---
OA_place: repository
OA_type: green
_id: '21309'
abstract:
- lang: eng
  text: The polarization of light is a critically under-utilized, rich source of information
    in astronomy. For stars in particular, surface magnetism polarization that can
    be detected and measured with spectro-polarimetry. Many questions about these
    surface fields remain unanswered due to a lack of dedicated instruments capable
    of probing weak and strong surface magnetic fields for the entire mass range of
    stars, from M-dwarfs (and even substellar objects) to massive O-type stars at
    different evolutionary stages and metallicities. These questions range from the
    origin of these fields to their true incidence rate throughout the stellar population
    and the dependence on metallicity. Magnetic fields, although currently often excluded
    from stellar evolution models, play an important role in stellar evolution. Connecting
    the surface fields to internal fields through asteroseismology will instigate
    a new era of understanding stellar evolution and the transport of angular momentum
    and chemical elements throughout stellar interiors, also impacting our understanding
    of star-planet interactions and stellar remnants. Polarimetry is also an under-utilized
    tool to observationally constrain the mode identification of nonradial oscillations,
    which lies at the basis of accurate asteroseismic parameter estimation at percentage-level
    for stellar radii, masses, ages, internal rotation, and magnetic field strengths.
    Combining strong constraints on mode identification and surface magnetic properties
    through the acquisition of time-resolved, high-resolution and high-signal-to-noise
    (S/N) spectro-polarimetry and spectroscopy promises to bring leaps forward in
    our understanding of stellar structure, particularly when combined with long-term
    space photometric data from past, current, and future missions.
article_number: '2512.15170'
article_processing_charge: No
arxiv: 1
author:
- first_name: J.
  full_name: Vandersnickt, J.
  last_name: Vandersnickt
- first_name: R. Ochoa
  full_name: Armenta, R. Ochoa
  last_name: Armenta
- first_name: V.
  full_name: Vanlaer, V.
  last_name: Vanlaer
- first_name: A. David-Uraz
  full_name: A. David-Uraz, A. David-Uraz
  last_name: A. David-Uraz
- first_name: C.
  full_name: Aerts, C.
  last_name: Aerts
- first_name: S. B.
  full_name: Das, S. B.
  last_name: Das
- first_name: J. -C.
  full_name: Bouret, J. -C.
  last_name: Bouret
- first_name: D. M.
  full_name: Bowman, D. M.
  last_name: Bowman
- first_name: Lisa Annabelle
  full_name: Bugnet, Lisa Annabelle
  id: d9edb345-f866-11ec-9b37-d119b5234501
  last_name: Bugnet
  orcid: 0000-0003-0142-4000
- first_name: V.
  full_name: Khalack, V.
  last_name: Khalack
- first_name: J. Labadie-Bartz
  full_name: J. Labadie-Bartz, J. Labadie-Bartz
  last_name: J. Labadie-Bartz
- first_name: S.
  full_name: Mathis, S.
  last_name: Mathis
- first_name: Y.
  full_name: Nazé, Y.
  last_name: Nazé
- first_name: C.
  full_name: Neiner, C.
  last_name: Neiner
- first_name: P.
  full_name: Petit, P.
  last_name: Petit
- first_name: V.
  full_name: Petit, V.
  last_name: Petit
- first_name: K. Thomson-Paressant
  full_name: K. Thomson-Paressant, K. Thomson-Paressant
  last_name: K. Thomson-Paressant
- first_name: T. Van
  full_name: Doorsselaere, T. Van
  last_name: Doorsselaere
- first_name: M.
  full_name: Vanrespaille, M.
  last_name: Vanrespaille
citation:
  ama: Vandersnickt J, Armenta RO, Vanlaer V, et al. Expanding stellar horizons with
    polarized light. <i>arXiv</i>. doi:<a href="https://doi.org/10.48550/arXiv.2512.15170">10.48550/arXiv.2512.15170</a>
  apa: Vandersnickt, J., Armenta, R. O., Vanlaer, V., A. David-Uraz, A. D.-U., Aerts,
    C., Das, S. B., … Vanrespaille, M. (n.d.). Expanding stellar horizons with polarized
    light. <i>arXiv</i>. <a href="https://doi.org/10.48550/arXiv.2512.15170">https://doi.org/10.48550/arXiv.2512.15170</a>
  chicago: Vandersnickt, J., R. Ochoa Armenta, V. Vanlaer, A. David-Uraz A. David-Uraz,
    C. Aerts, S. B. Das, J. -C. Bouret, et al. “Expanding Stellar Horizons with Polarized
    Light.” <i>ArXiv</i>, n.d. <a href="https://doi.org/10.48550/arXiv.2512.15170">https://doi.org/10.48550/arXiv.2512.15170</a>.
  ieee: J. Vandersnickt <i>et al.</i>, “Expanding stellar horizons with polarized
    light,” <i>arXiv</i>. .
  ista: Vandersnickt J, Armenta RO, Vanlaer V, A. David-Uraz AD-U, Aerts C, Das SB,
    Bouret J-C, Bowman DM, Bugnet LA, Khalack V, J. Labadie-Bartz JL-B, Mathis S,
    Nazé Y, Neiner C, Petit P, Petit V, K. Thomson-Paressant KT-P, Doorsselaere TV,
    Vanrespaille M. Expanding stellar horizons with polarized light. arXiv, 2512.15170.
  mla: Vandersnickt, J., et al. “Expanding Stellar Horizons with Polarized Light.”
    <i>ArXiv</i>, 2512.15170, doi:<a href="https://doi.org/10.48550/arXiv.2512.15170">10.48550/arXiv.2512.15170</a>.
  short: J. Vandersnickt, R.O. Armenta, V. Vanlaer, A.D.-U. A. David-Uraz, C. Aerts,
    S.B. Das, J.-C. Bouret, D.M. Bowman, L.A. Bugnet, V. Khalack, J.L.-B. J. Labadie-Bartz,
    S. Mathis, Y. Nazé, C. Neiner, P. Petit, V. Petit, K.T.-P. K. Thomson-Paressant,
    T.V. Doorsselaere, M. Vanrespaille, ArXiv (n.d.).
date_created: 2026-02-17T13:53:50Z
date_published: 2025-12-17T00:00:00Z
date_updated: 2026-04-07T06:00:40Z
day: '17'
department:
- _id: LiBu
doi: 10.48550/arXiv.2512.15170
external_id:
  arxiv:
  - '2512.15170'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2512.15170
month: '12'
oa: 1
oa_version: Preprint
publication: arXiv
publication_status: submitted
status: public
title: Expanding stellar horizons with polarized light
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '20864'
abstract:
- lang: eng
  text: Studies of the distant Universe are providing key insights into our understanding
    of the formation of galaxies. The advent of the James Webb Space Telescope (JWST)
    has significantly enhanced our observational capabilities, leading to an expanded
    redshift frontier, providing unprecedented detail in the characterisation of early
    galaxies and enabling the discovery of new populations of accreting black holes.
    This review aims to provide an introduction to the basic processes and components
    that shape the observed spectra of galaxies, with a focus on their relevance to
    techniques with which high-redshift galaxies are selected. The review further
    introduces specific topics that have attracted significant attention in recent
    literature, including the discovery of highly efficient galaxy formation in the
    early Universe, the relation between galaxies and the process of reionization,
    new insights into the formation of the first stars and the enrichment of interstellar
    gas with heavy elements, and breakthroughs in our understanding of the origins
    of supermassive black holes.
acknowledgement: I thank Claudia Di Cesare, Edoardo Iani, Gauri Kotiwale and Wendy
  Sun for proofreading, Daichi Kashino, Gauri Kotiwale, Sara Mascia, Benjamín Navarette
  and Joris Witstok for their assistance in preparing some of the Figures, and Richard
  Ellis and Stephen Blundell for constructive comments. Funded by the European Union
  (ERC, AGENTS, 101076224).
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Jorryt J
  full_name: Matthee, Jorryt J
  id: 7439a258-f3c0-11ec-9501-9df22fe06720
  last_name: Matthee
  orcid: 0000-0003-2871-127X
citation:
  ama: 'Matthee JJ. JWST provides a new view of cosmic dawn: Latest developments in
    studies of early galaxies. <i>Contemporary Physics</i>. 2025;66(1-4):116-151.
    doi:<a href="https://doi.org/10.1080/00107514.2025.2586370">10.1080/00107514.2025.2586370</a>'
  apa: 'Matthee, J. J. (2025). JWST provides a new view of cosmic dawn: Latest developments
    in studies of early galaxies. <i>Contemporary Physics</i>. Taylor &#38; Francis.
    <a href="https://doi.org/10.1080/00107514.2025.2586370">https://doi.org/10.1080/00107514.2025.2586370</a>'
  chicago: 'Matthee, Jorryt J. “JWST Provides a New View of Cosmic Dawn: Latest Developments
    in Studies of Early Galaxies.” <i>Contemporary Physics</i>. Taylor &#38; Francis,
    2025. <a href="https://doi.org/10.1080/00107514.2025.2586370">https://doi.org/10.1080/00107514.2025.2586370</a>.'
  ieee: 'J. J. Matthee, “JWST provides a new view of cosmic dawn: Latest developments
    in studies of early galaxies,” <i>Contemporary Physics</i>, vol. 66, no. 1–4.
    Taylor &#38; Francis, pp. 116–151, 2025.'
  ista: 'Matthee JJ. 2025. JWST provides a new view of cosmic dawn: Latest developments
    in studies of early galaxies. Contemporary Physics. 66(1–4), 116–151.'
  mla: 'Matthee, Jorryt J. “JWST Provides a New View of Cosmic Dawn: Latest Developments
    in Studies of Early Galaxies.” <i>Contemporary Physics</i>, vol. 66, no. 1–4,
    Taylor &#38; Francis, 2025, pp. 116–51, doi:<a href="https://doi.org/10.1080/00107514.2025.2586370">10.1080/00107514.2025.2586370</a>.'
  short: J.J. Matthee, Contemporary Physics 66 (2025) 116–151.
corr_author: '1'
date_created: 2025-12-29T12:05:25Z
date_published: 2025-12-04T00:00:00Z
date_updated: 2026-04-07T08:44:00Z
day: '04'
department:
- _id: JoMa
doi: 10.1080/00107514.2025.2586370
external_id:
  arxiv:
  - '2511.04843'
intvolume: '        66'
issue: 1-4
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2511.04843
month: '12'
oa: 1
oa_version: Preprint
page: 116-151
project:
- _id: bd9b2118-d553-11ed-ba76-db24564edfea
  grant_number: '101076224'
  name: Young galaxies as tracers and agents of cosmic reionization
publication: Contemporary Physics
publication_identifier:
  eissn:
  - 1366-5812
  issn:
  - 0010-7514
publication_status: published
publisher: Taylor & Francis
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'JWST provides a new view of cosmic dawn: Latest developments in studies of
  early galaxies'
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 66
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '21322'
abstract:
- lang: eng
  text: Habitat fragmentation poses a significant risk to population survival, causing
    both demographic stochasticity and genetic drift within local populations to increase,
    thereby increasing genetic load. Higher load causes population numbers to decline,
    which reduces the efficiency of selection and further increases load, resulting
    in a positive feedback that may drive entire populations to extinction. Here,
    we investigate this eco-evolutionary feedback in a metapopulation consisting of
    local demes connected via migration, with individuals subject to deleterious mutation
    at a large number of loci. We first analyze the determinants of load under soft
    selection, where population sizes are fixed, and then build on this to understand
    hard selection, where population sizes and load coevolve. We show that under soft
    selection, very little gene flow (less than one migrant per generation) is enough
    to prevent fixation of deleterious alleles. By contrast, much higher levels of
    migration are required to mitigate load and prevent extinction when selection
    is hard, with critical migration thresholds for metapopulation persistence increasing
    sharply as the genome-wide deleterious mutation rate becomes comparable to the
    baseline population growth rate. Moreover, critical migration thresholds are highest
    if deleterious mutations have intermediate selection coefficients but lower if
    alleles are predominantly recessive rather than additive (due to more efficient
    purging of recessive load within local populations). Our analysis is based on
    a combination of analytical approximations and simulations, allowing for a more
    comprehensive understanding of the factors influencing load and extinction in
    fragmented populations.
acknowledgement: 'This research was partially funded by the Austrian Science Fund
  (FWF P-32896B) and DOC Fellowships of the Austrian Academy of Sciences: grants 26380
  (O.O.) and 26293 (K.K.). We thank Nick Barton for useful comments on the chapter
  in O.O.’s thesis that led to this article.'
article_processing_charge: No
article_type: original
author:
- first_name: Oluwafunmilola O
  full_name: Olusanya, Oluwafunmilola O
  id: 41AD96DC-F248-11E8-B48F-1D18A9856A87
  last_name: Olusanya
  orcid: 0000-0003-1971-8314
- first_name: Kseniia
  full_name: Khudiakova, Kseniia
  id: 4E6DC800-AE37-11E9-AC72-31CAE5697425
  last_name: Khudiakova
  orcid: 0000-0002-6246-1465
- first_name: Himani
  full_name: Sachdeva, Himani
  id: 42377A0A-F248-11E8-B48F-1D18A9856A87
  last_name: Sachdeva
citation:
  ama: Olusanya OO, Khudiakova K, Sachdeva H. Genetic load, eco-evolutionary feedback,
    and extinction in metapopulations. <i>The American Naturalist</i>. 2025;205(6):617-636.
    doi:<a href="https://doi.org/10.1086/735562">10.1086/735562</a>
  apa: Olusanya, O. O., Khudiakova, K., &#38; Sachdeva, H. (2025). Genetic load, eco-evolutionary
    feedback, and extinction in metapopulations. <i>The American Naturalist</i>. University
    of Chicago Press. <a href="https://doi.org/10.1086/735562">https://doi.org/10.1086/735562</a>
  chicago: Olusanya, Oluwafunmilola O, Kseniia Khudiakova, and Himani Sachdeva. “Genetic
    Load, Eco-Evolutionary Feedback, and Extinction in Metapopulations.” <i>The American
    Naturalist</i>. University of Chicago Press, 2025. <a href="https://doi.org/10.1086/735562">https://doi.org/10.1086/735562</a>.
  ieee: O. O. Olusanya, K. Khudiakova, and H. Sachdeva, “Genetic load, eco-evolutionary
    feedback, and extinction in metapopulations,” <i>The American Naturalist</i>,
    vol. 205, no. 6. University of Chicago Press, pp. 617–636, 2025.
  ista: Olusanya OO, Khudiakova K, Sachdeva H. 2025. Genetic load, eco-evolutionary
    feedback, and extinction in metapopulations. The American Naturalist. 205(6),
    617–636.
  mla: Olusanya, Oluwafunmilola O., et al. “Genetic Load, Eco-Evolutionary Feedback,
    and Extinction in Metapopulations.” <i>The American Naturalist</i>, vol. 205,
    no. 6, University of Chicago Press, 2025, pp. 617–36, doi:<a href="https://doi.org/10.1086/735562">10.1086/735562</a>.
  short: O.O. Olusanya, K. Khudiakova, H. Sachdeva, The American Naturalist 205 (2025)
    617–636.
corr_author: '1'
date_created: 2026-02-18T10:47:18Z
date_published: 2025-06-01T00:00:00Z
date_updated: 2026-04-07T08:45:14Z
day: '01'
department:
- _id: JaMa
- _id: NiBa
doi: 10.1086/735562
external_id:
  pmid:
  - '40446297 '
intvolume: '       205'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/2023.12.02.569702
month: '06'
oa: 1
oa_version: Preprint
page: 617-636
pmid: 1
project:
- _id: c08d3278-5a5b-11eb-8a69-fdb09b55f4b8
  grant_number: P32896
  name: Causes and consequences of population fragmentation
- _id: 34c872fe-11ca-11ed-8bc3-8534b82131e6
  grant_number: '26380'
  name: Polygenic Adaptation in a Metapopulation
- _id: 34d33d68-11ca-11ed-8bc3-ec13763c0ca8
  grant_number: '26293'
  name: The impact of deleterious mutations on small populations
publication: The American Naturalist
publication_identifier:
  eissn:
  - 1537-5323
  issn:
  - 0003-0147
publication_status: published
publisher: University of Chicago Press
quality_controlled: '1'
related_material:
  record:
  - id: '14732'
    relation: earlier_version
    status: public
scopus_import: '1'
status: public
title: Genetic load, eco-evolutionary feedback, and extinction in metapopulations
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 205
year: '2025'
...
---
OA_place: repository
OA_type: gold
_id: '21668'
abstract:
- lang: eng
  text: "This artifact allows to review and reproduce the experiments from the paper
    *A Revised Practitioner's Guide to MDP Model Checking Algorithms*.\r\nThe package
    contains all original logfiles and derived data used to generate the plots as
    in the paper. Furthermore, the artifact contains the model checking tools `Storm`
    and `mcsta` in the version exercised in the paper, the used Docker container,
    as well as benchmark instances and execution scripts to reproduce the experiments.\r\n\r\nSee
    also the artifact of the conference paper: https://zenodo.org/records/7509474"
article_processing_charge: No
author:
- first_name: Arnd
  full_name: Hartmanns, Arnd
  last_name: Hartmanns
- first_name: Sebastian
  full_name: Junges, Sebastian
  last_name: Junges
- first_name: Tim
  full_name: Quatmann, Tim
  last_name: Quatmann
- first_name: Maximilian
  full_name: Weininger, Maximilian
  id: 02ab0197-cc70-11ed-ab61-918e71f56881
  last_name: Weininger
  orcid: 0000-0002-0163-2152
citation:
  ama: Hartmanns A, Junges S, Quatmann T, Weininger M. Benchmark data for the revised
    practitioner’s guide to MDP model checking algorithms. 2025. doi:<a href="https://doi.org/10.5281/ZENODO.14500423">10.5281/ZENODO.14500423</a>
  apa: Hartmanns, A., Junges, S., Quatmann, T., &#38; Weininger, M. (2025). Benchmark
    data for the revised practitioner’s guide to MDP model checking algorithms. Zenodo.
    <a href="https://doi.org/10.5281/ZENODO.14500423">https://doi.org/10.5281/ZENODO.14500423</a>
  chicago: Hartmanns, Arnd, Sebastian Junges, Tim Quatmann, and Maximilian Weininger.
    “Benchmark Data for the Revised Practitioner’s Guide to MDP Model Checking Algorithms.”
    Zenodo, 2025. <a href="https://doi.org/10.5281/ZENODO.14500423">https://doi.org/10.5281/ZENODO.14500423</a>.
  ieee: A. Hartmanns, S. Junges, T. Quatmann, and M. Weininger, “Benchmark data for
    the revised practitioner’s guide to MDP model checking algorithms.” Zenodo, 2025.
  ista: Hartmanns A, Junges S, Quatmann T, Weininger M. 2025. Benchmark data for the
    revised practitioner’s guide to MDP model checking algorithms, Zenodo, <a href="https://doi.org/10.5281/ZENODO.14500423">10.5281/ZENODO.14500423</a>.
  mla: Hartmanns, Arnd, et al. <i>Benchmark Data for the Revised Practitioner’s Guide
    to MDP Model Checking Algorithms</i>. Zenodo, 2025, doi:<a href="https://doi.org/10.5281/ZENODO.14500423">10.5281/ZENODO.14500423</a>.
  short: A. Hartmanns, S. Junges, T. Quatmann, M. Weininger, (2025).
date_created: 2026-04-07T09:47:22Z
date_published: 2025-03-07T00:00:00Z
date_updated: 2026-04-07T09:52:55Z
day: '07'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.5281/ZENODO.14500423
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5281/ZENODO.14500423
month: '03'
oa: 1
oa_version: Published Version
publisher: Zenodo
related_material:
  record:
  - id: '21661'
    relation: used_for_analysis_in
    status: public
status: public
title: Benchmark data for the revised practitioner's guide to MDP model checking algorithms
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: repository
_id: '20982'
abstract:
- lang: eng
  text: Plant cells respond to a wide range of stimuli through intracellular calcium
    (Ca2+) signaling. Cyclic nucleotide-gated channels (CNGCs) are a major class of
    plant Ca2+ channels, with 20 homologs in Arabidopsis. These tetrameric plasma
    membrane proteins act downstream of diverse signals, such as phytohormones, extracellular
    damage, cell wall integrity or temperature. Here, we identify a class of plant-specific
    proteins, Armadillo Repeat Only (ARO), as essential regulators of possibly all
    plant CNGCs. Abrogation of functional sporophytic AROs results in a phenotypic
    pattern strongly reminiscent of CNGC dysfunction, including defects in root gravitropism,
    root hair growth and morphology, stomatal movement, and responses to extracellular
    ATP and the phytohormone auxin. aro2/3/4 mutants are fully resistant to the toxic
    effects caused by overexpression of CNGCs. AROs colocalize and physically interact
    with multiple CNGCs and modulate CNGC-dependent currents in Xenopus oocytes. Structural
    modeling and site-directed mutagenesis reveal AROs tetramer formation surrounding
    the CNGC channel, interacting via its IQ domain. Taken together, plant CNGC channels
    don’t act alone, but in a larger complex - channelosome, first of a kind in plants.
acknowledgement: "This project was supported by the Czech Science Foundation grant
  Nr. 25-16449S and by European\r\nUnion, Horizon Europe, project MOLIPEC, ID 101087030.
  Computational resources used for structural\r\nmodeling were provided by the e-INFRA
  CZ project (ID:90254), supported by the Ministry of Education,\r\nYouth and Sports
  of the Czech Republic. Part of the work was carried out with the support of a Growth\r\nFacility
  (BC Core Facilities; IPMB BC CAS). X. laevis oocytes were kindly provided by C.
  Korbmacher on\r\na regular basis (FAU Erlangen-Nürnberg). MF received support from
  the European Research Council\r\n(Grant 480 No. 101125499). We acknowledge the core
  facility LMH, the BC CAS supported by the MEYS\r\nCR (LM 2023050 Czech-BioImaging).
  DO received support from the Czech Science Foundation grant Nr.\r\n24-12107S\r\n"
article_processing_charge: No
author:
- first_name: Ivan
  full_name: Kulich, Ivan
  id: 57a1567c-8314-11eb-9063-c9ddc3451a54
  last_name: Kulich
- first_name: Denisa
  full_name: Oulehlová, Denisa
  last_name: Oulehlová
- first_name: Dmitrii
  full_name: Vladimirtsev, Dmitrii
  id: 60466724-5355-11ee-ae5a-fa55e8f99c3d
  last_name: Vladimirtsev
- first_name: Minxia
  full_name: Zou, Minxia
  id: 5c243f41-03f3-11ec-841c-96faf48a7ef9
  last_name: Zou
- first_name: Edita
  full_name: Lileikyte, Edita
  last_name: Lileikyte
- first_name: Alexey
  full_name: Bondar, Alexey
  last_name: Bondar
- first_name: Katarína
  full_name: Kulichová, Katarína
  last_name: Kulichová
- first_name: Martin
  full_name: Janda, Martin
  last_name: Janda
- first_name: Oksana
  full_name: Iakovenko, Oksana
  last_name: Iakovenko
- first_name: Michaela
  full_name: Neubergerová, Michaela
  last_name: Neubergerová
- first_name: Tanja
  full_name: Studtrucker, Tanja
  last_name: Studtrucker
- first_name: Roman
  full_name: Pleskot, Roman
  last_name: Pleskot
- first_name: Petra
  full_name: Dietrich, Petra
  last_name: Dietrich
- first_name: Matyas
  full_name: Fendrych, Matyas
  id: 43905548-F248-11E8-B48F-1D18A9856A87
  last_name: Fendrych
  orcid: 0000-0002-9767-8699
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Kulich I, Oulehlová D, Vladimirtsev D, et al. Armadillo repeat only proteins
    are required for the function of plant CNGC channels. <i>bioRxiv</i>. doi:<a href="https://doi.org/10.1101/2025.01.06.631460">10.1101/2025.01.06.631460</a>
  apa: Kulich, I., Oulehlová, D., Vladimirtsev, D., Zou, M., Lileikyte, E., Bondar,
    A., … Friml, J. (n.d.). Armadillo repeat only proteins are required for the function
    of plant CNGC channels. <i>bioRxiv</i>. <a href="https://doi.org/10.1101/2025.01.06.631460">https://doi.org/10.1101/2025.01.06.631460</a>
  chicago: Kulich, Ivan, Denisa Oulehlová, Dmitrii Vladimirtsev, Minxia Zou, Edita
    Lileikyte, Alexey Bondar, Katarína Kulichová, et al. “Armadillo Repeat Only Proteins
    Are Required for the Function of Plant CNGC Channels.” <i>BioRxiv</i>, n.d. <a
    href="https://doi.org/10.1101/2025.01.06.631460">https://doi.org/10.1101/2025.01.06.631460</a>.
  ieee: I. Kulich <i>et al.</i>, “Armadillo repeat only proteins are required for
    the function of plant CNGC channels,” <i>bioRxiv</i>. .
  ista: Kulich I, Oulehlová D, Vladimirtsev D, Zou M, Lileikyte E, Bondar A, Kulichová
    K, Janda M, Iakovenko O, Neubergerová M, Studtrucker T, Pleskot R, Dietrich P,
    Fendrych M, Friml J. Armadillo repeat only proteins are required for the function
    of plant CNGC channels. bioRxiv, <a href="https://doi.org/10.1101/2025.01.06.631460">10.1101/2025.01.06.631460</a>.
  mla: Kulich, Ivan, et al. “Armadillo Repeat Only Proteins Are Required for the Function
    of Plant CNGC Channels.” <i>BioRxiv</i>, doi:<a href="https://doi.org/10.1101/2025.01.06.631460">10.1101/2025.01.06.631460</a>.
  short: I. Kulich, D. Oulehlová, D. Vladimirtsev, M. Zou, E. Lileikyte, A. Bondar,
    K. Kulichová, M. Janda, O. Iakovenko, M. Neubergerová, T. Studtrucker, R. Pleskot,
    P. Dietrich, M. Fendrych, J. Friml, BioRxiv (n.d.).
corr_author: '1'
date_created: 2026-01-13T14:07:58Z
date_published: 2025-05-16T00:00:00Z
date_updated: 2026-04-07T11:41:43Z
day: '16'
department:
- _id: JiFr
doi: 10.1101/2025.01.06.631460
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/2025.01.06.631460
month: '05'
oa: 1
oa_version: Preprint
publication: bioRxiv
publication_status: draft
related_material:
  record:
  - id: '20964'
    relation: dissertation_contains
    status: public
status: public
title: Armadillo repeat only proteins are required for the function of plant CNGC
  channels
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: preprint
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20260'
abstract:
- lang: eng
  text: The medial axis of a set consists of the points in the ambient space without
    a unique closest point in the original set. Since its introduction, the medial
    axis has been used extensively in many applications as a method of computing a
    skeleton topologically equivalent to the original set. Unfortunately, one limiting
    factor in the use of the medial axis of a smooth manifold is that it is not necessarily
    topologically stable under small perturbations of the manifold. To counter these
    instabilities, various prunings of the medial axis have been proposed in the computational
    geometry community. Here, we examine one type of pruning, called burning. Because
    of the good experimental results it was hoped that the burning method of simplifying
    the medial axis would be stable. In this work, we show a simple example that dashes
    such hopes. Based on Bing’s house with two rooms, we demonstrate an isotopy of
    a shape where the medial axis goes from collapsible to non-collapsible. More precisely,
    we consider the standard deformation retract from the closed ball to Bing’s house
    with two rooms, but stop just short of the point where Bing’s house becomes two
    dimensional. This way we obtain an isotopy from the 3-ball to a thickened version
    of Bing’s house. Under this isotopy, the medial axis goes from collapsible to
    non-collapsible. We stress that this isotopy can be made generic, in the sense
    of singularity theory, as developed by Arnol’d and Thom.
acknowledgement: "We thank André Lieutier, David Letscher, Ellen Gasparovic, Kathryn
  Leonard, and Tao Ju for early discussions on this work. We also thank Lu Liu, Yajie
  Yan, and Tao Ju for sharing code to generate the examples. We further thank Abigail
  Thompson for discussion on the conjecture and James Damon for sharing his insight
  in singularity theory. We thank the reviewers for their detailed reviews, which
  helped to improve the exposition.\r\nOpen access funding provided by Institute of
  Science and Technology (IST Austria). Partially supported by the DFG Collaborative
  Research Center TRR 109, ‘Discretization in Geometry and Dynamics’ and the European
  Research Council (ERC), grant no. 788183, ‘Alpha Shape Theory Extended’. The first
  author was supported in part by the National Science Foundation through grants DBI-1759807,
  CCF-1907612, and CCF-2444309. The fourth author was supported by the European Union’s
  Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie
  grant agreement No. 754411, the Austrian science fund (FWF) M-3073, ANR grant StratMesh,
  ANR-24-CE48-1899, and the welcome package from IDEX of the Université Côte d’Azur,
  ANR-15-IDEX-01."
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Erin Wolf
  full_name: Chambers, Erin Wolf
  last_name: Chambers
- first_name: Christopher D
  full_name: Fillmore, Christopher D
  id: 35638A5C-AAC7-11E9-B0BF-5503E6697425
  last_name: Fillmore
- first_name: Elizabeth R
  full_name: Stephenson, Elizabeth R
  id: 2D04F932-F248-11E8-B48F-1D18A9856A87
  last_name: Stephenson
  orcid: 0000-0002-6862-208X
- first_name: Mathijs
  full_name: Wintraecken, Mathijs
  id: 307CFBC8-F248-11E8-B48F-1D18A9856A87
  last_name: Wintraecken
  orcid: 0000-0002-7472-2220
citation:
  ama: Chambers EW, Fillmore CD, Stephenson ER, Wintraecken M. Burning or collapsing
    the medial axis is unstable. <i>La Matematica</i>. 2025;4:811-828. doi:<a href="https://doi.org/10.1007/s44007-025-00170-0">10.1007/s44007-025-00170-0</a>
  apa: Chambers, E. W., Fillmore, C. D., Stephenson, E. R., &#38; Wintraecken, M.
    (2025). Burning or collapsing the medial axis is unstable. <i>La Matematica</i>.
    Springer Nature. <a href="https://doi.org/10.1007/s44007-025-00170-0">https://doi.org/10.1007/s44007-025-00170-0</a>
  chicago: Chambers, Erin Wolf, Christopher D Fillmore, Elizabeth R Stephenson, and
    Mathijs Wintraecken. “Burning or Collapsing the Medial Axis Is Unstable.” <i>La
    Matematica</i>. Springer Nature, 2025. <a href="https://doi.org/10.1007/s44007-025-00170-0">https://doi.org/10.1007/s44007-025-00170-0</a>.
  ieee: E. W. Chambers, C. D. Fillmore, E. R. Stephenson, and M. Wintraecken, “Burning
    or collapsing the medial axis is unstable,” <i>La Matematica</i>, vol. 4. Springer
    Nature, pp. 811–828, 2025.
  ista: Chambers EW, Fillmore CD, Stephenson ER, Wintraecken M. 2025. Burning or collapsing
    the medial axis is unstable. La Matematica. 4, 811–828.
  mla: Chambers, Erin Wolf, et al. “Burning or Collapsing the Medial Axis Is Unstable.”
    <i>La Matematica</i>, vol. 4, Springer Nature, 2025, pp. 811–28, doi:<a href="https://doi.org/10.1007/s44007-025-00170-0">10.1007/s44007-025-00170-0</a>.
  short: E.W. Chambers, C.D. Fillmore, E.R. Stephenson, M. Wintraecken, La Matematica
    4 (2025) 811–828.
corr_author: '1'
date_created: 2025-08-31T22:01:33Z
date_published: 2025-12-01T00:00:00Z
date_updated: 2026-04-07T11:42:48Z
day: '01'
ddc:
- '510'
department:
- _id: HeEd
doi: 10.1007/s44007-025-00170-0
ec_funded: 1
file:
- access_level: open_access
  checksum: e2043259194bfcdf3d74c4da8a5a853f
  content_type: application/pdf
  creator: dernst
  date_created: 2025-12-30T07:52:58Z
  date_updated: 2025-12-30T07:52:58Z
  file_id: '20885'
  file_name: 2025_LaMatematica_Chambers.pdf
  file_size: 2678640
  relation: main_file
  success: 1
file_date_updated: 2025-12-30T07:52:58Z
has_accepted_license: '1'
intvolume: '         4'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 811-828
project:
- _id: 266A2E9E-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '788183'
  name: Alpha Shape Theory Extended
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
- _id: fc390959-9c52-11eb-aca3-afa58bd282b2
  grant_number: M03073
  name: Learning and triangulating manifolds via collapses
publication: La Matematica
publication_identifier:
  eissn:
  - 2730-9657
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  record:
  - id: '21021'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Burning or collapsing the medial axis is unstable
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 4
year: '2025'
...
---
OA_place: publisher
OA_type: gold
_id: '20819'
abstract:
- lang: eng
  text: "Clustering is a cornerstone of data analysis that is particularly suited
    to identifying coherent subgroups or substructures in unlabeled data, as are generated
    continuously in large amounts these days. However, in many cases traditional clustering
    methods are not applicable, because data are increasingly being produced and stored
    in a distributed way, e.g. on edge devices, and privacy concerns prevent it from
    being transferred to a central server. To address this challenge, we present FedDP-KMeans,
    a new algorithm for \r\n-means clustering that is fully-federated as well as differentially
    private. Our approach leverages (potentially small and out-of-distribution) server-side
    data to overcome the primary challenge of differentially private clustering methods:
    the need for a good initialization. Combining our initialization with a simple
    federated DP-Lloyds algorithm we obtain an algorithm that achieves excellent results
    on synthetic and real-world benchmark tasks. We also provide a theoretical analysis
    of our method that provides bounds on the convergence speed and cluster identification
    success."
acknowledged_ssus:
- _id: ScienComp
acknowledgement: "This research was funded in part by the Austrian Science Fund (FWF)
  [10.55776/COE12] and supported by the Scientific Service Units (SSU) of ISTA through
  resources provided by Scientific Computing (SciComp).\r\n"
alternative_title:
- PMLR
article_processing_charge: No
arxiv: 1
author:
- first_name: Jonathan A
  full_name: Scott, Jonathan A
  id: e499926b-f6e0-11ea-865d-9c63db0031e8
  last_name: Scott
- first_name: Christoph
  full_name: Lampert, Christoph
  id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
  last_name: Lampert
  orcid: 0000-0001-8622-7887
- first_name: David
  full_name: Saulpic, David
  id: f8e48cf0-b0ff-11ed-b0e9-b4c35598f964
  last_name: Saulpic
citation:
  ama: 'Scott JA, Lampert C, Saulpic D. Differentially private federated k-means clustering
    with server-side data. In: <i>42nd International Conference on Machine Learning</i>.
    Vol 267. ML Research Press; 2025:53757-53790.'
  apa: 'Scott, J. A., Lampert, C., &#38; Saulpic, D. (2025). Differentially private
    federated k-means clustering with server-side data. In <i>42nd International Conference
    on Machine Learning</i> (Vol. 267, pp. 53757–53790). Vancouver, Canada: ML Research
    Press.'
  chicago: Scott, Jonathan A, Christoph Lampert, and David Saulpic. “Differentially
    Private Federated K-Means Clustering with Server-Side Data.” In <i>42nd International
    Conference on Machine Learning</i>, 267:53757–90. ML Research Press, 2025.
  ieee: J. A. Scott, C. Lampert, and D. Saulpic, “Differentially private federated
    k-means clustering with server-side data,” in <i>42nd International Conference
    on Machine Learning</i>, Vancouver, Canada, 2025, vol. 267, pp. 53757–53790.
  ista: 'Scott JA, Lampert C, Saulpic D. 2025. Differentially private federated k-means
    clustering with server-side data. 42nd International Conference on Machine Learning.
    ICML: International Conference on Machine Learning, PMLR, vol. 267, 53757–53790.'
  mla: Scott, Jonathan A., et al. “Differentially Private Federated K-Means Clustering
    with Server-Side Data.” <i>42nd International Conference on Machine Learning</i>,
    vol. 267, ML Research Press, 2025, pp. 53757–90.
  short: J.A. Scott, C. Lampert, D. Saulpic, in:, 42nd International Conference on
    Machine Learning, ML Research Press, 2025, pp. 53757–53790.
conference:
  end_date: 2025-07-19
  location: Vancouver, Canada
  name: 'ICML: International Conference on Machine Learning'
  start_date: 2025-07-13
corr_author: '1'
date_created: 2025-12-14T23:02:05Z
date_published: 2025-05-01T00:00:00Z
date_updated: 2026-04-07T11:46:11Z
day: '01'
ddc:
- '000'
department:
- _id: ChLa
- _id: MoHe
external_id:
  arxiv:
  - '2506.05408'
file:
- access_level: open_access
  checksum: 815b32b463023ca21e569c2158745c15
  content_type: application/pdf
  creator: dernst
  date_created: 2025-12-16T12:38:29Z
  date_updated: 2025-12-16T12:38:29Z
  file_id: '20829'
  file_name: 2025_ICML_Scott.pdf
  file_size: 746612
  relation: main_file
  success: 1
file_date_updated: 2025-12-16T12:38:29Z
has_accepted_license: '1'
intvolume: '       267'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: 53757-53790
publication: 42nd International Conference on Machine Learning
publication_identifier:
  eissn:
  - 2640-3498
publication_status: published
publisher: ML Research Press
quality_controlled: '1'
related_material:
  record:
  - id: '21198'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Differentially private federated k-means clustering with server-side data
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 267
year: '2025'
...
---
OA_place: repository
_id: '21207'
abstract:
- lang: eng
  text: Personalized federated learning has emerged as a popular approach to training
    on devices holding statistically heterogeneous data, known as clients. However,
    most existing approaches require a client to have labeled data for training or
    finetuning in order to obtain their own personalized model. In this paper we address
    this by proposing FLowDUP, a novel method that is able to generate a personalized
    model using only a forward pass with unlabeled data. The generated model parameters
    reside in a low-dimensional subspace, enabling efficient communication and computation.
    FLowDUP's learning objective is theoretically motivated by our new transductive
    multi-task PAC-Bayesian generalization bound, that provides performance guarantees
    for unlabeled clients. The objective is structured in such a way that it allows
    both clients with labeled data and clients with only unlabeled data to contribute
    to the training process. To supplement our theoretical results we carry out a
    thorough experimental evaluation of FLowDUP, demonstrating strong empirical performance
    on a range of datasets with differing sorts of statistically heterogeneous clients.
    Through numerous ablation studies, we test the efficacy of the individual components
    of the method.
article_processing_charge: No
author:
- first_name: Hossein
  full_name: Zakerinia, Hossein
  id: 653bd8b6-f394-11eb-9cf6-c0bbf6cd78d4
  last_name: Zakerinia
  orcid: 0009-0007-3977-6462
- first_name: Jonathan A
  full_name: Scott, Jonathan A
  id: e499926b-f6e0-11ea-865d-9c63db0031e8
  last_name: Scott
- first_name: Christoph
  full_name: Lampert, Christoph
  id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
  last_name: Lampert
  orcid: 0000-0001-8622-7887
citation:
  ama: 'Zakerinia H, Scott JA, Lampert C. Federated learning with unlabeled clients:
    Personalization can happen in low dimensions. <i>arXiv</i>. doi:<a href="https://doi.org/10.48550/ARXIV.2505.15579">10.48550/ARXIV.2505.15579</a>'
  apa: 'Zakerinia, H., Scott, J. A., &#38; Lampert, C. (n.d.). Federated learning
    with unlabeled clients: Personalization can happen in low dimensions. <i>arXiv</i>.
    <a href="https://doi.org/10.48550/ARXIV.2505.15579">https://doi.org/10.48550/ARXIV.2505.15579</a>'
  chicago: 'Zakerinia, Hossein, Jonathan A Scott, and Christoph Lampert. “Federated
    Learning with Unlabeled Clients: Personalization Can Happen in Low Dimensions.”
    <i>ArXiv</i>, n.d. <a href="https://doi.org/10.48550/ARXIV.2505.15579">https://doi.org/10.48550/ARXIV.2505.15579</a>.'
  ieee: 'H. Zakerinia, J. A. Scott, and C. Lampert, “Federated learning with unlabeled
    clients: Personalization can happen in low dimensions,” <i>arXiv</i>. .'
  ista: 'Zakerinia H, Scott JA, Lampert C. Federated learning with unlabeled clients:
    Personalization can happen in low dimensions. arXiv, <a href="https://doi.org/10.48550/ARXIV.2505.15579">10.48550/ARXIV.2505.15579</a>.'
  mla: 'Zakerinia, Hossein, et al. “Federated Learning with Unlabeled Clients: Personalization
    Can Happen in Low Dimensions.” <i>ArXiv</i>, doi:<a href="https://doi.org/10.48550/ARXIV.2505.15579">10.48550/ARXIV.2505.15579</a>.'
  short: H. Zakerinia, J.A. Scott, C. Lampert, ArXiv (n.d.).
corr_author: '1'
date_created: 2026-02-10T08:20:59Z
date_published: 2025-05-21T00:00:00Z
date_updated: 2026-04-07T11:46:11Z
day: '21'
department:
- _id: ChLa
doi: 10.48550/ARXIV.2505.15579
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2505.15579
month: '05'
oa: 1
oa_version: Preprint
publication: arXiv
publication_status: draft
related_material:
  record:
  - id: '21198'
    relation: dissertation_contains
    status: public
status: public
title: 'Federated learning with unlabeled clients: Personalization can happen in low
  dimensions'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: preprint
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2025'
...
---
OA_place: repository
_id: '21050'
abstract:
- lang: eng
  text: "In 1873, James C. Maxwell conjectured that the electric field generated by
    $n$ point charges in generic position has at most $(n-1)^2$ isolated zeroes. The
    first (non-optimal) upper bound was only obtained in 2007 by Gabrielov, Novikov
    and Shapiro, who also posed two additional interesting conjectures.\r\n In this
    article, we give the best upper bound known to date on the number of zeroes of
    the electric field, and construct a counterexample to a conjecture of Gabrielov,
    Novikov and Shapiro that the number of equilibria cannot exceed those of the distance
    function defined by the unit point charges.\r\n Finally, we note that it is quite
    possible that Maxwell's quadratic upper bound is not tight, so it is prudent to
    find smaller bounds. Hence, we also explore examples and construct configurations
    of charges achieving the highest ratios of the number of electric field zeroes
    by point charges found to this day."
article_processing_charge: No
arxiv: 1
author:
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
- first_name: Christopher D
  full_name: Fillmore, Christopher D
  id: 35638A5C-AAC7-11E9-B0BF-5503E6697425
  last_name: Fillmore
- first_name: Gonçalo
  full_name: Olivera, Gonçalo
  last_name: Olivera
citation:
  ama: Edelsbrunner H, Fillmore CD, Olivera G. Counting equilibria of the electrostatic
    potential. <i>arXiv</i>. doi:<a href="https://doi.org/10.48550/ARXIV.2501.05315">10.48550/ARXIV.2501.05315</a>
  apa: Edelsbrunner, H., Fillmore, C. D., &#38; Olivera, G. (n.d.). Counting equilibria
    of the electrostatic potential. <i>arXiv</i>. <a href="https://doi.org/10.48550/ARXIV.2501.05315">https://doi.org/10.48550/ARXIV.2501.05315</a>
  chicago: Edelsbrunner, Herbert, Christopher D Fillmore, and Gonçalo Olivera. “Counting
    Equilibria of the Electrostatic Potential.” <i>ArXiv</i>, n.d. <a href="https://doi.org/10.48550/ARXIV.2501.05315">https://doi.org/10.48550/ARXIV.2501.05315</a>.
  ieee: H. Edelsbrunner, C. D. Fillmore, and G. Olivera, “Counting equilibria of the
    electrostatic potential,” <i>arXiv</i>. .
  ista: Edelsbrunner H, Fillmore CD, Olivera G. Counting equilibria of the electrostatic
    potential. arXiv, <a href="https://doi.org/10.48550/ARXIV.2501.05315">10.48550/ARXIV.2501.05315</a>.
  mla: Edelsbrunner, Herbert, et al. “Counting Equilibria of the Electrostatic Potential.”
    <i>ArXiv</i>, doi:<a href="https://doi.org/10.48550/ARXIV.2501.05315">10.48550/ARXIV.2501.05315</a>.
  short: H. Edelsbrunner, C.D. Fillmore, G. Olivera, ArXiv (n.d.).
corr_author: '1'
date_created: 2026-01-27T14:29:27Z
date_published: 2025-03-20T00:00:00Z
date_updated: 2026-04-07T11:42:48Z
day: '20'
department:
- _id: HeEd
doi: 10.48550/ARXIV.2501.05315
external_id:
  arxiv:
  - '2501.05315'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2501.05315
month: '03'
oa: 1
oa_version: Preprint
publication: arXiv
publication_status: draft
related_material:
  record:
  - id: '21021'
    relation: dissertation_contains
    status: public
status: public
title: Counting equilibria of the electrostatic potential
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: preprint
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2025'
...
---
OA_place: publisher
_id: '19684'
abstract:
- lang: eng
  text: "The overarching goal of this thesis is to break down the complexity of turbulent
    flows in terms of enumerable, coherent structures and patterns. In a five-paper
    series, we adopt a variety of perspectives and techniques to relate the properties
    of systems of increasing complexity to their underlying coherent structures. \r\n\r\nInitially,
    we take a dynamical systems point of view, seeing turbulent flow as a chaotic
    trajectory bouncing between exact unstable solutions of the underlying equations
    of motion. Using persistent homology, the main tool of topological data analysis
    capturing the persistence across scales of topological features in a point cloud,
    we introduce a method that quantifies visits of turbulent trajectories to unstable
    time-periodic solutions, also called periodic orbits. We demonstrate this method
    first in the Rössler and Kuramoto–Sivashinsky systems. Using this method in 3D
    Kolmogorov flow, we extract a Markov chain from turbulent data, where each node
    corresponds to the neighbourhood of a periodic orbit. The invariant distribution
    of this Markov chain reproduces expectation values on turbulent data when it is
    used to weight averages on the respective periodic orbits.\r\n\r\nIn more realistic,
    wall-bounded settings, such as plane-Couette flow (pcf) driven by the relative
    motion of the walls, or plane-Poiseuille flow (ppf) driven by a pressure gradient,
    finding exact solutions is difficult. We use dynamic mode decomposition (DMD),
    a dimensionality reduction method for sequential data, to identify and approximate
    low-dimensional dynamics without knowing any exact solutions. Most spatially-extended
    systems are equivariant under translations, and in such cases spatial drifts dominate
    DMD, hindering its use in the search for and modelling of low-dimensional dynamics.
    We augment DMD with a symmetry reduction method trained on turbulent data to stop
    it from seeing translations as a feature, improving its ability to extract dynamical
    information in translation-equivariant systems. We find segments of turbulent
    trajectories that linearize well with their symmetry-reduced DMD spectra, akin
    to dynamics near exact solutions. Searching for harmonics in the spectra gives
    leads for periodic orbits with spatial drifts, one of which converges to a new
    solution.\r\n\r\nIn larger domains, turbulence can localize and coexist with surrounding
    laminar flow. Our preceding approaches are global, taking all of a domain into
    account at once, and cannot readily treat each localized patch individually. Working
    first in a minimal oblique domain that can host a single 1D-localized turbulent
    patch, we find that turbulence in ppf is connected to a stable periodic orbit
    at a flow velocity much lower than when turbulence is first onset. We show that,
    well in advance of sustained turbulence, chaos sets in explosively, and for long
    time horizons, time series are consistent with that of a random process.\r\n\r\nFinally,
    in much larger domains, we study and compare 2D-localized turbulence that appears
    as large-scale inclined structures, called stripes, in ppf and pcf. While appearing
    similar, we find that stripes in these two settings differ significantly in terms
    of how they sustain themselves, and in higher velocities, how they proliferate."
acknowledged_ssus:
- _id: ScienComp
acknowledgement: "The work in this thesis was supported by a grant from the Simons
  Foundation (662960, BH).\r\n"
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Gökhan
  full_name: Yalniz, Gökhan
  id: 66E74FA2-D8BF-11E9-8249-8DE2E5697425
  last_name: Yalniz
  orcid: 0000-0002-8490-9312
citation:
  ama: 'Yalniz G. Transition to turbulence : Data-, solution-, and pattern-driven
    approaches. 2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-19684">10.15479/AT-ISTA-19684</a>'
  apa: 'Yalniz, G. (2025). <i>Transition to turbulence : Data-, solution-, and pattern-driven
    approaches</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-19684">https://doi.org/10.15479/AT-ISTA-19684</a>'
  chicago: 'Yalniz, Gökhan. “Transition to Turbulence : Data-, Solution-, and Pattern-Driven
    Approaches.” Institute of Science and Technology Austria, 2025. <a href="https://doi.org/10.15479/AT-ISTA-19684">https://doi.org/10.15479/AT-ISTA-19684</a>.'
  ieee: 'G. Yalniz, “Transition to turbulence : Data-, solution-, and pattern-driven
    approaches,” Institute of Science and Technology Austria, 2025.'
  ista: 'Yalniz G. 2025. Transition to turbulence : Data-, solution-, and pattern-driven
    approaches. Institute of Science and Technology Austria.'
  mla: 'Yalniz, Gökhan. <i>Transition to Turbulence : Data-, Solution-, and Pattern-Driven
    Approaches</i>. Institute of Science and Technology Austria, 2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-19684">10.15479/AT-ISTA-19684</a>.'
  short: 'G. Yalniz, Transition to Turbulence : Data-, Solution-, and Pattern-Driven
    Approaches, Institute of Science and Technology Austria, 2025.'
corr_author: '1'
date_created: 2025-05-12T15:12:28Z
date_published: 2025-05-13T00:00:00Z
date_updated: 2026-04-07T11:47:06Z
day: '13'
ddc:
- '514'
- '519'
- '532'
- '004'
degree_awarded: PhD
department:
- _id: GradSch
- _id: BjHo
doi: 10.15479/AT-ISTA-19684
file:
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  content_type: video/mp4
  creator: gyalniz
  date_created: 2025-05-12T15:15:59Z
  date_updated: 2025-05-12T15:43:28Z
  description: '3D visualizations of the turbulent flow (left) and the periodic orbits
    (middle) that are being shadowed along with the local state space projections
    (right) onto the principal components of the respective periodic orbit. Shown
    here are the isosurfaces of velocity (red/blue: ±95% of the instantaneous maximum)
    and vorticity (purple/green: ±65% of the instantaneous maximum) in the x-direction.
    Markers along the projections are in sync with the 3D visualizations. The movie
    corresponds to the initial time interval (up to t = 100) of figure 2.2 (a,b);
    periodic orbits and the state space projections are shown only through the shadowing
    events indicated in figure 2.2 (b).'
  file_id: '19686'
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  file_size: 37763743
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  title: Chapter 2 - Movie 2A.1
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  content_type: video/mp4
  creator: gyalniz
  date_created: 2025-05-12T15:16:09Z
  date_updated: 2025-05-12T15:43:28Z
  description: 'Turbulent flow (left) in HKW domain and its symmetry reduction (right).
    Shown here are the isosurfaces of streamwise velocity (red/blue: u = 0.5 max/min
    u) and streamwise vorticity (green/purple: ω_x = 0.5 max/min ω_x).'
  file_id: '19687'
  file_name: Movie 3A.1.mp4
  file_size: 3902655
  relation: supplementary_material
  title: Chapter 3 - Movie 3A.1
- access_level: open_access
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  content_type: video/mp4
  creator: gyalniz
  date_created: 2025-05-12T15:16:21Z
  date_updated: 2025-05-12T15:43:28Z
  description: 'Turbulent flow (left) in P2K domain and its symmetry reduction (right).
    Shown here are the isosurfaces of streamwise velocity (red/blue: u = 0.5 max/min
    u) and streamwise vorticity (green/purple: ω_x = 0.5 max/min ω_x).'
  file_id: '19688'
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  title: Chapter 3 - Movie 3A.2
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  content_type: video/mp4
  creator: gyalniz
  date_created: 2025-05-12T15:16:36Z
  date_updated: 2025-05-12T15:43:28Z
  description: 'Relative periodic orbit RPO_79.4 (left) of the plane-Couette flow
    (HKW domain) and its symmetry reduction (right). Shown here are the isosurfaces
    of streamwise velocity (red/blue: u = 0.5 max/min u) and streamwise vorticity
    (green/purple: ω_x = 0.5 max/min ω_x).'
  file_id: '19689'
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  creator: gyalniz
  date_created: 2025-05-12T15:16:50Z
  date_updated: 2025-05-12T15:43:28Z
  description: 'Symmetry-reduced flow (left), its SRDMD approximation (middle), and
    state space projection (right) showing the spiral-out episode in P2K domain (figure
    3.6 (b) and figure 3.8 (b)). Shown here are the isosurfaces of streamwise velocity
    (red/blue: u = 0.5 max/min u) and streamwise vorticity (green/purple: ω_x = 0.5
    max/min ω_x).'
  file_id: '19690'
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  content_type: video/mp4
  creator: gyalniz
  date_created: 2025-05-12T15:17:11Z
  date_updated: 2025-05-12T15:43:28Z
  description: Movie demonstrating the quasi-steady Reynolds number descent from turbulence
    to a periodic orbit.
  file_id: '19691'
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  relation: supplementary_material
  title: Chapter 4 - Movie 4A.1
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  content_type: video/mp4
  creator: gyalniz
  date_created: 2025-05-12T15:17:43Z
  date_updated: 2025-05-12T15:43:28Z
  description: Streamwise velocity fluctuations (from laminar) of plane-Couette flow
    (Re^C =335) at the y = 0 wall-normal plane in coordinates stationary with respect
    to the bulk velocity. Here, x is the streamwise direction (the wall at y = 1 moves
    to the right) and z is the spanwise direction. Time is in advectime time units.
    Shown is the full (L_x = L_z = 400) domain.
  file_id: '19692'
  file_name: Movie 5A.1.mp4
  file_size: 5893993
  relation: supplementary_material
  title: Chapter 5 - Movie 5A.1
- access_level: open_access
  checksum: fd17eabb70129ceaa414e40924d1d2fe
  content_type: video/mp4
  creator: gyalniz
  date_created: 2025-05-12T15:17:49Z
  date_updated: 2025-05-12T15:43:28Z
  description: Streamwise velocity fluctuations (from laminar) of plane-Poiseuille
    flow (Re^P =660) at the y = 0.5 wall-normal plane in coordinates stationary with
    respect to the bulk velocity. Here, x is the streamwise direction (the mean negative
    pressure gradient is to the right) and z is the spanwise direction. Time is in
    advectime time units. Shown is the full (L_x = L_z = 400) domain.
  file_id: '19693'
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  file_size: 3990352
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  title: Chapter 5 - Movie 5A.2
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  content_type: video/mp4
  creator: gyalniz
  date_created: 2025-05-12T15:17:58Z
  date_updated: 2025-05-12T15:43:28Z
  description: Streamwise velocity fluctuations (from laminar) of plane-Poiseuille
    flow (Re^P=660) at the y = 0.5 wall-normal plane in coordinates stationary with
    respect to the average velocity of the downstream tip of the stripe. Here, x is
    the streamwise direction (the mean negative pressure gradient is to the right)
    and z is the spanwise direction. Time is in advectime time units. Shown is a zoom-in
    of the full (L_x = L_z) domain.
  file_id: '19694'
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  title: Chapter 5 - Movie 5A.3
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  creator: gyalniz
  date_created: 2025-05-12T15:27:10Z
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has_accepted_license: '1'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: '155'
project:
- _id: 238598C6-32DE-11EA-91FC-C7463DDC885E
  grant_number: '662960'
  name: Revisiting the Turbulence Problem Using Statistical Mechanics
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '7563'
    relation: part_of_dissertation
    status: public
  - id: '9558'
    relation: part_of_dissertation
    status: public
  - id: '12105'
    relation: part_of_dissertation
    status: public
  - id: '13274'
    relation: part_of_dissertation
    status: public
  - id: '14466'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Björn
  full_name: Hof, Björn
  id: 3A374330-F248-11E8-B48F-1D18A9856A87
  last_name: Hof
  orcid: 0000-0003-2057-2754
title: 'Transition to turbulence : Data-, solution-, and pattern-driven approaches'
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2025'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '19795'
abstract:
- lang: eng
  text: Super-resolution microscopy often entails long acquisition times of minutes
    to hours. Since drifts during the acquisition adversely affect data quality, active
    sample stabilization is commonly used for some of these techniques to reach their
    full potential. Although drifts in the lateral plane can often be corrected after
    acquisition, this is not always possible or may come with drawbacks. Therefore,
    it is appealing to stabilize sample position in three dimensions (3D) during acquisition.
    Various schemes for active sample stabilization have been demonstrated previously,
    with some reaching sub-nanometer stability in 3D. Here, we present a scheme for
    active drift correction that delivers the nanometer-scale 3D stability demanded
    by state-of-the-art super-resolution techniques and is straightforward to implement
    compared to previous schemes capable of reaching this level of stabilization precision.
    Using a refined algorithm that can handle various types of reference structure,
    without sparse signal peaks being mandatory, we stabilized sample position to
    ∼1 nm in 3D using objective lenses both with high and low numerical aperture.
    Our implementation requires only the addition of a simple widefield imaging path
    and we provide an open-source control software with graphical user interface to
    facilitate easy adoption of the module. Finally, we demonstrate how this has the
    potential to enhance data collection for diffraction-limited and super-resolution
    imaging techniques using single-molecule localization microscopy and cryo-confocal
    imaging as showcases.
acknowledged_ssus:
- _id: M-Shop
- _id: EM-Fac
- _id: LifeSc
acknowledgement: 'We acknowledge expert support by ISTA’s scientific service units,
  including the Miba Machine Shop, the Electron Microscopy Facility, and the Lab Support
  Facility. This work has been made possible in part by CZI grant DAF2021-234754 and
  grant DOI: https://doi.org/10.37921/812628ebpcwg from the Chan Zuckerberg Initiative
  DAF, an advised fund of Silicon Valley Community Foundation (funder DOI: https://doi.org/10.13039/100014989)
  (F.K.M.S. and J.G.D.). We further gratefully acknowledge funding by the following
  sources: Austrian Science Fund (FWF) grant DK W1232 (M.R.T. and J.G.D.); Austrian
  Academy of Sciences DOC fellowship 26137 (M.R.T.); Marie Skłodowska-Curie Actions
  Fellowship GA no. 665385 under the EU Horizon 2020 program (J.L.); ISTA postdoctoral
  fellowship IST fellow (A.W.); and Human Frontier Science Program postdoctoral fellowship
  LT000557/2018 (W.J.).'
article_number: '100211'
article_processing_charge: Yes
article_type: original
author:
- first_name: Jakob
  full_name: Vorlaufer, Jakob
  id: 937696FA-C996-11E9-8C7C-CF13E6697425
  last_name: Vorlaufer
  orcid: 0009-0000-7590-3501
- first_name: Nikolai
  full_name: Semenov, Nikolai
  id: e64d39c7-72ef-11ef-b75a-ee3046860d1b
  last_name: Semenov
- first_name: Caroline
  full_name: Kreuzinger, Caroline
  id: 382077BA-F248-11E8-B48F-1D18A9856A87
  last_name: Kreuzinger
- first_name: Manjunath
  full_name: Javoor, Manjunath
  id: 305ab18b-dc7d-11ea-9b2f-b58195228ea2
  last_name: Javoor
  orcid: 0000-0003-2311-2112
- first_name: Bettina
  full_name: Zens, Bettina
  id: 45FD126C-F248-11E8-B48F-1D18A9856A87
  last_name: Zens
  orcid: 0000-0002-9561-1239
- first_name: Nathalie
  full_name: Agudelo Duenas, Nathalie
  id: 40E7F008-F248-11E8-B48F-1D18A9856A87
  last_name: Agudelo Duenas
- first_name: Mojtaba
  full_name: Tavakoli, Mojtaba
  id: 3A0A06F4-F248-11E8-B48F-1D18A9856A87
  last_name: Tavakoli
  orcid: 0000-0002-7667-6854
- first_name: Marek
  full_name: Suplata, Marek
  id: EE8452B8-C26A-11E9-B157-E80CE6697425
  last_name: Suplata
- first_name: Wiebke
  full_name: Jahr, Wiebke
  id: 425C1CE8-F248-11E8-B48F-1D18A9856A87
  last_name: Jahr
  orcid: 0000-0003-0201-2315
- first_name: Julia
  full_name: Lyudchik, Julia
  id: 46E28B80-F248-11E8-B48F-1D18A9856A87
  last_name: Lyudchik
- first_name: Andreas
  full_name: Wartak, Andreas
  id: 60aaa06c-3de5-11eb-9e53-baa88e955dcb
  last_name: Wartak
- first_name: Florian Km
  full_name: Schur, Florian Km
  id: 48AD8942-F248-11E8-B48F-1D18A9856A87
  last_name: Schur
  orcid: 0000-0003-4790-8078
- first_name: Johann G
  full_name: Danzl, Johann G
  id: 42EFD3B6-F248-11E8-B48F-1D18A9856A87
  last_name: Danzl
  orcid: 0000-0001-8559-3973
citation:
  ama: Vorlaufer J, Semenov N, Kreuzinger C, et al. Image-based 3D active sample stabilization
    on the nanometer scale for optical microscopy. <i>Biophysical Reports</i>. 2025;5(2).
    doi:<a href="https://doi.org/10.1016/j.bpr.2025.100211">10.1016/j.bpr.2025.100211</a>
  apa: Vorlaufer, J., Semenov, N., Kreuzinger, C., Javoor, M., Zens, B., Agudelo Duenas,
    N., … Danzl, J. G. (2025). Image-based 3D active sample stabilization on the nanometer
    scale for optical microscopy. <i>Biophysical Reports</i>. Elsevier. <a href="https://doi.org/10.1016/j.bpr.2025.100211">https://doi.org/10.1016/j.bpr.2025.100211</a>
  chicago: Vorlaufer, Jakob, Nikolai Semenov, Caroline Kreuzinger, Manjunath Javoor,
    Bettina Zens, Nathalie Agudelo Duenas, Mojtaba Tavakoli, et al. “Image-Based 3D
    Active Sample Stabilization on the Nanometer Scale for Optical Microscopy.” <i>Biophysical
    Reports</i>. Elsevier, 2025. <a href="https://doi.org/10.1016/j.bpr.2025.100211">https://doi.org/10.1016/j.bpr.2025.100211</a>.
  ieee: J. Vorlaufer <i>et al.</i>, “Image-based 3D active sample stabilization on
    the nanometer scale for optical microscopy,” <i>Biophysical Reports</i>, vol.
    5, no. 2. Elsevier, 2025.
  ista: Vorlaufer J, Semenov N, Kreuzinger C, Javoor M, Zens B, Agudelo Duenas N,
    Tavakoli M, Suplata M, Jahr W, Lyudchik J, Wartak A, Schur FK, Danzl JG. 2025.
    Image-based 3D active sample stabilization on the nanometer scale for optical
    microscopy. Biophysical Reports. 5(2), 100211.
  mla: Vorlaufer, Jakob, et al. “Image-Based 3D Active Sample Stabilization on the
    Nanometer Scale for Optical Microscopy.” <i>Biophysical Reports</i>, vol. 5, no.
    2, 100211, Elsevier, 2025, doi:<a href="https://doi.org/10.1016/j.bpr.2025.100211">10.1016/j.bpr.2025.100211</a>.
  short: J. Vorlaufer, N. Semenov, C. Kreuzinger, M. Javoor, B. Zens, N. Agudelo Duenas,
    M. Tavakoli, M. Suplata, W. Jahr, J. Lyudchik, A. Wartak, F.K. Schur, J.G. Danzl,
    Biophysical Reports 5 (2025).
corr_author: '1'
date_created: 2025-06-08T22:01:22Z
date_published: 2025-06-11T00:00:00Z
date_updated: 2026-04-07T11:48:07Z
day: '11'
ddc:
- '570'
department:
- _id: JoDa
- _id: GradSch
- _id: FlSc
- _id: EM-Fac
doi: 10.1016/j.bpr.2025.100211
ec_funded: 1
file:
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  date_created: 2025-06-10T07:24:46Z
  date_updated: 2025-06-10T07:24:46Z
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file_date_updated: 2025-06-10T07:24:46Z
has_accepted_license: '1'
intvolume: '         5'
issue: '2'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
project:
- _id: 62909c6f-2b32-11ec-9570-e1476aab5308
  grant_number: CZI01
  name: CryoMinflux-guided in-situ molecular census and structure determination
- _id: 6285a163-2b32-11ec-9570-8e204ca2dba5
  grant_number: '26137'
  name: Studying Organelle Structure and Function at Nanoscale Resolution with Expansion
    Microscopy
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
- _id: 26AA4EF2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: W1232-B24
  name: Molecular Drug Targets
- _id: 2668BFA0-B435-11E9-9278-68D0E5697425
  grant_number: LT00057
  name: High-speed 3D-nanoscopy to study the role of adhesion during 3D cell migration
publication: Biophysical Reports
publication_identifier:
  eissn:
  - 2667-0747
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
  record:
  - id: '20206'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Image-based 3D active sample stabilization on the nanometer scale for optical
  microscopy
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
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  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2025'
...
---
OA_place: publisher
_id: '18979'
abstract:
- lang: eng
  text: "Topological Data Analysis (TDA) is a discipline utilizing the mathematical
    field of topology to study data, most prominently collections of point sets. This
    thesis summarizes three projects related to computations in TDA.\r\n\r\nThe first
    one establishes a variant of TDA for chromatic point sets, where each point is
    given a color. For example, we are given positions of cells within a tumor microenvironment,
    and color the cancerous cells red, and the immune cells blue.\r\n\r\nThe aim is
    then to give a quantitative description of how the two or more sets of points
    spatially interact. Building on image, kernel and cokernel variants of persistent
    homology, we suggest six-packs of persistent diagrams as such a descriptor.\r\n\r\nWe
    describe a construction of a chromatic alpha complex, which enables  efficient
    computation of several variants of the six-packs. We give topological descriptions
    of natural subcomplexes of the chromatic alpha complex, and show that the radii
    of the simplices form a discrete Morse function. Finally, we provide an implementation
    of the presented chromatic TDA pipeline.\r\n\r\nThe second part aims to translate
    a powerful tool of sheaf theory to elementary terms using labeled matrices. The
    goal is to enable their use in computational settings. We show that derived categories
    of sheaves over finite posets have, up to isomorphism, unique objects---minimal
    injective resolutions---and give a concrete algorithm to compute them. We further
    describe simple algorithms to compute derived pushforwards and pullbacks for monotonic
    maps, and their proper variants for inclusions, and demonstrate their tractability
    by providing an implementation. Finally, we suggest a discrete definition of microsupport
    and show desirable properties inspired by discrete Morse theory.\r\n\r\nIn the
    last part, we present a collection of observations about collapses. We give a
    characterization of collapsibility in terms of unitriangular submatrices of the
    boundary matrix, a cotree-tree decomposition, and the optimal solution to a variant
    of the Procrustes problem. We establish relation between dual collapses and relative
    Morse theory and pose several open questions. Finally, focusing on complexes embedded
    in the three-dimensional Euclidean space, we describe a relation between the collapsibility
    and the triviality of a polygonal knot."
acknowledgement: "The research presented in this thesis was funded with the Wittgenstein
  Prize,\r\nAustrian Science Fund (FWF), grant no. Z 342-N31, and from the DFG Collaborative
  Research\r\nCenter TRR 109, ‘Discretization in Geometry and Dynamics’, Austrian
  Science Fund (FWF),\r\ngrant no. I 02979-N35.\r\n"
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Ondrej
  full_name: Draganov, Ondrej
  id: 2B23F01E-F248-11E8-B48F-1D18A9856A87
  last_name: Draganov
  orcid: 0000-0003-0464-3823
citation:
  ama: Draganov O. Structures and computations in topological data analysis. 2025.
    doi:<a href="https://doi.org/10.15479/at:ista:18979">10.15479/at:ista:18979</a>
  apa: Draganov, O. (2025). <i>Structures and computations in topological data analysis</i>.
    Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/at:ista:18979">https://doi.org/10.15479/at:ista:18979</a>
  chicago: Draganov, Ondrej. “Structures and Computations in Topological Data Analysis.”
    Institute of Science and Technology Austria, 2025. <a href="https://doi.org/10.15479/at:ista:18979">https://doi.org/10.15479/at:ista:18979</a>.
  ieee: O. Draganov, “Structures and computations in topological data analysis,” Institute
    of Science and Technology Austria, 2025.
  ista: Draganov O. 2025. Structures and computations in topological data analysis.
    Institute of Science and Technology Austria.
  mla: Draganov, Ondrej. <i>Structures and Computations in Topological Data Analysis</i>.
    Institute of Science and Technology Austria, 2025, doi:<a href="https://doi.org/10.15479/at:ista:18979">10.15479/at:ista:18979</a>.
  short: O. Draganov, Structures and Computations in Topological Data Analysis, Institute
    of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-01-31T17:04:40Z
date_published: 2025-02-03T00:00:00Z
date_updated: 2026-04-07T11:47:30Z
day: '03'
ddc:
- '514'
- '004'
degree_awarded: PhD
department:
- _id: GradSch
- _id: HeEd
doi: 10.15479/at:ista:18979
file:
- access_level: closed
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  file_name: Thesis.zip
  file_size: 11899491
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  creator: odragano
  date_created: 2025-02-04T16:22:07Z
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  file_id: '19000'
  file_name: Thesis.pdf
  file_size: 8857514
  relation: main_file
file_date_updated: 2025-02-04T16:22:07Z
has_accepted_license: '1'
keyword:
- topological data analysis
- chromatic point set
- alpha complex
- persistent homology
- six pack
- sheaf
- microlocal discrete Morse
- injective resolution
- collapse
- knot
- discrete Morse theory
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: '140'
project:
- _id: 2561EBF4-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I02979-N35
  name: Persistence and stability of geometric complexes
- _id: 268116B8-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Z00342
  name: Mathematics, Computer Science
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '15091'
    relation: part_of_dissertation
    status: public
  - id: '18981'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
title: Structures and computations in topological data analysis
tmp:
  image: /images/cc_by.png
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  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2025'
...
---
OA_place: publisher
_id: '20206'
abstract:
- lang: eng
  text: "The internal structure of biomolecules and their organization in higher-order
    arrangements are key factors governing the working principles of biological systems.
    Bioimaging has successfully revealed arrangements across relevant spatial scales.
    For example, cryo-electron tomography has become widely used for analyzing biomolecular
    structures in situ due to its comprehensive structural visualization of near-natively
    preserved samples, and its capability of sub-nm resolution via averaging. However,
    the identification of molecules within crowded cellular environments is often
    hindered by low contrast. Fluorescence microscopy, on the other hand, routinely
    visualizes specifically labeled targets at single-molecule contrast against essentially
    zero background. Moreover, it provides comparatively high throughput and is amenable
    to multiplexing. Due to this complementarity, combining datasets from both modalities
    acquired on the same region via correlative light and electron microscopy can
    reveal novel types of information. \r\nThe spatial scale at which information
    can be extracted depends on imaging resolution and correlation accuracy. Since
    diffraction of light limits the resolution of conventional fluorescence microscopy
    to few hundreds of nanometers, reaching the full potential of correlative imaging
    requires super-resolution approaches. Performing imaging at cryogenic temperature
    preserves structures in a near-native state and minimizes distortions between
    the fluorescence and the electron microscopy datasets. Implementations of this
    concept have achieved correlation on the scale of cellular organelles or bacterial
    domains.\r\nWe have worked towards pushing correlative imaging to the single-molecule
    scale by improving cryo-super-resolution microscopy, and devising a refined image
    correlation workflow. As part of this project, I constructed a microscopy setup
    and adopted it for super-resolution fluorescence microscopy at room temperature
    and cryogenic conditions. I explored different cryo-stages and acquisition strategies.
    Specifically, I developed a new scheme for correcting sample drift, thus increasing
    mechanical stability during microscopy acquisitions.\r\n"
acknowledged_ssus:
- _id: M-Shop
- _id: EM-Fac
- _id: Bio
acknowledgement: "The project was supported by CZI grant DAF2021-234754 and grant\r\nDOI:
  https://doi.org/10.37921/812628ebpcwg from the Chan Zuckerberg Initiative DAF, an\r\nadvised
  fund of Silicon Valley Community Foundation (funder\r\nDOI: https://doi.org/10.13039/100014989),
  as well as internal grants from ISTA’s Equipment\r\nInvestment Committee and Interdisciplinary
  Project Committee. "
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Jakob
  full_name: Vorlaufer, Jakob
  id: 937696FA-C996-11E9-8C7C-CF13E6697425
  last_name: Vorlaufer
  orcid: 0009-0000-7590-3501
citation:
  ama: Vorlaufer J. Construction of a cryo-super-resolution microscope to guide in
    situ structure analysis. 2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-20206">10.15479/AT-ISTA-20206</a>
  apa: Vorlaufer, J. (2025). <i>Construction of a cryo-super-resolution microscope
    to guide in situ structure analysis</i>. Institute of Science and Technology Austria.
    <a href="https://doi.org/10.15479/AT-ISTA-20206">https://doi.org/10.15479/AT-ISTA-20206</a>
  chicago: Vorlaufer, Jakob. “Construction of a Cryo-Super-Resolution Microscope to
    Guide in Situ Structure Analysis.” Institute of Science and Technology Austria,
    2025. <a href="https://doi.org/10.15479/AT-ISTA-20206">https://doi.org/10.15479/AT-ISTA-20206</a>.
  ieee: J. Vorlaufer, “Construction of a cryo-super-resolution microscope to guide
    in situ structure analysis,” Institute of Science and Technology Austria, 2025.
  ista: Vorlaufer J. 2025. Construction of a cryo-super-resolution microscope to guide
    in situ structure analysis. Institute of Science and Technology Austria.
  mla: Vorlaufer, Jakob. <i>Construction of a Cryo-Super-Resolution Microscope to
    Guide in Situ Structure Analysis</i>. Institute of Science and Technology Austria,
    2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-20206">10.15479/AT-ISTA-20206</a>.
  short: J. Vorlaufer, Construction of a Cryo-Super-Resolution Microscope to Guide
    in Situ Structure Analysis, Institute of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-08-22T08:12:55Z
date_published: 2025-08-25T00:00:00Z
date_updated: 2026-04-07T11:48:07Z
day: '25'
ddc:
- '621'
- '535'
degree_awarded: PhD
department:
- _id: GradSch
- _id: JoDa
doi: 10.15479/AT-ISTA-20206
file:
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  date_created: 2025-08-25T13:49:55Z
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  file_name: 2025_Vorlaufer_Jakob_Thesis.docx
  file_size: 39735535
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  checksum: 104400e6036921569610230c1d4899dc
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  creator: jvorlauf
  date_created: 2025-08-25T13:49:56Z
  date_updated: 2025-08-25T13:49:56Z
  file_id: '20229'
  file_name: 2025_Vorlaufer_Jakob_Thesis.pdf
  file_size: 10947446
  relation: main_file
  success: 1
file_date_updated: 2025-08-25T13:49:56Z
has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-sa/4.0/
month: '08'
oa: 1
oa_version: Published Version
page: '107'
project:
- _id: 62909c6f-2b32-11ec-9570-e1476aab5308
  grant_number: CZI01
  name: CryoMinflux-guided in-situ molecular census and structure determination
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '19795'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Johann G
  full_name: Danzl, Johann G
  id: 42EFD3B6-F248-11E8-B48F-1D18A9856A87
  last_name: Danzl
  orcid: 0000-0001-8559-3973
title: Construction of a cryo-super-resolution microscope to guide in situ structure
  analysis
tmp:
  image: /images/cc_by_nc_sa.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
    BY-NC-SA 4.0)
  short: CC BY-NC-SA (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2025'
...
---
OA_embargo: '12'
OA_place: publisher
_id: '19722'
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
acknowledgement: Special thanks to the Plant Facility.
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Syamala
  full_name: Inumella, Syamala
  id: F8660870-D756-11E9-98C5-34DFE5697425
  last_name: Inumella
  orcid: 0009-0002-5890-120X
citation:
  ama: Inumella S. Molecular mechanisms of microtubule reorganization in elongating
    root epidermal cells. 2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-19722">10.15479/AT-ISTA-19722</a>
  apa: Inumella, S. (2025). <i>Molecular mechanisms of microtubule reorganization
    in elongating root epidermal cells</i>. Institute of Science and Technology Austria.
    <a href="https://doi.org/10.15479/AT-ISTA-19722">https://doi.org/10.15479/AT-ISTA-19722</a>
  chicago: Inumella, Syamala. “Molecular Mechanisms of Microtubule Reorganization
    in Elongating Root Epidermal Cells.” Institute of Science and Technology Austria,
    2025. <a href="https://doi.org/10.15479/AT-ISTA-19722">https://doi.org/10.15479/AT-ISTA-19722</a>.
  ieee: S. Inumella, “Molecular mechanisms of microtubule reorganization in elongating
    root epidermal cells,” Institute of Science and Technology Austria, 2025.
  ista: Inumella S. 2025. Molecular mechanisms of microtubule reorganization in elongating
    root epidermal cells. Institute of Science and Technology Austria.
  mla: Inumella, Syamala. <i>Molecular Mechanisms of Microtubule Reorganization in
    Elongating Root Epidermal Cells</i>. Institute of Science and Technology Austria,
    2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-19722">10.15479/AT-ISTA-19722</a>.
  short: S. Inumella, Molecular Mechanisms of Microtubule Reorganization in Elongating
    Root Epidermal Cells, Institute of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-05-23T15:21:29Z
date_published: 2025-05-23T00:00:00Z
date_updated: 2026-04-07T11:47:52Z
day: '23'
ddc:
- '580'
degree_awarded: PhD
department:
- _id: GradSch
- _id: EvBe
doi: 10.15479/AT-ISTA-19722
file:
- access_level: closed
  checksum: 847ec70b2e40f50e0ddc7b8da201d52c
  content_type: application/pdf
  creator: sinumell
  date_created: 2025-05-28T11:59:11Z
  date_updated: 2025-05-28T11:59:11Z
  embargo: 2026-05-23
  embargo_to: open_access
  file_id: '19757'
  file_name: Final Thesis_Syamala Inumella.pdf
  file_size: 8292363
  relation: main_file
- access_level: closed
  checksum: 17cdffdae13a5f65bdad9c84e9e0e3bd
  content_type: application/vnd.openxmlformats-officedocument.wordprocessingml.document
  creator: sinumell
  date_created: 2025-05-28T11:59:11Z
  date_updated: 2025-05-28T11:59:11Z
  file_id: '19758'
  file_name: Final Thesis_Syamala Inumella.docx
  file_size: 7145703
  relation: source_file
file_date_updated: 2025-05-28T11:59:11Z
has_accepted_license: '1'
language:
- iso: eng
month: '05'
oa_version: Published Version
page: '113'
publication_identifier:
  isbn:
  - 978-3-99078-059-6
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
status: public
supervisor:
- first_name: Eva
  full_name: Benková, Eva
  id: 38F4F166-F248-11E8-B48F-1D18A9856A87
  last_name: Benková
  orcid: 0000-0002-8510-9739
title: Molecular mechanisms of microtubule reorganization in elongating root epidermal
  cells
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2025'
...
---
OA_place: publisher
_id: '19395'
abstract:
- lang: eng
  text: "Plant growth and development rely significantly on phytohormones, with auxin
    serving as a master regulator, orchestrating processes from embryogenesis to organogenesis,
    vascular patterning, and environmental adaptation. Since its conceptual proposition
    by Charles Darwin in 1880 as an endogenous chemical signal influencing phototropism
    in grass, auxin has captivated scientists seeking to understand how such a small
    molecule exerts a profound influence on plant development.\r\nOne particularly
    fascinating aspect of auxin function is its ability to self-organize its transport.
    Through a feedback mechanism between auxin perception and directional transport—primarily
    mediated by PIN auxin transporters—auxin establishes narrow transport channels.
    This phenomenon, known as auxin canalization, is fundamental to vascular formation,
    regeneration, and other key developmental processes. Despite advances in our understanding,
    driven by experimental studies and computational models, auxin canalization remains
    an enigma, with many unanswered questions.\r\nLike other hormones, auxin functions
    through intricate signaling pathways. It operates through at least two distinct
    signaling mechanisms: the well-characterized canonical pathway and the less understood
    non-canonical pathway. While significant progress has been made in elucidating
    the canonical pathway, the non-canonical mechanisms remain less defined and require
    further investigation.\r\nIn this study, we revisit the non-canonical auxin signaling
    pathway mediated by the cell-surface complex Auxin Binding Protein 1-Transmembrane
    Kinase 1 (ABP1-TMK1), with a particular focus on its downstream phosphorylation
    events. We reveal that this auxin-mediated phosphorylation is conserved across
    the green lineage, underscoring its fundamental role in plant development. We
    explore key phosphorylation targets, particularly PIN2, which is essential for
    root gravitropism. To further understand TMK1’s role in diverse developmental
    processes, we identified and investigated its interactors as potential co-receptors
    or regulatory components within its signaling network.\r\nGiven the previously
    established role of ABP1-TMK1 in auxin canalization, we sought to further investigate
    this process and identified several TMK1 interactors also involved in this intricate
    mechanism.\r\nThese findings provide new insights into the complex regulation
    of auxin canalization, highlighting a broader and more interconnected signaling
    framework than previously understood."
acknowledged_ssus:
- _id: LifeSc
- _id: Bio
acknowledgement: I would like to acknowledge the facilities at ISTA, particularly
  LSF, IOF, and, of course, the plant facility, for providing the necessary resources
  for my research.
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Aline
  full_name: Monzer, Aline
  id: 2DB5D88C-D7B3-11E9-B8FD-7907E6697425
  last_name: Monzer
citation:
  ama: 'Monzer A. Cell-Surface Auxin Signaling: Linking molecular pathways to plant
    development. 2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-19395">10.15479/AT-ISTA-19395</a>'
  apa: 'Monzer, A. (2025). <i>Cell-Surface Auxin Signaling: Linking molecular pathways
    to plant development</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-19395">https://doi.org/10.15479/AT-ISTA-19395</a>'
  chicago: 'Monzer, Aline. “Cell-Surface Auxin Signaling: Linking Molecular Pathways
    to Plant Development.” Institute of Science and Technology Austria, 2025. <a href="https://doi.org/10.15479/AT-ISTA-19395">https://doi.org/10.15479/AT-ISTA-19395</a>.'
  ieee: 'A. Monzer, “Cell-Surface Auxin Signaling: Linking molecular pathways to plant
    development,” Institute of Science and Technology Austria, 2025.'
  ista: 'Monzer A. 2025. Cell-Surface Auxin Signaling: Linking molecular pathways
    to plant development. Institute of Science and Technology Austria.'
  mla: 'Monzer, Aline. <i>Cell-Surface Auxin Signaling: Linking Molecular Pathways
    to Plant Development</i>. Institute of Science and Technology Austria, 2025, doi:<a
    href="https://doi.org/10.15479/AT-ISTA-19395">10.15479/AT-ISTA-19395</a>.'
  short: 'A. Monzer, Cell-Surface Auxin Signaling: Linking Molecular Pathways to Plant
    Development, Institute of Science and Technology Austria, 2025.'
corr_author: '1'
date_created: 2025-03-12T14:25:42Z
date_published: 2025-03-13T00:00:00Z
date_updated: 2026-04-07T11:48:32Z
day: '13'
ddc:
- '580'
degree_awarded: PhD
department:
- _id: GradSch
- _id: JiFr
doi: 10.15479/AT-ISTA-19395
file:
- access_level: open_access
  checksum: 9a3dd03bb4ec6b9907a325c3c4e8a1d7
  content_type: application/pdf
  creator: amonzer
  date_created: 2025-03-12T14:14:49Z
  date_updated: 2025-03-12T14:14:49Z
  file_id: '19396'
  file_name: Final Thesis Aline Monzer.pdf
  file_size: 13119670
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  success: 1
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  checksum: a353ce1ee2eabce37bca35499e76dbf1
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  creator: amonzer
  date_created: 2025-03-12T14:15:19Z
  date_updated: 2025-04-01T07:55:27Z
  file_id: '19397'
  file_name: Thesis Aline.docx
  file_size: 13774837
  relation: source_file
file_date_updated: 2025-04-01T07:55:27Z
has_accepted_license: '1'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: '160'
publication_identifier:
  eisbn:
  - 978-3-99078-054-1
  eissn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '19398'
    relation: part_of_dissertation
    status: public
  - id: '19399'
    relation: part_of_dissertation
    status: public
  - id: '12291'
    relation: part_of_dissertation
    status: public
  - id: '14826'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
title: 'Cell-Surface Auxin Signaling: Linking molecular pathways to plant development'
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '19398'
abstract:
- lang: eng
  text: Receptor-like kinases (RLKs), particularly the Transmembrane Kinase (TMK)
    family, play essential roles in signaling and development, with TMKs being key
    components of auxin perception and downstream phosphorylation events. While TMKs’
    involvement in auxin canalization, a process essential for vasculature formation
    and regeneration, has been established, nonetheless, the additional signaling
    and regulatory partners remain poorly understood. In this study, we identify and
    characterize seven leucine-rich repeat RLKs (TINT1–TINT7) as novel interactors
    of TMK1, revealing their diverse evolutionary, structural, and functional characteristics.
    Our results show that TINTs interact with TMK1 and highlight their roles in regulating
    various developmental processes. Majority of TINTs contributes, together with
    TMK1, to auxin canalization, with TINT5 linking TMK1 to other canalization component
    CAMEL. Beyond canalization, we also establish the role of TINT-TMK1 interactions
    in processes such as stomatal movement and the hypocotyl’s gravitropic response.
    These findings suggest that TINTs, through their interaction with TMK1, are integral
    components of various signaling networks, contributing to both auxin canalization
    and broader plant development.
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
acknowledgement: We deeply appreciate M. Wrzaczek’s constructive input and insightful
  discussions, which significantly enriched this work. We thank L. Fiedler for helping
  with the heat map and for the discussions. We also thank the facilities at ISTA,
  the imaging and optics (IOF) and Lab Support (LSF) facilities for their service
  and assistance.
article_processing_charge: No
author:
- first_name: Aline
  full_name: Monzer, Aline
  id: 2DB5D88C-D7B3-11E9-B8FD-7907E6697425
  last_name: Monzer
- first_name: Ewa
  full_name: Mazur, Ewa
  last_name: Mazur
- first_name: Lesia
  full_name: Rodriguez Solovey, Lesia
  id: 3922B506-F248-11E8-B48F-1D18A9856A87
  last_name: Rodriguez Solovey
  orcid: 0000-0002-7244-7237
- first_name: Michelle C
  full_name: Gallei, Michelle C
  id: 35A03822-F248-11E8-B48F-1D18A9856A87
  last_name: Gallei
  orcid: 0000-0003-1286-7368
- first_name: Minxia
  full_name: Zou, Minxia
  id: 5c243f41-03f3-11ec-841c-96faf48a7ef9
  last_name: Zou
- first_name: Michael
  full_name: Smejkal, Michael
  id: 79a5a1be-04a3-11f0-ba18-a1730e0b58e9
  last_name: Smejkal
- first_name: Ema
  full_name: Cervenova, Ema
  id: 9f185b95-04a3-11f0-8245-f5e32eeb470f
  last_name: Cervenova
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Monzer A, Mazur E, Rodriguez Solovey L, et al. TMK interacting network of receptor
    like kinases for auxin canalization and beyond. <i>bioRxiv</i>. doi:<a href="https://doi.org/10.1101/2025.02.28.640727">10.1101/2025.02.28.640727</a>
  apa: Monzer, A., Mazur, E., Rodriguez Solovey, L., Gallei, M. C., Zou, M., Smejkal,
    M., … Friml, J. (n.d.). TMK interacting network of receptor like kinases for auxin
    canalization and beyond. <i>bioRxiv</i>. Cold Spring Harbor Laboratory. <a href="https://doi.org/10.1101/2025.02.28.640727">https://doi.org/10.1101/2025.02.28.640727</a>
  chicago: Monzer, Aline, Ewa Mazur, Lesia Rodriguez Solovey, Michelle C Gallei, Minxia
    Zou, Michael Smejkal, Ema Cervenova, and Jiří Friml. “TMK Interacting Network
    of Receptor like Kinases for Auxin Canalization and Beyond.” <i>BioRxiv</i>. Cold
    Spring Harbor Laboratory, n.d. <a href="https://doi.org/10.1101/2025.02.28.640727">https://doi.org/10.1101/2025.02.28.640727</a>.
  ieee: A. Monzer <i>et al.</i>, “TMK interacting network of receptor like kinases
    for auxin canalization and beyond,” <i>bioRxiv</i>. Cold Spring Harbor Laboratory.
  ista: Monzer A, Mazur E, Rodriguez Solovey L, Gallei MC, Zou M, Smejkal M, Cervenova
    E, Friml J. TMK interacting network of receptor like kinases for auxin canalization
    and beyond. bioRxiv, <a href="https://doi.org/10.1101/2025.02.28.640727">10.1101/2025.02.28.640727</a>.
  mla: Monzer, Aline, et al. “TMK Interacting Network of Receptor like Kinases for
    Auxin Canalization and Beyond.” <i>BioRxiv</i>, Cold Spring Harbor Laboratory,
    doi:<a href="https://doi.org/10.1101/2025.02.28.640727">10.1101/2025.02.28.640727</a>.
  short: A. Monzer, E. Mazur, L. Rodriguez Solovey, M.C. Gallei, M. Zou, M. Smejkal,
    E. Cervenova, J. Friml, BioRxiv (n.d.).
corr_author: '1'
date_created: 2025-03-12T14:28:53Z
date_published: 2025-03-02T00:00:00Z
date_updated: 2026-04-07T11:48:31Z
day: '02'
department:
- _id: GradSch
- _id: JiFr
- _id: EvBe
doi: 10.1101/2025.02.28.640727
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/2025.02.28.640727
month: '03'
oa: 1
oa_version: Published Version
publication: bioRxiv
publication_status: draft
publisher: Cold Spring Harbor Laboratory
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title: TMK interacting network of receptor like kinases for auxin canalization and
  beyond
tmp:
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  short: CC BY-NC-ND (4.0)
type: preprint
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year: '2025'
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---
OA_place: publisher
OA_type: gold
_id: '19393'
abstract:
- lang: eng
  text: "Rotations constitute one of the fundamental symmetries in physics, characterized
    by their intricate group structure and infinite dimensional representations. In
    contrast to classical rotations, quantum mechanics unveils the SO(3) symmetry
    group structure, manifesting in phenomena without classical counterparts, from
    angular momentum quantization to non-trivial addition of angular momenta.\r\nWhile
    most studies of topological physics have focused on two-band systems, the SO(3)
    symmetry group of quantum rotors offers an inherently more complex platform with
    unprecedented possibilities for exploring topological phenomena. Despite their
    ubiquity in nature– from molecules to nanorotors– their potential for hosting
    topological phases has remained largely unexamined.\r\nIn this thesis, we mainly
    focus on periodically driven linear molecules as a prototype for studying topological
    phenomena in quantum rotors. Recent technological advances in coherent control
    of molecules, particularly through precisely shaped laser pulses, have made it
    possible to investigate linear rotors in the context of topology. While planar
    rotors have received some attention in recent years, threedimensional rotors–particularly
    linear molecules–harbor substantially richer topological phenomena due to their
    non-abelian nature and their additional angular degrees of freedom. We demonstrate
    that these systems can host novel edge states and topological features fundamentally
    impossible in planar systems.\r\nWe begin by establishing a theoretical bridge
    between periodically kicked rotors and \"crystalline\" lattices in angular momentum
    space. Using non-interacting linear molecules as our primary example, we show
    how quantum interference and revival patterns lead to the possibility to simulate
    band models with arbitrary number of bands N. While our framework applies to various
    quantum rotors, including nanorotors and kicked Bose-Einstein condensates, linear\r\nmolecules
    provide an ideal experimental platform due to their abovementioned precise controllability.\r\nThe
    core of this work examines adiabatic dynamics of 3D quantum rotors, establishing
    a geometric framework based on the Euler class to characterize its non-abelian
    topology. The non-Hermitian nature of the system enables novel braiding behaviors
    and topological transitions impossible in static systems, leading to an anomalous
    Dirac string phase with edge states in each gap, even though the Berry phases
    are all zero. These features can be directly observed through\r\nmolecular alignment
    and rotational level populations.\r\nThese findings establish quantum rotors as
    an alternative platform for studying multi-band topological physics, while suggesting
    practical implementations for quantum computation where topological protection
    could offer natural resilience against decoherence. The rich structure of three-dimensional
    rotation groups, combined with the tunability of topological features through
    driving parameters, makes this platform particularly valuable for exploring fundamental\r\nphysics
    and developing quantum technologies."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Volker
  full_name: Karle, Volker
  id: D7C012AE-D7ED-11E9-95E8-1EC5E5697425
  last_name: Karle
  orcid: 0000-0002-6963-0129
citation:
  ama: Karle V. Non-equilibrium topological phases with periodically driven molecules
    and quantum rotors. 2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-19393">10.15479/AT-ISTA-19393</a>
  apa: Karle, V. (2025). <i>Non-equilibrium topological phases with periodically driven
    molecules and quantum rotors</i>. Institute of Science and Technology Austria.
    <a href="https://doi.org/10.15479/AT-ISTA-19393">https://doi.org/10.15479/AT-ISTA-19393</a>
  chicago: Karle, Volker. “Non-Equilibrium Topological Phases with Periodically Driven
    Molecules and Quantum Rotors.” Institute of Science and Technology Austria, 2025.
    <a href="https://doi.org/10.15479/AT-ISTA-19393">https://doi.org/10.15479/AT-ISTA-19393</a>.
  ieee: V. Karle, “Non-equilibrium topological phases with periodically driven molecules
    and quantum rotors,” Institute of Science and Technology Austria, 2025.
  ista: Karle V. 2025. Non-equilibrium topological phases with periodically driven
    molecules and quantum rotors. Institute of Science and Technology Austria.
  mla: Karle, Volker. <i>Non-Equilibrium Topological Phases with Periodically Driven
    Molecules and Quantum Rotors</i>. Institute of Science and Technology Austria,
    2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-19393">10.15479/AT-ISTA-19393</a>.
  short: V. Karle, Non-Equilibrium Topological Phases with Periodically Driven Molecules
    and Quantum Rotors, Institute of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-03-12T13:04:59Z
date_published: 2025-03-13T00:00:00Z
date_updated: 2026-04-07T11:48:53Z
day: '13'
ddc:
- '530'
degree_awarded: PhD
department:
- _id: GradSch
- _id: MiLe
doi: 10.15479/AT-ISTA-19393
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oa: 1
oa_version: Published Version
page: '192'
publication_identifier:
  eissn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
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    relation: part_of_dissertation
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    relation: part_of_dissertation
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    relation: part_of_dissertation
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  - id: '9903'
    relation: part_of_dissertation
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  - id: '15004'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Mikhail
  full_name: Lemeshko, Mikhail
  id: 37CB05FA-F248-11E8-B48F-1D18A9856A87
  last_name: Lemeshko
  orcid: 0000-0002-6990-7802
title: Non-equilibrium topological phases with periodically driven molecules and quantum
  rotors
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2025'
...
---
OA_place: publisher
_id: '20138'
abstract:
- lang: eng
  text: "The evolution shapes the world around us.\r\nNot only in biology, where the
    fittest individuals spread their genes but also in physics and social dynamics,
    the evolutionary forces determine the development of a state of matter or public
    opinions.\r\nMany models describe these dynamics.\r\nThis thesis examines the
    role of the structure in the models of selection.\r\nThe population structure
    is represented as a graph or a network, and each vertex is occupied by one individual.\r\nEvery
    individual has a type and fitness that represents the reproductive potential and
    depends on the type, occupied vertex, and the arrangement of the neighbors.\r\nThe
    evolution is modeled in discrete steps; in one step, one individual is replaced
    by a neighbor selected randomly with the influence of fitness.\r\n\r\n\r\n\r\nThe
    role of the networks is widely examined in the literature.\r\nThe structures that
    promote the spread of the desired type compared to the structureless case are
    called amplifiers.\r\nThe existence of amplifiers in various settings is an intensively
    studied topic, and in some settings, the amplifiers have been identified.\r\nMoreover,
    there are other important questions about the number of steps until one type spreads
    over the whole network (fixation time), the computational complexity, and the
    questions about the robustness of these processes.\r\n\r\n\r\nThis thesis explores
    the role of structure in evolution from many perspectives.\r\nFirst, it introduces
    different models and various choices that can be made in the models of evolution.\r\nIt
    highlights the role of the structure in the real world and how this is reflected
    in these models.\r\nThen, it describes the previous results and open problems.\r\nSecond,
    the thesis describes an amplifier for two variants of the Moran process: one with
    a constant birth rate and the other with a constant death rate.\r\nThis is an
    important contribution to the robustness of the amplification.\r\nThird, the thesis
    determines the complexity of spatial games.\r\nThese are processes where the fitness
    comes from a game, and the strength of selection is high.\r\nIt shows that determining
    the fate of cooperation in these games is a PSPACE-complete problem.\r\nFourth,
    the thesis describes the amplifier of cooperation for spatial games.\r\nThis is
    the first amplifier in this setting.\r\nFifth, the thesis examines the coexistence
    in the Moran process with environmental heterogeneity.\r\nIn this setting, the
    fitness depends not only on the type of the individual but also on the occupied
    vertex.\r\nThe chapter determines the relationship between the interactions of
    vertices of different types and the coexistence time.\r\nSixth, the thesis examines
    the social balance on networks and proposes a stochastic dynamic partially aware
    of the state of the graph, which reaches a balanced position quickly.\r\nFinally,
    the thesis presents conclusions and outlines the directions for future work.\r\n\r\n\r\n"
acknowledgement: "This work was supported by the European Research Council CoG 863818
  (ForMSMArt) and Austrian Science Fund 10.55776/COE12.\r\n"
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Jakub
  full_name: Svoboda, Jakub
  id: 130759D2-D7DD-11E9-87D2-DE0DE6697425
  last_name: Svoboda
  orcid: 0000-0002-1419-3267
citation:
  ama: Svoboda J. Structural properties of games on graphs. 2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-20138">10.15479/AT-ISTA-20138</a>
  apa: Svoboda, J. (2025). <i>Structural properties of games on graphs</i>. Institute
    of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-20138">https://doi.org/10.15479/AT-ISTA-20138</a>
  chicago: Svoboda, Jakub. “Structural Properties of Games on Graphs.” Institute of
    Science and Technology Austria, 2025. <a href="https://doi.org/10.15479/AT-ISTA-20138">https://doi.org/10.15479/AT-ISTA-20138</a>.
  ieee: J. Svoboda, “Structural properties of games on graphs,” Institute of Science
    and Technology Austria, 2025.
  ista: Svoboda J. 2025. Structural properties of games on graphs. Institute of Science
    and Technology Austria.
  mla: Svoboda, Jakub. <i>Structural Properties of Games on Graphs</i>. Institute
    of Science and Technology Austria, 2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-20138">10.15479/AT-ISTA-20138</a>.
  short: J. Svoboda, Structural Properties of Games on Graphs, Institute of Science
    and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-08-05T14:33:59Z
date_published: 2025-08-05T00:00:00Z
date_updated: 2026-04-07T11:49:12Z
day: '05'
ddc:
- '000'
- '519'
degree_awarded: PhD
department:
- _id: GradSch
- _id: KrCh
doi: 10.15479/AT-ISTA-20138
ec_funded: 1
file:
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  file_id: '20178'
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language:
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month: '08'
oa: 1
oa_version: Published Version
page: '167'
project:
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '863818'
  name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
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    relation: part_of_dissertation
    status: public
  - id: '15297'
    relation: part_of_dissertation
    status: public
  - id: '18703'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
title: Structural properties of games on graphs
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  short: CC BY-NC-SA (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2025'
...
---
OA_place: publisher
_id: '20117'
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
- _id: PreCl
acknowledgement: "I would also like to acknowledge the invaluable assistance provided
  by the Plant\r\nFacility, Imaging & Optics Facility, and the Lab Support Facility.
  The technical support and\r\nresources offered by these facilities were indispensable
  to the successful completion of my\r\nexperiments."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Yiqun
  full_name: Wang, Yiqun
  id: 82F537F2-B517-11E9-84D7-6433E6697425
  last_name: Wang
citation:
  ama: Wang Y. The role of dynamin related protein 2A in cytokinin regulated plant
    growth and development. 2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-20117">10.15479/AT-ISTA-20117</a>
  apa: Wang, Y. (2025). <i>The role of dynamin related protein 2A in cytokinin regulated
    plant growth and development</i>. Institute of Science and Technology Austria.
    <a href="https://doi.org/10.15479/AT-ISTA-20117">https://doi.org/10.15479/AT-ISTA-20117</a>
  chicago: Wang, Yiqun. “The Role of Dynamin Related Protein 2A in Cytokinin Regulated
    Plant Growth and Development.” Institute of Science and Technology Austria, 2025.
    <a href="https://doi.org/10.15479/AT-ISTA-20117">https://doi.org/10.15479/AT-ISTA-20117</a>.
  ieee: Y. Wang, “The role of dynamin related protein 2A in cytokinin regulated plant
    growth and development,” Institute of Science and Technology Austria, 2025.
  ista: Wang Y. 2025. The role of dynamin related protein 2A in cytokinin regulated
    plant growth and development. Institute of Science and Technology Austria.
  mla: Wang, Yiqun. <i>The Role of Dynamin Related Protein 2A in Cytokinin Regulated
    Plant Growth and Development</i>. Institute of Science and Technology Austria,
    2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-20117">10.15479/AT-ISTA-20117</a>.
  short: Y. Wang, The Role of Dynamin Related Protein 2A in Cytokinin Regulated Plant
    Growth and Development, Institute of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-08-04T15:24:21Z
date_published: 2025-08-04T00:00:00Z
date_updated: 2026-04-07T11:49:34Z
day: '04'
ddc:
- '580'
degree_awarded: PhD
department:
- _id: GradSch
- _id: EvBe
doi: 10.15479/AT-ISTA-20117
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  date_updated: 2025-09-03T09:36:52Z
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language:
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month: '08'
oa_version: Published Version
page: '108'
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
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    status: public
status: public
supervisor:
- first_name: Eva
  full_name: Benková, Eva
  id: 38F4F166-F248-11E8-B48F-1D18A9856A87
  last_name: Benková
  orcid: 0000-0002-8510-9739
title: The role of dynamin related protein 2A in cytokinin regulated plant growth
  and development
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2025'
...
---
OA_place: publisher
_id: '19759'
abstract:
- lang: eng
  text: "Despite generating remarkable results in various computer vision tasks, deep
    learning comes\r\nwith some surprising shortcomings. For example, tiny perturbations,
    often imperceptible to\r\nthe human eye, can completely change the predictions
    of image classifiers. Despite a decade\r\nof research, the field has made limited
    progress in developing image classifiers that are both\r\naccurate and robust.
    This thesis aims to address this gap.\r\nAs our first contribution, we aim to
    simplify the process of training certifiably robust image\r\nclassifiers. We do
    this by designing a convolutional layer that does not require executing an\r\niterative
    procedure in every forward pass, but relies on an explicit bound instead. We also\r\npropose
    a loss function that allows optimizing for a particular margin more precisely.\r\nNext,
    we provide an overview and comparison of various methods that create robust image\r\nclassifiers
    by constraining the Lipschitz constant. This is important since generally longer\r\ntraining
    times and more parameters improve the performance of robust classifiers, making
    it\r\nchallenging to determine the most practical and effective methods from existing
    literature.\r\nIn 1-Lipschitz classification, the performance of current methods
    is still much worse than what\r\nwe expect on the simple tasks we consider. Therefore,
    we next investigate potential causes of\r\nthis shortcoming. We first consider
    the role of the activation function. We prove a theoretical\r\nshortcoming of
    the commonly used activation function, and provide an alternative without it.\r\nHowever
    this theoretical improvement does barely translate to the empirical performance
    of\r\nrobust classifiers, suggesting a different bottleneck.\r\nTherefore, in
    the final chapter, we study how the performance depends on the amount of\r\ntraining
    data. We prove that in the worst case, we might require far more data to train
    a\r\nrobust classifier compared to a normal one. We furthermore find that the
    amount of training\r\ndata is a key determinant of the performance current methods
    achieve on popular datasets.\r\nAdditionally, we show that linear subspaces exist
    with tiny data variance, and yet we can\r\nstill train very accurate classifiers
    after projecting into those subspaces. This shows that on\r\nthe datasets considered,
    enforcing robustness in classification makes the task strictly more\r\nchallenging.\r\n\r\n-----------------“In
    reference to IEEE copyrighted material which is used with permission in this thesis,
    the IEEE does not endorse any of [name of university or educational entity]’s
    products or services. Internal or personal use of this material is permitted.
    If interested in reprinting/republishing IEEE copyrighted material for advertising
    or promotional purposes or for creating new collective works for resale or redistribution,
    please go to http://www.ieee.org/publications_standards/publications/rights/rights_link.html
    to learn how to obtain a License from RightsLink. If applicable, University Microfilms
    and/or ProQuest Library, or the Archives of Canada may supply single copies of
    the dissertation.”\r\n"
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Bernd
  full_name: Prach, Bernd
  id: 2D561D42-C427-11E9-89B4-9C1AE6697425
  last_name: Prach
citation:
  ama: Prach B. Robust image classification with 1-Lipschitz networks. 2025. doi:<a
    href="https://doi.org/10.15479/10.15479/at-ista-19759">10.15479/10.15479/at-ista-19759</a>
  apa: Prach, B. (2025). <i>Robust image classification with 1-Lipschitz networks</i>.
    Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/10.15479/at-ista-19759">https://doi.org/10.15479/10.15479/at-ista-19759</a>
  chicago: Prach, Bernd. “Robust Image Classification with 1-Lipschitz Networks.”
    Institute of Science and Technology Austria, 2025. <a href="https://doi.org/10.15479/10.15479/at-ista-19759">https://doi.org/10.15479/10.15479/at-ista-19759</a>.
  ieee: B. Prach, “Robust image classification with 1-Lipschitz networks,” Institute
    of Science and Technology Austria, 2025.
  ista: Prach B. 2025. Robust image classification with 1-Lipschitz networks. Institute
    of Science and Technology Austria.
  mla: Prach, Bernd. <i>Robust Image Classification with 1-Lipschitz Networks</i>.
    Institute of Science and Technology Austria, 2025, doi:<a href="https://doi.org/10.15479/10.15479/at-ista-19759">10.15479/10.15479/at-ista-19759</a>.
  short: B. Prach, Robust Image Classification with 1-Lipschitz Networks, Institute
    of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-05-28T16:20:48Z
date_published: 2025-05-30T00:00:00Z
date_updated: 2026-04-07T11:49:52Z
day: '30'
ddc:
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degree_awarded: PhD
department:
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- _id: ChLa
doi: 10.15479/10.15479/at-ista-19759
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supervisor:
- first_name: Christoph
  full_name: Lampert, Christoph
  id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
  last_name: Lampert
  orcid: 0000-0001-8622-7887
title: Robust image classification with 1-Lipschitz networks
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2025'
...
