--- OA_place: repository OA_type: green _id: '19502' abstract: - lang: eng text: Alkali dimers, Ak2, located on the surface of a helium nanodroplet, are set into rotation through the polarizability interaction with a nonresonant 1-ps-long laser pulse. The time-dependent degree of alignment is recorded using femtosecond-probe-pulse-induced Coulomb explosion into a pair of Ak+ fragment ions. The results, obtained for Na2, K2, and Rb2 in both the ground state 11Σ+g and the lowest-lying triplet state 13Σ+u, exhibit distinct, periodic revivals with a gradually decreasing amplitude. The dynamics differ from that expected for dimers had they behaved as free rotors. Numerically, we solve the time-dependent rotational Schrödinger equation, including an effective mean-field potential to describe the interaction between the dimer and the droplet. The experimental and simulated alignment dynamics agree well and their comparison enables us to determine the effective rotational constants of the alkali dimers with the exception of Rb2(13Σ+u) that only exhibits a prompt alignment peak but no subsequent revivals. For Na2(13Σ+u), K2(11Σ+g), K2(13Σ+u) and Rb2(11Σ+g), the alignment dynamics are well-described by a 2D rotor model. We ascribe this to a significant confinement of the internuclear axis of these dimers, induced by the orientation-dependent droplet-dimer interaction, to the tangential plane of their residence point on the droplet. acknowledgement: H.S. acknowledges support from the Villum Foundation through a Villum Investigator Grant No. 25886. We thank Jan Thøgersen for expert help with the optics and the laser system. article_number: '033114' article_processing_charge: No article_type: original arxiv: 1 author: - first_name: Henrik H. full_name: Kristensen, Henrik H. last_name: Kristensen - first_name: Lorenz full_name: Kranabetter, Lorenz last_name: Kranabetter - first_name: Areg full_name: Ghazaryan, Areg id: 4AF46FD6-F248-11E8-B48F-1D18A9856A87 last_name: Ghazaryan orcid: 0000-0001-9666-3543 - first_name: Constant A. full_name: Schouder, Constant A. last_name: Schouder - first_name: Emil full_name: Hansen, Emil last_name: Hansen - first_name: Frank full_name: Jensen, Frank last_name: Jensen - first_name: Robert E. full_name: Zillich, Robert E. last_name: Zillich - first_name: Mikhail full_name: Lemeshko, Mikhail id: 37CB05FA-F248-11E8-B48F-1D18A9856A87 last_name: Lemeshko orcid: 0000-0002-6990-7802 - first_name: Henrik full_name: Stapelfeldt, Henrik last_name: Stapelfeldt citation: ama: Kristensen HH, Kranabetter L, Ghazaryan A, et al. Nonadiabatic laser-induced alignment dynamics of alkali-metal dimers on the surface of a helium droplet. Physical Review A. 2025;111(3). doi:10.1103/PhysRevA.111.033114 apa: Kristensen, H. H., Kranabetter, L., Ghazaryan, A., Schouder, C. A., Hansen, E., Jensen, F., … Stapelfeldt, H. (2025). Nonadiabatic laser-induced alignment dynamics of alkali-metal dimers on the surface of a helium droplet. Physical Review A. American Physical Society. https://doi.org/10.1103/PhysRevA.111.033114 chicago: Kristensen, Henrik H., Lorenz Kranabetter, Areg Ghazaryan, Constant A. Schouder, Emil Hansen, Frank Jensen, Robert E. Zillich, Mikhail Lemeshko, and Henrik Stapelfeldt. “Nonadiabatic Laser-Induced Alignment Dynamics of Alkali-Metal Dimers on the Surface of a Helium Droplet.” Physical Review A. American Physical Society, 2025. https://doi.org/10.1103/PhysRevA.111.033114. ieee: H. H. Kristensen et al., “Nonadiabatic laser-induced alignment dynamics of alkali-metal dimers on the surface of a helium droplet,” Physical Review A, vol. 111, no. 3. American Physical Society, 2025. ista: Kristensen HH, Kranabetter L, Ghazaryan A, Schouder CA, Hansen E, Jensen F, Zillich RE, Lemeshko M, Stapelfeldt H. 2025. Nonadiabatic laser-induced alignment dynamics of alkali-metal dimers on the surface of a helium droplet. Physical Review A. 111(3), 033114. mla: Kristensen, Henrik H., et al. “Nonadiabatic Laser-Induced Alignment Dynamics of Alkali-Metal Dimers on the Surface of a Helium Droplet.” Physical Review A, vol. 111, no. 3, 033114, American Physical Society, 2025, doi:10.1103/PhysRevA.111.033114. short: H.H. Kristensen, L. Kranabetter, A. Ghazaryan, C.A. Schouder, E. Hansen, F. Jensen, R.E. Zillich, M. Lemeshko, H. Stapelfeldt, Physical Review A 111 (2025). date_created: 2025-04-06T22:01:32Z date_published: 2025-03-21T00:00:00Z date_updated: 2025-09-30T11:27:25Z day: '21' department: - _id: MiLe doi: 10.1103/PhysRevA.111.033114 external_id: arxiv: - '2502.14521' isi: - '001459727400007' intvolume: ' 111' isi: 1 issue: '3' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.48550/arXiv.2502.14521 month: '03' oa: 1 oa_version: Preprint publication: Physical Review A publication_identifier: eissn: - 2469-9934 issn: - 2469-9926 publication_status: published publisher: American Physical Society quality_controlled: '1' scopus_import: '1' status: public title: Nonadiabatic laser-induced alignment dynamics of alkali-metal dimers on the surface of a helium droplet type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 111 year: '2025' ... --- OA_place: publisher OA_type: hybrid _id: '19503' abstract: - lang: eng text: "A tantalizing open problem, posed independently by Stiebitz in 1995 and by Alon in 1996 and again in 2006, asks whether for every pair of integers s,t≥1 there exists a finite number F(s,t)\r\nsuch that the vertex set of every digraph of minimum out-degree at least F(s,t) can be partitioned into non-empty parts \ A and B such that the subdigraphs induced on A\r\n and B have minimum out-degree at least s and t , respectively.\r\nIn this short note, we prove that if F(2,2) exists, then all the numbers F(s,t) with s,t≥1\r\n exist and satisfy F(s,t)=Θ(s+t) . In consequence, the problem of Alon and Stiebitz reduces to the case s=t=2 . Moreover, the numbers F(s,t) with s,t≥2 either all exist and grow linearly, or all of them do not exist." acknowledgement: Funded by SNSF Ambizione grant No. 216071. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No, 101034413. Funded by SNSF grant CRSII5, 173721. article_processing_charge: Yes (in subscription journal) article_type: original arxiv: 1 author: - first_name: Micha full_name: Christoph, Micha last_name: Christoph - first_name: Kalina H full_name: Petrova, Kalina H id: 554ff4e4-f325-11ee-b0c4-a10dbd523381 last_name: Petrova - first_name: Raphael full_name: Steiner, Raphael last_name: Steiner citation: ama: Christoph M, Petrova KH, Steiner R. A note on digraph splitting. Combinatorics Probability and Computing. 2025;34(4):559-564. doi:10.1017/S0963548325000045 apa: Christoph, M., Petrova, K. H., & Steiner, R. (2025). A note on digraph splitting. Combinatorics Probability and Computing. Cambridge University Press. https://doi.org/10.1017/S0963548325000045 chicago: Christoph, Micha, Kalina H Petrova, and Raphael Steiner. “A Note on Digraph Splitting.” Combinatorics Probability and Computing. Cambridge University Press, 2025. https://doi.org/10.1017/S0963548325000045. ieee: M. Christoph, K. H. Petrova, and R. Steiner, “A note on digraph splitting,” Combinatorics Probability and Computing, vol. 34, no. 4. Cambridge University Press, pp. 559–564, 2025. ista: Christoph M, Petrova KH, Steiner R. 2025. A note on digraph splitting. Combinatorics Probability and Computing. 34(4), 559–564. mla: Christoph, Micha, et al. “A Note on Digraph Splitting.” Combinatorics Probability and Computing, vol. 34, no. 4, Cambridge University Press, 2025, pp. 559–64, doi:10.1017/S0963548325000045. short: M. Christoph, K.H. Petrova, R. Steiner, Combinatorics Probability and Computing 34 (2025) 559–564. date_created: 2025-04-06T22:01:32Z date_published: 2025-07-01T00:00:00Z date_updated: 2025-09-30T11:26:00Z day: '01' ddc: - '510' department: - _id: MaKw doi: 10.1017/S0963548325000045 ec_funded: 1 external_id: arxiv: - '2310.08449' isi: - '001449245700001' file: - access_level: open_access checksum: 98491e59b4f0d05d69f608bbd5706f1a content_type: application/pdf creator: dernst date_created: 2025-08-05T12:54:06Z date_updated: 2025-08-05T12:54:06Z file_id: '20135' file_name: 2025_CombProbComputing_Christoph.pdf file_size: 188818 relation: main_file success: 1 file_date_updated: 2025-08-05T12:54:06Z has_accepted_license: '1' intvolume: ' 34' isi: 1 issue: '4' language: - iso: eng license: https://creativecommons.org/licenses/by/4.0/ month: '07' oa: 1 oa_version: Published Version page: 559-564 project: - _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c call_identifier: H2020 grant_number: '101034413' name: 'IST-BRIDGE: International postdoctoral program' publication: Combinatorics Probability and Computing publication_identifier: eissn: - 1469-2163 issn: - 0963-5483 publication_status: published publisher: Cambridge University Press quality_controlled: '1' scopus_import: '1' status: public title: A note on digraph splitting tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 34 year: '2025' ... --- OA_place: publisher OA_type: hybrid _id: '19504' abstract: - lang: eng text: Observational studies have shown that galaxy disks were already in place in the first few billion years of the Universe. The early disks detected so far, with typical half-light radii of 3 kpc at stellar masses around 1011 M⊙ for redshift z ≈ 3, are significantly smaller than today’s disks with similar masses, which is in agreement with expectations from current galaxy models. Here we report observations of a giant disk at z = 3.25, when the Universe was only two billion years old, with a half-light radius of 9.6 kpc and stellar mass of (math formular). This galaxy is larger than any other kinematically confirmed disks at similar epochs and is surprisingly similar to today’s largest disks with regard to size and mass. James Webb Space Telescope imaging and spectroscopy reveal its spiral morphology and a rotational velocity consistent with a local Tully–Fisher relationship. Multiwavelength observations show that it lies in an exceptionally dense environment, where the galaxy number density is more than ten times higher than the cosmic average and mergers are frequent. The discovery of such a giant disk suggests the presence of favourable physical conditions for large-disk formation in dense environments in the early Universe, which may include efficient accretion of gas carrying coherent angular momentum and non-destructive mergers between exceptionally gas-rich progenitor galaxies. acknowledgement: We thank B. Wang, P. Madau, M. Dotti, A. de la Vega, Y. Guo, C. Bacchini, Z. Cai, C. Conselice, A. Dekel, S. Faber, F. Fraternali, L. Ho, F. Jiang, S. Kassin, D. Koo, N. Mandelker, S. Mao and D. Xu for the valuable and insightful discussions regarding the research topics relevant to this paper. This project was supported by the European Research Council (ERC) Consolidator Grant no. 864361 (CosmicWeb). A.P. acknowledges the support from Fondazione Cariplo grant no. 2020-0902. M.V.M. acknowledges funding from NASA by means of HST-GO-17065. T.N. acknowledges support from Australian Research Council Laureate Fellowship FL180100060. This work is based in part on observations made with the NASA/ESA/CSA James Webb Space Telescope. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with programme no. 1835. Support for programme no. 1835 was provided by NASA through a grant from the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127. This research is based on observations made with the NASA/ESA Hubble Space Telescope obtained from the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-26555. These observations are associated with programme 17065. ALMA is a partnership of ESO (representing its member states), NSF (USA) and NINS (Japan), together with NRC (Canada), MOST and ASIAA (Taiwan), and KASI (Republic of Korea), in cooperation with the Republic of Chile. The Joint ALMA Observatory is operated by ESO, AUI/NRAO and NAOJ. The scientific results reported in this article are based in part on observations made by the Chandra X-ray Observatory. This work is also based on observations collected at the European Southern Observatory under ESO programme 110.23ZX. article_processing_charge: No article_type: original arxiv: 1 author: - first_name: Weichen full_name: Wang, Weichen last_name: Wang - first_name: Sebastiano full_name: Cantalupo, Sebastiano last_name: Cantalupo - first_name: Antonio full_name: Pensabene, Antonio last_name: Pensabene - first_name: Marta full_name: Galbiati, Marta last_name: Galbiati - first_name: Andrea full_name: Travascio, Andrea last_name: Travascio - first_name: Charles C. full_name: Steidel, Charles C. last_name: Steidel - first_name: Michael V. full_name: Maseda, Michael V. last_name: Maseda - first_name: Gabriele full_name: Pezzulli, Gabriele last_name: Pezzulli - first_name: Stephanie full_name: De Beer, Stephanie last_name: De Beer - first_name: Matteo full_name: Fossati, Matteo last_name: Fossati - first_name: Michele full_name: Fumagalli, Michele last_name: Fumagalli - first_name: Sofia G. full_name: Gallego, Sofia G. last_name: Gallego - first_name: Titouan full_name: Lazeyras, Titouan last_name: Lazeyras - first_name: Ruari full_name: Mackenzie, Ruari last_name: Mackenzie - first_name: Jorryt J full_name: Matthee, Jorryt J id: 7439a258-f3c0-11ec-9501-9df22fe06720 last_name: Matthee orcid: 0000-0003-2871-127X - first_name: Themiya full_name: Nanayakkara, Themiya last_name: Nanayakkara - first_name: Giada full_name: Quadri, Giada last_name: Quadri citation: ama: Wang W, Cantalupo S, Pensabene A, et al. A giant disk galaxy two billion years after the Big Bang. Nature Astronomy. 2025;9:710-719. doi:10.1038/s41550-025-02500-2 apa: Wang, W., Cantalupo, S., Pensabene, A., Galbiati, M., Travascio, A., Steidel, C. C., … Quadri, G. (2025). A giant disk galaxy two billion years after the Big Bang. Nature Astronomy. Springer Nature. https://doi.org/10.1038/s41550-025-02500-2 chicago: Wang, Weichen, Sebastiano Cantalupo, Antonio Pensabene, Marta Galbiati, Andrea Travascio, Charles C. Steidel, Michael V. Maseda, et al. “A Giant Disk Galaxy Two Billion Years after the Big Bang.” Nature Astronomy. Springer Nature, 2025. https://doi.org/10.1038/s41550-025-02500-2. ieee: W. Wang et al., “A giant disk galaxy two billion years after the Big Bang,” Nature Astronomy, vol. 9. Springer Nature, pp. 710–719, 2025. ista: Wang W, Cantalupo S, Pensabene A, Galbiati M, Travascio A, Steidel CC, Maseda MV, Pezzulli G, De Beer S, Fossati M, Fumagalli M, Gallego SG, Lazeyras T, Mackenzie R, Matthee JJ, Nanayakkara T, Quadri G. 2025. A giant disk galaxy two billion years after the Big Bang. Nature Astronomy. 9, 710–719. mla: Wang, Weichen, et al. “A Giant Disk Galaxy Two Billion Years after the Big Bang.” Nature Astronomy, vol. 9, Springer Nature, 2025, pp. 710–19, doi:10.1038/s41550-025-02500-2. short: W. Wang, S. Cantalupo, A. Pensabene, M. Galbiati, A. Travascio, C.C. Steidel, M.V. Maseda, G. Pezzulli, S. De Beer, M. Fossati, M. Fumagalli, S.G. Gallego, T. Lazeyras, R. Mackenzie, J.J. Matthee, T. Nanayakkara, G. Quadri, Nature Astronomy 9 (2025) 710–719. date_created: 2025-04-06T22:01:32Z date_published: 2025-03-17T00:00:00Z date_updated: 2025-09-30T11:25:14Z day: '17' ddc: - '520' department: - _id: JoMa doi: 10.1038/s41550-025-02500-2 external_id: arxiv: - '2409.17956' isi: - '001447477100001' pmid: - '40417329' file: - access_level: open_access checksum: a0e65fe3374bd755b18ba03fd5e42a3f content_type: application/pdf creator: dernst date_created: 2025-08-05T12:49:36Z date_updated: 2025-08-05T12:49:36Z file_id: '20134' file_name: 2025_NatureAstronomy_Wang.pdf file_size: 4912850 relation: main_file success: 1 file_date_updated: 2025-08-05T12:49:36Z has_accepted_license: '1' intvolume: ' 9' isi: 1 language: - iso: eng license: https://creativecommons.org/licenses/by-nc-nd/4.0/ month: '03' oa: 1 oa_version: Published Version page: 710-719 pmid: 1 publication: Nature Astronomy publication_identifier: eissn: - 2397-3366 publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: A giant disk galaxy two billion years after the Big Bang tmp: image: /images/cc_by_nc_nd.png legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) short: CC BY-NC-ND (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 9 year: '2025' ... --- OA_place: repository OA_type: green _id: '19505' abstract: - lang: eng text: In this paper, we introduce and study the primitive equations with non-isothermal turbulent pressure and transport noise. They are derived from the Navier–Stokes equations by employing stochastic versions of the Boussinesq and the hydrostatic approximations. The temperature dependence of the turbulent pressure can be seen as a consequence of an additive noise acting on the small vertical dynamics. For such a model we prove global well-posedness in H^1 where the noise is considered in both the Itô and Stratonovich formulations. Compared to previous variants of the primitive equations, the one considered here presents a more intricate coupling between the velocity field and the temperature. The corresponding analysis is seriously more involved than in the deterministic setting. Finally, the continuous dependence on the initial data and the energy estimates proven here are new, even in the case of isothermal turbulent pressure. acknowledgement: "The first author thanks Umberto Pappalettera for helpful suggestions on Section 2 and for bringing to his attention the reference [56]. The first author is grateful to Marco Romito for helpful comments related to Remarks 2.1 and 2.2. Finally, the first author thanks Caterina Balzotti for her support in creating the picture.\r\nAntonio Agresti has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 948819). Antonio Agresti is a member of GNAMPA (INδAM).\r\nMatthias Hieber gratefully acknowledges the support by the Deutsche Forschungsgemeinschaft (DFG) through the Research Unit 5528—project number 500072446.\r\nAmru Hussein has been supported by Deutsche Forschungsgemeinschaft (DFG)—project\r\nnumber 508634462 and by MathApp—Mathematics Applied to Real-World Problems—part\r\nof the Research Initiative of the Federal State of Rhineland-Palatinate, Germany.\r\nMartin Saal has been supported by Deutsche Forschungsgemeinschaft (DFG)—project\r\nnumber 429483464." article_processing_charge: No article_type: original arxiv: 1 author: - first_name: Antonio full_name: Agresti, Antonio id: 673cd0cc-9b9a-11eb-b144-88f30e1fbb72 last_name: Agresti orcid: 0000-0002-9573-2962 - first_name: Matthias full_name: Hieber, Matthias last_name: Hieber - first_name: Amru full_name: Hussein, Amru last_name: Hussein - first_name: Martin full_name: Saal, Martin last_name: Saal citation: ama: Agresti A, Hieber M, Hussein A, Saal M. The stochastic primitive equations with nonisothermal turbulent pressure. Annals of Applied Probability. 2025;35(1):635-700. doi:10.1214/24-AAP2124 apa: Agresti, A., Hieber, M., Hussein, A., & Saal, M. (2025). The stochastic primitive equations with nonisothermal turbulent pressure. Annals of Applied Probability. Institute of Mathematical Statistics. https://doi.org/10.1214/24-AAP2124 chicago: Agresti, Antonio, Matthias Hieber, Amru Hussein, and Martin Saal. “The Stochastic Primitive Equations with Nonisothermal Turbulent Pressure.” Annals of Applied Probability. Institute of Mathematical Statistics, 2025. https://doi.org/10.1214/24-AAP2124. ieee: A. Agresti, M. Hieber, A. Hussein, and M. Saal, “The stochastic primitive equations with nonisothermal turbulent pressure,” Annals of Applied Probability, vol. 35, no. 1. Institute of Mathematical Statistics, pp. 635–700, 2025. ista: Agresti A, Hieber M, Hussein A, Saal M. 2025. The stochastic primitive equations with nonisothermal turbulent pressure. Annals of Applied Probability. 35(1), 635–700. mla: Agresti, Antonio, et al. “The Stochastic Primitive Equations with Nonisothermal Turbulent Pressure.” Annals of Applied Probability, vol. 35, no. 1, Institute of Mathematical Statistics, 2025, pp. 635–700, doi:10.1214/24-AAP2124. short: A. Agresti, M. Hieber, A. Hussein, M. Saal, Annals of Applied Probability 35 (2025) 635–700. date_created: 2025-04-06T22:01:32Z date_published: 2025-02-01T00:00:00Z date_updated: 2025-09-30T11:23:58Z day: '01' department: - _id: JuFi doi: 10.1214/24-AAP2124 ec_funded: 1 external_id: arxiv: - '2210.05973' isi: - '001434322900016' intvolume: ' 35' isi: 1 issue: '1' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.48550/arXiv.2210.05973 month: '02' oa: 1 oa_version: Preprint page: 635-700 project: - _id: 0aa76401-070f-11eb-9043-b5bb049fa26d call_identifier: H2020 grant_number: '948819' name: Bridging Scales in Random Materials publication: Annals of Applied Probability publication_identifier: issn: - 1050-5164 publication_status: published publisher: Institute of Mathematical Statistics quality_controlled: '1' scopus_import: '1' status: public title: The stochastic primitive equations with nonisothermal turbulent pressure type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 35 year: '2025' ... --- OA_place: publisher OA_type: hybrid PlanS_conform: '1' _id: '19506' abstract: - lang: eng text: 'Hippocampal reactivation of waking neuronal assemblies in sleep is a key initial step of systems consolidation. Nevertheless, it is unclear whether reactivated assemblies are static or whether they reorganize gradually over prolonged sleep. We tracked reactivated CA1 assembly patterns over ∼20 h of sleep/rest periods and related them to assemblies seen before or after in a spatial learning paradigm using rats. We found that reactivated assembly patterns were gradually transformed and started to resemble those seen in the subsequent recall session. Periods of rapid eye movement (REM) sleep and non-REM (NREM) had antagonistic roles: whereas NREM accelerated the assembly drift, REM countered it. Moreover, only a subset of rate-changing pyramidal cells contributed to the drift, whereas stable-firing-rate cells maintained unaltered reactivation patterns. Our data suggest that prolonged sleep promotes the spontaneous reorganization of spatial assemblies, which can contribute to daily cognitive map changes or encoding new learning situations.' acknowledgement: We thank Andrea Cumpelik, Lisa Genzel, and Freya Ólafsdóttir for comments on an earlier version of the manuscript. This work was supported by the European Research Council (281511) and Austrian Science Fund (FWF I3713). article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Lars full_name: Bollmann, Lars id: 47AD3038-F248-11E8-B48F-1D18A9856A87 last_name: Bollmann - first_name: Peter full_name: Baracskay, Peter id: 361CC00E-F248-11E8-B48F-1D18A9856A87 last_name: Baracskay - first_name: Federico full_name: Stella, Federico id: 39AF1E74-F248-11E8-B48F-1D18A9856A87 last_name: Stella orcid: 0000-0001-9439-3148 - first_name: Jozsef L full_name: Csicsvari, Jozsef L id: 3FA14672-F248-11E8-B48F-1D18A9856A87 last_name: Csicsvari orcid: 0000-0002-5193-4036 citation: ama: Bollmann L, Baracskay P, Stella F, Csicsvari JL. Sleep stages antagonistically modulate reactivation drift. Neuron. 2025;113(9):1446-1459.e6. doi:10.1016/j.neuron.2025.02.025 apa: Bollmann, L., Baracskay, P., Stella, F., & Csicsvari, J. L. (2025). Sleep stages antagonistically modulate reactivation drift. Neuron. Elsevier. https://doi.org/10.1016/j.neuron.2025.02.025 chicago: Bollmann, Lars, Peter Baracskay, Federico Stella, and Jozsef L Csicsvari. “Sleep Stages Antagonistically Modulate Reactivation Drift.” Neuron. Elsevier, 2025. https://doi.org/10.1016/j.neuron.2025.02.025. ieee: L. Bollmann, P. Baracskay, F. Stella, and J. L. Csicsvari, “Sleep stages antagonistically modulate reactivation drift,” Neuron, vol. 113, no. 9. Elsevier, p. 1446–1459.e6, 2025. ista: Bollmann L, Baracskay P, Stella F, Csicsvari JL. 2025. Sleep stages antagonistically modulate reactivation drift. Neuron. 113(9), 1446–1459.e6. mla: Bollmann, Lars, et al. “Sleep Stages Antagonistically Modulate Reactivation Drift.” Neuron, vol. 113, no. 9, Elsevier, 2025, p. 1446–1459.e6, doi:10.1016/j.neuron.2025.02.025. short: L. Bollmann, P. Baracskay, F. Stella, J.L. Csicsvari, Neuron 113 (2025) 1446–1459.e6. corr_author: '1' date_created: 2025-04-06T22:01:32Z date_published: 2025-05-07T00:00:00Z date_updated: 2026-04-28T13:39:22Z day: '07' ddc: - '570' department: - _id: JoCs doi: 10.1016/j.neuron.2025.02.025 ec_funded: 1 external_id: isi: - '001510440400001' pmid: - '40132588' file: - access_level: open_access checksum: 5e57852a45a78a751dd3a5e807bf015f content_type: application/pdf creator: dernst date_created: 2025-08-05T12:43:44Z date_updated: 2025-08-05T12:43:44Z file_id: '20133' file_name: 2025_Neuron_Bollmann.pdf file_size: 27047730 relation: main_file success: 1 file_date_updated: 2025-08-05T12:43:44Z has_accepted_license: '1' intvolume: ' 113' isi: 1 issue: '9' language: - iso: eng month: '05' oa: 1 oa_version: Published Version page: 1446-1459.e6 pmid: 1 project: - _id: 257A4776-B435-11E9-9278-68D0E5697425 call_identifier: FP7 grant_number: '281511' name: Memory-related information processing in neuronal circuits of the hippocampus and entorhinal cortex - _id: 2654F984-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: I 3713-B27 name: Interneuro plasticity during spatial learning publication: Neuron publication_identifier: eissn: - 1097-4199 issn: - 0896-6273 publication_status: published publisher: Elsevier quality_controlled: '1' related_material: link: - description: News on ISTA website relation: press_release url: https://ista.ac.at/en/news/how-sleep-keeps-our-memories-fresh/ scopus_import: '1' status: public title: Sleep stages antagonistically modulate reactivation drift tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd volume: 113 year: '2025' ... --- OA_place: publisher OA_type: hybrid _id: '19507' abstract: - lang: eng text: The epidermis provides a protective barrier against hostile environments. However, our knowledge of how this barrier forms during development and is subsequently maintained remains incomplete. The infundibulum is a cylindrical epidermal tissue compartment that serves as an outlet for hair follicles protruding from the skin and the excretion of the sebaceous glands that are essential for proper skin function. In this study, we applied quantitative fate mapping to address how infundibulum are maintained during adulthood. We demonstrate that progenitors build and maintain tissues through stochastic cell fate choices. Long-term analysis identified a preferential transient contribution from cells initially located at the bottom of the structure to the maintenance of the tissue, with bursts of local progenitor expansion associated with the phases of hair growth. Beyond providing compartment-wide insights into progenitor cell dynamics in infundibulum, these findings demonstrate how spatiotemporal regulation controls transient progenitor dominance. acknowledgement: We thank the members of the Jensen Laboratory for experimental and technical advice, the imaging facilities at reNEW, and animal caretakers for expert assistance. This work was supported by the Lundbeck Foundation (R105-A9755 to KBJ) and the Leo Pharma Foundation (LF-OC-20-000169). The Novo Nordisk Foundation Center for Stem Cell Medicine was supported by a Novo Nordisk Foundation grant (NNF21CC0073729). B.D.S. was supported by the Wellcome Trust (219478/Z/19/Z) and a Royal Society EP Abraham Research Professorship (RP/R1/180165 and RP\R\231004). Figure elements were adapted from Bio-Render. KBJ is the lead contact and guarantor of this study. article_processing_charge: No article_type: original author: - first_name: Marianne S. full_name: Andersen, Marianne S. last_name: Andersen - first_name: Svetlana full_name: Ulyanchenko, Svetlana last_name: Ulyanchenko - first_name: Pawel J. full_name: Schweiger, Pawel J. last_name: Schweiger - first_name: Edouard B full_name: Hannezo, Edouard B id: 3A9DB764-F248-11E8-B48F-1D18A9856A87 last_name: Hannezo orcid: 0000-0001-6005-1561 - first_name: Benjamin D. full_name: Simons, Benjamin D. last_name: Simons - first_name: Kim B. full_name: Jensen, Kim B. last_name: Jensen citation: ama: Andersen MS, Ulyanchenko S, Schweiger PJ, Hannezo EB, Simons BD, Jensen KB. Spatiotemporal switches in progenitor cell fate govern upper hair follicle growth and maintenance. Journal of Investigative Dermatology. 2025;145(9):2191-2202.e5. doi:10.1016/j.jid.2025.01.034 apa: Andersen, M. S., Ulyanchenko, S., Schweiger, P. J., Hannezo, E. B., Simons, B. D., & Jensen, K. B. (2025). Spatiotemporal switches in progenitor cell fate govern upper hair follicle growth and maintenance. Journal of Investigative Dermatology. Elsevier. https://doi.org/10.1016/j.jid.2025.01.034 chicago: Andersen, Marianne S., Svetlana Ulyanchenko, Pawel J. Schweiger, Edouard B Hannezo, Benjamin D. Simons, and Kim B. Jensen. “Spatiotemporal Switches in Progenitor Cell Fate Govern Upper Hair Follicle Growth and Maintenance.” Journal of Investigative Dermatology. Elsevier, 2025. https://doi.org/10.1016/j.jid.2025.01.034. ieee: M. S. Andersen, S. Ulyanchenko, P. J. Schweiger, E. B. Hannezo, B. D. Simons, and K. B. Jensen, “Spatiotemporal switches in progenitor cell fate govern upper hair follicle growth and maintenance,” Journal of Investigative Dermatology, vol. 145, no. 9. Elsevier, p. 2191–2202.e5, 2025. ista: Andersen MS, Ulyanchenko S, Schweiger PJ, Hannezo EB, Simons BD, Jensen KB. 2025. Spatiotemporal switches in progenitor cell fate govern upper hair follicle growth and maintenance. Journal of Investigative Dermatology. 145(9), 2191–2202.e5. mla: Andersen, Marianne S., et al. “Spatiotemporal Switches in Progenitor Cell Fate Govern Upper Hair Follicle Growth and Maintenance.” Journal of Investigative Dermatology, vol. 145, no. 9, Elsevier, 2025, p. 2191–2202.e5, doi:10.1016/j.jid.2025.01.034. short: M.S. Andersen, S. Ulyanchenko, P.J. Schweiger, E.B. Hannezo, B.D. Simons, K.B. Jensen, Journal of Investigative Dermatology 145 (2025) 2191–2202.e5. corr_author: '1' date_created: 2025-04-06T22:01:32Z date_published: 2025-09-01T00:00:00Z date_updated: 2025-12-29T14:13:43Z day: '01' ddc: - '570' department: - _id: EdHa doi: 10.1016/j.jid.2025.01.034 external_id: isi: - '001604396400001' pmid: - '40010488' file: - access_level: open_access checksum: a2b313de3cacb53f20f2b91c42612ad9 content_type: application/pdf creator: dernst date_created: 2025-12-29T14:13:01Z date_updated: 2025-12-29T14:13:01Z file_id: '20874' file_name: 2025_JourInvestigativeDerma_Andersen.pdf file_size: 7301679 relation: main_file success: 1 file_date_updated: 2025-12-29T14:13:01Z has_accepted_license: '1' intvolume: ' 145' isi: 1 issue: '9' language: - iso: eng month: '09' oa: 1 oa_version: Published Version page: 2191-2202.e5 pmid: 1 publication: Journal of Investigative Dermatology publication_identifier: eissn: - 1523-1747 issn: - 0022-202X publication_status: published publisher: Elsevier quality_controlled: '1' scopus_import: '1' status: public title: Spatiotemporal switches in progenitor cell fate govern upper hair follicle growth and maintenance tmp: image: /images/cc_by_nc_nd.png legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) short: CC BY-NC-ND (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 145 year: '2025' ... --- OA_place: publisher OA_type: hybrid PlanS_conform: '1' _id: '19508' abstract: - lang: eng text: We consider random two-player zero-sum dynamic games with perfect information on a class of infinite directed graphs. Starting from a fixed vertex, the players take turns to move a token along the edges of the graph. Every vertex is assigned a payoff known in advance by both players. Every time the token visits a vertex, Player 2 pays Player 1 the corresponding payoff. We consider a distribution over such games by assigning i.i.d. payoffs to the vertices. On the one hand, for acyclic directed graphs of bounded degree and sub-exponential expansion, we show that, when the duration of the game tends to infinity, the value converges almost surely to a constant at an exponential rate dominated in terms of the expansion. On the other hand, for the infinite d-ary tree (that does not fall into the previous class of graphs), we show convergence at a double-exponential rate. acknowledgement: Open access funding provided by Institute of Science and Technology (IST Austria). This work was supported by the French Agence Nationale de la Recherche (ANR) under references ANR-21-CE40-0020 (CONVERGENCE project) and ANR-20-CE40-0002 (GrHyDy), by Fondecyt grant 1220174, by ANID Chile grant ACT210005, and by the ERC CoG 863818 (ForM-SMArt) grant. This collaboration was mainly conducted during a 1-year visit of Bruno Ziliotto to the Center for Mathematical Modeling (CMM) at University of Chile in 2023, under the IRL program of CNRS. This work was supported by Fondation CFM pour la Recherche. This paper has also been funded by the Agence Nationale de la Recherche under grant ANR-17-EURE-0010 (Investissements d’Avenir program). article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Luc full_name: Attia, Luc last_name: Attia - first_name: Lyuben full_name: Lichev, Lyuben id: 9aa8388e-d003-11ee-8458-c4c1d7447977 last_name: Lichev - first_name: Dieter full_name: Mitsche, Dieter last_name: Mitsche - first_name: Raimundo J full_name: Saona Urmeneta, Raimundo J id: BD1DF4C4-D767-11E9-B658-BC13E6697425 last_name: Saona Urmeneta orcid: 0000-0001-5103-038X - first_name: Bruno full_name: Ziliotto, Bruno last_name: Ziliotto citation: ama: Attia L, Lichev L, Mitsche D, Saona Urmeneta RJ, Ziliotto B. Random zero-sum dynamic games on infinite directed graphs. Dynamic Games and Applications. 2025;15:1517-1535. doi:10.1007/s13235-025-00636-4 apa: Attia, L., Lichev, L., Mitsche, D., Saona Urmeneta, R. J., & Ziliotto, B. (2025). Random zero-sum dynamic games on infinite directed graphs. Dynamic Games and Applications. Springer Nature. https://doi.org/10.1007/s13235-025-00636-4 chicago: Attia, Luc, Lyuben Lichev, Dieter Mitsche, Raimundo J Saona Urmeneta, and Bruno Ziliotto. “Random Zero-Sum Dynamic Games on Infinite Directed Graphs.” Dynamic Games and Applications. Springer Nature, 2025. https://doi.org/10.1007/s13235-025-00636-4. ieee: L. Attia, L. Lichev, D. Mitsche, R. J. Saona Urmeneta, and B. Ziliotto, “Random zero-sum dynamic games on infinite directed graphs,” Dynamic Games and Applications, vol. 15. Springer Nature, pp. 1517–1535, 2025. ista: Attia L, Lichev L, Mitsche D, Saona Urmeneta RJ, Ziliotto B. 2025. Random zero-sum dynamic games on infinite directed graphs. Dynamic Games and Applications. 15, 1517–1535. mla: Attia, Luc, et al. “Random Zero-Sum Dynamic Games on Infinite Directed Graphs.” Dynamic Games and Applications, vol. 15, Springer Nature, 2025, pp. 1517–35, doi:10.1007/s13235-025-00636-4. short: L. Attia, L. Lichev, D. Mitsche, R.J. Saona Urmeneta, B. Ziliotto, Dynamic Games and Applications 15 (2025) 1517–1535. corr_author: '1' date_created: 2025-04-06T22:01:32Z date_published: 2025-11-01T00:00:00Z date_updated: 2026-04-07T12:31:21Z day: '01' ddc: - '000' department: - _id: MaKw - _id: KrCh doi: 10.1007/s13235-025-00636-4 ec_funded: 1 external_id: isi: - '001449708900001' file: - access_level: open_access checksum: b3a1b7eef40c9ac2acf3fef563081694 content_type: application/pdf creator: dernst date_created: 2025-12-30T08:13:04Z date_updated: 2025-12-30T08:13:04Z file_id: '20891' file_name: 2025_DynGamesAppl_Attia.pdf file_size: 570994 relation: main_file success: 1 file_date_updated: 2025-12-30T08:13:04Z has_accepted_license: '1' intvolume: ' 15' isi: 1 language: - iso: eng month: '11' oa: 1 oa_version: Published Version page: 1517-1535 project: - _id: 0599E47C-7A3F-11EA-A408-12923DDC885E call_identifier: H2020 grant_number: '863818' name: 'Formal Methods for Stochastic Models: Algorithms and Applications' publication: Dynamic Games and Applications publication_identifier: eissn: - 2153-0793 issn: - 2153-0785 publication_status: published publisher: Springer Nature quality_controlled: '1' related_material: record: - id: '20234' relation: dissertation_contains status: public scopus_import: '1' status: public title: Random zero-sum dynamic games on infinite directed graphs tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 15 year: '2025' ... --- DOAJ_listed: '1' OA_place: publisher OA_type: gold _id: '19529' abstract: - lang: eng text: NRF2 is a transcription factor responsible for coordinating the expression of over a thousand cytoprotective genes. Although NRF2 is constitutively expressed, its stability is modulated by the redox-sensitive protein KEAP1 and other conditional binding partner regulators. The new era of NRF2 research has highlighted the cooperation between NRF2 and PIN1 in modifying its cytoprotective effect. Despite numerous studies, the understanding of the PIN1-NRF2 interaction remains limited. Herein, we described the binding interaction of PIN1 and three different 14-mer long phospho-peptides mimicking NRF2 protein using computer-based, biophysical, and biochemical approaches. According to our computational analyses, the residues positioned in the WW domain of PIN1 (Ser16, Arg17, Ser18, Tyr23, Ser32, Gln33, and Trp34) were found to be crucial for PIN1-NRF2 interactions. Biophysical FP assays were used to verify the computational prediction. The data demonstrated that Pintide, a peptide predominantly interacting with the PIN1 WW-domain, led to a significant reduction in the binding affinity of the NRF2 mimicking peptides. Moreover, we evaluated the impact of known PIN1 inhibitors (juglone, KPT-6566, and EGCG) on the PIN1-NRF2 interaction. Among the inhibitors, KPT-6566 showed the most potent inhibitory effect on PIN1-NRF2 interaction within an IC50 range of 0.3–1.4 µM. Furthermore, our mass spectrometry analyses showed that KPT-6566 appeared to covalently modify PIN1 via conjugate addition, rather than disulfide exchange of the sulfonyl-acetate moiety. Altogether, such inhibitors would also be highly valuable molecular probes for further investigation of PIN1 regulation of NRF2 in the cellular context and potentially pave the way for drug molecules that specifically inhibit the cytoprotective effects of NRF2 in cancer. acknowledgement: The authors would like to thank the Ministry of National Education of Republic of Türkiye within the scope of the YLSY scholarship program for funding (AO). This article is based upon work from COST Action CA20121, supported by COST (European Cooperation in Science and Technology) (www.cost.eu) (https://benbedphar.org/about-benbedphar/). The molecular dynamics simulations reported in this paper were performed at TUBITAK ULAKBIM, High Performance and Grid Computing Center (TRUBA resources). The authors thank Dr Sharad Mistry for his support in acquiring and processing the MS data. article_number: '8907' article_processing_charge: Yes article_type: original author: - first_name: Adem full_name: Ozleyen, Adem last_name: Ozleyen - first_name: Gizem Nur full_name: Duran, Gizem Nur last_name: Duran - first_name: Serhat full_name: Dönmez, Serhat id: 7c624079-3200-11ee-973b-9fcc8a575580 last_name: Dönmez - first_name: Mehmet full_name: Ozbil, Mehmet last_name: Ozbil - first_name: Richard G. full_name: Doveston, Richard G. last_name: Doveston - first_name: Tugba Boyunegmez full_name: Tumer, Tugba Boyunegmez last_name: Tumer citation: ama: Ozleyen A, Duran GN, Dönmez S, Ozbil M, Doveston RG, Tumer TB. Identification and inhibition of PIN1-NRF2 protein–protein interactions through computational and biophysical approaches. Scientific Reports. 2025;15. doi:10.1038/s41598-025-89342-0 apa: Ozleyen, A., Duran, G. N., Dönmez, S., Ozbil, M., Doveston, R. G., & Tumer, T. B. (2025). Identification and inhibition of PIN1-NRF2 protein–protein interactions through computational and biophysical approaches. Scientific Reports. Springer Nature. https://doi.org/10.1038/s41598-025-89342-0 chicago: Ozleyen, Adem, Gizem Nur Duran, Serhat Dönmez, Mehmet Ozbil, Richard G. Doveston, and Tugba Boyunegmez Tumer. “Identification and Inhibition of PIN1-NRF2 Protein–Protein Interactions through Computational and Biophysical Approaches.” Scientific Reports. Springer Nature, 2025. https://doi.org/10.1038/s41598-025-89342-0. ieee: A. Ozleyen, G. N. Duran, S. Dönmez, M. Ozbil, R. G. Doveston, and T. B. Tumer, “Identification and inhibition of PIN1-NRF2 protein–protein interactions through computational and biophysical approaches,” Scientific Reports, vol. 15. Springer Nature, 2025. ista: Ozleyen A, Duran GN, Dönmez S, Ozbil M, Doveston RG, Tumer TB. 2025. Identification and inhibition of PIN1-NRF2 protein–protein interactions through computational and biophysical approaches. Scientific Reports. 15, 8907. mla: Ozleyen, Adem, et al. “Identification and Inhibition of PIN1-NRF2 Protein–Protein Interactions through Computational and Biophysical Approaches.” Scientific Reports, vol. 15, 8907, Springer Nature, 2025, doi:10.1038/s41598-025-89342-0. short: A. Ozleyen, G.N. Duran, S. Dönmez, M. Ozbil, R.G. Doveston, T.B. Tumer, Scientific Reports 15 (2025). date_created: 2025-04-08T11:12:20Z date_published: 2025-03-14T00:00:00Z date_updated: 2025-09-30T11:33:37Z day: '14' ddc: - '570' department: - _id: LeSa doi: 10.1038/s41598-025-89342-0 external_id: isi: - '001445507400002' pmid: - '40087364' file: - access_level: open_access checksum: 6124a10402a67b66364cfa9350d35b4b content_type: application/pdf creator: dernst date_created: 2025-04-10T06:21:11Z date_updated: 2025-04-10T06:21:11Z file_id: '19537' file_name: 2025_ScientificReports_Ozleyen.pdf file_size: 5333058 relation: main_file success: 1 file_date_updated: 2025-04-10T06:21:11Z has_accepted_license: '1' intvolume: ' 15' isi: 1 language: - iso: eng month: '03' oa: 1 oa_version: Published Version pmid: 1 publication: Scientific Reports publication_identifier: eissn: - 2045-2322 publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: Identification and inhibition of PIN1-NRF2 protein–protein interactions through computational and biophysical approaches tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 15 year: '2025' ... --- APC_amount: 3054 EUR DOAJ_listed: '1' OA_place: publisher OA_type: gold _id: '19531' abstract: - lang: eng text: In standard quantum electrodynamics (QED), the so-called non-minimal (Pauli) coupling is suppressed for elementary particles and has no physical implications. Here, we show that the Pauli term naturally appears in a known family of Dirac materials—the lead-halide perovskites, suggesting a novel playground for the study of analog QED effects. We outline measurable manifestations of the Pauli term in the phenomena pertaining to (i) relativistic corrections to bound states (ii) the Klein paradox, and (iii) spin effects in scattering. In particular, we demonstrate that (a) the binding energy of an electron in the vicinity of a positively charged defect is noticeably decreased due to the polarizability of lead ions and the appearance of a Darwin-like term, (b) strong spin-orbit coupling due to the Pauli term affects the exciton states, and (c) scattering of an electron off an energy barrier with broken mirror symmetry produces spin polarization in the outgoing current. Our study adds to the understanding of quantum phenomena in lead-halide perovskites and paves the way for tabletop simulations of analog Dirac-Pauli equations. article_number: '37' article_processing_charge: Yes article_type: original author: - first_name: Abhishek full_name: Shiva Kumar, Abhishek id: 5e9a6931-eb97-11eb-a6c2-e96f7058d77a last_name: Shiva Kumar - first_name: Mikhail full_name: Maslov, Mikhail id: 2E65BB0E-F248-11E8-B48F-1D18A9856A87 last_name: Maslov orcid: 0000-0003-4074-2570 - first_name: Mikhail full_name: Lemeshko, Mikhail id: 37CB05FA-F248-11E8-B48F-1D18A9856A87 last_name: Lemeshko orcid: 0000-0002-6990-7802 - first_name: Artem full_name: Volosniev, Artem id: 37D278BC-F248-11E8-B48F-1D18A9856A87 last_name: Volosniev orcid: 0000-0003-0393-5525 - first_name: Zhanybek full_name: Alpichshev, Zhanybek id: 45E67A2A-F248-11E8-B48F-1D18A9856A87 last_name: Alpichshev orcid: 0000-0002-7183-5203 citation: ama: Shiva Kumar A, Maslov M, Lemeshko M, Volosniev A, Alpichshev Z. Massive Dirac-Pauli physics in lead-halide perovskites. npj Quantum Materials. 2025;10. doi:10.1038/s41535-025-00754-7 apa: Shiva Kumar, A., Maslov, M., Lemeshko, M., Volosniev, A., & Alpichshev, Z. (2025). Massive Dirac-Pauli physics in lead-halide perovskites. Npj Quantum Materials. Springer Nature. https://doi.org/10.1038/s41535-025-00754-7 chicago: Shiva Kumar, Abhishek, Mikhail Maslov, Mikhail Lemeshko, Artem Volosniev, and Zhanybek Alpichshev. “Massive Dirac-Pauli Physics in Lead-Halide Perovskites.” Npj Quantum Materials. Springer Nature, 2025. https://doi.org/10.1038/s41535-025-00754-7. ieee: A. Shiva Kumar, M. Maslov, M. Lemeshko, A. Volosniev, and Z. Alpichshev, “Massive Dirac-Pauli physics in lead-halide perovskites,” npj Quantum Materials, vol. 10. Springer Nature, 2025. ista: Shiva Kumar A, Maslov M, Lemeshko M, Volosniev A, Alpichshev Z. 2025. Massive Dirac-Pauli physics in lead-halide perovskites. npj Quantum Materials. 10, 37. mla: Shiva Kumar, Abhishek, et al. “Massive Dirac-Pauli Physics in Lead-Halide Perovskites.” Npj Quantum Materials, vol. 10, 37, Springer Nature, 2025, doi:10.1038/s41535-025-00754-7. short: A. Shiva Kumar, M. Maslov, M. Lemeshko, A. Volosniev, Z. Alpichshev, Npj Quantum Materials 10 (2025). corr_author: '1' date_created: 2025-04-08T18:13:06Z date_published: 2025-04-04T00:00:00Z date_updated: 2026-05-06T13:06:08Z day: '04' ddc: - '530' department: - _id: GradSch - _id: ZhAl - _id: MiLe doi: 10.1038/s41535-025-00754-7 external_id: isi: - '001459830100002' file: - access_level: open_access checksum: 08b1a94b362bb65482887e50020810e5 content_type: application/pdf creator: dernst date_created: 2025-04-10T06:12:49Z date_updated: 2025-04-10T06:12:49Z file_id: '19536' file_name: 2025_njpQuantumMaterials_Kumar.pdf file_size: 592092 relation: main_file success: 1 file_date_updated: 2025-04-10T06:12:49Z has_accepted_license: '1' intvolume: ' 10' isi: 1 language: - iso: eng month: '04' oa: 1 oa_version: Published Version project: - _id: B67AFEDC-15C9-11EA-A837-991A96BB2854 name: IST Austria Open Access Fund publication: npj Quantum Materials publication_identifier: eissn: - 2397-4648 publication_status: published publisher: Springer Nature quality_controlled: '1' related_material: link: - relation: software url: https://git.ista.ac.at/mmaslov/dirac_pauli_LHP scopus_import: '1' status: public title: Massive Dirac-Pauli physics in lead-halide perovskites tmp: image: /images/cc_by_nc_nd.png legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) short: CC BY-NC-ND (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 10 year: '2025' ... --- OA_place: publisher _id: '19540' abstract: - lang: eng text: "This thesis deals with several different models for complex quantum mechanical systems and is structured in three main parts. \r\n\t\r\nIn Part I, we study mean field random matrices as models for quantum Hamiltonians. Our focus lies on proving concentration estimates for resolvents of random matrices, so-called local laws, mostly in the setting of multiple resolvents. These estimates have profound consequences for eigenvector overlaps and thermalization problems. More concretely, we obtain, e.g., the optimal eigenstate thermalization hypothesis (ETH) uniformly in the spectrum for Wigner matrices, an optimal lower bound on non-Hermitian eigenvector overlaps, and prethermalization for deformed Wigner matrices.\tIn order to prove our novel multi-resolvent local laws, we develop and devise two main methods, the static Psi-method and the dynamical Zigzag strategy. \r\n\t\r\nIn Part II, we study Bardeen-Cooper-Schrieffer (BCS) theory, the standard mean field microscopic theory of superconductivity. We focus on asymptotic formulas for the characteristic critical temperature and energy gap of a superconductor and prove universality of their ratio in various physical regimes. Additionally, we investigate multi-band superconductors and show that inter-band coupling effects can only enhance the critical temperature. \r\n\t\r\nIn Part III, we study quantum lattice systems. On the one hand, we show a strong version of the local-perturbations-perturb-locally (LPPL) principle for the ground state of weakly interacting quantum spin systems with a uniform on-site gap. On the other hand, we introduce a notion of a local gap and rigorously justify response theory and the Kubo formula under the weakened assumption of a local gap. \r\n\t\r\nAdditionally, we discuss two classes of problems which do not fit into the three main parts of the thesis. These are deformational rigidity of Liouville metrics on the torus and relativistic toy models of particle creation via interior-boundary-conditions (IBCs). " alternative_title: - ISTA Thesis article_processing_charge: No author: - first_name: Sven Joscha full_name: Henheik, Sven Joscha id: 31d731d7-d235-11ea-ad11-b50331c8d7fb last_name: Henheik orcid: 0000-0003-1106-327X citation: ama: 'Henheik SJ. Modeling complex quantum systems : Random matrices, BCS theory, and quantum lattice systems. 2025. doi:10.15479/AT-ISTA-19540' apa: 'Henheik, S. J. (2025). Modeling complex quantum systems : Random matrices, BCS theory, and quantum lattice systems. Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-19540' chicago: 'Henheik, Sven Joscha. “Modeling Complex Quantum Systems : Random Matrices, BCS Theory, and Quantum Lattice Systems.” Institute of Science and Technology Austria, 2025. https://doi.org/10.15479/AT-ISTA-19540.' ieee: 'S. J. Henheik, “Modeling complex quantum systems : Random matrices, BCS theory, and quantum lattice systems,” Institute of Science and Technology Austria, 2025.' ista: 'Henheik SJ. 2025. Modeling complex quantum systems : Random matrices, BCS theory, and quantum lattice systems. Institute of Science and Technology Austria.' mla: 'Henheik, Sven Joscha. Modeling Complex Quantum Systems : Random Matrices, BCS Theory, and Quantum Lattice Systems. Institute of Science and Technology Austria, 2025, doi:10.15479/AT-ISTA-19540.' short: 'S.J. Henheik, Modeling Complex Quantum Systems : Random Matrices, BCS Theory, and Quantum Lattice Systems, Institute of Science and Technology Austria, 2025.' corr_author: '1' date_created: 2025-04-10T21:21:18Z date_published: 2025-04-10T00:00:00Z date_updated: 2026-04-07T12:37:12Z day: '10' ddc: - '519' degree_awarded: PhD department: - _id: GradSch - _id: LaEr doi: 10.15479/AT-ISTA-19540 ec_funded: 1 file: - access_level: closed checksum: b8477ae5578436c72c3bb4193ad34ac5 content_type: application/zip creator: shenheik date_created: 2025-04-10T21:14:18Z date_updated: 2025-04-10T21:14:18Z file_id: '19542' file_name: Henheik-Thesis_source_final.zip file_size: 4107587 relation: source_file - access_level: open_access checksum: e9fc0ea12ec46c9f71110c33217c4140 content_type: application/pdf creator: shenheik date_created: 2025-04-11T13:16:05Z date_updated: 2025-04-11T13:16:05Z file_id: '19553' file_name: Henheik-Thesis-pdfa_FINAL.pdf file_size: 9999492 relation: main_file success: 1 - access_level: closed checksum: f94580f86c785e7108eb116cd189e225 content_type: application/pdf creator: cchlebak date_created: 2025-04-23T14:10:27Z date_updated: 2025-04-23T14:10:27Z file_id: '19615' file_name: Henheik-Thesis-Volume1_print.pdf file_size: 13276442 relation: other - access_level: closed checksum: b927ead3c78020ffb32918911deedb74 content_type: application/pdf creator: cchlebak date_created: 2025-04-23T14:11:05Z date_updated: 2025-04-23T14:11:05Z file_id: '19616' file_name: Henheik-Thesis-Volume2_print.pdf file_size: 7628767 relation: other file_date_updated: 2025-04-23T14:11:05Z has_accepted_license: '1' language: - iso: eng month: '04' oa: 1 oa_version: Published Version page: '720' project: - _id: 62796744-2b32-11ec-9570-940b20777f1d call_identifier: H2020 grant_number: '101020331' name: Random matrices beyond Wigner-Dyson-Mehta publication_identifier: isbn: - 978-3-99078-057-2 issn: - 2663-337X publication_status: published publisher: Institute of Science and Technology Austria related_material: record: - id: '14343' relation: part_of_dissertation status: public - id: '18656' relation: part_of_dissertation status: public - id: '13317' relation: part_of_dissertation status: public - id: '11732' relation: part_of_dissertation status: public - id: '12184' relation: part_of_dissertation status: public - id: '14421' relation: part_of_dissertation status: public - id: '10623' relation: part_of_dissertation status: public - id: '18112' relation: part_of_dissertation status: public - id: '19001' relation: part_of_dissertation status: public - id: '10642' relation: part_of_dissertation status: public - id: '19545' relation: part_of_dissertation status: public - id: '19546' relation: part_of_dissertation status: public - id: '19550' relation: part_of_dissertation status: public - id: '19551' relation: part_of_dissertation status: public - id: '19552' relation: part_of_dissertation status: public - id: '14542' relation: part_of_dissertation status: public - id: '17049' relation: part_of_dissertation status: public - id: '18764' relation: part_of_dissertation status: public - id: '19547' relation: part_of_dissertation status: public - id: '19548' relation: part_of_dissertation status: public status: public supervisor: - first_name: László full_name: Erdös, László id: 4DBD5372-F248-11E8-B48F-1D18A9856A87 last_name: Erdös orcid: 0000-0001-5366-9603 title: 'Modeling complex quantum systems : Random matrices, BCS theory, and quantum lattice systems' tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: dissertation user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd year: '2025' ... --- OA_place: repository _id: '19546' abstract: - lang: eng text: "We study the sensitivity of the eigenvectors of random matrices, showing that\r\neven small perturbations make the eigenvectors almost orthogonal. More\r\nprecisely, we consider two deformed Wigner matrices $W+D_1$, $W+D_2$ and show\r\nthat their bulk eigenvectors become asymptotically orthogonal as soon as\r\n$\\mathrm{Tr}(D_1-D_2)^2\\gg 1$, or their respective energies are separated on a\r\nscale much bigger than the local eigenvalue spacing. Furthermore, we show that\r\nquadratic forms of eigenvectors of $W+D_1$, $W+D_2$ with any deterministic\r\nmatrix $A\\in\\mathbf{C}^{N\\times N}$ in a specific subspace of codimension one\r\nare of size $N^{-1/2}$. This proves a generalization of the Eigenstate\r\nThermalization Hypothesis to eigenvectors belonging to two different spectral\r\nfamilies." acknowledgement: Supported by the ERC Advanced Grant “RMTBeyond” No. 101020331. article_processing_charge: No arxiv: 1 author: - first_name: Giorgio full_name: Cipolloni, Giorgio id: 42198EFA-F248-11E8-B48F-1D18A9856A87 last_name: Cipolloni orcid: 0000-0002-4901-7992 - first_name: László full_name: Erdös, László id: 4DBD5372-F248-11E8-B48F-1D18A9856A87 last_name: Erdös orcid: 0000-0001-5366-9603 - first_name: Sven Joscha full_name: Henheik, Sven Joscha id: 31d731d7-d235-11ea-ad11-b50331c8d7fb last_name: Henheik orcid: 0000-0003-1106-327X - first_name: Oleksii full_name: Kolupaiev, Oleksii id: 149b70d4-896a-11ed-bdf8-8c63fd44ca61 last_name: Kolupaiev orcid: 0000-0003-1491-4623 citation: ama: Cipolloni G, Erdös L, Henheik SJ, Kolupaiev O. Eigenvector decorrelation for random matrices. arXiv. doi:10.48550/arXiv.2410.10718 apa: Cipolloni, G., Erdös, L., Henheik, S. J., & Kolupaiev, O. (n.d.). Eigenvector decorrelation for random matrices. arXiv. https://doi.org/10.48550/arXiv.2410.10718 chicago: Cipolloni, Giorgio, László Erdös, Sven Joscha Henheik, and Oleksii Kolupaiev. “Eigenvector Decorrelation for Random Matrices.” ArXiv, n.d. https://doi.org/10.48550/arXiv.2410.10718. ieee: G. Cipolloni, L. Erdös, S. J. Henheik, and O. Kolupaiev, “Eigenvector decorrelation for random matrices,” arXiv. . ista: Cipolloni G, Erdös L, Henheik SJ, Kolupaiev O. Eigenvector decorrelation for random matrices. arXiv, 10.48550/arXiv.2410.10718. mla: Cipolloni, Giorgio, et al. “Eigenvector Decorrelation for Random Matrices.” ArXiv, doi:10.48550/arXiv.2410.10718. short: G. Cipolloni, L. Erdös, S.J. Henheik, O. Kolupaiev, ArXiv (n.d.). corr_author: '1' date_created: 2025-04-11T08:34:49Z date_published: 2025-01-30T00:00:00Z date_updated: 2026-04-07T12:37:11Z day: '30' department: - _id: LaEr doi: 10.48550/arXiv.2410.10718 ec_funded: 1 external_id: arxiv: - '2410.10718' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.48550/arXiv.2410.10718 month: '01' oa: 1 oa_version: Preprint project: - _id: 62796744-2b32-11ec-9570-940b20777f1d call_identifier: H2020 grant_number: '101020331' name: Random matrices beyond Wigner-Dyson-Mehta publication: arXiv publication_status: draft related_material: record: - id: '19540' relation: dissertation_contains status: public status: public title: Eigenvector decorrelation for random matrices tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: preprint user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9 year: '2025' ... --- DOAJ_listed: '1' OA_place: publisher OA_type: gold _id: '19548' abstract: - lang: eng text: "We consider the BCS energy gap „.T / (essentially given by „.T / \x19 \x81.T; p\x16/,\r\nthe BCS order parameter) at all temperatures 0 \x14 T \x14 Tc up to the critical one, Tc, and show\r\nthat, in the limit of weak coupling, the ratio „.T /=Tc is given by a universal function of the relative temperature T =Tc. On the one hand, this recovers a recent result by Langmann and Triola\r\n[Phys. Rev. B 108 (2023), no. 10, article no. 104503] on three-dimensional s-wave superconductors for temperatures bounded uniformly away from Tc. On the other hand, our result lifts these\r\nrestrictions, as we consider arbitrary spatial dimensions d 2 ¹1; 2; 3º, discuss superconductors\r\nwith non-zero angular momentum (primarily in two dimensions), and treat the perhaps physically most interesting (due to the occurrence of the superconducting phase transition) regime of\r\ntemperatures close to Tc.\r\n\r\n​\r\n ." acknowledgement: "We thank Andreas Deuchert, Christian Hainzl, Edwin Langmann, Marius Lemm, Robert Seiringer, and Jan Philip Solovej for helpful discussions,\r\nand Edwin Langmann and Robert Seiringer for valuable comments on an earlier version of the manuscript.\r\nFunding. Joscha Henheik gratefully acknowledges partial financial support by the\r\nERC Advanced Grant “RMTBeyond” No. 101020331. Asbjørn Bækgaard Lauritsen\r\ngratefully acknowledges partial financial support by the Austrian Science Fund (FWF)\r\nthrough grant DOI 10.55776/I6427 (as part of the SFB/TRR 352).\r\n" article_processing_charge: No article_type: original arxiv: 1 author: - first_name: Sven Joscha full_name: Henheik, Sven Joscha id: 31d731d7-d235-11ea-ad11-b50331c8d7fb last_name: Henheik orcid: 0000-0003-1106-327X - first_name: Asbjørn Bækgaard full_name: Lauritsen, Asbjørn Bækgaard id: e1a2682f-dc8d-11ea-abe3-81da9ac728f1 last_name: Lauritsen orcid: 0000-0003-4476-2288 citation: ama: Henheik SJ, Lauritsen AB. Universal behavior of the BCS energy gap. Journal of Spectral Theory. 2025;15(1):305–352. doi:10.4171/JST/540 apa: Henheik, S. J., & Lauritsen, A. B. (2025). Universal behavior of the BCS energy gap. Journal of Spectral Theory. EMS Press. https://doi.org/10.4171/JST/540 chicago: Henheik, Sven Joscha, and Asbjørn Bækgaard Lauritsen. “Universal Behavior of the BCS Energy Gap.” Journal of Spectral Theory. EMS Press, 2025. https://doi.org/10.4171/JST/540. ieee: S. J. Henheik and A. B. Lauritsen, “Universal behavior of the BCS energy gap,” Journal of Spectral Theory, vol. 15, no. 1. EMS Press, pp. 305–352, 2025. ista: Henheik SJ, Lauritsen AB. 2025. Universal behavior of the BCS energy gap. Journal of Spectral Theory. 15(1), 305–352. mla: Henheik, Sven Joscha, and Asbjørn Bækgaard Lauritsen. “Universal Behavior of the BCS Energy Gap.” Journal of Spectral Theory, vol. 15, no. 1, EMS Press, 2025, pp. 305–352, doi:10.4171/JST/540. short: S.J. Henheik, A.B. Lauritsen, Journal of Spectral Theory 15 (2025) 305–352. corr_author: '1' date_created: 2025-04-11T09:19:28Z date_published: 2025-01-09T00:00:00Z date_updated: 2026-04-07T12:37:11Z day: '09' ddc: - '500' department: - _id: LaEr - _id: RoSe doi: 10.4171/JST/540 ec_funded: 1 external_id: arxiv: - '2312.11310' isi: - '001438931600009' file: - access_level: open_access checksum: f49e06e8dba819f7ad52a202e287ebca content_type: application/pdf creator: cchlebak date_created: 2025-04-11T09:13:31Z date_updated: 2025-04-11T09:13:31Z file_id: '19549' file_name: Henheik_JSpectralTheory_2025.pdf file_size: 779158 relation: main_file success: 1 file_date_updated: 2025-04-11T09:13:31Z has_accepted_license: '1' intvolume: ' 15' isi: 1 issue: '1' language: - iso: eng month: '01' oa: 1 oa_version: Published Version page: 305–352 project: - _id: 62796744-2b32-11ec-9570-940b20777f1d call_identifier: H2020 grant_number: '101020331' name: Random matrices beyond Wigner-Dyson-Mehta - _id: bda63fe5-d553-11ed-ba76-a16e3d2f256b grant_number: I06427 name: Mathematical Challenges in BCS Theory of Superconductivity publication: Journal of Spectral Theory publication_identifier: eissn: - 1664-0403 publication_status: published publisher: EMS Press quality_controlled: '1' related_material: record: - id: '19540' relation: dissertation_contains status: public scopus_import: '1' status: public title: Universal behavior of the BCS energy gap tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 15 year: '2025' ... --- OA_place: repository _id: '19552' abstract: - lang: eng text: "Particle creation terms in quantum Hamiltonians are usually ultraviolet\r\ndivergent and thus mathematically ill defined. A rather novel way of solving\r\nthis problem is based on imposing so-called interior-boundary conditions on the\r\nwave function. Previous papers showed that this approach works in the\r\nnon-relativistic regime, but particle creation is mostly relevant in the\r\nrelativistic case after all. In flat relativistic space-time (that is,\r\nneglecting gravity), the approach was previously found to work only for certain\r\nsomewhat artificial cases. Here, as a way of taking gravity into account, we\r\nconsider curved space-time, specifically the super-critical\r\nReissner-Nordstr\\\"om space-time, which features a naked timelike singularity.\r\nWe find that the interior-boundary approach works fully in this setting; in\r\nparticular, we prove rigorously the existence of well-defined, self-adjoint\r\nHamiltonians with particle creation at the singularity, based on\r\ninterior-boundary conditions. We also non-rigorously analyze the asymptotic\r\nbehavior of the Bohmian trajectories and construct the corresponding Bohm-Bell\r\nprocess of particle creation, motion, and annihilation. The upshot is that in\r\nquantum physics, a naked space-time singularity need not lead to a breakdown of\r\nphysical laws, but on the contrary allows for boundary conditions governing\r\nwhat comes out of the singularity and thereby removing the ultraviolet\r\ndivergence." acknowledgement: "JH gratefully acknowledges partial financial support by the ERC Advanced\r\nGrant “RMTBeyond” No. 101020331." article_processing_charge: No arxiv: 1 author: - first_name: Sven Joscha full_name: Henheik, Sven Joscha id: 31d731d7-d235-11ea-ad11-b50331c8d7fb last_name: Henheik orcid: 0000-0003-1106-327X - first_name: Bipul full_name: Poudyal, Bipul last_name: Poudyal - first_name: Roderich full_name: Tumulka, Roderich last_name: Tumulka citation: ama: Henheik SJ, Poudyal B, Tumulka R. How a space-time singularity helps remove the ultraviolet divergence problem. arXiv. doi:10.48550/arXiv.2409.00677 apa: Henheik, S. J., Poudyal, B., & Tumulka, R. (n.d.). How a space-time singularity helps remove the ultraviolet divergence problem. arXiv. https://doi.org/10.48550/arXiv.2409.00677 chicago: Henheik, Sven Joscha, Bipul Poudyal, and Roderich Tumulka. “How a Space-Time Singularity Helps Remove the Ultraviolet Divergence Problem.” ArXiv, n.d. https://doi.org/10.48550/arXiv.2409.00677. ieee: S. J. Henheik, B. Poudyal, and R. Tumulka, “How a space-time singularity helps remove the ultraviolet divergence problem,” arXiv. . ista: Henheik SJ, Poudyal B, Tumulka R. How a space-time singularity helps remove the ultraviolet divergence problem. arXiv, 10.48550/arXiv.2409.00677. mla: Henheik, Sven Joscha, et al. “How a Space-Time Singularity Helps Remove the Ultraviolet Divergence Problem.” ArXiv, doi:10.48550/arXiv.2409.00677. short: S.J. Henheik, B. Poudyal, R. Tumulka, ArXiv (n.d.). corr_author: '1' date_created: 2025-04-11T12:07:25Z date_published: 2025-02-28T00:00:00Z date_updated: 2026-04-07T12:37:11Z day: '28' department: - _id: LaEr doi: 10.48550/arXiv.2409.00677 ec_funded: 1 external_id: arxiv: - '2409.00677' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.48550/arXiv.2409.00677 month: '02' oa: 1 oa_version: Preprint project: - _id: 62796744-2b32-11ec-9570-940b20777f1d call_identifier: H2020 grant_number: '101020331' name: Random matrices beyond Wigner-Dyson-Mehta publication: arXiv publication_status: draft related_material: record: - id: '19540' relation: dissertation_contains status: public status: public title: How a space-time singularity helps remove the ultraviolet divergence problem type: preprint user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9 year: '2025' ... --- OA_place: publisher OA_type: hybrid _id: '19554' abstract: - lang: eng text: 'In 1981, Karp and Sipser proved a law of large numbers for the matching number of a sparse Erdős–Rényi random graph, in an influential paper pioneering the so-called differential equation method for analysis of random graph processes. Strengthening this classical result, and answering a question of Aronson, Frieze and Pittel, we prove a central limit theorem in the same setting: the fluctuations in the matching number of a sparse random graph are asymptotically Gaussian. Our new contribution is to prove this central limit theorem in the subcritical and critical regimes, according to a celebrated algorithmic phase transition first observed by Karp and Sipser. Indeed, in the supercritical regime, a central limit theorem has recently been proved in the PhD thesis of Kreačić, using a stochastic generalisation of the differential equation method (comparing the so-called Karp–Sipser process to a system of stochastic differential equations). Our proof builds on these methods, and introduces new techniques to handle certain degeneracies present in the subcritical and critical cases. Curiously, our new techniques lead to a non-constructive result: we are able to characterise the fluctuations of the matching number around its mean, despite these fluctuations being much smaller than the error terms in our best estimates of the mean. We also prove a central limit theorem for the rank of the adjacency matrix of a sparse random graph.' acknowledgement: "We would like to thank Christina Goldschmidt and Eleonora Kreačić for insightful discussions and clarifications about their work in the thesis [26]. Matthew Kwan was supported by ERC Starting Grant ‘RANDSTRUCT’ No. 101076777. Ashwin Sah and Mehtaab Sawhney were supported by NSF Graduate Research Fellowship Program DGE-2141064. Ashwin Sah was supported by the PD Soros Fellowship.\r\nOpen access funding provided by Institute of Science and Technology Austria/KEMÖ." article_number: e70101 article_processing_charge: Yes (via OA deal) article_type: original arxiv: 1 author: - first_name: Margalit full_name: Glasgow, Margalit last_name: Glasgow - first_name: Matthew Alan full_name: Kwan, Matthew Alan id: 5fca0887-a1db-11eb-95d1-ca9d5e0453b3 last_name: Kwan orcid: 0000-0002-4003-7567 - first_name: Ashwin full_name: Sah, Ashwin last_name: Sah - first_name: Mehtaab full_name: Sawhney, Mehtaab last_name: Sawhney citation: ama: Glasgow M, Kwan MA, Sah A, Sawhney M. A central limit theorem for the matching number of a sparse random graph. Journal of the London Mathematical Society. 2025;111(4). doi:10.1112/jlms.70101 apa: Glasgow, M., Kwan, M. A., Sah, A., & Sawhney, M. (2025). A central limit theorem for the matching number of a sparse random graph. Journal of the London Mathematical Society. Wiley. https://doi.org/10.1112/jlms.70101 chicago: Glasgow, Margalit, Matthew Alan Kwan, Ashwin Sah, and Mehtaab Sawhney. “A Central Limit Theorem for the Matching Number of a Sparse Random Graph.” Journal of the London Mathematical Society. Wiley, 2025. https://doi.org/10.1112/jlms.70101. ieee: M. Glasgow, M. A. Kwan, A. Sah, and M. Sawhney, “A central limit theorem for the matching number of a sparse random graph,” Journal of the London Mathematical Society, vol. 111, no. 4. Wiley, 2025. ista: Glasgow M, Kwan MA, Sah A, Sawhney M. 2025. A central limit theorem for the matching number of a sparse random graph. Journal of the London Mathematical Society. 111(4), e70101. mla: Glasgow, Margalit, et al. “A Central Limit Theorem for the Matching Number of a Sparse Random Graph.” Journal of the London Mathematical Society, vol. 111, no. 4, e70101, Wiley, 2025, doi:10.1112/jlms.70101. short: M. Glasgow, M.A. Kwan, A. Sah, M. Sawhney, Journal of the London Mathematical Society 111 (2025). corr_author: '1' date_created: 2025-04-13T22:01:19Z date_published: 2025-04-01T00:00:00Z date_updated: 2025-09-30T11:35:55Z day: '01' ddc: - '510' department: - _id: MaKw doi: 10.1112/jlms.70101 external_id: arxiv: - '2402.05851' isi: - '001473087200024' file: - access_level: open_access checksum: 69ce9feaf64e776b99f3afd1041b1b11 content_type: application/pdf creator: dernst date_created: 2025-04-15T13:18:43Z date_updated: 2025-04-15T13:18:43Z file_id: '19564' file_name: 2025_JourLondMathSoc_Glasgow.pdf file_size: 392208 relation: main_file success: 1 file_date_updated: 2025-04-15T13:18:43Z has_accepted_license: '1' intvolume: ' 111' isi: 1 issue: '4' language: - iso: eng license: https://creativecommons.org/licenses/by-nc/4.0/ month: '04' oa: 1 oa_version: Published Version project: - _id: bd95085b-d553-11ed-ba76-e55d3349be45 grant_number: '101076777' name: Randomness and structure in combinatorics publication: Journal of the London Mathematical Society publication_identifier: eissn: - 1469-7750 issn: - 0024-6107 publication_status: published publisher: Wiley quality_controlled: '1' scopus_import: '1' status: public title: A central limit theorem for the matching number of a sparse random graph tmp: image: /images/cc_by_nc.png legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) short: CC BY-NC (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 111 year: '2025' ... --- OA_place: publisher OA_type: hybrid PlanS_conform: '1' _id: '19555' abstract: - lang: eng text: The charged arginine side chain is unique in determining many innate properties of proteins, contributing to stability and interaction surfaces, and directing allosteric regulation and enzymatic catalysis. NMR experiments can be used to reveal these processes at the molecular level, but it often requires selective insertion of carbon-13, nitrogen-15, and deuterium at defined atomic positions. We introduce a method to endow arginine residues with defined isotope patterns, combining synthetic organic chemistry and cell-based protein overexpression. The resulting proteins feature NMR active spin systems with optimized relaxation pathways leading to simplified NMR spectra with a sensitive response to changes in the chemical environment of the nuclei observed. acknowledged_ssus: - _id: NMR acknowledgement: We thank Lea Marie Becker for assistance with python scripts used to analyze the labeling efficiency, and Undina Guillerm, Rajkumar Singh, and Anna Kapitonova for help with protein production. This work was supported by the Austrian Science Fund (FWF; project number I5812-B) through a French-Austrian bi-national research project. We thank the Scientific Service Units (SSU) of Institute of Science and Technology Austria (ISTA) through resources provided by the NMR Facility, as well as the NMR center and MS center of the University of Vienna. article_number: e202500408 article_processing_charge: Yes (in subscription journal) article_type: original author: - first_name: Darja full_name: Rohden, Darja id: 81dc668a-19fa-11f0-bf31-d56534059ef3 last_name: Rohden - first_name: Giorgia full_name: Toscano, Giorgia last_name: Toscano - first_name: Paul full_name: Schanda, Paul id: 7B541462-FAF6-11E9-A490-E8DFE5697425 last_name: Schanda orcid: 0000-0002-9350-7606 - first_name: Roman J. full_name: Lichtenecker, Roman J. last_name: Lichtenecker citation: ama: Rohden D, Toscano G, Schanda P, Lichtenecker RJ. Synthesis of selectively 13C/2H/15N- labeled arginine to probe protein conformation and interaction by NMR spectroscopy. Chemistry - A European Journal. 2025;31(24). doi:10.1002/chem.202500408 apa: Rohden, D., Toscano, G., Schanda, P., & Lichtenecker, R. J. (2025). Synthesis of selectively 13C/2H/15N- labeled arginine to probe protein conformation and interaction by NMR spectroscopy. Chemistry - A European Journal. Wiley. https://doi.org/10.1002/chem.202500408 chicago: Rohden, Darja, Giorgia Toscano, Paul Schanda, and Roman J. Lichtenecker. “Synthesis of Selectively 13C/2H/15N- Labeled Arginine to Probe Protein Conformation and Interaction by NMR Spectroscopy.” Chemistry - A European Journal. Wiley, 2025. https://doi.org/10.1002/chem.202500408. ieee: D. Rohden, G. Toscano, P. Schanda, and R. J. Lichtenecker, “Synthesis of selectively 13C/2H/15N- labeled arginine to probe protein conformation and interaction by NMR spectroscopy,” Chemistry - A European Journal, vol. 31, no. 24. Wiley, 2025. ista: Rohden D, Toscano G, Schanda P, Lichtenecker RJ. 2025. Synthesis of selectively 13C/2H/15N- labeled arginine to probe protein conformation and interaction by NMR spectroscopy. Chemistry - A European Journal. 31(24), e202500408. mla: Rohden, Darja, et al. “Synthesis of Selectively 13C/2H/15N- Labeled Arginine to Probe Protein Conformation and Interaction by NMR Spectroscopy.” Chemistry - A European Journal, vol. 31, no. 24, e202500408, Wiley, 2025, doi:10.1002/chem.202500408. short: D. Rohden, G. Toscano, P. Schanda, R.J. Lichtenecker, Chemistry - A European Journal 31 (2025). corr_author: '1' date_created: 2025-04-13T22:01:19Z date_published: 2025-04-25T00:00:00Z date_updated: 2025-09-30T11:35:05Z day: '25' ddc: - '540' department: - _id: PaSc doi: 10.1002/chem.202500408 external_id: isi: - '001479486400019' pmid: - '40080421' file: - access_level: open_access checksum: e3788628644b5aac666cf079b05f8fa7 content_type: application/pdf creator: dernst date_created: 2025-08-05T12:59:24Z date_updated: 2025-08-05T12:59:24Z file_id: '20136' file_name: 2025_ChemistryEur_Rohden.pdf file_size: 2840681 relation: main_file success: 1 file_date_updated: 2025-08-05T12:59:24Z has_accepted_license: '1' intvolume: ' 31' isi: 1 issue: '24' language: - iso: eng month: '04' oa: 1 oa_version: Published Version pmid: 1 project: - _id: eb9c82eb-77a9-11ec-83b8-aadd536561cf grant_number: I05812 name: AlloSpace. The emergence and mechanisms of allostery publication: Chemistry - A European Journal publication_identifier: eissn: - 1521-3765 issn: - 0947-6539 publication_status: published publisher: Wiley quality_controlled: '1' scopus_import: '1' status: public title: Synthesis of selectively 13C/2H/15N- labeled arginine to probe protein conformation and interaction by NMR spectroscopy tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 31 year: '2025' ... --- OA_place: publisher _id: '19557' acknowledged_ssus: - _id: Bio - _id: PreCl - _id: ScienComp acknowledgement: "The work presented in this doctoral thesis was performed at the Institute of Science\r\nand Technology (ISTA) and financially supported by a European Research Council\r\n(ERC) Consolidator Grant (PR1028ERC02), by SFARI (PR1028SIM02) and by the\r\nAustrian Science Fund (FWF) to Gaia Novarino (PE1028W1232). I am very thankful\r\nto the Doctoral Program “Molecular Drug Targets” (MolTag) for offering me financial\r\nsupport to perform essential experiments during my PhD studies and to participate in\r\ninternational conferences and courses." alternative_title: - ISTA Thesis article_processing_charge: No author: - first_name: Lena A full_name: Schwarz, Lena A id: 29A8453C-F248-11E8-B48F-1D18A9856A87 last_name: Schwarz citation: ama: Schwarz LA. Mapping developmental dynamics of autism spectrum disorder mouse models at single-cell resolution. 2025. doi:10.15479/AT-ISTA-19557 apa: Schwarz, L. A. (2025). Mapping developmental dynamics of autism spectrum disorder mouse models at single-cell resolution. Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-19557 chicago: Schwarz, Lena A. “Mapping Developmental Dynamics of Autism Spectrum Disorder Mouse Models at Single-Cell Resolution.” Institute of Science and Technology Austria, 2025. https://doi.org/10.15479/AT-ISTA-19557. ieee: L. A. Schwarz, “Mapping developmental dynamics of autism spectrum disorder mouse models at single-cell resolution,” Institute of Science and Technology Austria, 2025. ista: Schwarz LA. 2025. Mapping developmental dynamics of autism spectrum disorder mouse models at single-cell resolution. Institute of Science and Technology Austria. mla: Schwarz, Lena A. Mapping Developmental Dynamics of Autism Spectrum Disorder Mouse Models at Single-Cell Resolution. Institute of Science and Technology Austria, 2025, doi:10.15479/AT-ISTA-19557. short: L.A. Schwarz, Mapping Developmental Dynamics of Autism Spectrum Disorder Mouse Models at Single-Cell Resolution, Institute of Science and Technology Austria, 2025. corr_author: '1' date_created: 2025-04-14T06:59:06Z date_published: 2025-04-14T00:00:00Z date_updated: 2026-04-14T09:07:14Z day: '14' ddc: - '570' degree_awarded: PhD department: - _id: GradSch - _id: GaNo doi: 10.15479/AT-ISTA-19557 file: - access_level: closed checksum: 50290a8604edb0a720387f01e9d59fe4 content_type: application/vnd.openxmlformats-officedocument.wordprocessingml.document creator: lschwarz date_created: 2025-04-15T08:43:36Z date_updated: 2025-04-15T08:43:36Z file_id: '19561' file_name: Schwarz_Thesis_2025_FINAL.docx file_size: 21783427 relation: source_file - access_level: closed checksum: ed028488180ac4901e018ef1c330cf01 content_type: application/pdf creator: lschwarz date_created: 2025-04-15T08:43:42Z date_updated: 2026-03-27T13:15:08Z embargo: 2026-10-15 embargo_to: open_access file_id: '19562' file_name: Schwarz_Thesis_2025_FINALpdfa.pdf file_size: 11432175 relation: main_file file_date_updated: 2026-03-27T13:15:08Z has_accepted_license: '1' language: - iso: eng month: '04' oa_version: Published Version page: '124' project: - _id: 9B91375C-BA93-11EA-9121-9846C619BF3A grant_number: '707964' name: Critical windows and reversibility of ASD associated with mutations in chromatin remodelers - _id: 34ba8964-11ca-11ed-8bc3-e15864e7e9a6 grant_number: '101044865' name: Toward an understanding of the brain interstitial system and the extracellular proteome in health and autism spectrum disorders - _id: 2548AE96-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: W1232 name: Molecular Drug Targets publication_identifier: issn: - 2663-337X publication_status: published publisher: Institute of Science and Technology Austria related_material: record: - id: '12802' relation: part_of_dissertation status: public - id: '9429' relation: part_of_dissertation status: public status: public supervisor: - first_name: Gaia full_name: Novarino, Gaia id: 3E57A680-F248-11E8-B48F-1D18A9856A87 last_name: Novarino orcid: 0000-0002-7673-7178 title: Mapping developmental dynamics of autism spectrum disorder mouse models at single-cell resolution tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: dissertation user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd year: '2025' ... --- OA_place: repository OA_type: green _id: '19565' abstract: - lang: eng text: 'Measuring distances in a multidimensional setting is a challenging problem, which appears in many fields of science and engineering. In this paper, to measure the distance between two multivariate distributions, we introduce a new measure of discrepancy which is scale invariant and which, in the case of two independent copies of the same distribution, and after normalization, coincides with the scaling invariant multidimensional version of the Gini index recently proposed in [P. Giudici, E. Raffinetti and G. Toscani, Measuring multidimensional inequality: A new proposal based on the Fourier transform, preprint (2024), arXiv:2401.14012 ]. A byproduct of the analysis is an easy-to-handle discrepancy metric, obtained by application of the theory to a pair of Gaussian multidimensional densities. The obtained metric does improve the standard metrics, based on the mean squared error, as it is scale invariant. The importance of this theoretical finding is illustrated by means of a real problem that concerns measuring the importance of Environmental, Social and Governance factors for the growth of small and medium enterprises. ' article_processing_charge: No article_type: original arxiv: 1 author: - first_name: Gennaro full_name: Auricchio, Gennaro last_name: Auricchio - first_name: Giovanni full_name: Brigati, Giovanni id: 63ff57e8-1fbb-11ee-88f2-f558ffc59cf1 last_name: Brigati - first_name: Paolo full_name: Giudici, Paolo last_name: Giudici - first_name: Giuseppe full_name: Toscani, Giuseppe last_name: Toscani citation: ama: Auricchio G, Brigati G, Giudici P, Toscani G. Multivariate Gini-type discrepancies. Mathematical Models and Methods in Applied Sciences. 2025;35(5):1267-1296. doi:10.1142/s0218202525500174 apa: Auricchio, G., Brigati, G., Giudici, P., & Toscani, G. (2025). Multivariate Gini-type discrepancies. Mathematical Models and Methods in Applied Sciences. World Scientific Publishing. https://doi.org/10.1142/s0218202525500174 chicago: Auricchio, Gennaro, Giovanni Brigati, Paolo Giudici, and Giuseppe Toscani. “Multivariate Gini-Type Discrepancies.” Mathematical Models and Methods in Applied Sciences. World Scientific Publishing, 2025. https://doi.org/10.1142/s0218202525500174. ieee: G. Auricchio, G. Brigati, P. Giudici, and G. Toscani, “Multivariate Gini-type discrepancies,” Mathematical Models and Methods in Applied Sciences, vol. 35, no. 5. World Scientific Publishing, pp. 1267–1296, 2025. ista: Auricchio G, Brigati G, Giudici P, Toscani G. 2025. Multivariate Gini-type discrepancies. Mathematical Models and Methods in Applied Sciences. 35(5), 1267–1296. mla: Auricchio, Gennaro, et al. “Multivariate Gini-Type Discrepancies.” Mathematical Models and Methods in Applied Sciences, vol. 35, no. 5, World Scientific Publishing, 2025, pp. 1267–96, doi:10.1142/s0218202525500174. short: G. Auricchio, G. Brigati, P. Giudici, G. Toscani, Mathematical Models and Methods in Applied Sciences 35 (2025) 1267–1296. date_created: 2025-04-15T13:34:00Z date_published: 2025-05-01T00:00:00Z date_updated: 2025-09-30T11:36:56Z day: '01' department: - _id: JaMa doi: 10.1142/s0218202525500174 external_id: arxiv: - '2411.01052' isi: - '001456337300001' intvolume: ' 35' isi: 1 issue: '5' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.48550/arXiv.2411.01052 month: '05' oa: 1 oa_version: Preprint page: 1267-1296 publication: Mathematical Models and Methods in Applied Sciences publication_identifier: eissn: - 1793-6314 issn: - 0218-2025 publication_status: published publisher: World Scientific Publishing quality_controlled: '1' scopus_import: '1' status: public title: Multivariate Gini-type discrepancies type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 35 year: '2025' ... --- APC_amount: 2236,02 EUR DOAJ_listed: '1' OA_place: publisher OA_type: gold _id: '19566' abstract: - lang: eng text: "Purpose: Optic nerve crush (ONC) is a model for studying optic nerve trauma. Unilateral ONC induces massive retinal ganglion cell (RGC) degeneration in the affected eye, leading to vision loss within a month. A common assumption has been that the non-injured contralateral eye is unaffected due to the minimal retino-retinal projections of the RGCs at the chiasm. Yet, recently, microglia, the brain-resident macrophages, have shown a responsive phenotype in the contralateral eye after ONC. Whether RGC loss accompanies this phenotype is still controversial.\r\n\r\nMethods: Using the available RGCode algorithm and developing our own RGC-Quant deep-learning-based tool, we quantify RGC's total number and density across the entire retina after ONC.\r\n\r\nResults: We confirm a short-term microglia response in the contralateral eye after ONC, but this did not affect the microglia number. Furthermore, we cannot confirm the previously reported RGC loss between naïve and contralateral retinas 5 weeks after ONC induction across the commonly used Cx3cr1creERT2 and C57BL6/J mouse models. Neither sex nor the direct comparison of the RGC markers Brn3a and RBPMS, with Brn3a co-labeling, on average, 89% of the RBPMS+-cells, explained this discrepancy, suggesting that the early microglia-responsive phenotype does not have immediate consequences on the RGC number.\r\n\r\nConclusions: Our results corroborate that unilateral optic nerve injury elicits a microglial response in the uninjured contralateral eye but without RGC loss. Therefore, the contralateral eye should be treated separately and not as an ONC control." acknowledged_ssus: - _id: Bio - _id: LifeSc - _id: PreCl acknowledgement: "The authors thank the Scientific Service Units (SSU) of ISTA for the provided resources, specifically the Imaging and Optics Facility (IOF), the Lab Support Facility (LSF), and the Pre-Clinical Facility (PCF) team, specifically Sonja Haslinger, Claudia Gold, and Michael Schunn, for mouse colony management and support. We thank all members of the Siegert group for constant feedback on the project and the manuscript. \r\nSupported in whole or in part by the Austrian Science Fund (FWF) [10.55776/P37131]. For open access purposes, the author has applied a CC BY public copyright license to any author-accepted manuscript version arising from this submission. " article_number: '49' article_processing_charge: Yes article_type: original author: - first_name: Florianne E full_name: Schoot Uiterkamp, Florianne E id: 3526230C-F248-11E8-B48F-1D18A9856A87 last_name: Schoot Uiterkamp - first_name: Margaret E full_name: Maes, Margaret E id: 3838F452-F248-11E8-B48F-1D18A9856A87 last_name: Maes orcid: 0000-0001-9642-1085 - first_name: Mohammad full_name: Alamalhoda, Mohammad last_name: Alamalhoda - first_name: Arsalan full_name: Firoozi, Arsalan last_name: Firoozi - first_name: Gloria full_name: Colombo, Gloria id: 3483CF6C-F248-11E8-B48F-1D18A9856A87 last_name: Colombo orcid: 0000-0001-9434-8902 - first_name: Sandra full_name: Siegert, Sandra id: 36ACD32E-F248-11E8-B48F-1D18A9856A87 last_name: Siegert orcid: 0000-0001-8635-0877 citation: ama: Miteva FE, Maes ME, Alamalhoda M, Firoozi A, Colombo G, Siegert S. Optic nerve crush does not induce retinal ganglion cell loss in the contralateral eye. Investigative Ophthalmology & Visual Science. 2025;66(3). doi:10.1167/iovs.66.3.49 apa: Miteva, F. E., Maes, M. E., Alamalhoda, M., Firoozi, A., Colombo, G., & Siegert, S. (2025). Optic nerve crush does not induce retinal ganglion cell loss in the contralateral eye. Investigative Ophthalmology & Visual Science. Association for Research in Vision and Ophthalmology. https://doi.org/10.1167/iovs.66.3.49 chicago: Miteva, Florianne E, Margaret E Maes, Mohammad Alamalhoda, Arsalan Firoozi, Gloria Colombo, and Sandra Siegert. “Optic Nerve Crush Does Not Induce Retinal Ganglion Cell Loss in the Contralateral Eye.” Investigative Ophthalmology & Visual Science. Association for Research in Vision and Ophthalmology, 2025. https://doi.org/10.1167/iovs.66.3.49. ieee: F. E. Miteva, M. E. Maes, M. Alamalhoda, A. Firoozi, G. Colombo, and S. Siegert, “Optic nerve crush does not induce retinal ganglion cell loss in the contralateral eye,” Investigative Ophthalmology & Visual Science, vol. 66, no. 3. Association for Research in Vision and Ophthalmology, 2025. ista: Miteva FE, Maes ME, Alamalhoda M, Firoozi A, Colombo G, Siegert S. 2025. Optic nerve crush does not induce retinal ganglion cell loss in the contralateral eye. Investigative Ophthalmology & Visual Science. 66(3), 49. mla: Miteva, Florianne E., et al. “Optic Nerve Crush Does Not Induce Retinal Ganglion Cell Loss in the Contralateral Eye.” Investigative Ophthalmology & Visual Science, vol. 66, no. 3, 49, Association for Research in Vision and Ophthalmology, 2025, doi:10.1167/iovs.66.3.49. short: F.E. Miteva, M.E. Maes, M. Alamalhoda, A. Firoozi, G. Colombo, S. Siegert, Investigative Ophthalmology & Visual Science 66 (2025). corr_author: '1' date_created: 2025-04-15T13:40:35Z date_published: 2025-03-01T00:00:00Z date_updated: 2026-05-20T06:37:12Z day: '01' ddc: - '570' department: - _id: SaSi doi: 10.1167/iovs.66.3.49 external_id: pmid: - '40126507' file: - access_level: open_access checksum: e8722ce5792f6c08fe1e191f7de6f147 content_type: application/pdf creator: dernst date_created: 2025-04-15T13:49:10Z date_updated: 2025-04-15T13:49:10Z file_id: '19567' file_name: 2025_IOVS_SchootUiterkamp.pdf file_size: 2721477 relation: main_file success: 1 file_date_updated: 2025-04-15T13:49:10Z has_accepted_license: '1' intvolume: ' 66' issue: '3' language: - iso: eng month: '03' oa: 1 oa_version: Published Version pmid: 1 project: - _id: 7be82147-9f16-11ee-852c-f44682d73140 grant_number: P37131 name: Dissecting the morpho-functional relationship of microglia - _id: 3AC91DDA-15DF-11EA-824D-93A3E7B544D1 call_identifier: FWF name: FWF Open Access Fund publication: Investigative Ophthalmology & Visual Science publication_identifier: issn: - 1552-5783 publication_status: published publisher: Association for Research in Vision and Ophthalmology quality_controlled: '1' related_material: link: - relation: software url: https://github.com/siegert-lab/RGC-Quant record: - id: '20467' relation: dissertation_contains status: public scopus_import: '1' status: public title: Optic nerve crush does not induce retinal ganglion cell loss in the contralateral eye tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 66 year: '2025' ... --- OA_type: closed access _id: '19585' abstract: - lang: eng text: Air quality in northern South America faces significant challenges due to insufficient high-resolution emission inventories and sparse atmospheric studies. This study addresses these gaps by developing a novel framework that integrates high-resolution nighttime light data from SDGSAT-1 and multisource remote sensing datasets with deep learning techniques to downscale emission inventories. The refined inventories are coupled with meteorological inputs into the Weather Research and Forecasting (WRF-Chem) model, enabling precise simulation of pollutant dynamics. Validated against ground measurements from Colombia's SISAIRE monitoring network, demonstrates significant improvements in spatiotemporal accuracy, particularly for particulate matter (PM) and nitrogen dioxide (NO₂) with error reductions of 22–30 % and correlation coefficients increasing from 0.68 to 0.85. These findings underscore the critical role of satellite-enhanced inventories in resolving localized emission patterns and seasonal variability, such as dry-season PM₁₀ spikes (150 % increase from wildfires). The framework provides policymakers with actionable insights to prioritize mitigation in rapidly urbanizing regions and manage transboundary pollution. By bridging data scarcity gaps, this replicable methodology offers transformative potential for global air quality management and public health protection, advocating for expanded ground monitoring networks and real-time satellite data integration in future applications. acknowledgement: This project was supported by the National Natural Science Foundation of China (Grant No. 42471425). The research findings are a component of the SDGSAT-1 Open Science Program, which is conducted by the International Research Center of Big Data for Sustainable Development Goals (CBAS). The data utilized in this study is sourced from SDGSAT-1 and provided by CBAS. Alejandro Casallas was supported by a fellowship awarded by the Abdus Salam International Centre for Theoretical Physics and also by the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034413. Ellie López-Barrera was supported by project No. IN.BG.086.24.015 from Universidad Sergio Arboleda. article_number: '114761' article_processing_charge: No article_type: original author: - first_name: Franz full_name: Antezana-Lopez, Franz last_name: Antezana-Lopez - first_name: Alejandro full_name: Casallas Garcia, Alejandro id: 92081129-2d75-11ef-a48d-b04dd7a2385a last_name: Casallas Garcia orcid: 0000-0002-1988-5035 - first_name: Guanhua full_name: Zhou, Guanhua last_name: Zhou - first_name: Kai full_name: Zhang, Kai last_name: Zhang - first_name: Guifei full_name: Jing, Guifei last_name: Jing - first_name: Aamir full_name: Ali, Aamir last_name: Ali - first_name: Ellie full_name: Lopez-Barrera, Ellie last_name: Lopez-Barrera - first_name: Luis Carlos full_name: Belalcazar, Luis Carlos last_name: Belalcazar - first_name: Nestor full_name: Rojas, Nestor last_name: Rojas - first_name: Hongzhi full_name: Jiang, Hongzhi last_name: Jiang citation: ama: Antezana-Lopez F, Casallas Garcia A, Zhou G, et al. High-resolution anthropogenic emission inventories with deep learning in northern South America. Remote Sensing of Environment. 2025;324. doi:10.1016/j.rse.2025.114761 apa: Antezana-Lopez, F., Casallas Garcia, A., Zhou, G., Zhang, K., Jing, G., Ali, A., … Jiang, H. (2025). High-resolution anthropogenic emission inventories with deep learning in northern South America. Remote Sensing of Environment. Elsevier. https://doi.org/10.1016/j.rse.2025.114761 chicago: Antezana-Lopez, Franz, Alejandro Casallas Garcia, Guanhua Zhou, Kai Zhang, Guifei Jing, Aamir Ali, Ellie Lopez-Barrera, Luis Carlos Belalcazar, Nestor Rojas, and Hongzhi Jiang. “High-Resolution Anthropogenic Emission Inventories with Deep Learning in Northern South America.” Remote Sensing of Environment. Elsevier, 2025. https://doi.org/10.1016/j.rse.2025.114761. ieee: F. Antezana-Lopez et al., “High-resolution anthropogenic emission inventories with deep learning in northern South America,” Remote Sensing of Environment, vol. 324. Elsevier, 2025. ista: Antezana-Lopez F, Casallas Garcia A, Zhou G, Zhang K, Jing G, Ali A, Lopez-Barrera E, Belalcazar LC, Rojas N, Jiang H. 2025. High-resolution anthropogenic emission inventories with deep learning in northern South America. Remote Sensing of Environment. 324, 114761. mla: Antezana-Lopez, Franz, et al. “High-Resolution Anthropogenic Emission Inventories with Deep Learning in Northern South America.” Remote Sensing of Environment, vol. 324, 114761, Elsevier, 2025, doi:10.1016/j.rse.2025.114761. short: F. Antezana-Lopez, A. Casallas Garcia, G. Zhou, K. Zhang, G. Jing, A. Ali, E. Lopez-Barrera, L.C. Belalcazar, N. Rojas, H. Jiang, Remote Sensing of Environment 324 (2025). date_created: 2025-04-17T09:04:17Z date_published: 2025-07-01T00:00:00Z date_updated: 2025-12-30T08:15:35Z day: '01' ddc: - '550' department: - _id: CaMu doi: 10.1016/j.rse.2025.114761 ec_funded: 1 external_id: isi: - '001475174300001' has_accepted_license: '1' intvolume: ' 324' isi: 1 language: - iso: eng month: '07' oa_version: None project: - _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c call_identifier: H2020 grant_number: '101034413' name: 'IST-BRIDGE: International postdoctoral program' publication: Remote Sensing of Environment publication_identifier: eissn: - 1879-0704 issn: - 0034-4257 publication_status: published publisher: Elsevier quality_controlled: '1' scopus_import: '1' status: public title: High-resolution anthropogenic emission inventories with deep learning in northern South America type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 324 year: '2025' ... --- APC_amount: 3948 EUR DOAJ_listed: '1' OA_place: publisher OA_type: gold PlanS_conform: '1' _id: '19593' abstract: - lang: eng text: Prenatal immune challenges pose significant risks to human embryonic brain and eye development. However, our knowledge about the safe usage of anti-inflammatory drugs during pregnancy is still limited. While human induced pluripotent stem cells (hIPSC)-derived brain organoid models have started to explore functional consequences upon viral stimulation, these models commonly lack microglia, which are susceptible to and promote inflammation. Furthermore, microglia are actively involved in neuronal development. Here, we generate hIPSC-derived microglia precursor cells and assemble them into retinal organoids. Once the outer plexiform layer forms, these hIPSC-derived microglia (iMG) fully integrate into the retinal organoids. Since the ganglion cell survival declines by this time in 3D-retinal organoids, we adapted the model into 2D and identify that the improved ganglion cell number significantly decreases only with iMG presence. In parallel, we applied the immunostimulant POLY(I:C) to mimic a fetal viral infection. While POLY(I:C) exposure alters the iMG phenotype, it does not hinder their interaction with ganglion cells. Furthermore, iMG significantly enhance the supernatant’s inflammatory secretome and increase retinal cell proliferation. Simultaneous exposure with the non-steroidal anti-inflammatory drug (NSAID) ibuprofen dampens POLY(I:C)-mediated changes of the iMG phenotype and ameliorates cell proliferation. Remarkably, while POLY(I:C) disrupts neuronal calcium dynamics independent of iMG, ibuprofen rescues this effect only if iMG are present. Mechanistically, ibuprofen targets the enzymes cyclooxygenase 1 and 2 (COX1/PTGS1 and COX2/PTGS2) simultaneously, from which iMG mainly express COX1. Selective COX1 blockage fails to restore the calcium peak amplitude upon POLY(I:C) stimulation, suggesting ibuprofen’s beneficial effect depends on the presence and interplay of COX1 and COX2. These findings underscore the importance of microglia in the context of prenatal immune challenges and provide insight into the mechanisms by which ibuprofen exerts its protective effects during embryonic development. acknowledged_ssus: - _id: LifeSc - _id: Bio acknowledgement: We thank the scientific service units at ISTA, specifically the Lab Support Facility (LSF), the Molecular Biology Services/Virus Services Team, specifically Flavia Gama Gomes Leite and Mark Andrew Smyth, for the virus production, and the Imaging and Optics Facility (IOF). We thank all members of the Siegert group and Marco Benevento for their constant feedback on the project and comments on the manuscript. A special thanks to Rouven Schulz for input on statistical analysis and sharing R-scripts, Gloria Colombo for the introduction to cell sorting, Negar Vehdani and Florianne Schoot Uiterkamp for their support in cell culture. This research was supported by the Gesellschaft für Forschungsförderung Niederösterreich (grant No. Sc19-017 to V.H.). article_number: '98' article_processing_charge: Yes article_type: original author: - first_name: Verena full_name: Hübschmann, Verena id: 32B7C918-F248-11E8-B48F-1D18A9856A87 last_name: Hübschmann - first_name: Medina full_name: Korkut, Medina id: 4B51CE74-F248-11E8-B48F-1D18A9856A87 last_name: Korkut orcid: 0000-0003-4309-2251 - first_name: Alessandro full_name: Venturino, Alessandro id: 41CB84B2-F248-11E8-B48F-1D18A9856A87 last_name: Venturino orcid: 0000-0003-2356-9403 - first_name: Juan Pablo full_name: Maya-Arteaga, Juan Pablo id: c815d433-1f5d-11f0-a875-dad18b1e5924 last_name: Maya-Arteaga - first_name: Sandra full_name: Siegert, Sandra id: 36ACD32E-F248-11E8-B48F-1D18A9856A87 last_name: Siegert orcid: 0000-0001-8635-0877 citation: ama: Schmied V, Korkut M, Venturino A, Maya-Arteaga JP, Siegert S. Microglia determine an immune-challenged environment and facilitate ibuprofen action in human retinal organoids. Journal of Neuroinflammation. 2025;22(1). doi:10.1186/s12974-025-03366-x apa: Schmied, V., Korkut, M., Venturino, A., Maya-Arteaga, J. P., & Siegert, S. (2025). Microglia determine an immune-challenged environment and facilitate ibuprofen action in human retinal organoids. Journal of Neuroinflammation. Springer Nature. https://doi.org/10.1186/s12974-025-03366-x chicago: Schmied, Verena, Medina Korkut, Alessandro Venturino, Juan Pablo Maya-Arteaga, and Sandra Siegert. “Microglia Determine an Immune-Challenged Environment and Facilitate Ibuprofen Action in Human Retinal Organoids.” Journal of Neuroinflammation. Springer Nature, 2025. https://doi.org/10.1186/s12974-025-03366-x. ieee: V. Schmied, M. Korkut, A. Venturino, J. P. Maya-Arteaga, and S. Siegert, “Microglia determine an immune-challenged environment and facilitate ibuprofen action in human retinal organoids,” Journal of Neuroinflammation, vol. 22, no. 1. Springer Nature, 2025. ista: Schmied V, Korkut M, Venturino A, Maya-Arteaga JP, Siegert S. 2025. Microglia determine an immune-challenged environment and facilitate ibuprofen action in human retinal organoids. Journal of Neuroinflammation. 22(1), 98. mla: Schmied, Verena, et al. “Microglia Determine an Immune-Challenged Environment and Facilitate Ibuprofen Action in Human Retinal Organoids.” Journal of Neuroinflammation, vol. 22, no. 1, 98, Springer Nature, 2025, doi:10.1186/s12974-025-03366-x. short: V. Schmied, M. Korkut, A. Venturino, J.P. Maya-Arteaga, S. Siegert, Journal of Neuroinflammation 22 (2025). corr_author: '1' date_created: 2025-04-20T22:01:28Z date_published: 2025-04-03T00:00:00Z date_updated: 2026-05-06T12:49:37Z day: '03' ddc: - '570' department: - _id: SaSi doi: 10.1186/s12974-025-03366-x external_id: isi: - '001459311800002' pmid: - '40181459' file: - access_level: open_access checksum: dcc355c21ab713e45fda5c61b5fa5299 content_type: application/pdf creator: dernst date_created: 2025-04-22T09:46:27Z date_updated: 2025-04-22T09:46:27Z file_id: '19607' file_name: 2025_JourNeuroinflammation_Schmied.pdf file_size: 4482167 relation: main_file success: 1 file_date_updated: 2025-04-22T09:46:27Z has_accepted_license: '1' intvolume: ' 22' isi: 1 issue: '1' language: - iso: eng month: '04' oa: 1 oa_version: Published Version pmid: 1 project: - _id: 9B99D380-BA93-11EA-9121-9846C619BF3A grant_number: SC19-017 name: How human microglia shape developing neurons during health and inflammation - _id: B67AFEDC-15C9-11EA-A837-991A96BB2854 name: IST Austria Open Access Fund publication: Journal of Neuroinflammation publication_identifier: eissn: - 1742-2094 publication_status: published publisher: Springer Nature quality_controlled: '1' related_material: link: - description: News on ISTA website relation: press_release url: https://ista.ac.at/en/news/pink-skies/ record: - id: '20074' relation: dissertation_contains status: public scopus_import: '1' status: public title: Microglia determine an immune-challenged environment and facilitate ibuprofen action in human retinal organoids tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 22 year: '2025' ...