@article{21710, abstract = {Early results from JWST suggest that Epoch of Reionization (EoR) galaxies produce copious ionizing photons, which, if they escape efficiently, could cause reionization to occur too early. We study this problem using JWST imaging and prism spectroscopy for 412 galaxies at 4.5 < z < 9.0. We fit these data simultaneously with stellar population and nebular emission models that include a parameter for the fraction of ionizing photons that escape the galaxy, fesc. We find that the ionization production efficiency, ξion = Q(H0)/LUV, increases with redshift and decreasing UV luminosity, but shows significant scatter, (log ion z, MUV) 0.3 dex. The inferred escape fractions averaged over the population are low, ranging from〈fesc〉 ≃ 2.6% ± 1.4% at 6 < z < 9 to 6.5% ± 2.2% at 4.5 < z < 6, with weak or no indication of evolution with redshift. This implies that in our models most of the ionizing photons need to be absorbed to account for the nebular emission. We compute the impact of our results on reionization, including the distributions for ξion and fesc, and the evolution and uncertainty of the UV luminosity function. Considering galaxies brighter than MUV < −16 mag would produce an intergalactic medium hydrogen-ionized fraction of xe = 0.5 at 5.3 < z < 5.8, possibly too late compared to constraints from from quasistellar object (QSO) sight lines. Including fainter galaxies, MUV < −14 mag, we obtain xe = 0.5 at 6.0 < z < 8.1, fully consistent with QSO and cosmic microwave background data. This implies that EoR galaxies produce plenty of ionizing photons, but that these do not efficiently escape. This may be a result of high gas column densities combined with burstier star formation histories, which limit the time massive stars are able to clear channels through the gas for ionizing photons to escape.}, author = {Papovich, Casey and Cole, Justin W. and Hu, Weida and Finkelstein, Steven L. and Shen, Lu and Arrabal Haro, Pablo and Amorín, Ricardo O. and Backhaus, Bren E. and Bagley, Micaela B. and Bhatawdekar, Rachana and Calabrò, Antonello and Carnall, Adam C. and Cleri, Nikko J. and Daddi, Emanuele and Dickinson, Mark and Grogin, Norman A. and Holwerda, Benne W. and Jaskot, Anne E. and Koekemoer, Anton M. and Llerena, Mario and Lucas, Ray A. and Mascia, Sara and Pacucci, Fabio and Pentericci, Laura and Pérez-González, Pablo G. and Pirzkal, Nor and Raghunathan, Srinivasan and Seillé, Lise Marie and Somerville, Rachel S. and Yung, L. Y.Aaron}, issn = {1538-4357}, journal = {The Astrophysical Journal}, number = {1}, publisher = {IOP Publishing}, title = {{Galaxies in the epoch of reionization are all bark and no bite-plenty of ionizing photons, low escape fractions}}, doi = {10.3847/1538-4357/ae3b25}, volume = {1000}, year = {2026}, } @article{21711, abstract = {Background: Low-volume trapping columns are essential for sample enrichment, desalting, and injection profile focusing on nano-LC–MS-based proteomics. They enable higher sample loading, improve chromatographic performance, and protect the analytical column by removing salts and contaminants. Recently, monolithic trap columns with micropillar architecture have emerged as alternatives to conventionally packed traps. This study compares the performance of a packed and a micropillar monolithic trap column for the analysis of tryptic peptides. Methods: A tryptic digest of HeLa cell lysate was analyzed under identical LC–MS conditions using both trap types. Peptides were detected at 214 nm and analyzed by nano-ESI on a Q Exactive Plus Orbitrap. Data were searched against the human UniProt database (February 2023) using FragPipe v20.0, and statistical evaluation of MaxLFQ intensities was performed in Perseus using Welch’s t-test and clustering analysis. Results: Over 2500 proteins were identified with both setups. The packed trap column yielded more total peptides, particularly those with post-translational modifications and higher hydrophilicity, whereas the monolithic column favored peptides of intermediate hydrophobicity. Chromatographic profiles confirmed a slight reduction in the trapping efficiency of hydrophilic peptides by the monolithic trap. Conclusions: Trap column design significantly influences peptide recovery and proteome coverage.}, author = {Miletić Vukajlović, Jadranka and Ilić, Bojana and Bruszel, Bella and Panić-Janković, Tanja and Mitulović, Goran}, issn = {2227-7382}, journal = {Proteomes}, number = {1}, publisher = {MDPI}, title = {{Comparison of the trapping efficiency for tryptic peptides on particle-packed and micro-pillar trap columns for proteomics analyses}}, doi = {10.3390/proteomes14010010}, volume = {14}, year = {2026}, } @article{21712, abstract = {Supermassive black hole binary (SMBHB) systems are expected to form as a consequence of galaxy mergers. At subparsec separations, SMBHBs can be identified as quasars with periodic variability, with previous periodicity searches uncovering significant candidates. However, these searches focused primarily on sinusoidal signals, while theoretical models and hydrodynamical simulations predict that binaries produce more complex non-sinusoidal pulse shapes. Here we examine the efficacy of the Lomb–Scargle periodogram (LSP; one of the most popular tools for periodicity searches in unevenly sampled lightcurves) to detect periodicities with a sawtooth shape mimicking results of hydrodynamical simulations. We simulate idealized well-sampled lightcurves, lightcurves that mimic the data in the Palomar Transient Factory (PTF) analyzed in M. Charisi et al. (2016), and lightcurves that resemble our expectations for single-band data in the upcoming Legacy Survey of Space and Time (LSST) of the Rubin Observatory. We approximate quasar variability with a damped random walk (DRW) model, inject sinusoidal and sawtooth pulse shapes, and assess their statistical significance. We find that in the presence of red noise, the LSP detects a relatively low fraction of the sinusoidal signals (∼45%, ∼24%, and ∼23%, in the PTF-like, idealized, and LSST-like lightcurves, respectively). The fraction is significantly reduced for sawtooth periodicity (with only ∼9% in PTF-like and ∼1% in idealized and LSST-like lightcurves). These low recovery rates imply that previous searches have missed the large majority of binaries. They also have significant implications for the detection of SMBHBs in upcoming LSST necessitating the development of advanced tools that go beyond the simple LSP.}, author = {Lin, Allison and Charisi, Maria and Haiman, Zoltán}, issn = {1538-4357}, journal = {The Astrophysical Journal}, number = {2}, publisher = {IOP Publishing}, title = {{Lomb-scargle periodogram struggles with non-sinusoidal supermassive Black Hole binary signatures in quasar lightcurves}}, doi = {10.3847/1538-4357/ae29a7}, volume = {997}, year = {2026}, } @article{21713, abstract = {GW231123 represents the most massive binary–black hole merger detected to date, lying firmly within, or even above, the pair-instability mass gap. The component spins are both exceptionally high (a1 = 0.90 +0.10/-0.19, a2 = 0.80 +0.20/-0.51), which is difficult to explain with repeated mergers. Here we show that the black hole spin vectors are closely aligned with each other while significantly tilted relative to the binary’s orbital angular momentum, pointing to a common accretion-driven origin. We examine astrophysical formation channels capable of producing near-equal, high-mass, and mutually aligned spins consistent with GW231123—particularly binaries embedded in AGN disks and Population III remnants, which grew via coherent misaligned gas accretion. We further argue that other high-mass, high-spin events, e.g., GW190521, may share a similar evolutionary pathway. These findings underscore the critical role of sustained, coherent accretion in shaping the most extreme black hole binaries.}, author = {Bartos, Imre and Haiman, Zoltán}, issn = {2041-8213}, journal = {The Astrophysical Journal Letters}, number = {2}, publisher = {IOP Publishing}, title = {{Accretion is all you need: Black Hole spin alignment in merger GW231123 indicates accretion pathway}}, doi = {10.3847/2041-8213/ae2bff}, volume = {996}, year = {2026}, } @article{21714, abstract = {Be stars are rapidly rotating main-sequence stars that play a crucial role in understanding stellar evolution and binary interactions. In this Letter, we propose a new formation scenario for black hole (BH) + Be star binaries (hereafter BHBe binaries), where the Be star is produced through the wind Roche lobe overflow (WRLOF) mechanism. Our analysis is based on numerical simulations of the WRLOF process in massive binaries, building on recent theoretical work. We demonstrate that the WRLOF model can efficiently form BHBe binaries under reasonable assumptions on stellar wind velocities. Using rapid binary population synthesis, we estimate the population of such systems in the Milky Way, predicting ∼1800−3200 currently existing BHBe binaries originating from the WRLOF channel. These systems are characterized by high eccentricities and exceptionally wide orbits, with typical orbital periods exceeding 1000 days and a peak distribution around ∼10,000 days. Due to their long orbital separations, these BHBe binaries are promising targets for future detection via astrometric and interferometric observations.}, author = {Li, Zhenwei and Jia, Shi and Wei, Dandan and Ge, Hongwei and Chen, Hailiang and Zhang, Yangyang and Chen, Xuefei and Han, Zhanwen}, issn = {2041-8213}, journal = {The Astrophysical Journal Letters}, number = {2}, publisher = {IOP Publishing}, title = {{Formation of Be stars via wind accretion: Case study on Black Hole + Be star binaries}}, doi = {10.3847/2041-8213/ae3008}, volume = {996}, year = {2026}, } @article{21715, abstract = {New populations of red active galactic nuclei (known as “little red dots”) discovered by JWST exhibit remarkable spectral energy distributions. Leveraging X-ray through far-infrared observations of two of the most luminous known little red dots, we directly measure their bolometric luminosities. We find evidence that more than half of the bolometric luminosity likely emerges in the rest-frame optical, with Lbol/L5100 = 5, roughly half the value for “standard” active galactic nuclei. Meanwhile, the X-ray emitting corona, UV-emitting blackbody, and reprocessed mid to far-infrared emission are all considerably subdominant, assuming that the far-infrared luminosity is well below current measured limits. We present new bolometric corrections that dramatically lower inferred bolometric luminosities by a factor of 10 compared to published values in the literature. These bolometric corrections are in accord with expectations from models in which gas absorption and reprocessing are responsible for the red rest-frame optical colors of little red dots. We discuss how this lowered luminosity scale suggests a lower mass scale for the population by at least an order of magnitude (e.g., ∼105–107 M⊙ black holes, and ∼108 M⊙ galaxies), alleviating tensions with clustering, overmassive black holes, and the integrated black hole mass density in the Universe.}, author = {Greene, Jenny E. and Setton, David J. and Furtak, Lukas J. and Naidu, Rohan P. and Volonteri, Marta and Dayal, Pratika and Labbe, Ivo and Van Dokkum, Pieter and Bezanson, Rachel and Brammer, Gabriel and Cutler, Sam E. and Glazebrook, Karl and De Graaff, Anna and Hirschmann, Michaela and Hviding, Raphael E. and Kokorev, Vasily and Leja, Joel and Liu, Hanpu and Ma, Yilun and Matthee, Jorryt J and Nanayakkara, Themiya and Oesch, Pascal A. and Pan, Richard and Price, Sedona H. and Spilker, Justin S. and Wang, Bingjie and Weaver, John R. and Whitaker, Katherine E. and Williams, Christina C. and Zitrin, Adi}, issn = {1538-4357}, journal = {The Astrophysical Journal}, number = {2}, publisher = {IOP Publishing}, title = {{What you see is what you get: Empirically measured bolometric luminosities of Little Red Dots}}, doi = {10.3847/1538-4357/ae1836}, volume = {996}, year = {2026}, } @article{21718, abstract = {In this paper, we consider the big algebra recently introduced by Hausel for the GLn-action on the coordinate ring of the matrix space Mat(n,r). In particular, we obtain explicit formulas for the big algebra generators in terms of differential operators with polynomial coefficients. We show that big algebras in type A are commutative and relate them to the Bethe subalgebra in the Yangian Y(gln). We apply these results to big algebras of symmetric powers of the standard representation of GLn. .}, author = {Ngo, Nhok T}, issn = {1815-0659}, journal = {Symmetry, Integrability and Geometry: Methods and Applications}, publisher = {National Academy of Science of Ukraine}, title = {{Big algebra in type A for the coordinate ring of the matrix space}}, doi = {10.3842/SIGMA.2026.024}, volume = {22}, year = {2026}, } @inproceedings{21719, abstract = {We develop a new algorithmic framework for designing approximation algorithms for cut-based optimization problems on capacitated undirected graphs that undergo edge insertions and deletions. Specifically, our framework dynamically maintains a variant of the hierarchical 𝑗-tree decomposition of [Madry FOCS’10], achieving a poly-logarithmic approximation factor to the graph’s cut structure and supporting edge updates in 𝑂⁡(𝑛𝜀) amortized update time, for any arbitrarily small constant 𝜀 ∈(0,1). Consequently, we obtain new trade-offs between approximation and update/query time for fundamental cut-based optimization problems in the fully dynamic setting, including all-pairs minimum cuts, sparsest cut, multi-way cut, and multi-cut. For the last three problems, these trade-offs give the first fully-dynamic algorithms achieving poly-logarithmic approximation in sub-linear time per operation. The main technical ingredient behind our dynamic hierarchy is a dynamic cut-sparsifier algorithm that can handle vertex splits with low recourse. This is achieved by white-boxing the dynamic cut sparsifier construction of [Abraham et al. FOCS’16], based on forest packing, together with new structural insights about the maintenance of these forests under vertex splits. Given the versatility of cut sparsification in both the static and dynamic graph algorithms literature, we believe this construction may be of independent interest.}, author = {Goranci, Gramoz and Henzinger, Monika H and Kiss, Peter and Momeni, Ali and Zöcklein, Gernot}, booktitle = {Proceedings of the 2026 Annual ACM SIAM Symposium on Discrete Algorithms}, isbn = {9781611978971}, issn = {15579468}, pages = {1128--1180}, publisher = {Society for Industrial and Applied Mathematics}, title = {{Dynamic hierarchical j-tree decomposition and its applications}}, doi = {10.1137/1.9781611978971.45}, volume = {2026-January}, year = {2026}, } @article{21725, abstract = {The initial–final mass relation (IFMR) links a star’s birth mass to the mass of its white dwarf (WD) remnant, providing key constraints on stellar evolution. Open clusters offer the most straightforward way to empirically determine the IFMR, as their well-defined ages allow for direct progenitor lifetime estimates. We construct the most comprehensive open cluster WD IFMR to date by combining new spectroscopy of 22 WDs with an extensive literature review of WDs with strong cluster associations. To minimize systematics, we restrict our analysis to spectroscopically confirmed hydrogen-atmosphere (DA) WDs consistent with single-stellar origins. We separately analyze a subset with reliable Gaia-based astrometric membership assessments, as well as a full sample that adds WDs with strong cluster associations whose membership cannot be reliably assessed with Gaia. The Gaia-based sample includes 69 spectroscopically confirmed DA WDs, more than doubling the sample size of previous Gaia-based open cluster IFMRs. The full sample, which includes 53 additional literature WDs, increases the total number of cluster WDs by over 50% relative to earlier works. We provide functional forms for both the Gaia-based and full-sample IFMRs. The Gaia-based result useful for Mi � 2.67 M⊙ is Mf = [0.179 0.100H (Mi 3.84 M )] × (Mi 3.84 M ) + 0.628 M , where H(x) is the Heaviside step function. Comparing our IFMR to recent literature, we identify significant deviations from best-fit IFMRs derived from both Gaia-based volume-limited samples of field WDs and double WD binaries, with the largest discrepancy occurring for initial masses of about 5 M⊙.}, author = {Miller, David R. and Caiazzo, Ilaria and Heyl, Jeremy and Richer, Harvey B. and Hollands, Mark A. and Tremblay, Pier Emmanuel and El-Badry, Kareem and Rodriguez, Antonio C. and Vanderbosch, Zachary P.}, issn = {1538-4357}, journal = {The Astrophysical Journal}, keywords = {White dwarf stars, Open star clusters, Compact objects, Stellar evolution}, number = {1}, publisher = {IOP Publishing}, title = {{The White Dwarf initial–final mass relation from open clusters in Gaia DR3}}, doi = {10.3847/1538-4357/ae18c8}, volume = {996}, year = {2026}, } @unpublished{21737, abstract = {In calculus, l'Hopital's rule provides a simple way to evaluate the limits of quotient functions when both the numerator and denominator vanish. But what happens when we move beyond real functions on a real interval? In this article, we study when the quotient of two complex-valued functions in higher dimension can be defined continuously at the points where both functions vanish. Surprisingly, the answer is far subtler than in the real-valued setting. We provide a complete characterization for the continuity of the quotient function. We also point out why extending this result to smoother quotients remains an intriguing challenge.}, author = {Chern, Albert and Ishida, Sadashige}, booktitle = {arXiv}, keywords = {l’Hopital theorem, complex functions}, title = {{L'Hopital rules for complex-valued functions in higher dimensions}}, doi = {10.48550/ARXIV.2602.09958}, year = {2026}, } @article{21743, abstract = {We present symplectic structures on the shape space of unparameterized space curves that generalize the classical Marsden–Weinstein structure. Our method integrates the Liouville 1-form of the Marsden–Weinstein structure with Riemannian structures that have been introduced in mathematical shape analysis. We also derive Hamiltonian vector fields for several classical Hamiltonian functions with respect to these new symplectic structures.}, author = {Bauer, Martin and Ishida, Sadashige and Michor, Peter W.}, issn = {1432-1467}, journal = {Journal of Nonlinear Science}, number = {2}, publisher = {Springer Nature}, title = {{Symplectic structures on the space of space curves}}, doi = {10.1007/s00332-026-10266-8}, volume = {36}, year = {2026}, } @article{21744, abstract = {The paraventricular hypothalamus (PVH) controls behavioral and physiologic processes, including appetite, social behavior, autonomic outflow, and pituitary hormone secretion. However, molecular markers for centrally projecting PVH neuron populations remain largely undefined, and a complete census of PVH cell types has not been established. Therefore, we performed extensive single-cell/nucleus RNA sequencing to catalog PVH neuron subtypes and multiplexed error-robust fluorescence in situ hybridization (MERFISH) to map them spatially. Our spatial transcriptomic atlas resolves 26 Sim1+ and 29 GABAergic neuron populations from the PVH and surrounding areas. Additionally, projection-based profiling identified neurons that project to the parabrachial region (PB) and spinal cord, helping to determine PVH populations that regulate satiety and sympathetic nervous system activity, respectively. Notably, activation of PB-projecting PVH neurons expressing Brs3 reduces food intake, and silencing them causes obesity. Together, this atlas contributes high-resolution PVH spatial and circuit-based gene expression profiles, representing a valuable resource for the field of homeostasis.}, author = {Li, Yuxi and Butler, Trevor C. and Nardone, Stefano and Jacobs, Christopher L. and Douglass, Amelia May Barnett and Madara, Joseph C. and McDonough, Miriam C. and Tao, Jenkang and Lowenstein, Elijah D. and Wang, Luhong and Pant, Deepti and Walker, Samuel J. and Wang, Annette and Srinivasan, Harini and Yang, Zongfang and Campbell, John N. and Tsai, Linus T. and Lowell, Bradford B. and Resch, Jon M.}, issn = {2211-1247}, journal = {Cell Reports}, number = {2}, publisher = {Elsevier}, title = {{A spatial and projection-based transcriptomic atlas of paraventricular hypothalamic cell types}}, doi = {10.1016/j.celrep.2025.116904}, volume = {45}, year = {2026}, } @article{21745, abstract = {The small DAHe and DAe spectral classes comprise isolated, hydrogen-dominated atmosphere white dwarfs that exhibit variable photometric flux and Balmer line emission. These mysterious systems offer unique insight into the complex interplay between magnetic fields, stellar rotation and atmospheric activity in single white dwarfs. DAHe stars have detectable magnetic fields through Zeeman-split spectral lines, whereas DAe stars lack such splitting. We report the first discovery and characterization of magnetism in the DAe white dwarf WD J165335.21−100116.33 with new time-resolved spectropolarimetry from FORS2. We detect a weak but variable longitudinal magnetic field with values Bz > −9.2 ± 2.4 kG and Bz < −2.2 ± 1.0 kG. Independent ZTF and ATLAS photometry reveal a consistent period of P = 80.3070 ± 0.0007 h. Time-resolved optical spectroscopy obtained with six ground-based instruments demonstrates strong modulation in the strength of the Hα and Hβ Balmer line emission with P = 80.2922 ± 0.0108 h. The photometric flux and Balmer emission strength vary in antiphase, with the strongest magnetic detections coinciding with phases of low photometric flux and strong line emission. These characteristicssupport the theory that a magnetically active, temperature-inverted spot/region is producing an optically thin chromospheric emission region. Comparison with other DAe and DAHe white dwarfsreveals all systems have a strikingly similar antiphase phenomenology, reinforcing the theory that they are subject to a unified physical mechanism. With the detection of a weak magnetic field, we reclassify WD J165335.21−100116.33 as a low-field DAHe white dwarf. }, author = {Elms, Abbigail K. and Bagnulo, Stefano and Tremblay, Pier Emmanuel and Cunningham, Tim and Munday, James and Landstreet, John and El-Badry, Kareem and Caiazzo, Ilaria and Melis, Carl and Pinter, Viktoria and Weinberger, Alycia}, issn = {1365-2966}, journal = {Monthly Notices of the Royal Astronomical Society}, number = {1}, publisher = {Oxford University Press}, title = {{Detection of a weak magnetic field in the Balmer emission line white dwarf WDJ1653−1001}}, doi = {10.1093/mnras/stag505}, volume = {548}, year = {2026}, } @article{21747, abstract = {Entanglement does not always require one particle per party. It was predicted some 30 years ago that a single photon traversing a beam splitter could violate a Bell inequality. Although initially debated, single-photon nonlocality was eventually demonstrated via homodyne measurements. Here, we present an alternate realization that avoids the complexity of homodyne measurements and potential loopholes in their implementation. We violate a Bell inequality by performing joint measurements on two copies of the same single-photon entangled state, where one photon acts as a phase reference for the other, making it self-referential. We observe CHSH parameters of 2.71 = 0.09 and 2.23 = 0.07, depending on the joint measurements implemented. This offers a perspective on single-photon nonlocality and a more accessible experimental route, potentially applicable to general mode-entangled states in diverse platforms.}, author = {Kun, Daniel and Strömberg, Karl T and Dakić, Borivoje and Walther, Philip and Rozema, Lee A.}, issn = {2334-2536}, journal = {Optica}, number = {4}, pages = {745--751}, publisher = {Optica Publishing Group}, title = {{Testing single-photon entanglement using self-referential measurements}}, doi = {10.1364/OPTICA.586172}, volume = {13}, year = {2026}, } @article{21748, abstract = {Cells are defined by lipid membranes that differ in their structure across the tree of life. While the membranes of most bacteria and eukaryotes consist of single-headed bilayer lipids, the membranes of archaea are composed of mixtures of single-headed bilayer lipids and double-headed bolalipids. Archaeal bolalipids can adopt straight or u-shaped conformations, enabling them—together with bilayer lipids—to control whether membranes form bilayer or monolayer structures. Yet, the physical principles governing archaeal membranes remain largely unexplored, especially how membrane structure couples to externally imposed curvature during membrane remodeling. Here, we perform coarse-grained molecular dynamics simulations of toroidal vesicles to systematically probe the effects of all relevant combinations of mean and Gaussian curvatures on shape stability and lipid organization. We find that soft bilayer membranes can sustain all curvatures induced, whereas rigid bolalipid monolayer membranes either transition to different vesicle shapes or rupture. Bilayer-mimicking u-shaped bolalipids and bilayer lipids are spatially accumulated in regions of high mean membrane curvature independent of Gaussian curvature. Our work identifies curvature–composition coupling as a physical signature of archaeal membrane remodeling.}, author = {Frey, Felix F and Santana de Freitas Amaral, Miguel and Šarić, Anđela}, issn = {1089-7690}, journal = {Journal of Chemical Physics}, number = {14}, publisher = {AIP Publishing}, title = {{Cracking donuts and sorting lipids: Geometry controls archaeal membrane stability and lipid organization}}, doi = {10.1063/5.0325170}, volume = {164}, year = {2026}, } @article{21749, abstract = {The collagen triple helix assembles hierarchically into bundled oligomers, solvated networks, and fibers. Synthetic peptide assemblies, driven by supramolecular interactions, can form single triple helices through intrahelical amino acid pairs; however, the principles guiding interhelical associations into higher-order structures remain unclear. Here, we incorporate cation−π and electrostatic charge pairs to probe interhelical interactions and elucidate the mechanisms driving triple helix assembly into fibrils, nanotubes, and nanosheets. Introducing cation−π pairs into a fibrillating collagen mimetic resulted in D-periodic fibrils with pH-sensitive gelation. By alternating the presentation of electrostatic and cation−π pairs, the assembly of another D-periodic fibril featuring inner and outer triple-helical layers was resolved by cryo electron microscopy to a resolution of 8 Å. At physiological pH, antiparallel association of these triple helices leads to the formation of nanotubes. The packing behavior of triple helices correlates with the interhelical interactions, where parallel associations favor fibril formation and antiparallel interactions drive nanotube and nanosheet assembly. These self-assembling triple-helical peptides demonstrate how packing of higher-order structures can be tailored with supramolecular interactions and establish the relationship of different hierarchical collagen-mimetic assemblies as pH-dependent.}, author = {Cole, Carson C. and Kreutzberger, Mark A.B. and Klein, Kevin and Cahue, Kiana A. and Pogostin, Brett H. and Farsheed, Adam C. and Swain, Joseph W.R. and Bui, Thi H. and Dey, Arghadip and Makhoul, Jonathan T. and Dubackic, Marija and Pal, Antara and Olsson, Ulf and Šarić, Anđela and Egelman, Edward H. and Hartgerink, Jeffrey D.}, issn = {1526-4602}, journal = {Biomacromolecules}, number = {4}, pages = {2956--2965}, publisher = {American Chemical Society}, title = {{Supramolecular assembly of collagen-mimetic eptide D-periodic fibrils and nanoassemblies}}, doi = {10.1021/acs.biomac.6c00345}, volume = {27}, year = {2026}, } @article{21750, abstract = {Liquid-like superionic conductors, with highly mobile ions in a rigid framework, offer intrinsically low lattice thermal conductivity without compromising electronic transport. Argyrodite-type Ag8SnSe6 exhibits a melt-like Ag sublattice that drives lattice thermal conductivity (κL) below 0.2 watts per meter per kelvin, yet its low carrier concentration limits the power factor. Here, interstitial Ag atoms raise the Fermi level into the conduction band, substantially increasing the electron concentration. Simultaneously, the formation of a secondary Ag2Se phase generates lattice distortions that enhance phonon scattering. A pronounced mismatch between electronic (~200 nanometers) and phononic (~0.22 nanometers) mean free paths decouples charge and heat transport, enabling concurrent suppression of κL and retention of high electrical conductivity. This coupled electronic-phononic modulation yields a record ZT of 0.72 at ambient temperature and a peak ZT of 1.1 at 735 kelvins, with an average ZTavg of 0.72 over 320 to 735 kelvins. A unicouple device achieves 6.3% efficiency under a 357-kelvin gradient, highlighting a practical strategy for high-performance midtemperature thermoelectrics.}, author = {Li, Mengyao and Zhao, Xueke and Zhang, Yu and Yu, Jing and Liu, Xuyang and Jia, Mochen and Song, Hongzhang and Wang, Dongyang and Arbiol, Jordi and Ibáñez, Maria and Shan, Chongxin and Cabot, Andreu and Wang, Ziyu}, issn = {2375-2548}, journal = {Science Advances}, number = {15}, publisher = {AAAS}, title = {{Electronic-phononic decoupling and Fermi-level tuning enable high thermoelectric performance in Ag8SnSe6}}, doi = {10.1126/sciadv.aec9073}, volume = {12}, year = {2026}, } @article{21752, abstract = {Epithelial tissues function as multicellular communities that preserve tissue integrity while adapting to diverse environmental stresses by altering cell behaviors. A striking manifestation of such adaptability is cell plasticity, the ability of differentiated cells to revert to stem-like states or adopt alternative fates. Once considered rare and confined to highly regenerative species, cell plasticity is now recognized across the metazoan tree. In early-branching animals such as sponges and cnidarians, transdifferentiation and dedifferentiation are integral to life-cycle transitions and regeneration, whereas in more complex organisms, these processes typically emerge under stress, including stem cell loss or environmental perturbations. Here, we examine epithelial cell plasticity through evolutionary, cellular, and molecular perspectives. Focusing on the intestinal epithelium, we explore findings from mammalian and Drosophila models showing that progenitors and even terminally differentiated cells can dedifferentiate in response to external stimuli that disrupt homeostasis, such as pathogen infection and nutrient fluctuations. We further discuss conserved mechanisms involving intercellular signaling (e.g., Notch, EGFR, and JAK-STAT) and chromatin states primed for reprogramming, modulated by metabolic cues. Together, these insights position cell plasticity as an ancient environmental adaptation strategy, shaped by conserved molecular toolkits and refined by species- and cell lineage-specific innovations.}, author = {Nagai, Hiroki and Nakajima, Yu Ichiro}, issn = {1096-3634}, journal = {Seminars in Cell and Developmental Biology}, publisher = {Elsevier}, title = {{Epithelial cell plasticity in metazoans: Evolutionary insights into roles and mechanisms}}, doi = {10.1016/j.semcdb.2026.103670}, volume = {179-180}, year = {2026}, } @article{21755, abstract = {Tropical shallow clouds are a major source of uncertainty in Earth's climate sensitivity, especially through their spatial arrangement, which global climate models do not represent. Efforts to understand their organization have partly relied on classifying observed scenes, identifying four patterns as archetypal regimes. Here we analyze geostationary satellite imagery of the western tropical Atlantic using the L‐function, a tool based on point pattern theory that quantifies cloud organization across spatial scales. Classical examples of the four patterns show distinct L‐function fingerprints, revealing their characteristic clustering and regularity scales and aiding physical interpretation. Yet, when evaluating many scenes at fixed spatial scales, the L‐function distribution lacks the distinct modes expected from discrete regimes. This is corroborated by analyses of other organization indices employing diverse approaches, from inter‐cloud nearest‐neighbor distances to fractal analysis. Implications for the parameterization of mesoscale cloud organization in climate models are discussed.}, author = {Biagioli, Giovanni and Mandorli, Giulio and Freischem, Lilli Johanna and Casallas Garcia, Alejandro and Tompkins, Adrian Mark}, issn = {1944-8007}, journal = {Geophysical Research Letters}, number = {8}, publisher = {Wiley}, title = {{Spatial patterns of shallow clouds: Challenging the concept of defined regimes}}, doi = {10.1029/2025gl119921}, volume = {53}, year = {2026}, } @article{21760, abstract = {3I/ATLAS is the third interstellar object discovered to date, following 1I/‘Oumuamua and 2I/Borisov. Its unusually high excess velocity and active cometary nature make it a key probe of the Galactic population of icy planetesimals. Understanding its origin requires its past trajectory through the Galaxy to be traced and the possible role of stellar encounters to be assessed, both as a potential origin and a perturber to its orbit. We integrated the orbit of 3I/ATLAS backward in time for 10 Myr, together with a sample of Gaia DR3 stars with high-quality astrometry and radial velocities, to identify close passages within 2 pc. We identify 93 nominal encounters, 62 of which are significant at the 2σ level. However, none of these encounters produced any meaningful perturbation. The strongest perturber Gaia DR3 6863591389529611264 at 0.30 pc and with a relative velocity of 35 km s−1, imparted only a velocity change of ∣Δv∣ ≃ 5 × 10−4 km s−1 to the orbit of 3I/ATLAS. Our results indicate that no stellar flybys within the past 10 Myr and 500 pc contained in Gaia DR3 can account for the present trajectory of 3I/ATLAS or be associated with its origin. We further show that 3I/ATLAS is kinematically consistent with a thin-disk population, despite its large peculiar velocity.}, author = {Pérez-Couto, X. and Torres Rodriguez, Santiago and Villaver, E. and Mustill, A. J. and Manteiga, M.}, issn = {1538-4357}, journal = {The Astrophysical Journal}, number = {2}, publisher = {IOP Publishing}, title = {{3I/ATLAS: In search of the witnesses to its voyage}}, doi = {10.3847/1538-4357/ae56ff}, volume = {1001}, year = {2026}, }