---
_id: '2023'
abstract:
- lang: eng
text: 'Understanding the evolution of dispersal is essential for understanding and
predicting the dynamics of natural populations. Two main factors are known to
influence dispersal evolution: spatio-temporal variation in the environment and
relatedness between individuals. However, the relation between these factors is
still poorly understood, and they are usually treated separately. In this article,
I present a theoretical framework that contains and connects effects of both environmental
variation and relatedness, and reproduces and extends their known features. Spatial
habitat variation selects for balanced dispersal strategies, whereby the population
is kept at an ideal free distribution. Within this class of dispersal strategies,
I explain how increased dispersal is promoted by perturbations to the dispersal
type frequencies. An explicit formula shows the magnitude of the selective advantage
of increased dispersal in terms of the spatial variability in the frequencies
of the different dispersal strategies present. These variances are capable of
capturing various sources of stochasticity and hence establish a common scale
for their effects on the evolution of dispersal. The results furthermore indicate
an alternative approach to identifying effects of relatedness on dispersal evolution.'
article_processing_charge: No
author:
- first_name: Sebastian
full_name: Novak, Sebastian
id: 461468AE-F248-11E8-B48F-1D18A9856A87
last_name: Novak
orcid: 0000-0002-2519-824X
citation:
ama: Novak S. Habitat heterogeneities versus spatial type frequency variances as
driving forces of dispersal evolution. Ecology and Evolution. 2014;4(24):4589-4597.
doi:10.1002/ece3.1289
apa: Novak, S. (2014). Habitat heterogeneities versus spatial type frequency variances
as driving forces of dispersal evolution. Ecology and Evolution. Wiley-Blackwell.
https://doi.org/10.1002/ece3.1289
chicago: Novak, Sebastian. “Habitat Heterogeneities versus Spatial Type Frequency
Variances as Driving Forces of Dispersal Evolution.” Ecology and Evolution.
Wiley-Blackwell, 2014. https://doi.org/10.1002/ece3.1289.
ieee: S. Novak, “Habitat heterogeneities versus spatial type frequency variances
as driving forces of dispersal evolution,” Ecology and Evolution, vol.
4, no. 24. Wiley-Blackwell, pp. 4589–4597, 2014.
ista: Novak S. 2014. Habitat heterogeneities versus spatial type frequency variances
as driving forces of dispersal evolution. Ecology and Evolution. 4(24), 4589–4597.
mla: Novak, Sebastian. “Habitat Heterogeneities versus Spatial Type Frequency Variances
as Driving Forces of Dispersal Evolution.” Ecology and Evolution, vol.
4, no. 24, Wiley-Blackwell, 2014, pp. 4589–97, doi:10.1002/ece3.1289.
short: S. Novak, Ecology and Evolution 4 (2014) 4589–4597.
corr_author: '1'
date_created: 2018-12-11T11:55:16Z
date_published: 2014-11-27T00:00:00Z
date_updated: 2026-07-29T11:27:43Z
day: '27'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1002/ece3.1289
ec_funded: 1
external_id:
isi:
- '000346736200003'
file:
- access_level: open_access
checksum: 9ab43db1b0fede7bfe560ed77e177b76
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:12:28Z
date_updated: 2020-07-14T12:45:25Z
file_id: '4946'
file_name: IST-2016-462-v1+1_Novak-2014-Ecology_and_Evolution.pdf
file_size: 118813
relation: main_file
file_date_updated: 2020-07-14T12:45:25Z
fulldoi: https://doi.org/10.1002/ece3.1289
has_accepted_license: '1'
intvolume: ' 4'
isi: 1
issue: '24'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '11'
oa: 1
oa_version: Published Version
page: 4589 - 4597
project:
- _id: 25B07788-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '250152'
name: Limits to selection in biology and in evolutionary computation
publication: Ecology and Evolution
publication_status: published
publisher: Wiley-Blackwell
publist_id: '5049'
pubrep_id: '462'
quality_controlled: '1'
related_material:
record:
- id: '1125'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Habitat heterogeneities versus spatial type frequency variances as driving
forces of dispersal evolution
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 4
year: '2014'
...
---
OA_place: publisher
OA_type: free access
_id: '22547'
abstract:
- lang: eng
text: Interannual variability of precipitation can influence components of the hydrological
budget, affecting them directly and indirectly through adjustments in vegetation
structure and function. We investigate the effects of fluctuations of annual precipitation
on ecohydrological dynamics. Specifically, we use the advanced weather generator,
AWE‐GEN, to simulate 200 years of hourly meteorological forcing obtained by imposing
four types of precipitation annual process with identical long‐term mean. The
generated time series force a mechanistic ecohydrological model, Tethys‐Chloris.
Simulations with perturbed precipitation variability are performed for four locations
characterized by different vegetation cover and climate. The results indicate
that long‐term transpiration (T) and evapotranspiration (ET) fluxes as well as
vegetation productivity expressed as Gross Primary Production (GPP) and Aboveground
Net Primary Production (ANPP) are essentially unaffected by the imposed climate
fluctuations. This finding supports the hypothesis of a relative insensitivity,
except for water‐limited environments, of interannual evapotranspiration and vegetation
productivity to annual climatic fluctuations, which are mostly reflected in the
fluxes of deep leakage and runoff. The occurrence of short periods of favorable
meteorological conditions randomly taking place within the year was found to be
a better explanatory variable for interannual variability of ET and ANPP than
average annual or growing season conditions. The results indicated that local,
single‐site sensitivities are considerably smaller than those observed across
climatic and vegetation spatial gradients and thus an important role of ecosystem
reorganization in modifying ANPP and ET sensitivity in a changing climate is recognized.
article_processing_charge: No
article_type: original
author:
- first_name: Simone
full_name: Fatichi, Simone
id: cf8e546b-a9b0-11f0-a43b-aa89ed1b56d6
last_name: Fatichi
- first_name: Valeriy Y.
full_name: Ivanov, Valeriy Y.
last_name: Ivanov
citation:
ama: Fatichi S, Ivanov VY. Interannual variability of evapotranspiration and vegetation
productivity. Water Resources Research. 2014;50(4):3275-3294. doi:10.1002/2013wr015044
apa: Fatichi, S., & Ivanov, V. Y. (2014). Interannual variability of evapotranspiration
and vegetation productivity. Water Resources Research. American Geophysical
Union. https://doi.org/10.1002/2013wr015044
chicago: Fatichi, Simone, and Valeriy Y. Ivanov. “Interannual Variability of Evapotranspiration
and Vegetation Productivity.” Water Resources Research. American Geophysical
Union, 2014. https://doi.org/10.1002/2013wr015044.
ieee: S. Fatichi and V. Y. Ivanov, “Interannual variability of evapotranspiration
and vegetation productivity,” Water Resources Research, vol. 50, no. 4.
American Geophysical Union, pp. 3275–3294, 2014.
ista: Fatichi S, Ivanov VY. 2014. Interannual variability of evapotranspiration
and vegetation productivity. Water Resources Research. 50(4), 3275–3294.
mla: Fatichi, Simone, and Valeriy Y. Ivanov. “Interannual Variability of Evapotranspiration
and Vegetation Productivity.” Water Resources Research, vol. 50, no. 4,
American Geophysical Union, 2014, pp. 3275–94, doi:10.1002/2013wr015044.
short: S. Fatichi, V.Y. Ivanov, Water Resources Research 50 (2014) 3275–3294.
das_tickbox: '1'
date_created: 2026-07-27T12:30:24Z
date_published: 2014-04-01T00:00:00Z
date_updated: 2026-08-06T08:11:01Z
day: '01'
doi: 10.1002/2013wr015044
extern: '1'
fulldoi: https://doi.org/10.1002/2013wr015044
intvolume: ' 50'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1002/2013WR015044
month: '04'
oa: 1
oa_version: Published Version
page: 3275-3294
publication: Water Resources Research
publication_identifier:
eissn:
- 1944-7973
issn:
- 0043-1397
publication_status: published
publisher: American Geophysical Union
quality_controlled: '1'
scopus_import: '1'
status: public
title: Interannual variability of evapotranspiration and vegetation productivity
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 50
year: '2014'
...
---
OA_place: publisher
OA_type: free access
_id: '22541'
article_processing_charge: No
article_type: letter_note
author:
- first_name: Simone
full_name: Fatichi, Simone
id: cf8e546b-a9b0-11f0-a43b-aa89ed1b56d6
last_name: Fatichi
- first_name: Sebastian
full_name: Leuzinger, Sebastian
last_name: Leuzinger
- first_name: Christian
full_name: Körner, Christian
last_name: Körner
citation:
ama: 'Fatichi S, Leuzinger S, Körner C. Moving beyond photosynthesis: from carbon
source to sink‐driven vegetation modeling. New Phytologist. 2014;201(4):1086-1095.
doi:10.1111/nph.12614'
apa: 'Fatichi, S., Leuzinger, S., & Körner, C. (2014). Moving beyond photosynthesis:
from carbon source to sink‐driven vegetation modeling. New Phytologist.
Wiley. https://doi.org/10.1111/nph.12614'
chicago: 'Fatichi, Simone, Sebastian Leuzinger, and Christian Körner. “Moving beyond
Photosynthesis: From Carbon Source to Sink‐driven Vegetation Modeling.” New
Phytologist. Wiley, 2014. https://doi.org/10.1111/nph.12614.'
ieee: 'S. Fatichi, S. Leuzinger, and C. Körner, “Moving beyond photosynthesis: from
carbon source to sink‐driven vegetation modeling,” New Phytologist, vol.
201, no. 4. Wiley, pp. 1086–1095, 2014.'
ista: 'Fatichi S, Leuzinger S, Körner C. 2014. Moving beyond photosynthesis: from
carbon source to sink‐driven vegetation modeling. New Phytologist. 201(4), 1086–1095.'
mla: 'Fatichi, Simone, et al. “Moving beyond Photosynthesis: From Carbon Source
to Sink‐driven Vegetation Modeling.” New Phytologist, vol. 201, no. 4,
Wiley, 2014, pp. 1086–95, doi:10.1111/nph.12614.'
short: S. Fatichi, S. Leuzinger, C. Körner, New Phytologist 201 (2014) 1086–1095.
das_tickbox: '1'
date_created: 2026-07-27T12:30:24Z
date_published: 2014-03-01T00:00:00Z
date_updated: 2026-08-06T08:12:29Z
day: '01'
doi: 10.1111/nph.12614
extern: '1'
external_id:
pmid:
- '24261587'
fulldoi: https://doi.org/10.1111/nph.12614
intvolume: ' 201'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1111/nph.12614
month: '03'
oa: 1
oa_version: Published Version
page: 1086-1095
pmid: 1
publication: New Phytologist
publication_identifier:
eissn:
- 1469-8137
issn:
- 0028-646X
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Moving beyond photosynthesis: from carbon source to sink‐driven vegetation
modeling'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 201
year: '2014'
...
---
OA_type: closed access
_id: '22545'
abstract:
- lang: eng
text: Climate change represents a major increase in uncertainty that water managers
and policy makers will need to integrate into water resources policy and management.
A certain level of uncertainty has always existed in water resources planning,
but the speed and intensity of changes in baseline conditions that climate change
embodies might require a shift in perspective. This article draws on both the
social and physical science results of the EU-FP7 ACQWA project to better understand
the challenges and opportunities for adaptation to climate change impacts on the
hydrology of the upper Rhone basin in the Canton Valais, Switzerland. It first
presents the results of hydro-climatic change projections downscaled to more temporally
and spatially-relevant frames of reference for decision makers. Then, it analyses
the current policy and legislative framework within which these changes will take
place, according to the policy coherence across different water-relevant frameworks
as well as the integration and mainstreaming of climate change. It compares the
current policy and legislative frameworks for different aspects of water resources
management to the projected impacts of climate change on the hydrology of the
upper Rhone basin, in order to examine the appropriateness of the current approach
for responding to a changing climatic context. Significant uncertainties pose
numerous challenges in the governance context. The study draws on adaptive governance
principles, to propose policy actions across different scales of governance to
better manage baseline variability as well as more ‘unpredictable’ uncertainty
from climate change impacts.
article_processing_charge: No
article_type: original
author:
- first_name: Margot Hill
full_name: Clarvis, Margot Hill
last_name: Clarvis
- first_name: Simone
full_name: Fatichi, Simone
id: cf8e546b-a9b0-11f0-a43b-aa89ed1b56d6
last_name: Fatichi
- first_name: Andrew
full_name: Allan, Andrew
last_name: Allan
- first_name: Jürg
full_name: Fuhrer, Jürg
last_name: Fuhrer
- first_name: Markus
full_name: Stoffel, Markus
last_name: Stoffel
- first_name: Franco
full_name: Romerio, Franco
last_name: Romerio
- first_name: Ludovic
full_name: Gaudard, Ludovic
last_name: Gaudard
- first_name: Paolo
full_name: Burlando, Paolo
last_name: Burlando
- first_name: Martin
full_name: Beniston, Martin
last_name: Beniston
- first_name: Elena
full_name: Xoplaki, Elena
last_name: Xoplaki
- first_name: Andrea
full_name: Toreti, Andrea
last_name: Toreti
citation:
ama: 'Clarvis MH, Fatichi S, Allan A, et al. Governing and managing water resources
under changing hydro-climatic contexts: The case of the upper Rhone basin. Environmental
Science & Policy. 2014;43:56-67. doi:10.1016/j.envsci.2013.11.005'
apa: 'Clarvis, M. H., Fatichi, S., Allan, A., Fuhrer, J., Stoffel, M., Romerio,
F., … Toreti, A. (2014). Governing and managing water resources under changing
hydro-climatic contexts: The case of the upper Rhone basin. Environmental Science
& Policy. Elsevier. https://doi.org/10.1016/j.envsci.2013.11.005'
chicago: 'Clarvis, Margot Hill, Simone Fatichi, Andrew Allan, Jürg Fuhrer, Markus
Stoffel, Franco Romerio, Ludovic Gaudard, et al. “Governing and Managing Water
Resources under Changing Hydro-Climatic Contexts: The Case of the Upper Rhone
Basin.” Environmental Science & Policy. Elsevier, 2014. https://doi.org/10.1016/j.envsci.2013.11.005.'
ieee: 'M. H. Clarvis et al., “Governing and managing water resources under
changing hydro-climatic contexts: The case of the upper Rhone basin,” Environmental
Science & Policy, vol. 43. Elsevier, pp. 56–67, 2014.'
ista: 'Clarvis MH, Fatichi S, Allan A, Fuhrer J, Stoffel M, Romerio F, Gaudard L,
Burlando P, Beniston M, Xoplaki E, Toreti A. 2014. Governing and managing water
resources under changing hydro-climatic contexts: The case of the upper Rhone
basin. Environmental Science & Policy. 43, 56–67.'
mla: 'Clarvis, Margot Hill, et al. “Governing and Managing Water Resources under
Changing Hydro-Climatic Contexts: The Case of the Upper Rhone Basin.” Environmental
Science & Policy, vol. 43, Elsevier, 2014, pp. 56–67, doi:10.1016/j.envsci.2013.11.005.'
short: M.H. Clarvis, S. Fatichi, A. Allan, J. Fuhrer, M. Stoffel, F. Romerio, L.
Gaudard, P. Burlando, M. Beniston, E. Xoplaki, A. Toreti, Environmental Science
& Policy 43 (2014) 56–67.
das_tickbox: '1'
date_created: 2026-07-27T12:30:24Z
date_published: 2014-11-01T00:00:00Z
date_updated: 2026-08-06T08:21:08Z
day: '01'
doi: 10.1016/j.envsci.2013.11.005
extern: '1'
fulldoi: https://doi.org/10.1016/j.envsci.2013.11.005
intvolume: ' 43'
keyword:
- Climate change impacts
- Adaptation
- Water governance
- Water management
- Rhone basin
- Switzerland
language:
- iso: eng
month: '11'
oa_version: None
page: 56-67
publication: Environmental Science & Policy
publication_identifier:
eissn:
- 1873-6416
issn:
- 1462-9011
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Governing and managing water resources under changing hydro-climatic contexts:
The case of the upper Rhone basin'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 43
year: '2014'
...
---
OA_place: publisher
OA_type: free access
_id: '22560'
abstract:
- lang: eng
text: Grassland and pastures are important land uses in subalpine and alpine environments.
They are typically subjected to management practices that can change the biophysical
structure of the canopy through defoliation and can alter soil hydraulic properties.
These modifications have the potential to impact hydrological and energy fluxes
as well as the primary productivity of grasslands. We investigate how a series
of management practices, such as grass cut, grazing, and the consequent soil compaction
due to treading by animals are affecting water resources, flood generation, and
grassland productivity in a subalpine region. Results are obtained using a mechanistic
ecohydrological model, Tethys-Chloris. The model is first confirmed using energy,
water, and carbon fluxes measured at three eddy covariance stations over grasslands
in Switzerland and discharge measured in a small experimental catchment. A series
of virtual experiments are then designed to elucidate the importance of various
management scenarios at the plot and catchment scales. Results show that only
severe management actions such as low grass cuts or heavy grazing are able to
influence considerably the long-term hydrological behavior. Moderate management
practices are typically unable to modify the system response in terms of energy
and water fluxes. An important short-term effect is represented by animal-induced
soil compaction that can reduce infiltration capacity leading to peak flow considerably
higher than in undisturbed conditions. The productivity of vegetation in absence
of nutrient limitation is considerably affected by the different management scenarios
with tolerable disturbances that lead to higher aboveground net primary production.
article_processing_charge: No
article_type: original
author:
- first_name: Simone
full_name: Fatichi, Simone
id: cf8e546b-a9b0-11f0-a43b-aa89ed1b56d6
last_name: Fatichi
- first_name: Matthias J.
full_name: Zeeman, Matthias J.
last_name: Zeeman
- first_name: Jürg
full_name: Fuhrer, Jürg
last_name: Fuhrer
- first_name: Paolo
full_name: Burlando, Paolo
last_name: Burlando
citation:
ama: 'Fatichi S, Zeeman MJ, Fuhrer J, Burlando P. Ecohydrological effects of management
on subalpine grasslands: From local to catchment scale. Water Resources Research.
2014;50(1):148-164. doi:10.1002/2013wr014535'
apa: 'Fatichi, S., Zeeman, M. J., Fuhrer, J., & Burlando, P. (2014). Ecohydrological
effects of management on subalpine grasslands: From local to catchment scale.
Water Resources Research. American Geophysical Union. https://doi.org/10.1002/2013wr014535'
chicago: 'Fatichi, Simone, Matthias J. Zeeman, Jürg Fuhrer, and Paolo Burlando.
“Ecohydrological Effects of Management on Subalpine Grasslands: From Local to
Catchment Scale.” Water Resources Research. American Geophysical Union,
2014. https://doi.org/10.1002/2013wr014535.'
ieee: 'S. Fatichi, M. J. Zeeman, J. Fuhrer, and P. Burlando, “Ecohydrological effects
of management on subalpine grasslands: From local to catchment scale,” Water
Resources Research, vol. 50, no. 1. American Geophysical Union, pp. 148–164,
2014.'
ista: 'Fatichi S, Zeeman MJ, Fuhrer J, Burlando P. 2014. Ecohydrological effects
of management on subalpine grasslands: From local to catchment scale. Water Resources
Research. 50(1), 148–164.'
mla: 'Fatichi, Simone, et al. “Ecohydrological Effects of Management on Subalpine
Grasslands: From Local to Catchment Scale.” Water Resources Research, vol.
50, no. 1, American Geophysical Union, 2014, pp. 148–64, doi:10.1002/2013wr014535.'
short: S. Fatichi, M.J. Zeeman, J. Fuhrer, P. Burlando, Water Resources Research
50 (2014) 148–164.
das_tickbox: '1'
date_created: 2026-07-27T12:30:24Z
date_published: 2014-01-01T00:00:00Z
date_updated: 2026-08-06T09:48:24Z
day: '01'
doi: 10.1002/2013wr014535
extern: '1'
fulldoi: https://doi.org/10.1002/2013wr014535
intvolume: ' 50'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1002/2013WR014535
month: '01'
oa: 1
oa_version: Published Version
page: 148-164
publication: Water Resources Research
publication_identifier:
eissn:
- 1944-7973
issn:
- 0043-1397
publication_status: published
publisher: American Geophysical Union
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Ecohydrological effects of management on subalpine grasslands: From local
to catchment scale'
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 50
year: '2014'
...
---
OA_type: closed access
_id: '22577'
abstract:
- lang: eng
text: The spatio-temporal variability of rainfall, especially at fine temporal and
spatial scales can significantly affect flood generation, leading to a large variability
in the flood response and uncertainty in its prediction. In this study we quantify
the impact of rainfall spatial and temporal structure on the catchment hydrological
response based on a numerical experiment. Rainfall ensembles generated using a
state-of-the-art space–time stochastic model are used as input into a distributed
process-based hydrological model. The sensitivity of the hydrograph to several
structural characteristics of storm rainfall for three soil moisture initial conditions
is numerically assessed at the basin outlet of an Alpine catchment in central
Switzerland. The results highlight that the flood response is strongly affected
by the temporal correlation of rainfall and to a lesser extent by its spatial
variability. Initial soil moisture conditions play a paramount role in mediating
the response. We identify the underlying mechanistic explanations in terms of
runoff generation and connectivity of saturated areas that determine the sensitivity
of flood response to the spatio-temporal variability of rainfall. We show that
the element that mostly influences both the flood peak and the time of peak occurrence
is the clustering of saturated areas in the catchment which leads to local enhanced
runoff.
article_processing_charge: No
article_type: original
author:
- first_name: Athanasios
full_name: Paschalis, Athanasios
last_name: Paschalis
- first_name: Simone
full_name: Fatichi, Simone
id: cf8e546b-a9b0-11f0-a43b-aa89ed1b56d6
last_name: Fatichi
- first_name: Peter
full_name: Molnar, Peter
last_name: Molnar
- first_name: Stefan
full_name: Rimkus, Stefan
last_name: Rimkus
- first_name: Paolo
full_name: Burlando, Paolo
last_name: Burlando
citation:
ama: Paschalis A, Fatichi S, Molnar P, Rimkus S, Burlando P. On the effects of small
scale space–time variability of rainfall on basin flood response. Journal of
Hydrology. 2014;514:313-327. doi:10.1016/j.jhydrol.2014.04.014
apa: Paschalis, A., Fatichi, S., Molnar, P., Rimkus, S., & Burlando, P. (2014).
On the effects of small scale space–time variability of rainfall on basin flood
response. Journal of Hydrology. Elsevier. https://doi.org/10.1016/j.jhydrol.2014.04.014
chicago: Paschalis, Athanasios, Simone Fatichi, Peter Molnar, Stefan Rimkus, and
Paolo Burlando. “On the Effects of Small Scale Space–Time Variability of Rainfall
on Basin Flood Response.” Journal of Hydrology. Elsevier, 2014. https://doi.org/10.1016/j.jhydrol.2014.04.014.
ieee: A. Paschalis, S. Fatichi, P. Molnar, S. Rimkus, and P. Burlando, “On the effects
of small scale space–time variability of rainfall on basin flood response,” Journal
of Hydrology, vol. 514. Elsevier, pp. 313–327, 2014.
ista: Paschalis A, Fatichi S, Molnar P, Rimkus S, Burlando P. 2014. On the effects
of small scale space–time variability of rainfall on basin flood response. Journal
of Hydrology. 514, 313–327.
mla: Paschalis, Athanasios, et al. “On the Effects of Small Scale Space–Time Variability
of Rainfall on Basin Flood Response.” Journal of Hydrology, vol. 514, Elsevier,
2014, pp. 313–27, doi:10.1016/j.jhydrol.2014.04.014.
short: A. Paschalis, S. Fatichi, P. Molnar, S. Rimkus, P. Burlando, Journal of Hydrology
514 (2014) 313–327.
das_tickbox: '1'
date_created: 2026-07-27T12:30:25Z
date_published: 2014-06-06T00:00:00Z
date_updated: 2026-08-10T12:09:26Z
day: '06'
doi: 10.1016/j.jhydrol.2014.04.014
extern: '1'
fulldoi: https://doi.org/10.1016/j.jhydrol.2014.04.014
intvolume: ' 514'
keyword:
- Flood response
- Hydrological modeling
- Stochastic rainfall modeling
- STREAP
language:
- iso: eng
month: '06'
oa_version: None
page: 313-327
publication: Journal of Hydrology
publication_identifier:
eissn:
- 1879-2707
issn:
- 0022-1694
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: On the effects of small scale space–time variability of rainfall on basin flood
response
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 514
year: '2014'
...
---
OA_type: closed access
_id: '22575'
abstract:
- lang: eng
text: We analyze the performance of composite stochastic models of temporal precipitation
which can satisfactorily reproduce precipitation properties across a wide range
of temporal scales. The rationale is that a combination of stochastic precipitation
models which are most appropriate for specific limited temporal scales leads to
better overall performance across a wider range of scales than single models alone.
We investigate different model combinations. For the coarse (daily) scale these
are models based on Alternating renewal processes, Markov chains, and Poisson
cluster models, which are then combined with a microcanonical Multiplicative Random
Cascade model to disaggregate precipitation to finer (minute) scales. The composite
models were tested on data at four sites in different climates. The results show
that model combinations improve the performance in key statistics such as probability
distributions of precipitation depth, autocorrelation structure, intermittency,
reproduction of extremes, compared to single models. At the same time they remain
reasonably parsimonious. No model combination was found to outperform the others
at all sites and for all statistics, however we provide insight on the capabilities
of specific model combinations. The results for the four different climates are
similar, which suggests a degree of generality and wider applicability of the
approach.
article_processing_charge: No
article_type: original
author:
- first_name: Athanasios
full_name: Paschalis, Athanasios
last_name: Paschalis
- first_name: Peter
full_name: Molnar, Peter
last_name: Molnar
- first_name: Simone
full_name: Fatichi, Simone
id: cf8e546b-a9b0-11f0-a43b-aa89ed1b56d6
last_name: Fatichi
- first_name: Paolo
full_name: Burlando, Paolo
last_name: Burlando
citation:
ama: Paschalis A, Molnar P, Fatichi S, Burlando P. On temporal stochastic modeling
of precipitation, nesting models across scales. Advances in Water Resources.
2014;63:152-166. doi:10.1016/j.advwatres.2013.11.006
apa: Paschalis, A., Molnar, P., Fatichi, S., & Burlando, P. (2014). On temporal
stochastic modeling of precipitation, nesting models across scales. Advances
in Water Resources. Elsevier. https://doi.org/10.1016/j.advwatres.2013.11.006
chicago: Paschalis, Athanasios, Peter Molnar, Simone Fatichi, and Paolo Burlando.
“On Temporal Stochastic Modeling of Precipitation, Nesting Models across Scales.”
Advances in Water Resources. Elsevier, 2014. https://doi.org/10.1016/j.advwatres.2013.11.006.
ieee: A. Paschalis, P. Molnar, S. Fatichi, and P. Burlando, “On temporal stochastic
modeling of precipitation, nesting models across scales,” Advances in Water
Resources, vol. 63. Elsevier, pp. 152–166, 2014.
ista: Paschalis A, Molnar P, Fatichi S, Burlando P. 2014. On temporal stochastic
modeling of precipitation, nesting models across scales. Advances in Water Resources.
63, 152–166.
mla: Paschalis, Athanasios, et al. “On Temporal Stochastic Modeling of Precipitation,
Nesting Models across Scales.” Advances in Water Resources, vol. 63, Elsevier,
2014, pp. 152–66, doi:10.1016/j.advwatres.2013.11.006.
short: A. Paschalis, P. Molnar, S. Fatichi, P. Burlando, Advances in Water Resources
63 (2014) 152–166.
das_tickbox: '1'
date_created: 2026-07-27T12:30:25Z
date_published: 2014-01-01T00:00:00Z
date_updated: 2026-08-10T11:55:17Z
day: '01'
doi: 10.1016/j.advwatres.2013.11.006
extern: '1'
fulldoi: https://doi.org/10.1016/j.advwatres.2013.11.006
intvolume: ' 63'
keyword:
- Stochastic rainfall models
- Poisson cluster model
- Multiplicative Random Cascade
- Markov chain
- Alternating renewal process
language:
- iso: eng
month: '01'
oa_version: None
page: 152-166
publication: Advances in Water Resources
publication_identifier:
issn:
- 0309-1708
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: On temporal stochastic modeling of precipitation, nesting models across scales
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 63
year: '2014'
...
---
_id: '2036'
abstract:
- lang: eng
text: ' In rapidly changing environments, selection history may impact the dynamics
of adaptation. Mutations selected in one environment may result in pleiotropic
fitness trade-offs in subsequent novel environments, slowing the rates of adaptation.
Epistatic interactions between mutations selected in sequential stressful environments
may slow or accelerate subsequent rates of adaptation, depending on the nature
of that interaction. We explored the dynamics of adaptation during sequential
exposure to herbicides with different modes of action in Chlamydomonas reinhardtii.
Evolution of resistance to two of the herbicides was largely independent of selection
history. For carbetamide, previous adaptation to other herbicide modes of action
positively impacted the likelihood of adaptation to this herbicide. Furthermore,
while adaptation to all individual herbicides was associated with pleiotropic
fitness costs in stress-free environments, we observed that accumulation of resistance
mechanisms was accompanied by a reduction in overall fitness costs. We suggest
that antagonistic epistasis may be a driving mechanism that enables populations
to more readily adapt in novel environments. These findings highlight the potential
for sequences of xenobiotics to facilitate the rapid evolution of multiple-drug
and -pesticide resistance, as well as the potential for epistatic interactions
between adaptive mutations to facilitate evolutionary rescue in rapidly changing
environments. '
acknowledgement: The project was supported by Leverhulme Trust.
article_number: '20141679'
article_processing_charge: No
author:
- first_name: Mato
full_name: Lagator, Mato
id: 345D25EC-F248-11E8-B48F-1D18A9856A87
last_name: Lagator
- first_name: Nick
full_name: Colegrave, Nick
last_name: Colegrave
- first_name: Paul
full_name: Neve, Paul
last_name: Neve
citation:
ama: Lagator M, Colegrave N, Neve P. Selection history and epistatic interactions
impact dynamics of adaptation to novel environmental stresses. Proceedings
of the Royal Society of London Series B Biological Sciences. 2014;281(1794).
doi:10.1098/rspb.2014.1679
apa: Lagator, M., Colegrave, N., & Neve, P. (2014). Selection history and epistatic
interactions impact dynamics of adaptation to novel environmental stresses. Proceedings
of the Royal Society of London Series B Biological Sciences. Royal Society.
https://doi.org/10.1098/rspb.2014.1679
chicago: Lagator, Mato, Nick Colegrave, and Paul Neve. “Selection History and Epistatic
Interactions Impact Dynamics of Adaptation to Novel Environmental Stresses.” Proceedings
of the Royal Society of London Series B Biological Sciences. Royal Society,
2014. https://doi.org/10.1098/rspb.2014.1679.
ieee: M. Lagator, N. Colegrave, and P. Neve, “Selection history and epistatic interactions
impact dynamics of adaptation to novel environmental stresses,” Proceedings
of the Royal Society of London Series B Biological Sciences, vol. 281, no.
1794. Royal Society, 2014.
ista: Lagator M, Colegrave N, Neve P. 2014. Selection history and epistatic interactions
impact dynamics of adaptation to novel environmental stresses. Proceedings of
the Royal Society of London Series B Biological Sciences. 281(1794), 20141679.
mla: Lagator, Mato, et al. “Selection History and Epistatic Interactions Impact
Dynamics of Adaptation to Novel Environmental Stresses.” Proceedings of the
Royal Society of London Series B Biological Sciences, vol. 281, no. 1794,
20141679, Royal Society, 2014, doi:10.1098/rspb.2014.1679.
short: M. Lagator, N. Colegrave, P. Neve, Proceedings of the Royal Society of London
Series B Biological Sciences 281 (2014).
date_created: 2018-12-11T11:55:21Z
date_published: 2014-09-17T00:00:00Z
date_updated: 2026-08-12T06:26:10Z
day: '17'
department:
- _id: CaGu
doi: 10.1098/rspb.2014.1679
external_id:
isi:
- '000341922700009'
fulldoi: https://doi.org/10.1098/rspb.2014.1679
intvolume: ' 281'
isi: 1
issue: '1794'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211454/
month: '09'
oa: 1
oa_version: Submitted Version
publication: Proceedings of the Royal Society of London Series B Biological Sciences
publication_status: published
publisher: Royal Society
publist_id: '5019'
quality_controlled: '1'
related_material:
record:
- id: '9741'
relation: research_data
status: public
scopus_import: '1'
status: public
title: Selection history and epistatic interactions impact dynamics of adaptation
to novel environmental stresses
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 281
year: '2014'
...
---
_id: '9741'
abstract:
- lang: eng
text: In rapidly changing environments, selection history may impact the dynamics
of adaptation. Mutations selected in one environment may result in pleiotropic
fitness trade-offs in subsequent novel environments, slowing the rates of adaptation.
Epistatic interactions between mutations selected in sequential stressful environments
may slow or accelerate subsequent rates of adaptation, depending on the nature
of that interaction. We explored the dynamics of adaptation during sequential
exposure to herbicides with different modes of action in Chlamydomonas reinhardtii.
Evolution of resistance to two of the herbicides was largely independent of selection
history. For carbetamide, previous adaptation to other herbicide modes of action
positively impacted the likelihood of adaptation to this herbicide. Furthermore,
while adaptation to all individual herbicides was associated with pleiotropic
fitness costs in stress-free environments, we observed that accumulation of resistance
mechanisms was accompanied by a reduction in overall fitness costs. We suggest
that antagonistic epistasis may be a driving mechanism that enables populations
to more readily adapt in novel environments. These findings highlight the potential
for sequences of xenobiotics to facilitate the rapid evolution of multiple-drug
and -pesticide resistance, as well as the potential for epistatic interactions
between adaptive mutations to facilitate evolutionary rescue in rapidly changing
environments.
article_processing_charge: No
author:
- first_name: Mato
full_name: Lagator, Mato
id: 345D25EC-F248-11E8-B48F-1D18A9856A87
last_name: Lagator
- first_name: Nick
full_name: Colegrave, Nick
last_name: Colegrave
- first_name: Paul
full_name: Neve, Paul
last_name: Neve
citation:
ama: 'Lagator M, Colegrave N, Neve P. Data from: Selection history and epistatic
interactions impact dynamics of adaptation to novel environmental stresses. 2014.
doi:10.5061/dryad.85dn7'
apa: 'Lagator, M., Colegrave, N., & Neve, P. (2014). Data from: Selection history
and epistatic interactions impact dynamics of adaptation to novel environmental
stresses. Dryad. https://doi.org/10.5061/dryad.85dn7'
chicago: 'Lagator, Mato, Nick Colegrave, and Paul Neve. “Data from: Selection History
and Epistatic Interactions Impact Dynamics of Adaptation to Novel Environmental
Stresses.” Dryad, 2014. https://doi.org/10.5061/dryad.85dn7.'
ieee: 'M. Lagator, N. Colegrave, and P. Neve, “Data from: Selection history and
epistatic interactions impact dynamics of adaptation to novel environmental stresses.”
Dryad, 2014.'
ista: 'Lagator M, Colegrave N, Neve P. 2014. Data from: Selection history and epistatic
interactions impact dynamics of adaptation to novel environmental stresses, Dryad,
10.5061/dryad.85dn7.'
mla: 'Lagator, Mato, et al. Data from: Selection History and Epistatic Interactions
Impact Dynamics of Adaptation to Novel Environmental Stresses. Dryad, 2014,
doi:10.5061/dryad.85dn7.'
short: M. Lagator, N. Colegrave, P. Neve, (2014).
date_created: 2021-07-28T08:48:06Z
date_published: 2014-08-21T00:00:00Z
date_updated: 2026-08-12T06:26:09Z
day: '21'
department:
- _id: CaGu
doi: 10.5061/dryad.85dn7
fulldoi: https://doi.org/10.5061/dryad.85dn7
main_file_link:
- open_access: '1'
url: https://doi.org/10.5061/dryad.85dn7
month: '08'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
record:
- id: '2036'
relation: used_in_publication
status: public
status: public
title: 'Data from: Selection history and epistatic interactions impact dynamics of
adaptation to novel environmental stresses'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2014'
...
---
_id: '2251'
abstract:
- lang: eng
text: 'Sharp wave/ripple (SWR, 150–250 Hz) hippocampal events have long been postulated
to be involved in memory consolidation. However, more recent work has investigated
SWRs that occur during active waking behaviour: findings that suggest that SWRs
may also play a role in cell assembly strengthening or spatial working memory.
Do such theories of SWR function apply to animal learning? This review discusses
how general theories linking SWRs to memory-related function may explain circuit
mechanisms related to rodent spatial learning and to the associated stabilization
of new cognitive maps.'
article_number: '20120528'
article_processing_charge: No
author:
- first_name: Jozsef L
full_name: Csicsvari, Jozsef L
id: 3FA14672-F248-11E8-B48F-1D18A9856A87
last_name: Csicsvari
orcid: 0000-0002-5193-4036
- first_name: David
full_name: Dupret, David
last_name: Dupret
citation:
ama: Csicsvari JL, Dupret D. Sharp wave/ripple network oscillations and learning-associated
hippocampal maps. Philosophical Transactions of the Royal Society of London
Series B, Biological Sciences. 2014;369(1635). doi:10.1098/rstb.2012.0528
apa: Csicsvari, J. L., & Dupret, D. (2014). Sharp wave/ripple network oscillations
and learning-associated hippocampal maps. Philosophical Transactions of the
Royal Society of London. Series B, Biological Sciences. Royal Society. https://doi.org/10.1098/rstb.2012.0528
chicago: Csicsvari, Jozsef L, and David Dupret. “Sharp Wave/Ripple Network Oscillations
and Learning-Associated Hippocampal Maps.” Philosophical Transactions of the
Royal Society of London. Series B, Biological Sciences. Royal Society, 2014.
https://doi.org/10.1098/rstb.2012.0528.
ieee: J. L. Csicsvari and D. Dupret, “Sharp wave/ripple network oscillations and
learning-associated hippocampal maps,” Philosophical Transactions of the Royal
Society of London. Series B, Biological Sciences, vol. 369, no. 1635. Royal
Society, 2014.
ista: Csicsvari JL, Dupret D. 2014. Sharp wave/ripple network oscillations and learning-associated
hippocampal maps. Philosophical Transactions of the Royal Society of London. Series
B, Biological Sciences. 369(1635), 20120528.
mla: Csicsvari, Jozsef L., and David Dupret. “Sharp Wave/Ripple Network Oscillations
and Learning-Associated Hippocampal Maps.” Philosophical Transactions of the
Royal Society of London. Series B, Biological Sciences, vol. 369, no. 1635,
20120528, Royal Society, 2014, doi:10.1098/rstb.2012.0528.
short: J.L. Csicsvari, D. Dupret, Philosophical Transactions of the Royal Society
of London. Series B, Biological Sciences 369 (2014).
corr_author: '1'
das_tickbox: '1'
date_created: 2018-12-11T11:56:34Z
date_published: 2014-02-05T00:00:00Z
date_updated: 2026-08-12T06:27:15Z
day: '05'
ddc:
- '570'
department:
- _id: JoCs
doi: 10.1098/rstb.2012.0528
external_id:
isi:
- '000332465300014'
pmid:
- '24366138'
file:
- access_level: open_access
checksum: 51beb33de71c9c19e0c205a20d206f9a
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:13:24Z
date_updated: 2020-07-14T12:45:34Z
file_id: '5006'
file_name: IST-2016-527-v1+1_20120528.full.pdf
file_size: 771896
relation: main_file
file_date_updated: 2020-07-14T12:45:34Z
fulldoi: https://doi.org/10.1098/rstb.2012.0528
has_accepted_license: '1'
intvolume: ' 369'
isi: 1
issue: '1635'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/3.0/
month: '02'
oa: 1
oa_version: Published Version
pmid: 1
publication: Philosophical Transactions of the Royal Society of London. Series B,
Biological Sciences
publication_identifier:
issn:
- 0962-8436
publication_status: published
publisher: Royal Society
publist_id: '4697'
pubrep_id: '527'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Sharp wave/ripple network oscillations and learning-associated hippocampal
maps
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/3.0/legalcode
name: Creative Commons Attribution 3.0 Unported (CC BY 3.0)
short: CC BY (3.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 369
year: '2014'
...
---
_id: '1821'
abstract:
- lang: eng
text: We review recent progress towards a rigorous understanding of the Bogoliubov
approximation for bosonic quantum many-body systems. We focus, in particular,
on the excitation spectrum of a Bose gas in the mean-field (Hartree) limit. A
list of open problems will be discussed at the end.
article_number: '1.4881536'
article_processing_charge: No
author:
- first_name: Robert
full_name: Seiringer, Robert
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: Seiringer R. Bose gases, Bose-Einstein condensation, and the Bogoliubov approximation.
Journal of Mathematical Physics. 2014;55(7). doi:10.1063/1.4881536
apa: Seiringer, R. (2014). Bose gases, Bose-Einstein condensation, and the Bogoliubov
approximation. Journal of Mathematical Physics. AIP Publishing. https://doi.org/10.1063/1.4881536
chicago: Seiringer, Robert. “Bose Gases, Bose-Einstein Condensation, and the Bogoliubov
Approximation.” Journal of Mathematical Physics. AIP Publishing, 2014.
https://doi.org/10.1063/1.4881536.
ieee: R. Seiringer, “Bose gases, Bose-Einstein condensation, and the Bogoliubov
approximation,” Journal of Mathematical Physics, vol. 55, no. 7. AIP Publishing,
2014.
ista: Seiringer R. 2014. Bose gases, Bose-Einstein condensation, and the Bogoliubov
approximation. Journal of Mathematical Physics. 55(7), 1.4881536.
mla: Seiringer, Robert. “Bose Gases, Bose-Einstein Condensation, and the Bogoliubov
Approximation.” Journal of Mathematical Physics, vol. 55, no. 7, 1.4881536,
AIP Publishing, 2014, doi:10.1063/1.4881536.
short: R. Seiringer, Journal of Mathematical Physics 55 (2014).
corr_author: '1'
date_created: 2018-12-11T11:54:11Z
date_published: 2014-06-26T00:00:00Z
date_updated: 2026-08-12T13:58:01Z
day: '26'
ddc:
- '510'
- '530'
department:
- _id: RoSe
doi: 10.1063/1.4881536
external_id:
isi:
- '000341174600010'
file:
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checksum: ed0efc93c10f1341155f0316af617b82
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:15:49Z
date_updated: 2020-07-14T12:45:17Z
file_id: '5172'
file_name: IST-2016-532-v1+1_J._Mathematical_Phys._2014_Seiringer.pdf
file_size: 269171
relation: main_file
file_date_updated: 2020-07-14T12:45:17Z
fulldoi: https://doi.org/10.1063/1.4881536
has_accepted_license: '1'
intvolume: ' 55'
isi: 1
issue: '7'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Submitted Version
project:
- _id: 26450934-B435-11E9-9278-68D0E5697425
name: NSERC Postdoctoral fellowship
publication: Journal of Mathematical Physics
publication_status: published
publisher: AIP Publishing
publist_id: '5285'
pubrep_id: '532'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Bose gases, Bose-Einstein condensation, and the Bogoliubov approximation
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 55
year: '2014'
...
---
_id: '1822'
article_number: '075101'
article_processing_charge: No
author:
- first_name: Vojkan
full_name: Jakšić, Vojkan
last_name: Jakšić
- first_name: Claude
full_name: Pillet, Claude
last_name: Pillet
- first_name: Robert
full_name: Seiringer, Robert
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: Jakšić V, Pillet C, Seiringer R. Introduction. Journal of Mathematical Physics.
2014;55(7). doi:10.1063/1.4884877
apa: Jakšić, V., Pillet, C., & Seiringer, R. (2014). Introduction. Journal
of Mathematical Physics. AIP Publishing. https://doi.org/10.1063/1.4884877
chicago: Jakšić, Vojkan, Claude Pillet, and Robert Seiringer. “Introduction.” Journal
of Mathematical Physics. AIP Publishing, 2014. https://doi.org/10.1063/1.4884877.
ieee: V. Jakšić, C. Pillet, and R. Seiringer, “Introduction,” Journal of Mathematical
Physics, vol. 55, no. 7. AIP Publishing, 2014.
ista: Jakšić V, Pillet C, Seiringer R. 2014. Introduction. Journal of Mathematical
Physics. 55(7), 075101.
mla: Jakšić, Vojkan, et al. “Introduction.” Journal of Mathematical Physics,
vol. 55, no. 7, 075101, AIP Publishing, 2014, doi:10.1063/1.4884877.
short: V. Jakšić, C. Pillet, R. Seiringer, Journal of Mathematical Physics 55 (2014).
date_created: 2018-12-11T11:54:12Z
date_published: 2014-07-01T00:00:00Z
date_updated: 2026-08-12T13:58:20Z
day: '01'
department:
- _id: RoSe
doi: 10.1063/1.4884877
external_id:
isi:
- '000341174600001'
fulldoi: https://doi.org/10.1063/1.4884877
intvolume: ' 55'
isi: 1
issue: '7'
language:
- iso: eng
month: '07'
oa_version: None
publication: Journal of Mathematical Physics
publication_status: published
publisher: AIP Publishing
publist_id: '5284'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Introduction
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 55
year: '2014'
...
---
OA_type: closed access
_id: '22435'
abstract:
- lang: eng
text: Regions of vegetation transitions (ecotones) are known to be highly sensitive
to climate fluctuations. In this study, the Cellular-Automata Tree Grass Shrub
Simulator (CATGraSS) has been modified, calibrated and used with downscaled future
climate scenarios to examine the role of climate change on vegetation patterns
in a steep mountainous catchment (1.3 km2) located in Sicily, Italy. In the catchment,
north-facing slopes are mostly covered by trees and grass, and south-facing slopes
by Indian Fig opuntia and grass, with grasses dominating as elevation grows. CATGraSS
simulates solar radiation, evapotranspiration, and soil moisture in space and
time. Each model cell can hold a single plant type or can be bare soil. Plant
competition is modeled explicitly through mortality and the establishment of individual
plants in open spaces. In this study, CATGraSS is modified to account for heterogeneity
in soil thickness and tested in the study catchment using the historical climate
of the region. Predicted vegetation patterns are compared with those obtained
from satellite images. Results of model under current climate underscore the importance
of solar irradiance and soil thickness, especially in the uplands where soil is
shallow, in determining vegetation composition over complex terrain. A stochastic
weather generator is used to generate future climate change scenarios for the
catchment by downscaling GCM realizations in space and time. Future increase in
atmospheric CO2 concentration was considered through modifying the vegetation
water use efficiency and stomatal resistance for our study site. Model results
suggest that vegetation pattern is highly sensitive to temperature and rainfall
variations provided by climate scenarios (30% reduction of the annual precipitation
and a 2.8 °C increase of the mean annual temperature). Future climate change is
predicted to bring a considerable reorganization of the plant composition following
topographic patterns, leading to a decrease of trees cover at the expenses of
a grass expansion, which will cause loss of landscape vegetation diversity.
article_processing_charge: No
article_type: original
author:
- first_name: Domenico
full_name: Caracciolo, Domenico
last_name: Caracciolo
- first_name: Leonardo Valerio
full_name: Noto, Leonardo Valerio
last_name: Noto
- first_name: Erkan
full_name: Istanbulluoglu, Erkan
last_name: Istanbulluoglu
- first_name: Simone
full_name: Fatichi, Simone
id: cf8e546b-a9b0-11f0-a43b-aa89ed1b56d6
last_name: Fatichi
- first_name: Xiaochi
full_name: Zhou, Xiaochi
last_name: Zhou
citation:
ama: 'Caracciolo D, Noto LV, Istanbulluoglu E, Fatichi S, Zhou X. Climate change
and Ecotone boundaries: Insights from a cellular automata ecohydrology model in
a Mediterranean catchment with topography controlled vegetation patterns. Advances
in Water Resources. 2014;73:159-175. doi:10.1016/j.advwatres.2014.08.001'
apa: 'Caracciolo, D., Noto, L. V., Istanbulluoglu, E., Fatichi, S., & Zhou,
X. (2014). Climate change and Ecotone boundaries: Insights from a cellular automata
ecohydrology model in a Mediterranean catchment with topography controlled vegetation
patterns. Advances in Water Resources. Elsevier. https://doi.org/10.1016/j.advwatres.2014.08.001'
chicago: 'Caracciolo, Domenico, Leonardo Valerio Noto, Erkan Istanbulluoglu, Simone
Fatichi, and Xiaochi Zhou. “Climate Change and Ecotone Boundaries: Insights from
a Cellular Automata Ecohydrology Model in a Mediterranean Catchment with Topography
Controlled Vegetation Patterns.” Advances in Water Resources. Elsevier,
2014. https://doi.org/10.1016/j.advwatres.2014.08.001.'
ieee: 'D. Caracciolo, L. V. Noto, E. Istanbulluoglu, S. Fatichi, and X. Zhou, “Climate
change and Ecotone boundaries: Insights from a cellular automata ecohydrology
model in a Mediterranean catchment with topography controlled vegetation patterns,”
Advances in Water Resources, vol. 73. Elsevier, pp. 159–175, 2014.'
ista: 'Caracciolo D, Noto LV, Istanbulluoglu E, Fatichi S, Zhou X. 2014. Climate
change and Ecotone boundaries: Insights from a cellular automata ecohydrology
model in a Mediterranean catchment with topography controlled vegetation patterns.
Advances in Water Resources. 73, 159–175.'
mla: 'Caracciolo, Domenico, et al. “Climate Change and Ecotone Boundaries: Insights
from a Cellular Automata Ecohydrology Model in a Mediterranean Catchment with
Topography Controlled Vegetation Patterns.” Advances in Water Resources,
vol. 73, Elsevier, 2014, pp. 159–75, doi:10.1016/j.advwatres.2014.08.001.'
short: D. Caracciolo, L.V. Noto, E. Istanbulluoglu, S. Fatichi, X. Zhou, Advances
in Water Resources 73 (2014) 159–175.
das_tickbox: '1'
date_created: 2026-07-27T12:30:23Z
date_published: 2014-11-01T00:00:00Z
date_updated: 2026-08-12T14:11:56Z
day: '01'
doi: 10.1016/j.advwatres.2014.08.001
extern: '1'
fulldoi: https://doi.org/10.1016/j.advwatres.2014.08.001
intvolume: ' 73'
keyword:
- CA model
- Climate change
- Ecohydrology
- Topography
language:
- iso: eng
month: '11'
oa_version: None
page: 159-175
publication: Advances in Water Resources
publication_identifier:
issn:
- 0309-1708
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Climate change and Ecotone boundaries: Insights from a cellular automata ecohydrology
model in a Mediterranean catchment with topography controlled vegetation patterns'
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 73
year: '2014'
...
---
OA_type: closed access
_id: '22459'
abstract:
- lang: eng
text: Projections of climate change effects in streamflow are increasingly required
to plan water management strategies. These projections are however largely uncertain
due to the spread among climate model realizations, internal climate variability,
and difficulties in transferring climate model results at the spatial and temporal
scales required by catchment hydrology. A combination of a stochastic downscaling
methodology and distributed hydrological modeling was used in the ACQWA project
to provide projections of future streamflow (up to year 2050) for the upper Po
and Rhone basins, respectively located in northern Italy and south-western Switzerland.
Results suggest that internal (stochastic) climate variability is a fundamental
source of uncertainty, typically comparable or larger than the projected climate
change signal. Therefore, climate change effects in streamflow mean, frequency,
and seasonality can be masked by natural climatic fluctuations in large parts
of the analyzed regions. An exception to the overwhelming role of stochastic variability
is represented by high elevation catchments fed by glaciers where streamflow is
expected to be considerably reduced due to glacier retreat, with consequences
appreciable in the main downstream rivers in August and September. Simulations
also identify regions (west upper Rhone and Toce, Ticino river basins) where a
strong precipitation increase in the February to April period projects streamflow
beyond the range of natural climate variability during the melting season. This
study emphasizes the importance of including internal climate variability in climate
change analyses, especially when compared to the limited uncertainty that would
be accounted for by few deterministic projections. The presented results could
be useful in guiding more specific impact studies, although design or management
decisions should be better based on reliability and vulnerability criteria as
suggested by recent literature.
article_processing_charge: No
article_type: original
author:
- first_name: Simone
full_name: Fatichi, Simone
id: cf8e546b-a9b0-11f0-a43b-aa89ed1b56d6
last_name: Fatichi
- first_name: S.
full_name: Rimkus, S.
last_name: Rimkus
- first_name: P.
full_name: Burlando, P.
last_name: Burlando
- first_name: R.
full_name: Bordoy, R.
last_name: Bordoy
citation:
ama: Fatichi S, Rimkus S, Burlando P, Bordoy R. Does internal climate variability
overwhelm climate change signals in streamflow? The upper Po and Rhone basin case
studies. Science of The Total Environment. 2014;493:1171-1182. doi:10.1016/j.scitotenv.2013.12.014
apa: Fatichi, S., Rimkus, S., Burlando, P., & Bordoy, R. (2014). Does internal
climate variability overwhelm climate change signals in streamflow? The upper
Po and Rhone basin case studies. Science of The Total Environment. Elsevier.
https://doi.org/10.1016/j.scitotenv.2013.12.014
chicago: Fatichi, Simone, S. Rimkus, P. Burlando, and R. Bordoy. “Does Internal
Climate Variability Overwhelm Climate Change Signals in Streamflow? The Upper
Po and Rhone Basin Case Studies.” Science of The Total Environment. Elsevier,
2014. https://doi.org/10.1016/j.scitotenv.2013.12.014.
ieee: S. Fatichi, S. Rimkus, P. Burlando, and R. Bordoy, “Does internal climate
variability overwhelm climate change signals in streamflow? The upper Po and Rhone
basin case studies,” Science of The Total Environment, vol. 493. Elsevier,
pp. 1171–1182, 2014.
ista: Fatichi S, Rimkus S, Burlando P, Bordoy R. 2014. Does internal climate variability
overwhelm climate change signals in streamflow? The upper Po and Rhone basin case
studies. Science of The Total Environment. 493, 1171–1182.
mla: Fatichi, Simone, et al. “Does Internal Climate Variability Overwhelm Climate
Change Signals in Streamflow? The Upper Po and Rhone Basin Case Studies.” Science
of The Total Environment, vol. 493, Elsevier, 2014, pp. 1171–82, doi:10.1016/j.scitotenv.2013.12.014.
short: S. Fatichi, S. Rimkus, P. Burlando, R. Bordoy, Science of The Total Environment
493 (2014) 1171–1182.
das_tickbox: '1'
date_created: 2026-07-27T12:30:23Z
date_published: 2014-09-15T00:00:00Z
date_updated: 2026-08-12T14:17:26Z
day: '15'
doi: 10.1016/j.scitotenv.2013.12.014
extern: '1'
external_id:
pmid:
- '24418218'
fulldoi: https://doi.org/10.1016/j.scitotenv.2013.12.014
intvolume: ' 493'
keyword:
- Climate change
- Hydrological modeling
- Stochastic downscaling
- Uncertainty
- Water resources
- Alps
language:
- iso: eng
month: '09'
oa_version: None
page: 1171-1182
pmid: 1
publication: Science of The Total Environment
publication_identifier:
eissn:
- 1879-1026
issn:
- 0048-9697
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Does internal climate variability overwhelm climate change signals in streamflow?
The upper Po and Rhone basin case studies
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 493
year: '2014'
...
---
OA_place: publisher
OA_type: free access
_id: '22460'
abstract:
- lang: eng
text: The biological responses to precipitation within the terrestrial components
of Earth system models, or land surface models (LSMs), are mechanistically simple
and poorly constrained, leaving projections of terrestrial ecosystem functioning
and feedbacks to climate change uncertain. A number of field experiments have
been conducted or are underway to test how changing precipitation will affect
terrestrial ecosystems. Results from these experiments have the potential to vastly
improve modeled processes. However, the transformation of experimental results
into model improvements still represents a grand challenge. Here we review the
current state of precipitation manipulation experiments and the precipitation
responses of biological processes in LSMs to explore how these experiments can
help improve model realism. First, we discuss contemporary precipitation projections
and then review the structure and function of current-generation LSMs. We then
examine different experimental designs and discuss basic variables that, if measured,
would increase a field experiment's usefulness in a modeling context. Next, we
compare biological processes commonly measured in the field with their model analogs
and find that, in many cases, the way these processes are measured in the field
is not compatible with the way they are represented in LSMs, an effect that hinders
model development. We then discuss the challenge of scaling from the plot to the
globe. Finally, we provide a series of recommendations aimed to improve the connectivity
between experiments and LSMs and conclude that studies designed from the perspective
of researchers in both communities will provide the greatest benefit to the broader
global change community.
article_processing_charge: No
article_type: original
author:
- first_name: Nicholas G.
full_name: Smith, Nicholas G.
last_name: Smith
- first_name: Vikki L.
full_name: Rodgers, Vikki L.
last_name: Rodgers
- first_name: Edward R.
full_name: Brzostek, Edward R.
last_name: Brzostek
- first_name: Andrew
full_name: Kulmatiski, Andrew
last_name: Kulmatiski
- first_name: Meghan L.
full_name: Avolio, Meghan L.
last_name: Avolio
- first_name: David L.
full_name: Hoover, David L.
last_name: Hoover
- first_name: Sally E.
full_name: Koerner, Sally E.
last_name: Koerner
- first_name: Kerstin
full_name: Grant, Kerstin
last_name: Grant
- first_name: Anke
full_name: Jentsch, Anke
last_name: Jentsch
- first_name: Simone
full_name: Fatichi, Simone
id: cf8e546b-a9b0-11f0-a43b-aa89ed1b56d6
last_name: Fatichi
- first_name: Dev
full_name: Niyogi, Dev
last_name: Niyogi
citation:
ama: Smith NG, Rodgers VL, Brzostek ER, et al. Toward a better integration of biological
data from precipitation manipulation experiments into Earth system models. Reviews
of Geophysics. 2014;52(3):412-434. doi:10.1002/2014rg000458
apa: Smith, N. G., Rodgers, V. L., Brzostek, E. R., Kulmatiski, A., Avolio, M. L.,
Hoover, D. L., … Niyogi, D. (2014). Toward a better integration of biological
data from precipitation manipulation experiments into Earth system models. Reviews
of Geophysics. American Geophysical Union. https://doi.org/10.1002/2014rg000458
chicago: Smith, Nicholas G., Vikki L. Rodgers, Edward R. Brzostek, Andrew Kulmatiski,
Meghan L. Avolio, David L. Hoover, Sally E. Koerner, et al. “Toward a Better Integration
of Biological Data from Precipitation Manipulation Experiments into Earth System
Models.” Reviews of Geophysics. American Geophysical Union, 2014. https://doi.org/10.1002/2014rg000458.
ieee: N. G. Smith et al., “Toward a better integration of biological data
from precipitation manipulation experiments into Earth system models,” Reviews
of Geophysics, vol. 52, no. 3. American Geophysical Union, pp. 412–434, 2014.
ista: Smith NG, Rodgers VL, Brzostek ER, Kulmatiski A, Avolio ML, Hoover DL, Koerner
SE, Grant K, Jentsch A, Fatichi S, Niyogi D. 2014. Toward a better integration
of biological data from precipitation manipulation experiments into Earth system
models. Reviews of Geophysics. 52(3), 412–434.
mla: Smith, Nicholas G., et al. “Toward a Better Integration of Biological Data
from Precipitation Manipulation Experiments into Earth System Models.” Reviews
of Geophysics, vol. 52, no. 3, American Geophysical Union, 2014, pp. 412–34,
doi:10.1002/2014rg000458.
short: N.G. Smith, V.L. Rodgers, E.R. Brzostek, A. Kulmatiski, M.L. Avolio, D.L.
Hoover, S.E. Koerner, K. Grant, A. Jentsch, S. Fatichi, D. Niyogi, Reviews of
Geophysics 52 (2014) 412–434.
das_tickbox: '1'
date_created: 2026-07-27T12:30:23Z
date_published: 2014-09-01T00:00:00Z
date_updated: 2026-08-12T14:21:11Z
day: '01'
doi: 10.1002/2014rg000458
extern: '1'
fulldoi: https://doi.org/10.1002/2014rg000458
intvolume: ' 52'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1002/2014RG000458
month: '09'
oa: 1
oa_version: Published Version
page: 412-434
publication: Reviews of Geophysics
publication_identifier:
eissn:
- 1944-9208
issn:
- 8755-1209
publication_status: published
publisher: American Geophysical Union
quality_controlled: '1'
scopus_import: '1'
status: public
title: Toward a better integration of biological data from precipitation manipulation
experiments into Earth system models
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 52
year: '2014'
...
---
_id: '1896'
abstract:
- lang: eng
text: 'Biopolymer length regulation is a complex process that involves a large number
of biological, chemical, and physical subprocesses acting simultaneously across
multiple spatial and temporal scales. An illustrative example important for genomic
stability is the length regulation of telomeres - nucleoprotein structures at
the ends of linear chromosomes consisting of tandemly repeated DNA sequences and
a specialized set of proteins. Maintenance of telomeres is often facilitated by
the enzyme telomerase but, particularly in telomerase-free systems, the maintenance
of chromosomal termini depends on alternative lengthening of telomeres (ALT) mechanisms
mediated by recombination. Various linear and circular DNA structures were identified
to participate in ALT, however, dynamics of the whole process is still poorly
understood. We propose a chemical kinetics model of ALT with kinetic rates systematically
derived from the biophysics of DNA diffusion and looping. The reaction system
is reduced to a coagulation-fragmentation system by quasi-steady-state approximation.
The detailed treatment of kinetic rates yields explicit formulas for expected
size distributions of telomeres that demonstrate the key role played by the J
factor, a quantitative measure of bending of polymers. The results are in agreement
with experimental data and point out interesting phenomena: an appearance of very
long telomeric circles if the total telomere density exceeds a critical value
(excess mass) and a nonlinear response of the telomere size distributions to the
amount of telomeric DNA in the system. The results can be of general importance
for understanding dynamics of telomeres in telomerase-independent systems as this
mode of telomere maintenance is similar to the situation in tumor cells lacking
telomerase activity. Furthermore, due to its universality, the model may also
serve as a prototype of an interaction between linear and circular DNA structures
in various settings.'
acknowledgement: The work was supported by the VEGA Grant No. 1/0459/13 (R.K. and
K.B.).
article_number: '032701'
article_processing_charge: No
arxiv: 1
author:
- first_name: Richard
full_name: Kollár, Richard
last_name: Kollár
- first_name: Katarína
full_name: Bod'ová, Katarína
id: 2BA24EA0-F248-11E8-B48F-1D18A9856A87
last_name: Bod'ová
orcid: 0000-0002-7214-0171
- first_name: Jozef
full_name: Nosek, Jozef
last_name: Nosek
- first_name: Ľubomír
full_name: Tomáška, Ľubomír
last_name: Tomáška
citation:
ama: Kollár R, Bodova K, Nosek J, Tomáška Ľ. Mathematical model of alternative mechanism
of telomere length maintenance. Physical Review E. 2014;89(3). doi:10.1103/PhysRevE.89.032701
apa: Kollár, R., Bodova, K., Nosek, J., & Tomáška, Ľ. (2014). Mathematical model
of alternative mechanism of telomere length maintenance. Physical Review E.
American Physical Society. https://doi.org/10.1103/PhysRevE.89.032701
chicago: Kollár, Richard, Katarina Bodova, Jozef Nosek, and Ľubomír Tomáška. “Mathematical
Model of Alternative Mechanism of Telomere Length Maintenance.” Physical Review
E. American Physical Society, 2014. https://doi.org/10.1103/PhysRevE.89.032701.
ieee: R. Kollár, K. Bodova, J. Nosek, and Ľ. Tomáška, “Mathematical model of alternative
mechanism of telomere length maintenance,” Physical Review E, vol. 89,
no. 3. American Physical Society, 2014.
ista: Kollár R, Bodova K, Nosek J, Tomáška Ľ. 2014. Mathematical model of alternative
mechanism of telomere length maintenance. Physical Review E. 89(3), 032701.
mla: Kollár, Richard, et al. “Mathematical Model of Alternative Mechanism of Telomere
Length Maintenance.” Physical Review E, vol. 89, no. 3, 032701, American
Physical Society, 2014, doi:10.1103/PhysRevE.89.032701.
short: R. Kollár, K. Bodova, J. Nosek, Ľ. Tomáška, Physical Review E 89 (2014).
date_created: 2018-12-11T11:54:35Z
date_published: 2014-03-04T00:00:00Z
date_updated: 2026-08-12T14:27:46Z
day: '04'
department:
- _id: NiBa
- _id: GaTk
doi: 10.1103/PhysRevE.89.032701
external_id:
arxiv:
- '1402.0430'
isi:
- '000332274100002'
fulldoi: https://doi.org/10.1103/PhysRevE.89.032701
intvolume: ' 89'
isi: 1
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1402.0430
month: '03'
oa: 1
oa_version: Submitted Version
publication: Physical Review E
publication_status: published
publisher: American Physical Society
publist_id: '5198'
scopus_import: '1'
status: public
title: Mathematical model of alternative mechanism of telomere length maintenance
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 89
year: '2014'
...
---
_id: '2226'
abstract:
- lang: eng
text: Coriolis force effects on shear flows are important in geophysical and astrophysical
contexts. We report a study on the linear stability and the transient energy growth
of the plane Couette flow with system rotation perpendicular to the shear direction.
External rotation causes linear instability. At small rotation rates, the onset
of linear instability scales inversely with the rotation rate and the optimal
transient growth in the linearly stable region is slightly enhanced ∼Re2. The
corresponding optimal initial perturbations are characterized by roll structures
inclined in the streamwise direction and are twisted under external rotation.
At large rotation rates, the transient growth is significantly inhibited and hence
linear stability analysis is a reliable indicator for instability.
article_number: '013001'
article_processing_charge: No
arxiv: 1
author:
- first_name: Liang
full_name: Shi, Liang
last_name: Shi
- first_name: Björn
full_name: Hof, Björn
id: 3A374330-F248-11E8-B48F-1D18A9856A87
last_name: Hof
orcid: 0000-0003-2057-2754
- first_name: Andreas
full_name: Tilgner, Andreas
last_name: Tilgner
citation:
ama: Shi L, Hof B, Tilgner A. Transient growth of Ekman-Couette flow. Physical
Review E. 2014;89(1). doi:10.1103/PhysRevE.89.013001
apa: Shi, L., Hof, B., & Tilgner, A. (2014). Transient growth of Ekman-Couette
flow. Physical Review E. American Physical Society. https://doi.org/10.1103/PhysRevE.89.013001
chicago: Shi, Liang, Björn Hof, and Andreas Tilgner. “Transient Growth of Ekman-Couette
Flow.” Physical Review E. American Physical Society, 2014. https://doi.org/10.1103/PhysRevE.89.013001.
ieee: L. Shi, B. Hof, and A. Tilgner, “Transient growth of Ekman-Couette flow,”
Physical Review E, vol. 89, no. 1. American Physical Society, 2014.
ista: Shi L, Hof B, Tilgner A. 2014. Transient growth of Ekman-Couette flow. Physical
Review E. 89(1), 013001.
mla: Shi, Liang, et al. “Transient Growth of Ekman-Couette Flow.” Physical Review
E, vol. 89, no. 1, 013001, American Physical Society, 2014, doi:10.1103/PhysRevE.89.013001.
short: L. Shi, B. Hof, A. Tilgner, Physical Review E 89 (2014).
corr_author: '1'
date_created: 2018-12-11T11:56:26Z
date_published: 2014-01-06T00:00:00Z
date_updated: 2026-08-12T14:26:10Z
day: '06'
department:
- _id: BjHo
doi: 10.1103/PhysRevE.89.013001
external_id:
arxiv:
- '1312.5095'
isi:
- '000332155800013'
fulldoi: https://doi.org/10.1103/PhysRevE.89.013001
intvolume: ' 89'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1312.5095
month: '01'
oa: 1
oa_version: Submitted Version
project:
- _id: 25BDE9A4-B435-11E9-9278-68D0E5697425
grant_number: SFB-TR3-TP10B
name: "Glutamaterge synaptische Ã\x9Cbertragung und Plastizität in hippocampalen
Mikroschaltkreisen"
publication: Physical Review E
publication_identifier:
issn:
- 1539-3755
publication_status: published
publisher: American Physical Society
publist_id: '4737'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Transient growth of Ekman-Couette flow
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 89
year: '2014'
...
---
_id: '2183'
abstract:
- lang: eng
text: 'We describe a simple adaptive network of coupled chaotic maps. The network
reaches a stationary state (frozen topology) for all values of the coupling parameter,
although the dynamics of the maps at the nodes of the network can be nontrivial.
The structure of the network shows interesting hierarchical properties and in
certain parameter regions the dynamics is polysynchronous: Nodes can be divided
in differently synchronized classes but, contrary to cluster synchronization,
nodes in the same class need not be connected to each other. These complicated
synchrony patterns have been conjectured to play roles in systems biology and
circuits. The adaptive system we study describes ways whereby this behavior can
evolve from undifferentiated nodes.'
acknowledgement: "V.B.S. is partially supported by contract MEC (Grant No. AYA2010-22111-C03-02).\r\n"
article_number: '062809'
article_processing_charge: No
arxiv: 1
author:
- first_name: Vicente
full_name: Botella Soler, Vicente
id: 421234E8-F248-11E8-B48F-1D18A9856A87
last_name: Botella Soler
orcid: 0000-0002-8790-1914
- first_name: Paul
full_name: Glendinning, Paul
last_name: Glendinning
citation:
ama: Botella Soler V, Glendinning P. Hierarchy and polysynchrony in an adaptive
network . Physical Review E. 2014;89(6). doi:10.1103/PhysRevE.89.062809
apa: Botella Soler, V., & Glendinning, P. (2014). Hierarchy and polysynchrony
in an adaptive network . Physical Review E. American Physical Society.
https://doi.org/10.1103/PhysRevE.89.062809
chicago: Botella Soler, Vicente, and Paul Glendinning. “Hierarchy and Polysynchrony
in an Adaptive Network .” Physical Review E. American Physical Society,
2014. https://doi.org/10.1103/PhysRevE.89.062809.
ieee: V. Botella Soler and P. Glendinning, “Hierarchy and polysynchrony in an adaptive
network ,” Physical Review E, vol. 89, no. 6. American Physical Society,
2014.
ista: Botella Soler V, Glendinning P. 2014. Hierarchy and polysynchrony in an adaptive
network . Physical Review E. 89(6), 062809.
mla: Botella Soler, Vicente, and Paul Glendinning. “Hierarchy and Polysynchrony
in an Adaptive Network .” Physical Review E, vol. 89, no. 6, 062809, American
Physical Society, 2014, doi:10.1103/PhysRevE.89.062809.
short: V. Botella Soler, P. Glendinning, Physical Review E 89 (2014).
corr_author: '1'
date_created: 2018-12-11T11:56:11Z
date_published: 2014-06-16T00:00:00Z
date_updated: 2026-08-12T14:27:10Z
day: '16'
department:
- _id: GaTk
doi: 10.1103/PhysRevE.89.062809
ec_funded: 1
external_id:
arxiv:
- '1403.3209'
isi:
- '000337733900007'
fulldoi: https://doi.org/10.1103/PhysRevE.89.062809
intvolume: ' 89'
isi: 1
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1403.3209
month: '06'
oa: 1
oa_version: Preprint
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Physical Review E
publication_status: published
publisher: American Physical Society
publist_id: '4798'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Hierarchy and polysynchrony in an adaptive network '
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 89
year: '2014'
...
---
OA_type: free access
_id: '1980'
abstract:
- lang: eng
text: Non-proton pumping type II NADH dehydrogenase (NDH-2) plays a central role
in the respiratory metabolism of bacteria, and in the mitochondria of fungi, plants
and protists. The lack of NDH-2 in mammalian mitochondria and its essentiality
in important bacterial pathogens suggests these enzymes may represent a potential
new drug target to combat microbial pathogens. Here, we report the first crystal
structure of a bacterial NDH-2 enzyme at 2.5Å resolution from Caldalkalibacillus
thermarum. The NDH-2 structure reveals a homodimeric organization that has a unique
dimer interface. NDH-2 is localized to the cytoplasmic membrane by two separated
C-terminal membrane-anchoring regions that are essential for membrane localization
and FAD binding, but not NDH-2 dimerization. Comparison of bacterial NDH-2 with
the yeast NADH dehydrogenase (Ndi1) structure revealed non-overlapping binding
sites for quinone and NADH in the bacterial enzyme. The bacterial NDH-2 structure
establishes a framework for the structure-based design of small-molecule inhibitors.
acknowledgement: Funded by Health Research Council of New Zealand Royal Society
of New Zealand University of Otago New Zealand Synchrotron Group
article_processing_charge: No
article_type: original
author:
- first_name: Adam
full_name: Heikal, Adam
last_name: Heikal
- first_name: Yoshio
full_name: Nakatani, Yoshio
last_name: Nakatani
- first_name: Elyse
full_name: Dunn, Elyse
last_name: Dunn
- first_name: Marion
full_name: Weimar, Marion
last_name: Weimar
- first_name: Catherine
full_name: Day, Catherine
last_name: Day
- first_name: Edward
full_name: Baker, Edward
last_name: Baker
- first_name: Shaun
full_name: Lott, Shaun
last_name: Lott
- first_name: Leonid A
full_name: Sazanov, Leonid A
id: 338D39FE-F248-11E8-B48F-1D18A9856A87
last_name: Sazanov
orcid: 0000-0002-0977-7989
- first_name: Gregory
full_name: Cook, Gregory
last_name: Cook
citation:
ama: 'Heikal A, Nakatani Y, Dunn E, et al. Structure of the bacterial type II NADH
dehydrogenase: a monotopic membrane protein with an essential role in energy generation.
Molecular Microbiology. 2014;91(5):950-964. doi:10.1111/mmi.12507'
apa: 'Heikal, A., Nakatani, Y., Dunn, E., Weimar, M., Day, C., Baker, E., … Cook,
G. (2014). Structure of the bacterial type II NADH dehydrogenase: a monotopic
membrane protein with an essential role in energy generation. Molecular Microbiology.
Wiley-Blackwell. https://doi.org/10.1111/mmi.12507'
chicago: 'Heikal, Adam, Yoshio Nakatani, Elyse Dunn, Marion Weimar, Catherine Day,
Edward Baker, Shaun Lott, Leonid A Sazanov, and Gregory Cook. “Structure of the
Bacterial Type II NADH Dehydrogenase: A Monotopic Membrane Protein with an Essential
Role in Energy Generation.” Molecular Microbiology. Wiley-Blackwell, 2014.
https://doi.org/10.1111/mmi.12507.'
ieee: 'A. Heikal et al., “Structure of the bacterial type II NADH dehydrogenase:
a monotopic membrane protein with an essential role in energy generation,” Molecular
Microbiology, vol. 91, no. 5. Wiley-Blackwell, pp. 950–964, 2014.'
ista: 'Heikal A, Nakatani Y, Dunn E, Weimar M, Day C, Baker E, Lott S, Sazanov LA,
Cook G. 2014. Structure of the bacterial type II NADH dehydrogenase: a monotopic
membrane protein with an essential role in energy generation. Molecular Microbiology.
91(5), 950–964.'
mla: 'Heikal, Adam, et al. “Structure of the Bacterial Type II NADH Dehydrogenase:
A Monotopic Membrane Protein with an Essential Role in Energy Generation.” Molecular
Microbiology, vol. 91, no. 5, Wiley-Blackwell, 2014, pp. 950–64, doi:10.1111/mmi.12507.'
short: A. Heikal, Y. Nakatani, E. Dunn, M. Weimar, C. Day, E. Baker, S. Lott, L.A.
Sazanov, G. Cook, Molecular Microbiology 91 (2014) 950–964.
date_created: 2018-12-11T11:55:01Z
date_published: 2014-03-01T00:00:00Z
date_updated: 2026-09-04T11:27:46Z
day: '01'
doi: 10.1111/mmi.12507
extern: '1'
external_id:
pmid:
- '24444429'
fulldoi: https://doi.org/10.1111/mmi.12507
intvolume: ' 91'
issue: '5'
language:
- iso: eng
month: '03'
oa_version: None
page: 950 - 964
pmid: 1
publication: Molecular Microbiology
publication_identifier:
eissn:
- 1365-2958
issn:
- 0950-382X
publication_status: published
publisher: Wiley-Blackwell
publist_id: '5103'
status: public
title: 'Structure of the bacterial type II NADH dehydrogenase: a monotopic membrane
protein with an essential role in energy generation'
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 91
year: '2014'
...
---
OA_type: closed access
_id: '1791'
abstract:
- lang: eng
text: Acute gene inactivation using short hairpin RNA (shRNA, knockdown) in developing
brain is a powerful technique to study genetic function; however, discrepancies
between knockdown and knockout murine phenotypes have left unanswered questions.
For example, doublecortin (Dcx) knockdown but not knockout shows a neocortical
neuronal migration phenotype. Here we report that in utero electroporation of
shRNA, but not siRNA or miRNA, to Dcx demonstrates a migration phenotype in Dcx
knockouts akin to the effect in wild-type mice, suggestingshRNA-mediated off-target
toxicity. This effect wasnot limited to Dcx, as it was observed in Dclk1 knockouts,
as well as with a fraction of scrambled shRNAs, suggesting a sequence-dependent
but not sequence-specific effect. Profiling RNAs from electroporated cells showed
a defect in endogenous let7 miRNA levels, and disruption of let7 or Dicer recapitulated
the migration defect. The results suggest that shRNA-mediated knockdown can produce
untoward migration effects by altering endogenous miRNA pathways.
acknowledgement: This work was supported by the National Institutes of Health R01NS41537.
G.K. was supported by an EMBO Long Term Fellowship, S.L.B. by the A.P. Giannini
Fellowship, and A.G.F. by the Brain Behavior Research Foundation
article_processing_charge: No
article_type: original
author:
- first_name: Seungtae
full_name: Baek, Seungtae
last_name: Baek
- first_name: Géraldine
full_name: Kerjan, Géraldine
last_name: Kerjan
- first_name: Stephanie
full_name: Bielas, Stephanie
last_name: Bielas
- first_name: Jieun
full_name: Lee, Jieun
last_name: Lee
- first_name: Ali
full_name: Fenstermaker, Ali
last_name: Fenstermaker
- first_name: Gaia
full_name: Novarino, Gaia
id: 3E57A680-F248-11E8-B48F-1D18A9856A87
last_name: Novarino
orcid: 0000-0002-7673-7178
- first_name: Joseph
full_name: Gleeson, Joseph
last_name: Gleeson
citation:
ama: Baek S, Kerjan G, Bielas S, et al. Off-target effect of doublecortin family
shRNA on neuronal migration associated with endogenous MicroRNA dysregulation.
Neuron. 2014;82(6):1255-1262. doi:10.1016/j.neuron.2014.04.036
apa: Baek, S., Kerjan, G., Bielas, S., Lee, J., Fenstermaker, A., Novarino, G.,
& Gleeson, J. (2014). Off-target effect of doublecortin family shRNA on neuronal
migration associated with endogenous MicroRNA dysregulation. Neuron. Elsevier.
https://doi.org/10.1016/j.neuron.2014.04.036
chicago: Baek, Seungtae, Géraldine Kerjan, Stephanie Bielas, Jieun Lee, Ali Fenstermaker,
Gaia Novarino, and Joseph Gleeson. “Off-Target Effect of Doublecortin Family ShRNA
on Neuronal Migration Associated with Endogenous MicroRNA Dysregulation.” Neuron.
Elsevier, 2014. https://doi.org/10.1016/j.neuron.2014.04.036.
ieee: S. Baek et al., “Off-target effect of doublecortin family shRNA on
neuronal migration associated with endogenous MicroRNA dysregulation,” Neuron,
vol. 82, no. 6. Elsevier, pp. 1255–1262, 2014.
ista: Baek S, Kerjan G, Bielas S, Lee J, Fenstermaker A, Novarino G, Gleeson J.
2014. Off-target effect of doublecortin family shRNA on neuronal migration associated
with endogenous MicroRNA dysregulation. Neuron. 82(6), 1255–1262.
mla: Baek, Seungtae, et al. “Off-Target Effect of Doublecortin Family ShRNA on Neuronal
Migration Associated with Endogenous MicroRNA Dysregulation.” Neuron, vol.
82, no. 6, Elsevier, 2014, pp. 1255–62, doi:10.1016/j.neuron.2014.04.036.
short: S. Baek, G. Kerjan, S. Bielas, J. Lee, A. Fenstermaker, G. Novarino, J. Gleeson,
Neuron 82 (2014) 1255–1262.
date_created: 2018-12-11T11:54:01Z
date_published: 2014-06-18T00:00:00Z
date_updated: 2026-09-04T11:50:27Z
day: '18'
doi: 10.1016/j.neuron.2014.04.036
extern: '1'
external_id:
pmid:
- '24945770'
fulldoi: https://doi.org/10.1016/j.neuron.2014.04.036
intvolume: ' 82'
issue: '6'
language:
- iso: eng
month: '06'
oa_version: None
page: 1255 - 1262
pmid: 1
publication: Neuron
publication_identifier:
eissn:
- 1097-4199
issn:
- 0896-6273
publication_status: published
publisher: Elsevier
publist_id: '5322'
status: public
title: Off-target effect of doublecortin family shRNA on neuronal migration associated
with endogenous MicroRNA dysregulation
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 82
year: '2014'
...