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This work was supported by the Austrian Science Fund (FWF) under projects PAT5044023 and W1250 awarded to C.-P.H.","publisher":"Institute of Science and Technology Austria","corr_author":"1","license":"https://creativecommons.org/licenses/by-sa/4.0/","month":"3","oa":1,"status":"public","acknowledged_ssus":[{"_id":"Bio"},{"_id":"EM-Fac"},{"_id":"ScienComp"},{"_id":"LifeSc"}],"contributor":[{"first_name":"Yann-Edwin","last_name":"Keta","contributor_type":"researcher"},{"last_name":"Henkes","contributor_type":"supervisor","first_name":"Silke "},{"contributor_type":"supervisor","orcid":"0000-0002-0912-4566","last_name":"Heisenberg","id":"39427864-F248-11E8-B48F-1D18A9856A87","first_name":"Carl-Philipp J"},{"first_name":"Edouard B","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","contributor_type":"supervisor","last_name":"Hannezo","orcid":"0000-0001-6005-1561"}],"type":"research_data","year":"2026","file_date_updated":"2026-03-24T07:21:43Z","date_updated":"2026-06-10T09:44:10Z","day":"24","department":[{"_id":"GradSch"},{"_id":"CaHe"},{"_id":"EdHa"}],"has_accepted_license":"1","date_published":"2026-03-24T00:00:00Z","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","article_processing_charge":"No","project":[{"grant_number":"665385","name":"International IST Doctoral Program","_id":"2564DBCA-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"},{"name":"Keratins in epithelial tissue spreading","grant_number":"PAT 5044023","_id":"8f060199-16d5-11f0-9cad-f3253b266c46"},{"call_identifier":"FWF","_id":"252C3B08-B435-11E9-9278-68D0E5697425","name":"Nano-Analytics of Cellular Systems","grant_number":"W1250-B20"}],"title":"Data associated with Keratins coordinate tissue spreading ","citation":{"ieee":"S. Naik, “Data associated with Keratins coordinate tissue spreading .” Institute of Science and Technology Austria, 2026.","chicago":"Naik, Suyash. “Data Associated with Keratins Coordinate Tissue Spreading .” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21137\">https://doi.org/10.15479/AT-ISTA-21137</a>.","apa":"Naik, S. (2026). Data associated with Keratins coordinate tissue spreading . Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21137\">https://doi.org/10.15479/AT-ISTA-21137</a>","ama":"Naik S. Data associated with Keratins coordinate tissue spreading . 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21137\">10.15479/AT-ISTA-21137</a>","short":"S. Naik, (2026).","ista":"Naik S. 2026. Data associated with Keratins coordinate tissue spreading , Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT-ISTA-21137\">10.15479/AT-ISTA-21137</a>.","mla":"Naik, Suyash. <i>Data Associated with Keratins Coordinate Tissue Spreading </i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21137\">10.15479/AT-ISTA-21137</a>."},"doi":"10.15479/AT-ISTA-21137","file":[{"content_type":"application/zip","file_id":"21461","file_size":725916,"access_level":"open_access","relation":"main_file","checksum":"5d1fda7e410f24c311fcf6bcf725698f","description":"Python3 library written in C++20 to integrate vertex models. Please read the readme at https://github.com/yketa/cells/blob/main/README.md for detailed instructions for installation and usage of the code in this repository. 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Apical domain mechanosensation regulates tissue tension homeostasis.","ieee":"N. Hino, T. Kapoor, U. R. Gubbala, E. B. Hannezo, and C.-P. J. Heisenberg, “Apical domain mechanosensation regulates tissue tension homeostasis.” Institute of Science and Technology Austria.","chicago":"Hino, Naoya, Tushna Kapoor, Uday R Gubbala, Edouard B Hannezo, and Carl-Philipp J Heisenberg. “Apical Domain Mechanosensation Regulates Tissue Tension Homeostasis.” Institute of Science and Technology Austria, n.d.","apa":"Hino, N., Kapoor, T., Gubbala, U. R., Hannezo, E. B., &#38; Heisenberg, C.-P. J. (n.d.). Apical domain mechanosensation regulates tissue tension homeostasis. Institute of Science and Technology Austria.","short":"N. Hino, T. Kapoor, U.R. Gubbala, E.B. Hannezo, C.-P.J. Heisenberg, (n.d.).","ista":"Hino N, Kapoor T, Gubbala UR, Hannezo EB, Heisenberg C-PJ. Apical domain mechanosensation regulates tissue tension homeostasis.","mla":"Hino, Naoya, et al. <i>Apical Domain Mechanosensation Regulates Tissue Tension Homeostasis</i>. Institute of Science and Technology Austria."},"project":[{"name":"Keratins in epithelial tissue spreading","grant_number":"PAT 5044023","_id":"8f060199-16d5-11f0-9cad-f3253b266c46"},{"_id":"34dd7f3b-11ca-11ed-8bc3-856f2c87f5da","grant_number":"LTF 16-2022","name":"Mechanosensitive signaling activation in the crosstalk between mechanical force and tissuefluidity"}],"file_date_updated":"2026-07-13T09:16:28Z","date_updated":"2026-07-14T07:07:41Z","day":"14","year":"2026","type":"preprint","language":[{"iso":"eng"}],"date_published":"2026-07-14T00:00:00Z","has_accepted_license":"1","department":[{"_id":"CaHe"},{"_id":"EdHa"},{"_id":"GradSch"}],"month":"07","status":"public","oa":1,"corr_author":"1","dataavailabilitystatement":"The MATLAB code for image analysis, and the full model code, including all parameter values\r\nand condition-specific settings, are available on GitHub at https://github.com/uday2607/EVL-tension-homeostasis.git.","acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"},{"_id":"EM-Fac"}],"ddc":["570"],"_id":"22276","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"OA_place":"publisher","date_created":"2026-07-13T09:03:26Z","keyword":["Epithelial spreading","tissue tension","mechanosensation","aPKC","Kibra","zebrafish"],"publisher":"Institute of Science and Technology Austria","abstract":[{"text":"Tissue tension is a key determinant of tissue shape, and its regulation is essential for both morphogenesis and the maintenance of tissue integrity. During zebrafish embryogenesis, the enveloping layer (EVL) – an epithelial monolayer covering the blastoderm – undergoes extensive spreading that is driven by pulling forces exerted at its margin and more than doubles its surface area. Yet whether and how the EVL actively regulates its tissue tension during this process remains unclear. Here, we show that the EVL maintains constant tissue tension while spreading, and that it achieves this by reducing apical cell contractility in response to the same pulling forces that drive its spreading. We identify a mechanosensitive pathway underlying this response, mediated by the scaffold/adaptor protein Kibra regulating the activity of atypical protein kinase C (aPKC) at the apical domain of EVL cells. Under low mechanical stretch, Kibra forms condensates at the base of actin-based apical projections, where it activates Myosin II to increase apical contractility through aPKC downregulation. As mechanical stretch increases, apical projections disassemble, Kibra condensates dissolve, and aPKC activity rises. Elevated aPKC activity in turn reduces apical contractility by reducing Myosin II activity, thereby maintaining constant tissue tension despite increased mechanical stretch. Together, these findings reveal a mechanosensitive mechanism that enables robust adaptation of tissue tension to changing mechanical stretch, ensuring efficient tissue spreading and morphogenesis.","lang":"eng"}],"acknowledgement":"We thank all members of the Heisenberg group for discussion and feedback on the manuscript, and the Imaging and Optics Facility, the Life Science Support Facility and the Electron Microscopy Facility of the Institute of Science and Technology Austria (ISTA) for their continued support. We are grateful to M. Sonawane (Tata Institute of Fundamental Research, India) for providing the pCS2-HA-aPKC (PKCι)-V260F (DN) and pCS2-HA-aPKC (PKCι)-A122E (CA) plasmids, and to I. Mayer for the discussion. Molecular graphics and analyses were performed with UCSF ChimeraX, developed by the Resource for Biocomputing, Visualization, and Informatics at the University of California, San Francisco, with support from National Institutes of Health R01-GM129325 and the Office of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases. This research was funded in whole or in part by the Austrian Science Fund (FWF; grant no. PAT5044023) to C.-P.H., and by a JSPS Overseas Research Fellowship and an EMBO Postdoctoral Fellowship (ALTF 16-2022) to N.H."},{"oa_version":"Published Version","researchdata_availability":"yes","author":[{"full_name":"Hlavata, Annamaria","last_name":"Hlavata","id":"36062FEC-F248-11E8-B48F-1D18A9856A87","first_name":"Annamaria"},{"full_name":"Neuditschko, Benjamin","last_name":"Neuditschko","first_name":"Benjamin"},{"full_name":"Schellhaas, Ulla","last_name":"Schellhaas","first_name":"Ulla"},{"last_name":"Plaschka","full_name":"Plaschka, Clemens","first_name":"Clemens"},{"first_name":"Franz","full_name":"Herzog, Franz","last_name":"Herzog"},{"first_name":"Carrie A","id":"2CB9DFE2-F248-11E8-B48F-1D18A9856A87","last_name":"Bernecky","orcid":"0000-0003-0893-7036","full_name":"Bernecky, Carrie A"}],"doi":"10.1038/s41467-026-75416-8","biorxivid":1,"DOAJ_listed":"1","external_id":{"biorxivid":["10.64898/2025.12.10.692585"]},"das_tickbox":"1","PlanS_conform":"1","publication_status":"epub_ahead","date_published":"2026-07-13T00:00:00Z","language":[{"iso":"eng"}],"has_accepted_license":"1","department":[{"_id":"CaBe"}],"date_updated":"2026-07-16T11:29:31Z","day":"13","type":"journal_article","year":"2026","publication_identifier":{"eissn":["2041-1723"]},"title":"Structure of cytoplasmic RNA polymerase II","supplementarymaterial":"yes","citation":{"short":"A. Hlavata, B. Neuditschko, U. Schellhaas, C. Plaschka, F. Herzog, C. Bernecky, Nature Communications (2026).","ista":"Hlavata A, Neuditschko B, Schellhaas U, Plaschka C, Herzog F, Bernecky C. 2026. Structure of cytoplasmic RNA polymerase II. Nature Communications.","mla":"Hlavata, Annamaria, et al. “Structure of Cytoplasmic RNA Polymerase II.” <i>Nature Communications</i>, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41467-026-75416-8\">10.1038/s41467-026-75416-8</a>.","apa":"Hlavata, A., Neuditschko, B., Schellhaas, U., Plaschka, C., Herzog, F., &#38; Bernecky, C. (2026). Structure of cytoplasmic RNA polymerase II. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-026-75416-8\">https://doi.org/10.1038/s41467-026-75416-8</a>","ama":"Hlavata A, Neuditschko B, Schellhaas U, Plaschka C, Herzog F, Bernecky C. Structure of cytoplasmic RNA polymerase II. <i>Nature Communications</i>. 2026. doi:<a href=\"https://doi.org/10.1038/s41467-026-75416-8\">10.1038/s41467-026-75416-8</a>","chicago":"Hlavata, Annamaria, Benjamin Neuditschko, Ulla Schellhaas, Clemens Plaschka, Franz Herzog, and Carrie Bernecky. “Structure of Cytoplasmic RNA Polymerase II.” <i>Nature Communications</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41467-026-75416-8\">https://doi.org/10.1038/s41467-026-75416-8</a>.","ieee":"A. Hlavata, B. Neuditschko, U. Schellhaas, C. Plaschka, F. Herzog, and C. Bernecky, “Structure of cytoplasmic RNA polymerase II,” <i>Nature Communications</i>. Springer Nature, 2026."},"main_file_link":[{"url":"https://doi.org/10.1038/s41467-026-75416-8","open_access":"1"}],"article_processing_charge":"Yes","OA_type":"gold","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"Springer Nature","article_type":"original","abstract":[{"text":"RNA polymerase II (Pol II) must be assembled in the cytoplasm before it enters the nucleus, where it transcribes protein-coding genes. Although transcription by Pol II is intensively studied, how this central multi-subunit enzyme is made and the role of dedicated assembly factors remains unclear. Here, we report the integrative structural analysis of a native human Pol II from the cytoplasm captured near the end of biogenesis. The complex contains Gdown1 and three biogenesis factors – RPAP2 and the critical small GTPases GPN1 and GPN3. Cryo-EM analysis of the complex reveals how Gdown1 and RPAP2 associate with Pol II and prevent the premature association of transcription factors. Further biochemical and cryo-EM analysis reveals how RPAP2 tethers GPN1–GPN3 to the complex and how the assembly of the RPAP2–GPN1–GPN3 complex is controlled by GTP hydrolysis. The combined results uncover a network of interactions that chaperone cytoplasmic Pol II to prevent aberrant interactions, reveal a molecular switch regulating biogenesis factor association, and suggest a general mechanism for the action of GPN-loop GTPase family of enzymes.","lang":"eng"}],"acknowledgement":"We thank A. Salmazo for assistance with Pol II purification. We thank staff at the Vienna BioCenter Core Facilities (VBCF) Proteomics facility for immunoprecipitation-mass spectrometry analysis, and J.A. Stopp for assistance with IP-MS data visualization. This research was further supported by the Scientific Service Units (SSUs) of ISTA through resources provided by the Lab Support Facility (LSF), Electron Microscopy Facility (EMF), Scientific Computing (SciComp), and the Preclinical Facility (PCF). F.H. was funded by the Endowed Professorship of the Lower Austria Research Funding Agency (GFF NÖ) and by the Austrian Research Promotion Agency (FFG) through the COIN Establishment Grant n.o. 45624401.","OA_place":"publisher","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"_id":"22333","date_created":"2026-07-14T07:27:59Z","scopus_import":"1","acknowledged_ssus":[{"_id":"LifeSc"},{"_id":"EM-Fac"},{"_id":"ScienComp"},{"_id":"PreCl"}],"dataavailabilitystatement":"The\r\nc ryo EM maps generated in this study were deposited to the EM Data Bank under the\r\naccession codes: EMD 55583 [https://www.ebi.ac.uk/pdbe/entry/emdb/EMD 55583\r\n(Pol II Gdown1 RPAP2 composite map), EMD 55578\r\n[https://www.ebi.ac.uk/pdbe/entry/emdb/EMD 55578 Pol II Gdown1 RPAP2 Pol II core\r\nmap EMD 55579 [https://www.ebi.ac.uk/pdbe/entry/emdb/EMD 55579 Pol II\r\nGdown1 RPAP2 Pol II stalk map EMD 55580\r\n[https://www.ebi.ac.uk/pdbe/entry/emdb/EMD 55580 Pol II Gdown1 RPAP2 RPAP2\r\nmap EMD 55581 [https://www.ebi.ac.uk/pdbe/entry/emdb/EMD 55 581 Pol II\r\nGdown1 RPAP2 Gdown1 N terminus map EMD 55582\r\n[https://www.ebi.ac.uk/pdbe/entry/emdb/EMD 55582 Pol II Gdown1 RPAP2 Gdown1\r\nC terminus map and EMD 55585 [https://www.ebi.ac.uk/pdbe/entry/emdb/EMD\r\n55585 RPAP2 GPN1 GPN3 map Model coordi nates were deposited to the PDBe under\r\nthe accession codes: 9T5H [http://doi.org/10.2210/pdb 9T5H / (Pol II Gdown1\r\nRPAP2 complex structure) and 9T5J [http://doi.org/10.2210/pdb 9T5H / (GPN1\r\nGPN3 RPAP2 structure). Immunoprecipitation mass spectrometry and crosslinking mass\r\nspectrometry proteomics data have been deposited to the ProteomeXchange Consortium\r\nvia the PRIDE partner repository with the dataset identifiers PXD071638\r\n[http://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD 071638 and\r\nP XD070852\r\n[http://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD 070852\r\nAlphaFold3 structure predictions have been deposited to the Zenodo repository\r\nhttps://doi.org/10.5281/zenodo.20687910 P reviously published model coordinates\r\nwere utilized and are available at the PDB under the accession codes 8QEP\r\n[http://doi.org/10.2210/pdb 8QEP / 9BZ 0 [http://doi.org/10.2210/pdb 9BZ 0 /\r\nand 7B7U [http://doi.org/10.2210/pdb 7B7U / Source Data are provided with this\r\npaper.","quality_controlled":"1","ddc":["570"],"publication":"Nature Communications","month":"07","oa":1,"status":"public","corr_author":"1"},{"oa_version":"Published Version","author":[{"first_name":"Xingqi","full_name":"Chang, Xingqi","last_name":"Chang"},{"last_name":"Escudero","full_name":"Escudero, Carlos","first_name":"Carlos"},{"full_name":"Black, Ashley P.","last_name":"Black","first_name":"Ashley P."},{"first_name":"Sharona","id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc","last_name":"Horta","full_name":"Horta, Sharona"},{"first_name":"Elías","full_name":"Martínez, Elías","last_name":"Martínez"},{"full_name":"Lu, Xuan","last_name":"Lu","first_name":"Xuan"},{"first_name":"Jordi","full_name":"Llorca, Jordi","last_name":"Llorca"},{"first_name":"Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87","last_name":"Ibáñez","orcid":"0000-0001-5013-2843","full_name":"Ibáñez, Maria"},{"last_name":"Biendicho","full_name":"Biendicho, Jordi Jacas","first_name":"Jordi Jacas"},{"first_name":"Andreu","full_name":"Cabot, Andreu","last_name":"Cabot"}],"file":[{"checksum":"37adc3eff9ad9f8f9b55cfe66883f36d","file_id":"22387","file_size":6353217,"content_type":"application/pdf","relation":"main_file","access_level":"open_access","creator":"dernst","file_name":"2026_AdvancedScience_Chang.pdf","date_updated":"2026-07-23T06:15:51Z","date_created":"2026-07-23T06:15:51Z","success":1}],"researchdata_availability":"upon request","doi":"10.1002/advs.202515962","pmid":1,"DOAJ_listed":"1","external_id":{"pmid":["41388041"]},"das_tickbox":"1","intvolume":"        13","PlanS_conform":"1","publication_status":"published","article_number":"e15962","issue":"11","date_published":"2026-02-23T00:00:00Z","language":[{"iso":"eng"}],"has_accepted_license":"1","department":[{"_id":"MaIb"}],"day":"23","date_updated":"2026-07-23T06:18:43Z","file_date_updated":"2026-07-23T06:15:51Z","publication_identifier":{"eissn":["2198-3844"]},"year":"2026","type":"journal_article","supplementarymaterial":"yes","citation":{"ama":"Chang X, Escudero C, Black AP, et al. Mitigating the rock-salt phase transformation in disordered LNMO through synergetic solid-state AlF3/LiF modifications. <i>Advanced Science</i>. 2026;13(11). doi:<a href=\"https://doi.org/10.1002/advs.202515962\">10.1002/advs.202515962</a>","ieee":"X. Chang <i>et al.</i>, “Mitigating the rock-salt phase transformation in disordered LNMO through synergetic solid-state AlF3/LiF modifications,” <i>Advanced Science</i>, vol. 13, no. 11. Wiley, 2026.","apa":"Chang, X., Escudero, C., Black, A. P., Horta, S., Martínez, E., Lu, X., … Cabot, A. (2026). Mitigating the rock-salt phase transformation in disordered LNMO through synergetic solid-state AlF3/LiF modifications. <i>Advanced Science</i>. Wiley. <a href=\"https://doi.org/10.1002/advs.202515962\">https://doi.org/10.1002/advs.202515962</a>","chicago":"Chang, Xingqi, Carlos Escudero, Ashley P. Black, Sharona Horta, Elías Martínez, Xuan Lu, Jordi Llorca, Maria Ibáñez, Jordi Jacas Biendicho, and Andreu Cabot. “Mitigating the Rock-Salt Phase Transformation in Disordered LNMO through Synergetic Solid-State AlF3/LiF Modifications.” <i>Advanced Science</i>. Wiley, 2026. <a href=\"https://doi.org/10.1002/advs.202515962\">https://doi.org/10.1002/advs.202515962</a>.","short":"X. Chang, C. Escudero, A.P. Black, S. Horta, E. Martínez, X. Lu, J. Llorca, M. Ibáñez, J.J. Biendicho, A. Cabot, Advanced Science 13 (2026).","ista":"Chang X, Escudero C, Black AP, Horta S, Martínez E, Lu X, Llorca J, Ibáñez M, Biendicho JJ, Cabot A. 2026. Mitigating the rock-salt phase transformation in disordered LNMO through synergetic solid-state AlF3/LiF modifications. Advanced Science. 13(11), e15962.","mla":"Chang, Xingqi, et al. “Mitigating the Rock-Salt Phase Transformation in Disordered LNMO through Synergetic Solid-State AlF3/LiF Modifications.” <i>Advanced Science</i>, vol. 13, no. 11, e15962, Wiley, 2026, doi:<a href=\"https://doi.org/10.1002/advs.202515962\">10.1002/advs.202515962</a>."},"title":"Mitigating the rock-salt phase transformation in disordered LNMO through synergetic solid-state AlF3/LiF modifications","volume":13,"project":[{"name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery","_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A"}],"article_processing_charge":"Yes","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_type":"gold","publisher":"Wiley","abstract":[{"lang":"eng","text":"High-voltage disordered spinel LiNi0.5Mn1.5O4 is a promising cathode material for high power density in lithium-ion batteries. However, it suffers from poor cycle life associated with the rock-salt phase transformation. This study presents a straightforward synthesis approach to enhance the electrochemical performance of LiNi0.5Mn1.5O4 through a synergistic solid-state modification with LiF and AlF3. This dual modification promotes rapid Li⁺ diffusion, enables near-complete delithiation/lithiation, approaching the theoretical capacity of disordered LiNi0.5Mn1.5O4, and, more importantly, effectively mitigates the formation of the rock-salt phase, thereby enhancing structural stability, as confirmed by operando X-ray absorption spectroscopy (XAS) and synchrotron X-ray diffraction (SXRD). As a result, the optimized LiNi0.5Mn1.5O4 (10 mg AlF3 + 30 mg LiF) delivers high reversible capacities of 142.1, 139.1, 129.2, 121.6, 110.3, 93.5, and 76.1 mAh∙g−1 at 0.2C, 0.5C, 1.0C, 2.0C, 3.0C, 4.0C, and 5.0C, respectively. Full cells using graphite as the anode and a high-loading cathode exhibit excellent cycling performance. They retain 80% of their capacity after 200 cycles at 0.5C within a voltage window of 3.5–4.9 V with cathode loading of 11 mg∙cm−2. The findings of this study will significantly advance high-power LiNi0.5Mn1.5O4 materials, offering improved battery life and thereby enhancing their potential for practical applications."}],"article_type":"original","acknowledgement":"This work was supported by the European Commission-financed project IntelLigent (HORIZON-CL5-2021-D2-01-02) with project ID number 101069765. In collaboration with ALBA staff, the operando SXRD and XAS experiments were performed at BL-16-NOTOS beamline at ALBA Synchrotron Light Source (experiment number: 2023097765). This research was supported by the Scientific Service Units (SSU) of the Institute of Science and Technology Austria (ISTA) through resources provided by the Electron Microscopy Facility (EMF) and the Nanofabrication Facility (NFF), and M.I. and S.H. acknowledge financial support from ISTA and the Werner Siemens Foundation. Jordi Jacas Biendicho acknowledges the fellowship RYC2021-034994-I, funded by MICIU/AEI/10.13039/501100011033 and the European Union «NextGenerationEU»/PRTR». Jordi Llorca is a Serra Húnter Fellow and is grateful to projects MICIN/AEI/FEDER PID2021-124572OB-C31 and Maria de Maeztu Units of Excellence Programme CEX2023-001300-M, and GC 2021 SGR 01061.","scopus_import":"1","date_created":"2025-12-21T23:01:35Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"OA_place":"publisher","_id":"20851","keyword":["disordered spinel LiNi0.5Mn1.5O4 (LNMO)","generation 3b batteries","operando SXRD","operando XAS","rock-salt","solid-state synthesis"],"dataavailabilitystatement":"The data that support the ﬁndings of this study are available from the corresponding author upon reasonable request","acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"NanoFab"}],"ddc":["540"],"quality_controlled":"1","status":"public","oa":1,"publication":"Advanced Science","month":"02"},{"file":[{"date_updated":"2026-07-23T11:40:34Z","success":1,"date_created":"2026-07-23T11:40:34Z","creator":"dernst","file_name":"2026_AdvancedFunctionalMat_He.pdf","checksum":"b102207b2343e6e7dba00870bfe362ea","file_id":"22397","file_size":5734587,"content_type":"application/pdf","relation":"main_file","access_level":"open_access"}],"author":[{"first_name":"Ren","full_name":"He, Ren","last_name":"He"},{"id":"BB243B88-D767-11E9-B658-BC13E6697425","first_name":"Seungho","full_name":"Lee, Seungho","last_name":"Lee","orcid":"0000-0002-6962-8598"},{"full_name":"Ding, Yang","last_name":"Ding","first_name":"Yang"},{"first_name":"Chen","last_name":"Huang","full_name":"Huang, Chen"},{"first_name":"Xuan","last_name":"Lu","full_name":"Lu, Xuan"},{"first_name":"Lirong","full_name":"Zheng, Lirong","last_name":"Zheng"},{"first_name":"Ao","full_name":"Yu, Ao","last_name":"Yu"},{"first_name":"Chaoyue","last_name":"Zhang","full_name":"Zhang, Chaoyue"},{"last_name":"Li","full_name":"Li, Canhuang","first_name":"Canhuang"},{"first_name":"Xiaoyu","full_name":"Bi, Xiaoyu","last_name":"Bi"},{"first_name":"Yaqiang","last_name":"Li","full_name":"Li, Yaqiang"},{"last_name":"Liao","full_name":"Liao, Yaqi","first_name":"Yaqi"},{"last_name":"Li","full_name":"Li, Junshan","first_name":"Junshan"},{"last_name":"Ostovari Moghaddam","full_name":"Ostovari Moghaddam, Ahmad","first_name":"Ahmad"},{"last_name":"Yernar","full_name":"Yernar, Salimov","first_name":"Salimov"},{"last_name":"Xu","full_name":"Xu, Ying","first_name":"Ying"},{"first_name":"Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87","last_name":"Ibáñez","orcid":"0000-0001-5013-2843","full_name":"Ibáñez, Maria"},{"last_name":"Zhang","full_name":"Zhang, Chaoqi","first_name":"Chaoqi"},{"first_name":"Linlin","full_name":"Yang, Linlin","last_name":"Yang"},{"full_name":"Zhou, Yingtang","last_name":"Zhou","first_name":"Yingtang"},{"first_name":"Andreu","last_name":"Cabot","full_name":"Cabot, Andreu"}],"researchdata_availability":"upon request","doi":"10.1002/adfm.202513859","oa_version":"Published Version","external_id":{"isi":["001544757200001"]},"publication_status":"published","article_number":"e13859","issue":"5","das_tickbox":"1","intvolume":"        36","date_updated":"2026-07-23T11:42:17Z","day":"15","file_date_updated":"2026-07-23T11:40:34Z","type":"journal_article","publication_identifier":{"eissn":["1616-3028"],"issn":["1616-301X"]},"year":"2026","language":[{"iso":"eng"}],"date_published":"2026-01-15T00:00:00Z","department":[{"_id":"MaIb"}],"has_accepted_license":"1","article_processing_charge":"Yes (in subscription journal)","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_type":"hybrid","supplementarymaterial":"no","citation":{"apa":"He, R., Lee, S., Ding, Y., Huang, C., Lu, X., Zheng, L., … Cabot, A. (2026). Amorphous high entropy alloy nanosheets enabling robust Li–S batteries. <i>Advanced Functional Materials</i>. Wiley. <a href=\"https://doi.org/10.1002/adfm.202513859\">https://doi.org/10.1002/adfm.202513859</a>","ieee":"R. He <i>et al.</i>, “Amorphous high entropy alloy nanosheets enabling robust Li–S batteries,” <i>Advanced Functional Materials</i>, vol. 36, no. 5. Wiley, 2026.","chicago":"He, Ren, Seungho Lee, Yang Ding, Chen Huang, Xuan Lu, Lirong Zheng, Ao Yu, et al. “Amorphous High Entropy Alloy Nanosheets Enabling Robust Li–S Batteries.” <i>Advanced Functional Materials</i>. Wiley, 2026. <a href=\"https://doi.org/10.1002/adfm.202513859\">https://doi.org/10.1002/adfm.202513859</a>.","ama":"He R, Lee S, Ding Y, et al. Amorphous high entropy alloy nanosheets enabling robust Li–S batteries. <i>Advanced Functional Materials</i>. 2026;36(5). doi:<a href=\"https://doi.org/10.1002/adfm.202513859\">10.1002/adfm.202513859</a>","ista":"He R, Lee S, Ding Y, Huang C, Lu X, Zheng L, Yu A, Zhang C, Li C, Bi X, Li Y, Liao Y, Li J, Ostovari Moghaddam A, Yernar S, Xu Y, Ibáñez M, Zhang C, Yang L, Zhou Y, Cabot A. 2026. Amorphous high entropy alloy nanosheets enabling robust Li–S batteries. Advanced Functional Materials. 36(5), e13859.","mla":"He, Ren, et al. “Amorphous High Entropy Alloy Nanosheets Enabling Robust Li–S Batteries.” <i>Advanced Functional Materials</i>, vol. 36, no. 5, e13859, Wiley, 2026, doi:<a href=\"https://doi.org/10.1002/adfm.202513859\">10.1002/adfm.202513859</a>.","short":"R. He, S. Lee, Y. Ding, C. Huang, X. Lu, L. Zheng, A. Yu, C. Zhang, C. Li, X. Bi, Y. Li, Y. Liao, J. Li, A. Ostovari Moghaddam, S. Yernar, Y. Xu, M. Ibáñez, C. Zhang, L. Yang, Y. Zhou, A. Cabot, Advanced Functional Materials 36 (2026)."},"title":"Amorphous high entropy alloy nanosheets enabling robust Li–S batteries","volume":36,"project":[{"name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery","_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A"}],"date_created":"2025-08-17T22:01:37Z","scopus_import":"1","tmp":{"short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"_id":"20191","OA_place":"publisher","keyword":["amorphous","high entropy alloy","in situ electrochemical impedance spec-troscopy","in situ Raman","Li–S batteries"],"publisher":"Wiley","article_type":"original","acknowledgement":"The authors acknowledge support from the 2BoSS project of the ERA-MIN3 program with the Spanish grant number PCI2022-132985/AEI/10.13039/50110001103, and funding from Generalitat de Catalunya 2021SGR01581 and European Union NextGenerationEU/PRTR. L.Yang, C.Huang, X.Lu, A.Yu, C.Li, J.Yu, and X.Bi thank the China Scholarship Council (CSC) for the scholarship support. This research was supported by the Scientific Service Units (SSU) of ISTA through resources provided by the Electron Microscopy Facility (EMF), and by the Werner Siemens Foundation (WSS) for financial support.","abstract":[{"lang":"eng","text":"High-entropy alloys (HEAs) show great potential for catalyzing complex multi-step reactions, but optimizing their parameters, i.e., composition, but also their crystallinity and morphology, remains a significant challenge. In this study, FeCoNiMoW HEAs are synthesized into either amorphous nanosheets (HEANS) or crystalline nanoparticles (HEANP), which are then used to catalyze the lithium–sulfur (Li–S) reaction of Li–S batteries (LSBs). Evaluations in symmetric cells, coin cells, and pouch cells reveal that HEANS significantly enhance LSB performance, achieving initial discharge capacities up to 1632 mAh g−1. The batteries also exhibit excellent cycling stability over 1000 cycles at 3Cand maintain high-rate performance up to 10C with a capacity of 614 mAh g−1. Comprehensive in situ analyses and density functional theory calculations demonstrate that amorphous HEANS provide more active sites, better ionic conductivity and stronger chemical interactions with lithium polysulfides (LiPS). These properties effectively suppress the shuttle effect, promote the complete S8 → Li2S conversion by reducing the impedance of the solid-electrolyte interphase, and accelerate the Li2S4 → Li2S2 step by lowering the nucleation energy barrier. Overall, this study highlights the superior catalytic properties of amorphous 2D HEAs in LSBs and offers new insights into the mechanisms of LiPS conversion."}],"status":"public","oa":1,"publication":"Advanced Functional Materials","month":"01","isi":1,"license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","dataavailabilitystatement":"The data that support the ﬁndings of this study are available from the cor-responding authors upon reasonable request.","acknowledged_ssus":[{"_id":"EM-Fac"}],"quality_controlled":"1","ddc":["540"]},{"oa_version":"Published Version","researchdata_availability":"upon request","author":[{"first_name":"Changwei","last_name":"Shi","full_name":"Shi, Changwei"},{"first_name":"Sharona","id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc","last_name":"Horta","full_name":"Horta, Sharona"},{"first_name":"Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5013-2843","last_name":"Ibáñez","full_name":"Ibáñez, Maria"},{"first_name":"Tanja","full_name":"Kallio, Tanja","last_name":"Kallio"},{"first_name":"Paulina R.","last_name":"Martínez-Alanis","full_name":"Martínez-Alanis, Paulina R."},{"first_name":"Xiang","full_name":"Wang, Xiang","last_name":"Wang"},{"first_name":"Andreu","full_name":"Cabot, Andreu","last_name":"Cabot"}],"file":[{"file_size":8345535,"file_id":"22418","content_type":"application/pdf","relation":"main_file","access_level":"open_access","checksum":"c47f1704be452cdefb2b930884693578","date_created":"2026-07-27T11:03:37Z","success":1,"date_updated":"2026-07-27T11:03:37Z","file_name":"2026_ChemicalEngineeringScience_Shi.pdf","creator":"dernst"}],"doi":"10.1016/j.ces.2026.123348","intvolume":"       324","das_tickbox":"1","PlanS_conform":"1","article_number":"123348","publication_status":"published","title":"Hydrogen induced palladium-based heterojunction electrocatalysts to enhance the oxygen reduction reaction performance","supplementarymaterial":"yes","citation":{"mla":"Shi, Changwei, et al. “Hydrogen Induced Palladium-Based Heterojunction Electrocatalysts to Enhance the Oxygen Reduction Reaction Performance.” <i>Chemical Engineering Science</i>, vol. 324, 123348, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.ces.2026.123348\">10.1016/j.ces.2026.123348</a>.","ista":"Shi C, Horta S, Ibáñez M, Kallio T, Martínez-Alanis PR, Wang X, Cabot A. 2026. Hydrogen induced palladium-based heterojunction electrocatalysts to enhance the oxygen reduction reaction performance. Chemical Engineering Science. 324, 123348.","short":"C. Shi, S. Horta, M. Ibáñez, T. Kallio, P.R. Martínez-Alanis, X. Wang, A. Cabot, Chemical Engineering Science 324 (2026).","ama":"Shi C, Horta S, Ibáñez M, et al. Hydrogen induced palladium-based heterojunction electrocatalysts to enhance the oxygen reduction reaction performance. <i>Chemical Engineering Science</i>. 2026;324. doi:<a href=\"https://doi.org/10.1016/j.ces.2026.123348\">10.1016/j.ces.2026.123348</a>","apa":"Shi, C., Horta, S., Ibáñez, M., Kallio, T., Martínez-Alanis, P. R., Wang, X., &#38; Cabot, A. (2026). Hydrogen induced palladium-based heterojunction electrocatalysts to enhance the oxygen reduction reaction performance. <i>Chemical Engineering Science</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.ces.2026.123348\">https://doi.org/10.1016/j.ces.2026.123348</a>","chicago":"Shi, Changwei, Sharona Horta, Maria Ibáñez, Tanja Kallio, Paulina R. Martínez-Alanis, Xiang Wang, and Andreu Cabot. “Hydrogen Induced Palladium-Based Heterojunction Electrocatalysts to Enhance the Oxygen Reduction Reaction Performance.” <i>Chemical Engineering Science</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.ces.2026.123348\">https://doi.org/10.1016/j.ces.2026.123348</a>.","ieee":"C. Shi <i>et al.</i>, “Hydrogen induced palladium-based heterojunction electrocatalysts to enhance the oxygen reduction reaction performance,” <i>Chemical Engineering Science</i>, vol. 324. Elsevier, 2026."},"project":[{"name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery","_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A"}],"volume":324,"article_processing_charge":"Yes (in subscription journal)","OA_type":"hybrid","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","language":[{"iso":"eng"}],"date_published":"2026-04-01T00:00:00Z","department":[{"_id":"MaIb"}],"has_accepted_license":"1","file_date_updated":"2026-07-27T11:03:37Z","date_updated":"2026-07-27T11:03:48Z","day":"01","year":"2026","publication_identifier":{"issn":["1873-4405"],"eissn":["0009-2509"]},"type":"journal_article","dataavailabilitystatement":"Data will be made available on request.","acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"NanoFab"}],"ddc":["540"],"quality_controlled":"1","month":"04","publication":"Chemical Engineering Science","status":"public","oa":1,"publisher":"Elsevier","abstract":[{"text":"The oxygen reduction reaction (ORR) remains a critical bottleneck in fuel cells and metal-air batteries due to the lack of highly efficient electrocatalysts. Here, we report a simple strategy for synthesizing a palladium-based heterostructured electrocatalyst supported on a carbon nitride matrix (PdH-Pd@CN), which exhibits remarkable ORR activity with a half-wave potential of 0.91 V and excellent durability in 0.1 M KOH. Within the heterostructure, hydrogen intercalation expands the Pd lattice, while interstitial hydrogen doping facilitates charge transfer from Pd to H owing to their electronegativity difference. These synergistic effects modulate the electronic structure, thereby enhancing both activity and stability. When employed in Zn-air batteries, PdH-Pd@CN delivers a maximum power density of 176 mW cm− (Liu et al., 2025) and capacity of 805 mAh g− (Sun et al., 2021) Zn. These findings demonstrate the strong potential of PdH-Pd@CN as an efficient ORR electrocatalyst for next-generation metal-air batteries and related energy technologies.","lang":"eng"}],"article_type":"original","acknowledgement":"The authors thank the support from the National Natural Science Foundation of China (NSFC) (Grants No. 22302151) and Natural Science Foundation of Hubei Province (Grants No. 2024AFB755, 2024AFB267), Key Project of Hubei Provincial Department of Education Scientific Research Plan (F2023007). This work is supported by funding from Shandong Provincial Key Laboratory of MonocrystallineSilicon Semiconductor Materials and Technology (2025KFKT021). This research was supported by the Scientific Service Units (SSU) of ISTA Austria through resources provided by the Electron Microscopy Facility (EMF) and the Nanofabrication Facility (NNF). “M.I. and S.H. acknowledge financial support from ISTA and the Werner Siemens Foundation.”","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"_id":"21037","OA_place":"publisher","scopus_import":"1","date_created":"2026-01-25T23:01:39Z"},{"article_processing_charge":"Yes (via OA deal)","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_type":"hybrid","supplementarymaterial":"yes","citation":{"short":"D.B. Grober, T. Dhar, D. Saintillan, J.A. Palacci, Nature Physics 22 (2026) 620–627.","mla":"Grober, Daniel B., et al. “The Hydrodynamic Torque Dipole from Rotary Bacterial Flagella Powers Symmetric Discs.” <i>Nature Physics</i>, vol. 22, Springer Nature, 2026, pp. 620–27, doi:<a href=\"https://doi.org/10.1038/s41567-026-03189-4\">10.1038/s41567-026-03189-4</a>.","ista":"Grober DB, Dhar T, Saintillan D, Palacci JA. 2026. The hydrodynamic torque dipole from rotary bacterial flagella powers symmetric discs. Nature Physics. 22, 620–627.","apa":"Grober, D. B., Dhar, T., Saintillan, D., &#38; Palacci, J. A. (2026). The hydrodynamic torque dipole from rotary bacterial flagella powers symmetric discs. <i>Nature Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41567-026-03189-4\">https://doi.org/10.1038/s41567-026-03189-4</a>","chicago":"Grober, Daniel B, Tanumoy Dhar, David Saintillan, and Jérémie A Palacci. “The Hydrodynamic Torque Dipole from Rotary Bacterial Flagella Powers Symmetric Discs.” <i>Nature Physics</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41567-026-03189-4\">https://doi.org/10.1038/s41567-026-03189-4</a>.","ama":"Grober DB, Dhar T, Saintillan D, Palacci JA. The hydrodynamic torque dipole from rotary bacterial flagella powers symmetric discs. <i>Nature Physics</i>. 2026;22:620-627. doi:<a href=\"https://doi.org/10.1038/s41567-026-03189-4\">10.1038/s41567-026-03189-4</a>","ieee":"D. B. Grober, T. Dhar, D. Saintillan, and J. A. Palacci, “The hydrodynamic torque dipole from rotary bacterial flagella powers symmetric discs,” <i>Nature Physics</i>, vol. 22. Springer Nature, pp. 620–627, 2026."},"title":"The hydrodynamic torque dipole from rotary bacterial flagella powers symmetric discs","volume":22,"project":[{"_id":"bdac72da-d553-11ed-ba76-eae56e802b74","name":"VULCAN: matter, powered from within","grant_number":"101086998"}],"day":"01","date_updated":"2026-07-27T12:29:45Z","file_date_updated":"2026-07-27T12:28:27Z","year":"2026","type":"journal_article","publication_identifier":{"eissn":["1745-2481"],"issn":["1745-2473"]},"date_published":"2026-04-01T00:00:00Z","language":[{"iso":"eng"}],"has_accepted_license":"1","department":[{"_id":"JePa"}],"status":"public","oa":1,"publication":"Nature Physics","month":"04","corr_author":"1","acknowledged_ssus":[{"_id":"NanoFab"},{"_id":"EM-Fac"}],"dataavailabilitystatement":"The datasets generated and analysed during the current study are openly available via Zenodo at https://doi.org/10.5281/zenodo.15236674 (ref. 32). All data are released under the CC-BY 4.0 licence. For any further questions about data access or reuse, please contact the corresponding author.","quality_controlled":"1","ddc":["570","530"],"scopus_import":"1","page":"620-627","date_created":"2026-04-12T22:01:51Z","_id":"21721","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"OA_place":"publisher","publisher":"Springer Nature","acknowledgement":"We thank E. Krasnopeeva for help with the bacterial culture, motility and genetic engineering. We thank Q. Martinet for help with the experimental design, F. Pertl for atomic force microscopy measurements and S. Hajek for the scanning electron microscopy imaging. This project has received funding from the European Research Council under the European Union’s Horizon Europe research and innovation programme (VULCAN, 101086998). The views and opinions expressed are, however, those of the authors only and do not necessarily reflect those of the European Union or the European Research Council Executive Agency. Neither the European Union nor the granting authority can be held responsible for them. J.P. thanks the Nanofabrication and Electron Microscopy Shared Scientific Units of ISTA for support. Open access funding provided by Institute of Science and Technology (IST Austria).","abstract":[{"text":"Swimming bacteria move through a fluid by actuating their moving body parts. They are force-free and can be described as hydrodynamic force dipoles: pushers or pullers. This modelling description is broadly used in biological physics and active matter research, and it has successfully predicted, for example, the superfluid behaviour of suspensions of pushers or the bend instability and emergence of turbulent flows in active nematics. However, this description accounts only for the translational motion of the swimming body and neglects the effects of hydrodynamic torque dipoles, which are relevant to bacteria with rotary motor-driven flagella, such as swimming Escherichia coli. Here we show that the torque dipole of confined swimming E. coli can power the persistent rotation of symmetric discs. The torque dipole leads to a traction force on the discs, an additive mechanism that is both contactless and independent of the orientation of the bacteria. Our results indicate that the torque dipole of swimming E. coli is notable in confined geometries, which is relevant to bacterial transport through porous materials, biofilms and the development of chiral fluids.","lang":"eng"}],"article_type":"original","external_id":{"pmid":["42006933"]},"pmid":1,"author":[{"id":"c692f879-718d-11ee-81f0-da7caa79c783","first_name":"Daniel B","full_name":"Grober, Daniel B","last_name":"Grober"},{"first_name":"Tanumoy","full_name":"Dhar, Tanumoy","last_name":"Dhar"},{"first_name":"David","last_name":"Saintillan","full_name":"Saintillan, David"},{"first_name":"Jérémie A","id":"8fb92548-2b22-11eb-b7c1-a3f0d08d7c7d","last_name":"Palacci","orcid":"0000-0002-7253-9465","full_name":"Palacci, Jérémie A"}],"file":[{"access_level":"open_access","relation":"main_file","content_type":"application/pdf","file_id":"22429","file_size":2960392,"checksum":"bb28ed456cdd288d97854b084dd4b2e1","date_created":"2026-07-27T12:28:27Z","date_updated":"2026-07-27T12:28:27Z","success":1,"file_name":"2026_NaturePhysics_Grober.pdf","creator":"dernst"}],"researchdata_availability":"yes","doi":"10.1038/s41567-026-03189-4","oa_version":"Published Version","PlanS_conform":"1","publication_status":"published","das_tickbox":"1","intvolume":"        22"},{"department":[{"_id":"Bio"},{"_id":"CaHe"},{"_id":"EdHa"}],"has_accepted_license":"1","language":[{"iso":"eng"}],"date_published":"2026-07-17T00:00:00Z","publication_identifier":{"eissn":["2041-1723"]},"type":"journal_article","year":"2026","day":"17","date_updated":"2026-07-29T10:33:31Z","file_date_updated":"2026-07-29T10:27:25Z","volume":17,"project":[{"_id":"8f060199-16d5-11f0-9cad-f3253b266c46","grant_number":"PAT 5044023","name":"Keratins in epithelial tissue spreading"},{"name":"Nano-Analytics of Cellular Systems","grant_number":"W1250-B20","call_identifier":"FWF","_id":"252C3B08-B435-11E9-9278-68D0E5697425"}],"supplementarymaterial":"yes","citation":{"short":"S. Naik, Y.-E. Keta, K. Pranjic-Ferscha, E.B. Hannezo, S. Henkes, C.-P.J. Heisenberg, Nature Communications 17 (2026).","mla":"Naik, Suyash, et al. “Keratins Coordinate Tissue Spreading by Balancing Spreading Forces with Tissue Material Properties.” <i>Nature Communications</i>, vol. 17, 6499, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41467-026-72366-z\">10.1038/s41467-026-72366-z</a>.","ista":"Naik S, Keta Y-E, Pranjic-Ferscha K, Hannezo EB, Henkes S, Heisenberg C-PJ. 2026. Keratins coordinate tissue spreading by balancing spreading forces with tissue material properties. Nature Communications. 17, 6499.","chicago":"Naik, Suyash, Yann-Edwin Keta, Kornelija Pranjic-Ferscha, Edouard B Hannezo, Silke Henkes, and Carl-Philipp J Heisenberg. “Keratins Coordinate Tissue Spreading by Balancing Spreading Forces with Tissue Material Properties.” <i>Nature Communications</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41467-026-72366-z\">https://doi.org/10.1038/s41467-026-72366-z</a>.","apa":"Naik, S., Keta, Y.-E., Pranjic-Ferscha, K., Hannezo, E. B., Henkes, S., &#38; Heisenberg, C.-P. J. (2026). Keratins coordinate tissue spreading by balancing spreading forces with tissue material properties. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-026-72366-z\">https://doi.org/10.1038/s41467-026-72366-z</a>","ieee":"S. Naik, Y.-E. Keta, K. Pranjic-Ferscha, E. B. Hannezo, S. Henkes, and C.-P. J. Heisenberg, “Keratins coordinate tissue spreading by balancing spreading forces with tissue material properties,” <i>Nature Communications</i>, vol. 17. Springer Nature, 2026.","ama":"Naik S, Keta Y-E, Pranjic-Ferscha K, Hannezo EB, Henkes S, Heisenberg C-PJ. Keratins coordinate tissue spreading by balancing spreading forces with tissue material properties. <i>Nature Communications</i>. 2026;17. doi:<a href=\"https://doi.org/10.1038/s41467-026-72366-z\">10.1038/s41467-026-72366-z</a>"},"title":"Keratins coordinate tissue spreading by balancing spreading forces with tissue material properties","OA_type":"gold","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"Yes","acknowledgement":"We thank all members of the Heisenberg, Henkes, and Hannezo groups for their support. We are also grateful to the Imaging and Optics, Scientific Computing, Life Science Support, and Cryo-Electron Microscopy facilities at ISTA for their technical assistance and support. Numerical simulations were performed using the computational resources from Lorentz Institute and the Academic Leiden Interdisciplinary Cluster Environment (ALICE) provided by Leiden University, and from PMMH provided by Sorbonne Université. S.N has received funding from European Union’s Horizon 2020 research and innovation programme (grant agreement No. 665385). This work was supported by the Austrian Science Fund (FWF) under projects PAT5044023 and W1250 awarded to C.-P.H.","abstract":[{"lang":"eng","text":"For tissues to spread, they must deform while staying intact. How spreading tissues balance flexibility with integrity is not yet well understood. Here, we show that keratin intermediate filaments adapt tissue mechanical resilience to the stresses arising in epithelial tissues during spreading. By analyzing the expansion of the enveloping cell layer (EVL) over the yolk cell in zebrafish embryos in vivo, we find that keratin network maturation in EVL cells is promoted by stresses building up within the spreading tissue. Through genetic interference and tissue rheology experiments, complemented by a vertex model with mechanochemical feedback, we demonstrate that stress-induced keratin network maturation in the EVL increases tissue viscosity, to prevent tissue rupture. Further, keratins are required in the yolk cell for mechanosensitive actomyosin network contraction and flow, the forces pulling the EVL. These dual mechanosensitive functions of keratins enable a balance between pulling force production and EVL mechanical resilience, ensuring uniform and robust tissue spreading."}],"article_type":"original","publisher":"Springer Nature","scopus_import":"1","date_created":"2026-07-29T09:10:35Z","OA_place":"publisher","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"_id":"22608","quality_controlled":"1","ddc":["570"],"acknowledged_ssus":[{"_id":"Bio"},{"_id":"ScienComp"},{"_id":"LifeSc"},{"_id":"EM-Fac"}],"dataavailabilitystatement":"The authors declare that the minimum dataset that is necessary to\r\ninterpret, verify, and extend the research in this article is included in\r\nthe supplementary information, the source data, and the archived data\r\nrepository (https://doi.org/10.15479/AT-ISTA-21137). This is also available\r\non GitHub at https://github.com/Suyash-Naik/2026-\r\nKeratinepithlialspreadingcoordinate-Data. Source data are provided\r\nwith this paper. The framework to develop the vertex models used in this paper are\r\navailable online on GitHub and archived in the source data provided.\r\nCustom scripts used for analysis of imaging and simulation data are\r\nprovided along with data files for all panels in the source data for this\r\nmanuscript on GitHub and in data repo (https://doi.org/10.15479/ATISTA-\r\n21137). Framework for the vertex model is available at https://\r\ngithub.com/yketta/cells. Code for analysis is available on GitHub\r\nhttps://github.com/Suyash-Naik/2026-\r\nKeratinepithlialspreadingcoordinate-Data.","corr_author":"1","oa":1,"status":"public","publication":"Nature Communications","month":"07","oa_version":"Published Version","doi":"10.1038/s41467-026-72366-z","file":[{"checksum":"f26d96e180c1d034d9c9c8f57c3c258b","file_id":"22609","file_size":15363936,"content_type":"application/pdf","relation":"main_file","access_level":"open_access","creator":"dernst","file_name":"2026_NatureComm_Naik.pdf","date_updated":"2026-07-29T10:27:25Z","date_created":"2026-07-29T10:27:25Z","success":1}],"author":[{"id":"2C0B105C-F248-11E8-B48F-1D18A9856A87","first_name":"Suyash","full_name":"Naik, Suyash","last_name":"Naik","orcid":"0000-0001-8421-5508"},{"last_name":"Keta","full_name":"Keta, Yann-Edwin","first_name":"Yann-Edwin"},{"id":"4362B3C2-F248-11E8-B48F-1D18A9856A87","first_name":"Kornelija","full_name":"Pranjic-Ferscha, Kornelija","last_name":"Pranjic-Ferscha"},{"orcid":"0000-0001-6005-1561","last_name":"Hannezo","full_name":"Hannezo, Edouard B","first_name":"Edouard B","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Silke","full_name":"Henkes, Silke","last_name":"Henkes"},{"full_name":"Heisenberg, Carl-Philipp J","last_name":"Heisenberg","orcid":"0000-0002-0912-4566","id":"39427864-F248-11E8-B48F-1D18A9856A87","first_name":"Carl-Philipp J"}],"researchdata_availability":"yes","pmid":1,"related_material":{"record":[{"id":"20465","status":"public","relation":"earlier_version"}]},"external_id":{"pmid":["42143048"]},"das_tickbox":"1","intvolume":"        17","publication_status":"published","article_number":"6499","PlanS_conform":"1"},{"pmid":1,"external_id":{"pmid":["42532904"]},"oa_version":"Published Version","researchdata_availability":"no","author":[{"id":"BB243B88-D767-11E9-B658-BC13E6697425","first_name":"Seungho","full_name":"Lee, Seungho","last_name":"Lee","orcid":"0000-0002-6962-8598"},{"first_name":"Daniel","id":"302BADF6-85FC-11EA-9E3B-B9493DDC885E","orcid":"0000-0001-7597-043X","last_name":"Balazs","full_name":"Balazs, Daniel"},{"full_name":"Rayaroth Puthiyaveettil, Aiswarya","last_name":"Rayaroth Puthiyaveettil","id":"8aceb01b-8972-11ed-ae7b-d5fe53775add","first_name":"Aiswarya"},{"first_name":"Sharona","id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc","last_name":"Horta","full_name":"Horta, Sharona"},{"last_name":"Goodrich","orcid":"0000-0002-1307-5074","full_name":"Goodrich, Carl Peter","first_name":"Carl Peter","id":"EB352CD2-F68A-11E9-89C5-A432E6697425"},{"first_name":"Michael","last_name":"Engel","full_name":"Engel, Michael"},{"full_name":"Cherniukh, Ihor","last_name":"Cherniukh","id":"d03b62b2-5976-11ef-a8d7-9525504b7895","first_name":"Ihor"},{"id":"43C61214-F248-11E8-B48F-1D18A9856A87","first_name":"Maria","full_name":"Ibáñez, Maria","orcid":"0000-0001-5013-2843","last_name":"Ibáñez"}],"file":[{"checksum":"063314ae5ac4225ebd4436aa8707d113","access_level":"open_access","relation":"main_file","file_id":"22646","file_size":6564594,"content_type":"application/pdf","success":1,"date_created":"2026-08-04T06:40:17Z","date_updated":"2026-08-04T06:40:17Z","file_name":"2026_JACS_Lee.pdf","creator":"dernst"}],"doi":"10.1021/jacs.6c07859","intvolume":"       148","das_tickbox":"0","PlanS_conform":"1","issue":"29","publication_status":"published","title":"Reaction medium asan architect of nanocrystal superlattices","citation":{"apa":"Lee, S., Balazs, D., Rayaroth Puthiyaveettil, A., Horta, S., Goodrich, C. P., Engel, M., … Ibáñez, M. (2026). Reaction medium asan architect of nanocrystal superlattices. <i>Journal of the AmericanChemical Society</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/jacs.6c07859\">https://doi.org/10.1021/jacs.6c07859</a>","ieee":"S. Lee <i>et al.</i>, “Reaction medium asan architect of nanocrystal superlattices,” <i>Journal of the AmericanChemical Society</i>, vol. 148, no. 29. American Chemical Society, pp. 31245–31252, 2026.","ama":"Lee S, Balazs D, Rayaroth Puthiyaveettil A, et al. Reaction medium asan architect of nanocrystal superlattices. <i>Journal of the AmericanChemical Society</i>. 2026;148(29):31245-31252. doi:<a href=\"https://doi.org/10.1021/jacs.6c07859\">10.1021/jacs.6c07859</a>","chicago":"Lee, Seungho, Daniel Balazs, Aiswarya Rayaroth Puthiyaveettil, Sharona Horta, Carl Peter Goodrich, Michael Engel, Ihor Cherniukh, and Maria Ibáñez. “Reaction Medium Asan Architect of Nanocrystal Superlattices.” <i>Journal of the AmericanChemical Society</i>. American Chemical Society, 2026. <a href=\"https://doi.org/10.1021/jacs.6c07859\">https://doi.org/10.1021/jacs.6c07859</a>.","mla":"Lee, Seungho, et al. “Reaction Medium Asan Architect of Nanocrystal Superlattices.” <i>Journal of the AmericanChemical Society</i>, vol. 148, no. 29, American Chemical Society, 2026, pp. 31245–52, doi:<a href=\"https://doi.org/10.1021/jacs.6c07859\">10.1021/jacs.6c07859</a>.","ista":"Lee S, Balazs D, Rayaroth Puthiyaveettil A, Horta S, Goodrich CP, Engel M, Cherniukh I, Ibáñez M. 2026. Reaction medium asan architect of nanocrystal superlattices. Journal of the AmericanChemical Society. 148(29), 31245–31252.","short":"S. Lee, D. Balazs, A. Rayaroth Puthiyaveettil, S. Horta, C.P. Goodrich, M. Engel, I. Cherniukh, M. Ibáñez, Journal of the AmericanChemical Society 148 (2026) 31245–31252."},"supplementarymaterial":"yes","project":[{"_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A","name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery"}],"volume":148,"article_processing_charge":"Yes (via OA deal)","OA_type":"hybrid","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2026-07-15T00:00:00Z","language":[{"iso":"eng"}],"has_accepted_license":"1","department":[{"_id":"MaIb"},{"_id":"LifeSc"},{"_id":"GradSch"},{"_id":"CaGo"}],"file_date_updated":"2026-08-04T06:40:17Z","date_updated":"2026-08-04T06:47:13Z","day":"15","year":"2026","type":"journal_article","publication_identifier":{"issn":["0002-7863"],"eissn":["1520-5126"]},"acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"NMR"},{"_id":"LifeSc"}],"ddc":["540"],"quality_controlled":"1","month":"07","publication":"Journal of the AmericanChemical Society","status":"public","oa":1,"corr_author":"1","publisher":"American Chemical Society","acknowledgement":"ISTA and the Werner Siemens Foundation financially supported this work. The Scientific Service Units (SSU) of ISTA supported this research through resources provided by the Electron Microscopy Facility (EMF), NMR Facility, and the Lab Support Facility (LSF). M.E. acknowledges financial support from Deutsche Forschungsgemeinschaft through Collaborative Research Centre 1411. We thank Dr. Tommaso Constanzo and Tobias Kleinhanns for assistance with high-quality electron microscope image acquisition, Dr. Jeonghyun Park for providing NCs, Dr. Mariano Calcabrini for assistance with the NMR study, and Prof. Jonathan De Roo for fruitful discussions. This work benefited from the use of the SasView application, originally developed under NSF award DMR-0520547. SasView contains code developed with funding from the European Union’s Horizon 2020 research and innovation program under the SINE2020 project, grant agreement No. 654000.","abstract":[{"lang":"eng","text":"Nanocrystal superlattices are commonly formed by changing concentration, solvent conditions, or particle surface chemistry. Although effective, these approaches alter multiple contributions to the interparticle potential simultaneously, making it difficult to isolate the interactions responsible for ordering or to control assembly in chemically complex environments. Here, we show that oligomeric species present in a nanocrystal reaction medium drive superlattice formation through a depletion mechanism. Using PbTe nanocrystals as a model system, we identify Pb–oleate oligomers in the crude reaction mixture, characterize their solution structure, and quantify their contribution to the interparticle potential, establishing depletion as the dominant short-range interaction governing spontaneous body-centered cubic superlattice formation. We then confirm the depletion origin of ordering by showing that varying depletant concentration predictably shifts the order–disorder boundary and produces a thermally reversible transition between dispersed and ordered states ─ behavior that is inconsistent with van der Waals or ligand-mediated mechanisms but is a direct consequence of depletion control. Having established and validated the mechanism, we demonstrate that the same depletion framework can be deliberately activated in purified dispersions and transferred across nanocrystal systems of different composition and shape, including anisotropic and binary assemblies. These results establish precursor-derived depletion as a general and chemically grounded mechanism for nanocrystal superlattice formation, and show that collective ordering can be programmed through the surrounding medium rather than through particle surface modification."}],"article_type":"original","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"_id":"22645","OA_place":"publisher","scopus_import":"1","date_created":"2026-08-04T06:29:31Z","page":"31245-31252"},{"year":"2026","publication_identifier":{"issn":["1097-2765"],"eissn":["1097-4164"]},"type":"journal_article","date_updated":"2026-08-12T12:08:44Z","day":"22","has_accepted_license":"1","department":[{"_id":"LeSa"}],"date_published":"2026-06-22T00:00:00Z","language":[{"iso":"eng"}],"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","OA_type":"hybrid","main_file_link":[{"url":"https://doi.org/10.1016/j.molcel.2026.05.026","open_access":"1"}],"article_processing_charge":"Yes (via OA deal)","title":"Structure of E. Coli twin-arginine translocase (Tat) complex with bound cargo","supplementarymaterial":"yes","citation":{"ista":"Zhao Z, Sazanov LA. Structure of E. Coli twin-arginine translocase (Tat) complex with bound cargo. Molecular Cell.","mla":"Zhao, Ziyu, and Leonid A. Sazanov. “Structure of E. Coli Twin-Arginine Translocase (Tat) Complex with Bound Cargo.” <i>Molecular Cell</i>, Elsevier, doi:<a href=\"https://doi.org/10.1016/j.molcel.2026.05.026\">10.1016/j.molcel.2026.05.026</a>.","short":"Z. Zhao, L.A. Sazanov, Molecular Cell (n.d.).","ama":"Zhao Z, Sazanov LA. Structure of E. Coli twin-arginine translocase (Tat) complex with bound cargo. <i>Molecular Cell</i>. doi:<a href=\"https://doi.org/10.1016/j.molcel.2026.05.026\">10.1016/j.molcel.2026.05.026</a>","apa":"Zhao, Z., &#38; Sazanov, L. A. (n.d.). Structure of E. Coli twin-arginine translocase (Tat) complex with bound cargo. <i>Molecular Cell</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.molcel.2026.05.026\">https://doi.org/10.1016/j.molcel.2026.05.026</a>","ieee":"Z. Zhao and L. A. Sazanov, “Structure of E. Coli twin-arginine translocase (Tat) complex with bound cargo,” <i>Molecular Cell</i>. Elsevier.","chicago":"Zhao, Ziyu, and Leonid A Sazanov. “Structure of E. Coli Twin-Arginine Translocase (Tat) Complex with Bound Cargo.” <i>Molecular Cell</i>. Elsevier, n.d. <a href=\"https://doi.org/10.1016/j.molcel.2026.05.026\">https://doi.org/10.1016/j.molcel.2026.05.026</a>."},"OA_place":"publisher","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","short":"CC BY-NC (4.0)","image":"/images/cc_by_nc.png"},"_id":"22148","scopus_import":"1","date_created":"2026-06-28T22:01:35Z","acknowledgement":"We thank IST Austria for providing the funding. We thank IST Austria EM facility for the use of Titan Krios TEM. Data processing was performed using IST high-performance computer cluster. We thank Dr. R. Roemhild and Professor C. Guet (ISTA) for help in constructing Tat deletion strains and Dr. A. Charnagalov (ISTA) for technical help.","abstract":[{"lang":"eng","text":"How the twin-arginine translocase (Tat) system transports fully folded substrate proteins across cellular membranes without disrupting membrane integrity has been a fundamental question in cell biology for decades. The Tat system, found in prokaryotes and plant organelles, recognizes a cargo signal peptide via a conserved twin-arginine motif. The multi-subunit Tat complex facilitates the proton-motive-force-dependent translocation process, yet its overall architecture has remained unknown. Here, we present the cryo-electron microscopy (cryo-EM) structure of the Escherichia coli (E. coli) trimeric TatB₃C₃ complex with bound substrate SufI, assembled in vivo. The complex adopts an unusual, wide-open, bowl-shaped architecture with a polar inner cavity. Unexpectedly, the cargo is engaged in a dual-contact mode: while the signal peptide binds inside one TatBC unit, the folded domain docks tightly onto an adjacent unit, possibly performing a proofreading function. This structure provides a mechanistic framework for substrate engagement and suggests the direct involvement of the entire Tat complex in substrate translocation."}],"article_type":"original","publisher":"Elsevier","corr_author":"1","license":"https://creativecommons.org/licenses/by-nc/4.0/","month":"06","publication":"Molecular Cell","oa":1,"status":"public","quality_controlled":"1","ddc":["570"],"acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"ScienComp"}],"dataavailabilitystatement":"This study did not generate new unique reagents. Strains and plasmids generated in this study are available from the lead contact without restrictions.\r\n• Source data are provided within this paper. The cryo-EM map is deposited in the Electron Microscopy Data Bank under accession number EMD-53848. The model is deposited in the Protein Data Bank under accession number 9R91. The structural data are publicly available as of the date of publication. Raw images of spot assays, SDS-PAGE and BN-PAGE gels with Coomassie staining and immunoblot images are available at Mendeley Data (https://doi.org/10.17632/v2g3p9n985.1).\r\n• This paper does not report original code.\r\n• Any additional information required to reanalyze the data reported in this paper is available from the lead contact upon request.","doi":"10.1016/j.molcel.2026.05.026","researchdata_availability":"yes","author":[{"id":"a63fe682-9f3a-11ee-bf8c-cfdf919b9850","first_name":"Ziyu","full_name":"Zhao, Ziyu","last_name":"Zhao"},{"orcid":"0000-0002-0977-7989","last_name":"Sazanov","full_name":"Sazanov, Leonid A","first_name":"Leonid A","id":"338D39FE-F248-11E8-B48F-1D18A9856A87"}],"oa_version":"Published Version","external_id":{"biorxivid":["10.1101/2025.09.16.676506"]},"biorxivid":1,"related_material":{"link":[{"url":"https://ista.ac.at/en/news/the-gate-for-bulky-cargo/","relation":"press_release","description":"News on ISTA website"}],"record":[{"id":"22189","status":"public","relation":"research_data"}]},"publication_status":"inpress","das_tickbox":"1"},{"OA_type":"hybrid","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"Yes (via OA deal)","project":[{"_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A","name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery"}],"volume":11,"title":"Exploiting mismatch strain and the β–α phase transition for microstructural engineering in thermoelectric Ag2Se","citation":{"ama":"Liu Y, Kleinhanns T, Spadaro MC, et al. Exploiting mismatch strain and the β–α phase transition for microstructural engineering in thermoelectric Ag2Se. <i>ACS Energy Letters</i>. 2026;11(8):5752-5762. doi:<a href=\"https://doi.org/10.1021/acsenergylett.6c01499\">10.1021/acsenergylett.6c01499</a>","apa":"Liu, Y., Kleinhanns, T., Spadaro, M. C., Genç, A., Horta, S., Jakhar, N., … Ibáñez, M. (2026). Exploiting mismatch strain and the β–α phase transition for microstructural engineering in thermoelectric Ag2Se. <i>ACS Energy Letters</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsenergylett.6c01499\">https://doi.org/10.1021/acsenergylett.6c01499</a>","chicago":"Liu, Yu, Tobias Kleinhanns, Maria Chiara Spadaro, Aziz Genç, Sharona Horta, Navita Jakhar, Tommaso Costanzo, et al. “Exploiting Mismatch Strain and the β–α Phase Transition for Microstructural Engineering in Thermoelectric Ag2Se.” <i>ACS Energy Letters</i>. American Chemical Society, 2026. <a href=\"https://doi.org/10.1021/acsenergylett.6c01499\">https://doi.org/10.1021/acsenergylett.6c01499</a>.","ieee":"Y. Liu <i>et al.</i>, “Exploiting mismatch strain and the β–α phase transition for microstructural engineering in thermoelectric Ag2Se,” <i>ACS Energy Letters</i>, vol. 11, no. 8. American Chemical Society, pp. 5752–5762, 2026.","mla":"Liu, Yu, et al. “Exploiting Mismatch Strain and the β–α Phase Transition for Microstructural Engineering in Thermoelectric Ag2Se.” <i>ACS Energy Letters</i>, vol. 11, no. 8, American Chemical Society, 2026, pp. 5752–62, doi:<a href=\"https://doi.org/10.1021/acsenergylett.6c01499\">10.1021/acsenergylett.6c01499</a>.","ista":"Liu Y, Kleinhanns T, Spadaro MC, Genç A, Horta S, Jakhar N, Costanzo T, Dutkiewicz E, Arbiol J, Hong M, Ibáñez M. 2026. Exploiting mismatch strain and the β–α phase transition for microstructural engineering in thermoelectric Ag2Se. ACS Energy Letters. 11(8), 5752–5762.","short":"Y. Liu, T. Kleinhanns, M.C. Spadaro, A. Genç, S. Horta, N. Jakhar, T. Costanzo, E. Dutkiewicz, J. Arbiol, M. Hong, M. Ibáñez, ACS Energy Letters 11 (2026) 5752–5762."},"supplementarymaterial":"yes","type":"journal_article","publication_identifier":{"eissn":["2380-8195"]},"year":"2026","file_date_updated":"2026-08-19T05:52:41Z","day":"14","date_updated":"2026-08-19T05:53:33Z","has_accepted_license":"1","department":[{"_id":"MassSpec"},{"_id":"MaIb"},{"_id":"GradSch"},{"_id":"EM-Fac"}],"date_published":"2026-08-14T00:00:00Z","language":[{"iso":"eng"}],"corr_author":"1","publication":"ACS Energy Letters","month":"08","status":"public","oa":1,"ddc":["540"],"quality_controlled":"1","acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"LifeSc"},{"_id":"NanoFab"},{"_id":"MassSpec"}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"_id":"22734","OA_place":"publisher","page":"5752-5762","date_created":"2026-08-18T11:34:03Z","scopus_import":"1","abstract":[{"text":"Silver selenide (Ag2Se) is a promising near-room-temperature thermoelectric material, but its narrow stoichiometric window and β–α phase transition complicate reproducible microstructure control. Here, we present a mismatch-assisted microstructure engineering strategy in which Ag2Se particles are treated with polyanionic ZnSe complexes and consolidated through the β–α transition to introduce ZnSe nanoprecipitates, Ag2Se/ZnSe interfaces, and local strain fields. The crystallographic mismatch between ZnSe and Ag2Se, together with the Zn2+/Ag+ size difference, amplifies phase-transition-induced deformation and promotes high-density dislocations with periodic strain modulations. This defect architecture suppresses grain coarsening, removes excess Ag, limits Ag-interstitial formation, and reduces lattice thermal conductivity through lattice softening and multiscale phonon scattering. Ag2Se–4%ZnSe nanocomposites achieve a peak zTmax of 1.13 at 369 K and a zTavg of 1.08 from 300 to 380 K, demonstrating mismatch-driven defect engineering through the β–α phase transition as a route for optimizing Ag2Se-based thermoelectrics.","lang":"eng"}],"acknowledgement":"Open access funding provided by Institute of Science and Technology Austria. M.I. acknowledges financial support from ISTA and the Werner Siemens Foundation. The Scientific Service Units (SSU) of ISTA supported this work through resources provided by the Electron Microscopy Facility (EMF), the Lab Support Facility (LSF), the Nanofabrication Facility (NNF), and the Mass Spectrometry Facility. Y.L. acknowledges funding from the National Natural Science Foundation of China (NSFC) (grant no. 22209034) and the Fundamental Research Funds for the Central Universities (JZ2024HGTB0239). M.H. acknowledges funding from Australian Research Council (FT230100316), and the high-performance computing resources provided by National Computational Infrastructure (it39) and Pawsey Supercomputing Centre (pawsey1075). ICN2 acknowledges funding from Generalitat de Catalunya 2021SGR00457. The authors thank support from the project AMaDE (PID2023-149158OB-C43), funded by MCIN/AEI/10.13039/501100011033/ and by the “ERDF Away of making Europe”, by the “European Union”. ICN2 is supported by the Severo Ochoa program from Spanish MCIN/AEI (grant no.: CEX2021-001214-S) and is funded by the CERCA Programme/Generalitat de Catalunya. Authors acknowledge the use of instrumentation as well as the technical advice provided by the Joint Electron Microscopy Center at ALBA (JEMCA). ICN2 acknowledges funding from Grant IU16-014206 (METCAM-FIB) funded by the European Union through the European Regional Development Fund (ERDF), with the support of the Ministry of Research and Universities, Generalitat de Catalunya. ICN2 is founding member of e-DREAM. (91)","article_type":"letter_note","publisher":"American Chemical Society","doi":"10.1021/acsenergylett.6c01499","researchdata_availability":"no","file":[{"success":1,"date_created":"2026-08-19T05:52:41Z","date_updated":"2026-08-19T05:52:41Z","file_name":"2026_ACSEnergyLetters_Liu.pdf","creator":"dernst","checksum":"4d75c5a79d112c845c9eecba8838db38","file_id":"22736","content_type":"application/pdf","file_size":6806815,"access_level":"open_access","relation":"main_file"}],"author":[{"id":"2A70014E-F248-11E8-B48F-1D18A9856A87","first_name":"Yu","full_name":"Liu, Yu","orcid":"0000-0001-7313-6740","last_name":"Liu"},{"full_name":"Kleinhanns, Tobias","last_name":"Kleinhanns","orcid":"0000-0003-1537-7436","id":"8BD9DE16-AB3C-11E9-9C8C-2A03E6697425","first_name":"Tobias"},{"first_name":"Maria Chiara","full_name":"Spadaro, Maria Chiara","last_name":"Spadaro"},{"full_name":"Genç, Aziz","last_name":"Genç","first_name":"Aziz"},{"first_name":"Sharona","id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc","last_name":"Horta","full_name":"Horta, Sharona"},{"full_name":"Navita, Navita","last_name":"Navita","orcid":"0000-0001-7408-8197","id":"6ebe278d-ba0b-11ee-8184-f34cdc671de4","first_name":"Navita"},{"full_name":"Costanzo, Tommaso","orcid":"0000-0001-9732-3815","last_name":"Costanzo","id":"D93824F4-D9BA-11E9-BB12-F207E6697425","first_name":"Tommaso"},{"full_name":"Dutkiewicz, Ewelina","last_name":"Dutkiewicz","id":"0601cc46-c082-11ec-9b07-bb29641d1de9","first_name":"Ewelina"},{"first_name":"Jordi","last_name":"Arbiol","full_name":"Arbiol, Jordi"},{"full_name":"Hong, Min","last_name":"Hong","first_name":"Min"},{"first_name":"Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5013-2843","last_name":"Ibáñez","full_name":"Ibáñez, Maria"}],"oa_version":"Published Version","issue":"8","publication_status":"published","PlanS_conform":"1","intvolume":"        11","das_tickbox":"0"},{"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","article_processing_charge":"No","project":[{"call_identifier":"H2020","_id":"0aa60e99-070f-11eb-9043-a6de6bdc3afa","name":"Tribocharge: a multi-scale approach to an enduring problem in physics","grant_number":"949120"}],"title":"Experimental probing of nanoscale charge features and surface morphology changes during tribocharging","citation":{"short":"F. Pertl, Experimental Probing of Nanoscale Charge Features and Surface Morphology Changes during Tribocharging, Institute of Science and Technology Austria, 2026.","mla":"Pertl, Felix. <i>Experimental Probing of Nanoscale Charge Features and Surface Morphology Changes during Tribocharging</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22684\">10.15479/AT-ISTA-22684</a>.","ista":"Pertl F. 2026. Experimental probing of nanoscale charge features and surface morphology changes during tribocharging. Institute of Science and Technology Austria.","apa":"Pertl, F. (2026). <i>Experimental probing of nanoscale charge features and surface morphology changes during tribocharging</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-22684\">https://doi.org/10.15479/AT-ISTA-22684</a>","ama":"Pertl F. Experimental probing of nanoscale charge features and surface morphology changes during tribocharging. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22684\">10.15479/AT-ISTA-22684</a>","chicago":"Pertl, Felix. “Experimental Probing of Nanoscale Charge Features and Surface Morphology Changes during Tribocharging.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-22684\">https://doi.org/10.15479/AT-ISTA-22684</a>.","ieee":"F. Pertl, “Experimental probing of nanoscale charge features and surface morphology changes during tribocharging,” Institute of Science and Technology Austria, 2026."},"type":"dissertation","publication_identifier":{"isbn":["978-3-99078-083-1"],"issn":["2663-337X"]},"year":"2026","file_date_updated":"2026-08-12T13:04:21Z","day":"12","date_updated":"2026-08-27T11:42:44Z","department":[{"_id":"GradSch"},{"_id":"ScWa"}],"has_accepted_license":"1","language":[{"iso":"eng"}],"date_published":"2026-08-12T00:00:00Z","corr_author":"1","month":"08","status":"public","oa":1,"ddc":["530"],"acknowledged_ssus":[{"_id":"NanoFab"},{"_id":"ScienComp"},{"_id":"LifeSc"},{"_id":"M-Shop"},{"_id":"EM-Fac"}],"degree_awarded":"PhD","_id":"22684","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"OA_place":"publisher","page":"107","date_created":"2026-08-12T09:44:40Z","ec_funded":1,"acknowledgement":"This project has received financing from the European Research Council grant agreement\r\nno. 949120 under the European Union’s Horizon 2020 research and innovation programme.\r\nThis research was supported by the Scientific Service Units of The Institute of Science\r\nand Technology Austria (ISTA) through resources provided by the Miba Machine Shop, the\r\nNanofabrication Facility, the Lab Support Facility, the Scientific Computing Facility and the\r\nElectron Microscopy Facility. We thank Florian Stumpf from Park Systems for useful discussions\r\nand support with scanning probe microscopy. We thank Joaquin Garcia-Suarez and Guillaume\r\nAnciaux for the suggestion to look into the roughness power spectral density. We thank\r\nIrina-Malina Strugaru for help with testing the device for Young’s modulus measurements.\r\n","abstract":[{"text":"Contact electrification (CE) is a simple yet elusive phenomenon that occurs when two materials come into contact and separate, leaving behind net electrical charge. Despite its ubiquity, the microscopic origin of CE remains unclear. In this thesis, we investigate CE from three complementary perspectives: developing a quantitative method to measure charge at the nanoscale, exploring the dynamic behavior of charge on insulating surfaces, and uncovering the role of mechanical history in forming a triboelectric series.\r\n\r\nIn the first part, we establish a rigorous framework for converting qualitative Kelvin probe force microscopy (KPFM) voltage maps into quantitative charge density distributions. Using finite element method (FEM) simulations, we determine the point-spread function of the KPFM tip–sample geometry and demonstrate that the true surface charge can be reconstructed by numerical deconvolution. This procedure enables the recovery of both the magnitude and sign of charge density with high fidelity, resolving nanoscale features that are otherwise obscured. Applying the method to contact-charged SiO$_2$ surfaces, we show that existing analytical approximations, such as parallel plate or spherical models, can miscalculate charge magnitude by orders of magnitude. Our hybrid FEM/KPFM approach therefore provides a fast and general method to convert qualitative KPFM signals into quantitative charge data, enabling nanoscale charge mapping under realistic experimental conditions.\r\n\r\nIn the second part, we study the temporal stability of CE-induced charges and identify the key material factors that determine whether KPFM can capture meaningful charge patterns. Through time-resolved experiments combining a custom-built transfer system with both microscopic and macroscopic measurements, we demonstrate that only the best insulators, such as SiO$_2$, preserve CE charge long enough for stationary imaging. For less conductive polymers, such as PDMS, charge decays within the duration of a single KPFM scan due to bulk conduction. Using a simple capacitor-based model, we reproduce the observed decay dynamics and confirm that the transferred charge decays characteristic to the sample's bulk conductivity. Further, we always observe homogeneous charge transfer.\r\n\r\nIn the third part, we address the question: can we form a triboelectric series with identical materials? Using controlled repetitive contact experiments, we show that nominally identical materials can progressively order themselves into a triboelectric series, where surfaces with more contact history charge negatively relative to fresher ones. By constructing a minimal model based on this ``contact bias'', we replicate the evolution from random to ordered charging observed in experiments. Supporting surface analyses, including atomic force microscopy, reveal that repeated contact induces nanoscale morphological changes, suggesting a mechanism tightly coupled to mechanical strain. These results highlight the crucial role of surface history and nanoscale mechanics in dictating charge transfer, motivating further exploration of mechanisms such as mechanochemical bond cleavage and flexoelectric polarization.","lang":"eng"}],"publisher":"Institute of Science and Technology Austria","supervisor":[{"id":"3A1FFC16-F248-11E8-B48F-1D18A9856A87","first_name":"Scott R","full_name":"Waitukaitis, Scott R","last_name":"Waitukaitis","orcid":"0000-0002-2299-3176"}],"doi_confirm":"1","related_material":{"record":[{"id":"20481","relation":"part_of_dissertation","status":"public"},{"status":"public","relation":"part_of_dissertation","id":"12109"},{"relation":"part_of_dissertation","status":"public","id":"19278"},{"id":"17373","relation":"part_of_dissertation","status":"public"}]},"doi":"10.15479/AT-ISTA-22684","author":[{"full_name":"Pertl, Felix","orcid":"0000-0003-0463-5794","last_name":"Pertl","id":"6313aec0-15b2-11ec-abd3-ed67d16139af","first_name":"Felix"}],"file":[{"file_name":"2026_Pertl_Felix_Thesis.zip","creator":"fpertl","date_updated":"2026-08-12T13:04:21Z","date_created":"2026-08-12T13:04:21Z","checksum":"0a4f5a941c40b921447e72291d72bc6f","file_id":"22690","content_type":"application/x-zip-compressed","file_size":31192621,"relation":"source_file","access_level":"closed"},{"date_created":"2026-08-12T13:04:21Z","date_updated":"2026-08-12T13:04:21Z","creator":"fpertl","file_name":"2026_Pertl_Felix_Thesis.pdf","file_id":"22691","file_size":27882509,"content_type":"application/pdf","relation":"main_file","access_level":"open_access","checksum":"ae60dcdb363222138886b2857643d4e3"}],"oa_version":"Published Version","alternative_title":["ISTA Thesis"],"publication_status":"published"},{"article_processing_charge":"No","OA_type":"closed access","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"ista":"Springstein BL, Javoor M, Megrian D, Hajdu R, Hanke DM, Zens B, Weiss GL, Schur FK, Loose M. 2026. Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape. Science. 392(6795), eaea6343.","mla":"Springstein, Benjamin L., et al. “Repurposing of a DNA Segregation Machinery into a Cytoskeletal System Controlling Cell Shape.” <i>Science</i>, vol. 392, no. 6795, eaea6343, AAAS, 2026, doi:<a href=\"https://doi.org/10.1126/science.aea6343\">10.1126/science.aea6343</a>.","short":"B.L. Springstein, M. Javoor, D. Megrian, R. Hajdu, D.M. Hanke, B. Zens, G.L. Weiss, F.K. Schur, M. Loose, Science 392 (2026).","ieee":"B. L. Springstein <i>et al.</i>, “Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape,” <i>Science</i>, vol. 392, no. 6795. AAAS, 2026.","ama":"Springstein BL, Javoor M, Megrian D, et al. Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape. <i>Science</i>. 2026;392(6795). doi:<a href=\"https://doi.org/10.1126/science.aea6343\">10.1126/science.aea6343</a>","apa":"Springstein, B. L., Javoor, M., Megrian, D., Hajdu, R., Hanke, D. M., Zens, B., … Loose, M. (2026). Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape. <i>Science</i>. AAAS. <a href=\"https://doi.org/10.1126/science.aea6343\">https://doi.org/10.1126/science.aea6343</a>","chicago":"Springstein, Benjamin L, Manjunath Javoor, Daniela Megrian, Roman Hajdu, Dustin M. Hanke, Bettina Zens, Gregor L. Weiss, Florian KM Schur, and Martin Loose. “Repurposing of a DNA Segregation Machinery into a Cytoskeletal System Controlling Cell Shape.” <i>Science</i>. AAAS, 2026. <a href=\"https://doi.org/10.1126/science.aea6343\">https://doi.org/10.1126/science.aea6343</a>."},"title":"Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape","volume":392,"project":[{"name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413","call_identifier":"H2020","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"},{"grant_number":"101076260","name":"A molecular atlas of Actin filament IDentities in the cell motility machinery","_id":"bd980d18-d553-11ed-ba76-ceaa645c97eb"}],"date_updated":"2026-09-03T09:36:24Z","day":"16","publication_identifier":{"issn":["0036-8075"],"eissn":["1095-9203"]},"year":"2026","type":"journal_article","language":[{"iso":"eng"}],"date_published":"2026-04-16T00:00:00Z","department":[{"_id":"MaLo"},{"_id":"FlSc"},{"_id":"GradSch"},{"_id":"EM-Fac"}],"status":"public","month":"04","publication":"Science","corr_author":"1","acknowledged_ssus":[{"_id":"Bio"},{"_id":"ScienComp"},{"_id":"EM-Fac"},{"_id":"LifeSc"}],"quality_controlled":"1","scopus_import":"1","date_created":"2026-04-26T22:01:46Z","_id":"21762","publisher":"AAAS","acknowledgement":"We thank all members of the Loose lab at ISTA for helpful discussions; M. Kojic for critical reading of the manuscript; A. Herrero (Sevilla University) for sharing her extensive BACTH plasmid library and other plasmids, as well as cyanobacterial strains; T. Dagan and F. Nies (both Kiel University) for sharing cyanobacterial strains and plasmids and for valuable discussions; N. Sapay and A. Michon for providing the Amphipaseek code, which enabled us to perform our large-scale amphipathic helix screen of cyanobacterial CorR proteins; V.-V. Hodirnau for support in cryo-ET data collection; and J. Hansen for advice about cryo-EM data processing.\r\nThis work was supported by the Scientific Service Units (SSU) of ISTA through resources provided by the Imaging & Optics Facility (IOF), the Scientific Computing (SciComp), the Electron Microscopy Facility (EMF), and the Lab Support Facility (LSF). This work was funded by the European Union’s Horizon 2020 research and innovation program (Marie Skłodowska-Curie grant 101034413 to B.L.S.); the European Research Council (ERC) of the European Union (grant ActinID 101076260 to F.K.M.S.); the Swiss National Science Foundation (starting grant TMSGI3_226208 to G.L.W.); and the Jean-Jacques et Letitia Lopez-Loreta Foundation (G.L.W.).","article_type":"original","abstract":[{"lang":"eng","text":"Bacteria, like eukaryotes, use conserved cytoskeletal systems for intracellular organization. The plasmid-encoded ParMRC system forms actin-like filaments that segregate low–copy number plasmids. In multicellular cyanobacteria such as Anabaena sp., we found that a chromosomally encoded ParMR system has evolved into a cytoskeletal system named CorMR with a function in cell shape control rather than DNA segregation. Live-cell imaging, in vitro reconstitution, and cryo–electron microscopy revealed that CorM formed dynamically unstable, antiparallel double-stranded filaments that were recruited to the membrane by CorR through an amphipathic helix conserved in multicellular cyanobacteria. CorMR filaments were regulated by MinC, which excluded them from the poles and division plane. Comparative genomics indicated that the repurposing of ParMR and Min systems coevolved with cyanobacterial multicellularity, highlighting the evolutionary plasticity of cytoskeletal systems in bacteria."}],"ec_funded":1,"external_id":{"pmid":["41990175"]},"related_material":{"record":[{"status":"public","relation":"dissertation_contains","id":"22744"}]},"pmid":1,"author":[{"id":"b4eb62ef-ac72-11ed-9503-ed3b4d66c083","first_name":"Benjamin L","full_name":"Springstein, Benjamin L","orcid":"0000-0002-3461-5391","last_name":"Springstein"},{"last_name":"Javoor","orcid":"0000-0003-2311-2112","full_name":"Javoor, Manjunath","first_name":"Manjunath","id":"305ab18b-dc7d-11ea-9b2f-b58195228ea2"},{"full_name":"Megrian, Daniela","last_name":"Megrian","first_name":"Daniela"},{"id":"ffab949d-133f-11ed-8f02-94de21ace503","first_name":"Roman","full_name":"Hajdu, Roman","last_name":"Hajdu"},{"first_name":"Dustin M.","full_name":"Hanke, Dustin M.","last_name":"Hanke"},{"full_name":"Zens, Bettina","orcid":"0000-0002-9561-1239","last_name":"Zens","id":"45FD126C-F248-11E8-B48F-1D18A9856A87","first_name":"Bettina"},{"first_name":"Gregor L.","last_name":"Weiss","full_name":"Weiss, Gregor L."},{"full_name":"Schur, Florian Km","last_name":"Schur","orcid":"0000-0003-4790-8078","id":"48AD8942-F248-11E8-B48F-1D18A9856A87","first_name":"Florian Km"},{"id":"462D4284-F248-11E8-B48F-1D18A9856A87","first_name":"Martin","full_name":"Loose, Martin","last_name":"Loose","orcid":"0000-0001-7309-9724"}],"doi":"10.1126/science.aea6343","oa_version":"None","article_number":"eaea6343","publication_status":"published","issue":"6795","intvolume":"       392"},{"acknowledgement":"This work was supported by the ERC StG grant ActinID (PRA01221F1049A) awarded to Florian\r\nSchur, the ERC-SyG grant Pushing from within (P01071793) awarded to Michael Sixt, and by ISTA.\r\nI would like to thank the Scientific Service Units at ISTA for their essential support throughout\r\nthis work. In particular, I am grateful to the Electron Microscopy Facility, Imaging and Optics\r\nFacility, Zebrafish Facility, Scientific Computing Facility, and Lab Support Facility for their services,\r\nand technical support, all of which were important for the successful completion of this project.","publisher":"Institute of Science and Technology Austria ","supervisor":[{"id":"48AD8942-F248-11E8-B48F-1D18A9856A87","first_name":"Florian KM","full_name":"Schur, Florian KM","last_name":"Schur","orcid":"0000-0003-4790-8078"},{"last_name":"Sixt","orcid":"0000-0002-6620-9179","full_name":"Sixt, Michael K","first_name":"Michael K","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87"}],"degree_awarded":"PhD","keyword":["Actin cytoskeleton","Cell migration","cryo-electron tomography"],"tmp":{"short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"OA_place":"publisher","_id":"22744","page":"121","date_created":"2026-08-21T09:11:04Z","ddc":["570"],"acknowledged_ssus":[{"_id":"Bio"},{"_id":"EM-Fac"},{"_id":"ScienComp"},{"_id":"LifeSc"}],"corr_author":"1","month":"08","status":"public","department":[{"_id":"GradSch"},{"_id":"FlSc"},{"_id":"MiSi"}],"has_accepted_license":"1","language":[{"iso":"eng"}],"date_published":"2026-08-21T00:00:00Z","publication_identifier":{"issn":["2663-337X"],"isbn":["978-3-99078-090-9 "]},"year":"2026","type":"dissertation","file_date_updated":"2026-08-27T12:48:42Z","date_updated":"2026-09-03T09:36:24Z","day":"21","project":[{"_id":"bd980d18-d553-11ed-ba76-ceaa645c97eb","name":"A molecular atlas of Actin filament IDentities in the cell motility machinery","grant_number":"101076260"},{"_id":"bd91e723-d553-11ed-ba76-fe7eeb2185fd","grant_number":"101071793","name":"Pushing from within: Control of cell shape, integrity and motility by cytoskeletal pushing forces"}],"OA_embargo":"12","title":"Large-scale imaging of cellular actin networks at single filament resolution using montage cryo-electron tomography","citation":{"ieee":"M. Javoor, “Large-scale imaging of cellular actin networks at single filament resolution using montage cryo-electron tomography,” Institute of Science and Technology Austria , 2026.","ama":"Javoor M. Large-scale imaging of cellular actin networks at single filament resolution using montage cryo-electron tomography. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22744\">10.15479/AT-ISTA-22744</a>","chicago":"Javoor, Manjunath. “Large-Scale Imaging of Cellular Actin Networks at Single Filament Resolution Using Montage Cryo-Electron Tomography.” Institute of Science and Technology Austria , 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-22744\">https://doi.org/10.15479/AT-ISTA-22744</a>.","apa":"Javoor, M. (2026). <i>Large-scale imaging of cellular actin networks at single filament resolution using montage cryo-electron tomography</i>. Institute of Science and Technology Austria . <a href=\"https://doi.org/10.15479/AT-ISTA-22744\">https://doi.org/10.15479/AT-ISTA-22744</a>","mla":"Javoor, Manjunath. <i>Large-Scale Imaging of Cellular Actin Networks at Single Filament Resolution Using Montage Cryo-Electron Tomography</i>. Institute of Science and Technology Austria , 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22744\">10.15479/AT-ISTA-22744</a>.","ista":"Javoor M. 2026. Large-scale imaging of cellular actin networks at single filament resolution using montage cryo-electron tomography. Institute of Science and Technology Austria .","short":"M. Javoor, Large-Scale Imaging of Cellular Actin Networks at Single Filament Resolution Using Montage Cryo-Electron Tomography, Institute of Science and Technology Austria , 2026."},"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","article_processing_charge":"No","alternative_title":["ISTA Thesis"],"publication_status":"published","oa_version":"None","doi":"10.15479/AT-ISTA-22744","file":[{"date_updated":"2026-08-27T12:48:42Z","date_created":"2026-08-26T12:02:47Z","file_name":"2026_Javoor_Manjunath_Thesis.docx","creator":"mjavoor","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","file_size":27430796,"file_id":"22767","access_level":"closed","relation":"source_file","checksum":"f9c2847df9f1ac5a3d60c06b3b81a450"},{"embargo_to":"open_access","date_created":"2026-08-26T12:02:46Z","date_updated":"2026-08-26T12:02:46Z","creator":"mjavoor","file_name":"2026_Javoor_Manjunath_Thesis.pdf","file_id":"22768","content_type":"application/pdf","file_size":19489230,"access_level":"closed","relation":"main_file","checksum":"8e9b4c0fcafbccf5c3796eacc9134a08","embargo":"2027-08-21"}],"author":[{"first_name":"Manjunath","id":"305ab18b-dc7d-11ea-9b2f-b58195228ea2","orcid":"0000-0003-2311-2112","last_name":"Javoor","full_name":"Javoor, Manjunath"}],"related_material":{"record":[{"id":"12334","relation":"part_of_dissertation","status":"public"},{"status":"public","relation":"part_of_dissertation","id":"21762"},{"id":"19795","status":"public","relation":"part_of_dissertation"},{"id":"12421","status":"public","relation":"part_of_dissertation"}]},"doi_confirm":"1"},{"abstract":[{"text":"Transcription by RNA polymerase II (Pol II) can be repressed by noncoding RNA, including the human RNA Alu. However, the mechanism by which endogenous RNAs repress transcription remains unclear. Here we present cryogenic-electron microscopy structures of Pol II bound to Alu RNA, which reveal that Alu RNA mimics how DNA and RNA bind to Pol II during transcription elongation. Further, we show how distinct domains of the general transcription factor TFIIF control repressive activity. Together, we reveal how a noncoding RNA can regulate mammalian gene expression.","lang":"eng"}],"acknowledgement":"We thank the members of the Bernecky laboratory for helpful discussions and A. Hlavata for providing Pol II for use in the fluorescence anisotropy binding assay. We thank V.-V. Hodirnau for SerialEM data collection and support with EPU data collection. We thank D. Slade (Max Perutz Laboratories and Medical University of Vienna, Vienna, Austria) for the wild-type TFIIF expression plasmid. We thank N. Thompson and R. Burgess (McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, WI, USA) for the 8WG16 hybridoma cell line. We thank C. Plaschka and M. Loose for critical reading of the manuscript. This work was supported by Austrian Science Fund (FWF) grant no. P34185 (DOI 10.55776/P34185) (C.B.). The funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript. This research was further supported by the Scientific Service Units of ISTA through resources provided by the Laboratory Support Facility, Electron Microscopy Facility, Scientific Computing and the Preclinical Facility.","article_type":"original","publisher":"Springer Nature","_id":"18778","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"OA_place":"publisher","page":"607-612","date_created":"2025-01-08T11:20:20Z","scopus_import":"1","ddc":["570"],"quality_controlled":"1","acknowledged_ssus":[{"_id":"LifeSc"},{"_id":"EM-Fac"},{"_id":"ScienComp"},{"_id":"PreCl"}],"corr_author":"1","isi":1,"month":"04","publication":"Nature Structural & Molecular Biology","status":"public","oa":1,"has_accepted_license":"1","department":[{"_id":"CaBe"}],"language":[{"iso":"eng"}],"date_published":"2025-04-01T00:00:00Z","publication_identifier":{"eissn":["1545-9985"],"issn":["1545-9993"]},"year":"2025","type":"journal_article","file_date_updated":"2025-04-16T08:17:27Z","day":"01","date_updated":"2025-11-20T10:28:36Z","project":[{"_id":"c08a6700-5a5b-11eb-8a69-82a722b2bc30","grant_number":"P34185","name":"Regulation of mammalian transcription by noncoding RNA"}],"volume":32,"title":"Mechanism of mammalian transcriptional repression by noncoding RNA","citation":{"mla":"Tluckova, Katarina, et al. “Mechanism of Mammalian Transcriptional Repression by Noncoding RNA.” <i>Nature Structural &#38; Molecular Biology</i>, vol. 32, Springer Nature, 2025, pp. 607–12, doi:<a href=\"https://doi.org/10.1038/s41594-024-01448-7\">10.1038/s41594-024-01448-7</a>.","ista":"Tluckova K, Kaczmarek BM, Testa Salmazo AP, Bernecky C. 2025. Mechanism of mammalian transcriptional repression by noncoding RNA. Nature Structural &#38; Molecular Biology. 32, 607–612.","short":"K. Tluckova, B.M. Kaczmarek, A.P. Testa Salmazo, C. Bernecky, Nature Structural &#38; Molecular Biology 32 (2025) 607–612.","ama":"Tluckova K, Kaczmarek BM, Testa Salmazo AP, Bernecky C. Mechanism of mammalian transcriptional repression by noncoding RNA. <i>Nature Structural &#38; Molecular Biology</i>. 2025;32:607-612. doi:<a href=\"https://doi.org/10.1038/s41594-024-01448-7\">10.1038/s41594-024-01448-7</a>","apa":"Tluckova, K., Kaczmarek, B. M., Testa Salmazo, A. P., &#38; Bernecky, C. (2025). Mechanism of mammalian transcriptional repression by noncoding RNA. <i>Nature Structural &#38; Molecular Biology</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41594-024-01448-7\">https://doi.org/10.1038/s41594-024-01448-7</a>","ieee":"K. Tluckova, B. M. Kaczmarek, A. P. Testa Salmazo, and C. Bernecky, “Mechanism of mammalian transcriptional repression by noncoding RNA,” <i>Nature Structural &#38; Molecular Biology</i>, vol. 32. Springer Nature, pp. 607–612, 2025.","chicago":"Tluckova, Katarina, Beata M Kaczmarek, Anita P Testa Salmazo, and Carrie Bernecky. “Mechanism of Mammalian Transcriptional Repression by Noncoding RNA.” <i>Nature Structural &#38; Molecular Biology</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41594-024-01448-7\">https://doi.org/10.1038/s41594-024-01448-7</a>."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_type":"hybrid","article_processing_charge":"Yes (in subscription journal)","intvolume":"        32","publication_status":"published","oa_version":"Published Version","doi":"10.1038/s41594-024-01448-7","author":[{"first_name":"Katarina","id":"4AC7D980-F248-11E8-B48F-1D18A9856A87","last_name":"Tluckova","full_name":"Tluckova, Katarina"},{"id":"36FA4AFA-F248-11E8-B48F-1D18A9856A87","first_name":"Beata M","full_name":"Kaczmarek, Beata M","last_name":"Kaczmarek"},{"first_name":"Anita P","id":"41F1F098-F248-11E8-B48F-1D18A9856A87","last_name":"Testa Salmazo","full_name":"Testa Salmazo, Anita P"},{"last_name":"Bernecky","orcid":"0000-0003-0893-7036","full_name":"Bernecky, Carrie A","first_name":"Carrie A","id":"2CB9DFE2-F248-11E8-B48F-1D18A9856A87"}],"file":[{"content_type":"application/pdf","file_size":9306639,"file_id":"19573","access_level":"open_access","relation":"main_file","checksum":"2919b30b271f395888e880076a680d73","file_name":"2025_NatureStrucMolBiol_Tluckova.pdf","creator":"dernst","success":1,"date_updated":"2025-04-16T08:17:27Z","date_created":"2025-04-16T08:17:27Z"}],"APC_amount":"12348 EUR","pmid":1,"related_material":{"record":[{"id":"14644","status":"public","relation":"earlier_version"}]},"external_id":{"isi":["001390268000001"],"pmid":["39762629"]}},{"volume":18,"citation":{"ieee":"G. Zeng <i>et al.</i>, “Modulating the solvation structure to enhance amorphous solid electrolyte interface formation for ultra-stable aqueous zinc anode,” <i>Energy and Environmental Science</i>, vol. 18, no. 4. Royal Society of Chemistry, pp. 1683–1695, 2025.","ama":"Zeng G, Sun Q, Horta S, et al. Modulating the solvation structure to enhance amorphous solid electrolyte interface formation for ultra-stable aqueous zinc anode. <i>Energy and Environmental Science</i>. 2025;18(4):1683-1695. doi:<a href=\"https://doi.org/10.1039/d4ee03750b\">10.1039/d4ee03750b</a>","chicago":"Zeng, Guifang, Qing Sun, Sharona Horta, Paulina R. Martínez-Alanis, Peng Wu, Jing Li, Shang Wang, et al. “Modulating the Solvation Structure to Enhance Amorphous Solid Electrolyte Interface Formation for Ultra-Stable Aqueous Zinc Anode.” <i>Energy and Environmental Science</i>. Royal Society of Chemistry, 2025. <a href=\"https://doi.org/10.1039/d4ee03750b\">https://doi.org/10.1039/d4ee03750b</a>.","apa":"Zeng, G., Sun, Q., Horta, S., Martínez-Alanis, P. R., Wu, P., Li, J., … Cabot, A. (2025). Modulating the solvation structure to enhance amorphous solid electrolyte interface formation for ultra-stable aqueous zinc anode. <i>Energy and Environmental Science</i>. Royal Society of Chemistry. <a href=\"https://doi.org/10.1039/d4ee03750b\">https://doi.org/10.1039/d4ee03750b</a>","short":"G. Zeng, Q. Sun, S. Horta, P.R. Martínez-Alanis, P. Wu, J. Li, S. Wang, M. Ibáñez, Y. Tian, L. Ci, A. Cabot, Energy and Environmental Science 18 (2025) 1683–1695.","mla":"Zeng, Guifang, et al. “Modulating the Solvation Structure to Enhance Amorphous Solid Electrolyte Interface Formation for Ultra-Stable Aqueous Zinc Anode.” <i>Energy and Environmental Science</i>, vol. 18, no. 4, Royal Society of Chemistry, 2025, pp. 1683–95, doi:<a href=\"https://doi.org/10.1039/d4ee03750b\">10.1039/d4ee03750b</a>.","ista":"Zeng G, Sun Q, Horta S, Martínez-Alanis PR, Wu P, Li J, Wang S, Ibáñez M, Tian Y, Ci L, Cabot A. 2025. Modulating the solvation structure to enhance amorphous solid electrolyte interface formation for ultra-stable aqueous zinc anode. Energy and Environmental Science. 18(4), 1683–1695."},"title":"Modulating the solvation structure to enhance amorphous solid electrolyte interface formation for ultra-stable aqueous zinc anode","OA_type":"closed access","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"No","department":[{"_id":"MaIb"}],"date_published":"2025-02-21T00:00:00Z","language":[{"iso":"eng"}],"year":"2025","type":"journal_article","publication_identifier":{"eissn":["1754-5706"],"issn":["1754-5692"]},"day":"21","date_updated":"2025-07-10T11:51:27Z","quality_controlled":"1","acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"NanoFab"}],"isi":1,"status":"public","month":"02","publication":"Energy and Environmental Science","abstract":[{"text":"Electrolyte additives are extensively validated effective in mitigating dendrite growth and parasitic reactions in aqueous zinc-ion batteries (AZIBs). Nonetheless, the mechanisms by which additives influence the formation and characteristics of the inorganic solid–electrolyte interphase (SEI) are not yet fully elucidated. Herein, we investigate how Zn(CF3COO)2 additives influence solvation structure and elucidate the mechanism by which these additives promote the dual reduction of anions. Through cryo-transmission electron microscopy analysis, we identified the SEI as a highly amorphous ZnS/ZnF2 phase. This amorphous hybrid SEI demonstrates exceptional stability, mechanical robustness, and high Zn2+ conductivity, effectively mitigating parasitic reactions and enhancing Zn plating/stripping reversibility. Even under elevated current densities, the Zn anode exhibits ultra-stable longevity and ultra-high reversibility. This study provides a comprehensive understanding of the intrinsic mechanisms governing solvation structure modulation that lead to the formation of amorphous hybrid SEI, underscoring their efficacy in enhancing the performance and durability of AZIBs.","lang":"eng"}],"acknowledgement":"The authors acknowledge financial support from the Joint Fund of Henan Province Science and Technology R&D Program (235200810097) and the Generalitat de Catalunya (2021SGR01581). This research was supported by the Scientific Service Units (SSU) of ISTA Austria through resources provided by the Electron Microscopy Facility (EMF) and the Nanofabrication Facility (NFF). G. Z. and J. L. thank the China Scholarship Council (CSC) for the scholarship support.","article_type":"original","publisher":"Royal Society of Chemistry","page":"1683-1695","scopus_import":"1","date_created":"2025-01-19T23:01:52Z","_id":"18853","external_id":{"isi":["001389898000001"]},"oa_version":"None","doi":"10.1039/d4ee03750b","author":[{"first_name":"Guifang","last_name":"Zeng","full_name":"Zeng, Guifang"},{"last_name":"Sun","full_name":"Sun, Qing","first_name":"Qing"},{"first_name":"Sharona","id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc","last_name":"Horta","full_name":"Horta, Sharona"},{"last_name":"Martínez-Alanis","full_name":"Martínez-Alanis, Paulina R.","first_name":"Paulina R."},{"first_name":"Peng","full_name":"Wu, Peng","last_name":"Wu"},{"first_name":"Jing","last_name":"Li","full_name":"Li, Jing"},{"first_name":"Shang","full_name":"Wang, Shang","last_name":"Wang"},{"last_name":"Ibáñez","orcid":"0000-0001-5013-2843","full_name":"Ibáñez, Maria","first_name":"Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Yanhong","full_name":"Tian, Yanhong","last_name":"Tian"},{"full_name":"Ci, Lijie","last_name":"Ci","first_name":"Lijie"},{"last_name":"Cabot","full_name":"Cabot, Andreu","first_name":"Andreu"}],"intvolume":"        18","publication_status":"published","issue":"4"},{"intvolume":"        25","issue":"7","publication_status":"published","PlanS_conform":"1","external_id":{"isi":["001457747000001"]},"oa_version":"Published Version","doi":"10.1109/jsen.2025.3533113","author":[{"first_name":"Roger","last_name":"Hasler","full_name":"Hasler, Roger"},{"full_name":"Livio, Pietro A.","last_name":"Livio","first_name":"Pietro A."},{"first_name":"Anil","last_name":"Bozdogan","full_name":"Bozdogan, Anil"},{"first_name":"Stefan","last_name":"Fossati","full_name":"Fossati, Stefan"},{"last_name":"Hageneder","full_name":"Hageneder, Simone","first_name":"Simone"},{"first_name":"Verónica","full_name":"Montes-García, Verónica","last_name":"Montes-García"},{"full_name":"Movilli, Jacopo","last_name":"Movilli","first_name":"Jacopo"},{"first_name":"Taghi","full_name":"Moazzenzade, Taghi","last_name":"Moazzenzade"},{"first_name":"Luna","last_name":"Loohuis","full_name":"Loohuis, Luna"},{"full_name":"Reiner-Rozman, Ciril","last_name":"Reiner-Rozman","first_name":"Ciril"},{"full_name":"Tamayo, Adrián","last_name":"Tamayo","first_name":"Adrián"},{"first_name":"Christine","id":"bd3fceba-dc74-11ea-a0a7-c17f71817366","last_name":"Fiedler","full_name":"Fiedler, Christine"},{"first_name":"Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87","last_name":"Ibáñez","orcid":"0000-0001-5013-2843","full_name":"Ibáñez, Maria"},{"first_name":"Christoph","last_name":"Kleber","full_name":"Kleber, Christoph"},{"first_name":"Jurriaan","last_name":"Huskens","full_name":"Huskens, Jurriaan"},{"full_name":"Dostalek, Jakub","last_name":"Dostalek","first_name":"Jakub"},{"last_name":"Samorì","full_name":"Samorì, Paolo","first_name":"Paolo"},{"last_name":"Knoll","full_name":"Knoll, Wolfgang","first_name":"Wolfgang"}],"file":[{"file_name":"2025_IEEESensor_Hasler.pdf","creator":"dernst","date_created":"2025-12-30T07:59:13Z","date_updated":"2025-12-30T07:59:13Z","success":1,"checksum":"9cdd4017025a3add6198ed84798319e8","file_size":2214584,"file_id":"20887","content_type":"application/pdf","access_level":"open_access","relation":"main_file"}],"quality_controlled":"1","ddc":["540"],"acknowledged_ssus":[{"_id":"EM-Fac"}],"isi":1,"publication":"IEEE Sensors Journal","month":"04","oa":1,"status":"public","article_type":"original","acknowledgement":"We thank the Electron Microscopy Facility at ISTA for their support with sputter coating the FO probes and NOSI GmbH for their support with 3D printing.","abstract":[{"lang":"eng","text":"We present a novel, portable sensor platform that enables concurrent monitoring of surface mass and charge density variations at thin biointerfaces. This platform combines a coplanar-gated field-effect transistor (FET) architecture with grating-coupled surface plasmon resonance (SPR), yielding an integrated disposable sensor chip prepared by nanoimprint and maskless photolithography techniques. The sensor chip design is suitable for scalable production and relies on reduced graphene oxide (rGO), serving as the FET’s semiconductor material for the electronic readout, and a metallic gate electrode surface that is corrugated with a multi-diffractive structure for optical probing with resonantly excited surface plasmons. Together with its integration in a compact instrumentation this results in a form factor optimized solution for dual-mode investigations without compromising the optical or electronic sensor performance. A poly-L-lysine (PLL) – based thin linker layer was deployed at the sensor surface to covalently attach azide-conjugated biomolecules by using incorporated “clickable” dibenzocyclooctyne (DBCO) moieties. Interestingly, the dual-mode measurements allow elucidating the role of the globular nature of the PLL chains when increasing the density of DBCO attached to their backbone, leading to PLL folding and internalization of DBCO moieties, and thus reducing the coupling yield for the used DNA oligomers. We envision that this platform can be employed to studying a range of other biointerface architectures and biomolecular interaction phenomena, which are inherently tied to mass and charge density variations."}],"publisher":"IEEE","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"_id":"19037","OA_place":"publisher","page":"10521-10529","date_created":"2025-02-17T09:22:26Z","scopus_import":"1","volume":25,"title":"Dual electronic and optical monitoring of biointerfaces by a grating-structured coplanar-gated field-effect transistor","citation":{"mla":"Hasler, Roger, et al. “Dual Electronic and Optical Monitoring of Biointerfaces by a Grating-Structured Coplanar-Gated Field-Effect Transistor.” <i>IEEE Sensors Journal</i>, vol. 25, no. 7, IEEE, 2025, pp. 10521–29, doi:<a href=\"https://doi.org/10.1109/jsen.2025.3533113\">10.1109/jsen.2025.3533113</a>.","ista":"Hasler R, Livio PA, Bozdogan A, Fossati S, Hageneder S, Montes-García V, Movilli J, Moazzenzade T, Loohuis L, Reiner-Rozman C, Tamayo A, Fiedler C, Ibáñez M, Kleber C, Huskens J, Dostalek J, Samorì P, Knoll W. 2025. Dual electronic and optical monitoring of biointerfaces by a grating-structured coplanar-gated field-effect transistor. IEEE Sensors Journal. 25(7), 10521–10529.","short":"R. Hasler, P.A. Livio, A. Bozdogan, S. Fossati, S. Hageneder, V. Montes-García, J. Movilli, T. Moazzenzade, L. Loohuis, C. Reiner-Rozman, A. Tamayo, C. Fiedler, M. Ibáñez, C. Kleber, J. Huskens, J. Dostalek, P. Samorì, W. Knoll, IEEE Sensors Journal 25 (2025) 10521–10529.","chicago":"Hasler, Roger, Pietro A. Livio, Anil Bozdogan, Stefan Fossati, Simone Hageneder, Verónica Montes-García, Jacopo Movilli, et al. “Dual Electronic and Optical Monitoring of Biointerfaces by a Grating-Structured Coplanar-Gated Field-Effect Transistor.” <i>IEEE Sensors Journal</i>. IEEE, 2025. <a href=\"https://doi.org/10.1109/jsen.2025.3533113\">https://doi.org/10.1109/jsen.2025.3533113</a>.","apa":"Hasler, R., Livio, P. A., Bozdogan, A., Fossati, S., Hageneder, S., Montes-García, V., … Knoll, W. (2025). Dual electronic and optical monitoring of biointerfaces by a grating-structured coplanar-gated field-effect transistor. <i>IEEE Sensors Journal</i>. IEEE. <a href=\"https://doi.org/10.1109/jsen.2025.3533113\">https://doi.org/10.1109/jsen.2025.3533113</a>","ama":"Hasler R, Livio PA, Bozdogan A, et al. Dual electronic and optical monitoring of biointerfaces by a grating-structured coplanar-gated field-effect transistor. <i>IEEE Sensors Journal</i>. 2025;25(7):10521-10529. doi:<a href=\"https://doi.org/10.1109/jsen.2025.3533113\">10.1109/jsen.2025.3533113</a>","ieee":"R. Hasler <i>et al.</i>, “Dual electronic and optical monitoring of biointerfaces by a grating-structured coplanar-gated field-effect transistor,” <i>IEEE Sensors Journal</i>, vol. 25, no. 7. IEEE, pp. 10521–10529, 2025."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_type":"hybrid","article_processing_charge":"Yes (in subscription journal)","has_accepted_license":"1","department":[{"_id":"MaIb"}],"date_published":"2025-04-01T00:00:00Z","language":[{"iso":"eng"}],"type":"journal_article","publication_identifier":{"eissn":["1558-1748"],"issn":["1530-437X"]},"year":"2025","file_date_updated":"2025-12-30T07:59:13Z","date_updated":"2026-02-16T11:50:01Z","day":"01"},{"page":"845-850","date_created":"2025-03-09T23:01:26Z","scopus_import":"1","_id":"19364","acknowledgement":"This work was supported by the Scientific Service Units (SSU) of ISTA through resources provided by the Electron Microscopy Facility (EMF), the Lab Support Facility (LSF), the Communication & Events facility, the Miba Machine Shop, and the Nanofabrication Facility (NNF). The Mechanical Response of Materials (MRM) Service Unit of the Technical University of Wien is acknowledged for Mechanical tests. X. L. Yan and S. Bühler-Paschen (Institute of Solid-State Physics, Technical University of Wien) are acknowledged for granting us access to their equipment, which allowed us to perform independent corroborative measurements. M. Qin is acknowledged for help with Au deposition and wire bonding for samples used for PPMS measurements. The lab of B. Hof and Z. Lu is acknowledged for help with rheological properties measurements. The members of the Ibáñez research group, especially N. Jakhar, C. Fiedler, and T. Kleinhanns, are acknowledged for their feedback on the manuscript and fruitful discussions. This work was financially supported by ISTA and the Werner Siemens Foundation.","article_type":"original","abstract":[{"text":"Thermoelectric coolers (TECs) are pivotal in modern heat management but face limitations in efficiency and manufacturing scalability. We address these challenges by using an extrusion-based 3D printing technique to fabricate high-performance thermoelectric materials. Our ink formulations ensure the integrity of the 3D-printed structure and effective particle bonding during sintering, achieving record-high figure of merit (zT) values of 1.42 for p-type bismuth antimony telluride [(Bi,Sb)2Te3] and 1.3 for n-type silver selenide (Ag2Se) materials at room temperature. The resulting TEC demonstrates a cooling temperature gradient of 50°C in air. Moreover, this scalable and cost-effective method circumvents energy-intensive and time-consuming steps, such as ingot preparation and subsequently machining processes, offering a transformative solution for thermoelectric device production and heralding a new era of efficient and sustainable thermoelectric technologies.","lang":"eng"}],"publisher":"AAAS","isi":1,"corr_author":"1","status":"public","month":"02","publication":"Science","quality_controlled":"1","acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"LifeSc"},{"_id":"M-Shop"},{"_id":"NanoFab"}],"publication_identifier":{"eissn":["1095-9203"]},"type":"journal_article","year":"2025","day":"20","date_updated":"2026-04-28T13:43:53Z","department":[{"_id":"MaIb"}],"language":[{"iso":"eng"}],"date_published":"2025-02-20T00:00:00Z","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","OA_type":"closed access","article_processing_charge":"No","volume":387,"project":[{"name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery","_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A"}],"citation":{"chicago":"Xu, Shengduo, Sharona Horta, Abayomi Q Lawal, Krishnendu Maji, Magali Lorion, and Maria Ibáñez. “Interfacial Bonding Enhances Thermoelectric Cooling in 3D-Printed Materials.” <i>Science</i>. AAAS, 2025. <a href=\"https://doi.org/10.1126/science.ads0426\">https://doi.org/10.1126/science.ads0426</a>.","apa":"Xu, S., Horta, S., Lawal, A. Q., Maji, K., Lorion, M., &#38; Ibáñez, M. (2025). Interfacial bonding enhances thermoelectric cooling in 3D-printed materials. <i>Science</i>. AAAS. <a href=\"https://doi.org/10.1126/science.ads0426\">https://doi.org/10.1126/science.ads0426</a>","ieee":"S. Xu, S. Horta, A. Q. Lawal, K. Maji, M. Lorion, and M. Ibáñez, “Interfacial bonding enhances thermoelectric cooling in 3D-printed materials,” <i>Science</i>, vol. 387, no. 6736. AAAS, pp. 845–850, 2025.","ama":"Xu S, Horta S, Lawal AQ, Maji K, Lorion M, Ibáñez M. Interfacial bonding enhances thermoelectric cooling in 3D-printed materials. <i>Science</i>. 2025;387(6736):845-850. doi:<a href=\"https://doi.org/10.1126/science.ads0426\">10.1126/science.ads0426</a>","ista":"Xu S, Horta S, Lawal AQ, Maji K, Lorion M, Ibáñez M. 2025. Interfacial bonding enhances thermoelectric cooling in 3D-printed materials. Science. 387(6736), 845–850.","mla":"Xu, Shengduo, et al. “Interfacial Bonding Enhances Thermoelectric Cooling in 3D-Printed Materials.” <i>Science</i>, vol. 387, no. 6736, AAAS, 2025, pp. 845–50, doi:<a href=\"https://doi.org/10.1126/science.ads0426\">10.1126/science.ads0426</a>.","short":"S. Xu, S. Horta, A.Q. Lawal, K. Maji, M. Lorion, M. Ibáñez, Science 387 (2025) 845–850."},"title":"Interfacial bonding enhances thermoelectric cooling in 3D-printed materials","publication_status":"published","issue":"6736","intvolume":"       387","doi":"10.1126/science.ads0426","author":[{"last_name":"Xu","full_name":"Xu, Shengduo","first_name":"Shengduo","id":"12ab8624-4c8a-11ec-9e11-e1ac2438f22f"},{"full_name":"Horta, Sharona","last_name":"Horta","id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc","first_name":"Sharona"},{"full_name":"Lawal, Abayomi Q","last_name":"Lawal","id":"5bdaf946-5355-11ee-ae5a-8061700bd605","first_name":"Abayomi Q"},{"full_name":"Maji, Krishnendu","last_name":"Maji","id":"76bc9e9f-ba0b-11ee-8184-90edabd17a58","first_name":"Krishnendu"},{"id":"bc07ac4d-142e-11eb-a9d5-d72db792859d","first_name":"Magali","full_name":"Lorion, Magali","last_name":"Lorion"},{"last_name":"Ibáñez","orcid":"0000-0001-5013-2843","full_name":"Ibáñez, Maria","first_name":"Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87"}],"oa_version":"None","external_id":{"pmid":["39977506"],"isi":["001514422600026"]},"pmid":1,"related_material":{"link":[{"url":"https://ista.ac.at/en/news/cooling-materials-out-of-the-3d-printer/","relation":"press_release","description":"News on ISTA website"}]}},{"external_id":{"isi":["001468606700001"],"pmid":["40237414"]},"pmid":1,"doi":"10.1021/acsnano.5c03074","author":[{"last_name":"Li","full_name":"Li, Jing","first_name":"Jing"},{"full_name":"Zeng, Guifang","last_name":"Zeng","first_name":"Guifang"},{"full_name":"Horta, Sharona","last_name":"Horta","id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc","first_name":"Sharona"},{"first_name":"Paulina R.","full_name":"Martínez-Alanis, Paulina R.","last_name":"Martínez-Alanis"},{"full_name":"Jacas Biendicho, Jordi","last_name":"Jacas Biendicho","first_name":"Jordi"},{"orcid":"0000-0001-5013-2843","last_name":"Ibáñez","full_name":"Ibáñez, Maria","first_name":"Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Xu, Bingang","last_name":"Xu","first_name":"Bingang"},{"full_name":"Ci, Lijie","last_name":"Ci","first_name":"Lijie"},{"first_name":"Andreu","last_name":"Cabot","full_name":"Cabot, Andreu"},{"first_name":"Qing","last_name":"Sun","full_name":"Sun, Qing"}],"oa_version":"None","issue":"16","publication_status":"published","intvolume":"        19","OA_type":"closed access","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","article_processing_charge":"No","volume":19,"title":"Crystallographic engineering in micron-sized SiOx anode material toward stable high-energy-density Lithium-Ion batteries","citation":{"short":"J. Li, G. Zeng, S. Horta, P.R. Martínez-Alanis, J. Jacas Biendicho, M. Ibáñez, B. Xu, L. Ci, A. Cabot, Q. Sun, ACS Nano 19 (2025) 16096–16109.","ista":"Li J, Zeng G, Horta S, Martínez-Alanis PR, Jacas Biendicho J, Ibáñez M, Xu B, Ci L, Cabot A, Sun Q. 2025. Crystallographic engineering in micron-sized SiOx anode material toward stable high-energy-density Lithium-Ion batteries. ACS Nano. 19(16), 16096–16109.","mla":"Li, Jing, et al. “Crystallographic Engineering in Micron-Sized SiOx Anode Material toward Stable High-Energy-Density Lithium-Ion Batteries.” <i>ACS Nano</i>, vol. 19, no. 16, American Chemical Society, 2025, pp. 16096–109, doi:<a href=\"https://doi.org/10.1021/acsnano.5c03074\">10.1021/acsnano.5c03074</a>.","ieee":"J. Li <i>et al.</i>, “Crystallographic engineering in micron-sized SiOx anode material toward stable high-energy-density Lithium-Ion batteries,” <i>ACS Nano</i>, vol. 19, no. 16. American Chemical Society, pp. 16096–16109, 2025.","chicago":"Li, Jing, Guifang Zeng, Sharona Horta, Paulina R. Martínez-Alanis, Jordi Jacas Biendicho, Maria Ibáñez, Bingang Xu, Lijie Ci, Andreu Cabot, and Qing Sun. “Crystallographic Engineering in Micron-Sized SiOx Anode Material toward Stable High-Energy-Density Lithium-Ion Batteries.” <i>ACS Nano</i>. American Chemical Society, 2025. <a href=\"https://doi.org/10.1021/acsnano.5c03074\">https://doi.org/10.1021/acsnano.5c03074</a>.","apa":"Li, J., Zeng, G., Horta, S., Martínez-Alanis, P. R., Jacas Biendicho, J., Ibáñez, M., … Sun, Q. (2025). Crystallographic engineering in micron-sized SiOx anode material toward stable high-energy-density Lithium-Ion batteries. <i>ACS Nano</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsnano.5c03074\">https://doi.org/10.1021/acsnano.5c03074</a>","ama":"Li J, Zeng G, Horta S, et al. Crystallographic engineering in micron-sized SiOx anode material toward stable high-energy-density Lithium-Ion batteries. <i>ACS Nano</i>. 2025;19(16):16096-16109. doi:<a href=\"https://doi.org/10.1021/acsnano.5c03074\">10.1021/acsnano.5c03074</a>"},"year":"2025","publication_identifier":{"issn":["1936-0851"],"eissn":["1936-086X"]},"type":"journal_article","date_updated":"2025-09-30T12:19:51Z","day":"16","department":[{"_id":"MaIb"}],"date_published":"2025-04-16T00:00:00Z","language":[{"iso":"eng"}],"isi":1,"month":"04","publication":"ACS Nano","status":"public","quality_controlled":"1","acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"NanoFab"}],"_id":"19629","date_created":"2025-04-27T22:02:14Z","scopus_import":"1","page":"16096-16109","article_type":"original","abstract":[{"text":"The SiOx anode exhibits a high specific capacity and commendable durability for lithium-ion batteries (LIBs). However, its practical application is hindered by significant volumetric fluctuations during lithiation/delithiation, alongside a metastable nature, which induces mechanical instability and irreversible lithium consumption, ultimately impairing long-term capacity retention in full-battery cell configurations. In this study, we present a phase-engineering approach designed to improve the structural stability of SiOx anodes for LIB applications. By incorporating lithium fluoride, amorphous SiOx undergoes partial transformation into a quartz-like phase, which enhances mechanical integrity and mitigates irreversible lithium loss. This modified anode demonstrates significantly improved stability and prolonged cycle lifespan. Through a combination of multiscale simulations and in situ characterizations, we elucidate the stabilization mechanisms conferred by the quartz phase, providing critical insights into the role of SiOx’s crystal structure in influencing degradation pathways. This work introduces an accessible and efficient method for controlling the crystallinity of SiOx, offering a practical solution to enhance the durability of high-energy-density LIBs.","lang":"eng"}],"acknowledgement":"This work was supported by the Guangdong Basic and Applied Basic Research Foundation (2023A1515110828) and the Generalitat de Catalunya (2021SGR01581). This research was supported by the Scientific Service Units (SSU) of ISTA Austria through resources provided by the Electron Microscopy Facility (EMF) and the Nanofabrication Facility (NFF).","publisher":"American Chemical Society"},{"publication_status":"published","issue":"22","intvolume":"       147","external_id":{"pmid":["40402919"],"isi":["001493301300001"]},"pmid":1,"author":[{"first_name":"Pranav","last_name":"Negi","full_name":"Negi, Pranav"},{"full_name":"He, Bin","last_name":"He","first_name":"Bin"},{"first_name":"Denis","last_name":"Ukolov","full_name":"Ukolov, Denis"},{"full_name":"Horta, Sharona","last_name":"Horta","id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc","first_name":"Sharona"},{"full_name":"Maji, Krishnendu","last_name":"Maji","id":"76bc9e9f-ba0b-11ee-8184-90edabd17a58","first_name":"Krishnendu"},{"first_name":"Ning","full_name":"Mao, Ning","last_name":"Mao"},{"last_name":"Peshcherenko","full_name":"Peshcherenko, Nikolai","first_name":"Nikolai"},{"first_name":"Premakumar","full_name":"Yanda, Premakumar","last_name":"Yanda"},{"first_name":"Mengyu","last_name":"Yao","full_name":"Yao, Mengyu"},{"last_name":"Dutta","full_name":"Dutta, Moinak","first_name":"Moinak"},{"full_name":"Robredo, Iñigo","last_name":"Robredo","first_name":"Iñigo"},{"last_name":"Iraola","full_name":"Iraola, Mikel","first_name":"Mikel"},{"full_name":"Vergniory, Maia G.","last_name":"Vergniory","first_name":"Maia G."},{"last_name":"Lemmens","full_name":"Lemmens, Peter","first_name":"Peter"},{"first_name":"Yang","full_name":"Zhang, Yang","last_name":"Zhang"},{"last_name":"Shekhar","full_name":"Shekhar, Chandra","first_name":"Chandra"},{"last_name":"Ibáñez","orcid":"0000-0001-5013-2843","full_name":"Ibáñez, Maria","first_name":"Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Felser","full_name":"Felser, Claudia","first_name":"Claudia"},{"first_name":"Subhajit","last_name":"Roychowdhury","full_name":"Roychowdhury, Subhajit"}],"doi":"10.1021/jacs.5c01700","oa_version":"None","status":"public","publication":"Journal of the American Chemical Society","month":"05","isi":1,"acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"NanoFab"}],"quality_controlled":"1","date_created":"2025-06-03T07:30:22Z","scopus_import":"1","page":"18704-18711","_id":"19779","publisher":"American Chemical Society","article_type":"original","acknowledgement":"P.N. thanks the IISER Bhopal for a fellowship. S.R.C. acknowledges generous funding support and CIF facility (PXRD) from IISER Bhopal. C.F. acknowledges the Deutsche Forschungsgemeinschaft (DFG) under SFB1143 (project no. 247310070), the Würzburg-Dresden Cluster of Excellence on Complexity and Topology in Quantum Matter─ct.qmat (EXC 2147, project no. 390858490) and the QUAST-FOR5249-449872909. P.L. and D.U. acknowledge support by DFG EXC-2123 QuantumFrontiers–390837967. The work of M.I. was funded by the European Union NextGenerationEU/PRTR-C17.I1, as well as by the IKUR Strategy under the collaboration agreement between Ikerbasque Foundation and DIPC on behalf of the Department of Education of the Basque Government. M.G.V. and M.I. thank support to the Spanish Ministerio de Ciencia e Innovacion (grant PID2022-142008NBI00). Y.Z. is supported by the Max Planck Partner lab from Max Planck Institute Chemical Physics of Solids. We acknowledge Petra III-DESY for the XPDF measurements and PXRD measurements. This research was supported by the Scientific Service Units (SSU) of ISTA Austria through resources provided by Electron Microscopy Facility (EMF) and the Nanofabrication Facility (NNF). ISTA acknowledges the Werner Siemens Foundation (WSS) for financial support.","abstract":[{"lang":"eng","text":"The transverse thermoelectric (Nernst) effect is a powerful probe for studying the electronic and structural properties of materials. In this study, we employ transverse thermoelectric measurements to investigate the ferroelectric distortion in the topological crystalline insulator (TCI) Pb0.60Sn0.40Te, a compound derived from PbTe and SnTe, known for their exceptional thermoelectric performance and distinct ferroelectric properties. By leveraging Nernst measurements, we provide direct evidence of ferroelectric distortion in this TCI, corroborated by Shubnikov–de Haas quantum oscillations that confirm the presence of two topologically nontrivial Fermi pockets. Density functional theory calculations show that these pockets originate from the L and T points in the Brillouin zone of the distorted structure within the TCI phase. Raman spectroscopy further identifies a structural phase transition below 50 K, consistent with the quantum oscillation observations. This observation is further substantiated by temperature-dependent synchrotron X-ray pair distribution function analysis and transmission electron microscopy, which confirm the local off-centering of cations at low temperature. These findings underscore the potential of transverse thermoelectric measurements in unveiling ferroelectric distortions and their role in modulating topological quantum states, opening new directions for research into the synergy between ferroelectricity and topological phases."}],"article_processing_charge":"No","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_type":"closed access","citation":{"short":"P. Negi, B. He, D. Ukolov, S. Horta, K. Maji, N. Mao, N. Peshcherenko, P. Yanda, M. Yao, M. Dutta, I. Robredo, M. Iraola, M.G. Vergniory, P. Lemmens, Y. Zhang, C. Shekhar, M. Ibáñez, C. Felser, S. Roychowdhury, Journal of the American Chemical Society 147 (2025) 18704–18711.","ista":"Negi P, He B, Ukolov D, Horta S, Maji K, Mao N, Peshcherenko N, Yanda P, Yao M, Dutta M, Robredo I, Iraola M, Vergniory MG, Lemmens P, Zhang Y, Shekhar C, Ibáñez M, Felser C, Roychowdhury S. 2025. Evidence of ferroelectric distortions in topological crystalline insulators via transverse thermoelectric measurements. Journal of the American Chemical Society. 147(22), 18704–18711.","mla":"Negi, Pranav, et al. “Evidence of Ferroelectric Distortions in Topological Crystalline Insulators via Transverse Thermoelectric Measurements.” <i>Journal of the American Chemical Society</i>, vol. 147, no. 22, American Chemical Society, 2025, pp. 18704–11, doi:<a href=\"https://doi.org/10.1021/jacs.5c01700\">10.1021/jacs.5c01700</a>.","chicago":"Negi, Pranav, Bin He, Denis Ukolov, Sharona Horta, Krishnendu Maji, Ning Mao, Nikolai Peshcherenko, et al. “Evidence of Ferroelectric Distortions in Topological Crystalline Insulators via Transverse Thermoelectric Measurements.” <i>Journal of the American Chemical Society</i>. American Chemical Society, 2025. <a href=\"https://doi.org/10.1021/jacs.5c01700\">https://doi.org/10.1021/jacs.5c01700</a>.","apa":"Negi, P., He, B., Ukolov, D., Horta, S., Maji, K., Mao, N., … Roychowdhury, S. (2025). Evidence of ferroelectric distortions in topological crystalline insulators via transverse thermoelectric measurements. <i>Journal of the American Chemical Society</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/jacs.5c01700\">https://doi.org/10.1021/jacs.5c01700</a>","ama":"Negi P, He B, Ukolov D, et al. Evidence of ferroelectric distortions in topological crystalline insulators via transverse thermoelectric measurements. <i>Journal of the American Chemical Society</i>. 2025;147(22):18704-18711. doi:<a href=\"https://doi.org/10.1021/jacs.5c01700\">10.1021/jacs.5c01700</a>","ieee":"P. Negi <i>et al.</i>, “Evidence of ferroelectric distortions in topological crystalline insulators via transverse thermoelectric measurements,” <i>Journal of the American Chemical Society</i>, vol. 147, no. 22. American Chemical Society, pp. 18704–18711, 2025."},"title":"Evidence of ferroelectric distortions in topological crystalline insulators via transverse thermoelectric measurements","volume":147,"project":[{"_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A","name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery"}],"date_updated":"2025-12-30T08:32:19Z","day":"22","publication_identifier":{"issn":["0002-7863"],"eissn":["1520-5126"]},"type":"journal_article","year":"2025","date_published":"2025-05-22T00:00:00Z","language":[{"iso":"eng"}],"department":[{"_id":"MaIb"}]}]
