---
_id: '12633'
abstract:
- lang: eng
text: We use two hydrological models of varying complexity to study the Juncal River
Basin in the Central Andes of Chile with the aim to understand the degree of conceptualization
and the spatial structure that are needed to model present and future streamflows.
We use a conceptual semi-distributed model based on elevation bands [Water Evaluation
and Planning (WEAP)], frequently used for water management, and a physically oriented,
fully distributed model [Topographic Kinematic Wave Approximation and Integration
ETH Zurich (TOPKAPI-ETH)] developed for research purposes mainly. We evaluate
the ability of the two models to reproduce the key hydrological processes in the
basin with emphasis on snow accumulation and melt, streamflow and the relationships
between internal processes. Both models are capable of reproducing observed runoff
and the evolution of Moderate-resolution Imaging Spectroradiometer snow cover
adequately. In spite of WEAP's simple and conceptual approach for modelling snowmelt
and its lack of glacier representation and snow gravitational redistribution as
well as a proper routing algorithm, this model can reproduce historical data with
a similar goodness of fit as the more complex TOPKAPI-ETH. We show that the performance
of both models can be improved by using measured precipitation gradients of higher
temporal resolution. In contrast to the good performance of the conceptual model
for the present climate, however, we demonstrate that the simplifications in WEAP
lead to error compensation, which results in different predictions in simulated
melt and runoff for a potentially warmer future climate. TOPKAPI-ETH, using a
more physical representation of processes, depends less on calibration and thus
is less subject to a compensation of errors through different model components.
Our results show that data obtained locally in ad hoc short-term field campaigns
are needed to complement data extrapolated from long-term records for simulating
changes in the water cycle of high-elevation catchments but that these data can
only be efficiently used by a model applying a spatially distributed physical
representation of hydrological processes.
article_processing_charge: No
article_type: original
author:
- first_name: S.
full_name: Ragettli, S.
last_name: Ragettli
- first_name: G.
full_name: Cortés, G.
last_name: Cortés
- first_name: J.
full_name: McPhee, J.
last_name: McPhee
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
citation:
ama: Ragettli S, Cortés G, McPhee J, Pellicciotti F. An evaluation of approaches
for modelling hydrological processes in high-elevation, glacierized Andean watersheds.
Hydrological Processes. 2013;28(23):5674-5695. doi:10.1002/hyp.10055
apa: Ragettli, S., Cortés, G., McPhee, J., & Pellicciotti, F. (2013). An evaluation
of approaches for modelling hydrological processes in high-elevation, glacierized
Andean watersheds. Hydrological Processes. Wiley. https://doi.org/10.1002/hyp.10055
chicago: Ragettli, S., G. Cortés, J. McPhee, and Francesca Pellicciotti. “An Evaluation
of Approaches for Modelling Hydrological Processes in High-Elevation, Glacierized
Andean Watersheds.” Hydrological Processes. Wiley, 2013. https://doi.org/10.1002/hyp.10055.
ieee: S. Ragettli, G. Cortés, J. McPhee, and F. Pellicciotti, “An evaluation of
approaches for modelling hydrological processes in high-elevation, glacierized
Andean watersheds,” Hydrological Processes, vol. 28, no. 23. Wiley, pp.
5674–5695, 2013.
ista: Ragettli S, Cortés G, McPhee J, Pellicciotti F. 2013. An evaluation of approaches
for modelling hydrological processes in high-elevation, glacierized Andean watersheds.
Hydrological Processes. 28(23), 5674–5695.
mla: Ragettli, S., et al. “An Evaluation of Approaches for Modelling Hydrological
Processes in High-Elevation, Glacierized Andean Watersheds.” Hydrological Processes,
vol. 28, no. 23, Wiley, 2013, pp. 5674–95, doi:10.1002/hyp.10055.
short: S. Ragettli, G. Cortés, J. McPhee, F. Pellicciotti, Hydrological Processes
28 (2013) 5674–5695.
date_created: 2023-02-20T08:16:39Z
date_published: 2013-09-06T00:00:00Z
date_updated: 2023-02-24T08:48:40Z
day: '06'
doi: 10.1002/hyp.10055
extern: '1'
intvolume: ' 28'
issue: '23'
keyword:
- Water Science and Technology
language:
- iso: eng
month: '09'
oa_version: None
page: 5674-5695
publication: Hydrological Processes
publication_identifier:
issn:
- 0885-6087
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: An evaluation of approaches for modelling hydrological processes in high-elevation,
glacierized Andean watersheds
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 28
year: '2013'
...
---
_id: '12638'
abstract:
- lang: eng
text: Central Asian water resources largely depend on melt water generated in the
Pamir and Tien Shan mountain ranges. To estimate future water availability in
this region, it is necessary to use climate projections to estimate the future
glacier extent and volume. In this study, we evaluate the impact of uncertainty
in climate change projections on the future glacier extent in the Amu and Syr
Darya river basins. To this end we use the latest climate change projections generated
for the upcoming IPCC report (CMIP5) and, for comparison, projections used in
the fourth IPCC assessment (CMIP3). With these projections we force a regionalized
glacier mass balance model, and estimate changes in the basins' glacier extent
as a function of the glacier size distribution in the basins and projected temperature
and precipitation. This glacier mass balance model is specifically developed for
implementation in large scale hydrological models, where the spatial resolution
does not allow for simulating individual glaciers and data scarcity is an issue.
Although the CMIP5 ensemble results in greater regional warming than the CMIP3
ensemble and the range in projections for temperature as well as precipitation
is wider for the CMIP5 than for the CMIP3, the spread in projections of future
glacier extent in Central Asia is similar for both ensembles. This is because
differences in temperature rise are small during periods of maximum melt (July–September)
while differences in precipitation change are small during the period of maximum
accumulation (October–February). However, the model uncertainty due to parameter
uncertainty is high, and has roughly the same importance as uncertainty in the
climate projections. Uncertainty about the size of the decline in glacier extent
remains large, making estimates of future Central Asian glacier evolution and
downstream water availability uncertain.
article_processing_charge: No
article_type: original
author:
- first_name: A. F.
full_name: Lutz, A. F.
last_name: Lutz
- first_name: W. W.
full_name: Immerzeel, W. W.
last_name: Immerzeel
- first_name: A.
full_name: Gobiet, A.
last_name: Gobiet
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
- first_name: M. F. P.
full_name: Bierkens, M. F. P.
last_name: Bierkens
citation:
ama: Lutz AF, Immerzeel WW, Gobiet A, Pellicciotti F, Bierkens MFP. Comparison of
climate change signals in CMIP3 and CMIP5 multi-model ensembles and implications
for Central Asian glaciers. Hydrology and Earth System Sciences. 2013;17(9):3661-3677.
doi:10.5194/hess-17-3661-2013
apa: Lutz, A. F., Immerzeel, W. W., Gobiet, A., Pellicciotti, F., & Bierkens,
M. F. P. (2013). Comparison of climate change signals in CMIP3 and CMIP5 multi-model
ensembles and implications for Central Asian glaciers. Hydrology and Earth
System Sciences. Copernicus GmbH. https://doi.org/10.5194/hess-17-3661-2013
chicago: Lutz, A. F., W. W. Immerzeel, A. Gobiet, Francesca Pellicciotti, and M.
F. P. Bierkens. “Comparison of Climate Change Signals in CMIP3 and CMIP5 Multi-Model
Ensembles and Implications for Central Asian Glaciers.” Hydrology and Earth
System Sciences. Copernicus GmbH, 2013. https://doi.org/10.5194/hess-17-3661-2013.
ieee: A. F. Lutz, W. W. Immerzeel, A. Gobiet, F. Pellicciotti, and M. F. P. Bierkens,
“Comparison of climate change signals in CMIP3 and CMIP5 multi-model ensembles
and implications for Central Asian glaciers,” Hydrology and Earth System Sciences,
vol. 17, no. 9. Copernicus GmbH, pp. 3661–3677, 2013.
ista: Lutz AF, Immerzeel WW, Gobiet A, Pellicciotti F, Bierkens MFP. 2013. Comparison
of climate change signals in CMIP3 and CMIP5 multi-model ensembles and implications
for Central Asian glaciers. Hydrology and Earth System Sciences. 17(9), 3661–3677.
mla: Lutz, A. F., et al. “Comparison of Climate Change Signals in CMIP3 and CMIP5
Multi-Model Ensembles and Implications for Central Asian Glaciers.” Hydrology
and Earth System Sciences, vol. 17, no. 9, Copernicus GmbH, 2013, pp. 3661–77,
doi:10.5194/hess-17-3661-2013.
short: A.F. Lutz, W.W. Immerzeel, A. Gobiet, F. Pellicciotti, M.F.P. Bierkens, Hydrology
and Earth System Sciences 17 (2013) 3661–3677.
date_created: 2023-02-20T08:17:05Z
date_published: 2013-09-01T00:00:00Z
date_updated: 2023-02-24T08:19:48Z
day: '01'
doi: 10.5194/hess-17-3661-2013
extern: '1'
intvolume: ' 17'
issue: '9'
keyword:
- General Earth and Planetary Sciences
- General Engineering
- General Environmental Science
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.5194/hess-17-3661-2013
month: '09'
oa: 1
oa_version: Published Version
page: 3661-3677
publication: Hydrology and Earth System Sciences
publication_identifier:
issn:
- 1607-7938
publication_status: published
publisher: Copernicus GmbH
quality_controlled: '1'
scopus_import: '1'
status: public
title: Comparison of climate change signals in CMIP3 and CMIP5 multi-model ensembles
and implications for Central Asian glaciers
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2013'
...
---
_id: '12639'
abstract:
- lang: eng
text: 'In the headwater catchments of the main Asian rivers, glaciohydrological
models are a useful tool to anticipate impacts of climatic changes. However, the
reliability of their projections strongly depends on the quality and quantity
of data that are available for parameter estimation, model calibration and validation,
as well as on the accuracy of climate change projections. In this study the physically
oriented, glaciohydrological model TOPKAPI-ETH is used to simulate future changes
in snow, glacier, and runoff from the Hunza River Basin in northern Pakistan.
Three key sources of model uncertainty in future runoff projections are compared:
model parameters, climate projections, and natural climate variability. A novel
approach, applicable also to ungauged catchments, is used to determine which model
parameters and model components significantly affect the overall model uncertainty.
We show that the model is capable of reproducing streamflow and glacier mass balances,
but that all analyzed sources of uncertainty significantly affect the reliability
of future projections, and that their effect is variable in time and in space.
The effect of parametric uncertainty often exceeds the impact of climate uncertainty
and natural climate variability, especially in heavily glacierized subcatchments.
The results of the uncertainty analysis allow detailed recommendations on network
design and the timing and location of field measurements, which could efficiently
help to reduce model uncertainty in the future.'
article_processing_charge: No
article_type: original
author:
- first_name: S.
full_name: Ragettli, S.
last_name: Ragettli
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
- first_name: R.
full_name: Bordoy, R.
last_name: Bordoy
- first_name: W. W.
full_name: Immerzeel, W. W.
last_name: Immerzeel
citation:
ama: Ragettli S, Pellicciotti F, Bordoy R, Immerzeel WW. Sources of uncertainty
in modeling the glaciohydrological response of a Karakoram watershed to climate
change. Water Resources Research. 2013;49(9):6048-6066. doi:10.1002/wrcr.20450
apa: Ragettli, S., Pellicciotti, F., Bordoy, R., & Immerzeel, W. W. (2013).
Sources of uncertainty in modeling the glaciohydrological response of a Karakoram
watershed to climate change. Water Resources Research. American Geophysical
Union. https://doi.org/10.1002/wrcr.20450
chicago: Ragettli, S., Francesca Pellicciotti, R. Bordoy, and W. W. Immerzeel. “Sources
of Uncertainty in Modeling the Glaciohydrological Response of a Karakoram Watershed
to Climate Change.” Water Resources Research. American Geophysical Union,
2013. https://doi.org/10.1002/wrcr.20450.
ieee: S. Ragettli, F. Pellicciotti, R. Bordoy, and W. W. Immerzeel, “Sources of
uncertainty in modeling the glaciohydrological response of a Karakoram watershed
to climate change,” Water Resources Research, vol. 49, no. 9. American
Geophysical Union, pp. 6048–6066, 2013.
ista: Ragettli S, Pellicciotti F, Bordoy R, Immerzeel WW. 2013. Sources of uncertainty
in modeling the glaciohydrological response of a Karakoram watershed to climate
change. Water Resources Research. 49(9), 6048–6066.
mla: Ragettli, S., et al. “Sources of Uncertainty in Modeling the Glaciohydrological
Response of a Karakoram Watershed to Climate Change.” Water Resources Research,
vol. 49, no. 9, American Geophysical Union, 2013, pp. 6048–66, doi:10.1002/wrcr.20450.
short: S. Ragettli, F. Pellicciotti, R. Bordoy, W.W. Immerzeel, Water Resources
Research 49 (2013) 6048–6066.
date_created: 2023-02-20T08:17:12Z
date_published: 2013-03-01T00:00:00Z
date_updated: 2023-02-24T08:16:19Z
day: '01'
doi: 10.1002/wrcr.20450
extern: '1'
intvolume: ' 49'
issue: '9'
keyword:
- Water Science and Technology
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1002/wrcr.20450
month: '03'
oa: 1
oa_version: Published Version
page: 6048-6066
publication: Water Resources Research
publication_identifier:
issn:
- 0043-1397
publication_status: published
publisher: American Geophysical Union
quality_controlled: '1'
scopus_import: '1'
status: public
title: Sources of uncertainty in modeling the glaciohydrological response of a Karakoram
watershed to climate change
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 49
year: '2013'
...
---
_id: '12640'
abstract:
- lang: eng
text: Greater Himalayan glaciers are retreating and losing mass at rates comparable
to glaciers in other regions of the world1,2,3,4,5. Assessments of future changes
and their associated hydrological impacts are scarce, oversimplify glacier dynamics
or include a limited number of climate models6,7,8,9. Here, we use results from
the latest ensemble of climate models in combination with a high-resolution glacio-hydrological
model to assess the hydrological impact of climate change on two climatically
contrasting watersheds in the Greater Himalaya, the Baltoro and Langtang watersheds
that drain into the Indus and Ganges rivers, respectively. We show that the largest
uncertainty in future runoff is a result of variations in projected precipitation
between climate models. In both watersheds, strong, but highly variable, increases
in future runoff are projected and, despite the different characteristics of the
watersheds, their responses are surprisingly similar. In both cases, glaciers
will recede but net glacier melt runoff is on a rising limb at least until 2050.
In combination with a positive change in precipitation, water availability during
this century is not likely to decline. We conclude that river basins that depend
on monsoon rains and glacier melt will continue to sustain the increasing water
demands expected in these areas10.
article_processing_charge: No
article_type: letter_note
author:
- first_name: W. W.
full_name: Immerzeel, W. W.
last_name: Immerzeel
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
- first_name: M. F. P.
full_name: Bierkens, M. F. P.
last_name: Bierkens
citation:
ama: Immerzeel WW, Pellicciotti F, Bierkens MFP. Rising river flows throughout the
twenty-first century in two Himalayan glacierized watersheds. Nature Geoscience.
2013;6(9):742-745. doi:10.1038/ngeo1896
apa: Immerzeel, W. W., Pellicciotti, F., & Bierkens, M. F. P. (2013). Rising
river flows throughout the twenty-first century in two Himalayan glacierized watersheds.
Nature Geoscience. Springer Nature. https://doi.org/10.1038/ngeo1896
chicago: Immerzeel, W. W., Francesca Pellicciotti, and M. F. P. Bierkens. “Rising
River Flows throughout the Twenty-First Century in Two Himalayan Glacierized Watersheds.”
Nature Geoscience. Springer Nature, 2013. https://doi.org/10.1038/ngeo1896.
ieee: W. W. Immerzeel, F. Pellicciotti, and M. F. P. Bierkens, “Rising river flows
throughout the twenty-first century in two Himalayan glacierized watersheds,”
Nature Geoscience, vol. 6, no. 9. Springer Nature, pp. 742–745, 2013.
ista: Immerzeel WW, Pellicciotti F, Bierkens MFP. 2013. Rising river flows throughout
the twenty-first century in two Himalayan glacierized watersheds. Nature Geoscience.
6(9), 742–745.
mla: Immerzeel, W. W., et al. “Rising River Flows throughout the Twenty-First Century
in Two Himalayan Glacierized Watersheds.” Nature Geoscience, vol. 6, no.
9, Springer Nature, 2013, pp. 742–45, doi:10.1038/ngeo1896.
short: W.W. Immerzeel, F. Pellicciotti, M.F.P. Bierkens, Nature Geoscience 6 (2013)
742–745.
date_created: 2023-02-20T08:17:17Z
date_published: 2013-09-13T00:00:00Z
date_updated: 2023-02-21T10:46:37Z
day: '13'
doi: 10.1038/ngeo1896
extern: '1'
intvolume: ' 6'
issue: '9'
keyword:
- General Earth and Planetary Sciences
language:
- iso: eng
month: '09'
oa_version: None
page: 742-745
publication: Nature Geoscience
publication_identifier:
eissn:
- 1752-0908
issn:
- 1752-0894
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Rising river flows throughout the twenty-first century in two Himalayan glacierized
watersheds
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2013'
...
---
_id: '12641'
abstract:
- lang: eng
text: We investigate the sensitivity of a distributed enhanced temperature-index
(ETI) melt model, in order to understand which parameters have the largest influence
on model outputs and thus need to be accurately known. We use melt and meteorological
data from two Alpine glaciers and one glacier in the Andes of Chile. Sensitivity
analysis is conducted in a systematic way in terms of parameters and the different
conditions (day, night, clear-sky, overcast), melt seasons and glaciers examined.
The sensitivity of total melt to changes in individual parameters is calculated
using a local method around the optimal value of the parameters. We verify that
the parameters are optimal at the distributed scale and assess the model uncertainty
induced by uncertainty in the parameters using a Monte Carlo technique. Model
sensitivity to parameters is consistent across melt seasons, glaciers, different
conditions and the daily statistics examined. The parameters to which the model
is most sensitive are the shortwave-radiation factor, the temperature lapse rate
for extrapolation of air temperature, the albedo parameters, the temperature threshold
and the cloud transmittance factor parameters. A parameter uncertainty of 5% results
in a model uncertainty of 5.6% of mean melt on Haut Glacier d’Arolla, Switzerland.
article_processing_charge: No
article_type: original
author:
- first_name: Martin
full_name: Heynen, Martin
last_name: Heynen
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
- first_name: Marco
full_name: Carenzo, Marco
last_name: Carenzo
citation:
ama: Heynen M, Pellicciotti F, Carenzo M. Parameter sensitivity of a distributed
enhanced temperature-index melt model. Annals of Glaciology. 2013;54(63):311-321.
doi:10.3189/2013aog63a537
apa: Heynen, M., Pellicciotti, F., & Carenzo, M. (2013). Parameter sensitivity
of a distributed enhanced temperature-index melt model. Annals of Glaciology.
International Glaciological Society. https://doi.org/10.3189/2013aog63a537
chicago: Heynen, Martin, Francesca Pellicciotti, and Marco Carenzo. “Parameter Sensitivity
of a Distributed Enhanced Temperature-Index Melt Model.” Annals of Glaciology.
International Glaciological Society, 2013. https://doi.org/10.3189/2013aog63a537.
ieee: M. Heynen, F. Pellicciotti, and M. Carenzo, “Parameter sensitivity of a distributed
enhanced temperature-index melt model,” Annals of Glaciology, vol. 54,
no. 63. International Glaciological Society, pp. 311–321, 2013.
ista: Heynen M, Pellicciotti F, Carenzo M. 2013. Parameter sensitivity of a distributed
enhanced temperature-index melt model. Annals of Glaciology. 54(63), 311–321.
mla: Heynen, Martin, et al. “Parameter Sensitivity of a Distributed Enhanced Temperature-Index
Melt Model.” Annals of Glaciology, vol. 54, no. 63, International Glaciological
Society, 2013, pp. 311–21, doi:10.3189/2013aog63a537.
short: M. Heynen, F. Pellicciotti, M. Carenzo, Annals of Glaciology 54 (2013) 311–321.
date_created: 2023-02-20T08:17:21Z
date_published: 2013-08-01T00:00:00Z
date_updated: 2023-02-21T10:43:42Z
day: '01'
doi: 10.3189/2013aog63a537
extern: '1'
intvolume: ' 54'
issue: '63'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.3189/2013aog63a537
month: '08'
oa: 1
oa_version: Published Version
page: 311-321
publication: Annals of Glaciology
publication_identifier:
eissn:
- 1727-5644
issn:
- 0260-3055
publication_status: published
publisher: International Glaciological Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Parameter sensitivity of a distributed enhanced temperature-index melt model
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 54
year: '2013'
...
---
_id: '12642'
abstract:
- lang: eng
text: Near-surface air temperature, typically measured at a height of 2 m, is the
most important control on the energy exchange and the melt rate at a snow or ice
surface. It is distributed in a simplistic manner in most glacier melt models
by using constant linear lapse rates, which poorly represent the actual spatial
and temporal variability of air temperature. In this paper, we test a simple thermodynamic
model proposed by Greuell and Böhm in 1998 as an alternative, using a new dataset
of air temperature measurements from along the flowline of Haut Glacier d’Arolla,
Switzerland. The unmodified model performs little better than assuming a constant
linear lapse rate. When modified to allow the ratio of the boundary layer height
to the bulk heat transfer coefficient to vary along the flowline, the model matches
measured air temperatures better, and a further reduction of the root-mean-square
error is obtained, although there is still considerable scope for improvement.
The modified model is shown to perform best under conditions favourable to the
development of katabatic winds – few clouds, positive ambient air temperature,
limited influence of synoptic or valley winds and a long fetch – but its performance
is poor under cloudy conditions.
article_processing_charge: No
article_type: original
author:
- first_name: Lene
full_name: Petersen, Lene
last_name: Petersen
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
- first_name: Inge
full_name: Juszak, Inge
last_name: Juszak
- first_name: Marco
full_name: Carenzo, Marco
last_name: Carenzo
- first_name: Ben
full_name: Brock, Ben
last_name: Brock
citation:
ama: 'Petersen L, Pellicciotti F, Juszak I, Carenzo M, Brock B. Suitability of a
constant air temperature lapse rate over an Alpine glacier: Testing the Greuell
and Böhm model as an alternative. Annals of Glaciology. 2013;54(63):120-130.
doi:10.3189/2013aog63a477'
apa: 'Petersen, L., Pellicciotti, F., Juszak, I., Carenzo, M., & Brock, B. (2013).
Suitability of a constant air temperature lapse rate over an Alpine glacier: Testing
the Greuell and Böhm model as an alternative. Annals of Glaciology. International
Glaciological Society. https://doi.org/10.3189/2013aog63a477'
chicago: 'Petersen, Lene, Francesca Pellicciotti, Inge Juszak, Marco Carenzo, and
Ben Brock. “Suitability of a Constant Air Temperature Lapse Rate over an Alpine
Glacier: Testing the Greuell and Böhm Model as an Alternative.” Annals of Glaciology.
International Glaciological Society, 2013. https://doi.org/10.3189/2013aog63a477.'
ieee: 'L. Petersen, F. Pellicciotti, I. Juszak, M. Carenzo, and B. Brock, “Suitability
of a constant air temperature lapse rate over an Alpine glacier: Testing the Greuell
and Böhm model as an alternative,” Annals of Glaciology, vol. 54, no. 63.
International Glaciological Society, pp. 120–130, 2013.'
ista: 'Petersen L, Pellicciotti F, Juszak I, Carenzo M, Brock B. 2013. Suitability
of a constant air temperature lapse rate over an Alpine glacier: Testing the Greuell
and Böhm model as an alternative. Annals of Glaciology. 54(63), 120–130.'
mla: 'Petersen, Lene, et al. “Suitability of a Constant Air Temperature Lapse Rate
over an Alpine Glacier: Testing the Greuell and Böhm Model as an Alternative.”
Annals of Glaciology, vol. 54, no. 63, International Glaciological Society,
2013, pp. 120–30, doi:10.3189/2013aog63a477.'
short: L. Petersen, F. Pellicciotti, I. Juszak, M. Carenzo, B. Brock, Annals of
Glaciology 54 (2013) 120–130.
date_created: 2023-02-20T08:17:29Z
date_published: 2013-08-01T00:00:00Z
date_updated: 2023-02-21T10:18:24Z
day: '01'
doi: 10.3189/2013aog63a477
extern: '1'
intvolume: ' 54'
issue: '63'
keyword:
- Earth-Surface Processes
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.3189/2013aog63a477
month: '08'
oa: 1
oa_version: Published Version
page: 120-130
publication: Annals of Glaciology
publication_identifier:
eissn:
- 1727-5644
issn:
- 0260-3055
publication_status: published
publisher: International Glaciological Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Suitability of a constant air temperature lapse rate over an Alpine glacier:
Testing the Greuell and Böhm model as an alternative'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 54
year: '2013'
...
---
_id: '12643'
abstract:
- lang: eng
text: Parameterizations of incoming longwave radiation are increasingly receiving
attention for both low and high elevation glacierized sites. In this paper, we
test 13 clear-sky parameterizations combined with seven cloud corrections for
all-sky atmospheric emissivity at one location on Haut Glacier d'Arolla. We also
analyze the four seasons separately and conduct a cross-validation to test the
parameters’ robustness. The best parameterization is the one by Dilley and O'Brien,
B for clear-sky conditions combined with Unsworth and Monteith cloud correction.
This model is also the most robust when tested in cross-validation. When validated
at different sites in the southern Alps of Switzerland and north-western Italian
Alps, all parameterizations show a substantial decrease in performance, except
for one site, thus suggesting that it is important to recalibrate parameterizations
of incoming longwave radiation for different locations. We argue that this is
due to differences in the structure of the atmosphere at the sites. We also quantify
the effect that the incoming longwave radiation parameterizations have on energy-balance
melt modeling, and show that recalibration of model parameters is needed. Using
parameters from other sites leads to a significant underestimation of melt and
to an error that is larger than that associated with using different parameterizations.
Once recalibrated, however, the parameters of most models seem to be stable over
seasons and years at the location on Haut Glacier d'Arolla.
article_processing_charge: No
article_type: original
author:
- first_name: I.
full_name: Juszak, I.
last_name: Juszak
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
citation:
ama: 'Juszak I, Pellicciotti F. A comparison of parameterizations of incoming longwave
radiation over melting glaciers: Model robustness and seasonal variability. Journal
of Geophysical Research: Atmospheres. 2013;118(8):3066-3084. doi:10.1002/jgrd.50277'
apa: 'Juszak, I., & Pellicciotti, F. (2013). A comparison of parameterizations
of incoming longwave radiation over melting glaciers: Model robustness and seasonal
variability. Journal of Geophysical Research: Atmospheres. American Geophysical
Union. https://doi.org/10.1002/jgrd.50277'
chicago: 'Juszak, I., and Francesca Pellicciotti. “A Comparison of Parameterizations
of Incoming Longwave Radiation over Melting Glaciers: Model Robustness and Seasonal
Variability.” Journal of Geophysical Research: Atmospheres. American Geophysical
Union, 2013. https://doi.org/10.1002/jgrd.50277.'
ieee: 'I. Juszak and F. Pellicciotti, “A comparison of parameterizations of incoming
longwave radiation over melting glaciers: Model robustness and seasonal variability,”
Journal of Geophysical Research: Atmospheres, vol. 118, no. 8. American
Geophysical Union, pp. 3066–3084, 2013.'
ista: 'Juszak I, Pellicciotti F. 2013. A comparison of parameterizations of incoming
longwave radiation over melting glaciers: Model robustness and seasonal variability.
Journal of Geophysical Research: Atmospheres. 118(8), 3066–3084.'
mla: 'Juszak, I., and Francesca Pellicciotti. “A Comparison of Parameterizations
of Incoming Longwave Radiation over Melting Glaciers: Model Robustness and Seasonal
Variability.” Journal of Geophysical Research: Atmospheres, vol. 118, no.
8, American Geophysical Union, 2013, pp. 3066–84, doi:10.1002/jgrd.50277.'
short: 'I. Juszak, F. Pellicciotti, Journal of Geophysical Research: Atmospheres
118 (2013) 3066–3084.'
date_created: 2023-02-20T08:17:34Z
date_published: 2013-04-27T00:00:00Z
date_updated: 2023-02-21T10:10:46Z
day: '27'
doi: 10.1002/jgrd.50277
extern: '1'
intvolume: ' 118'
issue: '8'
keyword:
- Space and Planetary Science
- Earth and Planetary Sciences (miscellaneous)
- Atmospheric Science
- Geophysics
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1002/jgrd.50277
month: '04'
oa: 1
oa_version: Published Version
page: 3066-3084
publication: 'Journal of Geophysical Research: Atmospheres'
publication_identifier:
issn:
- 2169-897X
publication_status: published
publisher: American Geophysical Union
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'A comparison of parameterizations of incoming longwave radiation over melting
glaciers: Model robustness and seasonal variability'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 118
year: '2013'
...
---
_id: '1304'
abstract:
- lang: eng
text: When confronted with a large-field stimulus rotating around the vertical body
axis, flies display a following behavior called "optomotor response."
As neural control elements, the large tangential horizontal system (HS) cells
of the lobula plate have been prime candidates for long. Here, we applied optogenetic
stimulation of HS cells to evaluate their behavioral role in Drosophila. To minimize
interference of the optical activation of channelrhodopsin-2 with the visual perception
of the flies, we used a bistable variant called ChR2-C128S. By applying pulses
of blue and yellow light, we first demonstrate electrophysiologically that lobula
plate tangential cells can be activated and deactivated repeatedly with no evident
change in depolarization strength over trials. We next show that selective optogenetic
activation of HS cells elicits robust yaw head movements and yaw turning responses
in fixed and tethered flying flies, respectively.
acknowledgement: 'This work was supported by the Max Planck Society. '
author:
- first_name: Väinö
full_name: Haikala, Väinö
last_name: Haikala
- first_name: Maximilian A
full_name: Maximilian Jösch
id: 2BD278E6-F248-11E8-B48F-1D18A9856A87
last_name: Jösch
orcid: 0000-0002-3937-1330
- first_name: Alexander
full_name: Borst, Alexander
last_name: Borst
- first_name: Alex
full_name: Mauss, Alex S
last_name: Mauss
citation:
ama: Haikala V, Jösch MA, Borst A, Mauss A. Optogenetic control of fly optomotor
responses. Journal of Neuroscience. 2013;33(34):13927-13934. doi:10.1523/JNEUROSCI.0340-13.2013
apa: Haikala, V., Jösch, M. A., Borst, A., & Mauss, A. (2013). Optogenetic control
of fly optomotor responses. Journal of Neuroscience. Society for Neuroscience.
https://doi.org/10.1523/JNEUROSCI.0340-13.2013
chicago: Haikala, Väinö, Maximilian A Jösch, Alexander Borst, and Alex Mauss. “Optogenetic
Control of Fly Optomotor Responses.” Journal of Neuroscience. Society for
Neuroscience, 2013. https://doi.org/10.1523/JNEUROSCI.0340-13.2013.
ieee: V. Haikala, M. A. Jösch, A. Borst, and A. Mauss, “Optogenetic control of fly
optomotor responses,” Journal of Neuroscience, vol. 33, no. 34. Society
for Neuroscience, pp. 13927–13934, 2013.
ista: Haikala V, Jösch MA, Borst A, Mauss A. 2013. Optogenetic control of fly optomotor
responses. Journal of Neuroscience. 33(34), 13927–13934.
mla: Haikala, Väinö, et al. “Optogenetic Control of Fly Optomotor Responses.” Journal
of Neuroscience, vol. 33, no. 34, Society for Neuroscience, 2013, pp. 13927–34,
doi:10.1523/JNEUROSCI.0340-13.2013.
short: V. Haikala, M.A. Jösch, A. Borst, A. Mauss, Journal of Neuroscience 33 (2013)
13927–13934.
date_created: 2018-12-11T11:51:16Z
date_published: 2013-01-01T00:00:00Z
date_updated: 2021-01-12T06:49:45Z
day: '01'
doi: 10.1523/JNEUROSCI.0340-13.2013
extern: 1
intvolume: ' 33'
issue: '34'
month: '01'
page: 13927 - 13934
publication: Journal of Neuroscience
publication_status: published
publisher: Society for Neuroscience
publist_id: '5967'
quality_controlled: 0
status: public
title: Optogenetic control of fly optomotor responses
type: journal_article
volume: 33
year: '2013'
...
---
_id: '1305'
abstract:
- lang: eng
text: In the fly Drosophila melanogaster, photoreceptor input to motion vision is
split into two parallel pathways as represented by first-order interneurons L1
and L2 (Rister et al., 2007; Joesch et al., 2010). However, how these pathways
are functionally specialized remains controversial. One study (Eichner et al.,
2011) proposed that the L1-pathway evaluates only sequences of brightness increments
(ON-ON), while the L2-pathway processes exclusively brightness decrements (OFF-OFF).
Another study (Clark et al., 2011) proposed that each of the two pathways evaluates
both ON-ON and OFF-OFF sequences. To decide between these alternatives, we recorded
from motionsensitive neurons in flies in which the output from either L1 or L2
was genetically blocked. We found that blocking L1 abolishes ON-ON responses but
leaves OFF-OFF responses intact. The opposite was true, when the output from L2
was blocked. We conclude that the L1 and L2 pathways are functionally specialized
to detect ON-ON and OFF-OFF sequences, respectively.
acknowledgement: This work was supported by the Max-Planck-Society and the SFB 870
of the Deutsche Forschungsgemeinschaft.
author:
- first_name: Maximilian A
full_name: Maximilian Jösch
id: 2BD278E6-F248-11E8-B48F-1D18A9856A87
last_name: Jösch
orcid: 0000-0002-3937-1330
- first_name: Franz
full_name: Weber, Franz
last_name: Weber
- first_name: Hubert
full_name: Eichner, Hubert
last_name: Eichner
- first_name: Alexander
full_name: Borst, Alexander
last_name: Borst
citation:
ama: Jösch MA, Weber F, Eichner H, Borst A. Functional specialization of parallel
motion detection circuits in the fly. Journal of Neuroscience. 2013;33(3):902-905.
doi:10.1523/JNEUROSCI.3374-12.2013
apa: Jösch, M. A., Weber, F., Eichner, H., & Borst, A. (2013). Functional specialization
of parallel motion detection circuits in the fly. Journal of Neuroscience.
Society for Neuroscience. https://doi.org/10.1523/JNEUROSCI.3374-12.2013
chicago: Jösch, Maximilian A, Franz Weber, Hubert Eichner, and Alexander Borst.
“Functional Specialization of Parallel Motion Detection Circuits in the Fly.”
Journal of Neuroscience. Society for Neuroscience, 2013. https://doi.org/10.1523/JNEUROSCI.3374-12.2013.
ieee: M. A. Jösch, F. Weber, H. Eichner, and A. Borst, “Functional specialization
of parallel motion detection circuits in the fly,” Journal of Neuroscience,
vol. 33, no. 3. Society for Neuroscience, pp. 902–905, 2013.
ista: Jösch MA, Weber F, Eichner H, Borst A. 2013. Functional specialization of
parallel motion detection circuits in the fly. Journal of Neuroscience. 33(3),
902–905.
mla: Jösch, Maximilian A., et al. “Functional Specialization of Parallel Motion
Detection Circuits in the Fly.” Journal of Neuroscience, vol. 33, no. 3,
Society for Neuroscience, 2013, pp. 902–05, doi:10.1523/JNEUROSCI.3374-12.2013.
short: M.A. Jösch, F. Weber, H. Eichner, A. Borst, Journal of Neuroscience 33 (2013)
902–905.
date_created: 2018-12-11T11:51:16Z
date_published: 2013-01-16T00:00:00Z
date_updated: 2021-01-12T06:49:45Z
day: '16'
doi: 10.1523/JNEUROSCI.3374-12.2013
extern: 1
intvolume: ' 33'
issue: '3'
month: '01'
page: 902 - 905
publication: Journal of Neuroscience
publication_status: published
publisher: Society for Neuroscience
publist_id: '5968'
quality_controlled: 0
status: public
title: Functional specialization of parallel motion detection circuits in the fly
type: journal_article
volume: 33
year: '2013'
...
---
_id: '1307'
abstract:
- lang: eng
text: We prove uniqueness of solutions of the DLSS equation in a class of sufficiently
regular functions. The global weak solutions of the DLSS equation constructed
by Jüngel and Matthes belong to this class of uniqueness. We also show uniqueness
of solutions for the quantum drift-diffusion equation, which contains additional
drift and second-order diffusion terms. The results hold in case of periodic or
Dirichlet-Neumann boundary conditions. Our proof is based on a monotonicity property
of the DLSS operator and sophisticated approximation arguments; we derive a PDE
satisfied by the pointwise square root of the solution, which enables us to exploit
the monotonicity property of the operator.
author:
- first_name: Julian L
full_name: Julian Fischer
id: 2C12A0B0-F248-11E8-B48F-1D18A9856A87
last_name: Fischer
orcid: 0000-0002-0479-558X
citation:
ama: Fischer JL. Uniqueness of solutions of the Derrida-Lebowitz-Speer-Spohn equation
and quantum drift diffusion models. Communications in Partial Differential
Equations. 2013;38(11):2004-2047. doi:10.1080/03605302.2013.823548
apa: Fischer, J. L. (2013). Uniqueness of solutions of the Derrida-Lebowitz-Speer-Spohn
equation and quantum drift diffusion models. Communications in Partial Differential
Equations. Taylor & Francis. https://doi.org/10.1080/03605302.2013.823548
chicago: Fischer, Julian L. “Uniqueness of Solutions of the Derrida-Lebowitz-Speer-Spohn
Equation and Quantum Drift Diffusion Models.” Communications in Partial Differential
Equations. Taylor & Francis, 2013. https://doi.org/10.1080/03605302.2013.823548.
ieee: J. L. Fischer, “Uniqueness of solutions of the Derrida-Lebowitz-Speer-Spohn
equation and quantum drift diffusion models,” Communications in Partial Differential
Equations, vol. 38, no. 11. Taylor & Francis, pp. 2004–2047, 2013.
ista: Fischer JL. 2013. Uniqueness of solutions of the Derrida-Lebowitz-Speer-Spohn
equation and quantum drift diffusion models. Communications in Partial Differential
Equations. 38(11), 2004–2047.
mla: Fischer, Julian L. “Uniqueness of Solutions of the Derrida-Lebowitz-Speer-Spohn
Equation and Quantum Drift Diffusion Models.” Communications in Partial Differential
Equations, vol. 38, no. 11, Taylor & Francis, 2013, pp. 2004–47, doi:10.1080/03605302.2013.823548.
short: J.L. Fischer, Communications in Partial Differential Equations 38 (2013)
2004–2047.
date_created: 2018-12-11T11:51:17Z
date_published: 2013-11-01T00:00:00Z
date_updated: 2021-01-12T06:49:46Z
day: '01'
doi: 10.1080/03605302.2013.823548
extern: 1
intvolume: ' 38'
issue: '11'
month: '11'
page: 2004 - 2047
publication: Communications in Partial Differential Equations
publication_status: published
publisher: Taylor & Francis
publist_id: '5962'
quality_controlled: 0
status: public
title: Uniqueness of solutions of the Derrida-Lebowitz-Speer-Spohn equation and quantum
drift diffusion models
type: journal_article
volume: 38
year: '2013'
...
---
_id: '1308'
abstract:
- lang: eng
text: We derive sufficient conditions for advection-driven backward motion of the
free boundary in a chemotaxis model with degenerate mobility. In this model, a
porous-medium-type diffusive term and an advection term are in competition. The
former induces forward motion, the latter may induce backward motion of the free
boundary depending on the direction of advection. We deduce conditions on the
growth of the initial data at the free boundary which ensure that at least initially
the advection term is dominant. This implies local backward motion of the free
boundary provided the advection is (locally) directed appropriately. Our result
is based on a new class of moving test functions and Stampacchia's lemma. As a
by-product of our estimates, we obtain quantitative bounds on the spreading of
the support of solutions for the chemotaxis model and provide a proof for the
finite speed of the support propagation property of solutions.
author:
- first_name: Julian L
full_name: Julian Fischer
id: 2C12A0B0-F248-11E8-B48F-1D18A9856A87
last_name: Fischer
orcid: 0000-0002-0479-558X
citation:
ama: Fischer JL. Advection-driven support shrinking in a chemotaxis model with degenerate
mobility. SIAM Journal on Mathematical Analysis. 2013;45(3):1585-1615.
doi:10.1137/120874291
apa: Fischer, J. L. (2013). Advection-driven support shrinking in a chemotaxis model
with degenerate mobility. SIAM Journal on Mathematical Analysis. Society
for Industrial and Applied Mathematics . https://doi.org/10.1137/120874291
chicago: Fischer, Julian L. “Advection-Driven Support Shrinking in a Chemotaxis
Model with Degenerate Mobility.” SIAM Journal on Mathematical Analysis.
Society for Industrial and Applied Mathematics , 2013. https://doi.org/10.1137/120874291.
ieee: J. L. Fischer, “Advection-driven support shrinking in a chemotaxis model with
degenerate mobility,” SIAM Journal on Mathematical Analysis, vol. 45, no.
3. Society for Industrial and Applied Mathematics , pp. 1585–1615, 2013.
ista: Fischer JL. 2013. Advection-driven support shrinking in a chemotaxis model
with degenerate mobility. SIAM Journal on Mathematical Analysis. 45(3), 1585–1615.
mla: Fischer, Julian L. “Advection-Driven Support Shrinking in a Chemotaxis Model
with Degenerate Mobility.” SIAM Journal on Mathematical Analysis, vol.
45, no. 3, Society for Industrial and Applied Mathematics , 2013, pp. 1585–615,
doi:10.1137/120874291.
short: J.L. Fischer, SIAM Journal on Mathematical Analysis 45 (2013) 1585–1615.
date_created: 2018-12-11T11:51:17Z
date_published: 2013-01-01T00:00:00Z
date_updated: 2021-01-12T06:49:46Z
day: '01'
doi: 10.1137/120874291
extern: 1
intvolume: ' 45'
issue: '3'
month: '01'
page: 1585 - 1615
publication: SIAM Journal on Mathematical Analysis
publication_status: published
publisher: 'Society for Industrial and Applied Mathematics '
publist_id: '5963'
quality_controlled: 0
status: public
title: Advection-driven support shrinking in a chemotaxis model with degenerate mobility
type: journal_article
volume: 45
year: '2013'
...
---
_id: '1310'
abstract:
- lang: eng
text: We derive lower bounds on asymptotic support propagation rates for strong
solutions of the Cauchy problem for the thin-film equation. The bounds coincide
up to a constant factor with the previously known upper bounds and thus are sharp.
Our results hold in case of at most three spatial dimensions and n∈. (1, 2.92).
The result is established using weighted backward entropy inequalities with singular
weight functions to yield a differential inequality; combined with some entropy
production estimates, the optimal rate of propagation is obtained. To the best
of our knowledge, these are the first lower bounds on asymptotic support propagation
rates for higher-order nonnegativity-preserving parabolic equations.
author:
- first_name: Julian L
full_name: Julian Fischer
id: 2C12A0B0-F248-11E8-B48F-1D18A9856A87
last_name: Fischer
orcid: 0000-0002-0479-558X
citation:
ama: Fischer JL. Optimal lower bounds on asymptotic support propagation rates for
the thin-film equation. Journal of Differential Equations. 2013;255(10):3127-3149.
doi:10.1016/j.jde.2013.07.028
apa: Fischer, J. L. (2013). Optimal lower bounds on asymptotic support propagation
rates for the thin-film equation. Journal of Differential Equations. Academic
Press. https://doi.org/10.1016/j.jde.2013.07.028
chicago: Fischer, Julian L. “Optimal Lower Bounds on Asymptotic Support Propagation
Rates for the Thin-Film Equation.” Journal of Differential Equations. Academic
Press, 2013. https://doi.org/10.1016/j.jde.2013.07.028.
ieee: J. L. Fischer, “Optimal lower bounds on asymptotic support propagation rates
for the thin-film equation,” Journal of Differential Equations, vol. 255,
no. 10. Academic Press, pp. 3127–3149, 2013.
ista: Fischer JL. 2013. Optimal lower bounds on asymptotic support propagation rates
for the thin-film equation. Journal of Differential Equations. 255(10), 3127–3149.
mla: Fischer, Julian L. “Optimal Lower Bounds on Asymptotic Support Propagation
Rates for the Thin-Film Equation.” Journal of Differential Equations, vol.
255, no. 10, Academic Press, 2013, pp. 3127–49, doi:10.1016/j.jde.2013.07.028.
short: J.L. Fischer, Journal of Differential Equations 255 (2013) 3127–3149.
date_created: 2018-12-11T11:51:18Z
date_published: 2013-11-15T00:00:00Z
date_updated: 2021-01-12T06:49:47Z
day: '15'
doi: 10.1016/j.jde.2013.07.028
extern: 1
intvolume: ' 255'
issue: '10'
month: '11'
page: 3127 - 3149
publication: Journal of Differential Equations
publication_status: published
publisher: Academic Press
publist_id: '5961'
quality_controlled: 0
status: public
title: Optimal lower bounds on asymptotic support propagation rates for the thin-film
equation
type: journal_article
volume: 255
year: '2013'
...
---
_id: '1978'
abstract:
- lang: eng
text: Complex I is the first and largest enzyme of the respiratory chain and has
a central role in cellular energy production through the coupling of NADH:ubiquinone
electron transfer to proton translocation. It is also implicated in many common
human neurodegenerative diseases. Here, we report the first crystal structure
of the entire, intact complex I (from Thermus thermophilus) at 3.3 Å resolution.
The structure of the 536-kDa complex comprises 16 different subunits, with a total
of 64 transmembrane helices and 9 iron-sulphur clusters. The core fold of subunit
Nqo8 (ND1 in humans) is, unexpectedly, similar to a half-channel of the antiporter-like
subunits. Small subunits nearby form a linked second half-channel, which completes
the fourth proton-translocation pathway (present in addition to the channels in
three antiporter-like subunits). The quinone-binding site is unusually long, narrow
and enclosed. The quinone headgroup binds at the deep end of this chamber, near
iron-sulphur cluster N2. Notably, the chamber is linked to the fourth channel
by a 'funnel' of charged residues. The link continues over the entire membrane
domain as a flexible central axis of charged and polar residues, and probably
has a leading role in the propagation of conformational changes, aided by coupling
elements. The structure suggests that a unique, out-of-the-membrane quinone-reaction
chamber enables the redox energy to drive concerted long-range conformational
changes in the four antiporter-like domains, resulting in translocation of four
protons per cycle.
acknowledgement: This work was funded by the Medical Research Council.
author:
- first_name: Rozbeh
full_name: 'Baradaran, Rozbeh '
last_name: Baradaran
- first_name: John
full_name: Berrisford, John M
last_name: Berrisford
- first_name: Gurdeep
full_name: Minhas, Gurdeep S
last_name: Minhas
- first_name: Leonid A
full_name: Leonid Sazanov
id: 338D39FE-F248-11E8-B48F-1D18A9856A87
last_name: Sazanov
orcid: 0000-0002-0977-7989
citation:
ama: Baradaran R, Berrisford J, Minhas G, Sazanov LA. Crystal structure of the entire
respiratory complex i. Nature. 2013;494(7438):443-448. doi:10.1038/nature11871
apa: Baradaran, R., Berrisford, J., Minhas, G., & Sazanov, L. A. (2013). Crystal
structure of the entire respiratory complex i. Nature. Nature Publishing
Group. https://doi.org/10.1038/nature11871
chicago: Baradaran, Rozbeh, John Berrisford, Gurdeep Minhas, and Leonid A Sazanov.
“Crystal Structure of the Entire Respiratory Complex I.” Nature. Nature
Publishing Group, 2013. https://doi.org/10.1038/nature11871.
ieee: R. Baradaran, J. Berrisford, G. Minhas, and L. A. Sazanov, “Crystal structure
of the entire respiratory complex i,” Nature, vol. 494, no. 7438. Nature
Publishing Group, pp. 443–448, 2013.
ista: Baradaran R, Berrisford J, Minhas G, Sazanov LA. 2013. Crystal structure of
the entire respiratory complex i. Nature. 494(7438), 443–448.
mla: Baradaran, Rozbeh, et al. “Crystal Structure of the Entire Respiratory Complex
I.” Nature, vol. 494, no. 7438, Nature Publishing Group, 2013, pp. 443–48,
doi:10.1038/nature11871.
short: R. Baradaran, J. Berrisford, G. Minhas, L.A. Sazanov, Nature 494 (2013) 443–448.
date_created: 2018-12-11T11:55:01Z
date_published: 2013-02-28T00:00:00Z
date_updated: 2021-01-12T06:54:28Z
day: '28'
doi: 10.1038/nature11871
extern: 1
intvolume: ' 494'
issue: '7438'
month: '02'
page: 443 - 448
publication: Nature
publication_status: published
publisher: Nature Publishing Group
publist_id: '5107'
quality_controlled: 0
status: public
title: Crystal structure of the entire respiratory complex i
type: journal_article
volume: 494
year: '2013'
...
---
_id: '1988'
abstract:
- lang: eng
text: The rod-shaped bacterium Escherichia coli selects the cell center as site
of division with the help of the proteins MinC, MinD, and MinE. This protein system
collectively oscillates between the two cell poles by alternately binding to the
membrane in one of the two cell halves. This dynamic behavior, which emerges from
the interaction of the ATPase MinD and its activator MinE on the cell membrane,
has become a paradigm for protein self-organization. Recently, it has been found
that not only the binding of MinD to the membrane, but also interactions of MinE
with the membrane contribute to Min-protein self-organization. Here, we show that
by accounting for this finding in a computational model, we can comprehensively
describe all observed Min-protein patterns in vivo and in vitro. Furthermore,
by varying the system's geometry, our computations predict patterns that have
not yet been reported. We confirm these predictions experimentally.
author:
- first_name: Mike
full_name: 'Bonny, Mike '
last_name: Bonny
- first_name: Elisabeth
full_name: Fischer-Friedrich, Elisabeth
last_name: Fischer Friedrich
- first_name: Martin
full_name: Martin Loose
id: 462D4284-F248-11E8-B48F-1D18A9856A87
last_name: Loose
orcid: 0000-0001-7309-9724
- first_name: Petra
full_name: 'Schwille, Petra '
last_name: Schwille
- first_name: Karsten
full_name: Kruse, Karsten
last_name: Kruse
citation:
ama: Bonny M, Fischer Friedrich E, Loose M, Schwille P, Kruse K. Membrane binding
of MinE allows for a comprehensive description of Min-protein pattern formation.
PLoS Computational Biology. 2013;9(12). doi:10.1371/journal.pcbi.1003347
apa: Bonny, M., Fischer Friedrich, E., Loose, M., Schwille, P., & Kruse, K.
(2013). Membrane binding of MinE allows for a comprehensive description of Min-protein
pattern formation. PLoS Computational Biology. Public Library of Science.
https://doi.org/10.1371/journal.pcbi.1003347
chicago: Bonny, Mike, Elisabeth Fischer Friedrich, Martin Loose, Petra Schwille,
and Karsten Kruse. “Membrane Binding of MinE Allows for a Comprehensive Description
of Min-Protein Pattern Formation.” PLoS Computational Biology. Public Library
of Science, 2013. https://doi.org/10.1371/journal.pcbi.1003347.
ieee: M. Bonny, E. Fischer Friedrich, M. Loose, P. Schwille, and K. Kruse, “Membrane
binding of MinE allows for a comprehensive description of Min-protein pattern
formation,” PLoS Computational Biology, vol. 9, no. 12. Public Library
of Science, 2013.
ista: Bonny M, Fischer Friedrich E, Loose M, Schwille P, Kruse K. 2013. Membrane
binding of MinE allows for a comprehensive description of Min-protein pattern
formation. PLoS Computational Biology. 9(12).
mla: Bonny, Mike, et al. “Membrane Binding of MinE Allows for a Comprehensive Description
of Min-Protein Pattern Formation.” PLoS Computational Biology, vol. 9,
no. 12, Public Library of Science, 2013, doi:10.1371/journal.pcbi.1003347.
short: M. Bonny, E. Fischer Friedrich, M. Loose, P. Schwille, K. Kruse, PLoS Computational
Biology 9 (2013).
date_created: 2018-12-11T11:55:04Z
date_published: 2013-12-01T00:00:00Z
date_updated: 2021-01-12T06:54:32Z
day: '01'
doi: 10.1371/journal.pcbi.1003347
extern: 1
intvolume: ' 9'
issue: '12'
month: '12'
publication: PLoS Computational Biology
publication_status: published
publisher: Public Library of Science
publist_id: '5095'
quality_controlled: 0
status: public
title: Membrane binding of MinE allows for a comprehensive description of Min-protein
pattern formation
type: journal_article
volume: 9
year: '2013'
...
---
_id: '1991'
abstract:
- lang: eng
text: Although transitions of sex-determination mechanisms are frequent in species
with homomorphic sex chromosomes, heteromorphic sex chromosomes are thought to
represent a terminal evolutionary stage owing to chromosome-specific adaptations
such as dosage compensation or an accumulation of sex-specific mutations. Here
we show that an autosome of Drosophila, the dot chromosome, was ancestrally a
differentiated X chromosome. We analyse the whole genome of true fruitflies (Tephritidae),
flesh flies (Sarcophagidae) and soldier flies (Stratiomyidae) to show that genes
located on the dot chromosome of Drosophila are X-linked in outgroup species,
whereas Drosophila X-linked genes are autosomal. We date this chromosomal transition
to early drosophilid evolution by sequencing the genome of other Drosophilidae.
Our results reveal several puzzling aspects of Drosophila dot chromosome biology
to be possible remnants of its former life as a sex chromosome, such as its minor
feminizing role in sex determination or its targeting by a chromosome-specific
regulatory mechanism. We also show that patterns of biased gene expression of
the dot chromosome during early embryogenesis, oogenesis and spermatogenesis resemble
that of the current X chromosome. Thus, although sex chromosomes are not necessarily
evolutionary end points and can revert back to an autosomal inheritance, the highly
specialized genome architecture of this former X chromosome suggests that severe
fitness costs must be overcome for such a turnover to occur.
acknowledgement: Funded by National Institutes of Health grants (R01GM076007 and R01GM093182)
and a Packard Fellowship to D.B.
author:
- first_name: Beatriz
full_name: Beatriz Vicoso
id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
last_name: Vicoso
orcid: 0000-0002-4579-8306
- first_name: Doris
full_name: Bachtrog, Doris
last_name: Bachtrog
citation:
ama: Vicoso B, Bachtrog D. Reversal of an ancient sex chromosome to an autosome
in Drosophila. Nature. 2013;499(7458):332-335. doi:10.1038/nature12235
apa: Vicoso, B., & Bachtrog, D. (2013). Reversal of an ancient sex chromosome
to an autosome in Drosophila. Nature. Nature Publishing Group. https://doi.org/10.1038/nature12235
chicago: Vicoso, Beatriz, and Doris Bachtrog. “Reversal of an Ancient Sex Chromosome
to an Autosome in Drosophila.” Nature. Nature Publishing Group, 2013. https://doi.org/10.1038/nature12235.
ieee: B. Vicoso and D. Bachtrog, “Reversal of an ancient sex chromosome to an autosome
in Drosophila,” Nature, vol. 499, no. 7458. Nature Publishing Group, pp.
332–335, 2013.
ista: Vicoso B, Bachtrog D. 2013. Reversal of an ancient sex chromosome to an autosome
in Drosophila. Nature. 499(7458), 332–335.
mla: Vicoso, Beatriz, and Doris Bachtrog. “Reversal of an Ancient Sex Chromosome
to an Autosome in Drosophila.” Nature, vol. 499, no. 7458, Nature Publishing
Group, 2013, pp. 332–35, doi:10.1038/nature12235.
short: B. Vicoso, D. Bachtrog, Nature 499 (2013) 332–335.
date_created: 2018-12-11T11:55:05Z
date_published: 2013-07-18T00:00:00Z
date_updated: 2021-01-12T06:54:33Z
day: '18'
doi: 10.1038/nature12235
extern: 1
intvolume: ' 499'
issue: '7458'
month: '07'
page: 332 - 335
publication: Nature
publication_status: published
publisher: Nature Publishing Group
publist_id: '5092'
quality_controlled: 0
status: public
title: Reversal of an ancient sex chromosome to an autosome in Drosophila
type: journal_article
volume: 499
year: '2013'
...
---
OA_place: repository
OA_type: green
_id: '19995'
abstract:
- lang: eng
text: Markov decision processes (MDPs) and simple stochastic games (SSGs) provide
a rich mathematical framework to study many important problems related to probabilistic
systems. MDPs and SSGs with finite-horizon objectives, where the goal is to maximize
the probability to reach a target state in a given finite time, is a classical
and well-studied problem. In this work we consider the strategy complexity of
finite-horizon MDPs and SSGs. We show that for all ε > 0, the natural class of
counter-based strategies require at most log log/(1/ε) + n + 1 memory states,
and memory of size Omega(log log(1/ε) + n) is required, for ε-optimality, where
n is the number of states of the MDP (resp. SSG). Thus our bounds are asymptotically
optimal. We then study the periodic property of optimal strategies, and show a
sub-exponential lower bound on the period for optimal strategies.
acknowledgement: 'Work of the second author supported by the Sino-Danish Center for
the Theory of Interactive Computation, funded by the Danish National Research Foundation
and the National Science Foundation of China (under the grant 61061130540). The
second author acknowledge support from the Center for research in the Foundations
of Electronic Markets (CFEM), supported by the Danish Strategic Research Council.
The first author was supported by FWF Grant No P 23499-N23, FWF NFN Grant No S11407-N23
(RiSE), ERC Start grant (279307: Graph Games), and Microsoft faculty fellows award.'
alternative_title:
- LNCS
article_processing_charge: No
arxiv: 1
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Rasmus
full_name: Ibsen-Jensen, Rasmus
id: 3B699956-F248-11E8-B48F-1D18A9856A87
last_name: Ibsen-Jensen
orcid: 0000-0003-4783-0389
citation:
ama: 'Chatterjee K, Ibsen-Jensen R. Strategy complexity of finite-horizon Markov
decision processes and simple stochastic games. In: Mathematical and Engineering
Methods in Computer Science. Vol 7721. Springer Nature; 2013:106-117. doi:10.1007/978-3-642-36046-6_11'
apa: 'Chatterjee, K., & Ibsen-Jensen, R. (2013). Strategy complexity of finite-horizon
Markov decision processes and simple stochastic games. In Mathematical and
Engineering Methods in Computer Science (Vol. 7721, pp. 106–117). Znojmo,
Czech Republic: Springer Nature. https://doi.org/10.1007/978-3-642-36046-6_11'
chicago: Chatterjee, Krishnendu, and Rasmus Ibsen-Jensen. “Strategy Complexity of
Finite-Horizon Markov Decision Processes and Simple Stochastic Games.” In Mathematical
and Engineering Methods in Computer Science, 7721:106–17. Springer Nature,
2013. https://doi.org/10.1007/978-3-642-36046-6_11.
ieee: K. Chatterjee and R. Ibsen-Jensen, “Strategy complexity of finite-horizon
Markov decision processes and simple stochastic games,” in Mathematical and
Engineering Methods in Computer Science, Znojmo, Czech Republic, 2013, vol.
7721, pp. 106–117.
ista: 'Chatterjee K, Ibsen-Jensen R. 2013. Strategy complexity of finite-horizon
Markov decision processes and simple stochastic games. Mathematical and Engineering
Methods in Computer Science. MEMICS: Mathematical and Engineering Methods in Computer
Science, LNCS, vol. 7721, 106–117.'
mla: Chatterjee, Krishnendu, and Rasmus Ibsen-Jensen. “Strategy Complexity of Finite-Horizon
Markov Decision Processes and Simple Stochastic Games.” Mathematical and Engineering
Methods in Computer Science, vol. 7721, Springer Nature, 2013, pp. 106–17,
doi:10.1007/978-3-642-36046-6_11.
short: K. Chatterjee, R. Ibsen-Jensen, in:, Mathematical and Engineering Methods
in Computer Science, Springer Nature, 2013, pp. 106–117.
conference:
end_date: 2012-10-28
location: Znojmo, Czech Republic
name: 'MEMICS: Mathematical and Engineering Methods in Computer Science'
start_date: 2012-10-25
corr_author: '1'
date_created: 2025-07-10T14:08:49Z
date_published: 2013-01-17T00:00:00Z
date_updated: 2025-09-23T09:24:13Z
day: '17'
department:
- _id: KrCh
doi: 10.1007/978-3-642-36046-6_11
ec_funded: 1
external_id:
arxiv:
- '1209.3617'
intvolume: ' 7721'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.1209.3617
month: '01'
oa: 1
oa_version: Preprint
page: 106-117
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
publication: Mathematical and Engineering Methods in Computer Science
publication_identifier:
eisbn:
- '9783642360466'
eissn:
- 1611-3349
isbn:
- '9783642360442'
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Strategy complexity of finite-horizon Markov decision processes and simple
stochastic games
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7721
year: '2013'
...
---
_id: '2009'
abstract:
- lang: eng
text: Traditional statistical methods for confidentiality protection of statistical
databases do not scale well to deal with GWAS databases especially in terms of
guarantees regarding protection from linkage to external information. The more
recent concept of differential privacy, introduced by the cryptographic community,
is an approach which provides a rigorous definition of privacy with meaningful
privacy guarantees in the presence of arbitrary external information, although
the guarantees may come at a serious price in terms of data utility. Building
on such notions, we propose new methods to release aggregate GWAS data without
compromising an individual’s privacy. We present methods for releasing differentially
private minor allele frequencies, chi-square statistics and p-values. We compare
these approaches on simulated data and on a GWAS study of canine hair length involving
685 dogs. We also propose a privacy-preserving method for finding genome-wide
associations based on a differentially-private approach to penalized logistic
regression.
article_processing_charge: No
author:
- first_name: Caroline
full_name: Uhler, Caroline
id: 49ADD78E-F248-11E8-B48F-1D18A9856A87
last_name: Uhler
orcid: 0000-0002-7008-0216
- first_name: Aleksandra
full_name: Slavkovic, Aleksandra
last_name: Slavkovic
- first_name: Stephen
full_name: Fienberg, Stephen
last_name: Fienberg
citation:
ama: Uhler C, Slavkovic A, Fienberg S. Privacy-preserving data sharing for genome-wide
association studies. Journal of Privacy and Confidentiality . 2013;5(1):137-166.
doi:10.29012/jpc.v5i1.629
apa: Uhler, C., Slavkovic, A., & Fienberg, S. (2013). Privacy-preserving data
sharing for genome-wide association studies. Journal of Privacy and Confidentiality
. Carnegie Mellon University. https://doi.org/10.29012/jpc.v5i1.629
chicago: Uhler, Caroline, Aleksandra Slavkovic, and Stephen Fienberg. “Privacy-Preserving
Data Sharing for Genome-Wide Association Studies.” Journal of Privacy and Confidentiality
. Carnegie Mellon University, 2013. https://doi.org/10.29012/jpc.v5i1.629.
ieee: C. Uhler, A. Slavkovic, and S. Fienberg, “Privacy-preserving data sharing
for genome-wide association studies,” Journal of Privacy and Confidentiality
, vol. 5, no. 1. Carnegie Mellon University, pp. 137–166, 2013.
ista: Uhler C, Slavkovic A, Fienberg S. 2013. Privacy-preserving data sharing for
genome-wide association studies. Journal of Privacy and Confidentiality . 5(1),
137–166.
mla: Uhler, Caroline, et al. “Privacy-Preserving Data Sharing for Genome-Wide Association
Studies.” Journal of Privacy and Confidentiality , vol. 5, no. 1, Carnegie
Mellon University, 2013, pp. 137–66, doi:10.29012/jpc.v5i1.629.
short: C. Uhler, A. Slavkovic, S. Fienberg, Journal of Privacy and Confidentiality 5
(2013) 137–166.
date_created: 2018-12-11T11:55:11Z
date_published: 2013-08-01T00:00:00Z
date_updated: 2021-01-12T06:54:41Z
day: '01'
department:
- _id: CaUh
doi: 10.29012/jpc.v5i1.629
intvolume: ' 5'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://repository.cmu.edu/jpc/vol5/iss1/6
month: '08'
oa: 1
oa_version: Published Version
page: 137 - 166
publication: 'Journal of Privacy and Confidentiality '
publication_status: published
publisher: Carnegie Mellon University
publist_id: '5067'
quality_controlled: '1'
status: public
title: Privacy-preserving data sharing for genome-wide association studies
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2013'
...
---
_id: '2010'
abstract:
- lang: eng
text: Many algorithms for inferring causality rely heavily on the faithfulness assumption.
The main justification for imposing this assumption is that the set of unfaithful
distributions has Lebesgue measure zero, since it can be seen as a collection
of hypersurfaces in a hypercube. However, due to sampling error the faithfulness
condition alone is not sufficient for statistical estimation, and strong-faithfulness
has been proposed and assumed to achieve uniform or high-dimensional consistency.
In contrast to the plain faithfulness assumption, the set of distributions that
is not strong-faithful has nonzero Lebesgue measure and in fact, can be surprisingly
large as we show in this paper. We study the strong-faithfulness condition from
a geometric and combinatorial point of view and give upper and lower bounds on
the Lebesgue measure of strong-faithful distributions for various classes of directed
acyclic graphs. Our results imply fundamental limitations for the PC-algorithm
and potentially also for other algorithms based on partial correlation testing
in the Gaussian case.
article_processing_charge: No
arxiv: 1
author:
- first_name: Caroline
full_name: Uhler, Caroline
id: 49ADD78E-F248-11E8-B48F-1D18A9856A87
last_name: Uhler
orcid: 0000-0002-7008-0216
- first_name: Garvesh
full_name: Raskutti, Garvesh
last_name: Raskutti
- first_name: Peter
full_name: Bühlmann, Peter
last_name: Bühlmann
- first_name: Bin
full_name: Yu, Bin
last_name: Yu
citation:
ama: Uhler C, Raskutti G, Bühlmann P, Yu B. Geometry of the faithfulness assumption
in causal inference. The Annals of Statistics. 2013;41(2):436-463. doi:10.1214/12-AOS1080
apa: Uhler, C., Raskutti, G., Bühlmann, P., & Yu, B. (2013). Geometry of the
faithfulness assumption in causal inference. The Annals of Statistics.
Institute of Mathematical Statistics. https://doi.org/10.1214/12-AOS1080
chicago: Uhler, Caroline, Garvesh Raskutti, Peter Bühlmann, and Bin Yu. “Geometry
of the Faithfulness Assumption in Causal Inference.” The Annals of Statistics.
Institute of Mathematical Statistics, 2013. https://doi.org/10.1214/12-AOS1080.
ieee: C. Uhler, G. Raskutti, P. Bühlmann, and B. Yu, “Geometry of the faithfulness
assumption in causal inference,” The Annals of Statistics, vol. 41, no.
2. Institute of Mathematical Statistics, pp. 436–463, 2013.
ista: Uhler C, Raskutti G, Bühlmann P, Yu B. 2013. Geometry of the faithfulness
assumption in causal inference. The Annals of Statistics. 41(2), 436–463.
mla: Uhler, Caroline, et al. “Geometry of the Faithfulness Assumption in Causal
Inference.” The Annals of Statistics, vol. 41, no. 2, Institute of Mathematical
Statistics, 2013, pp. 436–63, doi:10.1214/12-AOS1080.
short: C. Uhler, G. Raskutti, P. Bühlmann, B. Yu, The Annals of Statistics 41 (2013)
436–463.
date_created: 2018-12-11T11:55:11Z
date_published: 2013-04-01T00:00:00Z
date_updated: 2025-09-29T14:31:39Z
day: '01'
department:
- _id: CaUh
doi: 10.1214/12-AOS1080
external_id:
arxiv:
- '1207.0547'
isi:
- '000320488200002'
intvolume: ' 41'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: www.doi.org/10.1214/12-AOS1080
month: '04'
oa: 1
oa_version: Published Version
page: 436 - 463
publication: The Annals of Statistics
publication_status: published
publisher: Institute of Mathematical Statistics
publist_id: '5066'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Geometry of the faithfulness assumption in causal inference
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 41
year: '2013'
...
---
_id: '2074'
abstract:
- lang: eng
text: 'Sex chromosomes originate from autosomes. The accumulation of sexually antagonistic
mutations on protosex chromosomes selects for a loss of recombination and sets
in motion the evolutionary processes generating heteromorphic sex chromosomes.
Recombination suppression and differentiation are generally viewed as the default
path of sex chromosome evolution, and the occurrence of old, homomorphic sex chromosomes,
such as those of ratite birds, has remained a mystery. Here, we analyze the genome
and transcriptome of emu (Dromaius novaehollandiae) and confirm that most genes
on the sex chromosome are shared between the Z and W. Surprisingly, however, levels
of gene expression are generally sex-biased for all sex-linked genes relative
to autosomes, including those in the pseudoautosomal region, and the male-bias
increases after gonad formation. This expression bias suggests that the emu sex
chromosomes have become masculinized, even in the absence of ZW differentiation.
Thus, birds may have taken different evolutionary solutions to minimize the deleterious
effects imposed by sexually antagonistic mutations: some lineages eliminate recombination
along the protosex chromosomes to physically restrict sexually antagonistic alleles
to one sex, whereas ratites evolved sex-biased expression to confine the product
of a sexually antagonistic allele to the sex it benefits. This difference in conflict
resolution may explain the preservation of recombining, homomorphic sex chromosomes
in other lineages and illustrates the importance of sexually antagonistic mutations
driving the evolution of sex chromosomes. '
author:
- first_name: Beatriz
full_name: Beatriz Vicoso
id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
last_name: Vicoso
orcid: 0000-0002-4579-8306
- first_name: Vera
full_name: Kaiser, Vera B
last_name: Kaiser
- first_name: Doris
full_name: Bachtrog, Doris
last_name: Bachtrog
citation:
ama: Vicoso B, Kaiser V, Bachtrog D. Sex biased gene expression at homomorphic sex
chromosomes in emus and its implication for sex chromosome evolution. PNAS.
2013;110(16):6453-6458. doi:10.1073/pnas.1217027110
apa: Vicoso, B., Kaiser, V., & Bachtrog, D. (2013). Sex biased gene expression
at homomorphic sex chromosomes in emus and its implication for sex chromosome
evolution. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.1217027110
chicago: Vicoso, Beatriz, Vera Kaiser, and Doris Bachtrog. “Sex Biased Gene Expression
at Homomorphic Sex Chromosomes in Emus and Its Implication for Sex Chromosome
Evolution.” PNAS. National Academy of Sciences, 2013. https://doi.org/10.1073/pnas.1217027110.
ieee: B. Vicoso, V. Kaiser, and D. Bachtrog, “Sex biased gene expression at homomorphic
sex chromosomes in emus and its implication for sex chromosome evolution,” PNAS,
vol. 110, no. 16. National Academy of Sciences, pp. 6453–6458, 2013.
ista: Vicoso B, Kaiser V, Bachtrog D. 2013. Sex biased gene expression at homomorphic
sex chromosomes in emus and its implication for sex chromosome evolution. PNAS.
110(16), 6453–6458.
mla: Vicoso, Beatriz, et al. “Sex Biased Gene Expression at Homomorphic Sex Chromosomes
in Emus and Its Implication for Sex Chromosome Evolution.” PNAS, vol. 110,
no. 16, National Academy of Sciences, 2013, pp. 6453–58, doi:10.1073/pnas.1217027110.
short: B. Vicoso, V. Kaiser, D. Bachtrog, PNAS 110 (2013) 6453–6458.
date_created: 2018-12-11T11:55:33Z
date_published: 2013-04-16T00:00:00Z
date_updated: 2021-01-12T06:55:08Z
day: '16'
doi: 10.1073/pnas.1217027110
extern: 1
intvolume: ' 110'
issue: '16'
month: '04'
page: 6453 - 6458
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '4964'
quality_controlled: 0
status: public
title: Sex biased gene expression at homomorphic sex chromosomes in emus and its implication
for sex chromosome evolution
type: journal_article
volume: 110
year: '2013'
...
---
_id: '2076'
abstract:
- lang: eng
text: |
Snakes exhibit genetic sex determination, with female heterogametic sex chromosomes (ZZ males, ZW females). Extensive cytogenetic work has suggested that the level of sex chromosome heteromorphism varies among species, with Boidae having entirely homomorphic sex chromosomes, Viperidae having completely heteromorphic sex chromosomes, and Colubridae showing partial differentiation. Here, we take a genomic approach to compare sex chromosome differentiation in these three snake families. We identify homomorphic sex chromosomes in boas (Boidae), but completely heteromorphic sex chromosomes in both garter snakes (Colubridae) and pygmy rattlesnake (Viperidae). Detection of W-linked gametologs enables us to establish the presence of evolutionary strata on garter and pygmy rattlesnake sex chromosomes where recombination was abolished at different time points. Sequence analysis shows that all strata are shared between pygmy rattlesnake and garter snake, i.e., recombination was abolished between the sex chromosomes before the two lineages diverged. The sex-biased transmission of the Z and its hemizygosity in females can impact patterns of molecular evolution, and we show that rates of evolution for Z-linked genes are increased relative to their pseudoautosomal homologs, both at synonymous and amino acid sites (even after controlling for mutational biases). This demonstrates that mutation rates are male-biased in snakes (male-driven evolution), but also supports faster-Z evolution due to differential selective effects on the Z. Finally, we perform a transcriptome analysis in boa and pygmy rattlesnake to establish baseline levels of sex-biased expression in homomorphic sex chromosomes, and show that heteromorphic ZW chromosomes in rattlesnakes lack chromosome-wide dosage compensation. Our study provides the first full scale overview of the evolution of snake sex chromosomes at the genomic level, thus greatly expanding our knowledge of reptilian and vertebrate sex chromosomes evolution.
acknowledgement: Funded by NIH grants (R01GM076007 and R01GM093182) and a Packard
Fellowship to DB.
author:
- first_name: Beatriz
full_name: Beatriz Vicoso
id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
last_name: Vicoso
orcid: 0000-0002-4579-8306
- first_name: Jr
full_name: Emerson, Jr J.
last_name: Emerson
- first_name: Yulia
full_name: Zektser, Yulia
last_name: Zektser
- first_name: Shivani
full_name: Mahajan, Shivani
last_name: Mahajan
- first_name: Doris
full_name: Bachtrog, Doris
last_name: Bachtrog
citation:
ama: 'Vicoso B, Emerson J, Zektser Y, Mahajan S, Bachtrog D. Comparative sex chromosome
genomics in snakes: Differentiation evolutionary strata and lack of global dosage
compensation. PLoS Biology. 2013;11(8). doi:10.1371/journal.pbio.1001643'
apa: 'Vicoso, B., Emerson, J., Zektser, Y., Mahajan, S., & Bachtrog, D. (2013).
Comparative sex chromosome genomics in snakes: Differentiation evolutionary strata
and lack of global dosage compensation. PLoS Biology. Public Library of
Science. https://doi.org/10.1371/journal.pbio.1001643'
chicago: 'Vicoso, Beatriz, Jr Emerson, Yulia Zektser, Shivani Mahajan, and Doris
Bachtrog. “Comparative Sex Chromosome Genomics in Snakes: Differentiation Evolutionary
Strata and Lack of Global Dosage Compensation.” PLoS Biology. Public Library
of Science, 2013. https://doi.org/10.1371/journal.pbio.1001643.'
ieee: 'B. Vicoso, J. Emerson, Y. Zektser, S. Mahajan, and D. Bachtrog, “Comparative
sex chromosome genomics in snakes: Differentiation evolutionary strata and lack
of global dosage compensation,” PLoS Biology, vol. 11, no. 8. Public Library
of Science, 2013.'
ista: 'Vicoso B, Emerson J, Zektser Y, Mahajan S, Bachtrog D. 2013. Comparative
sex chromosome genomics in snakes: Differentiation evolutionary strata and lack
of global dosage compensation. PLoS Biology. 11(8).'
mla: 'Vicoso, Beatriz, et al. “Comparative Sex Chromosome Genomics in Snakes: Differentiation
Evolutionary Strata and Lack of Global Dosage Compensation.” PLoS Biology,
vol. 11, no. 8, Public Library of Science, 2013, doi:10.1371/journal.pbio.1001643.'
short: B. Vicoso, J. Emerson, Y. Zektser, S. Mahajan, D. Bachtrog, PLoS Biology
11 (2013).
date_created: 2018-12-11T11:55:34Z
date_published: 2013-08-27T00:00:00Z
date_updated: 2021-01-12T06:55:09Z
day: '27'
doi: 10.1371/journal.pbio.1001643
extern: 1
intvolume: ' 11'
issue: '8'
license: https://creativecommons.org/licenses/by/4.0/
month: '08'
publication: PLoS Biology
publication_status: published
publisher: Public Library of Science
publist_id: '4962'
quality_controlled: 0
status: public
title: 'Comparative sex chromosome genomics in snakes: Differentiation evolutionary
strata and lack of global dosage compensation'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
volume: 11
year: '2013'
...