Please note that LibreCat no longer supports Internet Explorer versions 8 or 9 (or earlier).

We recommend upgrading to the latest Internet Explorer, Google Chrome, or Firefox.

Athina Diakogianni

Stepan Ovchinnikov

Calin Guet

Bryan Wu

Ekaterina Krasnopeeva

Roderich Römhild

Puzhen Xia

Nathalie Gruber

Tobias Bergmiller

Tiago Paixao

Maros Pleska

Stephanie Kainrath

Tatjana Petrov

Maria Mateescu

Claudia Igler

Moritz Lang

Remy Chait

Anna Nagy-Staron

Isabella Tomanek

Nela Nikolic

Rok Grah

Nikola Zarevski

Kirti Jain

Mato Lagator



119 Publications

2023 | Journal Article | IST-REx-ID: 12478 | OA
Monitoring lineages of growing and dividing bacteria reveals an inducible memory of mar operon expression
C.C. Guet, L. Bruneaux, P. Oikonomou, M. Aldana, P. Cluzel, Frontiers in Microbiology 14 (2023).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
2022 | Journal Article | IST-REx-ID: 10939 | OA
Parameter inference for stochastic biochemical models from perturbation experiments parallelised at the single cell level
A. Davidović, R.P. Chait, G. Batt, J. Ruess, PLoS Computational Biology 18 (2022).
[Published Version] View | Files available | DOI
 
2022 | Journal Article | IST-REx-ID: 11713 | OA
Quantifying heterologous gene expression during ectopic MazF production in Escherichia coli
N. Nikolic, M. Sauert, T.G. Albanese, I. Moll, BMC Research Notes 15 (2022).
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
2022 | Journal Article | IST-REx-ID: 10736 | OA
Predicting bacterial promoter function and evolution from random sequences
M. Lagator, S. Sarikas, M. Steinrueck, D. Toledo-Aparicio, J.P. Bollback, C.C. Guet, G. Tkačik, ELife 11 (2022).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
2022 | Journal Article | IST-REx-ID: 10812
The physiology and genetics of bacterial responses to antibiotic combinations
R. Römhild, M.T. Bollenbach, D.I. Andersson, Nature Reviews Microbiology 20 (2022) 478–490.
View | DOI | WoS | PubMed | Europe PMC
 
2022 | Journal Article | IST-REx-ID: 11339 | OA
Nutrient and salt depletion synergistically boosts glucose metabolism in individual Escherichia coli cells
G. Glover, M. Voliotis, U. Łapińska, B.M. Invergo, D. Soanes, P. O’Neill, K. Moore, N. Nikolic, P. Petrov, D.S. Milner, S. Roy, K. Heesom, T.A. Richards, K. Tsaneva-Atanasova, S. Pagliara, Communications Biology 5 (2022).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
2022 | Journal Article | IST-REx-ID: 11843 | OA
Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14
K. Tomasek, A.F. Leithner, I. Glatzová, M.S. Lukesch, C.C. Guet, M.K. Sixt, ELife 11 (2022).
[Published Version] View | Files available | DOI | WoS
 
2022 | Journal Article | IST-REx-ID: 12333 | OA
Adaptation dynamics between copynumber and point mutations
I. Tomanek, C.C. Guet, ELife 11 (2022).
[Published Version] View | Files available | DOI | WoS
 
2022 | Research Data Reference | IST-REx-ID: 12339 | OA
Flow cytometry YFP and CFP data and deep sequencing data of populations evolving in galactose
I. Tomanek, C.C. Guet, (2022).
[Published Version] View | Files available | DOI | Download Published Version (ext.)
 
2021 | Journal Article | IST-REx-ID: 9046 | OA
Mechanisms and therapeutic potential of collateral sensitivity to antibiotics
R. Römhild, D.I. Andersson, PLoS Pathogens 17 (2021).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
2021 | Journal Article | IST-REx-ID: 9647 | OA
Long lived transients in gene regulation
T. Petrov, C. Igler, A. Sezgin, T.A. Henzinger, C.C. Guet, Theoretical Computer Science 893 (2021) 1–16.
[Published Version] View | Files available | DOI | WoS
 
2021 | Journal Article | IST-REx-ID: 9822 | OA
Sequential and switchable patterning for studying cellular processes under spatiotemporal control
T. Zisis, J. Schwarz, M. Balles, M. Kretschmer, M. Nemethova, R.P. Chait, R. Hauschild, J. Lange, C.C. Guet, M.K. Sixt, S. Zahler, ACS Applied Materials and Interfaces 13 (2021) 35545–35560.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
2021 | Journal Article | IST-REx-ID: 9746 | OA
High potency of sequential therapy with only beta-lactam antibiotics
A. Batra, R. Römhild, E. Rousseau, S. Franzenburg, S. Niemann, H. Schulenburg, ELife 10 (2021).
[Published Version] View | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 
2021 | Journal Article | IST-REx-ID: 10363 | OA
Rational engineering of an erythropoietin fusion protein to treat hypoxia
J. Lee, A. Vernet, N. Gruber, K.M. Kready, D.R. Burrill, J.C. Way, P.A. Silver, Protein Engineering, Design and Selection 34 (2021).
[Published Version] View | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 
2021 | Journal Article | IST-REx-ID: 9283 | OA
Local genetic context shapes the function of a gene regulatory network
A.A. Nagy-Staron, K. Tomasek, C. Caruso Carter, E. Sonnleitner, B. Kavcic, T. Paixão, C.C. Guet, ELife 10 (2021).
[Published Version] View | Files available | DOI | WoS
 
2021 | Journal Article | IST-REx-ID: 15270 | OA
Active efflux leads to heterogeneous dissipation of proton motive force by protonophores in bacteria
D. Le, E. Krasnopeeva, F. Sinjab, T. Pilizota, M. Kim, MBio 12 (2021).
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
2021 | Thesis | IST-REx-ID: 10307 | OA
Pathogenic Escherichia coli hijack the host immune response
K. Tomasek, Pathogenic Escherichia Coli Hijack the Host Immune Response, Institute of Science and Technology Austria, 2021.
[Published Version] View | Files available | DOI
 
2021 | Preprint | IST-REx-ID: 10316 | OA
Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14
K. Tomasek, A.F. Leithner, I. Glatzová, M.S. Lukesch, C.C. Guet, M.K. Sixt, BioRxiv (n.d.).
[Preprint] View | Files available | DOI | Download Preprint (ext.)
 
2020 | Book Chapter | IST-REx-ID: 8173
Design and application of light-regulated receptor tyrosine kinases
S. Kainrath, H.L. Janovjak, in:, D. Niopek (Ed.), Photoswitching Proteins, Springer Nature, 2020, pp. 233–246.
View | DOI
 
2020 | Thesis | IST-REx-ID: 8155 | OA
Gene regulation across scales – how biophysical constraints shape evolution
R. Grah, Gene Regulation across Scales – How Biophysical Constraints Shape Evolution, Institute of Science and Technology Austria, 2020.
[Published Version] View | Files available | DOI
 
2020 | Preprint | IST-REx-ID: 7675 | OA
Normative models of enhancer function
R. Grah, B. Zoller, G. Tkačik, BioRxiv (2020).
[Preprint] View | Files available | DOI | Download Preprint (ext.)
 
2020 | Journal Article | IST-REx-ID: 7569 | OA
The relation between crosstalk and gene regulation form revisited
R. Grah, T. Friedlander, PLOS Computational Biology 16 (2020).
[Published Version] View | Files available | DOI | WoS
 
2020 | Thesis | IST-REx-ID: 7680 | OA
Synthetic tools for optogenetic and chemogenetic inhibition of cellular signals
S. Kainrath, Synthetic Tools for Optogenetic and Chemogenetic Inhibition of Cellular Signals, Institute of Science and Technology Austria, 2020.
View | Files available | DOI
 
2020 | Journal Article | IST-REx-ID: 7652 | OA
Gene amplification as a form of population-level gene expression regulation
I. Tomanek, R. Grah, M. Lagator, A.M.C. Andersson, J.P. Bollback, G. Tkačik, C.C. Guet, Nature Ecology & Evolution 4 (2020) 612–625.
[Submitted Version] View | Files available | DOI | WoS
 
2020 | Thesis | IST-REx-ID: 8653 | OA
The evolution of gene expression by copy number and point mutations
I. Tomanek, The Evolution of Gene Expression by Copy Number and Point Mutations, Institute of Science and Technology Austria, 2020.
[Published Version] View | Files available | DOI
 
2019 | Journal Article | IST-REx-ID: 6465 | OA
A modular degron library for synthetic circuits in mammalian cells
H. Chassin, M. Müller, M. Tigges, L. Scheller, M. Lang, M. Fussenegger, Nature Communications 10 (2019).
[Published Version] View | Files available | DOI | WoS
 
2019 | Journal Article | IST-REx-ID: 6717 | OA
Commentary: A host-produced quorum-sensing autoinducer controls a phage lysis-lysogeny decision
C. Igler, S.T. Abedon, Frontiers in Microbiology 10 (2019).
[Published Version] View | Files available | DOI | WoS
 
2019 | Journal Article | IST-REx-ID: 6784 | OA
Molecular noise of innate immunity shapes bacteria-phage ecologies
J. Ruess, M. Pleska, C.C. Guet, G. Tkačik, PLoS Computational Biology 15 (2019).
[Published Version] View | Files available | DOI | WoS
 
2019 | Research Data Reference | IST-REx-ID: 9786
Supporting text and results
J. Ruess, M. Pleska, C.C. Guet, G. Tkačik, (2019).
[Published Version] View | Files available | DOI
 
2019 | Conference Paper | IST-REx-ID: 7147
Transient memory in gene regulation
C.C. Guet, T.A. Henzinger, C. Igler, T. Petrov, A. Sezgin, in:, 17th International Conference on Computational Methods in Systems Biology, Springer Nature, 2019, pp. 155–187.
View | DOI | WoS
 
2019 | Journal Article | IST-REx-ID: 138 | OA
Autoregulation of bacterial gene expression: lessons from the MazEF toxin–antitoxin system
N. Nikolic, Current Genetics 65 (2019) 133–138.
[Published Version] View | Files available | DOI | WoS
 
2019 | Journal Article | IST-REx-ID: 196 | OA
Harmonic dynamics of the Abelian sandpile
M. Lang, M. Shkolnikov, Proceedings of the National Academy of Sciences 116 (2019) 2821–2830.
[Published Version] View | Files available | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC | arXiv
 
2019 | Thesis | IST-REx-ID: 6371 | OA
On the nature of gene regulatory design - The biophysics of transcription factor binding shapes gene regulation
C. Igler, On the Nature of Gene Regulatory Design - The Biophysics of Transcription Factor Binding Shapes Gene Regulation, Institute of Science and Technology Austria, 2019.
[Published Version] View | Files available | DOI
 
2018 | Journal Article | IST-REx-ID: 305
Fabrication and operation of microfluidic hanging drop networks
P. Misun, A. Birchler, M. Lang, A. Hierlemann, O. Frey, Methods in Molecular Biology 1771 (2018) 183–202.
View | DOI
 
2018 | Journal Article | IST-REx-ID: 723 | OA
How to escape local optima in black box optimisation when non elitism outperforms elitism
P. Oliveto, T. Paixao, J. Pérez Heredia, D. Sudholt, B. Trubenova, Algorithmica 80 (2018) 1604–1633.
[Published Version] View | Files available | DOI | WoS
 
2018 | Journal Article | IST-REx-ID: 503
Lack of cations in flow cytometry buffers affect fluorescence signals by reducing membrane stability and viability of Escherichia coli strains
K. Tomasek, T. Bergmiller, C.C. Guet, Journal of Biotechnology 268 (2018) 40–52.
View | DOI | WoS
 
2018 | Journal Article | IST-REx-ID: 82 | OA
Leaky resistance and the conditions for the existence of lytic bacteriophage
W. Chaudhry, M. Pleska, N. Shah, H. Weiss, I. Mccall, J. Meyer, A. Gupta, C.C. Guet, B. Levin, PLoS Biology 16 (2018).
[Published Version] View | Files available | DOI | WoS
 
2018 | Research Data Reference | IST-REx-ID: 9810
Numerical data used in figures
W. Chaudhry, M. Pleska, N. Shah, H. Weiss, I. Mccall, J. Meyer, A. Gupta, C.C. Guet, B. Levin, (2018).
[Published Version] View | Files available | DOI
 
2018 | Journal Article | IST-REx-ID: 457
Phage-host population dynamics promotes prophage acquisition in bacteria with innate immunity
M. Pleska, M. Lang, D. Refardt, B. Levin, C.C. Guet, Nature Ecology and Evolution 2 (2018) 359–366.
View | Files available | DOI | WoS
 
2018 | Journal Article | IST-REx-ID: 5984 | OA
Optical functionalization of human class A orphan G-protein-coupled receptors
M. Morri, I. Sanchez-Romero, A.-M. Tichy, S. Kainrath, E.J. Gerrard, P. Hirschfeld, J. Schwarz, H.L. Janovjak, Nature Communications 9 (2018).
[Published Version] View | Files available | DOI | WoS
 
2018 | Journal Article | IST-REx-ID: 19 | OA
Nonoptimal gene expression creates latent potential for antibiotic resistance
A. Palmer, R.P. Chait, R. Kishony, Molecular Biology and Evolution 35 (2018) 2669–2684.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | WoS | PubMed | Europe PMC
 
2018 | Journal Article | IST-REx-ID: 438 | OA
Autoregulation of mazEF expression underlies growth heterogeneity in bacterial populations
N. Nikolic, T. Bergmiller, A. Vandervelde, T. Albanese, L. Gelens, I. Moll, Nucleic Acids Research 46 (2018) 2918–2931.
[Published Version] View | Files available | DOI | WoS
 
2018 | Journal Article | IST-REx-ID: 161 | OA
Statistical mechanics for metabolic networks during steady state growth
D. De Martino, A.A. Mc, T. Bergmiller, C.C. Guet, G. Tkačik, Nature Communications 9 (2018).
[Published Version] View | Files available | DOI | WoS
 
2018 | Thesis | IST-REx-ID: 26 | OA
The influence of sequence context on the evolution of bacterial gene expression
M. Steinrück, The Influence of Sequence Context on the Evolution of Bacterial Gene Expression, Institute of Science and Technology Austria, 2018.
[Published Version] View | Files available | DOI
 
2018 | Journal Article | IST-REx-ID: 67 | OA
Evolutionary potential of transcription factors for gene regulatory rewiring
C. Igler, M. Lagator, G. Tkačik, J.P. Bollback, C.C. Guet, Nature Ecology and Evolution 2 (2018) 1633–1643.
[Submitted Version] View | Files available | DOI | WoS
 
2017 | Journal Article | IST-REx-ID: 538 | OA
Grünlicht-induzierte Rezeptorinaktivierung durch Cobalamin-bindende Domänen
S. Kainrath, M. Stadler, E. Gschaider-Reichhart, M. Distel, H.L. Janovjak, Angewandte Chemie 129 (2017) 4679–4682.
[Published Version] View | Files available | DOI
 
2017 | Journal Article | IST-REx-ID: 570 | OA
Regulatory network structure determines patterns of intermolecular epistasis
M. Lagator, S. Sarikas, H. Acar, J.P. Bollback, C.C. Guet, ELife 6 (2017).
[Published Version] View | Files available | DOI
 
2017 | Journal Article | IST-REx-ID: 613 | OA
Shaping bacterial population behavior through computer interfaced control of individual cells
R.P. Chait, J. Ruess, T. Bergmiller, G. Tkačik, C.C. Guet, Nature Communications 8 (2017).
[Published Version] View | Files available | DOI
 
2017 | Journal Article | IST-REx-ID: 624 | OA
MazF activation promotes translational heterogeneity of the grcA mRNA in Escherichia coli populations
N. Nikolic, Z. Didara, I. Moll, PeerJ 2017 (2017).
[Published Version] View | Files available | DOI
 
2017 | Journal Article | IST-REx-ID: 655 | OA
Bacterial flagella grow through an injection diffusion mechanism
T. Renault, A. Abraham, T. Bergmiller, G. Paradis, S. Rainville, E. Charpentier, C.C. Guet, Y. Tu, K. Namba, J. Keener, T. Minamino, M. Erhardt, ELife 6 (2017).
[Published Version] View | Files available | DOI
 
2017 | Journal Article | IST-REx-ID: 541 | OA
Cell-to-cell variation and specialization in sugar metabolism in clonal bacterial populations
N. Nikolic, F. Schreiber, A. Dal Co, D. Kiviet, T. Bergmiller, S. Littmann, M. Kuypers, M. Ackermann, PLoS Genetics 13 (2017).
[Published Version] View | Files available | DOI
 
2017 | Research Data Reference | IST-REx-ID: 9847 | OA
Supplementary materials and methods; Full data set from effects of mutations in phage restriction sites during escape from restriction–modification
M. Pleska, C.C. Guet, (2017).
[Published Version] View | Files available | DOI | Download Published Version (ext.)
 
2017 | Research Data Reference | IST-REx-ID: 9845
Mathematical model
N. Nikolic, F. Schreiber, A. Dal Co, D. Kiviet, T. Bergmiller, S. Littmann, M. Kuypers, M. Ackermann, (2017).
View | Files available | DOI
 
2017 | Research Data Reference | IST-REx-ID: 9849
Modelling and simulation details
M. Lukacisinova, S. Novak, T. Paixao, (2017).
[Published Version] View | Files available | DOI
 
2017 | Research Data Reference | IST-REx-ID: 9850
Extensions of the model
M. Lukacisinova, S. Novak, T. Paixao, (2017).
[Published Version] View | Files available | DOI
 
2017 | Research Data Reference | IST-REx-ID: 9846
Supplementary methods
N. Nikolic, F. Schreiber, A. Dal Co, D. Kiviet, T. Bergmiller, S. Littmann, M. Kuypers, M. Ackermann, (2017).
[Published Version] View | Files available | DOI
 
2017 | Research Data Reference | IST-REx-ID: 9851
Heuristic prediction for multiple stresses
M. Lukacisinova, S. Novak, T. Paixao, (2017).
[Published Version] View | Files available | DOI
 
2017 | Research Data Reference | IST-REx-ID: 9852
Resistance frequencies for different combination strategies
M. Lukacisinova, S. Novak, T. Paixao, (2017).
[Published Version] View | Files available | DOI
 
2017 | Research Data Reference | IST-REx-ID: 9844
Source data for figures and tables
N. Nikolic, F. Schreiber, A. Dal Co, D. Kiviet, T. Bergmiller, S. Littmann, M. Kuypers, M. Ackermann, (2017).
[Published Version] View | Files available | DOI
 
2017 | Journal Article | IST-REx-ID: 561 | OA
Effects of mutations in phage restriction sites during escape from restriction–modification
M. Pleska, C.C. Guet, Biology Letters 13 (2017).
[Published Version] View | Files available | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
2017 | Thesis | IST-REx-ID: 202 | OA
Biology of restriction-modification systems at the single-cell and population level
M. Pleska, Biology of Restriction-Modification Systems at the Single-Cell and Population Level, Institute of Science and Technology Austria, 2017.
[Published Version] View | Files available | DOI
 
2017 | Journal Article | IST-REx-ID: 1351 | OA
Model checking the evolution of gene regulatory networks
M. Giacobbe, C.C. Guet, A. Gupta, T.A. Henzinger, T. Paixao, T. Petrov, Acta Informatica 54 (2017) 765–787.
[Published Version] View | Files available | DOI | WoS
 
2017 | Journal Article | IST-REx-ID: 1336 | OA
Towards a runtime comparison of natural and artificial evolution
T. Paixao, J. Pérez Heredia, D. Sudholt, B. Trubenova, Algorithmica 78 (2017) 681–713.
[Published Version] View | Files available | DOI | WoS
 
2017 | Journal Article | IST-REx-ID: 1084
Insulation and wiring specificity of BceR like response regulators and their target promoters in Bacillus subtilis
C. Fang, A.A. Nagy-Staron, M. Grafe, R. Heermann, K. Jung, S. Gebhard, T. Mascher, Molecular Microbiology 104 (2017) 16–31.
View | DOI | WoS
 
2017 | Journal Article | IST-REx-ID: 954 | OA
On the mechanistic nature of epistasis in a canonical cis-regulatory element
M. Lagator, T. Paixao, N.H. Barton, J.P. Bollback, C.C. Guet, ELife 6 (2017).
[Published Version] View | Files available | DOI | WoS
 
2017 | Journal Article | IST-REx-ID: 1007 | OA
Zeros of nonlinear systems with input invariances
M. Lang, E. Sontag, Automatica 81C (2017) 46–55.
[Published Version] View | Files available | DOI | WoS
 
2017 | Journal Article | IST-REx-ID: 665
Biased partitioning of the multidrug efflux pump AcrAB TolC underlies long lived phenotypic heterogeneity
T. Bergmiller, A.M. Andersson, K. Tomasek, E. Balleza, D. Kiviet, R. Hauschild, G. Tkačik, C.C. Guet, Science 356 (2017) 311–315.
View | Files available | DOI
 
2017 | Journal Article | IST-REx-ID: 1028 | OA
Green-light-induced inactivation of receptor signaling using cobalamin-binding domains
S. Kainrath, M. Stadler, E. Gschaider-Reichhart, M. Distel, H.L. Janovjak, Angewandte Chemie - International Edition 56 (2017) 4608–4611.
[Published Version] View | Files available | DOI | WoS
 
2017 | Journal Article | IST-REx-ID: 704 | OA
Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection
M. Steinrück, C.C. Guet, ELife 6 (2017).
[Published Version] View | Files available | DOI
 
2017 | Journal Article | IST-REx-ID: 696 | OA
Stress induced mutagenesis: Stress diversity facilitates the persistence of mutator genes
M. Lukacisinova, S. Novak, T. Paixao, PLoS Computational Biology 13 (2017).
[Published Version] View | Files available | DOI
 
2017 | Journal Article | IST-REx-ID: 735
An effective feedback loop between cell-cell contact duration and morphogen signaling determines cell fate
V. Barone, M. Lang, G. Krens, S. Pradhan, S. Shamipour, K. Sako, M.K. Sikora, C.C. Guet, C.-P.J. Heisenberg, Developmental Cell 43 (2017) 198–211.
View | Files available | DOI | WoS
 
2016 | Journal Article | IST-REx-ID: 1008
An orthogonal permease–inducer–repressor feedback loop shows bistability
R. Gnügge, L. Dharmarajan, M. Lang, J. Stelling, ACS Synthetic Biology 5 (2016) 1098–1107.
View | DOI
 
2016 | Journal Article | IST-REx-ID: 1170
Modular parameter identification of biomolecular networks
M. Lang, J. Stelling, SIAM Journal on Scientific Computing 38 (2016) B988–B1008.
[Submitted Version] View | Files available | DOI
 
2016 | Conference Paper | IST-REx-ID: 1220 | OA
Fuselage boundary layer ingestion propulsion applied to a thin haul commuter aircraft for optimal efficiency
G. Mikić, A. Stoll, J. Bevirt, R. Grah, M. Moore, in:, AIAA, 2016, pp. 1–19.
[Preprint] View | DOI | Download Preprint (ext.)
 
2016 | Journal Article | IST-REx-ID: 1290 | OA
Compounds that select against the tetracycline-resistance efflux pump
L. Stone, M. Baym, T. Lieberman, R.P. Chait, J. Clardy, R. Kishony, Nature Chemical Biology 12 (2016) 902–904.
[Preprint] View | DOI | Download Preprint (ext.)
 
2016 | Conference Paper | IST-REx-ID: 1320
Scale-invariant systems realize nonlinear differential operators
M. Lang, E. Sontag, in:, IEEE, 2016.
[Preprint] View | Files available | DOI
 
2016 | Journal Article | IST-REx-ID: 1332 | OA
Pervasive selection for and against antibiotic resistance in inhomogeneous multistress environments
R.P. Chait, A. Palmer, I. Yelin, R. Kishony, Nature Communications 7 (2016).
[Published Version] View | Files available | DOI
 
2016 | Journal Article | IST-REx-ID: 1342 | OA
Spatiotemporal microbial evolution on antibiotic landscapes
M. Baym, T. Lieberman, E. Kelsic, R.P. Chait, R. Gross, I. Yelin, R. Kishony, Science 353 (2016) 1147–1151.
[Preprint] View | DOI | Download Preprint (ext.)
 
2016 | Conference Paper | IST-REx-ID: 1349 | OA
When non-elitism outperforms elitism for crossing fitness valleys
P. Oliveto, T. Paixao, J. Heredia, D. Sudholt, B. Trubenova, in:, Proceedings of the Genetic and Evolutionary Computation Conference 2016 , ACM, 2016, pp. 1163–1170.
[Published Version] View | Files available | DOI
 
2016 | Journal Article | IST-REx-ID: 1359 | OA
The effect of gene interactions on the long-term response to selection
T. Paixao, N.H. Barton, PNAS 113 (2016) 4422–4427.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
2016 | Journal Article | IST-REx-ID: 1427 | OA
Epistatic interactions in the arabinose cis-regulatory element
M. Lagator, C. Igler, A. Moreno, C.C. Guet, J.P. Bollback, Molecular Biology and Evolution 33 (2016) 761–769.
[Published Version] View | Files available | DOI
 
2016 | Conference Paper | IST-REx-ID: 1524 | OA
Efficient reduction of kappa models by static inspection of the rule-set
A. Beica, C.C. Guet, T. Petrov, in:, Springer, 2016, pp. 173–191.
[Preprint] View | DOI | Download Preprint (ext.)
 
2016 | Journal Article | IST-REx-ID: 1250 | OA
Genetic manipulation of glycogen allocation affects replicative lifespan in E coli
A. Boehm, M. Arnoldini, T. Bergmiller, T. Röösli, C. Bigosch, M. Ackermann, PLoS Genetics 12 (2016).
[Published Version] View | Files available | DOI
 
2016 | Research Data Reference | IST-REx-ID: 9873
Quantification of the growth rate reduction as a consequence of age-specific mortality
A. Boehm, M. Arnoldini, T. Bergmiller, T. Röösli, C. Bigosch, M. Ackermann, (2016).
[Published Version] View | Files available | DOI
 
2016 | Journal Article | IST-REx-ID: 5749 | OA
Adaptation to parasites and costs of parasite resistance in mutator and nonmutator bacteria
S. Wielgoss, T. Bergmiller, A.M. Bischofberger, A.R. Hall, Molecular Biology and Evolution 33 (2016) 770–782.
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
2016 | Conference Paper | IST-REx-ID: 1093 | OA
Linear distances between Markov chains
P. Daca, T.A. Henzinger, J. Kretinsky, T. Petrov, in:, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2016.
[Published Version] View | Files available | DOI
 
2016 | Conference Paper | IST-REx-ID: 1234 | OA
Faster statistical model checking for unbounded temporal properties
P. Daca, T.A. Henzinger, J. Kretinsky, T. Petrov, in:, Springer, 2016, pp. 112–129.
[Preprint] View | Files available | DOI | Download Preprint (ext.)
 
2016 | Journal Article | IST-REx-ID: 1243
Bacterial autoimmunity due to a restriction-modification system
M. Pleska, L. Qian, R. Okura, T. Bergmiller, Y. Wakamoto, E. Kussell, C.C. Guet, Current Biology 26 (2016) 404–409.
View | Files available | DOI
 
2016 | Journal Article | IST-REx-ID: 1358 | OA
Intrinsic limits to gene regulation by global crosstalk
T. Friedlander, R. Prizak, C.C. Guet, N.H. Barton, G. Tkačik, Nature Communications 7 (2016).
[Published Version] View | Files available | DOI
 
2015 | Conference Paper | IST-REx-ID: 1430 | OA
First steps towards a runtime comparison of natural and artificial evolution
T. Paixao, D. Sudholt, J. Heredia, B. Trubenova, in:, Proceedings of the 2015 Annual Conference on Genetic and Evolutionary Computation, ACM, 2015, pp. 1455–1462.
[Preprint] View | DOI | Download Preprint (ext.)
 
2015 | Journal Article | IST-REx-ID: 1542 | OA
Toward a unifying framework for evolutionary processes
T. Paixao, G. Badkobeh, N.H. Barton, D. Çörüş, D. Dang, T. Friedrich, P. Lehre, D. Sudholt, A. Sutton, B. Trubenova, Journal of Theoretical Biology 383 (2015) 28–43.
[Published Version] View | Files available | DOI
 
2015 | Journal Article | IST-REx-ID: 1840 | OA
Optimal Kullback-Leibler aggregation via information bottleneck
B. Geiger, T. Petrov, G. Kubin, H. Koeppl, IEEE Transactions on Automatic Control 60 (2015) 1010–1022.
[Preprint] View | DOI | Download Preprint (ext.)
 
2015 | Research Data Reference | IST-REx-ID: 9712
Other fitness models for comparison & for interacting TFBSs
M. Tugrul, T. Paixao, N.H. Barton, G. Tkačik, (2015).
[Published Version] View | Files available | DOI
 
2015 | Research Data Reference | IST-REx-ID: 9719 | OA
Data from: Adaptation to parasites and costs of parasite resistance in mutator and non-mutator bacteria
S. Wielgoss, T. Bergmiller, A.M. Bischofberger, A.R. Hall, (2015).
[Published Version] View | Files available | DOI | Download Published Version (ext.)
 
2015 | Journal Article | IST-REx-ID: 1666 | OA
Dynamics of transcription factor binding site evolution
M. Tugrul, T. Paixao, N.H. Barton, G. Tkačik, PLoS Genetics 11 (2015).
[Published Version] View | Files available | DOI
 
2015 | Conference Paper | IST-REx-ID: 1835 | OA
Model checking gene regulatory networks
M. Giacobbe, C.C. Guet, A. Gupta, T.A. Henzinger, T. Paixao, T. Petrov, 9035 (2015) 469–483.
[Preprint] View | Files available | DOI | Download Preprint (ext.)
 
2014 | Journal Article | IST-REx-ID: 1894 | OA
Functional and bioinformatics analysis of two Campylobacter jejuni homologs of the thiol-disulfide oxidoreductase, DsbA
A. Grabowska, E. Wywiał, S. Dunin Horkawicz, A. Łasica, M. Wösten, A.A. Nagy-Staron, R. Godlewska, K. Bocian Ostrzycka, K. Pieńkowska, P. Łaniewski, J. Bujnicki, J. Van Putten, E. Jagusztyn Krynicka, PLoS One 9 (2014).
[Published Version] View | Files available | DOI
 
2014 | Journal Article | IST-REx-ID: 2056 | OA
Markov chain aggregation and its applications to combinatorial reaction networks
A. Ganguly, T. Petrov, H. Koeppl, Journal of Mathematical Biology 69 (2014) 767–797.
[Submitted Version] View | DOI | Download Submitted Version (ext.)
 
2014 | Journal Article | IST-REx-ID: 2083 | OA
Role of sex and migration in adaptation to sink environments
M. Lagator, A. Morgan, P. Neve, N. Colegrave, Evolution 68 (2014) 2296–2305.
[Published Version] View | Files available | DOI
 
2014 | Research Data Reference | IST-REx-ID: 9747 | OA
Data from: Role of sex and migration in adaptation to sink environments
M. Lagator, A. Morgan, P. Neve, N. Colegrave, (2014).
[Published Version] View | Files available | DOI | Download Published Version (ext.)
 

Filters and Search Terms

type<>research_data

Search

Filter Publications

    • Display / Sort

    Export / Embed