---
_id: '3559'
abstract:
- lang: eng
text: Persistent homology is the mathematical core of recent work on shape, including
reconstruction, recognition, and matching. Its per- tinent information is encapsulated
by a pairing of the critical values of a function, visualized by points forming
a diagram in the plane. The original algorithm in [10] computes the pairs from
an ordering of the simplices in a triangulation and takes worst-case time cubic
in the number of simplices. The main result of this paper is an algorithm that
maintains the pairing in worst-case linear time per transposition in the ordering.
A side-effect of the algorithm’s anal- ysis is an elementary proof of the stability
of persistence diagrams [7] in the special case of piecewise-linear functions.
We use the algorithm to compute 1-parameter families of diagrams which we apply
to the study of protein folding trajectories.
acknowledgement: Partially supported by NSF under grant CCR- 00-86013, by DARPA under
grant HR0011-05-1-0007, and by the Lawrence Livermore National Laboratory under
grant B543154.
author:
- first_name: David
full_name: Cohen-Steiner, David
last_name: Cohen Steiner
- first_name: Herbert
full_name: Herbert Edelsbrunner
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Dmitriy
full_name: Morozov, Dmitriy
last_name: Morozov
citation:
ama: 'Cohen Steiner D, Edelsbrunner H, Morozov D. Vines and vineyards by updating
persistence in linear time. In: ACM; 2006:119-126. doi:10.1145/1137856.1137877'
apa: 'Cohen Steiner, D., Edelsbrunner, H., & Morozov, D. (2006). Vines and vineyards
by updating persistence in linear time (pp. 119–126). Presented at the SCG: Symposium
on Computational Geometry, ACM. https://doi.org/10.1145/1137856.1137877'
chicago: Cohen Steiner, David, Herbert Edelsbrunner, and Dmitriy Morozov. “Vines
and Vineyards by Updating Persistence in Linear Time,” 119–26. ACM, 2006. https://doi.org/10.1145/1137856.1137877.
ieee: 'D. Cohen Steiner, H. Edelsbrunner, and D. Morozov, “Vines and vineyards by
updating persistence in linear time,” presented at the SCG: Symposium on Computational
Geometry, 2006, pp. 119–126.'
ista: 'Cohen Steiner D, Edelsbrunner H, Morozov D. 2006. Vines and vineyards by
updating persistence in linear time. SCG: Symposium on Computational Geometry,
119–126.'
mla: Cohen Steiner, David, et al. Vines and Vineyards by Updating Persistence
in Linear Time. ACM, 2006, pp. 119–26, doi:10.1145/1137856.1137877.
short: D. Cohen Steiner, H. Edelsbrunner, D. Morozov, in:, ACM, 2006, pp. 119–126.
conference:
name: 'SCG: Symposium on Computational Geometry'
date_created: 2018-12-11T12:03:58Z
date_published: 2006-06-01T00:00:00Z
date_updated: 2021-01-12T07:44:18Z
day: '01'
doi: 10.1145/1137856.1137877
extern: 1
month: '06'
page: 119 - 126
publication_status: published
publisher: ACM
publist_id: '2826'
quality_controlled: 0
status: public
title: Vines and vineyards by updating persistence in linear time
type: conference
year: '2006'
...
---
_id: '3560'
abstract:
- lang: eng
text: We continue the study of topological persistence [5] by investigat- ing the
problem of simplifying a function f in a way that removes topological noise as
determined by its persistence diagram [2]. To state our results, we call a function
g an ε-simplification of another function f if ∥f − g∥∞ ≤ ε, and the persistence
diagrams of g are the same as those of f except all points within L1-distance
at most ε from the diagonal have been removed. We prove that for func- tions f
on a 2-manifold such ε-simplification exists, and we give an algorithm to construct
them in the piecewise linear case.
acknowledgement: Partially supported by NSF under grant CCR-00-86013, by DARPA under
grant HR0011-05-1-0007, and by the Lawrence Livermore National Laboratory under
grant B543154.
author:
- first_name: Herbert
full_name: Herbert Edelsbrunner
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Dmitriy
full_name: Morozov, Dmitriy
last_name: Morozov
- first_name: Valerio
full_name: Pascucci, Valerio
last_name: Pascucci
citation:
ama: 'Edelsbrunner H, Morozov D, Pascucci V. Persistence-sensitive simplification
of functions on 2-manifolds. In: ACM; 2006:127-134. doi:10.1145/1137856.1137878'
apa: 'Edelsbrunner, H., Morozov, D., & Pascucci, V. (2006). Persistence-sensitive
simplification of functions on 2-manifolds (pp. 127–134). Presented at the SCG:
Symposium on Computational Geometry, ACM. https://doi.org/10.1145/1137856.1137878'
chicago: Edelsbrunner, Herbert, Dmitriy Morozov, and Valerio Pascucci. “Persistence-Sensitive
Simplification of Functions on 2-Manifolds,” 127–34. ACM, 2006. https://doi.org/10.1145/1137856.1137878.
ieee: 'H. Edelsbrunner, D. Morozov, and V. Pascucci, “Persistence-sensitive simplification
of functions on 2-manifolds,” presented at the SCG: Symposium on Computational
Geometry, 2006, pp. 127–134.'
ista: 'Edelsbrunner H, Morozov D, Pascucci V. 2006. Persistence-sensitive simplification
of functions on 2-manifolds. SCG: Symposium on Computational Geometry, 127–134.'
mla: Edelsbrunner, Herbert, et al. Persistence-Sensitive Simplification of Functions
on 2-Manifolds. ACM, 2006, pp. 127–34, doi:10.1145/1137856.1137878.
short: H. Edelsbrunner, D. Morozov, V. Pascucci, in:, ACM, 2006, pp. 127–134.
conference:
name: 'SCG: Symposium on Computational Geometry'
date_created: 2018-12-11T12:03:58Z
date_published: 2006-06-01T00:00:00Z
date_updated: 2021-01-12T07:44:19Z
day: '01'
doi: 10.1145/1137856.1137878
extern: 1
main_file_link:
- open_access: '0'
url: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.132.4465
month: '06'
page: 127 - 134
publication_status: published
publisher: ACM
publist_id: '2825'
quality_controlled: 0
status: public
title: Persistence-sensitive simplification of functions on 2-manifolds
type: conference
year: '2006'
...
---
_id: '3594'
author:
- first_name: Josephine
full_name: Pemberton, Josephine M
last_name: Pemberton
- first_name: Graeme
full_name: Swanson, Graeme M
last_name: Swanson
- first_name: Nicholas H
full_name: Nicholas Barton
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Suzanne
full_name: Livingstone, Suzanne R
last_name: Livingstone
- first_name: Helen
full_name: Senn, Helen V
last_name: Senn
citation:
ama: Pemberton J, Swanson G, Barton NH, Livingstone S, Senn H. Hybridisation between
red and sika deer in Scotland. Deer. 2006;13(9):22-26.
apa: Pemberton, J., Swanson, G., Barton, N. H., Livingstone, S., & Senn, H.
(2006). Hybridisation between red and sika deer in Scotland. Deer. BDS
.
chicago: Pemberton, Josephine, Graeme Swanson, Nicholas H Barton, Suzanne Livingstone,
and Helen Senn. “Hybridisation between Red and Sika Deer in Scotland.” Deer.
BDS , 2006.
ieee: J. Pemberton, G. Swanson, N. H. Barton, S. Livingstone, and H. Senn, “Hybridisation
between red and sika deer in Scotland,” Deer, vol. 13, no. 9. BDS , pp.
22–26, 2006.
ista: Pemberton J, Swanson G, Barton NH, Livingstone S, Senn H. 2006. Hybridisation
between red and sika deer in Scotland. Deer. 13(9), 22–26.
mla: Pemberton, Josephine, et al. “Hybridisation between Red and Sika Deer in Scotland.”
Deer, vol. 13, no. 9, BDS , 2006, pp. 22–26.
short: J. Pemberton, G. Swanson, N.H. Barton, S. Livingstone, H. Senn, Deer 13 (2006)
22–26.
date_created: 2018-12-11T12:04:08Z
date_published: 2006-01-01T00:00:00Z
date_updated: 2019-04-26T07:22:31Z
day: '01'
extern: 1
intvolume: ' 13'
issue: '9'
month: '01'
page: 22 - 26
publication: Deer
publication_status: published
publisher: 'BDS '
publist_id: '2789'
quality_controlled: 0
status: public
title: Hybridisation between red and sika deer in Scotland
type: review
volume: 13
year: '2006'
...
---
_id: '3607'
abstract:
- lang: eng
text: We apply new analytical methods to understand the consequences of population
bottlenecks for expected additive genetic variance. We analyze essentially all
models for multilocus epistasis that have been numerically simulated to demonstrate
increased additive variance. We conclude that for biologically plausible models,
large increases in expected additive variance–attributable to epistasis rather
than dominance–are unlikely. Naciri-Graven and Goudet (2003) found that as the
number of epistatically interacting loci increases, additive variance tends to
be inflated more after a bottleneck. We argue that this result reflects biologically
unrealistic aspects of their models. Specifically, as the number of loci increases,
higher-order epistatic interactions become increasingly important in these models,
with an increasing fraction of the genetic variance becoming nonadditive, contrary
to empirical observations. As shown by Barton and Turelli (2004), without dominance,
conversion of nonadditive to additive variance depends only on the variance components
and not on the number of loci per se. Numerical results indicating that more inbreeding
is needed to produce maximal release of additive variance with more loci follow
directly from our analytical results, which show that high levels of inbreeding
(F > 0.5) are needed for significant conversion of higher-order components.
We discuss alternative approaches to modeling multilocus epistasis and understanding
its consequences.
author:
- first_name: Michael
full_name: Turelli, Michael
last_name: Turelli
- first_name: Nicholas H
full_name: Nicholas Barton
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Turelli M, Barton NH. Will population bottlenecks and multilocus epistasis
increase additive genetic variance? Evolution; International Journal of Organic
Evolution. 2006;60(9):1763-1776. doi:10.1111/j.0014-3820.2006.tb00521.x
apa: Turelli, M., & Barton, N. H. (2006). Will population bottlenecks and multilocus
epistasis increase additive genetic variance? Evolution; International Journal
of Organic Evolution. Wiley-Blackwell. https://doi.org/10.1111/j.0014-3820.2006.tb00521.x
chicago: Turelli, Michael, and Nicholas H Barton. “Will Population Bottlenecks and
Multilocus Epistasis Increase Additive Genetic Variance?” Evolution; International
Journal of Organic Evolution. Wiley-Blackwell, 2006. https://doi.org/10.1111/j.0014-3820.2006.tb00521.x.
ieee: M. Turelli and N. H. Barton, “Will population bottlenecks and multilocus epistasis
increase additive genetic variance?,” Evolution; International Journal of Organic
Evolution, vol. 60, no. 9. Wiley-Blackwell, pp. 1763–1776, 2006.
ista: Turelli M, Barton NH. 2006. Will population bottlenecks and multilocus epistasis
increase additive genetic variance? Evolution; International Journal of Organic
Evolution. 60(9), 1763–1776.
mla: Turelli, Michael, and Nicholas H. Barton. “Will Population Bottlenecks and
Multilocus Epistasis Increase Additive Genetic Variance?” Evolution; International
Journal of Organic Evolution, vol. 60, no. 9, Wiley-Blackwell, 2006, pp. 1763–76,
doi:10.1111/j.0014-3820.2006.tb00521.x.
short: M. Turelli, N.H. Barton, Evolution; International Journal of Organic Evolution
60 (2006) 1763–1776.
date_created: 2018-12-11T12:04:13Z
date_published: 2006-09-01T00:00:00Z
date_updated: 2021-01-12T07:44:37Z
day: '01'
doi: 10.1111/j.0014-3820.2006.tb00521.x
extern: 1
intvolume: ' 60'
issue: '9'
month: '09'
page: 1763 - 1776
publication: Evolution; International Journal of Organic Evolution
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2776'
quality_controlled: 0
status: public
title: Will population bottlenecks and multilocus epistasis increase additive genetic
variance?
type: journal_article
volume: 60
year: '2006'
...
---
_id: '3608'
abstract:
- lang: eng
text: 'We study the evolution of inversions that capture locally adapted alleles
when two populations are exchanging migrants or hybridizing. By suppressing recombination
between the loci, a new inversion can spread. Neither drift nor coadaptation between
the alleles (epistasis) is needed, so this local adaptation mechanism may apply
to a broader range of genetic and demographic situations than alternative hypotheses
that have been widely discussed. The mechanism can explain many features observed
in inversion systems. It will drive an inversion to high frequency if there is
no countervailing force, which could explain fixed differences observed between
populations and species. An inversion can be stabilized at an intermediate frequency
if it also happens to capture one or more deleterious recessive mutations, which
could explain polymorphisms that are common in some species. This polymorphism
can cycle in frequency with the changing selective advantage of the locally favored
alleles. The mechanism can establish underdominant inversions that decrease heterokaryotype
fitness by several percent if the cause of fitness loss is structural, while if
the cause is genic there is no limit to the strength of underdominance that can
result. The mechanism is expected to cause loci responsible for adaptive species-specific
differences to map to inversions, as seen in recent QTL studies. We discuss data
that support the hypothesis, review other mechanisms for inversion evolution,
and suggest possible tests. '
author:
- first_name: Mark
full_name: Kirkpatrick, Mark
last_name: Kirkpatrick
- first_name: Nicholas H
full_name: Nicholas Barton
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Kirkpatrick M, Barton NH. Chromosome inversions, local adaptation, and speciation.
Genetics. 2006;173(1):419-434. doi:10.1534/genetics.105.047985
apa: Kirkpatrick, M., & Barton, N. H. (2006). Chromosome inversions, local adaptation,
and speciation. Genetics. Genetics Society of America. https://doi.org/10.1534/genetics.105.047985
chicago: Kirkpatrick, Mark, and Nicholas H Barton. “Chromosome Inversions, Local
Adaptation, and Speciation.” Genetics. Genetics Society of America, 2006.
https://doi.org/10.1534/genetics.105.047985.
ieee: M. Kirkpatrick and N. H. Barton, “Chromosome inversions, local adaptation,
and speciation,” Genetics, vol. 173, no. 1. Genetics Society of America,
pp. 419–434, 2006.
ista: Kirkpatrick M, Barton NH. 2006. Chromosome inversions, local adaptation, and
speciation. Genetics. 173(1), 419–434.
mla: Kirkpatrick, Mark, and Nicholas H. Barton. “Chromosome Inversions, Local Adaptation,
and Speciation.” Genetics, vol. 173, no. 1, Genetics Society of America,
2006, pp. 419–34, doi:10.1534/genetics.105.047985.
short: M. Kirkpatrick, N.H. Barton, Genetics 173 (2006) 419–434.
date_created: 2018-12-11T12:04:13Z
date_published: 2006-05-01T00:00:00Z
date_updated: 2021-01-12T07:44:37Z
day: '01'
doi: 10.1534/genetics.105.047985
extern: 1
intvolume: ' 173'
issue: '1'
month: '05'
page: 419 - 434
publication: Genetics
publication_status: published
publisher: Genetics Society of America
publist_id: '2775'
quality_controlled: 0
status: public
title: Chromosome inversions, local adaptation, and speciation
type: journal_article
volume: 173
year: '2006'
...
---
_id: '3609'
abstract:
- lang: eng
text: Bombina bombina and B. variegata are two anciently diverged toad taxa that
have adapted to different breeding habitats yet hybridize freely in zones of overlap
where their parapatric distributions meet. Here, we report on a joint genetic
and ecological analysis of a hybrid zone in the vicinity of Stryi in western Ukraine.
We used five unlinked allozyme loci, two nuclear single nucleotide polymorphisms
and a mitochondrial DNA haplotype as genetic markers. Parallel allele frequency
clines with a sharp central step occur across a sharp ecotone, where transitions
in aquatic habitat, elevation, and terrestrial vegetation coincide. The width
of the hybrid zone, estimated as the inverse of the maximum gradient in allele
frequency, is 2.3 km. This is the smallest of four estimates derived from different
clinal transects across Europe. We argue that the narrow cline near Stryi is mainly
due to a combination of habitat distribution and habitat preference. Adult toads
show a preference for either ponds (B. bombina) or puddles (B. variegata), which
is known to affect the distribution of genotypes within the hybrid zones. At Stryi,
it should cause a reduction of the dispersal rate across the ecotone and thus
narrow the cline. A detailed comparison of all five intensively studied Bombina
transects lends support to the hypothesis that habitat distribution plus habitat
preference can jointly affect the structure of hybrid zones and, ultimately, the
resulting barriers to gene flow between differentiated gene pools. This study
also represents a resampling of an area that was last studied more than 70 years
ago. Our allele-frequency clines largely coincide with those that were described
then on the basis of morphological variation. However, we found asymmetrical introgression
of B. variegata genes into B. bombina territory along the bank of a river.
author:
- first_name: Alexey
full_name: Yanchukov, Alexey
last_name: Yanchukov
- first_name: Sebastian
full_name: Hofman, Sebastian
last_name: Hofman
- first_name: Jacek
full_name: Szymura, Jacek M
last_name: Szymura
- first_name: Sergey
full_name: Mezhzherin, Sergey V
last_name: Mezhzherin
- first_name: Sviatoslav
full_name: Morozov-Leonov, Sviatoslav
last_name: Morozov Leonov
- first_name: Nicholas H
full_name: Nicholas Barton
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Beate
full_name: Nürnberger, Beate
last_name: Nürnberger
citation:
ama: 'Yanchukov A, Hofman S, Szymura J, et al. Hybridization of Bombina bombina
and B. variegata (Anura, Discoglossidae) at a sharp ecotone in western Ukraine:
comparisons across transects and over time. Evolution; International Journal
of Organic Evolution. 2006;60(3):583-600. doi:10.1111/j.0014-3820.2006.tb01139.x'
apa: 'Yanchukov, A., Hofman, S., Szymura, J., Mezhzherin, S., Morozov Leonov, S.,
Barton, N. H., & Nürnberger, B. (2006). Hybridization of Bombina bombina and
B. variegata (Anura, Discoglossidae) at a sharp ecotone in western Ukraine: comparisons
across transects and over time. Evolution; International Journal of Organic
Evolution. Wiley-Blackwell. https://doi.org/10.1111/j.0014-3820.2006.tb01139.x'
chicago: 'Yanchukov, Alexey, Sebastian Hofman, Jacek Szymura, Sergey Mezhzherin,
Sviatoslav Morozov Leonov, Nicholas H Barton, and Beate Nürnberger. “Hybridization
of Bombina Bombina and B. Variegata (Anura, Discoglossidae) at a Sharp Ecotone
in Western Ukraine: Comparisons across Transects and over Time.” Evolution;
International Journal of Organic Evolution. Wiley-Blackwell, 2006. https://doi.org/10.1111/j.0014-3820.2006.tb01139.x.'
ieee: 'A. Yanchukov et al., “Hybridization of Bombina bombina and B. variegata
(Anura, Discoglossidae) at a sharp ecotone in western Ukraine: comparisons across
transects and over time,” Evolution; International Journal of Organic Evolution,
vol. 60, no. 3. Wiley-Blackwell, pp. 583–600, 2006.'
ista: 'Yanchukov A, Hofman S, Szymura J, Mezhzherin S, Morozov Leonov S, Barton
NH, Nürnberger B. 2006. Hybridization of Bombina bombina and B. variegata (Anura,
Discoglossidae) at a sharp ecotone in western Ukraine: comparisons across transects
and over time. Evolution; International Journal of Organic Evolution. 60(3), 583–600.'
mla: 'Yanchukov, Alexey, et al. “Hybridization of Bombina Bombina and B. Variegata
(Anura, Discoglossidae) at a Sharp Ecotone in Western Ukraine: Comparisons across
Transects and over Time.” Evolution; International Journal of Organic Evolution,
vol. 60, no. 3, Wiley-Blackwell, 2006, pp. 583–600, doi:10.1111/j.0014-3820.2006.tb01139.x.'
short: A. Yanchukov, S. Hofman, J. Szymura, S. Mezhzherin, S. Morozov Leonov, N.H.
Barton, B. Nürnberger, Evolution; International Journal of Organic Evolution 60
(2006) 583–600.
date_created: 2018-12-11T12:04:13Z
date_published: 2006-03-01T00:00:00Z
date_updated: 2021-01-12T07:44:38Z
day: '01'
doi: 10.1111/j.0014-3820.2006.tb01139.x
extern: 1
intvolume: ' 60'
issue: '3'
month: '03'
page: 583 - 600
publication: Evolution; International Journal of Organic Evolution
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2774'
quality_controlled: 0
status: public
title: 'Hybridization of Bombina bombina and B. variegata (Anura, Discoglossidae)
at a sharp ecotone in western Ukraine: comparisons across transects and over time'
type: journal_article
volume: 60
year: '2006'
...
---
_id: '3610'
abstract:
- lang: eng
text: For a model of diallelic loci with arbitrary epistasis, Barton and Turelli
[2004. Effects of genetic drift on variance components under a general model of
epistasis. Evolution 58, 2111–2132] gave results for variances among and within
replicate lines obtained by inbreeding without selection. Here, we discuss the
relation between their population genetic methods and classical quantitative genetic
arguments. In particular, we consider the case of no dominance using classical
identity by descent arguments, which generalizes their results from two alleles
to multiple alleles. To clarify the connections between the alternative methods,
we obtain the same results using an intermediate method, which explicitly identifies
the statistical effects of sets of loci. We also discuss the effects of population
bottlenecks on covariances among relatives.
author:
- first_name: William
full_name: Hill, William G
last_name: Hill
- first_name: Nicholas H
full_name: Nicholas Barton
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Michael
full_name: Turelli, Michael
last_name: Turelli
citation:
ama: Hill W, Barton NH, Turelli M. Prediction of effects of genetic drift on variance
components under a general model of epistasis. Theoretical Population Biology.
2006;70(1):56-62. doi:10.1016/j.tpb.2005.10.001
apa: Hill, W., Barton, N. H., & Turelli, M. (2006). Prediction of effects of
genetic drift on variance components under a general model of epistasis. Theoretical
Population Biology. Academic Press. https://doi.org/10.1016/j.tpb.2005.10.001
chicago: Hill, William, Nicholas H Barton, and Michael Turelli. “Prediction of Effects
of Genetic Drift on Variance Components under a General Model of Epistasis.” Theoretical
Population Biology. Academic Press, 2006. https://doi.org/10.1016/j.tpb.2005.10.001.
ieee: W. Hill, N. H. Barton, and M. Turelli, “Prediction of effects of genetic drift
on variance components under a general model of epistasis,” Theoretical Population
Biology, vol. 70, no. 1. Academic Press, pp. 56–62, 2006.
ista: Hill W, Barton NH, Turelli M. 2006. Prediction of effects of genetic drift
on variance components under a general model of epistasis. Theoretical Population
Biology. 70(1), 56–62.
mla: Hill, William, et al. “Prediction of Effects of Genetic Drift on Variance Components
under a General Model of Epistasis.” Theoretical Population Biology, vol.
70, no. 1, Academic Press, 2006, pp. 56–62, doi:10.1016/j.tpb.2005.10.001.
short: W. Hill, N.H. Barton, M. Turelli, Theoretical Population Biology 70 (2006)
56–62.
date_created: 2018-12-11T12:04:14Z
date_published: 2006-08-01T00:00:00Z
date_updated: 2021-01-12T07:44:39Z
day: '01'
doi: 10.1016/j.tpb.2005.10.001
extern: 1
intvolume: ' 70'
issue: '1'
month: '08'
page: 56 - 62
publication: Theoretical Population Biology
publication_status: published
publisher: Academic Press
publist_id: '2773'
quality_controlled: 0
status: public
title: Prediction of effects of genetic drift on variance components under a general
model of epistasis
type: journal_article
volume: 70
year: '2006'
...
---
_id: '3677'
abstract:
- lang: eng
text: We propose a video retrieval framework based on a novel combination of spatiograms
and the Jensen-Shannon divergence, and validate its performance in two quantitative
experiments on TRECVID BBC Rushes data. In the first experiment, color-based methods
are tested by grouping redundant shots in an unsupervised clustering. Results
of the second experiment show that motion-based spatiograms make a promising fast,
compressed-domain descriptor for the detection of interview scenes.
alternative_title:
- TRECVID Notebook Papers and Slides
author:
- first_name: Adrian
full_name: Ulges, Adrian
last_name: Ulges
- first_name: Christoph
full_name: Christoph Lampert
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
- first_name: Daniel
full_name: Keysers,Daniel
last_name: Keysers
citation:
ama: 'Ulges A, Lampert C, Keysers D. Spatiogram-based shot distances for video retrieval.
In: NIST (National Institute of Standards and Technology, US Department of Commerce);
2006:1-10.'
apa: Ulges, A., Lampert, C., & Keysers, D. (2006). Spatiogram-based shot distances
for video retrieval (pp. 1–10). Presented at the TRECVID Workshop, NIST (National
Institute of Standards and Technology, US Department of Commerce).
chicago: Ulges, Adrian, Christoph Lampert, and Daniel Keysers. “Spatiogram-Based
Shot Distances for Video Retrieval,” 1–10. NIST (National Institute of Standards
and Technology, US Department of Commerce), 2006.
ieee: A. Ulges, C. Lampert, and D. Keysers, “Spatiogram-based shot distances for
video retrieval,” presented at the TRECVID Workshop, 2006, pp. 1–10.
ista: Ulges A, Lampert C, Keysers D. 2006. Spatiogram-based shot distances for video
retrieval. TRECVID Workshop, TRECVID Notebook Papers and Slides, , 1–10.
mla: Ulges, Adrian, et al. Spatiogram-Based Shot Distances for Video Retrieval.
NIST (National Institute of Standards and Technology, US Department of Commerce),
2006, pp. 1–10.
short: A. Ulges, C. Lampert, D. Keysers, in:, NIST (National Institute of Standards
and Technology, US Department of Commerce), 2006, pp. 1–10.
conference:
name: TRECVID Workshop
date_created: 2018-12-11T12:04:34Z
date_published: 2006-11-14T00:00:00Z
date_updated: 2021-01-12T07:45:04Z
day: '14'
extern: 1
main_file_link:
- open_access: '0'
url: http://www-nlpir.nist.gov/projects/tvpubs/tv6.papers/dfki.pdf
month: '11'
page: 1 - 10
publication_status: published
publisher: NIST (National Institute of Standards and Technology, US Department of
Commerce)
publist_id: '2702'
quality_controlled: 0
status: public
title: Spatiogram-based shot distances for video retrieval
type: conference
year: '2006'
...
---
_id: '3679'
abstract:
- lang: eng
text: This paper describes a new system for "Finding Satellite Tracks” in astronomical
images based on the modern geometric approach. There is an increasing need of
using methods with solid mathematical and statistical foundation in astronomical
image processing. Where the computational methods are serving in all disciplines
of science, they are becoming popular in the field of astronomy as well. Currently
different computational systems are required to be numerically optimized before
to get applied on astronomical images. So at present there is no single system
which solves the problems of astronomers using computational methods based on
modern approaches. The system "Finding Satellite Tracks” is based on geometric
matching method "Recognition by Adaptive Subdivision of Transformation Space
(RAST)".
alternative_title:
- LNCS
author:
- first_name: Haider
full_name: Ali,Haider
last_name: Ali
- first_name: Christoph
full_name: Christoph Lampert
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
- first_name: Thomas
full_name: Breuel,Thomas M
last_name: Breuel
citation:
ama: 'Ali H, Lampert C, Breuel T. Satellite tracks removal in astronomical images.
In: Vol 4225. Springer; 2006:892-901. doi:10.1007/11892755_92'
apa: 'Ali, H., Lampert, C., & Breuel, T. (2006). Satellite tracks removal in
astronomical images (Vol. 4225, pp. 892–901). Presented at the CIARP: Iberoamerican
Congress in Pattern Recognition, Springer. https://doi.org/10.1007/11892755_92'
chicago: Ali, Haider, Christoph Lampert, and Thomas Breuel. “Satellite Tracks Removal
in Astronomical Images,” 4225:892–901. Springer, 2006. https://doi.org/10.1007/11892755_92.
ieee: 'H. Ali, C. Lampert, and T. Breuel, “Satellite tracks removal in astronomical
images,” presented at the CIARP: Iberoamerican Congress in Pattern Recognition,
2006, vol. 4225, pp. 892–901.'
ista: 'Ali H, Lampert C, Breuel T. 2006. Satellite tracks removal in astronomical
images. CIARP: Iberoamerican Congress in Pattern Recognition, LNCS, vol. 4225,
892–901.'
mla: Ali, Haider, et al. Satellite Tracks Removal in Astronomical Images.
Vol. 4225, Springer, 2006, pp. 892–901, doi:10.1007/11892755_92.
short: H. Ali, C. Lampert, T. Breuel, in:, Springer, 2006, pp. 892–901.
conference:
name: 'CIARP: Iberoamerican Congress in Pattern Recognition'
date_created: 2018-12-11T12:04:35Z
date_published: 2006-10-31T00:00:00Z
date_updated: 2021-01-12T07:45:05Z
day: '31'
doi: 10.1007/11892755_92
extern: 1
intvolume: ' 4225'
main_file_link:
- open_access: '0'
url: http://pub.ist.ac.at/~chl/papers/ali-ciarp2006.pdf
month: '10'
page: 892 - 901
publication_status: published
publisher: Springer
publist_id: '2700'
quality_controlled: 0
status: public
title: Satellite tracks removal in astronomical images
type: conference
volume: 4225
year: '2006'
...
---
_id: '3680'
abstract:
- lang: eng
text: The detection of counterfeit in printed documents is currently based mainly
on built-in security features or on human expertise. We propose a classification
system that supports non-expert users to distinguish original documents from PC-made
forgeries by analyzing the printing technique used. Each letter in a document
is classified using a support vector machine that has been trained to distinguish
laser from inkjet printouts. A color-coded visualization helps the user to interpret
the per-letter classification results
author:
- first_name: Christoph
full_name: Christoph Lampert
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
- first_name: Lin
full_name: Mei,Lin
last_name: Mei
- first_name: Thomas
full_name: Breuel,Thomas M
last_name: Breuel
citation:
ama: 'Lampert C, Mei L, Breuel T. Printing technique classification for document
counterfeit detection. In: Vol 1. IEEE; 2006:639-634. doi:10.1109/ICCIAS.2006.294214'
apa: 'Lampert, C., Mei, L., & Breuel, T. (2006). Printing technique classification
for document counterfeit detection (Vol. 1, pp. 639–634). Presented at the CIS:
Computational Intelligence and Security, IEEE. https://doi.org/10.1109/ICCIAS.2006.294214'
chicago: Lampert, Christoph, Lin Mei, and Thomas Breuel. “Printing Technique Classification
for Document Counterfeit Detection,” 1:639–634. IEEE, 2006. https://doi.org/10.1109/ICCIAS.2006.294214.
ieee: 'C. Lampert, L. Mei, and T. Breuel, “Printing technique classification for
document counterfeit detection,” presented at the CIS: Computational Intelligence
and Security, 2006, vol. 1, pp. 639–634.'
ista: 'Lampert C, Mei L, Breuel T. 2006. Printing technique classification for document
counterfeit detection. CIS: Computational Intelligence and Security vol. 1, 639–634.'
mla: Lampert, Christoph, et al. Printing Technique Classification for Document
Counterfeit Detection. Vol. 1, IEEE, 2006, pp. 639–634, doi:10.1109/ICCIAS.2006.294214.
short: C. Lampert, L. Mei, T. Breuel, in:, IEEE, 2006, pp. 639–634.
conference:
name: 'CIS: Computational Intelligence and Security'
date_created: 2018-12-11T12:04:35Z
date_published: 2006-11-03T00:00:00Z
date_updated: 2021-01-12T07:45:06Z
day: '03'
doi: 10.1109/ICCIAS.2006.294214
extern: 1
intvolume: ' 1'
main_file_link:
- open_access: '0'
url: http://pub.ist.ac.at/~chl/papers/lampert-cis2006.pdf
month: '11'
page: 639 - 634
publication_status: published
publisher: IEEE
publist_id: '2698'
quality_controlled: 0
status: public
title: Printing technique classification for document counterfeit detection
type: conference
volume: 1
year: '2006'
...
---
_id: '3683'
abstract:
- lang: eng
text: Many algorithms to remove distortion from document images have be proposed
in recent years, but so far there is no reliable method for comparing their performance.
In this paper we propose a collection of methods to measure the quality of such
restoration algorithms for document image which show a non-linear distortion due
to perspective or page curl. For the result from these measurement to be meaningful,
a common data set of ground truth is required. We therefore started with the buildup
of a document image database that is meant to serve as a common data basis for
all kinds of restoration from images of 3D-shaped document. The long term goal
would be to establish this database and following extensions in the area of document
image dewarping as an as fruitful and indispensable tool as e.g. the NIST database
is for OCR, or the Caltech database is for object and face recognition.
author:
- first_name: Christoph
full_name: Christoph Lampert
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
- first_name: Thomas
full_name: Breuel,Thomas M
last_name: Breuel
citation:
ama: 'Lampert C, Breuel T. Objective quality measurement for geometric document
image restoration. In: Springer; 2006.'
apa: 'Lampert, C., & Breuel, T. (2006). Objective quality measurement for geometric
document image restoration. Presented at the DAS: Document Analysis Systems, Springer.'
chicago: Lampert, Christoph, and Thomas Breuel. “Objective Quality Measurement for
Geometric Document Image Restoration.” Springer, 2006.
ieee: 'C. Lampert and T. Breuel, “Objective quality measurement for geometric document
image restoration,” presented at the DAS: Document Analysis Systems, 2006.'
ista: 'Lampert C, Breuel T. 2006. Objective quality measurement for geometric document
image restoration. DAS: Document Analysis Systems.'
mla: Lampert, Christoph, and Thomas Breuel. Objective Quality Measurement for
Geometric Document Image Restoration. Springer, 2006.
short: C. Lampert, T. Breuel, in:, Springer, 2006.
conference:
name: 'DAS: Document Analysis Systems'
date_created: 2018-12-11T12:04:36Z
date_published: 2006-03-16T00:00:00Z
date_updated: 2021-01-12T07:45:07Z
day: '16'
extern: 1
main_file_link:
- open_access: '0'
url: http://pub.ist.ac.at/~chl/papers/lampert-das2006.pdf
month: '03'
publication_status: published
publisher: Springer
publist_id: '2692'
quality_controlled: 0
status: public
title: Objective quality measurement for geometric document image restoration
type: conference
year: '2006'
...
---
_id: '3685'
abstract:
- lang: eng
text: 'Video compression currently is dominated by engineering and fine-tuned heuristic
methods. In this paper, we propose to instead apply the well-developed machinery
of machine learning in order to support the optimization of existing video encoders
and the creation of new ones. Exemplarily, we show how by machine learning we
can improve one encoding step that is crucial for the performance of all current
video standards: macroblock mode decision. By formulating the problem in a Bayesian
setup, we show that macroblock mode decision can be reduced to a classification
problem with a cost function for misclassification that is sample dependent. We
demonstrate how to apply different machine learning techniques to obtain suitable
classifiers and we show in detailed experiments that all of these perform better
than the state-of-the-art heuristic method'
author:
- first_name: Christoph
full_name: Christoph Lampert
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
citation:
ama: 'Lampert C. Machine learning for video compression: Macroblock mode decision.
In: IEEE; 2006:936-940. doi:10.1109/ICPR.2006.778'
apa: 'Lampert, C. (2006). Machine learning for video compression: Macroblock mode
decision (pp. 936–940). Presented at the ICPR: International Conference on Pattern
Recognition, IEEE. https://doi.org/10.1109/ICPR.2006.778'
chicago: 'Lampert, Christoph. “Machine Learning for Video Compression: Macroblock
Mode Decision,” 936–40. IEEE, 2006. https://doi.org/10.1109/ICPR.2006.778.'
ieee: 'C. Lampert, “Machine learning for video compression: Macroblock mode decision,”
presented at the ICPR: International Conference on Pattern Recognition, 2006,
pp. 936–940.'
ista: 'Lampert C. 2006. Machine learning for video compression: Macroblock mode
decision. ICPR: International Conference on Pattern Recognition, 936–940.'
mla: 'Lampert, Christoph. Machine Learning for Video Compression: Macroblock
Mode Decision. IEEE, 2006, pp. 936–40, doi:10.1109/ICPR.2006.778.'
short: C. Lampert, in:, IEEE, 2006, pp. 936–940.
conference:
name: 'ICPR: International Conference on Pattern Recognition'
date_created: 2018-12-11T12:04:37Z
date_published: 2006-09-18T00:00:00Z
date_updated: 2021-01-12T07:45:08Z
day: '18'
doi: 10.1109/ICPR.2006.778
extern: 1
month: '09'
page: 936 - 940
publication_status: published
publisher: IEEE
publist_id: '2689'
quality_controlled: 0
status: public
title: 'Machine learning for video compression: Macroblock mode decision'
type: conference
year: '2006'
...
---
_id: '3692'
author:
- first_name: Daniel
full_name: Keysers,Daniel
last_name: Keysers
- first_name: Christoph
full_name: Christoph Lampert
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
- first_name: Thomas
full_name: Breuel,Thomas M
last_name: Breuel
citation:
ama: 'Keysers D, Lampert C, Breuel T. Color image dequantization by constrained
diffusion. In: Vol 6058. SPIE; 2006. doi:10.1117/12.648713'
apa: Keysers, D., Lampert, C., & Breuel, T. (2006). Color image dequantization
by constrained diffusion (Vol. 6058). Presented at the SPIE Electronic Imaging,
SPIE. https://doi.org/10.1117/12.648713
chicago: Keysers, Daniel, Christoph Lampert, and Thomas Breuel. “Color Image Dequantization
by Constrained Diffusion,” Vol. 6058. SPIE, 2006. https://doi.org/10.1117/12.648713.
ieee: D. Keysers, C. Lampert, and T. Breuel, “Color image dequantization by constrained
diffusion,” presented at the SPIE Electronic Imaging, 2006, vol. 6058.
ista: Keysers D, Lampert C, Breuel T. 2006. Color image dequantization by constrained
diffusion. SPIE Electronic Imaging vol. 6058.
mla: Keysers, Daniel, et al. Color Image Dequantization by Constrained Diffusion.
Vol. 6058, SPIE, 2006, doi:10.1117/12.648713.
short: D. Keysers, C. Lampert, T. Breuel, in:, SPIE, 2006.
conference:
name: SPIE Electronic Imaging
date_created: 2018-12-11T12:04:39Z
date_published: 2006-01-15T00:00:00Z
date_updated: 2019-05-10T12:19:52Z
day: '15'
doi: 10.1117/12.648713
extern: 1
intvolume: ' 6058'
month: '01'
publication_status: published
publisher: SPIE
publist_id: '2674'
quality_controlled: 0
status: public
title: Color image dequantization by constrained diffusion
type: conference
volume: 6058
year: '2006'
...
---
_id: '3693'
abstract:
- lang: eng
text: Gaussian filtering in one, two or three dimensions is among the most commonly
needed tasks in signal and image processing. Finite impulse response filters in
the time domain with Gaussian masks are easy to implement in either floating or
fixed point arithmetic, because Gaussian kernels are strictly positive and bounded.
But these implementations are slow for large images or kernels. With the recursive
IIR-filters and FFT-based methods, there are at least two alternative methods
to perform Gaussian filtering in a faster way, but so far they are only applicable
when floating-point hardware is available. In this paper, a fixed-point implementation
of recursive Gaussian filtering is discussed and applied to isotropic and anisotropic
image filtering by making use of a non-orthogonal separation scheme of the Gaussian
filter.
author:
- first_name: Christoph
full_name: Christoph Lampert
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
- first_name: Oliver
full_name: Wirjadi,Oliver
last_name: Wirjadi
citation:
ama: 'Lampert C, Wirjadi O. Anisotropic Gaussian filtering using fixed point arithmetic.
In: IEEE; 2006:1565-1568. doi:10.1109/ICIP.2006.312606'
apa: 'Lampert, C., & Wirjadi, O. (2006). Anisotropic Gaussian filtering using
fixed point arithmetic (pp. 1565–1568). Presented at the ICIP: IEEE International
Conference on Image Processing, IEEE. https://doi.org/10.1109/ICIP.2006.312606'
chicago: Lampert, Christoph, and Oliver Wirjadi. “Anisotropic Gaussian Filtering
Using Fixed Point Arithmetic,” 1565–68. IEEE, 2006. https://doi.org/10.1109/ICIP.2006.312606.
ieee: 'C. Lampert and O. Wirjadi, “Anisotropic Gaussian filtering using fixed point
arithmetic,” presented at the ICIP: IEEE International Conference on Image Processing,
2006, pp. 1565–1568.'
ista: 'Lampert C, Wirjadi O. 2006. Anisotropic Gaussian filtering using fixed point
arithmetic. ICIP: IEEE International Conference on Image Processing, 1565–1568.'
mla: Lampert, Christoph, and Oliver Wirjadi. Anisotropic Gaussian Filtering Using
Fixed Point Arithmetic. IEEE, 2006, pp. 1565–68, doi:10.1109/ICIP.2006.312606.
short: C. Lampert, O. Wirjadi, in:, IEEE, 2006, pp. 1565–1568.
conference:
name: 'ICIP: IEEE International Conference on Image Processing'
date_created: 2018-12-11T12:04:39Z
date_published: 2006-10-08T00:00:00Z
date_updated: 2021-01-12T07:49:00Z
day: '08'
doi: 10.1109/ICIP.2006.312606
extern: 1
month: '10'
page: 1565 - 1568
publication_status: published
publisher: IEEE
publist_id: '2670'
quality_controlled: 0
status: public
title: Anisotropic Gaussian filtering using fixed point arithmetic
type: conference
year: '2006'
...
---
_id: '3695'
abstract:
- lang: eng
text: We give an analytical and geometrical treatment of what it means to separate
a Gaussian kernel along arbitrary axes in Ropfn, and we present a separation scheme
that allows us to efficiently implement anisotropic Gaussian convolution filters
for data of arbitrary dimensionality. Based on our previous analysis we show that
this scheme is optimal with regard to the number of memory accesses and interpolation
operations needed. The proposed method relies on nonorthogonal convolution axes
and works completely in image space. Thus, it avoids the need for a fast Fourier
transform (FFT)-subroutine. Depending on the accuracy and speed requirements,
different interpolation schemes and methods to implement the one-dimensional Gaussian
(finite impulse response and infinite impulse response) can be integrated. Special
emphasis is put on analyzing the performance and accuracy of the new method. In
particular, we show that without any special optimization of the source code,
it can perform anisotropic Gaussian filtering faster than methods relying on the
FFT.
author:
- first_name: Christoph
full_name: Christoph Lampert
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
- first_name: Oliver
full_name: Wirjadi,Oliver
last_name: Wirjadi
citation:
ama: Lampert C, Wirjadi O. An optimal non-orthogonal separation of the anisotropic
Gaussian convolution filter. IEEE Transactions on Image Processing (TIP).
2006;15(11):3501-3513. doi:
10.1109/TIP.2006.877501
apa: Lampert, C., & Wirjadi, O. (2006). An optimal non-orthogonal separation
of the anisotropic Gaussian convolution filter. IEEE Transactions on Image
Processing (TIP). IEEE. https://doi.org/ 10.1109/TIP.2006.877501
chicago: Lampert, Christoph, and Oliver Wirjadi. “An Optimal Non-Orthogonal Separation
of the Anisotropic Gaussian Convolution Filter.” IEEE Transactions on Image
Processing (TIP). IEEE, 2006. https://doi.org/ 10.1109/TIP.2006.877501 .
ieee: C. Lampert and O. Wirjadi, “An optimal non-orthogonal separation of the anisotropic
Gaussian convolution filter,” IEEE Transactions on Image Processing (TIP),
vol. 15, no. 11. IEEE, pp. 3501–3513, 2006.
ista: Lampert C, Wirjadi O. 2006. An optimal non-orthogonal separation of the anisotropic
Gaussian convolution filter. IEEE Transactions on Image Processing (TIP). 15(11),
3501–3513.
mla: Lampert, Christoph, and Oliver Wirjadi. “An Optimal Non-Orthogonal Separation
of the Anisotropic Gaussian Convolution Filter.” IEEE Transactions on Image
Processing (TIP), vol. 15, no. 11, IEEE, 2006, pp. 3501–13, doi: 10.1109/TIP.2006.877501 .
short: C. Lampert, O. Wirjadi, IEEE Transactions on Image Processing (TIP) 15 (2006)
3501–3513.
date_created: 2018-12-11T12:04:40Z
date_published: 2006-11-01T00:00:00Z
date_updated: 2021-01-12T07:49:01Z
day: '01'
doi: ' 10.1109/TIP.2006.877501 '
extern: 1
intvolume: ' 15'
issue: '11'
main_file_link:
- open_access: '1'
url: http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:386-kluedo-14003
month: '11'
oa: 1
page: 3501 - 3513
publication: IEEE Transactions on Image Processing (TIP)
publication_status: published
publisher: IEEE
publist_id: '2669'
quality_controlled: 0
status: public
title: An optimal non-orthogonal separation of the anisotropic Gaussian convolution
filter
type: journal_article
volume: 15
year: '2006'
...
---
_id: '3722'
author:
- first_name: Harald L
full_name: Harald Janovjak
id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
last_name: Janovjak
orcid: 0000-0002-8023-9315
- first_name: Daniel
full_name: Mueller, Daniel J
last_name: Mueller
citation:
ama: 'Janovjak HL, Mueller D. Rastersondenmikroskopie. In: Bioanalytik. Spektrum
Akademischer Verlag; 2006.'
apa: Janovjak, H. L., & Mueller, D. (2006). Rastersondenmikroskopie. In Bioanalytik.
Spektrum Akademischer Verlag.
chicago: Janovjak, Harald L, and Daniel Mueller. “Rastersondenmikroskopie.” In Bioanalytik.
Spektrum Akademischer Verlag, 2006.
ieee: H. L. Janovjak and D. Mueller, “Rastersondenmikroskopie,” in Bioanalytik,
Spektrum Akademischer Verlag, 2006.
ista: 'Janovjak HL, Mueller D. 2006.Rastersondenmikroskopie. In: Bioanalytik. .'
mla: Janovjak, Harald L., and Daniel Mueller. “Rastersondenmikroskopie.” Bioanalytik,
Spektrum Akademischer Verlag, 2006.
short: H.L. Janovjak, D. Mueller, in:, Bioanalytik, Spektrum Akademischer Verlag,
2006.
date_created: 2018-12-11T12:04:48Z
date_published: 2006-06-16T00:00:00Z
date_updated: 2021-01-12T07:51:44Z
day: '16'
extern: 1
month: '06'
publication: Bioanalytik
publication_status: published
publisher: Spektrum Akademischer Verlag
publist_id: '2508'
quality_controlled: 0
status: public
title: Rastersondenmikroskopie
type: book_chapter
year: '2006'
...
---
_id: '3728'
abstract:
- lang: eng
text: Mechanical unfolding of single bacteriorhodopsins from a membrane bilayer
is studied using molecular dynamics simulations. The initial conformation of the
lipid membrane is determined through all-atom simulations and then its coarse-grained
representation is used in the studies of stretching. A Go-like model with a realistic
contact map and with Lennard–Jones contact interactions is applied to model the
protein–membrane system. The model qualitatively reproduces the experimentally
observed differences between force-extension patterns obtained on bacteriorhodopsin
at different temperatures and predicts a lack of symmetry in the choice of the
terminus to pull by. It also illustrates the decisive role of the interactions
of the protein with the membrane in determining the force pattern and thus the
stability of transmembrane proteins.
author:
- first_name: Marek
full_name: Cieplak, Marek
last_name: Cieplak
- first_name: Sławomir
full_name: Filipek, Sławomir
last_name: Filipek
- first_name: Harald L
full_name: Harald Janovjak
id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
last_name: Janovjak
orcid: 0000-0002-8023-9315
- first_name: Krystiana
full_name: Krzysko, Krystiana A
last_name: Krzysko
citation:
ama: 'Cieplak M, Filipek S, Janovjak HL, Krzysko K. Pulling single bacteriorhodopsin
out of a membrane: Comparison of simulation and experiment. Biochimica et Biophysica
Acta (BBA) - Biomembranes. 2006;1758(4):537-544. doi:10.1016/j.bbamem.2006.03.028'
apa: 'Cieplak, M., Filipek, S., Janovjak, H. L., & Krzysko, K. (2006). Pulling
single bacteriorhodopsin out of a membrane: Comparison of simulation and experiment.
Biochimica et Biophysica Acta (BBA) - Biomembranes. Elsevier. https://doi.org/10.1016/j.bbamem.2006.03.028'
chicago: 'Cieplak, Marek, Sławomir Filipek, Harald L Janovjak, and Krystiana Krzysko.
“Pulling Single Bacteriorhodopsin out of a Membrane: Comparison of Simulation
and Experiment.” Biochimica et Biophysica Acta (BBA) - Biomembranes. Elsevier,
2006. https://doi.org/10.1016/j.bbamem.2006.03.028.'
ieee: 'M. Cieplak, S. Filipek, H. L. Janovjak, and K. Krzysko, “Pulling single bacteriorhodopsin
out of a membrane: Comparison of simulation and experiment,” Biochimica et
Biophysica Acta (BBA) - Biomembranes, vol. 1758, no. 4. Elsevier, pp. 537–544,
2006.'
ista: 'Cieplak M, Filipek S, Janovjak HL, Krzysko K. 2006. Pulling single bacteriorhodopsin
out of a membrane: Comparison of simulation and experiment. Biochimica et Biophysica
Acta (BBA) - Biomembranes. 1758(4), 537–544.'
mla: 'Cieplak, Marek, et al. “Pulling Single Bacteriorhodopsin out of a Membrane:
Comparison of Simulation and Experiment.” Biochimica et Biophysica Acta (BBA)
- Biomembranes, vol. 1758, no. 4, Elsevier, 2006, pp. 537–44, doi:10.1016/j.bbamem.2006.03.028.'
short: M. Cieplak, S. Filipek, H.L. Janovjak, K. Krzysko, Biochimica et Biophysica
Acta (BBA) - Biomembranes 1758 (2006) 537–544.
date_created: 2018-12-11T12:04:50Z
date_published: 2006-04-01T00:00:00Z
date_updated: 2021-01-12T07:51:46Z
day: '01'
doi: 10.1016/j.bbamem.2006.03.028
extern: 1
intvolume: ' 1758'
issue: '4'
month: '04'
page: 537 - 544
publication: Biochimica et Biophysica Acta (BBA) - Biomembranes
publication_status: published
publisher: Elsevier
publist_id: '2502'
quality_controlled: 0
status: public
title: 'Pulling single bacteriorhodopsin out of a membrane: Comparison of simulation
and experiment'
type: journal_article
volume: 1758
year: '2006'
...
---
_id: '3729'
abstract:
- lang: eng
text: Measuring the visco-elastic properties of biological macromolecules constitutes
an important step towards the understanding of dynamic biological processes, such
as cell adhesion, muscle function, or plant cell wall stability. Force spectroscopy
techniques based on the atomic force microscope (AFM) are increasingly used to
study the complex visco-elastic response of (bio-)molecules on a single-molecule
level. These experiments either require that the AFM cantilever is actively oscillated
or that the molecule is clamped at constant force to monitor thermal cantilever
motion. Here we demonstrate that the visco-elasticity of single bio-molecules
can readily be extracted from the Brownian cantilever motion during conventional
force-extension measurements. It is shown that the characteristics of the cantilever
determine the signal-to-noise (S/N) ratio and time resolution. Using a small cantilever,
the visco-elastic properties of single dextran molecules were resolved with a
time resolution of 8.3 ms. The presented approach can be directly applied to probe
the dynamic response of complex bio-molecular systems or proteins in force-extension
experiments.
author:
- first_name: Christian
full_name: Bippes, Christian A
last_name: Bippes
- first_name: Andrew
full_name: Humphris, Andrew D
last_name: Humphris
- first_name: Martin
full_name: Stark, Martin
last_name: Stark
- first_name: Daniel
full_name: Mueller, Daniel J
last_name: Mueller
- first_name: Harald L
full_name: Harald Janovjak
id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
last_name: Janovjak
orcid: 0000-0002-8023-9315
citation:
ama: Bippes C, Humphris A, Stark M, Mueller D, Janovjak HL. Direct measurement of
single-molecule visco-elasticity in atomic force microscope force-extension experiments.
European Biophysics Journal. 2006;35(3):287-292. doi:10.1007/s00249-005-0023-9
apa: Bippes, C., Humphris, A., Stark, M., Mueller, D., & Janovjak, H. L. (2006).
Direct measurement of single-molecule visco-elasticity in atomic force microscope
force-extension experiments. European Biophysics Journal. Springer. https://doi.org/10.1007/s00249-005-0023-9
chicago: Bippes, Christian, Andrew Humphris, Martin Stark, Daniel Mueller, and Harald
L Janovjak. “Direct Measurement of Single-Molecule Visco-Elasticity in Atomic
Force Microscope Force-Extension Experiments.” European Biophysics Journal.
Springer, 2006. https://doi.org/10.1007/s00249-005-0023-9.
ieee: C. Bippes, A. Humphris, M. Stark, D. Mueller, and H. L. Janovjak, “Direct
measurement of single-molecule visco-elasticity in atomic force microscope force-extension
experiments,” European Biophysics Journal, vol. 35, no. 3. Springer, pp.
287–292, 2006.
ista: Bippes C, Humphris A, Stark M, Mueller D, Janovjak HL. 2006. Direct measurement
of single-molecule visco-elasticity in atomic force microscope force-extension
experiments. European Biophysics Journal. 35(3), 287–292.
mla: Bippes, Christian, et al. “Direct Measurement of Single-Molecule Visco-Elasticity
in Atomic Force Microscope Force-Extension Experiments.” European Biophysics
Journal, vol. 35, no. 3, Springer, 2006, pp. 287–92, doi:10.1007/s00249-005-0023-9.
short: C. Bippes, A. Humphris, M. Stark, D. Mueller, H.L. Janovjak, European Biophysics
Journal 35 (2006) 287–292.
date_created: 2018-12-11T12:04:51Z
date_published: 2006-02-01T00:00:00Z
date_updated: 2021-01-12T07:51:46Z
day: '01'
doi: 10.1007/s00249-005-0023-9
extern: 1
intvolume: ' 35'
issue: '3'
month: '02'
page: 287 - 292
publication: European Biophysics Journal
publication_status: published
publisher: Springer
publist_id: '2500'
quality_controlled: 0
status: public
title: Direct measurement of single-molecule visco-elasticity in atomic force microscope
force-extension experiments
type: journal_article
volume: 35
year: '2006'
...
---
_id: '3750'
abstract:
- lang: eng
text: We applied a single-cell assay to characterize how transcription dynamics
affects protein expression levels of a tetracycline-inducible gene expression
system. Transcriptional activity of the tetracycline promoter in response to a
steady level of inducer is steady in ΔacrAB efflux mutant but pulsating in wildtype
Escherichia coli cells. We found that the expression level of the green fluorescent
protein is several folds higher in ΔacrAB efflux mutant than in wildtype cells.
author:
- first_name: Thuc
full_name: Le,Thuc T.
last_name: Le
- first_name: Calin C
full_name: Calin Guet
id: 47F8433E-F248-11E8-B48F-1D18A9856A87
last_name: Guet
orcid: 0000-0001-6220-2052
- first_name: Philippe
full_name: Cluzel,Philippe
last_name: Cluzel
citation:
ama: Le T, Guet CC, Cluzel P. Protein expression enhancement in efflux-deleted mutant
bacteria. Protein Expression and Purification. 2006;48(1):28-31.
apa: Le, T., Guet, C. C., & Cluzel, P. (2006). Protein expression enhancement
in efflux-deleted mutant bacteria. Protein Expression and Purification.
Elsevier.
chicago: Le, Thuc, Calin C Guet, and Philippe Cluzel. “Protein Expression Enhancement
in Efflux-Deleted Mutant Bacteria.” Protein Expression and Purification.
Elsevier, 2006.
ieee: T. Le, C. C. Guet, and P. Cluzel, “Protein expression enhancement in efflux-deleted
mutant bacteria,” Protein Expression and Purification, vol. 48, no. 1.
Elsevier, pp. 28–31, 2006.
ista: Le T, Guet CC, Cluzel P. 2006. Protein expression enhancement in efflux-deleted
mutant bacteria. Protein Expression and Purification. 48(1), 28–31.
mla: Le, Thuc, et al. “Protein Expression Enhancement in Efflux-Deleted Mutant Bacteria.”
Protein Expression and Purification, vol. 48, no. 1, Elsevier, 2006, pp.
28–31.
short: T. Le, C.C. Guet, P. Cluzel, Protein Expression and Purification 48 (2006)
28–31.
date_created: 2018-12-11T12:04:58Z
date_published: 2006-07-01T00:00:00Z
date_updated: 2021-01-12T07:51:56Z
day: '01'
extern: 1
intvolume: ' 48'
issue: '1'
month: '07'
page: 28 - 31
publication: Protein Expression and Purification
publication_status: published
publisher: Elsevier
publist_id: '2478'
quality_controlled: 0
status: public
title: Protein expression enhancement in efflux-deleted mutant bacteria
type: journal_article
volume: 48
year: '2006'
...
---
_id: '3755'
abstract:
- lang: eng
text: A primitive example of adaptation in gene expression is the balance between
the rate of synthesis and degradation of cellular RNA, which allows rapid responses
to environmental signals. Here, we investigate how multidrug efflux pump systems
mediate the dynamics of a simple drug-inducible system in response to a steady
level of inducer. Using fluorescence correlation spectroscopy, we measured in
real time within a single bacterium the transcription activity at the RNA level
of the acrAB-TolC multidrug efflux pump system. When cells are exposed to constant
level of anhydrotetracycline inducer and are adsorbed onto a poly-L-lysine-coated
surface, we found that the acrAB-TolC promoter is steadily active. We also monitored
the activity of the tet promoter to characterize the effect of this efflux system
on the dynamics of drug-inducible transcription. We found that the transcriptional
response of the tet promoter to a steady level of aTc rises and then falls back
to its preinduction level. The rate of RNA degradation was constant throughout
the transcriptional pulse, indicating that the modulation of intracellular inducer
concentration alone can produce this pulsating response. Single-cell experiments
together with numerical simulations suggest that such pulsating response in drug-inducible
genetic systems is a property emerging from the dependence of drug-inducible transcription
on multidrug efflux systems.
author:
- first_name: Thuc
full_name: Le,Thuc T.
last_name: Le
- first_name: Thierry
full_name: Emonet,Thierry
last_name: Emonet
- first_name: Sébastien
full_name: Harlepp, Sébastien
last_name: Harlepp
- first_name: Calin C
full_name: Calin Guet
id: 47F8433E-F248-11E8-B48F-1D18A9856A87
last_name: Guet
orcid: 0000-0001-6220-2052
- first_name: Philippe
full_name: Cluzel,Philippe
last_name: Cluzel
citation:
ama: Le T, Emonet T, Harlepp S, Guet CC, Cluzel P. Dynamical determinants of drug-inducible
gene expression in a single bacterium. Biophysical Journal. 2006;90(9):3315-3321.
doi:10.1529/biophysj.105.073353
apa: Le, T., Emonet, T., Harlepp, S., Guet, C. C., & Cluzel, P. (2006). Dynamical
determinants of drug-inducible gene expression in a single bacterium. Biophysical
Journal. Biophysical Society. https://doi.org/10.1529/biophysj.105.073353
chicago: Le, Thuc, Thierry Emonet, Sébastien Harlepp, Calin C Guet, and Philippe
Cluzel. “Dynamical Determinants of Drug-Inducible Gene Expression in a Single
Bacterium.” Biophysical Journal. Biophysical Society, 2006. https://doi.org/10.1529/biophysj.105.073353.
ieee: T. Le, T. Emonet, S. Harlepp, C. C. Guet, and P. Cluzel, “Dynamical determinants
of drug-inducible gene expression in a single bacterium,” Biophysical Journal,
vol. 90, no. 9. Biophysical Society, pp. 3315–3321, 2006.
ista: Le T, Emonet T, Harlepp S, Guet CC, Cluzel P. 2006. Dynamical determinants
of drug-inducible gene expression in a single bacterium. Biophysical Journal.
90(9), 3315–3321.
mla: Le, Thuc, et al. “Dynamical Determinants of Drug-Inducible Gene Expression
in a Single Bacterium.” Biophysical Journal, vol. 90, no. 9, Biophysical
Society, 2006, pp. 3315–21, doi:10.1529/biophysj.105.073353.
short: T. Le, T. Emonet, S. Harlepp, C.C. Guet, P. Cluzel, Biophysical Journal 90
(2006) 3315–3321.
date_created: 2018-12-11T12:04:59Z
date_published: 2006-01-01T00:00:00Z
date_updated: 2021-01-12T07:51:58Z
day: '01'
doi: 10.1529/biophysj.105.073353
extern: 1
intvolume: ' 90'
issue: '9'
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1432126/
month: '01'
oa: 1
page: 3315 - 3321
publication: Biophysical Journal
publication_status: published
publisher: Biophysical Society
publist_id: '2472'
quality_controlled: 0
status: public
title: Dynamical determinants of drug-inducible gene expression in a single bacterium
type: journal_article
volume: 90
year: '2006'
...