---
_id: '1764'
abstract:
- lang: eng
  text: Quantum theory predicts that empty space is not truly empty. Even in the absence
    of any particles or radiation, in pure vacuum, virtual particles are constantly
    created and annihilated. In an electromagnetic field, the presence of virtual
    photons manifests itself as a small renormalization of the energy of a quantum
    system, known as the Lamb shift. We present an experimental observation of the
    Lamb shift in a solid-state system. The strong dispersive coupling of a superconducting
    electronic circuit acting as a quantum bit (qubit) to the vacuum field in a transmission-line
    resonator leads to measurable Lamb shifts of up to 1.4% of the qubit transition
    frequency. The qubit is also observed to couple more strongly to the vacuum field
    than to a single photon inside the cavity, an effect that is explained by taking
    into account the limited anharmonicity of the higher excited qubit states.
acknowledgement: This work was supported by the Swiss National Science Foundation
  and ETHZ. P.J.L. was supported by the European Commission with a Marie Curie Intra-European
  Fellowship. A.B. was supported by the Natural Sciences and Engineering Research
  Council of Canada, Canadian Institute for Advanced Research, and Fonds Québécois
  de la Recherche sur la Nature et les Technologies
author:
- first_name: A
  full_name: Fragner, A
  last_name: Fragner
- first_name: M
  full_name: Göppl, M
  last_name: Göppl
- first_name: Johannes M
  full_name: Johannes Fink
  id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
  last_name: Fink
  orcid: 0000-0001-8112-028X
- first_name: Matthias
  full_name: Baur, Matthias P
  last_name: Baur
- first_name: R
  full_name: Bianchetti, R
  last_name: Bianchetti
- first_name: Peter
  full_name: Leek, Peter J
  last_name: Leek
- first_name: Alexandre
  full_name: Blais, Alexandre
  last_name: Blais
- first_name: Andreas
  full_name: Wallraff, Andreas
  last_name: Wallraff
citation:
  ama: Fragner A, Göppl M, Fink JM, et al. Resolving vacuum fluctuations in an electrical
    circuit by measuring the lamb shift. <i>Science</i>. 2008;322(5906):1357-1360.
    doi:<a href="https://doi.org/10.1126/science.1164482">10.1126/science.1164482</a>
  apa: Fragner, A., Göppl, M., Fink, J. M., Baur, M., Bianchetti, R., Leek, P., …
    Wallraff, A. (2008). Resolving vacuum fluctuations in an electrical circuit by
    measuring the lamb shift. <i>Science</i>. American Association for the Advancement
    of Science. <a href="https://doi.org/10.1126/science.1164482">https://doi.org/10.1126/science.1164482</a>
  chicago: Fragner, A, M Göppl, Johannes M Fink, Matthias Baur, R Bianchetti, Peter
    Leek, Alexandre Blais, and Andreas Wallraff. “Resolving Vacuum Fluctuations in
    an Electrical Circuit by Measuring the Lamb Shift.” <i>Science</i>. American Association
    for the Advancement of Science, 2008. <a href="https://doi.org/10.1126/science.1164482">https://doi.org/10.1126/science.1164482</a>.
  ieee: A. Fragner <i>et al.</i>, “Resolving vacuum fluctuations in an electrical
    circuit by measuring the lamb shift,” <i>Science</i>, vol. 322, no. 5906. American
    Association for the Advancement of Science, pp. 1357–1360, 2008.
  ista: Fragner A, Göppl M, Fink JM, Baur M, Bianchetti R, Leek P, Blais A, Wallraff
    A. 2008. Resolving vacuum fluctuations in an electrical circuit by measuring the
    lamb shift. Science. 322(5906), 1357–1360.
  mla: Fragner, A., et al. “Resolving Vacuum Fluctuations in an Electrical Circuit
    by Measuring the Lamb Shift.” <i>Science</i>, vol. 322, no. 5906, American Association
    for the Advancement of Science, 2008, pp. 1357–60, doi:<a href="https://doi.org/10.1126/science.1164482">10.1126/science.1164482</a>.
  short: A. Fragner, M. Göppl, J.M. Fink, M. Baur, R. Bianchetti, P. Leek, A. Blais,
    A. Wallraff, Science 322 (2008) 1357–1360.
date_created: 2018-12-11T11:53:53Z
date_published: 2008-11-28T00:00:00Z
date_updated: 2021-01-12T06:53:03Z
day: '28'
doi: 10.1126/science.1164482
extern: 1
intvolume: '       322'
issue: '5906'
month: '11'
page: 1357 - 1360
publication: Science
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '5357'
quality_controlled: 0
status: public
title: Resolving vacuum fluctuations in an electrical circuit by measuring the lamb
  shift
type: journal_article
volume: 322
year: '2008'
...
---
_id: '1765'
abstract:
- lang: eng
  text: High quality on-chip microwave resonators have recently found prominent new
    applications in quantum optics and quantum information processing experiments
    with superconducting electronic circuits, a field now known as circuit quantum
    electrodynamics (QED). They are also used as single photon detectors and parametric
    amplifiers. Here we analyze the physical properties of coplanar waveguide resonators
    and their relation to the materials properties for use in circuit QED. We have
    designed and fabricated resonators with fundamental frequencies from 2 to 9 GHz
    and quality factors ranging from a few hundreds to a several hundred thousands
    controlled by appropriately designed input and output coupling capacitors. The
    microwave transmission spectra measured at temperatures of 20 mK are shown to
    be in good agreement with theoretical lumped element and distributed element transmission
    matrix models. In particular, the experimentally determined resonance frequencies,
    quality factors, and insertion losses are fully and consistently explained by
    the two models for all measured devices. The high level of control and flexibility
    in design renders these resonators ideal for storing and manipulating quantum
    electromagnetic fields in integrated superconducting electronic circuits.
acknowledgement: This work was supported by Swiss National Fund (SNF) and ETH Zürich.
  P.J.L. was supported by the EC with a MC-EIF
author:
- first_name: M
  full_name: Göppl, M
  last_name: Göppl
- first_name: A
  full_name: Fragner, A
  last_name: Fragner
- first_name: Matthias
  full_name: Baur, Matthias P
  last_name: Baur
- first_name: R
  full_name: Bianchetti, R
  last_name: Bianchetti
- first_name: Stefan
  full_name: Filipp, Stefan
  last_name: Filipp
- first_name: Johannes M
  full_name: Johannes Fink
  id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
  last_name: Fink
  orcid: 0000-0001-8112-028X
- first_name: Peter
  full_name: Leek, Peter J
  last_name: Leek
- first_name: G
  full_name: Puebla, G
  last_name: Puebla
- first_name: L.
  full_name: Steffen, L. Kraig
  last_name: Steffen
- first_name: Andreas
  full_name: Wallraff, Andreas
  last_name: Wallraff
citation:
  ama: Göppl M, Fragner A, Baur M, et al. Coplanar waveguide resonators for circuit
    quantum electrodynamics. <i>Journal of Applied Physics</i>. 2008;104(11). doi:<a
    href="https://doi.org/10.1063/1.3010859">10.1063/1.3010859</a>
  apa: Göppl, M., Fragner, A., Baur, M., Bianchetti, R., Filipp, S., Fink, J. M.,
    … Wallraff, A. (2008). Coplanar waveguide resonators for circuit quantum electrodynamics.
    <i>Journal of Applied Physics</i>. American Institute of Physics. <a href="https://doi.org/10.1063/1.3010859">https://doi.org/10.1063/1.3010859</a>
  chicago: Göppl, M, A Fragner, Matthias Baur, R Bianchetti, Stefan Filipp, Johannes
    M Fink, Peter Leek, G Puebla, L. Steffen, and Andreas Wallraff. “Coplanar Waveguide
    Resonators for Circuit Quantum Electrodynamics.” <i>Journal of Applied Physics</i>.
    American Institute of Physics, 2008. <a href="https://doi.org/10.1063/1.3010859">https://doi.org/10.1063/1.3010859</a>.
  ieee: M. Göppl <i>et al.</i>, “Coplanar waveguide resonators for circuit quantum
    electrodynamics,” <i>Journal of Applied Physics</i>, vol. 104, no. 11. American
    Institute of Physics, 2008.
  ista: Göppl M, Fragner A, Baur M, Bianchetti R, Filipp S, Fink JM, Leek P, Puebla
    G, Steffen L, Wallraff A. 2008. Coplanar waveguide resonators for circuit quantum
    electrodynamics. Journal of Applied Physics. 104(11).
  mla: Göppl, M., et al. “Coplanar Waveguide Resonators for Circuit Quantum Electrodynamics.”
    <i>Journal of Applied Physics</i>, vol. 104, no. 11, American Institute of Physics,
    2008, doi:<a href="https://doi.org/10.1063/1.3010859">10.1063/1.3010859</a>.
  short: M. Göppl, A. Fragner, M. Baur, R. Bianchetti, S. Filipp, J.M. Fink, P. Leek,
    G. Puebla, L. Steffen, A. Wallraff, Journal of Applied Physics 104 (2008).
date_created: 2018-12-11T11:53:53Z
date_published: 2008-01-01T00:00:00Z
date_updated: 2021-01-12T06:53:03Z
day: '01'
doi: 10.1063/1.3010859
extern: 1
intvolume: '       104'
issue: '11'
main_file_link:
- open_access: '1'
  url: http://arxiv.org/abs/0807.4094
month: '01'
oa: 1
publication: Journal of Applied Physics
publication_status: published
publisher: American Institute of Physics
publist_id: '5355'
quality_controlled: 0
status: public
title: Coplanar waveguide resonators for circuit quantum electrodynamics
type: journal_article
volume: 104
year: '2008'
...
---
_id: '17721'
abstract:
- lang: eng
  text: High-redshift quasars (z >~ 6) drive ionization fronts into the intergalactic
    medium (IGM). If the thickness of the front can be measured, it can provide a
    novel constraint on the ionizing spectral energy distribution (SED). Here we follow
    the propagation of an I-front into a uniform IGM, and compute its thickness for
    a range of possible quasar spectra and ages. We also explore the effects of uniform
    and non-uniform ionizing backgrounds. We find that even for hard spectra, the
    fronts are initially thin, with a thickness much smaller than the mean free path
    of ionizing photons, but the thickness increases as the front approaches equilibrium
    in 10^8 - 10^9 years, and can eventually significantly exceed simple estimates
    based on the mean free path. With a high intrinsic hydrogen column density obscuring
    the source (log(N_H/cm^-2) >~ 19.2) or a hard power-law spectrum combined with
    some obscuration (e.g. dlog(F_\nu)/dlog(\nu) >~ -1.2 at log(N_H/cm^-2) >~ 18.0),
    the thickness of the front exceeds ~1 physical Mpc and may be measurable from
    the morphology of its redshifted 21cm signal. We find that the highly ionized
    inner part of the front, which may be probed by Lyman line absorption spectra,
    remains sharp for bright quasars unless a large obscuring column (log(N_H/cm^-2)
    >~ 19.2) removes most of their ionizing photons up to ~40 eV. For obscured sources
    with log(N_H/cm^-2) >~ 19.8, embedded in a significantly neutral IGM, the black
    Lyman-alpha trough (where the neutral fraction is ~10^-3) underestimates the size
    of the HII region by a factor of >~4.
article_processing_charge: No
article_type: original
author:
- first_name: R. H.
  full_name: Kramer, R. H.
  last_name: Kramer
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
citation:
  ama: Kramer RH, Haiman Z. The thickness of high-redshift quasar ionization fronts
    as a constraint on the ionizing spectral energy distribution. <i>Monthly Notices
    of the Royal Astronomical Society</i>. 2008;385(3):1561-1575. doi:<a href="https://doi.org/10.1111/j.1365-2966.2008.12945.x">10.1111/j.1365-2966.2008.12945.x</a>
  apa: Kramer, R. H., &#38; Haiman, Z. (2008). The thickness of high-redshift quasar
    ionization fronts as a constraint on the ionizing spectral energy distribution.
    <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press.
    <a href="https://doi.org/10.1111/j.1365-2966.2008.12945.x">https://doi.org/10.1111/j.1365-2966.2008.12945.x</a>
  chicago: Kramer, R. H., and Zoltán Haiman. “The Thickness of High-Redshift Quasar
    Ionization Fronts as a Constraint on the Ionizing Spectral Energy Distribution.”
    <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press,
    2008. <a href="https://doi.org/10.1111/j.1365-2966.2008.12945.x">https://doi.org/10.1111/j.1365-2966.2008.12945.x</a>.
  ieee: R. H. Kramer and Z. Haiman, “The thickness of high-redshift quasar ionization
    fronts as a constraint on the ionizing spectral energy distribution,” <i>Monthly
    Notices of the Royal Astronomical Society</i>, vol. 385, no. 3. Oxford University
    Press, pp. 1561–1575, 2008.
  ista: Kramer RH, Haiman Z. 2008. The thickness of high-redshift quasar ionization
    fronts as a constraint on the ionizing spectral energy distribution. Monthly Notices
    of the Royal Astronomical Society. 385(3), 1561–1575.
  mla: Kramer, R. H., and Zoltán Haiman. “The Thickness of High-Redshift Quasar Ionization
    Fronts as a Constraint on the Ionizing Spectral Energy Distribution.” <i>Monthly
    Notices of the Royal Astronomical Society</i>, vol. 385, no. 3, Oxford University
    Press, 2008, pp. 1561–75, doi:<a href="https://doi.org/10.1111/j.1365-2966.2008.12945.x">10.1111/j.1365-2966.2008.12945.x</a>.
  short: R.H. Kramer, Z. Haiman, Monthly Notices of the Royal Astronomical Society
    385 (2008) 1561–1575.
date_created: 2024-09-06T09:09:01Z
date_published: 2008-03-13T00:00:00Z
date_updated: 2024-09-25T13:54:14Z
day: '13'
doi: 10.1111/j.1365-2966.2008.12945.x
extern: '1'
intvolume: '       385'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1111/j.1365-2966.2008.12945.x
month: '03'
oa: 1
oa_version: Published Version
page: 1561-1575
publication: Monthly Notices of the Royal Astronomical Society
publication_identifier:
  issn:
  - 0035-8711
  - 1365-2966
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: The thickness of high-redshift quasar ionization fronts as a constraint on
  the ionizing spectral energy distribution
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 385
year: '2008'
...
---
_id: '17734'
abstract:
- lang: eng
  text: Electromagnetic (EM) counterparts to supermassive black hole binary mergers
    observed by LISA can be localized to within the field of view of astronomical
    instruments ~10 deg^2 hours to weeks prior to coalescence. The temporal coincidence
    of any prompt EM counterpart with a gravitationally-timed merger may offer the
    best chance of identifying a unique host galaxy. We discuss the challenges posed
    by searches for prompt EM counterparts and propose novel observational strategies
    to address them. In particular, we discuss the size and shape evolution of the
    LISA localization error ellipses on the sky, and quantify the requirements for
    dedicated EM surveys of the area prior to coalescence. A triggered EM counterpart
    search campaign will require monitoring a several-square degree area. It could
    aim for variability at the 24-27 mag level in optical bands, for example, which
    corresponds to 1-10% of the Eddington luminosity of the prime LISA sources of
    10^6-10^7 Msun BHs at z=1-2, on time-scales of minutes to hours, the orbital time-scale
    of the binary in the last 2-4 weeks. A cross-correlation of the period of any
    variable EM signal with the quasi-periodic gravitational waveform over 10-1000
    cycles may aid the detection. Alternatively, EM searches can detect a transient
    signal accompanying the coalescence. We highlight the measurement of differences
    in the arrival times of photons and gravitons from the same cosmological source
    as a valuable independent test of the massive character of gravity, and of possible
    violations of Lorentz invariance in the gravity sector.
article_processing_charge: No
article_type: original
author:
- first_name: Bence
  full_name: Kocsis, Bence
  last_name: Kocsis
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
- first_name: Kristen
  full_name: Menou, Kristen
  last_name: Menou
citation:
  ama: 'Kocsis B, Haiman Z, Menou K. Premerger localization of gravitational wave
    standard sirens with LISA: Triggered search for an electromagnetic counterpart.
    <i>The Astrophysical Journal</i>. 2008;684(2):870-887. doi:<a href="https://doi.org/10.1086/590230">10.1086/590230</a>'
  apa: 'Kocsis, B., Haiman, Z., &#38; Menou, K. (2008). Premerger localization of
    gravitational wave standard sirens with LISA: Triggered search for an electromagnetic
    counterpart. <i>The Astrophysical Journal</i>. American Astronomical Society.
    <a href="https://doi.org/10.1086/590230">https://doi.org/10.1086/590230</a>'
  chicago: 'Kocsis, Bence, Zoltán Haiman, and Kristen Menou. “Premerger Localization
    of Gravitational Wave Standard Sirens with LISA: Triggered Search for an Electromagnetic
    Counterpart.” <i>The Astrophysical Journal</i>. American Astronomical Society,
    2008. <a href="https://doi.org/10.1086/590230">https://doi.org/10.1086/590230</a>.'
  ieee: 'B. Kocsis, Z. Haiman, and K. Menou, “Premerger localization of gravitational
    wave standard sirens with LISA: Triggered search for an electromagnetic counterpart,”
    <i>The Astrophysical Journal</i>, vol. 684, no. 2. American Astronomical Society,
    pp. 870–887, 2008.'
  ista: 'Kocsis B, Haiman Z, Menou K. 2008. Premerger localization of gravitational
    wave standard sirens with LISA: Triggered search for an electromagnetic counterpart.
    The Astrophysical Journal. 684(2), 870–887.'
  mla: 'Kocsis, Bence, et al. “Premerger Localization of Gravitational Wave Standard
    Sirens with LISA: Triggered Search for an Electromagnetic Counterpart.” <i>The
    Astrophysical Journal</i>, vol. 684, no. 2, American Astronomical Society, 2008,
    pp. 870–87, doi:<a href="https://doi.org/10.1086/590230">10.1086/590230</a>.'
  short: B. Kocsis, Z. Haiman, K. Menou, The Astrophysical Journal 684 (2008) 870–887.
date_created: 2024-09-06T09:18:47Z
date_published: 2008-09-10T00:00:00Z
date_updated: 2024-09-26T07:56:49Z
day: '10'
doi: 10.1086/590230
extern: '1'
intvolume: '       684'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1086/590230
month: '09'
oa: 1
oa_version: Published Version
page: 870-887
publication: The Astrophysical Journal
publication_identifier:
  issn:
  - 0004-637X
  - 1538-4357
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Premerger localization of gravitational wave standard sirens with LISA: Triggered
  search for an electromagnetic counterpart'
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 684
year: '2008'
...
---
_id: '17751'
abstract:
- lang: eng
  text: With the help of numerical simulations, we examine two aspects of feedback
    from the first generation of stars on later star formation. First, we investigate
    the impact of relic HII regions on forming halos. We find that the positive and
    negative effects of such feedback nearly cancel because the increase in entropy
    due to heating is balanced by the increase in the H 2 fraction due to the free
    electrons. However, these halos can be delayed more easily by a background Lyman-Werner
    flux. Second, we show that HD cooling is important in halos which have been ionized
    and allowed to recombine. Gas is allowed to cool to the CMB temperature at densities
    around n∼10 4cm-3, reducing the accreted mass by a factor of a few. However, as
    the collapse proceeds, the central gas density exceeds the critical density of
    HD and heats until HD cooling is no longer important. Therefore the behaviour
    of the (smaller mass) core is relatively unaffected by HD cooling.
article_processing_charge: No
author:
- first_name: Greg L.
  full_name: Bryan, Greg L.
  last_name: Bryan
- first_name: Ian D.
  full_name: McGreer, Ian D.
  last_name: McGreer
- first_name: Andrei
  full_name: Mesinger, Andrei
  last_name: Mesinger
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
citation:
  ama: 'Bryan GL, McGreer ID, Mesinger A, Haiman Z. Feedback effects on population
    III star formation. In: <i>AIP Conference Proceedings</i>. American Institute
    of Physics; 2008. doi:<a href="https://doi.org/10.1063/1.2905582">10.1063/1.2905582</a>'
  apa: 'Bryan, G. L., McGreer, I. D., Mesinger, A., &#38; Haiman, Z. (2008). Feedback
    effects on population III star formation. In <i>AIP Conference Proceedings</i>.
    Santa Fe, NM, United States: American Institute of Physics. <a href="https://doi.org/10.1063/1.2905582">https://doi.org/10.1063/1.2905582</a>'
  chicago: Bryan, Greg L., Ian D. McGreer, Andrei Mesinger, and Zoltán Haiman. “Feedback
    Effects on Population III Star Formation.” In <i>AIP Conference Proceedings</i>.
    American Institute of Physics, 2008. <a href="https://doi.org/10.1063/1.2905582">https://doi.org/10.1063/1.2905582</a>.
  ieee: G. L. Bryan, I. D. McGreer, A. Mesinger, and Z. Haiman, “Feedback effects
    on population III star formation,” in <i>AIP Conference Proceedings</i>, Santa
    Fe, NM, United States, 2008.
  ista: 'Bryan GL, McGreer ID, Mesinger A, Haiman Z. 2008. Feedback effects on population
    III star formation. AIP Conference Proceedings. FIRST STARS III: First Stars II
    Conference.'
  mla: Bryan, Greg L., et al. “Feedback Effects on Population III Star Formation.”
    <i>AIP Conference Proceedings</i>, American Institute of Physics, 2008, doi:<a
    href="https://doi.org/10.1063/1.2905582">10.1063/1.2905582</a>.
  short: G.L. Bryan, I.D. McGreer, A. Mesinger, Z. Haiman, in:, AIP Conference Proceedings,
    American Institute of Physics, 2008.
conference:
  end_date: 2007-07-20
  location: Santa Fe, NM, United States
  name: 'FIRST STARS III: First Stars II Conference'
  start_date: 2007-07-15
date_created: 2024-09-06T09:39:10Z
date_published: 2008-03-11T00:00:00Z
date_updated: 2024-09-30T07:46:06Z
day: '11'
doi: 10.1063/1.2905582
extern: '1'
language:
- iso: eng
main_file_link:
- url: https://doi.org/10.1063/1.2905582
month: '03'
oa_version: None
publication: AIP Conference Proceedings
publication_identifier:
  issn:
  - 0094-243X
publication_status: published
publisher: American Institute of Physics
quality_controlled: '1'
scopus_import: '1'
status: public
title: Feedback effects on population III star formation
type: conference
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
year: '2008'
...
---
_id: '17752'
abstract:
- lang: eng
  text: Supermassive black hole binaries (BHBs) produced in galaxy mergers recoil
    at the time of their coalescence due to the emission of gravitational waves (GWs).
    We simulate the response of a thin, 2D disk of collisionless particles, initially
    on circular orbits around a 10^6 M_sun BHB, to kicks that are either parallel
    or perpendicular to the initial orbital plane. Typical kick velocities (v_k) can
    exceed the sound speed in a circumbinary gas disk. While the inner disk is strongly
    bound to the recoiling binary, the outer disk is only weakly bound or unbound.
    This leads to differential motions in the disturbed disk that increase with radius
    and can become supersonic at ~700 Schwarzschild radii for v_k ~500 km/s, implying
    that shocks form beyond this radius. We indeed find that kicks in the disk plane
    lead to immediate strong density enhancements (within weeks) in a tightly wound
    spiral caustic, propagating outward at the speed v_k. Concentric density enhancements
    are also observed for kicks perpendicular to the disk, but are weaker and develop
    into caustics only after a long delay (>1 year). Unless both BH spins are low
    or precisely aligned with the orbital angular momentum, a significant fraction
    (> several %) of kicks are sufficiently large and well aligned with the orbital
    plane for strong shocks to be produced. The shocks could result in an afterglow
    whose characteristic photon energy increases with time, from the UV (~10eV) to
    the soft X-ray (~100eV) range, between one month and one year after the merger.
    This could help identify EM counterparts to GW sources discovered by LISA.
article_processing_charge: No
article_type: original
author:
- first_name: Zoltán
  full_name: Lippai, Zoltán
  last_name: Lippai
- first_name: Zsolt
  full_name: Frei, Zsolt
  last_name: Frei
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
citation:
  ama: Lippai Z, Frei Z, Haiman Z. Prompt shocks in the gas disk around a recoiling
    supermassive black hole binary. <i>The Astrophysical Journal</i>. 2008;676(1):L5-L8.
    doi:<a href="https://doi.org/10.1086/587034">10.1086/587034</a>
  apa: Lippai, Z., Frei, Z., &#38; Haiman, Z. (2008). Prompt shocks in the gas disk
    around a recoiling supermassive black hole binary. <i>The Astrophysical Journal</i>.
    American Astronomical Society. <a href="https://doi.org/10.1086/587034">https://doi.org/10.1086/587034</a>
  chicago: Lippai, Zoltán, Zsolt Frei, and Zoltán Haiman. “Prompt Shocks in the Gas
    Disk around a Recoiling Supermassive Black Hole Binary.” <i>The Astrophysical
    Journal</i>. American Astronomical Society, 2008. <a href="https://doi.org/10.1086/587034">https://doi.org/10.1086/587034</a>.
  ieee: Z. Lippai, Z. Frei, and Z. Haiman, “Prompt shocks in the gas disk around a
    recoiling supermassive black hole binary,” <i>The Astrophysical Journal</i>, vol.
    676, no. 1. American Astronomical Society, pp. L5–L8, 2008.
  ista: Lippai Z, Frei Z, Haiman Z. 2008. Prompt shocks in the gas disk around a recoiling
    supermassive black hole binary. The Astrophysical Journal. 676(1), L5–L8.
  mla: Lippai, Zoltán, et al. “Prompt Shocks in the Gas Disk around a Recoiling Supermassive
    Black Hole Binary.” <i>The Astrophysical Journal</i>, vol. 676, no. 1, American
    Astronomical Society, 2008, pp. L5–8, doi:<a href="https://doi.org/10.1086/587034">10.1086/587034</a>.
  short: Z. Lippai, Z. Frei, Z. Haiman, The Astrophysical Journal 676 (2008) L5–L8.
date_created: 2024-09-06T09:40:05Z
date_published: 2008-03-20T00:00:00Z
date_updated: 2024-09-30T07:50:45Z
day: '20'
doi: 10.1086/587034
extern: '1'
intvolume: '       676'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1086/587034
month: '03'
oa: 1
oa_version: Published Version
page: L5-L8
publication: The Astrophysical Journal
publication_identifier:
  issn:
  - 0004-637X
  - 1538-4357
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Prompt shocks in the gas disk around a recoiling supermassive black hole binary
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 676
year: '2008'
...
---
_id: '17756'
abstract:
- lang: eng
  text: At the epoch of reionization, when the high-redshift inter-galactic medium
    (IGM) is being enriched with metals, the 63.2 micron fine structure line of OI
    is pumped by the ~ 1300 AA soft UV background and introduces a spectral distortion
    in the Cosmic Microwave Background (CMB). Here we use a toy model for the spatial
    distribution of neutral oxygen, assuming metal bubbles surround dark matter halos,
    and compute the fluctuations of this distortion, and the angular power spectrum
    it imprints on the CMB. We discuss the dependence of the power spectrum on the
    velocity of the winds polluting the IGM with metals, the minimum mass of the halos
    producing these winds, and on the cosmic epoch when the OI pumping occurs. We
    find that, although the clustering signal of the CMB distortion is weak \delta
    y_{rms} ~ 10^{-7} (roughly corresponding to a temperature anisotropy of few nK),
    it may be reachable in deep integrations with high-sensitivity infrared detectors.
    Even without a detection, these instruments should be able to useful constraints
    on the heavy element enrichment history of the IGM.
article_processing_charge: No
article_type: original
author:
- first_name: Carlos
  full_name: Hernandez‐Monteagudo, Carlos
  last_name: Hernandez‐Monteagudo
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
- first_name: Licia
  full_name: Verde, Licia
  last_name: Verde
- first_name: Raul
  full_name: Jimenez, Raul
  last_name: Jimenez
citation:
  ama: Hernandez‐Monteagudo C, Haiman Z, Verde L, Jimenez R. Oxygen pumping. II. Probing
    the inhomogeneous metal enrichment at the epoch of reionization with high‐frequency
    CMB observations. <i>The Astrophysical Journal</i>. 2008;672(1):33-39. doi:<a
    href="https://doi.org/10.1086/523872">10.1086/523872</a>
  apa: Hernandez‐Monteagudo, C., Haiman, Z., Verde, L., &#38; Jimenez, R. (2008).
    Oxygen pumping. II. Probing the inhomogeneous metal enrichment at the epoch of
    reionization with high‐frequency CMB observations. <i>The Astrophysical Journal</i>.
    American Astronomical Society. <a href="https://doi.org/10.1086/523872">https://doi.org/10.1086/523872</a>
  chicago: Hernandez‐Monteagudo, Carlos, Zoltán Haiman, Licia Verde, and Raul Jimenez.
    “Oxygen Pumping. II. Probing the Inhomogeneous Metal Enrichment at the Epoch of
    Reionization with High‐frequency CMB Observations.” <i>The Astrophysical Journal</i>.
    American Astronomical Society, 2008. <a href="https://doi.org/10.1086/523872">https://doi.org/10.1086/523872</a>.
  ieee: C. Hernandez‐Monteagudo, Z. Haiman, L. Verde, and R. Jimenez, “Oxygen pumping.
    II. Probing the inhomogeneous metal enrichment at the epoch of reionization with
    high‐frequency CMB observations,” <i>The Astrophysical Journal</i>, vol. 672,
    no. 1. American Astronomical Society, pp. 33–39, 2008.
  ista: Hernandez‐Monteagudo C, Haiman Z, Verde L, Jimenez R. 2008. Oxygen pumping.
    II. Probing the inhomogeneous metal enrichment at the epoch of reionization with
    high‐frequency CMB observations. The Astrophysical Journal. 672(1), 33–39.
  mla: Hernandez‐Monteagudo, Carlos, et al. “Oxygen Pumping. II. Probing the Inhomogeneous
    Metal Enrichment at the Epoch of Reionization with High‐frequency CMB Observations.”
    <i>The Astrophysical Journal</i>, vol. 672, no. 1, American Astronomical Society,
    2008, pp. 33–39, doi:<a href="https://doi.org/10.1086/523872">10.1086/523872</a>.
  short: C. Hernandez‐Monteagudo, Z. Haiman, L. Verde, R. Jimenez, The Astrophysical
    Journal 672 (2008) 33–39.
date_created: 2024-09-06T09:44:50Z
date_published: 2008-01-01T00:00:00Z
date_updated: 2024-09-30T08:39:17Z
day: '01'
doi: 10.1086/523872
extern: '1'
intvolume: '       672'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1086/523872
month: '01'
oa: 1
oa_version: Published Version
page: 33-39
publication: The Astrophysical Journal
publication_identifier:
  issn:
  - 0004-637X
  - 1538-4357
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Oxygen pumping. II. Probing the inhomogeneous metal enrichment at the epoch
  of reionization with high‐frequency CMB observations
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 672
year: '2008'
...
---
_id: '17762'
abstract:
- lang: eng
  text: "We conduct a Markov Chain Monte Carlo study of the Dvali-Gabadadze-Porrati
    self-accelerating braneworld scenario given the cosmic microwave background (CMB)
    anisotropy, supernovae and Hubble constant data by implementing an effective dark
    energy prescription for modified gravity into a standard Einstein-Boltzmann code.
    We find no way to alleviate the tension between distance measures and horizon-scale
    growth in this model. Growth alterations due to perturbations propagating into
    the bulk appear as excess CMB anisotropy at the lowest multipoles. In a flat cosmology,
    the maximum likelihood Dvali-Gabadadze-Porrati model is nominally a 5.3⁢\U0001D70E
    poorer fit than \U0001D6EC⁢CDM. Curvature can reduce the tension between distance
    measures but only at the expense of exacerbating the problem with growth leading
    to a 4.8⁢\U0001D70E result that is dominated by the low multipole CMB temperature
    spectrum. While changing the initial conditions to reduce large-scale power can
    flatten the temperature spectrum, this also suppresses the large angle polarization
    spectrum in violation of recent results from the five-year Wilkinson Microwave
    Anisotropy Probe. The failure of this model highlights the power of combining
    growth and distance measures in cosmology as a test of gravity on the largest
    scales."
article_number: '103509'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Wenjuan
  full_name: Fang, Wenjuan
  last_name: Fang
- first_name: Sheng
  full_name: Wang, Sheng
  last_name: Wang
- first_name: Wayne
  full_name: Hu, Wayne
  last_name: Hu
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
- first_name: Lam
  full_name: Hui, Lam
  last_name: Hui
- first_name: Morgan
  full_name: May, Morgan
  last_name: May
citation:
  ama: Fang W, Wang S, Hu W, Haiman Z, Hui L, May M. Challenges to the DGP model from
    horizon-scale growth and geometry. <i>Physical Review D</i>. 2008;78(10). doi:<a
    href="https://doi.org/10.1103/physrevd.78.103509">10.1103/physrevd.78.103509</a>
  apa: Fang, W., Wang, S., Hu, W., Haiman, Z., Hui, L., &#38; May, M. (2008). Challenges
    to the DGP model from horizon-scale growth and geometry. <i>Physical Review D</i>.
    American Physical Society. <a href="https://doi.org/10.1103/physrevd.78.103509">https://doi.org/10.1103/physrevd.78.103509</a>
  chicago: Fang, Wenjuan, Sheng Wang, Wayne Hu, Zoltán Haiman, Lam Hui, and Morgan
    May. “Challenges to the DGP Model from Horizon-Scale Growth and Geometry.” <i>Physical
    Review D</i>. American Physical Society, 2008. <a href="https://doi.org/10.1103/physrevd.78.103509">https://doi.org/10.1103/physrevd.78.103509</a>.
  ieee: W. Fang, S. Wang, W. Hu, Z. Haiman, L. Hui, and M. May, “Challenges to the
    DGP model from horizon-scale growth and geometry,” <i>Physical Review D</i>, vol.
    78, no. 10. American Physical Society, 2008.
  ista: Fang W, Wang S, Hu W, Haiman Z, Hui L, May M. 2008. Challenges to the DGP
    model from horizon-scale growth and geometry. Physical Review D. 78(10), 103509.
  mla: Fang, Wenjuan, et al. “Challenges to the DGP Model from Horizon-Scale Growth
    and Geometry.” <i>Physical Review D</i>, vol. 78, no. 10, 103509, American Physical
    Society, 2008, doi:<a href="https://doi.org/10.1103/physrevd.78.103509">10.1103/physrevd.78.103509</a>.
  short: W. Fang, S. Wang, W. Hu, Z. Haiman, L. Hui, M. May, Physical Review D 78
    (2008).
date_created: 2024-09-06T09:49:53Z
date_published: 2008-11-10T00:00:00Z
date_updated: 2024-09-30T09:16:05Z
day: '10'
doi: 10.1103/physrevd.78.103509
extern: '1'
external_id:
  arxiv:
  - '0808.2208'
intvolume: '        78'
issue: '10'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: ' https://doi.org/10.48550/arXiv.0808.2208'
month: '11'
oa: 1
oa_version: Preprint
publication: Physical Review D
publication_identifier:
  issn:
  - 1550-7998
  - 1550-2368
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Challenges to the DGP model from horizon-scale growth and geometry
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 78
year: '2008'
...
---
_id: '17773'
abstract:
- lang: eng
  text: The notion that microparsec-scale black holes can be used to probe gigaparsec-scale
    physics may seem counterintuitive, at first. Yet, the gravitational observatory
    LISA will detect cosmologically-distant coalescing pairs of massive black holes,
    accurately measure their luminosity distance and help identify an electromagnetic
    counterpart or a host galaxy. A wide variety of new black hole studies and a gravitational
    version of Hubble’s diagram become possible, if host galaxies are successfully
    identified. Furthermore, if dark energy is a manifestation of large-scale modified
    gravity, deviations from general relativistic expectations could become apparent
    in a gravitational signal propagated over cosmological scales, especially when
    compared to the electromagnetic signal from a same source. Finally, since inspirals
    of white dwarfs into massive black holes at cosmological distances may permit
    pre-merger localizations, we suggest that careful monitoring of these events and
    any associated electromagnetic counterpart could lead to high-precision cosmological
    measurements with LISA.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Kristen
  full_name: Menou, Kristen
  last_name: Menou
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
- first_name: Bence
  full_name: Kocsis, Bence
  last_name: Kocsis
citation:
  ama: Menou K, Haiman Z, Kocsis B. Cosmological physics with black holes (and possibly
    white dwarfs). <i>New Astronomy Reviews</i>. 2008;51(10-12):884-890. doi:<a href="https://doi.org/10.1016/j.newar.2008.03.020">10.1016/j.newar.2008.03.020</a>
  apa: Menou, K., Haiman, Z., &#38; Kocsis, B. (2008). Cosmological physics with black
    holes (and possibly white dwarfs). <i>New Astronomy Reviews</i>. Elsevier BV.
    <a href="https://doi.org/10.1016/j.newar.2008.03.020">https://doi.org/10.1016/j.newar.2008.03.020</a>
  chicago: Menou, Kristen, Zoltán Haiman, and Bence Kocsis. “Cosmological Physics
    with Black Holes (and Possibly White Dwarfs).” <i>New Astronomy Reviews</i>. Elsevier
    BV, 2008. <a href="https://doi.org/10.1016/j.newar.2008.03.020">https://doi.org/10.1016/j.newar.2008.03.020</a>.
  ieee: K. Menou, Z. Haiman, and B. Kocsis, “Cosmological physics with black holes
    (and possibly white dwarfs),” <i>New Astronomy Reviews</i>, vol. 51, no. 10–12.
    Elsevier BV, pp. 884–890, 2008.
  ista: Menou K, Haiman Z, Kocsis B. 2008. Cosmological physics with black holes (and
    possibly white dwarfs). New Astronomy Reviews. 51(10–12), 884–890.
  mla: Menou, Kristen, et al. “Cosmological Physics with Black Holes (and Possibly
    White Dwarfs).” <i>New Astronomy Reviews</i>, vol. 51, no. 10–12, Elsevier BV,
    2008, pp. 884–90, doi:<a href="https://doi.org/10.1016/j.newar.2008.03.020">10.1016/j.newar.2008.03.020</a>.
  short: K. Menou, Z. Haiman, B. Kocsis, New Astronomy Reviews 51 (2008) 884–890.
date_created: 2024-09-06T10:02:53Z
date_published: 2008-05-01T00:00:00Z
date_updated: 2024-09-30T11:28:25Z
day: '01'
doi: 10.1016/j.newar.2008.03.020
extern: '1'
external_id:
  arxiv:
  - '0803.3627'
intvolume: '        51'
issue: 10-12
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: ' https://doi.org/10.48550/arXiv.0803.3627'
month: '05'
oa: 1
oa_version: Preprint
page: 884-890
publication: New Astronomy Reviews
publication_identifier:
  issn:
  - 1387-6473
publication_status: published
publisher: Elsevier BV
quality_controlled: '1'
scopus_import: '1'
status: public
title: Cosmological physics with black holes (and possibly white dwarfs)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 51
year: '2008'
...
---
_id: '17778'
abstract:
- lang: eng
  text: The earliest generation of stars and black holes must have established an
    early ‘Lyman–Werner’ background (LWB) at high redshift, prior to the epoch of
    reionization. Because of the long mean free path of photons with energies hν <
    13.6 eV, the LWB was nearly uniform. However, some variation in the LWB is expected
    due to the discrete nature of the sources, and their highly clustered spatial
    distribution. In this paper, we compute the probability distribution function
    (PDF) of the LW flux that irradiates dark matter (DM) haloes collapsing at high
    redshift (z≈ 10). Our model accounts for (i) the clustering of DM haloes, (ii)
    Poisson fluctuations in the number of corresponding star-forming galaxies and
    (iii) scatter in the LW luminosity produced by haloes of a given mass (calibrated
    using local observations). We find that >99 per cent of the DM haloes are illuminated
    by an LW flux within a factor of 2 of the global mean value. However, a small
    fraction, ∼10^−8 to 10^−6, of DM haloes with virial temperatures Tvir≳ 10^4 K
    have a close luminous neighbour within ≲10 kpc, and are exposed to an LW flux
    exceeding the global mean by a factor of >20, or to J21,LW > 10^3 (in units of
    10^−21 erg s^−1 Hz^−1 sr^−1 cm^−2). This large LW flux can photodissociate H2
    molecules in the gas collapsing due to atomic cooling in these haloes, and prevent
    its further cooling and fragmentation. Such close halo pairs therefore provide
    possible sites in which primordial gas clouds collapse directly into massive black
    holes (MBH≈ 10^4−6M⊙), and subsequently grow into supermassive (MBH≳ 10^9M⊙) black
    holes by z≈ 6.
article_processing_charge: No
article_type: original
author:
- first_name: Mark
  full_name: Dijkstra, Mark
  last_name: Dijkstra
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
- first_name: Andrei
  full_name: Mesinger, Andrei
  last_name: Mesinger
- first_name: J. Stuart B.
  full_name: Wyithe, J. Stuart B.
  last_name: Wyithe
citation:
  ama: 'Dijkstra M, Haiman Z, Mesinger A, Wyithe JSB. Fluctuations in the high-redshift
    Lyman-Werner background: Close halo pairs as the origin of supermassive black
    holes. <i>Monthly Notices of the Royal Astronomical Society</i>. 2008;391(4):1961-1972.
    doi:<a href="https://doi.org/10.1111/j.1365-2966.2008.14031.x">10.1111/j.1365-2966.2008.14031.x</a>'
  apa: 'Dijkstra, M., Haiman, Z., Mesinger, A., &#38; Wyithe, J. S. B. (2008). Fluctuations
    in the high-redshift Lyman-Werner background: Close halo pairs as the origin of
    supermassive black holes. <i>Monthly Notices of the Royal Astronomical Society</i>.
    Oxford University Press. <a href="https://doi.org/10.1111/j.1365-2966.2008.14031.x">https://doi.org/10.1111/j.1365-2966.2008.14031.x</a>'
  chicago: 'Dijkstra, Mark, Zoltán Haiman, Andrei Mesinger, and J. Stuart B. Wyithe.
    “Fluctuations in the High-Redshift Lyman-Werner Background: Close Halo Pairs as
    the Origin of Supermassive Black Holes.” <i>Monthly Notices of the Royal Astronomical
    Society</i>. Oxford University Press, 2008. <a href="https://doi.org/10.1111/j.1365-2966.2008.14031.x">https://doi.org/10.1111/j.1365-2966.2008.14031.x</a>.'
  ieee: 'M. Dijkstra, Z. Haiman, A. Mesinger, and J. S. B. Wyithe, “Fluctuations in
    the high-redshift Lyman-Werner background: Close halo pairs as the origin of supermassive
    black holes,” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 391,
    no. 4. Oxford University Press, pp. 1961–1972, 2008.'
  ista: 'Dijkstra M, Haiman Z, Mesinger A, Wyithe JSB. 2008. Fluctuations in the high-redshift
    Lyman-Werner background: Close halo pairs as the origin of supermassive black
    holes. Monthly Notices of the Royal Astronomical Society. 391(4), 1961–1972.'
  mla: 'Dijkstra, Mark, et al. “Fluctuations in the High-Redshift Lyman-Werner Background:
    Close Halo Pairs as the Origin of Supermassive Black Holes.” <i>Monthly Notices
    of the Royal Astronomical Society</i>, vol. 391, no. 4, Oxford University Press,
    2008, pp. 1961–72, doi:<a href="https://doi.org/10.1111/j.1365-2966.2008.14031.x">10.1111/j.1365-2966.2008.14031.x</a>.'
  short: M. Dijkstra, Z. Haiman, A. Mesinger, J.S.B. Wyithe, Monthly Notices of the
    Royal Astronomical Society 391 (2008) 1961–1972.
date_created: 2024-09-06T10:13:39Z
date_published: 2008-12-11T00:00:00Z
date_updated: 2024-09-30T11:57:59Z
day: '11'
doi: 10.1111/j.1365-2966.2008.14031.x
extern: '1'
intvolume: '       391'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1111/j.1365-2966.2008.14031.x
month: '12'
oa: 1
oa_version: Published Version
page: 1961-1972
publication: Monthly Notices of the Royal Astronomical Society
publication_identifier:
  issn:
  - 0035-8711
  - 1365-2966
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Fluctuations in the high-redshift Lyman-Werner background: Close halo pairs
  as the origin of supermassive black holes'
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 391
year: '2008'
...
---
_id: '17787'
abstract:
- lang: eng
  text: One of the most dramatic signatures of the reionization era may be the enormous
    ionized bubbles around luminous quasars (with radii reaching ~40 comoving Mpc),
    which may survive as "fossil" ionized regions long after their source shuts off.
    Here we study how the inhomogeneous intergalactic medium (IGM) evolves inside
    such fossils. The average recombination rate declines rapidly with time, and the
    brief quasar episode significantly increases the mean free path inside the fossil
    bubbles. As a result, even a weak ionizing background generated by galaxies inside
    the fossil can maintain it in a relatively highly and uniformly ionized state.
    For example, galaxies that would ionize 20%-30% of hydrogen in a random patch
    of the IGM can maintain 80%-90% ionization inside the fossil for a duration much
    longer than the average recombination time in the IGM. Quasar fossils at z≲ 10
    thus retain their identity for nearly a Hubble time and appear "gray," distinct
    from both the average IGM (which has a "Swiss cheese" ionization topology and
    a lower mean ionized fraction) and the fully ionized bubbles around active quasars.
    More distant fossils, at z≳ 10, have a weaker galaxy-generated ionizing background
    and a higher gas density, so they can attain a Swiss cheese topology similar to
    the rest of the IGM, but with a smaller contrast between the ionized bubbles and
    the partially neutral regions separating them. Analogous He III fossils should
    exist around the epoch of He II/He III reionization at z ∼ 3, although rapid recombination
    inside the He III fossils is more common. Our model of inhomogeneous recombination
    also applies to "double-reionization" models and shows that a nonmonotonic reionization
    history is even more unlikely than previously thought.
article_processing_charge: No
article_type: original
author:
- first_name: Steven R.
  full_name: Furlanetto, Steven R.
  last_name: Furlanetto
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
- first_name: S. Peng
  full_name: Oh, S. Peng
  last_name: Oh
citation:
  ama: Furlanetto SR, Haiman Z, Oh SP. Fossil Ionized bubbles around dead quasars
    during reionization. <i>The Astrophysical Journal</i>. 2008;686(1):25-40. doi:<a
    href="https://doi.org/10.1086/591047">10.1086/591047</a>
  apa: Furlanetto, S. R., Haiman, Z., &#38; Oh, S. P. (2008). Fossil Ionized bubbles
    around dead quasars during reionization. <i>The Astrophysical Journal</i>. American
    Astronomical Society. <a href="https://doi.org/10.1086/591047">https://doi.org/10.1086/591047</a>
  chicago: Furlanetto, Steven R., Zoltán Haiman, and S. Peng Oh. “Fossil Ionized Bubbles
    around Dead Quasars during Reionization.” <i>The Astrophysical Journal</i>. American
    Astronomical Society, 2008. <a href="https://doi.org/10.1086/591047">https://doi.org/10.1086/591047</a>.
  ieee: S. R. Furlanetto, Z. Haiman, and S. P. Oh, “Fossil Ionized bubbles around
    dead quasars during reionization,” <i>The Astrophysical Journal</i>, vol. 686,
    no. 1. American Astronomical Society, pp. 25–40, 2008.
  ista: Furlanetto SR, Haiman Z, Oh SP. 2008. Fossil Ionized bubbles around dead quasars
    during reionization. The Astrophysical Journal. 686(1), 25–40.
  mla: Furlanetto, Steven R., et al. “Fossil Ionized Bubbles around Dead Quasars during
    Reionization.” <i>The Astrophysical Journal</i>, vol. 686, no. 1, American Astronomical
    Society, 2008, pp. 25–40, doi:<a href="https://doi.org/10.1086/591047">10.1086/591047</a>.
  short: S.R. Furlanetto, Z. Haiman, S.P. Oh, The Astrophysical Journal 686 (2008)
    25–40.
date_created: 2024-09-06T10:19:49Z
date_published: 2008-10-10T00:00:00Z
date_updated: 2024-09-30T13:04:56Z
day: '10'
doi: 10.1086/591047
extern: '1'
intvolume: '       686'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1086/591047
month: '10'
oa: 1
oa_version: Preprint
page: 25-40
publication: The Astrophysical Journal
publication_identifier:
  issn:
  - 0004-637X
  - 1538-4357
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Fossil Ionized bubbles around dead quasars during reionization
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 686
year: '2008'
...
---
_id: '17788'
abstract:
- lang: eng
  text: Nongravitational processes, such as feedback from galaxies and their active
    nuclei, are believed to have injected excess entropy into the intracluster gas,
    and therefore to have modified the density profiles in galaxy clusters during
    their formation. Here we study a simple model for this so-called preheating scenario,
    and ask (1) whether it can simultaneously explain both global X-ray scaling relations
    and number counts of galaxy clusters, and (2) whether the amount of entropy required
    evolves with redshift. We adopt a baseline entropy profile that fits recent hydrodynamic
    simulations, modify the hydrostatic equilibrium condition for the gas by including
    ≈20% nonthermal pressure support, and add an entropy floor K0 that is allowed
    to vary with redshift. We find that the observed luminosity-temperature (L − T)
    relations of low-redshift (⟨ z⟩ = 0.05) HIFLUGCS clusters and high-redshift (⟨
    z⟩ = 0.80) WARPS clusters are best simultaneously reproduced with an entropy floor
    that evolves from ≈200 h^−1/3 keV cm^ 2 at z ≈ 0.8 to ≳300 h^−1/3 keV cm^ 2 at
    z < 0.05. This evolution may take place predominantly at low redshift (z≲ 0.2).
    If we restrict our analysis to the subset of bright (kT≳ 3 keV) clusters, we find
    that the evolving entropy floor can mimic a self-similar evolution in the L −
    T scaling relation. This degeneracy with self-similar evolution is, however, lifted
    when 0.5 keV ≲ kT≲ 3 keV clusters are included. Using the cosmological parameters
    from the WMAP 3 yr data, but treating σ8 as a free parameter, our model can reproduce
    the number counts of the X-ray galaxy clusters in the 158 deg2 ROSAT PSPC survey,
    with a best-fit value of σ8 = 0.80 ± 0.05.
article_processing_charge: No
article_type: original
author:
- first_name: Wenjuan
  full_name: Fang, Wenjuan
  last_name: Fang
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
citation:
  ama: Fang W, Haiman Z. An evolving entropy floor in the intracluster gas? <i>The
    Astrophysical Journal</i>. 2008;680(1):200-213. doi:<a href="https://doi.org/10.1086/587780">10.1086/587780</a>
  apa: Fang, W., &#38; Haiman, Z. (2008). An evolving entropy floor in the intracluster
    gas? <i>The Astrophysical Journal</i>. American Astronomical Society. <a href="https://doi.org/10.1086/587780">https://doi.org/10.1086/587780</a>
  chicago: Fang, Wenjuan, and Zoltán Haiman. “An Evolving Entropy Floor in the Intracluster
    Gas?” <i>The Astrophysical Journal</i>. American Astronomical Society, 2008. <a
    href="https://doi.org/10.1086/587780">https://doi.org/10.1086/587780</a>.
  ieee: W. Fang and Z. Haiman, “An evolving entropy floor in the intracluster gas?,”
    <i>The Astrophysical Journal</i>, vol. 680, no. 1. American Astronomical Society,
    pp. 200–213, 2008.
  ista: Fang W, Haiman Z. 2008. An evolving entropy floor in the intracluster gas?
    The Astrophysical Journal. 680(1), 200–213.
  mla: Fang, Wenjuan, and Zoltán Haiman. “An Evolving Entropy Floor in the Intracluster
    Gas?” <i>The Astrophysical Journal</i>, vol. 680, no. 1, American Astronomical
    Society, 2008, pp. 200–13, doi:<a href="https://doi.org/10.1086/587780">10.1086/587780</a>.
  short: W. Fang, Z. Haiman, The Astrophysical Journal 680 (2008) 200–213.
date_created: 2024-09-06T10:20:50Z
date_published: 2008-06-10T00:00:00Z
date_updated: 2024-09-30T13:33:11Z
day: '10'
doi: 10.1086/587780
extern: '1'
intvolume: '       680'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1086/587780
month: '06'
oa: 1
oa_version: Published Version
page: 200-213
publication: The Astrophysical Journal
publication_identifier:
  issn:
  - 0004-637X
  - 1538-4357
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: An evolving entropy floor in the intracluster gas?
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 680
year: '2008'
...
---
_id: '17789'
abstract:
- lang: eng
  text: Light-travel time delays distort the apparent shapes of H II regions surrounding
    bright quasars during early stages of cosmic reionization. Individual H II regions
    may remain undetectable in forthcoming redshifted 21 cm experiments. However,
    the systematic deformation along the line of sight may be detectable statistically,
    either by stacking tomographic 21 cm images of quasars identified, for example,
    by the James Webb Space Telescope, or as small-scale anisotropy in the three-dimensional
    21 cm power spectrum. Here we consider the detectability of this effect. The anisotropy
    is largest when H II regions are large and expand rapidly, and we find that if
    bright quasars contributed to the early stages of reionization, then they can
    produce significant anisotropy, on scales comparable to the typical sizes of H
    II regions of the bright quasars (≲30 Mpc). The effect therefore cannot be ignored
    when analyzing future 21 cm power spectra on small scales. If 10% of the volume
    of the intergalactic medium at z≃ 10 is ionized by quasars with typical ionizing
    luminosity of S≳ 5 × 10^56 s^−1, the distortions cause an ≳10 percent enhancement
    of the 21 cm power spectrum in the radial (redshift) direction, relative to the
    transverse directions. The level of this anisotropy exceeds that due to redshift-space
    distortion and has the opposite sign. We show that ongoing experiments such as
    Murchison Widefield Array (MWA, formerly known as the Mileura Widefield Array)
    should be able to detect this effect. A detection would reveal the presence of
    bright quasars and shed light on the ionizing yield and age of the ionizing sources
    and the distribution and small-scale clumping of neutral intergalactic gas in
    their vicinity.
article_processing_charge: No
article_type: original
author:
- first_name: Shiv
  full_name: Sethi, Shiv
  last_name: Sethi
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
citation:
  ama: Sethi S, Haiman Z. Can we detect the anisotropic shapes of quasar H ii regions
    during reionization through the small‐scale redshifted 21 cm power spectrum? <i>The
    Astrophysical Journal</i>. 2008;673(1):1-13. doi:<a href="https://doi.org/10.1086/523787">10.1086/523787</a>
  apa: Sethi, S., &#38; Haiman, Z. (2008). Can we detect the anisotropic shapes of
    quasar H ii regions during reionization through the small‐scale redshifted 21
    cm power spectrum? <i>The Astrophysical Journal</i>. American Astronomical Society.
    <a href="https://doi.org/10.1086/523787">https://doi.org/10.1086/523787</a>
  chicago: Sethi, Shiv, and Zoltán Haiman. “Can We Detect the Anisotropic Shapes of
    Quasar H Ii Regions during Reionization through the Small‐scale Redshifted 21
    Cm Power Spectrum?” <i>The Astrophysical Journal</i>. American Astronomical Society,
    2008. <a href="https://doi.org/10.1086/523787">https://doi.org/10.1086/523787</a>.
  ieee: S. Sethi and Z. Haiman, “Can we detect the anisotropic shapes of quasar H
    ii regions during reionization through the small‐scale redshifted 21 cm power
    spectrum?,” <i>The Astrophysical Journal</i>, vol. 673, no. 1. American Astronomical
    Society, pp. 1–13, 2008.
  ista: Sethi S, Haiman Z. 2008. Can we detect the anisotropic shapes of quasar H
    ii regions during reionization through the small‐scale redshifted 21 cm power
    spectrum? The Astrophysical Journal. 673(1), 1–13.
  mla: Sethi, Shiv, and Zoltán Haiman. “Can We Detect the Anisotropic Shapes of Quasar
    H Ii Regions during Reionization through the Small‐scale Redshifted 21 Cm Power
    Spectrum?” <i>The Astrophysical Journal</i>, vol. 673, no. 1, American Astronomical
    Society, 2008, pp. 1–13, doi:<a href="https://doi.org/10.1086/523787">10.1086/523787</a>.
  short: S. Sethi, Z. Haiman, The Astrophysical Journal 673 (2008) 1–13.
date_created: 2024-09-06T10:21:39Z
date_published: 2008-01-20T00:00:00Z
date_updated: 2024-09-30T13:47:04Z
day: '20'
doi: 10.1086/523787
extern: '1'
intvolume: '       673'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1086/523787
month: '01'
oa: 1
oa_version: Published Version
page: 1-13
publication: The Astrophysical Journal
publication_identifier:
  issn:
  - 0004-637X
  - 1538-4357
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Can we detect the anisotropic shapes of quasar H ii regions during reionization
  through the small‐scale redshifted 21 cm power spectrum?
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 673
year: '2008'
...
---
OA_place: repository
OA_type: free access
_id: '17804'
abstract:
- lang: eng
  text: Primordial gas in protogalactic DM halos with virial temperatures Tvir≳ 104
    K begins to cool and condense via atomic hydrogen. Provided that this gas is irradiated
    by a strong UV flux and remains free of H2 and other molecules, it has been proposed
    that the halo with Tvir ∼ 104 K may avoid fragmentation and lead to the rapid
    formation of an SMBH as massive as M ≈ 105–106 M☉. This "head start" would help
    explain the presence of SMBHs with inferred masses of several times 109 M☉, powering
    the bright quasars discovered in the SDSS at redshift z≳ 6. However, high-redshift
    DM halos with Tvir ∼ 104 K are likely already enriched with at least trace amounts
    of metals and dust produced by prior star formation in their progenitors. Here
    we study the thermal and chemical evolution of low-metallicity gas exposed to
    extremely strong UV radiation fields. Our results, obtained in one-zone models,
    suggest that gas fragmentation is inevitable above a critical metallicity, whose
    value is between Zcr ≈ 3 × 10−4 Z☉ (in the absence of dust) and as low as Zcr
    ≈ 5 × 10−6 Z☉ (with a dust-to-gas mass ratio of about 0.01Z/Z☉). We propose that
    when the metallicity exceeds these critical values, dense clusters of low-mass
    stars may form at the halo nucleus. Relatively massive stars in such a cluster
    can then rapidly coalesce into a single more massive object, which may produce
    an intermediate-mass BH remnant with a mass up to M≲ 102–103 M☉.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: K.
  full_name: Omukai, K.
  last_name: Omukai
- first_name: R.
  full_name: Schneider, R.
  last_name: Schneider
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
  orcid: 0000-0003-3633-5403
citation:
  ama: Omukai K, Schneider R, Haiman Z. Can supermassive black holes form in metal‐enriched
    high‐redshift protogalaxies? <i>The Astrophysical Journal</i>. 2008;686(2):801-814.
    doi:<a href="https://doi.org/10.1086/591636">10.1086/591636</a>
  apa: Omukai, K., Schneider, R., &#38; Haiman, Z. (2008). Can supermassive black
    holes form in metal‐enriched high‐redshift protogalaxies? <i>The Astrophysical
    Journal</i>. American Astronomical Society. <a href="https://doi.org/10.1086/591636">https://doi.org/10.1086/591636</a>
  chicago: Omukai, K., R. Schneider, and Zoltán Haiman. “Can Supermassive Black Holes
    Form in Metal‐enriched High‐redshift Protogalaxies?” <i>The Astrophysical Journal</i>.
    American Astronomical Society, 2008. <a href="https://doi.org/10.1086/591636">https://doi.org/10.1086/591636</a>.
  ieee: K. Omukai, R. Schneider, and Z. Haiman, “Can supermassive black holes form
    in metal‐enriched high‐redshift protogalaxies?,” <i>The Astrophysical Journal</i>,
    vol. 686, no. 2. American Astronomical Society, pp. 801–814, 2008.
  ista: Omukai K, Schneider R, Haiman Z. 2008. Can supermassive black holes form in
    metal‐enriched high‐redshift protogalaxies? The Astrophysical Journal. 686(2),
    801–814.
  mla: Omukai, K., et al. “Can Supermassive Black Holes Form in Metal‐enriched High‐redshift
    Protogalaxies?” <i>The Astrophysical Journal</i>, vol. 686, no. 2, American Astronomical
    Society, 2008, pp. 801–14, doi:<a href="https://doi.org/10.1086/591636">10.1086/591636</a>.
  short: K. Omukai, R. Schneider, Z. Haiman, The Astrophysical Journal 686 (2008)
    801–814.
date_created: 2024-09-06T11:33:03Z
date_published: 2008-08-20T00:00:00Z
date_updated: 2024-11-12T10:11:29Z
day: '20'
doi: 10.1086/591636
extern: '1'
external_id:
  arxiv:
  - '0804.3141'
intvolume: '       686'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.0804.3141
month: '08'
oa: 1
oa_version: Preprint
page: 801-814
publication: The Astrophysical Journal
publication_identifier:
  eissn:
  - 1538-4357
  issn:
  - 0004-637X
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Can supermassive black holes form in metal‐enriched high‐redshift protogalaxies?
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 686
year: '2008'
...
---
_id: '7752'
article_processing_charge: No
article_type: original
author:
- first_name: Matthew Richard
  full_name: Robinson, Matthew Richard
  id: E5D42276-F5DA-11E9-8E24-6303E6697425
  last_name: Robinson
  orcid: 0000-0001-8982-8813
- first_name: Jill G.
  full_name: Pilkington, Jill G.
  last_name: Pilkington
- first_name: Tim H.
  full_name: Clutton-Brock, Tim H.
  last_name: Clutton-Brock
- first_name: Josephine M.
  full_name: Pemberton, Josephine M.
  last_name: Pemberton
- first_name: Loeske. E.B.
  full_name: Kruuk, Loeske. E.B.
  last_name: Kruuk
citation:
  ama: Robinson MR, Pilkington JG, Clutton-Brock TH, Pemberton JM, Kruuk LEB. Environmental
    heterogeneity generates fluctuating selection on a secondary sexual trait. <i>Current
    Biology</i>. 2008;18(10):751-757. doi:<a href="https://doi.org/10.1016/j.cub.2008.04.059">10.1016/j.cub.2008.04.059</a>
  apa: Robinson, M. R., Pilkington, J. G., Clutton-Brock, T. H., Pemberton, J. M.,
    &#38; Kruuk, L. E. B. (2008). Environmental heterogeneity generates fluctuating
    selection on a secondary sexual trait. <i>Current Biology</i>. Elsevier. <a href="https://doi.org/10.1016/j.cub.2008.04.059">https://doi.org/10.1016/j.cub.2008.04.059</a>
  chicago: Robinson, Matthew Richard, Jill G. Pilkington, Tim H. Clutton-Brock, Josephine
    M. Pemberton, and Loeske. E.B. Kruuk. “Environmental Heterogeneity Generates Fluctuating
    Selection on a Secondary Sexual Trait.” <i>Current Biology</i>. Elsevier, 2008.
    <a href="https://doi.org/10.1016/j.cub.2008.04.059">https://doi.org/10.1016/j.cub.2008.04.059</a>.
  ieee: M. R. Robinson, J. G. Pilkington, T. H. Clutton-Brock, J. M. Pemberton, and
    L. E. B. Kruuk, “Environmental heterogeneity generates fluctuating selection on
    a secondary sexual trait,” <i>Current Biology</i>, vol. 18, no. 10. Elsevier,
    pp. 751–757, 2008.
  ista: Robinson MR, Pilkington JG, Clutton-Brock TH, Pemberton JM, Kruuk LEB. 2008.
    Environmental heterogeneity generates fluctuating selection on a secondary sexual
    trait. Current Biology. 18(10), 751–757.
  mla: Robinson, Matthew Richard, et al. “Environmental Heterogeneity Generates Fluctuating
    Selection on a Secondary Sexual Trait.” <i>Current Biology</i>, vol. 18, no. 10,
    Elsevier, 2008, pp. 751–57, doi:<a href="https://doi.org/10.1016/j.cub.2008.04.059">10.1016/j.cub.2008.04.059</a>.
  short: M.R. Robinson, J.G. Pilkington, T.H. Clutton-Brock, J.M. Pemberton, L.E.B.
    Kruuk, Current Biology 18 (2008) 751–757.
date_created: 2020-04-30T11:02:13Z
date_published: 2008-05-20T00:00:00Z
date_updated: 2021-01-12T08:15:17Z
day: '20'
doi: 10.1016/j.cub.2008.04.059
extern: '1'
intvolume: '        18'
issue: '10'
language:
- iso: eng
month: '05'
oa_version: None
page: 751-757
publication: Current Biology
publication_identifier:
  issn:
  - 0960-9822
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Environmental heterogeneity generates fluctuating selection on a secondary
  sexual trait
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 18
year: '2008'
...
---
_id: '844'
abstract:
- lang: eng
  text: Mutation rate varies greatly between nucleotide sites of the human genome
    and depends both on the global genomic location and the local sequence context
    of a site. In particular, CpG context elevates the mutation rate by an order of
    magnitude. Mutations also vary widely in their effect on the molecular function,
    phenotype, and fitness. Independence of the probability of occurrence of a new
    mutation's effect has been a fundamental premise in genetics. However, highly
    mutable contexts may be preserved by negative selection at important sites but
    destroyed by mutation at sites under no selection. Thus, there may be a positive
    correlation between the rate of mutations at a nucleotide site and the magnitude
    of their effect on fitness. We studied the impact of CpG context on the rate of
    human-chimpanzee divergence and on intrahuman nucleotide diversity at non-synonymous
    coding sites. We compared nucleotides that occupy identical positions within codons
    of identical amino acids and only differ by being within versus outside CpG context.
    Nucleotides within CpG context are under a stronger negative selection, as revealed
    by their lower, proportionally to the mutation rate, rate of evolution and nucleotide
    diversity. In particular, the probability of fixation of a non-synonymous transition
    at a CpG site is two times lower than at a CpG site. Thus, sites with different
    mutation rates are not necessarily selectively equivalent. This suggests that
    the mutation rate may complement sequence conservation as a characteristic predictive
    of functional importance of nucleotide sites.
acknowledgement: This work was supported in part by NIH grants R01 GM078598 and U54
  LM008748.
author:
- first_name: Steffen
  full_name: Schmidt, Steffen
  last_name: Schmidt
- first_name: Anna
  full_name: Gerasimova, Anna
  last_name: Gerasimova
- first_name: Fyodor
  full_name: Fyodor Kondrashov
  id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
  last_name: Kondrashov
  orcid: 0000-0001-8243-4694
- first_name: Ivan
  full_name: Adzuhbei, Ivan A
  last_name: Adzuhbei
- first_name: Alexey
  full_name: Kondrashov, Alexey S
  last_name: Kondrashov
- first_name: Shamil
  full_name: Sunyaev, Shamil R
  last_name: Sunyaev
citation:
  ama: Schmidt S, Gerasimova A, Kondrashov F, Adzuhbei I, Kondrashov A, Sunyaev S.
    Hypermutable non-synonymous sites are under stronger negative selection. <i>PLoS
    Genetics</i>. 2008;4(11). doi:<a href="https://doi.org/10.1371/journal.pgen.1000281">10.1371/journal.pgen.1000281</a>
  apa: Schmidt, S., Gerasimova, A., Kondrashov, F., Adzuhbei, I., Kondrashov, A.,
    &#38; Sunyaev, S. (2008). Hypermutable non-synonymous sites are under stronger
    negative selection. <i>PLoS Genetics</i>. Public Library of Science. <a href="https://doi.org/10.1371/journal.pgen.1000281">https://doi.org/10.1371/journal.pgen.1000281</a>
  chicago: Schmidt, Steffen, Anna Gerasimova, Fyodor Kondrashov, Ivan Adzuhbei, Alexey
    Kondrashov, and Shamil Sunyaev. “Hypermutable Non-Synonymous Sites Are under Stronger
    Negative Selection.” <i>PLoS Genetics</i>. Public Library of Science, 2008. <a
    href="https://doi.org/10.1371/journal.pgen.1000281">https://doi.org/10.1371/journal.pgen.1000281</a>.
  ieee: S. Schmidt, A. Gerasimova, F. Kondrashov, I. Adzuhbei, A. Kondrashov, and
    S. Sunyaev, “Hypermutable non-synonymous sites are under stronger negative selection,”
    <i>PLoS Genetics</i>, vol. 4, no. 11. Public Library of Science, 2008.
  ista: Schmidt S, Gerasimova A, Kondrashov F, Adzuhbei I, Kondrashov A, Sunyaev S.
    2008. Hypermutable non-synonymous sites are under stronger negative selection.
    PLoS Genetics. 4(11).
  mla: Schmidt, Steffen, et al. “Hypermutable Non-Synonymous Sites Are under Stronger
    Negative Selection.” <i>PLoS Genetics</i>, vol. 4, no. 11, Public Library of Science,
    2008, doi:<a href="https://doi.org/10.1371/journal.pgen.1000281">10.1371/journal.pgen.1000281</a>.
  short: S. Schmidt, A. Gerasimova, F. Kondrashov, I. Adzuhbei, A. Kondrashov, S.
    Sunyaev, PLoS Genetics 4 (2008).
date_created: 2018-12-11T11:48:48Z
date_published: 2008-11-01T00:00:00Z
date_updated: 2021-01-12T08:19:16Z
day: '01'
doi: 10.1371/journal.pgen.1000281
extern: 1
intvolume: '         4'
issue: '11'
license: https://creativecommons.org/licenses/by/4.0/
month: '11'
publication: PLoS Genetics
publication_status: published
publisher: Public Library of Science
publist_id: '6800'
quality_controlled: 0
status: public
title: Hypermutable non-synonymous sites are under stronger negative selection
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
volume: 4
year: '2008'
...
---
_id: '8480'
abstract:
- lang: eng
  text: The KIX domain of the transcription co-activator CBP is a three-helix bundle
    protein that folds via rapid accumulation of an intermediate state, followed by
    a slower folding phase. Recent NMR relaxation dispersion studies revealed the
    presence of a low-populated (excited) state of KIX that exists in equilibrium
    with the natively folded form under non-denaturing conditions, and likely represents
    the equilibrium analog of the folding intermediate. Here, we combine amide hydrogen/deuterium
    exchange measurements using rapid NMR data acquisition techniques with backbone
    15N and 13C relaxation dispersion experiments to further investigate the equilibrium
    folding of the KIX domain. Residual structure within the folding intermediate
    is detected by both methods, and their combination enables reliable quantification
    of the amount of persistent residual structure. Three well-defined folding subunits
    are found, which display variable stability and correspond closely to the individual
    helices in the native state. While two of the three helices (α2 and α3) are partially
    formed in the folding intermediate (to ∼ 50% and ∼ 80%, respectively, at 20 °C),
    the third helix is disordered. The observed helical content within the excited
    state exceeds the helical propensities predicted for the corresponding peptide
    regions, suggesting that the two helices are weakly mutually stabilized, while
    methyl 13C relaxation dispersion data indicate that a defined packing arrangement
    is unlikely. Temperature-dependent experiments reveal that the largest enthalpy
    and entropy changes along the folding reaction occur during the final transition
    from the intermediate to the native state. Our experimental data are consistent
    with a folding mechanism where helices α2 and α3 form rapidly, although to different
    extents, while helix α1 consolidates only as folding proceeds to complete the
    native state-structure.
article_processing_charge: No
article_type: original
author:
- first_name: Paul
  full_name: Schanda, Paul
  id: 7B541462-FAF6-11E9-A490-E8DFE5697425
  last_name: Schanda
  orcid: 0000-0002-9350-7606
- first_name: Bernhard
  full_name: Brutscher, Bernhard
  last_name: Brutscher
- first_name: Robert
  full_name: Konrat, Robert
  last_name: Konrat
- first_name: Martin
  full_name: Tollinger, Martin
  last_name: Tollinger
citation:
  ama: 'Schanda P, Brutscher B, Konrat R, Tollinger M. Folding of the KIX domain:
    Characterization of the equilibrium analog of a folding intermediate using 15N/13C
    relaxation dispersion and fast 1H/2H amide exchange NMR spectroscopy. <i>Journal
    of Molecular Biology</i>. 2008;380(4):726-741. doi:<a href="https://doi.org/10.1016/j.jmb.2008.05.040">10.1016/j.jmb.2008.05.040</a>'
  apa: 'Schanda, P., Brutscher, B., Konrat, R., &#38; Tollinger, M. (2008). Folding
    of the KIX domain: Characterization of the equilibrium analog of a folding intermediate
    using 15N/13C relaxation dispersion and fast 1H/2H amide exchange NMR spectroscopy.
    <i>Journal of Molecular Biology</i>. Elsevier. <a href="https://doi.org/10.1016/j.jmb.2008.05.040">https://doi.org/10.1016/j.jmb.2008.05.040</a>'
  chicago: 'Schanda, Paul, Bernhard Brutscher, Robert Konrat, and Martin Tollinger.
    “Folding of the KIX Domain: Characterization of the Equilibrium Analog of a Folding
    Intermediate Using 15N/13C Relaxation Dispersion and Fast 1H/2H Amide Exchange
    NMR Spectroscopy.” <i>Journal of Molecular Biology</i>. Elsevier, 2008. <a href="https://doi.org/10.1016/j.jmb.2008.05.040">https://doi.org/10.1016/j.jmb.2008.05.040</a>.'
  ieee: 'P. Schanda, B. Brutscher, R. Konrat, and M. Tollinger, “Folding of the KIX
    domain: Characterization of the equilibrium analog of a folding intermediate using
    15N/13C relaxation dispersion and fast 1H/2H amide exchange NMR spectroscopy,”
    <i>Journal of Molecular Biology</i>, vol. 380, no. 4. Elsevier, pp. 726–741, 2008.'
  ista: 'Schanda P, Brutscher B, Konrat R, Tollinger M. 2008. Folding of the KIX domain:
    Characterization of the equilibrium analog of a folding intermediate using 15N/13C
    relaxation dispersion and fast 1H/2H amide exchange NMR spectroscopy. Journal
    of Molecular Biology. 380(4), 726–741.'
  mla: 'Schanda, Paul, et al. “Folding of the KIX Domain: Characterization of the
    Equilibrium Analog of a Folding Intermediate Using 15N/13C Relaxation Dispersion
    and Fast 1H/2H Amide Exchange NMR Spectroscopy.” <i>Journal of Molecular Biology</i>,
    vol. 380, no. 4, Elsevier, 2008, pp. 726–41, doi:<a href="https://doi.org/10.1016/j.jmb.2008.05.040">10.1016/j.jmb.2008.05.040</a>.'
  short: P. Schanda, B. Brutscher, R. Konrat, M. Tollinger, Journal of Molecular Biology
    380 (2008) 726–741.
date_created: 2020-09-18T10:12:29Z
date_published: 2008-07-18T00:00:00Z
date_updated: 2021-01-12T08:19:34Z
day: '18'
doi: 10.1016/j.jmb.2008.05.040
extern: '1'
intvolume: '       380'
issue: '4'
keyword:
- Molecular Biology
language:
- iso: eng
month: '07'
oa_version: None
page: 726-741
publication: Journal of Molecular Biology
publication_identifier:
  issn:
  - 0022-2836
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: 'Folding of the KIX domain: Characterization of the equilibrium analog of a
  folding intermediate using 15N/13C relaxation dispersion and fast 1H/2H amide exchange
  NMR spectroscopy'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 380
year: '2008'
...
---
_id: '8481'
abstract:
- lang: eng
  text: 'The copK gene is localized on the pMOL30 plasmid of Cupriavidus metallidurans
    CH34 within the complex cop cluster of genes, for which 21 genes have been identified.
    The expression of the corresponding periplasmic CopK protein is strongly upregulated
    in the presence of copper, leading to a high periplasmic accumulation. The structure
    and metal-binding properties of CopK were investigated by NMR and mass spectrometry.
    The protein is dimeric in the apo state with a dissociation constant in the range
    of 10- 5 M estimated from analytical ultracentrifugation. Mass spectrometry revealed
    that CopK has two high-affinity Cu(I)-binding sites per monomer with different
    Cu(I) affinities. Binding of Cu(II) was observed but appeared to be non-specific.
    The solution structure of apo-CopK revealed an all-β fold formed of two β-sheets
    in perpendicular orientation with an unstructured C-terminal tail. The dimer interface
    is formed by the surface of the C-terminal β-sheet. Binding of the first Cu(I)-ion
    induces a major structural modification involving dissociation of the dimeric
    apo-protein. Backbone chemical shifts determined for the 1Cu(I)-bound form confirm
    the conservation of the N-terminal β-sheet, while the last strand of the C-terminal
    sheet appears in slow conformational exchange. We hypothesize that the partial
    disruption of the C-terminal β-sheet is related to dimer dissociation. NH-exchange
    data acquired on the apo-protein are consistent with a lower thermodynamic stability
    of the C-terminal sheet. CopK contains seven methionine residues, five of which
    appear highly conserved. Chemical shift data suggest implication of two or three
    methionines (Met54, Met38, Met28) in the first Cu(I) site. Addition of a second
    Cu(I) ion further increases protein plasticity. Comparison of the structural and
    metal-binding properties of CopK with other periplasmic copper-binding proteins
    reveals two conserved features within these functionally related proteins: the
    all-β fold and the methionine-rich Cu(I)-binding site.'
article_processing_charge: No
article_type: original
author:
- first_name: Beate
  full_name: Bersch, Beate
  last_name: Bersch
- first_name: Adrien
  full_name: Favier, Adrien
  last_name: Favier
- first_name: Paul
  full_name: Schanda, Paul
  id: 7B541462-FAF6-11E9-A490-E8DFE5697425
  last_name: Schanda
  orcid: 0000-0002-9350-7606
- first_name: Sébastien
  full_name: van Aelst, Sébastien
  last_name: van Aelst
- first_name: Tatiana
  full_name: Vallaeys, Tatiana
  last_name: Vallaeys
- first_name: Jacques
  full_name: Covès, Jacques
  last_name: Covès
- first_name: Max
  full_name: Mergeay, Max
  last_name: Mergeay
- first_name: Ruddy
  full_name: Wattiez, Ruddy
  last_name: Wattiez
citation:
  ama: Bersch B, Favier A, Schanda P, et al. Molecular structure and metal-binding
    properties of the periplasmic CopK protein expressed in Cupriavidus metallidurans
    CH34 during copper challenge. <i>Journal of Molecular Biology</i>. 2008;380(2):386-403.
    doi:<a href="https://doi.org/10.1016/j.jmb.2008.05.017">10.1016/j.jmb.2008.05.017</a>
  apa: Bersch, B., Favier, A., Schanda, P., van Aelst, S., Vallaeys, T., Covès, J.,
    … Wattiez, R. (2008). Molecular structure and metal-binding properties of the
    periplasmic CopK protein expressed in Cupriavidus metallidurans CH34 during copper
    challenge. <i>Journal of Molecular Biology</i>. Elsevier. <a href="https://doi.org/10.1016/j.jmb.2008.05.017">https://doi.org/10.1016/j.jmb.2008.05.017</a>
  chicago: Bersch, Beate, Adrien Favier, Paul Schanda, Sébastien van Aelst, Tatiana
    Vallaeys, Jacques Covès, Max Mergeay, and Ruddy Wattiez. “Molecular Structure
    and Metal-Binding Properties of the Periplasmic CopK Protein Expressed in Cupriavidus
    Metallidurans CH34 during Copper Challenge.” <i>Journal of Molecular Biology</i>.
    Elsevier, 2008. <a href="https://doi.org/10.1016/j.jmb.2008.05.017">https://doi.org/10.1016/j.jmb.2008.05.017</a>.
  ieee: B. Bersch <i>et al.</i>, “Molecular structure and metal-binding properties
    of the periplasmic CopK protein expressed in Cupriavidus metallidurans CH34 during
    copper challenge,” <i>Journal of Molecular Biology</i>, vol. 380, no. 2. Elsevier,
    pp. 386–403, 2008.
  ista: Bersch B, Favier A, Schanda P, van Aelst S, Vallaeys T, Covès J, Mergeay M,
    Wattiez R. 2008. Molecular structure and metal-binding properties of the periplasmic
    CopK protein expressed in Cupriavidus metallidurans CH34 during copper challenge.
    Journal of Molecular Biology. 380(2), 386–403.
  mla: Bersch, Beate, et al. “Molecular Structure and Metal-Binding Properties of
    the Periplasmic CopK Protein Expressed in Cupriavidus Metallidurans CH34 during
    Copper Challenge.” <i>Journal of Molecular Biology</i>, vol. 380, no. 2, Elsevier,
    2008, pp. 386–403, doi:<a href="https://doi.org/10.1016/j.jmb.2008.05.017">10.1016/j.jmb.2008.05.017</a>.
  short: B. Bersch, A. Favier, P. Schanda, S. van Aelst, T. Vallaeys, J. Covès, M.
    Mergeay, R. Wattiez, Journal of Molecular Biology 380 (2008) 386–403.
date_created: 2020-09-18T10:12:37Z
date_published: 2008-07-04T00:00:00Z
date_updated: 2021-01-12T08:19:34Z
day: '04'
doi: 10.1016/j.jmb.2008.05.017
extern: '1'
intvolume: '       380'
issue: '2'
keyword:
- Molecular Biology
language:
- iso: eng
month: '07'
oa_version: None
page: 386-403
publication: Journal of Molecular Biology
publication_identifier:
  issn:
  - 0022-2836
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Molecular structure and metal-binding properties of the periplasmic CopK protein
  expressed in Cupriavidus metallidurans CH34 during copper challenge
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 380
year: '2008'
...
---
_id: '8482'
abstract:
- lang: eng
  text: The SOFAST-HMQC experiment [P. Schanda, B. Brutscher, Very fast two-dimensional
    NMR spectroscopy for real-time investigation of dynamic events in proteins on
    the time scale of seconds, J. Am. Chem. Soc. 127 (2005) 8014–8015] allows recording
    two-dimensional correlation spectra of macromolecules such as proteins in only
    a few seconds acquisition time. To achieve the highest possible sensitivity, SOFAST-HMQC
    experiments are preferably performed on high-field NMR spectrometers equipped
    with cryogenically cooled probes. The duty cycle of over 80% in fast-pulsing SOFAST-HMQC
    experiments, however, may cause problems when using a cryogenic probe. Here we
    introduce SE-IPAP-SOFAST-HMQC, a new pulse sequence that provides comparable sensitivity
    to standard SOFAST-HMQC, while avoiding heteronuclear decoupling during 1H detection,
    and thus significantly reducing the radiofrequency load of the probe during the
    experiment. The experiment is also attractive for fast and sensitive measurement
    of heteronuclear one-bond spin coupling constants.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Thomas
  full_name: Kern, Thomas
  last_name: Kern
- first_name: Paul
  full_name: Schanda, Paul
  id: 7B541462-FAF6-11E9-A490-E8DFE5697425
  last_name: Schanda
  orcid: 0000-0002-9350-7606
- first_name: Bernhard
  full_name: Brutscher, Bernhard
  last_name: Brutscher
citation:
  ama: Kern T, Schanda P, Brutscher B. Sensitivity-enhanced IPAP-SOFAST-HMQC for fast-pulsing
    2D NMR with reduced radiofrequency load. <i>Journal of Magnetic Resonance</i>.
    2008;190(2):333-338. doi:<a href="https://doi.org/10.1016/j.jmr.2007.11.015">10.1016/j.jmr.2007.11.015</a>
  apa: Kern, T., Schanda, P., &#38; Brutscher, B. (2008). Sensitivity-enhanced IPAP-SOFAST-HMQC
    for fast-pulsing 2D NMR with reduced radiofrequency load. <i>Journal of Magnetic
    Resonance</i>. Elsevier. <a href="https://doi.org/10.1016/j.jmr.2007.11.015">https://doi.org/10.1016/j.jmr.2007.11.015</a>
  chicago: Kern, Thomas, Paul Schanda, and Bernhard Brutscher. “Sensitivity-Enhanced
    IPAP-SOFAST-HMQC for Fast-Pulsing 2D NMR with Reduced Radiofrequency Load.” <i>Journal
    of Magnetic Resonance</i>. Elsevier, 2008. <a href="https://doi.org/10.1016/j.jmr.2007.11.015">https://doi.org/10.1016/j.jmr.2007.11.015</a>.
  ieee: T. Kern, P. Schanda, and B. Brutscher, “Sensitivity-enhanced IPAP-SOFAST-HMQC
    for fast-pulsing 2D NMR with reduced radiofrequency load,” <i>Journal of Magnetic
    Resonance</i>, vol. 190, no. 2. Elsevier, pp. 333–338, 2008.
  ista: Kern T, Schanda P, Brutscher B. 2008. Sensitivity-enhanced IPAP-SOFAST-HMQC
    for fast-pulsing 2D NMR with reduced radiofrequency load. Journal of Magnetic
    Resonance. 190(2), 333–338.
  mla: Kern, Thomas, et al. “Sensitivity-Enhanced IPAP-SOFAST-HMQC for Fast-Pulsing
    2D NMR with Reduced Radiofrequency Load.” <i>Journal of Magnetic Resonance</i>,
    vol. 190, no. 2, Elsevier, 2008, pp. 333–38, doi:<a href="https://doi.org/10.1016/j.jmr.2007.11.015">10.1016/j.jmr.2007.11.015</a>.
  short: T. Kern, P. Schanda, B. Brutscher, Journal of Magnetic Resonance 190 (2008)
    333–338.
date_created: 2020-09-18T10:12:46Z
date_published: 2008-02-01T00:00:00Z
date_updated: 2021-01-12T08:19:35Z
day: '01'
doi: 10.1016/j.jmr.2007.11.015
extern: '1'
intvolume: '       190'
issue: '2'
keyword:
- Nuclear and High Energy Physics
- Biophysics
- Biochemistry
- Condensed Matter Physics
language:
- iso: eng
month: '02'
oa_version: None
page: 333-338
publication: Journal of Magnetic Resonance
publication_identifier:
  issn:
  - 1090-7807
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Sensitivity-enhanced IPAP-SOFAST-HMQC for fast-pulsing 2D NMR with reduced
  radiofrequency load
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 190
year: '2008'
...
---
_id: '8509'
abstract:
- lang: eng
  text: The goal of this paper is to present to nonspecialists what is perhaps the
    simplest possible geometrical picture explaining the mechanism of Arnold diffusion.
    We choose to speak of a specific model—that of geometric rays in a periodic optical
    medium. This model is equivalent to that of a particle in a periodic potential
    in ${\mathbb R}^{n}$ with energy prescribed and to the geodesic flow in a Riemannian
    metric on ${\mathbb R}^{n} $.
article_processing_charge: No
article_type: original
author:
- first_name: Vadim
  full_name: Kaloshin, Vadim
  id: FE553552-CDE8-11E9-B324-C0EBE5697425
  last_name: Kaloshin
  orcid: 0000-0002-6051-2628
- first_name: Mark
  full_name: Levi, Mark
  last_name: Levi
citation:
  ama: Kaloshin V, Levi M. Geometry of Arnold diffusion. <i>SIAM Review</i>. 2008;50(4):702-720.
    doi:<a href="https://doi.org/10.1137/070703235">10.1137/070703235</a>
  apa: Kaloshin, V., &#38; Levi, M. (2008). Geometry of Arnold diffusion. <i>SIAM
    Review</i>. Society for Industrial &#38; Applied Mathematics. <a href="https://doi.org/10.1137/070703235">https://doi.org/10.1137/070703235</a>
  chicago: Kaloshin, Vadim, and Mark Levi. “Geometry of Arnold Diffusion.” <i>SIAM
    Review</i>. Society for Industrial &#38; Applied Mathematics, 2008. <a href="https://doi.org/10.1137/070703235">https://doi.org/10.1137/070703235</a>.
  ieee: V. Kaloshin and M. Levi, “Geometry of Arnold diffusion,” <i>SIAM Review</i>,
    vol. 50, no. 4. Society for Industrial &#38; Applied Mathematics, pp. 702–720,
    2008.
  ista: Kaloshin V, Levi M. 2008. Geometry of Arnold diffusion. SIAM Review. 50(4),
    702–720.
  mla: Kaloshin, Vadim, and Mark Levi. “Geometry of Arnold Diffusion.” <i>SIAM Review</i>,
    vol. 50, no. 4, Society for Industrial &#38; Applied Mathematics, 2008, pp. 702–20,
    doi:<a href="https://doi.org/10.1137/070703235">10.1137/070703235</a>.
  short: V. Kaloshin, M. Levi, SIAM Review 50 (2008) 702–720.
date_created: 2020-09-18T10:48:12Z
date_published: 2008-11-05T00:00:00Z
date_updated: 2021-01-12T08:19:46Z
day: '05'
doi: 10.1137/070703235
extern: '1'
intvolume: '        50'
issue: '4'
keyword:
- Theoretical Computer Science
- Applied Mathematics
- Computational Mathematics
language:
- iso: eng
month: '11'
oa_version: None
page: 702-720
publication: SIAM Review
publication_identifier:
  issn:
  - 0036-1445
  - 1095-7200
publication_status: published
publisher: Society for Industrial & Applied Mathematics
quality_controlled: '1'
status: public
title: Geometry of Arnold diffusion
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 50
year: '2008'
...
