--- OA_place: repository OA_type: green _id: '19565' abstract: - lang: eng text: 'Measuring distances in a multidimensional setting is a challenging problem, which appears in many fields of science and engineering. In this paper, to measure the distance between two multivariate distributions, we introduce a new measure of discrepancy which is scale invariant and which, in the case of two independent copies of the same distribution, and after normalization, coincides with the scaling invariant multidimensional version of the Gini index recently proposed in [P. Giudici, E. Raffinetti and G. Toscani, Measuring multidimensional inequality: A new proposal based on the Fourier transform, preprint (2024), arXiv:2401.14012 ]. A byproduct of the analysis is an easy-to-handle discrepancy metric, obtained by application of the theory to a pair of Gaussian multidimensional densities. The obtained metric does improve the standard metrics, based on the mean squared error, as it is scale invariant. The importance of this theoretical finding is illustrated by means of a real problem that concerns measuring the importance of Environmental, Social and Governance factors for the growth of small and medium enterprises. ' article_processing_charge: No article_type: original arxiv: 1 author: - first_name: Gennaro full_name: Auricchio, Gennaro last_name: Auricchio - first_name: Giovanni full_name: Brigati, Giovanni id: 63ff57e8-1fbb-11ee-88f2-f558ffc59cf1 last_name: Brigati - first_name: Paolo full_name: Giudici, Paolo last_name: Giudici - first_name: Giuseppe full_name: Toscani, Giuseppe last_name: Toscani citation: ama: Auricchio G, Brigati G, Giudici P, Toscani G. Multivariate Gini-type discrepancies. Mathematical Models and Methods in Applied Sciences. 2025;35(5):1267-1296. doi:10.1142/s0218202525500174 apa: Auricchio, G., Brigati, G., Giudici, P., & Toscani, G. (2025). Multivariate Gini-type discrepancies. Mathematical Models and Methods in Applied Sciences. World Scientific Publishing. https://doi.org/10.1142/s0218202525500174 chicago: Auricchio, Gennaro, Giovanni Brigati, Paolo Giudici, and Giuseppe Toscani. “Multivariate Gini-Type Discrepancies.” Mathematical Models and Methods in Applied Sciences. World Scientific Publishing, 2025. https://doi.org/10.1142/s0218202525500174. ieee: G. Auricchio, G. Brigati, P. Giudici, and G. Toscani, “Multivariate Gini-type discrepancies,” Mathematical Models and Methods in Applied Sciences, vol. 35, no. 5. World Scientific Publishing, pp. 1267–1296, 2025. ista: Auricchio G, Brigati G, Giudici P, Toscani G. 2025. Multivariate Gini-type discrepancies. Mathematical Models and Methods in Applied Sciences. 35(5), 1267–1296. mla: Auricchio, Gennaro, et al. “Multivariate Gini-Type Discrepancies.” Mathematical Models and Methods in Applied Sciences, vol. 35, no. 5, World Scientific Publishing, 2025, pp. 1267–96, doi:10.1142/s0218202525500174. short: G. Auricchio, G. Brigati, P. Giudici, G. Toscani, Mathematical Models and Methods in Applied Sciences 35 (2025) 1267–1296. date_created: 2025-04-15T13:34:00Z date_published: 2025-05-01T00:00:00Z date_updated: 2025-09-30T11:36:56Z day: '01' department: - _id: JaMa doi: 10.1142/s0218202525500174 external_id: arxiv: - '2411.01052' isi: - '001456337300001' intvolume: ' 35' isi: 1 issue: '5' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.48550/arXiv.2411.01052 month: '05' oa: 1 oa_version: Preprint page: 1267-1296 publication: Mathematical Models and Methods in Applied Sciences publication_identifier: eissn: - 1793-6314 issn: - 0218-2025 publication_status: published publisher: World Scientific Publishing quality_controlled: '1' scopus_import: '1' status: public title: Multivariate Gini-type discrepancies type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 35 year: '2025' ... --- APC_amount: 2236,02 EUR DOAJ_listed: '1' OA_place: publisher OA_type: gold _id: '19566' abstract: - lang: eng text: "Purpose: Optic nerve crush (ONC) is a model for studying optic nerve trauma. Unilateral ONC induces massive retinal ganglion cell (RGC) degeneration in the affected eye, leading to vision loss within a month. A common assumption has been that the non-injured contralateral eye is unaffected due to the minimal retino-retinal projections of the RGCs at the chiasm. Yet, recently, microglia, the brain-resident macrophages, have shown a responsive phenotype in the contralateral eye after ONC. Whether RGC loss accompanies this phenotype is still controversial.\r\n\r\nMethods: Using the available RGCode algorithm and developing our own RGC-Quant deep-learning-based tool, we quantify RGC's total number and density across the entire retina after ONC.\r\n\r\nResults: We confirm a short-term microglia response in the contralateral eye after ONC, but this did not affect the microglia number. Furthermore, we cannot confirm the previously reported RGC loss between naïve and contralateral retinas 5 weeks after ONC induction across the commonly used Cx3cr1creERT2 and C57BL6/J mouse models. Neither sex nor the direct comparison of the RGC markers Brn3a and RBPMS, with Brn3a co-labeling, on average, 89% of the RBPMS+-cells, explained this discrepancy, suggesting that the early microglia-responsive phenotype does not have immediate consequences on the RGC number.\r\n\r\nConclusions: Our results corroborate that unilateral optic nerve injury elicits a microglial response in the uninjured contralateral eye but without RGC loss. Therefore, the contralateral eye should be treated separately and not as an ONC control." acknowledged_ssus: - _id: Bio - _id: LifeSc - _id: PreCl acknowledgement: "The authors thank the Scientific Service Units (SSU) of ISTA for the provided resources, specifically the Imaging and Optics Facility (IOF), the Lab Support Facility (LSF), and the Pre-Clinical Facility (PCF) team, specifically Sonja Haslinger, Claudia Gold, and Michael Schunn, for mouse colony management and support. We thank all members of the Siegert group for constant feedback on the project and the manuscript. \r\nSupported in whole or in part by the Austrian Science Fund (FWF) [10.55776/P37131]. For open access purposes, the author has applied a CC BY public copyright license to any author-accepted manuscript version arising from this submission. " article_number: '49' article_processing_charge: Yes article_type: original author: - first_name: Florianne E full_name: Schoot Uiterkamp, Florianne E id: 3526230C-F248-11E8-B48F-1D18A9856A87 last_name: Schoot Uiterkamp - first_name: Margaret E full_name: Maes, Margaret E id: 3838F452-F248-11E8-B48F-1D18A9856A87 last_name: Maes orcid: 0000-0001-9642-1085 - first_name: Mohammad full_name: Alamalhoda, Mohammad last_name: Alamalhoda - first_name: Arsalan full_name: Firoozi, Arsalan last_name: Firoozi - first_name: Gloria full_name: Colombo, Gloria id: 3483CF6C-F248-11E8-B48F-1D18A9856A87 last_name: Colombo orcid: 0000-0001-9434-8902 - first_name: Sandra full_name: Siegert, Sandra id: 36ACD32E-F248-11E8-B48F-1D18A9856A87 last_name: Siegert orcid: 0000-0001-8635-0877 citation: ama: Miteva FE, Maes ME, Alamalhoda M, Firoozi A, Colombo G, Siegert S. Optic nerve crush does not induce retinal ganglion cell loss in the contralateral eye. Investigative Ophthalmology & Visual Science. 2025;66(3). doi:10.1167/iovs.66.3.49 apa: Miteva, F. E., Maes, M. E., Alamalhoda, M., Firoozi, A., Colombo, G., & Siegert, S. (2025). Optic nerve crush does not induce retinal ganglion cell loss in the contralateral eye. Investigative Ophthalmology & Visual Science. Association for Research in Vision and Ophthalmology. https://doi.org/10.1167/iovs.66.3.49 chicago: Miteva, Florianne E, Margaret E Maes, Mohammad Alamalhoda, Arsalan Firoozi, Gloria Colombo, and Sandra Siegert. “Optic Nerve Crush Does Not Induce Retinal Ganglion Cell Loss in the Contralateral Eye.” Investigative Ophthalmology & Visual Science. Association for Research in Vision and Ophthalmology, 2025. https://doi.org/10.1167/iovs.66.3.49. ieee: F. E. Miteva, M. E. Maes, M. Alamalhoda, A. Firoozi, G. Colombo, and S. Siegert, “Optic nerve crush does not induce retinal ganglion cell loss in the contralateral eye,” Investigative Ophthalmology & Visual Science, vol. 66, no. 3. Association for Research in Vision and Ophthalmology, 2025. ista: Miteva FE, Maes ME, Alamalhoda M, Firoozi A, Colombo G, Siegert S. 2025. Optic nerve crush does not induce retinal ganglion cell loss in the contralateral eye. Investigative Ophthalmology & Visual Science. 66(3), 49. mla: Miteva, Florianne E., et al. “Optic Nerve Crush Does Not Induce Retinal Ganglion Cell Loss in the Contralateral Eye.” Investigative Ophthalmology & Visual Science, vol. 66, no. 3, 49, Association for Research in Vision and Ophthalmology, 2025, doi:10.1167/iovs.66.3.49. short: F.E. Miteva, M.E. Maes, M. Alamalhoda, A. Firoozi, G. Colombo, S. Siegert, Investigative Ophthalmology & Visual Science 66 (2025). corr_author: '1' date_created: 2025-04-15T13:40:35Z date_published: 2025-03-01T00:00:00Z date_updated: 2026-05-20T06:37:12Z day: '01' ddc: - '570' department: - _id: SaSi doi: 10.1167/iovs.66.3.49 external_id: pmid: - '40126507' file: - access_level: open_access checksum: e8722ce5792f6c08fe1e191f7de6f147 content_type: application/pdf creator: dernst date_created: 2025-04-15T13:49:10Z date_updated: 2025-04-15T13:49:10Z file_id: '19567' file_name: 2025_IOVS_SchootUiterkamp.pdf file_size: 2721477 relation: main_file success: 1 file_date_updated: 2025-04-15T13:49:10Z has_accepted_license: '1' intvolume: ' 66' issue: '3' language: - iso: eng license: https://creativecommons.org/licenses/by/4.0/ month: '03' oa: 1 oa_version: Published Version pmid: 1 project: - _id: 7be82147-9f16-11ee-852c-f44682d73140 grant_number: P37131 name: Dissecting the morpho-functional relationship of microglia - _id: 3AC91DDA-15DF-11EA-824D-93A3E7B544D1 call_identifier: FWF name: FWF Open Access Fund publication: Investigative Ophthalmology & Visual Science publication_identifier: issn: - 1552-5783 publication_status: published publisher: Association for Research in Vision and Ophthalmology quality_controlled: '1' related_material: link: - relation: software url: https://github.com/siegert-lab/RGC-Quant record: - id: '20467' relation: dissertation_contains status: public scopus_import: '1' status: public title: Optic nerve crush does not induce retinal ganglion cell loss in the contralateral eye tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 66 year: '2025' ... --- OA_type: closed access _id: '19585' abstract: - lang: eng text: Air quality in northern South America faces significant challenges due to insufficient high-resolution emission inventories and sparse atmospheric studies. This study addresses these gaps by developing a novel framework that integrates high-resolution nighttime light data from SDGSAT-1 and multisource remote sensing datasets with deep learning techniques to downscale emission inventories. The refined inventories are coupled with meteorological inputs into the Weather Research and Forecasting (WRF-Chem) model, enabling precise simulation of pollutant dynamics. Validated against ground measurements from Colombia's SISAIRE monitoring network, demonstrates significant improvements in spatiotemporal accuracy, particularly for particulate matter (PM) and nitrogen dioxide (NO₂) with error reductions of 22–30 % and correlation coefficients increasing from 0.68 to 0.85. These findings underscore the critical role of satellite-enhanced inventories in resolving localized emission patterns and seasonal variability, such as dry-season PM₁₀ spikes (150 % increase from wildfires). The framework provides policymakers with actionable insights to prioritize mitigation in rapidly urbanizing regions and manage transboundary pollution. By bridging data scarcity gaps, this replicable methodology offers transformative potential for global air quality management and public health protection, advocating for expanded ground monitoring networks and real-time satellite data integration in future applications. acknowledgement: This project was supported by the National Natural Science Foundation of China (Grant No. 42471425). The research findings are a component of the SDGSAT-1 Open Science Program, which is conducted by the International Research Center of Big Data for Sustainable Development Goals (CBAS). The data utilized in this study is sourced from SDGSAT-1 and provided by CBAS. Alejandro Casallas was supported by a fellowship awarded by the Abdus Salam International Centre for Theoretical Physics and also by the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034413. Ellie López-Barrera was supported by project No. IN.BG.086.24.015 from Universidad Sergio Arboleda. article_number: '114761' article_processing_charge: No article_type: original author: - first_name: Franz full_name: Antezana-Lopez, Franz last_name: Antezana-Lopez - first_name: Alejandro full_name: Casallas Garcia, Alejandro id: 92081129-2d75-11ef-a48d-b04dd7a2385a last_name: Casallas Garcia orcid: 0000-0002-1988-5035 - first_name: Guanhua full_name: Zhou, Guanhua last_name: Zhou - first_name: Kai full_name: Zhang, Kai last_name: Zhang - first_name: Guifei full_name: Jing, Guifei last_name: Jing - first_name: Aamir full_name: Ali, Aamir last_name: Ali - first_name: Ellie full_name: Lopez-Barrera, Ellie last_name: Lopez-Barrera - first_name: Luis Carlos full_name: Belalcazar, Luis Carlos last_name: Belalcazar - first_name: Nestor full_name: Rojas, Nestor last_name: Rojas - first_name: Hongzhi full_name: Jiang, Hongzhi last_name: Jiang citation: ama: Antezana-Lopez F, Casallas Garcia A, Zhou G, et al. High-resolution anthropogenic emission inventories with deep learning in northern South America. Remote Sensing of Environment. 2025;324. doi:10.1016/j.rse.2025.114761 apa: Antezana-Lopez, F., Casallas Garcia, A., Zhou, G., Zhang, K., Jing, G., Ali, A., … Jiang, H. (2025). High-resolution anthropogenic emission inventories with deep learning in northern South America. Remote Sensing of Environment. Elsevier. https://doi.org/10.1016/j.rse.2025.114761 chicago: Antezana-Lopez, Franz, Alejandro Casallas Garcia, Guanhua Zhou, Kai Zhang, Guifei Jing, Aamir Ali, Ellie Lopez-Barrera, Luis Carlos Belalcazar, Nestor Rojas, and Hongzhi Jiang. “High-Resolution Anthropogenic Emission Inventories with Deep Learning in Northern South America.” Remote Sensing of Environment. Elsevier, 2025. https://doi.org/10.1016/j.rse.2025.114761. ieee: F. Antezana-Lopez et al., “High-resolution anthropogenic emission inventories with deep learning in northern South America,” Remote Sensing of Environment, vol. 324. Elsevier, 2025. ista: Antezana-Lopez F, Casallas Garcia A, Zhou G, Zhang K, Jing G, Ali A, Lopez-Barrera E, Belalcazar LC, Rojas N, Jiang H. 2025. High-resolution anthropogenic emission inventories with deep learning in northern South America. Remote Sensing of Environment. 324, 114761. mla: Antezana-Lopez, Franz, et al. “High-Resolution Anthropogenic Emission Inventories with Deep Learning in Northern South America.” Remote Sensing of Environment, vol. 324, 114761, Elsevier, 2025, doi:10.1016/j.rse.2025.114761. short: F. Antezana-Lopez, A. Casallas Garcia, G. Zhou, K. Zhang, G. Jing, A. Ali, E. Lopez-Barrera, L.C. Belalcazar, N. Rojas, H. Jiang, Remote Sensing of Environment 324 (2025). date_created: 2025-04-17T09:04:17Z date_published: 2025-07-01T00:00:00Z date_updated: 2025-12-30T08:15:35Z day: '01' ddc: - '550' department: - _id: CaMu doi: 10.1016/j.rse.2025.114761 ec_funded: 1 external_id: isi: - '001475174300001' has_accepted_license: '1' intvolume: ' 324' isi: 1 language: - iso: eng month: '07' oa_version: None project: - _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c call_identifier: H2020 grant_number: '101034413' name: 'IST-BRIDGE: International postdoctoral program' publication: Remote Sensing of Environment publication_identifier: eissn: - 1879-0704 issn: - 0034-4257 publication_status: published publisher: Elsevier quality_controlled: '1' scopus_import: '1' status: public title: High-resolution anthropogenic emission inventories with deep learning in northern South America type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 324 year: '2025' ... --- APC_amount: 3948 EUR DOAJ_listed: '1' OA_place: publisher OA_type: gold PlanS_conform: '1' _id: '19593' abstract: - lang: eng text: Prenatal immune challenges pose significant risks to human embryonic brain and eye development. However, our knowledge about the safe usage of anti-inflammatory drugs during pregnancy is still limited. While human induced pluripotent stem cells (hIPSC)-derived brain organoid models have started to explore functional consequences upon viral stimulation, these models commonly lack microglia, which are susceptible to and promote inflammation. Furthermore, microglia are actively involved in neuronal development. Here, we generate hIPSC-derived microglia precursor cells and assemble them into retinal organoids. Once the outer plexiform layer forms, these hIPSC-derived microglia (iMG) fully integrate into the retinal organoids. Since the ganglion cell survival declines by this time in 3D-retinal organoids, we adapted the model into 2D and identify that the improved ganglion cell number significantly decreases only with iMG presence. In parallel, we applied the immunostimulant POLY(I:C) to mimic a fetal viral infection. While POLY(I:C) exposure alters the iMG phenotype, it does not hinder their interaction with ganglion cells. Furthermore, iMG significantly enhance the supernatant’s inflammatory secretome and increase retinal cell proliferation. Simultaneous exposure with the non-steroidal anti-inflammatory drug (NSAID) ibuprofen dampens POLY(I:C)-mediated changes of the iMG phenotype and ameliorates cell proliferation. Remarkably, while POLY(I:C) disrupts neuronal calcium dynamics independent of iMG, ibuprofen rescues this effect only if iMG are present. Mechanistically, ibuprofen targets the enzymes cyclooxygenase 1 and 2 (COX1/PTGS1 and COX2/PTGS2) simultaneously, from which iMG mainly express COX1. Selective COX1 blockage fails to restore the calcium peak amplitude upon POLY(I:C) stimulation, suggesting ibuprofen’s beneficial effect depends on the presence and interplay of COX1 and COX2. These findings underscore the importance of microglia in the context of prenatal immune challenges and provide insight into the mechanisms by which ibuprofen exerts its protective effects during embryonic development. acknowledged_ssus: - _id: LifeSc - _id: Bio acknowledgement: We thank the scientific service units at ISTA, specifically the Lab Support Facility (LSF), the Molecular Biology Services/Virus Services Team, specifically Flavia Gama Gomes Leite and Mark Andrew Smyth, for the virus production, and the Imaging and Optics Facility (IOF). We thank all members of the Siegert group and Marco Benevento for their constant feedback on the project and comments on the manuscript. A special thanks to Rouven Schulz for input on statistical analysis and sharing R-scripts, Gloria Colombo for the introduction to cell sorting, Negar Vehdani and Florianne Schoot Uiterkamp for their support in cell culture. This research was supported by the Gesellschaft für Forschungsförderung Niederösterreich (grant No. Sc19-017 to V.H.). article_number: '98' article_processing_charge: Yes article_type: original author: - first_name: Verena full_name: Hübschmann, Verena id: 32B7C918-F248-11E8-B48F-1D18A9856A87 last_name: Hübschmann - first_name: Medina full_name: Korkut, Medina id: 4B51CE74-F248-11E8-B48F-1D18A9856A87 last_name: Korkut orcid: 0000-0003-4309-2251 - first_name: Alessandro full_name: Venturino, Alessandro id: 41CB84B2-F248-11E8-B48F-1D18A9856A87 last_name: Venturino orcid: 0000-0003-2356-9403 - first_name: Juan Pablo full_name: Maya-Arteaga, Juan Pablo id: c815d433-1f5d-11f0-a875-dad18b1e5924 last_name: Maya-Arteaga - first_name: Sandra full_name: Siegert, Sandra id: 36ACD32E-F248-11E8-B48F-1D18A9856A87 last_name: Siegert orcid: 0000-0001-8635-0877 citation: ama: Schmied V, Korkut M, Venturino A, Maya-Arteaga JP, Siegert S. Microglia determine an immune-challenged environment and facilitate ibuprofen action in human retinal organoids. Journal of Neuroinflammation. 2025;22(1). doi:10.1186/s12974-025-03366-x apa: Schmied, V., Korkut, M., Venturino, A., Maya-Arteaga, J. P., & Siegert, S. (2025). Microglia determine an immune-challenged environment and facilitate ibuprofen action in human retinal organoids. Journal of Neuroinflammation. Springer Nature. https://doi.org/10.1186/s12974-025-03366-x chicago: Schmied, Verena, Medina Korkut, Alessandro Venturino, Juan Pablo Maya-Arteaga, and Sandra Siegert. “Microglia Determine an Immune-Challenged Environment and Facilitate Ibuprofen Action in Human Retinal Organoids.” Journal of Neuroinflammation. Springer Nature, 2025. https://doi.org/10.1186/s12974-025-03366-x. ieee: V. Schmied, M. Korkut, A. Venturino, J. P. Maya-Arteaga, and S. Siegert, “Microglia determine an immune-challenged environment and facilitate ibuprofen action in human retinal organoids,” Journal of Neuroinflammation, vol. 22, no. 1. Springer Nature, 2025. ista: Schmied V, Korkut M, Venturino A, Maya-Arteaga JP, Siegert S. 2025. Microglia determine an immune-challenged environment and facilitate ibuprofen action in human retinal organoids. Journal of Neuroinflammation. 22(1), 98. mla: Schmied, Verena, et al. “Microglia Determine an Immune-Challenged Environment and Facilitate Ibuprofen Action in Human Retinal Organoids.” Journal of Neuroinflammation, vol. 22, no. 1, 98, Springer Nature, 2025, doi:10.1186/s12974-025-03366-x. short: V. Schmied, M. Korkut, A. Venturino, J.P. Maya-Arteaga, S. Siegert, Journal of Neuroinflammation 22 (2025). corr_author: '1' date_created: 2025-04-20T22:01:28Z date_published: 2025-04-03T00:00:00Z date_updated: 2026-05-06T12:49:37Z day: '03' ddc: - '570' department: - _id: SaSi doi: 10.1186/s12974-025-03366-x external_id: isi: - '001459311800002' pmid: - '40181459' file: - access_level: open_access checksum: dcc355c21ab713e45fda5c61b5fa5299 content_type: application/pdf creator: dernst date_created: 2025-04-22T09:46:27Z date_updated: 2025-04-22T09:46:27Z file_id: '19607' file_name: 2025_JourNeuroinflammation_Schmied.pdf file_size: 4482167 relation: main_file success: 1 file_date_updated: 2025-04-22T09:46:27Z has_accepted_license: '1' intvolume: ' 22' isi: 1 issue: '1' language: - iso: eng month: '04' oa: 1 oa_version: Published Version pmid: 1 project: - _id: 9B99D380-BA93-11EA-9121-9846C619BF3A grant_number: SC19-017 name: How human microglia shape developing neurons during health and inflammation - _id: B67AFEDC-15C9-11EA-A837-991A96BB2854 name: IST Austria Open Access Fund publication: Journal of Neuroinflammation publication_identifier: eissn: - 1742-2094 publication_status: published publisher: Springer Nature quality_controlled: '1' related_material: link: - description: News on ISTA website relation: press_release url: https://ista.ac.at/en/news/pink-skies/ record: - id: '20074' relation: dissertation_contains status: public scopus_import: '1' status: public title: Microglia determine an immune-challenged environment and facilitate ibuprofen action in human retinal organoids tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 22 year: '2025' ... --- OA_type: closed access _id: '19594' abstract: - lang: eng text: In this issue of Developmental Cell, Lee et al. identify a pivotal role for glutathione (GSH) in plant regeneration, a vital biological process enabling plants to regrow tissues and organs after injury. Applying single-cell RNA sequencing (scRNA-seq) and live imaging, the authors demonstrate that GSH, released upon tissue damage, accelerates cell-cycle transitions, particularly shortening the G1 phase, thereby facilitating efficient organ regeneration. article_processing_charge: No article_type: letter_note author: - first_name: Eva full_name: Benková, Eva id: 38F4F166-F248-11E8-B48F-1D18A9856A87 last_name: Benková orcid: 0000-0002-8510-9739 citation: ama: 'Benková E. Unlocking plant regeneration: The role for glutathione. Developmental Cell. 2025;60(8):1137-1139. doi:10.1016/j.devcel.2025.03.012' apa: 'Benková, E. (2025). Unlocking plant regeneration: The role for glutathione. Developmental Cell. Elsevier. https://doi.org/10.1016/j.devcel.2025.03.012' chicago: 'Benková, Eva. “Unlocking Plant Regeneration: The Role for Glutathione.” Developmental Cell. Elsevier, 2025. https://doi.org/10.1016/j.devcel.2025.03.012.' ieee: 'E. Benková, “Unlocking plant regeneration: The role for glutathione,” Developmental Cell, vol. 60, no. 8. Elsevier, pp. 1137–1139, 2025.' ista: 'Benková E. 2025. Unlocking plant regeneration: The role for glutathione. Developmental Cell. 60(8), 1137–1139.' mla: 'Benková, Eva. “Unlocking Plant Regeneration: The Role for Glutathione.” Developmental Cell, vol. 60, no. 8, Elsevier, 2025, pp. 1137–39, doi:10.1016/j.devcel.2025.03.012.' short: E. Benková, Developmental Cell 60 (2025) 1137–1139. corr_author: '1' date_created: 2025-04-20T22:01:28Z date_published: 2025-04-21T00:00:00Z date_updated: 2025-09-30T12:07:36Z day: '21' department: - _id: EvBe doi: 10.1016/j.devcel.2025.03.012 external_id: isi: - '001477400800001' pmid: - '40262524' intvolume: ' 60' isi: 1 issue: '8' language: - iso: eng month: '04' oa_version: None page: 1137-1139 pmid: 1 publication: Developmental Cell publication_identifier: eissn: - 1878-1551 issn: - 1534-5807 publication_status: published publisher: Elsevier quality_controlled: '1' scopus_import: '1' status: public title: 'Unlocking plant regeneration: The role for glutathione' type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 60 year: '2025' ... --- OA_place: publisher OA_type: hybrid _id: '19595' abstract: - lang: eng text: We investigate the locality of magnetic response in polycyclic aromatic molecules using a novel deep-learning approach. Our method employs graph neural networks (GNNs) with a graph-of-rings representation to predict nucleus independent chemical shifts (NICS) in the space around the molecule. We train a series of models, each time reducing the size of the largest molecules used in training. The accuracy of prediction remains high (MAE < 0.5 ppm), even when training the model only on molecules with up to four rings, thus providing strong evidence for the locality of magnetic response. To overcome the known problem of generalization of GNNs, we implement a k-hop expansion strategy and succeed in achieving accurate predictions for molecules with up to 15 rings (almost 4 times the size of the largest training example). Our findings have implications for understanding the magnetic response in complex molecules and demonstrate a promising approach to overcoming GNN scalability limitations. Furthermore, the trained models enable rapid characterization, without the need for more expensive DFT calculations. acknowledgement: The authors express their gratitude to Professor Dr. Peter Chen for his continued support. The authors acknowledge the Branco Weiss Fellowship for supporting this research as part of a Society in Science grant and the Israel Science Foundation for financial support (Grant No. 1745/23 to R.G.-P.). R.G.-P. is a Branco Weiss Fellow, a Horev Fellow, and an Alon Scholarship recipient. A.M.B. was supported by the ERC StG EARS and the Israeli Science Foundation. article_number: '144101' article_processing_charge: Yes (in subscription journal) article_type: original author: - first_name: Yair full_name: Davidson, Yair last_name: Davidson - first_name: Aviad full_name: Philipp, Aviad last_name: Philipp - first_name: Sabyasachi full_name: Chakraborty, Sabyasachi last_name: Chakraborty - first_name: Alexander full_name: Bronstein, Alexander id: 58f3726e-7cba-11ef-ad8b-e6e8cb3904e6 last_name: Bronstein orcid: 0000-0001-9699-8730 - first_name: Renana full_name: Gershoni-Poranne, Renana last_name: Gershoni-Poranne citation: ama: Davidson Y, Philipp A, Chakraborty S, Bronstein AM, Gershoni-Poranne R. How local is “local”? Deep learning reveals locality of the induced magnetic field of polycyclic aromatic hydrocarbons. Journal of Chemical Physics. 2025;162(14). doi:10.1063/5.0257558 apa: Davidson, Y., Philipp, A., Chakraborty, S., Bronstein, A. M., & Gershoni-Poranne, R. (2025). How local is “local”? Deep learning reveals locality of the induced magnetic field of polycyclic aromatic hydrocarbons. Journal of Chemical Physics. AIP Publishing. https://doi.org/10.1063/5.0257558 chicago: Davidson, Yair, Aviad Philipp, Sabyasachi Chakraborty, Alex M. Bronstein, and Renana Gershoni-Poranne. “How Local Is ‘Local’? Deep Learning Reveals Locality of the Induced Magnetic Field of Polycyclic Aromatic Hydrocarbons.” Journal of Chemical Physics. AIP Publishing, 2025. https://doi.org/10.1063/5.0257558. ieee: Y. Davidson, A. Philipp, S. Chakraborty, A. M. Bronstein, and R. Gershoni-Poranne, “How local is ‘local’? Deep learning reveals locality of the induced magnetic field of polycyclic aromatic hydrocarbons,” Journal of Chemical Physics, vol. 162, no. 14. AIP Publishing, 2025. ista: Davidson Y, Philipp A, Chakraborty S, Bronstein AM, Gershoni-Poranne R. 2025. How local is “local”? Deep learning reveals locality of the induced magnetic field of polycyclic aromatic hydrocarbons. Journal of Chemical Physics. 162(14), 144101. mla: Davidson, Yair, et al. “How Local Is ‘Local’? Deep Learning Reveals Locality of the Induced Magnetic Field of Polycyclic Aromatic Hydrocarbons.” Journal of Chemical Physics, vol. 162, no. 14, 144101, AIP Publishing, 2025, doi:10.1063/5.0257558. short: Y. Davidson, A. Philipp, S. Chakraborty, A.M. Bronstein, R. Gershoni-Poranne, Journal of Chemical Physics 162 (2025). corr_author: '1' date_created: 2025-04-20T22:01:28Z date_published: 2025-04-14T00:00:00Z date_updated: 2025-09-30T12:06:51Z day: '14' ddc: - '000' department: - _id: AlBr doi: 10.1063/5.0257558 external_id: isi: - '001466311300030' pmid: - '40197568' file: - access_level: open_access checksum: 20a31a4c506b52de863bab7d3ff989ef content_type: application/pdf creator: dernst date_created: 2025-04-22T09:27:43Z date_updated: 2025-04-22T09:27:43Z file_id: '19606' file_name: 2025_JourChemicalPhysics_Davidson.pdf file_size: 7812182 relation: main_file success: 1 file_date_updated: 2025-04-22T09:27:43Z has_accepted_license: '1' intvolume: ' 162' isi: 1 issue: '14' language: - iso: eng license: https://creativecommons.org/licenses/by-nc/4.0/ month: '04' oa: 1 oa_version: Published Version pmid: 1 project: - _id: 92f4a086-16d5-11f0-9cad-c929f5c58b0c grant_number: '863839' name: Acoustics-based drone navigation and interaction publication: Journal of Chemical Physics publication_identifier: eissn: - 1089-7690 issn: - 0021-9606 publication_status: published publisher: AIP Publishing quality_controlled: '1' related_material: link: - relation: software url: https://gitlab.com/porannegroup/magnetic_locality scopus_import: '1' status: public title: How local is “local”? Deep learning reveals locality of the induced magnetic field of polycyclic aromatic hydrocarbons tmp: image: /images/cc_by_nc.png legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) short: CC BY-NC (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 162 year: '2025' ... --- DOAJ_listed: '1' OA_place: publisher OA_type: gold _id: '19596' abstract: - lang: eng text: "We report the spectroscopic discovery of a massive quiescent galaxy at zspec = 7.29 ± 0.01, just ∼700 Myr after the big bang. RUBIES-UDS-QG-z7 was selected from public JWST/NIRCam and MIRI imaging from the PRIMER survey and observed with JWST/NIRSpec as part of RUBIES. The NIRSpec/PRISM spectrum reveals one of the strongest Balmer breaks observed thus far at z > 6, with no emission lines but tentative Balmer and Ca absorption features, as well as a Lyman break. Simultaneous modeling of the NIRSpec/PRISM spectrum and NIRCam and MIRI photometry (spanning 0.9–18 μm) shows that the galaxy formed a stellar mass of\r\n(math. formular) before z ∼ 8 and ceased forming stars 50–100 Myr prior to the time of observation, resulting in log (sSFR/Gyr- 1) < -1 . We measure a small physical size of (math formular) , which implies a high stellarmass surface density within the effective radius of (math formular) comparable to the highest densities measured in quiescent galaxies at z ∼ 2–5. The 3D stellar-mass density profile of RUBIES-UDS-QG-z7 is remarkably similar to the central densities of local massive ellipticals, suggesting that at least some of their cores may have already been in place at z > 7. The discovery of RUBIES-UDS-QG-z7 has strong implications for galaxy formation models: the estimated number density of quiescent galaxies at z ∼ 7 is >100 × larger than predicted from any model to date, indicating that quiescent galaxies have formed earlier than previously expected. " acknowledgement: "We thank the PRIMER team for making their imaging data publicly available immediately. This work is based on observations made with the NASA/ESA/CSA James Webb Space Telescope. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with program #4233. Support for program #4233 was provided by NASA through a grant from the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127. This research was supported by the International Space Science Institute (ISSI) in Bern, through ISSI International Team project #562. The Cosmic Dawn Center is funded by the Danish National Research Foundation (DNRF140). This work has received funding from the Swiss State Secretariat for Education, Research and Innovation (SERI), under contract number MB22.00072, as well as from the Swiss National Science Foundation (SNSF), through project grant 200020_207349. Support for this work was provided by The Brinson Foundation through a Brinson Prize Fellowship grant. Support for this work for R.P.N. was provided by NASA through the NASA Hubble Fellowship grant HST-HF2-51515.001-A, awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Incorporated, under NASA contract NAS5-26555. T.B.M. was supported by a CIERA fellowship.\r\nAll software packages used in this work are publicly available on Github: grizli, msafit, msaexp, Prospector, and sedpy. We acknowledge: astropy (Astropy Collaboration et al. 2013, 2018, 2022), matplotlib (J. D. Hunter 2007), numpy (C. R. Harris et al. 2020), scipy (P. Virtanen et al. 2020), lmfit (M. Newville et al. 2024), eMPT (N. Bonaventura et al. 2023), the jwst pipeline (H. Bushouse et al. 2024), msaexp (G. Brammer 2024a), and grizli (G. Brammer 2024b),." article_number: '11' article_processing_charge: Yes article_type: original arxiv: 1 author: - first_name: Andrea full_name: Weibel, Andrea last_name: Weibel - first_name: Anna full_name: De Graaff, Anna last_name: De Graaff - first_name: David J. full_name: Setton, David J. last_name: Setton - first_name: Tim B. full_name: Miller, Tim B. last_name: Miller - first_name: Pascal A. full_name: Oesch, Pascal A. last_name: Oesch - first_name: Gabriel full_name: Brammer, Gabriel last_name: Brammer - first_name: Claudia D.P. full_name: Lagos, Claudia D.P. last_name: Lagos - first_name: Katherine E. full_name: Whitaker, Katherine E. last_name: Whitaker - first_name: Christina C. full_name: Williams, Christina C. last_name: Williams - first_name: Josephine F.W. full_name: Baggen, Josephine F.W. last_name: Baggen - first_name: Rachel full_name: Bezanson, Rachel last_name: Bezanson - first_name: Leindert A. full_name: Boogaard, Leindert A. last_name: Boogaard - first_name: Nikko J. full_name: Cleri, Nikko J. last_name: Cleri - first_name: Jenny E. full_name: Greene, Jenny E. last_name: Greene - first_name: Michaela full_name: Hirschmann, Michaela last_name: Hirschmann - first_name: Raphael E. full_name: Hviding, Raphael E. last_name: Hviding - first_name: Adarsh full_name: Kuruvanthodi, Adarsh last_name: Kuruvanthodi - first_name: Ivo full_name: Labbé, Ivo last_name: Labbé - first_name: Joel full_name: Leja, Joel last_name: Leja - first_name: Michael V. full_name: Maseda, Michael V. last_name: Maseda - first_name: Jorryt J full_name: Matthee, Jorryt J id: 7439a258-f3c0-11ec-9501-9df22fe06720 last_name: Matthee orcid: 0000-0003-2871-127X - first_name: Ian full_name: Mcconachie, Ian last_name: Mcconachie - first_name: Rohan P. full_name: Naidu, Rohan P. last_name: Naidu - first_name: Guido full_name: Roberts-Borsani, Guido last_name: Roberts-Borsani - first_name: Daniel full_name: Schaerer, Daniel last_name: Schaerer - first_name: Katherine A. full_name: Suess, Katherine A. last_name: Suess - first_name: Francesco full_name: Valentino, Francesco last_name: Valentino - first_name: Pieter full_name: Van Dokkum, Pieter last_name: Van Dokkum - first_name: Bingjie full_name: Wang, Bingjie last_name: Wang citation: ama: Weibel A, De Graaff A, Setton DJ, et al. RUBIES reveals a massive quiescent galaxy at z = 7.3. The Astrophysical Journal. 2025;983(1). doi:10.3847/1538-4357/adab7a apa: Weibel, A., De Graaff, A., Setton, D. J., Miller, T. B., Oesch, P. A., Brammer, G., … Wang, B. (2025). RUBIES reveals a massive quiescent galaxy at z = 7.3. The Astrophysical Journal. IOP Publishing. https://doi.org/10.3847/1538-4357/adab7a chicago: Weibel, Andrea, Anna De Graaff, David J. Setton, Tim B. Miller, Pascal A. Oesch, Gabriel Brammer, Claudia D.P. Lagos, et al. “RUBIES Reveals a Massive Quiescent Galaxy at z = 7.3.” The Astrophysical Journal. IOP Publishing, 2025. https://doi.org/10.3847/1538-4357/adab7a. ieee: A. Weibel et al., “RUBIES reveals a massive quiescent galaxy at z = 7.3,” The Astrophysical Journal, vol. 983, no. 1. IOP Publishing, 2025. ista: Weibel A, De Graaff A, Setton DJ, Miller TB, Oesch PA, Brammer G, Lagos CDP, Whitaker KE, Williams CC, Baggen JFW, Bezanson R, Boogaard LA, Cleri NJ, Greene JE, Hirschmann M, Hviding RE, Kuruvanthodi A, Labbé I, Leja J, Maseda MV, Matthee JJ, Mcconachie I, Naidu RP, Roberts-Borsani G, Schaerer D, Suess KA, Valentino F, Van Dokkum P, Wang B. 2025. RUBIES reveals a massive quiescent galaxy at z = 7.3. The Astrophysical Journal. 983(1), 11. mla: Weibel, Andrea, et al. “RUBIES Reveals a Massive Quiescent Galaxy at z = 7.3.” The Astrophysical Journal, vol. 983, no. 1, 11, IOP Publishing, 2025, doi:10.3847/1538-4357/adab7a. short: A. Weibel, A. De Graaff, D.J. Setton, T.B. Miller, P.A. Oesch, G. Brammer, C.D.P. Lagos, K.E. Whitaker, C.C. Williams, J.F.W. Baggen, R. Bezanson, L.A. Boogaard, N.J. Cleri, J.E. Greene, M. Hirschmann, R.E. Hviding, A. Kuruvanthodi, I. Labbé, J. Leja, M.V. Maseda, J.J. Matthee, I. Mcconachie, R.P. Naidu, G. Roberts-Borsani, D. Schaerer, K.A. Suess, F. Valentino, P. Van Dokkum, B. Wang, The Astrophysical Journal 983 (2025). date_created: 2025-04-20T22:01:28Z date_published: 2025-04-10T00:00:00Z date_updated: 2026-02-16T12:42:28Z day: '10' ddc: - '520' department: - _id: JoMa doi: 10.3847/1538-4357/adab7a external_id: arxiv: - '2409.03829' isi: - '001457334900001' file: - access_level: open_access checksum: a1132e0b18bb643f9a32674c6694375a content_type: application/pdf creator: dernst date_created: 2025-04-22T09:08:17Z date_updated: 2025-04-22T09:08:17Z file_id: '19605' file_name: 2025_AstrophysicalJour_Weibel.pdf file_size: 1964589 relation: main_file success: 1 file_date_updated: 2025-04-22T09:08:17Z has_accepted_license: '1' intvolume: ' 983' isi: 1 issue: '1' language: - iso: eng month: '04' oa: 1 oa_version: Published Version publication: The Astrophysical Journal publication_identifier: eissn: - 1538-4357 issn: - 0004-637X publication_status: published publisher: IOP Publishing quality_controlled: '1' scopus_import: '1' status: public title: RUBIES reveals a massive quiescent galaxy at z = 7.3 tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 983 year: '2025' ... --- APC_amount: 3036,92 EUR DOAJ_listed: '1' OA_place: publisher OA_type: hybrid PlanS_conform: '1' _id: '19597' abstract: - lang: eng text: Superconductor–semiconductor hybrid systems play a crucial role in realizing nanoscale quantum devices, including hybrid qubits, Majorana bound states, and Kitaev chains. For such hybrid devices, subgap states play a prominent role in their operation. In this paper, we study these subgap states via Coulomb and tunneling spectroscopy through a superconducting island defined in a semiconductor nanowire fully coated by a superconductor. We systematically explore regimes ranging from an almost decoupled island to the open configuration. In the weak-coupling regime, the experimental observations are very similar in the absence of a magnetic field and when one flux quantum pierces the superconducting shell. Conversely, in the strong-coupling regime, significant distinctions emerge between the two cases. We attribute this distinct behavior to the existence of subgap states at one flux quantum, which become observable only for sufficiently strong coupling to the leads. We support our interpretation using a simple model to describe transport through the island. Our study highlights the importance of studying a broad range of tunnel couplings for understanding the rich physics of hybrid devices. acknowledged_ssus: - _id: M-Shop - _id: NanoFab acknowledgement: This research was supported by the Scientific Service Units of ISTA, through resources provided by the MIBA Machine Shop and the Nanofabrication facility. This research and related results were made possible with the support of the FWF Project with DOI10.55776/F86. We acknowledge support from the European Research Council under the European Unions Horizon 2020 research and innovation programme under Grant Agreement No. 856526, the Swedish Research Council under Grant Agreement No. 2020-03412, the Spanish Comunidad de Madrid (CM) “Talento Program” (Project No. 2022-T1/IND-24070), the Spanish Ministry of Science, innovation, and Universities through Grant PID2022-140552NA-I00 and NanoLund. article_number: '023022' article_processing_charge: Yes article_type: original author: - first_name: Marco full_name: Valentini, Marco id: C0BB2FAC-D767-11E9-B658-BC13E6697425 last_name: Valentini - first_name: Rubén Seoane full_name: Souto, Rubén Seoane last_name: Souto - first_name: Maksim full_name: Borovkov, Maksim id: 1fd0975f-8b61-11ed-b69e-d149334f28c5 last_name: Borovkov - first_name: Peter full_name: Krogstrup, Peter last_name: Krogstrup - first_name: Yigal full_name: Meir, Yigal last_name: Meir - first_name: Martin full_name: Leijnse, Martin last_name: Leijnse - first_name: Jeroen full_name: Danon, Jeroen last_name: Danon - first_name: Georgios full_name: Katsaros, Georgios id: 38DB5788-F248-11E8-B48F-1D18A9856A87 last_name: Katsaros orcid: 0000-0001-8342-202X citation: ama: 'Valentini M, Souto RS, Borovkov M, et al. Subgap transport in superconductor-semiconductor hybrid islands: Weak and strong coupling regimes. Physical Review Research. 2025;7(2). doi:10.1103/PhysRevResearch.7.023022' apa: 'Valentini, M., Souto, R. S., Borovkov, M., Krogstrup, P., Meir, Y., Leijnse, M., … Katsaros, G. (2025). Subgap transport in superconductor-semiconductor hybrid islands: Weak and strong coupling regimes. Physical Review Research. American Physical Society. https://doi.org/10.1103/PhysRevResearch.7.023022' chicago: 'Valentini, Marco, Rubén Seoane Souto, Maksim Borovkov, Peter Krogstrup, Yigal Meir, Martin Leijnse, Jeroen Danon, and Georgios Katsaros. “Subgap Transport in Superconductor-Semiconductor Hybrid Islands: Weak and Strong Coupling Regimes.” Physical Review Research. American Physical Society, 2025. https://doi.org/10.1103/PhysRevResearch.7.023022.' ieee: 'M. Valentini et al., “Subgap transport in superconductor-semiconductor hybrid islands: Weak and strong coupling regimes,” Physical Review Research, vol. 7, no. 2. American Physical Society, 2025.' ista: 'Valentini M, Souto RS, Borovkov M, Krogstrup P, Meir Y, Leijnse M, Danon J, Katsaros G. 2025. Subgap transport in superconductor-semiconductor hybrid islands: Weak and strong coupling regimes. Physical Review Research. 7(2), 023022.' mla: 'Valentini, Marco, et al. “Subgap Transport in Superconductor-Semiconductor Hybrid Islands: Weak and Strong Coupling Regimes.” Physical Review Research, vol. 7, no. 2, 023022, American Physical Society, 2025, doi:10.1103/PhysRevResearch.7.023022.' short: M. Valentini, R.S. Souto, M. Borovkov, P. Krogstrup, Y. Meir, M. Leijnse, J. Danon, G. Katsaros, Physical Review Research 7 (2025). corr_author: '1' date_created: 2025-04-20T22:01:28Z date_published: 2025-04-01T00:00:00Z date_updated: 2026-06-11T09:13:12Z day: '01' ddc: - '530' department: - _id: GeKa doi: 10.1103/PhysRevResearch.7.023022 file: - access_level: open_access checksum: 535351066e9c900340ef014893a09ac8 content_type: application/pdf creator: dernst date_created: 2025-04-22T09:00:08Z date_updated: 2025-04-22T09:00:08Z file_id: '19604' file_name: 2025_PhysReviewResearch_Valentini.pdf file_size: 1977581 relation: main_file success: 1 file_date_updated: 2025-04-22T09:00:08Z has_accepted_license: '1' intvolume: ' 7' issue: '2' language: - iso: eng month: '04' oa: 1 oa_version: Published Version project: - _id: 34a66131-11ca-11ed-8bc3-a31681c6b03e grant_number: F8606 name: 'Center for Correlated Quantum Materials and Solid State Quantum Systems: Conventional and unconventional topological superconductors' publication: Physical Review Research publication_identifier: issn: - 2643-1564 publication_status: published publisher: American Physical Society quality_controlled: '1' scopus_import: '1' status: public title: 'Subgap transport in superconductor-semiconductor hybrid islands: Weak and strong coupling regimes' tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 7 year: '2025' ... --- OA_place: publisher OA_type: hybrid PlanS_conform: '1' _id: '19598' abstract: - lang: eng text: We establish universal Gaussian fluctuations for the mesoscopic linear eigenvalue statistics in the vicinity of the cusp-like singularities of the limiting spectral density for Wigner-type random matrices. Prior to this work, the linear eigenvalue statistics at the cusp-like singularities were not studied in any ensemble. Our analysis covers not only the exact cusps but the entire transitionary regime from the square-root singularity at a regular edge through the sharp cusp to the bulk. We identify a new one-parameter family of functionals that govern the limiting bias and variance, continuously interpolating between the previously known formulas in the bulk and at a regular edge. Since cusps are the only possible singularities besides the regular edges, our result gives a complete description of the linear eigenvalue statistics in all regimes. acknowledgement: I would like to express my gratitude to László Erdős for his careful guidance and supervision of my work. I am also thankful to Jana Reker and Joscha Henheik for many helpful discussions. Open access funding provided by Institute of Science and Technology (IST Austria). article_processing_charge: Yes (via OA deal) article_type: original arxiv: 1 author: - first_name: Volodymyr full_name: Riabov, Volodymyr id: 1949f904-edfb-11eb-afb5-e2dfddabb93b last_name: Riabov citation: ama: Riabov V. Linear Eigenvalue statistics at the cusp. Probability Theory and Related Fields. 2025;193:1183-1237. doi:10.1007/s00440-025-01373-w apa: Riabov, V. (2025). Linear Eigenvalue statistics at the cusp. Probability Theory and Related Fields. Springer Nature. https://doi.org/10.1007/s00440-025-01373-w chicago: Riabov, Volodymyr. “Linear Eigenvalue Statistics at the Cusp.” Probability Theory and Related Fields. Springer Nature, 2025. https://doi.org/10.1007/s00440-025-01373-w. ieee: V. Riabov, “Linear Eigenvalue statistics at the cusp,” Probability Theory and Related Fields, vol. 193. Springer Nature, pp. 1183–1237, 2025. ista: Riabov V. 2025. Linear Eigenvalue statistics at the cusp. Probability Theory and Related Fields. 193, 1183–1237. mla: Riabov, Volodymyr. “Linear Eigenvalue Statistics at the Cusp.” Probability Theory and Related Fields, vol. 193, Springer Nature, 2025, pp. 1183–237, doi:10.1007/s00440-025-01373-w. short: V. Riabov, Probability Theory and Related Fields 193 (2025) 1183–1237. corr_author: '1' date_created: 2025-04-20T22:01:28Z date_published: 2025-12-01T00:00:00Z date_updated: 2026-04-07T12:32:19Z day: '01' ddc: - '510' department: - _id: LaEr doi: 10.1007/s00440-025-01373-w external_id: arxiv: - '2307.07432' isi: - '001466997300001' file: - access_level: open_access checksum: 700229b280725c0d6aad0d71362cce5f content_type: application/pdf creator: dernst date_created: 2025-12-30T13:10:05Z date_updated: 2025-12-30T13:10:05Z file_id: '20916' file_name: 2025_ProbTheoryRelatFields_Riabov.pdf file_size: 919213 relation: main_file success: 1 file_date_updated: 2025-12-30T13:10:05Z has_accepted_license: '1' intvolume: ' 193' isi: 1 language: - iso: eng month: '12' oa: 1 oa_version: Published Version page: 1183-1237 publication: Probability Theory and Related Fields publication_identifier: eissn: - 1432-2064 issn: - 0178-8051 publication_status: published publisher: Springer Nature quality_controlled: '1' related_material: record: - id: '20575' relation: dissertation_contains status: public scopus_import: '1' status: public title: Linear Eigenvalue statistics at the cusp tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 193 year: '2025' ... --- OA_place: publisher OA_type: hybrid PlanS_conform: '1' _id: '19599' abstract: - lang: eng text: Advances in nickel catalysis have significantly broadened the synthetic chemists’ toolbox, particularly through methodologies leveraging paramagnetic nickel species via photoredox catalysis or electrochemistry. Key to these reactions is the oxidation state modulation of nickel via single-electron transfer events. Recent mechanistic studies indicate that C(sp2)–heteroatom bond formations proceed through NiI/NiIII cycles. Related C(sp2)–C(sp3) cross-couplings operate via the photocatalytic generation of C-centered radicals and a catalytic cycle that involves Ni0, NiI, and NiIII species. Here, we show that light-mediated nickel-catalyzed C(sp2)–C(sp3) bond formations can be carried out without using exogenous photoredox catalysts but with a photoactive ligand. In a pursuit of expanding the scope of C(sp2)–heteroatom couplings using donor–acceptor ligands, we identified a photoactive nickel complex capable of catalyzing cross-couplings between aryl halides and benzyltrifluoroborate salts. Mechanistic investigations provide evidence that transmetalation between a photochemically generated NiI species and the organoboron compound is the key catalytic step in a NiI/NiIII catalytic cycle under these conditions. acknowledged_ssus: - _id: LifeSc - _id: NMR acknowledgement: This research was supported by the Scientific Service Units (SSU) of ISTA through resources provided by the Lab Support Facility (LSF), Mass Spec Facility, and NMR Facility. We gratefully acknowledge the Institute of Science and Technology Austria (ISTA) and the Max-Planck Society for their generous financial support. R.M.v.d.V. and B.P. thank the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy – EXC 2008 – 390540038 – UniSysCat for funding. B.P. thanks the DFG (PI 1635/2-19), the Boehringer Ingelheim Foundation (Plus 3 Perspectives Programme), and the FWF (Austrian Science Fund; PAT 1250924) for financial support. J.H.B. acknowledges the Robert C. and Carolyn J. Springborn Endowment for Student Support Program at the University of Illinois Urbana–Champaign. R.F.W. was supported by a fellowship from the Deutscher Akademischer Austauschdienst (DAAD). We thank Dr. John J. Molloy (MPICI) for scientific discussions. article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Lucia full_name: Anghileri, Lucia id: 7b65e46e-1f51-11f0-8ea0-faa153157f5e last_name: Anghileri - first_name: Haralds full_name: Baunis, Haralds id: 2eea55ec-e8ec-11ed-86cb-d9c76787acfe last_name: Baunis - first_name: Aleksander full_name: Bena, Aleksander id: 4197c39e-e8ec-11ed-86cb-afed934cd664 last_name: Bena - first_name: Christos full_name: Giannoudis, Christos id: 1bd506c6-e8ec-11ed-86cb-d495f63f2dcd last_name: Giannoudis - first_name: John H. full_name: Burke, John H. last_name: Burke - first_name: Susanne full_name: Reischauer, Susanne last_name: Reischauer - first_name: Christoph full_name: Merschjann, Christoph last_name: Merschjann - first_name: Rachel F. full_name: Wallick, Rachel F. last_name: Wallick - first_name: Tarek full_name: Al Said, Tarek last_name: Al Said - first_name: Callum E full_name: Adams, Callum E id: 126d6d0f-fdc1-11ee-bb4a-9f462709fa9d last_name: Adams - first_name: Gianluca full_name: Simionato, Gianluca last_name: Simionato - first_name: Sergey full_name: Kovalenko, Sergey last_name: Kovalenko - first_name: Luca full_name: Dell’Amico, Luca last_name: Dell’Amico - first_name: Renske M. full_name: Van Der Veen, Renske M. last_name: Van Der Veen - first_name: Bartholomäus full_name: Pieber, Bartholomäus id: 93e5e5b2-0da6-11ed-8a41-af589a024726 last_name: Pieber orcid: 0000-0001-8689-388X citation: ama: Anghileri L, Baunis H, Bena A, et al. Evidence for a unifying NiI/NiIII mechanism in light-mediated cross-coupling catalysis. Journal of the American Chemical Society. 2025;147(16):13169–13179. doi:10.1021/jacs.4c16050 apa: Anghileri, L., Baunis, H., Bena, A., Giannoudis, C., Burke, J. H., Reischauer, S., … Pieber, B. (2025). Evidence for a unifying NiI/NiIII mechanism in light-mediated cross-coupling catalysis. Journal of the American Chemical Society. American Chemical Society. https://doi.org/10.1021/jacs.4c16050 chicago: Anghileri, Lucia, Haralds Baunis, Aleksander Bena, Christos Giannoudis, John H. Burke, Susanne Reischauer, Christoph Merschjann, et al. “Evidence for a Unifying NiI/NiIII Mechanism in Light-Mediated Cross-Coupling Catalysis.” Journal of the American Chemical Society. American Chemical Society, 2025. https://doi.org/10.1021/jacs.4c16050. ieee: L. Anghileri et al., “Evidence for a unifying NiI/NiIII mechanism in light-mediated cross-coupling catalysis,” Journal of the American Chemical Society, vol. 147, no. 16. American Chemical Society, pp. 13169–13179, 2025. ista: Anghileri L, Baunis H, Bena A, Giannoudis C, Burke JH, Reischauer S, Merschjann C, Wallick RF, Al Said T, Adams CE, Simionato G, Kovalenko S, Dell’Amico L, Van Der Veen RM, Pieber B. 2025. Evidence for a unifying NiI/NiIII mechanism in light-mediated cross-coupling catalysis. Journal of the American Chemical Society. 147(16), 13169–13179. mla: Anghileri, Lucia, et al. “Evidence for a Unifying NiI/NiIII Mechanism in Light-Mediated Cross-Coupling Catalysis.” Journal of the American Chemical Society, vol. 147, no. 16, American Chemical Society, 2025, pp. 13169–13179, doi:10.1021/jacs.4c16050. short: L. Anghileri, H. Baunis, A. Bena, C. Giannoudis, J.H. Burke, S. Reischauer, C. Merschjann, R.F. Wallick, T. Al Said, C.E. Adams, G. Simionato, S. Kovalenko, L. Dell’Amico, R.M. Van Der Veen, B. Pieber, Journal of the American Chemical Society 147 (2025) 13169–13179. corr_author: '1' date_created: 2025-04-20T22:01:28Z date_published: 2025-04-11T00:00:00Z date_updated: 2025-10-02T08:22:12Z day: '11' ddc: - '540' department: - _id: BaPi doi: 10.1021/jacs.4c16050 external_id: isi: - '001465858000001' pmid: - '40211781' file: - access_level: open_access checksum: 7f2b6a3c23b062490f37cce10ced46aa content_type: application/pdf creator: dernst date_created: 2025-08-05T13:04:42Z date_updated: 2025-08-05T13:04:42Z file_id: '20137' file_name: 2025_JACS_Anghileri.pdf file_size: 4179314 relation: main_file success: 1 file_date_updated: 2025-08-05T13:04:42Z has_accepted_license: '1' intvolume: ' 147' isi: 1 issue: '16' language: - iso: eng month: '04' oa: 1 oa_version: Published Version page: 13169–13179 pmid: 1 project: - _id: 8f1d607d-16d5-11f0-9cad-ab453295ba5e grant_number: PAT 1250924 name: Photoactive ligands for transformative nickel catalysis publication: Journal of the American Chemical Society publication_identifier: eissn: - 1520-5126 issn: - 0002-7863 publication_status: published publisher: American Chemical Society quality_controlled: '1' scopus_import: '1' status: public title: Evidence for a unifying NiI/NiIII mechanism in light-mediated cross-coupling catalysis tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 147 year: '2025' ... --- OA_place: repository OA_type: green _id: '19600' abstract: - lang: eng text: In this work, we explore route discovery in private payment channel networks. We first determine what “ideal" privacy for a routing protocol means in this setting. We observe that protocols achieving this strong privacy definition exist by leveraging Multi-Party Computation but they are inherently inefficient as they must involve the entire network. We then present protocols with weaker privacy guarantees but much better efficiency (involving only a small fraction of the nodes). The core idea is that both sender and receiver gossip a message which propagates through the network, and the moment any node in the network receives both messages, a path is found. In our first protocol the message is always sent to all neighbouring nodes with a delay proportional to the fees of that edge. In our second protocol the message is only sent to one neighbour chosen randomly with a probability proportional to its degree. We additionally propose a more realistic notion of privacy in order to measure the privacy leakage of our protocols in practice. Our realistic notion of privacy challenges an adversary that join the network with a fixed budget to create channels to guess the sender and receiver of a transaction upon receiving messages from our protocols. Simulations of our protocols on the Lightning network topology (for random transactions and uniform fees) show that 1) forming edges with high degree nodes is a more effective attack strategy for the adversary, 2) there is a tradeoff between the number of nodes involved in our protocols (privacy) and the optimality of the discovered path, and 3) our protocols involve a very small fraction of the network on average. acknowledgement: This work was supported in part by the ERC CoG 863818 (ForM-SMArt), Austrian Science Fund (FWF) 10.55776/COE12, and MOE-T2EP20122-0014 (Data-Driven Distributed Algorithms) grants. alternative_title: - LNCS article_processing_charge: No author: - first_name: Zeta full_name: Avarikioti, Zeta last_name: Avarikioti - first_name: Mahsa full_name: Bastankhah, Mahsa last_name: Bastankhah - first_name: Mohammad Ali full_name: Maddah-Ali, Mohammad Ali last_name: Maddah-Ali - first_name: Krzysztof Z full_name: Pietrzak, Krzysztof Z id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87 last_name: Pietrzak orcid: 0000-0002-9139-1654 - first_name: Jakub full_name: Svoboda, Jakub id: 130759D2-D7DD-11E9-87D2-DE0DE6697425 last_name: Svoboda orcid: 0000-0002-1419-3267 - first_name: Michelle X full_name: Yeo, Michelle X id: 2D82B818-F248-11E8-B48F-1D18A9856A87 last_name: Yeo orcid: 0009-0001-3676-4809 citation: ama: 'Avarikioti Z, Bastankhah M, Maddah-Ali MA, Pietrzak KZ, Svoboda J, Yeo MX. Route discovery in private payment channel networks. In: Computer Security. ESORICS 2024 International Workshops. Vol 15263. Springer Nature; 2025:207-223. doi:10.1007/978-3-031-82349-7_15' apa: 'Avarikioti, Z., Bastankhah, M., Maddah-Ali, M. A., Pietrzak, K. Z., Svoboda, J., & Yeo, M. X. (2025). Route discovery in private payment channel networks. In Computer Security. ESORICS 2024 International Workshops (Vol. 15263, pp. 207–223). Bydgoszcz, Poland: Springer Nature. https://doi.org/10.1007/978-3-031-82349-7_15' chicago: Avarikioti, Zeta, Mahsa Bastankhah, Mohammad Ali Maddah-Ali, Krzysztof Z Pietrzak, Jakub Svoboda, and Michelle X Yeo. “Route Discovery in Private Payment Channel Networks.” In Computer Security. ESORICS 2024 International Workshops, 15263:207–23. Springer Nature, 2025. https://doi.org/10.1007/978-3-031-82349-7_15. ieee: Z. Avarikioti, M. Bastankhah, M. A. Maddah-Ali, K. Z. Pietrzak, J. Svoboda, and M. X. Yeo, “Route discovery in private payment channel networks,” in Computer Security. ESORICS 2024 International Workshops, Bydgoszcz, Poland, 2025, vol. 15263, pp. 207–223. ista: 'Avarikioti Z, Bastankhah M, Maddah-Ali MA, Pietrzak KZ, Svoboda J, Yeo MX. 2025. Route discovery in private payment channel networks. Computer Security. ESORICS 2024 International Workshops. ESORICS: European Symposium on Research in Computer Security, LNCS, vol. 15263, 207–223.' mla: Avarikioti, Zeta, et al. “Route Discovery in Private Payment Channel Networks.” Computer Security. ESORICS 2024 International Workshops, vol. 15263, Springer Nature, 2025, pp. 207–23, doi:10.1007/978-3-031-82349-7_15. short: Z. Avarikioti, M. Bastankhah, M.A. Maddah-Ali, K.Z. Pietrzak, J. Svoboda, M.X. Yeo, in:, Computer Security. ESORICS 2024 International Workshops, Springer Nature, 2025, pp. 207–223. conference: end_date: 2024-09-20 location: Bydgoszcz, Poland name: 'ESORICS: European Symposium on Research in Computer Security' start_date: 2024-09-16 date_created: 2025-04-20T22:01:28Z date_published: 2025-04-01T00:00:00Z date_updated: 2025-11-05T07:52:35Z day: '01' department: - _id: KrPi - _id: KrCh doi: 10.1007/978-3-031-82349-7_15 ec_funded: 1 intvolume: ' 15263' language: - iso: eng main_file_link: - open_access: '1' url: https://eprint.iacr.org/2021/1539 month: '04' oa: 1 oa_version: Submitted Version page: 207-223 project: - _id: 0599E47C-7A3F-11EA-A408-12923DDC885E call_identifier: H2020 grant_number: '863818' name: 'Formal Methods for Stochastic Models: Algorithms and Applications' publication: Computer Security. ESORICS 2024 International Workshops publication_identifier: eissn: - 1611-3349 isbn: - '9783031823480' issn: - 0302-9743 publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: Route discovery in private payment channel networks type: conference user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 15263 year: '2025' ... --- OA_place: publisher OA_type: hybrid _id: '19601' abstract: - lang: eng text: In land plants, the signalling molecule auxin profoundly controls growth and development, chiefly through a transcriptional response system. The auxin response is mediated by modulating the activity of DNA-binding auxin response factor (ARF) proteins. The concentrations and stoichiometry of the competing A- and B-class ARFs define cells’ capacity for auxin response. In the minimal auxin response system of the liverwort Marchantia polymorpha, both A- and B-ARFs are unstable, but the underlying mechanisms, developmental relevance and evolutionary history of this instability are unknown. Here we identify a minimal motif that is necessary for MpARF2 (B-class) degradation and show that it is critical for development and the auxin response. Through comparative analysis and motif swaps among all ARF classes in extant algae and land plants, we infer that the emergence of ARF instability probably occurred in the ancestor of the A- and B-ARF clades and, therefore, preceded or coincided with the origin of the auxin response system. acknowledgement: We thank S. Woudenberg, S. Valk and J. Rienstra for help and advice, A. Kuhn for comments on the paper and M. Prigge and M. Estelle for helpful discussions. This work was supported by a grant from Netherlands Organization for Scientific Research (NWO; OCENW.M20.031 to J.W.B.), a Marie Skłodowska-Curie Individual Fellowship (H2020-MSCA-IF-2020 contract number to J.H.G.) and a research grant from the Human Frontiers Research Program (HFSP; grant RGP0015/2022 to D.W.). article_processing_charge: Yes (in subscription journal) article_type: letter_note author: - first_name: Martijn full_name: De Roij, Martijn last_name: De Roij - first_name: Jorge full_name: Hernández García, Jorge last_name: Hernández García - first_name: Shubhajit full_name: Das, Shubhajit id: b08969a4-f2a5-11ed-b6c4-ff0f10b7d0be last_name: Das - first_name: Jan Willem full_name: Borst, Jan Willem last_name: Borst - first_name: Dolf full_name: Weijers, Dolf last_name: Weijers citation: ama: De Roij M, Hernández García J, Das S, Borst JW, Weijers D. ARF degradation defines a deeply conserved step in auxin response. Nature Plants. 2025;11:717-724. doi:10.1038/s41477-025-01975-1 apa: De Roij, M., Hernández García, J., Das, S., Borst, J. W., & Weijers, D. (2025). ARF degradation defines a deeply conserved step in auxin response. Nature Plants. Springer Nature. https://doi.org/10.1038/s41477-025-01975-1 chicago: De Roij, Martijn, Jorge Hernández García, Shubhajit Das, Jan Willem Borst, and Dolf Weijers. “ARF Degradation Defines a Deeply Conserved Step in Auxin Response.” Nature Plants. Springer Nature, 2025. https://doi.org/10.1038/s41477-025-01975-1. ieee: M. De Roij, J. Hernández García, S. Das, J. W. Borst, and D. Weijers, “ARF degradation defines a deeply conserved step in auxin response,” Nature Plants, vol. 11. Springer Nature, pp. 717–724, 2025. ista: De Roij M, Hernández García J, Das S, Borst JW, Weijers D. 2025. ARF degradation defines a deeply conserved step in auxin response. Nature Plants. 11, 717–724. mla: De Roij, Martijn, et al. “ARF Degradation Defines a Deeply Conserved Step in Auxin Response.” Nature Plants, vol. 11, Springer Nature, 2025, pp. 717–24, doi:10.1038/s41477-025-01975-1. short: M. De Roij, J. Hernández García, S. Das, J.W. Borst, D. Weijers, Nature Plants 11 (2025) 717–724. date_created: 2025-04-20T22:01:28Z date_published: 2025-04-11T00:00:00Z date_updated: 2025-12-30T07:28:49Z day: '11' ddc: - '580' department: - _id: JiFr doi: 10.1038/s41477-025-01975-1 external_id: pmid: - '40216983' file: - access_level: open_access checksum: 8225c1899bb2f39f9a1707cc0697a052 content_type: application/pdf creator: dernst date_created: 2025-12-30T07:28:09Z date_updated: 2025-12-30T07:28:09Z file_id: '20882' file_name: 2025_NaturePlants_deRoij.pdf file_size: 7062474 relation: main_file success: 1 file_date_updated: 2025-12-30T07:28:09Z has_accepted_license: '1' intvolume: ' 11' language: - iso: eng month: '04' oa: 1 oa_version: Published Version page: 717-724 pmid: 1 publication: Nature Plants publication_identifier: eissn: - 2055-0278 publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: ARF degradation defines a deeply conserved step in auxin response tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 11 year: '2025' ... --- OA_place: publisher OA_type: hybrid PlanS_conform: '1' _id: '19602' abstract: - lang: eng text: N4-methylcytosine (4mC) is an important DNA modification in prokaryotes, but its relevance and even its presence in eukaryotes have been mysterious. Here we show that spermatogenesis in the liverwort Marchantia polymorpha involves two waves of extensive DNA methylation reprogramming. First, 5-methylcytosine (5mC) expands from transposons to the entire genome. Notably, the second wave installs 4mC throughout genic regions, covering over 50% of CG sites in sperm. 4mC requires a methyltransferase (MpDN4MT1a) that is specifically expressed during late spermiogenesis. Deletion of MpDN4MT1a alters the sperm transcriptome, causes sperm swimming and fertility defects, and impairs post-fertilization development. Our results reveal extensive 4mC in a eukaryote, identify a family of eukaryotic methyltransferases, and elucidate the biological functions of 4mC in reproductive development, thereby expanding the repertoire of functional eukaryotic DNA modifications. acknowledged_ssus: - _id: Bio - _id: ScienComp acknowledgement: We thank Sir Richard Roberts (NEB) for the kind gift of anti-4mC antibodies. We are also grateful to the JIC Small Molecule Mass Spectrometry (Lionel Hill) and Chemistry (Martin Rejzek) platforms as well as the High Resolution Metabolomics Laboratory (Manfred Beckmann, Aberystwyth University) for their assistance with LC-MS. Additionally, we acknowledge the assistance of the JIC Bioimaging Facility and ISTA Imaging and Optics Facility for microscopy. Finally, we appreciate the High Performance Computing resources provided by the ISTA Scientific Computing Facility and Norwich BioScience Institute Partnership Computing Infrastructure. This work was funded by a Sainsbury Charitable Foundation studentship (J.W.), a UKRI-BBSRC Doctoral Training Partnerships studentship (BBT0087171 to J.T.), a European Research Council Starting Grant (“SexMeth” 804981 to J.W., S.X., and X.F.), two Biotechnology and Biological Sciences Research Council (BBSRC) grants (BBS0096201 and BBP0135111 to J.Z., M.V., and X.F.), an EMBO Long Term Fellowship (Y.L.), an ISTA Bridge Fellowship (S.X.), and ISTA core funding (Y.Y. and X.F.). article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: James full_name: Walker, James last_name: Walker - first_name: Jingyi full_name: Zhang, Jingyi last_name: Zhang - first_name: Yalin full_name: Liu, Yalin last_name: Liu - first_name: Shujuan full_name: Xu, Shujuan id: 9724dd9d-f591-11ee-bd51-e97ed0652286 last_name: Xu - first_name: Yiming full_name: Yu, Yiming id: 318e643b-8b61-11ed-b69e-aafa103ec8dd last_name: Yu orcid: 0000-0002-9919-7282 - first_name: Martin full_name: Vickers, Martin last_name: Vickers - first_name: Weizhi full_name: Ouyang, Weizhi id: fec73395-8b60-11ed-b69e-927fda99c743 last_name: Ouyang - first_name: Judit full_name: Tálas, Judit last_name: Tálas - first_name: Liam full_name: Dolan, Liam last_name: Dolan - first_name: Keiji full_name: Nakajima, Keiji last_name: Nakajima - first_name: Xiaoqi full_name: Feng, Xiaoqi id: e0164712-22ee-11ed-b12a-d80fcdf35958 last_name: Feng orcid: 0000-0002-4008-1234 citation: ama: Walker J, Zhang J, Liu Y, et al. Extensive N4 cytosine methylation is essential for Marchantia sperm function. Cell. 2025;188(11):2890-2906.e14. doi:10.1016/j.cell.2025.03.014 apa: Walker, J., Zhang, J., Liu, Y., Xu, S., Yu, Y., Vickers, M., … Feng, X. (2025). Extensive N4 cytosine methylation is essential for Marchantia sperm function. Cell. Elsevier. https://doi.org/10.1016/j.cell.2025.03.014 chicago: Walker, James, Jingyi Zhang, Yalin Liu, Shujuan Xu, Yiming Yu, Martin Vickers, Weizhi Ouyang, et al. “Extensive N4 Cytosine Methylation Is Essential for Marchantia Sperm Function.” Cell. Elsevier, 2025. https://doi.org/10.1016/j.cell.2025.03.014. ieee: J. Walker et al., “Extensive N4 cytosine methylation is essential for Marchantia sperm function,” Cell, vol. 188, no. 11. Elsevier, p. 2890–2906.e14, 2025. ista: Walker J, Zhang J, Liu Y, Xu S, Yu Y, Vickers M, Ouyang W, Tálas J, Dolan L, Nakajima K, Feng X. 2025. Extensive N4 cytosine methylation is essential for Marchantia sperm function. Cell. 188(11), 2890–2906.e14. mla: Walker, James, et al. “Extensive N4 Cytosine Methylation Is Essential for Marchantia Sperm Function.” Cell, vol. 188, no. 11, Elsevier, 2025, p. 2890–2906.e14, doi:10.1016/j.cell.2025.03.014. short: J. Walker, J. Zhang, Y. Liu, S. Xu, Y. Yu, M. Vickers, W. Ouyang, J. Tálas, L. Dolan, K. Nakajima, X. Feng, Cell 188 (2025) 2890–2906.e14. corr_author: '1' date_created: 2025-04-20T22:01:28Z date_published: 2025-05-29T00:00:00Z date_updated: 2026-04-28T13:36:51Z day: '29' ddc: - '570' department: - _id: XiFe doi: 10.1016/j.cell.2025.03.014 ec_funded: 1 external_id: isi: - '001504744800006' pmid: - '40209706' file: - access_level: open_access checksum: 0dcc2feb368dfe7c4890093366b2dacb content_type: application/pdf creator: dernst date_created: 2025-12-29T13:40:32Z date_updated: 2025-12-29T13:40:32Z file_id: '20871' file_name: 2025_Cell_Walker.pdf file_size: 11622960 relation: main_file success: 1 file_date_updated: 2025-12-29T13:40:32Z has_accepted_license: '1' intvolume: ' 188' isi: 1 issue: '11' language: - iso: eng month: '05' oa: 1 oa_version: Published Version page: 2890-2906.e14 pmid: 1 project: - _id: bdb51a6e-d553-11ed-ba76-c2025f3d5725 call_identifier: H2020 grant_number: '804981' name: Establishment, modulation and inheritance of sexual lineage specific DNA methylation in plants publication: Cell publication_identifier: eissn: - 1097-4172 issn: - 0092-8674 publication_status: published publisher: Elsevier quality_controlled: '1' related_material: link: - description: News on ISTA website relation: press_release url: https://ista.ac.at/en/news/from-bacterial-immunity-to-plant-sex/ scopus_import: '1' status: public title: Extensive N4 cytosine methylation is essential for Marchantia sperm function tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd volume: 188 year: '2025' ... --- OA_place: publisher OA_type: hybrid _id: '19603' abstract: - lang: eng text: "MaxCut is a classical NP-complete problem and a crucial building block in many\r\ncombinatorial algorithms. The famousEdwards-Erdös bound states that any connected\r\ngraph on n vertices with m edges contains a cut of size at least m/2 + n−1/4 . Crowston,\r\nJones and Mnich [Algorithmica, 2015] showed that the MaxCut problem on simple\r\nconnected graphs admits an FPT algorithm, where the parameter k is the difference\r\nbetween the desired cut size c and the lower bound given by the Edwards-Erdös\r\nbound. This was later improved by Etscheid and Mnich [Algorithmica, 2017] to run\r\nin parameterized linear time, i.e., f (k) · O(m). We improve upon this result in two\r\nways: Firstly, we extend the algorithm to work also for multigraphs (alternatively,\r\ngraphs with positive integer weights). Secondly, we change the parameter; instead of\r\nthe difference to the Edwards-Erdös bound, we use the difference to the Poljak-Turzík\r\nbound. The Poljak-Turzík bound states that any weighted graph G has a cut of weight\r\nat least w(G)/2 + wMSF (G)/4 , where w(G) denotes the total weight of G, and wMSF (G)\r\ndenotes the weight of its minimum spanning forest. In connected simple graphs the\r\ntwo bounds are equivalent, but for multigraphs the Poljak-Turzík bound can be larger\r\nand thus yield a smaller parameter k. Our algorithm also runs in parameterized linear\r\ntime, i.e., f (k) · O(m + n)." acknowledgement: "Kalina Petrova is supported by the Swiss National Science Foundation, grant no. CRSII5 173721, and also receives funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034413. Simon Weber is supported by the Swiss National Science Foundation under project no. 204320.\r\nOpen access funding provided by Swiss Federal Institute of Technology Zurich." article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Jonas full_name: Lill, Jonas last_name: Lill - first_name: Kalina H full_name: Petrova, Kalina H id: 554ff4e4-f325-11ee-b0c4-a10dbd523381 last_name: Petrova - first_name: Simon full_name: Weber, Simon last_name: Weber citation: ama: Lill J, Petrova KH, Weber S. Linear-time MaxCut in multigraphs parameterized above the Poljak-Turzík bound. Algorithmica. 2025;87:983-1007. doi:10.1007/s00453-025-01306-y apa: Lill, J., Petrova, K. H., & Weber, S. (2025). Linear-time MaxCut in multigraphs parameterized above the Poljak-Turzík bound. Algorithmica. Springer Nature. https://doi.org/10.1007/s00453-025-01306-y chicago: Lill, Jonas, Kalina H Petrova, and Simon Weber. “Linear-Time MaxCut in Multigraphs Parameterized above the Poljak-Turzík Bound.” Algorithmica. Springer Nature, 2025. https://doi.org/10.1007/s00453-025-01306-y. ieee: J. Lill, K. H. Petrova, and S. Weber, “Linear-time MaxCut in multigraphs parameterized above the Poljak-Turzík bound,” Algorithmica, vol. 87. Springer Nature, pp. 983–1007, 2025. ista: Lill J, Petrova KH, Weber S. 2025. Linear-time MaxCut in multigraphs parameterized above the Poljak-Turzík bound. Algorithmica. 87, 983–1007. mla: Lill, Jonas, et al. “Linear-Time MaxCut in Multigraphs Parameterized above the Poljak-Turzík Bound.” Algorithmica, vol. 87, Springer Nature, 2025, pp. 983–1007, doi:10.1007/s00453-025-01306-y. short: J. Lill, K.H. Petrova, S. Weber, Algorithmica 87 (2025) 983–1007. date_created: 2025-04-20T22:01:28Z date_published: 2025-07-01T00:00:00Z date_updated: 2026-01-05T13:46:08Z day: '01' ddc: - '510' department: - _id: MaKw doi: 10.1007/s00453-025-01306-y ec_funded: 1 external_id: isi: - '001463103800001' file: - access_level: open_access checksum: eab3f1834b0ba347b05ae9897729c0ad content_type: application/pdf creator: dernst date_created: 2026-01-05T13:45:57Z date_updated: 2026-01-05T13:45:57Z file_id: '20957' file_name: 2025_Algorithmica_Lill.pdf file_size: 448554 relation: main_file success: 1 file_date_updated: 2026-01-05T13:45:57Z has_accepted_license: '1' intvolume: ' 87' isi: 1 language: - iso: eng month: '07' oa: 1 oa_version: Published Version page: 983-1007 project: - _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c call_identifier: H2020 grant_number: '101034413' name: 'IST-BRIDGE: International postdoctoral program' publication: Algorithmica publication_identifier: eissn: - 1432-0541 issn: - 0178-4617 publication_status: published publisher: Springer Nature quality_controlled: '1' related_material: record: - id: '18758' relation: earlier_version status: public scopus_import: '1' status: public title: Linear-time MaxCut in multigraphs parameterized above the Poljak-Turzík bound tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 87 year: '2025' ... --- OA_place: publisher OA_type: hybrid _id: '19617' abstract: - lang: eng text: In this article, we propose a method for generating single microwave photons in superconducting circuits. We theoretically show that pure single microwave photons can be generated on demand and tuned over a large frequency band by making use of Landau-Zener transitions under a rapid sweep of a control parameter. We devise a protocol that enables fast control of the frequency of the emitted photon over two octaves, without requiring extensive calibration. Additionally, we make theoretical estimates of the generation efficiency, tunability, purity, and linewidth of the photons emitted using this method for both charge- and flux-qubit-based architectures. We also provide estimates of the optimal device parameters required for these architectures to realize the device. acknowledgement: The authors acknowledge the support of DST-INSPIRE Fellowship No. IF180339 and DST-SERB Core Research Grant No. CRG/2018/002129. S.H. acknowledges the support of the Kishore Vaigyanik Protsahan Yojana (KVPY). S.H. also acknowledges helpful discussions with Harsh Arora and Johannes Fink. article_number: '044042' article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Samarth full_name: Hawaldar, Samarth id: 221708e1-1ff6-11ee-9fa6-85146607433e last_name: Hawaldar orcid: 0000-0002-1965-4309 - first_name: Siddhi Satish full_name: Khaire, Siddhi Satish last_name: Khaire - first_name: Per full_name: Delsing, Per last_name: Delsing - first_name: Baladitya full_name: Suri, Baladitya last_name: Suri citation: ama: Hawaldar S, Khaire SS, Delsing P, Suri B. On-demand single-microwave-photon source in a superconducting circuit with wideband frequency tunability. Physical Review Applied. 2025;23(4). doi:10.1103/physrevapplied.23.044042 apa: Hawaldar, S., Khaire, S. S., Delsing, P., & Suri, B. (2025). On-demand single-microwave-photon source in a superconducting circuit with wideband frequency tunability. Physical Review Applied. American Physical Society. https://doi.org/10.1103/physrevapplied.23.044042 chicago: Hawaldar, Samarth, Siddhi Satish Khaire, Per Delsing, and Baladitya Suri. “On-Demand Single-Microwave-Photon Source in a Superconducting Circuit with Wideband Frequency Tunability.” Physical Review Applied. American Physical Society, 2025. https://doi.org/10.1103/physrevapplied.23.044042. ieee: S. Hawaldar, S. S. Khaire, P. Delsing, and B. Suri, “On-demand single-microwave-photon source in a superconducting circuit with wideband frequency tunability,” Physical Review Applied, vol. 23, no. 4. American Physical Society, 2025. ista: Hawaldar S, Khaire SS, Delsing P, Suri B. 2025. On-demand single-microwave-photon source in a superconducting circuit with wideband frequency tunability. Physical Review Applied. 23(4), 044042. mla: Hawaldar, Samarth, et al. “On-Demand Single-Microwave-Photon Source in a Superconducting Circuit with Wideband Frequency Tunability.” Physical Review Applied, vol. 23, no. 4, 044042, American Physical Society, 2025, doi:10.1103/physrevapplied.23.044042. short: S. Hawaldar, S.S. Khaire, P. Delsing, B. Suri, Physical Review Applied 23 (2025). corr_author: '1' date_created: 2025-04-24T06:34:07Z date_published: 2025-04-18T00:00:00Z date_updated: 2025-09-30T12:17:33Z day: '18' ddc: - '539' department: - _id: GradSch - _id: JoFi doi: 10.1103/physrevapplied.23.044042 external_id: isi: - '001490745300002' file: - access_level: open_access checksum: 582b2ed6afb654300cabf0e3add14ca8 content_type: application/pdf creator: shawalda date_created: 2025-04-24T06:40:22Z date_updated: 2025-04-24T06:40:22Z file_id: '19620' file_name: PhysRevApplied.23.044042.pdf file_size: 837219 relation: main_file success: 1 file_date_updated: 2025-04-24T06:40:22Z has_accepted_license: '1' intvolume: ' 23' isi: 1 issue: '4' language: - iso: eng month: '04' oa: 1 oa_version: Published Version publication: Physical Review Applied publication_identifier: issn: - 2331-7019 publication_status: published publisher: American Physical Society quality_controlled: '1' scopus_import: '1' status: public title: On-demand single-microwave-photon source in a superconducting circuit with wideband frequency tunability tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 23 year: '2025' ... --- OA_place: publisher OA_type: hybrid _id: '19621' abstract: - lang: eng text: In this paper we obtain a complete description of all indecomposable characters (central positive-definite functions) of inductive limits of the symmetric groups under block diagonal embedding. As a corollary we obtain the full classification of the isomorphism classes of these inductive limits. acknowledgement: The authors were partially supported by the “Long-term program of support of the Ukrainian research teams at the Polish Academy of Sciences carried out in collaboration with the U.S. National Academy of Sciences with the financial support of external partners”. The second author was also supported by the Austrian Science Fund (FWF) grant “Geometry of the tip of the global nilpotent cone” no. 10.55776/P35847 article_processing_charge: Yes (in subscription journal) article_type: original arxiv: 1 author: - first_name: Nikolay full_name: Nessonov, Nikolay last_name: Nessonov - first_name: Nhok T full_name: Ngo, Nhok T id: 28e53c8c-896a-11ed-bdf8-f809043ce2f0 last_name: Ngo citation: ama: Nessonov N, Ngo NT. Indecomposable characters of inductive limits of symmetric groups. Representation Theory. 2025;29(8):256-288. doi:10.1090/ert/689 apa: Nessonov, N., & Ngo, N. T. (2025). Indecomposable characters of inductive limits of symmetric groups. Representation Theory. American Mathematical Society. https://doi.org/10.1090/ert/689 chicago: Nessonov, Nikolay, and Nhok T Ngo. “Indecomposable Characters of Inductive Limits of Symmetric Groups.” Representation Theory. American Mathematical Society, 2025. https://doi.org/10.1090/ert/689. ieee: N. Nessonov and N. T. Ngo, “Indecomposable characters of inductive limits of symmetric groups,” Representation Theory, vol. 29, no. 8. American Mathematical Society, pp. 256–288, 2025. ista: Nessonov N, Ngo NT. 2025. Indecomposable characters of inductive limits of symmetric groups. Representation Theory. 29(8), 256–288. mla: Nessonov, Nikolay, and Nhok T. Ngo. “Indecomposable Characters of Inductive Limits of Symmetric Groups.” Representation Theory, vol. 29, no. 8, American Mathematical Society, 2025, pp. 256–88, doi:10.1090/ert/689. short: N. Nessonov, N.T. Ngo, Representation Theory 29 (2025) 256–288. corr_author: '1' date_created: 2025-04-24T08:48:05Z date_published: 2025-04-10T00:00:00Z date_updated: 2025-05-05T06:59:07Z day: '10' ddc: - '510' department: - _id: GradSch - _id: TaHa doi: 10.1090/ert/689 external_id: arxiv: - '2206.01964' file: - access_level: open_access checksum: f6541ea1736a7413c6d24f14d64a4dda content_type: application/pdf creator: dernst date_created: 2025-05-05T06:57:49Z date_updated: 2025-05-05T06:57:49Z file_id: '19644' file_name: 2025_RepresentationTheory_Nessonov.pdf file_size: 424364 relation: main_file success: 1 file_date_updated: 2025-05-05T06:57:49Z has_accepted_license: '1' intvolume: ' 29' issue: '8' language: - iso: eng license: https://creativecommons.org/licenses/by/3.0/ month: '04' oa: 1 oa_version: Published Version page: 256-288 project: - _id: 34b2c9cb-11ca-11ed-8bc3-a50ba74ca4a3 grant_number: P35847 name: Geometry of the tip of the global nilpotent cone publication: Representation Theory publication_identifier: issn: - 1088-4165 publication_status: published publisher: American Mathematical Society quality_controlled: '1' scopus_import: '1' status: public title: Indecomposable characters of inductive limits of symmetric groups tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/3.0/legalcode name: Creative Commons Attribution 3.0 Unported (CC BY 3.0) short: CC BY (3.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 29 year: '2025' ... --- _id: '19623' abstract: - lang: eng text: "Persistent revivals recently observed in Rydberg atom simulators have challenged our understanding of thermalization and attracted much interest to the concept of quantum many-body scars (QMBSs). QMBSs are non-thermal highly excited eigenstates that coexist with typical eigenstates in the spectrum of many-body Hamiltonians, and have since been reported in multiple theoretical models, including the so-called PXP model, approximately realized by Rydberg simulators. At the same time, questions of how common QMBSs are and in what models they are physically realized remain open. In this Letter, we demonstrate that QMBSs exist in a broader family of models that includes and generalizes PXP to longer-range constraints and states with different periodicity. We show that in each model, multiple QMBS families can be found. Each of them relies on a different approximate \U0001D530\U0001D532⁡(2) algebra, leading to oscillatory dynamics in all cases. However, in contrast to the PXP model, their observation requires launching dynamics from weakly entangled initial states rather than from a product state. QMBSs reported here may be experimentally probed using Rydberg atom simulator in the regime of longer-range Rydberg blockades." acknowledged_ssus: - _id: ScienComp acknowledgement: The authors are grateful to Zlatko Papić, Dolev Bluvstein, Nishad Maskara, Marcello Dalmonte, Thomas Iadecola, and Johannes Feldmeier for insightful discussions. A. K., M. L., and M. S. acknowledge support by the European Research Council under the European Union’s Horizon 2020 research and innovation program (Grant Agreement No. 850899). J.-Y. D. acknowledges funding from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie Grant Agreement No. 101034413. article_processing_charge: No author: - first_name: Jean-Yves Marc full_name: Desaules, Jean-Yves Marc id: 6c292945-a610-11ed-9eec-c3be1ad62a80 last_name: Desaules orcid: 0000-0002-3749-6375 citation: ama: Desaules J-YM. Research Data for “Quantum Many-Body Scars beyond the PXP Model in Rydberg Simulators.” 2025. doi:10.15479/AT:ISTA:19623 apa: Desaules, J.-Y. M. (2025). Research Data for “Quantum Many-Body Scars beyond the PXP Model in Rydberg Simulators.” Institute of Science and Technology Austria. https://doi.org/10.15479/AT:ISTA:19623 chicago: Desaules, Jean-Yves Marc. “Research Data for ‘Quantum Many-Body Scars beyond the PXP Model in Rydberg Simulators.’” Institute of Science and Technology Austria, 2025. https://doi.org/10.15479/AT:ISTA:19623. ieee: J.-Y. M. Desaules, “Research Data for ‘Quantum Many-Body Scars beyond the PXP Model in Rydberg Simulators.’” Institute of Science and Technology Austria, 2025. ista: Desaules J-YM. 2025. Research Data for ‘Quantum Many-Body Scars beyond the PXP Model in Rydberg Simulators’, Institute of Science and Technology Austria, 10.15479/AT:ISTA:19623. mla: Desaules, Jean-Yves Marc. Research Data for “Quantum Many-Body Scars beyond the PXP Model in Rydberg Simulators.” Institute of Science and Technology Austria, 2025, doi:10.15479/AT:ISTA:19623. short: J.-Y.M. Desaules, (2025). contributor: - contributor_type: researcher first_name: Aron id: ade85a9c-3200-11ee-973b-91c1eb240410 last_name: Kerschbaumer - contributor_type: researcher first_name: Marko last_name: Ljubotina - contributor_type: researcher first_name: Maksym id: 47809E7E-F248-11E8-B48F-1D18A9856A87 last_name: Serbyn orcid: 0000-0002-2399-5827 - contributor_type: researcher first_name: Jean-Yves Marc id: 6c292945-a610-11ed-9eec-c3be1ad62a80 last_name: Desaules orcid: 0000-0002-3749-6375 corr_author: '1' date_created: 2025-04-24T19:58:46Z date_published: 2025-04-24T00:00:00Z date_updated: 2026-06-10T08:40:52Z day: '24' ddc: - '530' department: - _id: MaSe doi: 10.15479/AT:ISTA:19623 ec_funded: 1 file: - access_level: open_access checksum: d073314c4dc95d93feaadbff188ce4a1 content_type: application/zip creator: jdesaule date_created: 2025-05-05T07:14:17Z date_updated: 2025-05-05T07:14:17Z file_id: '19646' file_name: Data+Code.zip file_size: 583478621 relation: main_file success: 1 - access_level: open_access checksum: d386a2364fb1147ef6dad30ad029c080 content_type: text/plain creator: jdesaule date_created: 2025-05-05T07:13:46Z date_updated: 2025-05-05T07:13:46Z file_id: '19647' file_name: readme.txt file_size: 15856 relation: main_file success: 1 file_date_updated: 2025-05-05T07:14:17Z has_accepted_license: '1' keyword: - quantum many-body scars - non-equilibrium physics - Rydberg atoms month: '04' oa: 1 oa_version: Published Version project: - _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c call_identifier: H2020 grant_number: '101034413' name: 'IST-BRIDGE: International postdoctoral program' - _id: 23841C26-32DE-11EA-91FC-C7463DDC885E call_identifier: H2020 grant_number: '850899' name: 'Non-Ergodic Quantum Matter: Universality, Dynamics and Control' publisher: Institute of Science and Technology Austria related_material: record: - id: '19664' relation: used_in_publication status: public status: public title: Research Data for "Quantum Many-Body Scars beyond the PXP Model in Rydberg Simulators" tmp: image: /images/cc_by_nc.png legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) short: CC BY-NC (4.0) type: research_data user_id: 68b8ca59-c5b3-11ee-8790-cd641c68093d year: '2025' ... --- OA_place: publisher OA_type: hybrid _id: '19625' abstract: - lang: eng text: We introduce operator-valued twisted Araki–Woods algebras. These are operator-valued versions of a class of second quantization algebras that includes q-Gaussian and q-Araki–Woods algebras and also generalize Shlyakhtenko’s von Neumann algebras generated by operator-valued semicircular variables. We develop a disintegration theory that reduces the isomorphism type of operator-valued twisted Araki–Woods algebras over type I factors to the scalar-valued case. Moreover, these algebras come with a natural weight, and we characterize its modular theory. We also give sufficient criteria that guarantee the factoriality of these algebras. acknowledgement: "The authors want to thank the organizers of YMC*A 2023 in Leuven, where this collaboration was conceived. They are grateful to Dan Voiculescu for a valuable historical remark and to Zhiyuan Yang for raising the question if operator-valued weights give rise to Tomita correspondences. R.K. was funded by IIT Kanpur through the Institute Postdoctoral Fellowship. M. W. was funded by the Austrian Science Fund (FWF) under the Esprit Programme [ESP 156]. For the purpose of Open Access, the authors have applied a CC BY public copyright licence to any Author Accepted Manuscript (AAM) version arising from this submission.\r\nOpen Access funding enabled and organized by Projekt DEAL." article_number: '110' article_processing_charge: Yes (via OA deal) article_type: original arxiv: 1 author: - first_name: R. Rahul full_name: Kumar, R. Rahul last_name: Kumar - first_name: Melchior full_name: Wirth, Melchior id: 88644358-0A0E-11EA-8FA5-49A33DDC885E last_name: Wirth orcid: 0000-0002-0519-4241 citation: ama: Kumar RR, Wirth M. Operator-valued twisted Araki–Woods algebras. Communications in Mathematical Physics. 2025;406(5). doi:10.1007/s00220-025-05285-7 apa: Kumar, R. R., & Wirth, M. (2025). Operator-valued twisted Araki–Woods algebras. Communications in Mathematical Physics. Springer Nature. https://doi.org/10.1007/s00220-025-05285-7 chicago: Kumar, R. Rahul, and Melchior Wirth. “Operator-Valued Twisted Araki–Woods Algebras.” Communications in Mathematical Physics. Springer Nature, 2025. https://doi.org/10.1007/s00220-025-05285-7. ieee: R. R. Kumar and M. Wirth, “Operator-valued twisted Araki–Woods algebras,” Communications in Mathematical Physics, vol. 406, no. 5. Springer Nature, 2025. ista: Kumar RR, Wirth M. 2025. Operator-valued twisted Araki–Woods algebras. Communications in Mathematical Physics. 406(5), 110. mla: Kumar, R. Rahul, and Melchior Wirth. “Operator-Valued Twisted Araki–Woods Algebras.” Communications in Mathematical Physics, vol. 406, no. 5, 110, Springer Nature, 2025, doi:10.1007/s00220-025-05285-7. short: R.R. Kumar, M. Wirth, Communications in Mathematical Physics 406 (2025). corr_author: '1' date_created: 2025-04-27T22:02:13Z date_published: 2025-05-01T00:00:00Z date_updated: 2025-09-30T12:19:22Z day: '01' ddc: - '510' department: - _id: JaMa doi: 10.1007/s00220-025-05285-7 external_id: arxiv: - '2406.06179' isi: - '001464170400003' pmid: - '40225194' file: - access_level: open_access checksum: 2948e8f567f20f5f837061d2c775534f content_type: application/pdf creator: dernst date_created: 2025-05-05T09:20:54Z date_updated: 2025-05-05T09:20:54Z file_id: '19650' file_name: 2025_CommMathPhysics_Kumar.pdf file_size: 650764 relation: main_file success: 1 file_date_updated: 2025-05-05T09:20:54Z has_accepted_license: '1' intvolume: ' 406' isi: 1 issue: '5' language: - iso: eng month: '05' oa: 1 oa_version: Published Version pmid: 1 project: - _id: 34c6ea2d-11ca-11ed-8bc3-c04f3c502833 grant_number: ESP156_N name: Gradient flow techniques for quantum Markov semigroups publication: Communications in Mathematical Physics publication_identifier: eissn: - 1432-0916 issn: - 0010-3616 publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: Operator-valued twisted Araki–Woods algebras tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 406 year: '2025' ... --- APC_amount: 5949 EUR OA_place: publisher OA_type: hybrid _id: '19626' abstract: - lang: eng text: Active regulation of gene expression, orchestrated by complex interactions of activators and repressors at promoters, controls the fate of organisms. In contrast, basal expression at uninduced promoters is considered to be a dynamically inert mode of nonfunctional “promoter leakiness,” merely a byproduct of transcriptional regulation. Here, we investigate the basal expression mode of the mar operon, the main regulator of intrinsic multiple antibiotic resistance in Escherichia coli, and link its dynamic properties to the noncanonical, yet highly conserved start codon of marR across Enterobacteriaceae. Real-time, single-cell measurements across tens of generations reveal that basal expression consists of rare stochastic gene expression pulses, which maximize variability in wildtype and, surprisingly, transiently accelerate cellular elongation rates. Competition experiments show that basal expression confers fitness advantages to wildtype across several transitions between exponential and stationary growth by shortening lag times. The dynamically rich basal expression of the mar operon has likely been evolutionarily maintained for its role in growth homeostasis of Enterobacteria within the gut environment, thereby allowing other ancillary gene regulatory roles to evolve, e.g., control of costly-to-induce multidrug efflux pumps. Understanding the complex selection forces governing genetic systems involved in intrinsic multidrug resistance is crucial for effective public health measures. acknowledged_ssus: - _id: Bio acknowledgement: K.J. thanks B. Wu, I. Tomanek, K. Tomasek for detailed discussions on the manuscript, all other members from the Guet laboratory for valuable feedback, R. Chait, & Imaging and Optics Facility, Institute of Science and Technology Austria for helping with microscopy, Dr. Sudha Rao and Dr. Raja Mugasimangalam, Genotypic Technology India for allowing time off to address the revisions. K.J. acknowledges Institute of Science and Technology fellowship IC1006FELL02, R.H. was supported in part by Chan Zuckerberg Initiative and Donor Advised-Fund grant 2020-225401 (https://doi.org/10.37921/120055ratwvi), O.O.B. acknowledges Fonds Zur Förderung der Wissenschaftlichen Forschung (FWF) Grant ESP253-B, R.R. acknowledges FWF Grant 10.55776/ESP219, C.C.G. acknowledges FWF I5127-B. article_number: e2413709122 article_processing_charge: Yes (in subscription journal) article_type: original author: - first_name: Kirti full_name: Jain, Kirti id: 330F0278-F248-11E8-B48F-1D18A9856A87 last_name: Jain orcid: 0000-0002-3809-0449 - first_name: Robert full_name: Hauschild, Robert id: 4E01D6B4-F248-11E8-B48F-1D18A9856A87 last_name: Hauschild orcid: 0000-0001-9843-3522 - first_name: Olga full_name: Bochkareva, Olga id: C4558D3C-6102-11E9-A62E-F418E6697425 last_name: Bochkareva orcid: 0000-0003-1006-6639 - first_name: Roderich full_name: Römhild, Roderich id: 68E56E44-62B0-11EA-B963-444F3DDC885E last_name: Römhild orcid: 0000-0001-9480-5261 - first_name: Gašper full_name: Tkačik, Gašper id: 3D494DCA-F248-11E8-B48F-1D18A9856A87 last_name: Tkačik orcid: 0000-0002-6699-1455 - first_name: Calin C full_name: Guet, Calin C id: 47F8433E-F248-11E8-B48F-1D18A9856A87 last_name: Guet orcid: 0000-0001-6220-2052 citation: ama: Jain K, Hauschild R, Bochkareva O, Römhild R, Tkačik G, Guet CC. Pulsatile basal gene expression as a fitness determinant in bacteria. Proceedings of the National Academy of Sciences. 2025;122(15). doi:10.1073/pnas.2413709122 apa: Jain, K., Hauschild, R., Bochkareva, O., Römhild, R., Tkačik, G., & Guet, C. C. (2025). Pulsatile basal gene expression as a fitness determinant in bacteria. Proceedings of the National Academy of Sciences. National Academy of Sciences. https://doi.org/10.1073/pnas.2413709122 chicago: Jain, Kirti, Robert Hauschild, Olga Bochkareva, Roderich Römhild, Gašper Tkačik, and Calin C Guet. “Pulsatile Basal Gene Expression as a Fitness Determinant in Bacteria.” Proceedings of the National Academy of Sciences. National Academy of Sciences, 2025. https://doi.org/10.1073/pnas.2413709122. ieee: K. Jain, R. Hauschild, O. Bochkareva, R. Römhild, G. Tkačik, and C. C. Guet, “Pulsatile basal gene expression as a fitness determinant in bacteria,” Proceedings of the National Academy of Sciences, vol. 122, no. 15. National Academy of Sciences, 2025. ista: Jain K, Hauschild R, Bochkareva O, Römhild R, Tkačik G, Guet CC. 2025. Pulsatile basal gene expression as a fitness determinant in bacteria. Proceedings of the National Academy of Sciences. 122(15), e2413709122. mla: Jain, Kirti, et al. “Pulsatile Basal Gene Expression as a Fitness Determinant in Bacteria.” Proceedings of the National Academy of Sciences, vol. 122, no. 15, e2413709122, National Academy of Sciences, 2025, doi:10.1073/pnas.2413709122. short: K. Jain, R. Hauschild, O. Bochkareva, R. Römhild, G. Tkačik, C.C. Guet, Proceedings of the National Academy of Sciences 122 (2025). corr_author: '1' date_created: 2025-04-27T22:02:13Z date_published: 2025-04-15T00:00:00Z date_updated: 2026-05-20T08:33:08Z day: '15' ddc: - '570' department: - _id: CaGu - _id: Bio - _id: FyKo - _id: GaTk doi: 10.1073/pnas.2413709122 external_id: isi: - '001471235200001' pmid: - '40193613' file: - access_level: open_access checksum: 115a687f40009660eb4b38b4f6559d41 content_type: application/pdf creator: dernst date_created: 2025-06-24T07:27:43Z date_updated: 2025-06-24T07:27:43Z file_id: '19888' file_name: 2025_PNAS_Jain.pdf file_size: 2949523 relation: main_file success: 1 file_date_updated: 2025-06-24T07:27:43Z has_accepted_license: '1' intvolume: ' 122' isi: 1 issue: '15' language: - iso: eng month: '04' oa: 1 oa_version: Published Version pmid: 1 project: - _id: c08e9ad1-5a5b-11eb-8a69-9d1cf3b07473 grant_number: CZI01 name: Tools for automation and feedback microscopy - _id: bd6f94d1-d553-11ed-ba76-ae9f07250f74 grant_number: E219 name: Non-canonical antibiotic interactions - _id: 34e076d6-11ca-11ed-8bc3-aec76c41a181 grant_number: I05127 name: Evolutionary analysis of gene regulation publication: Proceedings of the National Academy of Sciences publication_identifier: eissn: - 1091-6490 issn: - 0027-8424 publication_status: published publisher: National Academy of Sciences quality_controlled: '1' related_material: link: - description: News on ISTA website relation: press_release url: https://ista.ac.at/en/news/clockwork-just-for-antibiotic-resistance/ record: - id: '19294' relation: research_data status: public scopus_import: '1' status: public title: Pulsatile basal gene expression as a fitness determinant in bacteria tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 122 year: '2025' ... --- APC_amount: 2754,32 EUR OA_place: publisher OA_type: hybrid _id: '19627' abstract: - lang: eng text: Differentially private gradient descent (DP-GD) is a popular algorithm to train deep learning models with provable guarantees on the privacy of the training data. In the last decade, the problem of understanding its performance cost with respect to standard GD has received remarkable attention from the research community, which formally derived upper bounds on the excess population risk RP in different learning settings. However, existing bounds typically degrade with over-parameterization, i.e., as the number of parameters p gets larger than the number of training samples n -- a regime which is ubiquitous in current deep-learning practice. As a result, the lack of theoretical insights leaves practitioners without clear guidance, leading some to reduce the effective number of trainable parameters to improve performance, while others use larger models to achieve better results through scale. In this work, we show that in the popular random features model with quadratic loss, for any sufficiently large p , privacy can be obtained for free, i.e., |RP|=o(1) , not only when the privacy parameter ε has constant order, but also in the strongly private setting ε=o(1) . This challenges the common wisdom that over-parameterization inherently hinders performance in private learning. acknowledgement: This research was funded in whole, or in part, by the Austrian Science Fund (FWF) Grant number COE 12. For the purpose of open access, the author has applied a CC BY public copyright license to any Author Accepted Manuscript version arising from this submission. The authors were also supported by the 2019 Lopez-Loreta prize, and Simone Bombari was supported by a Google PhD fellowship. We thank Diyuan Wu, Edwige Cyffers, Francesco Pedrotti, Inbar Seroussi, Nikita P. Kalinin, Pietro Pelliconi, Roodabeh Safavi, Yizhe Zhu, and Zhichao Wang for helpful discussions. article_number: e2423072122 article_processing_charge: Yes (in subscription journal) article_type: original arxiv: 1 author: - first_name: Simone full_name: Bombari, Simone id: ca726dda-de17-11ea-bc14-f9da834f63aa last_name: Bombari - first_name: Marco full_name: Mondelli, Marco id: 27EB676C-8706-11E9-9510-7717E6697425 last_name: Mondelli orcid: 0000-0002-3242-7020 citation: ama: Bombari S, Mondelli M. Privacy for free in the overparameterized regime. Proceedings of the National Academy of Sciences. 2025;122(15). doi:10.1073/pnas.2423072122 apa: Bombari, S., & Mondelli, M. (2025). Privacy for free in the overparameterized regime. Proceedings of the National Academy of Sciences. National Academy of Sciences. https://doi.org/10.1073/pnas.2423072122 chicago: Bombari, Simone, and Marco Mondelli. “Privacy for Free in the Overparameterized Regime.” Proceedings of the National Academy of Sciences. National Academy of Sciences, 2025. https://doi.org/10.1073/pnas.2423072122. ieee: S. Bombari and M. Mondelli, “Privacy for free in the overparameterized regime,” Proceedings of the National Academy of Sciences, vol. 122, no. 15. National Academy of Sciences, 2025. ista: Bombari S, Mondelli M. 2025. Privacy for free in the overparameterized regime. Proceedings of the National Academy of Sciences. 122(15), e2423072122. mla: Bombari, Simone, and Marco Mondelli. “Privacy for Free in the Overparameterized Regime.” Proceedings of the National Academy of Sciences, vol. 122, no. 15, e2423072122, National Academy of Sciences, 2025, doi:10.1073/pnas.2423072122. short: S. Bombari, M. Mondelli, Proceedings of the National Academy of Sciences 122 (2025). corr_author: '1' date_created: 2025-04-27T22:02:13Z date_published: 2025-04-15T00:00:00Z date_updated: 2026-05-20T08:23:19Z day: '15' ddc: - '000' department: - _id: MaMo doi: 10.1073/pnas.2423072122 external_id: arxiv: - '2410.14787' isi: - '001471214000001' pmid: - '40215275' file: - access_level: open_access checksum: 1ac6f78e368d35a0cafb4d2d9bd63443 content_type: application/pdf creator: dernst date_created: 2025-05-05T07:27:54Z date_updated: 2025-05-05T07:27:54Z file_id: '19648' file_name: 2025_PNAS_Bombari.pdf file_size: 2328320 relation: main_file success: 1 file_date_updated: 2025-05-05T07:27:54Z has_accepted_license: '1' intvolume: ' 122' isi: 1 issue: '15' language: - iso: eng month: '04' oa: 1 oa_version: Published Version pmid: 1 project: - _id: 059876FA-7A3F-11EA-A408-12923DDC885E name: Prix Lopez-Loretta 2019 - Marco Mondelli - _id: 92099302-16d5-11f0-9cad-f9a785f54fbd name: 'Trustworthy Deep Learning Theory: Private Over-Parameterized Models and Robust LLMs' publication: Proceedings of the National Academy of Sciences publication_identifier: eissn: - 1091-6490 issn: - 0027-8424 publication_status: published publisher: National Academy of Sciences quality_controlled: '1' scopus_import: '1' status: public title: Privacy for free in the overparameterized regime tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 122 year: '2025' ...