--- DOAJ_listed: '1' OA_place: publisher OA_type: gold _id: '21101' abstract: - lang: eng text: It has previously been shown that the use of racemic mixtures of naturally chiral macromolecules such as protein and DNA can significantly aid the crystallogenesis process, thereby addressing one of the major bottlenecks to structure determination by X-ray crystallographic methods—that of crystal growth. Although previous studies have provided convincing evidence of the applicability of the racemic crystallization technique to DNA through the study of well-characterized DNA structures, we sought to apply this method to a historically challenging DNA sequence. For this purpose we chose a non-self-complementary DNA duplex containing the biologically-relevant Pribnow box consensus sequence ‘TATAAT’. Four racemic crystal structures of this previously un-crystallizable DNA target are reported (with resolutions in the range of 1.65–2.3 Å), with further crystallographic studies and structural analysis providing insight into the racemic crystallization process as well as structural details of this highly pertinent DNA sequence. article_processing_charge: No article_type: original author: - first_name: Pradeep K full_name: Mandal, Pradeep K id: 6a3def15-d4b4-11ef-9fa9-a24c1f545ec3 last_name: Mandal orcid: 0000-0001-5996-956X - first_name: Gavin W. full_name: Collie, Gavin W. last_name: Collie - first_name: Suresh C. full_name: Srivastava, Suresh C. last_name: Srivastava - first_name: Brice full_name: Kauffmann, Brice last_name: Kauffmann - first_name: Ivan full_name: Huc, Ivan last_name: Huc citation: ama: Mandal PK, Collie GW, Srivastava SC, Kauffmann B, Huc I. Structure elucidation of the Pribnow box consensus promoter sequence by racemic DNA crystallography. Nucleic Acids Research. 2016;44(12):5936-5943. doi:10.1093/nar/gkw367 apa: Mandal, P. K., Collie, G. W., Srivastava, S. C., Kauffmann, B., & Huc, I. (2016). Structure elucidation of the Pribnow box consensus promoter sequence by racemic DNA crystallography. Nucleic Acids Research. Oxford University Press. https://doi.org/10.1093/nar/gkw367 chicago: Mandal, Pradeep K, Gavin W. Collie, Suresh C. Srivastava, Brice Kauffmann, and Ivan Huc. “Structure Elucidation of the Pribnow Box Consensus Promoter Sequence by Racemic DNA Crystallography.” Nucleic Acids Research. Oxford University Press, 2016. https://doi.org/10.1093/nar/gkw367. ieee: P. K. Mandal, G. W. Collie, S. C. Srivastava, B. Kauffmann, and I. Huc, “Structure elucidation of the Pribnow box consensus promoter sequence by racemic DNA crystallography,” Nucleic Acids Research, vol. 44, no. 12. Oxford University Press, pp. 5936–5943, 2016. ista: Mandal PK, Collie GW, Srivastava SC, Kauffmann B, Huc I. 2016. Structure elucidation of the Pribnow box consensus promoter sequence by racemic DNA crystallography. Nucleic Acids Research. 44(12), 5936–5943. mla: Mandal, Pradeep K., et al. “Structure Elucidation of the Pribnow Box Consensus Promoter Sequence by Racemic DNA Crystallography.” Nucleic Acids Research, vol. 44, no. 12, Oxford University Press, 2016, pp. 5936–43, doi:10.1093/nar/gkw367. short: P.K. Mandal, G.W. Collie, S.C. Srivastava, B. Kauffmann, I. Huc, Nucleic Acids Research 44 (2016) 5936–5943. date_created: 2026-01-29T21:46:40Z date_published: 2016-07-08T00:00:00Z date_updated: 2026-02-23T09:16:14Z day: '08' ddc: - '570' doi: 10.1093/nar/gkw367 extern: '1' has_accepted_license: '1' intvolume: ' 44' issue: '12' language: - iso: eng license: https://creativecommons.org/licenses/by-nc/4.0/ main_file_link: - open_access: '1' url: https://doi.org/10.1093/nar/gkw367 month: '07' oa: 1 oa_version: Published Version page: 5936-5943 publication: Nucleic Acids Research publication_identifier: eissn: - 1362-4962 issn: - 0305-1048 publication_status: published publisher: Oxford University Press quality_controlled: '1' status: public title: Structure elucidation of the Pribnow box consensus promoter sequence by racemic DNA crystallography tmp: image: /images/cc_by_nc.png legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) short: CC BY-NC (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 44 year: '2016' ... --- _id: '1552' abstract: - lang: eng text: Antibiotic resistance carries a fitness cost that must be overcome in order for resistance to persist over the long term. Compensatory mutations that recover the functional defects associated with resistance mutations have been argued to play a key role in overcoming the cost of resistance, but compensatory mutations are expected to be rare relative to generally beneficial mutations that increase fitness, irrespective of antibiotic resistance. Given this asymmetry, population genetics theory predicts that populations should adapt by compensatory mutations when the cost of resistance is large, whereas generally beneficial mutations should drive adaptation when the cost of resistance is small. We tested this prediction by determining the genomic mechanisms underpinning adaptation to antibiotic-free conditions in populations of the pathogenic bacterium Pseudomonas aeruginosa that carry costly antibiotic resistance mutations. Whole-genome sequencing revealed that populations founded by high-cost rifampicin-resistant mutants adapted via compensatory mutations in three genes of the RNA polymerase core enzyme, whereas populations founded by low-cost mutants adapted by generally beneficial mutations, predominantly in the quorum-sensing transcriptional regulator gene lasR. Even though the importance of compensatory evolution in maintaining resistance has been widely recognized, our study shows that the roles of general adaptation in maintaining resistance should not be underestimated and highlights the need to understand how selection at other sites in the genome influences the dynamics of resistance alleles in clinical settings. acknowledgement: "We thank the High-Throughput Genomics Group at the Wellcome Trust Centre for Human Genetics funded by Wellcome\r\nTrust grant reference 090532/Z/09/Z and Medical Research Council Hub grant no. G0900747 91070 for generation of the high-throughput sequencing data. We thank Wook Kim and two anonymous reviewers for their constructive feedback on previous versions of our manuscript." article_number: '20152452' article_processing_charge: No author: - first_name: Qin full_name: Qi, Qin id: 3B22D412-F248-11E8-B48F-1D18A9856A87 last_name: Qi orcid: 0000-0002-6148-2416 - first_name: Macarena full_name: Toll Riera, Macarena last_name: Toll Riera - first_name: Karl full_name: Heilbron, Karl last_name: Heilbron - first_name: Gail full_name: Preston, Gail last_name: Preston - first_name: R Craig full_name: Maclean, R Craig last_name: Maclean citation: ama: Qi Q, Toll Riera M, Heilbron K, Preston G, Maclean RC. The genomic basis of adaptation to the fitness cost of rifampicin resistance in Pseudomonas aeruginosa. Proceedings of the Royal Society of London Series B Biological Sciences. 2016;283(1822). doi:10.1098/rspb.2015.2452 apa: Qi, Q., Toll Riera, M., Heilbron, K., Preston, G., & Maclean, R. C. (2016). The genomic basis of adaptation to the fitness cost of rifampicin resistance in Pseudomonas aeruginosa. Proceedings of the Royal Society of London Series B Biological Sciences. Royal Society, The. https://doi.org/10.1098/rspb.2015.2452 chicago: Qi, Qin, Macarena Toll Riera, Karl Heilbron, Gail Preston, and R Craig Maclean. “The Genomic Basis of Adaptation to the Fitness Cost of Rifampicin Resistance in Pseudomonas Aeruginosa.” Proceedings of the Royal Society of London Series B Biological Sciences. Royal Society, The, 2016. https://doi.org/10.1098/rspb.2015.2452. ieee: Q. Qi, M. Toll Riera, K. Heilbron, G. Preston, and R. C. Maclean, “The genomic basis of adaptation to the fitness cost of rifampicin resistance in Pseudomonas aeruginosa,” Proceedings of the Royal Society of London Series B Biological Sciences, vol. 283, no. 1822. Royal Society, The, 2016. ista: Qi Q, Toll Riera M, Heilbron K, Preston G, Maclean RC. 2016. The genomic basis of adaptation to the fitness cost of rifampicin resistance in Pseudomonas aeruginosa. Proceedings of the Royal Society of London Series B Biological Sciences. 283(1822), 20152452. mla: Qi, Qin, et al. “The Genomic Basis of Adaptation to the Fitness Cost of Rifampicin Resistance in Pseudomonas Aeruginosa.” Proceedings of the Royal Society of London Series B Biological Sciences, vol. 283, no. 1822, 20152452, Royal Society, The, 2016, doi:10.1098/rspb.2015.2452. short: Q. Qi, M. Toll Riera, K. Heilbron, G. Preston, R.C. Maclean, Proceedings of the Royal Society of London Series B Biological Sciences 283 (2016). date_created: 2018-12-11T11:52:40Z date_published: 2016-01-13T00:00:00Z date_updated: 2025-09-18T11:03:28Z day: '13' ddc: - '570' department: - _id: ToBo doi: 10.1098/rspb.2015.2452 external_id: isi: - '000368441200022' file: - access_level: open_access checksum: 78ffe70c1c88af3856d31ca6b7195a27 content_type: application/pdf creator: system date_created: 2018-12-12T10:11:43Z date_updated: 2020-07-14T12:45:02Z file_id: '4899' file_name: IST-2016-488-v1+1_20152452.full.pdf file_size: 626804 relation: main_file file_date_updated: 2020-07-14T12:45:02Z has_accepted_license: '1' intvolume: ' 283' isi: 1 issue: '1822' language: - iso: eng month: '01' oa: 1 oa_version: Published Version publication: Proceedings of the Royal Society of London Series B Biological Sciences publication_status: published publisher: Royal Society, The publist_id: '5619' pubrep_id: '488' quality_controlled: '1' scopus_import: '1' status: public title: The genomic basis of adaptation to the fitness cost of rifampicin resistance in Pseudomonas aeruginosa tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 283 year: '2016' ... --- _id: '1592' abstract: - lang: eng text: A modular approach to constructing cryptographic protocols leads to simple designs but often inefficient instantiations. On the other hand, ad hoc constructions may yield efficient protocols at the cost of losing conceptual simplicity. We suggest a new design paradigm, structure-preserving cryptography, that provides a way to construct modular protocols with reasonable efficiency while retaining conceptual simplicity. A cryptographic scheme over a bilinear group is called structure-preserving if its public inputs and outputs consist of elements from the bilinear groups and their consistency can be verified by evaluating pairing-product equations. As structure-preserving schemes smoothly interoperate with each other, they are useful as building blocks in modular design of cryptographic applications. This paper introduces structure-preserving commitment and signature schemes over bilinear groups with several desirable properties. The commitment schemes include homomorphic, trapdoor and length-reducing commitments to group elements, and the structure-preserving signature schemes are the first ones that yield constant-size signatures on multiple group elements. A structure-preserving signature scheme is called automorphic if the public keys lie in the message space, which cannot be achieved by compressing inputs via a cryptographic hash function, as this would destroy the mathematical structure we are trying to preserve. Automorphic signatures can be used for building certification chains underlying privacy-preserving protocols. Among a vast number of applications of structure-preserving protocols, we present an efficient round-optimal blind-signature scheme and a group signature scheme with an efficient and concurrently secure protocol for enrolling new members. acknowledgement: The authors would like to thank the anonymous reviewers of this paper. We also would like to express our appreciation to the program committee and the anonymous reviewers for CRYPTO 2010. The first author thanks Sherman S. M. Chow for his comment on group signatures in Sect. 7.1. article_processing_charge: No author: - first_name: Masayuki full_name: Abe, Masayuki last_name: Abe - first_name: Georg full_name: Fuchsbauer, Georg id: 46B4C3EE-F248-11E8-B48F-1D18A9856A87 last_name: Fuchsbauer - first_name: Jens full_name: Groth, Jens last_name: Groth - first_name: Kristiyan full_name: Haralambiev, Kristiyan last_name: Haralambiev - first_name: Miyako full_name: Ohkubo, Miyako last_name: Ohkubo citation: ama: Abe M, Fuchsbauer G, Groth J, Haralambiev K, Ohkubo M. Structure preserving signatures and commitments to group elements. Journal of Cryptology. 2016;29(2):363-421. doi:10.1007/s00145-014-9196-7 apa: Abe, M., Fuchsbauer, G., Groth, J., Haralambiev, K., & Ohkubo, M. (2016). Structure preserving signatures and commitments to group elements. Journal of Cryptology. Springer. https://doi.org/10.1007/s00145-014-9196-7 chicago: Abe, Masayuki, Georg Fuchsbauer, Jens Groth, Kristiyan Haralambiev, and Miyako Ohkubo. “Structure Preserving Signatures and Commitments to Group Elements.” Journal of Cryptology. Springer, 2016. https://doi.org/10.1007/s00145-014-9196-7. ieee: M. Abe, G. Fuchsbauer, J. Groth, K. Haralambiev, and M. Ohkubo, “Structure preserving signatures and commitments to group elements,” Journal of Cryptology, vol. 29, no. 2. Springer, pp. 363–421, 2016. ista: Abe M, Fuchsbauer G, Groth J, Haralambiev K, Ohkubo M. 2016. Structure preserving signatures and commitments to group elements. Journal of Cryptology. 29(2), 363–421. mla: Abe, Masayuki, et al. “Structure Preserving Signatures and Commitments to Group Elements.” Journal of Cryptology, vol. 29, no. 2, Springer, 2016, pp. 363–421, doi:10.1007/s00145-014-9196-7. short: M. Abe, G. Fuchsbauer, J. Groth, K. Haralambiev, M. Ohkubo, Journal of Cryptology 29 (2016) 363–421. date_created: 2018-12-11T11:52:54Z date_published: 2016-04-01T00:00:00Z date_updated: 2025-09-18T11:02:49Z day: '01' department: - _id: KrPi doi: 10.1007/s00145-014-9196-7 external_id: isi: - '000371077900004' intvolume: ' 29' isi: 1 issue: '2' language: - iso: eng month: '04' oa_version: None page: 363 - 421 publication: Journal of Cryptology publication_status: published publisher: Springer publist_id: '5579' quality_controlled: '1' scopus_import: '1' status: public title: Structure preserving signatures and commitments to group elements type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 29 year: '2016' ... --- _id: '1597' abstract: - lang: eng text: Chemokines are the main guidance cues directing leukocyte migration. Opposed to early assumptions, chemokines do not necessarily act as soluble cues but are often immobilized within tissues, e.g., dendritic cell migration toward lymphatic vessels is guided by a haptotactic gradient of the chemokine CCL21. Controlled assay systems to quantitatively study haptotaxis in vitro are still missing. In this chapter, we describe an in vitro haptotaxis assay optimized for the unique properties of dendritic cells. The chemokine CCL21 is immobilized in a bioactive state, using laser-assisted protein adsorption by photobleaching. The cells follow this immobilized CCL21 gradient in a haptotaxis chamber, which provides three dimensionally confined migration conditions. acknowledged_ssus: - _id: Bio acknowledgement: This work was supported by the Boehringer Ingelheim Fonds, the European Research Council (ERC StG 281556), and a START Award of the Austrian Science Foundation (FWF). We thank Robert Hauschild, Anne Reversat, and Jack Merrin for valuable input and the Imaging Facility of IST Austria for excellent support. article_processing_charge: No article_type: original author: - first_name: Jan full_name: Schwarz, Jan id: 346C1EC6-F248-11E8-B48F-1D18A9856A87 last_name: Schwarz - first_name: Michael K full_name: Sixt, Michael K id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87 last_name: Sixt orcid: 0000-0002-6620-9179 citation: ama: Schwarz J, Sixt MK. Quantitative analysis of dendritic cell haptotaxis. Methods in Enzymology. 2016;570:567-581. doi:10.1016/bs.mie.2015.11.004 apa: Schwarz, J., & Sixt, M. K. (2016). Quantitative analysis of dendritic cell haptotaxis. Methods in Enzymology. Elsevier. https://doi.org/10.1016/bs.mie.2015.11.004 chicago: Schwarz, Jan, and Michael K Sixt. “Quantitative Analysis of Dendritic Cell Haptotaxis.” Methods in Enzymology. Elsevier, 2016. https://doi.org/10.1016/bs.mie.2015.11.004. ieee: J. Schwarz and M. K. Sixt, “Quantitative analysis of dendritic cell haptotaxis,” Methods in Enzymology, vol. 570. Elsevier, pp. 567–581, 2016. ista: Schwarz J, Sixt MK. 2016. Quantitative analysis of dendritic cell haptotaxis. Methods in Enzymology. 570, 567–581. mla: Schwarz, Jan, and Michael K. Sixt. “Quantitative Analysis of Dendritic Cell Haptotaxis.” Methods in Enzymology, vol. 570, Elsevier, 2016, pp. 567–81, doi:10.1016/bs.mie.2015.11.004. short: J. Schwarz, M.K. Sixt, Methods in Enzymology 570 (2016) 567–581. corr_author: '1' date_created: 2018-12-11T11:52:56Z date_published: 2016-01-01T00:00:00Z date_updated: 2025-09-18T11:02:13Z day: '01' department: - _id: MiSi doi: 10.1016/bs.mie.2015.11.004 ec_funded: 1 external_id: isi: - '000375648700025' pmid: - '26921962' intvolume: ' 570' isi: 1 language: - iso: eng month: '01' oa_version: None page: 567 - 581 pmid: 1 project: - _id: 25A603A2-B435-11E9-9278-68D0E5697425 call_identifier: FP7 grant_number: '281556' name: Cytoskeletal force generation and force transduction of migrating leukocytes - _id: 25A8E5EA-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: Y 564-B12 name: Cytoskeletal force generation and force transduction of migrating leukocytes publication: Methods in Enzymology publication_status: published publisher: Elsevier publist_id: '5573' quality_controlled: '1' scopus_import: '1' status: public title: Quantitative analysis of dendritic cell haptotaxis type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 570 year: '2016' ... --- _id: '1599' abstract: - lang: eng text: "The addition of polysialic acid to N- and/or O-linked glycans, referred to as polysialylation, is a rare posttranslational modification that is mainly known to control the developmental plasticity of the nervous system. Here we show that CCR7, the central chemokine receptor controlling immune cell trafficking to secondary lymphatic organs, carries polysialic acid. This modification is essential for the recognition of the CCR7 ligand CCL21. As a consequence, dendritic cell trafficking is abrogated in polysialyltransferase-deficient mice, manifesting as disturbed lymph node homeostasis and unresponsiveness to inflammatory stimuli. Structure-function analysis of chemokine-receptor interactions reveals that CCL21 adopts an autoinhibited conformation, which is released upon interaction with polysialic acid. Thus, we describe a glycosylation-mediated immune cell trafficking disorder and its mechanistic basis.\r\n" acknowledged_ssus: - _id: SSU acknowledgement: 'We thank S. Schüchner and E. Ogris for kindly providing the antibody to GFP, M. Helmbrecht and A. Huber for providing Nrp2−/− mice, the IST Scientific Support Facilities for excellent services, and J. Renkawitz and K. Vaahtomeri for critically reading the manuscript. ' article_processing_charge: No article_type: original author: - first_name: Eva full_name: Kiermaier, Eva id: 3EB04B78-F248-11E8-B48F-1D18A9856A87 last_name: Kiermaier orcid: 0000-0001-6165-5738 - first_name: Christine full_name: Moussion, Christine id: 3356F664-F248-11E8-B48F-1D18A9856A87 last_name: Moussion - first_name: Christopher full_name: Veldkamp, Christopher last_name: Veldkamp - first_name: Rita full_name: Gerardy Schahn, Rita last_name: Gerardy Schahn - first_name: Ingrid full_name: De Vries, Ingrid id: 4C7D837E-F248-11E8-B48F-1D18A9856A87 last_name: De Vries - first_name: Larry full_name: Williams, Larry last_name: Williams - first_name: Gary full_name: Chaffee, Gary last_name: Chaffee - first_name: Andrew full_name: Phillips, Andrew last_name: Phillips - first_name: Friedrich full_name: Freiberger, Friedrich last_name: Freiberger - first_name: Richard full_name: Imre, Richard last_name: Imre - first_name: Deni full_name: Taleski, Deni last_name: Taleski - first_name: Richard full_name: Payne, Richard last_name: Payne - first_name: Asolina full_name: Braun, Asolina last_name: Braun - first_name: Reinhold full_name: Förster, Reinhold last_name: Förster - first_name: Karl full_name: Mechtler, Karl last_name: Mechtler - first_name: Martina full_name: Mühlenhoff, Martina last_name: Mühlenhoff - first_name: Brian full_name: Volkman, Brian last_name: Volkman - first_name: Michael K full_name: Sixt, Michael K id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87 last_name: Sixt orcid: 0000-0002-6620-9179 citation: ama: Kiermaier E, Moussion C, Veldkamp C, et al. Polysialylation controls dendritic cell trafficking by regulating chemokine recognition. Science. 2016;351(6269):186-190. doi:10.1126/science.aad0512 apa: Kiermaier, E., Moussion, C., Veldkamp, C., Gerardy  Schahn, R., de Vries, I., Williams, L., … Sixt, M. K. (2016). Polysialylation controls dendritic cell trafficking by regulating chemokine recognition. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.aad0512 chicago: Kiermaier, Eva, Christine Moussion, Christopher Veldkamp, Rita Gerardy  Schahn, Ingrid de Vries, Larry Williams, Gary Chaffee, et al. “Polysialylation Controls Dendritic Cell Trafficking by Regulating Chemokine Recognition.” Science. American Association for the Advancement of Science, 2016. https://doi.org/10.1126/science.aad0512. ieee: E. Kiermaier et al., “Polysialylation controls dendritic cell trafficking by regulating chemokine recognition,” Science, vol. 351, no. 6269. American Association for the Advancement of Science, pp. 186–190, 2016. ista: Kiermaier E, Moussion C, Veldkamp C, Gerardy  Schahn R, de Vries I, Williams L, Chaffee G, Phillips A, Freiberger F, Imre R, Taleski D, Payne R, Braun A, Förster R, Mechtler K, Mühlenhoff M, Volkman B, Sixt MK. 2016. Polysialylation controls dendritic cell trafficking by regulating chemokine recognition. Science. 351(6269), 186–190. mla: Kiermaier, Eva, et al. “Polysialylation Controls Dendritic Cell Trafficking by Regulating Chemokine Recognition.” Science, vol. 351, no. 6269, American Association for the Advancement of Science, 2016, pp. 186–90, doi:10.1126/science.aad0512. short: E. Kiermaier, C. Moussion, C. Veldkamp, R. Gerardy  Schahn, I. de Vries, L. Williams, G. Chaffee, A. Phillips, F. Freiberger, R. Imre, D. Taleski, R. Payne, A. Braun, R. Förster, K. Mechtler, M. Mühlenhoff, B. Volkman, M.K. Sixt, Science 351 (2016) 186–190. corr_author: '1' date_created: 2018-12-11T11:52:57Z date_published: 2016-01-08T00:00:00Z date_updated: 2025-09-18T11:01:30Z day: '08' department: - _id: MiSi doi: 10.1126/science.aad0512 ec_funded: 1 external_id: isi: - '000367806500045' pmid: - '26657283' intvolume: ' 351' isi: 1 issue: '6269' language: - iso: eng main_file_link: - open_access: '1' url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583642/ month: '01' oa: 1 oa_version: Submitted Version page: 186 - 190 pmid: 1 project: - _id: 25A603A2-B435-11E9-9278-68D0E5697425 call_identifier: FP7 grant_number: '281556' name: Cytoskeletal force generation and force transduction of migrating leukocytes - _id: 25A76F58-B435-11E9-9278-68D0E5697425 call_identifier: FP7 grant_number: '289720' name: Stromal Cell-immune Cell Interactions in Health and Disease - _id: 25A8E5EA-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: Y 564-B12 name: Cytoskeletal force generation and force transduction of migrating leukocytes publication: Science publication_status: published publisher: American Association for the Advancement of Science publist_id: '5570' quality_controlled: '1' scopus_import: '1' status: public title: Polysialylation controls dendritic cell trafficking by regulating chemokine recognition type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 351 year: '2016' ... --- _id: '1608' abstract: - lang: eng text: 'We show that the Anderson model has a transition from localization to delocalization at exactly 2 dimensional growth rate on antitrees with normalized edge weights which are certain discrete graphs. The kinetic part has a one-dimensional structure allowing a description through transfer matrices which involve some Schur complement. For such operators we introduce the notion of having one propagating channel and extend theorems from the theory of one-dimensional Jacobi operators that relate the behavior of transfer matrices with the spectrum. These theorems are then applied to the considered model. In essence, in a certain energy region the kinetic part averages the random potentials along shells and the transfer matrices behave similar as for a one-dimensional operator with random potential of decaying variance. At d dimensional growth for d>2 this effective decay is strong enough to obtain absolutely continuous spectrum, whereas for some uniform d dimensional growth with d<2 one has pure point spectrum in this energy region. At exactly uniform 2 dimensional growth also some singular continuous spectrum appears, at least at small disorder. As a corollary we also obtain a change from singular spectrum (d≤2) to absolutely continuous spectrum (d≥3) for random operators of the type rΔdr+λ on ℤd, where r is an orthogonal radial projection, Δd the discrete adjacency operator (Laplacian) on ℤd and λ a random potential. ' article_processing_charge: No arxiv: 1 author: - first_name: Christian full_name: Sadel, Christian id: 4760E9F8-F248-11E8-B48F-1D18A9856A87 last_name: Sadel orcid: 0000-0001-8255-3968 citation: ama: Sadel C. Anderson transition at 2 dimensional growth rate on antitrees and spectral theory for operators with one propagating channel. Annales Henri Poincare. 2016;17(7):1631-1675. doi:10.1007/s00023-015-0456-3 apa: Sadel, C. (2016). Anderson transition at 2 dimensional growth rate on antitrees and spectral theory for operators with one propagating channel. Annales Henri Poincare. Birkhäuser. https://doi.org/10.1007/s00023-015-0456-3 chicago: Sadel, Christian. “Anderson Transition at 2 Dimensional Growth Rate on Antitrees and Spectral Theory for Operators with One Propagating Channel.” Annales Henri Poincare. Birkhäuser, 2016. https://doi.org/10.1007/s00023-015-0456-3. ieee: C. Sadel, “Anderson transition at 2 dimensional growth rate on antitrees and spectral theory for operators with one propagating channel,” Annales Henri Poincare, vol. 17, no. 7. Birkhäuser, pp. 1631–1675, 2016. ista: Sadel C. 2016. Anderson transition at 2 dimensional growth rate on antitrees and spectral theory for operators with one propagating channel. Annales Henri Poincare. 17(7), 1631–1675. mla: Sadel, Christian. “Anderson Transition at 2 Dimensional Growth Rate on Antitrees and Spectral Theory for Operators with One Propagating Channel.” Annales Henri Poincare, vol. 17, no. 7, Birkhäuser, 2016, pp. 1631–75, doi:10.1007/s00023-015-0456-3. short: C. Sadel, Annales Henri Poincare 17 (2016) 1631–1675. corr_author: '1' date_created: 2018-12-11T11:53:00Z date_published: 2016-07-01T00:00:00Z date_updated: 2025-09-18T11:00:43Z day: '01' department: - _id: LaEr doi: 10.1007/s00023-015-0456-3 ec_funded: 1 external_id: arxiv: - '1501.04287' isi: - '000377994000003' intvolume: ' 17' isi: 1 issue: '7' language: - iso: eng main_file_link: - open_access: '1' url: http://arxiv.org/abs/1501.04287 month: '07' oa: 1 oa_version: Preprint page: 1631 - 1675 project: - _id: 25681D80-B435-11E9-9278-68D0E5697425 call_identifier: FP7 grant_number: '291734' name: International IST Postdoc Fellowship Programme publication: Annales Henri Poincare publication_status: published publisher: Birkhäuser publist_id: '5558' quality_controlled: '1' scopus_import: '1' status: public title: Anderson transition at 2 dimensional growth rate on antitrees and spectral theory for operators with one propagating channel type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 17 year: '2016' ... --- _id: '1612' abstract: - lang: eng text: We prove that whenever A is a 3-conservative relational structure with only binary and unary relations,then the algebra of polymorphisms of A either has no Taylor operation (i.e.,CSP(A)is NP-complete),or it generates an SD(∧) variety (i.e.,CSP(A)has bounded width). article_processing_charge: No arxiv: 1 author: - first_name: Alexandr full_name: Kazda, Alexandr id: 3B32BAA8-F248-11E8-B48F-1D18A9856A87 last_name: Kazda citation: ama: Kazda A. CSP for binary conservative relational structures. Algebra Universalis. 2016;75(1):75-84. doi:10.1007/s00012-015-0358-8 apa: Kazda, A. (2016). CSP for binary conservative relational structures. Algebra Universalis. Springer. https://doi.org/10.1007/s00012-015-0358-8 chicago: Kazda, Alexandr. “CSP for Binary Conservative Relational Structures.” Algebra Universalis. Springer, 2016. https://doi.org/10.1007/s00012-015-0358-8. ieee: A. Kazda, “CSP for binary conservative relational structures,” Algebra Universalis, vol. 75, no. 1. Springer, pp. 75–84, 2016. ista: Kazda A. 2016. CSP for binary conservative relational structures. Algebra Universalis. 75(1), 75–84. mla: Kazda, Alexandr. “CSP for Binary Conservative Relational Structures.” Algebra Universalis, vol. 75, no. 1, Springer, 2016, pp. 75–84, doi:10.1007/s00012-015-0358-8. short: A. Kazda, Algebra Universalis 75 (2016) 75–84. corr_author: '1' date_created: 2018-12-11T11:53:01Z date_published: 2016-02-01T00:00:00Z date_updated: 2025-09-18T11:00:04Z day: '01' department: - _id: VlKo doi: 10.1007/s00012-015-0358-8 external_id: arxiv: - '1112.1099' isi: - '000375422500006' intvolume: ' 75' isi: 1 issue: '1' language: - iso: eng main_file_link: - open_access: '1' url: http://arxiv.org/abs/1112.1099 month: '02' oa: 1 oa_version: Preprint page: 75 - 84 publication: Algebra Universalis publication_status: published publisher: Springer publist_id: '5554' quality_controlled: '1' scopus_import: '1' status: public title: CSP for binary conservative relational structures type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 75 year: '2016' ... --- _id: '1613' abstract: - lang: eng text: "In the last decade, induced pluripotent stem (iPS) cells have revolutionized the utility of human in vitro models of neurological disease. The iPS-derived and differentiated cells allow researchers to study the impact of a distinct cell type in health and disease as well as performing therapeutic drug screens on a human genetic background. In particular, clinical trials for Alzheimer's disease (AD) have been often failing. Two of the potential reasons are first, the species gap involved in proceeding from initial discoveries in rodent models to human studies, and second, an unsatisfying patient stratification, meaning subgrouping patients based on the disease severity due to the lack of phenotypic and genetic markers. iPS cells overcome this obstacles and will improve our understanding of disease subtypes in AD. They allow researchers conducting in depth characterization of neural cells from both familial and sporadic AD patients as well as preclinical screens on human cells.\r\n\r\nIn this review, we briefly outline the status quo of iPS cell research in neurological diseases along with the general advantages and pitfalls of these models. We summarize how genome-editing techniques such as CRISPR/Cas will allow researchers to reduce the problem of genomic variability inherent to human studies, followed by recent iPS cell studies relevant to AD. We then focus on current techniques for the differentiation of iPS cells into neural cell types that are relevant to AD research. Finally, we discuss how the generation of three-dimensional cell culture systems will be important for understanding AD phenotypes in a complex cellular milieu, and how both two- and three-dimensional iPS cell models can provide platforms for drug discovery and translational studies into the treatment of AD." acknowledgement: This work was supported by NIH grant R01-AG047661 to LHT. The art in Fig. 1 was created by Julian Wong. article_processing_charge: No author: - first_name: Alison full_name: Mungenast, Alison last_name: Mungenast - first_name: Sandra full_name: Siegert, Sandra id: 36ACD32E-F248-11E8-B48F-1D18A9856A87 last_name: Siegert orcid: 0000-0001-8635-0877 - first_name: Li full_name: Tsai, Li last_name: Tsai citation: ama: Mungenast A, Siegert S, Tsai L. Modeling Alzheimer’s disease with human induced pluripotent stem (iPS) cells. Molecular and Cellular Neuroscience. 2016;73:13-31. doi:doi:10.1016/j.mcn.2015.11.010 apa: Mungenast, A., Siegert, S., & Tsai, L. (2016). Modeling Alzheimer’s disease with human induced pluripotent stem (iPS) cells. Molecular and Cellular Neuroscience. Academic Press. https://doi.org/doi:10.1016/j.mcn.2015.11.010 chicago: Mungenast, Alison, Sandra Siegert, and Li Tsai. “Modeling Alzheimer’s Disease with Human Induced Pluripotent Stem (IPS) Cells.” Molecular and Cellular Neuroscience. Academic Press, 2016. https://doi.org/doi:10.1016/j.mcn.2015.11.010. ieee: A. Mungenast, S. Siegert, and L. Tsai, “Modeling Alzheimer’s disease with human induced pluripotent stem (iPS) cells,” Molecular and Cellular Neuroscience, vol. 73. Academic Press, pp. 13–31, 2016. ista: Mungenast A, Siegert S, Tsai L. 2016. Modeling Alzheimer’s disease with human induced pluripotent stem (iPS) cells. Molecular and Cellular Neuroscience. 73, 13–31. mla: Mungenast, Alison, et al. “Modeling Alzheimer’s Disease with Human Induced Pluripotent Stem (IPS) Cells.” Molecular and Cellular Neuroscience, vol. 73, Academic Press, 2016, pp. 13–31, doi:doi:10.1016/j.mcn.2015.11.010. short: A. Mungenast, S. Siegert, L. Tsai, Molecular and Cellular Neuroscience 73 (2016) 13–31. corr_author: '1' date_created: 2018-12-11T11:53:02Z date_published: 2016-06-01T00:00:00Z date_updated: 2025-09-18T10:59:24Z day: '01' ddc: - '616' doi: doi:10.1016/j.mcn.2015.11.010 extern: '1' external_id: isi: - '000376225300003' file: - access_level: open_access checksum: 620254114e04d5d6e7f37d15e4b8ace4 content_type: application/pdf creator: system date_created: 2018-12-12T10:12:50Z date_updated: 2020-07-14T12:45:07Z file_id: '4970' file_name: IST-2018-979-v1+1_Mungenast_2015_acceptedManuscript.pdf file_size: 632915 relation: main_file file_date_updated: 2020-07-14T12:45:07Z has_accepted_license: '1' intvolume: ' 73' isi: 1 language: - iso: eng month: '06' oa: 1 oa_version: Submitted Version page: 13 - 31 publication: Molecular and Cellular Neuroscience publication_status: published publisher: Academic Press publist_id: '5553' pubrep_id: '979' quality_controlled: '1' status: public title: Modeling Alzheimer's disease with human induced pluripotent stem (iPS) cells tmp: image: /images/cc_by_nc_nd.png legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) short: CC BY-NC-ND (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 73 year: '2016' ... --- _id: '1616' abstract: - lang: eng text: The hippocampus plays a key role in learning and memory. Previous studies suggested that the main types of principal neurons, dentate gyrus granule cells (GCs), CA3 pyramidal neurons, and CA1 pyramidal neurons, differ in their activity pattern, with sparse firing in GCs and more frequent firing in CA3 and CA1 pyramidal neurons. It has been assumed but never shown that such different activity may be caused by differential synaptic excitation. To test this hypothesis, we performed high-resolution whole-cell patch-clamp recordings in anesthetized rats in vivo. In contrast to previous in vitro data, both CA3 and CA1 pyramidal neurons fired action potentials spontaneously, with a frequency of ∼3–6 Hz, whereas GCs were silent. Furthermore, both CA3 and CA1 cells primarily fired in bursts. To determine the underlying mechanisms, we quantitatively assessed the frequency of spontaneous excitatory synaptic input, the passive membrane properties, and the active membrane characteristics. Surprisingly, GCs showed comparable synaptic excitation to CA3 and CA1 cells and the highest ratio of excitation versus hyperpolarizing inhibition. Thus, differential synaptic excitation is not responsible for differences in firing. Moreover, the three types of hippocampal neurons markedly differed in their passive properties. While GCs showed the most negative membrane potential, CA3 pyramidal neurons had the highest input resistance and the slowest membrane time constant. The three types of neurons also differed in the active membrane characteristics. GCs showed the highest action potential threshold, but displayed the largest gain of the input-output curves. In conclusion, our results reveal that differential firing of the three main types of hippocampal principal neurons in vivo is not primarily caused by differences in the characteristics of the synaptic input, but by the distinct properties of synaptic integration and input-output transformation. acknowledgement: "The authors thank Jose Guzman for critically reading prior versions of the manuscript. They also thank T. Asenov for\r\nengineering mechanical devices, A. Schlögl for efficient pro-gramming, F. Marr for technical assistance, and E. Kramberger for manuscript editing." article_processing_charge: No author: - first_name: Janina full_name: Kowalski, Janina id: 3F3CA136-F248-11E8-B48F-1D18A9856A87 last_name: Kowalski - first_name: Jian full_name: Gan, Jian id: 3614E438-F248-11E8-B48F-1D18A9856A87 last_name: Gan - first_name: Peter M full_name: Jonas, Peter M id: 353C1B58-F248-11E8-B48F-1D18A9856A87 last_name: Jonas orcid: 0000-0001-5001-4804 - first_name: Alejandro full_name: Pernia-Andrade, Alejandro id: 36963E98-F248-11E8-B48F-1D18A9856A87 last_name: Pernia-Andrade citation: ama: Kowalski J, Gan J, Jonas PM, Pernia-Andrade A. Intrinsic membrane properties determine hippocampal differential firing pattern in vivo in anesthetized rats. Hippocampus. 2016;26(5):668-682. doi:10.1002/hipo.22550 apa: Kowalski, J., Gan, J., Jonas, P. M., & Pernia-Andrade, A. (2016). Intrinsic membrane properties determine hippocampal differential firing pattern in vivo in anesthetized rats. Hippocampus. Wiley. https://doi.org/10.1002/hipo.22550 chicago: Kowalski, Janina, Jian Gan, Peter M Jonas, and Alejandro Pernia-Andrade. “Intrinsic Membrane Properties Determine Hippocampal Differential Firing Pattern in Vivo in Anesthetized Rats.” Hippocampus. Wiley, 2016. https://doi.org/10.1002/hipo.22550. ieee: J. Kowalski, J. Gan, P. M. Jonas, and A. Pernia-Andrade, “Intrinsic membrane properties determine hippocampal differential firing pattern in vivo in anesthetized rats,” Hippocampus, vol. 26, no. 5. Wiley, pp. 668–682, 2016. ista: Kowalski J, Gan J, Jonas PM, Pernia-Andrade A. 2016. Intrinsic membrane properties determine hippocampal differential firing pattern in vivo in anesthetized rats. Hippocampus. 26(5), 668–682. mla: Kowalski, Janina, et al. “Intrinsic Membrane Properties Determine Hippocampal Differential Firing Pattern in Vivo in Anesthetized Rats.” Hippocampus, vol. 26, no. 5, Wiley, 2016, pp. 668–82, doi:10.1002/hipo.22550. short: J. Kowalski, J. Gan, P.M. Jonas, A. Pernia-Andrade, Hippocampus 26 (2016) 668–682. corr_author: '1' date_created: 2018-12-11T11:53:03Z date_published: 2016-05-01T00:00:00Z date_updated: 2025-09-18T10:58:31Z day: '01' ddc: - '570' department: - _id: PeJo doi: 10.1002/hipo.22550 external_id: isi: - '000374666700011' file: - access_level: open_access checksum: 284b72b12fbe15474833ed3d4549f86b content_type: application/pdf creator: system date_created: 2018-12-12T10:13:47Z date_updated: 2020-07-14T12:45:07Z file_id: '5033' file_name: IST-2016-469-v1+1_Kowalski_et_al-Hippocampus.pdf file_size: 905348 relation: main_file file_date_updated: 2020-07-14T12:45:07Z has_accepted_license: '1' intvolume: ' 26' isi: 1 issue: '5' language: - iso: eng month: '05' oa: 1 oa_version: Published Version page: 668 - 682 publication: Hippocampus publication_identifier: eissn: - 1098-1063 issn: - 1050-9631 publication_status: published publisher: Wiley publist_id: '5550' pubrep_id: '469' quality_controlled: '1' scopus_import: '1' status: public title: Intrinsic membrane properties determine hippocampal differential firing pattern in vivo in anesthetized rats tmp: image: /images/cc_by_nc_nd.png legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) short: CC BY-NC-ND (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 26 year: '2016' ... --- _id: '1617' abstract: - lang: eng text: 'We study the discrepancy of jittered sampling sets: such a set P⊂ [0,1]d is generated for fixed m∈ℕ by partitioning [0,1]d into md axis aligned cubes of equal measure and placing a random point inside each of the N=md cubes. We prove that, for N sufficiently large, 1/10 d/N1/2+1/2d ≤EDN∗(P)≤ √d(log N) 1/2/N1/2+1/2d, where the upper bound with an unspecified constant Cd was proven earlier by Beck. Our proof makes crucial use of the sharp Dvoretzky-Kiefer-Wolfowitz inequality and a suitably taylored Bernstein inequality; we have reasons to believe that the upper bound has the sharp scaling in N. Additional heuristics suggest that jittered sampling should be able to improve known bounds on the inverse of the star-discrepancy in the regime N≳dd. We also prove a partition principle showing that every partition of [0,1]d combined with a jittered sampling construction gives rise to a set whose expected squared L2-discrepancy is smaller than that of purely random points.' acknowledgement: We are grateful to the referee whose suggestions greatly improved the quality and clarity of the exposition. article_processing_charge: No arxiv: 1 author: - first_name: Florian full_name: Pausinger, Florian id: 2A77D7A2-F248-11E8-B48F-1D18A9856A87 last_name: Pausinger orcid: 0000-0002-8379-3768 - first_name: Stefan full_name: Steinerberger, Stefan last_name: Steinerberger citation: ama: Pausinger F, Steinerberger S. On the discrepancy of jittered sampling. Journal of Complexity. 2016;33:199-216. doi:10.1016/j.jco.2015.11.003 apa: Pausinger, F., & Steinerberger, S. (2016). On the discrepancy of jittered sampling. Journal of Complexity. Academic Press. https://doi.org/10.1016/j.jco.2015.11.003 chicago: Pausinger, Florian, and Stefan Steinerberger. “On the Discrepancy of Jittered Sampling.” Journal of Complexity. Academic Press, 2016. https://doi.org/10.1016/j.jco.2015.11.003. ieee: F. Pausinger and S. Steinerberger, “On the discrepancy of jittered sampling,” Journal of Complexity, vol. 33. Academic Press, pp. 199–216, 2016. ista: Pausinger F, Steinerberger S. 2016. On the discrepancy of jittered sampling. Journal of Complexity. 33, 199–216. mla: Pausinger, Florian, and Stefan Steinerberger. “On the Discrepancy of Jittered Sampling.” Journal of Complexity, vol. 33, Academic Press, 2016, pp. 199–216, doi:10.1016/j.jco.2015.11.003. short: F. Pausinger, S. Steinerberger, Journal of Complexity 33 (2016) 199–216. date_created: 2018-12-11T11:53:03Z date_published: 2016-04-01T00:00:00Z date_updated: 2025-09-18T10:57:52Z day: '01' department: - _id: HeEd doi: 10.1016/j.jco.2015.11.003 external_id: arxiv: - '1510.00251' isi: - '000370090400011' intvolume: ' 33' isi: 1 language: - iso: eng main_file_link: - open_access: '1' url: http://arxiv.org/abs/1510.00251 month: '04' oa: 1 oa_version: Submitted Version page: 199 - 216 publication: Journal of Complexity publication_status: published publisher: Academic Press publist_id: '5549' quality_controlled: '1' scopus_import: '1' status: public title: On the discrepancy of jittered sampling type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 33 year: '2016' ... --- _id: '1620' abstract: - lang: eng text: We consider the Bardeen–Cooper–Schrieffer free energy functional for particles interacting via a two-body potential on a microscopic scale and in the presence of weak external fields varying on a macroscopic scale. We study the influence of the external fields on the critical temperature. We show that in the limit where the ratio between the microscopic and macroscopic scale tends to zero, the next to leading order of the critical temperature is determined by the lowest eigenvalue of the linearization of the Ginzburg–Landau equation. acknowledgement: The authors are grateful to I. M. Sigal for useful discussions. Financial support from the US National Science Foundation through Grants PHY-1347399 and DMS-1363432 (R.L.F.), from the Danish council for independent research and from ERC Advanced Grant 321029 (J.P.S.) is acknowledged. article_processing_charge: No arxiv: 1 author: - first_name: Rupert full_name: Frank, Rupert last_name: Frank - first_name: Christian full_name: Hainzl, Christian last_name: Hainzl - first_name: Robert full_name: Seiringer, Robert id: 4AFD0470-F248-11E8-B48F-1D18A9856A87 last_name: Seiringer orcid: 0000-0002-6781-0521 - first_name: Jan full_name: Solovej, Jan last_name: Solovej citation: ama: Frank R, Hainzl C, Seiringer R, Solovej J. The external field dependence of the BCS critical temperature. Communications in Mathematical Physics. 2016;342(1):189-216. doi:10.1007/s00220-015-2526-2 apa: Frank, R., Hainzl, C., Seiringer, R., & Solovej, J. (2016). The external field dependence of the BCS critical temperature. Communications in Mathematical Physics. Springer. https://doi.org/10.1007/s00220-015-2526-2 chicago: Frank, Rupert, Christian Hainzl, Robert Seiringer, and Jan Solovej. “The External Field Dependence of the BCS Critical Temperature.” Communications in Mathematical Physics. Springer, 2016. https://doi.org/10.1007/s00220-015-2526-2. ieee: R. Frank, C. Hainzl, R. Seiringer, and J. Solovej, “The external field dependence of the BCS critical temperature,” Communications in Mathematical Physics, vol. 342, no. 1. Springer, pp. 189–216, 2016. ista: Frank R, Hainzl C, Seiringer R, Solovej J. 2016. The external field dependence of the BCS critical temperature. Communications in Mathematical Physics. 342(1), 189–216. mla: Frank, Rupert, et al. “The External Field Dependence of the BCS Critical Temperature.” Communications in Mathematical Physics, vol. 342, no. 1, Springer, 2016, pp. 189–216, doi:10.1007/s00220-015-2526-2. short: R. Frank, C. Hainzl, R. Seiringer, J. Solovej, Communications in Mathematical Physics 342 (2016) 189–216. date_created: 2018-12-11T11:53:04Z date_published: 2016-02-01T00:00:00Z date_updated: 2025-09-18T10:57:14Z day: '01' department: - _id: RoSe doi: 10.1007/s00220-015-2526-2 external_id: arxiv: - '1410.2352' isi: - '000369965600006' intvolume: ' 342' isi: 1 issue: '1' language: - iso: eng main_file_link: - open_access: '1' url: http://arxiv.org/abs/1410.2352 month: '02' oa: 1 oa_version: Submitted Version page: 189 - 216 publication: Communications in Mathematical Physics publication_status: published publisher: Springer publist_id: '5546' quality_controlled: '1' scopus_import: '1' status: public title: The external field dependence of the BCS critical temperature type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 342 year: '2016' ... --- _id: '1622' abstract: - lang: eng text: We prove analogues of the Lieb–Thirring and Hardy–Lieb–Thirring inequalities for many-body quantum systems with fractional kinetic operators and homogeneous interaction potentials, where no anti-symmetry on the wave functions is assumed. These many-body inequalities imply interesting one-body interpolation inequalities, and we show that the corresponding one- and many-body inequalities are actually equivalent in certain cases. acknowledgement: "We thank Jan Philip Solovej, Robert Seiringer and Vladimir Maz’ya for helpful discussions, as well as Rupert Frank\r\nand the anonymous referee for useful comments. Part of this work has been carried out during a visit at the Institut Mittag-Leffler (Stockholm). D.L. acknowledges financial support by the grant KAW 2010.0063 from the Knut and Alice Wallenberg Foundation and the Swedish Research Council grant no. 2013-4734. P.T.N. is supported by the People Programme (Marie Curie Actions) of the European Union’s Seventh Framework Programme (FP7/2007-2013) under REA grant agreement no. 291734. F.P. acknowledges support from the ERC project no. 321029 “The\r\nmathematics of the structure of matter”." article_processing_charge: No arxiv: 1 author: - first_name: Douglas full_name: Lundholm, Douglas last_name: Lundholm - first_name: Phan full_name: Nam, Phan id: 404092F4-F248-11E8-B48F-1D18A9856A87 last_name: Nam - first_name: Fabian full_name: Portmann, Fabian last_name: Portmann citation: ama: Lundholm D, Nam P, Portmann F. Fractional Hardy–Lieb–Thirring and related Inequalities for interacting systems. Archive for Rational Mechanics and Analysis. 2016;219(3):1343-1382. doi:10.1007/s00205-015-0923-5 apa: Lundholm, D., Nam, P., & Portmann, F. (2016). Fractional Hardy–Lieb–Thirring and related Inequalities for interacting systems. Archive for Rational Mechanics and Analysis. Springer. https://doi.org/10.1007/s00205-015-0923-5 chicago: Lundholm, Douglas, Phan Nam, and Fabian Portmann. “Fractional Hardy–Lieb–Thirring and Related Inequalities for Interacting Systems.” Archive for Rational Mechanics and Analysis. Springer, 2016. https://doi.org/10.1007/s00205-015-0923-5. ieee: D. Lundholm, P. Nam, and F. Portmann, “Fractional Hardy–Lieb–Thirring and related Inequalities for interacting systems,” Archive for Rational Mechanics and Analysis, vol. 219, no. 3. Springer, pp. 1343–1382, 2016. ista: Lundholm D, Nam P, Portmann F. 2016. Fractional Hardy–Lieb–Thirring and related Inequalities for interacting systems. Archive for Rational Mechanics and Analysis. 219(3), 1343–1382. mla: Lundholm, Douglas, et al. “Fractional Hardy–Lieb–Thirring and Related Inequalities for Interacting Systems.” Archive for Rational Mechanics and Analysis, vol. 219, no. 3, Springer, 2016, pp. 1343–82, doi:10.1007/s00205-015-0923-5. short: D. Lundholm, P. Nam, F. Portmann, Archive for Rational Mechanics and Analysis 219 (2016) 1343–1382. corr_author: '1' date_created: 2018-12-11T11:53:05Z date_published: 2016-03-01T00:00:00Z date_updated: 2025-09-18T10:52:35Z day: '01' department: - _id: RoSe doi: 10.1007/s00205-015-0923-5 ec_funded: 1 external_id: arxiv: - '1501.04570' isi: - '000368535400010' intvolume: ' 219' isi: 1 issue: '3' language: - iso: eng main_file_link: - open_access: '1' url: http://arxiv.org/abs/1501.04570 month: '03' oa: 1 oa_version: Submitted Version page: 1343 - 1382 project: - _id: 25681D80-B435-11E9-9278-68D0E5697425 call_identifier: FP7 grant_number: '291734' name: International IST Postdoc Fellowship Programme publication: Archive for Rational Mechanics and Analysis publication_status: published publisher: Springer publist_id: '5542' quality_controlled: '1' scopus_import: '1' status: public title: Fractional Hardy–Lieb–Thirring and related Inequalities for interacting systems type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 219 year: '2016' ... --- _id: '1631' abstract: - lang: eng text: 'Ancestral processes are fundamental to modern population genetics and spatial structure has been the subject of intense interest for many years. Despite this interest, almost nothing is known about the distribution of the locations of pedigree or genetic ancestors. Using both spatially continuous and stepping-stone models, we show that the distribution of pedigree ancestors approaches a travelling wave, for which we develop two alternative approximations. The speed and width of the wave are sensitive to the local details of the model. After a short time, genetic ancestors spread far more slowly than pedigree ancestors, ultimately diffusing out with radius ## rather than spreading at constant speed. In contrast to the wave of pedigree ancestors, the spread of genetic ancestry is insensitive to the local details of the models.' article_processing_charge: No author: - first_name: Jerome full_name: Kelleher, Jerome last_name: Kelleher - first_name: Alison full_name: Etheridge, Alison last_name: Etheridge - first_name: Amandine full_name: Véber, Amandine last_name: Véber - first_name: Nicholas H full_name: Barton, Nicholas H id: 4880FE40-F248-11E8-B48F-1D18A9856A87 last_name: Barton orcid: 0000-0002-8548-5240 citation: ama: Kelleher J, Etheridge A, Véber A, Barton NH. Spread of pedigree versus genetic ancestry in spatially distributed populations. Theoretical Population Biology. 2016;108:1-12. doi:10.1016/j.tpb.2015.10.008 apa: Kelleher, J., Etheridge, A., Véber, A., & Barton, N. H. (2016). Spread of pedigree versus genetic ancestry in spatially distributed populations. Theoretical Population Biology. Academic Press. https://doi.org/10.1016/j.tpb.2015.10.008 chicago: Kelleher, Jerome, Alison Etheridge, Amandine Véber, and Nicholas H Barton. “Spread of Pedigree versus Genetic Ancestry in Spatially Distributed Populations.” Theoretical Population Biology. Academic Press, 2016. https://doi.org/10.1016/j.tpb.2015.10.008. ieee: J. Kelleher, A. Etheridge, A. Véber, and N. H. Barton, “Spread of pedigree versus genetic ancestry in spatially distributed populations,” Theoretical Population Biology, vol. 108. Academic Press, pp. 1–12, 2016. ista: Kelleher J, Etheridge A, Véber A, Barton NH. 2016. Spread of pedigree versus genetic ancestry in spatially distributed populations. Theoretical Population Biology. 108, 1–12. mla: Kelleher, Jerome, et al. “Spread of Pedigree versus Genetic Ancestry in Spatially Distributed Populations.” Theoretical Population Biology, vol. 108, Academic Press, 2016, pp. 1–12, doi:10.1016/j.tpb.2015.10.008. short: J. Kelleher, A. Etheridge, A. Véber, N.H. Barton, Theoretical Population Biology 108 (2016) 1–12. corr_author: '1' date_created: 2018-12-11T11:53:08Z date_published: 2016-04-01T00:00:00Z date_updated: 2025-09-18T10:51:58Z day: '01' ddc: - '576' department: - _id: NiBa doi: 10.1016/j.tpb.2015.10.008 ec_funded: 1 external_id: isi: - '000372560000001' file: - access_level: open_access checksum: 6a65ba187994d4ad86c1c509e0ff482a content_type: application/pdf creator: system date_created: 2018-12-12T10:11:12Z date_updated: 2020-07-14T12:45:07Z file_id: '4865' file_name: IST-2016-465-v1+1_1-s2.0-S0040580915001094-main.pdf file_size: 1684043 relation: main_file file_date_updated: 2020-07-14T12:45:07Z has_accepted_license: '1' intvolume: ' 108' isi: 1 language: - iso: eng month: '04' oa: 1 oa_version: Published Version page: 1 - 12 project: - _id: 25B07788-B435-11E9-9278-68D0E5697425 call_identifier: FP7 grant_number: '250152' name: Limits to selection in biology and in evolutionary computation publication: Theoretical Population Biology publication_status: published publisher: Academic Press publist_id: '5524' pubrep_id: '465' quality_controlled: '1' scopus_import: '1' status: public title: Spread of pedigree versus genetic ancestry in spatially distributed populations tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 108 year: '2016' ... --- _id: '1641' abstract: - lang: eng text: The plant hormone auxin (indole-3-acetic acid) is a major regulator of plant growth and development including embryo and root patterning, lateral organ formation and growth responses to environmental stimuli. Auxin is directionally transported from cell to cell by the action of specific auxin influx [AUXIN-RESISTANT1 (AUX1)] and efflux [PIN-FORMED (PIN)] transport regulators, whose polar, subcellular localizations are aligned with the direction of the auxin flow. Auxin itself regulates its own transport by modulation of the expression and subcellular localization of the auxin transporters. Increased auxin levels promote the transcription of PIN2 and AUX1 genes as well as stabilize PIN proteins at the plasma membrane, whereas prolonged auxin exposure increases the turnover of PIN proteins and their degradation in the vacuole. In this study, we applied a forward genetic approach, to identify molecular components playing a role in the auxin-mediated degradation. We generated EMS-mutagenized Arabidopsis PIN2::PIN2:GFP, AUX1::AUX1:YFP eir1aux1 populations and designed a screen for mutants with persistently strong fluorescent signals of the tagged PIN2 and AUX1 after prolonged treatment with the synthetic auxin 2,4-dichlorophenoxyacetic acid (2,4-D). This approach yielded novel auxin degradation mutants defective in trafficking and degradation of PIN2 and AUX1 proteins and established a role for auxin-mediated degradation in plant development. acknowledgement: 'European Social Fund (CZ.1.07/2.3.00/20.0043) and the Czech Science Foundation GAČR (GA13-40637S) to JF. ' article_processing_charge: No author: - first_name: Radka full_name: Zemová, Radka last_name: Zemová - first_name: Marta full_name: Zwiewka, Marta last_name: Zwiewka - first_name: Agnieszka full_name: Bielach, Agnieszka last_name: Bielach - first_name: Hélène full_name: Robert, Hélène last_name: Robert - first_name: Jirí full_name: Friml, Jirí id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 citation: ama: Zemová R, Zwiewka M, Bielach A, Robert H, Friml J. A forward genetic screen for new regulators of auxin mediated degradation of auxin transport proteins in Arabidopsis thaliana. Journal of Plant Growth Regulation. 2016;35(2):465-476. doi:10.1007/s00344-015-9553-2 apa: Zemová, R., Zwiewka, M., Bielach, A., Robert, H., & Friml, J. (2016). A forward genetic screen for new regulators of auxin mediated degradation of auxin transport proteins in Arabidopsis thaliana. Journal of Plant Growth Regulation. Springer. https://doi.org/10.1007/s00344-015-9553-2 chicago: Zemová, Radka, Marta Zwiewka, Agnieszka Bielach, Hélène Robert, and Jiří Friml. “A Forward Genetic Screen for New Regulators of Auxin Mediated Degradation of Auxin Transport Proteins in Arabidopsis Thaliana.” Journal of Plant Growth Regulation. Springer, 2016. https://doi.org/10.1007/s00344-015-9553-2. ieee: R. Zemová, M. Zwiewka, A. Bielach, H. Robert, and J. Friml, “A forward genetic screen for new regulators of auxin mediated degradation of auxin transport proteins in Arabidopsis thaliana,” Journal of Plant Growth Regulation, vol. 35, no. 2. Springer, pp. 465–476, 2016. ista: Zemová R, Zwiewka M, Bielach A, Robert H, Friml J. 2016. A forward genetic screen for new regulators of auxin mediated degradation of auxin transport proteins in Arabidopsis thaliana. Journal of Plant Growth Regulation. 35(2), 465–476. mla: Zemová, Radka, et al. “A Forward Genetic Screen for New Regulators of Auxin Mediated Degradation of Auxin Transport Proteins in Arabidopsis Thaliana.” Journal of Plant Growth Regulation, vol. 35, no. 2, Springer, 2016, pp. 465–76, doi:10.1007/s00344-015-9553-2. short: R. Zemová, M. Zwiewka, A. Bielach, H. Robert, J. Friml, Journal of Plant Growth Regulation 35 (2016) 465–476. corr_author: '1' date_created: 2018-12-11T11:53:12Z date_published: 2016-06-01T00:00:00Z date_updated: 2025-09-18T10:51:26Z day: '01' ddc: - '581' department: - _id: JiFr doi: 10.1007/s00344-015-9553-2 external_id: isi: - '000376482300015' file: - access_level: open_access checksum: 0dc6a300cde6536ceedd2bcdd2060efb content_type: application/pdf creator: system date_created: 2018-12-12T10:08:34Z date_updated: 2020-07-14T12:45:08Z file_id: '4695' file_name: IST-2018-1001-v1+1_Zemova_JPlantGrowthRegul_2016_proofs.pdf file_size: 5637591 relation: main_file file_date_updated: 2020-07-14T12:45:08Z has_accepted_license: '1' intvolume: ' 35' isi: 1 issue: '2' language: - iso: eng month: '06' oa: 1 oa_version: Preprint page: 465 - 476 publication: Journal of Plant Growth Regulation publication_status: published publisher: Springer publist_id: '5512' pubrep_id: '1001' quality_controlled: '1' scopus_import: '1' status: public title: A forward genetic screen for new regulators of auxin mediated degradation of auxin transport proteins in Arabidopsis thaliana type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 35 year: '2016' ... --- _id: '1653' abstract: - lang: eng text: "A somewhere statistically binding (SSB) hash, introduced by Hubáček and Wichs (ITCS ’15), can be used to hash a long string x to a short digest y = H hk (x) using a public hashing-key hk. Furthermore, there is a way to set up the hash key hk to make it statistically binding on some arbitrary hidden position i, meaning that: (1) the digest y completely determines the i’th bit (or symbol) of x so that all pre-images of y have the same value in the i’th position, (2) it is computationally infeasible to distinguish the position i on which hk is statistically binding from any other position i’. Lastly, the hash should have a local opening property analogous to Merkle-Tree hashing, meaning that given x and y = H hk (x) it should be possible to create a short proof π that certifies the value of the i’th bit (or symbol) of x without having to provide the entire input x. A similar primitive called a positional accumulator, introduced by Koppula, Lewko and Waters (STOC ’15) further supports dynamic updates of the hashed value. These tools, which are interesting in their own right, also serve as one of the main technical components in several recent works building advanced applications from indistinguishability obfuscation (iO).\r\n\r\nThe prior constructions of SSB hashing and positional accumulators required fully homomorphic encryption (FHE) and iO respectively. In this work, we give new constructions of these tools based on well studied number-theoretic assumptions such as DDH, Phi-Hiding and DCR, as well as a general construction from lossy/injective functions." alternative_title: - LNCS article_processing_charge: No author: - first_name: Tatsuaki full_name: Okamoto, Tatsuaki last_name: Okamoto - first_name: Krzysztof Z full_name: Pietrzak, Krzysztof Z id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87 last_name: Pietrzak orcid: 0000-0002-9139-1654 - first_name: Brent full_name: Waters, Brent last_name: Waters - first_name: Daniel full_name: Wichs, Daniel last_name: Wichs citation: ama: 'Okamoto T, Pietrzak KZ, Waters B, Wichs D. New realizations of somewhere statistically binding hashing and positional accumulators. In: Vol 9452. Springer; 2016:121-145. doi:10.1007/978-3-662-48797-6_6' apa: 'Okamoto, T., Pietrzak, K. Z., Waters, B., & Wichs, D. (2016). New realizations of somewhere statistically binding hashing and positional accumulators (Vol. 9452, pp. 121–145). Presented at the ASIACRYPT: Theory and Application of Cryptology and Information Security, Auckland, New Zealand: Springer. https://doi.org/10.1007/978-3-662-48797-6_6' chicago: Okamoto, Tatsuaki, Krzysztof Z Pietrzak, Brent Waters, and Daniel Wichs. “New Realizations of Somewhere Statistically Binding Hashing and Positional Accumulators,” 9452:121–45. Springer, 2016. https://doi.org/10.1007/978-3-662-48797-6_6. ieee: 'T. Okamoto, K. Z. Pietrzak, B. Waters, and D. Wichs, “New realizations of somewhere statistically binding hashing and positional accumulators,” presented at the ASIACRYPT: Theory and Application of Cryptology and Information Security, Auckland, New Zealand, 2016, vol. 9452, pp. 121–145.' ista: 'Okamoto T, Pietrzak KZ, Waters B, Wichs D. 2016. New realizations of somewhere statistically binding hashing and positional accumulators. ASIACRYPT: Theory and Application of Cryptology and Information Security, LNCS, vol. 9452, 121–145.' mla: Okamoto, Tatsuaki, et al. New Realizations of Somewhere Statistically Binding Hashing and Positional Accumulators. Vol. 9452, Springer, 2016, pp. 121–45, doi:10.1007/978-3-662-48797-6_6. short: T. Okamoto, K.Z. Pietrzak, B. Waters, D. Wichs, in:, Springer, 2016, pp. 121–145. conference: end_date: 2015-12-03 location: Auckland, New Zealand name: 'ASIACRYPT: Theory and Application of Cryptology and Information Security' start_date: 2015-11-29 date_created: 2018-12-11T11:53:16Z date_published: 2016-01-08T00:00:00Z date_updated: 2025-09-23T09:40:30Z day: '08' ddc: - '000' department: - _id: KrPi doi: 10.1007/978-3-662-48797-6_6 ec_funded: 1 external_id: isi: - '000375148100006' file: - access_level: open_access checksum: a57711cb660c5b17b42bb47275a00180 content_type: application/pdf creator: system date_created: 2018-12-12T10:12:05Z date_updated: 2020-07-14T12:45:08Z file_id: '4923' file_name: IST-2016-677-v1+1_869.pdf file_size: 580088 relation: main_file file_date_updated: 2020-07-14T12:45:08Z has_accepted_license: '1' intvolume: ' 9452' isi: 1 language: - iso: eng month: '01' oa: 1 oa_version: Submitted Version page: 121 - 145 project: - _id: 258C570E-B435-11E9-9278-68D0E5697425 call_identifier: FP7 grant_number: '259668' name: Provable Security for Physical Cryptography publication_status: published publisher: Springer publist_id: '5497' pubrep_id: '677' quality_controlled: '1' scopus_import: '1' status: public title: New realizations of somewhere statistically binding hashing and positional accumulators type: conference user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 9452 year: '2016' ... --- _id: '1705' abstract: - lang: eng text: Hybrid systems represent an important and powerful formalism for modeling real-world applications such as embedded systems. A verification tool like SpaceEx is based on the exploration of a symbolic search space (the region space). As a verification tool, it is typically optimized towards proving the absence of errors. In some settings, e.g., when the verification tool is employed in a feedback-directed design cycle, one would like to have the option to call a version that is optimized towards finding an error trajectory in the region space. A recent approach in this direction is based on guided search. Guided search relies on a cost function that indicates which states are promising to be explored, and preferably explores more promising states first. In this paper, we propose an abstraction-based cost function based on coarse-grained space abstractions for guiding the reachability analysis. For this purpose, a suitable abstraction technique that exploits the flexible granularity of modern reachability analysis algorithms is introduced. The new cost function is an effective extension of pattern database approaches that have been successfully applied in other areas. The approach has been implemented in the SpaceEx model checker. The evaluation shows its practical potential. article_processing_charge: Yes (via OA deal) author: - first_name: Sergiy full_name: Bogomolov, Sergiy id: 369D9A44-F248-11E8-B48F-1D18A9856A87 last_name: Bogomolov orcid: 0000-0002-0686-0365 - first_name: Alexandre full_name: Donzé, Alexandre last_name: Donzé - first_name: Goran full_name: Frehse, Goran last_name: Frehse - first_name: Radu full_name: Grosu, Radu last_name: Grosu - first_name: Taylor full_name: Johnson, Taylor last_name: Johnson - first_name: Hamed full_name: Ladan, Hamed last_name: Ladan - first_name: Andreas full_name: Podelski, Andreas last_name: Podelski - first_name: Martin full_name: Wehrle, Martin last_name: Wehrle citation: ama: Bogomolov S, Donzé A, Frehse G, et al. Guided search for hybrid systems based on coarse-grained space abstractions. International Journal on Software Tools for Technology Transfer. 2016;18(4):449-467. doi:10.1007/s10009-015-0393-y apa: Bogomolov, S., Donzé, A., Frehse, G., Grosu, R., Johnson, T., Ladan, H., … Wehrle, M. (2016). Guided search for hybrid systems based on coarse-grained space abstractions. International Journal on Software Tools for Technology Transfer. Springer. https://doi.org/10.1007/s10009-015-0393-y chicago: Bogomolov, Sergiy, Alexandre Donzé, Goran Frehse, Radu Grosu, Taylor Johnson, Hamed Ladan, Andreas Podelski, and Martin Wehrle. “Guided Search for Hybrid Systems Based on Coarse-Grained Space Abstractions.” International Journal on Software Tools for Technology Transfer. Springer, 2016. https://doi.org/10.1007/s10009-015-0393-y. ieee: S. Bogomolov et al., “Guided search for hybrid systems based on coarse-grained space abstractions,” International Journal on Software Tools for Technology Transfer, vol. 18, no. 4. Springer, pp. 449–467, 2016. ista: Bogomolov S, Donzé A, Frehse G, Grosu R, Johnson T, Ladan H, Podelski A, Wehrle M. 2016. Guided search for hybrid systems based on coarse-grained space abstractions. International Journal on Software Tools for Technology Transfer. 18(4), 449–467. mla: Bogomolov, Sergiy, et al. “Guided Search for Hybrid Systems Based on Coarse-Grained Space Abstractions.” International Journal on Software Tools for Technology Transfer, vol. 18, no. 4, Springer, 2016, pp. 449–67, doi:10.1007/s10009-015-0393-y. short: S. Bogomolov, A. Donzé, G. Frehse, R. Grosu, T. Johnson, H. Ladan, A. Podelski, M. Wehrle, International Journal on Software Tools for Technology Transfer 18 (2016) 449–467. corr_author: '1' date_created: 2018-12-11T11:53:34Z date_published: 2016-08-01T00:00:00Z date_updated: 2025-09-18T10:50:19Z day: '01' ddc: - '000' department: - _id: ToHe doi: 10.1007/s10009-015-0393-y ec_funded: 1 external_id: isi: - '000379708300007' file: - access_level: open_access checksum: 31561d7705599a9bd4ea816accc0752e content_type: application/pdf creator: system date_created: 2018-12-12T10:15:26Z date_updated: 2020-07-14T12:45:13Z file_id: '5146' file_name: IST-2016-457-v1+1_s10009-015-0393-y.pdf file_size: 2296522 relation: main_file file_date_updated: 2020-07-14T12:45:13Z has_accepted_license: '1' intvolume: ' 18' isi: 1 issue: '4' language: - iso: eng month: '08' oa: 1 oa_version: Published Version page: 449 - 467 project: - _id: 25EE3708-B435-11E9-9278-68D0E5697425 call_identifier: FP7 grant_number: '267989' name: Quantitative Reactive Modeling - _id: 25F42A32-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: Z211 name: Formal methods for the design and analysis of complex systems - _id: 25832EC2-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: S 11407_N23 name: Rigorous Systems Engineering publication: International Journal on Software Tools for Technology Transfer publication_status: published publisher: Springer publist_id: '5431' pubrep_id: '457' quality_controlled: '1' scopus_import: '1' status: public title: Guided search for hybrid systems based on coarse-grained space abstractions tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 18 year: '2016' ... --- _id: '1707' abstract: - lang: eng text: "Volunteer supporters play an important role in modern crisis and disaster management. In the times of mobile Internet devices, help from thousands of volunteers can be requested within a short time span, thus relieving professional helpers from minor chores or geographically spread-out tasks. However, the simultaneous availability of many volunteers also poses new problems. In particular, the volunteer efforts must be well coordinated, or otherwise situations might emerge in which too many idle volunteers at one location become more of a burden than a relief to the professionals.\r\nIn this work, we study the task of optimally assigning volunteers to selected locations, e.g. in order to perform regular measurements, to report on damage, or to distribute information or resources to the population in a crisis situation. We formulate the assignment tasks as an optimization problem and propose an effective and efficient solution procedure. Experiments on real data of the Team Österreich, consisting of over 36,000 Austrian volunteers, show the effectiveness and efficiency of our approach." acknowledgement: The DRIVER FP7 project has received funding from the European Unions Seventh Framework Programme for research, technological development and demonstration under grant agreement no 607798. RE-ACTA was funded within the framework of the Austrian Security Research Programme KIRAS by the Federal Ministry for Transport, Innovation and Technology. article_number: '7402041' author: - first_name: Jasmin full_name: Pielorz, Jasmin id: 49BC895A-F248-11E8-B48F-1D18A9856A87 last_name: Pielorz - first_name: Christoph full_name: Lampert, Christoph id: 40C20FD2-F248-11E8-B48F-1D18A9856A87 last_name: Lampert orcid: 0000-0001-8622-7887 citation: ama: 'Pielorz J, Lampert C. Optimal geospatial allocation of volunteers for crisis management. In: IEEE; 2016. doi:10.1109/ICT-DM.2015.7402041' apa: 'Pielorz, J., & Lampert, C. (2016). Optimal geospatial allocation of volunteers for crisis management. Presented at the ICT-DM: Information and Communication Technologies for Disaster Management, Rennes, France: IEEE. https://doi.org/10.1109/ICT-DM.2015.7402041' chicago: Pielorz, Jasmin, and Christoph Lampert. “Optimal Geospatial Allocation of Volunteers for Crisis Management.” IEEE, 2016. https://doi.org/10.1109/ICT-DM.2015.7402041. ieee: 'J. Pielorz and C. Lampert, “Optimal geospatial allocation of volunteers for crisis management,” presented at the ICT-DM: Information and Communication Technologies for Disaster Management, Rennes, France, 2016.' ista: 'Pielorz J, Lampert C. 2016. Optimal geospatial allocation of volunteers for crisis management. ICT-DM: Information and Communication Technologies for Disaster Management, 7402041.' mla: Pielorz, Jasmin, and Christoph Lampert. Optimal Geospatial Allocation of Volunteers for Crisis Management. 7402041, IEEE, 2016, doi:10.1109/ICT-DM.2015.7402041. short: J. Pielorz, C. Lampert, in:, IEEE, 2016. conference: end_date: 2015-12-02 location: Rennes, France name: 'ICT-DM: Information and Communication Technologies for Disaster Management' start_date: 2015-11-30 date_created: 2018-12-11T11:53:35Z date_published: 2016-02-11T00:00:00Z date_updated: 2021-01-12T06:52:39Z day: '11' department: - _id: ChLa doi: 10.1109/ICT-DM.2015.7402041 language: - iso: eng month: '02' oa_version: None publication_status: published publisher: IEEE publist_id: '5429' quality_controlled: '1' scopus_import: 1 status: public title: Optimal geospatial allocation of volunteers for crisis management type: conference user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87 year: '2016' ... --- _id: '173' abstract: - lang: eng text: We calculate admissible values of r such that a square-free polynomial with integer coefficients, no fixed prime divisor and irreducible factors of degree at most 3 takes infinitely many values that are a product of at most r distinct primes. article_processing_charge: No article_type: original arxiv: 1 author: - first_name: Timothy D full_name: Browning, Timothy D id: 35827D50-F248-11E8-B48F-1D18A9856A87 last_name: Browning orcid: 0000-0002-8314-0177 - first_name: Andrew full_name: Booker, Andrew last_name: Booker citation: ama: Browning TD, Booker A. Square-free values of reducible polynomials. Discrete Analysis. 2016;8:1-18. doi:10.19086/da.732 apa: Browning, T. D., & Booker, A. (2016). Square-free values of reducible polynomials. Discrete Analysis. https://doi.org/10.19086/da.732 chicago: Browning, Timothy D, and Andrew Booker. “Square-Free Values of Reducible Polynomials.” Discrete Analysis, 2016. https://doi.org/10.19086/da.732. ieee: T. D. Browning and A. Booker, “Square-free values of reducible polynomials,” Discrete Analysis, vol. 8. pp. 1–18, 2016. ista: Browning TD, Booker A. 2016. Square-free values of reducible polynomials. Discrete Analysis. 8, 1–18. mla: Browning, Timothy D., and Andrew Booker. “Square-Free Values of Reducible Polynomials.” Discrete Analysis, vol. 8, 2016, pp. 1–18, doi:10.19086/da.732. short: T.D. Browning, A. Booker, Discrete Analysis 8 (2016) 1–18. date_created: 2018-12-11T11:45:00Z date_published: 2016-06-01T00:00:00Z date_updated: 2021-01-12T06:52:49Z day: '01' doi: 10.19086/da.732 extern: '1' external_id: arxiv: - '1511.00601' intvolume: ' 8' language: - iso: eng main_file_link: - open_access: '1' url: https://arxiv.org/abs/1511.00601 month: '06' oa: 1 oa_version: Preprint page: 1 - 18 publication: Discrete Analysis publication_status: published publist_id: '7748' quality_controlled: '1' status: public title: Square-free values of reducible polynomials type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 8 year: '2016' ... --- _id: '17618' abstract: - lang: eng text: The largest observed supermassive black holes (SMBHs) have a mass of M_BH ~ 10^{10} M_sun, nearly independent of redshift, from the local (z~0) to the early (z>6) Universe. We suggest that the growth of SMBHs above a few 10^{10} M_sun is prevented by small-scale accretion physics, independent of the properties of their host galaxies or of cosmology. Growing more massive BHs requires a gas supply rate from galactic scales onto a nuclear region as high as >10^3 M_sun/yr. At such a high accretion rate, most of the gas converts to stars at large radii (~10-100 pc), well before reaching the BH. We adopt a simple model (Thompson et al. 2005) for a star-forming accretion disk, and find that the accretion rate in the sub-pc nuclear region is reduced to the smaller value of at most a few M_sun/yr. This prevents SMBHs from growing above ~10^{11} M_sun in the age of the Universe. Furthermore, once a SMBH reaches a sufficiently high mass, this rate falls below the critical value at which the accretion flow becomes advection dominated. Once this transition occurs, BH feeding can be suppressed by strong outflows and jets from hot gas near the BH. We find that the maximum SMBH mass, given by this transition, is between M_{BH,max} ~ (1-6) * 10^{10} M_sun, depending primarily on the efficiency of angular momentum transfer inside the galactic disk, and not on other properties of the host galaxy. article_number: '110' article_processing_charge: No article_type: original arxiv: 1 author: - first_name: Kohei full_name: Inayoshi, Kohei last_name: Inayoshi - first_name: Zoltán full_name: Haiman, Zoltán id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36 last_name: Haiman citation: ama: Inayoshi K, Haiman Z. Is there a maximum mass for black holes in galactic nuclei? The Astrophysical Journal. 2016;828(2). doi:10.3847/0004-637x/828/2/110 apa: Inayoshi, K., & Haiman, Z. (2016). Is there a maximum mass for black holes in galactic nuclei? The Astrophysical Journal. American Astronomical Society. https://doi.org/10.3847/0004-637x/828/2/110 chicago: Inayoshi, Kohei, and Zoltán Haiman. “Is There a Maximum Mass for Black Holes in Galactic Nuclei?” The Astrophysical Journal. American Astronomical Society, 2016. https://doi.org/10.3847/0004-637x/828/2/110. ieee: K. Inayoshi and Z. Haiman, “Is there a maximum mass for black holes in galactic nuclei?,” The Astrophysical Journal, vol. 828, no. 2. American Astronomical Society, 2016. ista: Inayoshi K, Haiman Z. 2016. Is there a maximum mass for black holes in galactic nuclei? The Astrophysical Journal. 828(2), 110. mla: Inayoshi, Kohei, and Zoltán Haiman. “Is There a Maximum Mass for Black Holes in Galactic Nuclei?” The Astrophysical Journal, vol. 828, no. 2, 110, American Astronomical Society, 2016, doi:10.3847/0004-637x/828/2/110. short: K. Inayoshi, Z. Haiman, The Astrophysical Journal 828 (2016). date_created: 2024-09-05T13:44:44Z date_published: 2016-09-12T00:00:00Z date_updated: 2024-09-24T08:11:51Z day: '12' doi: 10.3847/0004-637x/828/2/110 extern: '1' external_id: arxiv: - '1601.02611' intvolume: ' 828' issue: '2' language: - iso: eng main_file_link: - open_access: '1' url: ' https://doi.org/10.48550/arXiv.1601.02611' month: '09' oa: 1 oa_version: Preprint publication: The Astrophysical Journal publication_identifier: issn: - 0004-637X - 1538-4357 publication_status: published publisher: American Astronomical Society quality_controlled: '1' scopus_import: '1' status: public title: Is there a maximum mass for black holes in galactic nuclei? type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 828 year: '2016' ... --- _id: '17621' abstract: - lang: eng text: We introduce an intrinsic Lyα emission-line profile reconstruction method for high-z quasars (QSOs). This approach utilises a covariance matrix of emission-line properties obtained from a large, moderate-z (2 ≤ z ≤ 2.5), high signal to noise (S/N > 15) sample of BOSS QSOs. For each QSO, we complete a Monte Carlo Markov Chain fitting of the continuum and emission-line properties and perform a visual quality assessment to construct a large data base of robustly fit spectra. With this data set, we construct a covariance matrix to describe the correlations between the high-ionization emission lines Lyα, C iv, Si iv +O iv] and C iii], and find it to be well approximated by an N-dimensional Gaussian distribution. This covariance matrix characterizes the correlations between the linewidth, peak height and velocity offset from systemic while also allowing for the existence of broad- and narrow-line components for Lyα and C iv. We illustrate how this covariance matrix allows us to statistically characterize the intrinsic Lyα line solely from the observed spectrum redward of 1275 Å. This procedure can be used to reconstruct the intrinsic Lyα line emission profile in cases where Lyα may otherwise be obscured. Applying this reconstruction method to our sample of QSOs, we recovered the Lyα line flux to within 15 per cent of the measured flux at 1205 Å (1220 Å) ∼85 (90) per cent of the time. article_processing_charge: No article_type: original author: - first_name: Bradley full_name: Greig, Bradley last_name: Greig - first_name: Andrei full_name: Mesinger, Andrei last_name: Mesinger - first_name: Ian D. full_name: McGreer, Ian D. last_name: McGreer - first_name: Simona full_name: Gallerani, Simona last_name: Gallerani - first_name: Zoltán full_name: Haiman, Zoltán id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36 last_name: Haiman citation: ama: Greig B, Mesinger A, McGreer ID, Gallerani S, Haiman Z. Lyα emission-line reconstruction for high-z QSOs. Monthly Notices of the Royal Astronomical Society. 2016;466(2):1814-1838. doi:10.1093/mnras/stw3210 apa: Greig, B., Mesinger, A., McGreer, I. D., Gallerani, S., & Haiman, Z. (2016). Lyα emission-line reconstruction for high-z QSOs. Monthly Notices of the Royal Astronomical Society. Oxford University Press. https://doi.org/10.1093/mnras/stw3210 chicago: Greig, Bradley, Andrei Mesinger, Ian D. McGreer, Simona Gallerani, and Zoltán Haiman. “Lyα Emission-Line Reconstruction for High-z QSOs.” Monthly Notices of the Royal Astronomical Society. Oxford University Press, 2016. https://doi.org/10.1093/mnras/stw3210. ieee: B. Greig, A. Mesinger, I. D. McGreer, S. Gallerani, and Z. Haiman, “Lyα emission-line reconstruction for high-z QSOs,” Monthly Notices of the Royal Astronomical Society, vol. 466, no. 2. Oxford University Press, pp. 1814–1838, 2016. ista: Greig B, Mesinger A, McGreer ID, Gallerani S, Haiman Z. 2016. Lyα emission-line reconstruction for high-z QSOs. Monthly Notices of the Royal Astronomical Society. 466(2), 1814–1838. mla: Greig, Bradley, et al. “Lyα Emission-Line Reconstruction for High-z QSOs.” Monthly Notices of the Royal Astronomical Society, vol. 466, no. 2, Oxford University Press, 2016, pp. 1814–38, doi:10.1093/mnras/stw3210. short: B. Greig, A. Mesinger, I.D. McGreer, S. Gallerani, Z. Haiman, Monthly Notices of the Royal Astronomical Society 466 (2016) 1814–1838. date_created: 2024-09-05T13:49:52Z date_published: 2016-12-10T00:00:00Z date_updated: 2024-09-24T08:31:25Z day: '10' doi: 10.1093/mnras/stw3210 extern: '1' intvolume: ' 466' issue: '2' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1093/mnras/stw3210 month: '12' oa: 1 oa_version: Published Version page: 1814-1838 publication: Monthly Notices of the Royal Astronomical Society publication_identifier: issn: - 0035-8711 - 1365-2966 publication_status: published publisher: Oxford University Press quality_controlled: '1' scopus_import: '1' status: public title: Lyα emission-line reconstruction for high-z QSOs type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 466 year: '2016' ...