---
_id: '4392'
abstract:
- lang: eng
  text: 'While a boolean notion of correctness is given by a preorder on systems and
    properties, a quantitative notion of correctness is defined by a distance function
    on systems and properties, where the distance between a system and a property
    provides a measure of “fit” or “desirability.” In this article, we explore several
    ways how the simulation preorder can be generalized to a distance function. This
    is done by equipping the classical simulation game between a system and a property
    with quantitative objectives. In particular, for systems that satisfy a property,
    a quantitative simulation game can measure the “robustness” of the satisfaction,
    that is, how much the system can deviate from its nominal behavior while still
    satisfying the property. For systems that violate a property, a quantitative simulation
    game can measure the “seriousness” of the violation, that is, how much the property
    has to be modified so that it is satisfied by the system. These distances can
    be computed in polynomial time, since the computation reduces to the value problem
    in limit average games with constant weights. Finally, we demonstrate how the
    robustness distance can be used to measure how many transmission errors are tolerated
    by error correcting codes. '
alternative_title:
- LNCS
author:
- first_name: Pavol
  full_name: Cerny, Pavol
  id: 4DCBEFFE-F248-11E8-B48F-1D18A9856A87
  last_name: Cerny
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Arjun
  full_name: Radhakrishna, Arjun
  id: 3B51CAC4-F248-11E8-B48F-1D18A9856A87
  last_name: Radhakrishna
citation:
  ama: 'Cerny P, Henzinger TA, Radhakrishna A. Quantitative Simulation Games. In:
    Manna Z, Peled D, eds. <i>Time For Verification: Essays in Memory of Amir Pnueli</i>.
    Vol 6200. Essays in Memory of Amir Pnueli. Springer; 2010:42-60. doi:<a href="https://doi.org/10.1007/978-3-642-13754-9_3">10.1007/978-3-642-13754-9_3</a>'
  apa: 'Cerny, P., Henzinger, T. A., &#38; Radhakrishna, A. (2010). Quantitative Simulation
    Games. In Z. Manna &#38; D. Peled (Eds.), <i>Time For Verification: Essays in
    Memory of Amir Pnueli</i> (Vol. 6200, pp. 42–60). Springer. <a href="https://doi.org/10.1007/978-3-642-13754-9_3">https://doi.org/10.1007/978-3-642-13754-9_3</a>'
  chicago: 'Cerny, Pavol, Thomas A Henzinger, and Arjun Radhakrishna. “Quantitative
    Simulation Games.” In <i>Time For Verification: Essays in Memory of Amir Pnueli</i>,
    edited by Zohar Manna and Doron Peled, 6200:42–60. Essays in Memory of Amir Pnueli.
    Springer, 2010. <a href="https://doi.org/10.1007/978-3-642-13754-9_3">https://doi.org/10.1007/978-3-642-13754-9_3</a>.'
  ieee: 'P. Cerny, T. A. Henzinger, and A. Radhakrishna, “Quantitative Simulation
    Games,” in <i>Time For Verification: Essays in Memory of Amir Pnueli</i>, vol.
    6200, Z. Manna and D. Peled, Eds. Springer, 2010, pp. 42–60.'
  ista: 'Cerny P, Henzinger TA, Radhakrishna A. 2010.Quantitative Simulation Games.
    In: Time For Verification: Essays in Memory of Amir Pnueli. LNCS, vol. 6200, 42–60.'
  mla: 'Cerny, Pavol, et al. “Quantitative Simulation Games.” <i>Time For Verification:
    Essays in Memory of Amir Pnueli</i>, edited by Zohar Manna and Doron Peled, vol.
    6200, Springer, 2010, pp. 42–60, doi:<a href="https://doi.org/10.1007/978-3-642-13754-9_3">10.1007/978-3-642-13754-9_3</a>.'
  short: 'P. Cerny, T.A. Henzinger, A. Radhakrishna, in:, Z. Manna, D. Peled (Eds.),
    Time For Verification: Essays in Memory of Amir Pnueli, Springer, 2010, pp. 42–60.'
corr_author: '1'
date_created: 2018-12-11T12:08:37Z
date_published: 2010-07-29T00:00:00Z
date_updated: 2024-10-09T20:53:58Z
day: '29'
department:
- _id: ToHe
doi: 10.1007/978-3-642-13754-9_3
ec_funded: 1
editor:
- first_name: Zohar
  full_name: Manna, Zohar
  last_name: Manna
- first_name: Doron
  full_name: Peled, Doron
  last_name: Peled
fulldoi: https://doi.org/10.1007/978-3-642-13754-9_3
intvolume: '      6200'
language:
- iso: eng
month: '07'
oa_version: None
page: 42 - 60
project:
- _id: 25EFB36C-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '215543'
  name: COMponent-Based Embedded Systems design Techniques
- _id: 25F1337C-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '214373'
  name: Design for Embedded Systems
publication: 'Time For Verification: Essays in Memory of Amir Pnueli'
publication_status: published
publisher: Springer
publist_id: '1064'
quality_controlled: '1'
scopus_import: 1
series_title: Essays in Memory of Amir Pnueli
status: public
title: Quantitative Simulation Games
type: book_chapter
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 6200
year: '2010'
...
---
_id: '4393'
abstract:
- lang: eng
  text: Boolean notions of correctness are formalized by preorders on systems. Quantitative
    measures of correctness can be formalized by real-valued distance functions between
    systems, where the distance between implementation and specification provides
    a measure of “fit” or “desirability.” We extend the simulation preorder to the
    quantitative setting, by making each player of a simulation game pay a certain
    price for her choices. We use the resulting games with quantitative objectives
    to define three different simulation distances. The correctness distance measures
    how much the specification must be changed in order to be satisfied by the implementation.
    The coverage distance measures how much the implementation restricts the degrees
    of freedom offered by the specification. The robustness distance measures how
    much a system can deviate from the implementation description without violating
    the specification. We consider these distances for safety as well as liveness
    specifications. The distances can be computed in polynomial time for safety specifications,
    and for liveness specifications given by weak fairness constraints. We show that
    the distance functions satisfy the triangle inequality, that the distance between
    two systems does not increase under parallel composition with a third system,
    and that the distance between two systems can be bounded from above and below
    by distances between abstractions of the two systems. These properties suggest
    that our simulation distances provide an appropriate basis for a quantitative
    theory of discrete systems. We also demonstrate how the robustness distance can
    be used to measure how many transmission errors are tolerated by error correcting
    codes.
acknowledgement: This work was partially supported by the European Union project COMBEST
  and the European Network of Excellence ArtistDesign.
alternative_title:
- LNCS
author:
- first_name: Pavol
  full_name: Cerny, Pavol
  id: 4DCBEFFE-F248-11E8-B48F-1D18A9856A87
  last_name: Cerny
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Arjun
  full_name: Radhakrishna, Arjun
  id: 3B51CAC4-F248-11E8-B48F-1D18A9856A87
  last_name: Radhakrishna
citation:
  ama: 'Cerny P, Henzinger TA, Radhakrishna A. Simulation distances. In: Vol 6269.
    Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2010:235-268. doi:<a href="https://doi.org/10.1007/978-3-642-15375-4_18">10.1007/978-3-642-15375-4_18</a>'
  apa: 'Cerny, P., Henzinger, T. A., &#38; Radhakrishna, A. (2010). Simulation distances
    (Vol. 6269, pp. 235–268). Presented at the CONCUR: Concurrency Theory, Paris,
    France: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href="https://doi.org/10.1007/978-3-642-15375-4_18">https://doi.org/10.1007/978-3-642-15375-4_18</a>'
  chicago: Cerny, Pavol, Thomas A Henzinger, and Arjun Radhakrishna. “Simulation Distances,”
    6269:235–68. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2010. <a href="https://doi.org/10.1007/978-3-642-15375-4_18">https://doi.org/10.1007/978-3-642-15375-4_18</a>.
  ieee: 'P. Cerny, T. A. Henzinger, and A. Radhakrishna, “Simulation distances,” presented
    at the CONCUR: Concurrency Theory, Paris, France, 2010, vol. 6269, pp. 235–268.'
  ista: 'Cerny P, Henzinger TA, Radhakrishna A. 2010. Simulation distances. CONCUR:
    Concurrency Theory, LNCS, vol. 6269, 235–268.'
  mla: Cerny, Pavol, et al. <i>Simulation Distances</i>. Vol. 6269, Schloss Dagstuhl
    - Leibniz-Zentrum für Informatik, 2010, pp. 235–68, doi:<a href="https://doi.org/10.1007/978-3-642-15375-4_18">10.1007/978-3-642-15375-4_18</a>.
  short: P. Cerny, T.A. Henzinger, A. Radhakrishna, in:, Schloss Dagstuhl - Leibniz-Zentrum
    für Informatik, 2010, pp. 235–268.
conference:
  end_date: 2010-09-03
  location: Paris, France
  name: 'CONCUR: Concurrency Theory'
  start_date: 2010-08-31
corr_author: '1'
date_created: 2018-12-11T12:08:37Z
date_published: 2010-11-01T00:00:00Z
date_updated: 2026-06-18T18:41:23Z
day: '01'
ddc:
- '005'
department:
- _id: ToHe
doi: 10.1007/978-3-642-15375-4_18
ec_funded: 1
file:
- access_level: open_access
  checksum: ea567903676ba8afe0507ee11313dce5
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:15:12Z
  date_updated: 2020-07-14T12:46:28Z
  file_id: '5130'
  file_name: IST-2012-42-v1+1_Simulation_distances.pdf
  file_size: 198913
  relation: main_file
file_date_updated: 2020-07-14T12:46:28Z
fulldoi: https://doi.org/10.1007/978-3-642-15375-4_18
has_accepted_license: '1'
intvolume: '      6269'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Submitted Version
page: 235 - 268
project:
- _id: 25EFB36C-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '215543'
  name: COMponent-Based Embedded Systems design Techniques
- _id: 25F1337C-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '214373'
  name: Design for Embedded Systems
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '1065'
pubrep_id: '42'
quality_controlled: '1'
related_material:
  record:
  - id: '5389'
    relation: earlier_version
    status: public
  - id: '3249'
    relation: later_version
    status: public
scopus_import: 1
status: public
title: Simulation distances
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 6269
year: '2010'
...
---
_id: '4395'
abstract:
- lang: eng
  text: The problem of locally transforming or translating programs without altering
    their semantics is central to the construction of correct compilers. For concurrent
    shared-memory programs this task is challenging because (1) concurrent threads
    can observe transformations that would be undetectable in a sequential program,
    and (2) contemporary multiprocessors commonly use relaxed memory models that complicate
    the reasoning. In this paper, we present a novel proof methodology for verifying
    that a local program transformation is sound with respect to a specific hardware
    memory model, in the sense that it is not observable in any context. The methodology
    is based on a structural induction and relies on a novel compositional denotational
    semantics for relaxed memory models that formalizes (1) the behaviors of program
    fragments as a set of traces, and (2) the effect of memory model relaxations as
    local trace rewrite operations. To apply this methodology in practice, we implemented
    a semi- automated tool called Traver and used it to verify/falsify several compiler
    transformations for a number of different hardware memory models.
alternative_title:
- LNCS
author:
- first_name: Sebastian
  full_name: Burckhardt, Sebastian
  last_name: Burckhardt
- first_name: Madanlal
  full_name: Musuvathi, Madanlal
  last_name: Musuvathi
- first_name: Vasu
  full_name: Singh, Vasu
  id: 4DAE2708-F248-11E8-B48F-1D18A9856A87
  last_name: Singh
citation:
  ama: 'Burckhardt S, Musuvathi M, Singh V. Verifying local transformations on relaxed
    memory models. In: Gupta R, ed. Vol 6011. Springer; 2010:104-123. doi:<a href="https://doi.org/10.1007/978-3-642-11970-5_7">10.1007/978-3-642-11970-5_7</a>'
  apa: 'Burckhardt, S., Musuvathi, M., &#38; Singh, V. (2010). Verifying local transformations
    on relaxed memory models. In R. Gupta (Ed.) (Vol. 6011, pp. 104–123). Presented
    at the CC: Compiler Construction, Pahos, Cyprus: Springer. <a href="https://doi.org/10.1007/978-3-642-11970-5_7">https://doi.org/10.1007/978-3-642-11970-5_7</a>'
  chicago: Burckhardt, Sebastian, Madanlal Musuvathi, and Vasu Singh. “Verifying Local
    Transformations on Relaxed Memory Models.” edited by Rajiv Gupta, 6011:104–23.
    Springer, 2010. <a href="https://doi.org/10.1007/978-3-642-11970-5_7">https://doi.org/10.1007/978-3-642-11970-5_7</a>.
  ieee: 'S. Burckhardt, M. Musuvathi, and V. Singh, “Verifying local transformations
    on relaxed memory models,” presented at the CC: Compiler Construction, Pahos,
    Cyprus, 2010, vol. 6011, pp. 104–123.'
  ista: 'Burckhardt S, Musuvathi M, Singh V. 2010. Verifying local transformations
    on relaxed memory models. CC: Compiler Construction, LNCS, vol. 6011, 104–123.'
  mla: Burckhardt, Sebastian, et al. <i>Verifying Local Transformations on Relaxed
    Memory Models</i>. Edited by Rajiv Gupta, vol. 6011, Springer, 2010, pp. 104–23,
    doi:<a href="https://doi.org/10.1007/978-3-642-11970-5_7">10.1007/978-3-642-11970-5_7</a>.
  short: S. Burckhardt, M. Musuvathi, V. Singh, in:, R. Gupta (Ed.), Springer, 2010,
    pp. 104–123.
conference:
  end_date: 2010-03-28
  location: Pahos, Cyprus
  name: 'CC: Compiler Construction'
  start_date: 2010-03-20
date_created: 2018-12-11T12:08:38Z
date_published: 2010-04-21T00:00:00Z
date_updated: 2021-01-12T07:56:39Z
day: '21'
doi: 10.1007/978-3-642-11970-5_7
editor:
- first_name: Rajiv
  full_name: Gupta, Rajiv
  last_name: Gupta
extern: '1'
fulldoi: https://doi.org/10.1007/978-3-642-11970-5_7
intvolume: '      6011'
language:
- iso: eng
month: '04'
oa_version: None
page: 104 - 123
publication_status: published
publisher: Springer
publist_id: '1063'
quality_controlled: '1'
status: public
title: Verifying local transformations on relaxed memory models
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 6011
year: '2010'
...
---
_id: '4396'
abstract:
- lang: eng
  text: 'Shape analysis is a promising technique to prove program properties about
    recursive data structures. The challenge is to automatically determine the data-structure
    type, and to supply the shape analysis with the necessary information about the
    data structure. We present a stepwise approach to the selection of instrumentation
    predicates for a TVLA-based shape analysis, which takes us a step closer towards
    the fully automatic verification of data structures. The approach uses two techniques
    to guide the refinement of shape abstractions: (1) during program exploration,
    an explicit heap analysis collects sample instances of the heap structures, which
    are used to identify the data structures that are manipulated by the program;
    and (2) during abstraction refinement along an infeasible error path, we consider
    different possible heap abstractions and choose the coarsest one that eliminates
    the infeasible path. We have implemented this combined approach for automatic
    shape refinement as an extension of the software model checker BLAST. Example
    programs from a data-structure library that manipulate doubly-linked lists and
    trees were successfully verified by our tool.'
alternative_title:
- LNCS
author:
- first_name: Dirk
  full_name: Beyer, Dirk
  last_name: Beyer
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Grégory
  full_name: Théoduloz, Grégory
  last_name: Théoduloz
- first_name: Damien
  full_name: Zufferey, Damien
  id: 4397AC76-F248-11E8-B48F-1D18A9856A87
  last_name: Zufferey
  orcid: 0000-0002-3197-8736
citation:
  ama: 'Beyer D, Henzinger TA, Théoduloz G, Zufferey D. Shape refinement through explicit
    heap analysis. In: Rosenblum D, Taenzer G, eds. Vol 6013. Springer; 2010:263-277.
    doi:<a href="https://doi.org/10.1007/978-3-642-12029-9_19">10.1007/978-3-642-12029-9_19</a>'
  apa: 'Beyer, D., Henzinger, T. A., Théoduloz, G., &#38; Zufferey, D. (2010). Shape
    refinement through explicit heap analysis. In D. Rosenblum &#38; G. Taenzer (Eds.)
    (Vol. 6013, pp. 263–277). Presented at the FASE: Fundamental Approaches To Software
    Engineering, Paphos, Cyprus: Springer. <a href="https://doi.org/10.1007/978-3-642-12029-9_19">https://doi.org/10.1007/978-3-642-12029-9_19</a>'
  chicago: Beyer, Dirk, Thomas A Henzinger, Grégory Théoduloz, and Damien Zufferey.
    “Shape Refinement through Explicit Heap Analysis.” edited by David Rosenblum and
    Gabriele Taenzer, 6013:263–77. Springer, 2010. <a href="https://doi.org/10.1007/978-3-642-12029-9_19">https://doi.org/10.1007/978-3-642-12029-9_19</a>.
  ieee: 'D. Beyer, T. A. Henzinger, G. Théoduloz, and D. Zufferey, “Shape refinement
    through explicit heap analysis,” presented at the FASE: Fundamental Approaches
    To Software Engineering, Paphos, Cyprus, 2010, vol. 6013, pp. 263–277.'
  ista: 'Beyer D, Henzinger TA, Théoduloz G, Zufferey D. 2010. Shape refinement through
    explicit heap analysis. FASE: Fundamental Approaches To Software Engineering,
    LNCS, vol. 6013, 263–277.'
  mla: Beyer, Dirk, et al. <i>Shape Refinement through Explicit Heap Analysis</i>.
    Edited by David Rosenblum and Gabriele Taenzer, vol. 6013, Springer, 2010, pp.
    263–77, doi:<a href="https://doi.org/10.1007/978-3-642-12029-9_19">10.1007/978-3-642-12029-9_19</a>.
  short: D. Beyer, T.A. Henzinger, G. Théoduloz, D. Zufferey, in:, D. Rosenblum, G.
    Taenzer (Eds.), Springer, 2010, pp. 263–277.
conference:
  end_date: 2010-03-28
  location: Paphos, Cyprus
  name: 'FASE: Fundamental Approaches To Software Engineering'
  start_date: 2010-03-20
date_created: 2018-12-11T12:08:38Z
date_published: 2010-04-21T00:00:00Z
date_updated: 2021-01-12T07:56:40Z
day: '21'
ddc:
- '004'
department:
- _id: ToHe
doi: 10.1007/978-3-642-12029-9_19
editor:
- first_name: David
  full_name: Rosenblum, David
  last_name: Rosenblum
- first_name: Gabriele
  full_name: Taenzer, Gabriele
  last_name: Taenzer
file:
- access_level: open_access
  checksum: 7d26e59a9681487d7283eba337292b2c
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:18:13Z
  date_updated: 2020-07-14T12:46:29Z
  file_id: '5332'
  file_name: IST-2012-41-v1+1_Shape_refinement_through_explicit_heap_analysis.pdf
  file_size: 312147
  relation: main_file
file_date_updated: 2020-07-14T12:46:29Z
fulldoi: https://doi.org/10.1007/978-3-642-12029-9_19
has_accepted_license: '1'
intvolume: '      6013'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Submitted Version
page: 263 - 277
project:
- _id: 2587B514-B435-11E9-9278-68D0E5697425
  name: Microsoft Research Faculty Fellowship
publication_status: published
publisher: Springer
publist_id: '1061'
pubrep_id: '41'
quality_controlled: '1'
scopus_import: 1
status: public
title: Shape refinement through explicit heap analysis
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 6013
year: '2010'
...
---
_id: '474'
abstract:
- lang: eng
  text: 'Classical models of gene flow fail in three ways: they cannot explain large-scale
    patterns; they predict much more genetic diversity than is observed; and they
    assume that loosely linked genetic loci evolve independently. We propose a new
    model that deals with these problems. Extinction events kill some fraction of
    individuals in a region. These are replaced by offspring from a small number of
    parents, drawn from the preexisting population. This model of evolution forwards
    in time corresponds to a backwards model, in which ancestral lineages jump to
    a new location if they are hit by an event, and may coalesce with other lineages
    that are hit by the same event. We derive an expression for the identity in allelic
    state, and show that, over scales much larger than the largest event, this converges
    to the classical value derived by Wright and Malécot. However, rare events that
    cover large areas cause low genetic diversity, large-scale patterns, and correlations
    in ancestry between unlinked loci.'
acknowledgement: This work has made use of the resources provided by the Edinburgh
  Compute and Data Facility (ECDF). The ECDF is partially supported by the eDIKT initiative.
  NHB is supported in part by EPSRC Grant EP/E066070/1; JK is supported by EPSRC Grant
  EP/E066070/1; and AME is supported in part by EPSRC Grant EP/E065945/1.
article_processing_charge: No
author:
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Jerome
  full_name: Kelleher, Jerome
  last_name: Kelleher
- first_name: Alison
  full_name: Etheridge, Alison
  last_name: Etheridge
citation:
  ama: 'Barton NH, Kelleher J, Etheridge A. A new model for extinction and recolonization
    in two dimensions: Quantifying phylogeography. <i>Evolution</i>. 2010;64(9):2701-2715.
    doi:<a href="https://doi.org/10.1111/j.1558-5646.2010.01019.x">10.1111/j.1558-5646.2010.01019.x</a>'
  apa: 'Barton, N. H., Kelleher, J., &#38; Etheridge, A. (2010). A new model for extinction
    and recolonization in two dimensions: Quantifying phylogeography. <i>Evolution</i>.
    Wiley-Blackwell. <a href="https://doi.org/10.1111/j.1558-5646.2010.01019.x">https://doi.org/10.1111/j.1558-5646.2010.01019.x</a>'
  chicago: 'Barton, Nicholas H, Jerome Kelleher, and Alison Etheridge. “A New Model
    for Extinction and Recolonization in Two Dimensions: Quantifying Phylogeography.”
    <i>Evolution</i>. Wiley-Blackwell, 2010. <a href="https://doi.org/10.1111/j.1558-5646.2010.01019.x">https://doi.org/10.1111/j.1558-5646.2010.01019.x</a>.'
  ieee: 'N. H. Barton, J. Kelleher, and A. Etheridge, “A new model for extinction
    and recolonization in two dimensions: Quantifying phylogeography,” <i>Evolution</i>,
    vol. 64, no. 9. Wiley-Blackwell, pp. 2701–2715, 2010.'
  ista: 'Barton NH, Kelleher J, Etheridge A. 2010. A new model for extinction and
    recolonization in two dimensions: Quantifying phylogeography. Evolution. 64(9),
    2701–2715.'
  mla: 'Barton, Nicholas H., et al. “A New Model for Extinction and Recolonization
    in Two Dimensions: Quantifying Phylogeography.” <i>Evolution</i>, vol. 64, no.
    9, Wiley-Blackwell, 2010, pp. 2701–15, doi:<a href="https://doi.org/10.1111/j.1558-5646.2010.01019.x">10.1111/j.1558-5646.2010.01019.x</a>.'
  short: N.H. Barton, J. Kelleher, A. Etheridge, Evolution 64 (2010) 2701–2715.
corr_author: '1'
date_created: 2018-12-11T11:46:40Z
date_published: 2010-09-01T00:00:00Z
date_updated: 2025-09-30T09:50:22Z
day: '01'
department:
- _id: NiBa
doi: 10.1111/j.1558-5646.2010.01019.x
external_id:
  isi:
  - '000281636400017'
fulldoi: https://doi.org/10.1111/j.1558-5646.2010.01019.x
intvolume: '        64'
isi: 1
issue: '9'
language:
- iso: eng
month: '09'
oa_version: None
page: 2701 - 2715
publication: Evolution
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2780'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'A new model for extinction and recolonization in two dimensions: Quantifying
  phylogeography'
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 64
year: '2010'
...
---
_id: '488'
abstract:
- lang: eng
  text: 'Streaming string transducers [1] define (partial) functions from input strings
    to output strings. A streaming string transducer makes a single pass through the
    input string and uses a finite set of variables that range over strings from the
    output alphabet. At every step, the transducer processes an input symbol, and
    updates all the variables in parallel using assignments whose right-hand-sides
    are concatenations of output symbols and variables with the restriction that a
    variable can be used at most once in a right-hand-side expression. It has been
    shown that streaming string transducers operating on strings over infinite data
    domains are of interest in algorithmic verification of list-processing programs,
    as they lead to PSPACE decision procedures for checking pre/post conditions and
    for checking semantic equivalence, for a well-defined class of heap-manipulating
    programs. In order to understand the theoretical expressiveness of streaming transducers,
    we focus on streaming transducers processing strings over finite alphabets, given
    the existence of a robust and well-studied class of &quot;regular&quot; transductions
    for this case. Such regular transductions can be defined either by two-way deterministic
    finite-state transducers, or using a logical MSO-based characterization. Our main
    result is that the expressiveness of streaming string transducers coincides exactly
    with this class of regular transductions. '
alternative_title:
- LIPIcs
article_processing_charge: No
author:
- first_name: Rajeev
  full_name: Alur, Rajeev
  last_name: Alur
- first_name: Pavol
  full_name: Cerny, Pavol
  id: 4DCBEFFE-F248-11E8-B48F-1D18A9856A87
  last_name: Cerny
citation:
  ama: 'Alur R, Cerny P. Expressiveness of streaming string transducers. In: Vol 8.
    Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2010:1-12. doi:<a href="https://doi.org/10.4230/LIPIcs.FSTTCS.2010.1">10.4230/LIPIcs.FSTTCS.2010.1</a>'
  apa: 'Alur, R., &#38; Cerny, P. (2010). Expressiveness of streaming string transducers
    (Vol. 8, pp. 1–12). Presented at the FSTTCS: Foundations of Software Technology
    and Theoretical Computer Science, Chennai, India: Schloss Dagstuhl - Leibniz-Zentrum
    für Informatik. <a href="https://doi.org/10.4230/LIPIcs.FSTTCS.2010.1">https://doi.org/10.4230/LIPIcs.FSTTCS.2010.1</a>'
  chicago: Alur, Rajeev, and Pavol Cerny. “Expressiveness of Streaming String Transducers,”
    8:1–12. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2010. <a href="https://doi.org/10.4230/LIPIcs.FSTTCS.2010.1">https://doi.org/10.4230/LIPIcs.FSTTCS.2010.1</a>.
  ieee: 'R. Alur and P. Cerny, “Expressiveness of streaming string transducers,” presented
    at the FSTTCS: Foundations of Software Technology and Theoretical Computer Science,
    Chennai, India, 2010, vol. 8, pp. 1–12.'
  ista: 'Alur R, Cerny P. 2010. Expressiveness of streaming string transducers. FSTTCS:
    Foundations of Software Technology and Theoretical Computer Science, LIPIcs, vol.
    8, 1–12.'
  mla: Alur, Rajeev, and Pavol Cerny. <i>Expressiveness of Streaming String Transducers</i>.
    Vol. 8, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2010, pp. 1–12, doi:<a
    href="https://doi.org/10.4230/LIPIcs.FSTTCS.2010.1">10.4230/LIPIcs.FSTTCS.2010.1</a>.
  short: R. Alur, P. Cerny, in:, Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
    2010, pp. 1–12.
conference:
  end_date: 2010-12-18
  location: Chennai, India
  name: 'FSTTCS: Foundations of Software Technology and Theoretical Computer Science'
  start_date: 2010-12-15
corr_author: '1'
date_created: 2018-12-11T11:46:45Z
date_published: 2010-01-01T00:00:00Z
date_updated: 2025-09-30T09:49:32Z
day: '01'
ddc:
- '005'
department:
- _id: ToHe
doi: 10.4230/LIPIcs.FSTTCS.2010.1
external_id:
  isi:
  - '000310361000001'
file:
- access_level: open_access
  checksum: 5845be5aa19791830f7407d8853f2df0
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:08:29Z
  date_updated: 2020-07-14T12:46:35Z
  file_id: '4690'
  file_name: IST-2018-948-v1+1_2011_Cerny_Expressiveness_of.pdf
  file_size: 492344
  relation: main_file
file_date_updated: 2020-07-14T12:46:35Z
fulldoi: https://doi.org/10.4230/LIPIcs.FSTTCS.2010.1
has_accepted_license: '1'
intvolume: '         8'
isi: 1
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 1 - 12
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '7331'
pubrep_id: '948'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Expressiveness of streaming string transducers
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: conference
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 8
year: '2010'
...
---
_id: '489'
abstract:
- lang: eng
  text: 'Graph games of infinite length are a natural model for open reactive processes:
    one player represents the controller, trying to ensure a given specification,
    and the other represents a hostile environment. The evolution of the system depends
    on the decisions of both players, supplemented by chance. In this work, we focus
    on the notion of randomised strategy. More specifically, we show that three natural
    definitions may lead to very different results: in the most general cases, an
    almost-surely winning situation may become almost-surely losing if the player
    is only allowed to use a weaker notion of strategy. In more reasonable settings,
    translations exist, but they require infinite memory, even in simple cases. Finally,
    some traditional problems becomes undecidable for the strongest type of strategies.'
alternative_title:
- EPTCS
article_processing_charge: No
arxiv: 1
author:
- first_name: Julien
  full_name: Cristau, Julien
  last_name: Cristau
- first_name: Claire
  full_name: David, Claire
  last_name: David
- first_name: Florian
  full_name: Horn, Florian
  id: 37327ACE-F248-11E8-B48F-1D18A9856A87
  last_name: Horn
citation:
  ama: 'Cristau J, David C, Horn F. How do we remember the past in randomised strategies?
    In: <i>Proceedings of GandALF 2010</i>. Vol 25. Open Publishing Association; 2010:30-39.
    doi:<a href="https://doi.org/10.4204/EPTCS.25.7">10.4204/EPTCS.25.7</a>'
  apa: 'Cristau, J., David, C., &#38; Horn, F. (2010). How do we remember the past
    in randomised strategies? In <i>Proceedings of GandALF 2010</i> (Vol. 25, pp.
    30–39). Minori, Amalfi Coast, Italy: Open Publishing Association. <a href="https://doi.org/10.4204/EPTCS.25.7">https://doi.org/10.4204/EPTCS.25.7</a>'
  chicago: Cristau, Julien, Claire David, and Florian Horn. “How Do We Remember the
    Past in Randomised Strategies?” In <i>Proceedings of GandALF 2010</i>, 25:30–39.
    Open Publishing Association, 2010. <a href="https://doi.org/10.4204/EPTCS.25.7">https://doi.org/10.4204/EPTCS.25.7</a>.
  ieee: J. Cristau, C. David, and F. Horn, “How do we remember the past in randomised
    strategies?,” in <i>Proceedings of GandALF 2010</i>, Minori, Amalfi Coast, Italy,
    2010, vol. 25, pp. 30–39.
  ista: 'Cristau J, David C, Horn F. 2010. How do we remember the past in randomised
    strategies? Proceedings of GandALF 2010. GandALF: Games, Automata, Logic, and
    Formal Verification, EPTCS, vol. 25, 30–39.'
  mla: Cristau, Julien, et al. “How Do We Remember the Past in Randomised Strategies?”
    <i>Proceedings of GandALF 2010</i>, vol. 25, Open Publishing Association, 2010,
    pp. 30–39, doi:<a href="https://doi.org/10.4204/EPTCS.25.7">10.4204/EPTCS.25.7</a>.
  short: J. Cristau, C. David, F. Horn, in:, Proceedings of GandALF 2010, Open Publishing
    Association, 2010, pp. 30–39.
conference:
  end_date: 2010-06-18
  location: Minori, Amalfi Coast, Italy
  name: 'GandALF: Games, Automata, Logic, and Formal Verification'
  start_date: 2010-06-17
corr_author: '1'
date_created: 2018-12-11T11:46:45Z
date_published: 2010-06-09T00:00:00Z
date_updated: 2026-06-18T18:51:53Z
day: '09'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.4204/EPTCS.25.7
external_id:
  arxiv:
  - '1006.1404'
fulldoi: https://doi.org/10.4204/EPTCS.25.7
intvolume: '        25'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1006.1404
month: '06'
oa: 1
oa_version: Published Version
page: 30 - 39
publication: Proceedings of GandALF 2010
publication_status: published
publisher: Open Publishing Association
publist_id: '7332'
quality_controlled: '1'
scopus_import: '1'
status: public
title: How do we remember the past in randomised strategies?
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 25
year: '2010'
...
---
_id: '533'
abstract:
- lang: eng
  text: Any programming error that can be revealed before compiling a program saves
    precious time for the programmer. While integrated development environments already
    do a good job by detecting, e.g., data-flow abnormalities, current static analysis
    tools suffer from false positives (&quot;noise&quot;) or require strong user interaction.
    We propose to avoid this deficiency by defining a new class of errors. A program
    fragment is doomed if its execution will inevitably fail, regardless of which
    state it is started in. We use a formal verification method to identify such errors
    fully automatically and, most significantly, without producing noise. We report
    on experiments with a prototype tool.
article_processing_charge: No
author:
- first_name: Jochen
  full_name: Hoenicke, Jochen
  last_name: Hoenicke
- first_name: Kari
  full_name: Leino, Kari
  last_name: Leino
- first_name: Andreas
  full_name: Podelski, Andreas
  last_name: Podelski
- first_name: Martin
  full_name: Schäf, Martin
  last_name: Schäf
- first_name: Thomas
  full_name: Wies, Thomas
  id: 447BFB88-F248-11E8-B48F-1D18A9856A87
  last_name: Wies
citation:
  ama: Hoenicke J, Leino K, Podelski A, Schäf M, Wies T. Doomed program points. <i>Formal
    Methods in System Design</i>. 2010;37(2-3):171-199. doi:<a href="https://doi.org/10.1007/s10703-010-0102-0">10.1007/s10703-010-0102-0</a>
  apa: Hoenicke, J., Leino, K., Podelski, A., Schäf, M., &#38; Wies, T. (2010). Doomed
    program points. <i>Formal Methods in System Design</i>. Springer. <a href="https://doi.org/10.1007/s10703-010-0102-0">https://doi.org/10.1007/s10703-010-0102-0</a>
  chicago: Hoenicke, Jochen, Kari Leino, Andreas Podelski, Martin Schäf, and Thomas
    Wies. “Doomed Program Points.” <i>Formal Methods in System Design</i>. Springer,
    2010. <a href="https://doi.org/10.1007/s10703-010-0102-0">https://doi.org/10.1007/s10703-010-0102-0</a>.
  ieee: J. Hoenicke, K. Leino, A. Podelski, M. Schäf, and T. Wies, “Doomed program
    points,” <i>Formal Methods in System Design</i>, vol. 37, no. 2–3. Springer, pp.
    171–199, 2010.
  ista: Hoenicke J, Leino K, Podelski A, Schäf M, Wies T. 2010. Doomed program points.
    Formal Methods in System Design. 37(2–3), 171–199.
  mla: Hoenicke, Jochen, et al. “Doomed Program Points.” <i>Formal Methods in System
    Design</i>, vol. 37, no. 2–3, Springer, 2010, pp. 171–99, doi:<a href="https://doi.org/10.1007/s10703-010-0102-0">10.1007/s10703-010-0102-0</a>.
  short: J. Hoenicke, K. Leino, A. Podelski, M. Schäf, T. Wies, Formal Methods in
    System Design 37 (2010) 171–199.
corr_author: '1'
date_created: 2018-12-11T11:47:01Z
date_published: 2010-12-01T00:00:00Z
date_updated: 2025-09-30T09:48:58Z
day: '01'
department:
- _id: ToHe
doi: 10.1007/s10703-010-0102-0
external_id:
  isi:
  - '000286631700004'
fulldoi: https://doi.org/10.1007/s10703-010-0102-0
intvolume: '        37'
isi: 1
issue: 2-3
language:
- iso: eng
month: '12'
oa_version: None
page: 171 - 199
publication: Formal Methods in System Design
publication_status: published
publisher: Springer
publist_id: '7284'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Doomed program points
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 37
year: '2010'
...
---
_id: '5388'
abstract:
- lang: eng
  text: "We present an algorithmic method for the synthesis of concurrent programs
    that are optimal with respect to quantitative performance measures. The input
    consists of a sequential sketch, that is, a program that does not contain synchronization
    constructs, and of a parametric performance model that assigns costs to actions
    such as locking, context switching, and idling. The quantitative synthesis problem
    is to automatically introduce synchronization constructs into the sequential sketch
    so that both correctness is guaranteed and worst-case (or average-case) performance
    is optimized. Correctness is formalized as race freedom or linearizability.\r\n\r\nWe
    show that for worst-case performance, the problem can be modeled\r\nas a 2-player
    graph game with quantitative (limit-average) objectives, and\r\nfor average-case
    performance, as a 2 1/2 -player graph game (with probabilistic transitions). In
    both cases, the optimal correct program is derived from an optimal strategy in
    the corresponding quantitative game. We prove that the respective game problems
    are computationally expensive (NP-complete), and present several techniques that
    overcome the theoretical difficulty in cases of concurrent programs of practical
    interest.\r\n\r\nWe have implemented a prototype tool and used it for the automatic
    syn- thesis of programs that access a concurrent list. For certain parameter val-
    ues, our method automatically synthesizes various classical synchronization schemes
    for implementing a concurrent list, such as fine-grained locking or a lazy algorithm.
    For other parameter values, a new, hybrid synchronization style is synthesized,
    which uses both the lazy approach and coarse-grained locks (instead of standard
    fine-grained locks). The trade-off occurs because while fine-grained locking tends
    to decrease the cost that is due to waiting for locks, it increases cache size
    requirements."
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Pavol
  full_name: Cerny, Pavol
  id: 4DCBEFFE-F248-11E8-B48F-1D18A9856A87
  last_name: Cerny
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Arjun
  full_name: Radhakrishna, Arjun
  id: 3B51CAC4-F248-11E8-B48F-1D18A9856A87
  last_name: Radhakrishna
- first_name: Rohit
  full_name: Singh, Rohit
  last_name: Singh
citation:
  ama: Chatterjee K, Cerny P, Henzinger TA, Radhakrishna A, Singh R. <i>Quantitative
    Synthesis for Concurrent Programs</i>. IST Austria; 2010. doi:<a href="https://doi.org/10.15479/AT:IST-2010-0004">10.15479/AT:IST-2010-0004</a>
  apa: Chatterjee, K., Cerny, P., Henzinger, T. A., Radhakrishna, A., &#38; Singh,
    R. (2010). <i>Quantitative synthesis for concurrent programs</i>. IST Austria.
    <a href="https://doi.org/10.15479/AT:IST-2010-0004">https://doi.org/10.15479/AT:IST-2010-0004</a>
  chicago: Chatterjee, Krishnendu, Pavol Cerny, Thomas A Henzinger, Arjun Radhakrishna,
    and Rohit Singh. <i>Quantitative Synthesis for Concurrent Programs</i>. IST Austria,
    2010. <a href="https://doi.org/10.15479/AT:IST-2010-0004">https://doi.org/10.15479/AT:IST-2010-0004</a>.
  ieee: K. Chatterjee, P. Cerny, T. A. Henzinger, A. Radhakrishna, and R. Singh, <i>Quantitative
    synthesis for concurrent programs</i>. IST Austria, 2010.
  ista: Chatterjee K, Cerny P, Henzinger TA, Radhakrishna A, Singh R. 2010. Quantitative
    synthesis for concurrent programs, IST Austria, 17p.
  mla: Chatterjee, Krishnendu, et al. <i>Quantitative Synthesis for Concurrent Programs</i>.
    IST Austria, 2010, doi:<a href="https://doi.org/10.15479/AT:IST-2010-0004">10.15479/AT:IST-2010-0004</a>.
  short: K. Chatterjee, P. Cerny, T.A. Henzinger, A. Radhakrishna, R. Singh, Quantitative
    Synthesis for Concurrent Programs, IST Austria, 2010.
date_created: 2018-12-12T11:39:03Z
date_published: 2010-10-07T00:00:00Z
date_updated: 2025-04-15T08:12:00Z
day: '07'
ddc:
- '000'
- '005'
department:
- _id: KrCh
- _id: ToHe
doi: 10.15479/AT:IST-2010-0004
file:
- access_level: open_access
  checksum: da38782d2388a6fa32109d10bb9bad67
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T11:53:53Z
  date_updated: 2020-07-14T12:46:42Z
  file_id: '5515'
  file_name: IST-2010-0004_IST-2010-0004.pdf
  file_size: 429101
  relation: main_file
file_date_updated: 2020-07-14T12:46:42Z
fulldoi: https://doi.org/10.15479/AT:IST-2010-0004
has_accepted_license: '1'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
page: '17'
publication_identifier:
  issn:
  - 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '24'
related_material:
  record:
  - id: '3366'
    relation: later_version
    status: public
status: public
title: Quantitative synthesis for concurrent programs
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2010'
...
---
_id: '5389'
abstract:
- lang: eng
  text: Boolean notions of correctness are formalized by preorders on systems. Quantitative
    measures of correctness can be formalized by real-valued distance functions between
    systems, where the distance between implementation and specification provides
    a measure of “fit” or “desirability.” We extend the simulation preorder to the
    quantitative setting, by making each player of a simulation game pay a certain
    price for her choices. We use the resulting games with quantitative objectives
    to define three different simulation distances. The correctness distance measures
    how much the specification must be changed in order to be satisfied by the implementation.
    The coverage distance measures how much the im- plementation restricts the degrees
    of freedom offered by the specification. The robustness distance measures how
    much a system can deviate from the implementation description without violating
    the specification. We consider these distances for safety as well as liveness
    specifications. The distances can be computed in polynomial time for safety specifications,
    and for liveness specifications given by weak fairness constraints. We show that
    the distance functions satisfy the triangle inequality, that the distance between
    two systems does not increase under parallel composition with a third system,
    and that the distance between two systems can be bounded from above and below
    by distances between abstractions of the two systems. These properties suggest
    that our simulation distances provide an appropriate basis for a quantitative
    theory of discrete systems. We also demonstrate how the robustness distance can
    be used to measure how many transmission errors are tolerated by error correcting
    codes.
alternative_title:
- IST Austria Technical Report
author:
- first_name: Pavol
  full_name: Cerny, Pavol
  id: 4DCBEFFE-F248-11E8-B48F-1D18A9856A87
  last_name: Cerny
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Arjun
  full_name: Radhakrishna, Arjun
  id: 3B51CAC4-F248-11E8-B48F-1D18A9856A87
  last_name: Radhakrishna
citation:
  ama: Cerny P, Henzinger TA, Radhakrishna A. <i>Simulation Distances</i>. IST Austria;
    2010. doi:<a href="https://doi.org/10.15479/AT:IST-2010-0003">10.15479/AT:IST-2010-0003</a>
  apa: Cerny, P., Henzinger, T. A., &#38; Radhakrishna, A. (2010). <i>Simulation distances</i>.
    IST Austria. <a href="https://doi.org/10.15479/AT:IST-2010-0003">https://doi.org/10.15479/AT:IST-2010-0003</a>
  chicago: Cerny, Pavol, Thomas A Henzinger, and Arjun Radhakrishna. <i>Simulation
    Distances</i>. IST Austria, 2010. <a href="https://doi.org/10.15479/AT:IST-2010-0003">https://doi.org/10.15479/AT:IST-2010-0003</a>.
  ieee: P. Cerny, T. A. Henzinger, and A. Radhakrishna, <i>Simulation distances</i>.
    IST Austria, 2010.
  ista: Cerny P, Henzinger TA, Radhakrishna A. 2010. Simulation distances, IST Austria,
    24p.
  mla: Cerny, Pavol, et al. <i>Simulation Distances</i>. IST Austria, 2010, doi:<a
    href="https://doi.org/10.15479/AT:IST-2010-0003">10.15479/AT:IST-2010-0003</a>.
  short: P. Cerny, T.A. Henzinger, A. Radhakrishna, Simulation Distances, IST Austria,
    2010.
date_created: 2018-12-12T11:39:03Z
date_published: 2010-06-04T00:00:00Z
date_updated: 2026-06-18T18:41:23Z
day: '04'
ddc:
- '005'
department:
- _id: ToHe
doi: 10.15479/AT:IST-2010-0003
file:
- access_level: open_access
  checksum: 284ded99764e32a583a8ea83fcea254b
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T11:54:25Z
  date_updated: 2020-07-14T12:46:42Z
  file_id: '5547'
  file_name: IST-2010-0003_IST-2010-0003.pdf
  file_size: 367246
  relation: main_file
file_date_updated: 2020-07-14T12:46:42Z
fulldoi: https://doi.org/10.15479/AT:IST-2010-0003
has_accepted_license: '1'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: '24'
publication_identifier:
  issn:
  - 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '25'
related_material:
  record:
  - id: '4393'
    relation: later_version
    status: public
  - id: '3249'
    relation: later_version
    status: public
status: public
title: Simulation distances
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2010'
...
---
_id: '5390'
abstract:
- lang: eng
  text: The class of ω regular languages provide a robust specification language in
    verification. Every ω-regular condition can be decomposed into a safety part and
    a liveness part. The liveness part ensures that something good happens “eventually.”
    Two main strengths of the classical, infinite-limit formulation of liveness are
    robustness (independence from the granularity of transitions) and simplicity (abstraction
    of complicated time bounds). However, the classical liveness formulation suffers
    from the drawback that the time until something good happens may be unbounded.
    A stronger formulation of liveness, so-called finitary liveness, overcomes this
    drawback, while still retaining robustness and simplicity. Finitary liveness requires
    that there exists an unknown, fixed bound b such that something good happens within
    b transitions. In this work we consider the finitary parity and Streett (fairness)
    conditions. We present the topological, automata-theoretic and logical characterization
    of finitary languages defined by finitary parity and Streett conditions. We (a)
    show that the finitary parity and Streett languages are Σ2-complete; (b) present
    a complete characterization of the expressive power of various classes of automata
    with finitary and infinitary conditions (in particular we show that non-deterministic
    finitary parity and Streett automata cannot be determinized to deterministic finitary
    parity or Streett automata); and (c) show that the languages defined by non-deterministic
    finitary parity automata exactly characterize the star-free fragment of ωB-regular
    languages.
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Nathanaël
  full_name: Fijalkow, Nathanaël
  last_name: Fijalkow
citation:
  ama: Chatterjee K, Fijalkow N. <i>Topological, Automata-Theoretic and Logical Characterization
    of Finitary Languages</i>. IST Austria; 2010. doi:<a href="https://doi.org/10.15479/AT:IST-2010-0002">10.15479/AT:IST-2010-0002</a>
  apa: Chatterjee, K., &#38; Fijalkow, N. (2010). <i>Topological, automata-theoretic
    and logical characterization of finitary languages</i>. IST Austria. <a href="https://doi.org/10.15479/AT:IST-2010-0002">https://doi.org/10.15479/AT:IST-2010-0002</a>
  chicago: Chatterjee, Krishnendu, and Nathanaël Fijalkow. <i>Topological, Automata-Theoretic
    and Logical Characterization of Finitary Languages</i>. IST Austria, 2010. <a
    href="https://doi.org/10.15479/AT:IST-2010-0002">https://doi.org/10.15479/AT:IST-2010-0002</a>.
  ieee: K. Chatterjee and N. Fijalkow, <i>Topological, automata-theoretic and logical
    characterization of finitary languages</i>. IST Austria, 2010.
  ista: Chatterjee K, Fijalkow N. 2010. Topological, automata-theoretic and logical
    characterization of finitary languages, IST Austria, 21p.
  mla: Chatterjee, Krishnendu, and Nathanaël Fijalkow. <i>Topological, Automata-Theoretic
    and Logical Characterization of Finitary Languages</i>. IST Austria, 2010, doi:<a
    href="https://doi.org/10.15479/AT:IST-2010-0002">10.15479/AT:IST-2010-0002</a>.
  short: K. Chatterjee, N. Fijalkow, Topological, Automata-Theoretic and Logical Characterization
    of Finitary Languages, IST Austria, 2010.
date_created: 2018-12-12T11:39:03Z
date_published: 2010-06-04T00:00:00Z
date_updated: 2020-07-14T23:04:41Z
day: '04'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2010-0002
file:
- access_level: open_access
  checksum: 283d3604d76dd4d5161585d4c8625fbe
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T11:54:10Z
  date_updated: 2020-07-14T12:46:43Z
  file_id: '5532'
  file_name: IST-2010-0002_IST-2010-0002.pdf
  file_size: 395662
  relation: main_file
file_date_updated: 2020-07-14T12:46:43Z
fulldoi: https://doi.org/10.15479/AT:IST-2010-0002
has_accepted_license: '1'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: '21'
publication_identifier:
  issn:
  - 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '26'
status: public
title: Topological, automata-theoretic and logical characterization of finitary languages
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2010'
...
---
_id: '5391'
abstract:
- lang: eng
  text: Concurrent data structures with fine-grained synchronization are notoriously
    difficult to implement correctly. The difficulty of reasoning about these implementations
    does not stem from the number of variables or the program size, but rather from
    the large number of possible interleavings. These implementations are therefore
    prime candidates for model checking. We introduce an algorithm for verifying linearizability
    of singly-linked heap-based concurrent data structures. We consider a model consisting
    of an unbounded heap where each node consists an element from an unbounded data
    domain, with a restricted set of operations for testing and updating pointers
    and data elements. Our main result is that linearizability is decidable for programs
    that invoke a fixed number of methods, possibly in parallel. This decidable fragment
    covers many of the common implementation techniques — fine-grained locking, lazy
    synchronization, and lock-free synchronization. We also show how the technique
    can be used to verify optimistic implementations with the help of programmer annotations.
    We developed a verification tool CoLT and evaluated it on a representative sample
    of Java implementations of the concurrent set data structure. The tool verified
    linearizability of a number of implementations, found a known error in a lock-free
    imple- mentation and proved that the corrected version is linearizable.
alternative_title:
- IST Austria Technical Report
author:
- first_name: Pavol
  full_name: Cerny, Pavol
  id: 4DCBEFFE-F248-11E8-B48F-1D18A9856A87
  last_name: Cerny
- first_name: Arjun
  full_name: Radhakrishna, Arjun
  id: 3B51CAC4-F248-11E8-B48F-1D18A9856A87
  last_name: Radhakrishna
- first_name: Damien
  full_name: Zufferey, Damien
  id: 4397AC76-F248-11E8-B48F-1D18A9856A87
  last_name: Zufferey
  orcid: 0000-0002-3197-8736
- first_name: Swarat
  full_name: Chaudhuri, Swarat
  last_name: Chaudhuri
- first_name: Rajeev
  full_name: Alur, Rajeev
  last_name: Alur
citation:
  ama: Cerny P, Radhakrishna A, Zufferey D, Chaudhuri S, Alur R. <i>Model Checking
    of Linearizability of Concurrent List Implementations</i>. IST Austria; 2010.
    doi:<a href="https://doi.org/10.15479/AT:IST-2010-0001">10.15479/AT:IST-2010-0001</a>
  apa: Cerny, P., Radhakrishna, A., Zufferey, D., Chaudhuri, S., &#38; Alur, R. (2010).
    <i>Model checking of linearizability of concurrent list implementations</i>. IST
    Austria. <a href="https://doi.org/10.15479/AT:IST-2010-0001">https://doi.org/10.15479/AT:IST-2010-0001</a>
  chicago: Cerny, Pavol, Arjun Radhakrishna, Damien Zufferey, Swarat Chaudhuri, and
    Rajeev Alur. <i>Model Checking of Linearizability of Concurrent List Implementations</i>.
    IST Austria, 2010. <a href="https://doi.org/10.15479/AT:IST-2010-0001">https://doi.org/10.15479/AT:IST-2010-0001</a>.
  ieee: P. Cerny, A. Radhakrishna, D. Zufferey, S. Chaudhuri, and R. Alur, <i>Model
    checking of linearizability of concurrent list implementations</i>. IST Austria,
    2010.
  ista: Cerny P, Radhakrishna A, Zufferey D, Chaudhuri S, Alur R. 2010. Model checking
    of linearizability of concurrent list implementations, IST Austria, 27p.
  mla: Cerny, Pavol, et al. <i>Model Checking of Linearizability of Concurrent List
    Implementations</i>. IST Austria, 2010, doi:<a href="https://doi.org/10.15479/AT:IST-2010-0001">10.15479/AT:IST-2010-0001</a>.
  short: P. Cerny, A. Radhakrishna, D. Zufferey, S. Chaudhuri, R. Alur, Model Checking
    of Linearizability of Concurrent List Implementations, IST Austria, 2010.
date_created: 2018-12-12T11:39:04Z
date_published: 2010-04-19T00:00:00Z
date_updated: 2024-10-21T06:03:05Z
day: '19'
ddc:
- '004'
department:
- _id: ToHe
doi: 10.15479/AT:IST-2010-0001
file:
- access_level: open_access
  checksum: 986645caad7dd85a6a091488f6c646dc
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T11:53:44Z
  date_updated: 2020-07-14T12:46:43Z
  file_id: '5505'
  file_name: IST-2010-0001_IST-2010-0001.pdf
  file_size: 372286
  relation: main_file
file_date_updated: 2020-07-14T12:46:43Z
fulldoi: https://doi.org/10.15479/AT:IST-2010-0001
has_accepted_license: '1'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: '27'
publication_identifier:
  issn:
  - 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '27'
related_material:
  record:
  - id: '4390'
    relation: later_version
    status: public
status: public
title: Model checking of linearizability of concurrent list implementations
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2010'
...
---
_id: '5940'
article_processing_charge: No
author:
- first_name: Gabriel
  full_name: Juhás, Gabriel
  last_name: Juhás
- first_name: Igor
  full_name: Kazlov, Igor
  id: 4A997E50-F248-11E8-B48F-1D18A9856A87
  last_name: Kazlov
- first_name: Ana
  full_name: Juhásová, Ana
  last_name: Juhásová
citation:
  ama: 'Juhás G, Kazlov I, Juhásová A. Instance Deadlock: A Mystery behind Frozen
    Programs. In: <i>Applications and Theory of Petri Nets</i>. Berlin, Heidelberg:
    Springer Berlin Heidelberg; 2010:1-17. doi:<a href="https://doi.org/10.1007/978-3-642-13675-7_1">10.1007/978-3-642-13675-7_1</a>'
  apa: 'Juhás, G., Kazlov, I., &#38; Juhásová, A. (2010). Instance Deadlock: A Mystery
    behind Frozen Programs. In <i>Applications and Theory of Petri Nets</i> (pp. 1–17).
    Berlin, Heidelberg: Springer Berlin Heidelberg. <a href="https://doi.org/10.1007/978-3-642-13675-7_1">https://doi.org/10.1007/978-3-642-13675-7_1</a>'
  chicago: 'Juhás, Gabriel, Igor Kazlov, and Ana Juhásová. “Instance Deadlock: A Mystery
    behind Frozen Programs.” In <i>Applications and Theory of Petri Nets</i>, 1–17.
    Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. <a href="https://doi.org/10.1007/978-3-642-13675-7_1">https://doi.org/10.1007/978-3-642-13675-7_1</a>.'
  ieee: 'G. Juhás, I. Kazlov, and A. Juhásová, “Instance Deadlock: A Mystery behind
    Frozen Programs,” in <i>Applications and Theory of Petri Nets</i>, Berlin, Heidelberg:
    Springer Berlin Heidelberg, 2010, pp. 1–17.'
  ista: 'Juhás G, Kazlov I, Juhásová A. 2010.Instance Deadlock: A Mystery behind Frozen
    Programs. In: Applications and Theory of Petri Nets. , 1–17.'
  mla: 'Juhás, Gabriel, et al. “Instance Deadlock: A Mystery behind Frozen Programs.”
    <i>Applications and Theory of Petri Nets</i>, Springer Berlin Heidelberg, 2010,
    pp. 1–17, doi:<a href="https://doi.org/10.1007/978-3-642-13675-7_1">10.1007/978-3-642-13675-7_1</a>.'
  short: G. Juhás, I. Kazlov, A. Juhásová, in:, Applications and Theory of Petri Nets,
    Springer Berlin Heidelberg, Berlin, Heidelberg, 2010, pp. 1–17.
date_created: 2019-02-08T09:33:41Z
date_published: 2010-01-01T00:00:00Z
date_updated: 2022-04-01T13:45:24Z
doi: 10.1007/978-3-642-13675-7_1
extern: '1'
fulldoi: https://doi.org/10.1007/978-3-642-13675-7_1
language:
- iso: eng
oa_version: None
page: 1-17
place: Berlin, Heidelberg
publication: Applications and Theory of Petri Nets
publication_identifier:
  isbn:
  - '9783642136740'
  - '9783642136757'
  issn:
  - 0302-9743
  - 1611-3349
publication_status: published
publisher: Springer Berlin Heidelberg
status: public
title: 'Instance Deadlock: A Mystery behind Frozen Programs'
type: book_chapter
user_id: 4A997E50-F248-11E8-B48F-1D18A9856A87
year: '2010'
...
---
_id: '598'
abstract:
- lang: eng
  text: It is not well understood how the human Mediator complex, transcription factor
    IIH and RNA polymerase II (Pol II) work together with activators to initiate transcription.
    Activator binding alters Mediator structure, yet the functional consequences of
    such structural shifts remain unknown. The p53 C terminus and its activation domain
    interact with different Mediator subunits, and we find that each interaction differentially
    affects Mediator structure; strikingly, distinct p53-Mediator structures differentially
    affect Pol II activity. Only the p53 activation domain induces the formation of
    a large pocket domain at the Mediator-Pol II interaction site, and this correlates
    with activation of stalled Pol II to a productively elongating state. Moreover,
    we define a Mediator requirement for TFIIH-dependent Pol II C-terminal domain
    phosphorylation and identify substantial differences in Pol II C-terminal domain
    processing that correspond to distinct p53-Mediator structural states. Our results
    define a fundamental mechanism by which p53 activates transcription and suggest
    that Mediator structural shifts trigger activation of stalled Pol II complexes.
article_processing_charge: No
author:
- first_name: Krista
  full_name: Meyer, Krista
  last_name: Meyer
- first_name: Shih
  full_name: Lin, Shih
  last_name: Lin
- first_name: Carrie A
  full_name: Bernecky, Carrie A
  id: 2CB9DFE2-F248-11E8-B48F-1D18A9856A87
  last_name: Bernecky
  orcid: 0000-0003-0893-7036
- first_name: Yuefeng
  full_name: Gao, Yuefeng
  last_name: Gao
- first_name: Dylan
  full_name: Taatjes, Dylan
  last_name: Taatjes
citation:
  ama: Meyer K, Lin S, Bernecky C, Gao Y, Taatjes D. P53 activates transcription by
    directing structural shifts in Mediator. <i>Nature Structural and Molecular Biology</i>.
    2010;17(6):753-760. doi:<a href="https://doi.org/10.1038/nsmb.1816">10.1038/nsmb.1816</a>
  apa: Meyer, K., Lin, S., Bernecky, C., Gao, Y., &#38; Taatjes, D. (2010). P53 activates
    transcription by directing structural shifts in Mediator. <i>Nature Structural
    and Molecular Biology</i>. Nature Publishing Group. <a href="https://doi.org/10.1038/nsmb.1816">https://doi.org/10.1038/nsmb.1816</a>
  chicago: Meyer, Krista, Shih Lin, Carrie Bernecky, Yuefeng Gao, and Dylan Taatjes.
    “P53 Activates Transcription by Directing Structural Shifts in Mediator.” <i>Nature
    Structural and Molecular Biology</i>. Nature Publishing Group, 2010. <a href="https://doi.org/10.1038/nsmb.1816">https://doi.org/10.1038/nsmb.1816</a>.
  ieee: K. Meyer, S. Lin, C. Bernecky, Y. Gao, and D. Taatjes, “P53 activates transcription
    by directing structural shifts in Mediator,” <i>Nature Structural and Molecular
    Biology</i>, vol. 17, no. 6. Nature Publishing Group, pp. 753–760, 2010.
  ista: Meyer K, Lin S, Bernecky C, Gao Y, Taatjes D. 2010. P53 activates transcription
    by directing structural shifts in Mediator. Nature Structural and Molecular Biology.
    17(6), 753–760.
  mla: Meyer, Krista, et al. “P53 Activates Transcription by Directing Structural
    Shifts in Mediator.” <i>Nature Structural and Molecular Biology</i>, vol. 17,
    no. 6, Nature Publishing Group, 2010, pp. 753–60, doi:<a href="https://doi.org/10.1038/nsmb.1816">10.1038/nsmb.1816</a>.
  short: K. Meyer, S. Lin, C. Bernecky, Y. Gao, D. Taatjes, Nature Structural and
    Molecular Biology 17 (2010) 753–760.
date_created: 2018-12-11T11:47:24Z
date_published: 2010-06-01T00:00:00Z
date_updated: 2021-01-12T08:05:28Z
day: '01'
doi: 10.1038/nsmb.1816
extern: '1'
fulldoi: https://doi.org/10.1038/nsmb.1816
intvolume: '        17'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932482/
month: '06'
oa: 1
oa_version: None
page: 753 - 760
publication: Nature Structural and Molecular Biology
publication_status: published
publisher: Nature Publishing Group
publist_id: '7210'
status: public
title: P53 activates transcription by directing structural shifts in Mediator
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2010'
...
---
_id: '6142'
abstract:
- lang: eng
  text: Defining the mutational landscape when individuals of a species grow separately
    and diverge over many generations can provide insights into trait evolution. A
    specific example of this involves studying changes associated with domestication
    where different lines of the same wild stock have been cultivated independently
    in different standard environments. Whole genome sequence comparison of such lines
    permits estimation of mutation rates, inference of genes' ancestral states and
    ancestry of existing strains, and correction of sequencing errors in genome databases.
    Here we study domestication of the C. elegans Bristol strain as a model, and report
    the genome sequence of LSJ1 (Bristol), a sibling of the standard C. elegans reference
    wild type N2 (Bristol). The LSJ1 and N2 lines were cultivated separately from
    shortly after the Bristol strain was isolated until methods to freeze C. elegans
    were developed. We find that during this time the two strains have accumulated
    1208 genetic differences. We describe phenotypic variation between N2 and LSJ1
    in the rate at which embryos develop, the rate of production of eggs, the maturity
    of eggs at laying, and feeding behavior, all the result of post-isolation changes.
    We infer the ancestral alleles in the original Bristol isolate and highlight 2038
    likely sequencing errors in the original N2 reference genome sequence. Many of
    these changes modify genome annotation. Our study provides a starting point to
    further investigate genotype-phenotype association and offers insights into the
    process of selection as a result of laboratory domestication.
article_number: e13922
author:
- first_name: Katherine P.
  full_name: Weber, Katherine P.
  last_name: Weber
- first_name: Subhajyoti
  full_name: De, Subhajyoti
  last_name: De
- first_name: Iwanka
  full_name: Kozarewa, Iwanka
  last_name: Kozarewa
- first_name: Daniel J.
  full_name: Turner, Daniel J.
  last_name: Turner
- first_name: M. Madan
  full_name: Babu, M. Madan
  last_name: Babu
- first_name: Mario
  full_name: de Bono, Mario
  id: 4E3FF80E-F248-11E8-B48F-1D18A9856A87
  last_name: de Bono
  orcid: 0000-0001-8347-0443
citation:
  ama: Weber KP, De S, Kozarewa I, Turner DJ, Babu MM, de Bono M. Whole genome sequencing
    highlights genetic changes associated with laboratory domestication of C. elegans.
    <i>PLoS ONE</i>. 2010;5(11). doi:<a href="https://doi.org/10.1371/journal.pone.0013922">10.1371/journal.pone.0013922</a>
  apa: Weber, K. P., De, S., Kozarewa, I., Turner, D. J., Babu, M. M., &#38; de Bono,
    M. (2010). Whole genome sequencing highlights genetic changes associated with
    laboratory domestication of C. elegans. <i>PLoS ONE</i>. Public Library of Science.
    <a href="https://doi.org/10.1371/journal.pone.0013922">https://doi.org/10.1371/journal.pone.0013922</a>
  chicago: Weber, Katherine P., Subhajyoti De, Iwanka Kozarewa, Daniel J. Turner,
    M. Madan Babu, and Mario de Bono. “Whole Genome Sequencing Highlights Genetic
    Changes Associated with Laboratory Domestication of C. Elegans.” <i>PLoS ONE</i>.
    Public Library of Science, 2010. <a href="https://doi.org/10.1371/journal.pone.0013922">https://doi.org/10.1371/journal.pone.0013922</a>.
  ieee: K. P. Weber, S. De, I. Kozarewa, D. J. Turner, M. M. Babu, and M. de Bono,
    “Whole genome sequencing highlights genetic changes associated with laboratory
    domestication of C. elegans,” <i>PLoS ONE</i>, vol. 5, no. 11. Public Library
    of Science, 2010.
  ista: Weber KP, De S, Kozarewa I, Turner DJ, Babu MM, de Bono M. 2010. Whole genome
    sequencing highlights genetic changes associated with laboratory domestication
    of C. elegans. PLoS ONE. 5(11), e13922.
  mla: Weber, Katherine P., et al. “Whole Genome Sequencing Highlights Genetic Changes
    Associated with Laboratory Domestication of C. Elegans.” <i>PLoS ONE</i>, vol.
    5, no. 11, e13922, Public Library of Science, 2010, doi:<a href="https://doi.org/10.1371/journal.pone.0013922">10.1371/journal.pone.0013922</a>.
  short: K.P. Weber, S. De, I. Kozarewa, D.J. Turner, M.M. Babu, M. de Bono, PLoS
    ONE 5 (2010).
date_created: 2019-03-20T15:20:30Z
date_published: 2010-11-11T00:00:00Z
date_updated: 2021-01-12T08:06:20Z
day: '11'
ddc:
- '570'
doi: 10.1371/journal.pone.0013922
extern: '1'
external_id:
  pmid:
  - '21085631'
file:
- access_level: open_access
  checksum: a01e6bbe15f044c0c79a26d7d881953e
  content_type: application/pdf
  creator: kschuh
  date_created: 2019-03-20T15:22:48Z
  date_updated: 2020-07-14T12:47:20Z
  file_id: '6143'
  file_name: 2010_PLOS_Weber.PDF
  file_size: 578059
  relation: main_file
file_date_updated: 2020-07-14T12:47:20Z
fulldoi: https://doi.org/10.1371/journal.pone.0013922
has_accepted_license: '1'
intvolume: '         5'
issue: '11'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
pmid: 1
publication: PLoS ONE
publication_identifier:
  issn:
  - 1932-6203
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
status: public
title: Whole genome sequencing highlights genetic changes associated with laboratory
  domestication of C. elegans
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2010'
...
---
_id: '619'
abstract:
- lang: eng
  text: Sinclair Ross’s novel As for Me and My House has long since been canonized
    as Canadian prairie fiction. Accordingly, it has been the subject of many critical
    studies and academic papers. Most commentators have concentrated on such literary
    issues as the representation of the western landscape or the reliability of the
    female narrator. But so far little consideration has been given to the social
    and cultural implications of the novel. Few attempts have been made to analyze
    the text from a cultural perspective including such social markers as class, gender
    and ethnicity. That is all the more surprising because Sinclair Ross has often
    been credited for being a realistic author and As for Me and My House has often
    been interpreted as a regional novel characteristic of a particular time and place.
author:
- first_name: Waldemar
  full_name: Zacharasiewicz, Waldemar
  last_name: Zacharasiewicz
- first_name: Fritz
  full_name: Kirsch, Fritz Peter
  last_name: Kirsch
citation:
  ama: 'Zacharasiewicz W, Kirsch F. “This is a fundamentalist town”: The Prairie Town
    as a Site of Social and Cultural Conflict in Sinclair Ross’s As for Me and My
    House. In: <i>Social and Cultural Interaction and Literary Landscapes in the Canadian
    West : Impressions of an Exploratory Field Trip and Academic Interaction in the
    Canadian West : Rapports Interculturels et Paysages Littéraires Dans l’Ouest Canadien</i>.
    Facultas.WUV; 2010:173-179.'
  apa: 'Zacharasiewicz, W., &#38; Kirsch, F. (2010). “This is a fundamentalist town”:
    The Prairie Town as a Site of Social and Cultural Conflict in Sinclair Ross’s
    As for Me and My House. In <i>Social and cultural interaction and literary landscapes
    in the Canadian West : impressions of an exploratory field trip and academic interaction
    in the Canadian West : Rapports interculturels et paysages littéraires dans l’Ouest
    canadien</i> (pp. 173–179). Facultas.WUV.'
  chicago: 'Zacharasiewicz, Waldemar, and Fritz Kirsch. “‘This Is a Fundamentalist
    Town’: The Prairie Town as a Site of Social and Cultural Conflict in Sinclair
    Ross’s As for Me and My House.” In <i>Social and Cultural Interaction and Literary
    Landscapes in the Canadian West : Impressions of an Exploratory Field Trip and
    Academic Interaction in the Canadian West : Rapports Interculturels et Paysages
    Littéraires Dans l’Ouest Canadien</i>, 173–79. Facultas.WUV, 2010.'
  ieee: 'W. Zacharasiewicz and F. Kirsch, “‘This is a fundamentalist town’: The Prairie
    Town as a Site of Social and Cultural Conflict in Sinclair Ross’s As for Me and
    My House,” in <i>Social and cultural interaction and literary landscapes in the
    Canadian West : impressions of an exploratory field trip and academic interaction
    in the Canadian West : Rapports interculturels et paysages littéraires dans l’Ouest
    canadien</i>, Facultas.WUV, 2010, pp. 173–179.'
  ista: 'Zacharasiewicz W, Kirsch F. 2010.“This is a fundamentalist town”: The Prairie
    Town as a Site of Social and Cultural Conflict in Sinclair Ross’s As for Me and
    My House. In: Social and cultural interaction and literary landscapes in the Canadian
    West : impressions of an exploratory field trip and academic interaction in the
    Canadian West : Rapports interculturels et paysages littéraires dans l’Ouest canadien.
    , 173–179.'
  mla: 'Zacharasiewicz, Waldemar, and Fritz Kirsch. “‘This Is a Fundamentalist Town’:
    The Prairie Town as a Site of Social and Cultural Conflict in Sinclair Ross’s
    As for Me and My House.” <i>Social and Cultural Interaction and Literary Landscapes
    in the Canadian West : Impressions of an Exploratory Field Trip and Academic Interaction
    in the Canadian West : Rapports Interculturels et Paysages Littéraires Dans l’Ouest
    Canadien</i>, Facultas.WUV, 2010, pp. 173–79.'
  short: 'W. Zacharasiewicz, F. Kirsch, in:, Social and Cultural Interaction and Literary
    Landscapes in the Canadian West : Impressions of an Exploratory Field Trip and
    Academic Interaction in the Canadian West : Rapports Interculturels et Paysages
    Littéraires Dans l’Ouest Canadien, Facultas.WUV, 2010, pp. 173–179.'
date_created: 2018-12-11T11:47:32Z
date_published: 2010-01-01T00:00:00Z
date_updated: 2021-01-12T08:06:40Z
day: '01'
extern: 1
month: '01'
page: 173 - 179
publication: 'Social and cultural interaction and literary landscapes in the Canadian
  West : impressions of an exploratory field trip and academic interaction in the
  Canadian West : Rapports interculturels et paysages littéraires dans l''Ouest canadien'
publication_status: published
publisher: Facultas.WUV
publist_id: '7185'
quality_controlled: 0
status: public
title: '“This is a fundamentalist town”: The Prairie Town as a Site of Social and
  Cultural Conflict in Sinclair Ross’s As for Me and My House'
type: book_chapter
year: '2010'
...
---
_id: '6198'
abstract:
- lang: eng
  text: 'Stroke is a major public health problem leading to high rates of death and
    disability in adults. Excessive stimulation of N-methyl-D-aspartate receptors
    (NMDARs) and the resulting neuronal nitric oxide synthase (nNOS) activation are
    crucial for neuronal injury after stroke insult. However, directly inhibiting
    NMDARs or nNOS can cause severe side effects because they have key physiological
    functions in the CNS. Here we show that cerebral ischemia induces the interaction
    of nNOS with postsynaptic density protein-95 (PSD-95). Disrupting nNOS-PSD-95
    interaction via overexpressing the N-terminal amino acid residues 1-133 of nNOS
    (nNOS-N(1-133)) prevented glutamate-induced excitotoxicity and cerebral ischemic
    damage. Given the mechanism of nNOS-PSD-95 interaction, we developed a series
    of compounds and discovered a small-molecular inhibitor of the nNOS-PSD-95 interaction,
    ZL006. This drug blocked the ischemia-induced nNOS-PSD-95 association selectively,
    had potent neuroprotective activity in vitro and ameliorated focal cerebral ischemic
    damage in mice and rats subjected to middle cerebral artery occlusion (MCAO) and
    reperfusion. Moreover, it readily crossed the blood-brain barrier, did not inhibit
    NMDAR function, catalytic activity of nNOS or spatial memory, and had no effect
    on aggressive behaviors. Thus, this new drug may serve as a treatment for stroke,
    perhaps without major side effects. '
author:
- first_name: L
  full_name: Zhou, L
  last_name: Zhou
- first_name: F
  full_name: Li, F
  last_name: Li
- first_name: Haibing
  full_name: Xu, Haibing
  id: 310349D0-F248-11E8-B48F-1D18A9856A87
  last_name: Xu
- first_name: CX
  full_name: Luo, CX
  last_name: Luo
- first_name: HY
  full_name: Wu, HY
  last_name: Wu
- first_name: MM
  full_name: Zhu, MM
  last_name: Zhu
- first_name: W
  full_name: Lu, W
  last_name: Lu
- first_name: X
  full_name: Ji, X
  last_name: Ji
- first_name: QG
  full_name: Zhou, QG
  last_name: Zhou
- first_name: DY
  full_name: Zhu, DY
  last_name: Zhu
citation:
  ama: Zhou L, Li F, Xu H, et al. Treatment of cerebral ischemia by disrupting ischemia-induced
    interaction of nNOS with PSD-95. <i>Nature Medicine</i>. 2010;16(12):1439-1443.
    doi:<a href="https://doi.org/10.1038/nm.2245">10.1038/nm.2245</a>
  apa: Zhou, L., Li, F., Xu, H., Luo, C., Wu, H., Zhu, M., … Zhu, D. (2010). Treatment
    of cerebral ischemia by disrupting ischemia-induced interaction of nNOS with PSD-95.
    <i>Nature Medicine</i>. Nature Publishing Group. <a href="https://doi.org/10.1038/nm.2245">https://doi.org/10.1038/nm.2245</a>
  chicago: Zhou, L, F Li, Haibing Xu, CX Luo, HY Wu, MM Zhu, W Lu, X Ji, QG Zhou,
    and DY Zhu. “Treatment of Cerebral Ischemia by Disrupting Ischemia-Induced Interaction
    of NNOS with PSD-95.” <i>Nature Medicine</i>. Nature Publishing Group, 2010. <a
    href="https://doi.org/10.1038/nm.2245">https://doi.org/10.1038/nm.2245</a>.
  ieee: L. Zhou <i>et al.</i>, “Treatment of cerebral ischemia by disrupting ischemia-induced
    interaction of nNOS with PSD-95,” <i>Nature Medicine</i>, vol. 16, no. 12. Nature
    Publishing Group, pp. 1439–1443, 2010.
  ista: Zhou L, Li F, Xu H, Luo C, Wu H, Zhu M, Lu W, Ji X, Zhou Q, Zhu D. 2010. Treatment
    of cerebral ischemia by disrupting ischemia-induced interaction of nNOS with PSD-95.
    Nature Medicine. 16(12), 1439–1443.
  mla: Zhou, L., et al. “Treatment of Cerebral Ischemia by Disrupting Ischemia-Induced
    Interaction of NNOS with PSD-95.” <i>Nature Medicine</i>, vol. 16, no. 12, Nature
    Publishing Group, 2010, pp. 1439–43, doi:<a href="https://doi.org/10.1038/nm.2245">10.1038/nm.2245</a>.
  short: L. Zhou, F. Li, H. Xu, C. Luo, H. Wu, M. Zhu, W. Lu, X. Ji, Q. Zhou, D. Zhu,
    Nature Medicine 16 (2010) 1439–1443.
date_created: 2019-04-04T14:55:32Z
date_published: 2010-11-21T00:00:00Z
date_updated: 2021-01-12T08:06:43Z
day: '21'
doi: 10.1038/nm.2245
extern: '1'
external_id:
  pmid:
  - '21102461'
fulldoi: https://doi.org/10.1038/nm.2245
intvolume: '        16'
issue: '12'
language:
- iso: eng
month: '11'
oa_version: None
page: 1439-1443
pmid: 1
publication: Nature Medicine
publication_identifier:
  issn:
  - 1078-8956
  - 1546-170x
publication_status: published
publisher: Nature Publishing Group
quality_controlled: '1'
status: public
title: Treatment of cerebral ischemia by disrupting ischemia-induced interaction of
  nNOS with PSD-95
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 16
year: '2010'
...
---
_id: '2071'
abstract:
- lang: eng
  text: The X or Z chromosome has several characteristics that distinguish it from
    the autosomes, namely hemizygosity in the heterogametic sex, and a potentially
    different effective population size, both of which may influence the rate and
    nature of evolution. In particular, there may be an accelerated rate of adaptive
    change for X-linked compared to autosomal coding sequences, often referred to
    as the Faster-X effect. Empirical studies have indicated that the strength of
    Faster-X evolution varies among different species, and theoretical treatments
    have shown that demography and mating system can substantially affect the degree
    of Faster-X evolution. Here we integrate genomic data on Faster-X evolution from
    a variety of animals with the demographic factors, mating system, and sex chromosome
    regulatory characteristics that may influence it. Our results suggest that differences
    in effective population size and mechanisms of dosage compensation may influence
    the perceived extent of Faster-X evolution, and help to explain several clade-specific
    patterns that we observe.
acknowledgement: We gratefully acknowledge funding from the Royal Society (to JEM)
author:
- first_name: Judith
  full_name: Mank, Judith E
  last_name: Mank
- first_name: Beatriz
  full_name: Beatriz Vicoso
  id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
  last_name: Vicoso
  orcid: 0000-0002-4579-8306
- first_name: Sofia
  full_name: Berlin, Sofia
  last_name: Berlin
- first_name: Brian
  full_name: Charlesworth, Brian
  last_name: Charlesworth
citation:
  ama: 'Mank J, Vicoso B, Berlin S, Charlesworth B. Effective population size and
    the Faster-X effect: Empirical results and their interpretation. <i>Evolution</i>.
    2010;64(3):663-674. doi:<a href="https://doi.org/10.1111/j.1558-5646.2009.00853.x">10.1111/j.1558-5646.2009.00853.x</a>'
  apa: 'Mank, J., Vicoso, B., Berlin, S., &#38; Charlesworth, B. (2010). Effective
    population size and the Faster-X effect: Empirical results and their interpretation.
    <i>Evolution</i>. Wiley-Blackwell. <a href="https://doi.org/10.1111/j.1558-5646.2009.00853.x">https://doi.org/10.1111/j.1558-5646.2009.00853.x</a>'
  chicago: 'Mank, Judith, Beatriz Vicoso, Sofia Berlin, and Brian Charlesworth. “Effective
    Population Size and the Faster-X Effect: Empirical Results and Their Interpretation.”
    <i>Evolution</i>. Wiley-Blackwell, 2010. <a href="https://doi.org/10.1111/j.1558-5646.2009.00853.x">https://doi.org/10.1111/j.1558-5646.2009.00853.x</a>.'
  ieee: 'J. Mank, B. Vicoso, S. Berlin, and B. Charlesworth, “Effective population
    size and the Faster-X effect: Empirical results and their interpretation,” <i>Evolution</i>,
    vol. 64, no. 3. Wiley-Blackwell, pp. 663–674, 2010.'
  ista: 'Mank J, Vicoso B, Berlin S, Charlesworth B. 2010. Effective population size
    and the Faster-X effect: Empirical results and their interpretation. Evolution.
    64(3), 663–674.'
  mla: 'Mank, Judith, et al. “Effective Population Size and the Faster-X Effect: Empirical
    Results and Their Interpretation.” <i>Evolution</i>, vol. 64, no. 3, Wiley-Blackwell,
    2010, pp. 663–74, doi:<a href="https://doi.org/10.1111/j.1558-5646.2009.00853.x">10.1111/j.1558-5646.2009.00853.x</a>.'
  short: J. Mank, B. Vicoso, S. Berlin, B. Charlesworth, Evolution 64 (2010) 663–674.
date_created: 2018-12-11T11:55:32Z
date_published: 2010-03-01T00:00:00Z
date_updated: 2021-01-12T06:55:07Z
day: '01'
doi: 10.1111/j.1558-5646.2009.00853.x
extern: 1
fulldoi: https://doi.org/10.1111/j.1558-5646.2009.00853.x
intvolume: '        64'
issue: '3'
month: '03'
page: 663 - 674
publication: Evolution
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4967'
quality_controlled: 0
status: public
title: 'Effective population size and the Faster-X effect: Empirical results and their
  interpretation'
type: journal_article
volume: 64
year: '2010'
...
---
_id: '2075'
abstract:
- lang: eng
  text: "This thesis investigates the combination of data-driven and physically based
    techniques for acquiring, modeling, and animating deformable materials, with a
    special focus on human faces. Furthermore, based on these techniques, we introduce
    a data-driven process for designing and fabricating materials with desired deformation
    behavior. \nRealistic simulation behavior, surface details, and appearance are
    still demanding tasks. Neither pure data-driven, pure procedural, nor pure physical
    methods are best suited for accurate synthesis of facial motion and details (both
    for appearance and geometry), due to the difficulties in model design, parameter
    estimation, and desired controllability for animators. Capturing of a small but
    representative amount of real data, and then synthesizing diverse on-demand examples
    with physically-based models and real data as input benefits from both sides:
    Highly realistic model behavior due to real-world data and controllability due
    to physically-based models.\nTo model the face and its behavior, hybrid physically-based
    and data-driven approaches are elaborated. We investigate surface-based representations
    as well as a solid representation based on FEM. To achieve realistic behavior,
    we propose to build light-weighted data capture devices to acquire real-world
    data to estimate model parameters and to employ concepts from data-driven modeling
    techniques and machine learning. The resulting models support simple acquisition
    systems, offer techniques to process and extract model parameters from real-world
    data, provide a compact representation of the facial geometry and its motion,
    and allow intuitive editing. We demonstrate applications such as capture of facial
    geometry and motion and real-time animation and transfer of facial details, and
    show that our soft tissue model can react to external forces and produce realistic
    deformations beyond facial expressions.\nBased on this model, we furthermore introduce
    a data-driven process for designing and fabricating materials with desired deformation
    behavior. The process starts with measuring deformation properties of base materials.
    Each material is represented as a non-linear stress-strain relationship in a finite-element
    model. For material design and fabrication, we introduce an optimization process
    that finds the best combination of base materials that meets a user’s criteria
    specified by example deformations. Our algorithm employs a number of strategies
    to prune poor solutions from the combinatorial search space. We finally demonstrate
    the complete process by designing and fabricating objects with complex heterogeneous
    materials using modern multi-material 3D printers.\n"
author:
- first_name: Bernd
  full_name: Bernd Bickel
  id: 49876194-F248-11E8-B48F-1D18A9856A87
  last_name: Bickel
  orcid: 0000-0001-6511-9385
citation:
  ama: Bickel B. Measurement-based modeling and fabrication of deformable materials
    for human faces. <i>Unknown</i>. 2010;499(7458). doi:<a href="https://doi.org/dx.doi.org/10.3929/ethz-a-006354908">dx.doi.org/10.3929/ethz-a-006354908</a>
  apa: Bickel, B. (2010). <i>Measurement-based modeling and fabrication of deformable
    materials for human faces</i>. <i>Unknown</i>. Unknown. <a href="https://doi.org/dx.doi.org/10.3929/ethz-a-006354908">https://doi.org/dx.doi.org/10.3929/ethz-a-006354908</a>
  chicago: Bickel, Bernd. “Measurement-Based Modeling and Fabrication of Deformable
    Materials for Human Faces.” <i>Unknown</i>. Unknown, 2010. <a href="https://doi.org/dx.doi.org/10.3929/ethz-a-006354908">https://doi.org/dx.doi.org/10.3929/ethz-a-006354908</a>.
  ieee: B. Bickel, “Measurement-based modeling and fabrication of deformable materials
    for human faces,” Unknown, 2010.
  ista: Bickel B. 2010. Measurement-based modeling and fabrication of deformable materials
    for human faces. Unknown.
  mla: Bickel, Bernd. “Measurement-Based Modeling and Fabrication of Deformable Materials
    for Human Faces.” <i>Unknown</i>, vol. 499, no. 7458, Unknown, 2010, doi:<a href="https://doi.org/dx.doi.org/10.3929/ethz-a-006354908">dx.doi.org/10.3929/ethz-a-006354908</a>.
  short: B. Bickel, Measurement-Based Modeling and Fabrication of Deformable Materials
    for Human Faces, Unknown, 2010.
date_created: 2018-12-11T11:55:34Z
date_published: 2010-01-01T00:00:00Z
date_updated: 2021-01-12T06:55:09Z
day: '01'
doi: dx.doi.org/10.3929/ethz-a-006354908
extern: 1
fulldoi: https://doi.org/dx.doi.org/10.3929/ethz-a-006354908
intvolume: '       499'
issue: '7458'
month: '01'
publication: Unknown
publication_status: published
publisher: Unknown
publist_id: '4963'
quality_controlled: 0
status: public
title: Measurement-based modeling and fabrication of deformable materials for human
  faces
type: dissertation
volume: 499
year: '2010'
...
---
_id: '10127'
abstract:
- lang: eng
  text: We use numerical simulations to show how noninteracting hard particles binding
    to a deformable elastic shell may self-assemble into a variety of linear patterns.
    This is a result of the nontrivial elastic response to deformations of shells.
    The morphology of the patterns can be controlled by the mechanical properties
    of the surface, and can be fine-tuned by varying the binding energy of the particles.
    We also repeat our calculations for a fully flexible chain and find that the chain
    conformations follow patterns similar to those formed by the nanoparticles under
    analogous conditions. We propose a simple way of understanding and sorting the
    different structures and relate it to the underlying shape transition of the shell.
    Finally, we discuss the implications of our results.
acknowledgement: This work was supported by the National Science Foundation under
  Career Grant No. DMR-0846426. We thank Josep C. Pàmies for helpful discussions.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Anđela
  full_name: Šarić, Anđela
  id: bf63d406-f056-11eb-b41d-f263a6566d8b
  last_name: Šarić
  orcid: 0000-0002-7854-2139
- first_name: Angelo
  full_name: Cacciuto, Angelo
  last_name: Cacciuto
citation:
  ama: Šarić A, Cacciuto A. Particle self-assembly on soft elastic shells. <i>Soft
    Matter</i>. 2010;7(5):1874-1878. doi:<a href="https://doi.org/10.1039/c0sm01143f">10.1039/c0sm01143f</a>
  apa: Šarić, A., &#38; Cacciuto, A. (2010). Particle self-assembly on soft elastic
    shells. <i>Soft Matter</i>. Royal Society of Chemistry (RSC). <a href="https://doi.org/10.1039/c0sm01143f">https://doi.org/10.1039/c0sm01143f</a>
  chicago: Šarić, Anđela, and Angelo Cacciuto. “Particle Self-Assembly on Soft Elastic
    Shells.” <i>Soft Matter</i>. Royal Society of Chemistry (RSC), 2010. <a href="https://doi.org/10.1039/c0sm01143f">https://doi.org/10.1039/c0sm01143f</a>.
  ieee: A. Šarić and A. Cacciuto, “Particle self-assembly on soft elastic shells,”
    <i>Soft Matter</i>, vol. 7, no. 5. Royal Society of Chemistry (RSC), pp. 1874–1878,
    2010.
  ista: Šarić A, Cacciuto A. 2010. Particle self-assembly on soft elastic shells.
    Soft Matter. 7(5), 1874–1878.
  mla: Šarić, Anđela, and Angelo Cacciuto. “Particle Self-Assembly on Soft Elastic
    Shells.” <i>Soft Matter</i>, vol. 7, no. 5, Royal Society of Chemistry (RSC),
    2010, pp. 1874–78, doi:<a href="https://doi.org/10.1039/c0sm01143f">10.1039/c0sm01143f</a>.
  short: A. Šarić, A. Cacciuto, Soft Matter 7 (2010) 1874–1878.
date_created: 2021-10-12T08:34:23Z
date_published: 2010-12-23T00:00:00Z
date_updated: 2021-10-12T09:49:27Z
day: '23'
doi: 10.1039/c0sm01143f
extern: '1'
external_id:
  arxiv:
  - '1010.2453'
fulldoi: https://doi.org/10.1039/c0sm01143f
intvolume: '         7'
issue: '5'
keyword:
- condensed matter physics
- general chemistry
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1010.2453
month: '12'
oa: 1
oa_version: Preprint
page: 1874-1878
publication: Soft Matter
publication_identifier:
  issn:
  - 1744-683X
  - 1744-6848
publication_status: published
publisher: Royal Society of Chemistry (RSC)
quality_controlled: '1'
status: public
title: Particle self-assembly on soft elastic shells
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 7
year: '2010'
...
