---
_id: '1944'
acknowledgement: This work was supported by the European Research Council (project
  ERC-2011-StG-20101109-PSDP); the Agency for Innovation by Science and Technology
  (IWT) (predoctoral fellowship to H.R.); and the People Programme (Marie Curie Actions)
  of the European Union
article_processing_charge: No
author:
- first_name: Hana
  full_name: Rakusová, Hana
  last_name: Rakusová
- first_name: Matyas
  full_name: Fendrych, Matyas
  id: 43905548-F248-11E8-B48F-1D18A9856A87
  last_name: Fendrych
  orcid: 0000-0002-9767-8699
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Rakusová H, Fendrych M, Friml J. Intracellular trafficking and PIN-mediated
    cell polarity during tropic responses in plants. <i>Current Opinion in Plant Biology</i>.
    2015;23(2):116-123. doi:<a href="https://doi.org/10.1016/j.pbi.2014.12.002">10.1016/j.pbi.2014.12.002</a>
  apa: Rakusová, H., Fendrych, M., &#38; Friml, J. (2015). Intracellular trafficking
    and PIN-mediated cell polarity during tropic responses in plants. <i>Current Opinion
    in Plant Biology</i>. Elsevier. <a href="https://doi.org/10.1016/j.pbi.2014.12.002">https://doi.org/10.1016/j.pbi.2014.12.002</a>
  chicago: Rakusová, Hana, Matyas Fendrych, and Jiří Friml. “Intracellular Trafficking
    and PIN-Mediated Cell Polarity during Tropic Responses in Plants.” <i>Current
    Opinion in Plant Biology</i>. Elsevier, 2015. <a href="https://doi.org/10.1016/j.pbi.2014.12.002">https://doi.org/10.1016/j.pbi.2014.12.002</a>.
  ieee: H. Rakusová, M. Fendrych, and J. Friml, “Intracellular trafficking and PIN-mediated
    cell polarity during tropic responses in plants,” <i>Current Opinion in Plant
    Biology</i>, vol. 23, no. 2. Elsevier, pp. 116–123, 2015.
  ista: Rakusová H, Fendrych M, Friml J. 2015. Intracellular trafficking and PIN-mediated
    cell polarity during tropic responses in plants. Current Opinion in Plant Biology.
    23(2), 116–123.
  mla: Rakusová, Hana, et al. “Intracellular Trafficking and PIN-Mediated Cell Polarity
    during Tropic Responses in Plants.” <i>Current Opinion in Plant Biology</i>, vol.
    23, no. 2, Elsevier, 2015, pp. 116–23, doi:<a href="https://doi.org/10.1016/j.pbi.2014.12.002">10.1016/j.pbi.2014.12.002</a>.
  short: H. Rakusová, M. Fendrych, J. Friml, Current Opinion in Plant Biology 23 (2015)
    116–123.
corr_author: '1'
date_created: 2018-12-11T11:54:51Z
date_published: 2015-02-01T00:00:00Z
date_updated: 2025-09-23T09:23:09Z
day: '01'
department:
- _id: JiFr
doi: 10.1016/j.pbi.2014.12.002
ec_funded: 1
external_id:
  isi:
  - '000349880900017'
intvolume: '        23'
isi: 1
issue: '2'
language:
- iso: eng
month: '02'
oa_version: None
page: 116 - 123
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '282300'
  name: Polarity and subcellular dynamics in plants
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication: Current Opinion in Plant Biology
publication_status: published
publisher: Elsevier
publist_id: '5140'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Intracellular trafficking and PIN-mediated cell polarity during tropic responses
  in plants
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 23
year: '2015'
...
---
_id: '1481'
abstract:
- lang: eng
  text: 'Simple board games, like Tic-Tac-Toe and CONNECT-4, play an important role
    not only in the development of mathematical and logical skills, but also in the
    emotional and social development. In this paper, we address the problem of generating
    targeted starting positions for such games. This can facilitate new approaches
    for bringing novice players to mastery, and also leads to discovery of interesting
    game variants. We present an approach that generates starting states of varying
    hardness levels for player 1 in a two-player board game, given rules of the board
    game, the desired number of steps required for player 1 to win, and the expertise
    levels of the two players. Our approach leverages symbolic methods and iterative
    simulation to efficiently search the extremely large state space. We present experimental
    results that include discovery of states of varying hardness levels for several
    simple grid-based board games. The presence of such states for standard game variants
    like 4×4 Tic-Tac-Toe opens up new games to be played that have never been played
    as the default start state is heavily biased. '
acknowledgement: "A Technical Report of this paper is available at: \r\nhttps://repository.ist.ac.at/id/eprint/146.\r\n"
article_processing_charge: No
arxiv: 1
author:
- first_name: Umair
  full_name: Ahmed, Umair
  last_name: Ahmed
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Sumit
  full_name: Gulwani, Sumit
  last_name: Gulwani
citation:
  ama: 'Ahmed U, Chatterjee K, Gulwani S. Automatic generation of alternative starting
    positions for simple traditional board games. In: <i>Proceedings of the Twenty-Ninth
    AAAI Conference on Artificial Intelligence</i>. Vol 2. AAAI Press; 2015:745-752.'
  apa: 'Ahmed, U., Chatterjee, K., &#38; Gulwani, S. (2015). Automatic generation
    of alternative starting positions for simple traditional board games. In <i>Proceedings
    of the Twenty-Ninth AAAI Conference on Artificial Intelligence</i> (Vol. 2, pp.
    745–752). Austin, TX, USA: AAAI Press.'
  chicago: Ahmed, Umair, Krishnendu Chatterjee, and Sumit Gulwani. “Automatic Generation
    of Alternative Starting Positions for Simple Traditional Board Games.” In <i>Proceedings
    of the Twenty-Ninth AAAI Conference on Artificial Intelligence</i>, 2:745–52.
    AAAI Press, 2015.
  ieee: U. Ahmed, K. Chatterjee, and S. Gulwani, “Automatic generation of alternative
    starting positions for simple traditional board games,” in <i>Proceedings of the
    Twenty-Ninth AAAI Conference on Artificial Intelligence</i>, Austin, TX, USA,
    2015, vol. 2, pp. 745–752.
  ista: 'Ahmed U, Chatterjee K, Gulwani S. 2015. Automatic generation of alternative
    starting positions for simple traditional board games. Proceedings of the Twenty-Ninth
    AAAI Conference on Artificial Intelligence. AAAI: Conference on Artificial Intelligence
    vol. 2, 745–752.'
  mla: Ahmed, Umair, et al. “Automatic Generation of Alternative Starting Positions
    for Simple Traditional Board Games.” <i>Proceedings of the Twenty-Ninth AAAI Conference
    on Artificial Intelligence</i>, vol. 2, AAAI Press, 2015, pp. 745–52.
  short: U. Ahmed, K. Chatterjee, S. Gulwani, in:, Proceedings of the Twenty-Ninth
    AAAI Conference on Artificial Intelligence, AAAI Press, 2015, pp. 745–752.
conference:
  end_date: 2015-01-30
  location: Austin, TX, USA
  name: 'AAAI: Conference on Artificial Intelligence'
  start_date: 2015-01-25
date_created: 2018-12-11T11:52:16Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2025-05-19T11:10:17Z
day: '01'
department:
- _id: KrCh
ec_funded: 1
external_id:
  arxiv:
  - '1411.4023'
intvolume: '         2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.aaai.org/ocs/index.php/AAAI/AAAI15/paper/download/9523/9300
month: '01'
oa: 1
oa_version: None
page: 745 - 752
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P 23499-N23
  name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '279307'
  name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2587B514-B435-11E9-9278-68D0E5697425
  name: Microsoft Research Faculty Fellowship
publication: Proceedings of the Twenty-Ninth AAAI Conference on Artificial Intelligence
publication_status: published
publisher: AAAI Press
publist_id: '5713'
quality_controlled: '1'
related_material:
  record:
  - id: '5410'
    relation: earlier_version
    status: public
scopus_import: '1'
status: public
title: Automatic generation of alternative starting positions for simple traditional
  board games
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2
year: '2015'
...
---
_id: '1483'
abstract:
- lang: eng
  text: Topological data analysis offers a rich source of valuable information to
    study vision problems. Yet, so far we lack a theoretically sound connection to
    popular kernel-based learning techniques, such as kernel SVMs or kernel PCA. In
    this work, we establish such a connection by designing a multi-scale kernel for
    persistence diagrams, a stable summary representation of topological features
    in data. We show that this kernel is positive definite and prove its stability
    with respect to the 1-Wasserstein distance. Experiments on two benchmark datasets
    for 3D shape classification/retrieval and texture recognition show considerable
    performance gains of the proposed method compared to an alternative approach that
    is based on the recently introduced persistence landscapes.
article_processing_charge: No
arxiv: 1
author:
- first_name: Jan
  full_name: Reininghaus, Jan
  id: 4505473A-F248-11E8-B48F-1D18A9856A87
  last_name: Reininghaus
- first_name: Stefan
  full_name: Huber, Stefan
  id: 4700A070-F248-11E8-B48F-1D18A9856A87
  last_name: Huber
  orcid: 0000-0002-8871-5814
- first_name: Ulrich
  full_name: Bauer, Ulrich
  id: 2ADD483A-F248-11E8-B48F-1D18A9856A87
  last_name: Bauer
  orcid: 0000-0002-9683-0724
- first_name: Roland
  full_name: Kwitt, Roland
  last_name: Kwitt
citation:
  ama: 'Reininghaus J, Huber S, Bauer U, Kwitt R. A stable multi-scale kernel for
    topological machine learning. In: IEEE; 2015:4741-4748. doi:<a href="https://doi.org/10.1109/CVPR.2015.7299106">10.1109/CVPR.2015.7299106</a>'
  apa: 'Reininghaus, J., Huber, S., Bauer, U., &#38; Kwitt, R. (2015). A stable multi-scale
    kernel for topological machine learning (pp. 4741–4748). Presented at the CVPR:
    Computer Vision and Pattern Recognition, Boston, MA, USA: IEEE. <a href="https://doi.org/10.1109/CVPR.2015.7299106">https://doi.org/10.1109/CVPR.2015.7299106</a>'
  chicago: Reininghaus, Jan, Stefan Huber, Ulrich Bauer, and Roland Kwitt. “A Stable
    Multi-Scale Kernel for Topological Machine Learning,” 4741–48. IEEE, 2015. <a
    href="https://doi.org/10.1109/CVPR.2015.7299106">https://doi.org/10.1109/CVPR.2015.7299106</a>.
  ieee: 'J. Reininghaus, S. Huber, U. Bauer, and R. Kwitt, “A stable multi-scale kernel
    for topological machine learning,” presented at the CVPR: Computer Vision and
    Pattern Recognition, Boston, MA, USA, 2015, pp. 4741–4748.'
  ista: 'Reininghaus J, Huber S, Bauer U, Kwitt R. 2015. A stable multi-scale kernel
    for topological machine learning. CVPR: Computer Vision and Pattern Recognition,
    4741–4748.'
  mla: Reininghaus, Jan, et al. <i>A Stable Multi-Scale Kernel for Topological Machine
    Learning</i>. IEEE, 2015, pp. 4741–48, doi:<a href="https://doi.org/10.1109/CVPR.2015.7299106">10.1109/CVPR.2015.7299106</a>.
  short: J. Reininghaus, S. Huber, U. Bauer, R. Kwitt, in:, IEEE, 2015, pp. 4741–4748.
conference:
  end_date: 2015-06-12
  location: Boston, MA, USA
  name: 'CVPR: Computer Vision and Pattern Recognition'
  start_date: 2015-06-07
date_created: 2018-12-11T11:52:17Z
date_published: 2015-10-14T00:00:00Z
date_updated: 2025-06-11T06:37:43Z
day: '14'
department:
- _id: HeEd
doi: 10.1109/CVPR.2015.7299106
external_id:
  arxiv:
  - '1412.6821'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://arxiv.org/abs/1412.6821
month: '10'
oa: 1
oa_version: Preprint
page: 4741 - 4748
publication_identifier:
  eisbn:
  - '978-1-4673-6964-0 '
publication_status: published
publisher: IEEE
publist_id: '5709'
scopus_import: '1'
status: public
title: A stable multi-scale kernel for topological machine learning
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '1495'
abstract:
- lang: eng
  text: 'Motivated by biological questions, we study configurations of equal-sized
    disks in the Euclidean plane that neither pack nor cover. Measuring the quality
    by the probability that a random point lies in exactly one disk, we show that
    the regular hexagonal grid gives the maximum among lattice configurations. '
article_processing_charge: No
arxiv: 1
author:
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
- first_name: Mabel
  full_name: Iglesias Ham, Mabel
  id: 41B58C0C-F248-11E8-B48F-1D18A9856A87
  last_name: Iglesias Ham
- first_name: Vitaliy
  full_name: Kurlin, Vitaliy
  last_name: Kurlin
citation:
  ama: 'Edelsbrunner H, Iglesias Ham M, Kurlin V. Relaxed disk packing. In: <i>Proceedings
    of the 27th Canadian Conference on Computational Geometry</i>. Vol 2015-August.
    Queen’s University; 2015:128-135.'
  apa: 'Edelsbrunner, H., Iglesias Ham, M., &#38; Kurlin, V. (2015). Relaxed disk
    packing. In <i>Proceedings of the 27th Canadian Conference on Computational Geometry</i>
    (Vol. 2015–August, pp. 128–135). Ontario, Canada: Queen’s University.'
  chicago: Edelsbrunner, Herbert, Mabel Iglesias Ham, and Vitaliy Kurlin. “Relaxed
    Disk Packing.” In <i>Proceedings of the 27th Canadian Conference on Computational
    Geometry</i>, 2015–August:128–35. Queen’s University, 2015.
  ieee: H. Edelsbrunner, M. Iglesias Ham, and V. Kurlin, “Relaxed disk packing,” in
    <i>Proceedings of the 27th Canadian Conference on Computational Geometry</i>,
    Ontario, Canada, 2015, vol. 2015–August, pp. 128–135.
  ista: 'Edelsbrunner H, Iglesias Ham M, Kurlin V. 2015. Relaxed disk packing. Proceedings
    of the 27th Canadian Conference on Computational Geometry. CCCG: Canadian Conference
    on Computational Geometry vol. 2015–August, 128–135.'
  mla: Edelsbrunner, Herbert, et al. “Relaxed Disk Packing.” <i>Proceedings of the
    27th Canadian Conference on Computational Geometry</i>, vol. 2015–August, Queen’s
    University, 2015, pp. 128–35.
  short: H. Edelsbrunner, M. Iglesias Ham, V. Kurlin, in:, Proceedings of the 27th
    Canadian Conference on Computational Geometry, Queen’s University, 2015, pp. 128–135.
conference:
  end_date: 2015-08-12
  location: Ontario, Canada
  name: 'CCCG: Canadian Conference on Computational Geometry'
  start_date: 2015-08-10
date_created: 2018-12-11T11:52:21Z
date_published: 2015-08-01T00:00:00Z
date_updated: 2025-06-11T06:38:01Z
day: '01'
department:
- _id: HeEd
ec_funded: 1
external_id:
  arxiv:
  - '1505.03402'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1505.03402
month: '08'
oa: 1
oa_version: Submitted Version
page: 128-135
project:
- _id: 255D761E-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '318493'
  name: Topological Complex Systems
publication: Proceedings of the 27th Canadian Conference on Computational Geometry
publication_status: published
publisher: Queen's University
publist_id: '5684'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Relaxed disk packing
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2015-August
year: '2015'
...
---
_id: '1497'
abstract:
- lang: eng
  text: Detecting allelic biases from high-throughput sequencing data requires an
    approach that maximises sensitivity while minimizing false positives. Here, we
    present Allelome.PRO, an automated user-friendly bioinformatics pipeline, which
    uses high-throughput sequencing data from reciprocal crosses of two genetically
    distinct mouse strains to detect allele-specific expression and chromatin modifications.
    Allelome.PRO extends approaches used in previous studies that exclusively analyzed
    imprinted expression to give a complete picture of the ‘allelome’ by automatically
    categorising the allelic expression of all genes in a given cell type into imprinted,
    strain-biased, biallelic or non-informative. Allelome.PRO offers increased sensitivity
    to analyze lowly expressed transcripts, together with a robust false discovery
    rate empirically calculated from variation in the sequencing data. We used RNA-seq
    data from mouse embryonic fibroblasts from F1 reciprocal crosses to determine
    a biologically relevant allelic ratio cutoff, and define for the first time an
    entire allelome. Furthermore, we show that Allelome.PRO detects differential enrichment
    of H3K4me3 over promoters from ChIP-seq data validating the RNA-seq results. This
    approach can be easily extended to analyze histone marks of active enhancers,
    or transcription factor binding sites and therefore provides a powerful tool to
    identify candidate cis regulatory elements genome wide.
acknowledgement: "Austrian Science Fund [FWF P25185-B22, FWF F4302- B09, FWFW1207-B09].
  Funding for open access charge: Austrian Science Fund.\r\nWe thank Florian Breitwieser
  for advice during the early stages of this project. High-throughput sequencing was
  conducted by the Biomedical Sequencing Facility (BSF) at CeMM in Vienna."
article_number: e146
article_processing_charge: No
author:
- first_name: Daniel
  full_name: Andergassen, Daniel
  last_name: Andergassen
- first_name: Christoph
  full_name: Dotter, Christoph
  id: 4C66542E-F248-11E8-B48F-1D18A9856A87
  last_name: Dotter
  orcid: 0000-0002-9033-9096
- first_name: Tomasz
  full_name: Kulinski, Tomasz
  last_name: Kulinski
- first_name: Philipp
  full_name: Guenzl, Philipp
  last_name: Guenzl
- first_name: Philipp
  full_name: Bammer, Philipp
  last_name: Bammer
- first_name: Denise
  full_name: Barlow, Denise
  last_name: Barlow
- first_name: Florian
  full_name: Pauler, Florian
  last_name: Pauler
- first_name: Quanah
  full_name: Hudson, Quanah
  last_name: Hudson
citation:
  ama: Andergassen D, Dotter C, Kulinski T, et al. Allelome.PRO, a pipeline to define
    allele-specific genomic features from high-throughput sequencing data. <i>Nucleic
    Acids Research</i>. 2015;43(21). doi:<a href="https://doi.org/10.1093/nar/gkv727">10.1093/nar/gkv727</a>
  apa: Andergassen, D., Dotter, C., Kulinski, T., Guenzl, P., Bammer, P., Barlow,
    D., … Hudson, Q. (2015). Allelome.PRO, a pipeline to define allele-specific genomic
    features from high-throughput sequencing data. <i>Nucleic Acids Research</i>.
    Oxford University Press. <a href="https://doi.org/10.1093/nar/gkv727">https://doi.org/10.1093/nar/gkv727</a>
  chicago: Andergassen, Daniel, Christoph Dotter, Tomasz Kulinski, Philipp Guenzl,
    Philipp Bammer, Denise Barlow, Florian Pauler, and Quanah Hudson. “Allelome.PRO,
    a Pipeline to Define Allele-Specific Genomic Features from High-Throughput Sequencing
    Data.” <i>Nucleic Acids Research</i>. Oxford University Press, 2015. <a href="https://doi.org/10.1093/nar/gkv727">https://doi.org/10.1093/nar/gkv727</a>.
  ieee: D. Andergassen <i>et al.</i>, “Allelome.PRO, a pipeline to define allele-specific
    genomic features from high-throughput sequencing data,” <i>Nucleic Acids Research</i>,
    vol. 43, no. 21. Oxford University Press, 2015.
  ista: Andergassen D, Dotter C, Kulinski T, Guenzl P, Bammer P, Barlow D, Pauler
    F, Hudson Q. 2015. Allelome.PRO, a pipeline to define allele-specific genomic
    features from high-throughput sequencing data. Nucleic Acids Research. 43(21),
    e146.
  mla: Andergassen, Daniel, et al. “Allelome.PRO, a Pipeline to Define Allele-Specific
    Genomic Features from High-Throughput Sequencing Data.” <i>Nucleic Acids Research</i>,
    vol. 43, no. 21, e146, Oxford University Press, 2015, doi:<a href="https://doi.org/10.1093/nar/gkv727">10.1093/nar/gkv727</a>.
  short: D. Andergassen, C. Dotter, T. Kulinski, P. Guenzl, P. Bammer, D. Barlow,
    F. Pauler, Q. Hudson, Nucleic Acids Research 43 (2015).
date_created: 2018-12-11T11:52:22Z
date_published: 2015-07-21T00:00:00Z
date_updated: 2025-09-23T07:45:31Z
day: '21'
ddc:
- '570'
department:
- _id: GaNo
doi: 10.1093/nar/gkv727
external_id:
  isi:
  - '000366410900009'
file:
- access_level: open_access
  checksum: 385b83854fd0eb2e4f386867da2823e2
  content_type: application/pdf
  creator: dernst
  date_created: 2018-12-20T14:18:57Z
  date_updated: 2020-07-14T12:44:58Z
  file_id: '5768'
  file_name: 2015_NucleicAcidsRes_Andergassen.pdf
  file_size: 6863297
  relation: main_file
file_date_updated: 2020-07-14T12:44:58Z
has_accepted_license: '1'
intvolume: '        43'
isi: 1
issue: '21'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
publication: Nucleic Acids Research
publication_status: published
publisher: Oxford University Press
publist_id: '5682'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Allelome.PRO, a pipeline to define allele-specific genomic features from high-throughput
  sequencing data
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 43
year: '2015'
...
---
_id: '1498'
abstract:
- lang: eng
  text: Fault-tolerant distributed algorithms play an important role in many critical/high-availability
    applications. These algorithms are notoriously difficult to implement correctly,
    due to asynchronous communication and the occurrence of faults, such as the network
    dropping messages or computers crashing. Nonetheless there is surprisingly little
    language and verification support to build distributed systems based on fault-tolerant
    algorithms. In this paper, we present some of the challenges that a designer has
    to overcome to implement a fault-tolerant distributed system. Then we review different
    models that have been proposed to reason about distributed algorithms and sketch
    how such a model can form the basis for a domain-specific programming language.
    Adopting a high-level programming model can simplify the programmer's life and
    make the code amenable to automated verification, while still compiling to efficiently
    executable code. We conclude by summarizing the current status of an ongoing language
    design and implementation project that is based on this idea.
alternative_title:
- LIPIcs
author:
- first_name: Cezara
  full_name: Dragoi, Cezara
  id: 2B2B5ED0-F248-11E8-B48F-1D18A9856A87
  last_name: Dragoi
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Damien
  full_name: Zufferey, Damien
  id: 4397AC76-F248-11E8-B48F-1D18A9856A87
  last_name: Zufferey
  orcid: 0000-0002-3197-8736
citation:
  ama: Dragoi C, Henzinger TA, Zufferey D. The need for language support for fault-tolerant
    distributed systems. 2015;32:90-102. doi:<a href="https://doi.org/10.4230/LIPIcs.SNAPL.2015.90">10.4230/LIPIcs.SNAPL.2015.90</a>
  apa: 'Dragoi, C., Henzinger, T. A., &#38; Zufferey, D. (2015). The need for language
    support for fault-tolerant distributed systems. Presented at the SNAPL: Summit
    oN Advances in Programming Languages, Asilomar, CA, United States: Schloss Dagstuhl
    - Leibniz-Zentrum für Informatik. <a href="https://doi.org/10.4230/LIPIcs.SNAPL.2015.90">https://doi.org/10.4230/LIPIcs.SNAPL.2015.90</a>'
  chicago: Dragoi, Cezara, Thomas A Henzinger, and Damien Zufferey. “The Need for
    Language Support for Fault-Tolerant Distributed Systems.” Leibniz International
    Proceedings in Informatics. Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
    2015. <a href="https://doi.org/10.4230/LIPIcs.SNAPL.2015.90">https://doi.org/10.4230/LIPIcs.SNAPL.2015.90</a>.
  ieee: C. Dragoi, T. A. Henzinger, and D. Zufferey, “The need for language support
    for fault-tolerant distributed systems,” vol. 32. Schloss Dagstuhl - Leibniz-Zentrum
    für Informatik, pp. 90–102, 2015.
  ista: Dragoi C, Henzinger TA, Zufferey D. 2015. The need for language support for
    fault-tolerant distributed systems. 32, 90–102.
  mla: Dragoi, Cezara, et al. <i>The Need for Language Support for Fault-Tolerant
    Distributed Systems</i>. Vol. 32, Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
    2015, pp. 90–102, doi:<a href="https://doi.org/10.4230/LIPIcs.SNAPL.2015.90">10.4230/LIPIcs.SNAPL.2015.90</a>.
  short: C. Dragoi, T.A. Henzinger, D. Zufferey, 32 (2015) 90–102.
conference:
  end_date: 2015-05-06
  location: Asilomar, CA, United States
  name: 'SNAPL: Summit oN Advances in Programming Languages'
  start_date: 2015-05-03
corr_author: '1'
date_created: 2018-12-11T11:52:22Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2025-04-15T06:26:02Z
day: '01'
ddc:
- '005'
department:
- _id: ToHe
doi: 10.4230/LIPIcs.SNAPL.2015.90
ec_funded: 1
file:
- access_level: open_access
  checksum: cf5e94baa89a2dc4c5de01abc676eda8
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:14:02Z
  date_updated: 2020-07-14T12:44:58Z
  file_id: '5050'
  file_name: IST-2016-499-v1+1_9.pdf
  file_size: 489362
  relation: main_file
file_date_updated: 2020-07-14T12:44:58Z
has_accepted_license: '1'
intvolume: '        32'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 90 - 102
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '267989'
  name: Quantitative Reactive Modeling
- _id: 25F5A88A-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S11402-N23
  name: Moderne Concurrency Paradigms
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Z211
  name: Formal methods for the design and analysis of complex systems
publication_identifier:
  isbn:
  - '978-3-939897-80-4 '
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '5681'
pubrep_id: '499'
quality_controlled: '1'
scopus_import: 1
series_title: Leibniz International Proceedings in Informatics
status: public
title: The need for language support for fault-tolerant distributed systems
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 32
year: '2015'
...
---
_id: '1499'
abstract:
- lang: eng
  text: "We consider weighted automata with both positive and negative integer weights
    on edges and\r\nstudy the problem of synchronization using adaptive strategies
    that may only observe whether\r\nthe current weight-level is negative or nonnegative.
    We show that the synchronization problem is decidable in polynomial time for deterministic
    weighted automata."
acknowledgement: "The research leading to these results has received funding from
  the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement
  601148 (CASSTING), EU FP7 FET project SENSATION, Sino-Danish Basic Research Center
  IDAE4CPS, the European Research Council (ERC) under grant agreement 267989 (QUAREM),
  the Austrian Science Fund (FWF) project S11402-N23 (RiSE) and Z211-N23 (Wittgenstein
  Award), the Czech Science Foundation under grant agreement P202/12/G061, and People
  Programme (Marie Curie Actions) of the European Union’s Seventh Framework\r\nProgramme
  (FP7/2007-2013) REA Grant No 291734."
alternative_title:
- LIPIcs
author:
- first_name: Jan
  full_name: Kretinsky, Jan
  id: 44CEF464-F248-11E8-B48F-1D18A9856A87
  last_name: Kretinsky
  orcid: 0000-0002-8122-2881
- first_name: Kim
  full_name: Larsen, Kim
  last_name: Larsen
- first_name: Simon
  full_name: Laursen, Simon
  last_name: Laursen
- first_name: Jiří
  full_name: Srba, Jiří
  last_name: Srba
citation:
  ama: 'Kretinsky J, Larsen K, Laursen S, Srba J. Polynomial time decidability of
    weighted synchronization under partial observability. In: Vol 42. Schloss Dagstuhl
    - Leibniz-Zentrum für Informatik; 2015:142-154. doi:<a href="https://doi.org/10.4230/LIPIcs.CONCUR.2015.142">10.4230/LIPIcs.CONCUR.2015.142</a>'
  apa: 'Kretinsky, J., Larsen, K., Laursen, S., &#38; Srba, J. (2015). Polynomial
    time decidability of weighted synchronization under partial observability (Vol.
    42, pp. 142–154). Presented at the CONCUR: Concurrency Theory, Madrid, Spain:
    Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href="https://doi.org/10.4230/LIPIcs.CONCUR.2015.142">https://doi.org/10.4230/LIPIcs.CONCUR.2015.142</a>'
  chicago: Kretinsky, Jan, Kim Larsen, Simon Laursen, and Jiří Srba. “Polynomial Time
    Decidability of Weighted Synchronization under Partial Observability,” 42:142–54.
    Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2015. <a href="https://doi.org/10.4230/LIPIcs.CONCUR.2015.142">https://doi.org/10.4230/LIPIcs.CONCUR.2015.142</a>.
  ieee: 'J. Kretinsky, K. Larsen, S. Laursen, and J. Srba, “Polynomial time decidability
    of weighted synchronization under partial observability,” presented at the CONCUR:
    Concurrency Theory, Madrid, Spain, 2015, vol. 42, pp. 142–154.'
  ista: 'Kretinsky J, Larsen K, Laursen S, Srba J. 2015. Polynomial time decidability
    of weighted synchronization under partial observability. CONCUR: Concurrency Theory,
    LIPIcs, vol. 42, 142–154.'
  mla: Kretinsky, Jan, et al. <i>Polynomial Time Decidability of Weighted Synchronization
    under Partial Observability</i>. Vol. 42, Schloss Dagstuhl - Leibniz-Zentrum für
    Informatik, 2015, pp. 142–54, doi:<a href="https://doi.org/10.4230/LIPIcs.CONCUR.2015.142">10.4230/LIPIcs.CONCUR.2015.142</a>.
  short: J. Kretinsky, K. Larsen, S. Laursen, J. Srba, in:, Schloss Dagstuhl - Leibniz-Zentrum
    für Informatik, 2015, pp. 142–154.
conference:
  end_date: 2015-09-04
  location: Madrid, Spain
  name: 'CONCUR: Concurrency Theory'
  start_date: 2015-09-01
date_created: 2018-12-11T11:52:22Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2025-04-15T06:26:02Z
day: '01'
ddc:
- '000'
- '003'
department:
- _id: ToHe
- _id: KrCh
doi: 10.4230/LIPIcs.CONCUR.2015.142
ec_funded: 1
file:
- access_level: open_access
  checksum: 49eb5021caafaabe5356c65b9c5f8c9c
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:08:12Z
  date_updated: 2020-07-14T12:44:58Z
  file_id: '4672'
  file_name: IST-2016-498-v1+1_32.pdf
  file_size: 623563
  relation: main_file
file_date_updated: 2020-07-14T12:44:58Z
has_accepted_license: '1'
intvolume: '        42'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 142 - 154
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '267989'
  name: Quantitative Reactive Modeling
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Z211
  name: Formal methods for the design and analysis of complex systems
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '5680'
pubrep_id: '498'
quality_controlled: '1'
scopus_import: 1
status: public
title: Polynomial time decidability of weighted synchronization under partial observability
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 42
year: '2015'
...
---
_id: '1500'
abstract:
- lang: eng
  text: In this poster, we present methods for randomly generating hybrid automata
    with affine differential equations, invariants, guards, and assignments. Selecting
    an arbitrary affine function from the set of all affine functions results in a
    low likelihood of generating hybrid automata with diverse and interesting behaviors,
    as there are an uncountable number of elements in the set of all affine functions.
    Instead, we partition the set of all affine functions into potentially interesting
    classes and randomly select elements from these classes. For example, we partition
    the set of all affine differential equations by using restrictions on eigenvalues
    such as those that yield stable, unstable, etc. equilibrium points. We partition
    the components describing discrete behavior (guards, assignments, and invariants)
    to allow either time-dependent or state-dependent switching, and in particular
    provide the ability to generate subclasses of piecewise-affine hybrid automata.
    Our preliminary experimental results with a prototype tool called HyRG (Hybrid
    Random Generator) illustrate the feasibility of this generation method to automatically
    create standard hybrid automaton examples like the bouncing ball and thermostat.
alternative_title:
- '18th ACM International Conference on Hybrid Systems: Computation and Control, HSCC
  2015'
author:
- first_name: Luan
  full_name: Nguyen, Luan V
  last_name: Nguyen
- first_name: Christian
  full_name: Christian Schilling
  id: 3A2F4DCE-F248-11E8-B48F-1D18A9856A87
  last_name: Schilling
  orcid: 0000-0003-3658-1065
- first_name: Sergiy
  full_name: Sergiy Bogomolov
  id: 369D9A44-F248-11E8-B48F-1D18A9856A87
  last_name: Bogomolov
  orcid: 0000-0002-0686-0365
- first_name: Taylor
  full_name: Johnson, Taylor T
  last_name: Johnson
citation:
  ama: 'Nguyen L, Schilling C, Bogomolov S, Johnson T. <i>Poster: HyRG: A Random Generation
    Tool for Affine Hybrid Automata</i>. Springer; 2015:289-290. doi:<a href="https://doi.org/10.1145/2728606.2728650">10.1145/2728606.2728650</a>'
  apa: 'Nguyen, L., Schilling, C., Bogomolov, S., &#38; Johnson, T. (2015). <i>Poster:
    HyRG: A random generation tool for affine hybrid automata</i>. <i>HSCC: Hybrid
    Systems - Computation and Control</i> (pp. 289–290). Springer. <a href="https://doi.org/10.1145/2728606.2728650">https://doi.org/10.1145/2728606.2728650</a>'
  chicago: 'Nguyen, Luan, Christian Schilling, Sergiy Bogomolov, and Taylor Johnson.
    <i>Poster: HyRG: A Random Generation Tool for Affine Hybrid Automata</i>. <i>HSCC:
    Hybrid Systems - Computation and Control</i>. Springer, 2015. <a href="https://doi.org/10.1145/2728606.2728650">https://doi.org/10.1145/2728606.2728650</a>.'
  ieee: 'L. Nguyen, C. Schilling, S. Bogomolov, and T. Johnson, <i>Poster: HyRG: A
    random generation tool for affine hybrid automata</i>. Springer, 2015, pp. 289–290.'
  ista: 'Nguyen L, Schilling C, Bogomolov S, Johnson T. 2015. Poster: HyRG: A random
    generation tool for affine hybrid automata, Springer,p.'
  mla: 'Nguyen, Luan, et al. “Poster: HyRG: A Random Generation Tool for Affine Hybrid
    Automata.” <i>HSCC: Hybrid Systems - Computation and Control</i>, Springer, 2015,
    pp. 289–90, doi:<a href="https://doi.org/10.1145/2728606.2728650">10.1145/2728606.2728650</a>.'
  short: 'L. Nguyen, C. Schilling, S. Bogomolov, T. Johnson, Poster: HyRG: A Random
    Generation Tool for Affine Hybrid Automata, Springer, 2015.'
date_created: 2018-12-11T11:52:23Z
date_published: 2015-04-14T00:00:00Z
date_updated: 2019-04-26T07:22:03Z
day: '14'
doi: 10.1145/2728606.2728650
extern: 1
month: '04'
page: 289 - 290
publication: 'HSCC: Hybrid Systems - Computation and Control'
publication_status: published
publisher: Springer
publist_id: '5678'
quality_controlled: 0
status: public
title: 'Poster: HyRG: A random generation tool for affine hybrid automata'
type: conference_poster
year: '2015'
...
---
_id: '1503'
abstract:
- lang: eng
  text: A Herman-Avila-Bochi type formula is obtained for the average sum of the top
    d Lyapunov exponents over a one-parameter family of double-struck G-cocycles,
    where double-struck G is the group that leaves a certain, non-degenerate Hermitian
    form of signature (c, d) invariant. The generic example of such a group is the
    pseudo-unitary group U(c, d) or, in the case c = d, the Hermitian-symplectic group
    HSp(2d) which naturally appears for cocycles related to Schrödinger operators.
    In the case d = 1, the formula for HSp(2d) cocycles reduces to the Herman-Avila-Bochi
    formula for SL(2, ℝ) cocycles.
article_processing_charge: No
author:
- first_name: Christian
  full_name: Sadel, Christian
  id: 4760E9F8-F248-11E8-B48F-1D18A9856A87
  last_name: Sadel
  orcid: 0000-0001-8255-3968
citation:
  ama: Sadel C. A Herman-Avila-Bochi formula for higher-dimensional pseudo-unitary
    and Hermitian-symplectic-cocycles. <i>Ergodic Theory and Dynamical Systems</i>.
    2015;35(5):1582-1591. doi:<a href="https://doi.org/10.1017/etds.2013.103">10.1017/etds.2013.103</a>
  apa: Sadel, C. (2015). A Herman-Avila-Bochi formula for higher-dimensional pseudo-unitary
    and Hermitian-symplectic-cocycles. <i>Ergodic Theory and Dynamical Systems</i>.
    Cambridge University Press. <a href="https://doi.org/10.1017/etds.2013.103">https://doi.org/10.1017/etds.2013.103</a>
  chicago: Sadel, Christian. “A Herman-Avila-Bochi Formula for Higher-Dimensional
    Pseudo-Unitary and Hermitian-Symplectic-Cocycles.” <i>Ergodic Theory and Dynamical
    Systems</i>. Cambridge University Press, 2015. <a href="https://doi.org/10.1017/etds.2013.103">https://doi.org/10.1017/etds.2013.103</a>.
  ieee: C. Sadel, “A Herman-Avila-Bochi formula for higher-dimensional pseudo-unitary
    and Hermitian-symplectic-cocycles,” <i>Ergodic Theory and Dynamical Systems</i>,
    vol. 35, no. 5. Cambridge University Press, pp. 1582–1591, 2015.
  ista: Sadel C. 2015. A Herman-Avila-Bochi formula for higher-dimensional pseudo-unitary
    and Hermitian-symplectic-cocycles. Ergodic Theory and Dynamical Systems. 35(5),
    1582–1591.
  mla: Sadel, Christian. “A Herman-Avila-Bochi Formula for Higher-Dimensional Pseudo-Unitary
    and Hermitian-Symplectic-Cocycles.” <i>Ergodic Theory and Dynamical Systems</i>,
    vol. 35, no. 5, Cambridge University Press, 2015, pp. 1582–91, doi:<a href="https://doi.org/10.1017/etds.2013.103">10.1017/etds.2013.103</a>.
  short: C. Sadel, Ergodic Theory and Dynamical Systems 35 (2015) 1582–1591.
date_created: 2018-12-11T11:52:24Z
date_published: 2015-03-14T00:00:00Z
date_updated: 2025-09-22T14:31:00Z
day: '14'
doi: 10.1017/etds.2013.103
extern: '1'
external_id:
  isi:
  - '000357605900010'
intvolume: '        35'
isi: 1
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1307.8414
month: '03'
oa: 1
oa_version: Preprint
page: 1582 - 1591
publication: Ergodic Theory and Dynamical Systems
publication_status: published
publisher: Cambridge University Press
publist_id: '5675'
quality_controlled: '1'
status: public
title: A Herman-Avila-Bochi formula for higher-dimensional pseudo-unitary and Hermitian-symplectic-cocycles
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 35
year: '2015'
...
---
_id: '1504'
abstract:
- lang: eng
  text: Let Q = (Q1, . . . , Qn) be a random vector drawn from the uniform distribution
    on the set of all n! permutations of {1, 2, . . . , n}. Let Z = (Z1, . . . , Zn),
    where Zj is the mean zero variance one random variable obtained by centralizing
    and normalizing Qj , j = 1, . . . , n. Assume that Xi , i = 1, . . . ,p are i.i.d.
    copies of 1/√ p Z and X = Xp,n is the p × n random matrix with Xi as its ith row.
    Then Sn = XX is called the p × n Spearman's rank correlation matrix which can
    be regarded as a high dimensional extension of the classical nonparametric statistic
    Spearman's rank correlation coefficient between two independent random variables.
    In this paper, we establish a CLT for the linear spectral statistics of this nonparametric
    random matrix model in the scenario of high dimension, namely, p = p(n) and p/n→c
    ∈ (0,∞) as n→∞.We propose a novel evaluation scheme to estimate the core quantity
    in Anderson and Zeitouni's cumulant method in [Ann. Statist. 36 (2008) 2553-2576]
    to bypass the so-called joint cumulant summability. In addition, we raise a two-step
    comparison approach to obtain the explicit formulae for the mean and covariance
    functions in the CLT. Relying on this CLT, we then construct a distribution-free
    statistic to test complete independence for components of random vectors. Owing
    to the nonparametric property, we can use this test on generally distributed random
    variables including the heavy-tailed ones.
article_processing_charge: No
author:
- first_name: Zhigang
  full_name: Bao, Zhigang
  id: 442E6A6C-F248-11E8-B48F-1D18A9856A87
  last_name: Bao
  orcid: 0000-0003-3036-1475
- first_name: Liang
  full_name: Lin, Liang
  last_name: Lin
- first_name: Guangming
  full_name: Pan, Guangming
  last_name: Pan
- first_name: Wang
  full_name: Zhou, Wang
  last_name: Zhou
citation:
  ama: Bao Z, Lin L, Pan G, Zhou W. Spectral statistics of large dimensional spearman
    s rank correlation matrix and its application. <i>Annals of Statistics</i>. 2015;43(6):2588-2623.
    doi:<a href="https://doi.org/10.1214/15-AOS1353">10.1214/15-AOS1353</a>
  apa: Bao, Z., Lin, L., Pan, G., &#38; Zhou, W. (2015). Spectral statistics of large
    dimensional spearman s rank correlation matrix and its application. <i>Annals
    of Statistics</i>. Institute of Mathematical Statistics. <a href="https://doi.org/10.1214/15-AOS1353">https://doi.org/10.1214/15-AOS1353</a>
  chicago: Bao, Zhigang, Liang Lin, Guangming Pan, and Wang Zhou. “Spectral Statistics
    of Large Dimensional Spearman s Rank Correlation Matrix and Its Application.”
    <i>Annals of Statistics</i>. Institute of Mathematical Statistics, 2015. <a href="https://doi.org/10.1214/15-AOS1353">https://doi.org/10.1214/15-AOS1353</a>.
  ieee: Z. Bao, L. Lin, G. Pan, and W. Zhou, “Spectral statistics of large dimensional
    spearman s rank correlation matrix and its application,” <i>Annals of Statistics</i>,
    vol. 43, no. 6. Institute of Mathematical Statistics, pp. 2588–2623, 2015.
  ista: Bao Z, Lin L, Pan G, Zhou W. 2015. Spectral statistics of large dimensional
    spearman s rank correlation matrix and its application. Annals of Statistics.
    43(6), 2588–2623.
  mla: Bao, Zhigang, et al. “Spectral Statistics of Large Dimensional Spearman s Rank
    Correlation Matrix and Its Application.” <i>Annals of Statistics</i>, vol. 43,
    no. 6, Institute of Mathematical Statistics, 2015, pp. 2588–623, doi:<a href="https://doi.org/10.1214/15-AOS1353">10.1214/15-AOS1353</a>.
  short: Z. Bao, L. Lin, G. Pan, W. Zhou, Annals of Statistics 43 (2015) 2588–2623.
date_created: 2018-12-11T11:52:24Z
date_published: 2015-12-01T00:00:00Z
date_updated: 2025-09-23T10:47:55Z
day: '01'
doi: 10.1214/15-AOS1353
extern: '1'
external_id:
  isi:
  - '000363437900010'
intvolume: '        43'
isi: 1
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1312.5119
month: '12'
oa: 1
oa_version: Published Version
page: 2588 - 2623
publication: Annals of Statistics
publication_status: published
publisher: Institute of Mathematical Statistics
publist_id: '5674'
quality_controlled: '1'
status: public
title: Spectral statistics of large dimensional spearman s rank correlation matrix
  and its application
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 43
year: '2015'
...
---
_id: '1505'
abstract:
- lang: eng
  text: This paper is aimed at deriving the universality of the largest eigenvalue
    of a class of high-dimensional real or complex sample covariance matrices of the
    form W N =Σ 1/2XX∗Σ 1/2 . Here, X = (xij )M,N is an M× N random matrix with independent
    entries xij , 1 ≤ i M,≤ 1 ≤ j ≤ N such that Exij = 0, E|xij |2 = 1/N . On dimensionality,
    we assume that M = M(N) and N/M → d ε (0, ∞) as N ∞→. For a class of general deterministic
    positive-definite M × M matrices Σ , under some additional assumptions on the
    distribution of xij 's, we show that the limiting behavior of the largest eigenvalue
    of W N is universal, via pursuing a Green function comparison strategy raised
    in [Probab. Theory Related Fields 154 (2012) 341-407, Adv. Math. 229 (2012) 1435-1515]
    by Erd″os, Yau and Yin for Wigner matrices and extended by Pillai and Yin [Ann.
    Appl. Probab. 24 (2014) 935-1001] to sample covariance matrices in the null case
    (&amp;Epsi = I ). Consequently, in the standard complex case (Ex2 ij = 0), combing
    this universality property and the results known for Gaussian matrices obtained
    by El Karoui in [Ann. Probab. 35 (2007) 663-714] (nonsingular case) and Onatski
    in [Ann. Appl. Probab. 18 (2008) 470-490] (singular case), we show that after
    an appropriate normalization the largest eigenvalue of W N converges weakly to
    the type 2 Tracy-Widom distribution TW2 . Moreover, in the real case, we show
    that whenΣ is spiked with a fixed number of subcritical spikes, the type 1 Tracy-Widom
    limit TW1 holds for the normalized largest eigenvalue of W N , which extends a
    result of Féral and Péché in [J. Math. Phys. 50 (2009) 073302] to the scenario
    of nondiagonal Σ and more generally distributed X . In summary, we establish the
    Tracy-Widom type universality for the largest eigenvalue of generally distributed
    sample covariance matrices under quite light assumptions on &amp;Sigma . Applications
    of these limiting results to statistical signal detection and structure recognition
    of separable covariance matrices are also discussed.
acknowledgement: "B.Z. was supported  in  part  by  NSFC  Grant  11071213,  ZJNSF
  \ Grant  R6090034  and  SRFDP  Grant 20100101110001. P.G. was supported in part
  by the Ministry of Education, Singapore, under Grant ARC 14/11. Z.W. was supported
  \ in  part  by  the  Ministry  of  Education,  Singapore,  under  Grant  ARC  14/11,
  \ and  by a Grant R-155-000-131-112 at the National University of Singapore\r\n"
article_processing_charge: No
arxiv: 1
author:
- first_name: Zhigang
  full_name: Bao, Zhigang
  id: 442E6A6C-F248-11E8-B48F-1D18A9856A87
  last_name: Bao
  orcid: 0000-0003-3036-1475
- first_name: Guangming
  full_name: Pan, Guangming
  last_name: Pan
- first_name: Wang
  full_name: Zhou, Wang
  last_name: Zhou
citation:
  ama: Bao Z, Pan G, Zhou W. Universality for the largest eigenvalue of sample covariance
    matrices with general population. <i>Annals of Statistics</i>. 2015;43(1):382-421.
    doi:<a href="https://doi.org/10.1214/14-AOS1281">10.1214/14-AOS1281</a>
  apa: Bao, Z., Pan, G., &#38; Zhou, W. (2015). Universality for the largest eigenvalue
    of sample covariance matrices with general population. <i>Annals of Statistics</i>.
    Institute of Mathematical Statistics. <a href="https://doi.org/10.1214/14-AOS1281">https://doi.org/10.1214/14-AOS1281</a>
  chicago: Bao, Zhigang, Guangming Pan, and Wang Zhou. “Universality for the Largest
    Eigenvalue of Sample Covariance Matrices with General Population.” <i>Annals of
    Statistics</i>. Institute of Mathematical Statistics, 2015. <a href="https://doi.org/10.1214/14-AOS1281">https://doi.org/10.1214/14-AOS1281</a>.
  ieee: Z. Bao, G. Pan, and W. Zhou, “Universality for the largest eigenvalue of sample
    covariance matrices with general population,” <i>Annals of Statistics</i>, vol.
    43, no. 1. Institute of Mathematical Statistics, pp. 382–421, 2015.
  ista: Bao Z, Pan G, Zhou W. 2015. Universality for the largest eigenvalue of sample
    covariance matrices with general population. Annals of Statistics. 43(1), 382–421.
  mla: Bao, Zhigang, et al. “Universality for the Largest Eigenvalue of Sample Covariance
    Matrices with General Population.” <i>Annals of Statistics</i>, vol. 43, no. 1,
    Institute of Mathematical Statistics, 2015, pp. 382–421, doi:<a href="https://doi.org/10.1214/14-AOS1281">10.1214/14-AOS1281</a>.
  short: Z. Bao, G. Pan, W. Zhou, Annals of Statistics 43 (2015) 382–421.
date_created: 2018-12-11T11:52:25Z
date_published: 2015-02-01T00:00:00Z
date_updated: 2025-09-29T11:02:34Z
day: '01'
department:
- _id: LaEr
doi: 10.1214/14-AOS1281
external_id:
  arxiv:
  - '1304.5690'
  isi:
  - '000349738500014'
intvolume: '        43'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1304.5690
month: '02'
oa: 1
oa_version: Preprint
page: 382 - 421
publication: Annals of Statistics
publication_status: published
publisher: Institute of Mathematical Statistics
publist_id: '5672'
quality_controlled: '1'
status: public
title: Universality for the largest eigenvalue of sample covariance matrices with
  general population
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 43
year: '2015'
...
---
_id: '1506'
abstract:
- lang: eng
  text: Consider the square random matrix An = (aij)n,n, where {aij:= a(n)ij , i,
    j = 1, . . . , n} is a collection of independent real random variables with means
    zero and variances one. Under the additional moment condition supn max1≤i,j ≤n
    Ea4ij &lt;∞, we prove Girko's logarithmic law of det An in the sense that as n→∞
    log | detAn| ? (1/2) log(n-1)! d/→√(1/2) log n N(0, 1).
article_processing_charge: No
arxiv: 1
author:
- first_name: Zhigang
  full_name: Bao, Zhigang
  id: 442E6A6C-F248-11E8-B48F-1D18A9856A87
  last_name: Bao
  orcid: 0000-0003-3036-1475
- first_name: Guangming
  full_name: Pan, Guangming
  last_name: Pan
- first_name: Wang
  full_name: Zhou, Wang
  last_name: Zhou
citation:
  ama: Bao Z, Pan G, Zhou W. The logarithmic law of random determinant. <i>Bernoulli</i>.
    2015;21(3):1600-1628. doi:<a href="https://doi.org/10.3150/14-BEJ615">10.3150/14-BEJ615</a>
  apa: Bao, Z., Pan, G., &#38; Zhou, W. (2015). The logarithmic law of random determinant.
    <i>Bernoulli</i>. Bernoulli Society for Mathematical Statistics and Probability.
    <a href="https://doi.org/10.3150/14-BEJ615">https://doi.org/10.3150/14-BEJ615</a>
  chicago: Bao, Zhigang, Guangming Pan, and Wang Zhou. “The Logarithmic Law of Random
    Determinant.” <i>Bernoulli</i>. Bernoulli Society for Mathematical Statistics
    and Probability, 2015. <a href="https://doi.org/10.3150/14-BEJ615">https://doi.org/10.3150/14-BEJ615</a>.
  ieee: Z. Bao, G. Pan, and W. Zhou, “The logarithmic law of random determinant,”
    <i>Bernoulli</i>, vol. 21, no. 3. Bernoulli Society for Mathematical Statistics
    and Probability, pp. 1600–1628, 2015.
  ista: Bao Z, Pan G, Zhou W. 2015. The logarithmic law of random determinant. Bernoulli.
    21(3), 1600–1628.
  mla: Bao, Zhigang, et al. “The Logarithmic Law of Random Determinant.” <i>Bernoulli</i>,
    vol. 21, no. 3, Bernoulli Society for Mathematical Statistics and Probability,
    2015, pp. 1600–28, doi:<a href="https://doi.org/10.3150/14-BEJ615">10.3150/14-BEJ615</a>.
  short: Z. Bao, G. Pan, W. Zhou, Bernoulli 21 (2015) 1600–1628.
date_created: 2018-12-11T11:52:25Z
date_published: 2015-08-01T00:00:00Z
date_updated: 2025-09-23T13:59:56Z
day: '01'
department:
- _id: LaEr
doi: 10.3150/14-BEJ615
external_id:
  arxiv:
  - '1208.5823'
  isi:
  - '000356993100012'
intvolume: '        21'
isi: 1
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://arxiv.org/abs/1208.5823
month: '08'
oa: 1
oa_version: Preprint
page: 1600 - 1628
publication: Bernoulli
publication_status: published
publisher: Bernoulli Society for Mathematical Statistics and Probability
publist_id: '5671'
quality_controlled: '1'
status: public
title: The logarithmic law of random determinant
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 21
year: '2015'
...
---
_id: '1508'
abstract:
- lang: eng
  text: We consider generalized Wigner ensembles and general β-ensembles with analytic
    potentials for any β ≥ 1. The recent universality results in particular assert
    that the local averages of consecutive eigenvalue gaps in the bulk of the spectrum
    are universal in the sense that they coincide with those of the corresponding
    Gaussian β-ensembles. In this article, we show that local averaging is not necessary
    for this result, i.e. we prove that the single gap distributions in the bulk are
    universal. In fact, with an additional step, our result can be extended to any
    C4(ℝ) potential.
article_processing_charge: No
arxiv: 1
author:
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
- first_name: Horng
  full_name: Yau, Horng
  last_name: Yau
citation:
  ama: Erdös L, Yau H. Gap universality of generalized Wigner and β ensembles. <i>Journal
    of the European Mathematical Society</i>. 2015;17(8):1927-2036. doi:<a href="https://doi.org/10.4171/JEMS/548">10.4171/JEMS/548</a>
  apa: Erdös, L., &#38; Yau, H. (2015). Gap universality of generalized Wigner and
    β ensembles. <i>Journal of the European Mathematical Society</i>. European Mathematical
    Society. <a href="https://doi.org/10.4171/JEMS/548">https://doi.org/10.4171/JEMS/548</a>
  chicago: Erdös, László, and Horng Yau. “Gap Universality of Generalized Wigner and
    β Ensembles.” <i>Journal of the European Mathematical Society</i>. European Mathematical
    Society, 2015. <a href="https://doi.org/10.4171/JEMS/548">https://doi.org/10.4171/JEMS/548</a>.
  ieee: L. Erdös and H. Yau, “Gap universality of generalized Wigner and β ensembles,”
    <i>Journal of the European Mathematical Society</i>, vol. 17, no. 8. European
    Mathematical Society, pp. 1927–2036, 2015.
  ista: Erdös L, Yau H. 2015. Gap universality of generalized Wigner and β ensembles.
    Journal of the European Mathematical Society. 17(8), 1927–2036.
  mla: Erdös, László, and Horng Yau. “Gap Universality of Generalized Wigner and β
    Ensembles.” <i>Journal of the European Mathematical Society</i>, vol. 17, no.
    8, European Mathematical Society, 2015, pp. 1927–2036, doi:<a href="https://doi.org/10.4171/JEMS/548">10.4171/JEMS/548</a>.
  short: L. Erdös, H. Yau, Journal of the European Mathematical Society 17 (2015)
    1927–2036.
date_created: 2018-12-11T11:52:26Z
date_published: 2015-08-01T00:00:00Z
date_updated: 2025-09-23T09:08:38Z
day: '01'
department:
- _id: LaEr
doi: 10.4171/JEMS/548
external_id:
  arxiv:
  - '1211.3786'
  isi:
  - '000360822900003'
intvolume: '        17'
isi: 1
issue: '8'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://arxiv.org/abs/1211.3786
month: '08'
oa: 1
oa_version: Preprint
page: 1927 - 2036
publication: Journal of the European Mathematical Society
publication_status: published
publisher: European Mathematical Society
publist_id: '5669'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Gap universality of generalized Wigner and β ensembles
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 17
year: '2015'
...
---
_id: '1509'
abstract:
- lang: eng
  text: The Auxin Binding Protein1 (ABP1) has been identified based on its ability
    to bind auxin with high affinity and studied for a long time as a prime candidate
    for the extracellular auxin receptor responsible for mediating in particular the
    fast non-transcriptional auxin responses. However, the contradiction between the
    embryo-lethal phenotypes of the originally described Arabidopsis T-DNA insertional
    knock-out alleles (abp1-1 and abp1-1s) and the wild type-like phenotypes of other
    recently described loss-of-function alleles (abp1-c1 and abp1-TD1) questions the
    biological importance of ABP1 and relevance of the previous genetic studies. Here
    we show that there is no hidden copy of the ABP1 gene in the Arabidopsis genome
    but the embryo-lethal phenotypes of abp1-1 and abp1-1s alleles are very similar
    to the knock-out phenotypes of the neighboring gene, BELAYA SMERT (BSM). Furthermore,
    the allelic complementation test between bsm and abp1 alleles shows that the embryo-lethality
    in the abp1-1 and abp1-1s alleles is caused by the off-target disruption of the
    BSM locus by the T-DNA insertions. This clarifies the controversy of different
    phenotypes among published abp1 knock-out alleles and asks for reflections on
    the developmental role of ABP1.
acknowledgement: "This work was supported by ERC Independent Research grant (ERC-2011-StG-20101109-PSDP
  to JF). JM internship was supported by the grant “Action Austria – Slovakia”.\r\nData
  associated with the article are available under the terms of the Creative Commons
  Zero \"No rights reserved\" data waiver (CC0 1.0 Public domain dedication). \r\n\r\nData
  availability: \r\nF1000Research: Dataset 1. Dataset 1, 10.5256/f1000research.7143.d104552\r\n\r\nF1000Research:
  Dataset 2. Dataset 2, 10.5256/f1000research.7143.d104553\r\n\r\nF1000Research: Dataset
  3. Dataset 3, 10.5256/f1000research.7143.d104554"
article_processing_charge: No
author:
- first_name: Jaroslav
  full_name: Michalko, Jaroslav
  id: 483727CA-F248-11E8-B48F-1D18A9856A87
  last_name: Michalko
- first_name: Marta
  full_name: Dravecka, Marta
  id: 4342E402-F248-11E8-B48F-1D18A9856A87
  last_name: Dravecka
  orcid: 0000-0002-2519-8004
- first_name: Tobias
  full_name: Bollenbach, Tobias
  id: 3E6DB97A-F248-11E8-B48F-1D18A9856A87
  last_name: Bollenbach
  orcid: 0000-0003-4398-476X
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Michalko J, Lukacisinova M, Bollenbach MT, Friml J. Embryo-lethal phenotypes
    in early abp1 mutants are due to disruption of the neighboring BSM gene. <i>F1000
    Research </i>. 2015;4. doi:<a href="https://doi.org/10.12688/f1000research.7143.1">10.12688/f1000research.7143.1</a>
  apa: Michalko, J., Lukacisinova, M., Bollenbach, M. T., &#38; Friml, J. (2015).
    Embryo-lethal phenotypes in early abp1 mutants are due to disruption of the neighboring
    BSM gene. <i>F1000 Research </i>. F1000 Research. <a href="https://doi.org/10.12688/f1000research.7143.1">https://doi.org/10.12688/f1000research.7143.1</a>
  chicago: Michalko, Jaroslav, Marta Lukacisinova, Mark Tobias Bollenbach, and Jiří
    Friml. “Embryo-Lethal Phenotypes in Early Abp1 Mutants Are Due to Disruption of
    the Neighboring BSM Gene.” <i>F1000 Research </i>. F1000 Research, 2015. <a href="https://doi.org/10.12688/f1000research.7143.1">https://doi.org/10.12688/f1000research.7143.1</a>.
  ieee: J. Michalko, M. Lukacisinova, M. T. Bollenbach, and J. Friml, “Embryo-lethal
    phenotypes in early abp1 mutants are due to disruption of the neighboring BSM
    gene,” <i>F1000 Research </i>, vol. 4. F1000 Research, 2015.
  ista: Michalko J, Lukacisinova M, Bollenbach MT, Friml J. 2015. Embryo-lethal phenotypes
    in early abp1 mutants are due to disruption of the neighboring BSM gene. F1000
    Research . 4.
  mla: Michalko, Jaroslav, et al. “Embryo-Lethal Phenotypes in Early Abp1 Mutants
    Are Due to Disruption of the Neighboring BSM Gene.” <i>F1000 Research </i>, vol.
    4, F1000 Research, 2015, doi:<a href="https://doi.org/10.12688/f1000research.7143.1">10.12688/f1000research.7143.1</a>.
  short: J. Michalko, M. Lukacisinova, M.T. Bollenbach, J. Friml, F1000 Research  4
    (2015).
corr_author: '1'
date_created: 2018-12-11T11:52:26Z
date_published: 2015-10-01T00:00:00Z
date_updated: 2025-04-15T07:48:03Z
day: '01'
ddc:
- '570'
department:
- _id: JiFr
- _id: ToBo
doi: 10.12688/f1000research.7143.1
ec_funded: 1
file:
- access_level: open_access
  checksum: 8beae5cbe988e1060265ae7de2ee8306
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:16:12Z
  date_updated: 2020-07-14T12:44:59Z
  file_id: '5198'
  file_name: IST-2016-497-v1+1_10.12688_f1000research.7143.1_20151102.pdf
  file_size: 4414248
  relation: main_file
file_date_updated: 2020-07-14T12:44:59Z
has_accepted_license: '1'
intvolume: '         4'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '282300'
  name: Polarity and subcellular dynamics in plants
publication: 'F1000 Research '
publication_status: published
publisher: F1000 Research
publist_id: '5668'
pubrep_id: '497'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Embryo-lethal phenotypes in early abp1 mutants are due to disruption of the
  neighboring BSM gene
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 4
year: '2015'
...
---
_id: '1510'
abstract:
- lang: eng
  text: 'The concept of well group in a special but important case captures homological
    properties of the zero set of a continuous map f from K to R^n on a compact space
    K that are invariant with respect to perturbations of f. The perturbations are
    arbitrary continuous maps within L_infty distance r from f for a given r &gt;
    0. The main drawback of the approach is that the computability of well groups
    was shown only when dim K = n or n = 1. Our contribution to the theory of well
    groups is twofold: on the one hand we improve on the computability issue, but
    on the other hand we present a range of examples where the well groups are incomplete
    invariants, that is, fail to capture certain important robust properties of the
    zero set. For the first part, we identify a computable subgroup of the well group
    that is obtained by cap product with the pullback of the orientation of R^n by
    f. In other words, well groups can be algorithmically approximated from below.
    When f is smooth and dim K &lt; 2n-2, our approximation of the (dim K-n)th well
    group is exact. For the second part, we find examples of maps f, f'' from K to
    R^n with all well groups isomorphic but whose perturbations have different zero
    sets. We discuss on a possible replacement of the well groups of vector valued
    maps by an invariant of a better descriptive power and computability status. '
alternative_title:
- LIPIcs
author:
- first_name: Peter
  full_name: Franek, Peter
  id: 473294AE-F248-11E8-B48F-1D18A9856A87
  last_name: Franek
  orcid: 0000-0001-8878-8397
- first_name: Marek
  full_name: Krcál, Marek
  id: 33E21118-F248-11E8-B48F-1D18A9856A87
  last_name: Krcál
citation:
  ama: 'Franek P, Krcál M. On computability and triviality of well groups. In: Vol
    34. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2015:842-856. doi:<a href="https://doi.org/10.4230/LIPIcs.SOCG.2015.842">10.4230/LIPIcs.SOCG.2015.842</a>'
  apa: 'Franek, P., &#38; Krcál, M. (2015). On computability and triviality of well
    groups (Vol. 34, pp. 842–856). Presented at the SoCG: Symposium on Computational
    Geometry, Eindhoven, Netherlands: Schloss Dagstuhl - Leibniz-Zentrum für Informatik.
    <a href="https://doi.org/10.4230/LIPIcs.SOCG.2015.842">https://doi.org/10.4230/LIPIcs.SOCG.2015.842</a>'
  chicago: Franek, Peter, and Marek Krcál. “On Computability and Triviality of Well
    Groups,” 34:842–56. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2015. <a
    href="https://doi.org/10.4230/LIPIcs.SOCG.2015.842">https://doi.org/10.4230/LIPIcs.SOCG.2015.842</a>.
  ieee: 'P. Franek and M. Krcál, “On computability and triviality of well groups,”
    presented at the SoCG: Symposium on Computational Geometry, Eindhoven, Netherlands,
    2015, vol. 34, pp. 842–856.'
  ista: 'Franek P, Krcál M. 2015. On computability and triviality of well groups.
    SoCG: Symposium on Computational Geometry, LIPIcs, vol. 34, 842–856.'
  mla: Franek, Peter, and Marek Krcál. <i>On Computability and Triviality of Well
    Groups</i>. Vol. 34, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2015,
    pp. 842–56, doi:<a href="https://doi.org/10.4230/LIPIcs.SOCG.2015.842">10.4230/LIPIcs.SOCG.2015.842</a>.
  short: P. Franek, M. Krcál, in:, Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
    2015, pp. 842–856.
conference:
  end_date: 2015-06-25
  location: Eindhoven, Netherlands
  name: 'SoCG: Symposium on Computational Geometry'
  start_date: 2015-06-22
date_created: 2018-12-11T11:52:26Z
date_published: 2015-06-11T00:00:00Z
date_updated: 2025-09-18T14:30:52Z
day: '11'
ddc:
- '510'
department:
- _id: UlWa
- _id: HeEd
doi: 10.4230/LIPIcs.SOCG.2015.842
ec_funded: 1
file:
- access_level: open_access
  checksum: 49eb5021caafaabe5356c65b9c5f8c9c
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:13:19Z
  date_updated: 2020-07-14T12:44:59Z
  file_id: '5001'
  file_name: IST-2016-503-v1+1_32.pdf
  file_size: 623563
  relation: main_file
file_date_updated: 2020-07-14T12:44:59Z
has_accepted_license: '1'
intvolume: '        34'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 842 - 856
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '5667'
pubrep_id: '503'
quality_controlled: '1'
related_material:
  record:
  - id: '1408'
    relation: later_version
    status: public
scopus_import: 1
status: public
title: On computability and triviality of well groups
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2015'
...
---
_id: '1511'
abstract:
- lang: eng
  text: 'The fact that the complete graph K_5 does not embed in the plane has been
    generalized in two independent directions. On the one hand, the solution of the
    classical Heawood problem for graphs on surfaces established that the complete
    graph K_n embeds in a closed surface M if and only if (n-3)(n-4) is at most 6b_1(M),
    where b_1(M) is the first Z_2-Betti number of M. On the other hand, Van Kampen
    and Flores proved that the k-skeleton of the n-dimensional simplex (the higher-dimensional
    analogue of K_{n+1}) embeds in R^{2k} if and only if n is less or equal to 2k+2.
    Two decades ago, Kuhnel conjectured that the k-skeleton of the n-simplex embeds
    in a compact, (k-1)-connected 2k-manifold with kth Z_2-Betti number b_k only if
    the following generalized Heawood inequality holds: binom{n-k-1}{k+1} is at most
    binom{2k+1}{k+1} b_k. This is a common generalization of the case of graphs on
    surfaces as well as the Van Kampen--Flores theorem. In the spirit of Kuhnel''s
    conjecture, we prove that if the k-skeleton of the n-simplex embeds in a 2k-manifold
    with kth Z_2-Betti number b_k, then n is at most 2b_k binom{2k+2}{k} + 2k + 5.
    This bound is weaker than the generalized Heawood inequality, but does not require
    the assumption that M is (k-1)-connected. Our proof uses a result of Volovikov
    about maps that satisfy a certain homological triviality condition.'
acknowledgement: "The work by Z. P. was partially supported by the Charles University
  Grant SVV-2014-260103. The\r\nwork by Z. P. and M. T. was partially supported by
  the project CE-ITI (GACR P202/12/G061) of\r\nthe Czech Science Foundation and by
  the ERC Advanced Grant No. 267165. Part of the research\r\nwork of M. T. was conducted
  at IST Austria, supported by an IST Fellowship. The work by U.W.\r\nwas partially
  supported by the Swiss National Science Foundation (grants SNSF-200020-138230 and\r\nSNSF-PP00P2-138948)."
alternative_title:
- LIPIcs
author:
- first_name: Xavier
  full_name: Goaoc, Xavier
  last_name: Goaoc
- first_name: Isaac
  full_name: Mabillard, Isaac
  id: 32BF9DAA-F248-11E8-B48F-1D18A9856A87
  last_name: Mabillard
- first_name: Pavel
  full_name: Paták, Pavel
  last_name: Paták
- first_name: Zuzana
  full_name: Patakova, Zuzana
  id: 48B57058-F248-11E8-B48F-1D18A9856A87
  last_name: Patakova
  orcid: 0000-0002-3975-1683
- first_name: Martin
  full_name: Tancer, Martin
  id: 38AC689C-F248-11E8-B48F-1D18A9856A87
  last_name: Tancer
  orcid: 0000-0002-1191-6714
- first_name: Uli
  full_name: Wagner, Uli
  id: 36690CA2-F248-11E8-B48F-1D18A9856A87
  last_name: Wagner
  orcid: 0000-0002-1494-0568
citation:
  ama: 'Goaoc X, Mabillard I, Paták P, Patakova Z, Tancer M, Wagner U. On generalized
    Heawood inequalities for manifolds: A Van Kampen–Flores-type nonembeddability
    result. In: Vol 34. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2015:476-490.
    doi:<a href="https://doi.org/10.4230/LIPIcs.SOCG.2015.476">10.4230/LIPIcs.SOCG.2015.476</a>'
  apa: 'Goaoc, X., Mabillard, I., Paták, P., Patakova, Z., Tancer, M., &#38; Wagner,
    U. (2015). On generalized Heawood inequalities for manifolds: A Van Kampen–Flores-type
    nonembeddability result (Vol. 34, pp. 476–490). Presented at the SoCG: Symposium
    on Computational Geometry, Eindhoven, Netherlands: Schloss Dagstuhl - Leibniz-Zentrum
    für Informatik. <a href="https://doi.org/10.4230/LIPIcs.SOCG.2015.476">https://doi.org/10.4230/LIPIcs.SOCG.2015.476</a>'
  chicago: 'Goaoc, Xavier, Isaac Mabillard, Pavel Paták, Zuzana Patakova, Martin Tancer,
    and Uli Wagner. “On Generalized Heawood Inequalities for Manifolds: A Van Kampen–Flores-Type
    Nonembeddability Result,” 34:476–90. Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
    2015. <a href="https://doi.org/10.4230/LIPIcs.SOCG.2015.476">https://doi.org/10.4230/LIPIcs.SOCG.2015.476</a>.'
  ieee: 'X. Goaoc, I. Mabillard, P. Paták, Z. Patakova, M. Tancer, and U. Wagner,
    “On generalized Heawood inequalities for manifolds: A Van Kampen–Flores-type nonembeddability
    result,” presented at the SoCG: Symposium on Computational Geometry, Eindhoven,
    Netherlands, 2015, vol. 34, pp. 476–490.'
  ista: 'Goaoc X, Mabillard I, Paták P, Patakova Z, Tancer M, Wagner U. 2015. On generalized
    Heawood inequalities for manifolds: A Van Kampen–Flores-type nonembeddability
    result. SoCG: Symposium on Computational Geometry, LIPIcs, vol. 34, 476–490.'
  mla: 'Goaoc, Xavier, et al. <i>On Generalized Heawood Inequalities for Manifolds:
    A Van Kampen–Flores-Type Nonembeddability Result</i>. Vol. 34, Schloss Dagstuhl
    - Leibniz-Zentrum für Informatik, 2015, pp. 476–90, doi:<a href="https://doi.org/10.4230/LIPIcs.SOCG.2015.476">10.4230/LIPIcs.SOCG.2015.476</a>.'
  short: X. Goaoc, I. Mabillard, P. Paták, Z. Patakova, M. Tancer, U. Wagner, in:,
    Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2015, pp. 476–490.
conference:
  end_date: 2015-06-25
  location: Eindhoven, Netherlands
  name: 'SoCG: Symposium on Computational Geometry'
  start_date: 2015-06-22
date_created: 2018-12-11T11:52:27Z
date_published: 2015-06-11T00:00:00Z
date_updated: 2025-09-11T07:35:35Z
day: '11'
ddc:
- '510'
department:
- _id: UlWa
doi: 10.4230/LIPIcs.SOCG.2015.476
ec_funded: 1
file:
- access_level: open_access
  checksum: 0945811875351796324189312ca29e9e
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:11:18Z
  date_updated: 2020-07-14T12:44:59Z
  file_id: '4871'
  file_name: IST-2016-502-v1+1_42.pdf
  file_size: 636735
  relation: main_file
file_date_updated: 2020-07-14T12:44:59Z
has_accepted_license: '1'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 476 - 490
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '5666'
pubrep_id: '502'
quality_controlled: '1'
related_material:
  record:
  - id: '610'
    relation: later_version
    status: public
scopus_import: 1
status: public
title: 'On generalized Heawood inequalities for manifolds: A Van Kampen–Flores-type
  nonembeddability result'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: '34 '
year: '2015'
...
---
_id: '1512'
abstract:
- lang: eng
  text: 'We show that very weak topological assumptions are enough to ensure the existence
    of a Helly-type theorem. More precisely, we show that for any non-negative integers
    b and d there exists an integer h(b,d) such that the following holds. If F is
    a finite family of subsets of R^d such that the ith reduced Betti number (with
    Z_2 coefficients in singular homology) of the intersection of any proper subfamily
    G of F is at most b for every non-negative integer i less or equal to (d-1)/2,
    then F has Helly number at most h(b,d). These topological conditions are sharp:
    not controlling any of these first Betti numbers allow for families with unbounded
    Helly number. Our proofs combine homological non-embeddability results with a
    Ramsey-based approach to build, given an arbitrary simplicial complex K, some
    well-behaved chain map from C_*(K) to C_*(R^d). Both techniques are of independent
    interest.'
acknowledgement: "PP, ZP and MT were partially supported by the Charles University
  Grant GAUK 421511. ZP was\r\npartially supported by the Charles University Grant
  SVV-2014-260103. ZP and MT were partially\r\nsupported by the ERC Advanced Grant
  No. 267165 and by the project CE-ITI (GACR P202/12/G061)\r\nof the Czech Science
  Foundation. UW was partially supported by the Swiss National Science Foundation\r\n(grants
  SNSF-200020-138230 and SNSF-PP00P2-138948). Part of this work was done when XG was
  affiliated with INRIA Nancy Grand-Est and when MT was affiliated with Institutionen
  för matematik, Kungliga Tekniska Högskolan, then IST Austria."
alternative_title:
- LIPIcs
article_processing_charge: No
author:
- first_name: Xavier
  full_name: Goaoc, Xavier
  last_name: Goaoc
- first_name: Pavel
  full_name: Paták, Pavel
  last_name: Paták
- first_name: Zuzana
  full_name: Patakova, Zuzana
  last_name: Patakova
  orcid: 0000-0002-3975-1683
- first_name: Martin
  full_name: Tancer, Martin
  last_name: Tancer
  orcid: 0000-0002-1191-6714
- first_name: Uli
  full_name: Wagner, Uli
  id: 36690CA2-F248-11E8-B48F-1D18A9856A87
  last_name: Wagner
  orcid: 0000-0002-1494-0568
citation:
  ama: 'Goaoc X, Paták P, Patakova Z, Tancer M, Wagner U. Bounding Helly numbers via
    Betti numbers. In: Vol 34. Schloss Dagstuhl - Leibniz-Zentrum für Informatik;
    2015:507-521. doi:<a href="https://doi.org/10.4230/LIPIcs.SOCG.2015.507">10.4230/LIPIcs.SOCG.2015.507</a>'
  apa: 'Goaoc, X., Paták, P., Patakova, Z., Tancer, M., &#38; Wagner, U. (2015). Bounding
    Helly numbers via Betti numbers (Vol. 34, pp. 507–521). Presented at the SoCG:
    Symposium on Computational Geometry, Eindhoven, Netherlands: Schloss Dagstuhl
    - Leibniz-Zentrum für Informatik. <a href="https://doi.org/10.4230/LIPIcs.SOCG.2015.507">https://doi.org/10.4230/LIPIcs.SOCG.2015.507</a>'
  chicago: Goaoc, Xavier, Pavel Paták, Zuzana Patakova, Martin Tancer, and Uli Wagner.
    “Bounding Helly Numbers via Betti Numbers,” 34:507–21. Schloss Dagstuhl - Leibniz-Zentrum
    für Informatik, 2015. <a href="https://doi.org/10.4230/LIPIcs.SOCG.2015.507">https://doi.org/10.4230/LIPIcs.SOCG.2015.507</a>.
  ieee: 'X. Goaoc, P. Paták, Z. Patakova, M. Tancer, and U. Wagner, “Bounding Helly
    numbers via Betti numbers,” presented at the SoCG: Symposium on Computational
    Geometry, Eindhoven, Netherlands, 2015, vol. 34, pp. 507–521.'
  ista: 'Goaoc X, Paták P, Patakova Z, Tancer M, Wagner U. 2015. Bounding Helly numbers
    via Betti numbers. SoCG: Symposium on Computational Geometry, LIPIcs, vol. 34,
    507–521.'
  mla: Goaoc, Xavier, et al. <i>Bounding Helly Numbers via Betti Numbers</i>. Vol.
    34, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2015, pp. 507–21, doi:<a
    href="https://doi.org/10.4230/LIPIcs.SOCG.2015.507">10.4230/LIPIcs.SOCG.2015.507</a>.
  short: X. Goaoc, P. Paták, Z. Patakova, M. Tancer, U. Wagner, in:, Schloss Dagstuhl
    - Leibniz-Zentrum für Informatik, 2015, pp. 507–521.
conference:
  end_date: 2015-06-25
  location: Eindhoven, Netherlands
  name: 'SoCG: Symposium on Computational Geometry'
  start_date: 2015-06-22
date_created: 2018-12-11T11:52:27Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2025-06-04T08:47:27Z
day: '01'
ddc:
- '510'
department:
- _id: UlWa
doi: 10.4230/LIPIcs.SOCG.2015.507
file:
- access_level: open_access
  checksum: e6881df44d87fe0c2529c9f7b2724614
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:10:09Z
  date_updated: 2020-07-14T12:45:00Z
  file_id: '4794'
  file_name: IST-2016-501-v1+1_46.pdf
  file_size: 633712
  relation: main_file
file_date_updated: 2020-07-14T12:45:00Z
has_accepted_license: '1'
intvolume: '        34'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Submitted Version
page: 507 - 521
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '5665'
pubrep_id: '501'
quality_controlled: '1'
related_material:
  record:
  - id: '424'
    relation: later_version
    status: public
scopus_import: '1'
status: public
title: Bounding Helly numbers via Betti numbers
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2015'
...
---
_id: '1513'
abstract:
- lang: eng
  text: "Insects of the order Hemiptera (true bugs) use a wide range of mechanisms
    of sex determination, including genetic sex determination, paternal genome elimination,
    and haplodiploidy. Genetic sex determination, the prevalent mode, is generally
    controlled by a pair of XY sex chromosomes or by an XX/X0 system, but different
    configurations that include additional sex chromosomes are also present. Although
    this diversity of sex determining systems has been extensively studied at the
    cytogenetic level, only the X chromosome of the model pea aphid Acyrthosiphon
    pisum has been analyzed at the genomic level, and little is known about X chromosome
    biology in the rest of the order.\r\n\r\nIn this study, we take advantage of published
    DNA- and RNA-seq data from three additional Hemiptera species to perform a comparative
    analysis of the gene content and expression of the X chromosome throughout this
    clade. We find that, despite showing evidence of dosage compensation, the X chromosomes
    of these species show female-biased expression, and a deficit of male-biased genes,
    in direct contrast to the pea aphid X. We further detect an excess of shared gene
    content between these very distant species, suggesting that despite the diversity
    of sex determining systems, the same chromosomal element is used as the X throughout
    a large portion of the order. "
article_processing_charge: No
author:
- first_name: Arka
  full_name: Pal, Arka
  id: 6AAB2240-CA9A-11E9-9C1A-D9D1E5697425
  last_name: Pal
  orcid: 0000-0002-4530-8469
- first_name: Beatriz
  full_name: Vicoso, Beatriz
  id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
  last_name: Vicoso
  orcid: 0000-0002-4579-8306
citation:
  ama: 'Pal A, Vicoso B. The X chromosome of hemipteran insects: Conservation, dosage
    compensation and sex-biased expression. <i>Genome Biology and Evolution</i>. 2015;7(12):3259-3268.
    doi:<a href="https://doi.org/10.1093/gbe/evv215">10.1093/gbe/evv215</a>'
  apa: 'Pal, A., &#38; Vicoso, B. (2015). The X chromosome of hemipteran insects:
    Conservation, dosage compensation and sex-biased expression. <i>Genome Biology
    and Evolution</i>. Oxford University Press. <a href="https://doi.org/10.1093/gbe/evv215">https://doi.org/10.1093/gbe/evv215</a>'
  chicago: 'Pal, Arka, and Beatriz Vicoso. “The X Chromosome of Hemipteran Insects:
    Conservation, Dosage Compensation and Sex-Biased Expression.” <i>Genome Biology
    and Evolution</i>. Oxford University Press, 2015. <a href="https://doi.org/10.1093/gbe/evv215">https://doi.org/10.1093/gbe/evv215</a>.'
  ieee: 'A. Pal and B. Vicoso, “The X chromosome of hemipteran insects: Conservation,
    dosage compensation and sex-biased expression,” <i>Genome Biology and Evolution</i>,
    vol. 7, no. 12. Oxford University Press, pp. 3259–3268, 2015.'
  ista: 'Pal A, Vicoso B. 2015. The X chromosome of hemipteran insects: Conservation,
    dosage compensation and sex-biased expression. Genome Biology and Evolution. 7(12),
    3259–3268.'
  mla: 'Pal, Arka, and Beatriz Vicoso. “The X Chromosome of Hemipteran Insects: Conservation,
    Dosage Compensation and Sex-Biased Expression.” <i>Genome Biology and Evolution</i>,
    vol. 7, no. 12, Oxford University Press, 2015, pp. 3259–68, doi:<a href="https://doi.org/10.1093/gbe/evv215">10.1093/gbe/evv215</a>.'
  short: A. Pal, B. Vicoso, Genome Biology and Evolution 7 (2015) 3259–3268.
corr_author: '1'
date_created: 2018-12-11T11:52:27Z
date_published: 2015-12-01T00:00:00Z
date_updated: 2025-09-23T14:18:15Z
day: '01'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1093/gbe/evv215
ec_funded: 1
external_id:
  isi:
  - '000366498700008'
file:
- access_level: open_access
  checksum: 2b56b8c2e2a1d4cc3c9cb8daba26dd9b
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:17:29Z
  date_updated: 2020-07-14T12:45:00Z
  file_id: '5284'
  file_name: IST-2016-496-v1+1_Genome_Biol_Evol-2015-Pal-3259-68.pdf
  file_size: 858027
  relation: main_file
file_date_updated: 2020-07-14T12:45:00Z
has_accepted_license: '1'
intvolume: '         7'
isi: 1
issue: '12'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 3259 - 3268
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication: Genome Biology and Evolution
publication_status: published
publisher: Oxford University Press
publist_id: '5664'
pubrep_id: '496'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The X chromosome of hemipteran insects: Conservation, dosage compensation
  and sex-biased expression'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 7
year: '2015'
...
---
_id: '1514'
abstract:
- lang: eng
  text: 'Endocannabinoids (eCBs) play key roles in brain function, acting as modulatory
    signals in synaptic transmission and plasticity. They are recognized as retrograde
    messengers that mediate long-term synaptic depression (LTD), but their ability
    to induce long-term potentiation (LTP) is poorly known. We show that eCBs induce
    the long-term enhancement of transmitter release at single hippocampal synapses
    through stimulation of astrocytes when coincident with postsynaptic activity.
    This LTP requires the coordinated activity of the 3 elements of the tripartite
    synapse: 1) eCB-evoked astrocyte calcium signal that stimulates glutamate release;
    2) postsynaptic nitric oxide production; and 3) activation of protein kinase C
    and presynaptic group I metabotropic glutamate receptors, whose location at presynaptic
    sites was confirmed by immunoelectron microscopy. Hence, while eCBs act as retrograde
    signals to depress homoneuronal synapses, they serve as lateral messengers to
    induce LTP in distant heteroneuronal synapses through stimulation of astrocytes.
    Therefore, eCBs can trigger LTP through stimulation of astrocyte-neuron signaling,
    revealing novel cellular mechanisms of eCB effects on synaptic plasticity.'
acknowledgement: |-
  This work was supported by grants from Ministerio de Economia y Competitividad, Spain (MINECO; BFU2010-15832), European Union (HEALTH-F2-2007-202167), and Cajal Blue Brain to A.A. Grants from Spain (MINECO; BFU-2009-08404 and
  CSD2008-00005) to R.L. Grants from Spain (MINECO; Consolider, CSD2010-00045; Ramón y Cajal Program, RYC-2012-12014; and BFU2013-47265) to G.P. We thank Dr Atsu Aiba (Animal Resources, Center for Disease Biology and Integrative Medicine, Faculty of Medicine, University of Tokyo) for the donation of the mGluR1b rescue mice.
author:
- first_name: Marta
  full_name: Gómez-Gonzalo, Marta
  last_name: Gómez Gonzalo
- first_name: Marta
  full_name: Navarrete, Marta
  last_name: Navarrete
- first_name: Gertrudis
  full_name: Perea, Gertrudis
  last_name: Perea
- first_name: Ana
  full_name: Covelo, Ana
  last_name: Covelo
- first_name: Mario
  full_name: Martín-Fernández, Mario
  last_name: Martín Fernández
- first_name: Ryuichi
  full_name: Ryuichi Shigemoto
  id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
  last_name: Shigemoto
  orcid: 0000-0001-8761-9444
- first_name: Rafael
  full_name: Luján, Rafael
  last_name: Luján
- first_name: Alfonso
  full_name: Araque, Alfonso
  last_name: Araque
citation:
  ama: Gómez Gonzalo M, Navarrete M, Perea G, et al. Endocannabinoids induce lateral
    long term potentiation of transmitter release by stimulation of gliotransmission.
    <i>Cerebral Cortex</i>. 2015;25(10):3699-3712. doi:<a href="https://doi.org/10.1093/cercor/bhu231">10.1093/cercor/bhu231</a>
  apa: Gómez Gonzalo, M., Navarrete, M., Perea, G., Covelo, A., Martín Fernández,
    M., Shigemoto, R., … Araque, A. (2015). Endocannabinoids induce lateral long term
    potentiation of transmitter release by stimulation of gliotransmission. <i>Cerebral
    Cortex</i>. Oxford University Press. <a href="https://doi.org/10.1093/cercor/bhu231">https://doi.org/10.1093/cercor/bhu231</a>
  chicago: Gómez Gonzalo, Marta, Marta Navarrete, Gertrudis Perea, Ana Covelo, Mario
    Martín Fernández, Ryuichi Shigemoto, Rafael Luján, and Alfonso Araque. “Endocannabinoids
    Induce Lateral Long Term Potentiation of Transmitter Release by Stimulation of
    Gliotransmission.” <i>Cerebral Cortex</i>. Oxford University Press, 2015. <a href="https://doi.org/10.1093/cercor/bhu231">https://doi.org/10.1093/cercor/bhu231</a>.
  ieee: M. Gómez Gonzalo <i>et al.</i>, “Endocannabinoids induce lateral long term
    potentiation of transmitter release by stimulation of gliotransmission,” <i>Cerebral
    Cortex</i>, vol. 25, no. 10. Oxford University Press, pp. 3699–3712, 2015.
  ista: Gómez Gonzalo M, Navarrete M, Perea G, Covelo A, Martín Fernández M, Shigemoto
    R, Luján R, Araque A. 2015. Endocannabinoids induce lateral long term potentiation
    of transmitter release by stimulation of gliotransmission. Cerebral Cortex. 25(10),
    3699–3712.
  mla: Gómez Gonzalo, Marta, et al. “Endocannabinoids Induce Lateral Long Term Potentiation
    of Transmitter Release by Stimulation of Gliotransmission.” <i>Cerebral Cortex</i>,
    vol. 25, no. 10, Oxford University Press, 2015, pp. 3699–712, doi:<a href="https://doi.org/10.1093/cercor/bhu231">10.1093/cercor/bhu231</a>.
  short: M. Gómez Gonzalo, M. Navarrete, G. Perea, A. Covelo, M. Martín Fernández,
    R. Shigemoto, R. Luján, A. Araque, Cerebral Cortex 25 (2015) 3699–3712.
date_created: 2018-12-11T11:52:27Z
date_published: 2015-10-10T00:00:00Z
date_updated: 2021-01-12T06:51:18Z
day: '10'
doi: 10.1093/cercor/bhu231
extern: 1
intvolume: '        25'
issue: '10'
month: '10'
page: 3699 - 3712
publication: Cerebral Cortex
publication_status: published
publisher: Oxford University Press
publist_id: '5663'
quality_controlled: 0
status: public
title: Endocannabinoids induce lateral long term potentiation of transmitter release
  by stimulation of gliotransmission
type: journal_article
volume: 25
year: '2015'
...
---
_id: '1515'
abstract:
- lang: eng
  text: Type 1 metabotropic glutamate (mGlu1) receptors play a pivotal role in different
    forms of synaptic plasticity in the cerebellar cortex, e.g. long-term depression
    at glutamatergic synapses and rebound potentiation at GABAergic synapses. These
    various forms of plasticity might depend on the subsynaptic arrangement of the
    receptor in Purkinje cells that can be regulated by protein-protein interactions.
    This study investigated, by means of the freeze-fracture replica immunogold labelling
    method, the subcellular localization of mGlu1 receptors in the rodent cerebellum
    and whether Homer proteins regulate their subsynaptic distribution. We observed
    a widespread extrasynaptic localization of mGlu1 receptors and confirmed their
    peri-synaptic enrichment at glutamatergic synapses. Conversely, we detected mGlu1
    receptors within the main body of GABAergic synapses onto Purkinje cell dendrites.
    Although Homer proteins are known to interact with the mGlu1 receptor C-terminus,
    we could not detect Homer3, the most abundant Homer protein in the cerebellar
    cortex, at GABAergic synapses by pre-embedding and post-embedding immunoelectron
    microscopy. We then hypothesized a critical role for Homer proteins in the peri-junctional
    localization of mGlu1 receptors at glutamatergic synapses. To disrupt Homer-associated
    protein complexes, mice were tail-vein injected with the membrane-permeable dominant-negative
    TAT-Homer1a. Freeze-fracture replica immunogold labelling analysis showed no significant
    alteration in the mGlu1 receptor distribution pattern at parallel fibre-Purkinje
    cell synapses, suggesting that other scaffolding proteins are involved in the
    peri-synaptic confinement. The identification of interactors that regulate the
    subsynaptic localization of the mGlu1 receptor at neurochemically distinct synapses
    may offer new insight into its trafficking and intracellular signalling.
acknowledgement: This work was supported by the Austrian Science Fund (FWF) (project
  W012060-10 to F.F.), The Japan Society for the Promotion of Science (JSPS) (to R.S.)
  and Agence Nationale de la Recherche (ANR-11-BSV4-018-03, DELTAPLAN), Région Languedoc-Roussillon
  (Chercheur d’Avenir) (to J.P.). The authors thank S. Schönherr for excellent technical
  support and Dr Furuichi for kindly providing anti-Homer3 antibodies.
author:
- first_name: Mahnaz
  full_name: Mansouri, Mahnaz
  last_name: Mansouri
- first_name: Yu
  full_name: Kasugai, Yu
  last_name: Kasugai
- first_name: Yugo
  full_name: Fukazawa, Yugo
  last_name: Fukazawa
- first_name: Federica
  full_name: Bertaso, Federica
  last_name: Bertaso
- first_name: Fabrice
  full_name: Raynaud, Fabrice
  last_name: Raynaud
- first_name: Julie
  full_name: Perroy, Julie
  last_name: Perroy
- first_name: Laurent
  full_name: Fagni, Laurent
  last_name: Fagni
- first_name: Walter
  full_name: Walter Kaufmann
  id: 3F99E422-F248-11E8-B48F-1D18A9856A87
  last_name: Kaufmann
  orcid: 0000-0001-9735-5315
- first_name: Masahiko
  full_name: Watanabe, Masahiko
  last_name: Watanabe
- first_name: Ryuichi
  full_name: Ryuichi Shigemoto
  id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
  last_name: Shigemoto
  orcid: 0000-0001-8761-9444
- first_name: Francesco
  full_name: Ferraguti, Francesco
  last_name: Ferraguti
citation:
  ama: Mansouri M, Kasugai Y, Fukazawa Y, et al. Distinct subsynaptic localization
    of type 1 metabotropic glutamate receptors at glutamatergic and GABAergic synapses
    in the rodent cerebellar cortex. <i>European Journal of Neuroscience</i>. 2015;41(2):157-167.
    doi:<a href="https://doi.org/10.1111/ejn.12779">10.1111/ejn.12779</a>
  apa: Mansouri, M., Kasugai, Y., Fukazawa, Y., Bertaso, F., Raynaud, F., Perroy,
    J., … Ferraguti, F. (2015). Distinct subsynaptic localization of type 1 metabotropic
    glutamate receptors at glutamatergic and GABAergic synapses in the rodent cerebellar
    cortex. <i>European Journal of Neuroscience</i>. Wiley-Blackwell. <a href="https://doi.org/10.1111/ejn.12779">https://doi.org/10.1111/ejn.12779</a>
  chicago: Mansouri, Mahnaz, Yu Kasugai, Yugo Fukazawa, Federica Bertaso, Fabrice
    Raynaud, Julie Perroy, Laurent Fagni, et al. “Distinct Subsynaptic Localization
    of Type 1 Metabotropic Glutamate Receptors at Glutamatergic and GABAergic Synapses
    in the Rodent Cerebellar Cortex.” <i>European Journal of Neuroscience</i>. Wiley-Blackwell,
    2015. <a href="https://doi.org/10.1111/ejn.12779">https://doi.org/10.1111/ejn.12779</a>.
  ieee: M. Mansouri <i>et al.</i>, “Distinct subsynaptic localization of type 1 metabotropic
    glutamate receptors at glutamatergic and GABAergic synapses in the rodent cerebellar
    cortex,” <i>European Journal of Neuroscience</i>, vol. 41, no. 2. Wiley-Blackwell,
    pp. 157–167, 2015.
  ista: Mansouri M, Kasugai Y, Fukazawa Y, Bertaso F, Raynaud F, Perroy J, Fagni L,
    Kaufmann W, Watanabe M, Shigemoto R, Ferraguti F. 2015. Distinct subsynaptic localization
    of type 1 metabotropic glutamate receptors at glutamatergic and GABAergic synapses
    in the rodent cerebellar cortex. European Journal of Neuroscience. 41(2), 157–167.
  mla: Mansouri, Mahnaz, et al. “Distinct Subsynaptic Localization of Type 1 Metabotropic
    Glutamate Receptors at Glutamatergic and GABAergic Synapses in the Rodent Cerebellar
    Cortex.” <i>European Journal of Neuroscience</i>, vol. 41, no. 2, Wiley-Blackwell,
    2015, pp. 157–67, doi:<a href="https://doi.org/10.1111/ejn.12779">10.1111/ejn.12779</a>.
  short: M. Mansouri, Y. Kasugai, Y. Fukazawa, F. Bertaso, F. Raynaud, J. Perroy,
    L. Fagni, W. Kaufmann, M. Watanabe, R. Shigemoto, F. Ferraguti, European Journal
    of Neuroscience 41 (2015) 157–167.
date_created: 2018-12-11T11:52:28Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2023-02-23T10:02:24Z
day: '01'
doi: 10.1111/ejn.12779
extern: 1
intvolume: '        41'
issue: '2'
month: '01'
page: 157 - 167
publication: European Journal of Neuroscience
publication_status: published
publisher: Wiley-Blackwell
publist_id: '5662'
quality_controlled: 0
status: public
title: Distinct subsynaptic localization of type 1 metabotropic glutamate receptors
  at glutamatergic and GABAergic synapses in the rodent cerebellar cortex
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
volume: 41
year: '2015'
...
