---
_id: '844'
abstract:
- lang: eng
text: Mutation rate varies greatly between nucleotide sites of the human genome
and depends both on the global genomic location and the local sequence context
of a site. In particular, CpG context elevates the mutation rate by an order of
magnitude. Mutations also vary widely in their effect on the molecular function,
phenotype, and fitness. Independence of the probability of occurrence of a new
mutation's effect has been a fundamental premise in genetics. However, highly
mutable contexts may be preserved by negative selection at important sites but
destroyed by mutation at sites under no selection. Thus, there may be a positive
correlation between the rate of mutations at a nucleotide site and the magnitude
of their effect on fitness. We studied the impact of CpG context on the rate of
human-chimpanzee divergence and on intrahuman nucleotide diversity at non-synonymous
coding sites. We compared nucleotides that occupy identical positions within codons
of identical amino acids and only differ by being within versus outside CpG context.
Nucleotides within CpG context are under a stronger negative selection, as revealed
by their lower, proportionally to the mutation rate, rate of evolution and nucleotide
diversity. In particular, the probability of fixation of a non-synonymous transition
at a CpG site is two times lower than at a CpG site. Thus, sites with different
mutation rates are not necessarily selectively equivalent. This suggests that
the mutation rate may complement sequence conservation as a characteristic predictive
of functional importance of nucleotide sites.
acknowledgement: This work was supported in part by NIH grants R01 GM078598 and U54
LM008748.
author:
- first_name: Steffen
full_name: Schmidt, Steffen
last_name: Schmidt
- first_name: Anna
full_name: Gerasimova, Anna
last_name: Gerasimova
- first_name: Fyodor
full_name: Fyodor Kondrashov
id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
last_name: Kondrashov
orcid: 0000-0001-8243-4694
- first_name: Ivan
full_name: Adzuhbei, Ivan A
last_name: Adzuhbei
- first_name: Alexey
full_name: Kondrashov, Alexey S
last_name: Kondrashov
- first_name: Shamil
full_name: Sunyaev, Shamil R
last_name: Sunyaev
citation:
ama: Schmidt S, Gerasimova A, Kondrashov F, Adzuhbei I, Kondrashov A, Sunyaev S.
Hypermutable non-synonymous sites are under stronger negative selection. PLoS
Genetics. 2008;4(11). doi:10.1371/journal.pgen.1000281
apa: Schmidt, S., Gerasimova, A., Kondrashov, F., Adzuhbei, I., Kondrashov, A.,
& Sunyaev, S. (2008). Hypermutable non-synonymous sites are under stronger
negative selection. PLoS Genetics. Public Library of Science. https://doi.org/10.1371/journal.pgen.1000281
chicago: Schmidt, Steffen, Anna Gerasimova, Fyodor Kondrashov, Ivan Adzuhbei, Alexey
Kondrashov, and Shamil Sunyaev. “Hypermutable Non-Synonymous Sites Are under Stronger
Negative Selection.” PLoS Genetics. Public Library of Science, 2008. https://doi.org/10.1371/journal.pgen.1000281.
ieee: S. Schmidt, A. Gerasimova, F. Kondrashov, I. Adzuhbei, A. Kondrashov, and
S. Sunyaev, “Hypermutable non-synonymous sites are under stronger negative selection,”
PLoS Genetics, vol. 4, no. 11. Public Library of Science, 2008.
ista: Schmidt S, Gerasimova A, Kondrashov F, Adzuhbei I, Kondrashov A, Sunyaev S.
2008. Hypermutable non-synonymous sites are under stronger negative selection.
PLoS Genetics. 4(11).
mla: Schmidt, Steffen, et al. “Hypermutable Non-Synonymous Sites Are under Stronger
Negative Selection.” PLoS Genetics, vol. 4, no. 11, Public Library of Science,
2008, doi:10.1371/journal.pgen.1000281.
short: S. Schmidt, A. Gerasimova, F. Kondrashov, I. Adzuhbei, A. Kondrashov, S.
Sunyaev, PLoS Genetics 4 (2008).
date_created: 2018-12-11T11:48:48Z
date_published: 2008-11-01T00:00:00Z
date_updated: 2021-01-12T08:19:16Z
day: '01'
doi: 10.1371/journal.pgen.1000281
extern: 1
intvolume: ' 4'
issue: '11'
month: '11'
publication: PLoS Genetics
publication_status: published
publisher: Public Library of Science
publist_id: '6800'
quality_controlled: 0
status: public
title: Hypermutable non-synonymous sites are under stronger negative selection
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
volume: 4
year: '2008'
...
---
_id: '8480'
abstract:
- lang: eng
text: The KIX domain of the transcription co-activator CBP is a three-helix bundle
protein that folds via rapid accumulation of an intermediate state, followed by
a slower folding phase. Recent NMR relaxation dispersion studies revealed the
presence of a low-populated (excited) state of KIX that exists in equilibrium
with the natively folded form under non-denaturing conditions, and likely represents
the equilibrium analog of the folding intermediate. Here, we combine amide hydrogen/deuterium
exchange measurements using rapid NMR data acquisition techniques with backbone
15N and 13C relaxation dispersion experiments to further investigate the equilibrium
folding of the KIX domain. Residual structure within the folding intermediate
is detected by both methods, and their combination enables reliable quantification
of the amount of persistent residual structure. Three well-defined folding subunits
are found, which display variable stability and correspond closely to the individual
helices in the native state. While two of the three helices (α2 and α3) are partially
formed in the folding intermediate (to ∼ 50% and ∼ 80%, respectively, at 20 °C),
the third helix is disordered. The observed helical content within the excited
state exceeds the helical propensities predicted for the corresponding peptide
regions, suggesting that the two helices are weakly mutually stabilized, while
methyl 13C relaxation dispersion data indicate that a defined packing arrangement
is unlikely. Temperature-dependent experiments reveal that the largest enthalpy
and entropy changes along the folding reaction occur during the final transition
from the intermediate to the native state. Our experimental data are consistent
with a folding mechanism where helices α2 and α3 form rapidly, although to different
extents, while helix α1 consolidates only as folding proceeds to complete the
native state-structure.
article_processing_charge: No
article_type: original
author:
- first_name: Paul
full_name: Schanda, Paul
id: 7B541462-FAF6-11E9-A490-E8DFE5697425
last_name: Schanda
orcid: 0000-0002-9350-7606
- first_name: Bernhard
full_name: Brutscher, Bernhard
last_name: Brutscher
- first_name: Robert
full_name: Konrat, Robert
last_name: Konrat
- first_name: Martin
full_name: Tollinger, Martin
last_name: Tollinger
citation:
ama: 'Schanda P, Brutscher B, Konrat R, Tollinger M. Folding of the KIX domain:
Characterization of the equilibrium analog of a folding intermediate using 15N/13C
relaxation dispersion and fast 1H/2H amide exchange NMR spectroscopy. Journal
of Molecular Biology. 2008;380(4):726-741. doi:10.1016/j.jmb.2008.05.040'
apa: 'Schanda, P., Brutscher, B., Konrat, R., & Tollinger, M. (2008). Folding
of the KIX domain: Characterization of the equilibrium analog of a folding intermediate
using 15N/13C relaxation dispersion and fast 1H/2H amide exchange NMR spectroscopy.
Journal of Molecular Biology. Elsevier. https://doi.org/10.1016/j.jmb.2008.05.040'
chicago: 'Schanda, Paul, Bernhard Brutscher, Robert Konrat, and Martin Tollinger.
“Folding of the KIX Domain: Characterization of the Equilibrium Analog of a Folding
Intermediate Using 15N/13C Relaxation Dispersion and Fast 1H/2H Amide Exchange
NMR Spectroscopy.” Journal of Molecular Biology. Elsevier, 2008. https://doi.org/10.1016/j.jmb.2008.05.040.'
ieee: 'P. Schanda, B. Brutscher, R. Konrat, and M. Tollinger, “Folding of the KIX
domain: Characterization of the equilibrium analog of a folding intermediate using
15N/13C relaxation dispersion and fast 1H/2H amide exchange NMR spectroscopy,”
Journal of Molecular Biology, vol. 380, no. 4. Elsevier, pp. 726–741, 2008.'
ista: 'Schanda P, Brutscher B, Konrat R, Tollinger M. 2008. Folding of the KIX domain:
Characterization of the equilibrium analog of a folding intermediate using 15N/13C
relaxation dispersion and fast 1H/2H amide exchange NMR spectroscopy. Journal
of Molecular Biology. 380(4), 726–741.'
mla: 'Schanda, Paul, et al. “Folding of the KIX Domain: Characterization of the
Equilibrium Analog of a Folding Intermediate Using 15N/13C Relaxation Dispersion
and Fast 1H/2H Amide Exchange NMR Spectroscopy.” Journal of Molecular Biology,
vol. 380, no. 4, Elsevier, 2008, pp. 726–41, doi:10.1016/j.jmb.2008.05.040.'
short: P. Schanda, B. Brutscher, R. Konrat, M. Tollinger, Journal of Molecular Biology
380 (2008) 726–741.
date_created: 2020-09-18T10:12:29Z
date_published: 2008-07-18T00:00:00Z
date_updated: 2021-01-12T08:19:34Z
day: '18'
doi: 10.1016/j.jmb.2008.05.040
extern: '1'
intvolume: ' 380'
issue: '4'
keyword:
- Molecular Biology
language:
- iso: eng
month: '07'
oa_version: None
page: 726-741
publication: Journal of Molecular Biology
publication_identifier:
issn:
- 0022-2836
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: 'Folding of the KIX domain: Characterization of the equilibrium analog of a
folding intermediate using 15N/13C relaxation dispersion and fast 1H/2H amide exchange
NMR spectroscopy'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 380
year: '2008'
...
---
_id: '8481'
abstract:
- lang: eng
text: 'The copK gene is localized on the pMOL30 plasmid of Cupriavidus metallidurans
CH34 within the complex cop cluster of genes, for which 21 genes have been identified.
The expression of the corresponding periplasmic CopK protein is strongly upregulated
in the presence of copper, leading to a high periplasmic accumulation. The structure
and metal-binding properties of CopK were investigated by NMR and mass spectrometry.
The protein is dimeric in the apo state with a dissociation constant in the range
of 10- 5 M estimated from analytical ultracentrifugation. Mass spectrometry revealed
that CopK has two high-affinity Cu(I)-binding sites per monomer with different
Cu(I) affinities. Binding of Cu(II) was observed but appeared to be non-specific.
The solution structure of apo-CopK revealed an all-β fold formed of two β-sheets
in perpendicular orientation with an unstructured C-terminal tail. The dimer interface
is formed by the surface of the C-terminal β-sheet. Binding of the first Cu(I)-ion
induces a major structural modification involving dissociation of the dimeric
apo-protein. Backbone chemical shifts determined for the 1Cu(I)-bound form confirm
the conservation of the N-terminal β-sheet, while the last strand of the C-terminal
sheet appears in slow conformational exchange. We hypothesize that the partial
disruption of the C-terminal β-sheet is related to dimer dissociation. NH-exchange
data acquired on the apo-protein are consistent with a lower thermodynamic stability
of the C-terminal sheet. CopK contains seven methionine residues, five of which
appear highly conserved. Chemical shift data suggest implication of two or three
methionines (Met54, Met38, Met28) in the first Cu(I) site. Addition of a second
Cu(I) ion further increases protein plasticity. Comparison of the structural and
metal-binding properties of CopK with other periplasmic copper-binding proteins
reveals two conserved features within these functionally related proteins: the
all-β fold and the methionine-rich Cu(I)-binding site.'
article_processing_charge: No
article_type: original
author:
- first_name: Beate
full_name: Bersch, Beate
last_name: Bersch
- first_name: Adrien
full_name: Favier, Adrien
last_name: Favier
- first_name: Paul
full_name: Schanda, Paul
id: 7B541462-FAF6-11E9-A490-E8DFE5697425
last_name: Schanda
orcid: 0000-0002-9350-7606
- first_name: Sébastien
full_name: van Aelst, Sébastien
last_name: van Aelst
- first_name: Tatiana
full_name: Vallaeys, Tatiana
last_name: Vallaeys
- first_name: Jacques
full_name: Covès, Jacques
last_name: Covès
- first_name: Max
full_name: Mergeay, Max
last_name: Mergeay
- first_name: Ruddy
full_name: Wattiez, Ruddy
last_name: Wattiez
citation:
ama: Bersch B, Favier A, Schanda P, et al. Molecular structure and metal-binding
properties of the periplasmic CopK protein expressed in Cupriavidus metallidurans
CH34 during copper challenge. Journal of Molecular Biology. 2008;380(2):386-403.
doi:10.1016/j.jmb.2008.05.017
apa: Bersch, B., Favier, A., Schanda, P., van Aelst, S., Vallaeys, T., Covès, J.,
… Wattiez, R. (2008). Molecular structure and metal-binding properties of the
periplasmic CopK protein expressed in Cupriavidus metallidurans CH34 during copper
challenge. Journal of Molecular Biology. Elsevier. https://doi.org/10.1016/j.jmb.2008.05.017
chicago: Bersch, Beate, Adrien Favier, Paul Schanda, Sébastien van Aelst, Tatiana
Vallaeys, Jacques Covès, Max Mergeay, and Ruddy Wattiez. “Molecular Structure
and Metal-Binding Properties of the Periplasmic CopK Protein Expressed in Cupriavidus
Metallidurans CH34 during Copper Challenge.” Journal of Molecular Biology.
Elsevier, 2008. https://doi.org/10.1016/j.jmb.2008.05.017.
ieee: B. Bersch et al., “Molecular structure and metal-binding properties
of the periplasmic CopK protein expressed in Cupriavidus metallidurans CH34 during
copper challenge,” Journal of Molecular Biology, vol. 380, no. 2. Elsevier,
pp. 386–403, 2008.
ista: Bersch B, Favier A, Schanda P, van Aelst S, Vallaeys T, Covès J, Mergeay M,
Wattiez R. 2008. Molecular structure and metal-binding properties of the periplasmic
CopK protein expressed in Cupriavidus metallidurans CH34 during copper challenge.
Journal of Molecular Biology. 380(2), 386–403.
mla: Bersch, Beate, et al. “Molecular Structure and Metal-Binding Properties of
the Periplasmic CopK Protein Expressed in Cupriavidus Metallidurans CH34 during
Copper Challenge.” Journal of Molecular Biology, vol. 380, no. 2, Elsevier,
2008, pp. 386–403, doi:10.1016/j.jmb.2008.05.017.
short: B. Bersch, A. Favier, P. Schanda, S. van Aelst, T. Vallaeys, J. Covès, M.
Mergeay, R. Wattiez, Journal of Molecular Biology 380 (2008) 386–403.
date_created: 2020-09-18T10:12:37Z
date_published: 2008-07-04T00:00:00Z
date_updated: 2021-01-12T08:19:34Z
day: '04'
doi: 10.1016/j.jmb.2008.05.017
extern: '1'
intvolume: ' 380'
issue: '2'
keyword:
- Molecular Biology
language:
- iso: eng
month: '07'
oa_version: None
page: 386-403
publication: Journal of Molecular Biology
publication_identifier:
issn:
- 0022-2836
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Molecular structure and metal-binding properties of the periplasmic CopK protein
expressed in Cupriavidus metallidurans CH34 during copper challenge
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 380
year: '2008'
...
---
_id: '8482'
abstract:
- lang: eng
text: The SOFAST-HMQC experiment [P. Schanda, B. Brutscher, Very fast two-dimensional
NMR spectroscopy for real-time investigation of dynamic events in proteins on
the time scale of seconds, J. Am. Chem. Soc. 127 (2005) 8014–8015] allows recording
two-dimensional correlation spectra of macromolecules such as proteins in only
a few seconds acquisition time. To achieve the highest possible sensitivity, SOFAST-HMQC
experiments are preferably performed on high-field NMR spectrometers equipped
with cryogenically cooled probes. The duty cycle of over 80% in fast-pulsing SOFAST-HMQC
experiments, however, may cause problems when using a cryogenic probe. Here we
introduce SE-IPAP-SOFAST-HMQC, a new pulse sequence that provides comparable sensitivity
to standard SOFAST-HMQC, while avoiding heteronuclear decoupling during 1H detection,
and thus significantly reducing the radiofrequency load of the probe during the
experiment. The experiment is also attractive for fast and sensitive measurement
of heteronuclear one-bond spin coupling constants.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Thomas
full_name: Kern, Thomas
last_name: Kern
- first_name: Paul
full_name: Schanda, Paul
id: 7B541462-FAF6-11E9-A490-E8DFE5697425
last_name: Schanda
orcid: 0000-0002-9350-7606
- first_name: Bernhard
full_name: Brutscher, Bernhard
last_name: Brutscher
citation:
ama: Kern T, Schanda P, Brutscher B. Sensitivity-enhanced IPAP-SOFAST-HMQC for fast-pulsing
2D NMR with reduced radiofrequency load. Journal of Magnetic Resonance.
2008;190(2):333-338. doi:10.1016/j.jmr.2007.11.015
apa: Kern, T., Schanda, P., & Brutscher, B. (2008). Sensitivity-enhanced IPAP-SOFAST-HMQC
for fast-pulsing 2D NMR with reduced radiofrequency load. Journal of Magnetic
Resonance. Elsevier. https://doi.org/10.1016/j.jmr.2007.11.015
chicago: Kern, Thomas, Paul Schanda, and Bernhard Brutscher. “Sensitivity-Enhanced
IPAP-SOFAST-HMQC for Fast-Pulsing 2D NMR with Reduced Radiofrequency Load.” Journal
of Magnetic Resonance. Elsevier, 2008. https://doi.org/10.1016/j.jmr.2007.11.015.
ieee: T. Kern, P. Schanda, and B. Brutscher, “Sensitivity-enhanced IPAP-SOFAST-HMQC
for fast-pulsing 2D NMR with reduced radiofrequency load,” Journal of Magnetic
Resonance, vol. 190, no. 2. Elsevier, pp. 333–338, 2008.
ista: Kern T, Schanda P, Brutscher B. 2008. Sensitivity-enhanced IPAP-SOFAST-HMQC
for fast-pulsing 2D NMR with reduced radiofrequency load. Journal of Magnetic
Resonance. 190(2), 333–338.
mla: Kern, Thomas, et al. “Sensitivity-Enhanced IPAP-SOFAST-HMQC for Fast-Pulsing
2D NMR with Reduced Radiofrequency Load.” Journal of Magnetic Resonance,
vol. 190, no. 2, Elsevier, 2008, pp. 333–38, doi:10.1016/j.jmr.2007.11.015.
short: T. Kern, P. Schanda, B. Brutscher, Journal of Magnetic Resonance 190 (2008)
333–338.
date_created: 2020-09-18T10:12:46Z
date_published: 2008-02-01T00:00:00Z
date_updated: 2021-01-12T08:19:35Z
day: '01'
doi: 10.1016/j.jmr.2007.11.015
extern: '1'
intvolume: ' 190'
issue: '2'
keyword:
- Nuclear and High Energy Physics
- Biophysics
- Biochemistry
- Condensed Matter Physics
language:
- iso: eng
month: '02'
oa_version: None
page: 333-338
publication: Journal of Magnetic Resonance
publication_identifier:
issn:
- 1090-7807
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Sensitivity-enhanced IPAP-SOFAST-HMQC for fast-pulsing 2D NMR with reduced
radiofrequency load
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 190
year: '2008'
...
---
_id: '8509'
abstract:
- lang: eng
text: The goal of this paper is to present to nonspecialists what is perhaps the
simplest possible geometrical picture explaining the mechanism of Arnold diffusion.
We choose to speak of a specific model—that of geometric rays in a periodic optical
medium. This model is equivalent to that of a particle in a periodic potential
in ${\mathbb R}^{n}$ with energy prescribed and to the geodesic flow in a Riemannian
metric on ${\mathbb R}^{n} $.
article_processing_charge: No
article_type: original
author:
- first_name: Vadim
full_name: Kaloshin, Vadim
id: FE553552-CDE8-11E9-B324-C0EBE5697425
last_name: Kaloshin
orcid: 0000-0002-6051-2628
- first_name: Mark
full_name: Levi, Mark
last_name: Levi
citation:
ama: Kaloshin V, Levi M. Geometry of Arnold diffusion. SIAM Review. 2008;50(4):702-720.
doi:10.1137/070703235
apa: Kaloshin, V., & Levi, M. (2008). Geometry of Arnold diffusion. SIAM
Review. Society for Industrial & Applied Mathematics. https://doi.org/10.1137/070703235
chicago: Kaloshin, Vadim, and Mark Levi. “Geometry of Arnold Diffusion.” SIAM
Review. Society for Industrial & Applied Mathematics, 2008. https://doi.org/10.1137/070703235.
ieee: V. Kaloshin and M. Levi, “Geometry of Arnold diffusion,” SIAM Review,
vol. 50, no. 4. Society for Industrial & Applied Mathematics, pp. 702–720,
2008.
ista: Kaloshin V, Levi M. 2008. Geometry of Arnold diffusion. SIAM Review. 50(4),
702–720.
mla: Kaloshin, Vadim, and Mark Levi. “Geometry of Arnold Diffusion.” SIAM Review,
vol. 50, no. 4, Society for Industrial & Applied Mathematics, 2008, pp. 702–20,
doi:10.1137/070703235.
short: V. Kaloshin, M. Levi, SIAM Review 50 (2008) 702–720.
date_created: 2020-09-18T10:48:12Z
date_published: 2008-11-05T00:00:00Z
date_updated: 2021-01-12T08:19:46Z
day: '05'
doi: 10.1137/070703235
extern: '1'
intvolume: ' 50'
issue: '4'
keyword:
- Theoretical Computer Science
- Applied Mathematics
- Computational Mathematics
language:
- iso: eng
month: '11'
oa_version: None
page: 702-720
publication: SIAM Review
publication_identifier:
issn:
- 0036-1445
- 1095-7200
publication_status: published
publisher: Society for Industrial & Applied Mathematics
quality_controlled: '1'
status: public
title: Geometry of Arnold diffusion
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 50
year: '2008'
...
---
_id: '8510'
abstract:
- lang: eng
text: In this paper, using the ideas of Bessi and Mather, we present a simple mechanical
system exhibiting Arnold diffusion. This system of a particle in a small periodic
potential can be also interpreted as ray propagation in a periodic optical medium
with a near-constant index of refraction. Arnold diffusion in this context manifests
itself as an arbitrary finite change of direction for nearly constant index of
refraction.
article_processing_charge: No
article_type: original
author:
- first_name: Vadim
full_name: Kaloshin, Vadim
id: FE553552-CDE8-11E9-B324-C0EBE5697425
last_name: Kaloshin
orcid: 0000-0002-6051-2628
- first_name: Mark
full_name: Levi, Mark
last_name: Levi
citation:
ama: Kaloshin V, Levi M. An example of Arnold diffusion for near-integrable Hamiltonians.
Bulletin of the American Mathematical Society. 2008;45(3):409-427. doi:10.1090/s0273-0979-08-01211-1
apa: Kaloshin, V., & Levi, M. (2008). An example of Arnold diffusion for near-integrable
Hamiltonians. Bulletin of the American Mathematical Society. American Mathematical
Society. https://doi.org/10.1090/s0273-0979-08-01211-1
chicago: Kaloshin, Vadim, and Mark Levi. “An Example of Arnold Diffusion for Near-Integrable
Hamiltonians.” Bulletin of the American Mathematical Society. American
Mathematical Society, 2008. https://doi.org/10.1090/s0273-0979-08-01211-1.
ieee: V. Kaloshin and M. Levi, “An example of Arnold diffusion for near-integrable
Hamiltonians,” Bulletin of the American Mathematical Society, vol. 45,
no. 3. American Mathematical Society, pp. 409–427, 2008.
ista: Kaloshin V, Levi M. 2008. An example of Arnold diffusion for near-integrable
Hamiltonians. Bulletin of the American Mathematical Society. 45(3), 409–427.
mla: Kaloshin, Vadim, and Mark Levi. “An Example of Arnold Diffusion for Near-Integrable
Hamiltonians.” Bulletin of the American Mathematical Society, vol. 45,
no. 3, American Mathematical Society, 2008, pp. 409–27, doi:10.1090/s0273-0979-08-01211-1.
short: V. Kaloshin, M. Levi, Bulletin of the American Mathematical Society 45 (2008)
409–427.
date_created: 2020-09-18T10:48:20Z
date_published: 2008-07-01T00:00:00Z
date_updated: 2021-01-12T08:19:47Z
day: '01'
doi: 10.1090/s0273-0979-08-01211-1
extern: '1'
intvolume: ' 45'
issue: '3'
keyword:
- Applied Mathematics
- General Mathematics
language:
- iso: eng
month: '07'
oa_version: None
page: 409-427
publication: Bulletin of the American Mathematical Society
publication_identifier:
issn:
- 0273-0979
publication_status: published
publisher: American Mathematical Society
quality_controlled: '1'
status: public
title: An example of Arnold diffusion for near-integrable Hamiltonians
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 45
year: '2008'
...
---
_id: '895'
abstract:
- lang: eng
text: Background. The arginine vasopressin V1a receptor (V1aR) modulates social
cognition and behavior in a wide variety of species. Variation in a repetitive
microsatellite element in the 5′ flanking region of the V1aR gene (AVPR1A) in
rodents has been associated with variation in brain V1aR expression and in social
behavior. In humans, the 5′ flanking region of AVPR1A contains a tandem duplication
of two ∼350 bp, microsatellite-containing elements located approximately 3.5 kb
upstream of the transcription start site. The first block, referred to as DupA,
contains a polymorphic (GT) 25microsatellite; the second block, DupB, has a complex
(CT) 4-(TT)-(CT)8-(GT)24polymorphic motif, known as RS3. Polymorphisms in RS3
have been associated with variation in sociobehavioral traits in humans, including
autism spectrum disorders. Thus, evolution of these regions may have contributed
to variation in social behavior in primates. We examined the structure of these
regions in six ape, six monkey, and one prosimian species. Results. Both tandem
repeat blocks are present upstream of the AVPR1A coding region in five of the
ape species we investigated, while monkeys have only one copy of this region.
As in humans, the microsatellites within DupA and DupB are polymorphic in many
primate species. Furthermore, both single (lacking DupB) and duplicated alleles
(containing both DupA and DupB) are present in chimpanzee (Pan troglodytes) populations
with allele frequencies of 0.795 and 0.205 for the single and duplicated alleles,
respectively, based on the analysis of 47 wild-caught individuals. Finally, a
phylogenetic reconstruction suggests two alternate evolutionary histories for
this locus. Conclusion. There is no obvious relationship between the presence
of the RS3 duplication and social organization in primates. However, polymorphisms
identified in some species may be useful in future genetic association studies.
In particular, the presence of both single and duplicated alleles in chimpanzees
provides a unique opportunity to assess the functional role of this duplication
in contributing to variation in social behavior in primates. While our initial
studies show no signs of directional selection on this locus in chimps, pharmacological
and genetic association studies support a potential role for this region in influencing
V1aR expression and social behavior.
acknowledgement: |
We thank the caretakers at Zoo Atlanta and Yerkes National Primate Center for help with procuring specimens. Additional DNA samples were supplied by Bill Hopkins, Emory University (chimpanzee), Allyson Bennet, Wake Forest University (chimpanzee, rhesus macaque, bonnet macaque), Mar Sanchez, Emory University (rhesus macaque), and Anne Yoder, Duke University (galago). Susan Lambeth, M.D. Anderson Cancer Center, and Katie Chace, Yerkes National Primate Center, helped provide records regarding the origins of wild born chimps at these centers. We would like to thank Dr Lisa McGraw and two anonymous reviewers for their com- ments on this manuscript. This work was supported by NSF IBN-9876754, NIH RR00165, NIMH56897 (LJY), MH64692 (LJY) and a Howard Hughes Predoctoral Fellowship (ZRD).
author:
- first_name: Zoe
full_name: Donaldson, Zoe R
last_name: Donaldson
- first_name: Fyodor
full_name: Fyodor Kondrashov
id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
last_name: Kondrashov
orcid: 0000-0001-8243-4694
- first_name: Andrea
full_name: Putnam, Andrea S
last_name: Putnam
- first_name: Yaohui
full_name: Bai, Yaohui
last_name: Bai
- first_name: Tara
full_name: Stoinski, Tara S
last_name: Stoinski
- first_name: Elizabeth
full_name: Hammock, Elizabeth A
last_name: Hammock
- first_name: Larry
full_name: Young, Larry
last_name: Young
citation:
ama: Donaldson Z, Kondrashov F, Putnam A, et al. Evolution of a behavior-linked
microsatellite-containing element in the 5′ flanking region of the primate AVPR1A
gene. BMC Evolutionary Biology. 2008;8(1). doi:10.1186/1471-2148-8-180
apa: Donaldson, Z., Kondrashov, F., Putnam, A., Bai, Y., Stoinski, T., Hammock,
E., & Young, L. (2008). Evolution of a behavior-linked microsatellite-containing
element in the 5′ flanking region of the primate AVPR1A gene. BMC Evolutionary
Biology. BioMed Central. https://doi.org/10.1186/1471-2148-8-180
chicago: Donaldson, Zoe, Fyodor Kondrashov, Andrea Putnam, Yaohui Bai, Tara Stoinski,
Elizabeth Hammock, and Larry Young. “Evolution of a Behavior-Linked Microsatellite-Containing
Element in the 5′ Flanking Region of the Primate AVPR1A Gene.” BMC Evolutionary
Biology. BioMed Central, 2008. https://doi.org/10.1186/1471-2148-8-180.
ieee: Z. Donaldson et al., “Evolution of a behavior-linked microsatellite-containing
element in the 5′ flanking region of the primate AVPR1A gene,” BMC Evolutionary
Biology, vol. 8, no. 1. BioMed Central, 2008.
ista: Donaldson Z, Kondrashov F, Putnam A, Bai Y, Stoinski T, Hammock E, Young L.
2008. Evolution of a behavior-linked microsatellite-containing element in the
5′ flanking region of the primate AVPR1A gene. BMC Evolutionary Biology. 8(1).
mla: Donaldson, Zoe, et al. “Evolution of a Behavior-Linked Microsatellite-Containing
Element in the 5′ Flanking Region of the Primate AVPR1A Gene.” BMC Evolutionary
Biology, vol. 8, no. 1, BioMed Central, 2008, doi:10.1186/1471-2148-8-180.
short: Z. Donaldson, F. Kondrashov, A. Putnam, Y. Bai, T. Stoinski, E. Hammock,
L. Young, BMC Evolutionary Biology 8 (2008).
date_created: 2018-12-11T11:49:04Z
date_published: 2008-01-01T00:00:00Z
date_updated: 2021-01-12T08:21:29Z
day: '01'
doi: 10.1186/1471-2148-8-180
extern: 1
intvolume: ' 8'
issue: '1'
month: '01'
publication: BMC Evolutionary Biology
publication_status: published
publisher: BioMed Central
publist_id: '6753'
quality_controlled: 0
status: public
title: Evolution of a behavior-linked microsatellite-containing element in the 5′
flanking region of the primate AVPR1A gene
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
volume: 8
year: '2008'
...
---
_id: '907'
abstract:
- lang: eng
text: The most common form of protein-coding gene overlap in eukaryotes is a simple
nested structure, whereby one gene is embedded in an intron of another. Analysis
of nested protein-coding genes in vertebrates, fruit flies and nematodes revealed
substantially higher rates of evolutionary gains than losses. The accumulation
of nested gene structures could not be attributed to any obvious functional relationships
between the genes involved and represents an increase of the organizational complexity
of animal genomes via a neutral process.
author:
- first_name: Raquel
full_name: Assis, Raquel
last_name: Assis
- first_name: Alexey
full_name: Kondrashov, Alexey S
last_name: Kondrashov
- first_name: Eugene
full_name: Koonin, Eugene V
last_name: Koonin
- first_name: Fyodor
full_name: Fyodor Kondrashov
id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
last_name: Kondrashov
orcid: 0000-0001-8243-4694
citation:
ama: Assis R, Kondrashov A, Koonin E, Kondrashov F. Nested genes and increasing
organizational complexity of metazoan genomes. Trends in Genetics. 2008;24(10):475-478.
doi:10.1016/j.tig.2008.08.003
apa: Assis, R., Kondrashov, A., Koonin, E., & Kondrashov, F. (2008). Nested
genes and increasing organizational complexity of metazoan genomes. Trends
in Genetics. Elsevier. https://doi.org/10.1016/j.tig.2008.08.003
chicago: Assis, Raquel, Alexey Kondrashov, Eugene Koonin, and Fyodor Kondrashov.
“Nested Genes and Increasing Organizational Complexity of Metazoan Genomes.” Trends
in Genetics. Elsevier, 2008. https://doi.org/10.1016/j.tig.2008.08.003.
ieee: R. Assis, A. Kondrashov, E. Koonin, and F. Kondrashov, “Nested genes and increasing
organizational complexity of metazoan genomes,” Trends in Genetics, vol.
24, no. 10. Elsevier, pp. 475–478, 2008.
ista: Assis R, Kondrashov A, Koonin E, Kondrashov F. 2008. Nested genes and increasing
organizational complexity of metazoan genomes. Trends in Genetics. 24(10), 475–478.
mla: Assis, Raquel, et al. “Nested Genes and Increasing Organizational Complexity
of Metazoan Genomes.” Trends in Genetics, vol. 24, no. 10, Elsevier, 2008,
pp. 475–78, doi:10.1016/j.tig.2008.08.003.
short: R. Assis, A. Kondrashov, E. Koonin, F. Kondrashov, Trends in Genetics 24
(2008) 475–478.
date_created: 2018-12-11T11:49:08Z
date_published: 2008-10-01T00:00:00Z
date_updated: 2021-01-12T08:21:49Z
day: '01'
doi: 10.1016/j.tig.2008.08.003
extern: 1
intvolume: ' 24'
issue: '10'
month: '10'
page: 475 - 478
publication: Trends in Genetics
publication_status: published
publisher: Elsevier
publist_id: '6743'
quality_controlled: 0
status: public
title: Nested genes and increasing organizational complexity of metazoan genomes
type: journal_article
volume: 24
year: '2008'
...
---
_id: '9457'
abstract:
- lang: eng
text: Eukaryotic chromatin is separated into functional domains differentiated by
posttranslational histone modifications, histone variants, and DNA methylation1–6.
Methylation is associated with repression of transcriptional initiation in plants
and animals, and is frequently found in transposable elements. Proper methylation
patterns are critical for eukaryotic development4,5, and aberrant methylation-induced
silencing of tumor suppressor genes is a common feature of human cancer7. In contrast
to methylation, the histone variant H2A.Z is preferentially deposited by the Swr1
ATPase complex near 5′ ends of genes where it promotes transcriptional competence8–20.
How DNA methylation and H2A.Z influence transcription remains largely unknown.
Here we show that in the plant Arabidopsis thaliana, regions of DNA methylation
are quantitatively deficient in H2A.Z. Exclusion of H2A.Z is seen at sites of
DNA methylation in the bodies of actively transcribed genes and in methylated
transposons. Mutation of the MET1 DNA methyltransferase, which causes both losses
and gains of DNA methylation4,5, engenders opposite changes in H2A.Z deposition,
while mutation of the PIE1 subunit of the Swr1 complex that deposits H2A.Z17 leads
to genome-wide hypermethylation. Our findings indicate that DNA methylation can
influence chromatin structure and effect gene silencing by excluding H2A.Z, and
that H2A.Z protects genes from DNA methylation.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Daniel
full_name: Zilberman, Daniel
id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
last_name: Zilberman
orcid: 0000-0002-0123-8649
- first_name: Devin
full_name: Coleman-Derr, Devin
last_name: Coleman-Derr
- first_name: Tracy
full_name: Ballinger, Tracy
last_name: Ballinger
- first_name: Steven
full_name: Henikoff, Steven
last_name: Henikoff
citation:
ama: Zilberman D, Coleman-Derr D, Ballinger T, Henikoff S. Histone H2A.Z and DNA
methylation are mutually antagonistic chromatin marks. Nature. 2008;456(7218):125-129.
doi:10.1038/nature07324
apa: Zilberman, D., Coleman-Derr, D., Ballinger, T., & Henikoff, S. (2008).
Histone H2A.Z and DNA methylation are mutually antagonistic chromatin marks. Nature.
Springer Nature. https://doi.org/10.1038/nature07324
chicago: Zilberman, Daniel, Devin Coleman-Derr, Tracy Ballinger, and Steven Henikoff.
“Histone H2A.Z and DNA Methylation Are Mutually Antagonistic Chromatin Marks.”
Nature. Springer Nature, 2008. https://doi.org/10.1038/nature07324.
ieee: D. Zilberman, D. Coleman-Derr, T. Ballinger, and S. Henikoff, “Histone H2A.Z
and DNA methylation are mutually antagonistic chromatin marks,” Nature,
vol. 456, no. 7218. Springer Nature, pp. 125–129, 2008.
ista: Zilberman D, Coleman-Derr D, Ballinger T, Henikoff S. 2008. Histone H2A.Z
and DNA methylation are mutually antagonistic chromatin marks. Nature. 456(7218),
125–129.
mla: Zilberman, Daniel, et al. “Histone H2A.Z and DNA Methylation Are Mutually Antagonistic
Chromatin Marks.” Nature, vol. 456, no. 7218, Springer Nature, 2008, pp.
125–29, doi:10.1038/nature07324.
short: D. Zilberman, D. Coleman-Derr, T. Ballinger, S. Henikoff, Nature 456 (2008)
125–129.
date_created: 2021-06-04T11:49:32Z
date_published: 2008-11-06T00:00:00Z
date_updated: 2021-12-14T08:54:36Z
day: '06'
department:
- _id: DaZi
doi: 10.1038/nature07324
extern: '1'
external_id:
pmid:
- '18815594'
intvolume: ' 456'
issue: '7218'
keyword:
- Multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877514/
month: '11'
oa: 1
oa_version: Submitted Version
page: 125-129
pmid: 1
publication: Nature
publication_identifier:
eissn:
- 1476-4687
issn:
- 0028-0836
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Histone H2A.Z and DNA methylation are mutually antagonistic chromatin marks
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 456
year: '2008'
...
---
_id: '9537'
abstract:
- lang: eng
text: DNA methylation is an ancient process found in all domains of life. Although
the enzymes that mediate methylation have remained highly conserved, DNA methylation
has been adapted for a variety of uses throughout evolution, including defense
against transposable elements and control of gene expression. Defects in DNA methylation
are linked to human diseases, including cancer. Methylation has been lost several
times in the course of animal and fungal evolution, thus limiting the opportunity
for study in common model organisms. In the past decade, plants have emerged as
a premier model system for genetic dissection of DNA methylation. A recent combination
of plant genetics with powerful genomic approaches has led to a number of exciting
discoveries and promises many more.
article_processing_charge: No
article_type: review
author:
- first_name: Daniel
full_name: Zilberman, Daniel
id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
last_name: Zilberman
orcid: 0000-0002-0123-8649
citation:
ama: Zilberman D. The evolving functions of DNA methylation. Current Opinion
in Plant Biology. 2008;11(5):554-559. doi:10.1016/j.pbi.2008.07.004
apa: Zilberman, D. (2008). The evolving functions of DNA methylation. Current
Opinion in Plant Biology. Elsevier . https://doi.org/10.1016/j.pbi.2008.07.004
chicago: Zilberman, Daniel. “The Evolving Functions of DNA Methylation.” Current
Opinion in Plant Biology. Elsevier , 2008. https://doi.org/10.1016/j.pbi.2008.07.004.
ieee: D. Zilberman, “The evolving functions of DNA methylation,” Current Opinion
in Plant Biology, vol. 11, no. 5. Elsevier , pp. 554–559, 2008.
ista: Zilberman D. 2008. The evolving functions of DNA methylation. Current Opinion
in Plant Biology. 11(5), 554–559.
mla: Zilberman, Daniel. “The Evolving Functions of DNA Methylation.” Current
Opinion in Plant Biology, vol. 11, no. 5, Elsevier , 2008, pp. 554–59, doi:10.1016/j.pbi.2008.07.004.
short: D. Zilberman, Current Opinion in Plant Biology 11 (2008) 554–559.
date_created: 2021-06-08T13:13:37Z
date_published: 2008-10-01T00:00:00Z
date_updated: 2021-12-14T08:54:07Z
department:
- _id: DaZi
doi: 10.1016/j.pbi.2008.07.004
extern: '1'
external_id:
pmid:
- '18774331'
intvolume: ' 11'
issue: '5'
language:
- iso: eng
month: '10'
oa_version: None
page: 554-559
pmid: 1
publication: Current Opinion in Plant Biology
publication_identifier:
issn:
- 1369-5266
publication_status: published
publisher: 'Elsevier '
quality_controlled: '1'
scopus_import: '1'
status: public
title: The evolving functions of DNA methylation
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 11
year: '2008'
...
---
_id: '965'
abstract:
- lang: eng
text: We give many examples of applying Bogoliubov's forest formula to iterative
solutions of various nonlinear equations. The same formula describes an extremely
wide class of objects, from an ordinary quadratic equation to renormalization
in quantum field theory.
acknowledgement: |-
This work is supported in part by the Dynasty Foundation (M. N. S.), the
Russian Foundation for Basic Research (Grant No
s. 07-02-00878 and 07-02-00645), a joint grant (Grant
No. 06-01-92059-CE), the NWO (Project No. 047.011.2004.026), INTAS (Grant No. 05-1000008-7865), the
Program for Supporting Leading Scientific School
s (Grant No. NSh-8004.2006.2), and also by a project
(Project No. ANR-05-BLAN-0029-01, A. Yu. M.).
author:
- first_name: Alexei
full_name: Morozov, Alexei Y
last_name: Morozov
- first_name: Maksym
full_name: Maksym Serbyn
id: 47809E7E-F248-11E8-B48F-1D18A9856A87
last_name: Serbyn
orcid: 0000-0002-2399-5827
citation:
ama: Morozov A, Serbyn M. Nonlinear algebra and Bogoliubov’s recursion. Theoretical
and Mathematical Physics. 2008;154(2):270-293. doi:10.1007/s11232-008-0026-7
apa: Morozov, A., & Serbyn, M. (2008). Nonlinear algebra and Bogoliubov’s recursion.
Theoretical and Mathematical Physics. Elsevier. https://doi.org/10.1007/s11232-008-0026-7
chicago: Morozov, Alexei, and Maksym Serbyn. “Nonlinear Algebra and Bogoliubov’s
Recursion.” Theoretical and Mathematical Physics. Elsevier, 2008. https://doi.org/10.1007/s11232-008-0026-7.
ieee: A. Morozov and M. Serbyn, “Nonlinear algebra and Bogoliubov’s recursion,”
Theoretical and Mathematical Physics, vol. 154, no. 2. Elsevier, pp. 270–293,
2008.
ista: Morozov A, Serbyn M. 2008. Nonlinear algebra and Bogoliubov’s recursion. Theoretical
and Mathematical Physics. 154(2), 270–293.
mla: Morozov, Alexei, and Maksym Serbyn. “Nonlinear Algebra and Bogoliubov’s Recursion.”
Theoretical and Mathematical Physics, vol. 154, no. 2, Elsevier, 2008,
pp. 270–93, doi:10.1007/s11232-008-0026-7.
short: A. Morozov, M. Serbyn, Theoretical and Mathematical Physics 154 (2008) 270–293.
date_created: 2018-12-11T11:49:26Z
date_published: 2008-01-01T00:00:00Z
date_updated: 2021-01-12T08:22:17Z
day: '01'
doi: 10.1007/s11232-008-0026-7
extern: 1
intvolume: ' 154'
issue: '2'
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/hep-th/0703258
month: '01'
oa: 1
page: 270 - 293
publication: Theoretical and Mathematical Physics
publication_status: published
publisher: Elsevier
publist_id: '6437'
quality_controlled: 0
status: public
title: Nonlinear algebra and Bogoliubov's recursion
type: journal_article
volume: 154
year: '2008'
...
---
_id: '7320'
abstract:
- lang: eng
text: A comparative, experimental diffusivity study of gas diffusion layer (GDL)
materials for polymer electrolyte fuel cells (PEFC) is presented for the first
time. The GDL plays an important role for electrochemical losses due to gas transport
limitations at high current densities. Characterization and optimization of these
layers is therefore essential to improve power density. A recently developed method
which allows for fast diffusimetry is applied and data compared to the literature
values. Measurements are made as a function of direction and compression and the
effect of different binder structures and hydrophobic treatments on effective
diffusivities are discussed. A better understanding of the results is gained by
including novel GDL cross-section images and a meaningful unit cell model for
the interpretation of the data. The diffusivity data is valuable for GDL manufacturers
and future PEFC models. The study reveals that a binder–fiber ratio larger than
50% has a negative impact on the effective diffusion properties. The hydrophobic
treatment which is necessary to improve the water management can impede diffusion
and thus reduce the power density. Furthermore binder has an isotropic effect
while compression pronounces the in-plane orientation of the fibers.
article_processing_charge: No
article_type: original
author:
- first_name: Reto
full_name: Flückiger, Reto
last_name: Flückiger
- first_name: Stefan Alexander
full_name: Freunberger, Stefan Alexander
id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
last_name: Freunberger
orcid: 0000-0003-2902-5319
- first_name: Denis
full_name: Kramer, Denis
last_name: Kramer
- first_name: Alexander
full_name: Wokaun, Alexander
last_name: Wokaun
- first_name: Günther G.
full_name: Scherer, Günther G.
last_name: Scherer
- first_name: Felix N.
full_name: Büchi, Felix N.
last_name: Büchi
citation:
ama: Flückiger R, Freunberger SA, Kramer D, Wokaun A, Scherer GG, Büchi FN. Anisotropic,
effective diffusivity of porous gas diffusion layer materials for PEFC. Electrochimica
Acta. 2008;54(2):551-559. doi:10.1016/j.electacta.2008.07.034
apa: Flückiger, R., Freunberger, S. A., Kramer, D., Wokaun, A., Scherer, G. G.,
& Büchi, F. N. (2008). Anisotropic, effective diffusivity of porous gas diffusion
layer materials for PEFC. Electrochimica Acta. Elsevier. https://doi.org/10.1016/j.electacta.2008.07.034
chicago: Flückiger, Reto, Stefan Alexander Freunberger, Denis Kramer, Alexander
Wokaun, Günther G. Scherer, and Felix N. Büchi. “Anisotropic, Effective Diffusivity
of Porous Gas Diffusion Layer Materials for PEFC.” Electrochimica Acta.
Elsevier, 2008. https://doi.org/10.1016/j.electacta.2008.07.034.
ieee: R. Flückiger, S. A. Freunberger, D. Kramer, A. Wokaun, G. G. Scherer, and
F. N. Büchi, “Anisotropic, effective diffusivity of porous gas diffusion layer
materials for PEFC,” Electrochimica Acta, vol. 54, no. 2. Elsevier, pp.
551–559, 2008.
ista: Flückiger R, Freunberger SA, Kramer D, Wokaun A, Scherer GG, Büchi FN. 2008.
Anisotropic, effective diffusivity of porous gas diffusion layer materials for
PEFC. Electrochimica Acta. 54(2), 551–559.
mla: Flückiger, Reto, et al. “Anisotropic, Effective Diffusivity of Porous Gas Diffusion
Layer Materials for PEFC.” Electrochimica Acta, vol. 54, no. 2, Elsevier,
2008, pp. 551–59, doi:10.1016/j.electacta.2008.07.034.
short: R. Flückiger, S.A. Freunberger, D. Kramer, A. Wokaun, G.G. Scherer, F.N.
Büchi, Electrochimica Acta 54 (2008) 551–559.
date_created: 2020-01-15T12:21:36Z
date_published: 2008-12-30T00:00:00Z
date_updated: 2021-01-12T08:13:02Z
day: '30'
doi: 10.1016/j.electacta.2008.07.034
extern: '1'
intvolume: ' 54'
issue: '2'
language:
- iso: eng
month: '12'
oa_version: None
page: 551-559
publication: Electrochimica Acta
publication_identifier:
issn:
- 0013-4686
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Anisotropic, effective diffusivity of porous gas diffusion layer materials
for PEFC
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 54
year: '2008'
...
---
_id: '7321'
abstract:
- lang: eng
text: Cell interaction phenomena in polymer electrolyte fuel cell stacks that arise
from imbalance between adjacent cells are investigated in detail experimentally
and theoretically. A specialized two-cell stack with advanced localized diagnostics
was developed and used to analyze the mechanism and effect of cell-to-cell coupling
as a result of operationally relevant variations in reactant feed flow. Contributions
to overall and local voltage changes with respect to uniformly operated cells
are scrutinized. Unequal operation of the cells causes in-plane current in the
bipolar plate to redistribute current and result in inhomogeneous polarization.
Both increasing and decreasing polarization along the air-flow path reduces cell
power as compared to isopotential operation. A two-dimensional model based on
a commercial computational fluid dynamics code is used to back and extend the
experimental results to more general cases. Furthermore, the experimental setup
presented allowed for the first time to perform simultaneous localized electrochemical
impedance spectroscopy beyond the single-cell level. The mechanism of mutual cell
interaction on local and integral spectra is revealed. Results show that virtually
identical operation of the cells is essential to obtain meaningful integral spectra.
article_number: B704
article_processing_charge: No
article_type: original
author:
- first_name: Stefan Alexander
full_name: Freunberger, Stefan Alexander
id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
last_name: Freunberger
orcid: 0000-0003-2902-5319
- first_name: Ingo A.
full_name: Schneider, Ingo A.
last_name: Schneider
- first_name: Pang-Chieh
full_name: Sui, Pang-Chieh
last_name: Sui
- first_name: Alexander
full_name: Wokaun, Alexander
last_name: Wokaun
- first_name: Nedjib
full_name: Djilali, Nedjib
last_name: Djilali
- first_name: Felix N.
full_name: Büchi, Felix N.
last_name: Büchi
citation:
ama: Freunberger SA, Schneider IA, Sui P-C, Wokaun A, Djilali N, Büchi FN. Cell
interaction phenomena in polymer electrolyte fuel cell stacks. Journal of The
Electrochemical Society. 2008;155(7). doi:10.1149/1.2913095
apa: Freunberger, S. A., Schneider, I. A., Sui, P.-C., Wokaun, A., Djilali, N.,
& Büchi, F. N. (2008). Cell interaction phenomena in polymer electrolyte
fuel cell stacks. Journal of The Electrochemical Society. The Electrochemical
Society. https://doi.org/10.1149/1.2913095
chicago: Freunberger, Stefan Alexander, Ingo A. Schneider, Pang-Chieh Sui, Alexander
Wokaun, Nedjib Djilali, and Felix N. Büchi. “Cell Interaction Phenomena in Polymer
Electrolyte Fuel Cell Stacks.” Journal of The Electrochemical Society.
The Electrochemical Society, 2008. https://doi.org/10.1149/1.2913095.
ieee: S. A. Freunberger, I. A. Schneider, P.-C. Sui, A. Wokaun, N. Djilali, and
F. N. Büchi, “Cell interaction phenomena in polymer electrolyte fuel cell stacks,”
Journal of The Electrochemical Society, vol. 155, no. 7. The Electrochemical
Society, 2008.
ista: Freunberger SA, Schneider IA, Sui P-C, Wokaun A, Djilali N, Büchi FN. 2008.
Cell interaction phenomena in polymer electrolyte fuel cell stacks. Journal of
The Electrochemical Society. 155(7), B704.
mla: Freunberger, Stefan Alexander, et al. “Cell Interaction Phenomena in Polymer
Electrolyte Fuel Cell Stacks.” Journal of The Electrochemical Society,
vol. 155, no. 7, B704, The Electrochemical Society, 2008, doi:10.1149/1.2913095.
short: S.A. Freunberger, I.A. Schneider, P.-C. Sui, A. Wokaun, N. Djilali, F.N.
Büchi, Journal of The Electrochemical Society 155 (2008).
date_created: 2020-01-15T12:21:47Z
date_published: 2008-05-08T00:00:00Z
date_updated: 2021-01-12T08:13:03Z
day: '08'
doi: 10.1149/1.2913095
extern: '1'
intvolume: ' 155'
issue: '7'
language:
- iso: eng
month: '05'
oa_version: None
publication: Journal of The Electrochemical Society
publication_identifier:
issn:
- 0013-4651
publication_status: published
publisher: The Electrochemical Society
quality_controlled: '1'
status: public
title: Cell interaction phenomena in polymer electrolyte fuel cell stacks
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 155
year: '2008'
...
---
_id: '7322'
abstract:
- lang: eng
text: The gas diffusion layers (GDLs) of a membrane electrode assembly (MEA) serve
as link between flow field and porous electrode within a polymer electrolyte fuel
cell. Beside ensuring sufficient electrical and thermal contact between the whole
electrode area and the flow field, these typically 200–400 μm thick porous structures
enable the access of educts to the electrode area which would be occluded by the
flow field lands if the flow field is directly attached to the electrode. Hence,
the characterisation of properties pertaining to mass transport of educts and
products through these structures is indispensable whilst examining the contribution
of the GDLs to the overall electrochemical characteristics of a MEA. A fast and
cost effective method to measure the effective diffusivity of a GDL is presented.
Electrochemical impedance spectroscopy is applied to measure the effective ionic
conductivity of an electrolyte-soaked GDL. Taking advantage of the analogy between
Ficks and Ohms law, this provides a measure for the effective diffusivity. The
method is described in detail, including experimental as well as theoretical aspects,
and selected results, highlighting the anisotropy and dependence on the degree
of compression, are shown. Moreover, a two-dimensional model consisting of regularly
spaced ellipses is developed to represent the porous structure of the GDL, and
by using conformal maps, the agreement between this model and experiment with
respect to the sensitivity of the effective diffusivity towards compression is
shown.
article_processing_charge: No
article_type: original
author:
- first_name: Denis
full_name: Kramer, Denis
last_name: Kramer
- first_name: Stefan Alexander
full_name: Freunberger, Stefan Alexander
id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
last_name: Freunberger
orcid: 0000-0003-2902-5319
- first_name: Reto
full_name: Flückiger, Reto
last_name: Flückiger
- first_name: Ingo A.
full_name: Schneider, Ingo A.
last_name: Schneider
- first_name: Alexander
full_name: Wokaun, Alexander
last_name: Wokaun
- first_name: Felix N.
full_name: Büchi, Felix N.
last_name: Büchi
- first_name: Günther G.
full_name: Scherer, Günther G.
last_name: Scherer
citation:
ama: Kramer D, Freunberger SA, Flückiger R, et al. Electrochemical diffusimetry
of fuel cell gas diffusion layers. Journal of Electroanalytical Chemistry.
2008;612(1):63-77. doi:10.1016/j.jelechem.2007.09.014
apa: Kramer, D., Freunberger, S. A., Flückiger, R., Schneider, I. A., Wokaun, A.,
Büchi, F. N., & Scherer, G. G. (2008). Electrochemical diffusimetry of fuel
cell gas diffusion layers. Journal of Electroanalytical Chemistry. Elsevier.
https://doi.org/10.1016/j.jelechem.2007.09.014
chicago: Kramer, Denis, Stefan Alexander Freunberger, Reto Flückiger, Ingo A. Schneider,
Alexander Wokaun, Felix N. Büchi, and Günther G. Scherer. “Electrochemical Diffusimetry
of Fuel Cell Gas Diffusion Layers.” Journal of Electroanalytical Chemistry.
Elsevier, 2008. https://doi.org/10.1016/j.jelechem.2007.09.014.
ieee: D. Kramer et al., “Electrochemical diffusimetry of fuel cell gas diffusion
layers,” Journal of Electroanalytical Chemistry, vol. 612, no. 1. Elsevier,
pp. 63–77, 2008.
ista: Kramer D, Freunberger SA, Flückiger R, Schneider IA, Wokaun A, Büchi FN, Scherer
GG. 2008. Electrochemical diffusimetry of fuel cell gas diffusion layers. Journal
of Electroanalytical Chemistry. 612(1), 63–77.
mla: Kramer, Denis, et al. “Electrochemical Diffusimetry of Fuel Cell Gas Diffusion
Layers.” Journal of Electroanalytical Chemistry, vol. 612, no. 1, Elsevier,
2008, pp. 63–77, doi:10.1016/j.jelechem.2007.09.014.
short: D. Kramer, S.A. Freunberger, R. Flückiger, I.A. Schneider, A. Wokaun, F.N.
Büchi, G.G. Scherer, Journal of Electroanalytical Chemistry 612 (2008) 63–77.
date_created: 2020-01-15T12:21:57Z
date_published: 2008-01-01T00:00:00Z
date_updated: 2021-01-12T08:13:03Z
day: '01'
doi: 10.1016/j.jelechem.2007.09.014
extern: '1'
intvolume: ' 612'
issue: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 63-77
publication: Journal of Electroanalytical Chemistry
publication_identifier:
issn:
- 1572-6657
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Electrochemical diffusimetry of fuel cell gas diffusion layers
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 612
year: '2008'
...
---
_id: '7425'
abstract:
- lang: eng
text: The propagation of single cell performance losses to adjacent cells in a polymer
electrolyte fuel cell stack is studied by means of local current density measurements
in a two cell stack. In this stack, the working conditions of adjacent cells can
be controlled independently in order to deliberately change the performance of
one cell (inducing cell) and study the coupling effects to the adjacent cell (response
cell), while keeping the working conditions of the later one unchanged. The experiments
have shown that changes in the current density distribution caused by lowering
of the air stoichiometry in the inducing cell cause changes in the current density
distribution of the response cell in the order of 60% of the change of the inducing
cell, even when the air stoichiometry of the response cell is kept constant. The
losses in cell voltage of the inducing cell cause losses in cell voltage of the
response cell in a magnitude between 30 and 50%.
article_processing_charge: No
author:
- first_name: Marco
full_name: Santis, Marco
last_name: Santis
- first_name: Stefan Alexander
full_name: Freunberger, Stefan Alexander
id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
last_name: Freunberger
orcid: 0000-0003-2902-5319
- first_name: Matthias
full_name: Papra, Matthias
last_name: Papra
- first_name: Felix N.
full_name: Büchi, Felix N.
last_name: Büchi
citation:
ama: 'Santis M, Freunberger SA, Papra M, Büchi FN. Experimental investigation of
the propagation of local current density variations to adjacent cells in PEFC
stacks. In: 3rd International Conference on Fuel Cell Science, Engineering
and Technology. ASMEDC; 2008:763-765. doi:10.1115/fuelcell2005-74116'
apa: 'Santis, M., Freunberger, S. A., Papra, M., & Büchi, F. N. (2008). Experimental
investigation of the propagation of local current density variations to adjacent
cells in PEFC stacks. In 3rd International Conference on Fuel Cell Science,
Engineering and Technology (pp. 763–765). Ypsilanti, MI, United States: ASMEDC.
https://doi.org/10.1115/fuelcell2005-74116'
chicago: Santis, Marco, Stefan Alexander Freunberger, Matthias Papra, and Felix
N. Büchi. “Experimental Investigation of the Propagation of Local Current Density
Variations to Adjacent Cells in PEFC Stacks.” In 3rd International Conference
on Fuel Cell Science, Engineering and Technology, 763–65. ASMEDC, 2008. https://doi.org/10.1115/fuelcell2005-74116.
ieee: M. Santis, S. A. Freunberger, M. Papra, and F. N. Büchi, “Experimental investigation
of the propagation of local current density variations to adjacent cells in PEFC
stacks,” in 3rd International Conference on Fuel Cell Science, Engineering
and Technology, Ypsilanti, MI, United States, 2008, pp. 763–765.
ista: Santis M, Freunberger SA, Papra M, Büchi FN. 2008. Experimental investigation
of the propagation of local current density variations to adjacent cells in PEFC
stacks. 3rd International Conference on Fuel Cell Science, Engineering and Technology.
International conference on fuel cell science, engineering and technology, 763–765.
mla: Santis, Marco, et al. “Experimental Investigation of the Propagation of Local
Current Density Variations to Adjacent Cells in PEFC Stacks.” 3rd International
Conference on Fuel Cell Science, Engineering and Technology, ASMEDC, 2008,
pp. 763–65, doi:10.1115/fuelcell2005-74116.
short: M. Santis, S.A. Freunberger, M. Papra, F.N. Büchi, in:, 3rd International
Conference on Fuel Cell Science, Engineering and Technology, ASMEDC, 2008, pp.
763–765.
conference:
end_date: 2005-05-25
location: Ypsilanti, MI, United States
name: International conference on fuel cell science, engineering and technology
start_date: 2005-05-23
date_created: 2020-01-31T10:14:45Z
date_published: 2008-10-13T00:00:00Z
date_updated: 2021-01-12T08:13:33Z
day: '13'
doi: 10.1115/fuelcell2005-74116
extern: '1'
language:
- iso: eng
month: '10'
oa_version: None
page: 763-765
publication: 3rd International Conference on Fuel Cell Science, Engineering and Technology
publication_identifier:
isbn:
- '0791837645'
- '0791837572'
publication_status: published
publisher: ASMEDC
quality_controlled: '1'
status: public
title: Experimental investigation of the propagation of local current density variations
to adjacent cells in PEFC stacks
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2008'
...
---
_id: '753'
abstract:
- lang: eng
text: 'This paper addresses the following question: what is the minimum-sized synchronous
window needed to solve consensus in an otherwise asynchronous system? In answer
to this question, we present the first optimally-resilient algorithm ASAP that
solves consensus as soon as possible in an eventually synchronous system, i.e.,
a system that from some time GST onwards, delivers messages in a timely fashion.
ASAP guarantees that, in an execution with at most f failures, every process decides
no later than round GST + f + 2, which is optimal.'
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Dan-Adrian
full_name: Alistarh, Dan-Adrian
id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
last_name: Alistarh
orcid: 0000-0003-3650-940X
- first_name: Seth
full_name: Gilbert, Seth
last_name: Gilbert
- first_name: Rachid
full_name: Guerraoui, Rachid
last_name: Guerraoui
- first_name: Corentin
full_name: Travers, Corentin
last_name: Travers
citation:
ama: 'Alistarh D-A, Gilbert S, Guerraoui R, Travers C. How to solve consensus in
the smallest window of synchrony. In: Vol 5218 LNCS. Springer; 2008:32-46. doi:10.1007/978-3-540-87779-0_3'
apa: 'Alistarh, D.-A., Gilbert, S., Guerraoui, R., & Travers, C. (2008). How
to solve consensus in the smallest window of synchrony (Vol. 5218 LNCS, pp. 32–46).
Presented at the DISC: Distributed Computing, Springer. https://doi.org/10.1007/978-3-540-87779-0_3'
chicago: Alistarh, Dan-Adrian, Seth Gilbert, Rachid Guerraoui, and Corentin Travers.
“How to Solve Consensus in the Smallest Window of Synchrony,” 5218 LNCS:32–46.
Springer, 2008. https://doi.org/10.1007/978-3-540-87779-0_3.
ieee: 'D.-A. Alistarh, S. Gilbert, R. Guerraoui, and C. Travers, “How to solve consensus
in the smallest window of synchrony,” presented at the DISC: Distributed Computing,
2008, vol. 5218 LNCS, pp. 32–46.'
ista: 'Alistarh D-A, Gilbert S, Guerraoui R, Travers C. 2008. How to solve consensus
in the smallest window of synchrony. DISC: Distributed Computing, LNCS, vol. 5218
LNCS, 32–46.'
mla: Alistarh, Dan-Adrian, et al. How to Solve Consensus in the Smallest Window
of Synchrony. Vol. 5218 LNCS, Springer, 2008, pp. 32–46, doi:10.1007/978-3-540-87779-0_3.
short: D.-A. Alistarh, S. Gilbert, R. Guerraoui, C. Travers, in:, Springer, 2008,
pp. 32–46.
conference:
name: 'DISC: Distributed Computing'
date_created: 2018-12-11T11:48:19Z
date_published: 2008-01-01T00:00:00Z
date_updated: 2023-02-23T13:10:13Z
day: '01'
doi: 10.1007/978-3-540-87779-0_3
extern: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 32 - 46
publication_status: published
publisher: Springer
publist_id: '6904'
status: public
title: How to solve consensus in the smallest window of synchrony
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5218 LNCS
year: '2008'
...
---
OA_place: repository
OA_type: green
_id: '22049'
abstract:
- lang: eng
text: 'We consider the minimal mass m0 required for solutions to the mass-critical
nonlinear Schrödinger (NLS) equation iut + Δu = μ|u|^4/d u to blow up. If m0 is
finite, we show that there exists a minimal-mass solution blowing up (in the sense
of an infinite spacetime norm) in both time directions, whose orbit in is compact
after quotienting out by the symmetries of the equation. A similar result is obtained
for spherically symmetric solutions. Similar results were previously obtained
by Keraani, [Keraani S.: On the blow-up phenomenon of the critical nonlinear Schrödinger
equation. J. Funct. Anal. 235 (2006), 171–192], in dimensions 1, 2 and Begout
and Vargas, [Begout P., Vargas A.: Mass concentration phenomena for the L2-critical
nonlinear Schrödinger equation, preprint], in dimensions d ≥ 3 for the mass-critical
NLS and by Kenig and Merle, [Kenig C., Merle F.: Global well-posedness, scattering,
and blowup for the energy-critical, focusing, non-linear Schrödinger equation
in the radial case, preprint], in the energy-critical case. In a subsequent paper
we shall use this compactness result to establish global existence and scattering
in for the defocusing NLS in three and higher dimensions with spherically symmetric
data.'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Terence
full_name: Tao, Terence
last_name: Tao
- first_name: Monica
full_name: Visan, Monica
id: 056daca0-b8d1-11f0-964f-f91054abf8ca
last_name: Visan
- first_name: Xiaoyi
full_name: Zhang, Xiaoyi
last_name: Zhang
citation:
ama: Tao T, Vişan M, Zhang X. Minimal-mass blowup solutions of the mass-critical
NLS. Forum Mathematicum. 2008;20(5):881-919. doi:10.1515/forum.2008.042
apa: Tao, T., Vişan, M., & Zhang, X. (2008). Minimal-mass blowup solutions of
the mass-critical NLS. Forum Mathematicum. De Gruyter. https://doi.org/10.1515/forum.2008.042
chicago: Tao, Terence, Monica Vişan, and Xiaoyi Zhang. “Minimal-Mass Blowup Solutions
of the Mass-Critical NLS.” Forum Mathematicum. De Gruyter, 2008. https://doi.org/10.1515/forum.2008.042.
ieee: T. Tao, M. Vişan, and X. Zhang, “Minimal-mass blowup solutions of the mass-critical
NLS,” Forum Mathematicum, vol. 20, no. 5. De Gruyter, pp. 881–919, 2008.
ista: Tao T, Vişan M, Zhang X. 2008. Minimal-mass blowup solutions of the mass-critical
NLS. Forum Mathematicum. 20(5), 881–919.
mla: Tao, Terence, et al. “Minimal-Mass Blowup Solutions of the Mass-Critical NLS.”
Forum Mathematicum, vol. 20, no. 5, De Gruyter, 2008, pp. 881–919, doi:10.1515/forum.2008.042.
short: T. Tao, M. Vişan, X. Zhang, Forum Mathematicum 20 (2008) 881–919.
das_tickbox: '1'
date_created: 2026-06-19T07:53:12Z
date_published: 2008-11-03T00:00:00Z
date_updated: 2026-06-25T08:15:22Z
day: '03'
doi: 10.1515/forum.2008.042
extern: '1'
external_id:
arxiv:
- math/0609690
intvolume: ' 20'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.math/0609690
mathsc:
- 35Q55
month: '11'
oa: 1
oa_version: Preprint
page: 881-919
publication: Forum Mathematicum
publication_identifier:
eissn:
- 1435-5337
issn:
- 0933-7741
publication_status: published
publisher: De Gruyter
quality_controlled: '1'
scopus_import: '1'
status: public
title: Minimal-mass blowup solutions of the mass-critical NLS
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 20
year: '2008'
...
---
OA_place: repository
OA_type: green
_id: '22081'
abstract:
- lang: eng
text: We consider the Cauchy problem for a family of semilinear defocusing Schrödinger
equations with monomial nonlinearities in one space dimension. We establish global
well-posedness and scattering. Our analysis is based on a four-particle interaction
Morawetz estimate giving a priori $L_{t,x}^8$ spacetime control on solutions.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: J.
full_name: Colliander, J.
last_name: Colliander
- first_name: Justin
full_name: Holmer, Justin
last_name: Holmer
- first_name: Monica
full_name: Visan, Monica
id: 056daca0-b8d1-11f0-964f-f91054abf8ca
last_name: Visan
- first_name: Xiaoyi
full_name: Zhang, Xiaoyi
last_name: Zhang
citation:
ama: Colliander J, Holmer J, Vişan M, Zhang X. Global existence and scattering for
rough solutions to generalized nonlinear Schrödinger equations on $R$. Communications
on Pure and Applied Analysis. 2008;7(3):467-489. doi:10.3934/cpaa.2008.7.467
apa: Colliander, J., Holmer, J., Vişan, M., & Zhang, X. (2008). Global existence
and scattering for rough solutions to generalized nonlinear Schrödinger equations
on $R$. Communications on Pure and Applied Analysis. American Institute
of Mathematical Sciences. https://doi.org/10.3934/cpaa.2008.7.467
chicago: Colliander, J., Justin Holmer, Monica Vişan, and Xiaoyi Zhang. “Global
Existence and Scattering for Rough Solutions to Generalized Nonlinear Schrödinger
Equations on $R$.” Communications on Pure and Applied Analysis. American
Institute of Mathematical Sciences, 2008. https://doi.org/10.3934/cpaa.2008.7.467.
ieee: J. Colliander, J. Holmer, M. Vişan, and X. Zhang, “Global existence and scattering
for rough solutions to generalized nonlinear Schrödinger equations on $R$,” Communications
on Pure and Applied Analysis, vol. 7, no. 3. American Institute of Mathematical
Sciences, pp. 467–489, 2008.
ista: Colliander J, Holmer J, Vişan M, Zhang X. 2008. Global existence and scattering
for rough solutions to generalized nonlinear Schrödinger equations on $R$. Communications
on Pure and Applied Analysis. 7(3), 467–489.
mla: Colliander, J., et al. “Global Existence and Scattering for Rough Solutions
to Generalized Nonlinear Schrödinger Equations on $R$.” Communications on Pure
and Applied Analysis, vol. 7, no. 3, American Institute of Mathematical Sciences,
2008, pp. 467–89, doi:10.3934/cpaa.2008.7.467.
short: J. Colliander, J. Holmer, M. Vişan, X. Zhang, Communications on Pure and
Applied Analysis 7 (2008) 467–489.
das_tickbox: '1'
date_created: 2026-06-19T08:27:11Z
date_published: 2008-03-01T00:00:00Z
date_updated: 2026-07-01T07:05:55Z
day: '01'
doi: 10.3934/cpaa.2008.7.467
extern: '1'
external_id:
arxiv:
- math/0612452
intvolume: ' 7'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.math/0612452
mathsc:
- 35Q55
month: '03'
oa: 1
oa_version: Preprint
page: 467-489
publication: Communications on Pure and Applied Analysis
publication_identifier:
eissn:
- 1553-5258
issn:
- 1534-0392
publication_status: published
publisher: American Institute of Mathematical Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Global existence and scattering for rough solutions to generalized nonlinear
Schrödinger equations on $R$
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2008'
...
---
OA_place: repository
OA_type: green
_id: '22082'
abstract:
- lang: eng
text: "We establish global well-posedness and scattering for solutions to the mass-critical
nonlinear Schrödinger equation (mathematical formular) for large spherically
symmetric L2/x(R^d) initial data in dimensions d >= 3.\r\nIn the focusing case
we require that the mass is strictly less than that of the ground state. As a
consequence, we obtain that in the focusing case, any spherically symmetric blowup
solution must concentrate at least the mass of the ground state at the blowup
time."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Rowan
full_name: Killip, Rowan
last_name: Killip
- first_name: Monica
full_name: Visan, Monica
id: 056daca0-b8d1-11f0-964f-f91054abf8ca
last_name: Visan
- first_name: Xiaoyi
full_name: Zhang, Xiaoyi
last_name: Zhang
citation:
ama: Killip R, Vişan M, Zhang X. The mass-critical nonlinear Schrödinger equation
with radial data in dimensions three and higher. Analysis & PDE. 2008;1(2):229-266.
doi:10.2140/apde.2008.1.229
apa: Killip, R., Vişan, M., & Zhang, X. (2008). The mass-critical nonlinear
Schrödinger equation with radial data in dimensions three and higher. Analysis
& PDE. Mathematical Sciences Publishers. https://doi.org/10.2140/apde.2008.1.229
chicago: Killip, Rowan, Monica Vişan, and Xiaoyi Zhang. “The Mass-Critical Nonlinear
Schrödinger Equation with Radial Data in Dimensions Three and Higher.” Analysis
& PDE. Mathematical Sciences Publishers, 2008. https://doi.org/10.2140/apde.2008.1.229.
ieee: R. Killip, M. Vişan, and X. Zhang, “The mass-critical nonlinear Schrödinger
equation with radial data in dimensions three and higher,” Analysis & PDE,
vol. 1, no. 2. Mathematical Sciences Publishers, pp. 229–266, 2008.
ista: Killip R, Vişan M, Zhang X. 2008. The mass-critical nonlinear Schrödinger
equation with radial data in dimensions three and higher. Analysis & PDE.
1(2), 229–266.
mla: Killip, Rowan, et al. “The Mass-Critical Nonlinear Schrödinger Equation with
Radial Data in Dimensions Three and Higher.” Analysis & PDE, vol. 1,
no. 2, Mathematical Sciences Publishers, 2008, pp. 229–66, doi:10.2140/apde.2008.1.229.
short: R. Killip, M. Vişan, X. Zhang, Analysis & PDE 1 (2008) 229–266.
das_tickbox: '1'
date_created: 2026-06-19T08:27:33Z
date_published: 2008-06-01T00:00:00Z
date_updated: 2026-07-01T07:15:15Z
day: '01'
doi: 10.2140/apde.2008.1.229
extern: '1'
external_id:
arxiv:
- '0708.0849'
intvolume: ' 1'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.0708.0849
month: '06'
oa: 1
oa_version: Preprint
page: 229-266
publication: Analysis & PDE
publication_identifier:
eissn:
- 1948-206X
issn:
- 2157-5045
publication_status: published
publisher: Mathematical Sciences Publishers
quality_controlled: '1'
scopus_import: '1'
status: public
title: The mass-critical nonlinear Schrödinger equation with radial data in dimensions
three and higher
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1
year: '2008'
...
---
_id: '11115'
abstract:
- lang: eng
text: The formation of the nuclear envelope (NE) around chromatin is a major membrane-remodelling
event that occurs during cell division of metazoa. It is unclear whether the nuclear
membrane reforms by the fusion of NE fragments or if it re-emerges from an intact
tubular network of the endoplasmic reticulum (ER). Here, we show that NE formation
and expansion requires a tubular ER network and occurs efficiently in the presence
of the membrane fusion inhibitor GTPγS. Chromatin recruitment of membranes, which
is initiated by tubule-end binding, followed by the formation, expansion and sealing
of flat membrane sheets, is mediated by DNA-binding proteins residing in the ER.
Thus, chromatin plays an active role in reshaping of the ER during NE formation.
article_processing_charge: No
article_type: original
author:
- first_name: Daniel J.
full_name: Anderson, Daniel J.
last_name: Anderson
- first_name: Martin W
full_name: HETZER, Martin W
id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
last_name: HETZER
orcid: 0000-0002-2111-992X
citation:
ama: Anderson DJ, Hetzer M. Nuclear envelope formation by chromatin-mediated reorganization
of the endoplasmic reticulum. Nature Cell Biology. 2007;9(10):1160-1166.
doi:10.1038/ncb1636
apa: Anderson, D. J., & Hetzer, M. (2007). Nuclear envelope formation by chromatin-mediated
reorganization of the endoplasmic reticulum. Nature Cell Biology. Springer
Nature. https://doi.org/10.1038/ncb1636
chicago: Anderson, Daniel J., and Martin Hetzer. “Nuclear Envelope Formation by
Chromatin-Mediated Reorganization of the Endoplasmic Reticulum.” Nature Cell
Biology. Springer Nature, 2007. https://doi.org/10.1038/ncb1636.
ieee: D. J. Anderson and M. Hetzer, “Nuclear envelope formation by chromatin-mediated
reorganization of the endoplasmic reticulum,” Nature Cell Biology, vol.
9, no. 10. Springer Nature, pp. 1160–1166, 2007.
ista: Anderson DJ, Hetzer M. 2007. Nuclear envelope formation by chromatin-mediated
reorganization of the endoplasmic reticulum. Nature Cell Biology. 9(10), 1160–1166.
mla: Anderson, Daniel J., and Martin Hetzer. “Nuclear Envelope Formation by Chromatin-Mediated
Reorganization of the Endoplasmic Reticulum.” Nature Cell Biology, vol.
9, no. 10, Springer Nature, 2007, pp. 1160–66, doi:10.1038/ncb1636.
short: D.J. Anderson, M. Hetzer, Nature Cell Biology 9 (2007) 1160–1166.
date_created: 2022-04-07T07:56:04Z
date_published: 2007-09-09T00:00:00Z
date_updated: 2024-10-14T11:30:08Z
day: '09'
doi: 10.1038/ncb1636
extern: '1'
external_id:
pmid:
- '17828249'
intvolume: ' 9'
issue: '10'
keyword:
- Cell Biology
language:
- iso: eng
month: '09'
oa_version: None
page: 1160-1166
pmid: 1
publication: Nature Cell Biology
publication_identifier:
eissn:
- 1476-4679
issn:
- 1465-7392
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Nuclear envelope formation by chromatin-mediated reorganization of the endoplasmic
reticulum
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2007'
...