---
OA_place: repository
OA_type: green
_id: '18726'
abstract:
- lang: eng
text: The high sensitivity of JWST will open a new window on the end of the cosmological
dark ages. Small stellar clusters, with a stellar mass of several × 106 M⊙, and
low-mass black holes (BHs), with a mass of several $× 105 M⊙ should be directly
detectable out to redshift z = 10, and individual supernovae (SNe) and gamma ray
burst GRB afterglows are bright enough to be visible beyond this redshift. Dense
primordial gas, in the process of collapsing from large scales to form protogalaxies,
may also be possible to image through diffuse recombination line emission, possibly
even before stars or BHs are formed. In this article, I discuss the key physical
processes that are expected to have determined the sizes of the first star–clusters
and black holes, and the prospect of studying these objects by direct detections
with JWST and with other instruments. The direct light emitted by the very first
stellar clusters and intermediate-mass black holes at z > 10 will likely fall
below JWST’s detection threshold. However, JWST could reveal a decline at the
faint-end of the high-redshift luminosity function, and thereby shed light on
radiative and other feedback effects that operate at these early epochs. JWST
will also have the sensitivity to detect individual SNe from beyond z = 10. In
a dedicated survey lasting for several weeks, thousands of SNe could be detected
at z > 6, with a redshift distribution extending to the formation of the very
first stars at z ≳ 15. Using these SNe as tracers may be the only method to map
out the earliest stages of the cosmic star–formation history. Finally, we point
out that studying the earliest objects at high redshift will also offer a new
window on the primordial power spectrum, on ∼100 times smaller scales than probed
by current large-scale structure data.
alternative_title:
- Astrophysics and Space Science Proceedings
article_processing_charge: No
arxiv: 1
author:
- first_name: Zoltán
full_name: Haiman, Zoltán
id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
last_name: Haiman
orcid: 0000-0003-3633-5403
citation:
ama: 'Haiman Z. Observing the first stars and black holes. In: Astrophysics and
Space Science Proceedings. Dordrecht: Springer Nature; 2009:385-418. doi:10.1007/978-1-4020-9457-6_15'
apa: 'Haiman, Z. (2009). Observing the first stars and black holes. In Astrophysics
and Space Science Proceedings (pp. 385–418). Dordrecht: Springer Nature. https://doi.org/10.1007/978-1-4020-9457-6_15'
chicago: 'Haiman, Zoltán. “Observing the First Stars and Black Holes.” In Astrophysics
and Space Science Proceedings, 385–418. Dordrecht: Springer Nature, 2009.
https://doi.org/10.1007/978-1-4020-9457-6_15.'
ieee: Z. Haiman, “Observing the first stars and black holes,” in Astrophysics
and Space Science Proceedings, 2009, pp. 385–418.
ista: Haiman Z. 2009. Observing the first stars and black holes. Astrophysics and
Space Science Proceedings. , Astrophysics and Space Science Proceedings, , 385–418.
mla: Haiman, Zoltán. “Observing the First Stars and Black Holes.” Astrophysics
and Space Science Proceedings, Springer Nature, 2009, pp. 385–418, doi:10.1007/978-1-4020-9457-6_15.
short: Z. Haiman, in:, Astrophysics and Space Science Proceedings, Springer Nature,
Dordrecht, 2009, pp. 385–418.
date_created: 2025-01-03T12:09:18Z
date_published: 2009-01-01T00:00:00Z
date_updated: 2025-01-03T12:14:49Z
day: '01'
doi: 10.1007/978-1-4020-9457-6_15
extern: '1'
external_id:
arxiv:
- '0809.3926'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/0809.3926
month: '01'
oa: 1
oa_version: Preprint
page: 385-418
place: Dordrecht
publication: Astrophysics and Space Science Proceedings
publication_identifier:
eisbn:
- '9781402094576'
eissn:
- 1570-6605
isbn:
- '9781402094569'
issn:
- 1570-6591
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Observing the first stars and black holes
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2009'
...
---
OA_place: repository
OA_type: green
_id: '18735'
abstract:
- lang: eng
text: The high sensitivity of JWST will open a new window on the end of the cosmological
dark ages. Small stellar clusters, with a stellar mass of several × 106 M⊙, and
low-mass black holes (BHs), with a mass of several $× 105 M⊙ should be directly
detectable out to redshift z = 10, and individual supernovae (SNe) and gamma ray
burst GRB afterglows are bright enough to be visible beyond this redshift. Dense
primordial gas, in the process of collapsing from large scales to form protogalaxies,
may also be possible to image through diffuse recombination line emission, possibly
even before stars or BHs are formed. In this article, I discuss the key physical
processes that are expected to have determined the sizes of the first star–clusters
and black holes, and the prospect of studying these objects by direct detections
with JWST and with other instruments. The direct light emitted by the very first
stellar clusters and intermediate-mass black holes at z > 10 will likely fall
below JWST’s detection threshold. However, JWST could reveal a decline at the
faint-end of the high-redshift luminosity function, and thereby shed light on
radiative and other feedback effects that operate at these early epochs. JWST
will also have the sensitivity to detect individual SNe from beyond z = 10. In
a dedicated survey lasting for several weeks, thousands of SNe could be detected
at z > 6, with a redshift distribution extending to the formation of the very
first stars at z ≳ 15. Using these SNe as tracers may be the only method to map
out the earliest stages of the cosmic star–formation history. Finally, we point
out that studying the earliest objects at high redshift will also offer a new
window on the primordial power spectrum, on ∼100 times smaller scales than probed
by current large-scale structure data.
alternative_title:
- Astrophysics and Space Science Proceedings
article_processing_charge: No
arxiv: 1
author:
- first_name: Zoltán
full_name: Haiman, Zoltán
id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
last_name: Haiman
orcid: 0000-0003-3633-5403
citation:
ama: 'Haiman Z. Observing the First Stars and Black Holes. In: Thronson HA, Stiavelli
M, Tielens A, eds. Astrophysics in the Next Decade. Springer Nature; 2009:385-418.
doi:10.1007/978-1-4020-9457-6_15'
apa: Haiman, Z. (2009). Observing the First Stars and Black Holes. In H. A. Thronson,
M. Stiavelli, & A. Tielens (Eds.), Astrophysics in the Next Decade
(pp. 385–418). Springer Nature. https://doi.org/10.1007/978-1-4020-9457-6_15
chicago: Haiman, Zoltán. “Observing the First Stars and Black Holes.” In Astrophysics
in the Next Decade, edited by Harley A. Thronson, Massimo Stiavelli, and Alexander
Tielens, 385–418. Springer Nature, 2009. https://doi.org/10.1007/978-1-4020-9457-6_15.
ieee: Z. Haiman, “Observing the First Stars and Black Holes,” in Astrophysics
in the Next Decade, H. A. Thronson, M. Stiavelli, and A. Tielens, Eds. Springer
Nature, 2009, pp. 385–418.
ista: 'Haiman Z. 2009.Observing the First Stars and Black Holes. In: Astrophysics
in the Next Decade. Astrophysics and Space Science Proceedings, , 385–418.'
mla: Haiman, Zoltán. “Observing the First Stars and Black Holes.” Astrophysics
in the Next Decade, edited by Harley A. Thronson et al., Springer Nature,
2009, pp. 385–418, doi:10.1007/978-1-4020-9457-6_15.
short: Z. Haiman, in:, H.A. Thronson, M. Stiavelli, A. Tielens (Eds.), Astrophysics
in the Next Decade, Springer Nature, 2009, pp. 385–418.
date_created: 2025-01-03T12:29:16Z
date_published: 2009-02-11T00:00:00Z
date_updated: 2025-01-07T12:52:13Z
day: '11'
doi: 10.1007/978-1-4020-9457-6_15
editor:
- first_name: Harley A.
full_name: Thronson, Harley A.
last_name: Thronson
- first_name: Massimo
full_name: Stiavelli, Massimo
last_name: Stiavelli
- first_name: Alexander
full_name: Tielens, Alexander
last_name: Tielens
extern: '1'
external_id:
arxiv:
- '0809.3926'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/0809.3926
month: '02'
oa: 1
oa_version: Preprint
page: 385-418
publication: Astrophysics in the Next Decade
publication_identifier:
eisbn:
- '9781402094576'
eissn:
- 1570-6605
isbn:
- '9781402094569'
issn:
- 1570-6591
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Observing the First Stars and Black Holes
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2009'
...
---
_id: '12654'
abstract:
- lang: eng
text: 'We investigate the transferability of an enhanced temperature-index melt
model that was developed and tested on Haut Glacier d’Arolla, Switzerland, in
the 2001 season. The model’s empirical parameters (temperature factor, TF, and
shortwave radiation factor, SRF) are recalibrated for: (1) other locations on
Haut Glacier d’Arolla; (2) subperiods of distinct meteorological conditions; (3)
different years on Haut Glacier d’Arolla; and (4) other glaciers in different
years. The model parameters are optimized against simulations of an energy-balance
model validated against ablation observations. Results are compared with those
obtained with the original parameters. The model works very well when applied
to other sites, seasons and glaciers, with the exception of overcast conditions.
Differences are due to underestimation of high melt rates. The parameter values
are associated with the prevailing energy-balance conditions, showing that high
SRF are obtained on clear-sky days, whereas higher TF are typical of locations
where glacier winds prevail and turbulent fluxes are high. We also provide a range
of parameters clearly associated with the site’s location and its meteorological
characteristics that could help to assign parameter values to sites where few
data are available.'
article_processing_charge: No
article_type: original
author:
- first_name: Marco
full_name: Carenzo, Marco
last_name: Carenzo
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
orcid: 0000-0002-5554-8087
- first_name: Stefan
full_name: Rimkus, Stefan
last_name: Rimkus
- first_name: Paolo
full_name: Burlando, Paolo
last_name: Burlando
citation:
ama: Carenzo M, Pellicciotti F, Rimkus S, Burlando P. Assessing the transferability
and robustness of an enhanced temperature-index glacier-melt model. Journal
of Glaciology. 2009;55(190):258-274. doi:10.3189/002214309788608804
apa: Carenzo, M., Pellicciotti, F., Rimkus, S., & Burlando, P. (2009). Assessing
the transferability and robustness of an enhanced temperature-index glacier-melt
model. Journal of Glaciology. Cambridge University Press. https://doi.org/10.3189/002214309788608804
chicago: Carenzo, Marco, Francesca Pellicciotti, Stefan Rimkus, and Paolo Burlando.
“Assessing the Transferability and Robustness of an Enhanced Temperature-Index
Glacier-Melt Model.” Journal of Glaciology. Cambridge University Press,
2009. https://doi.org/10.3189/002214309788608804.
ieee: M. Carenzo, F. Pellicciotti, S. Rimkus, and P. Burlando, “Assessing the transferability
and robustness of an enhanced temperature-index glacier-melt model,” Journal
of Glaciology, vol. 55, no. 190. Cambridge University Press, pp. 258–274,
2009.
ista: Carenzo M, Pellicciotti F, Rimkus S, Burlando P. 2009. Assessing the transferability
and robustness of an enhanced temperature-index glacier-melt model. Journal of
Glaciology. 55(190), 258–274.
mla: Carenzo, Marco, et al. “Assessing the Transferability and Robustness of an
Enhanced Temperature-Index Glacier-Melt Model.” Journal of Glaciology,
vol. 55, no. 190, Cambridge University Press, 2009, pp. 258–74, doi:10.3189/002214309788608804.
short: M. Carenzo, F. Pellicciotti, S. Rimkus, P. Burlando, Journal of Glaciology
55 (2009) 258–274.
date_created: 2023-02-20T08:18:34Z
date_published: 2009-03-01T00:00:00Z
date_updated: 2024-10-14T12:00:39Z
day: '01'
doi: 10.3189/002214309788608804
extern: '1'
intvolume: ' 55'
issue: '190'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.3189/002214309788608804
month: '03'
oa: 1
oa_version: Published Version
page: 258-274
publication: Journal of Glaciology
publication_identifier:
eissn:
- 1727-5652
issn:
- 0022-1430
publication_status: published
publisher: Cambridge University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Assessing the transferability and robustness of an enhanced temperature-index
glacier-melt model
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 55
year: '2009'
...
---
_id: '12655'
abstract:
- lang: eng
text: We discuss the inclusion of the subsurface heat-conduction flux into the calculation
of the energy balance and ablation at the glacier–atmosphere interface. Data from
automatic weather stations are used to force an energy-balance model at several
locations on alpine glaciers and at one site in the dry Andes of central Chile.
The heat-conduction flux is computed using a two-layer scheme, assuming that 36%
of the net shortwave radiation is absorbed by the surface layer and that the rest
penetrates into the snowpack. We compare simulations conducted with and without
subsurface heat flux. Results show that assuming a surface temperature of zero
degrees leads to a larger overestimation of melt at the sites in the accumulation
area (10.4–13.3%) than in the ablation area (0.5–2.8%), due to lower air temperatures
and the presence of snow. The difference between simulations with and without
heat conduction is also high at the beginning and end of the ablation season (up
to 29% for the first 15 days of the season), when air temperatures are lower and
snow covers the glacier surface, while they are of little importance during periods
of sustained melt at all the locations investigated.
article_processing_charge: No
article_type: original
author:
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
orcid: 0000-0002-5554-8087
- first_name: Marco
full_name: Carenzo, Marco
last_name: Carenzo
- first_name: Jakob
full_name: Helbing, Jakob
last_name: Helbing
- first_name: Stefan
full_name: Rimkus, Stefan
last_name: Rimkus
- first_name: Paolo
full_name: Burlando, Paolo
last_name: Burlando
citation:
ama: Pellicciotti F, Carenzo M, Helbing J, Rimkus S, Burlando P. On the role of
subsurface heat conduction in glacier energy-balance modelling. Annals of Glaciology.
2009;50(50):16-24. doi:10.3189/172756409787769555
apa: Pellicciotti, F., Carenzo, M., Helbing, J., Rimkus, S., & Burlando, P.
(2009). On the role of subsurface heat conduction in glacier energy-balance modelling.
Annals of Glaciology. International Glaciological Society. https://doi.org/10.3189/172756409787769555
chicago: Pellicciotti, Francesca, Marco Carenzo, Jakob Helbing, Stefan Rimkus, and
Paolo Burlando. “On the Role of Subsurface Heat Conduction in Glacier Energy-Balance
Modelling.” Annals of Glaciology. International Glaciological Society,
2009. https://doi.org/10.3189/172756409787769555.
ieee: F. Pellicciotti, M. Carenzo, J. Helbing, S. Rimkus, and P. Burlando, “On the
role of subsurface heat conduction in glacier energy-balance modelling,” Annals
of Glaciology, vol. 50, no. 50. International Glaciological Society, pp. 16–24,
2009.
ista: Pellicciotti F, Carenzo M, Helbing J, Rimkus S, Burlando P. 2009. On the role
of subsurface heat conduction in glacier energy-balance modelling. Annals of Glaciology.
50(50), 16–24.
mla: Pellicciotti, Francesca, et al. “On the Role of Subsurface Heat Conduction
in Glacier Energy-Balance Modelling.” Annals of Glaciology, vol. 50, no.
50, International Glaciological Society, 2009, pp. 16–24, doi:10.3189/172756409787769555.
short: F. Pellicciotti, M. Carenzo, J. Helbing, S. Rimkus, P. Burlando, Annals of
Glaciology 50 (2009) 16–24.
date_created: 2023-02-20T08:18:40Z
date_published: 2009-01-01T00:00:00Z
date_updated: 2024-10-14T12:00:29Z
day: '01'
doi: 10.3189/172756409787769555
extern: '1'
intvolume: ' 50'
issue: '50'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.3189/172756409787769555
month: '01'
oa: 1
oa_version: Published Version
page: 16-24
publication: Annals of Glaciology
publication_identifier:
eissn:
- 1727-5644
issn:
- 0260-3055
publication_status: published
publisher: International Glaciological Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: On the role of subsurface heat conduction in glacier energy-balance modelling
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 50
year: '2009'
...
---
_id: '1302'
abstract:
- lang: eng
text: 'The nervous system of seeing animals derives information about optic flow
in two subsequent steps. First, local motion vectors are calculated from moving
retinal images, and second, the spatial distribution of these vectors is analyzed
on the dendrites of large downstream neurons. In dipteran flies, this second step
relies on a set of motion-sensitive lobula plate tangential cells (LPTCs), which
have been studied in great detail in large fly species. Yet, studies on neurons
that convey information to LPTCs and neuroanatomical investigations that enable
a mechanistic understanding of the underlying dendritic computations in LPTCs
are rare. We investigated the subcellular distribution of nicotinic acetylcholine
receptors (nAChRs) on two sets of LPTCs: vertical system (VS) and horizontal system
(HS) cells in Drosophila melanogaster. In this paper, we describe that both cell
types express Dα7-type nAChR subunits specifically on higher order dendritic branches,
similar to the expression of gamma aminobutyric acid (GABA) receptors. These findings
support a model in which directional selectivity of LPTCs is achieved by the dendritic
integration of excitatory, cholinergic, and inhibitory GABA-ergic input from local
motion detectors with opposite preferred direction. Nonetheless, whole-cell recordings
in mutant flies without Dα7 nAChRs revealed that direction selectivity of VS and
HS cells is largely retained. In addition, mutant LPTCs were responsive to acetylcholine
and remaining nAChR receptors were labeled by α-bungarotoxin. These results in
LPTCs with genetically manipulated excitatory input synapses suggest a robust
cellular implementation of dendritic processing that warrants direction selectivity.
The underlying mechanism that ensures appropriate nAChR-mediated synaptic currents
and the functional implications of separate sets or heteromultimeric nAChRs can
now be addressed in this system.'
author:
- first_name: Shamprasad
full_name: Raghu, Shamprasad V
last_name: Raghu
- first_name: Maximilian A
full_name: Maximilian Jösch
id: 2BD278E6-F248-11E8-B48F-1D18A9856A87
last_name: Jösch
orcid: 0000-0002-3937-1330
- first_name: Stephan
full_name: Sigrist, Stephan J
last_name: Sigrist
- first_name: Alexander
full_name: Borst, Alexander
last_name: Borst
- first_name: Dierk
full_name: Reiff, Dierk F
last_name: Reiff
citation:
ama: 'Raghu S, Jösch MA, Sigrist S, Borst A, Reiff D. Synaptic organization of lobula
plate tangential cells in Drosophila: Dα7 cholinergic receptors. Journal of
Neurogenetics. 2009;23(1-2):200-209. doi:10.1080/01677060802471684'
apa: 'Raghu, S., Jösch, M. A., Sigrist, S., Borst, A., & Reiff, D. (2009). Synaptic
organization of lobula plate tangential cells in Drosophila: Dα7 cholinergic receptors.
Journal of Neurogenetics. Informa Healthcare. https://doi.org/10.1080/01677060802471684'
chicago: 'Raghu, Shamprasad, Maximilian A Jösch, Stephan Sigrist, Alexander Borst,
and Dierk Reiff. “Synaptic Organization of Lobula Plate Tangential Cells in Drosophila:
Dα7 Cholinergic Receptors.” Journal of Neurogenetics. Informa Healthcare,
2009. https://doi.org/10.1080/01677060802471684.'
ieee: 'S. Raghu, M. A. Jösch, S. Sigrist, A. Borst, and D. Reiff, “Synaptic organization
of lobula plate tangential cells in Drosophila: Dα7 cholinergic receptors,” Journal
of Neurogenetics, vol. 23, no. 1–2. Informa Healthcare, pp. 200–209, 2009.'
ista: 'Raghu S, Jösch MA, Sigrist S, Borst A, Reiff D. 2009. Synaptic organization
of lobula plate tangential cells in Drosophila: Dα7 cholinergic receptors. Journal
of Neurogenetics. 23(1–2), 200–209.'
mla: 'Raghu, Shamprasad, et al. “Synaptic Organization of Lobula Plate Tangential
Cells in Drosophila: Dα7 Cholinergic Receptors.” Journal of Neurogenetics,
vol. 23, no. 1–2, Informa Healthcare, 2009, pp. 200–09, doi:10.1080/01677060802471684.'
short: S. Raghu, M.A. Jösch, S. Sigrist, A. Borst, D. Reiff, Journal of Neurogenetics
23 (2009) 200–209.
date_created: 2018-12-11T11:51:15Z
date_published: 2009-03-01T00:00:00Z
date_updated: 2021-01-12T06:49:44Z
day: '01'
doi: 10.1080/01677060802471684
extern: 1
intvolume: ' 23'
issue: 1-2
month: '03'
page: 200 - 209
publication: Journal of Neurogenetics
publication_status: published
publisher: Informa Healthcare
publist_id: '5972'
quality_controlled: 0
status: public
title: 'Synaptic organization of lobula plate tangential cells in Drosophila: Dα7
cholinergic receptors'
type: journal_article
volume: 23
year: '2009'
...
---
_id: '1983'
abstract:
- lang: eng
text: 'During many cellular processes such as cell division, polarization and motility,
the plasma membrane does not only represent a passive physical barrier, but also
provides a highly dynamic platform for the interplay between lipids, membrane
binding proteins and cytoskeletal elements. Even though many regulators of these
interactions are known, their mutual interdependence appears to be highly complex
and difficult to study in a living cell. Over the past few years, in vitro studies
on membrane-cytoskeleton interactions using biomimetic membranes turned out to
be extremely helpful to get better mechanistic insight into the dynamics of these
processes. In this review, we discuss some of the recent developments using in
vitro assays to dissect the role of the players involved: lipids in the membrane,
proteins binding to membranes and proteins binding to membrane proteins. We also
summarize advantages and disadvantages of supported lipid bilayers as model membrane.'
author:
- first_name: Martin
full_name: Martin Loose
id: 462D4284-F248-11E8-B48F-1D18A9856A87
last_name: Loose
orcid: 0000-0001-7309-9724
- first_name: Petra
full_name: 'Schwille, Petra '
last_name: Schwille
citation:
ama: Loose M, Schwille P. Biomimetic membrane systems to study cellular organization.
Journal of Structural Biology. 2009;168(1):143-151. doi:10.1016/j.jsb.2009.03.016
apa: Loose, M., & Schwille, P. (2009). Biomimetic membrane systems to study
cellular organization. Journal of Structural Biology. Academic Press. https://doi.org/10.1016/j.jsb.2009.03.016
chicago: Loose, Martin, and Petra Schwille. “Biomimetic Membrane Systems to Study
Cellular Organization.” Journal of Structural Biology. Academic Press,
2009. https://doi.org/10.1016/j.jsb.2009.03.016.
ieee: M. Loose and P. Schwille, “Biomimetic membrane systems to study cellular organization,”
Journal of Structural Biology, vol. 168, no. 1. Academic Press, pp. 143–151,
2009.
ista: Loose M, Schwille P. 2009. Biomimetic membrane systems to study cellular organization.
Journal of Structural Biology. 168(1), 143–151.
mla: Loose, Martin, and Petra Schwille. “Biomimetic Membrane Systems to Study Cellular
Organization.” Journal of Structural Biology, vol. 168, no. 1, Academic
Press, 2009, pp. 143–51, doi:10.1016/j.jsb.2009.03.016.
short: M. Loose, P. Schwille, Journal of Structural Biology 168 (2009) 143–151.
date_created: 2018-12-11T11:55:03Z
date_published: 2009-10-01T00:00:00Z
date_updated: 2021-01-12T06:54:30Z
day: '01'
doi: 10.1016/j.jsb.2009.03.016
extern: 1
intvolume: ' 168'
issue: '1'
month: '10'
page: 143 - 151
publication: Journal of Structural Biology
publication_status: published
publisher: Academic Press
publist_id: '5099'
quality_controlled: 0
status: public
title: Biomimetic membrane systems to study cellular organization
type: journal_article
volume: 168
year: '2009'
...
---
_id: '1984'
abstract:
- lang: eng
text: In animal and plant cells, mitotic chromatin locally generates microtubules
that self-organize into a mitotic spindle, and its dimensions and bipolar symmetry
are essential for accurate chromosome segregation. By immobilizing microscopic
chromatin-coated beads on slide surfaces using a microprinting technique, we have
examined the effect of chromatin on the dimensions and symmetry of spindles in
Xenopus laevis cytoplasmic extracts. While circular spots with diameters around
14-18 μm trigger bipolar spindle formation, larger spots generate an incorrect
number of poles. We also examined lines of chromatin with various dimensions.
Their length determined the number of poles that formed, with a 6 × 18 μm rectangular
patch generating normal spindle morphology. Around longer lines, multiple poles
formed and the structures were disorganized. While lines thinner than 10 μm generated
symmetric structures, thicker lines induced the formation of asymmetric structures
where all microtubules are on the same side of the line. Our results show that
chromatin defines spindle shape and orientation. For a video summary of this article,
see the PaperFlick file available with the online Supplemental Data.
acknowledgement: This work was supported by EU contract LSHG-CT-2004-503568 ComBio,
the Spanish ministry of education (M.M.C.), and EU-STREP active BioMics (A.D.).
Research in the Nedelec lab is funded by the Center for Modeling and Simulation
in the Biosciences (http://www.bioms.de), the Volkswagenstiftung, and Human Frontier
Science Program grant RGY84.
author:
- first_name: Ana
full_name: Dinarina, Ana
last_name: Dinarina
- first_name: Céline
full_name: Pugieux, Céline
last_name: Pugieux
- first_name: Maria
full_name: Corral, Maria M
last_name: Corral
- first_name: Martin
full_name: Martin Loose
id: 462D4284-F248-11E8-B48F-1D18A9856A87
last_name: Loose
orcid: 0000-0001-7309-9724
- first_name: Joachim
full_name: Spatz, Joachim P
last_name: Spatz
- first_name: Éric
full_name: Karsenti, Éric
last_name: Karsenti
- first_name: François
full_name: Nédélec, François J
last_name: Nédélec
citation:
ama: Dinarina A, Pugieux C, Corral M, et al. Chromatin shapes the mitotic spindle.
Cell. 2009;138(3):502-513. doi:10.1016/j.cell.2009.05.027
apa: Dinarina, A., Pugieux, C., Corral, M., Loose, M., Spatz, J., Karsenti, É.,
& Nédélec, F. (2009). Chromatin shapes the mitotic spindle. Cell. Cell
Press. https://doi.org/10.1016/j.cell.2009.05.027
chicago: Dinarina, Ana, Céline Pugieux, Maria Corral, Martin Loose, Joachim Spatz,
Éric Karsenti, and François Nédélec. “Chromatin Shapes the Mitotic Spindle.” Cell.
Cell Press, 2009. https://doi.org/10.1016/j.cell.2009.05.027.
ieee: A. Dinarina et al., “Chromatin shapes the mitotic spindle,” Cell,
vol. 138, no. 3. Cell Press, pp. 502–513, 2009.
ista: Dinarina A, Pugieux C, Corral M, Loose M, Spatz J, Karsenti É, Nédélec F.
2009. Chromatin shapes the mitotic spindle. Cell. 138(3), 502–513.
mla: Dinarina, Ana, et al. “Chromatin Shapes the Mitotic Spindle.” Cell,
vol. 138, no. 3, Cell Press, 2009, pp. 502–13, doi:10.1016/j.cell.2009.05.027.
short: A. Dinarina, C. Pugieux, M. Corral, M. Loose, J. Spatz, É. Karsenti, F. Nédélec,
Cell 138 (2009) 502–513.
date_created: 2018-12-11T11:55:03Z
date_published: 2009-08-07T00:00:00Z
date_updated: 2021-01-12T06:54:30Z
day: '07'
doi: 10.1016/j.cell.2009.05.027
extern: 1
intvolume: ' 138'
issue: '3'
month: '08'
page: 502 - 513
publication: Cell
publication_status: published
publisher: Cell Press
publist_id: '5100'
quality_controlled: 0
status: public
title: Chromatin shapes the mitotic spindle
type: journal_article
volume: 138
year: '2009'
...
---
_id: '2067'
acknowledgement: This work was funded by a Portuguese Foundation for Science and Technology
scholarship to B.V., and B.C. was supported by the Royal Society
author:
- first_name: Beatriz
full_name: Beatriz Vicoso
id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
last_name: Vicoso
orcid: 0000-0002-4579-8306
- first_name: Brian
full_name: Charlesworth, Brian
last_name: Charlesworth
citation:
ama: Vicoso B, Charlesworth B. Recombination rates may affect the ratio of X to
autosomal noncoding polymorphism in African populations of Drosophila melanogaster.
Genetics. 2009;181(4):1699-1701. doi:10.1534/genetics.108.098004
apa: Vicoso, B., & Charlesworth, B. (2009). Recombination rates may affect the
ratio of X to autosomal noncoding polymorphism in African populations of Drosophila
melanogaster. Genetics. Genetics Society of America. https://doi.org/10.1534/genetics.108.098004
chicago: Vicoso, Beatriz, and Brian Charlesworth. “Recombination Rates May Affect
the Ratio of X to Autosomal Noncoding Polymorphism in African Populations of Drosophila
Melanogaster.” Genetics. Genetics Society of America, 2009. https://doi.org/10.1534/genetics.108.098004.
ieee: B. Vicoso and B. Charlesworth, “Recombination rates may affect the ratio of
X to autosomal noncoding polymorphism in African populations of Drosophila melanogaster,”
Genetics, vol. 181, no. 4. Genetics Society of America, pp. 1699–1701,
2009.
ista: Vicoso B, Charlesworth B. 2009. Recombination rates may affect the ratio of
X to autosomal noncoding polymorphism in African populations of Drosophila melanogaster.
Genetics. 181(4), 1699–1701.
mla: Vicoso, Beatriz, and Brian Charlesworth. “Recombination Rates May Affect the
Ratio of X to Autosomal Noncoding Polymorphism in African Populations of Drosophila
Melanogaster.” Genetics, vol. 181, no. 4, Genetics Society of America,
2009, pp. 1699–701, doi:10.1534/genetics.108.098004.
short: B. Vicoso, B. Charlesworth, Genetics 181 (2009) 1699–1701.
date_created: 2018-12-11T11:55:31Z
date_published: 2009-04-01T00:00:00Z
date_updated: 2021-01-12T06:55:06Z
day: '01'
doi: 10.1534/genetics.108.098004
extern: 1
intvolume: ' 181'
issue: '4'
month: '04'
page: 1699 - 1701
publication: Genetics
publication_status: published
publisher: Genetics Society of America
publist_id: '4971'
quality_controlled: 0
status: public
title: Recombination rates may affect the ratio of X to autosomal noncoding polymorphism
in African populations of Drosophila melanogaster
type: journal_article
volume: 181
year: '2009'
...
---
_id: '2068'
abstract:
- lang: eng
text: In Drosophila, there is a consistent deficit of male-biased genes on the X
chromosome. It has been suggested that male-biased genes may evolve from initially
unbiased genes as a result of increased expression levels in males. If transcription
rates are limited, a large increase in expression in the testis may be harder
to achieve for single-copy X-linked genes than for autosomal genes, because they
are already hypertranscribed due to dosage compensation. This hypothesis predicts
that the larger the increase in expression required to make a male-biased gene,
the lower the chance of this being achievable if it is located on the X chromosome.
Consequently, highly expressed male-biased genes should be located on the X chromosome
less often than lowly expressed male-biased genes. This pattern is observed in
our analysis of publicly available data, where microarray data or EST data are
used to detect male-biased genes in D. melanogaster and to measure their expression
levels. This is consistent with the idea that limitations in transcription rates
may prevent male-biased genes from accumulating on the X chromosome.
acknowledgement: This work was funded by a Portuguese Foundation for Science and Technology
scholarship to B.V., and B.C. was supported by the Royal Society
author:
- first_name: Beatriz
full_name: Beatriz Vicoso
id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
last_name: Vicoso
orcid: 0000-0002-4579-8306
- first_name: Brian
full_name: Charlesworth, Brian
last_name: Charlesworth
citation:
ama: 'Vicoso B, Charlesworth B. The deficit of male-biased genes on the D. melanogaster
X chromosome is expression-dependent: A consequence of dosage compensation? Journal
of Molecular Evolution. 2009;68(5):576-583. doi:10.1007/s00239-009-9235-4'
apa: 'Vicoso, B., & Charlesworth, B. (2009). The deficit of male-biased genes
on the D. melanogaster X chromosome is expression-dependent: A consequence of
dosage compensation? Journal of Molecular Evolution. Springer. https://doi.org/10.1007/s00239-009-9235-4'
chicago: 'Vicoso, Beatriz, and Brian Charlesworth. “The Deficit of Male-Biased Genes
on the D. Melanogaster X Chromosome Is Expression-Dependent: A Consequence of
Dosage Compensation?” Journal of Molecular Evolution. Springer, 2009. https://doi.org/10.1007/s00239-009-9235-4.'
ieee: 'B. Vicoso and B. Charlesworth, “The deficit of male-biased genes on the D.
melanogaster X chromosome is expression-dependent: A consequence of dosage compensation?,”
Journal of Molecular Evolution, vol. 68, no. 5. Springer, pp. 576–583,
2009.'
ista: 'Vicoso B, Charlesworth B. 2009. The deficit of male-biased genes on the D.
melanogaster X chromosome is expression-dependent: A consequence of dosage compensation?
Journal of Molecular Evolution. 68(5), 576–583.'
mla: 'Vicoso, Beatriz, and Brian Charlesworth. “The Deficit of Male-Biased Genes
on the D. Melanogaster X Chromosome Is Expression-Dependent: A Consequence of
Dosage Compensation?” Journal of Molecular Evolution, vol. 68, no. 5, Springer,
2009, pp. 576–83, doi:10.1007/s00239-009-9235-4.'
short: B. Vicoso, B. Charlesworth, Journal of Molecular Evolution 68 (2009) 576–583.
date_created: 2018-12-11T11:55:31Z
date_published: 2009-05-01T00:00:00Z
date_updated: 2021-01-12T06:55:06Z
day: '01'
doi: 10.1007/s00239-009-9235-4
extern: 1
intvolume: ' 68'
issue: '5'
month: '05'
page: 576 - 583
publication: Journal of Molecular Evolution
publication_status: published
publisher: Springer
publist_id: '4970'
quality_controlled: 0
status: public
title: 'The deficit of male-biased genes on the D. melanogaster X chromosome is expression-dependent:
A consequence of dosage compensation?'
type: journal_article
volume: 68
year: '2009'
...
---
_id: '2069'
abstract:
- lang: eng
text: Current models of X-linked and autosomal evolutionary rates often assume that
the effective population size of the X chromosome (NeX) is equal to three-quarters
of the autosomal population size (NeA). However, polymorphism studies of Drosophila
melanogaster and D. simulans suggest that there are often significant deviations
from this value. We have computed fixation rates of beneficial and deleterious
mutations at X-linked and autosomal sites when this occurs. We find that NeX/NeA
is a crucial parameter for the rates of evolution of X-linked sites compared to
autosomal sites. Faster-X evolution due to the fixation of beneficial mutations
can occur under a much wider range of levels of dominance when NeX/N eA > 3/4.
We also examined various parameters that are known to influence the rates of evolution
at X-linked and autosomal sites, such as different mutation rates in males and
females and mutations that are sexually antagonistic, to determine which cases
can lead to faster-X evolution. We show that, when the rate of nonsynonymous evolution
is normalized by the rate of neutral evolution, a sex difference in mutation rate
has no influence on the conditions for faster-X evolution.
acknowledgement: This work was funded by a Portuguese Foundation for Science and Technology
scholarship to BV, and BC was supported by the Royal Society
author:
- first_name: Beatriz
full_name: Beatriz Vicoso
id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
last_name: Vicoso
orcid: 0000-0002-4579-8306
- first_name: Brian
full_name: Charlesworth, Brian
last_name: Charlesworth
citation:
ama: 'Vicoso B, Charlesworth B. Effective population size and the faster-X effect:
An extended model. Evolution. 2009;63(9):2413-2426. doi:10.1111/j.1558-5646.2009.00719.x'
apa: 'Vicoso, B., & Charlesworth, B. (2009). Effective population size and the
faster-X effect: An extended model. Evolution. Wiley-Blackwell. https://doi.org/10.1111/j.1558-5646.2009.00719.x'
chicago: 'Vicoso, Beatriz, and Brian Charlesworth. “Effective Population Size and
the Faster-X Effect: An Extended Model.” Evolution. Wiley-Blackwell, 2009.
https://doi.org/10.1111/j.1558-5646.2009.00719.x.'
ieee: 'B. Vicoso and B. Charlesworth, “Effective population size and the faster-X
effect: An extended model,” Evolution, vol. 63, no. 9. Wiley-Blackwell,
pp. 2413–2426, 2009.'
ista: 'Vicoso B, Charlesworth B. 2009. Effective population size and the faster-X
effect: An extended model. Evolution. 63(9), 2413–2426.'
mla: 'Vicoso, Beatriz, and Brian Charlesworth. “Effective Population Size and the
Faster-X Effect: An Extended Model.” Evolution, vol. 63, no. 9, Wiley-Blackwell,
2009, pp. 2413–26, doi:10.1111/j.1558-5646.2009.00719.x.'
short: B. Vicoso, B. Charlesworth, Evolution 63 (2009) 2413–2426.
date_created: 2018-12-11T11:55:32Z
date_published: 2009-09-01T00:00:00Z
date_updated: 2021-01-12T06:55:06Z
day: '01'
doi: 10.1111/j.1558-5646.2009.00719.x
extern: 1
intvolume: ' 63'
issue: '9'
month: '09'
page: 2413 - 2426
publication: Evolution
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4968'
quality_controlled: 0
status: public
title: 'Effective population size and the faster-X effect: An extended model'
type: journal_article
volume: 63
year: '2009'
...
---
_id: '2070'
abstract:
- lang: eng
text: In many eukaryotic organisms, gender is determined by a pair of heteromorphic
sex chromosomes. Degeneration of the non-recombining Y chromosome is a general
facet of sex chromosome evolution. Selective pressure to restore expression levels
of X-linked genes relative to autosomes accompanies Y-chromosome degeneration,
thus driving the evolution of dosage compensation mechanisms. This review focuses
on evolutionary aspects of dosage compensation, in light of recent advances in
comparative and functional genomics that have substantially increased our understanding
of the molecular mechanisms of dosage compensation and how it evolved. We review
processes involved in sex chromosome evolution, and discuss the dynamic interaction
between Y degeneration and the acquisition of dosage compensation. We compare
mechanisms of dosage compensation and the origin of dosage compensation genes
between different taxa and comment on sex chromosomes that apparently lack compensation
mechanisms. Finally, we discuss how dosage compensation systems can also influence
the evolution of well-established sex chromosomes.
acknowledgement: This research is funded by NIH Grant GM076007 and a Sloan Research
Fellowship and a David and Lucile Packard Fellowship to D.B.
author:
- first_name: Beatriz
full_name: Beatriz Vicoso
id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
last_name: Vicoso
orcid: 0000-0002-4579-8306
- first_name: Doris
full_name: Bachtrog, Doris
last_name: Bachtrog
citation:
ama: Vicoso B, Bachtrog D. Progress and prospects toward our understanding of the
evolution of dosage compensation. Chromosome Research. 2009;17(5):585-602.
doi:10.1007/s10577-009-9053-y
apa: Vicoso, B., & Bachtrog, D. (2009). Progress and prospects toward our understanding
of the evolution of dosage compensation. Chromosome Research. Springer.
https://doi.org/10.1007/s10577-009-9053-y
chicago: Vicoso, Beatriz, and Doris Bachtrog. “Progress and Prospects toward Our
Understanding of the Evolution of Dosage Compensation.” Chromosome Research.
Springer, 2009. https://doi.org/10.1007/s10577-009-9053-y.
ieee: B. Vicoso and D. Bachtrog, “Progress and prospects toward our understanding
of the evolution of dosage compensation,” Chromosome Research, vol. 17,
no. 5. Springer, pp. 585–602, 2009.
ista: Vicoso B, Bachtrog D. 2009. Progress and prospects toward our understanding
of the evolution of dosage compensation. Chromosome Research. 17(5), 585–602.
mla: Vicoso, Beatriz, and Doris Bachtrog. “Progress and Prospects toward Our Understanding
of the Evolution of Dosage Compensation.” Chromosome Research, vol. 17,
no. 5, Springer, 2009, pp. 585–602, doi:10.1007/s10577-009-9053-y.
short: B. Vicoso, D. Bachtrog, Chromosome Research 17 (2009) 585–602.
date_created: 2018-12-11T11:55:32Z
date_published: 2009-07-01T00:00:00Z
date_updated: 2021-01-12T06:55:07Z
day: '01'
doi: 10.1007/s10577-009-9053-y
extern: 1
intvolume: ' 17'
issue: '5'
month: '07'
page: 585 - 602
publication: Chromosome Research
publication_status: published
publisher: Springer
publist_id: '4969'
quality_controlled: 0
status: public
title: Progress and prospects toward our understanding of the evolution of dosage
compensation
type: journal_article
volume: 17
year: '2009'
...
---
_id: '1971'
abstract:
- lang: eng
text: Complex I plays a central role in cellular energy production, coupling electron
transfer between NADH and quinone to proton translocation. The mechanism of this
highly efficient enzyme is currently unknown. Mitochondrial complex I is a major
source of reactive oxygen species, which may be one of the causes of aging. Dysfunction
of complex I is implicated in many human neurodegenerative diseases. We have determined
several x-ray structures of the oxidized and reduced hydrophilic domain of complex
I from Thermus thermophilus at up to 3.1 Å resolution. The structures reveal the
mode of interaction of complex I with NADH, explaining known kinetic data and
providing implications for the mechanism of reactive oxygen species production
at the flavin site of complex I. Bound metals were identified in the channel at
the interface with the frataxin-like subunit Nqo15, indicating possible iron-binding
sites. Conformational changes upon reduction of the complex involve adjustments
in the nucleotide-binding pocket, as well as small but significant shifts of several
α-helices at the interface with the membrane domain. These shifts are likely to
be driven by the reduction of nearby iron-sulfur clusters N2 and N6a/b. Cluster
N2 is the electron donor to quinone and is coordinated by unique motif involving
two consecutive (tandem) cysteines. An unprecedented "on/off switch"
(disconnection) of coordinating bonds between the tandem cysteines and this cluster
was observed upon reduction. Comparison of the structures suggests a novel mechanism
of coupling between electron transfer and proton translocation, combining conformational
changes and protonation/deprotonation of tandem cysteines.
acknowledgement: 'This work was supported by the Medical Research Council. '
author:
- first_name: John
full_name: Berrisford, John M
last_name: Berrisford
- first_name: Leonid A
full_name: Leonid Sazanov
id: 338D39FE-F248-11E8-B48F-1D18A9856A87
last_name: Sazanov
orcid: 0000-0002-0977-7989
citation:
ama: Berrisford J, Sazanov LA. Structural basis for the mechanism of respiratory
complex I. Journal of Biological Chemistry. 2009;284(43):29773-29783. doi:10.1074/jbc.M109.032144
apa: Berrisford, J., & Sazanov, L. A. (2009). Structural basis for the mechanism
of respiratory complex I. Journal of Biological Chemistry. American Society
for Biochemistry and Molecular Biology. https://doi.org/10.1074/jbc.M109.032144
chicago: Berrisford, John, and Leonid A Sazanov. “Structural Basis for the Mechanism
of Respiratory Complex I.” Journal of Biological Chemistry. American Society
for Biochemistry and Molecular Biology, 2009. https://doi.org/10.1074/jbc.M109.032144.
ieee: J. Berrisford and L. A. Sazanov, “Structural basis for the mechanism of respiratory
complex I,” Journal of Biological Chemistry, vol. 284, no. 43. American
Society for Biochemistry and Molecular Biology, pp. 29773–29783, 2009.
ista: Berrisford J, Sazanov LA. 2009. Structural basis for the mechanism of respiratory
complex I. Journal of Biological Chemistry. 284(43), 29773–29783.
mla: Berrisford, John, and Leonid A. Sazanov. “Structural Basis for the Mechanism
of Respiratory Complex I.” Journal of Biological Chemistry, vol. 284, no.
43, American Society for Biochemistry and Molecular Biology, 2009, pp. 29773–83,
doi:10.1074/jbc.M109.032144.
short: J. Berrisford, L.A. Sazanov, Journal of Biological Chemistry 284 (2009) 29773–29783.
date_created: 2018-12-11T11:54:59Z
date_published: 2009-10-23T00:00:00Z
date_updated: 2021-01-12T06:54:26Z
day: '23'
doi: 10.1074/jbc.M109.032144
extern: 1
intvolume: ' 284'
issue: '43'
month: '10'
page: 29773 - 29783
publication: Journal of Biological Chemistry
publication_status: published
publisher: American Society for Biochemistry and Molecular Biology
publist_id: '5114'
quality_controlled: 0
status: public
title: Structural basis for the mechanism of respiratory complex I
type: journal_article
volume: 284
year: '2009'
...
---
_id: '110'
abstract:
- lang: eng
text: In order to better understand magnetic reconnection and particle acceleration
in solar flares, we compare the RHESSI hard X-ray (HXR) footpoint motions of three
flares with a detailed study of the corresponding topology given by a Magnetic
Charge Topology model. We analyze the relationship between the footpoint motions
and topological spine lines and find that the examined footpoint sources move
along spine lines. We present a three-dimensional topological model in which this
movement can be understood. As reconnection proceeds, flux is transferred between
the reconnecting domains, causing the separator to move. The movement of the separator\'s
chromospheric ends, identified with the HXR footpoints, is along those spine lines
on which the separator ends.
acknowledgement: This work was supported by RHESSI funds from the University of California
at Berkeley through a contract, SA1868-26308PG, with Montana State University. Funding
for our Research Experience for Undergraduates (REU) students was provided by NSF
grant ATM-0243923.
author:
- first_name: Angela
full_name: Des Jardins, Angela
last_name: Des Jardins
- first_name: Richard
full_name: Canfield, Richard
last_name: Canfield
- first_name: Dana
full_name: Longcope, Dana
last_name: Longcope
- first_name: Crystal
full_name: Fordyce, Crystal
last_name: Fordyce
- first_name: Scott R
full_name: Waitukaitis, Scott R
id: 3A1FFC16-F248-11E8-B48F-1D18A9856A87
last_name: Waitukaitis
orcid: 0000-0002-2299-3176
citation:
ama: 'Des Jardins A, Canfield R, Longcope D, Fordyce C, Waitukaitis SR. Reconnection
in three dimensions: The role of spines in three eruptive flares. The Astrophysical
Journal. 2009;693(2):1628-1636. doi:10.1088/0004-637X/693/2/1628'
apa: 'Des Jardins, A., Canfield, R., Longcope, D., Fordyce, C., & Waitukaitis,
S. R. (2009). Reconnection in three dimensions: The role of spines in three eruptive
flares. The Astrophysical Journal. IOP Publishing Ltd. https://doi.org/10.1088/0004-637X/693/2/1628'
chicago: 'Des Jardins, Angela, Richard Canfield, Dana Longcope, Crystal Fordyce,
and Scott R Waitukaitis. “Reconnection in Three Dimensions: The Role of Spines
in Three Eruptive Flares.” The Astrophysical Journal. IOP Publishing Ltd.,
2009. https://doi.org/10.1088/0004-637X/693/2/1628.'
ieee: 'A. Des Jardins, R. Canfield, D. Longcope, C. Fordyce, and S. R. Waitukaitis,
“Reconnection in three dimensions: The role of spines in three eruptive flares,”
The Astrophysical Journal, vol. 693, no. 2. IOP Publishing Ltd., pp. 1628–1636,
2009.'
ista: 'Des Jardins A, Canfield R, Longcope D, Fordyce C, Waitukaitis SR. 2009. Reconnection
in three dimensions: The role of spines in three eruptive flares. The Astrophysical
Journal. 693(2), 1628–1636.'
mla: 'Des Jardins, Angela, et al. “Reconnection in Three Dimensions: The Role of
Spines in Three Eruptive Flares.” The Astrophysical Journal, vol. 693,
no. 2, IOP Publishing Ltd., 2009, pp. 1628–36, doi:10.1088/0004-637X/693/2/1628.'
short: A. Des Jardins, R. Canfield, D. Longcope, C. Fordyce, S.R. Waitukaitis, The
Astrophysical Journal 693 (2009) 1628–1636.
date_created: 2018-12-11T11:44:41Z
date_published: 2009-03-10T00:00:00Z
date_updated: 2021-01-12T06:48:16Z
day: '10'
doi: 10.1088/0004-637X/693/2/1628
extern: '1'
intvolume: ' 693'
issue: '2'
language:
- iso: eng
month: '03'
oa_version: None
page: 1628 - 1636
publication: The Astrophysical Journal
publication_status: published
publisher: IOP Publishing Ltd.
publist_id: '7944'
quality_controlled: '1'
status: public
title: 'Reconnection in three dimensions: The role of spines in three eruptive flares'
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 693
year: '2009'
...
---
_id: '111'
abstract:
- lang: eng
text: Thin streams of liquid commonly break up into characteristic droplet patterns
owing to the surface-tension-driven PlateauRayleigh instability 1-3. Very similar
patterns are observed when initially uniform streams of dry granular material
break up into clusters of grains4-6, even though flows of macroscopic particles
are considered to lack surface tension7,8. Recent studies on freely falling granular
streams tracked fluctuations in the stream profile9, but the clustering mechanism
remained unresolved because the full evolution of the instability could not be
observed. Here we demonstrate that the cluster formation is driven by minute,
nanoNewton cohesive forces that arise from a combination of van der Waals interactions
and capillary bridges between nanometre-scale surface asperities. Our experiments
involve high-speed video imaging of the granular stream in the co-moving frame,
control over the properties of the grain surfaces and the use of atomic force
microscopy to measure grain-grain interactions. The cohesive forces that we measure
correspond to an equivalent surface tension five orders of magnitude below that,
of ordinary liquids. We find that, the shapes of these weakly cohesive, non-thermal
clusters of macroscopic particles closely resemble droplets resulting from thermally
induced rupture of liquid nanojets 10-12.
acknowledgement: This work was supported by NSF through its MRSEC programme and the
Inter-American Materials Collaboration Chicago-Chile, and by the Keck Initiative
for Ultrafast Imaging at the University of Chicago.
author:
- first_name: John
full_name: Royer, John
last_name: Royer
- first_name: Daniel
full_name: Evans, Daniel
last_name: Evans
- first_name: Loreto
full_name: Oyarte, Loreto
last_name: Oyarte
- first_name: Qiti
full_name: Guo, Qiti
last_name: Guo
- first_name: Eliot
full_name: Kapit, Eliot
last_name: Kapit
- first_name: Matthias
full_name: Möbius, Matthias
last_name: Möbius
- first_name: Scott R
full_name: Waitukaitis, Scott R
id: 3A1FFC16-F248-11E8-B48F-1D18A9856A87
last_name: Waitukaitis
orcid: 0000-0002-2299-3176
- first_name: Heinrich
full_name: Jaeger, Heinrich
last_name: Jaeger
citation:
ama: Royer J, Evans D, Oyarte L, et al. High-speed tracking of rupture and clustering
in freely falling granular streams. Nature. 2009;459(7250):1110-1113. doi:10.1038/nature08115
apa: Royer, J., Evans, D., Oyarte, L., Guo, Q., Kapit, E., Möbius, M., … Jaeger,
H. (2009). High-speed tracking of rupture and clustering in freely falling granular
streams. Nature. Nature Publishing Group. https://doi.org/10.1038/nature08115
chicago: Royer, John, Daniel Evans, Loreto Oyarte, Qiti Guo, Eliot Kapit, Matthias
Möbius, Scott R Waitukaitis, and Heinrich Jaeger. “High-Speed Tracking of Rupture
and Clustering in Freely Falling Granular Streams.” Nature. Nature Publishing
Group, 2009. https://doi.org/10.1038/nature08115.
ieee: J. Royer et al., “High-speed tracking of rupture and clustering in
freely falling granular streams,” Nature, vol. 459, no. 7250. Nature Publishing
Group, pp. 1110–1113, 2009.
ista: Royer J, Evans D, Oyarte L, Guo Q, Kapit E, Möbius M, Waitukaitis SR, Jaeger
H. 2009. High-speed tracking of rupture and clustering in freely falling granular
streams. Nature. 459(7250), 1110–1113.
mla: Royer, John, et al. “High-Speed Tracking of Rupture and Clustering in Freely
Falling Granular Streams.” Nature, vol. 459, no. 7250, Nature Publishing
Group, 2009, pp. 1110–13, doi:10.1038/nature08115.
short: J. Royer, D. Evans, L. Oyarte, Q. Guo, E. Kapit, M. Möbius, S.R. Waitukaitis,
H. Jaeger, Nature 459 (2009) 1110–1113.
date_created: 2018-12-11T11:44:41Z
date_published: 2009-06-25T00:00:00Z
date_updated: 2021-01-12T06:48:21Z
day: '25'
doi: 10.1038/nature08115
extern: '1'
intvolume: ' 459'
issue: '7250'
language:
- iso: eng
month: '06'
oa_version: None
page: 1110 - 1113
publication: Nature
publication_status: published
publisher: Nature Publishing Group
publist_id: '7943'
quality_controlled: '1'
status: public
title: High-speed tracking of rupture and clustering in freely falling granular streams
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 459
year: '2009'
...
---
_id: '11103'
abstract:
- lang: eng
text: Over the last decade, the nuclear envelope (NE) has emerged as a key component
in the organization and function of the nuclear genome. As many as 100 different
proteins are thought to specifically localize to this double membrane that separates
the cytoplasm and the nucleoplasm of eukaryotic cells. Selective portals through
the NE are formed at sites where the inner and outer nuclear membranes are fused,
and the coincident assembly of ∼30 proteins into nuclear pore complexes occurs.
These nuclear pore complexes are essential for the control of nucleocytoplasmic
exchange. Many of the NE and nuclear pore proteins are thought to play crucial
roles in gene regulation and thus are increasingly linked to human diseases.
article_processing_charge: No
article_type: review
author:
- first_name: Martin W
full_name: HETZER, Martin W
id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
last_name: HETZER
orcid: 0000-0002-2111-992X
- first_name: Susan R.
full_name: Wente, Susan R.
last_name: Wente
citation:
ama: 'Hetzer M, Wente SR. Border control at the nucleus: Biogenesis and organization
of the nuclear membrane and pore complexes. Developmental Cell. 2009;17(5):606-616.
doi:10.1016/j.devcel.2009.10.007'
apa: 'Hetzer, M., & Wente, S. R. (2009). Border control at the nucleus: Biogenesis
and organization of the nuclear membrane and pore complexes. Developmental
Cell. Elsevier. https://doi.org/10.1016/j.devcel.2009.10.007'
chicago: 'Hetzer, Martin, and Susan R. Wente. “Border Control at the Nucleus: Biogenesis
and Organization of the Nuclear Membrane and Pore Complexes.” Developmental
Cell. Elsevier, 2009. https://doi.org/10.1016/j.devcel.2009.10.007.'
ieee: 'M. Hetzer and S. R. Wente, “Border control at the nucleus: Biogenesis and
organization of the nuclear membrane and pore complexes,” Developmental Cell,
vol. 17, no. 5. Elsevier, pp. 606–616, 2009.'
ista: 'Hetzer M, Wente SR. 2009. Border control at the nucleus: Biogenesis and organization
of the nuclear membrane and pore complexes. Developmental Cell. 17(5), 606–616.'
mla: 'Hetzer, Martin, and Susan R. Wente. “Border Control at the Nucleus: Biogenesis
and Organization of the Nuclear Membrane and Pore Complexes.” Developmental
Cell, vol. 17, no. 5, Elsevier, 2009, pp. 606–16, doi:10.1016/j.devcel.2009.10.007.'
short: M. Hetzer, S.R. Wente, Developmental Cell 17 (2009) 606–616.
date_created: 2022-04-07T07:53:45Z
date_published: 2009-11-17T00:00:00Z
date_updated: 2024-10-14T11:28:25Z
day: '17'
doi: 10.1016/j.devcel.2009.10.007
extern: '1'
external_id:
pmid:
- '19922866'
intvolume: ' 17'
issue: '5'
keyword:
- Developmental Biology
- Cell Biology
- General Biochemistry
- Genetics and Molecular Biology
- Molecular Biology
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.devcel.2009.10.007
month: '11'
oa: 1
oa_version: Published Version
page: 606-616
pmid: 1
publication: Developmental Cell
publication_identifier:
issn:
- 1534-5807
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Border control at the nucleus: Biogenesis and organization of the nuclear
membrane and pore complexes'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2009'
...
---
_id: '11105'
abstract:
- lang: eng
text: Nuclear-pore complexes (NPCs) are large protein channels that span the nuclear
envelope (NE), which is a double membrane that encloses the nuclear genome of
eukaryotes. Each of the typically 2,000–4,000 pores in the NE of vertebrate cells
is composed of multiple copies of 30 different proteins known as nucleoporins.
The evolutionarily conserved NPC proteins have the well-characterized function
of mediating the transport of molecules between the nucleoplasm and the cytoplasm.
Mutations in nucleoporins are often linked to specific developmental defects and
disease, and the resulting phenotypes are usually interpreted as the consequences
of perturbed nuclear transport activity. However, recent evidence suggests that
NPCs have additional functions in chromatin organization and gene regulation,
some of which might be independent of nuclear transport. Here, we review the transport-dependent
and transport-independent roles of NPCs in the regulation of nuclear function
and gene expression.
article_processing_charge: No
article_type: original
author:
- first_name: Maya
full_name: Capelson, Maya
last_name: Capelson
- first_name: Martin W
full_name: HETZER, Martin W
id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
last_name: HETZER
orcid: 0000-0002-2111-992X
citation:
ama: Capelson M, Hetzer M. The role of nuclear pores in gene regulation, development
and disease. EMBO reports. 2009;10(7):697-705. doi:10.1038/embor.2009.147
apa: Capelson, M., & Hetzer, M. (2009). The role of nuclear pores in gene regulation,
development and disease. EMBO Reports. EMBO. https://doi.org/10.1038/embor.2009.147
chicago: Capelson, Maya, and Martin Hetzer. “The Role of Nuclear Pores in Gene Regulation,
Development and Disease.” EMBO Reports. EMBO, 2009. https://doi.org/10.1038/embor.2009.147.
ieee: M. Capelson and M. Hetzer, “The role of nuclear pores in gene regulation,
development and disease,” EMBO reports, vol. 10, no. 7. EMBO, pp. 697–705,
2009.
ista: Capelson M, Hetzer M. 2009. The role of nuclear pores in gene regulation,
development and disease. EMBO reports. 10(7), 697–705.
mla: Capelson, Maya, and Martin Hetzer. “The Role of Nuclear Pores in Gene Regulation,
Development and Disease.” EMBO Reports, vol. 10, no. 7, EMBO, 2009, pp.
697–705, doi:10.1038/embor.2009.147.
short: M. Capelson, M. Hetzer, EMBO Reports 10 (2009) 697–705.
date_created: 2022-04-07T07:54:06Z
date_published: 2009-07-01T00:00:00Z
date_updated: 2024-10-14T11:28:35Z
day: '01'
doi: 10.1038/embor.2009.147
extern: '1'
external_id:
pmid:
- '19543230'
intvolume: ' 10'
issue: '7'
keyword:
- Genetics
- Molecular Biology
- Biochemistry
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1038/embor.2009.147
month: '07'
oa: 1
oa_version: Published Version
page: 697-705
pmid: 1
publication: EMBO reports
publication_identifier:
eissn:
- 1469-3178
issn:
- 1469-221X
publication_status: published
publisher: EMBO
quality_controlled: '1'
related_material:
link:
- relation: erratum
url: https://doi.org/10.1038/embor.2009.176
scopus_import: '1'
status: public
title: The role of nuclear pores in gene regulation, development and disease
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10
year: '2009'
...
---
_id: '11106'
abstract:
- lang: eng
text: Formation of the nuclear envelope (NE) around segregated chromosomes occurs
by the reshaping of the endoplasmic reticulum (ER), a reservoir for disassembled
nuclear membrane components during mitosis. In this study, we show that inner
nuclear membrane proteins such as lamin B receptor (LBR), MAN1, Lap2β, and the
trans-membrane nucleoporins Ndc1 and POM121 drive the spreading of ER membranes
into the emerging NE via their capacity to bind chromatin in a collaborative manner.
Despite their redundant functions, decreasing the levels of any of these trans-membrane
proteins by RNAi-mediated knockdown delayed NE formation, whereas increasing the
levels of any of them had the opposite effect. Furthermore, acceleration of NE
formation interferes with chromosome separation during mitosis, indicating that
the time frame over which chromatin becomes membrane enclosed is physiologically
relevant and regulated. These data suggest that functionally distinct classes
of chromatin-interacting membrane proteins, which are present at nonsaturating
levels, collaborate to rapidly reestablish the nuclear compartment at the end
of mitosis.
article_processing_charge: No
article_type: original
author:
- first_name: Daniel J.
full_name: Anderson, Daniel J.
last_name: Anderson
- first_name: Jesse D.
full_name: Vargas, Jesse D.
last_name: Vargas
- first_name: Joshua P.
full_name: Hsiao, Joshua P.
last_name: Hsiao
- first_name: Martin W
full_name: HETZER, Martin W
id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
last_name: HETZER
orcid: 0000-0002-2111-992X
citation:
ama: Anderson DJ, Vargas JD, Hsiao JP, Hetzer M. Recruitment of functionally distinct
membrane proteins to chromatin mediates nuclear envelope formation in vivo. Journal
of Cell Biology. 2009;186(2):183-191. doi:10.1083/jcb.200901106
apa: Anderson, D. J., Vargas, J. D., Hsiao, J. P., & Hetzer, M. (2009). Recruitment
of functionally distinct membrane proteins to chromatin mediates nuclear envelope
formation in vivo. Journal of Cell Biology. Rockefeller University Press.
https://doi.org/10.1083/jcb.200901106
chicago: Anderson, Daniel J., Jesse D. Vargas, Joshua P. Hsiao, and Martin Hetzer.
“Recruitment of Functionally Distinct Membrane Proteins to Chromatin Mediates
Nuclear Envelope Formation in Vivo.” Journal of Cell Biology. Rockefeller
University Press, 2009. https://doi.org/10.1083/jcb.200901106.
ieee: D. J. Anderson, J. D. Vargas, J. P. Hsiao, and M. Hetzer, “Recruitment of
functionally distinct membrane proteins to chromatin mediates nuclear envelope
formation in vivo,” Journal of Cell Biology, vol. 186, no. 2. Rockefeller
University Press, pp. 183–191, 2009.
ista: Anderson DJ, Vargas JD, Hsiao JP, Hetzer M. 2009. Recruitment of functionally
distinct membrane proteins to chromatin mediates nuclear envelope formation in
vivo. Journal of Cell Biology. 186(2), 183–191.
mla: Anderson, Daniel J., et al. “Recruitment of Functionally Distinct Membrane
Proteins to Chromatin Mediates Nuclear Envelope Formation in Vivo.” Journal
of Cell Biology, vol. 186, no. 2, Rockefeller University Press, 2009, pp.
183–91, doi:10.1083/jcb.200901106.
short: D.J. Anderson, J.D. Vargas, J.P. Hsiao, M. Hetzer, Journal of Cell Biology
186 (2009) 183–191.
date_created: 2022-04-07T07:54:18Z
date_published: 2009-07-20T00:00:00Z
date_updated: 2024-10-14T11:28:48Z
day: '20'
doi: 10.1083/jcb.200901106
extern: '1'
external_id:
pmid:
- '19620630'
intvolume: ' 186'
issue: '2'
keyword:
- Cell Biology
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1083/jcb.200901106
month: '07'
oa: 1
oa_version: Published Version
page: 183-191
pmid: 1
publication: Journal of Cell Biology
publication_identifier:
eissn:
- 1540-8140
issn:
- 0021-9525
publication_status: published
publisher: Rockefeller University Press
quality_controlled: '1'
related_material:
link:
- relation: erratum
url: https://doi.org/10.1083/jcb.20090110620090903c
scopus_import: '1'
status: public
title: Recruitment of functionally distinct membrane proteins to chromatin mediates
nuclear envelope formation in vivo
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 186
year: '2009'
...
---
_id: '11107'
abstract:
- lang: eng
text: Nucleocytoplasmic transport occurs exclusively through nuclear pore complexes
(NPCs) embedded in pores formed by inner and outer nuclear membrane fusion. The
mechanism for de novo pore and NPC biogenesis remains unclear. Reticulons (RTNs)
and Yop1/DP1 are conserved membrane protein families required to form and maintain
the tubular endoplasmic reticulum (ER) and the postmitotic nuclear envelope. In
this study, we report that members of the RTN and Yop1/DP1 families are required
for nuclear pore formation. Analysis of Saccharomyces cerevisiae prp20-G282S and
nup133Δ NPC assembly mutants revealed perturbations in Rtn1–green fluorescent
protein (GFP) and Yop1-GFP ER distribution and colocalization to NPC clusters.
Combined deletion of RTN1 and YOP1 resulted in NPC clustering, nuclear import
defects, and synthetic lethality with the additional absence of Pom34, Pom152,
and Nup84 subcomplex members. We tested for a direct role in NPC biogenesis using
Xenopus laevis in vitro assays and found that anti-Rtn4a antibodies specifically
inhibited de novo nuclear pore formation. We hypothesize that these ER membrane–bending
proteins mediate early NPC assembly steps.
article_processing_charge: No
article_type: original
author:
- first_name: T. Renee
full_name: Dawson, T. Renee
last_name: Dawson
- first_name: Michelle D.
full_name: Lazarus, Michelle D.
last_name: Lazarus
- first_name: Martin W
full_name: HETZER, Martin W
id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
last_name: HETZER
orcid: 0000-0002-2111-992X
- first_name: Susan R.
full_name: Wente, Susan R.
last_name: Wente
citation:
ama: Dawson TR, Lazarus MD, Hetzer M, Wente SR. ER membrane–bending proteins are
necessary for de novo nuclear pore formation. Journal of Cell Biology.
2009;184(5):659-675. doi:10.1083/jcb.200806174
apa: Dawson, T. R., Lazarus, M. D., Hetzer, M., & Wente, S. R. (2009). ER membrane–bending
proteins are necessary for de novo nuclear pore formation. Journal of Cell
Biology. Rockefeller University Press. https://doi.org/10.1083/jcb.200806174
chicago: Dawson, T. Renee, Michelle D. Lazarus, Martin Hetzer, and Susan R. Wente.
“ER Membrane–Bending Proteins Are Necessary for de Novo Nuclear Pore Formation.”
Journal of Cell Biology. Rockefeller University Press, 2009. https://doi.org/10.1083/jcb.200806174.
ieee: T. R. Dawson, M. D. Lazarus, M. Hetzer, and S. R. Wente, “ER membrane–bending
proteins are necessary for de novo nuclear pore formation,” Journal of Cell
Biology, vol. 184, no. 5. Rockefeller University Press, pp. 659–675, 2009.
ista: Dawson TR, Lazarus MD, Hetzer M, Wente SR. 2009. ER membrane–bending proteins
are necessary for de novo nuclear pore formation. Journal of Cell Biology. 184(5),
659–675.
mla: Dawson, T. Renee, et al. “ER Membrane–Bending Proteins Are Necessary for de
Novo Nuclear Pore Formation.” Journal of Cell Biology, vol. 184, no. 5,
Rockefeller University Press, 2009, pp. 659–75, doi:10.1083/jcb.200806174.
short: T.R. Dawson, M.D. Lazarus, M. Hetzer, S.R. Wente, Journal of Cell Biology
184 (2009) 659–675.
date_created: 2022-04-07T07:54:44Z
date_published: 2009-03-09T00:00:00Z
date_updated: 2022-07-18T08:55:05Z
day: '09'
doi: 10.1083/jcb.200806174
extern: '1'
external_id:
pmid:
- '19273614'
intvolume: ' 184'
issue: '5'
keyword:
- Cell Biology
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1083/jcb.200806174
month: '03'
oa: 1
oa_version: Published Version
page: 659-675
pmid: 1
publication: Journal of Cell Biology
publication_identifier:
eissn:
- 1540-8140
issn:
- 0021-9525
publication_status: published
publisher: Rockefeller University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: ER membrane–bending proteins are necessary for de novo nuclear pore formation
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 184
year: '2009'
...
---
_id: '11108'
abstract:
- lang: eng
text: In dividing cells, nuclear pore complexes (NPCs) disassemble during mitosis
and reassemble into the newly forming nuclei. However, the fate of nuclear pores
in postmitotic cells is unknown. Here, we show that NPCs, unlike other nuclear
structures, do not turn over in differentiated cells. While a subset of NPC components,
like Nup153 and Nup50, are continuously exchanged, scaffold nucleoporins, like
the Nup107/160 complex, are extremely long-lived and remain incorporated in the
nuclear membrane during the entire cellular life span. Besides the lack of nucleoporin
expression and NPC turnover, we discovered an age-related deterioration of NPCs,
leading to an increase in nuclear permeability and the leaking of cytoplasmic
proteins into the nucleus. Our finding that nuclear “leakiness” is dramatically
accelerated during aging and that a subset of nucleoporins is oxidatively damaged
in old cells suggests that the accumulation of damage at the NPC might be a crucial
aging event.
article_processing_charge: No
article_type: original
author:
- first_name: Maximiliano A.
full_name: D'Angelo, Maximiliano A.
last_name: D'Angelo
- first_name: Marcela
full_name: Raices, Marcela
last_name: Raices
- first_name: Siler H.
full_name: Panowski, Siler H.
last_name: Panowski
- first_name: Martin W
full_name: HETZER, Martin W
id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
last_name: HETZER
orcid: 0000-0002-2111-992X
citation:
ama: D’Angelo MA, Raices M, Panowski SH, Hetzer M. Age-dependent deterioration of
nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells.
Cell. 2009;136(2):284-295. doi:10.1016/j.cell.2008.11.037
apa: D’Angelo, M. A., Raices, M., Panowski, S. H., & Hetzer, M. (2009). Age-dependent
deterioration of nuclear pore complexes causes a loss of nuclear integrity in
postmitotic cells. Cell. Elsevier. https://doi.org/10.1016/j.cell.2008.11.037
chicago: D’Angelo, Maximiliano A., Marcela Raices, Siler H. Panowski, and Martin
Hetzer. “Age-Dependent Deterioration of Nuclear Pore Complexes Causes a Loss of
Nuclear Integrity in Postmitotic Cells.” Cell. Elsevier, 2009. https://doi.org/10.1016/j.cell.2008.11.037.
ieee: M. A. D’Angelo, M. Raices, S. H. Panowski, and M. Hetzer, “Age-dependent deterioration
of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells,”
Cell, vol. 136, no. 2. Elsevier, pp. 284–295, 2009.
ista: D’Angelo MA, Raices M, Panowski SH, Hetzer M. 2009. Age-dependent deterioration
of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells.
Cell. 136(2), 284–295.
mla: D’Angelo, Maximiliano A., et al. “Age-Dependent Deterioration of Nuclear Pore
Complexes Causes a Loss of Nuclear Integrity in Postmitotic Cells.” Cell,
vol. 136, no. 2, Elsevier, 2009, pp. 284–95, doi:10.1016/j.cell.2008.11.037.
short: M.A. D’Angelo, M. Raices, S.H. Panowski, M. Hetzer, Cell 136 (2009) 284–295.
date_created: 2022-04-07T07:54:52Z
date_published: 2009-01-23T00:00:00Z
date_updated: 2024-10-14T11:28:59Z
day: '23'
doi: 10.1016/j.cell.2008.11.037
extern: '1'
external_id:
pmid:
- '19167330'
intvolume: ' 136'
issue: '2'
keyword:
- General Biochemistry
- Genetics and Molecular Biology
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.cell.2008.11.037
month: '01'
oa: 1
oa_version: Published Version
page: 284-295
pmid: 1
publication: Cell
publication_identifier:
issn:
- 0092-8674
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Age-dependent deterioration of nuclear pore complexes causes a loss of nuclear
integrity in postmitotic cells
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 136
year: '2009'
...
---
_id: '1038'
abstract:
- lang: eng
text: One possible way to produce ultra-cold, high-phase-space-density quantum gases
of molecules in the rovibronic ground state is given by molecule association from
quantum-degenerate atomic gases on a Feshbach resonance and subsequent coherent
optical multi-photon transfer into the rovibronic ground state. In ultra-cold
samples of Cs2 molecules, we observe two-photon dark resonances that connect the
intermediate rovibrational level |v=73,J=2 with the rovibrational ground state
|v=0,J=0 of the singlet X 1 ∑ g + ground-state potential. For precise dark resonance
spectroscopy we exploit the fact that it is possible to efficiently populate the
level |v=73,J=2 by two-photon transfer from the dissociation threshold with the
stimulated Raman adiabatic passage (STIRAP) technique. We find that at least one
of the two-photon resonances is sufficiently strong to allow future implementation
of coherent STIRAP transfer of a molecular quantum gas to the rovibrational ground
state |v=0,J=0.
acknowledgement: "We are indebted to R. Grimm for generous support and we thank E.
Tiemann for valuable discussions and C. Amiot for providing the FTS data of LAC
on Cs2. We gratefully acknowledge funding by the Austrian Ministry of Science and
Research (BMWF)\r\nand the Austrian Science Fund (FWF) in the form of a START prize
grant and by the European Science Foundation (ESF) in the framework of the EuroQUAM
collective research project QuDipMol. R.H. acknowledges support by the European
Union in the form of a Marie Curie International Incoming Fellowship (IIF). The
work at Stony Brook was supported by the US NSF, under grant PHY0652459."
article_processing_charge: No
arxiv: 1
author:
- first_name: Manfred
full_name: Mark, Manfred
last_name: Mark
- first_name: Johann G
full_name: Danzl, Johann G
id: 42EFD3B6-F248-11E8-B48F-1D18A9856A87
last_name: Danzl
orcid: 0000-0001-8559-3973
- first_name: Elmar
full_name: Haller, Elmar
last_name: Haller
- first_name: Mattias
full_name: Gustavsson, Mattias
last_name: Gustavsson
- first_name: Nadia
full_name: Bouloufa, Nadia
last_name: Bouloufa
- first_name: Olivier
full_name: Dulieu, Olivier
last_name: Dulieu
- first_name: Houssam
full_name: Salami, Houssam
last_name: Salami
- first_name: Thomas
full_name: Bergeman, Thomas
last_name: Bergeman
- first_name: Helmut
full_name: Ritsch, Helmut
last_name: Ritsch
- first_name: Russell
full_name: Hart, Russell
last_name: Hart
- first_name: Hanns
full_name: Nägerl, Hanns
last_name: Nägerl
citation:
ama: 'Mark M, Danzl JG, Haller E, et al. Dark resonances for ground-state transfer
of molecular quantum gases. Applied Physics B: Lasers and Optics. 2009;95(2):219-225.
doi:10.1007/s00340-009-3407-1'
apa: 'Mark, M., Danzl, J. G., Haller, E., Gustavsson, M., Bouloufa, N., Dulieu,
O., … Nägerl, H. (2009). Dark resonances for ground-state transfer of molecular
quantum gases. Applied Physics B: Lasers and Optics. Springer. https://doi.org/10.1007/s00340-009-3407-1'
chicago: 'Mark, Manfred, Johann G Danzl, Elmar Haller, Mattias Gustavsson, Nadia
Bouloufa, Olivier Dulieu, Houssam Salami, et al. “Dark Resonances for Ground-State
Transfer of Molecular Quantum Gases.” Applied Physics B: Lasers and Optics.
Springer, 2009. https://doi.org/10.1007/s00340-009-3407-1.'
ieee: 'M. Mark et al., “Dark resonances for ground-state transfer of molecular
quantum gases,” Applied Physics B: Lasers and Optics, vol. 95, no. 2. Springer,
pp. 219–225, 2009.'
ista: 'Mark M, Danzl JG, Haller E, Gustavsson M, Bouloufa N, Dulieu O, Salami H,
Bergeman T, Ritsch H, Hart R, Nägerl H. 2009. Dark resonances for ground-state
transfer of molecular quantum gases. Applied Physics B: Lasers and Optics. 95(2),
219–225.'
mla: 'Mark, Manfred, et al. “Dark Resonances for Ground-State Transfer of Molecular
Quantum Gases.” Applied Physics B: Lasers and Optics, vol. 95, no. 2, Springer,
2009, pp. 219–25, doi:10.1007/s00340-009-3407-1.'
short: 'M. Mark, J.G. Danzl, E. Haller, M. Gustavsson, N. Bouloufa, O. Dulieu, H.
Salami, T. Bergeman, H. Ritsch, R. Hart, H. Nägerl, Applied Physics B: Lasers
and Optics 95 (2009) 219–225.'
date_created: 2018-12-11T11:49:49Z
date_published: 2009-05-01T00:00:00Z
date_updated: 2021-01-12T06:47:50Z
day: '01'
doi: 10.1007/s00340-009-3407-1
extern: '1'
external_id:
arxiv:
- '0811.0695'
intvolume: ' 95'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/0811.0695
month: '05'
oa: 1
oa_version: None
page: 219 - 225
publication: 'Applied Physics B: Lasers and Optics'
publication_status: published
publisher: Springer
publist_id: '6350'
status: public
title: Dark resonances for ground-state transfer of molecular quantum gases
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 95
year: '2009'
...