---
OA_place: repository
OA_type: green
_id: '3379'
abstract:
- lang: eng
  text: The process of gastrulation is highly conserved across vertebrates on both
    the genetic and morphological levels, despite great variety in embryonic shape
    and speed of development. This mechanism spatially separates the germ layers and
    establishes the organizational foundation for future development. Mesodermal identity
    is specified in a superficial layer of cells, the epiblast, where cells maintain
    an epithelioid morphology. These cells involute to join the deeper hypoblast layer
    where they adopt a migratory, mesenchymal morphology. Expression of a cascade
    of related transcription factors orchestrates the parallel genetic transition
    from primitive to mature mesoderm. Although the early and late stages of this
    process are increasingly well understood, the transition between them has remained
    largely mysterious. We present here the first high resolution in vivo observations
    of the blebby transitional morphology of involuting mesodermal cells in a vertebrate
    embryo. We further demonstrate that the zebrafish spadetail mutation creates a
    reversible block in the maturation program, stalling cells in the transition state.
    This mutation creates an ideal system for dissecting the specific properties of
    cells undergoing the morphological transition of maturing mesoderm, as we demonstrate
    with a direct measurement of cell–cell adhesion.
acknowledgement: We thank David Grunwald for providing the spadetail-myc fusion construct.
  This work was supported by an NIH grant (GM079203) to D.K. and grants from the Austrian
  Academy of Sciences to P.S., and from the DFG, MPG and IST Austria to C.-P.H. R.R.
  was supported by a Developmental Biology Predoctoral Training Grant, T32HD007183,
  from the National Institute of Child Health and Human Development. B.L.M. was supported
  by an American Cancer Society fellowship (PF-07-048-01-DDC).
article_processing_charge: No
article_type: original
author:
- first_name: Richard
  full_name: Row, Richard
  last_name: Row
- first_name: Jean-Léon
  full_name: Maître, Jean-Léon
  id: 48F1E0D8-F248-11E8-B48F-1D18A9856A87
  last_name: Maître
  orcid: 0000-0002-3688-1474
- first_name: Benjamin
  full_name: Martin, Benjamin
  last_name: Martin
- first_name: Petra
  full_name: Stockinger, Petra
  id: 261CB030-E90D-11E9-B182-F697D44B663C
  last_name: Stockinger
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
- first_name: David
  full_name: Kimelman, David
  last_name: Kimelman
citation:
  ama: Row R, Maître J-L, Martin B, Stockinger P, Heisenberg C-PJ, Kimelman D. Completion
    of the epithelial to mesenchymal transition in zebrafish mesoderm requires Spadetail.
    <i>Developmental Biology</i>. 2011;354(1):102-110. doi:<a href="https://doi.org/10.1016/j.ydbio.2011.03.025">10.1016/j.ydbio.2011.03.025</a>
  apa: Row, R., Maître, J.-L., Martin, B., Stockinger, P., Heisenberg, C.-P. J., &#38;
    Kimelman, D. (2011). Completion of the epithelial to mesenchymal transition in
    zebrafish mesoderm requires Spadetail. <i>Developmental Biology</i>. Elsevier.
    <a href="https://doi.org/10.1016/j.ydbio.2011.03.025">https://doi.org/10.1016/j.ydbio.2011.03.025</a>
  chicago: Row, Richard, Jean-Léon Maître, Benjamin Martin, Petra Stockinger, Carl-Philipp
    J Heisenberg, and David Kimelman. “Completion of the Epithelial to Mesenchymal
    Transition in Zebrafish Mesoderm Requires Spadetail.” <i>Developmental Biology</i>.
    Elsevier, 2011. <a href="https://doi.org/10.1016/j.ydbio.2011.03.025">https://doi.org/10.1016/j.ydbio.2011.03.025</a>.
  ieee: R. Row, J.-L. Maître, B. Martin, P. Stockinger, C.-P. J. Heisenberg, and D.
    Kimelman, “Completion of the epithelial to mesenchymal transition in zebrafish
    mesoderm requires Spadetail,” <i>Developmental Biology</i>, vol. 354, no. 1. Elsevier,
    pp. 102–110, 2011.
  ista: Row R, Maître J-L, Martin B, Stockinger P, Heisenberg C-PJ, Kimelman D. 2011.
    Completion of the epithelial to mesenchymal transition in zebrafish mesoderm requires
    Spadetail. Developmental Biology. 354(1), 102–110.
  mla: Row, Richard, et al. “Completion of the Epithelial to Mesenchymal Transition
    in Zebrafish Mesoderm Requires Spadetail.” <i>Developmental Biology</i>, vol.
    354, no. 1, Elsevier, 2011, pp. 102–10, doi:<a href="https://doi.org/10.1016/j.ydbio.2011.03.025">10.1016/j.ydbio.2011.03.025</a>.
  short: R. Row, J.-L. Maître, B. Martin, P. Stockinger, C.-P.J. Heisenberg, D. Kimelman,
    Developmental Biology 354 (2011) 102–110.
das_tickbox: '1'
date_created: 2018-12-11T12:03:00Z
date_published: 2011-06-01T00:00:00Z
date_updated: 2026-07-28T08:31:27Z
day: '01'
department:
- _id: CaHe
doi: 10.1016/j.ydbio.2011.03.025
external_id:
  isi:
  - '000290550500010'
  pmid:
  - '21463614'
fulldoi: https://doi.org/10.1016/j.ydbio.2011.03.025
intvolume: '       354'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090540/
month: '06'
oa: 1
oa_version: Submitted Version
page: 102 - 110
pmid: 1
publication: Developmental Biology
publication_status: published
publisher: Elsevier
publist_id: '3228'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Completion of the epithelial to mesenchymal transition in zebrafish mesoderm
  requires Spadetail
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 354
year: '2011'
...
---
OA_type: closed access
_id: '3781'
abstract:
- lang: eng
  text: We bound the difference in length of two curves in terms of their total curvatures
    and the Fréchet distance. The bound is independent of the dimension of the ambient
    Euclidean space, it improves upon a bound by Cohen-Steiner and Edelsbrunner, and
    it generalizes a result by Fáry and Chakerian.
acknowledgement: Funded by Graduate Aid in Areas of National Need (GAANN) Fellowship.
  The author would like to thank Herbert Edelsbrunner for his discussions and guidance.
article_processing_charge: No
article_type: original
author:
- first_name: Brittany Terese
  full_name: Fasy, Brittany Terese
  id: F65D502E-E68D-11E9-9252-C644099818F6
  last_name: Fasy
citation:
  ama: Fasy BT. The difference in length of curves in R^n. <i>Acta Scientiarum Mathematicarum</i>.
    2011;77(1-2):359-367. doi:<a href="https://doi.org/10.1007/BF03651375">10.1007/BF03651375</a>
  apa: Fasy, B. T. (2011). The difference in length of curves in R^n. <i>Acta Scientiarum
    Mathematicarum</i>. Springer Nature. <a href="https://doi.org/10.1007/BF03651375">https://doi.org/10.1007/BF03651375</a>
  chicago: Fasy, Brittany Terese. “The Difference in Length of Curves in R^n.” <i>Acta
    Scientiarum Mathematicarum</i>. Springer Nature, 2011. <a href="https://doi.org/10.1007/BF03651375">https://doi.org/10.1007/BF03651375</a>.
  ieee: B. T. Fasy, “The difference in length of curves in R^n,” <i>Acta Scientiarum
    Mathematicarum</i>, vol. 77, no. 1–2. Springer Nature, pp. 359–367, 2011.
  ista: Fasy BT. 2011. The difference in length of curves in R^n. Acta Scientiarum
    Mathematicarum. 77(1–2), 359–367.
  mla: Fasy, Brittany Terese. “The Difference in Length of Curves in R^n.” <i>Acta
    Scientiarum Mathematicarum</i>, vol. 77, no. 1–2, Springer Nature, 2011, pp. 359–67,
    doi:<a href="https://doi.org/10.1007/BF03651375">10.1007/BF03651375</a>.
  short: B.T. Fasy, Acta Scientiarum Mathematicarum 77 (2011) 359–367.
corr_author: '1'
das_tickbox: '1'
date_created: 2018-12-11T12:05:08Z
date_published: 2011-06-01T00:00:00Z
date_updated: 2026-07-28T08:11:07Z
day: '01'
department:
- _id: HeEd
doi: 10.1007/BF03651375
fulldoi: https://doi.org/10.1007/BF03651375
intvolume: '        77'
issue: 1-2
language:
- iso: eng
month: '06'
oa_version: None
page: 359 - 367
publication: Acta Scientiarum Mathematicarum
publication_identifier:
  eissn:
  - 2064-8316
  issn:
  - 0001-6969
publication_status: published
publisher: Springer Nature
publist_id: '2446'
quality_controlled: '1'
status: public
title: The difference in length of curves in R^n
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 77
year: '2011'
...
---
OA_place: publisher
OA_type: free access
_id: '3383'
article_processing_charge: No
author:
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
citation:
  ama: 'Heisenberg C-PJ. Invited Lectures ‐ Symposia Area. In: <i>The FEBS Journal</i>.
    Vol 278. Wiley; 2011:24-24. doi:<a href="https://doi.org/10.1111/j.1742-4658.2011.08136.x">10.1111/j.1742-4658.2011.08136.x</a>'
  apa: 'Heisenberg, C.-P. J. (2011). Invited Lectures ‐ Symposia Area. In <i>The FEBS
    Journal</i> (Vol. 278, pp. 24–24). Torino, Italy: Wiley. <a href="https://doi.org/10.1111/j.1742-4658.2011.08136.x">https://doi.org/10.1111/j.1742-4658.2011.08136.x</a>'
  chicago: Heisenberg, Carl-Philipp J. “Invited Lectures ‐ Symposia Area.” In <i>The
    FEBS Journal</i>, 278:24–24. Wiley, 2011. <a href="https://doi.org/10.1111/j.1742-4658.2011.08136.x">https://doi.org/10.1111/j.1742-4658.2011.08136.x</a>.
  ieee: C.-P. J. Heisenberg, “Invited Lectures ‐ Symposia Area,” in <i>The FEBS Journal</i>,
    Torino, Italy, 2011, vol. 278, no. S1, pp. 24–24.
  ista: Heisenberg C-PJ. 2011. Invited Lectures ‐ Symposia Area. The FEBS Journal.
    FEBS Congress on Biochemistry for Tomorrow’s Medicine vol. 278, 24–24.
  mla: Heisenberg, Carl-Philipp J. “Invited Lectures ‐ Symposia Area.” <i>The FEBS
    Journal</i>, vol. 278, no. S1, Wiley, 2011, pp. 24–24, doi:<a href="https://doi.org/10.1111/j.1742-4658.2011.08136.x">10.1111/j.1742-4658.2011.08136.x</a>.
  short: C.-P.J. Heisenberg, in:, The FEBS Journal, Wiley, 2011, pp. 24–24.
conference:
  end_date: 2011-06-30
  location: Torino, Italy
  name: FEBS Congress on Biochemistry for Tomorrow's Medicine
  start_date: 2011-06-25
corr_author: '1'
date_created: 2018-12-11T12:03:01Z
date_published: 2011-07-01T00:00:00Z
date_updated: 2026-07-28T08:27:55Z
day: '01'
department:
- _id: CaHe
doi: 10.1111/j.1742-4658.2011.08136.x
fulldoi: https://doi.org/10.1111/j.1742-4658.2011.08136.x
intvolume: '       278'
issue: S1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1111/j.1742-4658.2011.08136.x
month: '07'
oa: 1
oa_version: Published Version
page: 24 - 24
publication: The FEBS Journal
publication_status: published
publisher: Wiley
publist_id: '3224'
quality_controlled: '1'
status: public
title: Invited Lectures ‐ Symposia Area
type: conference_abstract
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 278
year: '2011'
...
---
_id: '3368'
abstract:
- lang: eng
  text: Tissue surface tension (TST) is an important mechanical property influencing
    cell sorting and tissue envelopment. The study by Manning et al. (1) reported
    on a mathematical model describing TST on the basis of the balance between adhesive
    and tensile properties of the constituent cells. The model predicts that, in high-adhesion
    cell aggregates, surface cells will be stretched to maintain the same area of
    cell–cell contact as interior bulk cells, resulting in an elongated and flattened
    cell shape. The authors (1) observed flat and elongated cells at the surface of
    high-adhesion zebrafish germ-layer explants, which they argue are undifferentiated
    stretched germ-layer progenitor cells, and they use this observation as a validation
    of their model.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Gabriel
  full_name: Krens, Gabriel
  id: 2B819732-F248-11E8-B48F-1D18A9856A87
  last_name: Krens
  orcid: 0000-0003-4761-5996
- first_name: Stephanie
  full_name: Möllmert, Stephanie
  id: 260FD49C-E911-11E9-B5EA-D9538404589B
  last_name: Möllmert
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
citation:
  ama: Krens G, Möllmert S, Heisenberg C-PJ. Enveloping cell layer differentiation
    at the surface of zebrafish germ layer tissue explants. <i>PNAS</i>. 2011;108(3):E9-E10.
    doi:<a href="https://doi.org/10.1073/pnas.1010767108">10.1073/pnas.1010767108</a>
  apa: Krens, G., Möllmert, S., &#38; Heisenberg, C.-P. J. (2011). Enveloping cell
    layer differentiation at the surface of zebrafish germ layer tissue explants.
    <i>PNAS</i>. National Academy of Sciences. <a href="https://doi.org/10.1073/pnas.1010767108">https://doi.org/10.1073/pnas.1010767108</a>
  chicago: Krens, Gabriel, Stephanie Möllmert, and Carl-Philipp J Heisenberg. “Enveloping
    Cell Layer Differentiation at the Surface of Zebrafish Germ Layer Tissue Explants.”
    <i>PNAS</i>. National Academy of Sciences, 2011. <a href="https://doi.org/10.1073/pnas.1010767108">https://doi.org/10.1073/pnas.1010767108</a>.
  ieee: G. Krens, S. Möllmert, and C.-P. J. Heisenberg, “Enveloping cell layer differentiation
    at the surface of zebrafish germ layer tissue explants,” <i>PNAS</i>, vol. 108,
    no. 3. National Academy of Sciences, pp. E9–E10, 2011.
  ista: Krens G, Möllmert S, Heisenberg C-PJ. 2011. Enveloping cell layer differentiation
    at the surface of zebrafish germ layer tissue explants. PNAS. 108(3), E9–E10.
  mla: Krens, Gabriel, et al. “Enveloping Cell Layer Differentiation at the Surface
    of Zebrafish Germ Layer Tissue Explants.” <i>PNAS</i>, vol. 108, no. 3, National
    Academy of Sciences, 2011, pp. E9–10, doi:<a href="https://doi.org/10.1073/pnas.1010767108">10.1073/pnas.1010767108</a>.
  short: G. Krens, S. Möllmert, C.-P.J. Heisenberg, PNAS 108 (2011) E9–E10.
corr_author: '1'
das_tickbox: '1'
date_created: 2018-12-11T12:02:56Z
date_published: 2011-01-18T00:00:00Z
date_updated: 2026-07-28T09:03:18Z
day: '18'
department:
- _id: CaHe
doi: 10.1073/pnas.1010767108
external_id:
  isi:
  - '000286310300003'
  pmid:
  - '21212360'
fulldoi: https://doi.org/10.1073/pnas.1010767108
intvolume: '       108'
isi: 1
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024655
month: '01'
oa: 1
oa_version: Submitted Version
page: E9 - E10
pmid: 1
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '3244'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Enveloping cell layer differentiation at the surface of zebrafish germ layer
  tissue explants
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 108
year: '2011'
...
---
_id: '3373'
abstract:
- lang: eng
  text: The use of optical traps to measure or apply forces on the molecular level
    requires a precise knowledge of the trapping force field. Close to the trap center,
    this field is typically approximated as linear in the displacement of the trapped
    microsphere. However, applications demanding high forces at low laser intensities
    can probe the light-microsphere interaction beyond the linear regime. Here, we
    measured the full nonlinear force and displacement response of an optical trap
    in two dimensions using a dual-beam optical trap setup with back-focal-plane photodetection.
    We observed a substantial stiffening of the trap beyond the linear regime that
    depends on microsphere size, in agreement with Mie theory calculations. Surprisingly,
    we found that the linear detection range for forces exceeds the one for displacement
    by far. Our approach allows for a complete calibration of an optical trap.
article_processing_charge: No
author:
- first_name: Marcus
  full_name: Jahnel, Marcus
  last_name: Jahnel
- first_name: Martin
  full_name: Behrndt, Martin
  id: 3ECECA3A-F248-11E8-B48F-1D18A9856A87
  last_name: Behrndt
- first_name: Anita
  full_name: Jannasch, Anita
  last_name: Jannasch
- first_name: Erik
  full_name: Schaeffer, Erik
  last_name: Schaeffer
- first_name: Stephan
  full_name: Grill, Stephan
  last_name: Grill
citation:
  ama: Jahnel M, Behrndt M, Jannasch A, Schaeffer E, Grill S. Measuring the complete
    force field of an optical trap. <i>Optics Letters</i>. 2011;36(7):1260-1262. doi:<a
    href="https://doi.org/10.1364/OL.36.001260">10.1364/OL.36.001260</a>
  apa: Jahnel, M., Behrndt, M., Jannasch, A., Schaeffer, E., &#38; Grill, S. (2011).
    Measuring the complete force field of an optical trap. <i>Optics Letters</i>.
    Optica Publishing Group. <a href="https://doi.org/10.1364/OL.36.001260">https://doi.org/10.1364/OL.36.001260</a>
  chicago: Jahnel, Marcus, Martin Behrndt, Anita Jannasch, Erik Schaeffer, and Stephan
    Grill. “Measuring the Complete Force Field of an Optical Trap.” <i>Optics Letters</i>.
    Optica Publishing Group, 2011. <a href="https://doi.org/10.1364/OL.36.001260">https://doi.org/10.1364/OL.36.001260</a>.
  ieee: M. Jahnel, M. Behrndt, A. Jannasch, E. Schaeffer, and S. Grill, “Measuring
    the complete force field of an optical trap,” <i>Optics Letters</i>, vol. 36,
    no. 7. Optica Publishing Group, pp. 1260–1262, 2011.
  ista: Jahnel M, Behrndt M, Jannasch A, Schaeffer E, Grill S. 2011. Measuring the
    complete force field of an optical trap. Optics Letters. 36(7), 1260–1262.
  mla: Jahnel, Marcus, et al. “Measuring the Complete Force Field of an Optical Trap.”
    <i>Optics Letters</i>, vol. 36, no. 7, Optica Publishing Group, 2011, pp. 1260–62,
    doi:<a href="https://doi.org/10.1364/OL.36.001260">10.1364/OL.36.001260</a>.
  short: M. Jahnel, M. Behrndt, A. Jannasch, E. Schaeffer, S. Grill, Optics Letters
    36 (2011) 1260–1262.
date_created: 2018-12-11T12:02:58Z
date_published: 2011-03-30T00:00:00Z
date_updated: 2026-07-29T10:07:18Z
day: '30'
ddc:
- '570'
department:
- _id: CaHe
doi: 10.1364/OL.36.001260
external_id:
  isi:
  - '000289251000080'
fulldoi: https://doi.org/10.1364/OL.36.001260
intvolume: '        36'
isi: 1
issue: '7'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.osapublishing.org/ol/abstract.cfm?uri=ol-36-7-1260
month: '03'
oa: 1
oa_version: Published Version
page: 1260 - 1262
publication: Optics Letters
publication_status: published
publisher: Optica Publishing Group
publist_id: '3234'
quality_controlled: '1'
related_material:
  record:
  - id: '1403'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Measuring the complete force field of an optical trap
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 36
year: '2011'
...
---
_id: '3393'
abstract:
- lang: eng
  text: 'Unlike unconditionally advantageous “Fisherian” variants that tend to spread
    throughout a species range once introduced anywhere, “bistable” variants, such
    as chromosome translocations, have two alternative stable frequencies, absence
    and (near) fixation. Analogous to populations with Allee effects, bistable variants
    tend to increase locally only once they become sufficiently common, and their
    spread depends on their rate of increase averaged over all frequencies. Several
    proposed manipulations of insect populations, such as using Wolbachia or “engineered
    underdominance” to suppress vector-borne diseases, produce bistable rather than
    Fisherian dynamics. We synthesize and extend theoretical analyses concerning three
    features of their spatial behavior: rate of spread, conditions to initiate spread
    from a localized introduction, and wave stopping caused by variation in population
    densities or dispersal rates. Unlike Fisherian variants, bistable variants tend
    to spread spatially only for particular parameter combinations and initial conditions.
    Wave initiation requires introduction over an extended region, while subsequent
    spatial spread is slower than for Fisherian waves and can easily be halted by
    local spatial inhomogeneities. We present several new results, including robust
    sufficient conditions to initiate (and stop) spread, using a one-parameter cubic
    approximation applicable to several models. The results have both basic and applied
    implications.'
article_processing_charge: No
article_type: original
author:
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Michael
  full_name: Turelli, Michael
  last_name: Turelli
citation:
  ama: 'Barton NH, Turelli M. Spatial waves of advance with bistable dynamics: Cytoplasmic
    and genetic analogues of Allee effects. <i>American Naturalist</i>. 2011;178(3):E48-E75.
    doi:<a href="https://doi.org/10.1086/661246">10.1086/661246</a>'
  apa: 'Barton, N. H., &#38; Turelli, M. (2011). Spatial waves of advance with bistable
    dynamics: Cytoplasmic and genetic analogues of Allee effects. <i>American Naturalist</i>.
    University of Chicago Press. <a href="https://doi.org/10.1086/661246">https://doi.org/10.1086/661246</a>'
  chicago: 'Barton, Nicholas H, and Michael Turelli. “Spatial Waves of Advance with
    Bistable Dynamics: Cytoplasmic and Genetic Analogues of Allee Effects.” <i>American
    Naturalist</i>. University of Chicago Press, 2011. <a href="https://doi.org/10.1086/661246">https://doi.org/10.1086/661246</a>.'
  ieee: 'N. H. Barton and M. Turelli, “Spatial waves of advance with bistable dynamics:
    Cytoplasmic and genetic analogues of Allee effects,” <i>American Naturalist</i>,
    vol. 178, no. 3. University of Chicago Press, pp. E48–E75, 2011.'
  ista: 'Barton NH, Turelli M. 2011. Spatial waves of advance with bistable dynamics:
    Cytoplasmic and genetic analogues of Allee effects. American Naturalist. 178(3),
    E48–E75.'
  mla: 'Barton, Nicholas H., and Michael Turelli. “Spatial Waves of Advance with Bistable
    Dynamics: Cytoplasmic and Genetic Analogues of Allee Effects.” <i>American Naturalist</i>,
    vol. 178, no. 3, University of Chicago Press, 2011, pp. E48–75, doi:<a href="https://doi.org/10.1086/661246">10.1086/661246</a>.'
  short: N.H. Barton, M. Turelli, American Naturalist 178 (2011) E48–E75.
date_created: 2018-12-11T12:03:05Z
date_published: 2011-09-01T00:00:00Z
date_updated: 2026-08-04T09:17:38Z
day: '01'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1086/661246
external_id:
  isi:
  - '000294256800001'
file:
- access_level: open_access
  checksum: 7fd22a2ef3321a6fca6a439b3be5d8f4
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:08:31Z
  date_updated: 2020-07-14T12:46:11Z
  file_id: '4692'
  file_name: IST-2016-554-v1+1_BartonTurelli2011_copy.pdf
  file_size: 629130
  relation: main_file
file_date_updated: 2020-07-14T12:46:11Z
fulldoi: https://doi.org/10.1086/661246
has_accepted_license: '1'
intvolume: '       178'
isi: 1
issue: '3'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Submitted Version
page: E48 - E75
publication: American Naturalist
publication_identifier:
  eissn:
  - 1537-5323
  issn:
  - 0003-0147
publication_status: published
publisher: University of Chicago Press
publist_id: '3214'
pubrep_id: '554'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Spatial waves of advance with bistable dynamics: Cytoplasmic and genetic analogues
  of Allee effects'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 178
year: '2011'
...
---
OA_type: closed access
_id: '22556'
abstract:
- lang: eng
  text: Numerous studies across multiple disciplines search for insights on the effects
    of climate change at local spatial scales and at fine time resolutions. This study
    presents an overall methodology of using a weather generator for downscaling an
    ensemble of climate model outputs. The downscaled predictions can explicitly include
    climate model uncertainty, which offers valuable information for making probabilistic
    inferences about climate impacts. The hourly weather generator that serves as
    the downscaling tool is briefly presented. The generator is designed to reproduce
    a set of meteorological variables that can serve as input to hydrological, ecological,
    geomorphological, and agricultural models. The generator is capable of reproducing
    a wide set of climate statistics over a range of temporal scales, from extremes,
    to low-frequency interannual variability; its performance for many climate variables
    and their statistics over different aggregation periods is highly satisfactory.
    The use of the weather generator in simulations of future climate scenarios, as
    inferred from climate models, is described in detail. Using a previously developed
    methodology based on a Bayesian approach, the stochastic downscaling procedure
    derives the frequency distribution functions of factors of change for several
    climate statistics from a multi-model ensemble of outputs of General Circulation
    Models. The factors of change are subsequently applied to the statistics derived
    from observations to re-evaluate the parameters of the weather generator. Using
    embedded causal and statistical relationships, the generator simulates future
    realizations of climate for a specific point location at the hourly scale. Uncertainties
    present in the climate model realizations and the multi-model ensemble predictions
    are discussed. An application of the weather generator in reproducing present
    (1961–2000) and forecasting future (2081–2100) climate conditions is illustrated
    for the location of Tucson (AZ). The stochastic downscaling is carried out using
    simulations of eight General Circulation Models adopted in the IPCC 4AR, A1B emission
    scenario.
article_processing_charge: No
article_type: original
author:
- first_name: Simone
  full_name: Fatichi, Simone
  id: cf8e546b-a9b0-11f0-a43b-aa89ed1b56d6
  last_name: Fatichi
- first_name: Valeriy Y.
  full_name: Ivanov, Valeriy Y.
  last_name: Ivanov
- first_name: Enrica
  full_name: Caporali, Enrica
  last_name: Caporali
citation:
  ama: Fatichi S, Ivanov VY, Caporali E. Simulation of future climate scenarios with
    a weather generator. <i>Advances in Water Resources</i>. 2011;34(4):448-467. doi:<a
    href="https://doi.org/10.1016/j.advwatres.2010.12.013">10.1016/j.advwatres.2010.12.013</a>
  apa: Fatichi, S., Ivanov, V. Y., &#38; Caporali, E. (2011). Simulation of future
    climate scenarios with a weather generator. <i>Advances in Water Resources</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.advwatres.2010.12.013">https://doi.org/10.1016/j.advwatres.2010.12.013</a>
  chicago: Fatichi, Simone, Valeriy Y. Ivanov, and Enrica Caporali. “Simulation of
    Future Climate Scenarios with a Weather Generator.” <i>Advances in Water Resources</i>.
    Elsevier, 2011. <a href="https://doi.org/10.1016/j.advwatres.2010.12.013">https://doi.org/10.1016/j.advwatres.2010.12.013</a>.
  ieee: S. Fatichi, V. Y. Ivanov, and E. Caporali, “Simulation of future climate scenarios
    with a weather generator,” <i>Advances in Water Resources</i>, vol. 34, no. 4.
    Elsevier, pp. 448–467, 2011.
  ista: Fatichi S, Ivanov VY, Caporali E. 2011. Simulation of future climate scenarios
    with a weather generator. Advances in Water Resources. 34(4), 448–467.
  mla: Fatichi, Simone, et al. “Simulation of Future Climate Scenarios with a Weather
    Generator.” <i>Advances in Water Resources</i>, vol. 34, no. 4, Elsevier, 2011,
    pp. 448–67, doi:<a href="https://doi.org/10.1016/j.advwatres.2010.12.013">10.1016/j.advwatres.2010.12.013</a>.
  short: S. Fatichi, V.Y. Ivanov, E. Caporali, Advances in Water Resources 34 (2011)
    448–467.
das_tickbox: '1'
date_created: 2026-07-27T12:30:24Z
date_published: 2011-04-01T00:00:00Z
date_updated: 2026-08-06T10:13:12Z
day: '01'
doi: 10.1016/j.advwatres.2010.12.013
extern: '1'
fulldoi: https://doi.org/10.1016/j.advwatres.2010.12.013
intvolume: '        34'
issue: '4'
keyword:
- Weather generator
- Stochastic downscaling
- Climate change
- Hydro-meteorology
- Rainfall model
language:
- iso: eng
month: '04'
oa_version: None
page: 448-467
publication: Advances in Water Resources
publication_identifier:
  issn:
  - 0309-1708
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Simulation of future climate scenarios with a weather generator
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 34
year: '2011'
...
---
_id: '3375'
abstract:
- lang: eng
  text: 'By exploiting an analogy between population genetics and statistical mechanics,
    we study the evolution of a polygenic trait under stabilizing selection, mutation
    and genetic drift. This requires us to track only four macroscopic variables,
    instead of the distribution of all the allele frequencies that influence the trait.
    These macroscopic variables are the expectations of: the trait mean and its square,
    the genetic variance, and of a measure of heterozygosity, and are derived from
    a generating function that is in turn derived by maximizing an entropy measure.
    These four macroscopics are enough to accurately describe the dynamics of the
    trait mean and of its genetic variance (and in principle of any other quantity).
    Unlike previous approaches that were based on an infinite series of moments or
    cumulants, which had to be truncated arbitrarily, our calculations provide a well-defined
    approximation procedure. We apply the framework to abrupt and gradual changes
    in the optimum, as well as to changes in the strength of stabilizing selection.
    Our approximations are surprisingly accurate, even for systems with as few as
    five loci. We find that when the effects of drift are included, the expected genetic
    variance is hardly altered by directional selection, even though it fluctuates
    in any particular instance. We also find hysteresis, showing that even after averaging
    over the microscopic variables, the macroscopic trajectories retain a memory of
    the underlying genetic states.'
article_processing_charge: No
article_type: original
author:
- first_name: Harold
  full_name: de Vladar, Harold
  id: 2A181218-F248-11E8-B48F-1D18A9856A87
  last_name: de Vladar
  orcid: 0000-0002-5985-7653
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
citation:
  ama: de Vladar H, Barton NH. The statistical mechanics of a polygenic character
    under stabilizing selection mutation and drift. <i>Journal of the Royal Society
    Interface</i>. 2011;8(58):720-739. doi:<a href="https://doi.org/10.1098/rsif.2010.0438">10.1098/rsif.2010.0438</a>
  apa: de Vladar, H., &#38; Barton, N. H. (2011). The statistical mechanics of a polygenic
    character under stabilizing selection mutation and drift. <i>Journal of the Royal
    Society Interface</i>. Royal Society. <a href="https://doi.org/10.1098/rsif.2010.0438">https://doi.org/10.1098/rsif.2010.0438</a>
  chicago: Vladar, Harold de, and Nicholas H Barton. “The Statistical Mechanics of
    a Polygenic Character under Stabilizing Selection Mutation and Drift.” <i>Journal
    of the Royal Society Interface</i>. Royal Society, 2011. <a href="https://doi.org/10.1098/rsif.2010.0438">https://doi.org/10.1098/rsif.2010.0438</a>.
  ieee: H. de Vladar and N. H. Barton, “The statistical mechanics of a polygenic character
    under stabilizing selection mutation and drift,” <i>Journal of the Royal Society
    Interface</i>, vol. 8, no. 58. Royal Society, pp. 720–739, 2011.
  ista: de Vladar H, Barton NH. 2011. The statistical mechanics of a polygenic character
    under stabilizing selection mutation and drift. Journal of the Royal Society Interface.
    8(58), 720–739.
  mla: de Vladar, Harold, and Nicholas H. Barton. “The Statistical Mechanics of a
    Polygenic Character under Stabilizing Selection Mutation and Drift.” <i>Journal
    of the Royal Society Interface</i>, vol. 8, no. 58, Royal Society, 2011, pp. 720–39,
    doi:<a href="https://doi.org/10.1098/rsif.2010.0438">10.1098/rsif.2010.0438</a>.
  short: H. de Vladar, N.H. Barton, Journal of the Royal Society Interface 8 (2011)
    720–739.
corr_author: '1'
date_created: 2018-12-11T12:02:58Z
date_published: 2011-05-01T00:00:00Z
date_updated: 2026-08-12T14:07:44Z
day: '01'
department:
- _id: NiBa
doi: 10.1098/rsif.2010.0438
ec_funded: 1
external_id:
  isi:
  - '000289671700011'
  pmid:
  - '21084341'
fulldoi: https://doi.org/10.1098/rsif.2010.0438
intvolume: '         8'
isi: 1
issue: '58'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061091/
month: '05'
oa: 1
oa_version: Submitted Version
page: 720 - 739
pmid: 1
project:
- _id: 25B07788-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '250152'
  name: Limits to selection in biology and in evolutionary computation
publication: Journal of the Royal Society Interface
publication_status: published
publisher: Royal Society
publist_id: '3232'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The statistical mechanics of a polygenic character under stabilizing selection
  mutation and drift
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2011'
...
---
_id: '10908'
abstract:
- lang: eng
  text: We present ABC, a software tool for automatically computing symbolic upper
    bounds on the number of iterations of nested program loops. The system combines
    static analysis of programs with symbolic summation techniques to derive loop
    invariant relations between program variables. Iteration bounds are obtained from
    the inferred invariants, by replacing variables with bounds on their greatest
    values. We have successfully applied ABC to a large number of examples. The derived
    symbolic bounds express non-trivial polynomial relations over loop variables.
    We also report on results to automatically infer symbolic expressions over harmonic
    numbers as upper bounds on loop iteration counts.
acknowledgement: This work was supported in part by the Swiss NSF. The fourth author
  is supported by an FWF Hertha Firnberg Research grant (T425-N23).
article_processing_charge: No
author:
- first_name: Régis
  full_name: Blanc, Régis
  last_name: Blanc
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000-0002-2985-7724
- first_name: Thibaud
  full_name: Hottelier, Thibaud
  last_name: Hottelier
- first_name: Laura
  full_name: Kovács, Laura
  last_name: Kovács
citation:
  ama: 'Blanc R, Henzinger TA, Hottelier T, Kovács L. ABC: Algebraic Bound Computation
    for loops. In: Clarke EM, Voronkov A, eds. <i>Logic for Programming, Artificial
    Intelligence, and Reasoning</i>. Vol 6355. LNCS. Berlin, Heidelberg: Springer
    Nature; 2010:103-118. doi:<a href="https://doi.org/10.1007/978-3-642-17511-4_7">10.1007/978-3-642-17511-4_7</a>'
  apa: 'Blanc, R., Henzinger, T. A., Hottelier, T., &#38; Kovács, L. (2010). ABC:
    Algebraic Bound Computation for loops. In E. M. Clarke &#38; A. Voronkov (Eds.),
    <i>Logic for Programming, Artificial Intelligence, and Reasoning</i> (Vol. 6355,
    pp. 103–118). Berlin, Heidelberg: Springer Nature. <a href="https://doi.org/10.1007/978-3-642-17511-4_7">https://doi.org/10.1007/978-3-642-17511-4_7</a>'
  chicago: 'Blanc, Régis, Thomas A Henzinger, Thibaud Hottelier, and Laura Kovács.
    “ABC: Algebraic Bound Computation for Loops.” In <i>Logic for Programming, Artificial
    Intelligence, and Reasoning</i>, edited by Edmund M Clarke and Andrei Voronkov,
    6355:103–18. LNCS. Berlin, Heidelberg: Springer Nature, 2010. <a href="https://doi.org/10.1007/978-3-642-17511-4_7">https://doi.org/10.1007/978-3-642-17511-4_7</a>.'
  ieee: 'R. Blanc, T. A. Henzinger, T. Hottelier, and L. Kovács, “ABC: Algebraic Bound
    Computation for loops,” in <i>Logic for Programming, Artificial Intelligence,
    and Reasoning</i>, Dakar, Senegal, 2010, vol. 6355, pp. 103–118.'
  ista: 'Blanc R, Henzinger TA, Hottelier T, Kovács L. 2010. ABC: Algebraic Bound
    Computation for loops. Logic for Programming, Artificial Intelligence, and Reasoning.
    LPAR: Logic for Programming, Artificial Intelligence and ReasoningLNCS vol. 6355,
    103–118.'
  mla: 'Blanc, Régis, et al. “ABC: Algebraic Bound Computation for Loops.” <i>Logic
    for Programming, Artificial Intelligence, and Reasoning</i>, edited by Edmund
    M Clarke and Andrei Voronkov, vol. 6355, Springer Nature, 2010, pp. 103–18, doi:<a
    href="https://doi.org/10.1007/978-3-642-17511-4_7">10.1007/978-3-642-17511-4_7</a>.'
  short: R. Blanc, T.A. Henzinger, T. Hottelier, L. Kovács, in:, E.M. Clarke, A. Voronkov
    (Eds.), Logic for Programming, Artificial Intelligence, and Reasoning, Springer
    Nature, Berlin, Heidelberg, 2010, pp. 103–118.
conference:
  end_date: 2010-05-01
  location: Dakar, Senegal
  name: 'LPAR: Logic for Programming, Artificial Intelligence and Reasoning'
  start_date: 2010-04-25
corr_author: '1'
date_created: 2022-03-21T08:14:35Z
date_published: 2010-05-01T00:00:00Z
date_updated: 2025-09-30T09:51:13Z
day: '01'
department:
- _id: ToHe
doi: 10.1007/978-3-642-17511-4_7
editor:
- first_name: Edmund M
  full_name: Clarke, Edmund M
  last_name: Clarke
- first_name: Andrei
  full_name: Voronkov, Andrei
  last_name: Voronkov
external_id:
  isi:
  - '000309668000007'
fulldoi: https://doi.org/10.1007/978-3-642-17511-4_7
intvolume: '      6355'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://infoscience.epfl.ch/record/186096
month: '05'
oa: 1
oa_version: Submitted Version
page: 103-118
place: Berlin, Heidelberg
publication: Logic for Programming, Artificial Intelligence, and Reasoning
publication_identifier:
  eisbn:
  - '9783642175114'
  eissn:
  - 1611-3349
  isbn:
  - '9783642175107'
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
series_title: LNCS
status: public
title: 'ABC: Algebraic Bound Computation for loops'
type: conference
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 6355
year: '2010'
...
---
_id: '10909'
abstract:
- lang: eng
  text: We address the problem of localizing homology classes, namely, finding the
    cycle representing a given class with the most concise geometric measure. We focus
    on the volume measure, that is, the 1-norm of a cycle. Two main results are presented.
    First, we prove the problem is NP-hard to approximate within any constant factor.
    Second, we prove that for homology of dimension two or higher, the problem is
    NP-hard to approximate even when the Betti number is O(1). A side effect is the
    inapproximability of the problem of computing the nonbounding cycle with the smallest
    volume, and computing cycles representing a homology basis with the minimal total
    volume. We also discuss other geometric measures (diameter and radius) and show
    their disadvantages in homology localization. Our work is restricted to homology
    over the ℤ2 field.
acknowledgement: Partially supported by the Austrian Science Fund under grantFSP-S9103-N04
  and P20134-N13.
article_processing_charge: No
author:
- first_name: Chao
  full_name: Chen, Chao
  id: 3E92416E-F248-11E8-B48F-1D18A9856A87
  last_name: Chen
- first_name: Daniel
  full_name: Freedman, Daniel
  last_name: Freedman
citation:
  ama: 'Chen C, Freedman D. Hardness results for homology localization. In: <i>Proceedings
    of the 2010 Annual ACM-SIAM Symposium on Discrete Algorithms</i>. Society for
    Industrial and Applied Mathematics; 2010:1594-1604. doi:<a href="https://doi.org/10.1137/1.9781611973075.129">10.1137/1.9781611973075.129</a>'
  apa: 'Chen, C., &#38; Freedman, D. (2010). Hardness results for homology localization.
    In <i>Proceedings of the 2010 Annual ACM-SIAM Symposium on Discrete Algorithms</i>
    (pp. 1594–1604). Austin, TX, United States: Society for Industrial and Applied
    Mathematics. <a href="https://doi.org/10.1137/1.9781611973075.129">https://doi.org/10.1137/1.9781611973075.129</a>'
  chicago: Chen, Chao, and Daniel Freedman. “Hardness Results for Homology Localization.”
    In <i>Proceedings of the 2010 Annual ACM-SIAM Symposium on Discrete Algorithms</i>,
    1594–1604. Society for Industrial and Applied Mathematics, 2010. <a href="https://doi.org/10.1137/1.9781611973075.129">https://doi.org/10.1137/1.9781611973075.129</a>.
  ieee: C. Chen and D. Freedman, “Hardness results for homology localization,” in
    <i>Proceedings of the 2010 Annual ACM-SIAM Symposium on Discrete Algorithms</i>,
    Austin, TX, United States, 2010, pp. 1594–1604.
  ista: 'Chen C, Freedman D. 2010. Hardness results for homology localization. Proceedings
    of the 2010 Annual ACM-SIAM Symposium on Discrete Algorithms. SODA: Symposium
    on Discrete Algorithms, 1594–1604.'
  mla: Chen, Chao, and Daniel Freedman. “Hardness Results for Homology Localization.”
    <i>Proceedings of the 2010 Annual ACM-SIAM Symposium on Discrete Algorithms</i>,
    Society for Industrial and Applied Mathematics, 2010, pp. 1594–604, doi:<a href="https://doi.org/10.1137/1.9781611973075.129">10.1137/1.9781611973075.129</a>.
  short: C. Chen, D. Freedman, in:, Proceedings of the 2010 Annual ACM-SIAM Symposium
    on Discrete Algorithms, Society for Industrial and Applied Mathematics, 2010,
    pp. 1594–1604.
conference:
  end_date: 2010-01-19
  location: Austin, TX, United States
  name: 'SODA: Symposium on Discrete Algorithms'
  start_date: 2010-01-17
corr_author: '1'
date_created: 2022-03-21T08:24:07Z
date_published: 2010-02-01T00:00:00Z
date_updated: 2025-09-30T09:22:32Z
day: '01'
department:
- _id: HeEd
doi: 10.1137/1.9781611973075.129
fulldoi: https://doi.org/10.1137/1.9781611973075.129
language:
- iso: eng
month: '02'
oa_version: None
page: 1594-1604
publication: Proceedings of the 2010 Annual ACM-SIAM Symposium on Discrete Algorithms
publication_identifier:
  eisbn:
  - '9781611973075'
publication_status: published
publisher: Society for Industrial and Applied Mathematics
quality_controlled: '1'
related_material:
  record:
  - id: '3267'
    relation: later_version
    status: public
scopus_import: '1'
status: public
title: Hardness results for homology localization
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2010'
...
---
_id: '11097'
abstract:
- lang: eng
  text: The nuclear envelope (NE) is a highly regulated membrane barrier that separates
    the nucleus from the cytoplasm in eukaryotic cells. It contains a large number
    of different proteins that have been implicated in chromatin organization and
    gene regulation. Although the nuclear membrane enables complex levels of gene
    expression, it also poses a challenge when it comes to cell division. To allow
    access of the mitotic spindle to chromatin, the nucleus of metazoans must completely
    disassemble during mitosis, generating the need to re-establish the nuclear compartment
    at the end of each cell division. Here, I summarize our current understanding
    of the dynamic remodeling of the NE during the cell cycle.
article_processing_charge: No
article_type: original
author:
- first_name: Martin W
  full_name: HETZER, Martin W
  id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
  last_name: HETZER
  orcid: 0000-0002-2111-992X
citation:
  ama: Hetzer M. The nuclear envelope. <i>Cold Spring Harbor Perspectives in Biology</i>.
    2010;2(3):a000539-a000539. doi:<a href="https://doi.org/10.1101/cshperspect.a000539">10.1101/cshperspect.a000539</a>
  apa: Hetzer, M. (2010). The nuclear envelope. <i>Cold Spring Harbor Perspectives
    in Biology</i>. Cold Spring Harbor Laboratory. <a href="https://doi.org/10.1101/cshperspect.a000539">https://doi.org/10.1101/cshperspect.a000539</a>
  chicago: Hetzer, Martin. “The Nuclear Envelope.” <i>Cold Spring Harbor Perspectives
    in Biology</i>. Cold Spring Harbor Laboratory, 2010. <a href="https://doi.org/10.1101/cshperspect.a000539">https://doi.org/10.1101/cshperspect.a000539</a>.
  ieee: M. Hetzer, “The nuclear envelope,” <i>Cold Spring Harbor Perspectives in Biology</i>,
    vol. 2, no. 3. Cold Spring Harbor Laboratory, pp. a000539–a000539, 2010.
  ista: Hetzer M. 2010. The nuclear envelope. Cold Spring Harbor Perspectives in Biology.
    2(3), a000539–a000539.
  mla: Hetzer, Martin. “The Nuclear Envelope.” <i>Cold Spring Harbor Perspectives
    in Biology</i>, vol. 2, no. 3, Cold Spring Harbor Laboratory, 2010, pp. a000539–a000539,
    doi:<a href="https://doi.org/10.1101/cshperspect.a000539">10.1101/cshperspect.a000539</a>.
  short: M. Hetzer, Cold Spring Harbor Perspectives in Biology 2 (2010) a000539–a000539.
date_created: 2022-04-07T07:52:49Z
date_published: 2010-02-03T00:00:00Z
date_updated: 2024-10-14T11:26:41Z
day: '03'
doi: 10.1101/cshperspect.a000539
extern: '1'
external_id:
  pmid:
  - '20300205'
fulldoi: https://doi.org/10.1101/cshperspect.a000539
intvolume: '         2'
issue: '3'
keyword:
- General Biochemistry
- Genetics and Molecular Biology
language:
- iso: eng
month: '02'
oa_version: None
page: a000539-a000539
pmid: 1
publication: Cold Spring Harbor Perspectives in Biology
publication_identifier:
  issn:
  - 1943-0264
publication_status: published
publisher: Cold Spring Harbor Laboratory
quality_controlled: '1'
scopus_import: '1'
status: public
title: The nuclear envelope
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2
year: '2010'
...
---
_id: '11098'
article_processing_charge: No
article_type: original
author:
- first_name: Martin W
  full_name: HETZER, Martin W
  id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
  last_name: HETZER
  orcid: 0000-0002-2111-992X
citation:
  ama: Hetzer M. The role of the nuclear pore complex in aging of post-mitotic cells.
    <i>Aging</i>. 2010;2(2):74-75. doi:<a href="https://doi.org/10.18632/aging.100125">10.18632/aging.100125</a>
  apa: Hetzer, M. (2010). The role of the nuclear pore complex in aging of post-mitotic
    cells. <i>Aging</i>. Impact Journals. <a href="https://doi.org/10.18632/aging.100125">https://doi.org/10.18632/aging.100125</a>
  chicago: Hetzer, Martin. “The Role of the Nuclear Pore Complex in Aging of Post-Mitotic
    Cells.” <i>Aging</i>. Impact Journals, 2010. <a href="https://doi.org/10.18632/aging.100125">https://doi.org/10.18632/aging.100125</a>.
  ieee: M. Hetzer, “The role of the nuclear pore complex in aging of post-mitotic
    cells,” <i>Aging</i>, vol. 2, no. 2. Impact Journals, pp. 74–75, 2010.
  ista: Hetzer M. 2010. The role of the nuclear pore complex in aging of post-mitotic
    cells. Aging. 2(2), 74–75.
  mla: Hetzer, Martin. “The Role of the Nuclear Pore Complex in Aging of Post-Mitotic
    Cells.” <i>Aging</i>, vol. 2, no. 2, Impact Journals, 2010, pp. 74–75, doi:<a
    href="https://doi.org/10.18632/aging.100125">10.18632/aging.100125</a>.
  short: M. Hetzer, Aging 2 (2010) 74–75.
date_created: 2022-04-07T07:52:58Z
date_published: 2010-02-01T00:00:00Z
date_updated: 2024-10-14T11:26:51Z
day: '01'
doi: 10.18632/aging.100125
extern: '1'
external_id:
  pmid:
  - '20354266'
fulldoi: https://doi.org/10.18632/aging.100125
intvolume: '         2'
issue: '2'
keyword:
- Cell Biology
- Aging
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.18632/aging.100125
month: '02'
oa: 1
oa_version: Published Version
page: 74-75
pmid: 1
publication: Aging
publication_identifier:
  issn:
  - 1945-4589
publication_status: published
publisher: Impact Journals
quality_controlled: '1'
scopus_import: '1'
status: public
title: The role of the nuclear pore complex in aging of post-mitotic cells
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2
year: '2010'
...
---
_id: '11099'
abstract:
- lang: eng
  text: Nuclear pore complexes (NPCs) serve as transport channels across the nuclear
    membrane, a double lipid bilayer that physically separates the nucleoplasm and
    cytoplasm of eukaryotic cells. New evidence suggests that the multiprotein nuclear
    pores also play a role in chromatin organization and gene expression. Given the
    importance of NPC function, it is not surprising that a growing list of human
    diseases and developmental defects have been linked to its malfunction. In order
    to fully understand the functional repertoire of NPCs and their essential role
    for nuclear organization, it is critical to determine the sequence of events that
    lead to the formation of nuclear pores. This is particularly relevant since NPC
    number, and possibly composition, are tightly linked to metabolic activity. Most
    of our knowledge is derived from NPC formation that occurs in dividing cells at
    the end of mitosis when the nuclear envelope (NE) and NPCs reform from disassembled
    precursors. However, NPC assembly also takes place during interphase into an intact
    NE. Importantly, this process is not restricted to dividing cells but also occurs
    during cell differentiation. Here, we will review aspects unique to this process,
    namely the regulation of nuclear expansion and the mechanisms of fusion between
    the outer and inner nuclear membranes. We will then discuss conserved and diverging
    mechanisms between post-mitotic and interphase assembly of the proteinaceous structure
    in light of recently published data.
article_processing_charge: No
article_type: review
author:
- first_name: Christine M.
  full_name: Doucet, Christine M.
  last_name: Doucet
- first_name: Martin W
  full_name: HETZER, Martin W
  id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
  last_name: HETZER
  orcid: 0000-0002-2111-992X
citation:
  ama: Doucet CM, Hetzer M. Nuclear pore biogenesis into an intact nuclear envelope.
    <i>Chromosoma</i>. 2010;119:469-477. doi:<a href="https://doi.org/10.1007/s00412-010-0289-2">10.1007/s00412-010-0289-2</a>
  apa: Doucet, C. M., &#38; Hetzer, M. (2010). Nuclear pore biogenesis into an intact
    nuclear envelope. <i>Chromosoma</i>. Springer Nature. <a href="https://doi.org/10.1007/s00412-010-0289-2">https://doi.org/10.1007/s00412-010-0289-2</a>
  chicago: Doucet, Christine M., and Martin Hetzer. “Nuclear Pore Biogenesis into
    an Intact Nuclear Envelope.” <i>Chromosoma</i>. Springer Nature, 2010. <a href="https://doi.org/10.1007/s00412-010-0289-2">https://doi.org/10.1007/s00412-010-0289-2</a>.
  ieee: C. M. Doucet and M. Hetzer, “Nuclear pore biogenesis into an intact nuclear
    envelope,” <i>Chromosoma</i>, vol. 119. Springer Nature, pp. 469–477, 2010.
  ista: Doucet CM, Hetzer M. 2010. Nuclear pore biogenesis into an intact nuclear
    envelope. Chromosoma. 119, 469–477.
  mla: Doucet, Christine M., and Martin Hetzer. “Nuclear Pore Biogenesis into an Intact
    Nuclear Envelope.” <i>Chromosoma</i>, vol. 119, Springer Nature, 2010, pp. 469–77,
    doi:<a href="https://doi.org/10.1007/s00412-010-0289-2">10.1007/s00412-010-0289-2</a>.
  short: C.M. Doucet, M. Hetzer, Chromosoma 119 (2010) 469–477.
date_created: 2022-04-07T07:53:12Z
date_published: 2010-10-01T00:00:00Z
date_updated: 2024-10-14T11:27:07Z
day: '01'
doi: 10.1007/s00412-010-0289-2
extern: '1'
external_id:
  pmid:
  - '20721671'
fulldoi: https://doi.org/10.1007/s00412-010-0289-2
intvolume: '       119'
keyword:
- Genetics (clinical)
- Genetics
language:
- iso: eng
month: '10'
oa_version: None
page: 469-477
pmid: 1
publication: Chromosoma
publication_identifier:
  eissn:
  - 1432-0886
  issn:
  - 0009-5915
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Nuclear pore biogenesis into an intact nuclear envelope
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 119
year: '2010'
...
---
_id: '11101'
abstract:
- lang: eng
  text: In metazoa, nuclear pore complexes (NPCs) assemble from disassembled precursors
    into a reforming nuclear envelope (NE) at the end of mitosis and into growing
    intact NEs during interphase. Here, we show via RNAi-mediated knockdown that ELYS,
    a nucleoporin critical for the recruitment of the essential Nup107/160 complex
    to chromatin, is required for NPC assembly at the end of mitosis but not during
    interphase. Conversely, the transmembrane nucleoporin POM121 is critical for the
    incorporation of the Nup107/160 complex into new assembly sites specifically during
    interphase. Strikingly, recruitment of the Nup107/160 complex to an intact NE
    involves a membrane curvature-sensing domain of its constituent Nup133, which
    is not required for postmitotic NPC formation. Our results suggest that in organisms
    with open mitosis, NPCs assemble via two distinct mechanisms to accommodate cell
    cycle-dependent differences in NE topology.
article_processing_charge: No
article_type: original
author:
- first_name: Christine M.
  full_name: Doucet, Christine M.
  last_name: Doucet
- first_name: Jessica A.
  full_name: Talamas, Jessica A.
  last_name: Talamas
- first_name: Martin W
  full_name: HETZER, Martin W
  id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
  last_name: HETZER
  orcid: 0000-0002-2111-992X
citation:
  ama: Doucet CM, Talamas JA, Hetzer M. Cell cycle-dependent differences in nuclear
    pore complex assembly in metazoa. <i>Cell</i>. 2010;141(6):1030-1041. doi:<a href="https://doi.org/10.1016/j.cell.2010.04.036">10.1016/j.cell.2010.04.036</a>
  apa: Doucet, C. M., Talamas, J. A., &#38; Hetzer, M. (2010). Cell cycle-dependent
    differences in nuclear pore complex assembly in metazoa. <i>Cell</i>. Elsevier.
    <a href="https://doi.org/10.1016/j.cell.2010.04.036">https://doi.org/10.1016/j.cell.2010.04.036</a>
  chicago: Doucet, Christine M., Jessica A. Talamas, and Martin Hetzer. “Cell Cycle-Dependent
    Differences in Nuclear Pore Complex Assembly in Metazoa.” <i>Cell</i>. Elsevier,
    2010. <a href="https://doi.org/10.1016/j.cell.2010.04.036">https://doi.org/10.1016/j.cell.2010.04.036</a>.
  ieee: C. M. Doucet, J. A. Talamas, and M. Hetzer, “Cell cycle-dependent differences
    in nuclear pore complex assembly in metazoa,” <i>Cell</i>, vol. 141, no. 6. Elsevier,
    pp. 1030–1041, 2010.
  ista: Doucet CM, Talamas JA, Hetzer M. 2010. Cell cycle-dependent differences in
    nuclear pore complex assembly in metazoa. Cell. 141(6), 1030–1041.
  mla: Doucet, Christine M., et al. “Cell Cycle-Dependent Differences in Nuclear Pore
    Complex Assembly in Metazoa.” <i>Cell</i>, vol. 141, no. 6, Elsevier, 2010, pp.
    1030–41, doi:<a href="https://doi.org/10.1016/j.cell.2010.04.036">10.1016/j.cell.2010.04.036</a>.
  short: C.M. Doucet, J.A. Talamas, M. Hetzer, Cell 141 (2010) 1030–1041.
date_created: 2022-04-07T07:53:29Z
date_published: 2010-06-11T00:00:00Z
date_updated: 2024-10-14T11:28:00Z
day: '11'
doi: 10.1016/j.cell.2010.04.036
extern: '1'
external_id:
  pmid:
  - '20550937'
fulldoi: https://doi.org/10.1016/j.cell.2010.04.036
intvolume: '       141'
issue: '6'
keyword:
- General Biochemistry
- Genetics and Molecular Biology
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.cell.2010.04.036
month: '06'
oa: 1
oa_version: Published Version
page: 1030-1041
pmid: 1
publication: Cell
publication_identifier:
  issn:
  - 0092-8674
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Cell cycle-dependent differences in nuclear pore complex assembly in metazoa
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 141
year: '2010'
...
---
_id: '11102'
abstract:
- lang: eng
  text: Nuclear pore complexes have recently been shown to play roles in gene activation;
    however their potential involvement in metazoan transcription remains unclear.
    Here we show that the nucleoporins Sec13, Nup98, and Nup88, as well as a group
    of FG-repeat nucleoporins, bind to the Drosophila genome at functionally distinct
    loci that often do not represent nuclear envelope contact sites. Whereas Nup88
    localizes to silent loci, Sec13, Nup98, and a subset of FG-repeat nucleoporins
    bind to developmentally regulated genes undergoing transcription induction. Strikingly,
    RNAi-mediated knockdown of intranuclear Sec13 and Nup98 specifically inhibits
    transcription of their target genes and prevents efficient reactivation of transcription
    after heat shock, suggesting an essential role of NPC components in regulating
    complex gene expression programs of multicellular organisms.
article_processing_charge: No
article_type: original
author:
- first_name: Maya
  full_name: Capelson, Maya
  last_name: Capelson
- first_name: Yun
  full_name: Liang, Yun
  last_name: Liang
- first_name: Roberta
  full_name: Schulte, Roberta
  last_name: Schulte
- first_name: William
  full_name: Mair, William
  last_name: Mair
- first_name: Ulrich
  full_name: Wagner, Ulrich
  last_name: Wagner
- first_name: Martin W
  full_name: HETZER, Martin W
  id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
  last_name: HETZER
  orcid: 0000-0002-2111-992X
citation:
  ama: Capelson M, Liang Y, Schulte R, Mair W, Wagner U, Hetzer M. Chromatin-bound
    nuclear pore components regulate gene expression in higher eukaryotes. <i>Cell</i>.
    2010;140(3):372-383. doi:<a href="https://doi.org/10.1016/j.cell.2009.12.054">10.1016/j.cell.2009.12.054</a>
  apa: Capelson, M., Liang, Y., Schulte, R., Mair, W., Wagner, U., &#38; Hetzer, M.
    (2010). Chromatin-bound nuclear pore components regulate gene expression in higher
    eukaryotes. <i>Cell</i>. Elsevier. <a href="https://doi.org/10.1016/j.cell.2009.12.054">https://doi.org/10.1016/j.cell.2009.12.054</a>
  chicago: Capelson, Maya, Yun Liang, Roberta Schulte, William Mair, Ulrich Wagner,
    and Martin Hetzer. “Chromatin-Bound Nuclear Pore Components Regulate Gene Expression
    in Higher Eukaryotes.” <i>Cell</i>. Elsevier, 2010. <a href="https://doi.org/10.1016/j.cell.2009.12.054">https://doi.org/10.1016/j.cell.2009.12.054</a>.
  ieee: M. Capelson, Y. Liang, R. Schulte, W. Mair, U. Wagner, and M. Hetzer, “Chromatin-bound
    nuclear pore components regulate gene expression in higher eukaryotes,” <i>Cell</i>,
    vol. 140, no. 3. Elsevier, pp. 372–383, 2010.
  ista: Capelson M, Liang Y, Schulte R, Mair W, Wagner U, Hetzer M. 2010. Chromatin-bound
    nuclear pore components regulate gene expression in higher eukaryotes. Cell. 140(3),
    372–383.
  mla: Capelson, Maya, et al. “Chromatin-Bound Nuclear Pore Components Regulate Gene
    Expression in Higher Eukaryotes.” <i>Cell</i>, vol. 140, no. 3, Elsevier, 2010,
    pp. 372–83, doi:<a href="https://doi.org/10.1016/j.cell.2009.12.054">10.1016/j.cell.2009.12.054</a>.
  short: M. Capelson, Y. Liang, R. Schulte, W. Mair, U. Wagner, M. Hetzer, Cell 140
    (2010) 372–383.
date_created: 2022-04-07T07:53:36Z
date_published: 2010-02-05T00:00:00Z
date_updated: 2024-10-14T11:28:14Z
day: '05'
doi: 10.1016/j.cell.2009.12.054
extern: '1'
external_id:
  pmid:
  - '20144761'
fulldoi: https://doi.org/10.1016/j.cell.2009.12.054
intvolume: '       140'
issue: '3'
keyword:
- General Biochemistry
- Genetics and Molecular Biology
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.cell.2009.12.054
month: '02'
oa: 1
oa_version: Published Version
page: 372-383
pmid: 1
publication: Cell
publication_identifier:
  issn:
  - 0092-8674
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Chromatin-bound nuclear pore components regulate gene expression in higher
  eukaryotes
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 140
year: '2010'
...
---
_id: '11753'
abstract:
- lang: eng
  text: Ferroelectric ceramic materials have a wide range of applications because
    of their piezoelectric and pyroelectric properties. One of their most important
    physical properties is the specific heat. In this study, the specific heats of
    a series of lead-zirconate-titanate (PZT) compositions in the vicinity of the
    morphotropic phase boundary (MPB) were measured. The temperature range was from
    1.8 to 300 K. It is believed that these are the lowest temperature measurements
    ever made on PZT. Differences between the specific heats of the different compositions
    were very small. However, the calculated Debye temperatures were slightly different.
    The results are useful in computing design parameters for technical devices.
article_number: '5568033'
article_processing_charge: No
author:
- first_name: S. B.
  full_name: Lang, S. B.
  last_name: Lang
- first_name: J. C.
  full_name: Lashley, J. C.
  last_name: Lashley
- first_name: Kimberly A
  full_name: Modic, Kimberly A
  id: 13C26AC0-EB69-11E9-87C6-5F3BE6697425
  last_name: Modic
  orcid: 0000-0001-9760-3147
- first_name: R. A.
  full_name: Fisher, R. A.
  last_name: Fisher
- first_name: W. M.
  full_name: Zhu, W. M.
  last_name: Zhu
- first_name: Z. G.
  full_name: Ye, Z. G.
  last_name: Ye
citation:
  ama: 'Lang SB, Lashley JC, Modic KA, Fisher RA, Zhu WM, Ye ZG. Specific heat of
    a ferroelectric PZT ceramic at the morphotropic phase boundary. In: <i>Proceedings
    of the 2010 IEEE International Conference on Solid Dielectrics</i>. Institute
    of Electrical and Electronics Engineers; 2010. doi:<a href="https://doi.org/10.1109/icsd.2010.5568033">10.1109/icsd.2010.5568033</a>'
  apa: 'Lang, S. B., Lashley, J. C., Modic, K. A., Fisher, R. A., Zhu, W. M., &#38;
    Ye, Z. G. (2010). Specific heat of a ferroelectric PZT ceramic at the morphotropic
    phase boundary. In <i>Proceedings of the 2010 IEEE International Conference on
    Solid Dielectrics</i>. Potsdam, Germany: Institute of Electrical and Electronics
    Engineers. <a href="https://doi.org/10.1109/icsd.2010.5568033">https://doi.org/10.1109/icsd.2010.5568033</a>'
  chicago: Lang, S. B., J. C. Lashley, Kimberly A Modic, R. A. Fisher, W. M. Zhu,
    and Z. G. Ye. “Specific Heat of a Ferroelectric PZT Ceramic at the Morphotropic
    Phase Boundary.” In <i>Proceedings of the 2010 IEEE International Conference on
    Solid Dielectrics</i>. Institute of Electrical and Electronics Engineers, 2010.
    <a href="https://doi.org/10.1109/icsd.2010.5568033">https://doi.org/10.1109/icsd.2010.5568033</a>.
  ieee: S. B. Lang, J. C. Lashley, K. A. Modic, R. A. Fisher, W. M. Zhu, and Z. G.
    Ye, “Specific heat of a ferroelectric PZT ceramic at the morphotropic phase boundary,”
    in <i>Proceedings of the 2010 IEEE International Conference on Solid Dielectrics</i>,
    Potsdam, Germany, 2010.
  ista: 'Lang SB, Lashley JC, Modic KA, Fisher RA, Zhu WM, Ye ZG. 2010. Specific heat
    of a ferroelectric PZT ceramic at the morphotropic phase boundary. Proceedings
    of the 2010 IEEE International Conference on Solid Dielectrics. ICSD: International
    Conference on Solid Dielectrics, 5568033.'
  mla: Lang, S. B., et al. “Specific Heat of a Ferroelectric PZT Ceramic at the Morphotropic
    Phase Boundary.” <i>Proceedings of the 2010 IEEE International Conference on Solid
    Dielectrics</i>, 5568033, Institute of Electrical and Electronics Engineers, 2010,
    doi:<a href="https://doi.org/10.1109/icsd.2010.5568033">10.1109/icsd.2010.5568033</a>.
  short: S.B. Lang, J.C. Lashley, K.A. Modic, R.A. Fisher, W.M. Zhu, Z.G. Ye, in:,
    Proceedings of the 2010 IEEE International Conference on Solid Dielectrics, Institute
    of Electrical and Electronics Engineers, 2010.
conference:
  end_date: 2010-06-09
  location: Potsdam, Germany
  name: 'ICSD: International Conference on Solid Dielectrics'
  start_date: 2010-06-04
date_created: 2022-08-08T09:00:17Z
date_published: 2010-06-01T00:00:00Z
date_updated: 2023-02-21T16:26:58Z
day: '01'
doi: 10.1109/icsd.2010.5568033
extern: '1'
fulldoi: https://doi.org/10.1109/icsd.2010.5568033
language:
- iso: eng
month: '06'
oa_version: None
publication: Proceedings of the 2010 IEEE International Conference on Solid Dielectrics
publication_identifier:
  eissn:
  - 2159-1687
  issn:
  - 1553-5282
publication_status: published
publisher: Institute of Electrical and Electronics Engineers
quality_controlled: '1'
related_material:
  record:
  - id: '11754'
    relation: earlier_version
    status: public
scopus_import: '1'
status: public
title: Specific heat of a ferroelectric PZT ceramic at the morphotropic phase boundary
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2010'
...
---
_id: '11754'
abstract:
- lang: eng
  text: Ferroelectric ceramic materials have a wide range of applications because
    of their piezoelectric and pyroelectric properties. One of their most important
    physical properties is the specific heat. In this study, the specific heats of
    a series of lead-zirconate-titanate (PZT) compositions in the vicinity of the
    morphotropic phase boundary (MPB) were measured. The temperature range was from
    1.8 to 300 K. It is believed that these are the lowest temperature measurements
    ever made on PZT. Differences between the specific heats of the different compositions
    were very small. However, the calculated Debye temperatures were slightly different.
    The results are useful in computing design parameters for technical devices.
article_number: '5476345'
article_processing_charge: No
author:
- first_name: S.B.
  full_name: Lang, S.B.
  last_name: Lang
- first_name: J.C.
  full_name: Lashley, J.C.
  last_name: Lashley
- first_name: Kimberly A
  full_name: Modic, Kimberly A
  id: 13C26AC0-EB69-11E9-87C6-5F3BE6697425
  last_name: Modic
  orcid: 0000-0001-9760-3147
- first_name: R.A.
  full_name: Fisher, R.A.
  last_name: Fisher
- first_name: W.M.
  full_name: Zhu, W.M.
  last_name: Zhu
- first_name: Z.G.
  full_name: Ye, Z.G.
  last_name: Ye
citation:
  ama: 'Lang SB, Lashley JC, Modic KA, Fisher RA, Zhu WM, Ye ZG. Specific heat of
    a ferroelectric PZT ceramic at the morphotropic phase boundary. In: <i>15th IEEE
    Mediterranean Electrotechnical Conference</i>. Institute of Electrical and Electronics
    Engineers; 2010. doi:<a href="https://doi.org/10.1109/melcon.2010.5476345">10.1109/melcon.2010.5476345</a>'
  apa: 'Lang, S. B., Lashley, J. C., Modic, K. A., Fisher, R. A., Zhu, W. M., &#38;
    Ye, Z. G. (2010). Specific heat of a ferroelectric PZT ceramic at the morphotropic
    phase boundary. In <i>15th IEEE Mediterranean Electrotechnical Conference</i>.
    Valletta, Malta: Institute of Electrical and Electronics Engineers. <a href="https://doi.org/10.1109/melcon.2010.5476345">https://doi.org/10.1109/melcon.2010.5476345</a>'
  chicago: Lang, S.B., J.C. Lashley, Kimberly A Modic, R.A. Fisher, W.M. Zhu, and
    Z.G. Ye. “Specific Heat of a Ferroelectric PZT Ceramic at the Morphotropic Phase
    Boundary.” In <i>15th IEEE Mediterranean Electrotechnical Conference</i>. Institute
    of Electrical and Electronics Engineers, 2010. <a href="https://doi.org/10.1109/melcon.2010.5476345">https://doi.org/10.1109/melcon.2010.5476345</a>.
  ieee: S. B. Lang, J. C. Lashley, K. A. Modic, R. A. Fisher, W. M. Zhu, and Z. G.
    Ye, “Specific heat of a ferroelectric PZT ceramic at the morphotropic phase boundary,”
    in <i>15th IEEE Mediterranean Electrotechnical Conference</i>, Valletta, Malta,
    2010.
  ista: 'Lang SB, Lashley JC, Modic KA, Fisher RA, Zhu WM, Ye ZG. 2010. Specific heat
    of a ferroelectric PZT ceramic at the morphotropic phase boundary. 15th IEEE Mediterranean
    Electrotechnical Conference. MELECON: Mediterranean Electrotechnical Conference,
    5476345.'
  mla: Lang, S. B., et al. “Specific Heat of a Ferroelectric PZT Ceramic at the Morphotropic
    Phase Boundary.” <i>15th IEEE Mediterranean Electrotechnical Conference</i>, 5476345,
    Institute of Electrical and Electronics Engineers, 2010, doi:<a href="https://doi.org/10.1109/melcon.2010.5476345">10.1109/melcon.2010.5476345</a>.
  short: S.B. Lang, J.C. Lashley, K.A. Modic, R.A. Fisher, W.M. Zhu, Z.G. Ye, in:,
    15th IEEE Mediterranean Electrotechnical Conference, Institute of Electrical and
    Electronics Engineers, 2010.
conference:
  end_date: 2010-04-28
  location: Valletta, Malta
  name: 'MELECON: Mediterranean Electrotechnical Conference'
  start_date: 2010-04-26
date_created: 2022-08-08T09:11:43Z
date_published: 2010-04-26T00:00:00Z
date_updated: 2023-02-21T16:26:55Z
day: '26'
doi: 10.1109/melcon.2010.5476345
extern: '1'
fulldoi: https://doi.org/10.1109/melcon.2010.5476345
language:
- iso: eng
month: '04'
oa_version: None
publication: 15th IEEE Mediterranean Electrotechnical Conference
publication_identifier:
  isbn:
  - 978-142445795-3
publication_status: published
publisher: Institute of Electrical and Electronics Engineers
quality_controlled: '1'
related_material:
  record:
  - id: '11753'
    relation: later_version
    status: public
scopus_import: '1'
status: public
title: Specific heat of a ferroelectric PZT ceramic at the morphotropic phase boundary
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2010'
...
---
_id: '11797'
abstract:
- lang: eng
  text: "Inspired by online ad allocation, we study online stochastic packing integer
    programs from theoretical and practical standpoints. We first present a near-optimal
    online algorithm for a general class of packing integer programs which model various
    online resource allocation problems including online variants of routing, ad allocations,
    generalized assignment, and combinatorial auctions. As our main theoretical result,
    we prove that a simple dual training-based algorithm achieves a (1 − o(1))-approximation
    guarantee in the random order stochastic model. This is a significant improvement
    over logarithmic or constant-factor approximations for the adversarial variants
    of the same problems (e.g. factor 1−1\U0001D452 for online ad allocation, and
    log(m) for online routing). We then focus on the online display ad allocation
    problem and study the efficiency and fairness of various training-based and online
    allocation algorithms on data sets collected from real-life display ad allocation
    system. Our experimental evaluation confirms the effectiveness of training-based
    algorithms on real data sets, and also indicates an intrinsic trade-off between
    fairness and efficiency."
alternative_title:
- LNCS
article_processing_charge: No
arxiv: 1
author:
- first_name: Jon
  full_name: Feldman, Jon
  last_name: Feldman
- first_name: Monika H
  full_name: Henzinger, Monika H
  id: 540c9bbd-f2de-11ec-812d-d04a5be85630
  last_name: Henzinger
  orcid: 0000-0002-5008-6530
- first_name: Nitish
  full_name: Korula, Nitish
  last_name: Korula
- first_name: Vahab S.
  full_name: Mirrokni, Vahab S.
  last_name: Mirrokni
- first_name: Cliff
  full_name: Stein, Cliff
  last_name: Stein
citation:
  ama: 'Feldman J, Henzinger M, Korula N, Mirrokni VS, Stein C. Online stochastic
    packing applied to display ad allocation. In: <i>18th Annual European Symposium
    on Algorithms</i>. Vol 6346. Springer Nature; 2010:182–194. doi:<a href="https://doi.org/10.1007/978-3-642-15775-2_16">10.1007/978-3-642-15775-2_16</a>'
  apa: 'Feldman, J., Henzinger, M., Korula, N., Mirrokni, V. S., &#38; Stein, C. (2010).
    Online stochastic packing applied to display ad allocation. In <i>18th Annual
    European Symposium on Algorithms</i> (Vol. 6346, pp. 182–194). Liverpool, United
    Kingdom: Springer Nature. <a href="https://doi.org/10.1007/978-3-642-15775-2_16">https://doi.org/10.1007/978-3-642-15775-2_16</a>'
  chicago: Feldman, Jon, Monika Henzinger, Nitish Korula, Vahab S. Mirrokni, and Cliff
    Stein. “Online Stochastic Packing Applied to Display Ad Allocation.” In <i>18th
    Annual European Symposium on Algorithms</i>, 6346:182–194. Springer Nature, 2010.
    <a href="https://doi.org/10.1007/978-3-642-15775-2_16">https://doi.org/10.1007/978-3-642-15775-2_16</a>.
  ieee: J. Feldman, M. Henzinger, N. Korula, V. S. Mirrokni, and C. Stein, “Online
    stochastic packing applied to display ad allocation,” in <i>18th Annual European
    Symposium on Algorithms</i>, Liverpool, United Kingdom, 2010, vol. 6346, pp. 182–194.
  ista: 'Feldman J, Henzinger M, Korula N, Mirrokni VS, Stein C. 2010. Online stochastic
    packing applied to display ad allocation. 18th Annual European Symposium on Algorithms.
    ESA: European Symposium on Algorithms, LNCS, vol. 6346, 182–194.'
  mla: Feldman, Jon, et al. “Online Stochastic Packing Applied to Display Ad Allocation.”
    <i>18th Annual European Symposium on Algorithms</i>, vol. 6346, Springer Nature,
    2010, pp. 182–194, doi:<a href="https://doi.org/10.1007/978-3-642-15775-2_16">10.1007/978-3-642-15775-2_16</a>.
  short: J. Feldman, M. Henzinger, N. Korula, V.S. Mirrokni, C. Stein, in:, 18th Annual
    European Symposium on Algorithms, Springer Nature, 2010, pp. 182–194.
conference:
  end_date: 2010-09-08
  location: Liverpool, United Kingdom
  name: 'ESA: European Symposium on Algorithms'
  start_date: 2010-09-06
date_created: 2022-08-11T12:14:20Z
date_published: 2010-09-01T00:00:00Z
date_updated: 2024-11-06T12:13:14Z
day: '01'
doi: 10.1007/978-3-642-15775-2_16
extern: '1'
external_id:
  arxiv:
  - '1001.5076'
fulldoi: https://doi.org/10.1007/978-3-642-15775-2_16
intvolume: '      6346'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1001.5076
month: '09'
oa: 1
oa_version: Preprint
page: 182–194
publication: 18th Annual European Symposium on Algorithms
publication_identifier:
  isbn:
  - '3642157742'
  issn:
  - 1611-3349
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Online stochastic packing applied to display ad allocation
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6346
year: '2010'
...
---
_id: '11798'
abstract:
- lang: eng
  text: Starting with two models fifty years ago, the discrete marriage game [1] and
    the continuous assignment game [2], the study of stable matchings has evolved
    into a rich theory with applications in many areas. Most notably, it has lead
    to a number of truthful mechanisms that have seen a recent rejuvenation in the
    context of sponsored search. In this paper we survey the history of these problems
    and provide several links to ongoing research in the field.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Paul
  full_name: Dütting, Paul
  last_name: Dütting
- first_name: Monika H
  full_name: Henzinger, Monika H
  id: 540c9bbd-f2de-11ec-812d-d04a5be85630
  last_name: Henzinger
  orcid: 0000-0002-5008-6530
citation:
  ama: 'Dütting P, Henzinger M. Mechanisms for the marriage and the assignment game.
    In: <i>7th International Conference on Algorithms and Complexity</i>. Vol 6078.
    Springer Nature; 2010:6–12. doi:<a href="https://doi.org/10.1007/978-3-642-13073-1_2">10.1007/978-3-642-13073-1_2</a>'
  apa: 'Dütting, P., &#38; Henzinger, M. (2010). Mechanisms for the marriage and the
    assignment game. In <i>7th International Conference on Algorithms and Complexity</i>
    (Vol. 6078, pp. 6–12). Rome, Italy: Springer Nature. <a href="https://doi.org/10.1007/978-3-642-13073-1_2">https://doi.org/10.1007/978-3-642-13073-1_2</a>'
  chicago: Dütting, Paul, and Monika Henzinger. “Mechanisms for the Marriage and the
    Assignment Game.” In <i>7th International Conference on Algorithms and Complexity</i>,
    6078:6–12. Springer Nature, 2010. <a href="https://doi.org/10.1007/978-3-642-13073-1_2">https://doi.org/10.1007/978-3-642-13073-1_2</a>.
  ieee: P. Dütting and M. Henzinger, “Mechanisms for the marriage and the assignment
    game,” in <i>7th International Conference on Algorithms and Complexity</i>, Rome,
    Italy, 2010, vol. 6078, pp. 6–12.
  ista: 'Dütting P, Henzinger M. 2010. Mechanisms for the marriage and the assignment
    game. 7th International Conference on Algorithms and Complexity. CIAC: International
    Conference on Algorithms and Complexity, LNCS, vol. 6078, 6–12.'
  mla: Dütting, Paul, and Monika Henzinger. “Mechanisms for the Marriage and the Assignment
    Game.” <i>7th International Conference on Algorithms and Complexity</i>, vol.
    6078, Springer Nature, 2010, pp. 6–12, doi:<a href="https://doi.org/10.1007/978-3-642-13073-1_2">10.1007/978-3-642-13073-1_2</a>.
  short: P. Dütting, M. Henzinger, in:, 7th International Conference on Algorithms
    and Complexity, Springer Nature, 2010, pp. 6–12.
conference:
  end_date: 2010-05-28
  location: Rome, Italy
  name: 'CIAC: International Conference on Algorithms and Complexity'
  start_date: 2010-05-26
date_created: 2022-08-11T12:27:43Z
date_published: 2010-05-01T00:00:00Z
date_updated: 2024-11-06T08:15:13Z
day: '01'
doi: 10.1007/978-3-642-13073-1_2
extern: '1'
fulldoi: https://doi.org/10.1007/978-3-642-13073-1_2
intvolume: '      6078'
language:
- iso: eng
month: '05'
oa_version: None
page: 6–12
publication: 7th International Conference on Algorithms and Complexity
publication_identifier:
  isbn:
  - '9783642130724'
  issn:
  - 1611-3349
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mechanisms for the marriage and the assignment game
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6078
year: '2010'
...
---
_id: '11838'
abstract:
- lang: eng
  text: Two-sided matching markets play a prominent role in economic theory. A prime
    example of such a market is the sponsored search market where $n$ advertisers
    compete for the assignment of one of $k$ sponsored search results, also known
    as ``slots'', for certain keywords they are interested in. Here, as in other markets
    of that kind, market equilibria correspond to stable matchings. In this paper,
    we show how to modify Kuhn's Hungarian Method (Kuhn, 1955) so that it finds an
    optimal stable matching between advertisers and advertising slots in settings
    with generalized linear utilities, per-bidder-item reserve prices, and per-bidder-item
    maximum prices. The only algorithm for this problem presented so far (Aggarwal
    et al., 2009) requires the market to be in ''general position''. We do not make
    this assumption.
alternative_title:
- LIPIcs
article_processing_charge: No
arxiv: 1
author:
- first_name: Paul
  full_name: Dütting, Paul
  last_name: Dütting
- first_name: Monika H
  full_name: Henzinger, Monika H
  id: 540c9bbd-f2de-11ec-812d-d04a5be85630
  last_name: Henzinger
  orcid: 0000-0002-5008-6530
- first_name: Ingmar
  full_name: Weber, Ingmar
  last_name: Weber
citation:
  ama: 'Dütting P, Henzinger M, Weber I. Sponsored search, market equilibria, and
    the Hungarian Method. In: <i>27th International Symposium on Theoretical Aspects
    of Computer Science</i>. Vol 5. Schloss Dagstuhl - Leibniz-Zentrum für Informatik;
    2010:287-298. doi:<a href="https://doi.org/10.4230/LIPICS.STACS.2010.2463">10.4230/LIPICS.STACS.2010.2463</a>'
  apa: 'Dütting, P., Henzinger, M., &#38; Weber, I. (2010). Sponsored search, market
    equilibria, and the Hungarian Method. In <i>27th International Symposium on Theoretical
    Aspects of Computer Science</i> (Vol. 5, pp. 287–298). Nancy, France: Schloss
    Dagstuhl - Leibniz-Zentrum für Informatik. <a href="https://doi.org/10.4230/LIPICS.STACS.2010.2463">https://doi.org/10.4230/LIPICS.STACS.2010.2463</a>'
  chicago: Dütting, Paul, Monika Henzinger, and Ingmar Weber. “Sponsored Search, Market
    Equilibria, and the Hungarian Method.” In <i>27th International Symposium on Theoretical
    Aspects of Computer Science</i>, 5:287–98. Schloss Dagstuhl - Leibniz-Zentrum
    für Informatik, 2010. <a href="https://doi.org/10.4230/LIPICS.STACS.2010.2463">https://doi.org/10.4230/LIPICS.STACS.2010.2463</a>.
  ieee: P. Dütting, M. Henzinger, and I. Weber, “Sponsored search, market equilibria,
    and the Hungarian Method,” in <i>27th International Symposium on Theoretical Aspects
    of Computer Science</i>, Nancy, France, 2010, vol. 5, pp. 287–298.
  ista: 'Dütting P, Henzinger M, Weber I. 2010. Sponsored search, market equilibria,
    and the Hungarian Method. 27th International Symposium on Theoretical Aspects
    of Computer Science. STACS: Symposium on Theoretical Aspects of Computer Science,
    LIPIcs, vol. 5, 287–298.'
  mla: Dütting, Paul, et al. “Sponsored Search, Market Equilibria, and the Hungarian
    Method.” <i>27th International Symposium on Theoretical Aspects of Computer Science</i>,
    vol. 5, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2010, pp. 287–98, doi:<a
    href="https://doi.org/10.4230/LIPICS.STACS.2010.2463">10.4230/LIPICS.STACS.2010.2463</a>.
  short: P. Dütting, M. Henzinger, I. Weber, in:, 27th International Symposium on
    Theoretical Aspects of Computer Science, Schloss Dagstuhl - Leibniz-Zentrum für
    Informatik, 2010, pp. 287–298.
conference:
  end_date: 2010-03-06
  location: Nancy, France
  name: 'STACS: Symposium on Theoretical Aspects of Computer Science'
  start_date: 2010-03-04
date_created: 2022-08-12T11:45:49Z
date_published: 2010-03-09T00:00:00Z
date_updated: 2024-11-06T11:58:41Z
day: '09'
doi: 10.4230/LIPICS.STACS.2010.2463
extern: '1'
external_id:
  arxiv:
  - '0912.1934'
fulldoi: https://doi.org/10.4230/LIPICS.STACS.2010.2463
intvolume: '         5'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.4230/LIPIcs.STACS.2010.2463
month: '03'
oa: 1
oa_version: Published Version
page: 287-298
publication: 27th International Symposium on Theoretical Aspects of Computer Science
publication_identifier:
  isbn:
  - 978-3-939897-16-3
  issn:
  - 1868-8969
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
quality_controlled: '1'
related_material:
  record:
  - id: '11838'
    relation: earlier_version
    status: public
scopus_import: '1'
status: public
title: Sponsored search, market equilibria, and the Hungarian Method
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2010'
...
