. American
    Physical Society, 2017. <a href="https://doi.org/10.1103/PhysRevB.96.014202">https://doi.org/10.1103/PhysRevB.96.014202</a>.
  ieee: M. Serbyn and D. Abanin, “Loschmidt echo in many body localized phases,” <i>Physical
    Review B - Condensed Matter and Materials Physics</i>, vol. 96, no. 1. American
    Physical Society, 2017.
  ista: Serbyn M, Abanin D. 2017. Loschmidt echo in many body localized phases. Physical
    Review B - Condensed Matter and Materials Physics. 96(1).
  mla: Serbyn, Maksym, and Dimitry Abanin. “Loschmidt Echo in Many Body Localized
    Phases.” <i>Physical Review B - Condensed Matter and Materials Physics</i>, vol.
    96, no. 1, American Physical Society, 2017, doi:<a href="https://doi.org/10.1103/PhysRevB.96.014202">10.1103/PhysRevB.96.014202</a>.
  short: M. Serbyn, D. Abanin, Physical Review B - Condensed Matter and Materials
    Physics 96 (2017).
date_created: 2018-12-11T11:46:31Z
date_published: 2017-07-12T00:00:00Z
date_updated: 2025-09-04T06:59:31Z
day: '12'
doi: 10.1103/PhysRevB.96.014202
extern: '1'
external_id:
  arxiv:
  - '1701.07772'
intvolume: '        96'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1701.07772
month: '07'
oa: 1
oa_version: Preprint
publication: Physical Review B - Condensed Matter and Materials Physics
publication_status: published
publisher: American Physical Society
publist_id: '7378'
status: public
title: Loschmidt echo in many body localized phases
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 96
year: '2017'
...
---
_id: '447'
abstract:
- lang: eng
  text: We consider last passage percolation (LPP) models with exponentially distributed
    random variables, which are linked to the totally asymmetric simple exclusion
    process (TASEP). The competition interface for LPP was introduced and studied
    in Ferrari and Pimentel (2005a) for cases where the corresponding exclusion process
    had a rarefaction fan. Here we consider situations with a shock and determine
    the law of the fluctuations of the competition interface around its deter- ministic
    law of large number position. We also study the multipoint distribution of the
    LPP around the shock, extending our one-point result of Ferrari and Nejjar (2015).
article_processing_charge: No
article_type: original
author:
- first_name: Patrik
  full_name: Ferrari, Patrik
  last_name: Ferrari
- first_name: Peter
  full_name: Nejjar, Peter
  id: 4BF426E2-F248-11E8-B48F-1D18A9856A87
  last_name: Nejjar
citation:
  ama: Ferrari P, Nejjar P. Fluctuations of the competition interface in presence
    of shocks. <i>Revista Latino-Americana de Probabilidade e Estatística</i>. 2017;9:299-325.
    doi:<a href="https://doi.org/10.30757/ALEA.v14-17">10.30757/ALEA.v14-17</a>
  apa: Ferrari, P., &#38; Nejjar, P. (2017). Fluctuations of the competition interface
    in presence of shocks. <i>Revista Latino-Americana de Probabilidade e Estatística</i>.
    Instituto Nacional de Matematica Pura e Aplicada. <a href="https://doi.org/10.30757/ALEA.v14-17">https://doi.org/10.30757/ALEA.v14-17</a>
  chicago: Ferrari, Patrik, and Peter Nejjar. “Fluctuations of the Competition Interface
    in Presence of Shocks.” <i>Revista Latino-Americana de Probabilidade e Estatística</i>.
    Instituto Nacional de Matematica Pura e Aplicada, 2017. <a href="https://doi.org/10.30757/ALEA.v14-17">https://doi.org/10.30757/ALEA.v14-17</a>.
  ieee: P. Ferrari and P. Nejjar, “Fluctuations of the competition interface in presence
    of shocks,” <i>Revista Latino-Americana de Probabilidade e Estatística</i>, vol.
    9. Instituto Nacional de Matematica Pura e Aplicada, pp. 299–325, 2017.
  ista: Ferrari P, Nejjar P. 2017. Fluctuations of the competition interface in presence
    of shocks. Revista Latino-Americana de Probabilidade e Estatística. 9, 299–325.
  mla: Ferrari, Patrik, and Peter Nejjar. “Fluctuations of the Competition Interface
    in Presence of Shocks.” <i>Revista Latino-Americana de Probabilidade e Estatística</i>,
    vol. 9, Instituto Nacional de Matematica Pura e Aplicada, 2017, pp. 299–325, doi:<a
    href="https://doi.org/10.30757/ALEA.v14-17">10.30757/ALEA.v14-17</a>.
  short: P. Ferrari, P. Nejjar, Revista Latino-Americana de Probabilidade e Estatística
    9 (2017) 299–325.
corr_author: '1'
date_created: 2018-12-11T11:46:31Z
date_published: 2017-03-23T00:00:00Z
date_updated: 2025-09-18T10:02:36Z
day: '23'
department:
- _id: LaEr
- _id: JaMa
doi: 10.30757/ALEA.v14-17
ec_funded: 1
external_id:
  isi:
  - '000404011700017'
intvolume: '         9'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://alea.impa.br/articles/v14/14-17.pdf
month: '03'
oa: 1
oa_version: Submitted Version
page: 299 - 325
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '338804'
  name: Random matrices, universality and disordered quantum systems
publication: Revista Latino-Americana de Probabilidade e Estatística
publication_status: published
publisher: Instituto Nacional de Matematica Pura e Aplicada
publist_id: '7376'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Fluctuations of the competition interface in presence of shocks
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 9
year: '2017'
...
---
_id: '452'
abstract:
- lang: eng
  text: 'Spinning tops and yo-yos have long fascinated cultures around the world with
    their unexpected, graceful motions that seemingly elude gravity. Yet, due to the
    exceeding difficulty of creating stably spinning objects of asymmetric shape in
    a manual trial-and-error process, there has been little departure from rotationally
    symmetric designs. With modern 3D printing technologies, however, we can manufacture
    shapes of almost unbounded complexity at the press of a button, shifting this
    design complexity toward computation. In this article, we describe an algorithm
    to generate designs for spinning objects by optimizing their mass distribution:
    as input, the user provides a solid 3D model and a desired axis of rotation. Our
    approach then modifies the interior mass distribution such that the principal
    directions of the moment of inertia align with the target rotation frame. To create
    voids inside the model, we represent its volume with an adaptive multiresolution
    voxelization and optimize the discrete voxel fill values using a continuous, nonlinear
    formulation. We further optimize for rotational stability by maximizing the dominant
    principal moment. Our method is well-suited for a variety of 3D printed models,
    ranging from characters to abstract shapes. We demonstrate tops and yo-yos that
    spin surprisingly stably despite their asymmetric appearance.'
acknowledgement: "This project was supported in part by the ERC Starting Grant iModel
  (StG-2012-306877). Emily Whiting was supported by the ETH Zurich/Marie Curie COFUND
  Postdoctoral Fellowship. \r\nFirst and foremost, we would like to thank our editor
  Steve Marschner for his invaluable feedback. We were fortunate to get further help
  from Maurizio Nitti for model design, Romain Prévost for Make-It-Stand comparisons,
  Alexander Sorkine-Hornung, Kaan Yücer, and Changil Kim for video and photo assistance,
  Ronnie Gänsli for metal casting, Alec Jacobson for the posed Elephant and Armadillo
  models, and Romain Prévost and Amit Bermano for print preparation. Model sources
  include: Woven Ring: generated by “Sculpture Generator 1” by Carlo H. Séquin, UC
  Berkeley; Elephant: De Espona model library, courtesy of Robert Sumner; T-Rex: TurboSquid;
  Armadillo: Stanford Computer Graphics Laboratory; and Utah Teapot: Martin Newell,
  University of Utah. "
article_processing_charge: No
article_type: original
author:
- first_name: Moritz
  full_name: Bächer, Moritz
  last_name: Bächer
- first_name: Bernd
  full_name: Bickel, Bernd
  id: 49876194-F248-11E8-B48F-1D18A9856A87
  last_name: Bickel
  orcid: 0000-0001-6511-9385
- first_name: Emily
  full_name: Whiting, Emily
  last_name: Whiting
- first_name: Olga
  full_name: Sorkine Hornung, Olga
  last_name: Sorkine Hornung
citation:
  ama: 'Bächer M, Bickel B, Whiting E, Sorkine Hornung O. Spin it: Optimizing moment
    of inertia for spinnable objects. <i>Communications of the ACM</i>. 2017;60(8):92-99.
    doi:<a href="https://doi.org/10.1145/3068766">10.1145/3068766</a>'
  apa: 'Bächer, M., Bickel, B., Whiting, E., &#38; Sorkine Hornung, O. (2017). Spin
    it: Optimizing moment of inertia for spinnable objects. <i>Communications of the
    ACM</i>. ACM. <a href="https://doi.org/10.1145/3068766">https://doi.org/10.1145/3068766</a>'
  chicago: 'Bächer, Moritz, Bernd Bickel, Emily Whiting, and Olga Sorkine Hornung.
    “Spin It: Optimizing Moment of Inertia for Spinnable Objects.” <i>Communications
    of the ACM</i>. ACM, 2017. <a href="https://doi.org/10.1145/3068766">https://doi.org/10.1145/3068766</a>.'
  ieee: 'M. Bächer, B. Bickel, E. Whiting, and O. Sorkine Hornung, “Spin it: Optimizing
    moment of inertia for spinnable objects,” <i>Communications of the ACM</i>, vol.
    60, no. 8. ACM, pp. 92–99, 2017.'
  ista: 'Bächer M, Bickel B, Whiting E, Sorkine Hornung O. 2017. Spin it: Optimizing
    moment of inertia for spinnable objects. Communications of the ACM. 60(8), 92–99.'
  mla: 'Bächer, Moritz, et al. “Spin It: Optimizing Moment of Inertia for Spinnable
    Objects.” <i>Communications of the ACM</i>, vol. 60, no. 8, ACM, 2017, pp. 92–99,
    doi:<a href="https://doi.org/10.1145/3068766">10.1145/3068766</a>.'
  short: M. Bächer, B. Bickel, E. Whiting, O. Sorkine Hornung, Communications of the
    ACM 60 (2017) 92–99.
date_created: 2018-12-11T11:46:33Z
date_published: 2017-08-01T00:00:00Z
date_updated: 2025-08-05T14:20:24Z
day: '01'
department:
- _id: BeBi
doi: 10.1145/3068766
intvolume: '        60'
issue: '8'
language:
- iso: eng
month: '08'
oa_version: None
page: 92 - 99
publication: Communications of the ACM
publication_status: published
publisher: ACM
publist_id: '7370'
quality_controlled: '1'
related_material:
  record:
  - id: '2080'
    relation: earlier_version
    status: public
scopus_import: '1'
status: public
title: 'Spin it: Optimizing moment of inertia for spinnable objects'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 60
year: '2017'
...
