---
OA_type: closed access
_id: '22581'
abstract:
- lang: eng
  text: This study contributes to the understanding of the relationship between air
    temperature and convection by analyzing the characteristics of rainfall at the
    storm and convective rain cell scales. High spatial–temporal resolution (1 km,
    5 min) estimates from a uniquely long weather radar record (24 years) were coupled
    with near-surface air temperature over Mediterranean and semiarid regions in the
    eastern Mediterranean. In the examined temperature range (5°–25°C), the peak intensity
    of individual convective rain cells was found to increase with temperature, but
    at a lower rate than the 7%°C−1 scaling expected from the Clausius–Clapeyron relation,
    while the area of the individual convective rain cells slightly decreases or,
    at most, remains unchanged. At the storm scale, the areal convective rainfall
    was found to increase with warmer temperatures, whereas the areal nonconvective
    rainfall and the stormwide area decrease. This suggests an enhanced moisture convergence
    from the stormwide extent toward the convective rain cells. Results indicate a
    reduction in the total rainfall amounts and an increased heterogeneity of the
    spatial structure of the storm rainfall for temperatures increasing up to 25°C.
    Thermodynamic conditions, analyzed using convective available potential energy,
    were determined to be similar between Mediterranean and semiarid regions. Limitations
    in the atmospheric moisture availability when shifting from Mediterranean to semiarid
    climates were detected and explain the suppression of the intensity of the convective
    rain cells when moving toward drier regions. The relationships obtained in this
    study are relevant for nearby regions characterized by Mediterranean and semiarid
    climates.
article_processing_charge: No
article_type: original
author:
- first_name: Nadav
  full_name: Peleg, Nadav
  last_name: Peleg
- first_name: Francesco
  full_name: Marra, Francesco
  last_name: Marra
- first_name: Simone
  full_name: Fatichi, Simone
  id: cf8e546b-a9b0-11f0-a43b-aa89ed1b56d6
  last_name: Fatichi
- first_name: Peter
  full_name: Molnar, Peter
  last_name: Molnar
- first_name: Efrat
  full_name: Morin, Efrat
  last_name: Morin
- first_name: Ashish
  full_name: Sharma, Ashish
  last_name: Sharma
- first_name: Paolo
  full_name: Burlando, Paolo
  last_name: Burlando
citation:
  ama: Peleg N, Marra F, Fatichi S, et al. Intensification of convective rain cells
    at warmer temperatures observed from high-resolution weather radar data. <i>Journal
    of Hydrometeorology</i>. 2018;19(4):715-726. doi:<a href="https://doi.org/10.1175/jhm-d-17-0158.1">10.1175/jhm-d-17-0158.1</a>
  apa: Peleg, N., Marra, F., Fatichi, S., Molnar, P., Morin, E., Sharma, A., &#38;
    Burlando, P. (2018). Intensification of convective rain cells at warmer temperatures
    observed from high-resolution weather radar data. <i>Journal of Hydrometeorology</i>.
    American Meteorological Society. <a href="https://doi.org/10.1175/jhm-d-17-0158.1">https://doi.org/10.1175/jhm-d-17-0158.1</a>
  chicago: Peleg, Nadav, Francesco Marra, Simone Fatichi, Peter Molnar, Efrat Morin,
    Ashish Sharma, and Paolo Burlando. “Intensification of Convective Rain Cells at
    Warmer Temperatures Observed from High-Resolution Weather Radar Data.” <i>Journal
    of Hydrometeorology</i>. American Meteorological Society, 2018. <a href="https://doi.org/10.1175/jhm-d-17-0158.1">https://doi.org/10.1175/jhm-d-17-0158.1</a>.
  ieee: N. Peleg <i>et al.</i>, “Intensification of convective rain cells at warmer
    temperatures observed from high-resolution weather radar data,” <i>Journal of
    Hydrometeorology</i>, vol. 19, no. 4. American Meteorological Society, pp. 715–726,
    2018.
  ista: Peleg N, Marra F, Fatichi S, Molnar P, Morin E, Sharma A, Burlando P. 2018.
    Intensification of convective rain cells at warmer temperatures observed from
    high-resolution weather radar data. Journal of Hydrometeorology. 19(4), 715–726.
  mla: Peleg, Nadav, et al. “Intensification of Convective Rain Cells at Warmer Temperatures
    Observed from High-Resolution Weather Radar Data.” <i>Journal of Hydrometeorology</i>,
    vol. 19, no. 4, American Meteorological Society, 2018, pp. 715–26, doi:<a href="https://doi.org/10.1175/jhm-d-17-0158.1">10.1175/jhm-d-17-0158.1</a>.
  short: N. Peleg, F. Marra, S. Fatichi, P. Molnar, E. Morin, A. Sharma, P. Burlando,
    Journal of Hydrometeorology 19 (2018) 715–726.
das_tickbox: '1'
date_created: 2026-07-27T12:30:25Z
date_published: 2018-04-01T00:00:00Z
date_updated: 2026-08-12T07:50:18Z
day: '01'
doi: 10.1175/jhm-d-17-0158.1
extern: '1'
fulldoi: https://doi.org/10.1175/jhm-d-17-0158.1
intvolume: '        19'
issue: '4'
language:
- iso: eng
month: '04'
oa_version: None
page: 715-726
publication: Journal of Hydrometeorology
publication_identifier:
  eissn:
  - 1525-7541
  issn:
  - 1525-755X
publication_status: published
publisher: American Meteorological Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Intensification of convective rain cells at warmer temperatures observed from
  high-resolution weather radar data
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 19
year: '2018'
...
---
_id: '5980'
abstract:
- lang: eng
  text: The problem of private set-intersection (PSI) has been traditionally treated
    as an instance of the more general problem of multi-party computation (MPC). Consequently,
    in order to argue security, or compose these protocols one has to rely on the
    general theory that was developed for the purpose of MPC. The pursuit of efficient
    protocols, however, has resulted in designs that exploit properties pertaining
    to PSI. In almost all practical applications where a PSI protocol is deployed,
    it is expected to be executed multiple times, possibly on related inputs. In this
    work we initiate a dedicated study of PSI in the multi-interaction (MI) setting.
    In this model a server sets up the common system parameters and executes set-intersection
    multiple times with potentially different clients. We discuss a few attacks that
    arise when protocols are naïvely composed in this manner and, accordingly, craft
    security definitions for the MI setting and study their inter-relation. Finally,
    we suggest a set of protocols that are MI-secure, at the same time almost as efficient
    as their parent, stand-alone, protocols.
article_processing_charge: No
author:
- first_name: Sanjit
  full_name: Chatterjee, Sanjit
  last_name: Chatterjee
- first_name: Chethan
  full_name: Kamath Hosdurg, Chethan
  id: 4BD3F30E-F248-11E8-B48F-1D18A9856A87
  last_name: Kamath Hosdurg
  orcid: 0009-0006-6812-7317
- first_name: Vikas
  full_name: Kumar, Vikas
  last_name: Kumar
citation:
  ama: Chatterjee S, Kamath Hosdurg C, Kumar V. Private set-intersection with common
    set-up. <i>Advances in Mathematics of Communications</i>. 2018;12(1):17-47. doi:<a
    href="https://doi.org/10.3934/amc.2018002">10.3934/amc.2018002</a>
  apa: Chatterjee, S., Kamath Hosdurg, C., &#38; Kumar, V. (2018). Private set-intersection
    with common set-up. <i>Advances in Mathematics of Communications</i>. AIMS. <a
    href="https://doi.org/10.3934/amc.2018002">https://doi.org/10.3934/amc.2018002</a>
  chicago: Chatterjee, Sanjit, Chethan Kamath Hosdurg, and Vikas Kumar. “Private Set-Intersection
    with Common Set-Up.” <i>Advances in Mathematics of Communications</i>. AIMS, 2018.
    <a href="https://doi.org/10.3934/amc.2018002">https://doi.org/10.3934/amc.2018002</a>.
  ieee: S. Chatterjee, C. Kamath Hosdurg, and V. Kumar, “Private set-intersection
    with common set-up,” <i>Advances in Mathematics of Communications</i>, vol. 12,
    no. 1. AIMS, pp. 17–47, 2018.
  ista: Chatterjee S, Kamath Hosdurg C, Kumar V. 2018. Private set-intersection with
    common set-up. Advances in Mathematics of Communications. 12(1), 17–47.
  mla: Chatterjee, Sanjit, et al. “Private Set-Intersection with Common Set-Up.” <i>Advances
    in Mathematics of Communications</i>, vol. 12, no. 1, AIMS, 2018, pp. 17–47, doi:<a
    href="https://doi.org/10.3934/amc.2018002">10.3934/amc.2018002</a>.
  short: S. Chatterjee, C. Kamath Hosdurg, V. Kumar, Advances in Mathematics of Communications
    12 (2018) 17–47.
date_created: 2019-02-13T13:49:41Z
date_published: 2018-02-01T00:00:00Z
date_updated: 2026-08-12T09:13:26Z
day: '01'
department:
- _id: KrPi
doi: 10.3934/amc.2018002
external_id:
  isi:
  - '000430950400002'
fulldoi: https://doi.org/10.3934/amc.2018002
intvolume: '        12'
isi: 1
issue: '1'
language:
- iso: eng
month: '02'
oa_version: None
page: 17-47
publication: Advances in Mathematics of Communications
publication_identifier:
  issn:
  - 1930-5346
publication_status: published
publisher: AIMS
quality_controlled: '1'
scopus_import: '1'
status: public
title: Private set-intersection with common set-up
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2018'
...
---
OA_place: publisher
_id: '418'
abstract:
- lang: eng
  text: "The aim of this thesis was the development of new strategies for optical
    and optogenetic control of proliferative and pro-survival signaling, and characterizing
    them from the molecular mechanism up to cellular effects. These new light-based
    methods have unique features, such as red light as an activator, or the avoidance
    of gene delivery, which enable to overcome current limitations, such as light
    delivery to target tissues and feasibility as therapeutic approach. A special
    focus was placed on implementing these new light-based approaches in pancreatic
    β-cells, as β-cells are the key players in diabetes and especially their loss
    in number negatively affects disease progression. Currently no treatment options
    are available to compensate the lack of functional β-cells in diabetic patients.\r\nIn
    a first approach, red-light-activated growth factor receptors, in particular receptor
    tyrosine kinases were engineered and characterized. Receptor activation with light
    allows spatio-temporal control compared to ligand-based activation, and especially
    red light exhibits deeper tissue penetration than other wavelengths of the visible
    spectrum. Red-light-activated receptor tyrosine kinases robustly activated major
    growth factor related signaling pathways with a high temporal resolution. Moreover,
    the remote activation of the proliferative MAPK/Erk pathway by red-light-activated
    receptor tyrosine kinases in a pancreatic β-cell line was also achieved, through
    one centimeter thick mouse tissue. Although red-light-activated receptor tyrosine
    kinases are particularly attractive for applications in animal models due to the
    deep tissue penetration of red light, a drawback, especially with regard to translation
    into humans, is the requirement of gene therapy.\r\nIn a second approach an endogenous
    light-sensitive mechanism was identified and its potential to promote proliferative
    and pro-survival signals was explored, towards light-based tissue regeneration
    without the need for gene transfer. Blue-green light illumination was found to
    be sufficient for the activation of proliferation and survival promoting signaling
    pathways in primary pancreatic murine and human islets. Blue-green light also
    led to an increase in proliferation of primary islet cells, an effect which was
    shown to be mostly β-cell specific in human islets. Moreover, it was demonstrated
    that this approach of pancreatic β-cell expansion did not have any negative effect
    on the β-cell function, in particular on their insulin secretion capacity. In
    contrast, a trend for enhanced insulin secretion under high glucose conditions
    after illumination was detected. In order to unravel the detailed characteristics
    of this endogenous light-sensitive mechanism, the precise light requirements were
    determined. In addition, the expression of light sensing proteins, OPN3 and rhodopsin,
    was detected. The observed effects were found to be independent of handling effects
    such as temperature differences and cytochrome c oxidase dependent ATP increase,
    but they were found to be enhanced through the knockout of OPN3. The exact mechanism
    of how islets cells sense light and the identity of the photoreceptor remains
    unknown.\r\nSummarized two new light-based systems with unique features were established
    that enable the activation of proliferative and pro-survival signaling pathways.
    While red-light-activated receptor tyrosine kinases open a new avenue for optogenetics
    research, by allowing non-invasive control of signaling in vivo, the identified
    endogenous light-sensitive mechanism has the potential to be the basis of a gene
    therapy-free therapeutical approach for light-based β-cell expansion."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Eva
  full_name: Gschaider-Reichhart, Eva
  id: 3FEE232A-F248-11E8-B48F-1D18A9856A87
  last_name: Gschaider-Reichhart
  orcid: 0000-0002-7218-7738
citation:
  ama: Gschaider-Reichhart E. Optical and optogenetic control of proliferation and
    survival . 2018. doi:<a href="https://doi.org/10.15479/AT:ISTA:th_913">10.15479/AT:ISTA:th_913</a>
  apa: Gschaider-Reichhart, E. (2018). <i>Optical and optogenetic control of proliferation
    and survival </i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:th_913">https://doi.org/10.15479/AT:ISTA:th_913</a>
  chicago: Gschaider-Reichhart, Eva. “Optical and Optogenetic Control of Proliferation
    and Survival .” Institute of Science and Technology Austria, 2018. <a href="https://doi.org/10.15479/AT:ISTA:th_913">https://doi.org/10.15479/AT:ISTA:th_913</a>.
  ieee: E. Gschaider-Reichhart, “Optical and optogenetic control of proliferation
    and survival ,” Institute of Science and Technology Austria, 2018.
  ista: Gschaider-Reichhart E. 2018. Optical and optogenetic control of proliferation
    and survival . Institute of Science and Technology Austria.
  mla: Gschaider-Reichhart, Eva. <i>Optical and Optogenetic Control of Proliferation
    and Survival </i>. Institute of Science and Technology Austria, 2018, doi:<a href="https://doi.org/10.15479/AT:ISTA:th_913">10.15479/AT:ISTA:th_913</a>.
  short: E. Gschaider-Reichhart, Optical and Optogenetic Control of Proliferation
    and Survival , Institute of Science and Technology Austria, 2018.
corr_author: '1'
date_created: 2018-12-11T11:46:22Z
date_published: 2018-01-08T00:00:00Z
date_updated: 2026-08-12T09:19:21Z
day: '08'
ddc:
- '571'
- '570'
degree_awarded: PhD
department:
- _id: HaJa
doi: 10.15479/AT:ISTA:th_913
file:
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has_accepted_license: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: '107'
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '7405'
pubrep_id: '913'
related_material:
  record:
  - id: '1678'
    relation: part_of_dissertation
    status: public
  - id: '2084'
    relation: part_of_dissertation
    status: public
  - id: '1441'
    relation: part_of_dissertation
    status: public
  - id: '1028'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Harald L
  full_name: Janovjak, Harald L
  id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
  last_name: Janovjak
  orcid: 0000-0002-8023-9315
title: 'Optical and optogenetic control of proliferation and survival '
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
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  short: CC BY (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2018'
...
---
OA_place: publisher
_id: '149'
abstract:
- lang: eng
  text: The eigenvalue density of many large random matrices is well approximated
    by a deterministic measure, the self-consistent density of states. In the present
    work, we show this behaviour for several classes of random matrices. In fact,
    we establish that, in each of these classes, the self-consistent density of states
    approximates the eigenvalue density of the random matrix on all scales slightly
    above the typical eigenvalue spacing. For large classes of random matrices, the
    self-consistent density of states exhibits several universal features. We prove
    that, under suitable assumptions, random Gram matrices and Hermitian random matrices
    with decaying correlations have a 1/3-Hölder continuous self-consistent density
    of states ρ on R, which is analytic, where it is positive, and has either a square
    root edge or a cubic root cusp, where it vanishes. We, thus, extend the validity
    of the corresponding result for Wigner-type matrices from [4, 5, 7]. We show that
    ρ is determined as the inverse Stieltjes transform of the normalized trace of
    the unique solution m(z) to the Dyson equation −m(z) −1 = z − a + S[m(z)] on C
    N×N with the constraint Im m(z) ≥ 0. Here, z lies in the complex upper half-plane,
    a is a self-adjoint element of C N×N and S is a positivity-preserving operator
    on C N×N encoding the first two moments of the random matrix. In order to analyze
    a possible limit of ρ for N → ∞ and address some applications in free probability
    theory, we also consider the Dyson equation on infinite dimensional von Neumann
    algebras. We present two applications to random matrices. We first establish that,
    under certain assumptions, large random matrices with independent entries have
    a rotationally symmetric self-consistent density of states which is supported
    on a centered disk in C. Moreover, it is infinitely often differentiable apart
    from a jump on the boundary of this disk. Second, we show edge universality at
    all regular (not necessarily extreme) spectral edges for Hermitian random matrices
    with decaying correlations.
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Johannes
  full_name: Alt, Johannes
  id: 36D3D8B6-F248-11E8-B48F-1D18A9856A87
  last_name: Alt
citation:
  ama: Alt J. Dyson equation and eigenvalue statistics of random matrices. 2018. doi:<a
    href="https://doi.org/10.15479/AT:ISTA:TH_1040">10.15479/AT:ISTA:TH_1040</a>
  apa: Alt, J. (2018). <i>Dyson equation and eigenvalue statistics of random matrices</i>.
    Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:TH_1040">https://doi.org/10.15479/AT:ISTA:TH_1040</a>
  chicago: Alt, Johannes. “Dyson Equation and Eigenvalue Statistics of Random Matrices.”
    Institute of Science and Technology Austria, 2018. <a href="https://doi.org/10.15479/AT:ISTA:TH_1040">https://doi.org/10.15479/AT:ISTA:TH_1040</a>.
  ieee: J. Alt, “Dyson equation and eigenvalue statistics of random matrices,” Institute
    of Science and Technology Austria, 2018.
  ista: Alt J. 2018. Dyson equation and eigenvalue statistics of random matrices.
    Institute of Science and Technology Austria.
  mla: Alt, Johannes. <i>Dyson Equation and Eigenvalue Statistics of Random Matrices</i>.
    Institute of Science and Technology Austria, 2018, doi:<a href="https://doi.org/10.15479/AT:ISTA:TH_1040">10.15479/AT:ISTA:TH_1040</a>.
  short: J. Alt, Dyson Equation and Eigenvalue Statistics of Random Matrices, Institute
    of Science and Technology Austria, 2018.
corr_author: '1'
date_created: 2018-12-11T11:44:53Z
date_published: 2018-07-12T00:00:00Z
date_updated: 2026-08-12T13:58:56Z
day: '12'
ddc:
- '515'
- '519'
degree_awarded: PhD
department:
- _id: LaEr
doi: 10.15479/AT:ISTA:TH_1040
ec_funded: 1
file:
- access_level: open_access
  checksum: d4dad55a7513f345706aaaba90cb1bb8
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  date_created: 2019-04-08T13:55:20Z
  date_updated: 2020-07-14T12:44:57Z
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  file_name: 2018_thesis_Alt.pdf
  file_size: 5801709
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  content_type: application/zip
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  date_created: 2019-04-08T13:55:20Z
  date_updated: 2020-07-14T12:44:57Z
  file_id: '6242'
  file_name: 2018_thesis_Alt_source.zip
  file_size: 3802059
  relation: source_file
file_date_updated: 2020-07-14T12:44:57Z
fulldoi: https://doi.org/10.15479/AT:ISTA:TH_1040
has_accepted_license: '1'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: '456'
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '338804'
  name: Random matrices, universality and disordered quantum systems
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '7772'
pubrep_id: '1040'
related_material:
  record:
  - id: '6184'
    relation: part_of_dissertation
    status: public
  - id: '6183'
    relation: part_of_dissertation
    status: public
  - id: '1010'
    relation: part_of_dissertation
    status: public
  - id: '550'
    relation: part_of_dissertation
    status: public
  - id: '6240'
    relation: part_of_dissertation
    status: public
  - id: '566'
    relation: part_of_dissertation
    status: public
  - id: '1677'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
title: Dyson equation and eigenvalue statistics of random matrices
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2018'
...
---
_id: '198'
abstract:
- lang: eng
  text: We consider a class of students learning a language from a teacher. The situation
    can be interpreted as a group of child learners receiving input from the linguistic
    environment. The teacher provides sample sentences. The students try to learn
    the grammar from the teacher. In addition to just listening to the teacher, the
    students can also communicate with each other. The students hold hypotheses about
    the grammar and change them if they receive counter evidence. The process stops
    when all students have converged to the correct grammar. We study how the time
    to convergence depends on the structure of the classroom by introducing and evaluating
    various complexity measures. We find that structured communication between students,
    although potentially introducing confusion, can greatly reduce some of the complexity
    measures. Our theory can also be interpreted as applying to the scientific process,
    where nature is the teacher and the scientists are the students.
article_number: '20180073'
article_processing_charge: No
article_type: original
author:
- first_name: Rasmus
  full_name: Ibsen-Jensen, Rasmus
  id: 3B699956-F248-11E8-B48F-1D18A9856A87
  last_name: Ibsen-Jensen
  orcid: 0000-0003-4783-0389
- first_name: Josef
  full_name: Tkadlec, Josef
  id: 3F24CCC8-F248-11E8-B48F-1D18A9856A87
  last_name: Tkadlec
  orcid: 0000-0002-1097-9684
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Martin
  full_name: Nowak, Martin
  last_name: Nowak
citation:
  ama: Ibsen-Jensen R, Tkadlec J, Chatterjee K, Nowak M. Language acquisition with
    communication between learners. <i>Journal of the Royal Society Interface</i>.
    2018;15(140). doi:<a href="https://doi.org/10.1098/rsif.2018.0073">10.1098/rsif.2018.0073</a>
  apa: Ibsen-Jensen, R., Tkadlec, J., Chatterjee, K., &#38; Nowak, M. (2018). Language
    acquisition with communication between learners. <i>Journal of the Royal Society
    Interface</i>. Royal Society. <a href="https://doi.org/10.1098/rsif.2018.0073">https://doi.org/10.1098/rsif.2018.0073</a>
  chicago: Ibsen-Jensen, Rasmus, Josef Tkadlec, Krishnendu Chatterjee, and Martin
    Nowak. “Language Acquisition with Communication between Learners.” <i>Journal
    of the Royal Society Interface</i>. Royal Society, 2018. <a href="https://doi.org/10.1098/rsif.2018.0073">https://doi.org/10.1098/rsif.2018.0073</a>.
  ieee: R. Ibsen-Jensen, J. Tkadlec, K. Chatterjee, and M. Nowak, “Language acquisition
    with communication between learners,” <i>Journal of the Royal Society Interface</i>,
    vol. 15, no. 140. Royal Society, 2018.
  ista: Ibsen-Jensen R, Tkadlec J, Chatterjee K, Nowak M. 2018. Language acquisition
    with communication between learners. Journal of the Royal Society Interface. 15(140),
    20180073.
  mla: Ibsen-Jensen, Rasmus, et al. “Language Acquisition with Communication between
    Learners.” <i>Journal of the Royal Society Interface</i>, vol. 15, no. 140, 20180073,
    Royal Society, 2018, doi:<a href="https://doi.org/10.1098/rsif.2018.0073">10.1098/rsif.2018.0073</a>.
  short: R. Ibsen-Jensen, J. Tkadlec, K. Chatterjee, M. Nowak, Journal of the Royal
    Society Interface 15 (2018).
date_created: 2018-12-11T11:45:09Z
date_published: 2018-03-01T00:00:00Z
date_updated: 2026-08-12T14:08:29Z
day: '01'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1098/rsif.2018.0073
ec_funded: 1
external_id:
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month: '03'
oa: 1
oa_version: Submitted Version
pmid: 1
project:
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  call_identifier: FP7
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  name: 'Quantitative Graph Games: Theory and Applications'
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publication: Journal of the Royal Society Interface
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publication_status: published
publisher: Royal Society
publist_id: '7715'
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title: Language acquisition with communication between learners
type: journal_article
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volume: 15
year: '2018'
...
---
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_id: '52'
abstract:
- lang: eng
  text: In this thesis we will discuss systems of point interacting fermions, their
    stability and other spectral properties. Whereas for bosons a point interacting
    system is always unstable this ques- tion is more subtle for a gas of two species
    of fermions. In particular the answer depends on the mass ratio between these
    two species. Most of this work will be focused on the N + M model which consists
    of two species of fermions with N, M particles respectively which interact via
    point interactions. We will introduce this model using a formal limit and discuss
    the N + 1 system in more detail. In particular, we will show that for mass ratios
    above a critical one, which does not depend on the particle number, the N + 1
    system is stable. In the context of this model we will prove rigorous versions
    of Tan relations which relate various quantities of the point-interacting model.
    By restricting the N + 1 system to a box we define a finite density model with
    point in- teractions. In the context of this system we will discuss the energy
    change when introducing a point-interacting impurity into a system of non-interacting
    fermions. We will see that this change in energy is bounded independently of the
    particle number and in particular the bound only depends on the density and the
    scattering length. As another special case of the N + M model we will show stability
    of the 2 + 2 model for mass ratios in an interval around one. Further we will
    investigate a different model of point interactions which was discussed before
    in the literature and which is, contrary to the N + M model, not given by a limiting
    procedure but is based on a Dirichlet form. We will show that this system behaves
    trivially in the thermodynamic limit, i.e. the free energy per particle is the
    same as the one of the non-interacting system.
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Thomas
  full_name: Moser, Thomas
  id: 2B5FC9A4-F248-11E8-B48F-1D18A9856A87
  last_name: Moser
citation:
  ama: Moser T. Point interactions in systems of fermions. 2018. doi:<a href="https://doi.org/10.15479/AT:ISTA:th_1043">10.15479/AT:ISTA:th_1043</a>
  apa: Moser, T. (2018). <i>Point interactions in systems of fermions</i>. Institute
    of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:th_1043">https://doi.org/10.15479/AT:ISTA:th_1043</a>
  chicago: Moser, Thomas. “Point Interactions in Systems of Fermions.” Institute of
    Science and Technology Austria, 2018. <a href="https://doi.org/10.15479/AT:ISTA:th_1043">https://doi.org/10.15479/AT:ISTA:th_1043</a>.
  ieee: T. Moser, “Point interactions in systems of fermions,” Institute of Science
    and Technology Austria, 2018.
  ista: Moser T. 2018. Point interactions in systems of fermions. Institute of Science
    and Technology Austria.
  mla: Moser, Thomas. <i>Point Interactions in Systems of Fermions</i>. Institute
    of Science and Technology Austria, 2018, doi:<a href="https://doi.org/10.15479/AT:ISTA:th_1043">10.15479/AT:ISTA:th_1043</a>.
  short: T. Moser, Point Interactions in Systems of Fermions, Institute of Science
    and Technology Austria, 2018.
corr_author: '1'
date_created: 2018-12-11T11:44:22Z
date_published: 2018-09-04T00:00:00Z
date_updated: 2026-08-12T14:12:55Z
day: '04'
ddc:
- '515'
- '530'
- '519'
degree_awarded: PhD
department:
- _id: RoSe
doi: 10.15479/AT:ISTA:th_1043
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has_accepted_license: '1'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: '115'
project:
- _id: 25C878CE-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P27533_N27
  name: Structure of the Excitation Spectrum for Many-Body Quantum Systems
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '8002'
pubrep_id: '1043'
related_material:
  record:
  - id: '5856'
    relation: part_of_dissertation
    status: public
  - id: '741'
    relation: part_of_dissertation
    status: public
  - id: '1198'
    relation: part_of_dissertation
    status: public
  - id: '154'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Robert
  full_name: Seiringer, Robert
  id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
  last_name: Seiringer
  orcid: 0000-0002-6781-0521
title: Point interactions in systems of fermions
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2018'
...
---
_id: '154'
abstract:
- lang: eng
  text: We give a lower bound on the ground state energy of a system of two fermions
    of one species interacting with two fermions of another species via point interactions.
    We show that there is a critical mass ratio m2 ≈ 0.58 such that the system is
    stable, i.e., the energy is bounded from below, for m∈[m2,m2−1]. So far it was
    not known whether this 2 + 2 system exhibits a stable region at all or whether
    the formation of four-body bound states causes an unbounded spectrum for all mass
    ratios, similar to the Thomas effect. Our result gives further evidence for the
    stability of the more general N + M system.
acknowledgement: Open access funding provided by Austrian Science Fund (FWF).
article_number: '19'
article_processing_charge: No
article_type: original
author:
- first_name: Thomas
  full_name: Moser, Thomas
  id: 2B5FC9A4-F248-11E8-B48F-1D18A9856A87
  last_name: Moser
- first_name: Robert
  full_name: Seiringer, Robert
  id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
  last_name: Seiringer
  orcid: 0000-0002-6781-0521
citation:
  ama: Moser T, Seiringer R. Stability of the 2+2 fermionic system with point interactions.
    <i>Mathematical Physics, Analysis and Geometry</i>. 2018;21(3). doi:<a href="https://doi.org/10.1007/s11040-018-9275-3">10.1007/s11040-018-9275-3</a>
  apa: Moser, T., &#38; Seiringer, R. (2018). Stability of the 2+2 fermionic system
    with point interactions. <i>Mathematical Physics, Analysis and Geometry</i>. Springer.
    <a href="https://doi.org/10.1007/s11040-018-9275-3">https://doi.org/10.1007/s11040-018-9275-3</a>
  chicago: Moser, Thomas, and Robert Seiringer. “Stability of the 2+2 Fermionic System
    with Point Interactions.” <i>Mathematical Physics, Analysis and Geometry</i>.
    Springer, 2018. <a href="https://doi.org/10.1007/s11040-018-9275-3">https://doi.org/10.1007/s11040-018-9275-3</a>.
  ieee: T. Moser and R. Seiringer, “Stability of the 2+2 fermionic system with point
    interactions,” <i>Mathematical Physics, Analysis and Geometry</i>, vol. 21, no.
    3. Springer, 2018.
  ista: Moser T, Seiringer R. 2018. Stability of the 2+2 fermionic system with point
    interactions. Mathematical Physics, Analysis and Geometry. 21(3), 19.
  mla: Moser, Thomas, and Robert Seiringer. “Stability of the 2+2 Fermionic System
    with Point Interactions.” <i>Mathematical Physics, Analysis and Geometry</i>,
    vol. 21, no. 3, 19, Springer, 2018, doi:<a href="https://doi.org/10.1007/s11040-018-9275-3">10.1007/s11040-018-9275-3</a>.
  short: T. Moser, R. Seiringer, Mathematical Physics, Analysis and Geometry 21 (2018).
date_created: 2018-12-11T11:44:55Z
date_published: 2018-09-01T00:00:00Z
date_updated: 2026-08-12T14:12:56Z
day: '01'
ddc:
- '530'
department:
- _id: RoSe
doi: 10.1007/s11040-018-9275-3
ec_funded: 1
external_id:
  isi:
  - '000439639700001'
file:
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  checksum: 411c4db5700d7297c9cd8ebc5dd29091
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  file_size: 496973
  relation: main_file
file_date_updated: 2020-07-14T12:45:01Z
fulldoi: https://doi.org/10.1007/s11040-018-9275-3
has_accepted_license: '1'
intvolume: '        21'
isi: 1
issue: '3'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
project:
- _id: 25C6DC12-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '694227'
  name: Analysis of quantum many-body systems
- _id: 25C878CE-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P27533_N27
  name: Structure of the Excitation Spectrum for Many-Body Quantum Systems
- _id: 3AC91DDA-15DF-11EA-824D-93A3E7B544D1
  call_identifier: FWF
  name: FWF Open Access Fund
publication: Mathematical Physics, Analysis and Geometry
publication_identifier:
  eissn:
  - 1572-9656
  issn:
  - 1385-0172
publication_status: published
publisher: Springer
publist_id: '7767'
quality_controlled: '1'
related_material:
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scopus_import: '1'
status: public
title: Stability of the 2+2 fermionic system with point interactions
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 21
year: '2018'
...
---
_id: '6'
abstract:
- lang: eng
  text: Lesion and electrode location verification are traditionally done via histological
    examination of stained brain slices, a time-consuming procedure that requires
    manual estimation. Here, we describe a simple, straightforward method for quantifying
    lesions and locating electrodes in the brain that is less laborious and yields
    more detailed results. Whole brains are stained with osmium tetroxide, embedded
    in resin, and imaged with a micro-CT scanner. The scans result in 3D digital volumes
    of the brains with resolutions and virtual section thicknesses dependent on the
    sample size (12-15 and 5-6 µm per voxel for rat and zebra finch brains, respectively).
    Surface and deep lesions can be characterized, and single tetrodes, tetrode arrays,
    electrolytic lesions, and silicon probes can also be localized. Free and proprietary
    software allows experimenters to examine the sample volume from any plane and
    segment the volume manually or automatically. Because this method generates whole
    brain volume, lesions and electrodes can be quantified to a much higher degree
    than in current methods, which will help standardize comparisons within and across
    studies.
article_processing_charge: No
author:
- first_name: Javier
  full_name: Masís, Javier
  last_name: Masís
- first_name: David
  full_name: Mankus, David
  last_name: Mankus
- first_name: Steffen
  full_name: Wolff, Steffen
  last_name: Wolff
- first_name: Grigori
  full_name: Guitchounts, Grigori
  last_name: Guitchounts
- first_name: Maximilian A
  full_name: Jösch, Maximilian A
  id: 2BD278E6-F248-11E8-B48F-1D18A9856A87
  last_name: Jösch
  orcid: 0000-0002-3937-1330
- first_name: David
  full_name: Cox, David
  last_name: Cox
citation:
  ama: Masís J, Mankus D, Wolff S, Guitchounts G, Jösch MA, Cox D. A micro-CT-based
    method for characterising lesions and locating electrodes in small animal brains.
    <i>Journal of Visualized Experiments</i>. 2018;141. doi:<a href="https://doi.org/10.3791/58585">10.3791/58585</a>
  apa: Masís, J., Mankus, D., Wolff, S., Guitchounts, G., Jösch, M. A., &#38; Cox,
    D. (2018). A micro-CT-based method for characterising lesions and locating electrodes
    in small animal brains. <i>Journal of Visualized Experiments</i>. MyJove Corporation.
    <a href="https://doi.org/10.3791/58585">https://doi.org/10.3791/58585</a>
  chicago: Masís, Javier, David Mankus, Steffen Wolff, Grigori Guitchounts, Maximilian
    A Jösch, and David Cox. “A Micro-CT-Based Method for Characterising Lesions and
    Locating Electrodes in Small Animal Brains.” <i>Journal of Visualized Experiments</i>.
    MyJove Corporation, 2018. <a href="https://doi.org/10.3791/58585">https://doi.org/10.3791/58585</a>.
  ieee: J. Masís, D. Mankus, S. Wolff, G. Guitchounts, M. A. Jösch, and D. Cox, “A
    micro-CT-based method for characterising lesions and locating electrodes in small
    animal brains,” <i>Journal of Visualized Experiments</i>, vol. 141. MyJove Corporation,
    2018.
  ista: Masís J, Mankus D, Wolff S, Guitchounts G, Jösch MA, Cox D. 2018. A micro-CT-based
    method for characterising lesions and locating electrodes in small animal brains.
    Journal of Visualized Experiments. 141.
  mla: Masís, Javier, et al. “A Micro-CT-Based Method for Characterising Lesions and
    Locating Electrodes in Small Animal Brains.” <i>Journal of Visualized Experiments</i>,
    vol. 141, MyJove Corporation, 2018, doi:<a href="https://doi.org/10.3791/58585">10.3791/58585</a>.
  short: J. Masís, D. Mankus, S. Wolff, G. Guitchounts, M.A. Jösch, D. Cox, Journal
    of Visualized Experiments 141 (2018).
date_created: 2018-12-11T11:44:07Z
date_published: 2018-11-08T00:00:00Z
date_updated: 2026-08-12T14:10:17Z
day: '08'
department:
- _id: MaJö
doi: 10.3791/58585
external_id:
  isi:
  - '000456469400103'
fulldoi: https://doi.org/10.3791/58585
intvolume: '       141'
isi: 1
language:
- iso: eng
month: '11'
oa_version: None
publication: Journal of Visualized Experiments
publication_status: published
publisher: MyJove Corporation
publist_id: '8050'
quality_controlled: '1'
scopus_import: '1'
status: public
title: A micro-CT-based method for characterising lesions and locating electrodes
  in small animal brains
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 141
year: '2018'
...
---
_id: '294'
abstract:
- lang: eng
  text: We developed a method to calculate two-photon processes in quantum mechanics
    that replaces the infinite summation over the intermediate states by a perturbation
    expansion. This latter consists of a series of commutators that involve position,
    momentum, and Hamiltonian quantum operators. We analyzed several single- and many-particle
    cases for which a closed-form solution to the perturbation expansion exists, as
    well as more complicated cases for which a solution is found by convergence. Throughout
    the article, Rayleigh and Raman scattering are taken as examples of two-photon
    processes. The present method provides a clear distinction between the Thomson
    scattering, regarded as classical scattering, and quantum contributions. Such
    a distinction lets us derive general results concerning light scattering. Finally,
    possible extensions to the developed formalism are discussed.
article_processing_charge: No
arxiv: 1
author:
- first_name: Filippo
  full_name: Fratini, Filippo
  last_name: Fratini
- first_name: Laleh
  full_name: Safari, Laleh
  id: 3C325E5E-F248-11E8-B48F-1D18A9856A87
  last_name: Safari
- first_name: Pedro
  full_name: Amaro, Pedro
  last_name: Amaro
- first_name: José
  full_name: Santos, José
  last_name: Santos
citation:
  ama: Fratini F, Safari L, Amaro P, Santos J. Two-photon processes based on quantum
    commutators. <i>Physical Review A</i>. 2018;97(4). doi:<a href="https://doi.org/10.1103/PhysRevA.97.043842">10.1103/PhysRevA.97.043842</a>
  apa: Fratini, F., Safari, L., Amaro, P., &#38; Santos, J. (2018). Two-photon processes
    based on quantum commutators. <i>Physical Review A</i>. American Physical Society.
    <a href="https://doi.org/10.1103/PhysRevA.97.043842">https://doi.org/10.1103/PhysRevA.97.043842</a>
  chicago: Fratini, Filippo, Laleh Safari, Pedro Amaro, and José Santos. “Two-Photon
    Processes Based on Quantum Commutators.” <i>Physical Review A</i>. American Physical
    Society, 2018. <a href="https://doi.org/10.1103/PhysRevA.97.043842">https://doi.org/10.1103/PhysRevA.97.043842</a>.
  ieee: F. Fratini, L. Safari, P. Amaro, and J. Santos, “Two-photon processes based
    on quantum commutators,” <i>Physical Review A</i>, vol. 97, no. 4. American Physical
    Society, 2018.
  ista: Fratini F, Safari L, Amaro P, Santos J. 2018. Two-photon processes based on
    quantum commutators. Physical Review A. 97(4).
  mla: Fratini, Filippo, et al. “Two-Photon Processes Based on Quantum Commutators.”
    <i>Physical Review A</i>, vol. 97, no. 4, American Physical Society, 2018, doi:<a
    href="https://doi.org/10.1103/PhysRevA.97.043842">10.1103/PhysRevA.97.043842</a>.
  short: F. Fratini, L. Safari, P. Amaro, J. Santos, Physical Review A 97 (2018).
date_created: 2018-12-11T11:45:40Z
date_published: 2018-04-18T00:00:00Z
date_updated: 2026-08-12T14:22:13Z
day: '18'
department:
- _id: MiLe
doi: 10.1103/PhysRevA.97.043842
ec_funded: 1
external_id:
  arxiv:
  - '1801.06892'
  isi:
  - '000430296800008'
fulldoi: https://doi.org/10.1103/PhysRevA.97.043842
intvolume: '        97'
isi: 1
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1801.06892
month: '04'
oa: 1
oa_version: Submitted Version
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication: Physical Review A
publication_status: published
publisher: American Physical Society
publist_id: '7587'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Two-photon processes based on quantum commutators
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 97
year: '2018'
...
---
_id: '195'
abstract:
- lang: eng
  text: We demonstrate that identical impurities immersed in a two-dimensional many-particle
    bath can be viewed as flux-tube-charged-particle composites described by fractional
    statistics. In particular, we find that the bath manifests itself as an external
    magnetic flux tube with respect to the impurities, and hence the time-reversal
    symmetry is broken for the effective Hamiltonian describing the impurities. The
    emerging flux tube acts as a statistical gauge field after a certain critical
    coupling. This critical coupling corresponds to the intersection point between
    the quasiparticle state and the phonon wing, where the angular momentum is transferred
    from the impurity to the bath. This amounts to a novel configuration with emerging
    anyons. The proposed setup paves the way to realizing anyons using electrons interacting
    with superfluid helium or lattice phonons, as well as using atomic impurities
    in ultracold gases.
article_number: '045402'
article_processing_charge: No
arxiv: 1
author:
- first_name: Enderalp
  full_name: Yakaboylu, Enderalp
  id: 38CB71F6-F248-11E8-B48F-1D18A9856A87
  last_name: Yakaboylu
  orcid: 0000-0001-5973-0874
- first_name: Mikhail
  full_name: Lemeshko, Mikhail
  id: 37CB05FA-F248-11E8-B48F-1D18A9856A87
  last_name: Lemeshko
  orcid: 0000-0002-6990-7802
citation:
  ama: Yakaboylu E, Lemeshko M. Anyonic statistics of quantum impurities in two dimensions.
    <i>Physical Review B</i>. 2018;98(4). doi:<a href="https://doi.org/10.1103/PhysRevB.98.045402">10.1103/PhysRevB.98.045402</a>
  apa: Yakaboylu, E., &#38; Lemeshko, M. (2018). Anyonic statistics of quantum impurities
    in two dimensions. <i>Physical Review B</i>. American Physical Society. <a href="https://doi.org/10.1103/PhysRevB.98.045402">https://doi.org/10.1103/PhysRevB.98.045402</a>
  chicago: Yakaboylu, Enderalp, and Mikhail Lemeshko. “Anyonic Statistics of Quantum
    Impurities in Two Dimensions.” <i>Physical Review B</i>. American Physical Society,
    2018. <a href="https://doi.org/10.1103/PhysRevB.98.045402">https://doi.org/10.1103/PhysRevB.98.045402</a>.
  ieee: E. Yakaboylu and M. Lemeshko, “Anyonic statistics of quantum impurities in
    two dimensions,” <i>Physical Review B</i>, vol. 98, no. 4. American Physical Society,
    2018.
  ista: Yakaboylu E, Lemeshko M. 2018. Anyonic statistics of quantum impurities in
    two dimensions. Physical Review B. 98(4), 045402.
  mla: Yakaboylu, Enderalp, and Mikhail Lemeshko. “Anyonic Statistics of Quantum Impurities
    in Two Dimensions.” <i>Physical Review B</i>, vol. 98, no. 4, 045402, American
    Physical Society, 2018, doi:<a href="https://doi.org/10.1103/PhysRevB.98.045402">10.1103/PhysRevB.98.045402</a>.
  short: E. Yakaboylu, M. Lemeshko, Physical Review B 98 (2018).
corr_author: '1'
date_created: 2018-12-11T11:45:08Z
date_published: 2018-07-15T00:00:00Z
date_updated: 2026-08-12T14:24:49Z
day: '15'
department:
- _id: MiLe
doi: 10.1103/PhysRevB.98.045402
ec_funded: 1
external_id:
  arxiv:
  - '1712.00308'
  isi:
  - '000436939100007'
fulldoi: https://doi.org/10.1103/PhysRevB.98.045402
intvolume: '        98'
isi: 1
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1712.00308
month: '07'
oa: 1
oa_version: Submitted Version
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
- _id: 26031614-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P29902
  name: Quantum rotations in the presence of a many-body environment
publication: Physical Review B
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Anyonic statistics of quantum impurities in two dimensions
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 98
year: '2018'
...
---
_id: '5971'
abstract:
- lang: eng
  text: "We consider a Wigner-type ensemble, i.e. large hermitian N×N random matrices
    H=H∗ with centered independent entries and with a general matrix of variances
    Sxy=\U0001D53C∣∣Hxy∣∣2. The norm of H is asymptotically given by the maximum of
    the support of the self-consistent density of states. We establish a bound on
    this maximum in terms of norms of powers of S that substantially improves the
    earlier bound 2∥S∥1/2∞ given in [O. Ajanki, L. Erdős and T. Krüger, Universality
    for general Wigner-type matrices, Prob. Theor. Rel. Fields169 (2017) 667–727].
    The key element of the proof is an effective Markov chain approximation for the
    contributions of the weighted Dyck paths appearing in the iterative solution of
    the corresponding Dyson equation."
article_number: '1950009'
article_processing_charge: No
arxiv: 1
author:
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
- first_name: Peter
  full_name: Mühlbacher, Peter
  last_name: Mühlbacher
citation:
  ama: 'Erdös L, Mühlbacher P. Bounds on the norm of Wigner-type random matrices.
    <i>Random Matrices: Theory and Applications</i>. 2018. doi:<a href="https://doi.org/10.1142/s2010326319500096">10.1142/s2010326319500096</a>'
  apa: 'Erdös, L., &#38; Mühlbacher, P. (2018). Bounds on the norm of Wigner-type
    random matrices. <i>Random Matrices: Theory and Applications</i>. World Scientific
    Publishing. <a href="https://doi.org/10.1142/s2010326319500096">https://doi.org/10.1142/s2010326319500096</a>'
  chicago: 'Erdös, László, and Peter Mühlbacher. “Bounds on the Norm of Wigner-Type
    Random Matrices.” <i>Random Matrices: Theory and Applications</i>. World Scientific
    Publishing, 2018. <a href="https://doi.org/10.1142/s2010326319500096">https://doi.org/10.1142/s2010326319500096</a>.'
  ieee: 'L. Erdös and P. Mühlbacher, “Bounds on the norm of Wigner-type random matrices,”
    <i>Random Matrices: Theory and Applications</i>. World Scientific Publishing,
    2018.'
  ista: 'Erdös L, Mühlbacher P. 2018. Bounds on the norm of Wigner-type random matrices.
    Random Matrices: Theory and Applications., 1950009.'
  mla: 'Erdös, László, and Peter Mühlbacher. “Bounds on the Norm of Wigner-Type Random
    Matrices.” <i>Random Matrices: Theory and Applications</i>, 1950009, World Scientific
    Publishing, 2018, doi:<a href="https://doi.org/10.1142/s2010326319500096">10.1142/s2010326319500096</a>.'
  short: 'L. Erdös, P. Mühlbacher, Random Matrices: Theory and Applications (2018).'
date_created: 2019-02-13T10:40:54Z
date_published: 2018-09-26T00:00:00Z
date_updated: 2026-08-12T14:33:01Z
day: '26'
department:
- _id: LaEr
doi: 10.1142/s2010326319500096
ec_funded: 1
external_id:
  arxiv:
  - '1802.05175'
  isi:
  - '000477677200002'
fulldoi: https://doi.org/10.1142/s2010326319500096
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1802.05175
month: '09'
oa: 1
oa_version: Preprint
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '338804'
  name: Random matrices, universality and disordered quantum systems
publication: 'Random Matrices: Theory and Applications'
publication_identifier:
  eissn:
  - 2010-3271
  issn:
  - 2010-3263
publication_status: published
publisher: World Scientific Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: Bounds on the norm of Wigner-type random matrices
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2018'
...
---
_id: '5978'
abstract:
- lang: eng
  text: 'We consider the MAP-inference problem for graphical models,which is a valued
    constraint satisfaction problem defined onreal numbers with a natural summation
    operation. We proposea family of relaxations (different from the famous Sherali-Adams
    hierarchy), which naturally define lower bounds for itsoptimum. This family always
    contains a tight relaxation andwe give an algorithm able to find it and therefore,
    solve theinitial non-relaxed NP-hard problem.The relaxations we consider decompose
    the original probleminto two non-overlapping parts: an easy LP-tight part and
    adifficult one. For the latter part a combinatorial solver must beused. As we
    show in our experiments, in a number of applica-tions the second, difficult part
    constitutes only a small fractionof the whole problem. This property allows to
    significantlyreduce the computational time of the combinatorial solver andtherefore
    solve problems which were out of reach before.'
article_processing_charge: No
arxiv: 1
author:
- first_name: Stefan
  full_name: Haller, Stefan
  last_name: Haller
- first_name: Paul
  full_name: Swoboda, Paul
  id: 446560C6-F248-11E8-B48F-1D18A9856A87
  last_name: Swoboda
- first_name: Bogdan
  full_name: Savchynskyy, Bogdan
  last_name: Savchynskyy
citation:
  ama: 'Haller S, Swoboda P, Savchynskyy B. Exact MAP-inference by confining combinatorial
    search with LP relaxation. In: <i>Proceedings of the 32st AAAI Conference on Artificial
    Intelligence</i>. AAAI Press; 2018:6581-6588. doi:<a href="https://doi.org/10.1609/aaai.v32i1.12202">10.1609/aaai.v32i1.12202</a>'
  apa: 'Haller, S., Swoboda, P., &#38; Savchynskyy, B. (2018). Exact MAP-inference
    by confining combinatorial search with LP relaxation. In <i>Proceedings of the
    32st AAAI Conference on Artificial Intelligence</i> (pp. 6581–6588). New Orleans,
    LU, United States: AAAI Press. <a href="https://doi.org/10.1609/aaai.v32i1.12202">https://doi.org/10.1609/aaai.v32i1.12202</a>'
  chicago: Haller, Stefan, Paul Swoboda, and Bogdan Savchynskyy. “Exact MAP-Inference
    by Confining Combinatorial Search with LP Relaxation.” In <i>Proceedings of the
    32st AAAI Conference on Artificial Intelligence</i>, 6581–88. AAAI Press, 2018.
    <a href="https://doi.org/10.1609/aaai.v32i1.12202">https://doi.org/10.1609/aaai.v32i1.12202</a>.
  ieee: S. Haller, P. Swoboda, and B. Savchynskyy, “Exact MAP-inference by confining
    combinatorial search with LP relaxation,” in <i>Proceedings of the 32st AAAI Conference
    on Artificial Intelligence</i>, New Orleans, LU, United States, 2018, pp. 6581–6588.
  ista: 'Haller S, Swoboda P, Savchynskyy B. 2018. Exact MAP-inference by confining
    combinatorial search with LP relaxation. Proceedings of the 32st AAAI Conference
    on Artificial Intelligence. AAAI: Conference on Artificial Intelligence, 6581–6588.'
  mla: Haller, Stefan, et al. “Exact MAP-Inference by Confining Combinatorial Search
    with LP Relaxation.” <i>Proceedings of the 32st AAAI Conference on Artificial
    Intelligence</i>, AAAI Press, 2018, pp. 6581–88, doi:<a href="https://doi.org/10.1609/aaai.v32i1.12202">10.1609/aaai.v32i1.12202</a>.
  short: S. Haller, P. Swoboda, B. Savchynskyy, in:, Proceedings of the 32st AAAI
    Conference on Artificial Intelligence, AAAI Press, 2018, pp. 6581–6588.
conference:
  end_date: 2018-02-07
  location: New Orleans, LU, United States
  name: 'AAAI: Conference on Artificial Intelligence'
  start_date: 2018-02-02
date_created: 2019-02-13T13:32:48Z
date_published: 2018-02-01T00:00:00Z
date_updated: 2026-08-19T09:30:58Z
day: '01'
department:
- _id: VlKo
doi: 10.1609/aaai.v32i1.12202
external_id:
  arxiv:
  - '2004.06370'
  isi:
  - '000485488906082'
fulldoi: https://doi.org/10.1609/aaai.v32i1.12202
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2004.06370
month: '02'
oa: 1
oa_version: Preprint
page: 6581-6588
publication: Proceedings of the 32st AAAI Conference on Artificial Intelligence
publication_status: published
publisher: AAAI Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Exact MAP-inference by confining combinatorial search with LP relaxation
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2018'
...
---
_id: '3'
abstract:
- lang: eng
  text: SETD5 gene mutations have been identified as a frequent cause of idiopathic
    intellectual disability. Here we show that Setd5-haploinsufficient mice present
    developmental defects such as abnormal brain-to-body weight ratios and neural
    crest defect-associated phenotypes. Furthermore, Setd5-mutant mice show impairments
    in cognitive tasks, enhanced long-term potentiation, delayed ontogenetic profile
    of ultrasonic vocalization, and behavioral inflexibility. Behavioral issues are
    accompanied by abnormal expression of postsynaptic density proteins previously
    associated with cognition. Our data additionally indicate that Setd5 regulates
    RNA polymerase II dynamics and gene transcription via its interaction with the
    Hdac3 and Paf1 complexes, findings potentially explaining the gene expression
    defects observed in Setd5-haploinsufficient mice. Our results emphasize the decisive
    role of Setd5 in a biological pathway found to be disrupted in humans with intellectual
    disability and autism spectrum disorder.
acknowledged_ssus:
- _id: M-Shop
- _id: PreCl
acknowledgement: This work was supported by the Simons Foundation Autism Research
  Initiative (grant 401299) to G.N. and the DFG (SPP1738 grant NO 1249) to K.-M.N.
article_processing_charge: No
article_type: original
author:
- first_name: Elena
  full_name: Deliu, Elena
  id: 37A40D7E-F248-11E8-B48F-1D18A9856A87
  last_name: Deliu
  orcid: 0000-0002-7370-5293
- first_name: Niccoló
  full_name: Arecco, Niccoló
  last_name: Arecco
- first_name: Jasmin
  full_name: Morandell, Jasmin
  id: 4739D480-F248-11E8-B48F-1D18A9856A87
  last_name: Morandell
- first_name: Christoph
  full_name: Dotter, Christoph
  id: 4C66542E-F248-11E8-B48F-1D18A9856A87
  last_name: Dotter
  orcid: 0000-0002-9033-9096
- first_name: Ximena
  full_name: Contreras, Ximena
  id: 475990FE-F248-11E8-B48F-1D18A9856A87
  last_name: Contreras
- first_name: Charles
  full_name: Girardot, Charles
  last_name: Girardot
- first_name: Eva
  full_name: Käsper, Eva
  last_name: Käsper
- first_name: Alena
  full_name: Kozlova, Alena
  id: C50A9596-02D0-11E9-976E-E38CFE5CBC1D
  last_name: Kozlova
- first_name: Kasumi
  full_name: Kishi, Kasumi
  id: 3065DFC4-F248-11E8-B48F-1D18A9856A87
  last_name: Kishi
  orcid: 0000-0001-6060-4795
- first_name: Ilaria
  full_name: Chiaradia, Ilaria
  id: B6467F20-02D0-11E9-BDA5-E960C241894A
  last_name: Chiaradia
  orcid: 0000-0002-9529-4464
- first_name: Kyung
  full_name: Noh, Kyung
  last_name: Noh
- first_name: Gaia
  full_name: Novarino, Gaia
  id: 3E57A680-F248-11E8-B48F-1D18A9856A87
  last_name: Novarino
  orcid: 0000-0002-7673-7178
citation:
  ama: Deliu E, Arecco N, Morandell J, et al. Haploinsufficiency of the intellectual
    disability gene SETD5 disturbs developmental gene expression and cognition. <i>Nature
    Neuroscience</i>. 2018;21(12):1717-1727. doi:<a href="https://doi.org/10.1038/s41593-018-0266-2">10.1038/s41593-018-0266-2</a>
  apa: Deliu, E., Arecco, N., Morandell, J., Dotter, C., Contreras, X., Girardot,
    C., … Novarino, G. (2018). Haploinsufficiency of the intellectual disability gene
    SETD5 disturbs developmental gene expression and cognition. <i>Nature Neuroscience</i>.
    Nature Publishing Group. <a href="https://doi.org/10.1038/s41593-018-0266-2">https://doi.org/10.1038/s41593-018-0266-2</a>
  chicago: Deliu, Elena, Niccoló Arecco, Jasmin Morandell, Christoph Dotter, Ximena
    Contreras, Charles Girardot, Eva Käsper, et al. “Haploinsufficiency of the Intellectual
    Disability Gene SETD5 Disturbs Developmental Gene Expression and Cognition.” <i>Nature
    Neuroscience</i>. Nature Publishing Group, 2018. <a href="https://doi.org/10.1038/s41593-018-0266-2">https://doi.org/10.1038/s41593-018-0266-2</a>.
  ieee: E. Deliu <i>et al.</i>, “Haploinsufficiency of the intellectual disability
    gene SETD5 disturbs developmental gene expression and cognition,” <i>Nature Neuroscience</i>,
    vol. 21, no. 12. Nature Publishing Group, pp. 1717–1727, 2018.
  ista: Deliu E, Arecco N, Morandell J, Dotter C, Contreras X, Girardot C, Käsper
    E, Kozlova A, Kishi K, Chiaradia I, Noh K, Novarino G. 2018. Haploinsufficiency
    of the intellectual disability gene SETD5 disturbs developmental gene expression
    and cognition. Nature Neuroscience. 21(12), 1717–1727.
  mla: Deliu, Elena, et al. “Haploinsufficiency of the Intellectual Disability Gene
    SETD5 Disturbs Developmental Gene Expression and Cognition.” <i>Nature Neuroscience</i>,
    vol. 21, no. 12, Nature Publishing Group, 2018, pp. 1717–27, doi:<a href="https://doi.org/10.1038/s41593-018-0266-2">10.1038/s41593-018-0266-2</a>.
  short: E. Deliu, N. Arecco, J. Morandell, C. Dotter, X. Contreras, C. Girardot,
    E. Käsper, A. Kozlova, K. Kishi, I. Chiaradia, K. Noh, G. Novarino, Nature Neuroscience
    21 (2018) 1717–1727.
corr_author: '1'
date_created: 2018-12-11T11:44:05Z
date_published: 2018-11-19T00:00:00Z
date_updated: 2026-10-05T22:30:08Z
day: '19'
ddc:
- '570'
department:
- _id: GaNo
- _id: EdHa
doi: 10.1038/s41593-018-0266-2
external_id:
  isi:
  - '000451324700010'
file:
- access_level: open_access
  checksum: 60abd0f05b7cdc08a6b0ec460884084f
  content_type: application/pdf
  creator: dernst
  date_created: 2019-04-09T07:41:57Z
  date_updated: 2020-07-14T12:45:58Z
  file_id: '6255'
  file_name: 2017_NatureNeuroscience_Deliu.pdf
  file_size: 8167169
  relation: main_file
file_date_updated: 2020-07-14T12:45:58Z
fulldoi: https://doi.org/10.1038/s41593-018-0266-2
has_accepted_license: '1'
intvolume: '        21'
isi: 1
issue: '12'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Submitted Version
page: 1717 - 1727
project:
- _id: 254BA948-B435-11E9-9278-68D0E5697425
  grant_number: '401299'
  name: Probing development and reversibility of autism spectrum disorders
publication: Nature Neuroscience
publication_status: published
publisher: Nature Publishing Group
publist_id: '8054'
pubrep_id: '1071'
quality_controlled: '1'
related_material:
  link:
  - description: News on IST Homepage
    relation: press_release
    url: https://ist.ac.at/en/news/mutation-that-causes-autism-and-intellectual-disability-makes-brain-less-flexible/
  record:
  - id: '6074'
    relation: popular_science
    status: public
  - id: '12364'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Haploinsufficiency of the intellectual disability gene SETD5 disturbs developmental
  gene expression and cognition
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 21
year: '2018'
...
---
OA_place: publisher
_id: '26'
abstract:
- lang: eng
  text: Expression of genes is a fundamental molecular phenotype that is subject to
    evolution by different types of mutations. Both the rate and the effect of mutations
    may depend on the DNA sequence context of a particular gene or a particular promoter
    sequence. In this thesis I investigate the nature of this dependence using simple
    genetic systems in Escherichia coli. With these systems I explore the evolution
    of constitutive gene expression from random starting sequences at different loci
    on the chromosome and at different locations in sequence space. First, I dissect
    chromosomal neighborhood effects that underlie locus-dependent differences in
    the potential of a gene under selection to become more highly expressed. Next,
    I find that the effects of point mutations in promoter sequences are dependent
    on sequence context, and that an existing energy matrix model performs poorly
    in predicting relative expression of unrelated sequences. Finally, I show that
    a substantial fraction of random sequences contain functional promoters and I
    present an extended thermodynamic model that predicts promoter strength in full
    sequence space. Taken together, these results provide new insights and guides
    on how to integrate information on sequence context to improve our qualitative
    and quantitative understanding of bacterial gene expression, with implications
    for rapid evolution of drug resistance, de novo evolution of genes, and horizontal
    gene transfer.
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Magdalena
  full_name: Steinrück, Magdalena
  id: 2C023F40-F248-11E8-B48F-1D18A9856A87
  last_name: Steinrück
  orcid: 0000-0003-1229-9719
citation:
  ama: Steinrück M. The influence of sequence context on the evolution of bacterial
    gene expression. 2018. doi:<a href="https://doi.org/10.15479/AT:ISTA:th1059">10.15479/AT:ISTA:th1059</a>
  apa: Steinrück, M. (2018). <i>The influence of sequence context on the evolution
    of bacterial gene expression</i>. Institute of Science and Technology Austria.
    <a href="https://doi.org/10.15479/AT:ISTA:th1059">https://doi.org/10.15479/AT:ISTA:th1059</a>
  chicago: Steinrück, Magdalena. “The Influence of Sequence Context on the Evolution
    of Bacterial Gene Expression.” Institute of Science and Technology Austria, 2018.
    <a href="https://doi.org/10.15479/AT:ISTA:th1059">https://doi.org/10.15479/AT:ISTA:th1059</a>.
  ieee: M. Steinrück, “The influence of sequence context on the evolution of bacterial
    gene expression,” Institute of Science and Technology Austria, 2018.
  ista: Steinrück M. 2018. The influence of sequence context on the evolution of bacterial
    gene expression. Institute of Science and Technology Austria.
  mla: Steinrück, Magdalena. <i>The Influence of Sequence Context on the Evolution
    of Bacterial Gene Expression</i>. Institute of Science and Technology Austria,
    2018, doi:<a href="https://doi.org/10.15479/AT:ISTA:th1059">10.15479/AT:ISTA:th1059</a>.
  short: M. Steinrück, The Influence of Sequence Context on the Evolution of Bacterial
    Gene Expression, Institute of Science and Technology Austria, 2018.
corr_author: '1'
date_created: 2018-12-11T11:44:14Z
date_published: 2018-10-30T00:00:00Z
date_updated: 2026-04-08T14:15:35Z
day: '30'
ddc:
- '576'
- '579'
degree_awarded: PhD
department:
- _id: CaGu
doi: 10.15479/AT:ISTA:th1059
file:
- access_level: closed
  checksum: 413cbce1cd1debeae3abe2a25dbc70d1
  content_type: application/vnd.openxmlformats-officedocument.wordprocessingml.document
  creator: dernst
  date_created: 2019-02-08T10:51:22Z
  date_updated: 2020-07-14T12:45:43Z
  embargo_to: open_access
  file_id: '5941'
  file_name: Thesis_Steinrueck_final.docx
  file_size: 9190845
  relation: source_file
- access_level: open_access
  checksum: 3def8b7854c8b42d643597ce0215efac
  content_type: application/pdf
  creator: dernst
  date_created: 2019-02-08T10:51:22Z
  date_updated: 2021-02-11T11:17:14Z
  embargo: 2019-11-02
  file_id: '5942'
  file_name: Thesis_Steinrueck_final.pdf
  file_size: 7521973
  relation: main_file
file_date_updated: 2021-02-11T11:17:14Z
fulldoi: https://doi.org/10.15479/AT:ISTA:th1059
has_accepted_license: '1'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
page: '109'
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '8029'
pubrep_id: '1059'
related_material:
  record:
  - id: '704'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Calin C
  full_name: Guet, Calin C
  id: 47F8433E-F248-11E8-B48F-1D18A9856A87
  last_name: Guet
  orcid: 0000-0001-6220-2052
title: The influence of sequence context on the evolution of bacterial gene expression
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2018'
...
---
_id: '28'
abstract:
- lang: eng
  text: 'This scientific commentary refers to ‘NEGR1 and FGFR2 cooperatively regulate
    cortical development and core behaviours related to autism disorders in mice’
    by Szczurkowska et al. '
article_processing_charge: No
author:
- first_name: Ximena
  full_name: Contreras, Ximena
  id: 475990FE-F248-11E8-B48F-1D18A9856A87
  last_name: Contreras
- first_name: Simon
  full_name: Hippenmeyer, Simon
  id: 37B36620-F248-11E8-B48F-1D18A9856A87
  last_name: Hippenmeyer
  orcid: 0000-0003-2279-1061
citation:
  ama: Contreras X, Hippenmeyer S. Incorrect trafficking route leads to autism. <i>Brain
    a journal of neurology</i>. 2018;141(9):2542-2544. doi:<a href="https://doi.org/10.1093/brain/awy218">10.1093/brain/awy218</a>
  apa: Contreras, X., &#38; Hippenmeyer, S. (2018). Incorrect trafficking route leads
    to autism. <i>Brain a Journal of Neurology</i>. Oxford University Press. <a href="https://doi.org/10.1093/brain/awy218">https://doi.org/10.1093/brain/awy218</a>
  chicago: Contreras, Ximena, and Simon Hippenmeyer. “Incorrect Trafficking Route
    Leads to Autism.” <i>Brain a Journal of Neurology</i>. Oxford University Press,
    2018. <a href="https://doi.org/10.1093/brain/awy218">https://doi.org/10.1093/brain/awy218</a>.
  ieee: X. Contreras and S. Hippenmeyer, “Incorrect trafficking route leads to autism,”
    <i>Brain a journal of neurology</i>, vol. 141, no. 9. Oxford University Press,
    pp. 2542–2544, 2018.
  ista: Contreras X, Hippenmeyer S. 2018. Incorrect trafficking route leads to autism.
    Brain a journal of neurology. 141(9), 2542–2544.
  mla: Contreras, Ximena, and Simon Hippenmeyer. “Incorrect Trafficking Route Leads
    to Autism.” <i>Brain a Journal of Neurology</i>, vol. 141, no. 9, Oxford University
    Press, 2018, pp. 2542–44, doi:<a href="https://doi.org/10.1093/brain/awy218">10.1093/brain/awy218</a>.
  short: X. Contreras, S. Hippenmeyer, Brain a Journal of Neurology 141 (2018) 2542–2544.
date_created: 2018-12-11T11:44:14Z
date_published: 2018-09-01T00:00:00Z
date_updated: 2026-10-05T22:30:22Z
day: '01'
department:
- _id: SiHi
doi: 10.1093/brain/awy218
external_id:
  isi:
  - '000446548100012'
fulldoi: https://doi.org/10.1093/brain/awy218
intvolume: '       141'
isi: 1
issue: '9'
language:
- iso: eng
month: '09'
oa_version: None
page: 2542 - 2544
publication: Brain a journal of neurology
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
related_material:
  record:
  - id: '7902'
    relation: part_of_dissertation
    status: public
scopus_import: '1'
status: public
title: Incorrect trafficking route leads to autism
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 141
year: '2018'
...
---
_id: '15'
abstract:
- lang: eng
  text: Although much is known about the physiological framework of T cell motility,
    and numerous rate-limiting molecules have been identified through loss-of-function
    approaches, an integrated functional concept of T cell motility is lacking. Here,
    we used in vivo precision morphometry together with analysis of cytoskeletal dynamics
    in vitro to deconstruct the basic mechanisms of T cell migration within lymphatic
    organs. We show that the contributions of the integrin LFA-1 and the chemokine
    receptor CCR7 are complementary rather than positioned in a linear pathway, as
    they are during leukocyte extravasation from the blood vasculature. Our data demonstrate
    that CCR7 controls cortical actin flows, whereas integrins mediate substrate friction
    that is sufficient to drive locomotion in the absence of considerable surface
    adhesions and plasma membrane flux.
acknowledged_ssus:
- _id: SSU
acknowledgement: This work was funded by grants from the European Research Council
  (ERC StG 281556 and CoG 724373) and the Austrian Science Foundation (FWF) to M.S.
  and by Swiss National Foundation (SNF) project grants 31003A_135649, 31003A_153457
  and CR23I3_156234 to J.V.S. F.G. received funding from the European Union’s Horizon
  2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement
  no. 747687, and J.R. was funded by an EMBO long-term fellowship (ALTF 1396-2014).
article_processing_charge: No
author:
- first_name: Miroslav
  full_name: Hons, Miroslav
  id: 4167FE56-F248-11E8-B48F-1D18A9856A87
  last_name: Hons
  orcid: 0000-0002-6625-3348
- first_name: Aglaja
  full_name: Kopf, Aglaja
  id: 31DAC7B6-F248-11E8-B48F-1D18A9856A87
  last_name: Kopf
  orcid: 0000-0002-2187-6656
- first_name: Robert
  full_name: Hauschild, Robert
  id: 4E01D6B4-F248-11E8-B48F-1D18A9856A87
  last_name: Hauschild
  orcid: 0000-0001-9843-3522
- first_name: Alexander F
  full_name: Leithner, Alexander F
  id: 3B1B77E4-F248-11E8-B48F-1D18A9856A87
  last_name: Leithner
  orcid: 0000-0002-1073-744X
- first_name: Florian R
  full_name: Gärtner, Florian R
  id: 397A88EE-F248-11E8-B48F-1D18A9856A87
  last_name: Gärtner
  orcid: 0000-0001-6120-3723
- first_name: Jun
  full_name: Abe, Jun
  last_name: Abe
- first_name: Jörg
  full_name: Renkawitz, Jörg
  id: 3F0587C8-F248-11E8-B48F-1D18A9856A87
  last_name: Renkawitz
  orcid: 0000-0003-2856-3369
- first_name: Jens
  full_name: Stein, Jens
  last_name: Stein
- first_name: Michael K
  full_name: Sixt, Michael K
  id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
  last_name: Sixt
  orcid: 0000-0002-6620-9179
citation:
  ama: Hons M, Kopf A, Hauschild R, et al. Chemokines and integrins independently
    tune actin flow and substrate friction during intranodal migration of T cells.
    <i>Nature Immunology</i>. 2018;19(6):606-616. doi:<a href="https://doi.org/10.1038/s41590-018-0109-z">10.1038/s41590-018-0109-z</a>
  apa: Hons, M., Kopf, A., Hauschild, R., Leithner, A. F., Gärtner, F. R., Abe, J.,
    … Sixt, M. K. (2018). Chemokines and integrins independently tune actin flow and
    substrate friction during intranodal migration of T cells. <i>Nature Immunology</i>.
    Nature Publishing Group. <a href="https://doi.org/10.1038/s41590-018-0109-z">https://doi.org/10.1038/s41590-018-0109-z</a>
  chicago: Hons, Miroslav, Aglaja Kopf, Robert Hauschild, Alexander F Leithner, Florian
    R Gärtner, Jun Abe, Jörg Renkawitz, Jens Stein, and Michael K Sixt. “Chemokines
    and Integrins Independently Tune Actin Flow and Substrate Friction during Intranodal
    Migration of T Cells.” <i>Nature Immunology</i>. Nature Publishing Group, 2018.
    <a href="https://doi.org/10.1038/s41590-018-0109-z">https://doi.org/10.1038/s41590-018-0109-z</a>.
  ieee: M. Hons <i>et al.</i>, “Chemokines and integrins independently tune actin
    flow and substrate friction during intranodal migration of T cells,” <i>Nature
    Immunology</i>, vol. 19, no. 6. Nature Publishing Group, pp. 606–616, 2018.
  ista: Hons M, Kopf A, Hauschild R, Leithner AF, Gärtner FR, Abe J, Renkawitz J,
    Stein J, Sixt MK. 2018. Chemokines and integrins independently tune actin flow
    and substrate friction during intranodal migration of T cells. Nature Immunology.
    19(6), 606–616.
  mla: Hons, Miroslav, et al. “Chemokines and Integrins Independently Tune Actin Flow
    and Substrate Friction during Intranodal Migration of T Cells.” <i>Nature Immunology</i>,
    vol. 19, no. 6, Nature Publishing Group, 2018, pp. 606–16, doi:<a href="https://doi.org/10.1038/s41590-018-0109-z">10.1038/s41590-018-0109-z</a>.
  short: M. Hons, A. Kopf, R. Hauschild, A.F. Leithner, F.R. Gärtner, J. Abe, J. Renkawitz,
    J. Stein, M.K. Sixt, Nature Immunology 19 (2018) 606–616.
date_created: 2018-12-11T11:44:10Z
date_published: 2018-05-18T00:00:00Z
date_updated: 2026-10-05T22:30:26Z
day: '18'
ddc:
- '570'
department:
- _id: MiSi
- _id: Bio
doi: 10.1038/s41590-018-0109-z
ec_funded: 1
external_id:
  isi:
  - '000433041500026'
  pmid:
  - '29777221'
fulldoi: https://doi.org/10.1038/s41590-018-0109-z
intvolume: '        19'
isi: 1
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pubmed/29777221
month: '05'
oa: 1
oa_version: Published Version
page: 606 - 616
pmid: 1
project:
- _id: 25FE9508-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '724373'
  name: Cellular Navigation Along Spatial Gradients
- _id: 260AA4E2-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '747687'
  name: Mechanical Adaptation of Lamellipodial Actin Networks in Migrating Cells
- _id: 25A48D24-B435-11E9-9278-68D0E5697425
  grant_number: ALTF 1396-2014
  name: Molecular and system level view of immune cell migration
- _id: 25A603A2-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '281556'
  name: Cytoskeletal force generation and force transduction of migrating leukocytes
publication: Nature Immunology
publication_status: published
publisher: Nature Publishing Group
publist_id: '8040'
quality_controlled: '1'
related_material:
  record:
  - id: '6891'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Chemokines and integrins independently tune actin flow and substrate friction
  during intranodal migration of T cells
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 19
year: '2018'
...
---
_id: '422'
abstract:
- lang: eng
  text: We show that a rather simple, steady modification of the streamwise velocity
    profile in a pipe can lead to a complete collapse of turbulence and the flow fully
    relaminarizes. Two different devices, a stationary obstacle (inset) and a device
    which injects fluid through an annular gap close to the wall, are used to control
    the flow. Both devices modify the streamwise velocity profile such that the flow
    in the center of the pipe is decelerated and the flow in the near wall region
    is accelerated. We present measurements with stereoscopic particle image velocimetry
    to investigate and capture the development of the relaminarizing flow downstream
    these devices and the specific circumstances responsible for relaminarization.
    We find total relaminarization up to Reynolds numbers of 6000, where the skin
    friction in the far downstream distance is reduced by a factor of 3.4 due to relaminarization.
    In a smooth straight pipe the flow remains completely laminar downstream of the
    control. Furthermore, we show that transient (temporary) relaminarization in a
    spatially confined region right downstream the devices occurs also at much higher
    Reynolds numbers, accompanied by a significant local skin friction drag reduction.
    The underlying physical mechanism of relaminarization is attributed to a weakening
    of the near-wall turbulence production cycle.
article_processing_charge: Yes (via OA deal)
author:
- first_name: Jakob
  full_name: Kühnen, Jakob
  id: 3A47AE32-F248-11E8-B48F-1D18A9856A87
  last_name: Kühnen
  orcid: 0000-0003-4312-0179
- first_name: Davide
  full_name: Scarselli, Davide
  id: 40315C30-F248-11E8-B48F-1D18A9856A87
  last_name: Scarselli
  orcid: 0000-0001-5227-4271
- first_name: Markus
  full_name: Schaner, Markus
  id: 316CE034-F248-11E8-B48F-1D18A9856A87
  last_name: Schaner
- first_name: Björn
  full_name: Hof, Björn
  id: 3A374330-F248-11E8-B48F-1D18A9856A87
  last_name: Hof
  orcid: 0000-0003-2057-2754
citation:
  ama: Kühnen J, Scarselli D, Schaner M, Hof B. Relaminarization by steady modification
    of the streamwise velocity profile in a pipe. <i>Flow Turbulence and Combustion</i>.
    2018;100(4):919-942. doi:<a href="https://doi.org/10.1007/s10494-018-9896-4">10.1007/s10494-018-9896-4</a>
  apa: Kühnen, J., Scarselli, D., Schaner, M., &#38; Hof, B. (2018). Relaminarization
    by steady modification of the streamwise velocity profile in a pipe. <i>Flow Turbulence
    and Combustion</i>. Springer. <a href="https://doi.org/10.1007/s10494-018-9896-4">https://doi.org/10.1007/s10494-018-9896-4</a>
  chicago: Kühnen, Jakob, Davide Scarselli, Markus Schaner, and Björn Hof. “Relaminarization
    by Steady Modification of the Streamwise Velocity Profile in a Pipe.” <i>Flow
    Turbulence and Combustion</i>. Springer, 2018. <a href="https://doi.org/10.1007/s10494-018-9896-4">https://doi.org/10.1007/s10494-018-9896-4</a>.
  ieee: J. Kühnen, D. Scarselli, M. Schaner, and B. Hof, “Relaminarization by steady
    modification of the streamwise velocity profile in a pipe,” <i>Flow Turbulence
    and Combustion</i>, vol. 100, no. 4. Springer, pp. 919–942, 2018.
  ista: Kühnen J, Scarselli D, Schaner M, Hof B. 2018. Relaminarization by steady
    modification of the streamwise velocity profile in a pipe. Flow Turbulence and
    Combustion. 100(4), 919–942.
  mla: Kühnen, Jakob, et al. “Relaminarization by Steady Modification of the Streamwise
    Velocity Profile in a Pipe.” <i>Flow Turbulence and Combustion</i>, vol. 100,
    no. 4, Springer, 2018, pp. 919–42, doi:<a href="https://doi.org/10.1007/s10494-018-9896-4">10.1007/s10494-018-9896-4</a>.
  short: J. Kühnen, D. Scarselli, M. Schaner, B. Hof, Flow Turbulence and Combustion
    100 (2018) 919–942.
corr_author: '1'
date_created: 2018-12-11T11:46:23Z
date_published: 2018-01-01T00:00:00Z
date_updated: 2026-10-05T22:30:30Z
day: '01'
ddc:
- '530'
department:
- _id: BjHo
doi: 10.1007/s10494-018-9896-4
ec_funded: 1
external_id:
  isi:
  - '000433113900004'
file:
- access_level: open_access
  checksum: d7c0bade150faabca150b0a9986e60ca
  content_type: application/pdf
  creator: dernst
  date_created: 2018-12-17T15:52:37Z
  date_updated: 2020-07-14T12:46:25Z
  file_id: '5717'
  file_name: 2018_FlowTurbulenceCombust_Kuehnen.pdf
  file_size: 2210020
  relation: main_file
file_date_updated: 2020-07-14T12:46:25Z
fulldoi: https://doi.org/10.1007/s10494-018-9896-4
has_accepted_license: '1'
intvolume: '       100'
isi: 1
issue: '4'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 919 - 942
project:
- _id: 25152F3A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '306589'
  name: Decoding the complexity of turbulence at its origin
publication: Flow Turbulence and Combustion
publication_status: published
publisher: Springer
publist_id: '7401'
quality_controlled: '1'
related_material:
  record:
  - id: '7258'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Relaminarization by steady modification of the streamwise velocity profile
  in a pipe
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 100
year: '2018'
...
---
_id: '461'
abstract:
- lang: eng
  text: Turbulence is the major cause of friction losses in transport processes and
    it is responsible for a drastic drag increase in flows over bounding surfaces.
    While much effort is invested into developing ways to control and reduce turbulence
    intensities, so far no methods exist to altogether eliminate turbulence if velocities
    are sufficiently large. We demonstrate for pipe flow that appropriate distortions
    to the velocity profile lead to a complete collapse of turbulence and subsequently
    friction losses are reduced by as much as 90%. Counterintuitively, the return
    to laminar motion is accomplished by initially increasing turbulence intensities
    or by transiently amplifying wall shear. Since neither the Reynolds number nor
    the shear stresses decrease (the latter often increase), these measures are not
    indicative of turbulence collapse. Instead, an amplification mechanism                      measuring
    the interaction between eddies and the mean shear is found to set a threshold
    below which turbulence is suppressed beyond recovery.
acknowledgement: We acknowledge the European Research Council under the European Union’s
  Seventh Framework Programme (FP/2007-2013)/ERC Grant Agreement 306589, the European
  Research Council (ERC) under the European Union’s Horizon 2020 research and innovation
  programme (grant agreement no. 737549) and the Deutsche Forschungsgemeinschaft (Project
  No. FOR 1182) for financial support. We thank our technician P. Maier for providing
  highly valuable ideas and greatly supporting us in all technical aspects. We thank
  M. Schaner for technical drawings, construction and design. We thank M. Schwegel
  for a Matlab code to post-process experimental data.
article_processing_charge: No
arxiv: 1
author:
- first_name: Jakob
  full_name: Kühnen, Jakob
  id: 3A47AE32-F248-11E8-B48F-1D18A9856A87
  last_name: Kühnen
  orcid: 0000-0003-4312-0179
- first_name: Baofang
  full_name: Song, Baofang
  last_name: Song
- first_name: Davide
  full_name: Scarselli, Davide
  id: 40315C30-F248-11E8-B48F-1D18A9856A87
  last_name: Scarselli
  orcid: 0000-0001-5227-4271
- first_name: Nazmi B
  full_name: Budanur, Nazmi B
  id: 3EA1010E-F248-11E8-B48F-1D18A9856A87
  last_name: Budanur
  orcid: 0000-0003-0423-5010
- first_name: Michael
  full_name: Riedl, Michael
  id: 3BE60946-F248-11E8-B48F-1D18A9856A87
  last_name: Riedl
  orcid: 0000-0003-4844-6311
- first_name: Ashley
  full_name: Willis, Ashley
  last_name: Willis
- first_name: Marc
  full_name: Avila, Marc
  last_name: Avila
- first_name: Björn
  full_name: Hof, Björn
  id: 3A374330-F248-11E8-B48F-1D18A9856A87
  last_name: Hof
  orcid: 0000-0003-2057-2754
citation:
  ama: Kühnen J, Song B, Scarselli D, et al. Destabilizing turbulence in pipe flow.
    <i>Nature Physics</i>. 2018;14:386-390. doi:<a href="https://doi.org/10.1038/s41567-017-0018-3">10.1038/s41567-017-0018-3</a>
  apa: Kühnen, J., Song, B., Scarselli, D., Budanur, N. B., Riedl, M., Willis, A.,
    … Hof, B. (2018). Destabilizing turbulence in pipe flow. <i>Nature Physics</i>.
    Nature Publishing Group. <a href="https://doi.org/10.1038/s41567-017-0018-3">https://doi.org/10.1038/s41567-017-0018-3</a>
  chicago: Kühnen, Jakob, Baofang Song, Davide Scarselli, Nazmi B Budanur, Michael
    Riedl, Ashley Willis, Marc Avila, and Björn Hof. “Destabilizing Turbulence in
    Pipe Flow.” <i>Nature Physics</i>. Nature Publishing Group, 2018. <a href="https://doi.org/10.1038/s41567-017-0018-3">https://doi.org/10.1038/s41567-017-0018-3</a>.
  ieee: J. Kühnen <i>et al.</i>, “Destabilizing turbulence in pipe flow,” <i>Nature
    Physics</i>, vol. 14. Nature Publishing Group, pp. 386–390, 2018.
  ista: Kühnen J, Song B, Scarselli D, Budanur NB, Riedl M, Willis A, Avila M, Hof
    B. 2018. Destabilizing turbulence in pipe flow. Nature Physics. 14, 386–390.
  mla: Kühnen, Jakob, et al. “Destabilizing Turbulence in Pipe Flow.” <i>Nature Physics</i>,
    vol. 14, Nature Publishing Group, 2018, pp. 386–90, doi:<a href="https://doi.org/10.1038/s41567-017-0018-3">10.1038/s41567-017-0018-3</a>.
  short: J. Kühnen, B. Song, D. Scarselli, N.B. Budanur, M. Riedl, A. Willis, M. Avila,
    B. Hof, Nature Physics 14 (2018) 386–390.
corr_author: '1'
date_created: 2018-12-11T11:46:36Z
date_published: 2018-01-08T00:00:00Z
date_updated: 2026-10-05T22:30:31Z
day: '08'
department:
- _id: BjHo
doi: 10.1038/s41567-017-0018-3
ec_funded: 1
external_id:
  arxiv:
  - '1711.06543'
  isi:
  - '000429434100020'
fulldoi: https://doi.org/10.1038/s41567-017-0018-3
intvolume: '        14'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1711.06543
month: '01'
oa: 1
oa_version: Preprint
page: 386-390
project:
- _id: 25152F3A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '306589'
  name: Decoding the complexity of turbulence at its origin
- _id: 25104D44-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '737549'
  name: Eliminating turbulence in oil pipelines
publication: Nature Physics
publication_status: published
publisher: Nature Publishing Group
publist_id: '7360'
quality_controlled: '1'
related_material:
  record:
  - id: '12726'
    relation: dissertation_contains
    status: public
  - id: '14530'
    relation: dissertation_contains
    status: public
  - id: '7258'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Destabilizing turbulence in pipe flow
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 14
year: '2018'
...
---
_id: '412'
abstract:
- lang: eng
  text: Clathrin-mediated endocytosis (CME) is a cellular trafficking process in which
    cargoes and lipids are internalized from the plasma membrane into vesicles coated
    with clathrin and adaptor proteins. CME is essential for many developmental and
    physiological processes in plants, but its underlying mechanism is not well characterised
    compared to that in yeast and animal systems. Here, we searched for new factors
    involved in CME in Arabidopsis thaliana by performing Tandem Affinity Purification
    of proteins that interact with clathrin light chain, a principal component of
    the clathrin coat. Among the confirmed interactors, we found two putative homologues
    of the clathrin-coat uncoating factor auxilin previously described in non-plant
    systems. Overexpression of AUXILIN-LIKE1 and AUXILIN-LIKE2 in A. thaliana caused
    an arrest of seedling growth and development. This was concomitant with inhibited
    endocytosis due to blocking of clathrin recruitment after the initial step of
    adaptor protein binding to the plasma membrane. By contrast, auxilin-like(1/2)
    loss-of-function lines did not present endocytosis-related developmental or cellular
    phenotypes under normal growth conditions. This work contributes to the on-going
    characterization of the endocytotic machinery in plants and provides a robust
    tool for conditionally and specifically interfering with CME in A. thaliana.
acknowledgement: We thank James Matthew Watson, Monika Borowska, and Peggy Stolt-Bergner
  at ProTech Facility of the Vienna Biocenter Core Facilities for the CRISPR/CAS9
  construct; Anna Müller for assistance with molecular cloning; Sebastian Bednarek,
  Liwen Jiang, and Daniël Van Damme for sharing published material; Matyáš Fendrych,
  Daniël Van Damme, and Lindy Abas for valuable discussions; and Martine De Cock for
  help with correcting the manuscript. This work was supported by the European Research
  Council under the European Union Seventh Framework Programme (FP7/2007-2013)/ERC
  Grant 282300 and by the Ministry of Education of the Czech Republic/MŠMT project
  NPUI-LO1417.
article_processing_charge: No
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- first_name: Maciek
  full_name: Adamowski, Maciek
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  last_name: Adamowski
  orcid: 0000-0001-6463-5257
- first_name: Madhumitha
  full_name: Narasimhan, Madhumitha
  id: 44BF24D0-F248-11E8-B48F-1D18A9856A87
  last_name: Narasimhan
  orcid: 0000-0002-8600-0671
- first_name: Urszula
  full_name: Kania, Urszula
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  last_name: Kania
- first_name: Matous
  full_name: Glanc, Matous
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  last_name: Glanc
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- first_name: Geert
  full_name: De Jaeger, Geert
  last_name: De Jaeger
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citation:
  ama: Adamowski M, Narasimhan M, Kania U, Glanc M, De Jaeger G, Friml J. A functional
    study of AUXILIN LIKE1 and 2 two putative clathrin uncoating factors in Arabidopsis.
    <i>The Plant Cell</i>. 2018;30(3):700-716. doi:<a href="https://doi.org/10.1105/tpc.17.00785">10.1105/tpc.17.00785</a>
  apa: Adamowski, M., Narasimhan, M., Kania, U., Glanc, M., De Jaeger, G., &#38; Friml,
    J. (2018). A functional study of AUXILIN LIKE1 and 2 two putative clathrin uncoating
    factors in Arabidopsis. <i>The Plant Cell</i>. American Society of Plant Biologists.
    <a href="https://doi.org/10.1105/tpc.17.00785">https://doi.org/10.1105/tpc.17.00785</a>
  chicago: Adamowski, Maciek, Madhumitha Narasimhan, Urszula Kania, Matous Glanc,
    Geert De Jaeger, and Jiří Friml. “A Functional Study of AUXILIN LIKE1 and 2 Two
    Putative Clathrin Uncoating Factors in Arabidopsis.” <i>The Plant Cell</i>. American
    Society of Plant Biologists, 2018. <a href="https://doi.org/10.1105/tpc.17.00785">https://doi.org/10.1105/tpc.17.00785</a>.
  ieee: M. Adamowski, M. Narasimhan, U. Kania, M. Glanc, G. De Jaeger, and J. Friml,
    “A functional study of AUXILIN LIKE1 and 2 two putative clathrin uncoating factors
    in Arabidopsis,” <i>The Plant Cell</i>, vol. 30, no. 3. American Society of Plant
    Biologists, pp. 700–716, 2018.
  ista: Adamowski M, Narasimhan M, Kania U, Glanc M, De Jaeger G, Friml J. 2018. A
    functional study of AUXILIN LIKE1 and 2 two putative clathrin uncoating factors
    in Arabidopsis. The Plant Cell. 30(3), 700–716.
  mla: Adamowski, Maciek, et al. “A Functional Study of AUXILIN LIKE1 and 2 Two Putative
    Clathrin Uncoating Factors in Arabidopsis.” <i>The Plant Cell</i>, vol. 30, no.
    3, American Society of Plant Biologists, 2018, pp. 700–16, doi:<a href="https://doi.org/10.1105/tpc.17.00785">10.1105/tpc.17.00785</a>.
  short: M. Adamowski, M. Narasimhan, U. Kania, M. Glanc, G. De Jaeger, J. Friml,
    The Plant Cell 30 (2018) 700–716.
corr_author: '1'
date_created: 2018-12-11T11:46:20Z
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publication: The Plant Cell
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status: public
title: A functional study of AUXILIN LIKE1 and 2 two putative clathrin uncoating factors
  in Arabidopsis
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abstract:
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  text: 'The hippocampus is a key brain region for spatial memory and navigation and
    is needed at all stages of memory, including encoding, consolidation, and recall.
    Hippocampal place cells selectively discharge at specific locations of the environment
    to form a cognitive map of the space. During the rest period and sleep following
    spatial navigation and/or learning, the waking activity of the place cells is
    reactivated within high synchrony events. This reactivation is thought to be important
    for memory consolidation and stabilization of the spatial representations. The
    aim of my thesis was to directly test whether the reactivation content encoded
    in firing patterns of place cells is important for consolidation of spatial memories.
    In particular, I aimed to test whether, in cases when multiple spatial memory
    traces are acquired during learning, the specific disruption of the reactivation
    of a subset of these memories leads to the selective disruption of the corresponding
    memory traces or through memory interference the other learned memories are disrupted
    as well. In this thesis, using a modified cheeseboard paradigm and a closed-loop
    recording setup with feedback optogenetic stimulation, I examined how the disruption
    of the reactivation of specific spiking patterns affects consolidation of the
    corresponding memory traces. To obtain multiple distinctive memories, animals
    had to perform a spatial task in two distinct cheeseboard environments and the
    reactivation of spiking patterns associated with one of the environments (target)
    was disrupted after learning during four hours rest period using a real-time decoding
    method. This real-time decoding method was capable of selectively affecting the
    firing rates and cofiring correlations of the target environment-encoding cells.
    The selective disruption led to behavioural impairment in the memory tests after
    the rest periods in the target environment but not in the other undisrupted control
    environment. In addition, the map of the target environment was less stable in
    the impaired memory tests compared to the learning session before than the map
    of the control environment. However, when the animal relearned the task, the same
    map recurred in the target environment that was present during learning before
    the disruption. Altogether my work demonstrated that the reactivation content
    is important: assembly-related disruption of reactivation can lead to a selective
    memory impairment and deficiency in map stability. These findings indeed suggest
    that reactivated assembly patterns reflect processes associated with the consolidation
    of memory traces. '
alternative_title:
- ISTA Thesis
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author:
- first_name: Igor
  full_name: Gridchyn, Igor
  id: 4B60654C-F248-11E8-B48F-1D18A9856A87
  last_name: Gridchyn
  orcid: 0000-0002-1807-1929
citation:
  ama: Gridchyn I. Reactivation content is important for consolidation of spatial
    memory. 2018. doi:<a href="https://doi.org/10.15479/AT:ISTA:th_1042">10.15479/AT:ISTA:th_1042</a>
  apa: Gridchyn, I. (2018). <i>Reactivation content is important for consolidation
    of spatial memory</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:th_1042">https://doi.org/10.15479/AT:ISTA:th_1042</a>
  chicago: Gridchyn, Igor. “Reactivation Content Is Important for Consolidation of
    Spatial Memory.” Institute of Science and Technology Austria, 2018. <a href="https://doi.org/10.15479/AT:ISTA:th_1042">https://doi.org/10.15479/AT:ISTA:th_1042</a>.
  ieee: I. Gridchyn, “Reactivation content is important for consolidation of spatial
    memory,” Institute of Science and Technology Austria, 2018.
  ista: Gridchyn I. 2018. Reactivation content is important for consolidation of spatial
    memory. Institute of Science and Technology Austria.
  mla: Gridchyn, Igor. <i>Reactivation Content Is Important for Consolidation of Spatial
    Memory</i>. Institute of Science and Technology Austria, 2018, doi:<a href="https://doi.org/10.15479/AT:ISTA:th_1042">10.15479/AT:ISTA:th_1042</a>.
  short: I. Gridchyn, Reactivation Content Is Important for Consolidation of Spatial
    Memory, Institute of Science and Technology Austria, 2018.
corr_author: '1'
date_created: 2018-12-11T11:44:21Z
date_published: 2018-08-27T00:00:00Z
date_updated: 2026-04-08T14:13:15Z
day: '27'
ddc:
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degree_awarded: PhD
department:
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doi: 10.15479/AT:ISTA:th_1042
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month: '08'
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publisher: Institute of Science and Technology Austria
publist_id: '8006'
pubrep_id: '1042'
status: public
supervisor:
- first_name: Jozsef L
  full_name: Csicsvari, Jozsef L
  id: 3FA14672-F248-11E8-B48F-1D18A9856A87
  last_name: Csicsvari
  orcid: 0000-0002-5193-4036
title: Reactivation content is important for consolidation of spatial memory
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type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
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...
