---
_id: '1299'
abstract:
- lang: eng
  text: Recent experiments have shown that motion detection in Drosophila starts with
    splitting the visual input into two parallel channels encoding brightness increments
    (ON) or decrements (OFF). This suggests the existence of either two (ON-ON, OFF-OFF)
    or four (for all pairwise interactions) separate motion detectors. To decide between
    these possibilities, we stimulated flies using sequences of ON and OFF brightness
    pulses while recording from motion-sensitive tangential cells. We found direction-selective
    responses to sequences of same sign (ON-ON, OFF-OFF), but not of opposite sign
    (ON-OFF, OFF-ON), refuting the existence of four separate detectors. Based on
    further measurements, we propose a model that reproduces a variety of additional
    experimental data sets, including ones that were previously interpreted as support
    for four separate detectors. Our experiments and the derived model mark an important
    step in guiding further dissection of the fly motion detection circuit.
author:
- first_name: Hubert
  full_name: Eichner, Hubert
  last_name: Eichner
- first_name: Maximilian A
  full_name: Maximilian Jösch
  id: 2BD278E6-F248-11E8-B48F-1D18A9856A87
  last_name: Jösch
  orcid: 0000-0002-3937-1330
- first_name: Bettina
  full_name: Schnell, Bettina
  last_name: Schnell
- first_name: Dierk
  full_name: Reiff, Dierk F
  last_name: Reiff
- first_name: Alexander
  full_name: Borst, Alexander
  last_name: Borst
citation:
  ama: Eichner H, Jösch MA, Schnell B, Reiff D, Borst A. Internal structure of the
    fly elementary motion detector. <i>Neuron</i>. 2011;70(6):1155-1164. doi:<a href="https://doi.org/10.1016/j.neuron.2011.03.028">10.1016/j.neuron.2011.03.028</a>
  apa: Eichner, H., Jösch, M. A., Schnell, B., Reiff, D., &#38; Borst, A. (2011).
    Internal structure of the fly elementary motion detector. <i>Neuron</i>. Elsevier.
    <a href="https://doi.org/10.1016/j.neuron.2011.03.028">https://doi.org/10.1016/j.neuron.2011.03.028</a>
  chicago: Eichner, Hubert, Maximilian A Jösch, Bettina Schnell, Dierk Reiff, and
    Alexander Borst. “Internal Structure of the Fly Elementary Motion Detector.” <i>Neuron</i>.
    Elsevier, 2011. <a href="https://doi.org/10.1016/j.neuron.2011.03.028">https://doi.org/10.1016/j.neuron.2011.03.028</a>.
  ieee: H. Eichner, M. A. Jösch, B. Schnell, D. Reiff, and A. Borst, “Internal structure
    of the fly elementary motion detector,” <i>Neuron</i>, vol. 70, no. 6. Elsevier,
    pp. 1155–1164, 2011.
  ista: Eichner H, Jösch MA, Schnell B, Reiff D, Borst A. 2011. Internal structure
    of the fly elementary motion detector. Neuron. 70(6), 1155–1164.
  mla: Eichner, Hubert, et al. “Internal Structure of the Fly Elementary Motion Detector.”
    <i>Neuron</i>, vol. 70, no. 6, Elsevier, 2011, pp. 1155–64, doi:<a href="https://doi.org/10.1016/j.neuron.2011.03.028">10.1016/j.neuron.2011.03.028</a>.
  short: H. Eichner, M.A. Jösch, B. Schnell, D. Reiff, A. Borst, Neuron 70 (2011)
    1155–1164.
date_created: 2018-12-11T11:51:14Z
date_published: 2011-06-23T00:00:00Z
date_updated: 2021-01-12T06:49:43Z
day: '23'
doi: 10.1016/j.neuron.2011.03.028
extern: 1
intvolume: '        70'
issue: '6'
month: '06'
page: 1155 - 1164
publication: Neuron
publication_status: published
publisher: Elsevier
publist_id: '5969'
quality_controlled: 0
status: public
title: Internal structure of the fly elementary motion detector
type: journal_article
volume: 70
year: '2011'
...
---
_id: '2098'
abstract:
- lang: eng
  text: This chapter presents a method for real-time animation of highly detailed
    facial expressions based on sparse motion captures data and a limited set of static
    example poses. The method for real-time animation of highly detailed facial expressions
    decomposes geometry into large-scale motion and fine-scale details, such as expression
    wrinkles. Both large- and fine-scale deformation algorithms run entirely on the
    GPU, and our implementation based on CUDA achieves an overall performance of about
    30 fps. The face conveys the most relevant visual characteristics of human identity
    and expression. Hence, realistic facial animations or interactions with virtual
    avatars are important for storytelling and gameplay. However, current approaches
    are either computationally expensive, require very specialized capture hardware,
    or are extremely labor intensive. At runtime, given an arbitrary facial expression,
    the algorithm computes the skin strain from the relative distance between marker
    points and derives fine-scale corrections for the largescale deformation. During
    gameplay only the sparse set of marker-point positions is transmitted to the GPU.
    The face animation is entirely computed on the GPU where the resulting mesh can
    directly be used as input for the rendering stages. This data can be easily obtained
    by traditional capture hardware. The proposed in-game algorithm is fast. It also
    is easy to implement and maps well onto programmable GPUs.
author:
- first_name: Bernd
  full_name: Bernd Bickel
  id: 49876194-F248-11E8-B48F-1D18A9856A87
  last_name: Bickel
  orcid: 0000-0001-6511-9385
- first_name: Manuel
  full_name: Lang, Manuel
  last_name: Lang
citation:
  ama: 'Bickel B, Lang M. From sparse mocap to highly detailed facial animation. In:
    <i>GPU Computing Gems Emerald Edition</i>. Science Direct; 2011:413-426. doi:<a
    href="https://doi.org/10.1016/B978-0-12-384988-5.00027-9">10.1016/B978-0-12-384988-5.00027-9</a>'
  apa: Bickel, B., &#38; Lang, M. (2011). From sparse mocap to highly detailed facial
    animation. In <i>GPU Computing Gems Emerald Edition</i> (pp. 413–426). Science
    Direct. <a href="https://doi.org/10.1016/B978-0-12-384988-5.00027-9">https://doi.org/10.1016/B978-0-12-384988-5.00027-9</a>
  chicago: Bickel, Bernd, and Manuel Lang. “From Sparse Mocap to Highly Detailed Facial
    Animation.” In <i>GPU Computing Gems Emerald Edition</i>, 413–26. Science Direct,
    2011. <a href="https://doi.org/10.1016/B978-0-12-384988-5.00027-9">https://doi.org/10.1016/B978-0-12-384988-5.00027-9</a>.
  ieee: B. Bickel and M. Lang, “From sparse mocap to highly detailed facial animation,”
    in <i>GPU Computing Gems Emerald Edition</i>, Science Direct, 2011, pp. 413–426.
  ista: 'Bickel B, Lang M. 2011.From sparse mocap to highly detailed facial animation.
    In: GPU Computing Gems Emerald Edition. , 413–426.'
  mla: Bickel, Bernd, and Manuel Lang. “From Sparse Mocap to Highly Detailed Facial
    Animation.” <i>GPU Computing Gems Emerald Edition</i>, Science Direct, 2011, pp.
    413–26, doi:<a href="https://doi.org/10.1016/B978-0-12-384988-5.00027-9">10.1016/B978-0-12-384988-5.00027-9</a>.
  short: B. Bickel, M. Lang, in:, GPU Computing Gems Emerald Edition, Science Direct,
    2011, pp. 413–426.
date_created: 2018-12-11T11:55:42Z
date_published: 2011-01-01T00:00:00Z
date_updated: 2021-01-12T06:55:17Z
day: '01'
doi: 10.1016/B978-0-12-384988-5.00027-9
extern: 1
month: '01'
page: 413 - 426
publication: GPU Computing Gems Emerald Edition
publication_status: published
publisher: Science Direct
publist_id: '4935'
quality_controlled: 0
status: public
title: From sparse mocap to highly detailed facial animation
type: book_chapter
year: '2011'
...
---
_id: '2099'
abstract:
- lang: eng
  text: We present a new technique for passive and markerless facial performance capture
    based on anchor frames. Our method starts with high resolution per-frame geometry
    acquisition using state-of-theart stereo reconstruction, and proceeds to establish
    a single triangle mesh that is propagated through the entire performance. Leveraging
    the fact that facial performances often contain repetitive subsequences, we identify
    anchor frames as those which contain similar facial expressions to a manually
    chosen reference expression. Anchor frames are automatically computed over one
    or even multiple performances. We introduce a robust image-space tracking method
    that computes pixel matches directly from the reference frame to all anchor frames,
    and thereby to the remaining frames in the sequence via sequential matching. This
    allows us to propagate one reconstructed frame to an entire sequence in parallel,
    in contrast to previous sequential methods. Our anchored reconstruction approach
    also limits tracker drift and robustly handles occlusions and motion blur. The
    parallel tracking and mesh propagation offer low computation times. Our technique
    will even automatically match anchor frames across different sequences captured
    on different occasions, propagating a single mesh to all performances.
author:
- first_name: Thabo
  full_name: Beeler, Thabo
  last_name: Beeler
- first_name: Fabian
  full_name: Hahn, Fabian
  last_name: Hahn
- first_name: Derek
  full_name: Bradley, Derek J
  last_name: Bradley
- first_name: Bernd
  full_name: Bernd Bickel
  id: 49876194-F248-11E8-B48F-1D18A9856A87
  last_name: Bickel
  orcid: 0000-0001-6511-9385
- first_name: Paul
  full_name: Beardsley, Paul A
  last_name: Beardsley
- first_name: Craig
  full_name: Gotsman, Craig
  last_name: Gotsman
- first_name: Robert
  full_name: Sumner, Robert W
  last_name: Sumner
- first_name: Markus
  full_name: Groß, Markus S
  last_name: Groß
citation:
  ama: Beeler T, Hahn F, Bradley D, et al. High-quality passive facial performance
    capture using anchor frames. <i>ACM Transactions on Graphics</i>. 2011;30(4).
    doi:<a href="https://doi.org/10.1145/2010324.1964970">10.1145/2010324.1964970</a>
  apa: Beeler, T., Hahn, F., Bradley, D., Bickel, B., Beardsley, P., Gotsman, C.,
    … Groß, M. (2011). High-quality passive facial performance capture using anchor
    frames. <i>ACM Transactions on Graphics</i>. ACM. <a href="https://doi.org/10.1145/2010324.1964970">https://doi.org/10.1145/2010324.1964970</a>
  chicago: Beeler, Thabo, Fabian Hahn, Derek Bradley, Bernd Bickel, Paul Beardsley,
    Craig Gotsman, Robert Sumner, and Markus Groß. “High-Quality Passive Facial Performance
    Capture Using Anchor Frames.” <i>ACM Transactions on Graphics</i>. ACM, 2011.
    <a href="https://doi.org/10.1145/2010324.1964970">https://doi.org/10.1145/2010324.1964970</a>.
  ieee: T. Beeler <i>et al.</i>, “High-quality passive facial performance capture
    using anchor frames,” <i>ACM Transactions on Graphics</i>, vol. 30, no. 4. ACM,
    2011.
  ista: Beeler T, Hahn F, Bradley D, Bickel B, Beardsley P, Gotsman C, Sumner R, Groß
    M. 2011. High-quality passive facial performance capture using anchor frames.
    ACM Transactions on Graphics. 30(4).
  mla: Beeler, Thabo, et al. “High-Quality Passive Facial Performance Capture Using
    Anchor Frames.” <i>ACM Transactions on Graphics</i>, vol. 30, no. 4, ACM, 2011,
    doi:<a href="https://doi.org/10.1145/2010324.1964970">10.1145/2010324.1964970</a>.
  short: T. Beeler, F. Hahn, D. Bradley, B. Bickel, P. Beardsley, C. Gotsman, R. Sumner,
    M. Groß, ACM Transactions on Graphics 30 (2011).
date_created: 2018-12-11T11:55:42Z
date_published: 2011-07-01T00:00:00Z
date_updated: 2021-01-12T06:55:17Z
day: '01'
doi: 10.1145/2010324.1964970
extern: 1
intvolume: '        30'
issue: '4'
month: '07'
publication: ACM Transactions on Graphics
publication_status: published
publisher: ACM
publist_id: '4936'
quality_controlled: 0
status: public
title: High-quality passive facial performance capture using anchor frames
type: journal_article
volume: 30
year: '2011'
...
---
_id: '2100'
abstract:
- lang: eng
  text: Acquiring panoramic images using stitching takes a lot of time and moving
    objects may cause ghosting. It is also difficult to obtain a full spherical panorama,
    because the downward picture cannot be captured while the camera is mounted on
    the tripod.
author:
- first_name: Jonas
  full_name: Pfeil, Jonas
  last_name: Pfeil
- first_name: Kristian
  full_name: Hildebrand, Kristian
  last_name: Hildebrand
- first_name: Carsten
  full_name: Gremzow, Carsten
  last_name: Gremzow
- first_name: Bernd
  full_name: Bernd Bickel
  id: 49876194-F248-11E8-B48F-1D18A9856A87
  last_name: Bickel
  orcid: 0000-0001-6511-9385
- first_name: Marc
  full_name: Alexa, Marc
  last_name: Alexa
citation:
  ama: 'Pfeil J, Hildebrand K, Gremzow C, Bickel B, Alexa M. Throwable panoramic ball
    camera. In: ACM; 2011. doi:<a href="https://doi.org/10.1145/2073370.2073373">10.1145/2073370.2073373</a>'
  apa: Pfeil, J., Hildebrand, K., Gremzow, C., Bickel, B., &#38; Alexa, M. (2011).
    Throwable panoramic ball camera. Presented at the SIGGRAPH Asia, ACM. <a href="https://doi.org/10.1145/2073370.2073373">https://doi.org/10.1145/2073370.2073373</a>
  chicago: Pfeil, Jonas, Kristian Hildebrand, Carsten Gremzow, Bernd Bickel, and Marc
    Alexa. “Throwable Panoramic Ball Camera.” ACM, 2011. <a href="https://doi.org/10.1145/2073370.2073373">https://doi.org/10.1145/2073370.2073373</a>.
  ieee: J. Pfeil, K. Hildebrand, C. Gremzow, B. Bickel, and M. Alexa, “Throwable panoramic
    ball camera,” presented at the SIGGRAPH Asia, 2011.
  ista: Pfeil J, Hildebrand K, Gremzow C, Bickel B, Alexa M. 2011. Throwable panoramic
    ball camera. SIGGRAPH Asia.
  mla: Pfeil, Jonas, et al. <i>Throwable Panoramic Ball Camera</i>. ACM, 2011, doi:<a
    href="https://doi.org/10.1145/2073370.2073373">10.1145/2073370.2073373</a>.
  short: J. Pfeil, K. Hildebrand, C. Gremzow, B. Bickel, M. Alexa, in:, ACM, 2011.
conference:
  name: SIGGRAPH Asia
date_created: 2018-12-11T11:55:43Z
date_published: 2011-12-01T00:00:00Z
date_updated: 2021-01-12T06:55:19Z
day: '01'
doi: 10.1145/2073370.2073373
extern: 1
month: '12'
publication_status: published
publisher: ACM
publist_id: '4934'
quality_controlled: 0
status: public
title: Throwable panoramic ball camera
type: conference
year: '2011'
...
---
OA_type: closed access
_id: '21107'
abstract:
- lang: eng
  text: The crystal structure of the decamer sequence d(CGGGTACCCG)4 as a four-way
    Holliday junction has been determined at 2.35 Å resolution. The sequence was designed
    in order to understand the principles that govern the relationship between sequence
    and branching structure. It crystallized as a four-way junction structure with
    an overall geometry similar to those of previously determined Holliday junction
    structures.
article_processing_charge: No
article_type: original
author:
- first_name: Pradeep K
  full_name: Mandal, Pradeep K
  id: 6a3def15-d4b4-11ef-9fa9-a24c1f545ec3
  last_name: Mandal
  orcid: 0000-0001-5996-956X
- first_name: S.
  full_name: Venkadesh, S.
  last_name: Venkadesh
- first_name: N.
  full_name: Gautham, N.
  last_name: Gautham
citation:
  ama: Mandal PK, Venkadesh S, Gautham N. Structure of d(CGGGTACCCG)4 as a four-way
    Holliday junction. <i>Acta Crystallographica Section F Structural Biology Communications</i>.
    2011;67(12):1506-1510. doi:<a href="https://doi.org/10.1107/s1744309111046616">10.1107/s1744309111046616</a>
  apa: Mandal, P. K., Venkadesh, S., &#38; Gautham, N. (2011). Structure of d(CGGGTACCCG)4
    as a four-way Holliday junction. <i>Acta Crystallographica Section F Structural
    Biology Communications</i>. International Union of Crystallography. <a href="https://doi.org/10.1107/s1744309111046616">https://doi.org/10.1107/s1744309111046616</a>
  chicago: Mandal, Pradeep K, S. Venkadesh, and N. Gautham. “Structure of d(CGGGTACCCG)4
    as a Four-Way Holliday Junction.” <i>Acta Crystallographica Section F Structural
    Biology Communications</i>. International Union of Crystallography, 2011. <a href="https://doi.org/10.1107/s1744309111046616">https://doi.org/10.1107/s1744309111046616</a>.
  ieee: P. K. Mandal, S. Venkadesh, and N. Gautham, “Structure of d(CGGGTACCCG)4 as
    a four-way Holliday junction,” <i>Acta Crystallographica Section F Structural
    Biology Communications</i>, vol. 67, no. 12. International Union of Crystallography,
    pp. 1506–1510, 2011.
  ista: Mandal PK, Venkadesh S, Gautham N. 2011. Structure of d(CGGGTACCCG)4 as a
    four-way Holliday junction. Acta Crystallographica Section F Structural Biology
    Communications. 67(12), 1506–1510.
  mla: Mandal, Pradeep K., et al. “Structure of d(CGGGTACCCG)4 as a Four-Way Holliday
    Junction.” <i>Acta Crystallographica Section F Structural Biology Communications</i>,
    vol. 67, no. 12, International Union of Crystallography, 2011, pp. 1506–10, doi:<a
    href="https://doi.org/10.1107/s1744309111046616">10.1107/s1744309111046616</a>.
  short: P.K. Mandal, S. Venkadesh, N. Gautham, Acta Crystallographica Section F Structural
    Biology Communications 67 (2011) 1506–1510.
date_created: 2026-01-29T22:06:25Z
date_published: 2011-12-01T00:00:00Z
date_updated: 2026-02-23T08:59:44Z
day: '01'
doi: 10.1107/s1744309111046616
extern: '1'
has_accepted_license: '1'
intvolume: '        67'
issue: '12'
language:
- iso: eng
month: '12'
oa_version: None
page: 1506-1510
publication: Acta Crystallographica Section F Structural Biology Communications
publication_identifier:
  issn:
  - 1744-3091
publication_status: published
publisher: International Union of Crystallography
quality_controlled: '1'
status: public
title: Structure of d(CGGGTACCCG)4 as a four-way Holliday junction
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 67
year: '2011'
...
---
OA_type: free access
_id: '21108'
abstract:
- lang: eng
  text: We report here the crystal structure of the partially self-complementary decameric
    sequence d(CGGCGGCCGC), which self assembles to form a four-way junction with
    sticky ends. Each junction binds to four others through Watson–Crick base pairing
    at the sticky ends to form a rhombic structure. The rhombuses bind to each other
    and form two dimensional tiles. The tiles stack to form the crystal. The crystal
    diffracted in the space group P1 to a resolution of 2.5 Å. The junction has the
    anti-parallel stacked-X conformation like other junction structures, though the
    formation of the rhombic net noticeably alters the details of the junction geometry.
article_processing_charge: No
article_type: original
author:
- first_name: S.
  full_name: Venkadesh, S.
  last_name: Venkadesh
- first_name: Pradeep K
  full_name: Mandal, Pradeep K
  id: 6a3def15-d4b4-11ef-9fa9-a24c1f545ec3
  last_name: Mandal
  orcid: 0000-0001-5996-956X
- first_name: N.
  full_name: Gautham, N.
  last_name: Gautham
citation:
  ama: Venkadesh S, Mandal PK, Gautham N. The sequence d(CGGCGGCCGC) self-assembles
    into a two dimensional rhombic DNA lattice. <i>Biochemical and Biophysical Research
    Communications</i>. 2011;407(3):548-551. doi:<a href="https://doi.org/10.1016/j.bbrc.2011.03.056">10.1016/j.bbrc.2011.03.056</a>
  apa: Venkadesh, S., Mandal, P. K., &#38; Gautham, N. (2011). The sequence d(CGGCGGCCGC)
    self-assembles into a two dimensional rhombic DNA lattice. <i>Biochemical and
    Biophysical Research Communications</i>. Elsevier. <a href="https://doi.org/10.1016/j.bbrc.2011.03.056">https://doi.org/10.1016/j.bbrc.2011.03.056</a>
  chicago: Venkadesh, S., Pradeep K Mandal, and N. Gautham. “The Sequence d(CGGCGGCCGC)
    Self-Assembles into a Two Dimensional Rhombic DNA Lattice.” <i>Biochemical and
    Biophysical Research Communications</i>. Elsevier, 2011. <a href="https://doi.org/10.1016/j.bbrc.2011.03.056">https://doi.org/10.1016/j.bbrc.2011.03.056</a>.
  ieee: S. Venkadesh, P. K. Mandal, and N. Gautham, “The sequence d(CGGCGGCCGC) self-assembles
    into a two dimensional rhombic DNA lattice,” <i>Biochemical and Biophysical Research
    Communications</i>, vol. 407, no. 3. Elsevier, pp. 548–551, 2011.
  ista: Venkadesh S, Mandal PK, Gautham N. 2011. The sequence d(CGGCGGCCGC) self-assembles
    into a two dimensional rhombic DNA lattice. Biochemical and Biophysical Research
    Communications. 407(3), 548–551.
  mla: Venkadesh, S., et al. “The Sequence d(CGGCGGCCGC) Self-Assembles into a Two
    Dimensional Rhombic DNA Lattice.” <i>Biochemical and Biophysical Research Communications</i>,
    vol. 407, no. 3, Elsevier, 2011, pp. 548–51, doi:<a href="https://doi.org/10.1016/j.bbrc.2011.03.056">10.1016/j.bbrc.2011.03.056</a>.
  short: S. Venkadesh, P.K. Mandal, N. Gautham, Biochemical and Biophysical Research
    Communications 407 (2011) 548–551.
date_created: 2026-01-29T22:09:20Z
date_published: 2011-04-15T00:00:00Z
date_updated: 2026-02-20T09:11:23Z
day: '15'
doi: 10.1016/j.bbrc.2011.03.056
extern: '1'
external_id:
  pmid:
  - '21419105'
has_accepted_license: '1'
intvolume: '       407'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.bbrc.2011.03.056
month: '04'
oa: 1
oa_version: Published Version
page: 548-551
pmid: 1
publication: Biochemical and Biophysical Research Communications
publication_identifier:
  issn:
  - 0006-291X
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: The sequence d(CGGCGGCCGC) self-assembles into a two dimensional rhombic DNA
  lattice
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 407
year: '2011'
...
---
OA_type: free access
_id: '21109'
abstract:
- lang: eng
  text: We report the 2.6 Å resolution crystal structure of the tetra-decamer d(CGCGGGTACCCGCG)
    in the tetragonal space group P43. This sequence contains the KpnI restriction
    site GGTACC in the centre which is flanked by alternating ‘CG’ sequences, and
    has a ‘TA’ step at the centre. These are features could favour the left-handed
    Z type helix. Despite this, overall the molecule has the A form. This is the first
    tetra-decamer crystallized in the A-DNA conformation, i.e. more than one full
    turn of the A helix. The crystallographic asymmetric unit consists of one tetra-decamer
    duplex. The helical twist and slide, as well as the base pair–base pair stacking
    interactions show alternations at the alternating pyrimidine–purine and purine–pyrimidine
    base steps. This variation is reminiscent of the dinucleotide repeat in left-handed
    Z-DNA helices. The crystal packing is unlike other A-DNA crystal structures, with
    each helix having a large number of contacts of many different types with symmetry-related
    neighbours.
article_processing_charge: No
article_type: original
author:
- first_name: S.
  full_name: Venkadesh, S.
  last_name: Venkadesh
- first_name: Pradeep K
  full_name: Mandal, Pradeep K
  id: 6a3def15-d4b4-11ef-9fa9-a24c1f545ec3
  last_name: Mandal
  orcid: 0000-0001-5996-956X
- first_name: N.
  full_name: Gautham, N.
  last_name: Gautham
citation:
  ama: Venkadesh S, Mandal PK, Gautham N. The structure of a full turn of an A-DNA
    duplex d(CGCGGGTACCCGCG)2. <i>Biochemical and Biophysical Research Communications</i>.
    2011;407(2):307-312. doi:<a href="https://doi.org/10.1016/j.bbrc.2011.03.007">10.1016/j.bbrc.2011.03.007</a>
  apa: Venkadesh, S., Mandal, P. K., &#38; Gautham, N. (2011). The structure of a
    full turn of an A-DNA duplex d(CGCGGGTACCCGCG)2. <i>Biochemical and Biophysical
    Research Communications</i>. Elsevier. <a href="https://doi.org/10.1016/j.bbrc.2011.03.007">https://doi.org/10.1016/j.bbrc.2011.03.007</a>
  chicago: Venkadesh, S., Pradeep K Mandal, and N. Gautham. “The Structure of a Full
    Turn of an A-DNA Duplex d(CGCGGGTACCCGCG)2.” <i>Biochemical and Biophysical Research
    Communications</i>. Elsevier, 2011. <a href="https://doi.org/10.1016/j.bbrc.2011.03.007">https://doi.org/10.1016/j.bbrc.2011.03.007</a>.
  ieee: S. Venkadesh, P. K. Mandal, and N. Gautham, “The structure of a full turn
    of an A-DNA duplex d(CGCGGGTACCCGCG)2,” <i>Biochemical and Biophysical Research
    Communications</i>, vol. 407, no. 2. Elsevier, pp. 307–312, 2011.
  ista: Venkadesh S, Mandal PK, Gautham N. 2011. The structure of a full turn of an
    A-DNA duplex d(CGCGGGTACCCGCG)2. Biochemical and Biophysical Research Communications.
    407(2), 307–312.
  mla: Venkadesh, S., et al. “The Structure of a Full Turn of an A-DNA Duplex d(CGCGGGTACCCGCG)2.”
    <i>Biochemical and Biophysical Research Communications</i>, vol. 407, no. 2, Elsevier,
    2011, pp. 307–12, doi:<a href="https://doi.org/10.1016/j.bbrc.2011.03.007">10.1016/j.bbrc.2011.03.007</a>.
  short: S. Venkadesh, P.K. Mandal, N. Gautham, Biochemical and Biophysical Research
    Communications 407 (2011) 307–312.
date_created: 2026-01-29T22:10:30Z
date_published: 2011-04-08T00:00:00Z
date_updated: 2026-02-20T09:01:51Z
day: '08'
doi: 10.1016/j.bbrc.2011.03.007
extern: '1'
external_id:
  pmid:
  - '21397589'
has_accepted_license: '1'
intvolume: '       407'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.bbrc.2011.03.007
month: '04'
oa: 1
oa_version: None
page: 307-312
pmid: 1
publication: Biochemical and Biophysical Research Communications
publication_identifier:
  issn:
  - 0006-291X
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: The structure of a full turn of an A-DNA duplex d(CGCGGGTACCCGCG)2
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 407
year: '2011'
...
---
_id: '2116'
abstract:
- lang: eng
  text: Let P be the Ornstein-Uhlenbeck semigroup associated with the stochastic Cauchy
    problem  dU(t)=AU(t)dt+dWH(t), where A is the generator of a C 0-semigroup S on
    a Banach space E, H is a Hilbert subspace of E, and W H is an H-cylindrical Brownian
    motion. Assuming that S restricts to a C 0-semigroup on H, we obtain L p -bounds
    for D H P(t). We show that if P is analytic, then the invariance assumption is
    fulfilled. As an application we determine the L p -domain of the generator of
    P explicitly in the case where S restricts to a C 0-semigroup on H which is similar
    to an analytic contraction semigroup. The results are applied to the 1D stochastic
    heat equation driven by additive space-time white noise.
acknowledgement: 'The authors are supported by VIDI subsidy 639.032.201 (JM) and VICI
  subsidy 639.033.604 (JvN) of the Netherlands Organisation for Scientific Research
  (NWO). '
author:
- first_name: Jan
  full_name: Jan Maas
  id: 4C5696CE-F248-11E8-B48F-1D18A9856A87
  last_name: Maas
  orcid: 0000-0002-0845-1338
- first_name: Jan
  full_name: Van Neerven, Jan
  last_name: Van Neerven
citation:
  ama: 'Maas J, Van Neerven J. Gradient estimates and domain identification for analytic
    Ornstein-Uhlenbeck operators. In: <i>Parabolic Problems</i>. Vol 80. Birkhäuser;
    2011:463-477. doi:<a href="https://doi.org/10.1007/978-3-0348-0075-4_24">10.1007/978-3-0348-0075-4_24</a>'
  apa: Maas, J., &#38; Van Neerven, J. (2011). Gradient estimates and domain identification
    for analytic Ornstein-Uhlenbeck operators. In <i>Parabolic Problems</i> (Vol.
    80, pp. 463–477). Birkhäuser. <a href="https://doi.org/10.1007/978-3-0348-0075-4_24">https://doi.org/10.1007/978-3-0348-0075-4_24</a>
  chicago: Maas, Jan, and Jan Van Neerven. “Gradient Estimates and Domain Identification
    for Analytic Ornstein-Uhlenbeck Operators.” In <i>Parabolic Problems</i>, 80:463–77.
    Birkhäuser, 2011. <a href="https://doi.org/10.1007/978-3-0348-0075-4_24">https://doi.org/10.1007/978-3-0348-0075-4_24</a>.
  ieee: J. Maas and J. Van Neerven, “Gradient estimates and domain identification
    for analytic Ornstein-Uhlenbeck operators,” in <i>Parabolic Problems</i>, vol.
    80, Birkhäuser, 2011, pp. 463–477.
  ista: 'Maas J, Van Neerven J. 2011.Gradient estimates and domain identification
    for analytic Ornstein-Uhlenbeck operators. In: Parabolic Problems. vol. 80, 463–477.'
  mla: Maas, Jan, and Jan Van Neerven. “Gradient Estimates and Domain Identification
    for Analytic Ornstein-Uhlenbeck Operators.” <i>Parabolic Problems</i>, vol. 80,
    Birkhäuser, 2011, pp. 463–77, doi:<a href="https://doi.org/10.1007/978-3-0348-0075-4_24">10.1007/978-3-0348-0075-4_24</a>.
  short: J. Maas, J. Van Neerven, in:, Parabolic Problems, Birkhäuser, 2011, pp. 463–477.
date_created: 2018-12-11T11:55:48Z
date_published: 2011-06-10T00:00:00Z
date_updated: 2021-01-12T06:55:24Z
day: '10'
doi: 10.1007/978-3-0348-0075-4_24
extern: 1
intvolume: '        80'
main_file_link:
- open_access: '1'
  url: 'http://arxiv.org/abs/0911.4336 '
month: '06'
oa: 1
page: 463 - 477
publication: Parabolic Problems
publication_status: published
publisher: Birkhäuser
publist_id: '4918'
quality_controlled: 0
status: public
title: Gradient estimates and domain identification for analytic Ornstein-Uhlenbeck
  operators
type: book_chapter
volume: 80
year: '2011'
...
---
_id: '2122'
abstract:
- lang: eng
  text: We study, in L1(R̃n; γ) with respect to the gaussian measure, non- tangential
    maximal functions and conical square functions associ- ated with the Ornstein-Uhlenbeck
    operator by developing a set of techniques which allow us, to some extent, to
    compensate for the non-doubling character of the gaussian measure. The main result
    asserts that conical square functions can be controlled in L1-norm by non-tangential
    maximal functions. Along the way we prove a change of aperture result for the
    latter. This complements recent results on gaussian Hardy spaces due to Mauceri
    and Meda.
acknowledgement: The first named author is supported by Rubicon subsidy 680-50-0901
  of the Netherlands Organisation for Scientific Research (NWO). The second named
  author is supported by VICI subsidy 639.033.604 of the Netherlands Organisation
  for Scientific Research (NWO
author:
- first_name: Jan
  full_name: Jan Maas
  id: 4C5696CE-F248-11E8-B48F-1D18A9856A87
  last_name: Maas
  orcid: 0000-0002-0845-1338
- first_name: Jan
  full_name: van Neerven, Jan M
  last_name: Van Neerven
- first_name: Pierre
  full_name: Portal, Pierre
  last_name: Portal
citation:
  ama: Maas J, Van Neerven J, Portal P. Conical square functions and non-tangential
    maximal functions with respect to the Gaussian measure. <i>Publicacions Matemàtiques</i>.
    2011;55(2):313-341. doi:<a href="https://doi.org/10.5565/PUBLMAT_55211_03  ">10.5565/PUBLMAT_55211_03 
    </a>
  apa: Maas, J., Van Neerven, J., &#38; Portal, P. (2011). Conical square functions
    and non-tangential maximal functions with respect to the Gaussian measure. <i>Publicacions
    Matemàtiques</i>. Universitat Autònoma de Barcelona, Departament de Matemàtique.
    <a href="https://doi.org/10.5565/PUBLMAT_55211_03  ">https://doi.org/10.5565/PUBLMAT_55211_03 
    </a>
  chicago: Maas, Jan, Jan Van Neerven, and Pierre Portal. “Conical Square Functions
    and Non-Tangential Maximal Functions with Respect to the Gaussian Measure.” <i>Publicacions
    Matemàtiques</i>. Universitat Autònoma de Barcelona, Departament de Matemàtique,
    2011. <a href="https://doi.org/10.5565/PUBLMAT_55211_03  ">https://doi.org/10.5565/PUBLMAT_55211_03 
    </a>.
  ieee: J. Maas, J. Van Neerven, and P. Portal, “Conical square functions and non-tangential
    maximal functions with respect to the Gaussian measure,” <i>Publicacions Matemàtiques</i>,
    vol. 55, no. 2. Universitat Autònoma de Barcelona, Departament de Matemàtique,
    pp. 313–341, 2011.
  ista: Maas J, Van Neerven J, Portal P. 2011. Conical square functions and non-tangential
    maximal functions with respect to the Gaussian measure. Publicacions Matemàtiques.
    55(2), 313–341.
  mla: Maas, Jan, et al. “Conical Square Functions and Non-Tangential Maximal Functions
    with Respect to the Gaussian Measure.” <i>Publicacions Matemàtiques</i>, vol.
    55, no. 2, Universitat Autònoma de Barcelona, Departament de Matemàtique, 2011,
    pp. 313–41, doi:<a href="https://doi.org/10.5565/PUBLMAT_55211_03  ">10.5565/PUBLMAT_55211_03 
    </a>.
  short: J. Maas, J. Van Neerven, P. Portal, Publicacions Matemàtiques 55 (2011) 313–341.
date_created: 2018-12-11T11:55:50Z
date_published: 2011-07-01T00:00:00Z
date_updated: 2021-01-12T06:55:26Z
day: '01'
doi: "10.5565/PUBLMAT_55211_03\t "
extern: 1
intvolume: '        55'
issue: '2'
main_file_link:
- open_access: '1'
  url: http://arxiv.org/abs/1003.4092
month: '07'
oa: 1
page: 313 - 341
publication: Publicacions Matemàtiques
publication_status: published
publisher: Universitat Autònoma de Barcelona, Departament de Matemàtique
publist_id: '4910'
quality_controlled: 0
status: public
title: Conical square functions and non-tangential maximal functions with respect
  to the Gaussian measure
type: journal_article
volume: 55
year: '2011'
...
---
_id: '2123'
abstract:
- lang: eng
  text: We prove a Trotter product formula for gradient flows in metric spaces. This
    result is applied to establish convergence in the L 2-Wasserstein metric of the
    splitting method for some Fokker-Planck equations and porous medium type equations
    perturbed by a potential.
acknowledgement: The second named author is supported by Rubicon subsidy 680-50-0901
  of the Netherlands Organisation for Scientific Research (NWO).
article_processing_charge: No
author:
- first_name: Philippe
  full_name: Clément, Philippe
  last_name: Clément
- first_name: Jan
  full_name: Maas, Jan
  id: 4C5696CE-F248-11E8-B48F-1D18A9856A87
  last_name: Maas
  orcid: 0000-0002-0845-1338
citation:
  ama: Clément P, Maas J. A Trotter product formula for gradient flows in metric spaces.
    <i>Journal of Evolution Equations</i>. 2011;11(2):405-427. doi:<a href="https://doi.org/10.1007/s00028-010-0096-5">10.1007/s00028-010-0096-5</a>
  apa: Clément, P., &#38; Maas, J. (2011). A Trotter product formula for gradient
    flows in metric spaces. <i>Journal of Evolution Equations</i>. Birkhäuser. <a
    href="https://doi.org/10.1007/s00028-010-0096-5">https://doi.org/10.1007/s00028-010-0096-5</a>
  chicago: Clément, Philippe, and Jan Maas. “A Trotter Product Formula for Gradient
    Flows in Metric Spaces.” <i>Journal of Evolution Equations</i>. Birkhäuser, 2011.
    <a href="https://doi.org/10.1007/s00028-010-0096-5">https://doi.org/10.1007/s00028-010-0096-5</a>.
  ieee: P. Clément and J. Maas, “A Trotter product formula for gradient flows in metric
    spaces,” <i>Journal of Evolution Equations</i>, vol. 11, no. 2. Birkhäuser, pp.
    405–427, 2011.
  ista: Clément P, Maas J. 2011. A Trotter product formula for gradient flows in metric
    spaces. Journal of Evolution Equations. 11(2), 405–427.
  mla: Clément, Philippe, and Jan Maas. “A Trotter Product Formula for Gradient Flows
    in Metric Spaces.” <i>Journal of Evolution Equations</i>, vol. 11, no. 2, Birkhäuser,
    2011, pp. 405–27, doi:<a href="https://doi.org/10.1007/s00028-010-0096-5">10.1007/s00028-010-0096-5</a>.
  short: P. Clément, J. Maas, Journal of Evolution Equations 11 (2011) 405–427.
date_created: 2018-12-11T11:55:51Z
date_published: 2011-01-21T00:00:00Z
date_updated: 2021-11-16T08:05:46Z
day: '21'
doi: 10.1007/s00028-010-0096-5
extern: '1'
intvolume: '        11'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://arxiv.org/abs/1005.0998
month: '01'
oa: 1
oa_version: None
page: 405 - 427
publication: Journal of Evolution Equations
publication_status: published
publisher: Birkhäuser
publist_id: '4911'
related_material:
  link:
  - relation: erratum
    url: https://doi.org/10.1007/s00028-012-0173-z
status: public
title: A Trotter product formula for gradient flows in metric spaces
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 11
year: '2011'
...
---
_id: '2126'
abstract:
- lang: eng
  text: |
    Let K be an irreducible and reversible Markov kernel on a finite set X. We construct a metric W on the set of probability measures on X and show that with respect to this metric, the law of the continuous time Markov chain evolves as the gradient flow of the entropy. This result is a discrete counterpart of the Wasserstein gradient flow interpretation of the heat flow in Rn by Jordan, Kinderlehrer and Otto (1998). The metric W is similar to, but different from, the L2-Wasserstein metric, and is defined via a discrete variant of the Benamou–Brenier formula.
acknowledgement: Supported by Rubicon subsidy 680-50-0901 of the Netherlands Organisation
  for Scientific Research (NWO)
author:
- first_name: Jan
  full_name: Jan Maas
  id: 4C5696CE-F248-11E8-B48F-1D18A9856A87
  last_name: Maas
  orcid: 0000-0002-0845-1338
citation:
  ama: Maas J. Gradient flows of the entropy for finite Markov chains. <i>Journal
    of Functional Analysis</i>. 2011;261(8):2250-2292. doi:<a href="https://doi.org/10.1016/j.jfa.2011.06.009
    ">10.1016/j.jfa.2011.06.009 </a>
  apa: Maas, J. (2011). Gradient flows of the entropy for finite Markov chains. <i>Journal
    of Functional Analysis</i>. Academic Press. <a href="https://doi.org/10.1016/j.jfa.2011.06.009
    ">https://doi.org/10.1016/j.jfa.2011.06.009 </a>
  chicago: Maas, Jan. “Gradient Flows of the Entropy for Finite Markov Chains.” <i>Journal
    of Functional Analysis</i>. Academic Press, 2011. <a href="https://doi.org/10.1016/j.jfa.2011.06.009
    ">https://doi.org/10.1016/j.jfa.2011.06.009 </a>.
  ieee: J. Maas, “Gradient flows of the entropy for finite Markov chains,” <i>Journal
    of Functional Analysis</i>, vol. 261, no. 8. Academic Press, pp. 2250–2292, 2011.
  ista: Maas J. 2011. Gradient flows of the entropy for finite Markov chains. Journal
    of Functional Analysis. 261(8), 2250–2292.
  mla: Maas, Jan. “Gradient Flows of the Entropy for Finite Markov Chains.” <i>Journal
    of Functional Analysis</i>, vol. 261, no. 8, Academic Press, 2011, pp. 2250–92,
    doi:<a href="https://doi.org/10.1016/j.jfa.2011.06.009 ">10.1016/j.jfa.2011.06.009
    </a>.
  short: J. Maas, Journal of Functional Analysis 261 (2011) 2250–2292.
date_created: 2018-12-11T11:55:51Z
date_published: 2011-03-04T00:00:00Z
date_updated: 2021-01-12T06:55:28Z
day: '04'
doi: '10.1016/j.jfa.2011.06.009 '
extern: 1
intvolume: '       261'
issue: '8'
main_file_link:
- open_access: '1'
  url: http://arxiv.org/abs/1102.5238
month: '03'
oa: 1
page: 2250 - 2292
publication: Journal of Functional Analysis
publication_status: published
publisher: Academic Press
publist_id: '4909'
quality_controlled: 0
status: public
title: Gradient flows of the entropy for finite Markov chains
type: journal_article
volume: 261
year: '2011'
...
---
_id: '2138'
abstract:
- lang: eng
  text: A (diatomic) shape resonance is a metastable state of a pair of colliding
    atoms quasi-bound by the centrifugal barrier imposed by the angular momentum involved
    in the collision. The temporary trapping of the atoms' scattering wavefunction
    corresponds to an enhanced atom pair density at low interatomic separations. This
    leads to larger overlap of the wavefunctions involved in a molecule formation
    process such as photoassociation, rendering the process more efficient. However,
    for an ensemble of atoms, the atom pair density will only be enhanced if the energy
    of the resonance comes close to the temperature of the atomic ensemble. Herein
    we explore the possibility of controlling the energy of a shape resonance by shifting
    it toward the temperature of atoms confined in a trap. The shifts are imparted
    by the interaction of non-resonant light with the anisotropic polarizability of
    the atom pair, which affects both the centrifugal barrier and the pair's rotational
    and vibrational levels. We find that at laser intensities of up to 5×109 W/cm2
    the pair density is increased by one order of magnitude for 87Rb atoms at 100μK
    and by two orders of magnitude for 88Sr atoms at 20μK.
acknowledgement: Financial support from the Deutsche Forschungsgemeinschaft (Grant
  No. KO 2301/2), by the Spanish project FIS2008-02380 (MICINN) as well as the Grants
  FQM-2445 and FQM-4643 (Junta de Andaluc´ıa), Campus de Excelencia Internacional
  Proyecto GENIL CEB09-0010
author:
- first_name: Ruzin
  full_name: Ağanoğlu, Ruzin
  last_name: Ağanoğlu
- first_name: Mikhail
  full_name: Mikhail Lemeshko
  id: 37CB05FA-F248-11E8-B48F-1D18A9856A87
  last_name: Lemeshko
  orcid: 0000-0002-6990-7802
- first_name: Břetislav
  full_name: Friedrich, Břetislav
  last_name: Friedrich
- first_name: Rosario
  full_name: González-Férez, Rosario
  last_name: González Férez
- first_name: Christiane
  full_name: Koch, Christiane P
  last_name: Koch
citation:
  ama: Ağanoğlu R, Lemeshko M, Friedrich B, González Férez R, Koch C. Controlling
    a diatomic shape resonance with non-resonant light. <i>Unknown</i>. 2011.
  apa: Ağanoğlu, R., Lemeshko, M., Friedrich, B., González Férez, R., &#38; Koch,
    C. (2011). Controlling a diatomic shape resonance with non-resonant light. <i>Unknown</i>.
    ArXiv.
  chicago: Ağanoğlu, Ruzin, Mikhail Lemeshko, Břetislav Friedrich, Rosario González
    Férez, and Christiane Koch. “Controlling a Diatomic Shape Resonance with Non-Resonant
    Light.” <i>Unknown</i>. ArXiv, 2011.
  ieee: R. Ağanoğlu, M. Lemeshko, B. Friedrich, R. González Férez, and C. Koch, “Controlling
    a diatomic shape resonance with non-resonant light,” <i>Unknown</i>. ArXiv, 2011.
  ista: Ağanoğlu R, Lemeshko M, Friedrich B, González Férez R, Koch C. 2011. Controlling
    a diatomic shape resonance with non-resonant light. Unknown, .
  mla: Ağanoğlu, Ruzin, et al. “Controlling a Diatomic Shape Resonance with Non-Resonant
    Light.” <i>Unknown</i>, ArXiv, 2011.
  short: R. Ağanoğlu, M. Lemeshko, B. Friedrich, R. González Férez, C. Koch, Unknown
    (2011).
date_created: 2018-12-11T11:55:55Z
date_published: 2011-05-04T00:00:00Z
date_updated: 2021-01-12T06:55:32Z
day: '04'
extern: 1
main_file_link:
- open_access: '1'
  url: http://arxiv.org/abs/1105.0761
month: '05'
oa: 1
publication: Unknown
publication_status: published
publisher: ArXiv
publist_id: '4886'
quality_controlled: 0
status: public
title: Controlling a diatomic shape resonance with non-resonant light
type: preprint
year: '2011'
...
---
_id: '2198'
abstract:
- lang: eng
  text: We show that dressing polar molecules with a far-off-resonant optical field
    leads to new types of intermolecular potentials, which undergo a crossover from
    the inverse power to oscillating behavior depending on the intermolecular distance,
    and whose parameters can be tuned by varying the laser intensity and wavelength.
    We present analytic expressions for the potential energy surfaces, thereby providing
    direct access to the parameters of an optical field required to design intermolecular
    interactions experimentally.
author:
- first_name: Mikhail
  full_name: Mikhail Lemeshko
  id: 37CB05FA-F248-11E8-B48F-1D18A9856A87
  last_name: Lemeshko
  orcid: 0000-0002-6990-7802
citation:
  ama: Lemeshko M. Shaping interactions between polar molecules with far-off-resonant
    light. <i>Physical Review A - Atomic, Molecular, and Optical Physics</i>. 2011;83(5).
    doi:<a href="https://doi.org/10.1103/PhysRevA.83.051402">10.1103/PhysRevA.83.051402</a>
  apa: Lemeshko, M. (2011). Shaping interactions between polar molecules with far-off-resonant
    light. <i>Physical Review A - Atomic, Molecular, and Optical Physics</i>. American
    Physical Society. <a href="https://doi.org/10.1103/PhysRevA.83.051402">https://doi.org/10.1103/PhysRevA.83.051402</a>
  chicago: Lemeshko, Mikhail. “Shaping Interactions between Polar Molecules with Far-off-Resonant
    Light.” <i>Physical Review A - Atomic, Molecular, and Optical Physics</i>. American
    Physical Society, 2011. <a href="https://doi.org/10.1103/PhysRevA.83.051402">https://doi.org/10.1103/PhysRevA.83.051402</a>.
  ieee: M. Lemeshko, “Shaping interactions between polar molecules with far-off-resonant
    light,” <i>Physical Review A - Atomic, Molecular, and Optical Physics</i>, vol.
    83, no. 5. American Physical Society, 2011.
  ista: Lemeshko M. 2011. Shaping interactions between polar molecules with far-off-resonant
    light. Physical Review A - Atomic, Molecular, and Optical Physics. 83(5).
  mla: Lemeshko, Mikhail. “Shaping Interactions between Polar Molecules with Far-off-Resonant
    Light.” <i>Physical Review A - Atomic, Molecular, and Optical Physics</i>, vol.
    83, no. 5, American Physical Society, 2011, doi:<a href="https://doi.org/10.1103/PhysRevA.83.051402">10.1103/PhysRevA.83.051402</a>.
  short: M. Lemeshko, Physical Review A - Atomic, Molecular, and Optical Physics 83
    (2011).
date_created: 2018-12-11T11:56:17Z
date_published: 2011-05-27T00:00:00Z
date_updated: 2021-01-12T06:55:55Z
day: '27'
doi: 10.1103/PhysRevA.83.051402
extern: 1
intvolume: '        83'
issue: '5'
main_file_link:
- open_access: '1'
  url: http://arxiv.org/abs/1104.1046
month: '05'
oa: 1
publication: Physical Review A - Atomic, Molecular, and Optical Physics
publication_status: published
publisher: American Physical Society
publist_id: '4775'
quality_controlled: 0
status: public
title: Shaping interactions between polar molecules with far-off-resonant light
type: journal_article
volume: 83
year: '2011'
...
---
_id: '14305'
abstract:
- lang: eng
  text: Understanding the mechanism of protein folding requires a detailed knowledge
    of the structural properties of the barriers separating unfolded from native conformations.
    The S-peptide from ribonuclease S forms its α-helical structure only upon binding
    to the folded S-protein. We characterized the transition state for this binding-induced
    folding reaction at high resolution by determining the effect of site-specific
    backbone thioxylation and side-chain modifications on the kinetics and thermodynamics
    of the reaction, which allows us to monitor formation of backbone hydrogen bonds
    and side-chain interactions in the transition state. The experiments reveal that
    α-helical structure in the S-peptide is absent in the transition state of binding.
    Recognition between the unfolded S-peptide and the S-protein is mediated by loosely
    packed hydrophobic side-chain interactions in two well defined regions on the
    S-peptide. Close packing and helix formation occurs rapidly after binding. Introducing
    hydrophobic residues at positions outside the recognition region can drastically
    slow down association.
article_processing_charge: No
article_type: original
author:
- first_name: Annett
  full_name: Bachmann, Annett
  last_name: Bachmann
- first_name: Dirk
  full_name: Wildemann, Dirk
  last_name: Wildemann
- first_name: Florian M
  full_name: Praetorius, Florian M
  id: dfec9381-4341-11ee-8fd8-faa02bba7d62
  last_name: Praetorius
- first_name: Gunter
  full_name: Fischer, Gunter
  last_name: Fischer
- first_name: Thomas
  full_name: Kiefhaber, Thomas
  last_name: Kiefhaber
citation:
  ama: Bachmann A, Wildemann D, Praetorius FM, Fischer G, Kiefhaber T. Mapping backbone
    and side-chain interactions in the transition state of a coupled protein folding
    and binding reaction. <i>PNAS</i>. 2011;108(10):3952-3957. doi:<a href="https://doi.org/10.1073/pnas.1012668108">10.1073/pnas.1012668108</a>
  apa: Bachmann, A., Wildemann, D., Praetorius, F. M., Fischer, G., &#38; Kiefhaber,
    T. (2011). Mapping backbone and side-chain interactions in the transition state
    of a coupled protein folding and binding reaction. <i>PNAS</i>. Proceedings of
    the National Academy of Sciences. <a href="https://doi.org/10.1073/pnas.1012668108">https://doi.org/10.1073/pnas.1012668108</a>
  chicago: Bachmann, Annett, Dirk Wildemann, Florian M Praetorius, Gunter Fischer,
    and Thomas Kiefhaber. “Mapping Backbone and Side-Chain Interactions in the Transition
    State of a Coupled Protein Folding and Binding Reaction.” <i>PNAS</i>. Proceedings
    of the National Academy of Sciences, 2011. <a href="https://doi.org/10.1073/pnas.1012668108">https://doi.org/10.1073/pnas.1012668108</a>.
  ieee: A. Bachmann, D. Wildemann, F. M. Praetorius, G. Fischer, and T. Kiefhaber,
    “Mapping backbone and side-chain interactions in the transition state of a coupled
    protein folding and binding reaction,” <i>PNAS</i>, vol. 108, no. 10. Proceedings
    of the National Academy of Sciences, pp. 3952–3957, 2011.
  ista: Bachmann A, Wildemann D, Praetorius FM, Fischer G, Kiefhaber T. 2011. Mapping
    backbone and side-chain interactions in the transition state of a coupled protein
    folding and binding reaction. PNAS. 108(10), 3952–3957.
  mla: Bachmann, Annett, et al. “Mapping Backbone and Side-Chain Interactions in the
    Transition State of a Coupled Protein Folding and Binding Reaction.” <i>PNAS</i>,
    vol. 108, no. 10, Proceedings of the National Academy of Sciences, 2011, pp. 3952–57,
    doi:<a href="https://doi.org/10.1073/pnas.1012668108">10.1073/pnas.1012668108</a>.
  short: A. Bachmann, D. Wildemann, F.M. Praetorius, G. Fischer, T. Kiefhaber, PNAS
    108 (2011) 3952–3957.
date_created: 2023-09-06T12:54:36Z
date_published: 2011-01-12T00:00:00Z
date_updated: 2023-11-07T11:50:29Z
day: '12'
doi: 10.1073/pnas.1012668108
extern: '1'
external_id:
  pmid:
  - '21325613'
intvolume: '       108'
issue: '10'
keyword:
- Multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1073/pnas.1012668108
month: '01'
oa: 1
oa_version: Published Version
page: 3952-3957
pmid: 1
publication: PNAS
publication_identifier:
  eissn:
  - 1091-6490
  issn:
  - 0027-8424
publication_status: published
publisher: Proceedings of the National Academy of Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mapping backbone and side-chain interactions in the transition state of a coupled
  protein folding and binding reaction
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 108
year: '2011'
...
---
_id: '1467'
abstract:
- lang: eng
  text: We propose a general conjecture for the mixed Hodge polynomial of the generic
    character varieties of representations of the fundamental group of a Riemann surface
    of genus g to GLn(C) with fixed generic semisimple conjugacy classes at k punctures.
    This conjecture generalizes the Cauchy identity for Macdonald polynomials and
    is a common generalization of two formulas that we prove in this paper. The first
    is a formula for the E-polynomial of these character varieties which we obtain
    using the character table of GLn(Fq). We use this formula to compute the Euler
    characteristic of character varieties. The second formula gives the Poincaré polynomial
    of certain associated quiver varieties which we obtain using the character table
    of gln(Fq). In the last main result we prove that the Poincaré polynomials of
    the quiver varieties equal certain multiplicities in the tensor product of irreducible
    characters of GLn(Fq). As a consequence we find a curious connection between Kac-Moody
    algebras associated with comet-shaped, and typically wild, quivers and the representation
    theory of GLn(Fq).
acknowledgement: |-
  Hausel’s work was supported by National Science Foundation grants DMS-0305505 and DMS-0604775, by an Alfred Sloan Fellowship, and by a Royal Society University Research Fellowship. Letellier’s work supported by Agence Nationale de la Recherche grant ANR-09-JCJC-0102-01.
  Rodriguez-Villegas’s work supported by National Science Foundation grant DMS-0200605, by an FRA from the University of Texas at Austin, by EPSRC grant EP/G027110/1, by visiting fellowships at All Souls and Wadham Colleges in Oxford, and by a Research Scholarship from the Clay Mathematical Institute.
author:
- first_name: Tamas
  full_name: Tamas Hausel
  id: 4A0666D8-F248-11E8-B48F-1D18A9856A87
  last_name: Hausel
- first_name: Emmanuel
  full_name: Letellier, Emmanuel
  last_name: Letellier
- first_name: Fernando
  full_name: Rodríguez Villegas, Fernando
  last_name: Rodríguez Villegas
citation:
  ama: Hausel T, Letellier E, Rodríguez Villegas F. Arithmetic harmonic analysis on
    character and quiver varieties. <i>Duke Mathematical Journal</i>. 2011;160(2):323-400.
    doi:<a href="https://doi.org/10.1215/00127094-1444258">10.1215/00127094-1444258</a>
  apa: Hausel, T., Letellier, E., &#38; Rodríguez Villegas, F. (2011). Arithmetic
    harmonic analysis on character and quiver varieties. <i>Duke Mathematical Journal</i>.
    Duke University Press. <a href="https://doi.org/10.1215/00127094-1444258">https://doi.org/10.1215/00127094-1444258</a>
  chicago: Hausel, Tamás, Emmanuel Letellier, and Fernando Rodríguez Villegas. “Arithmetic
    Harmonic Analysis on Character and Quiver Varieties.” <i>Duke Mathematical Journal</i>.
    Duke University Press, 2011. <a href="https://doi.org/10.1215/00127094-1444258">https://doi.org/10.1215/00127094-1444258</a>.
  ieee: T. Hausel, E. Letellier, and F. Rodríguez Villegas, “Arithmetic harmonic analysis
    on character and quiver varieties,” <i>Duke Mathematical Journal</i>, vol. 160,
    no. 2. Duke University Press, pp. 323–400, 2011.
  ista: Hausel T, Letellier E, Rodríguez Villegas F. 2011. Arithmetic harmonic analysis
    on character and quiver varieties. Duke Mathematical Journal. 160(2), 323–400.
  mla: Hausel, Tamás, et al. “Arithmetic Harmonic Analysis on Character and Quiver
    Varieties.” <i>Duke Mathematical Journal</i>, vol. 160, no. 2, Duke University
    Press, 2011, pp. 323–400, doi:<a href="https://doi.org/10.1215/00127094-1444258">10.1215/00127094-1444258</a>.
  short: T. Hausel, E. Letellier, F. Rodríguez Villegas, Duke Mathematical Journal
    160 (2011) 323–400.
date_created: 2018-12-11T11:52:11Z
date_published: 2011-01-01T00:00:00Z
date_updated: 2021-01-12T06:50:56Z
day: '01'
doi: 10.1215/00127094-1444258
extern: 1
intvolume: '       160'
issue: '2'
main_file_link:
- open_access: '1'
  url: http://arxiv.org/abs/0810.2076
month: '01'
oa: 1
page: 323 - 400
publication: Duke Mathematical Journal
publication_status: published
publisher: Duke University Press
publist_id: '5728'
quality_controlled: 0
status: public
title: Arithmetic harmonic analysis on character and quiver varieties
type: journal_article
volume: 160
year: '2011'
...
---
_id: '1863'
abstract:
- lang: eng
  text: The Levene model is the simplest mathematical model to describe the evolution
    of gene frequencies in spatially subdivided populations. It provides insight into
    how locally varying selection promotes a population’s genetic diversity. Despite
    its simplicity, interesting problems have remained unsolved even in the diallelic
    case. In this paper we answer an open problem by establishing that for two alleles
    at one locus and J demes, up to 2J−1 polymorphic equilibria may coexist. We first
    present a proof for the case of stable monomorphisms and then show that the result
    also holds for protected alleles. These findings allow us to prove that any odd
    number (up to 2J−1) of equilibria is possible, before we extend the proof to even
    numbers. We conclude with some numerical results and show that for J&gt;2, the
    proportion of parameter space affording this maximum is extremely small.
acknowledgement: FWF 21305
author:
- first_name: Sebastian
  full_name: Sebastian Novak
  id: 461468AE-F248-11E8-B48F-1D18A9856A87
  last_name: Novak
citation:
  ama: Novak S. The number of equilibria in the diallelic Levene model with multiple
    demes. <i>Theoretical Population Biology</i>. 2011;79(3):97-101. doi:<a href="https://doi.org/10.1016/j.tpb.2010.12.002">10.1016/j.tpb.2010.12.002</a>
  apa: Novak, S. (2011). The number of equilibria in the diallelic Levene model with
    multiple demes. <i>Theoretical Population Biology</i>. Academic Press. <a href="https://doi.org/10.1016/j.tpb.2010.12.002">https://doi.org/10.1016/j.tpb.2010.12.002</a>
  chicago: Novak, Sebastian. “The Number of Equilibria in the Diallelic Levene Model
    with Multiple Demes.” <i>Theoretical Population Biology</i>. Academic Press, 2011.
    <a href="https://doi.org/10.1016/j.tpb.2010.12.002">https://doi.org/10.1016/j.tpb.2010.12.002</a>.
  ieee: S. Novak, “The number of equilibria in the diallelic Levene model with multiple
    demes,” <i>Theoretical Population Biology</i>, vol. 79, no. 3. Academic Press,
    pp. 97–101, 2011.
  ista: Novak S. 2011. The number of equilibria in the diallelic Levene model with
    multiple demes. Theoretical Population Biology. 79(3), 97–101.
  mla: Novak, Sebastian. “The Number of Equilibria in the Diallelic Levene Model with
    Multiple Demes.” <i>Theoretical Population Biology</i>, vol. 79, no. 3, Academic
    Press, 2011, pp. 97–101, doi:<a href="https://doi.org/10.1016/j.tpb.2010.12.002">10.1016/j.tpb.2010.12.002</a>.
  short: S. Novak, Theoretical Population Biology 79 (2011) 97–101.
date_created: 2018-12-11T11:54:25Z
date_published: 2011-05-01T00:00:00Z
date_updated: 2021-01-12T06:53:42Z
day: '01'
doi: 10.1016/j.tpb.2010.12.002
extern: 1
intvolume: '        79'
issue: '3'
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '05'
page: 97 - 101
publication: Theoretical Population Biology
publication_status: published
publisher: Academic Press
publist_id: '5236'
quality_controlled: 0
status: public
title: The number of equilibria in the diallelic Levene model with multiple demes
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
volume: 79
year: '2011'
...
---
_id: '1973'
abstract:
- lang: eng
  text: Complex I is the first and largest enzyme of the respiratory chain, coupling
    electron transfer between NADH and ubiquinone to the translocation of four protons
    across the membrane. It has a central role in cellular energy production and has
    been implicated in many human neurodegenerative diseases. The L-shaped enzyme
    consists of hydrophilic and membrane domains. Previously, we determined the structure
    of the hydrophilic domain. Here we report the crystal structure of the Esherichia
    coli complex I membrane domain at 3.0 Ã. resolution. It includes six subunits,
    NuoL, NuoM, NuoN, NuoA, NuoJ and NuoK, with 55 transmembrane helices. The fold
    of the homologous antiporter-like subunits L, M and N is novel, with two inverted
    structural repeats of five transmembrane helices arranged, unusually, face-to-back.
    Each repeat includes a discontinuous transmembrane helix and forms half of a channel
    across the membrane. A network of conserved polar residues connects the two half-channels,
    completing the proton translocation pathway. Unexpectedly, lysines rather than
    carboxylate residues act as the main elements of the proton pump in these subunits.
    The fourth probable proton-translocation channel is at the interface of subunits
    N, K, J and A. The structure indicates that proton translocation in complex I,
    uniquely, involves coordinated conformational changes in six symmetrical structural
    elements.
acknowledgement: This work was funded by the Medical Research Council.
author:
- first_name: Rouslan
  full_name: Efremov, Rouslan G
  last_name: Efremov
- first_name: Leonid A
  full_name: Leonid Sazanov
  id: 338D39FE-F248-11E8-B48F-1D18A9856A87
  last_name: Sazanov
  orcid: 0000-0002-0977-7989
citation:
  ama: Efremov R, Sazanov LA. Structure of the membrane domain of respiratory complex
    i. <i>Nature</i>. 2011;476(7361):414-421. doi:<a href="https://doi.org/10.1038/nature10330">10.1038/nature10330</a>
  apa: Efremov, R., &#38; Sazanov, L. A. (2011). Structure of the membrane domain
    of respiratory complex i. <i>Nature</i>. Nature Publishing Group. <a href="https://doi.org/10.1038/nature10330">https://doi.org/10.1038/nature10330</a>
  chicago: Efremov, Rouslan, and Leonid A Sazanov. “Structure of the Membrane Domain
    of Respiratory Complex I.” <i>Nature</i>. Nature Publishing Group, 2011. <a href="https://doi.org/10.1038/nature10330">https://doi.org/10.1038/nature10330</a>.
  ieee: R. Efremov and L. A. Sazanov, “Structure of the membrane domain of respiratory
    complex i,” <i>Nature</i>, vol. 476, no. 7361. Nature Publishing Group, pp. 414–421,
    2011.
  ista: Efremov R, Sazanov LA. 2011. Structure of the membrane domain of respiratory
    complex i. Nature. 476(7361), 414–421.
  mla: Efremov, Rouslan, and Leonid A. Sazanov. “Structure of the Membrane Domain
    of Respiratory Complex I.” <i>Nature</i>, vol. 476, no. 7361, Nature Publishing
    Group, 2011, pp. 414–21, doi:<a href="https://doi.org/10.1038/nature10330">10.1038/nature10330</a>.
  short: R. Efremov, L.A. Sazanov, Nature 476 (2011) 414–421.
date_created: 2018-12-11T11:54:59Z
date_published: 2011-08-25T00:00:00Z
date_updated: 2021-01-12T06:54:26Z
day: '25'
doi: 10.1038/nature10330
extern: 1
intvolume: '       476'
issue: '7361'
month: '08'
page: 414 - 421
publication: Nature
publication_status: published
publisher: Nature Publishing Group
publist_id: '5110'
quality_controlled: 0
status: public
title: Structure of the membrane domain of respiratory complex i
type: journal_article
volume: 476
year: '2011'
...
---
_id: '1974'
abstract:
- lang: eng
  text: Complex I is the first enzyme of the respiratory chain and plays a central
    role in cellular energy production. It has been implicated in many human neurodegenerative
    diseases, as well as in ageing. One of the biggest membrane protein complexes,
    it is an L-shaped assembly consisting of hydrophilic and membrane domains. Previously,
    we have determined structures of the hydrophilic domain in several redox states.
    Last year was marked by fascinating breakthroughs in the understanding of the
    complete structure. We described the architecture of the membrane domain and of
    the entire bacterial complex I. X-ray analysis of the larger mitochondrial enzyme
    has also been published. The core subunits of the bacterial and mitochondrial
    enzymes have remarkably similar structures. The proposed mechanism of coupling
    between electron transfer and proton translocation involves long-range conformational
    changes, coordinated in part by a long α-helix, akin to the coupling rod of a
    steam engine.
acknowledgement: The work in authors’ laboratory was funded by the Medical Research
  Council.
author:
- first_name: Rouslan
  full_name: Efremov, Rouslan G
  last_name: Efremov
- first_name: Leonid A
  full_name: Leonid Sazanov
  id: 338D39FE-F248-11E8-B48F-1D18A9856A87
  last_name: Sazanov
  orcid: 0000-0002-0977-7989
citation:
  ama: 'Efremov R, Sazanov LA. Respiratory complex I: “steam engine” of the cell?
    <i>Current Opinion in Structural Biology</i>. 2011;21(4):532-540. doi:<a href="https://doi.org/10.1016/j.sbi.2011.07.002">10.1016/j.sbi.2011.07.002</a>'
  apa: 'Efremov, R., &#38; Sazanov, L. A. (2011). Respiratory complex I: “steam engine”
    of the cell? <i>Current Opinion in Structural Biology</i>. Elsevier. <a href="https://doi.org/10.1016/j.sbi.2011.07.002">https://doi.org/10.1016/j.sbi.2011.07.002</a>'
  chicago: 'Efremov, Rouslan, and Leonid A Sazanov. “Respiratory Complex I: ‘steam
    Engine’ of the Cell?” <i>Current Opinion in Structural Biology</i>. Elsevier,
    2011. <a href="https://doi.org/10.1016/j.sbi.2011.07.002">https://doi.org/10.1016/j.sbi.2011.07.002</a>.'
  ieee: 'R. Efremov and L. A. Sazanov, “Respiratory complex I: ‘steam engine’ of the
    cell?,” <i>Current Opinion in Structural Biology</i>, vol. 21, no. 4. Elsevier,
    pp. 532–540, 2011.'
  ista: 'Efremov R, Sazanov LA. 2011. Respiratory complex I: ‘steam engine’ of the
    cell? Current Opinion in Structural Biology. 21(4), 532–540.'
  mla: 'Efremov, Rouslan, and Leonid A. Sazanov. “Respiratory Complex I: ‘steam Engine’
    of the Cell?” <i>Current Opinion in Structural Biology</i>, vol. 21, no. 4, Elsevier,
    2011, pp. 532–40, doi:<a href="https://doi.org/10.1016/j.sbi.2011.07.002">10.1016/j.sbi.2011.07.002</a>.'
  short: R. Efremov, L.A. Sazanov, Current Opinion in Structural Biology 21 (2011)
    532–540.
date_created: 2018-12-11T11:54:59Z
date_published: 2011-08-01T00:00:00Z
date_updated: 2021-01-12T06:54:27Z
day: '01'
doi: 10.1016/j.sbi.2011.07.002
extern: 1
intvolume: '        21'
issue: '4'
month: '08'
page: 532 - 540
publication: Current Opinion in Structural Biology
publication_status: published
publisher: Elsevier
publist_id: '5111'
quality_controlled: 0
status: public
title: 'Respiratory complex I: ''steam engine'' of the cell?'
type: journal_article
volume: 21
year: '2011'
...
---
_id: '1975'
abstract:
- lang: eng
  text: 'Modern α-proteobacteria are thought to be closely related to the ancient
    symbiont of eukaryotes, an ancestor of mitochondria. Respiratory complex I from
    α-proteobacteria and mitochondria is well conserved at the level of the 14 &quot;core&quot;
    subunits, consistent with that notion. Mitochondrial complex I contains the core
    subunits, present in all species, and up to 31 &quot;supernumerary&quot; subunits,
    generally thought to have originated only within eukaryotic lineages. However,
    the full protein composition of an α-proteobacterial complex I has not been established
    previously. Here, we report the first purification and characterization of complex
    I from the α-proteobacterium Paracoccus denitrificans. Single particle electron
    microscopy shows that the complex has a well defined L-shape. Unexpectedly, in
    addition to the 14 core subunits, the enzyme also contains homologues of three
    supernumerary mitochondrial subunits as follows: B17.2, AQDQ/18, and 13 kDa (bovine
    nomenclature). This finding suggests that evolution of complex I via addition
    of supernumerary or &quot;accessory&quot; subunits started before the original
    endosymbiotic event that led to the creation of the eukaryotic cell. It also provides
    further confirmation that α-proteobacteria are the closest extant relatives of
    mitochondria.'
acknowledgement: 'This work was supported by the Medical Research Council. '
author:
- first_name: Chui
  full_name: Yip, Chui Y
  last_name: Yip
- first_name: Michael
  full_name: Harbour, Michael E
  last_name: Harbour
- first_name: Kamburapola
  full_name: Jayawardena, Kamburapola G
  last_name: Jayawardena
- first_name: Ian
  full_name: Fearnley, Ian M
  last_name: Fearnley
- first_name: Leonid A
  full_name: Leonid Sazanov
  id: 338D39FE-F248-11E8-B48F-1D18A9856A87
  last_name: Sazanov
  orcid: 0000-0002-0977-7989
citation:
  ama: Yip C, Harbour M, Jayawardena K, Fearnley I, Sazanov LA. Evolution of respiratory
    complex I &#38;quot;Supernumerary&#38;quot; subunits are present in the α-proteobacterial
    enzyme. <i>Journal of Biological Chemistry</i>. 2011;286(7):5023-5033. doi:<a
    href="https://doi.org/10.1074/jbc.M110.194993">10.1074/jbc.M110.194993</a>
  apa: Yip, C., Harbour, M., Jayawardena, K., Fearnley, I., &#38; Sazanov, L. A. (2011).
    Evolution of respiratory complex I &#38;quot;Supernumerary&#38;quot; subunits
    are present in the α-proteobacterial enzyme. <i>Journal of Biological Chemistry</i>.
    American Society for Biochemistry and Molecular Biology. <a href="https://doi.org/10.1074/jbc.M110.194993">https://doi.org/10.1074/jbc.M110.194993</a>
  chicago: Yip, Chui, Michael Harbour, Kamburapola Jayawardena, Ian Fearnley, and
    Leonid A Sazanov. “Evolution of Respiratory Complex I &#38;quot;Supernumerary&#38;quot;
    Subunits Are Present in the α-Proteobacterial Enzyme.” <i>Journal of Biological
    Chemistry</i>. American Society for Biochemistry and Molecular Biology, 2011.
    <a href="https://doi.org/10.1074/jbc.M110.194993">https://doi.org/10.1074/jbc.M110.194993</a>.
  ieee: C. Yip, M. Harbour, K. Jayawardena, I. Fearnley, and L. A. Sazanov, “Evolution
    of respiratory complex I &#38;quot;Supernumerary&#38;quot; subunits are present
    in the α-proteobacterial enzyme,” <i>Journal of Biological Chemistry</i>, vol.
    286, no. 7. American Society for Biochemistry and Molecular Biology, pp. 5023–5033,
    2011.
  ista: Yip C, Harbour M, Jayawardena K, Fearnley I, Sazanov LA. 2011. Evolution of
    respiratory complex I &#38;quot;Supernumerary&#38;quot; subunits are present in
    the α-proteobacterial enzyme. Journal of Biological Chemistry. 286(7), 5023–5033.
  mla: Yip, Chui, et al. “Evolution of Respiratory Complex I &#38;quot;Supernumerary&#38;quot;
    Subunits Are Present in the α-Proteobacterial Enzyme.” <i>Journal of Biological
    Chemistry</i>, vol. 286, no. 7, American Society for Biochemistry and Molecular
    Biology, 2011, pp. 5023–33, doi:<a href="https://doi.org/10.1074/jbc.M110.194993">10.1074/jbc.M110.194993</a>.
  short: C. Yip, M. Harbour, K. Jayawardena, I. Fearnley, L.A. Sazanov, Journal of
    Biological Chemistry 286 (2011) 5023–5033.
date_created: 2018-12-11T11:55:00Z
date_published: 2011-02-18T00:00:00Z
date_updated: 2021-01-12T06:54:27Z
day: '18'
doi: 10.1074/jbc.M110.194993
extern: 1
intvolume: '       286'
issue: '7'
month: '02'
page: 5023 - 5033
publication: Journal of Biological Chemistry
publication_status: published
publisher: American Society for Biochemistry and Molecular Biology
publist_id: '5112'
quality_controlled: 0
status: public
title: Evolution of respiratory complex I &quot;Supernumerary&quot; subunits are present
  in the α-proteobacterial enzyme
type: journal_article
volume: 286
year: '2011'
...
---
_id: '469'
abstract:
- lang: eng
  text: 'Spontaneous release of glutamate is important for maintaining synaptic strength
    and controlling spike timing in the brain. Mechanisms regulating spontaneous exocytosis
    remain poorly understood. Extracellular calcium concentration ([Ca2+]o) regulates
    Ca2+ entry through voltage-activated calcium channels (VACCs) and consequently
    is a pivotal determinant of action potential-evoked vesicle fusion. Extracellular
    Ca 2+ also enhances spontaneous release, but via unknown mechanisms. Here we report
    that external Ca2+ triggers spontaneous glutamate release more weakly than evoked
    release in mouse neocortical neurons. Blockade of VACCs has no effect on the spontaneous
    release rate or its dependence on [Ca2+]o. Intracellular [Ca2+] slowly increases
    in a minority of neurons following increases in [Ca2+]o. Furthermore, the enhancement
    of spontaneous release by extracellular calcium is insensitive to chelation of
    intracellular calcium by BAPTA. Activation of the calcium-sensing receptor (CaSR),
    a G-protein-coupled receptor present in nerve terminals, by several specific agonists
    increased spontaneous glutamate release. The frequency of spontaneous synaptic
    transmission was decreased in CaSR mutant neurons. The concentration-effect relationship
    for extracellular calcium regulation of spontaneous release was well described
    by a combination of CaSR-dependent and CaSR-independent mechanisms. Overall these
    results indicate that extracellular Ca2+ does not trigger spontaneous glutamate
    release by simply increasing calcium influx but stimulates CaSR and thereby promotes
    resting spontaneous glutamate release. '
article_processing_charge: No
author:
- first_name: Nicholas
  full_name: Vyleta, Nicholas
  id: 36C4978E-F248-11E8-B48F-1D18A9856A87
  last_name: Vyleta
- first_name: Stephen
  full_name: Smith, Stephen
  last_name: Smith
citation:
  ama: Vyleta N, Smith S. Spontaneous glutamate release is independent of calcium
    influx and tonically activated by the calcium-sensing receptor. <i>European Journal
    of Neuroscience</i>. 2011;31(12):4593-4606. doi:<a href="https://doi.org/10.1523/JNEUROSCI.6398-10.2011">10.1523/JNEUROSCI.6398-10.2011</a>
  apa: Vyleta, N., &#38; Smith, S. (2011). Spontaneous glutamate release is independent
    of calcium influx and tonically activated by the calcium-sensing receptor. <i>European
    Journal of Neuroscience</i>. Wiley-Blackwell. <a href="https://doi.org/10.1523/JNEUROSCI.6398-10.2011">https://doi.org/10.1523/JNEUROSCI.6398-10.2011</a>
  chicago: Vyleta, Nicholas, and Stephen Smith. “Spontaneous Glutamate Release Is
    Independent of Calcium Influx and Tonically Activated by the Calcium-Sensing Receptor.”
    <i>European Journal of Neuroscience</i>. Wiley-Blackwell, 2011. <a href="https://doi.org/10.1523/JNEUROSCI.6398-10.2011">https://doi.org/10.1523/JNEUROSCI.6398-10.2011</a>.
  ieee: N. Vyleta and S. Smith, “Spontaneous glutamate release is independent of calcium
    influx and tonically activated by the calcium-sensing receptor,” <i>European Journal
    of Neuroscience</i>, vol. 31, no. 12. Wiley-Blackwell, pp. 4593–4606, 2011.
  ista: Vyleta N, Smith S. 2011. Spontaneous glutamate release is independent of calcium
    influx and tonically activated by the calcium-sensing receptor. European Journal
    of Neuroscience. 31(12), 4593–4606.
  mla: Vyleta, Nicholas, and Stephen Smith. “Spontaneous Glutamate Release Is Independent
    of Calcium Influx and Tonically Activated by the Calcium-Sensing Receptor.” <i>European
    Journal of Neuroscience</i>, vol. 31, no. 12, Wiley-Blackwell, 2011, pp. 4593–606,
    doi:<a href="https://doi.org/10.1523/JNEUROSCI.6398-10.2011">10.1523/JNEUROSCI.6398-10.2011</a>.
  short: N. Vyleta, S. Smith, European Journal of Neuroscience 31 (2011) 4593–4606.
date_created: 2018-12-11T11:46:39Z
date_published: 2011-03-23T00:00:00Z
date_updated: 2025-09-30T09:25:10Z
day: '23'
department:
- _id: PeJo
doi: 10.1523/JNEUROSCI.6398-10.2011
external_id:
  isi:
  - '000288750700025'
intvolume: '        31'
isi: 1
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097128/
month: '03'
oa: 1
oa_version: Submitted Version
page: 4593 - 4606
publication: European Journal of Neuroscience
publication_status: published
publisher: Wiley-Blackwell
publist_id: '7353'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Spontaneous glutamate release is independent of calcium influx and tonically
  activated by the calcium-sensing receptor
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 31
year: '2011'
...
