[{"doi":"10.1137/1.9781611977929.17","project":[{"_id":"bd9ca328-d553-11ed-ba76-dc4f890cfe62","name":"The design and evaluation of modern fully dynamic data structures","grant_number":"101019564","call_identifier":"H2020"},{"grant_number":"Z00422","name":"Efficient algorithms","_id":"34def286-11ca-11ed-8bc3-da5948e1613c"},{"grant_number":"I05982","name":"Static and Dynamic Hierarchical Graph Decompositions","_id":"bda196b2-d553-11ed-ba76-8e8ee6c21103"},{"_id":"bd9e3a2e-d553-11ed-ba76-8aa684ce17fe","grant_number":"P33775","name":"Fast Algorithms for a Reactive Network Layer"},{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020"}],"month":"01","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2310.18034"}],"ec_funded":1,"corr_author":"1","day":"04","status":"public","arxiv":1,"publication_identifier":{"eisbn":["9781611977929"]},"publication":"2024 Proceedings of the Symposium on Algorithm Engineering and Experiments","publisher":"Society for Industrial and Applied Mathematics","publication_status":"published","quality_controlled":"1","external_id":{"arxiv":["2310.18034"]},"acknowledgement":"This   project   has   received   funding   from   the   Euro-pean  Research  Council  (ERC)  under  the  EuropeanUnion’s  Horizon  2020  research  and  innovation  programme  (Grant  agreement  No.   101019564  “The  De-sign  of  Modern  Fully  Dynamic  Data  Structures  (Mo-DynStruct)”  and  the  Austrian  Science  Fund  (FWF)project Z 422-N, project “Static and Dynamic Hierar-chical  Graph  Decompositions”,  I  5982-N,  and  project“Fast  Algorithms  for  a  Reactive  Network  Layer  (Re-actNet)”, P 33775-N, with additional funding from thenetidee SCIENCE Stiftung, 2020–2024.D.  Sauplic  has  received  funding  from  the  Euro-pean  Union’s  Horizon  2020  research  and  innovation programme under the Marie Sklodowska-Curie    grant    agreementNo 101034413.","citation":{"mla":"Henzinger, Monika, et al. “Experimental Evaluation of Fully Dynamic K-Means via Coresets.” <i>2024 Proceedings of the Symposium on Algorithm Engineering and Experiments</i>, Society for Industrial and Applied Mathematics, 2024, pp. 220–33, doi:<a href=\"https://doi.org/10.1137/1.9781611977929.17\">10.1137/1.9781611977929.17</a>.","short":"M. Henzinger, D. Saulpic, L. Sidl, in:, 2024 Proceedings of the Symposium on Algorithm Engineering and Experiments, Society for Industrial and Applied Mathematics, 2024, pp. 220–233.","apa":"Henzinger, M., Saulpic, D., &#38; Sidl, L. (2024). Experimental evaluation of fully dynamic k-means via coresets. In <i>2024 Proceedings of the Symposium on Algorithm Engineering and Experiments</i> (pp. 220–233). Alexandria, VA, United States: Society for Industrial and Applied Mathematics. <a href=\"https://doi.org/10.1137/1.9781611977929.17\">https://doi.org/10.1137/1.9781611977929.17</a>","ista":"Henzinger M, Saulpic D, Sidl L. 2024. Experimental evaluation of fully dynamic k-means via coresets. 2024 Proceedings of the Symposium on Algorithm Engineering and Experiments. ALENEX: Workshop on Algorithm Engineering and Experiments, 220–233.","chicago":"Henzinger, Monika, David Saulpic, and Leonhard Sidl. “Experimental Evaluation of Fully Dynamic K-Means via Coresets.” In <i>2024 Proceedings of the Symposium on Algorithm Engineering and Experiments</i>, 220–33. Society for Industrial and Applied Mathematics, 2024. <a href=\"https://doi.org/10.1137/1.9781611977929.17\">https://doi.org/10.1137/1.9781611977929.17</a>.","ama":"Henzinger M, Saulpic D, Sidl L. Experimental evaluation of fully dynamic k-means via coresets. In: <i>2024 Proceedings of the Symposium on Algorithm Engineering and Experiments</i>. Society for Industrial and Applied Mathematics; 2024:220-233. doi:<a href=\"https://doi.org/10.1137/1.9781611977929.17\">10.1137/1.9781611977929.17</a>","ieee":"M. Henzinger, D. Saulpic, and L. Sidl, “Experimental evaluation of fully dynamic k-means via coresets,” in <i>2024 Proceedings of the Symposium on Algorithm Engineering and Experiments</i>, Alexandria, VA, United States, 2024, pp. 220–233."},"date_published":"2024-01-04T00:00:00Z","department":[{"_id":"MoHe"}],"page":"220-233","_id":"14769","date_updated":"2025-04-14T13:50:50Z","abstract":[{"text":"For a set of points in Rd, the Euclidean k-means problems consists of finding k centers such that the sum of distances squared from each data point to its closest center is minimized. Coresets are one the main tools developed recently to solve this problem in a big data context. They allow to compress the initial dataset while preserving its structure: running any algorithm on the coreset provides a guarantee almost equivalent to running it on the full data. In this work, we study coresets in a fully-dynamic setting: points are added and deleted with the goal to efficiently maintain a coreset with which a k-means solution can be computed. Based on an algorithm from Henzinger and Kale [ESA'20], we present an efficient and practical implementation of a fully dynamic coreset algorithm, that improves the running time by up to a factor of 20 compared to our non-optimized implementation of the algorithm by Henzinger and Kale, without sacrificing more than 7% on the quality of the k-means solution.","lang":"eng"}],"language":[{"iso":"eng"}],"oa":1,"oa_version":"Preprint","date_created":"2024-01-09T16:22:47Z","type":"conference","conference":{"location":"Alexandria, VA, United States","start_date":"2024-01-07","name":"ALENEX: Workshop on Algorithm Engineering and Experiments","end_date":"2024-01-08"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Experimental evaluation of fully dynamic k-means via coresets","scopus_import":"1","author":[{"first_name":"Monika H","orcid":"0000-0002-5008-6530","last_name":"Henzinger","id":"540c9bbd-f2de-11ec-812d-d04a5be85630","full_name":"Henzinger, Monika H"},{"first_name":"David","last_name":"Saulpic","id":"f8e48cf0-b0ff-11ed-b0e9-b4c35598f964","full_name":"Saulpic, David"},{"id":"8b563fd0-b441-11ee-9101-a3891c61efa6","full_name":"Sidl, Leonhard","last_name":"Sidl","first_name":"Leonhard"}],"year":"2024","article_processing_charge":"No"},{"project":[{"grant_number":"24812","name":"Molecular mechanisms of radial neuronal migration","_id":"2625A13E-B435-11E9-9278-68D0E5697425"}],"file_date_updated":"2024-07-16T12:04:46Z","doi":"10.1016/j.xpro.2023.102795","month":"03","corr_author":"1","publication_identifier":{"eissn":["2666-1667"]},"file":[{"success":1,"access_level":"open_access","file_name":"2024_STARProtoc_Hansen.pdf","file_size":3758943,"checksum":"4644d537451c5c114a9d7c7829b65bba","content_type":"application/pdf","date_updated":"2024-07-16T12:04:46Z","creator":"dernst","file_id":"17264","relation":"main_file","date_created":"2024-07-16T12:04:46Z"}],"status":"public","day":"15","pmid":1,"publication_status":"published","publisher":"Elsevier","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"volume":5,"publication":"STAR Protocols","acknowledgement":"We thank Florian Pauler for discussion and his expert technical support. This research was supported by the Scientific Service Units (SSU) at IST Austria through resources provided by the Imaging and Optics Facility (IOF) and Preclinical Facility (PCF). A.H.H. was a recipient of a DOC Fellowship (24812) of the Austrian Academy of Sciences.","external_id":{"pmid":["38165800"]},"ddc":["570"],"quality_controlled":"1","acknowledged_ssus":[{"_id":"Bio"},{"_id":"PreCl"}],"language":[{"iso":"eng"}],"has_accepted_license":"1","_id":"14794","date_updated":"2025-04-15T07:32:40Z","abstract":[{"lang":"eng","text":"Mosaic analysis with double markers (MADM) technology enables the sparse labeling of genetically defined neurons. We present a protocol for time-lapse imaging of cortical projection neuron migration in mice using MADM. We describe steps for the isolation, culturing, and 4D imaging of neuronal dynamics in MADM-labeled brain tissue. While this protocol is compatible with other single-cell labeling methods, the MADM approach provides a genetic platform for the functional assessment of cell-autonomous candidate gene function and the relative contribution of non-cell-autonomous effects.\r\n\r\nFor complete details on the use and execution of this protocol, please refer to Hansen et al. (2022),1 Contreras et al. (2021),2 and Amberg and Hippenmeyer (2021).3"}],"date_published":"2024-03-15T00:00:00Z","department":[{"_id":"SiHi"}],"citation":{"mla":"Hansen, Andi H., and Simon Hippenmeyer. “Time-Lapse Imaging of Cortical Projection Neuron Migration in Mice Using Mosaic Analysis with Double Markers.” <i>STAR Protocols</i>, vol. 5, no. 1, 102795, Elsevier, 2024, doi:<a href=\"https://doi.org/10.1016/j.xpro.2023.102795\">10.1016/j.xpro.2023.102795</a>.","short":"A.H. Hansen, S. Hippenmeyer, STAR Protocols 5 (2024).","apa":"Hansen, A. H., &#38; Hippenmeyer, S. (2024). Time-lapse imaging of cortical projection neuron migration in mice using mosaic analysis with double markers. <i>STAR Protocols</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.xpro.2023.102795\">https://doi.org/10.1016/j.xpro.2023.102795</a>","ista":"Hansen AH, Hippenmeyer S. 2024. Time-lapse imaging of cortical projection neuron migration in mice using mosaic analysis with double markers. STAR Protocols. 5(1), 102795.","chicago":"Hansen, Andi H, and Simon Hippenmeyer. “Time-Lapse Imaging of Cortical Projection Neuron Migration in Mice Using Mosaic Analysis with Double Markers.” <i>STAR Protocols</i>. Elsevier, 2024. <a href=\"https://doi.org/10.1016/j.xpro.2023.102795\">https://doi.org/10.1016/j.xpro.2023.102795</a>.","ieee":"A. H. Hansen and S. Hippenmeyer, “Time-lapse imaging of cortical projection neuron migration in mice using mosaic analysis with double markers,” <i>STAR Protocols</i>, vol. 5, no. 1. Elsevier, 2024.","ama":"Hansen AH, Hippenmeyer S. Time-lapse imaging of cortical projection neuron migration in mice using mosaic analysis with double markers. <i>STAR Protocols</i>. 2024;5(1). doi:<a href=\"https://doi.org/10.1016/j.xpro.2023.102795\">10.1016/j.xpro.2023.102795</a>"},"oa":1,"issue":"1","article_number":"102795","type":"journal_article","oa_version":"Published Version","date_created":"2024-01-14T23:00:56Z","scopus_import":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Time-lapse imaging of cortical projection neuron migration in mice using mosaic analysis with double markers","article_type":"review","related_material":{"link":[{"relation":"software","url":"http://github.com/hippenmeyerlab"}]},"intvolume":"         5","author":[{"id":"38853E16-F248-11E8-B48F-1D18A9856A87","full_name":"Hansen, Andi H","first_name":"Andi H","last_name":"Hansen"},{"full_name":"Hippenmeyer, Simon","id":"37B36620-F248-11E8-B48F-1D18A9856A87","last_name":"Hippenmeyer","orcid":"0000-0003-2279-1061","first_name":"Simon"}],"article_processing_charge":"Yes","year":"2024"},{"page":"171-182.e8","date_published":"2024-01-08T00:00:00Z","citation":{"mla":"Arslan, Feyza N., et al. “Adhesion-Induced Cortical Flows Pattern E-Cadherin-Mediated Cell Contacts.” <i>Current Biology</i>, vol. 34, no. 1, Elsevier, 2024, p. 171–182.e8, doi:<a href=\"https://doi.org/10.1016/j.cub.2023.11.067\">10.1016/j.cub.2023.11.067</a>.","short":"F.N. Arslan, E.B. Hannezo, J. Merrin, M. Loose, C.-P.J. Heisenberg, Current Biology 34 (2024) 171–182.e8.","apa":"Arslan, F. N., Hannezo, E. B., Merrin, J., Loose, M., &#38; Heisenberg, C.-P. J. (2024). Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts. <i>Current Biology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.cub.2023.11.067\">https://doi.org/10.1016/j.cub.2023.11.067</a>","ama":"Arslan FN, Hannezo EB, Merrin J, Loose M, Heisenberg C-PJ. Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts. <i>Current Biology</i>. 2024;34(1):171-182.e8. doi:<a href=\"https://doi.org/10.1016/j.cub.2023.11.067\">10.1016/j.cub.2023.11.067</a>","ieee":"F. N. Arslan, E. B. Hannezo, J. Merrin, M. Loose, and C.-P. J. Heisenberg, “Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts,” <i>Current Biology</i>, vol. 34, no. 1. Elsevier, p. 171–182.e8, 2024.","ista":"Arslan FN, Hannezo EB, Merrin J, Loose M, Heisenberg C-PJ. 2024. Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts. Current Biology. 34(1), 171–182.e8.","chicago":"Arslan, Feyza N, Edouard B Hannezo, Jack Merrin, Martin Loose, and Carl-Philipp J Heisenberg. “Adhesion-Induced Cortical Flows Pattern E-Cadherin-Mediated Cell Contacts.” <i>Current Biology</i>. Elsevier, 2024. <a href=\"https://doi.org/10.1016/j.cub.2023.11.067\">https://doi.org/10.1016/j.cub.2023.11.067</a>."},"department":[{"_id":"CaHe"},{"_id":"EdHa"},{"_id":"MaLo"},{"_id":"NanoFab"}],"_id":"14795","abstract":[{"lang":"eng","text":"Metazoan development relies on the formation and remodeling of cell-cell contacts. Dynamic reorganization of adhesion receptors and the actomyosin cell cortex in space and time plays a central role in cell-cell contact formation and maturation. Nevertheless, how this process is mechanistically achieved when new contacts are formed remains unclear. Here, by building a biomimetic assay composed of progenitor cells adhering to supported lipid bilayers functionalized with E-cadherin ectodomains, we show that cortical F-actin flows, driven by the depletion of myosin-2 at the cell contact center, mediate the dynamic reorganization of adhesion receptors and cell cortex at the contact. E-cadherin-dependent downregulation of the small GTPase RhoA at the forming contact leads to both a depletion of myosin-2 and a decrease of F-actin at the contact center. At the contact rim, in contrast, myosin-2 becomes enriched by the retraction of bleb-like protrusions, resulting in a cortical tension gradient from the contact rim to its center. This tension gradient, in turn, triggers centrifugal F-actin flows, leading to further accumulation of F-actin at the contact rim and the progressive redistribution of E-cadherin from the contact center to the rim. Eventually, this combination of actomyosin downregulation and flows at the contact determines the characteristic molecular organization, with E-cadherin and F-actin accumulating at the contact rim, where they are needed to mechanically link the contractile cortices of the adhering cells."}],"date_updated":"2025-09-04T11:39:10Z","has_accepted_license":"1","acknowledged_ssus":[{"_id":"Bio"},{"_id":"PreCl"}],"language":[{"iso":"eng"}],"oa_version":"Published Version","date_created":"2024-01-14T23:00:56Z","type":"journal_article","issue":"1","isi":1,"oa":1,"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts","scopus_import":"1","year":"2024","article_processing_charge":"Yes (via OA deal)","author":[{"id":"49DA7910-F248-11E8-B48F-1D18A9856A87","full_name":"Arslan, Feyza N","first_name":"Feyza N","last_name":"Arslan","orcid":"0000-0001-5809-9566"},{"first_name":"Edouard B","last_name":"Hannezo","orcid":"0000-0001-6005-1561","full_name":"Hannezo, Edouard B","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87"},{"orcid":"0000-0001-5145-4609","last_name":"Merrin","first_name":"Jack","full_name":"Merrin, Jack","id":"4515C308-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Martin","orcid":"0000-0001-7309-9724","last_name":"Loose","id":"462D4284-F248-11E8-B48F-1D18A9856A87","full_name":"Loose, Martin"},{"first_name":"Carl-Philipp J","orcid":"0000-0002-0912-4566","last_name":"Heisenberg","id":"39427864-F248-11E8-B48F-1D18A9856A87","full_name":"Heisenberg, Carl-Philipp J"}],"intvolume":"        34","article_type":"original","month":"01","doi":"10.1016/j.cub.2023.11.067","file_date_updated":"2024-01-16T10:53:31Z","project":[{"call_identifier":"H2020","grant_number":"742573","name":"Interaction and feedback between cell mechanics and fate specification in vertebrate gastrulation","_id":"260F1432-B435-11E9-9278-68D0E5697425"}],"corr_author":"1","ec_funded":1,"publication":"Current Biology","volume":34,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"publisher":"Elsevier","publication_status":"published","day":"08","pmid":1,"status":"public","file":[{"checksum":"51220b76d72a614208f84bdbfbaf9b72","content_type":"application/pdf","creator":"dernst","date_updated":"2024-01-16T10:53:31Z","success":1,"file_name":"2024_CurrentBiology_Arslan.pdf","access_level":"open_access","file_size":5183861,"date_created":"2024-01-16T10:53:31Z","relation":"main_file","file_id":"14813"}],"publication_identifier":{"issn":["0960-9822"],"eissn":["1879-0445"]},"quality_controlled":"1","ddc":["570"],"external_id":{"pmid":["38134934"],"isi":["001154500400001"]},"acknowledgement":"We are grateful to Edwin Munro for their feedback and help with the single particle analysis. We thank members of the Heisenberg and Loose labs for their help and feedback on the manuscript, notably Xin Tong for making the PCS2-mCherry-AHPH plasmid. Finally, we thank the Aquatics and Imaging & Optics facilities of ISTA for their continuous support, especially Yann Cesbron for assistance with the laser cutter. This work was supported by an ERC\r\nAdvanced Grant (MECSPEC) to C.-P.H."},{"title":"Annealed quantitative estimates for the quadratic 2D-discrete random matching problem","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","scopus_import":"1","article_processing_charge":"Yes (in subscription journal)","year":"2024","intvolume":"       190","author":[{"id":"fea1b376-906f-11eb-847d-b2c0cf46455b","full_name":"Clozeau, Nicolas","first_name":"Nicolas","last_name":"Clozeau"},{"last_name":"Mattesini","first_name":"Francesco","full_name":"Mattesini, Francesco"}],"article_type":"original","abstract":[{"lang":"eng","text":"We study a random matching problem on closed compact  2 -dimensional Riemannian manifolds (with respect to the squared Riemannian distance), with samples of random points whose common law is absolutely continuous with respect to the volume measure with strictly positive and bounded density. We show that given two sequences of numbers  n  and  m=m(n)  of points, asymptotically equivalent as  n  goes to infinity, the optimal transport plan between the two empirical measures  μn  and  νm  is quantitatively well-approximated by  (Id,exp(∇hn))#μn  where  hn  solves a linear elliptic PDE obtained by a regularized first-order linearization of the Monge-Ampère equation. This is obtained in the case of samples of correlated random points for which a stretched exponential decay of the  α -mixing coefficient holds and for a class of discrete-time Markov chains having a unique absolutely continuous invariant measure with respect to the volume measure."}],"_id":"14797","date_updated":"2025-09-04T11:43:43Z","date_published":"2024-10-01T00:00:00Z","page":"485-541","citation":{"apa":"Clozeau, N., &#38; Mattesini, F. (2024). Annealed quantitative estimates for the quadratic 2D-discrete random matching problem. <i>Probability Theory and Related Fields</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00440-023-01254-0\">https://doi.org/10.1007/s00440-023-01254-0</a>","short":"N. Clozeau, F. Mattesini, Probability Theory and Related Fields 190 (2024) 485–541.","mla":"Clozeau, Nicolas, and Francesco Mattesini. “Annealed Quantitative Estimates for the Quadratic 2D-Discrete Random Matching Problem.” <i>Probability Theory and Related Fields</i>, vol. 190, Springer Nature, 2024, pp. 485–541, doi:<a href=\"https://doi.org/10.1007/s00440-023-01254-0\">10.1007/s00440-023-01254-0</a>.","ama":"Clozeau N, Mattesini F. Annealed quantitative estimates for the quadratic 2D-discrete random matching problem. <i>Probability Theory and Related Fields</i>. 2024;190:485-541. doi:<a href=\"https://doi.org/10.1007/s00440-023-01254-0\">10.1007/s00440-023-01254-0</a>","ieee":"N. Clozeau and F. Mattesini, “Annealed quantitative estimates for the quadratic 2D-discrete random matching problem,” <i>Probability Theory and Related Fields</i>, vol. 190. Springer Nature, pp. 485–541, 2024.","chicago":"Clozeau, Nicolas, and Francesco Mattesini. “Annealed Quantitative Estimates for the Quadratic 2D-Discrete Random Matching Problem.” <i>Probability Theory and Related Fields</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1007/s00440-023-01254-0\">https://doi.org/10.1007/s00440-023-01254-0</a>.","ista":"Clozeau N, Mattesini F. 2024. Annealed quantitative estimates for the quadratic 2D-discrete random matching problem. Probability Theory and Related Fields. 190, 485–541."},"department":[{"_id":"JuFi"}],"language":[{"iso":"eng"}],"has_accepted_license":"1","date_created":"2024-01-14T23:00:57Z","oa_version":"Published Version","type":"journal_article","oa":1,"isi":1,"volume":190,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"publication":"Probability Theory and Related Fields","publication_status":"published","publisher":"Springer Nature","status":"public","day":"01","publication_identifier":{"issn":["0178-8051"],"eissn":["1432-2064"]},"file":[{"creator":"dernst","date_updated":"2025-01-09T08:10:54Z","checksum":"34f44cad6a210ff66791ee37e590af2c","content_type":"application/pdf","file_size":880117,"success":1,"access_level":"open_access","file_name":"2024_ProbTheoryRelatFields_Clozeau.pdf","date_created":"2025-01-09T08:10:54Z","relation":"main_file","file_id":"18788"}],"arxiv":1,"quality_controlled":"1","acknowledgement":"NC has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (Grant agreement No 948819).\r\nFM is supported by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) through the SPP 2265 Random Geometric Systems. FM has been funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy EXC 2044 -390685587, Mathematics Münster: Dynamics–Geometry–Structure. FM has been funded by the Max Planck Institute for Mathematics in the Sciences.","external_id":{"arxiv":["2303.00353"],"isi":["001136206200002"]},"ddc":["510"],"month":"10","file_date_updated":"2025-01-09T08:10:54Z","doi":"10.1007/s00440-023-01254-0","project":[{"_id":"0aa76401-070f-11eb-9043-b5bb049fa26d","name":"Bridging Scales in Random Materials","grant_number":"948819","call_identifier":"H2020"}],"OA_type":"hybrid","OA_place":"publisher","corr_author":"1","ec_funded":1},{"year":"2024","keyword":["Atomic and Molecular Physics","and Optics","Electronic","Optical and Magnetic Materials"],"article_processing_charge":"Yes","article_type":"original","intvolume":"        11","author":[{"first_name":"Fritz R","last_name":"Diorico","orcid":"0000-0002-4947-8924","id":"2E054C4C-F248-11E8-B48F-1D18A9856A87","full_name":"Diorico, Fritz R"},{"full_name":"Zhutov, Artem","id":"0f02ed6a-b514-11ee-b891-8379c5f19cb7","first_name":"Artem","last_name":"Zhutov"},{"orcid":"0000-0002-2031-204X","last_name":"Hosten","first_name":"Onur","full_name":"Hosten, Onur","id":"4C02D85E-F248-11E8-B48F-1D18A9856A87"}],"scopus_import":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"Laser-cavity locking utilizing beam ellipticity: accessing the 10<sup>−7</sup> instability scale relative to cavity linewidth","type":"journal_article","date_created":"2024-01-15T10:25:38Z","oa_version":"Published Version","isi":1,"oa":1,"issue":"1","has_accepted_license":"1","language":[{"iso":"eng"}],"page":"26-31","date_published":"2024-01-20T00:00:00Z","citation":{"chicago":"Diorico, Fritz R, Artem Zhutov, and Onur Hosten. “Laser-Cavity Locking Utilizing Beam Ellipticity: Accessing the 10<sup>−7</sup> Instability Scale Relative to Cavity Linewidth.” <i>Optica</i>. Optica Publishing Group, 2024. <a href=\"https://doi.org/10.1364/optica.507451\">https://doi.org/10.1364/optica.507451</a>.","ista":"Diorico FR, Zhutov A, Hosten O. 2024. Laser-cavity locking utilizing beam ellipticity: accessing the 10<sup>−7</sup> instability scale relative to cavity linewidth. Optica. 11(1), 26–31.","ieee":"F. R. Diorico, A. Zhutov, and O. Hosten, “Laser-cavity locking utilizing beam ellipticity: accessing the 10<sup>−7</sup> instability scale relative to cavity linewidth,” <i>Optica</i>, vol. 11, no. 1. Optica Publishing Group, pp. 26–31, 2024.","ama":"Diorico FR, Zhutov A, Hosten O. Laser-cavity locking utilizing beam ellipticity: accessing the 10<sup>−7</sup> instability scale relative to cavity linewidth. <i>Optica</i>. 2024;11(1):26-31. doi:<a href=\"https://doi.org/10.1364/optica.507451\">10.1364/optica.507451</a>","apa":"Diorico, F. R., Zhutov, A., &#38; Hosten, O. (2024). Laser-cavity locking utilizing beam ellipticity: accessing the 10<sup>−7</sup> instability scale relative to cavity linewidth. <i>Optica</i>. Optica Publishing Group. <a href=\"https://doi.org/10.1364/optica.507451\">https://doi.org/10.1364/optica.507451</a>","short":"F.R. Diorico, A. Zhutov, O. Hosten, Optica 11 (2024) 26–31.","mla":"Diorico, Fritz R., et al. “Laser-Cavity Locking Utilizing Beam Ellipticity: Accessing the 10<sup>−7</sup> Instability Scale Relative to Cavity Linewidth.” <i>Optica</i>, vol. 11, no. 1, Optica Publishing Group, 2024, pp. 26–31, doi:<a href=\"https://doi.org/10.1364/optica.507451\">10.1364/optica.507451</a>."},"department":[{"_id":"OnHo"}],"_id":"14802","DOAJ_listed":"1","date_updated":"2025-09-04T12:13:27Z","abstract":[{"lang":"eng","text":"Frequency-stable lasers form the back bone of precision measurements in science and technology. Such lasers typically attain their stability through frequency locking to reference cavities. State-of-the-art locking performances to date had been achieved using frequency modulation based methods, complemented with active drift cancellation systems. We demonstrate an all passive, modulation-free laser-cavity locking technique (squash locking) that utilizes changes in spatial beam ellipticity for error signal generation, and a coherent polarization post-selection for noise resilience. By comparing two identically built proof-of-principle systems, we show a frequency locking instability of 5×10<jats:sup>−7</jats:sup> relative to the cavity linewidth at 10 s averaging. The results surpass the demonstrated performances of methods engineered over the last five decades, potentially enabling an advancement in the precision control of lasers, while creating avenues for bridging the performance gaps between industrial grade lasers with scientific ones due to the afforded simplicity and scalability."}],"APC_amount":"3393,38 EUR","external_id":{"isi":["001202817000004"]},"ddc":["530"],"acknowledgement":"We thank Rishabh Sahu and Sebastian Wald for technical contributions to the experiment. Funding by Institute of Science and Technology Austria.","quality_controlled":"1","publisher":"Optica Publishing Group","publication_status":"published","publication":"Optica","volume":11,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"file":[{"file_id":"14824","date_created":"2024-01-17T08:53:16Z","relation":"main_file","success":1,"access_level":"open_access","file_name":"2023_Optica_Diorico.pdf","file_size":4558986,"checksum":"eb99ca7d0fe73e22f121875175546ed7","content_type":"application/pdf","creator":"dernst","date_updated":"2024-01-17T08:53:16Z"}],"publication_identifier":{"issn":["2334-2536"]},"day":"20","status":"public","OA_place":"publisher","corr_author":"1","month":"01","OA_type":"gold","doi":"10.1364/optica.507451","file_date_updated":"2024-01-17T08:53:16Z"},{"ddc":["000"],"external_id":{"isi":["001168211400001"]},"acknowledgement":"We thank Mahsa Bastankhah and Mohammad Ali Maddah-Ali for fruitful discussions about different variants of the problem. This work is supported by the European Research Council (ERC) Consolidator Project 864228 (AdjustNet), 2020-2025, the ERC CoG 863818 (ForM-SMArt), and the German Research Foundation (DFG) grant 470029389 (FlexNets), 2021-2024.","quality_controlled":"1","publisher":"Elsevier","publication_status":"published","publication":"Theoretical Computer Science","volume":989,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"file":[{"checksum":"efd5b7e738bf845312ba53889a3e13e4","content_type":"application/pdf","date_updated":"2024-07-16T12:02:25Z","creator":"dernst","success":1,"access_level":"open_access","file_name":"2024_TheorComputerScience_Schmid.pdf","file_size":603570,"date_created":"2024-07-16T12:02:25Z","relation":"main_file","file_id":"17263"}],"publication_identifier":{"issn":["0304-3975"]},"day":"21","status":"public","corr_author":"1","ec_funded":1,"month":"03","project":[{"_id":"0599E47C-7A3F-11EA-A408-12923DDC885E","name":"Formal Methods for Stochastic Models: Algorithms and Applications","grant_number":"863818","call_identifier":"H2020"}],"doi":"10.1016/j.tcs.2023.114353","file_date_updated":"2024-07-16T12:02:25Z","year":"2024","keyword":["General Computer Science","Theoretical Computer Science"],"article_processing_charge":"Yes (via OA deal)","related_material":{"record":[{"id":"19985","status":"public","relation":"earlier_version"}]},"article_type":"original","intvolume":"       989","author":[{"last_name":"Schmid","first_name":"Stefan","full_name":"Schmid, Stefan"},{"full_name":"Svoboda, Jakub","id":"130759D2-D7DD-11E9-87D2-DE0DE6697425","orcid":"0000-0002-1419-3267","last_name":"Svoboda","first_name":"Jakub"},{"full_name":"Yeo, Michelle X","id":"2D82B818-F248-11E8-B48F-1D18A9856A87","orcid":"0009-0001-3676-4809","last_name":"Yeo","first_name":"Michelle X"}],"scopus_import":"1","title":"Weighted packet selection for rechargeable links in cryptocurrency networks: Complexity and approximation","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","type":"journal_article","article_number":"114353","date_created":"2024-01-16T13:40:41Z","oa_version":"Published Version","isi":1,"oa":1,"has_accepted_license":"1","language":[{"iso":"eng"}],"citation":{"apa":"Schmid, S., Svoboda, J., &#38; Yeo, M. X. (2024). Weighted packet selection for rechargeable links in cryptocurrency networks: Complexity and approximation. <i>Theoretical Computer Science</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.tcs.2023.114353\">https://doi.org/10.1016/j.tcs.2023.114353</a>","mla":"Schmid, Stefan, et al. “Weighted Packet Selection for Rechargeable Links in Cryptocurrency Networks: Complexity and Approximation.” <i>Theoretical Computer Science</i>, vol. 989, 114353, Elsevier, 2024, doi:<a href=\"https://doi.org/10.1016/j.tcs.2023.114353\">10.1016/j.tcs.2023.114353</a>.","short":"S. Schmid, J. Svoboda, M.X. Yeo, Theoretical Computer Science 989 (2024).","ieee":"S. Schmid, J. Svoboda, and M. X. Yeo, “Weighted packet selection for rechargeable links in cryptocurrency networks: Complexity and approximation,” <i>Theoretical Computer Science</i>, vol. 989. Elsevier, 2024.","ama":"Schmid S, Svoboda J, Yeo MX. Weighted packet selection for rechargeable links in cryptocurrency networks: Complexity and approximation. <i>Theoretical Computer Science</i>. 2024;989. doi:<a href=\"https://doi.org/10.1016/j.tcs.2023.114353\">10.1016/j.tcs.2023.114353</a>","chicago":"Schmid, Stefan, Jakub Svoboda, and Michelle X Yeo. “Weighted Packet Selection for Rechargeable Links in Cryptocurrency Networks: Complexity and Approximation.” <i>Theoretical Computer Science</i>. Elsevier, 2024. <a href=\"https://doi.org/10.1016/j.tcs.2023.114353\">https://doi.org/10.1016/j.tcs.2023.114353</a>.","ista":"Schmid S, Svoboda J, Yeo MX. 2024. Weighted packet selection for rechargeable links in cryptocurrency networks: Complexity and approximation. Theoretical Computer Science. 989, 114353."},"department":[{"_id":"KrCh"},{"_id":"KrPi"}],"date_published":"2024-03-21T00:00:00Z","_id":"14820","abstract":[{"lang":"eng","text":"We consider a natural problem dealing with weighted packet selection across a rechargeable link, which e.g., finds applications in cryptocurrency networks. The capacity of a link (u, v) is determined by how many nodes u and v allocate for this link. Specifically, the input is a finite ordered sequence of packets that arrive in both directions along a link. Given (u, v) and a packet of weight x going from u to v, node u can either accept or reject the packet. If u accepts the packet, the capacity on link (u, v) decreases by x. Correspondingly, v's capacity on \r\n increases by x. If a node rejects the packet, this will entail a cost affinely linear in the weight of the packet. A link is “rechargeable” in the sense that the total capacity of the link has to remain constant, but the allocation of capacity at the ends of the link can depend arbitrarily on the nodes' decisions. The goal is to minimise the sum of the capacity injected into the link and the cost of rejecting packets. We show that the problem is NP-hard, but can be approximated efficiently with a ratio of (1+E) . (1+3)  for some arbitrary E>0."}],"date_updated":"2025-12-02T14:02:37Z"},{"oa_version":"None","date_created":"2024-01-17T12:48:35Z","type":"journal_article","issue":"1","isi":1,"_id":"14828","date_updated":"2024-10-09T21:07:53Z","abstract":[{"text":"Production of hydrogen at large scale requires development of non-noble, inexpensive, and high-performing catalysts for constructing water-splitting devices. Herein, we report the synthesis of Zn-doped NiO heterostructure (ZnNiO) catalysts at room temperature via a coprecipitation method followed by drying (at 80 °C, 6 h) and calcination at an elevated temperature of 400 °C for 5 h under three distinct conditions, namely, air, N2, and vacuum. The vacuum-synthesized catalyst demonstrates a low overpotential of 88 mV at −10 mA cm–2 and a small Tafel slope of 73 mV dec–1 suggesting relatively higher charge transfer kinetics for hydrogen evolution reactions (HER) compared with the specimens synthesized under N2 or O2 atmosphere. It also demonstrates an oxygen evolution (OER) overpotential of 260 mV at 10 mA cm–2 with a low Tafel slope of 63 mV dec–1. In a full-cell water-splitting device, the vacuum-synthesized ZnNiO heterostructure demonstrates a cell voltage of 1.94 V at 50 mA cm–2 and shows remarkable stability over 24 h at a high current density of 100 mA cm–2. It is also demonstrated in this study that Zn-doping, surface, and interface engineering in transition-metal oxides play a crucial role in efficient electrocatalytic water splitting. Also, the results obtained from density functional theory (DFT + U = 0–8 eV), where U is the on-site Coulomb repulsion parameter also known as Hubbard U, based electronic structure calculations confirm that Zn doping constructively modifies the electronic structure, in both the valence band and the conduction band, and found to be suitable in tailoring the carrier’s effective masses of electrons and holes. The decrease in electron’s effective masses together with large differences between the effective masses of electrons and holes is noticed, which is found to be mainly responsible for achieving the best water-splitting performance from a 9% Zn-doped NiO sample prepared under vacuum.","lang":"eng"}],"date_published":"2024-01-08T00:00:00Z","page":"214-229","citation":{"ama":"Kiran GK, Singh S, Mahato N, et al. Interface engineering modulation combined with electronic structure modification of Zn-doped NiO heterostructure for efficient water-splitting activity. <i>ACS Applied Energy Materials</i>. 2024;7(1):214-229. doi:<a href=\"https://doi.org/10.1021/acsaem.3c02519\">10.1021/acsaem.3c02519</a>","ieee":"G. K. Kiran <i>et al.</i>, “Interface engineering modulation combined with electronic structure modification of Zn-doped NiO heterostructure for efficient water-splitting activity,” <i>ACS Applied Energy Materials</i>, vol. 7, no. 1. American Chemical Society, pp. 214–229, 2024.","ista":"Kiran GK, Singh S, Mahato N, Sreekanth TVM, Dillip GR, Yoo K, Kim J. 2024. Interface engineering modulation combined with electronic structure modification of Zn-doped NiO heterostructure for efficient water-splitting activity. ACS Applied Energy Materials. 7(1), 214–229.","chicago":"Kiran, Gundegowda Kalligowdanadoddi, Saurabh Singh, Neelima Mahato, Thupakula Venkata Madhukar Sreekanth, Gowra Raghupathy Dillip, Kisoo Yoo, and Jonghoon Kim. “Interface Engineering Modulation Combined with Electronic Structure Modification of Zn-Doped NiO Heterostructure for Efficient Water-Splitting Activity.” <i>ACS Applied Energy Materials</i>. American Chemical Society, 2024. <a href=\"https://doi.org/10.1021/acsaem.3c02519\">https://doi.org/10.1021/acsaem.3c02519</a>.","mla":"Kiran, Gundegowda Kalligowdanadoddi, et al. “Interface Engineering Modulation Combined with Electronic Structure Modification of Zn-Doped NiO Heterostructure for Efficient Water-Splitting Activity.” <i>ACS Applied Energy Materials</i>, vol. 7, no. 1, American Chemical Society, 2024, pp. 214–29, doi:<a href=\"https://doi.org/10.1021/acsaem.3c02519\">10.1021/acsaem.3c02519</a>.","short":"G.K. Kiran, S. Singh, N. Mahato, T.V.M. Sreekanth, G.R. Dillip, K. Yoo, J. Kim, ACS Applied Energy Materials 7 (2024) 214–229.","apa":"Kiran, G. K., Singh, S., Mahato, N., Sreekanth, T. V. M., Dillip, G. R., Yoo, K., &#38; Kim, J. (2024). Interface engineering modulation combined with electronic structure modification of Zn-doped NiO heterostructure for efficient water-splitting activity. <i>ACS Applied Energy Materials</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsaem.3c02519\">https://doi.org/10.1021/acsaem.3c02519</a>"},"department":[{"_id":"MaIb"}],"language":[{"iso":"eng"}],"article_processing_charge":"No","keyword":["Electrical and Electronic Engineering","Materials Chemistry","Electrochemistry","Energy Engineering and Power Technology","Chemical Engineering (miscellaneous)"],"year":"2024","intvolume":"         7","author":[{"full_name":"Kiran, Gundegowda Kalligowdanadoddi","first_name":"Gundegowda Kalligowdanadoddi","last_name":"Kiran"},{"full_name":"Singh, Saurabh","id":"12d625da-9cb3-11ed-9667-af09d37d3f0a","first_name":"Saurabh","last_name":"Singh","orcid":"0000-0003-2209-5269"},{"full_name":"Mahato, Neelima","first_name":"Neelima","last_name":"Mahato"},{"last_name":"Sreekanth","first_name":"Thupakula Venkata Madhukar","full_name":"Sreekanth, Thupakula Venkata Madhukar"},{"full_name":"Dillip, Gowra Raghupathy","first_name":"Gowra Raghupathy","last_name":"Dillip"},{"first_name":"Kisoo","last_name":"Yoo","full_name":"Yoo, Kisoo"},{"full_name":"Kim, Jonghoon","first_name":"Jonghoon","last_name":"Kim"}],"article_type":"original","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Interface engineering modulation combined with electronic structure modification of Zn-doped NiO heterostructure for efficient water-splitting activity","scopus_import":"1","corr_author":"1","month":"01","doi":"10.1021/acsaem.3c02519","quality_controlled":"1","acknowledgement":"This work was supported by the Technology Innovation Program (20011622, Development of Battery System Applied High-Efficiency Heat Control Polymer and Part Component) funded by the Ministry of Trade, Industry & Energy (MOTIE, Korea). Author acknowledge to Prof. Tsunehiro Takeuchi from Toyota Technological Institute, Nagoya, Japan for the support of computational resources.","external_id":{"isi":["001138342900001"]},"volume":7,"publication":"ACS Applied Energy Materials","publication_status":"published","publisher":"American Chemical Society","status":"public","day":"08","publication_identifier":{"issn":["2574-0962"]}},{"article_type":"review","author":[{"full_name":"Radler, Philipp","id":"40136C2A-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-9198-2182 ","last_name":"Radler","first_name":"Philipp"},{"orcid":"0000-0001-7309-9724","last_name":"Loose","first_name":"Martin","id":"462D4284-F248-11E8-B48F-1D18A9856A87","full_name":"Loose, Martin"}],"intvolume":"       103","keyword":["Cell Biology","General Medicine","Histology","Pathology and Forensic Medicine"],"year":"2024","article_processing_charge":"Yes","scopus_import":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"A dynamic duo: Understanding the roles of FtsZ and FtsA for Escherichia coli cell division through in vitro approaches","oa":1,"isi":1,"issue":"1","type":"journal_article","article_number":"151380","date_created":"2024-01-18T08:16:43Z","oa_version":"Published Version","has_accepted_license":"1","language":[{"iso":"eng"}],"citation":{"apa":"Radler, P., &#38; Loose, M. (2024). A dynamic duo: Understanding the roles of FtsZ and FtsA for Escherichia coli cell division through in vitro approaches. <i>European Journal of Cell Biology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.ejcb.2023.151380\">https://doi.org/10.1016/j.ejcb.2023.151380</a>","short":"P. Radler, M. Loose, European Journal of Cell Biology 103 (2024).","mla":"Radler, Philipp, and Martin Loose. “A Dynamic Duo: Understanding the Roles of FtsZ and FtsA for Escherichia Coli Cell Division through in Vitro Approaches.” <i>European Journal of Cell Biology</i>, vol. 103, no. 1, 151380, Elsevier, 2024, doi:<a href=\"https://doi.org/10.1016/j.ejcb.2023.151380\">10.1016/j.ejcb.2023.151380</a>.","ama":"Radler P, Loose M. A dynamic duo: Understanding the roles of FtsZ and FtsA for Escherichia coli cell division through in vitro approaches. <i>European Journal of Cell Biology</i>. 2024;103(1). doi:<a href=\"https://doi.org/10.1016/j.ejcb.2023.151380\">10.1016/j.ejcb.2023.151380</a>","ieee":"P. Radler and M. Loose, “A dynamic duo: Understanding the roles of FtsZ and FtsA for Escherichia coli cell division through in vitro approaches,” <i>European Journal of Cell Biology</i>, vol. 103, no. 1. Elsevier, 2024.","chicago":"Radler, Philipp, and Martin Loose. “A Dynamic Duo: Understanding the Roles of FtsZ and FtsA for Escherichia Coli Cell Division through in Vitro Approaches.” <i>European Journal of Cell Biology</i>. Elsevier, 2024. <a href=\"https://doi.org/10.1016/j.ejcb.2023.151380\">https://doi.org/10.1016/j.ejcb.2023.151380</a>.","ista":"Radler P, Loose M. 2024. A dynamic duo: Understanding the roles of FtsZ and FtsA for Escherichia coli cell division through in vitro approaches. European Journal of Cell Biology. 103(1), 151380."},"date_published":"2024-03-01T00:00:00Z","department":[{"_id":"MaLo"}],"_id":"14834","date_updated":"2025-09-04T11:45:31Z","abstract":[{"text":"Bacteria divide by binary fission. The protein machine responsible for this process is the divisome, a transient assembly of more than 30 proteins in and on the surface of the cytoplasmic membrane. Together, they constrict the cell envelope and remodel the peptidoglycan layer to eventually split the cell into two. For Escherichia coli, most molecular players involved in this process have probably been identified, but obtaining the quantitative information needed for a mechanistic understanding can often not be achieved from experiments in vivo alone. Since the discovery of the Z-ring more than 30 years ago, in vitro reconstitution experiments have been crucial to shed light on molecular processes normally hidden in the complex environment of the living cell. In this review, we summarize how rebuilding the divisome from purified components – or at least parts of it - have been instrumental to obtain the detailed mechanistic understanding of the bacterial cell division machinery that we have today.","lang":"eng"}],"ddc":["570"],"external_id":{"isi":["001166216800001"],"pmid":["38218128"]},"acknowledgement":"We acknowledge members of the Loose laboratory at ISTA for helpful discussions—in particular M. Kojic for his insightful comments. This work was supported by the Austrian Science Fund (FWF P34607) to M.L.","quality_controlled":"1","file":[{"relation":"main_file","date_created":"2024-07-16T12:07:20Z","file_id":"17265","date_updated":"2024-07-16T12:07:20Z","creator":"dernst","content_type":"application/pdf","checksum":"5d170abbc87585205c010657e4552360","file_size":9995304,"access_level":"open_access","file_name":"2024_EJCB_Radler.pdf","success":1}],"publication_identifier":{"issn":["0171-9335"]},"pmid":1,"day":"01","status":"public","publisher":"Elsevier","publication_status":"published","publication":"European Journal of Cell Biology","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"volume":103,"corr_author":"1","project":[{"_id":"fc38323b-9c52-11eb-aca3-ff8afb4a011d","name":"In vitro reconstitution of bacterial cell division","grant_number":"P34607"}],"doi":"10.1016/j.ejcb.2023.151380","file_date_updated":"2024-07-16T12:07:20Z","month":"03"},{"scopus_import":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"A structurally precise mechanism links an epilepsy-associated KCNC2 potassium channel mutation to interneuron dysfunction","article_type":"original","related_material":{"link":[{"relation":"software","url":"https://github.com/ChrisCurrin/pv-kcnc2 "}]},"intvolume":"       121","author":[{"full_name":"Clatot, Jerome","last_name":"Clatot","first_name":"Jerome"},{"id":"e8321fc5-3091-11eb-8a53-83f309a11ac9","full_name":"Currin, Christopher","last_name":"Currin","orcid":"0000-0002-4809-5059","first_name":"Christopher"},{"last_name":"Liang","first_name":"Qiansheng","full_name":"Liang, Qiansheng"},{"full_name":"Pipatpolkai, Tanadet","first_name":"Tanadet","last_name":"Pipatpolkai"},{"full_name":"Massey, Shavonne L.","first_name":"Shavonne L.","last_name":"Massey"},{"full_name":"Helbig, Ingo","first_name":"Ingo","last_name":"Helbig"},{"full_name":"Delemotte, Lucie","first_name":"Lucie","last_name":"Delemotte"},{"last_name":"Vogels","orcid":"0000-0003-3295-6181","first_name":"Tim P","id":"CB6FF8D2-008F-11EA-8E08-2637E6697425","full_name":"Vogels, Tim P"},{"first_name":"Manuel","last_name":"Covarrubias","full_name":"Covarrubias, Manuel"},{"last_name":"Goldberg","first_name":"Ethan M.","full_name":"Goldberg, Ethan M."}],"year":"2024","article_processing_charge":"Yes (in subscription journal)","has_accepted_license":"1","language":[{"iso":"eng"}],"citation":{"ista":"Clatot J, Currin C, Liang Q, Pipatpolkai T, Massey SL, Helbig I, Delemotte L, Vogels TP, Covarrubias M, Goldberg EM. 2024. A structurally precise mechanism links an epilepsy-associated KCNC2 potassium channel mutation to interneuron dysfunction. Proceedings of the National Academy of Sciences of the United States of America. 121(3), e2307776121.","chicago":"Clatot, Jerome, Christopher Currin, Qiansheng Liang, Tanadet Pipatpolkai, Shavonne L. Massey, Ingo Helbig, Lucie Delemotte, Tim P Vogels, Manuel Covarrubias, and Ethan M. Goldberg. “A Structurally Precise Mechanism Links an Epilepsy-Associated KCNC2 Potassium Channel Mutation to Interneuron Dysfunction.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>. National Academy of Sciences, 2024. <a href=\"https://doi.org/10.1073/pnas.2307776121\">https://doi.org/10.1073/pnas.2307776121</a>.","ieee":"J. Clatot <i>et al.</i>, “A structurally precise mechanism links an epilepsy-associated KCNC2 potassium channel mutation to interneuron dysfunction,” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 121, no. 3. National Academy of Sciences, 2024.","ama":"Clatot J, Currin C, Liang Q, et al. A structurally precise mechanism links an epilepsy-associated KCNC2 potassium channel mutation to interneuron dysfunction. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. 2024;121(3). doi:<a href=\"https://doi.org/10.1073/pnas.2307776121\">10.1073/pnas.2307776121</a>","short":"J. Clatot, C. Currin, Q. Liang, T. Pipatpolkai, S.L. Massey, I. Helbig, L. Delemotte, T.P. Vogels, M. Covarrubias, E.M. Goldberg, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).","mla":"Clatot, Jerome, et al. “A Structurally Precise Mechanism Links an Epilepsy-Associated KCNC2 Potassium Channel Mutation to Interneuron Dysfunction.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 121, no. 3, e2307776121, National Academy of Sciences, 2024, doi:<a href=\"https://doi.org/10.1073/pnas.2307776121\">10.1073/pnas.2307776121</a>.","apa":"Clatot, J., Currin, C., Liang, Q., Pipatpolkai, T., Massey, S. L., Helbig, I., … Goldberg, E. M. (2024). A structurally precise mechanism links an epilepsy-associated KCNC2 potassium channel mutation to interneuron dysfunction. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.2307776121\">https://doi.org/10.1073/pnas.2307776121</a>"},"department":[{"_id":"TiVo"}],"date_published":"2024-01-16T00:00:00Z","_id":"14841","abstract":[{"lang":"eng","text":"De novo heterozygous variants in KCNC2 encoding the voltage-gated potassium (K+) channel subunit Kv3.2 are a recently described cause of developmental and epileptic encephalopathy (DEE). A de novo variant in KCNC2 c.374G > A (p.Cys125Tyr) was identified via exome sequencing in a patient with DEE. Relative to wild-type Kv3.2, Kv3.2-p.Cys125Tyr induces K+ currents exhibiting a large hyperpolarizing shift in the voltage dependence of activation, accelerated activation, and delayed deactivation consistent with a relative stabilization of the open conformation, along with increased current density. Leveraging the cryogenic electron microscopy (cryo-EM) structure of Kv3.1, molecular dynamic simulations suggest that a strong π-π stacking interaction between the variant Tyr125 and Tyr156 in the α-6 helix of the T1 domain promotes a relative stabilization of the open conformation of the channel, which underlies the observed gain of function. A multicompartment computational model of a Kv3-expressing parvalbumin-positive cerebral cortex fast-spiking γ-aminobutyric acidergic (GABAergic) interneuron (PV-IN) demonstrates how the Kv3.2-Cys125Tyr variant impairs neuronal excitability and dysregulates inhibition in cerebral cortex circuits to explain the resulting epilepsy."}],"date_updated":"2025-09-04T11:47:47Z","isi":1,"oa":1,"issue":"3","type":"journal_article","article_number":"e2307776121","date_created":"2024-01-21T23:00:56Z","oa_version":"Published Version","file":[{"date_created":"2025-04-23T13:51:16Z","relation":"main_file","file_id":"19613","content_type":"application/pdf","checksum":"f498c643be81895dd3a69ee90115a782","date_updated":"2025-04-23T13:51:16Z","creator":"dernst","file_name":"2024_PNAS_Clatot.pdf","access_level":"open_access","success":1,"file_size":3060109}],"publication_identifier":{"eissn":["1091-6490"]},"day":"16","pmid":1,"status":"public","publisher":"National Academy of Sciences","publication_status":"published","publication":"Proceedings of the National Academy of Sciences of the United States of America","volume":121,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"},"external_id":{"isi":["001167401000001"],"pmid":["38194456"]},"ddc":["570"],"acknowledgement":"This work was supported by an ERC Consolidator Grant (SYNAPSEEK) to T.P.V., the NOMIS Foundation through the NOMIS Fellowships program at IST Austria to C.B.C., a Jefferson Synaptic Biology Center Pilot Project Grant to M.C., NIH NINDS U54 NS108874 (PI, Alfred L. George), and NIH NINDS R01 NS122887 to E.M.G. The computations were enabled by resources provided by the Swedish National Infrastructure for Computing (SNIC) at the PDC Center for High-Performance Computing, KTH Royal Institute of Technology, partially funded by the Swedish Research Council through grant agreement no. 2018-05973. We thank Akshay Sridhar for the fruitful discussion of the project.","quality_controlled":"1","OA_type":"hybrid","project":[{"_id":"0aacfa84-070f-11eb-9043-d7eb2c709234","call_identifier":"H2020","grant_number":"819603","name":"Learning the shape of synaptic plasticity rules for neuronal architectures and function through machine learning."}],"doi":"10.1073/pnas.2307776121","file_date_updated":"2025-04-23T13:51:16Z","month":"01","ec_funded":1,"OA_place":"publisher"},{"month":"01","doi":"10.1016/j.cub.2023.11.039","corr_author":"1","main_file_link":[{"url":"https://doi.org/10.1016/j.cub.2023.11.039","open_access":"1"}],"publication_status":"published","publisher":"Elsevier","volume":34,"publication":"Current Biology","publication_identifier":{"eissn":["1879-0445"]},"status":"public","day":"08","pmid":1,"external_id":{"pmid":["38194926"]},"quality_controlled":"1","language":[{"iso":"eng"}],"_id":"14842","date_updated":"2025-01-28T06:49:44Z","abstract":[{"lang":"eng","text":"Eva Benkova received a PhD in Biophysics at the Institute of Biophysics of the Czech Academy of Sciences in 1998. After working as a postdoc at the Max Planck Institute in Cologne and the Center for Plant Molecular Biology (ZMBP) in Tübingen, she became a group leader at the Plant Systems Biology Department of the Vlaams Instituut voor Biotechnologie (VIB) in Gent. In 2012, she transitioned to an Assistant Professor position at the Institute of Science and Technology Austria (ISTA) where she was later promoted to Professor. Since 2021, she has served as the Dean of the ISTA Graduate School. As a plant developmental biologist, she focuses on unraveling the molecular mechanisms and principles that underlie hormonal interactions in plants. In her current work, she explores the intricate connections between hormones and regulatory pathways that mediate the perception of environmental stimuli, including abiotic stress and nitrate availability."}],"department":[{"_id":"EvBe"}],"citation":{"mla":"Benková, Eva. “Eva Benkova.” <i>Current Biology</i>, vol. 34, no. 1, Elsevier, 2024, pp. R3–5, doi:<a href=\"https://doi.org/10.1016/j.cub.2023.11.039\">10.1016/j.cub.2023.11.039</a>.","short":"E. Benková, Eva Benkova, Elsevier, 2024.","apa":"Benková, E. (2024). <i>Eva Benkova</i>. <i>Current Biology</i> (Vol. 34, pp. R3–R5). Elsevier. <a href=\"https://doi.org/10.1016/j.cub.2023.11.039\">https://doi.org/10.1016/j.cub.2023.11.039</a>","ama":"Benková E. <i>Eva Benkova</i>. Vol 34. Elsevier; 2024:R3-R5. doi:<a href=\"https://doi.org/10.1016/j.cub.2023.11.039\">10.1016/j.cub.2023.11.039</a>","ieee":"E. Benková, <i>Eva Benkova</i>, vol. 34, no. 1. Elsevier, 2024, pp. R3–R5.","ista":"Benková E. 2024. Eva Benkova, Elsevier,p.","chicago":"Benková, Eva. <i>Eva Benkova</i>. <i>Current Biology</i>. Vol. 34. Elsevier, 2024. <a href=\"https://doi.org/10.1016/j.cub.2023.11.039\">https://doi.org/10.1016/j.cub.2023.11.039</a>."},"page":"R3-R5","date_published":"2024-01-08T00:00:00Z","type":"other_academic_publication","oa_version":"Published Version","date_created":"2024-01-21T23:00:56Z","oa":1,"issue":"1","title":"Eva Benkova","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"No","year":"2024","author":[{"full_name":"Benková, Eva","id":"38F4F166-F248-11E8-B48F-1D18A9856A87","last_name":"Benková","orcid":"0000-0002-8510-9739","first_name":"Eva"}],"intvolume":"        34"},{"publication_identifier":{"issn":["0006-3495"],"eissn":["1542-0086"]},"file":[{"date_created":"2024-07-16T12:09:55Z","relation":"main_file","file_id":"17266","checksum":"1c8fe1cf950394875b65b90da86428ff","content_type":"application/pdf","creator":"dernst","date_updated":"2024-07-16T12:09:55Z","success":1,"access_level":"open_access","file_name":"2024_BiophysicalJournal_Azadbakht.pdf","file_size":3189926}],"status":"public","pmid":1,"day":"06","publication_status":"published","publisher":"Elsevier","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"},"volume":123,"publication":"Biophysical Journal","acknowledgement":"We gratefully acknowledge useful discussions with Casper van der Wel, help by Yogesh Shelke with PAA coverslip preparation, and support by Rachel Doherty with particle functionalization. A.A. and D.J.K. would like to thank Timon Idema and George Dadunashvili for initial attempts to simulate the experimental system. D.J.K. would like to thank the physics department at Leiden University for funding the PhD position of A.A. B.M. and A.Š. acknowledge funding by the European Union’s Horizon 2020 research and innovation programme (ERC starting grant no. 802960).","ddc":["570"],"external_id":{"pmid":["38158654"],"isi":["001185235900001"]},"quality_controlled":"1","project":[{"call_identifier":"H2020","name":"Non-Equilibrium Protein Assembly: from Building Blocks to Biological Machines","grant_number":"802960","_id":"eba2549b-77a9-11ec-83b8-a81e493eae4e"}],"file_date_updated":"2024-07-16T12:09:55Z","doi":"10.1016/j.bpj.2023.12.020","month":"02","ec_funded":1,"scopus_import":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"Nonadditivity in interactions between three membrane-wrapped colloidal spheres","article_type":"original","author":[{"first_name":"Ali","last_name":"Azadbakht","full_name":"Azadbakht, Ali"},{"full_name":"Meadowcroft, Billie","id":"a4725fd6-932b-11ed-81e2-c098c7f37ae1","last_name":"Meadowcroft","orcid":"0000-0003-3441-1337","first_name":"Billie"},{"last_name":"Majek","first_name":"Juraj","id":"3e6d9473-f38e-11ec-8ae0-c4e05a8aa9e1","full_name":"Majek, Juraj"},{"full_name":"Šarić, Anđela","id":"bf63d406-f056-11eb-b41d-f263a6566d8b","orcid":"0000-0002-7854-2139","last_name":"Šarić","first_name":"Anđela"},{"full_name":"Kraft, Daniela J.","last_name":"Kraft","first_name":"Daniela J."}],"intvolume":"       123","article_processing_charge":"Yes (in subscription journal)","year":"2024","language":[{"iso":"eng"}],"has_accepted_license":"1","_id":"14844","abstract":[{"text":"Many cell functions require a concerted effort from multiple membrane proteins, for example, for signaling, cell division, and endocytosis. One contribution to their successful self-organization stems from the membrane deformations that these proteins induce. While the pairwise interaction potential of two membrane-deforming spheres has recently been measured, membrane-deformation-induced interactions have been predicted to be nonadditive, and hence their collective behavior cannot be deduced from this measurement. We here employ a colloidal model system consisting of adhesive spheres and giant unilamellar vesicles to test these predictions by measuring the interaction potential of the simplest case of three membrane-deforming, spherical particles. We quantify their interactions and arrangements and, for the first time, experimentally confirm and quantify the nonadditive nature of membrane-deformation-induced interactions. We furthermore conclude that there exist two favorable configurations on the membrane: (1) a linear and (2) a triangular arrangement of the three spheres. Using Monte Carlo simulations, we corroborate the experimentally observed energy minima and identify a lowering of the membrane deformation as the cause for the observed configurations. The high symmetry of the preferred arrangements for three particles suggests that arrangements of many membrane-deforming objects might follow simple rules.","lang":"eng"}],"date_updated":"2025-09-04T11:46:15Z","page":"307-316","date_published":"2024-02-06T00:00:00Z","department":[{"_id":"AnSa"}],"citation":{"mla":"Azadbakht, Ali, et al. “Nonadditivity in Interactions between Three Membrane-Wrapped Colloidal Spheres.” <i>Biophysical Journal</i>, vol. 123, no. 3, Elsevier, 2024, pp. 307–16, doi:<a href=\"https://doi.org/10.1016/j.bpj.2023.12.020\">10.1016/j.bpj.2023.12.020</a>.","short":"A. Azadbakht, B. Meadowcroft, J. Majek, A. Šarić, D.J. Kraft, Biophysical Journal 123 (2024) 307–316.","apa":"Azadbakht, A., Meadowcroft, B., Majek, J., Šarić, A., &#38; Kraft, D. J. (2024). Nonadditivity in interactions between three membrane-wrapped colloidal spheres. <i>Biophysical Journal</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.bpj.2023.12.020\">https://doi.org/10.1016/j.bpj.2023.12.020</a>","ista":"Azadbakht A, Meadowcroft B, Majek J, Šarić A, Kraft DJ. 2024. Nonadditivity in interactions between three membrane-wrapped colloidal spheres. Biophysical Journal. 123(3), 307–316.","chicago":"Azadbakht, Ali, Billie Meadowcroft, Juraj Majek, Anđela Šarić, and Daniela J. Kraft. “Nonadditivity in Interactions between Three Membrane-Wrapped Colloidal Spheres.” <i>Biophysical Journal</i>. Elsevier, 2024. <a href=\"https://doi.org/10.1016/j.bpj.2023.12.020\">https://doi.org/10.1016/j.bpj.2023.12.020</a>.","ama":"Azadbakht A, Meadowcroft B, Majek J, Šarić A, Kraft DJ. Nonadditivity in interactions between three membrane-wrapped colloidal spheres. <i>Biophysical Journal</i>. 2024;123(3):307-316. doi:<a href=\"https://doi.org/10.1016/j.bpj.2023.12.020\">10.1016/j.bpj.2023.12.020</a>","ieee":"A. Azadbakht, B. Meadowcroft, J. Majek, A. Šarić, and D. J. Kraft, “Nonadditivity in interactions between three membrane-wrapped colloidal spheres,” <i>Biophysical Journal</i>, vol. 123, no. 3. Elsevier, pp. 307–316, 2024."},"isi":1,"oa":1,"issue":"3","type":"journal_article","date_created":"2024-01-21T23:00:56Z","oa_version":"Published Version"},{"_id":"14845","date_updated":"2025-09-04T11:49:14Z","abstract":[{"text":"We study a linear rotor in a bosonic bath within the angulon formalism. Our focus is on systems where isotropic or anisotropic impurity-boson interactions support a shallow bound state. To study the fate of the angulon in the vicinity of bound-state formation, we formulate a beyond-linear-coupling angulon Hamiltonian. First, we use it to study attractive, spherically symmetric impurity-boson interactions for which the linear rotor can be mapped onto a static impurity. The well-known polaron formalism provides an adequate description in this limit. Second, we consider anisotropic potentials, and show that the presence of a shallow bound state with pronounced anisotropic character leads to a many-body instability that washes out the angulon dynamics.","lang":"eng"}],"citation":{"chicago":"Dome, Tibor, Artem Volosniev, Areg Ghazaryan, Laleh Safari, Richard Schmidt, and Mikhail Lemeshko. “Linear Rotor in an Ideal Bose Gas near the Threshold for Binding.” <i>Physical Review B</i>. American Physical Society, 2024. <a href=\"https://doi.org/10.1103/PhysRevB.109.014102\">https://doi.org/10.1103/PhysRevB.109.014102</a>.","ista":"Dome T, Volosniev A, Ghazaryan A, Safari L, Schmidt R, Lemeshko M. 2024. Linear rotor in an ideal Bose gas near the threshold for binding. Physical Review B. 109(1), 014102.","ieee":"T. Dome, A. Volosniev, A. Ghazaryan, L. Safari, R. Schmidt, and M. Lemeshko, “Linear rotor in an ideal Bose gas near the threshold for binding,” <i>Physical Review B</i>, vol. 109, no. 1. American Physical Society, 2024.","ama":"Dome T, Volosniev A, Ghazaryan A, Safari L, Schmidt R, Lemeshko M. Linear rotor in an ideal Bose gas near the threshold for binding. <i>Physical Review B</i>. 2024;109(1). doi:<a href=\"https://doi.org/10.1103/PhysRevB.109.014102\">10.1103/PhysRevB.109.014102</a>","apa":"Dome, T., Volosniev, A., Ghazaryan, A., Safari, L., Schmidt, R., &#38; Lemeshko, M. (2024). Linear rotor in an ideal Bose gas near the threshold for binding. <i>Physical Review B</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevB.109.014102\">https://doi.org/10.1103/PhysRevB.109.014102</a>","mla":"Dome, Tibor, et al. “Linear Rotor in an Ideal Bose Gas near the Threshold for Binding.” <i>Physical Review B</i>, vol. 109, no. 1, 014102, American Physical Society, 2024, doi:<a href=\"https://doi.org/10.1103/PhysRevB.109.014102\">10.1103/PhysRevB.109.014102</a>.","short":"T. Dome, A. Volosniev, A. Ghazaryan, L. Safari, R. Schmidt, M. Lemeshko, Physical Review B 109 (2024)."},"department":[{"_id":"MiLe"}],"date_published":"2024-01-01T00:00:00Z","language":[{"iso":"eng"}],"issue":"1","isi":1,"oa":1,"oa_version":"Preprint","date_created":"2024-01-21T23:00:57Z","article_number":"014102","type":"journal_article","title":"Linear rotor in an ideal Bose gas near the threshold for binding","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","scopus_import":"1","intvolume":"       109","author":[{"id":"7e3293e2-b9dc-11ee-97a9-cd73400f6994","full_name":"Dome, Tibor","first_name":"Tibor","orcid":"0000-0003-2586-3702","last_name":"Dome"},{"orcid":"0000-0003-0393-5525","last_name":"Volosniev","first_name":"Artem","full_name":"Volosniev, Artem","id":"37D278BC-F248-11E8-B48F-1D18A9856A87"},{"id":"4AF46FD6-F248-11E8-B48F-1D18A9856A87","full_name":"Ghazaryan, Areg","last_name":"Ghazaryan","orcid":"0000-0001-9666-3543","first_name":"Areg"},{"first_name":"Laleh","last_name":"Safari","id":"3C325E5E-F248-11E8-B48F-1D18A9856A87","full_name":"Safari, Laleh"},{"full_name":"Schmidt, Richard","first_name":"Richard","last_name":"Schmidt"},{"orcid":"0000-0002-6990-7802","last_name":"Lemeshko","first_name":"Mikhail","full_name":"Lemeshko, Mikhail","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87"}],"article_type":"original","article_processing_charge":"No","year":"2024","doi":"10.1103/PhysRevB.109.014102","OA_type":"green","project":[{"call_identifier":"H2020","grant_number":"801770","name":"Angulon: physics and applications of a new quasiparticle","_id":"2688CF98-B435-11E9-9278-68D0E5697425"},{"_id":"260C2330-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"754411","name":"ISTplus - Postdoctoral Fellowships"}],"month":"01","ec_funded":1,"main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2308.03852","open_access":"1"}],"OA_place":"repository","corr_author":"1","status":"public","day":"01","publication_identifier":{"eissn":["2469-9969"],"issn":["2469-9950"]},"arxiv":1,"volume":109,"publication":"Physical Review B","publication_status":"published","publisher":"American Physical Society","quality_controlled":"1","acknowledgement":"We would like to thank G. Bighin, I. Cherepanov, E. Paerschke, and E. Yakaboylu for insightful discussions on a wide range of topics. This work has been supported by the European Research Council (ERC) Starting Grant No. 801770 (ANGULON). A.G. and A.G.V. acknowledge support from the European Union’s Horizon 2020 research and innovation\r\nprogram under the Marie Skłodowska-Curie Grant Agreement No. 754411. Numerical calculations were performed on the Euler cluster managed by the HPC team at ETH Zurich.\r\nR.S. acknowledges support by the Deutsche Forschungsgemeinschaft under Germany’s Excellence Strategy Grant No. EXC 2181/1-390900948 (the Heidelberg STRUCTURES Excellence Cluster). T.D. acknowledges support from the Isaac Newton Studentship and the Science and Technology Facilities Council under Grant No. ST/V50659X/1.","external_id":{"arxiv":["2308.03852"],"isi":["001172754500002"]}},{"quality_controlled":"1","acknowledgement":"We would like to thank A. McDougall, E. Hannezo and the Heisenberg lab for fruitful discussions and reagents. We also thank E. Munro for the iMyo-YFP and Bra>iMyo-mScarlet constructs. This research was supported by the Scientific Service Units of the Institute of Science and Technology Austria through resources provided by the Electron Microscopy Facility, Imaging and Optics Facility and the Nanofabrication Facility. This work was supported by a Joint Project Grant from the FWF (I 3601-B27).","ddc":["530"],"external_id":{"isi":["001138880800005"],"pmid":["38370025"]},"status":"public","day":"01","pmid":1,"publication_identifier":{"eissn":["1745-2481"],"issn":["1745-2473"]},"file":[{"relation":"main_file","date_created":"2024-07-16T12:12:43Z","file_id":"17267","creator":"dernst","date_updated":"2024-07-16T12:12:43Z","content_type":"application/pdf","checksum":"7891ebe7c900ae47469ab127031dd1ec","file_size":9897883,"access_level":"open_access","file_name":"2024_NaturePhysics_CaballeroMancebo.pdf","success":1}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"volume":20,"publication":"Nature Physics","publication_status":"published","publisher":"Springer Nature","corr_author":"1","file_date_updated":"2024-07-16T12:12:43Z","doi":"10.1038/s41567-023-02302-1","project":[{"grant_number":"I03601","name":"Control of embryonic cleavage pattern","call_identifier":"FWF","_id":"2646861A-B435-11E9-9278-68D0E5697425"}],"month":"02","intvolume":"        20","author":[{"last_name":"Caballero Mancebo","orcid":"0000-0002-5223-3346","first_name":"Silvia","id":"2F1E1758-F248-11E8-B48F-1D18A9856A87","full_name":"Caballero Mancebo, Silvia"},{"full_name":"Shinde, Rushikesh","first_name":"Rushikesh","last_name":"Shinde"},{"orcid":"0000-0002-8176-4824","last_name":"Bolger-Munro","first_name":"Madison","full_name":"Bolger-Munro, Madison","id":"516F03FA-93A3-11EA-A7C5-D6BE3DDC885E"},{"first_name":"Matilda","orcid":"0000-0002-3415-4628","last_name":"Peruzzo","id":"3F920B30-F248-11E8-B48F-1D18A9856A87","full_name":"Peruzzo, Matilda"},{"last_name":"Szep","first_name":"Gregory","full_name":"Szep, Gregory","id":"4BFB7762-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Irene","last_name":"Steccari","full_name":"Steccari, Irene","id":"2705C766-9FE2-11EA-B224-C6773DDC885E"},{"first_name":"David","last_name":"Labrousse Arias","full_name":"Labrousse Arias, David","id":"CD573DF4-9ED3-11E9-9D77-3223E6697425"},{"orcid":"0000-0002-9438-4783","last_name":"Zheden","first_name":"Vanessa","id":"39C5A68A-F248-11E8-B48F-1D18A9856A87","full_name":"Zheden, Vanessa"},{"first_name":"Jack","last_name":"Merrin","orcid":"0000-0001-5145-4609","full_name":"Merrin, Jack","id":"4515C308-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Callan-Jones, Andrew","first_name":"Andrew","last_name":"Callan-Jones"},{"full_name":"Voituriez, Raphaël","first_name":"Raphaël","last_name":"Voituriez"},{"id":"39427864-F248-11E8-B48F-1D18A9856A87","full_name":"Heisenberg, Carl-Philipp J","first_name":"Carl-Philipp J","orcid":"0000-0002-0912-4566","last_name":"Heisenberg"}],"related_material":{"link":[{"description":"News on ISTA Website","relation":"press_release","url":"https://ista.ac.at/en/news/stranger-than-friction-a-force-initiating-life/"}]},"article_type":"original","article_processing_charge":"Yes (in subscription journal)","year":"2024","title":"Friction forces determine cytoplasmic reorganization and shape changes of ascidian oocytes upon fertilization","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","scopus_import":"1","isi":1,"oa":1,"date_created":"2024-01-21T23:00:57Z","oa_version":"Published Version","type":"journal_article","_id":"14846","abstract":[{"text":"Contraction and flow of the actin cell cortex have emerged as a common principle by which cells reorganize their cytoplasm and take shape. However, how these cortical flows interact with adjacent cytoplasmic components, changing their form and localization, and how this affects cytoplasmic organization and cell shape remains unclear. Here we show that in ascidian oocytes, the cooperative activities of cortical actomyosin flows and deformation of the adjacent mitochondria-rich myoplasm drive oocyte cytoplasmic reorganization and shape changes following fertilization. We show that vegetal-directed cortical actomyosin flows, established upon oocyte fertilization, lead to both the accumulation of cortical actin at the vegetal pole of the zygote and compression and local buckling of the adjacent elastic solid-like myoplasm layer due to friction forces generated at their interface. Once cortical flows have ceased, the multiple myoplasm buckles resolve into one larger buckle, which again drives the formation of the contraction pole—a protuberance of the zygote’s vegetal pole where maternal mRNAs accumulate. Thus, our findings reveal a mechanism where cortical actomyosin network flows determine cytoplasmic reorganization and cell shape by deforming adjacent cytoplasmic components through friction forces.","lang":"eng"}],"date_updated":"2025-09-04T11:48:28Z","department":[{"_id":"CaHe"},{"_id":"JoFi"},{"_id":"MiSi"},{"_id":"EM-Fac"},{"_id":"NanoFab"}],"citation":{"apa":"Caballero Mancebo, S., Shinde, R., Bolger-Munro, M., Peruzzo, M., Szep, G., Steccari, I., … Heisenberg, C.-P. J. (2024). Friction forces determine cytoplasmic reorganization and shape changes of ascidian oocytes upon fertilization. <i>Nature Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41567-023-02302-1\">https://doi.org/10.1038/s41567-023-02302-1</a>","mla":"Caballero Mancebo, Silvia, et al. “Friction Forces Determine Cytoplasmic Reorganization and Shape Changes of Ascidian Oocytes upon Fertilization.” <i>Nature Physics</i>, vol. 20, Springer Nature, 2024, pp. 310–21, doi:<a href=\"https://doi.org/10.1038/s41567-023-02302-1\">10.1038/s41567-023-02302-1</a>.","short":"S. Caballero Mancebo, R. Shinde, M. Bolger-Munro, M. Peruzzo, G. Szep, I. Steccari, D. Labrousse Arias, V. Zheden, J. Merrin, A. Callan-Jones, R. Voituriez, C.-P.J. Heisenberg, Nature Physics 20 (2024) 310–321.","ieee":"S. Caballero Mancebo <i>et al.</i>, “Friction forces determine cytoplasmic reorganization and shape changes of ascidian oocytes upon fertilization,” <i>Nature Physics</i>, vol. 20. Springer Nature, pp. 310–321, 2024.","ama":"Caballero Mancebo S, Shinde R, Bolger-Munro M, et al. Friction forces determine cytoplasmic reorganization and shape changes of ascidian oocytes upon fertilization. <i>Nature Physics</i>. 2024;20:310-321. doi:<a href=\"https://doi.org/10.1038/s41567-023-02302-1\">10.1038/s41567-023-02302-1</a>","chicago":"Caballero Mancebo, Silvia, Rushikesh Shinde, Madison Bolger-Munro, Matilda Peruzzo, Gregory Szep, Irene Steccari, David Labrousse Arias, et al. “Friction Forces Determine Cytoplasmic Reorganization and Shape Changes of Ascidian Oocytes upon Fertilization.” <i>Nature Physics</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1038/s41567-023-02302-1\">https://doi.org/10.1038/s41567-023-02302-1</a>.","ista":"Caballero Mancebo S, Shinde R, Bolger-Munro M, Peruzzo M, Szep G, Steccari I, Labrousse Arias D, Zheden V, Merrin J, Callan-Jones A, Voituriez R, Heisenberg C-PJ. 2024. Friction forces determine cytoplasmic reorganization and shape changes of ascidian oocytes upon fertilization. Nature Physics. 20, 310–321."},"date_published":"2024-02-01T00:00:00Z","page":"310-321","acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"Bio"},{"_id":"NanoFab"}],"language":[{"iso":"eng"}],"has_accepted_license":"1"},{"language":[{"iso":"eng"}],"has_accepted_license":"1","_id":"14850","date_updated":"2025-09-04T11:50:21Z","abstract":[{"text":"Elaborate sexual signals are thought to have evolved and be maintained to serve as honest indicators of signaller quality. One measure of quality is health, which can be affected by parasite infection. Cnemaspis mysoriensis is a diurnal gecko that is often infested with ectoparasites in the wild, and males of this species express visual (coloured gular patches) and chemical (femoral gland secretions) traits that receivers could assess during social interactions. In this paper, we tested whether ectoparasites affect individual health, and whether signal quality is an indicator of ectoparasite levels. In wild lizards, we found that ectoparasite level was negatively correlated with body condition in both sexes. Moreover, some characteristics of both visual and chemical traits in males were strongly associated with ectoparasite levels. Specifically, males with higher ectoparasite levels had yellow gular patches with lower brightness and chroma, and chemical secretions with a lower proportion of aromatic compounds. We then determined whether ectoparasite levels in males influence female behaviour. Using sequential choice trials, wherein females were provided with either the visual or the chemical signals of wild-caught males that varied in ectoparasite level, we found that only chemical secretions evoked an elevated female response towards less parasitised males. Simultaneous choice trials in which females were exposed to the chemical secretions from males that varied in parasite level further confirmed a preference for males with lower parasites loads. Overall, we find that although health (body condition) or ectoparasite load can be honestly advertised through multiple modalities, the parasite-mediated female response is exclusively driven by chemical signals.</jats:p>","lang":"eng"}],"date_published":"2024-01-10T00:00:00Z","citation":{"ista":"Pal A, Joshi M, Thaker M. 2024. Too much information? Males convey parasite levels using more signal modalities than females utilise. Journal of Experimental Biology. 227(1), jeb246217.","chicago":"Pal, Arka, Mihir Joshi, and Maria Thaker. “Too Much Information? Males Convey Parasite Levels Using More Signal Modalities than Females Utilise.” <i>Journal of Experimental Biology</i>. The Company of Biologists, 2024. <a href=\"https://doi.org/10.1242/jeb.246217\">https://doi.org/10.1242/jeb.246217</a>.","ama":"Pal A, Joshi M, Thaker M. Too much information? Males convey parasite levels using more signal modalities than females utilise. <i>Journal of Experimental Biology</i>. 2024;227(1). doi:<a href=\"https://doi.org/10.1242/jeb.246217\">10.1242/jeb.246217</a>","ieee":"A. Pal, M. Joshi, and M. Thaker, “Too much information? Males convey parasite levels using more signal modalities than females utilise,” <i>Journal of Experimental Biology</i>, vol. 227, no. 1. The Company of Biologists, 2024.","short":"A. Pal, M. Joshi, M. Thaker, Journal of Experimental Biology 227 (2024).","mla":"Pal, Arka, et al. “Too Much Information? Males Convey Parasite Levels Using More Signal Modalities than Females Utilise.” <i>Journal of Experimental Biology</i>, vol. 227, no. 1, jeb246217, The Company of Biologists, 2024, doi:<a href=\"https://doi.org/10.1242/jeb.246217\">10.1242/jeb.246217</a>.","apa":"Pal, A., Joshi, M., &#38; Thaker, M. (2024). Too much information? Males convey parasite levels using more signal modalities than females utilise. <i>Journal of Experimental Biology</i>. The Company of Biologists. <a href=\"https://doi.org/10.1242/jeb.246217\">https://doi.org/10.1242/jeb.246217</a>"},"department":[{"_id":"NiBa"}],"article_number":"jeb246217","type":"journal_article","date_created":"2024-01-22T08:14:49Z","oa_version":"Published Version","oa":1,"isi":1,"issue":"1","scopus_import":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"Too much information? Males convey parasite levels using more signal modalities than females utilise","article_processing_charge":"Yes (via OA deal)","keyword":["Insect Science","Molecular Biology","Animal Science and Zoology","Aquatic Science","Physiology","Ecology","Evolution","Behavior and Systematics"],"year":"2024","article_type":"original","related_material":{"link":[{"url":"https://github.com/arka-pal/Cnemaspis-SexualSignaling","relation":"software"}]},"author":[{"last_name":"Pal","orcid":"0000-0002-4530-8469","first_name":"Arka","id":"6AAB2240-CA9A-11E9-9C1A-D9D1E5697425","full_name":"Pal, Arka"},{"full_name":"Joshi, Mihir","first_name":"Mihir","last_name":"Joshi"},{"full_name":"Thaker, Maria","last_name":"Thaker","first_name":"Maria"}],"intvolume":"       227","month":"01","file_date_updated":"2024-01-23T12:08:24Z","doi":"10.1242/jeb.246217","corr_author":"1","publication_status":"published","publisher":"The Company of Biologists","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"volume":227,"publication":"Journal of Experimental Biology","publication_identifier":{"eissn":["0022-0949"],"issn":["1477-9145"]},"file":[{"relation":"main_file","date_created":"2024-01-23T12:08:24Z","file_id":"14877","date_updated":"2024-01-23T12:08:24Z","creator":"dernst","content_type":"application/pdf","checksum":"136325372f6f45abaa62a71e2d23bfb6","file_size":594128,"file_name":"2024_JourExperimBiology_Pal.pdf","access_level":"open_access","success":1}],"status":"public","pmid":1,"day":"10","acknowledgement":"We thank Anuradha Batabyal and Shakilur Kabir for scientific discussions, and help with sampling and colour analyses. We thank Muralidhar and the central LCMS facility of the IISc for their technical support with the GCMS.\r\nResearch funding was provided by the Department of Science and Technology Fund for Improvement of S&T Infrastructure (DST-FIST), the Department of Biotechnology-Indian Institute of Science (DBT-IISc) partnership program and a Science and Engineering Research Board (SERB) grant to M.T. (EMR/2017/002228). Open Access funding provided by Indian Institute of Science. Deposited in PMC for immediate release.","external_id":{"pmid":["38054353"],"isi":["001214515700016"]},"ddc":["570"],"quality_controlled":"1"},{"corr_author":"1","month":"02","file_date_updated":"2024-01-23T12:30:45Z","doi":"10.1093/mnras/stad3853","acknowledgement":"We thank the anonymous referee for the constructive feedback that helped to improve the manuscript. We thank Michael Maseda, Daniel Schaerer, Charlotte Simmonds, and Rashmi Gottumukkala for useful comments and productive discussions. We also thank the organizers and participants of the 24th MUSE Science Busy Week in Leiden. IGK acknowledges an Excellence Master Fellowship granted by the Faculty of Science of the University of Geneva. This work has received funding from the Swiss State Secretariat for Education, Research and Innovation (SERI) under contract number MB22.00072, as well as from the Swiss National Science Foundation (SNSF) through project grant number 200020_207349 and SNSF Professorship grant number 190079. The Cosmic Dawn Center (DAWN) is funded by the Danish National Research Foundation under grant number 140. This paper is based on observations collected at the European Organisation for Astronomical Research in the Southern Hemisphere under ESO programmes 094.A-0289(B), 095.A-0010(A), 096.A-0045(A), 096.A-0045(B), 094.A-0205, 095.A-0240, 096.A-0090, 097.A-0160, and 098.A-0017. We made extensive use of several open-source software packages and we are thankful to the respective authors for sharing their work: NUMPY (Harris et al. 2020), ASTROPY (Astropy Collaboration 2022), MATPLOTLIB (Hunter 2007), IPYTHON (Perez & Granger 2007), and TOPCAT (Taylor 2005).","ddc":["520"],"external_id":{"isi":["001133672400004"],"arxiv":["2305.07044"]},"quality_controlled":"1","publication_status":"published","publisher":"Oxford University Press","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"volume":527,"publication":"Monthly Notices of the Royal Astronomical Society","publication_identifier":{"eissn":["1365-2966"],"issn":["0035-8711"]},"file":[{"creator":"dernst","date_updated":"2024-01-23T12:30:45Z","content_type":"application/pdf","checksum":"9d02df4035c4951cf63dee0db1e462e9","file_size":4521738,"file_name":"2024_MNAstronomSoc_Kramarenko.pdf","access_level":"open_access","success":1,"relation":"main_file","date_created":"2024-01-23T12:30:45Z","file_id":"14879"}],"arxiv":1,"status":"public","day":"01","type":"journal_article","date_created":"2024-01-22T08:22:17Z","oa_version":"Published Version","oa":1,"isi":1,"issue":"4","language":[{"iso":"eng"}],"has_accepted_license":"1","DOAJ_listed":"1","_id":"14852","abstract":[{"text":"The physical conditions giving rise to high escape fractions of ionizing radiation (LyC fesc) in star-forming galaxies – most likely protagonists of cosmic reionization – are not yet fully understood. Using the VLT/MUSE observations of ∼1400 Ly α emitters at 2.9 &amp;lt; z &amp;lt; 6.7, we compare stacked rest-frame UV spectra of candidates for LyC leakers and non-leakers selected based on their Ly α profiles. We find that the stacks of potential LyC leakers, i.e. galaxies with narrow, symmetric Ly α profiles with small peak separation, generally show (i) strong nebular O iii]λ1666, [Si iii]λ1883, and [C iii]λ1907 +C iii]λ1909 emission, indicating a high-ionization state of the interstellar medium (ISM); (ii) high equivalent widths of He iiλ1640 (∼1 − 3 Å), suggesting the presence of hard ionizing radiation fields; (iii) Si ii*λ1533 emission, revealing substantial amounts of neutral hydrogen off the line of sight; (iv) high C ivλλ1548,1550 to [C iii]λ1907 +C iii]λ1909 ratios (C iv/C iii] ≳0.75) , signalling the presence of low column density channels in the ISM. In contrast, the stacks with broad, asymmetric Ly α profiles with large peak separation show weak nebular emission lines, low He iiλ1640 equivalent widths (≲1 Å), and low C iv/C iii] (≲0.25), implying low-ionization states and high-neutral hydrogen column densities. Our results suggest that C iv/C iii] might be sensitive to the physical conditions that govern LyC photon escape, providing a promising tool for identification of ionizing sources among star-forming galaxies in the epoch of reionization.","lang":"eng"}],"date_updated":"2025-09-04T11:51:50Z","page":"9853-9871","department":[{"_id":"GradSch"},{"_id":"JoMa"}],"citation":{"apa":"Kramarenko, I., Kerutt, J., Verhamme, A., Oesch, P. A., Barrufet, L., Matthee, J. J., … Thai, T. T. (2024). Linking UV spectral properties of MUSE Ly α emitters at <i>z</i> ≳ 3 to Lyman continuum escape. <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/mnras/stad3853\">https://doi.org/10.1093/mnras/stad3853</a>","short":"I. Kramarenko, J. Kerutt, A. Verhamme, P.A. Oesch, L. Barrufet, J.J. Matthee, H. Kusakabe, I. Goovaerts, T.T. Thai, Monthly Notices of the Royal Astronomical Society 527 (2024) 9853–9871.","mla":"Kramarenko, Ivan, et al. “Linking UV Spectral Properties of MUSE Ly α Emitters at <i>z</i> ≳ 3 to Lyman Continuum Escape.” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 527, no. 4, Oxford University Press, 2024, pp. 9853–71, doi:<a href=\"https://doi.org/10.1093/mnras/stad3853\">10.1093/mnras/stad3853</a>.","ieee":"I. Kramarenko <i>et al.</i>, “Linking UV spectral properties of MUSE Ly α emitters at <i>z</i> ≳ 3 to Lyman continuum escape,” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 527, no. 4. Oxford University Press, pp. 9853–9871, 2024.","ama":"Kramarenko I, Kerutt J, Verhamme A, et al. Linking UV spectral properties of MUSE Ly α emitters at <i>z</i> ≳ 3 to Lyman continuum escape. <i>Monthly Notices of the Royal Astronomical Society</i>. 2024;527(4):9853-9871. doi:<a href=\"https://doi.org/10.1093/mnras/stad3853\">10.1093/mnras/stad3853</a>","chicago":"Kramarenko, Ivan, J Kerutt, A Verhamme, P A Oesch, L Barrufet, Jorryt J Matthee, H Kusakabe, I Goovaerts, and T T Thai. “Linking UV Spectral Properties of MUSE Ly α Emitters at <i>z</i> ≳ 3 to Lyman Continuum Escape.” <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press, 2024. <a href=\"https://doi.org/10.1093/mnras/stad3853\">https://doi.org/10.1093/mnras/stad3853</a>.","ista":"Kramarenko I, Kerutt J, Verhamme A, Oesch PA, Barrufet L, Matthee JJ, Kusakabe H, Goovaerts I, Thai TT. 2024. Linking UV spectral properties of MUSE Ly α emitters at <i>z</i> ≳ 3 to Lyman continuum escape. Monthly Notices of the Royal Astronomical Society. 527(4), 9853–9871."},"date_published":"2024-02-01T00:00:00Z","article_processing_charge":"Yes","keyword":["Space and Planetary Science","Astronomy and Astrophysics"],"year":"2024","article_type":"original","intvolume":"       527","author":[{"id":"9a9394cb-3200-11ee-973b-f5ba2a8b16e4","full_name":"Kramarenko, Ivan","last_name":"Kramarenko","orcid":"0000-0001-5346-6048","first_name":"Ivan"},{"full_name":"Kerutt, J","first_name":"J","last_name":"Kerutt"},{"full_name":"Verhamme, A","first_name":"A","last_name":"Verhamme"},{"full_name":"Oesch, P A","first_name":"P A","last_name":"Oesch"},{"first_name":"L","last_name":"Barrufet","full_name":"Barrufet, L"},{"last_name":"Matthee","orcid":"0000-0003-2871-127X","first_name":"Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720","full_name":"Matthee, Jorryt J"},{"full_name":"Kusakabe, H","first_name":"H","last_name":"Kusakabe"},{"full_name":"Goovaerts, I","first_name":"I","last_name":"Goovaerts"},{"first_name":"T T","last_name":"Thai","full_name":"Thai, T T"}],"scopus_import":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"Linking UV spectral properties of MUSE Ly α emitters at <i>z</i> ≳ 3 to Lyman continuum escape"},{"author":[{"full_name":"Davoli, Elisa","last_name":"Davoli","first_name":"Elisa"},{"full_name":"D’Elia, Lorenza","first_name":"Lorenza","last_name":"D’Elia"},{"id":"71523d30-15b2-11ec-abd3-f80aa909d6b0","full_name":"Ingmanns, Jonas","last_name":"Ingmanns","first_name":"Jonas"}],"intvolume":"        34","article_type":"original","year":"2024","article_processing_charge":"No","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"Stochastic homogenization of micromagnetic energies and emergence of magnetic skyrmions","scopus_import":"1","issue":"2","isi":1,"oa":1,"oa_version":"Preprint","date_created":"2024-01-28T23:01:42Z","type":"journal_article","article_number":"30","date_published":"2024-01-23T00:00:00Z","citation":{"ieee":"E. Davoli, L. D’Elia, and J. Ingmanns, “Stochastic homogenization of micromagnetic energies and emergence of magnetic skyrmions,” <i>Journal of Nonlinear Science</i>, vol. 34, no. 2. Springer Nature, 2024.","ama":"Davoli E, D’Elia L, Ingmanns J. Stochastic homogenization of micromagnetic energies and emergence of magnetic skyrmions. <i>Journal of Nonlinear Science</i>. 2024;34(2). doi:<a href=\"https://doi.org/10.1007/s00332-023-10005-3\">10.1007/s00332-023-10005-3</a>","ista":"Davoli E, D’Elia L, Ingmanns J. 2024. Stochastic homogenization of micromagnetic energies and emergence of magnetic skyrmions. Journal of Nonlinear Science. 34(2), 30.","chicago":"Davoli, Elisa, Lorenza D’Elia, and Jonas Ingmanns. “Stochastic Homogenization of Micromagnetic Energies and Emergence of Magnetic Skyrmions.” <i>Journal of Nonlinear Science</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1007/s00332-023-10005-3\">https://doi.org/10.1007/s00332-023-10005-3</a>.","short":"E. Davoli, L. D’Elia, J. Ingmanns, Journal of Nonlinear Science 34 (2024).","mla":"Davoli, Elisa, et al. “Stochastic Homogenization of Micromagnetic Energies and Emergence of Magnetic Skyrmions.” <i>Journal of Nonlinear Science</i>, vol. 34, no. 2, 30, Springer Nature, 2024, doi:<a href=\"https://doi.org/10.1007/s00332-023-10005-3\">10.1007/s00332-023-10005-3</a>.","apa":"Davoli, E., D’Elia, L., &#38; Ingmanns, J. (2024). Stochastic homogenization of micromagnetic energies and emergence of magnetic skyrmions. <i>Journal of Nonlinear Science</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00332-023-10005-3\">https://doi.org/10.1007/s00332-023-10005-3</a>"},"department":[{"_id":"JuFi"}],"abstract":[{"lang":"eng","text":"We perform a stochastic homogenization analysis for composite materials exhibiting a random microstructure. Under the assumptions of stationarity and ergodicity, we characterize the Gamma-limit of a micromagnetic energy functional defined on magnetizations taking value in the unit sphere and including both symmetric and antisymmetric exchange contributions. This Gamma-limit corresponds to a micromagnetic energy functional with homogeneous coefficients. We provide explicit formulas for the effective magnetic properties of the composite material in terms of homogenization correctors. Additionally, the variational analysis of the two exchange energy terms is performed in the more general setting of functionals defined on manifold-valued maps with Sobolev regularity, in the case in which the target manifold is a bounded, orientable smooth surface with tubular neighborhood of uniform thickness. Eventually, we present an explicit characterization of minimizers of the effective exchange in the case of magnetic multilayers, providing quantitative evidence of Dzyaloshinskii’s predictions on the emergence of helical structures in composite ferromagnetic materials with stochastic microstructure."}],"_id":"14884","date_updated":"2025-09-04T11:54:01Z","language":[{"iso":"eng"}],"quality_controlled":"1","external_id":{"isi":["001147480200001"],"arxiv":["2306.05151"]},"acknowledgement":"All authors acknowledge support of the Austrian Science Fund (FWF) through the SFB project F65. The research of E. Davoli and L. D’Elia has additionally been supported by the FWF through grants V662, Y1292, and P35359, as well as from OeAD through the WTZ grant CZ09/2023.","day":"23","status":"public","arxiv":1,"publication_identifier":{"eissn":["1432-1467"],"issn":["0938-8974"]},"publication":"Journal of Nonlinear Science","volume":34,"publisher":"Springer Nature","publication_status":"published","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2306.05151","open_access":"1"}],"doi":"10.1007/s00332-023-10005-3","project":[{"_id":"fc31cba2-9c52-11eb-aca3-ff467d239cd2","name":"Taming Complexity in Partial Differential Systems","grant_number":"F6504"}],"month":"01"},{"external_id":{"isi":["001146838000001"]},"ddc":["550"],"acknowledgement":"This project has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No. 101026058. The authors acknowledge the invaluable field assistance of Marta Corrà, Achille Jouberton, Marin Kneib, Stefan Fugger, Celine Ducret and Alexander Groos. The authors would also like to thank Luca Carturan for advice regarding AWS setup and maintenance and Simone Fatichi for provision and support in the use of the Tethys-Chloris model. Open access funding provided by ETH-Bereich Forschungsanstalten.","quality_controlled":"1","file":[{"file_id":"14943","date_created":"2024-02-06T08:38:27Z","relation":"main_file","file_name":"2024_JGRAtmospheres_Shaw.pdf","access_level":"open_access","success":1,"file_size":7481087,"content_type":"application/pdf","checksum":"cad5b93caadb40c14e5faedc34f7bba7","date_updated":"2024-02-06T08:38:27Z","creator":"dernst"}],"publication_identifier":{"eissn":["2169-8996"],"issn":["2169-897X"]},"day":"28","status":"public","publisher":"Wiley","publication_status":"published","publication":"Journal of Geophysical Research: Atmospheres","volume":129,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"corr_author":"1","doi":"10.1029/2023JD040214","file_date_updated":"2024-02-06T08:38:27Z","month":"01","article_type":"original","related_material":{"record":[{"relation":"research_data","id":"14919","status":"public"}]},"intvolume":"       129","author":[{"full_name":"Shaw, Thomas","id":"3caa3f91-1f03-11ee-96ce-e0e553054d6e","orcid":"0000-0001-7640-6152","last_name":"Shaw","first_name":"Thomas"},{"last_name":"Buri","first_name":"Pascal","id":"317987aa-9421-11ee-ac5a-b941b041abba","full_name":"Buri, Pascal"},{"last_name":"Mccarthy","first_name":"Michael","id":"22a2674a-61ce-11ee-94b5-d18813baf16f","full_name":"Mccarthy, Michael"},{"full_name":"Miles, Evan S.","first_name":"Evan S.","last_name":"Miles"},{"id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","full_name":"Pellicciotti, Francesca","first_name":"Francesca","orcid":"0000-0002-5554-8087","last_name":"Pellicciotti"}],"year":"2024","article_processing_charge":"Yes (in subscription journal)","scopus_import":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"Local controls on near-surface glacier cooling under warm atmospheric conditions","isi":1,"oa":1,"issue":"2","type":"journal_article","article_number":"e2023JD040214","date_created":"2024-01-28T23:01:42Z","oa_version":"Published Version","has_accepted_license":"1","language":[{"iso":"eng"}],"department":[{"_id":"FrPe"}],"date_published":"2024-01-28T00:00:00Z","citation":{"apa":"Shaw, T., Buri, P., McCarthy, M., Miles, E. S., &#38; Pellicciotti, F. (2024). Local controls on near-surface glacier cooling under warm atmospheric conditions. <i>Journal of Geophysical Research: Atmospheres</i>. Wiley. <a href=\"https://doi.org/10.1029/2023JD040214\">https://doi.org/10.1029/2023JD040214</a>","mla":"Shaw, Thomas, et al. “Local Controls on Near-Surface Glacier Cooling under Warm Atmospheric Conditions.” <i>Journal of Geophysical Research: Atmospheres</i>, vol. 129, no. 2, e2023JD040214, Wiley, 2024, doi:<a href=\"https://doi.org/10.1029/2023JD040214\">10.1029/2023JD040214</a>.","short":"T. Shaw, P. Buri, M. McCarthy, E.S. Miles, F. Pellicciotti, Journal of Geophysical Research: Atmospheres 129 (2024).","ieee":"T. Shaw, P. Buri, M. McCarthy, E. S. Miles, and F. Pellicciotti, “Local controls on near-surface glacier cooling under warm atmospheric conditions,” <i>Journal of Geophysical Research: Atmospheres</i>, vol. 129, no. 2. Wiley, 2024.","ama":"Shaw T, Buri P, McCarthy M, Miles ES, Pellicciotti F. Local controls on near-surface glacier cooling under warm atmospheric conditions. <i>Journal of Geophysical Research: Atmospheres</i>. 2024;129(2). doi:<a href=\"https://doi.org/10.1029/2023JD040214\">10.1029/2023JD040214</a>","chicago":"Shaw, Thomas, Pascal Buri, Michael McCarthy, Evan S. Miles, and Francesca Pellicciotti. “Local Controls on Near-Surface Glacier Cooling under Warm Atmospheric Conditions.” <i>Journal of Geophysical Research: Atmospheres</i>. Wiley, 2024. <a href=\"https://doi.org/10.1029/2023JD040214\">https://doi.org/10.1029/2023JD040214</a>.","ista":"Shaw T, Buri P, McCarthy M, Miles ES, Pellicciotti F. 2024. Local controls on near-surface glacier cooling under warm atmospheric conditions. Journal of Geophysical Research: Atmospheres. 129(2), e2023JD040214."},"date_updated":"2025-09-04T11:58:38Z","_id":"14885","abstract":[{"text":"The near-surface boundary layer can mediate the response of mountain glaciers to external climate, cooling the overlying air and promoting a density-driven glacier wind. The fundamental processes are conceptually well understood, though the magnitudes of cooling and presence of glacier winds are poorly quantified in space and time, increasing the forcing uncertainty for melt models. We utilize a new data set of on-glacier meteorological measurements on three neighboring glaciers in the Swiss Alps to explore their distinct response to regional climate under the extreme 2022 summer. We find that synoptic wind origins and local terrain modifications, not only glacier size, play an important role in the ability of a glacier to cool the near-surface air. Warm air intrusions from valley or synoptically-driven winds onto the glacier can occur between ∼19% and 64% of the time and contribute between 3% and 81% of the total sensible heat flux to the surface during warm afternoon hours, depending on the fetch of the glacier flowline and its susceptibility to boundary layer erosion. In the context of extreme summer warmth, indicative of future conditions, the boundary layer cooling (up to 6.5°C cooler than its surroundings) and resultant katabatic wind flow are highly heterogeneous between the study glaciers, highlighting the complex and likely non-linear response of glaciers to an uncertain future.","lang":"eng"}]},{"quality_controlled":"1","acknowledgement":"The work was supported by the Institute of Science and Technology Austria (ISTA). We thank Prof. John M. Dudley, Dr. Ugur Sezer, and Dr. Artem Volosniev for valuable discussions.","ddc":["530"],"APC_amount":"2982,14 EUR","status":"public","day":"11","publication_identifier":{"eissn":["2643-1564"]},"file":[{"date_created":"2024-01-31T11:59:30Z","relation":"main_file","file_id":"14918","creator":"dernst","date_updated":"2024-01-31T11:59:30Z","checksum":"42d58f93ae74e7f2c4de058ef75ff8b2","content_type":"application/pdf","file_size":2863627,"success":1,"access_level":"open_access","file_name":"2024_PhysicalReviewResearch_Lorenc.pdf"}],"volume":6,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"publication":"Physical Review Research","publication_status":"published","publisher":"American Physical Society","corr_author":"1","OA_place":"publisher","file_date_updated":"2024-01-31T11:59:30Z","doi":"10.1103/PhysRevResearch.6.013042","OA_type":"gold","month":"01","intvolume":"         6","author":[{"last_name":"Lorenc","first_name":"Dusan","full_name":"Lorenc, Dusan","id":"40D8A3E6-F248-11E8-B48F-1D18A9856A87"},{"orcid":"0000-0002-7183-5203","last_name":"Alpichshev","first_name":"Zhanybek","full_name":"Alpichshev, Zhanybek","id":"45E67A2A-F248-11E8-B48F-1D18A9856A87"}],"article_type":"original","article_processing_charge":"Yes","year":"2024","title":"Dispersive effects in ultrafast nonlinear phenomena: The case of optical Kerr effect","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","scopus_import":"1","issue":"1","oa":1,"oa_version":"Published Version","date_created":"2024-01-28T23:01:42Z","article_number":"013042","type":"journal_article","abstract":[{"text":"It is a basic principle that an effect cannot come before the cause. Dispersive relations that follow from this fundamental fact have proven to be an indispensable tool in physics and engineering. They are most powerful in the domain of linear response where they are known as Kramers-Kronig relations. However, when it comes to nonlinear phenomena the implications of causality are much less explored, apart from several notable exceptions. Here in this paper we demonstrate how to apply the dispersive formalism to analyze the ultrafast nonlinear response in the context of the paradigmatic nonlinear Kerr effect. We find that the requirement of causality introduces a noticeable effect even under assumption that Kerr effect is mediated by quasi-instantaneous off-resonant electronic hyperpolarizability. We confirm this by experimentally measuring the time-resolved Kerr dynamics in GaAs by means of a hybrid pump-probe Mach-Zehnder interferometer and demonstrate the presence of an intrinsic lagging between amplitude and phase responses as predicted by dispersive analysis. Our results describe a general property of the time-resolved nonlinear processes thereby highlighting the importance of accounting for dispersive effects in the nonlinear optical processes involving ultrashort pulses.","lang":"eng"}],"_id":"14886","date_updated":"2025-05-08T10:16:34Z","DOAJ_listed":"1","department":[{"_id":"ZhAl"}],"citation":{"ama":"Lorenc D, Alpichshev Z. Dispersive effects in ultrafast nonlinear phenomena: The case of optical Kerr effect. <i>Physical Review Research</i>. 2024;6(1). doi:<a href=\"https://doi.org/10.1103/PhysRevResearch.6.013042\">10.1103/PhysRevResearch.6.013042</a>","ieee":"D. Lorenc and Z. Alpichshev, “Dispersive effects in ultrafast nonlinear phenomena: The case of optical Kerr effect,” <i>Physical Review Research</i>, vol. 6, no. 1. American Physical Society, 2024.","chicago":"Lorenc, Dusan, and Zhanybek Alpichshev. “Dispersive Effects in Ultrafast Nonlinear Phenomena: The Case of Optical Kerr Effect.” <i>Physical Review Research</i>. American Physical Society, 2024. <a href=\"https://doi.org/10.1103/PhysRevResearch.6.013042\">https://doi.org/10.1103/PhysRevResearch.6.013042</a>.","ista":"Lorenc D, Alpichshev Z. 2024. Dispersive effects in ultrafast nonlinear phenomena: The case of optical Kerr effect. Physical Review Research. 6(1), 013042.","apa":"Lorenc, D., &#38; Alpichshev, Z. (2024). Dispersive effects in ultrafast nonlinear phenomena: The case of optical Kerr effect. <i>Physical Review Research</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevResearch.6.013042\">https://doi.org/10.1103/PhysRevResearch.6.013042</a>","short":"D. Lorenc, Z. Alpichshev, Physical Review Research 6 (2024).","mla":"Lorenc, Dusan, and Zhanybek Alpichshev. “Dispersive Effects in Ultrafast Nonlinear Phenomena: The Case of Optical Kerr Effect.” <i>Physical Review Research</i>, vol. 6, no. 1, 013042, American Physical Society, 2024, doi:<a href=\"https://doi.org/10.1103/PhysRevResearch.6.013042\">10.1103/PhysRevResearch.6.013042</a>."},"date_published":"2024-01-11T00:00:00Z","language":[{"iso":"eng"}],"has_accepted_license":"1"},{"file":[{"file_id":"17268","date_created":"2024-07-16T12:15:19Z","relation":"main_file","file_size":15830346,"file_name":"2024_NatureNeuroscience_FeitosaTome.pdf","access_level":"open_access","success":1,"creator":"dernst","date_updated":"2024-07-16T12:15:19Z","content_type":"application/pdf","checksum":"c509fcad757e4c1c153e857e55c20083"}],"publication_identifier":{"issn":["1097-6256"],"eissn":["1546-1726"]},"pmid":1,"day":"01","status":"public","publisher":"Springer Nature","publication_status":"published","publication":"Nature Neuroscience","volume":27,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"ddc":["570"],"external_id":{"isi":["001145442300001"],"pmid":["38243089"]},"acknowledgement":"We thank S. Erisken from Inscopix for helping us establish in vivo one-photon calcium imaging for this work. We thank K. Su at Tsinghua University for assistance with this work. This work was funded by the President’s PhD Scholarship from Imperial College London (D.F.T.), the Wellcome Trust (225412/Z/22/Z) (S.S.), the Biotechnology and Biological Sciences Research Council (BB/N013956/1 and BB/N019008/1) (C.C.), the Wellcome Trust (200790/Z/16/Z) (C.C.), the Simons Foundation (564408) (C.C.) and the Engineering and Physical Sciences Research Council (EP/R035806/1) (CC). The School of Life Sciences and the IDG/McGovern Institute for Brain Research supported Y.Z. The Warren Alpert Distinguished Scholar Award and National Institutes of Health 1K99NS125131-01 supported D.S.R.","quality_controlled":"1","doi":"10.1038/s41593-023-01551-w","file_date_updated":"2024-07-16T12:15:19Z","month":"03","corr_author":"1","scopus_import":"1","title":"Dynamic and selective engrams emerge with memory consolidation","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_type":"original","related_material":{"record":[{"status":"public","id":"14892","relation":"research_data"}]},"author":[{"full_name":"Feitosa Tomé, Douglas","id":"0eed2d40-3d48-11ec-8d38-f789cc2e40b2","first_name":"Douglas","last_name":"Feitosa Tomé"},{"full_name":"Zhang, Ying","last_name":"Zhang","first_name":"Ying"},{"last_name":"Aida","first_name":"Tomomi","full_name":"Aida, Tomomi"},{"full_name":"Mosto, Olivia","first_name":"Olivia","last_name":"Mosto"},{"full_name":"Lu, Yifeng","first_name":"Yifeng","last_name":"Lu"},{"full_name":"Chen, Mandy","last_name":"Chen","first_name":"Mandy"},{"full_name":"Sadeh, Sadra","last_name":"Sadeh","first_name":"Sadra"},{"full_name":"Roy, Dheeraj S.","first_name":"Dheeraj S.","last_name":"Roy"},{"first_name":"Claudia","last_name":"Clopath","full_name":"Clopath, Claudia"}],"intvolume":"        27","year":"2024","article_processing_charge":"Yes (in subscription journal)","has_accepted_license":"1","language":[{"iso":"eng"}],"citation":{"chicago":"Feitosa Tomé, Douglas, Ying Zhang, Tomomi Aida, Olivia Mosto, Yifeng Lu, Mandy Chen, Sadra Sadeh, Dheeraj S. Roy, and Claudia Clopath. “Dynamic and Selective Engrams Emerge with Memory Consolidation.” <i>Nature Neuroscience</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1038/s41593-023-01551-w\">https://doi.org/10.1038/s41593-023-01551-w</a>.","ista":"Feitosa Tomé D, Zhang Y, Aida T, Mosto O, Lu Y, Chen M, Sadeh S, Roy DS, Clopath C. 2024. Dynamic and selective engrams emerge with memory consolidation. Nature Neuroscience. 27, 561–572.","ieee":"D. Feitosa Tomé <i>et al.</i>, “Dynamic and selective engrams emerge with memory consolidation,” <i>Nature Neuroscience</i>, vol. 27. Springer Nature, pp. 561–572, 2024.","ama":"Feitosa Tomé D, Zhang Y, Aida T, et al. Dynamic and selective engrams emerge with memory consolidation. <i>Nature Neuroscience</i>. 2024;27:561-572. doi:<a href=\"https://doi.org/10.1038/s41593-023-01551-w\">10.1038/s41593-023-01551-w</a>","apa":"Feitosa Tomé, D., Zhang, Y., Aida, T., Mosto, O., Lu, Y., Chen, M., … Clopath, C. (2024). Dynamic and selective engrams emerge with memory consolidation. <i>Nature Neuroscience</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41593-023-01551-w\">https://doi.org/10.1038/s41593-023-01551-w</a>","mla":"Feitosa Tomé, Douglas, et al. “Dynamic and Selective Engrams Emerge with Memory Consolidation.” <i>Nature Neuroscience</i>, vol. 27, Springer Nature, 2024, pp. 561–72, doi:<a href=\"https://doi.org/10.1038/s41593-023-01551-w\">10.1038/s41593-023-01551-w</a>.","short":"D. Feitosa Tomé, Y. Zhang, T. Aida, O. Mosto, Y. Lu, M. Chen, S. Sadeh, D.S. Roy, C. Clopath, Nature Neuroscience 27 (2024) 561–572."},"date_published":"2024-03-01T00:00:00Z","page":"561-572","department":[{"_id":"TiVo"}],"_id":"14887","abstract":[{"text":"Episodic memories are encoded by experience-activated neuronal ensembles that remain necessary and sufficient for recall. However, the temporal evolution of memory engrams after initial encoding is unclear. In this study, we employed computational and experimental approaches to examine how the neural composition and selectivity of engrams change with memory consolidation. Our spiking neural network model yielded testable predictions: memories transition from unselective to selective as neurons drop out of and drop into engrams; inhibitory activity during recall is essential for memory selectivity; and inhibitory synaptic plasticity during memory consolidation is critical for engrams to become selective. Using activity-dependent labeling, longitudinal calcium imaging and a combination of optogenetic and chemogenetic manipulations in mouse dentate gyrus, we conducted contextual fear conditioning experiments that supported our model’s predictions. Our results reveal that memory engrams are dynamic and that changes in engram composition mediated by inhibitory plasticity are crucial for the emergence of memory selectivity.","lang":"eng"}],"date_updated":"2025-04-23T07:40:21Z","isi":1,"oa":1,"type":"journal_article","oa_version":"Published Version","date_created":"2024-01-28T23:01:43Z"},{"author":[{"last_name":"De Nooijer","first_name":"Phoebe","full_name":"De Nooijer, Phoebe"},{"first_name":"Soeren","last_name":"Terziadis","full_name":"Terziadis, Soeren"},{"first_name":"Alexandra","last_name":"Weinberger","full_name":"Weinberger, Alexandra"},{"id":"45CFE238-F248-11E8-B48F-1D18A9856A87","full_name":"Masárová, Zuzana","orcid":"0000-0002-6660-1322","last_name":"Masárová","first_name":"Zuzana"},{"full_name":"Mchedlidze, Tamara","last_name":"Mchedlidze","first_name":"Tamara"},{"full_name":"Löffler, Maarten","last_name":"Löffler","first_name":"Maarten"},{"full_name":"Rote, Günter","last_name":"Rote","first_name":"Günter"}],"intvolume":"     14466","year":"2024","article_processing_charge":"No","conference":{"location":"Isola delle Femmine, Palermo, Italy","start_date":"2023-09-20","end_date":"2023-09-22","name":"GD: Graph Drawing and Network Visualization"},"title":"Removing popular faces in curve arrangements","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","scopus_import":"1","alternative_title":["LNCS"],"isi":1,"oa":1,"oa_version":"Preprint","date_created":"2024-01-28T23:01:43Z","type":"conference","page":"18-33","date_published":"2024-01-06T00:00:00Z","citation":{"ista":"De Nooijer P, Terziadis S, Weinberger A, Masárová Z, Mchedlidze T, Löffler M, Rote G. 2024. Removing popular faces in curve arrangements. 31st International Symposium on Graph Drawing and Network Visualization. GD: Graph Drawing and Network Visualization, LNCS, vol. 14466, 18–33.","chicago":"De Nooijer, Phoebe, Soeren Terziadis, Alexandra Weinberger, Zuzana Masárová, Tamara Mchedlidze, Maarten Löffler, and Günter Rote. “Removing Popular Faces in Curve Arrangements.” In <i>31st International Symposium on Graph Drawing and Network Visualization</i>, 14466:18–33. Springer Nature, 2024. <a href=\"https://doi.org/10.1007/978-3-031-49275-4_2\">https://doi.org/10.1007/978-3-031-49275-4_2</a>.","ama":"De Nooijer P, Terziadis S, Weinberger A, et al. Removing popular faces in curve arrangements. In: <i>31st International Symposium on Graph Drawing and Network Visualization</i>. Vol 14466. Springer Nature; 2024:18-33. doi:<a href=\"https://doi.org/10.1007/978-3-031-49275-4_2\">10.1007/978-3-031-49275-4_2</a>","ieee":"P. De Nooijer <i>et al.</i>, “Removing popular faces in curve arrangements,” in <i>31st International Symposium on Graph Drawing and Network Visualization</i>, Isola delle Femmine, Palermo, Italy, 2024, vol. 14466, pp. 18–33.","short":"P. De Nooijer, S. Terziadis, A. Weinberger, Z. Masárová, T. Mchedlidze, M. Löffler, G. Rote, in:, 31st International Symposium on Graph Drawing and Network Visualization, Springer Nature, 2024, pp. 18–33.","mla":"De Nooijer, Phoebe, et al. “Removing Popular Faces in Curve Arrangements.” <i>31st International Symposium on Graph Drawing and Network Visualization</i>, vol. 14466, Springer Nature, 2024, pp. 18–33, doi:<a href=\"https://doi.org/10.1007/978-3-031-49275-4_2\">10.1007/978-3-031-49275-4_2</a>.","apa":"De Nooijer, P., Terziadis, S., Weinberger, A., Masárová, Z., Mchedlidze, T., Löffler, M., &#38; Rote, G. (2024). Removing popular faces in curve arrangements. In <i>31st International Symposium on Graph Drawing and Network Visualization</i> (Vol. 14466, pp. 18–33). Isola delle Femmine, Palermo, Italy: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-031-49275-4_2\">https://doi.org/10.1007/978-3-031-49275-4_2</a>"},"department":[{"_id":"UlWa"},{"_id":"HeEd"}],"_id":"14888","abstract":[{"lang":"eng","text":"A face in a curve arrangement is called popular if it is bounded by the same curve multiple times. Motivated by the automatic generation of curved nonogram puzzles, we investigate possibilities to eliminate the popular faces in an arrangement by inserting a single additional curve. This turns out to be NP-hard; however, it becomes tractable when the number of popular faces is small: We present a probabilistic FPT-approach in the number of popular faces."}],"date_updated":"2025-09-04T11:52:35Z","language":[{"iso":"eng"}],"quality_controlled":"1","external_id":{"isi":["001207942000002"],"arxiv":["2202.12175"]},"acknowledgement":"This work was initiated at the 16th European Research Week on Geometric Graphs in Strobl in 2019. A.W. is supported by the Austrian Science Fund (FWF): W1230. S.T. has been funded by the Vienna Science and Technology Fund (WWTF) [10.47379/ICT19035]. A preliminary version of this work has been presented at the 38th European Workshop on Computational Geometry (EuroCG 2022) in Perugia [9]. A full version of this paper, which includes appendices but is otherwise identical, is available as a technical report [10].","day":"06","status":"public","arxiv":1,"publication_identifier":{"isbn":["9783031492747"],"issn":["0302-9743"],"eissn":["1611-3349"]},"publication":"31st International Symposium on Graph Drawing and Network Visualization","volume":14466,"publisher":"Springer Nature","publication_status":"published","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2202.12175","open_access":"1"}],"doi":"10.1007/978-3-031-49275-4_2","month":"01"}]