[{"language":[{"iso":"eng"}],"publication":"bioRxiv","project":[{"name":"Causes and consequences of population fragmentation","_id":"c08d3278-5a5b-11eb-8a69-fdb09b55f4b8","grant_number":"P32896"},{"name":"The impact of deleterious mutations on small populations","_id":"34d33d68-11ca-11ed-8bc3-ec13763c0ca8","grant_number":"26293"},{"grant_number":"26380","name":"Polygenic Adaptation in a Metapopulation","_id":"34c872fe-11ca-11ed-8bc3-8534b82131e6"}],"date_created":"2024-01-04T09:35:54Z","status":"public","day":"04","oa_version":"Preprint","abstract":[{"lang":"eng","text":"Fragmented landscapes pose a significant threat to the persistence of species as they are highly susceptible to heightened risk of extinction due to the combined effects of genetic and demographic factors such as genetic drift and demographic stochasticity. This paper explores the intricate interplay between genetic load and extinction risk within metapopulations with a focus on understanding the impact of eco-evolutionary feedback mechanisms. We distinguish between two models of selection: soft selection, characterised by subpopulations maintaining carrying capacity despite load, and hard selection, where load can significantly affect population size. Within the soft selection framework, we investigate the impact of gene flow on genetic load at a single locus, while also considering the effect of selection strength and dominance coefficient. We subsequently build on this to examine how gene flow influences both population size and load under hard selection as well as identify critical thresholds for metapopulation persistence. Our analysis employs the diffusion, semi-deterministic and effective migration approximations. Our findings reveal that under soft selection, even modest levels of migration can significantly alleviate the burden of load. In sharp contrast, with hard selection, a much higher degree of gene flow is required to mitigate load and prevent the collapse of the metapopulation. Overall, this study sheds light into the crucial role migration plays in shaping the dynamics of genetic load and extinction risk in fragmented landscapes, offering valuable insights for conservation strategies and the preservation of diversity in a changing world."}],"main_file_link":[{"url":"https://www.biorxiv.org/content/10.1101/2023.12.02.569702v1","open_access":"1"}],"doi":"10.1101/2023.12.02.569702","article_processing_charge":"No","publication_status":"draft","OA_place":"repository","_id":"14732","citation":{"apa":"Olusanya, O. O., Khudiakova, K., &#38; Sachdeva, H. (n.d.). Genetic load, eco-evolutionary feedback and extinction in a metapopulation. <i>bioRxiv</i>. <a href=\"https://doi.org/10.1101/2023.12.02.569702\">https://doi.org/10.1101/2023.12.02.569702</a>","short":"O.O. Olusanya, K. Khudiakova, H. Sachdeva, BioRxiv (n.d.).","chicago":"Olusanya, Oluwafunmilola O, Kseniia Khudiakova, and Himani Sachdeva. “Genetic Load, Eco-Evolutionary Feedback and Extinction in a Metapopulation.” <i>BioRxiv</i>, n.d. <a href=\"https://doi.org/10.1101/2023.12.02.569702\">https://doi.org/10.1101/2023.12.02.569702</a>.","ama":"Olusanya OO, Khudiakova K, Sachdeva H. Genetic load, eco-evolutionary feedback and extinction in a metapopulation. <i>bioRxiv</i>. doi:<a href=\"https://doi.org/10.1101/2023.12.02.569702\">10.1101/2023.12.02.569702</a>","ista":"Olusanya OO, Khudiakova K, Sachdeva H. Genetic load, eco-evolutionary feedback and extinction in a metapopulation. bioRxiv, <a href=\"https://doi.org/10.1101/2023.12.02.569702\">10.1101/2023.12.02.569702</a>.","mla":"Olusanya, Oluwafunmilola O., et al. “Genetic Load, Eco-Evolutionary Feedback and Extinction in a Metapopulation.” <i>BioRxiv</i>, doi:<a href=\"https://doi.org/10.1101/2023.12.02.569702\">10.1101/2023.12.02.569702</a>.","ieee":"O. O. Olusanya, K. Khudiakova, and H. Sachdeva, “Genetic load, eco-evolutionary feedback and extinction in a metapopulation,” <i>bioRxiv</i>. ."},"year":"2023","date_published":"2023-12-04T00:00:00Z","oa":1,"related_material":{"record":[{"relation":"later_version","status":"public","id":"21322"},{"id":"14711","status":"public","relation":"dissertation_contains"}]},"type":"preprint","author":[{"orcid":"0000-0003-1971-8314","first_name":"Oluwafunmilola O","full_name":"Olusanya, Oluwafunmilola O","id":"41AD96DC-F248-11E8-B48F-1D18A9856A87","last_name":"Olusanya"},{"id":"4E6DC800-AE37-11E9-AC72-31CAE5697425","full_name":"Khudiakova, Kseniia","last_name":"Khudiakova","first_name":"Kseniia","orcid":"0000-0002-6246-1465"},{"id":"42377A0A-F248-11E8-B48F-1D18A9856A87","full_name":"Sachdeva, Himani","last_name":"Sachdeva","first_name":"Himani"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Genetic load, eco-evolutionary feedback and extinction in a metapopulation","month":"12","department":[{"_id":"NiBa"},{"_id":"JaMa"}],"date_updated":"2026-04-07T12:54:28Z","corr_author":"1","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"}},{"article_type":"original","abstract":[{"lang":"eng","text":"Regulation of the Arp2/3 complex is required for productive nucleation of branched actin networks. An emerging aspect of regulation is the incorporation of subunit isoforms into the Arp2/3 complex. Specifically, both ArpC5 subunit isoforms, ArpC5 and ArpC5L, have been reported to fine-tune nucleation activity and branch junction stability. We have combined reverse genetics and cellular structural biology to describe how ArpC5 and ArpC5L differentially affect cell migration. Both define the structural stability of ArpC1 in branch junctions and, in turn, by determining protrusion characteristics, affect protein dynamics and actin network ultrastructure. ArpC5 isoforms also affect the positioning of members of the Ena/Vasodilator-stimulated phosphoprotein (VASP) family of actin filament elongators, which mediate ArpC5 isoform–specific effects on the actin assembly level. Our results suggest that ArpC5 and Ena/VASP proteins are part of a signaling pathway enhancing cell migration.</jats:p>"}],"project":[{"grant_number":"P33367","name":"Structure and isoform diversity of the Arp2/3 complex","_id":"9B954C5C-BA93-11EA-9121-9846C619BF3A"}],"quality_controlled":"1","external_id":{"pmid":["36662867"],"isi":["000964550100015"]},"oa_version":"Published Version","day":"20","volume":9,"article_number":"add6495","isi":1,"title":"ArpC5 isoforms regulate Arp2/3 complex–dependent protrusion through differential Ena/VASP positioning","department":[{"_id":"FlSc"},{"_id":"EM-Fac"}],"month":"01","date_updated":"2026-04-07T12:59:44Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"doi":"10.1126/sciadv.add6495","article_processing_charge":"No","publisher":"American Association for the Advancement of Science","publication_identifier":{"issn":["2375-2548"]},"publication_status":"published","citation":{"short":"F. Fäßler, M. Javoor, J. Datler, H. Döring, F. Hofer, G.A. Dimchev, V.-V. Hodirnau, J. Faix, K. Rottner, F.K. Schur, Science Advances 9 (2023).","apa":"Fäßler, F., Javoor, M., Datler, J., Döring, H., Hofer, F., Dimchev, G. A., … Schur, F. K. (2023). ArpC5 isoforms regulate Arp2/3 complex–dependent protrusion through differential Ena/VASP positioning. <i>Science Advances</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/sciadv.add6495\">https://doi.org/10.1126/sciadv.add6495</a>","ama":"Fäßler F, Javoor M, Datler J, et al. ArpC5 isoforms regulate Arp2/3 complex–dependent protrusion through differential Ena/VASP positioning. <i>Science Advances</i>. 2023;9(3). doi:<a href=\"https://doi.org/10.1126/sciadv.add6495\">10.1126/sciadv.add6495</a>","chicago":"Fäßler, Florian, Manjunath Javoor, Julia Datler, Hermann Döring, Florian Hofer, Georgi A Dimchev, Victor-Valentin Hodirnau, Jan Faix, Klemens Rottner, and Florian KM Schur. “ArpC5 Isoforms Regulate Arp2/3 Complex–Dependent Protrusion through Differential Ena/VASP Positioning.” <i>Science Advances</i>. American Association for the Advancement of Science, 2023. <a href=\"https://doi.org/10.1126/sciadv.add6495\">https://doi.org/10.1126/sciadv.add6495</a>.","ista":"Fäßler F, Javoor M, Datler J, Döring H, Hofer F, Dimchev GA, Hodirnau V-V, Faix J, Rottner K, Schur FK. 2023. ArpC5 isoforms regulate Arp2/3 complex–dependent protrusion through differential Ena/VASP positioning. Science Advances. 9(3), add6495.","ieee":"F. Fäßler <i>et al.</i>, “ArpC5 isoforms regulate Arp2/3 complex–dependent protrusion through differential Ena/VASP positioning,” <i>Science Advances</i>, vol. 9, no. 3. American Association for the Advancement of Science, 2023.","mla":"Fäßler, Florian, et al. “ArpC5 Isoforms Regulate Arp2/3 Complex–Dependent Protrusion through Differential Ena/VASP Positioning.” <i>Science Advances</i>, vol. 9, no. 3, add6495, American Association for the Advancement of Science, 2023, doi:<a href=\"https://doi.org/10.1126/sciadv.add6495\">10.1126/sciadv.add6495</a>."},"date_published":"2023-01-20T00:00:00Z","year":"2023","pmid":1,"intvolume":"         9","ddc":["570"],"file":[{"success":1,"access_level":"open_access","file_size":1756234,"relation":"main_file","date_created":"2023-01-23T07:45:54Z","checksum":"ce81a6d0b84170e5e8c62f6acfa15d9e","creator":"dernst","file_id":"12335","date_updated":"2023-01-23T07:45:54Z","file_name":"2023_ScienceAdvances_Faessler.pdf","content_type":"application/pdf"}],"language":[{"iso":"eng"}],"publication":"Science Advances","acknowledged_ssus":[{"_id":"ScienComp"},{"_id":"LifeSc"},{"_id":"Bio"},{"_id":"EM-Fac"}],"has_accepted_license":"1","scopus_import":"1","date_created":"2023-01-23T07:26:42Z","status":"public","keyword":["Multidisciplinary"],"type":"journal_article","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledgement":"We would like to thank K. von Peinen and B. Denker (Helmholtz Centre for Infection Research, Braunschweig, Germany) for experimental and technical assistance, respectively.\r\nThis research was supported by the Scientific Service Units (SSUs) of ISTA through resources provided by Scientific Computing (SciComp), the Life Science Facility (LSF), the Imaging and Optics facility (IOF), and the Electron Microscopy Facility (EMF). We acknowledge support from ISTA and from the Austrian Science Fund (FWF) (P33367) to F.K.M.S., from the Research Training Group GRK2223 and the Helmholtz Society to K.R,. and from the Deutsche Forschungsgemeinschaft (DFG) to J.F. and K.R.","author":[{"orcid":"0000-0001-7149-769X","first_name":"Florian","last_name":"Fäßler","id":"404F5528-F248-11E8-B48F-1D18A9856A87","full_name":"Fäßler, Florian"},{"last_name":"Javoor","id":"305ab18b-dc7d-11ea-9b2f-b58195228ea2","full_name":"Javoor, Manjunath","orcid":"0000-0003-2311-2112","first_name":"Manjunath"},{"first_name":"Julia","orcid":"0000-0002-3616-8580","last_name":"Datler","id":"3B12E2E6-F248-11E8-B48F-1D18A9856A87","full_name":"Datler, Julia"},{"last_name":"Döring","full_name":"Döring, Hermann","first_name":"Hermann"},{"last_name":"Hofer","id":"b9d234ba-9e33-11ed-95b6-cd561df280e6","full_name":"Hofer, Florian","first_name":"Florian"},{"last_name":"Dimchev","full_name":"Dimchev, Georgi A","id":"38C393BE-F248-11E8-B48F-1D18A9856A87","first_name":"Georgi A","orcid":"0000-0001-8370-6161"},{"full_name":"Hodirnau, Victor-Valentin","id":"3661B498-F248-11E8-B48F-1D18A9856A87","last_name":"Hodirnau","first_name":"Victor-Valentin","orcid":"0000-0003-3904-947X"},{"full_name":"Faix, Jan","last_name":"Faix","first_name":"Jan"},{"full_name":"Rottner, Klemens","last_name":"Rottner","first_name":"Klemens"},{"last_name":"Schur","full_name":"Schur, Florian KM","id":"48AD8942-F248-11E8-B48F-1D18A9856A87","first_name":"Florian KM","orcid":"0000-0003-4790-8078"}],"issue":"3","corr_author":"1","file_date_updated":"2023-01-23T07:45:54Z","_id":"12334","oa":1,"related_material":{"record":[{"relation":"research_data","status":"public","id":"14562"},{"relation":"dissertation_contains","id":"18766","status":"public"}]}},{"department":[{"_id":"JaMa"}],"month":"08","date_updated":"2026-04-07T13:00:02Z","corr_author":"1","title":"Contractive coupling rates and curvature lower bounds for Markov chains","type":"preprint","author":[{"first_name":"Francesco","id":"d3ac8ac6-dc8d-11ea-abe3-e2a9628c4c3c","full_name":"Pedrotti, Francesco","last_name":"Pedrotti"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_number":"2308.00516","citation":{"ista":"Pedrotti F. Contractive coupling rates and curvature lower bounds for Markov chains. arXiv, 2308.00516.","mla":"Pedrotti, Francesco. “Contractive Coupling Rates and Curvature Lower Bounds for Markov Chains.” <i>ArXiv</i>, 2308.00516, doi:<a href=\"https://doi.org/10.48550/arXiv.2308.00516\">10.48550/arXiv.2308.00516</a>.","ieee":"F. Pedrotti, “Contractive coupling rates and curvature lower bounds for Markov chains,” <i>arXiv</i>. .","apa":"Pedrotti, F. (n.d.). Contractive coupling rates and curvature lower bounds for Markov chains. <i>arXiv</i>. <a href=\"https://doi.org/10.48550/arXiv.2308.00516\">https://doi.org/10.48550/arXiv.2308.00516</a>","short":"F. Pedrotti, ArXiv (n.d.).","chicago":"Pedrotti, Francesco. “Contractive Coupling Rates and Curvature Lower Bounds for Markov Chains.” <i>ArXiv</i>, n.d. <a href=\"https://doi.org/10.48550/arXiv.2308.00516\">https://doi.org/10.48550/arXiv.2308.00516</a>.","ama":"Pedrotti F. Contractive coupling rates and curvature lower bounds for Markov chains. <i>arXiv</i>. doi:<a href=\"https://doi.org/10.48550/arXiv.2308.00516\">10.48550/arXiv.2308.00516</a>"},"year":"2023","related_material":{"record":[{"relation":"later_version","id":"20040","status":"public"},{"status":"public","id":"17336","relation":"dissertation_contains"}]},"date_published":"2023-08-02T00:00:00Z","oa":1,"publication_status":"draft","OA_place":"repository","_id":"17351","doi":"10.48550/arXiv.2308.00516","arxiv":1,"article_processing_charge":"No","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2308.00516"}],"abstract":[{"lang":"eng","text":"Contractive coupling rates have been recently introduced by Conforti as a\r\ntool to establish convex Sobolev inequalities (including modified log-Sobolev\r\nand Poincar\\'{e} inequality) for some classes of Markov chains. In this work,\r\nwe show how contractive coupling rates can also be used to prove stronger\r\ninequalities, in the form of curvature lower bounds for Markov chains and\r\ngeodesic convexity of entropic functionals. We illustrate this in several\r\nexamples discussed by Conforti, where in particular, after appropriately\r\nchoosing a parameter function, we establish positive curvature in the entropic\r\nand (discrete) Bakry--\\'{E}mery sense. In addition, we recall and give\r\nstraightforward generalizations of some notions of coarse Ricci curvature, and\r\nwe discuss some of their properties and relations with the concepts of\r\ncouplings and coupling rates: as an application, we show exponential\r\ncontraction of the $p$-Wasserstein distance for the heat flow in the\r\naforementioned examples."}],"day":"02","oa_version":"Preprint","date_created":"2024-07-31T08:02:16Z","status":"public","external_id":{"arxiv":["2308.00516"]},"language":[{"iso":"eng"}],"publication":"arXiv"},{"oa":1,"related_material":{"record":[{"relation":"dissertation_contains","id":"17490","status":"public"}]},"arxiv":1,"_id":"14461","corr_author":"1","acknowledgement":"The authors gratefully acknowledge funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 805223 ScaleML), as well as experimental support from the IST Austria IT department, in particular Stefano Elefante, Andrei Hornoiu, and Alois Schloegl. AV acknowledges the support of the French Agence Nationale de la Recherche (ANR), under grant ANR-21-CE48-0016 (project COMCOPT), the support of Fondation Hadamard with a PRMO grant, and the support of CNRS with a CoopIntEER IEA grant (project ALFRED).","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"first_name":"Ilia","last_name":"Markov","full_name":"Markov, Ilia","id":"D0CF4148-C985-11E9-8066-0BDEE5697425"},{"full_name":"Vladu, Adrian","last_name":"Vladu","first_name":"Adrian"},{"last_name":"Guo","full_name":"Guo, Qi","first_name":"Qi"},{"first_name":"Dan-Adrian","orcid":"0000-0003-3650-940X","last_name":"Alistarh","full_name":"Alistarh, Dan-Adrian","id":"4A899BFC-F248-11E8-B48F-1D18A9856A87"}],"type":"conference","scopus_import":"1","date_created":"2023-10-29T23:01:17Z","status":"public","publication":"Proceedings of the 40th International Conference on Machine Learning","language":[{"iso":"eng"}],"acknowledged_ssus":[{"_id":"ScienComp"}],"page":"24020-24044","intvolume":"       202","date_published":"2023-07-30T00:00:00Z","year":"2023","citation":{"chicago":"Markov, Ilia, Adrian Vladu, Qi Guo, and Dan-Adrian Alistarh. “Quantized Distributed Training of Large Models with Convergence Guarantees.” In <i>Proceedings of the 40th International Conference on Machine Learning</i>, 202:24020–44. ML Research Press, 2023.","ama":"Markov I, Vladu A, Guo Q, Alistarh D-A. Quantized distributed training of large models with convergence guarantees. In: <i>Proceedings of the 40th International Conference on Machine Learning</i>. Vol 202. ML Research Press; 2023:24020-24044.","apa":"Markov, I., Vladu, A., Guo, Q., &#38; Alistarh, D.-A. (2023). Quantized distributed training of large models with convergence guarantees. In <i>Proceedings of the 40th International Conference on Machine Learning</i> (Vol. 202, pp. 24020–24044). Honolulu, Hawaii, HI, United States: ML Research Press.","short":"I. Markov, A. Vladu, Q. Guo, D.-A. Alistarh, in:, Proceedings of the 40th International Conference on Machine Learning, ML Research Press, 2023, pp. 24020–24044.","mla":"Markov, Ilia, et al. “Quantized Distributed Training of Large Models with Convergence Guarantees.” <i>Proceedings of the 40th International Conference on Machine Learning</i>, vol. 202, ML Research Press, 2023, pp. 24020–44.","ieee":"I. Markov, A. Vladu, Q. Guo, and D.-A. Alistarh, “Quantized distributed training of large models with convergence guarantees,” in <i>Proceedings of the 40th International Conference on Machine Learning</i>, Honolulu, Hawaii, HI, United States, 2023, vol. 202, pp. 24020–24044.","ista":"Markov I, Vladu A, Guo Q, Alistarh D-A. 2023. Quantized distributed training of large models with convergence guarantees. Proceedings of the 40th International Conference on Machine Learning. ICML: International Conference on Machine Learning, PMLR, vol. 202, 24020–24044."},"article_processing_charge":"No","publisher":"ML Research Press","publication_identifier":{"eissn":["2640-3498"]},"publication_status":"published","date_updated":"2026-04-07T13:00:54Z","month":"07","department":[{"_id":"DaAl"}],"title":"Quantized distributed training of large models with convergence guarantees","ec_funded":1,"volume":202,"day":"30","oa_version":"Preprint","alternative_title":["PMLR"],"quality_controlled":"1","external_id":{"arxiv":["2302.02390"]},"project":[{"call_identifier":"H2020","name":"Elastic Coordination for Scalable Machine Learning","_id":"268A44D6-B435-11E9-9278-68D0E5697425","grant_number":"805223"}],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2302.02390"}],"abstract":[{"lang":"eng","text":"Communication-reduction techniques are a popular way to improve scalability in data-parallel training of deep neural networks (DNNs). The recent emergence of large language models such as GPT has created the need for new approaches to exploit data-parallelism. Among these, fully-sharded data parallel (FSDP) training is highly popular, yet it still encounters scalability bottlenecks. One reason is that applying compression techniques to FSDP is challenging: as the vast majority of the communication involves the model’s weights, direct compression alters convergence and leads to accuracy loss. We present QSDP, a variant of FSDP which supports both gradient and weight quantization with theoretical guarantees, is simple to implement and has essentially no overheads. To derive QSDP we prove that a natural modification of SGD achieves convergence even when we only maintain quantized weights, and thus the domain over which we train consists of quantized points and is, therefore, highly non-convex. We validate this approach by training GPT-family models with up to 1.3 billion parameters on a multi-node cluster. Experiments show that QSDP preserves model accuracy, while completely removing the communication bottlenecks of FSDP, providing end-to-end speedups of up to 2.2x."}],"conference":{"end_date":"2023-07-29","name":"ICML: International Conference on Machine Learning","location":"Honolulu, Hawaii, HI, United States","start_date":"2023-07-23"}},{"article_number":"2310.06677","title":"Prethermalization for deformed Wigner Matrices","month":"12","department":[{"_id":"LaEr"}],"date_updated":"2026-04-07T13:02:12Z","doi":"10.48550/arXiv.2310.06677","article_processing_charge":"No","publication_status":"draft","citation":{"mla":"Erdös, László, et al. “Prethermalization for Deformed Wigner Matrices.” <i>ArXiv</i>, 2310.06677, doi:<a href=\"https://doi.org/10.48550/arXiv.2310.06677\">10.48550/arXiv.2310.06677</a>.","ieee":"L. Erdös, S. J. Henheik, J. Reker, and V. Riabov, “Prethermalization for deformed Wigner Matrices,” <i>arXiv</i>. .","ista":"Erdös L, Henheik SJ, Reker J, Riabov V. Prethermalization for deformed Wigner Matrices. arXiv, 2310.06677.","chicago":"Erdös, László, Sven Joscha Henheik, Jana Reker, and Volodymyr Riabov. “Prethermalization for Deformed Wigner Matrices.” <i>ArXiv</i>, n.d. <a href=\"https://doi.org/10.48550/arXiv.2310.06677\">https://doi.org/10.48550/arXiv.2310.06677</a>.","ama":"Erdös L, Henheik SJ, Reker J, Riabov V. Prethermalization for deformed Wigner Matrices. <i>arXiv</i>. doi:<a href=\"https://doi.org/10.48550/arXiv.2310.06677\">10.48550/arXiv.2310.06677</a>","apa":"Erdös, L., Henheik, S. J., Reker, J., &#38; Riabov, V. (n.d.). Prethermalization for deformed Wigner Matrices. <i>arXiv</i>. <a href=\"https://doi.org/10.48550/arXiv.2310.06677\">https://doi.org/10.48550/arXiv.2310.06677</a>","short":"L. Erdös, S.J. Henheik, J. Reker, V. Riabov, ArXiv (n.d.)."},"year":"2023","date_published":"2023-12-23T00:00:00Z","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2310.06677"}],"abstract":[{"lang":"eng","text":"We prove that a class of weakly perturbed Hamiltonians of the form $H_λ= H_0 + λW$, with $W$ being a Wigner matrix, exhibits prethermalization. That is, the time evolution generated by $H_λ$ relaxes to its ultimate thermal state via an intermediate prethermal state with a lifetime of order $λ^{-2}$. Moreover, we obtain a general relaxation formula, expressing the perturbed dynamics via the unperturbed dynamics and the ultimate thermal state. The proof relies on a two-resolvent law for the deformed Wigner matrix $H_λ$."}],"project":[{"_id":"62796744-2b32-11ec-9570-940b20777f1d","name":"Random matrices beyond Wigner-Dyson-Mehta","call_identifier":"H2020","grant_number":"101020331"}],"external_id":{"arxiv":["2310.06677"]},"ec_funded":1,"oa_version":"Preprint","day":"23","type":"preprint","author":[{"full_name":"Erdös, László","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","last_name":"Erdös","orcid":"0000-0001-5366-9603","first_name":"László"},{"full_name":"Henheik, Sven Joscha","id":"31d731d7-d235-11ea-ad11-b50331c8d7fb","last_name":"Henheik","first_name":"Sven Joscha","orcid":"0000-0003-1106-327X"},{"last_name":"Reker","id":"e796e4f9-dc8d-11ea-abe3-97e26a0323e9","full_name":"Reker, Jana","first_name":"Jana"},{"id":"1949f904-edfb-11eb-afb5-e2dfddabb93b","full_name":"Riabov, Volodymyr","last_name":"Riabov","first_name":"Volodymyr"}],"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","corr_author":"1","arxiv":1,"OA_place":"repository","_id":"17174","related_material":{"record":[{"relation":"later_version","id":"18764","status":"public"},{"status":"public","id":"20575","relation":"dissertation_contains"},{"id":"17164","status":"public","relation":"dissertation_contains"}]},"oa":1,"language":[{"iso":"eng"}],"publication":"arXiv","status":"public","date_created":"2024-06-26T08:56:52Z"},{"citation":{"ama":"Reker J. Multi-point functional central limit theorem for Wigner Matrices. <i>arXiv</i>. doi:<a href=\"https://doi.org/10.48550/arXiv.2307.11028\">10.48550/arXiv.2307.11028</a>","chicago":"Reker, Jana. “Multi-Point Functional Central Limit Theorem for Wigner Matrices.” <i>ArXiv</i>, n.d. <a href=\"https://doi.org/10.48550/arXiv.2307.11028\">https://doi.org/10.48550/arXiv.2307.11028</a>.","short":"J. Reker, ArXiv (n.d.).","apa":"Reker, J. (n.d.). Multi-point functional central limit theorem for Wigner Matrices. <i>arXiv</i>. <a href=\"https://doi.org/10.48550/arXiv.2307.11028\">https://doi.org/10.48550/arXiv.2307.11028</a>","ieee":"J. Reker, “Multi-point functional central limit theorem for Wigner Matrices,” <i>arXiv</i>. .","mla":"Reker, Jana. “Multi-Point Functional Central Limit Theorem for Wigner Matrices.” <i>ArXiv</i>, 2307.11028, doi:<a href=\"https://doi.org/10.48550/arXiv.2307.11028\">10.48550/arXiv.2307.11028</a>.","ista":"Reker J. Multi-point functional central limit theorem for Wigner Matrices. arXiv, 2307.11028."},"date_published":"2023-07-21T00:00:00Z","year":"2023","oa":1,"related_material":{"record":[{"relation":"later_version","status":"public","id":"18762"},{"relation":"dissertation_contains","id":"17164","status":"public"}]},"arxiv":1,"doi":"10.48550/arXiv.2307.11028","article_processing_charge":"No","OA_place":"repository","publication_status":"draft","_id":"17173","department":[{"_id":"LaEr"}],"month":"07","date_updated":"2026-04-07T13:02:12Z","type":"preprint","article_number":"2307.11028","author":[{"first_name":"Jana","last_name":"Reker","full_name":"Reker, Jana","id":"e796e4f9-dc8d-11ea-abe3-97e26a0323e9"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Multi-point functional central limit theorem for Wigner Matrices","status":"public","date_created":"2024-06-26T08:54:56Z","day":"21","oa_version":"Preprint","language":[{"iso":"eng"}],"publication":"arXiv","external_id":{"arxiv":["2307.11028"]},"main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2307.11028","open_access":"1"}],"abstract":[{"lang":"eng","text":"Consider the random variable $\\mathrm{Tr}( f_1(W)A_1\\dots f_k(W)A_k)$ where $W$ is an $N\\times N$ Hermitian Wigner matrix, $k\\in\\mathbb{N}$, and choose (possibly $N$-dependent) regular functions $f_1,\\dots, f_k$ as well as bounded deterministic matrices $A_1,\\dots,A_k$. We give a functional central limit theorem showing that the fluctuations around the expectation are Gaussian. Moreover, we determine the limiting covariance structure and give explicit error bounds in terms of the scaling of $f_1,\\dots,f_k$ and the number of traceless matrices among $A_1,\\dots,A_k$, thus extending the results of [Cipolloni, Erdős, Schröder 2023] to products of arbitrary length $k\\geq2$. As an application, we consider the fluctuation of $\\mathrm{Tr}(\\mathrm{e}^{\\mathrm{i} tW}A_1\\mathrm{e}^{-\\mathrm{i} tW}A_2)$ around its thermal value $\\mathrm{Tr}(A_1)\\mathrm{Tr}(A_2)$ when $t$ is large and give an explicit formula for the variance."}]},{"supervisor":[{"id":"2BD278E6-F248-11E8-B48F-1D18A9856A87","full_name":"Jösch, Maximilian A","last_name":"Jösch","orcid":"0000-0002-3937-1330","first_name":"Maximilian A"}],"status":"public","date_created":"2023-03-08T15:19:45Z","acknowledged_ssus":[{"_id":"PreCl"},{"_id":"Bio"},{"_id":"LifeSc"},{"_id":"M-Shop"},{"_id":"CampIT"}],"has_accepted_license":"1","language":[{"iso":"eng"}],"file":[{"creator":"lburnett","file_id":"12717","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","file_name":"Burnett_Thesis_2023.docx","date_updated":"2023-03-08T15:08:46Z","relation":"source_file","file_size":23029260,"access_level":"closed","checksum":"6c6d9cc2c4cdacb74e6b1047a34d7332","date_created":"2023-03-08T15:08:46Z"},{"date_created":"2023-03-08T15:08:46Z","checksum":"cebc77705288bf4382db9b3541483cd0","success":1,"access_level":"open_access","file_size":11959869,"relation":"main_file","file_name":"Burnett_Thesis_2023_pdfA.pdf","date_updated":"2023-03-08T15:08:46Z","content_type":"application/pdf","file_id":"12718","creator":"lburnett"}],"ddc":["599","573"],"page":"178","oa":1,"OA_place":"publisher","_id":"12716","file_date_updated":"2023-03-08T15:08:46Z","corr_author":"1","type":"dissertation","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","author":[{"orcid":"0000-0002-8937-410X","first_name":"Laura","id":"3B717F68-F248-11E8-B48F-1D18A9856A87","full_name":"Burnett, Laura","last_name":"Burnett"}],"day":"10","oa_version":"Published Version","ec_funded":1,"project":[{"name":"Circuits of Visual Attention","_id":"2634E9D2-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"756502"}],"alternative_title":["ISTA Thesis"],"abstract":[{"text":"The process of detecting and evaluating sensory information to guide behaviour is termed perceptual decision-making (PDM), and is critical for the ability of an organism to interact with its external world. Individuals with autism, a neurodevelopmental condition primarily characterised by social and communication difficulties, frequently exhibit altered sensory processing and PDM difficulties are widely reported. Recent technological advancements have pushed forward our understanding of the genetic changes accompanying this condition, however our understanding of how these mutations affect the function of specific neuronal circuits and bring about the corresponding behavioural changes remains limited. Here, we use an innate PDM task, the looming avoidance response (LAR) paradigm, to identify a convergent behavioural abnormality across three molecularly distinct genetic mouse models of autism (Cul3, Setd5 and Ptchd1). Although mutant mice can rapidly detect threatening visual stimuli, their responses are consistently delayed, requiring longer to initiate an appropriate response than their wild-type siblings. Mutant animals show abnormal adaptation in both their stimulus- evoked escape responses and exploratory dynamics following repeated stimulus presentations. Similarly delayed behavioural responses are observed in wild-type animals when faced with more ambiguous threats, suggesting the mutant phenotype could arise from a dysfunction in the flexible control of this PDM process.\r\nOur knowledge of the core neuronal circuitry mediating the LAR facilitated a detailed dissection of the neuronal mechanisms underlying the behavioural impairment. In vivo extracellular recording revealed that visual responses were unaffected within a key brain region for the rapid processing of visual threats, the superior colliculus (SC), indicating that the behavioural delay was unlikely to originate from sensory impairments. Delayed behavioural responses were recapitulated in the Setd5 model following optogenetic stimulation of the excitatory output neurons of the SC, which are known to mediate escape initiation through the activation of cells in the underlying dorsal periaqueductal grey (dPAG). In vitro patch-clamp recordings of dPAG cells uncovered a stark hypoexcitability phenotype in two out of the three genetic models investigated (Setd5 and Ptchd1), that in Setd5, is mediated by the misregulation of voltage-gated potassium channels. Overall, our results show that the ability to use visual information to drive efficient escape responses is impaired in three diverse genetic mouse models of autism and that, in one of the models studied, this behavioural delay likely originates from differences in the intrinsic excitability of a key subcortical node, the dPAG. Furthermore, this work showcases the use of an innate behavioural paradigm to mechanistically dissect PDM processes in autism.","lang":"eng"}],"citation":{"apa":"Burnett, L. (2023). <i>To flee, or not to flee? Using innate defensive behaviours to investigate rapid perceptual decision-making through subcortical circuits in mouse models of autism</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:12716\">https://doi.org/10.15479/at:ista:12716</a>","short":"L. Burnett, To Flee, or Not to Flee? Using Innate Defensive Behaviours to Investigate Rapid Perceptual Decision-Making through Subcortical Circuits in Mouse Models of Autism, Institute of Science and Technology Austria, 2023.","chicago":"Burnett, Laura. “To Flee, or Not to Flee? Using Innate Defensive Behaviours to Investigate Rapid Perceptual Decision-Making through Subcortical Circuits in Mouse Models of Autism.” Institute of Science and Technology Austria, 2023. <a href=\"https://doi.org/10.15479/at:ista:12716\">https://doi.org/10.15479/at:ista:12716</a>.","ama":"Burnett L. To flee, or not to flee? Using innate defensive behaviours to investigate rapid perceptual decision-making through subcortical circuits in mouse models of autism. 2023. doi:<a href=\"https://doi.org/10.15479/at:ista:12716\">10.15479/at:ista:12716</a>","ista":"Burnett L. 2023. To flee, or not to flee? Using innate defensive behaviours to investigate rapid perceptual decision-making through subcortical circuits in mouse models of autism. Institute of Science and Technology Austria.","mla":"Burnett, Laura. <i>To Flee, or Not to Flee? Using Innate Defensive Behaviours to Investigate Rapid Perceptual Decision-Making through Subcortical Circuits in Mouse Models of Autism</i>. Institute of Science and Technology Austria, 2023, doi:<a href=\"https://doi.org/10.15479/at:ista:12716\">10.15479/at:ista:12716</a>.","ieee":"L. Burnett, “To flee, or not to flee? Using innate defensive behaviours to investigate rapid perceptual decision-making through subcortical circuits in mouse models of autism,” Institute of Science and Technology Austria, 2023."},"date_published":"2023-03-10T00:00:00Z","year":"2023","degree_awarded":"PhD","publication_status":"published","doi":"10.15479/at:ista:12716","article_processing_charge":"No","publication_identifier":{"issn":["2663-337X"]},"publisher":"Institute of Science and Technology Austria","department":[{"_id":"GradSch"},{"_id":"MaJö"}],"month":"03","date_updated":"2026-04-07T13:25:15Z","title":"To flee, or not to flee? Using innate defensive behaviours to investigate rapid perceptual decision-making through subcortical circuits in mouse models of autism"},{"abstract":[{"lang":"eng","text":"Superconductor-semiconductor heterostructures currently capture a significant amount of research interest and they serve as the physical platform in many proposals towards topological quantum computation.\r\nDespite being under extensive investigations, historically using transport techniques, the basic properties of the interface between the superconductor and the semiconductor remain to be understood.\r\n\r\nIn this thesis, two separate studies on the Al-InAs heterostructures are reported with the first focusing on the physics of the material motivated by the emergence of a new phase, the Bogoliubov-Fermi surface. \r\nThe second focuses on a technological application, a gate-tunable Josephson parametric amplifier.\r\n\r\nIn the first study, we investigate the hypothesized unconventional nature of the induced superconductivity at the interface between the Al thin film and the InAs quantum well.\r\nWe embed a two-dimensional Al-InAs hybrid system in a resonant microwave circuit allowing measurements of change in inductance.\r\nThe behaviour of the resonance in a range of temperature and in-plane magnetic field has been studied and compared with the theory of conventional s-wave superconductor and a two-component theory that includes both contribution of the $s$-wave pairing in Al and the intraband $p \\pm ip$ pairing in InAs.\r\nMeasuring the temperature dependence of resonant frequency, no discrepancy is found between data and the conventional theory.\r\nWe observe the breakdown of superconductivity due to an applied magnetic field which contradicts the conventional theory.\r\nIn contrast, the data can be captured quantitatively by fitting to a two-component model.\r\nWe find the evidence of the intraband $p \\pm ip$ pairing in the InAs and the emergence of the Bogoliubov-Fermi surfaces due to magnetic field with the characteristic value $B^* = 0.33~\\mathrm{T}$.\r\nFrom the fits, the sheet resistance of Al, the carrier density and mobility in InAs are determined.\r\nBy systematically studying the anisotropy of the circuit response, we find weak anisotropy for $B < B^*$ and increasingly strong anisotropy for $B > B^*$ resulting in a pronounced two-lobe structure in polar plot of frequency versus field angle.\r\nStrong resemblance between the field dependence of dissipation and superfluid density hints at a hidden signature of the Bogoliubov-Fermi surface that is burried in the dissipation data.\r\n\r\nIn the second study, we realize a parametric amplifier with a Josephson field effect transistor as the active element.\r\nThe device's modest construction consists of a gated SNS weak link embedded at the center of a coplanar waveguide resonator.\r\nBy applying a gate voltage, the resonant frequency is field-effect tunable over a range of 2 GHz.\r\nModelling the JoFET minimally as a parallel RL circuit, the dissipation introduced by the JoFET can be quantitatively related to the gate voltage.\r\nWe observed gate-tunable Kerr nonlinearity qualitatively in line with expectation.\r\nThe JoFET amplifier has 20 dB of gain, 4 MHz of instantaneous bandwidth, and a 1dB compression point of -125.5 dBm when operated at a fixed resonant frequency.\r\nIn general, the signal-to-noise ratio is improved by 5-7 dB when the JoFET amplifier is activated compared.\r\nThe noise of the measurement chain and insertion loss of relevant circuit elements are calibrated to determine the expected and the real noise performance of the JoFET amplifier.\r\nAs a quantification of the noise performance, the measured total input-referred noise of the JoFET amplifier is in good agreement with the estimated expectation which takes device loss into account.\r\nWe found that the noise performance of the device reported in this document approaches one photon of total input-referred added noise which is the quantum limit imposed in nondegenerate parametric amplifier."}],"alternative_title":["ISTA Thesis"],"oa_version":"Published Version","day":"16","title":"Resonant microwave spectroscopy of Al-InAs","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","image":"/images/cc_by_nc_sa.png","name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)","short":"CC BY-NC-SA (4.0)"},"date_updated":"2026-04-07T13:25:52Z","month":"11","department":[{"_id":"GradSch"},{"_id":"AnHi"}],"publication_status":"published","degree_awarded":"PhD","article_processing_charge":"No","publisher":"Institute of Science and Technology Austria","publication_identifier":{"issn":["2663-337X"]},"doi":"10.15479/14547","year":"2023","date_published":"2023-11-16T00:00:00Z","citation":{"chicago":"Phan, Duc T. “Resonant Microwave Spectroscopy of Al-InAs.” Institute of Science and Technology Austria, 2023. <a href=\"https://doi.org/10.15479/14547\">https://doi.org/10.15479/14547</a>.","ama":"Phan DT. Resonant microwave spectroscopy of Al-InAs. 2023. doi:<a href=\"https://doi.org/10.15479/14547\">10.15479/14547</a>","apa":"Phan, D. T. (2023). <i>Resonant microwave spectroscopy of Al-InAs</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/14547\">https://doi.org/10.15479/14547</a>","short":"D.T. Phan, Resonant Microwave Spectroscopy of Al-InAs, Institute of Science and Technology Austria, 2023.","mla":"Phan, Duc T. <i>Resonant Microwave Spectroscopy of Al-InAs</i>. Institute of Science and Technology Austria, 2023, doi:<a href=\"https://doi.org/10.15479/14547\">10.15479/14547</a>.","ieee":"D. T. Phan, “Resonant microwave spectroscopy of Al-InAs,” Institute of Science and Technology Austria, 2023.","ista":"Phan DT. 2023. Resonant microwave spectroscopy of Al-InAs. Institute of Science and Technology Austria."},"page":"80","file":[{"date_updated":"2023-11-22T09:46:06Z","file_name":"Phan_Thesis_pdfa.pdf","content_type":"application/pdf","file_id":"14548","creator":"pduc","date_created":"2023-11-17T13:36:44Z","checksum":"db0c37d213bc002125bd59690e9db246","access_level":"open_access","relation":"main_file","file_size":34828019},{"access_level":"closed","relation":"source_file","file_size":279319709,"date_created":"2023-11-17T13:44:53Z","checksum":"8d3bd6afa279a0078ffd13e06bb6d56d","file_id":"14549","creator":"pduc","file_name":"dissertation_src.zip","date_updated":"2023-11-17T13:47:54Z","content_type":"application/zip"}],"ddc":["530"],"has_accepted_license":"1","acknowledged_ssus":[{"_id":"NanoFab"},{"_id":"Bio"}],"language":[{"iso":"eng"}],"supervisor":[{"orcid":"0000-0003-2607-2363","first_name":"Andrew P","id":"4AD6785A-F248-11E8-B48F-1D18A9856A87","full_name":"Higginbotham, Andrew P","last_name":"Higginbotham"}],"status":"public","date_created":"2023-11-17T13:45:26Z","keyword":["superconductor-semiconductor","superconductivity","Al","InAs","p-wave","superconductivity","JPA","microwave"],"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","author":[{"id":"29C8C0B4-F248-11E8-B48F-1D18A9856A87","full_name":"Phan, Duc T","last_name":"Phan","first_name":"Duc T"}],"type":"dissertation","file_date_updated":"2023-11-22T09:46:06Z","corr_author":"1","_id":"14547","OA_place":"publisher","oa":1,"related_material":{"record":[{"relation":"part_of_dissertation","status":"public","id":"13264"},{"id":"10851","status":"public","relation":"part_of_dissertation"}]}},{"oa":1,"related_material":{"record":[{"id":"9803","status":"public","relation":"research_data"},{"relation":"research_data","status":"public","id":"12933"},{"relation":"part_of_dissertation","id":"6831","status":"public"},{"status":"public","id":"14077","relation":"part_of_dissertation"}]},"OA_place":"publisher","_id":"14058","corr_author":"1","file_date_updated":"2023-08-18T10:47:55Z","type":"dissertation","author":[{"first_name":"Gemma","orcid":"0000-0001-8330-1754","full_name":"Puixeu Sala, Gemma","id":"33AB266C-F248-11E8-B48F-1D18A9856A87","last_name":"Puixeu Sala"}],"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","date_created":"2023-08-15T10:20:40Z","status":"public","supervisor":[{"id":"49E1C5C6-F248-11E8-B48F-1D18A9856A87","full_name":"Vicoso, Beatriz","last_name":"Vicoso","orcid":"0000-0002-4579-8306","first_name":"Beatriz"},{"id":"4880FE40-F248-11E8-B48F-1D18A9856A87","full_name":"Barton, Nicholas H","last_name":"Barton","orcid":"0000-0002-8548-5240","first_name":"Nicholas H"}],"language":[{"iso":"eng"}],"has_accepted_license":"1","ddc":["576"],"file":[{"relation":"source_file","file_size":10891454,"access_level":"closed","checksum":"4e44e169f2724ee8c9324cd60bcc2b71","date_created":"2023-08-16T18:15:17Z","file_id":"14075","creator":"gpuixeus","content_type":"application/zip","file_name":"Thesis_latex_forpdfa.zip","date_updated":"2023-08-17T06:55:24Z"},{"access_level":"open_access","success":1,"file_size":19856686,"relation":"main_file","date_created":"2023-08-18T10:47:55Z","checksum":"e10b04cd8f3fecc0d9ef6e6868b6e1e8","file_id":"14079","creator":"gpuixeus","date_updated":"2023-08-18T10:47:55Z","file_name":"PhDThesis_PuixeuG.pdf","content_type":"application/pdf"}],"page":"230","citation":{"ieee":"G. Puixeu Sala, “The molecular basis of sexual dimorphism: Experimental and theoretical characterization of phenotypic, transcriptomic and genetic patterns of sex-specific adaptation,” Institute of Science and Technology Austria, 2023.","mla":"Puixeu Sala, Gemma. <i>The Molecular Basis of Sexual Dimorphism: Experimental and Theoretical Characterization of Phenotypic, Transcriptomic and Genetic Patterns of Sex-Specific Adaptation</i>. Institute of Science and Technology Austria, 2023, doi:<a href=\"https://doi.org/10.15479/at:ista:14058\">10.15479/at:ista:14058</a>.","ista":"Puixeu Sala G. 2023. The molecular basis of sexual dimorphism: Experimental and theoretical characterization of phenotypic, transcriptomic and genetic patterns of sex-specific adaptation. Institute of Science and Technology Austria.","ama":"Puixeu Sala G. The molecular basis of sexual dimorphism: Experimental and theoretical characterization of phenotypic, transcriptomic and genetic patterns of sex-specific adaptation. 2023. doi:<a href=\"https://doi.org/10.15479/at:ista:14058\">10.15479/at:ista:14058</a>","chicago":"Puixeu Sala, Gemma. “The Molecular Basis of Sexual Dimorphism: Experimental and Theoretical Characterization of Phenotypic, Transcriptomic and Genetic Patterns of Sex-Specific Adaptation.” Institute of Science and Technology Austria, 2023. <a href=\"https://doi.org/10.15479/at:ista:14058\">https://doi.org/10.15479/at:ista:14058</a>.","short":"G. Puixeu Sala, The Molecular Basis of Sexual Dimorphism: Experimental and Theoretical Characterization of Phenotypic, Transcriptomic and Genetic Patterns of Sex-Specific Adaptation, Institute of Science and Technology Austria, 2023.","apa":"Puixeu Sala, G. (2023). <i>The molecular basis of sexual dimorphism: Experimental and theoretical characterization of phenotypic, transcriptomic and genetic patterns of sex-specific adaptation</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:14058\">https://doi.org/10.15479/at:ista:14058</a>"},"date_published":"2023-08-15T00:00:00Z","year":"2023","doi":"10.15479/at:ista:14058","article_processing_charge":"No","publisher":"Institute of Science and Technology Austria","publication_identifier":{"isbn":["978-3-99078-035-0"],"issn":["2663-337X"]},"publication_status":"published","degree_awarded":"PhD","department":[{"_id":"GradSch"},{"_id":"NiBa"},{"_id":"BeVi"}],"month":"08","date_updated":"2026-04-07T13:25:34Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"title":"The molecular basis of sexual dimorphism: Experimental and theoretical characterization of phenotypic, transcriptomic and genetic patterns of sex-specific adaptation","ec_funded":1,"oa_version":"Published Version","day":"15","alternative_title":["ISTA Thesis"],"project":[{"grant_number":"665385","call_identifier":"H2020","name":"International IST Doctoral Program","_id":"2564DBCA-B435-11E9-9278-68D0E5697425"},{"name":"Sexual conflict: resolution, constraints and biomedical implications","_id":"9B9DFC9E-BA93-11EA-9121-9846C619BF3A","grant_number":"25817"}],"abstract":[{"text":"Females and males across species are subject to divergent selective pressures arising\r\nfrom di↵erent reproductive interests and ecological niches. This often translates into a\r\nintricate array of sex-specific natural and sexual selection on traits that have a shared\r\ngenetic basis between both sexes, causing a genetic sexual conflict. The resolution of\r\nthis conflict mostly relies on the evolution of sex-specific expression of the shared genes,\r\nleading to phenotypic sexual dimorphism. Such sex-specific gene expression is thought\r\nto evolve via modifications of the genetic networks ultimately linked to sex-determining\r\ntranscription factors. Although much empirical and theoretical evidence supports this\r\nstandard picture of the molecular basis of sexual conflict resolution, there still are a\r\nfew open questions regarding the complex array of selective forces driving phenotypic\r\ndi↵erentiation between the sexes, as well as the molecular mechanisms underlying sexspecific adaptation. I address some of these open questions in my PhD thesis.\r\nFirst, how do patterns of phenotypic sexual dimorphism vary within populations,\r\nas a response to the temporal and spatial changes in sex-specific selective forces? To\r\ntackle this question, I analyze the patterns of sex-specific phenotypic variation along\r\nthree life stages and across populations spanning the whole geographical range of Rumex\r\nhastatulus, a wind-pollinated angiosperm, in the first Chapter of the thesis.\r\nSecond, how do gene expression patterns lead to phenotypic dimorphism, and what\r\nare the molecular mechanisms underlying the observed transcriptomic variation? I\r\naddress this question by examining the sex- and tissue-specific expression variation in\r\nnewly-generated datasets of sex-specific expression in heads and gonads of Drosophila\r\nmelanogaster. I additionally used two complementary approaches for the study of the\r\ngenetic basis of sex di↵erences in gene expression in the second and third Chapters of\r\nthe thesis.\r\nThird, how does intersex correlation, thought to be one of the main aspects constraining the ability for the two sexes to decouple, interact with the evolution of sexual\r\ndimorphism? I develop models of sex-specific stabilizing selection, mutation and drift\r\nto formalize common intuition regarding the patterns of covariation between intersex\r\ncorrelation and sexual dimorphism in the fourth Chapter of the thesis.\r\nAlltogether, the work described in this PhD thesis provides useful insights into the\r\nlinks between genetic, transcriptomic and phenotypic layers of sex-specific variation,\r\nand contributes to our general understanding of the dynamics of sexual dimorphism\r\nevolution.","lang":"eng"}]},{"keyword":["Genetics (clinical)","Genetics","Molecular Biology"],"date_created":"2023-08-18T06:52:14Z","scopus_import":"1","status":"public","language":[{"iso":"eng"}],"publication":"G3: Genes, Genomes, Genetics","has_accepted_license":"1","acknowledged_ssus":[{"_id":"ScienComp"}],"ddc":["570"],"file":[{"date_updated":"2023-11-07T09:00:19Z","file_name":"2023_G3_Puixeu.pdf","content_type":"application/pdf","file_id":"14498","creator":"dernst","date_created":"2023-11-07T09:00:19Z","checksum":"c62e29fc7c5efbf8356f4c60cab4a2d1","success":1,"access_level":"open_access","file_size":845642,"relation":"main_file"}],"intvolume":"        13","pmid":1,"oa":1,"related_material":{"record":[{"relation":"research_data","status":"public","id":"12933"},{"relation":"dissertation_contains","id":"14058","status":"public"}]},"_id":"14077","issue":"8","corr_author":"1","file_date_updated":"2023-11-07T09:00:19Z","type":"journal_article","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"first_name":"Gemma","orcid":"0000-0001-8330-1754","last_name":"Puixeu Sala","full_name":"Puixeu Sala, Gemma","id":"33AB266C-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Macon, Ariana","id":"2A0848E2-F248-11E8-B48F-1D18A9856A87","last_name":"Macon","first_name":"Ariana"},{"orcid":"0000-0002-4579-8306","first_name":"Beatriz","last_name":"Vicoso","id":"49E1C5C6-F248-11E8-B48F-1D18A9856A87","full_name":"Vicoso, Beatriz"}],"acknowledgement":"We thank members of the Vicoso Group for comments on the manuscript, the Scientific Computing Unit at ISTA for technical support, and 2 anonymous reviewers for useful feedback. GP is the recipient of a DOC Fellowship of the Austrian Academy of Sciences at the Institute of Science and Technology Austria (DOC 25817) and received funding from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie Grant (agreement no. 665385).","ec_funded":1,"oa_version":"Published Version","volume":13,"day":"01","project":[{"name":"International IST Doctoral Program","_id":"2564DBCA-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"665385"},{"name":"Sexual conflict: resolution, constraints and biomedical implications","_id":"9B9DFC9E-BA93-11EA-9121-9846C619BF3A","grant_number":"25817"}],"quality_controlled":"1","external_id":{"pmid":["37259621"],"isi":["001002997200001"]},"article_type":"original","abstract":[{"lang":"eng","text":"The regulatory architecture of gene expression is known to differ substantially between sexes in Drosophila, but most studies performed\r\nso far used whole-body data and only single crosses, which may have limited their scope to detect patterns that are robust across tissues\r\nand biological replicates. Here, we use allele-specific gene expression of parental and reciprocal hybrid crosses between 6 Drosophila\r\nmelanogaster inbred lines to quantify cis- and trans-regulatory variation in heads and gonads of both sexes separately across 3 replicate\r\ncrosses. Our results suggest that female and male heads, as well as ovaries, have a similar regulatory architecture. On the other hand,\r\ntestes display more and substantially different cis-regulatory effects, suggesting that sex differences in the regulatory architecture that\r\nhave been previously observed may largely derive from testis-specific effects. We also examine the difference in cis-regulatory variation\r\nof genes across different levels of sex bias in gonads and heads. Consistent with the idea that intersex correlations constrain expression\r\nand can lead to sexual antagonism, we find more cis variation in unbiased and moderately biased genes in heads. In ovaries, reduced cis\r\nvariation is observed for male-biased genes, suggesting that cis variants acting on these genes in males do not lead to changes in ovary\r\nexpression. Finally, we examine the dominance patterns of gene expression and find that sex- and tissue-specific patterns of inheritance\r\nas well as trans-regulatory variation are highly variable across biological crosses, although these were performed in highly controlled\r\nexperimental conditions. This highlights the importance of using various genetic backgrounds to infer generalizable patterns."}],"citation":{"apa":"Puixeu Sala, G., Macon, A., &#38; Vicoso, B. (2023). Sex-specific estimation of cis and trans regulation of gene expression in heads and gonads of Drosophila melanogaster. <i>G3: Genes, Genomes, Genetics</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/g3journal/jkad121\">https://doi.org/10.1093/g3journal/jkad121</a>","short":"G. Puixeu Sala, A. Macon, B. Vicoso, G3: Genes, Genomes, Genetics 13 (2023).","chicago":"Puixeu Sala, Gemma, Ariana Macon, and Beatriz Vicoso. “Sex-Specific Estimation of Cis and Trans Regulation of Gene Expression in Heads and Gonads of Drosophila Melanogaster.” <i>G3: Genes, Genomes, Genetics</i>. Oxford University Press, 2023. <a href=\"https://doi.org/10.1093/g3journal/jkad121\">https://doi.org/10.1093/g3journal/jkad121</a>.","ama":"Puixeu Sala G, Macon A, Vicoso B. Sex-specific estimation of cis and trans regulation of gene expression in heads and gonads of Drosophila melanogaster. <i>G3: Genes, Genomes, Genetics</i>. 2023;13(8). doi:<a href=\"https://doi.org/10.1093/g3journal/jkad121\">10.1093/g3journal/jkad121</a>","ista":"Puixeu Sala G, Macon A, Vicoso B. 2023. Sex-specific estimation of cis and trans regulation of gene expression in heads and gonads of Drosophila melanogaster. G3: Genes, Genomes, Genetics. 13(8).","mla":"Puixeu Sala, Gemma, et al. “Sex-Specific Estimation of Cis and Trans Regulation of Gene Expression in Heads and Gonads of Drosophila Melanogaster.” <i>G3: Genes, Genomes, Genetics</i>, vol. 13, no. 8, Oxford University Press, 2023, doi:<a href=\"https://doi.org/10.1093/g3journal/jkad121\">10.1093/g3journal/jkad121</a>.","ieee":"G. Puixeu Sala, A. Macon, and B. Vicoso, “Sex-specific estimation of cis and trans regulation of gene expression in heads and gonads of Drosophila melanogaster,” <i>G3: Genes, Genomes, Genetics</i>, vol. 13, no. 8. Oxford University Press, 2023."},"date_published":"2023-08-01T00:00:00Z","year":"2023","doi":"10.1093/g3journal/jkad121","article_processing_charge":"Yes","publication_identifier":{"issn":["2160-1836"]},"publisher":"Oxford University Press","publication_status":"published","month":"08","department":[{"_id":"BeVi"},{"_id":"NiBa"},{"_id":"GradSch"}],"date_updated":"2026-04-07T13:25:34Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"isi":1,"title":"Sex-specific estimation of cis and trans regulation of gene expression in heads and gonads of Drosophila melanogaster"},{"intvolume":"        19","publication":"Physical Review Applied","language":[{"iso":"eng"}],"acknowledged_ssus":[{"_id":"NanoFab"},{"_id":"M-Shop"}],"status":"public","scopus_import":"1","date_created":"2023-07-23T22:01:12Z","author":[{"id":"29C8C0B4-F248-11E8-B48F-1D18A9856A87","full_name":"Phan, Duc T","last_name":"Phan","first_name":"Duc T"},{"first_name":"Paul","last_name":"Falthansl-Scheinecker","full_name":"Falthansl-Scheinecker, Paul","id":"85b43b21-15b2-11ec-abd3-e2c252cc2285"},{"last_name":"Mishra","id":"4328fa4c-f128-11eb-9611-c107b0fe4d51","full_name":"Mishra, Umang","first_name":"Umang"},{"first_name":"W. M.","full_name":"Strickland, W. M.","last_name":"Strickland"},{"first_name":"D.","full_name":"Langone, D.","last_name":"Langone"},{"first_name":"J.","full_name":"Shabani, J.","last_name":"Shabani"},{"last_name":"Higginbotham","id":"4AD6785A-F248-11E8-B48F-1D18A9856A87","full_name":"Higginbotham, Andrew P","first_name":"Andrew P","orcid":"0000-0003-2607-2363"}],"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","acknowledgement":"We thank Shyam Shankar for helpful feedback on the manuscript. We gratefully acknowledge the support of the ISTA nanofabrication facility, the Miba Machine Shop, and the eMachine Shop. The NYU team acknowledges support from Army Research Office Grant No. W911NF2110303.","type":"journal_article","corr_author":"1","issue":"6","arxiv":1,"_id":"13264","related_material":{"record":[{"id":"14547","status":"public","relation":"dissertation_contains"}]},"oa":1,"article_type":"original","main_file_link":[{"url":"https://arxiv.org/abs/2206.05746","open_access":"1"}],"abstract":[{"lang":"eng","text":"We build a parametric amplifier with a Josephson field-effect transistor (JoFET) as the active element. The resonant frequency of the device is field-effect tunable over a range of 2 GHz. The JoFET amplifier has 20 dB of gain, 4 MHz of instantaneous bandwidth, and a 1-dB compression point of -125.5 dBm when operated at a fixed resonance frequency.\r\n\r\n"}],"external_id":{"isi":["001012022600004"],"arxiv":["2206.05746"]},"quality_controlled":"1","oa_version":"Preprint","day":"09","volume":19,"article_number":"064032","isi":1,"title":"Gate-tunable superconductor-semiconductor parametric amplifier","date_updated":"2026-04-07T13:25:51Z","month":"06","department":[{"_id":"AnHi"},{"_id":"OnHo"}],"publication_identifier":{"eissn":["2331-7019"]},"publisher":"American Physical Society","article_processing_charge":"No","doi":"10.1103/PhysRevApplied.19.064032","publication_status":"published","year":"2023","date_published":"2023-06-09T00:00:00Z","citation":{"apa":"Phan, D. T., Falthansl-Scheinecker, P., Mishra, U., Strickland, W. M., Langone, D., Shabani, J., &#38; Higginbotham, A. P. (2023). Gate-tunable superconductor-semiconductor parametric amplifier. <i>Physical Review Applied</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevApplied.19.064032\">https://doi.org/10.1103/PhysRevApplied.19.064032</a>","short":"D.T. Phan, P. Falthansl-Scheinecker, U. Mishra, W.M. Strickland, D. Langone, J. Shabani, A.P. Higginbotham, Physical Review Applied 19 (2023).","chicago":"Phan, Duc T, Paul Falthansl-Scheinecker, Umang Mishra, W. M. Strickland, D. Langone, J. Shabani, and Andrew P Higginbotham. “Gate-Tunable Superconductor-Semiconductor Parametric Amplifier.” <i>Physical Review Applied</i>. American Physical Society, 2023. <a href=\"https://doi.org/10.1103/PhysRevApplied.19.064032\">https://doi.org/10.1103/PhysRevApplied.19.064032</a>.","ama":"Phan DT, Falthansl-Scheinecker P, Mishra U, et al. Gate-tunable superconductor-semiconductor parametric amplifier. <i>Physical Review Applied</i>. 2023;19(6). doi:<a href=\"https://doi.org/10.1103/PhysRevApplied.19.064032\">10.1103/PhysRevApplied.19.064032</a>","ista":"Phan DT, Falthansl-Scheinecker P, Mishra U, Strickland WM, Langone D, Shabani J, Higginbotham AP. 2023. Gate-tunable superconductor-semiconductor parametric amplifier. Physical Review Applied. 19(6), 064032.","mla":"Phan, Duc T., et al. “Gate-Tunable Superconductor-Semiconductor Parametric Amplifier.” <i>Physical Review Applied</i>, vol. 19, no. 6, 064032, American Physical Society, 2023, doi:<a href=\"https://doi.org/10.1103/PhysRevApplied.19.064032\">10.1103/PhysRevApplied.19.064032</a>.","ieee":"D. T. Phan <i>et al.</i>, “Gate-tunable superconductor-semiconductor parametric amplifier,” <i>Physical Review Applied</i>, vol. 19, no. 6. American Physical Society, 2023."}},{"has_accepted_license":"1","status":"public","date_created":"2023-05-10T10:00:49Z","day":"15","oa_version":"Published Version","ddc":["570"],"abstract":[{"lang":"eng","text":"Datasets of the publication \"Sex-specific estimation of cis and trans regulation of gene expression in heads and gonads of Drosophila melanogaster\"."}],"file":[{"date_created":"2023-05-10T09:41:43Z","checksum":"0ba0bcd0bb8b18d84792136a4370df90","success":1,"access_level":"open_access","file_size":8029982,"relation":"main_file","date_updated":"2023-05-10T09:41:43Z","file_name":"Dataset_S1.csv","content_type":"text/csv","creator":"gpuixeus","file_id":"12934"},{"file_name":"Dataset_S2.csv","date_updated":"2023-05-10T09:41:43Z","content_type":"text/csv","creator":"gpuixeus","file_id":"12935","date_created":"2023-05-10T09:41:43Z","checksum":"a62aa9a6d4904e0fdb699cf752640863","success":1,"access_level":"open_access","relation":"main_file","file_size":13667640},{"access_level":"open_access","success":1,"file_size":8369141,"relation":"main_file","date_created":"2023-05-10T09:41:48Z","checksum":"e20ea7f4f8a9bdf1b3849a44664ae58b","creator":"gpuixeus","file_id":"12936","file_name":"Dataset_S3.csv","date_updated":"2023-05-10T09:41:48Z","content_type":"text/csv"},{"success":1,"access_level":"open_access","relation":"main_file","file_size":19543247,"date_created":"2023-05-10T09:41:50Z","checksum":"f6156e5fc44446c907ddd0d7289d4cf8","creator":"gpuixeus","file_id":"12937","date_updated":"2023-05-10T09:41:50Z","file_name":"Dataset_S4.csv","content_type":"text/csv"},{"relation":"main_file","file_size":4566,"access_level":"open_access","success":1,"checksum":"ae9f54c77a1c42b666ae6c1dfd33ac86","date_created":"2023-05-11T12:50:18Z","creator":"gpuixeus","file_id":"12944","content_type":"text/plain","file_name":"readme.txt","date_updated":"2023-05-11T12:50:18Z"}],"doi":"10.15479/AT:ISTA:12933","article_processing_charge":"No","publisher":"Institute of Science and Technology Austria","_id":"12933","citation":{"short":"G. Puixeu Sala, (2023).","apa":"Puixeu Sala, G. (2023). Data from: Sex-specific estimation of cis and trans regulation of gene expression in heads and gonads of Drosophila melanogaster. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:12933\">https://doi.org/10.15479/AT:ISTA:12933</a>","ama":"Puixeu Sala G. Data from: Sex-specific estimation of cis and trans regulation of gene expression in heads and gonads of Drosophila melanogaster. 2023. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:12933\">10.15479/AT:ISTA:12933</a>","chicago":"Puixeu Sala, Gemma. “Data from: Sex-Specific Estimation of Cis and Trans Regulation of Gene Expression in Heads and Gonads of Drosophila Melanogaster.” Institute of Science and Technology Austria, 2023. <a href=\"https://doi.org/10.15479/AT:ISTA:12933\">https://doi.org/10.15479/AT:ISTA:12933</a>.","ista":"Puixeu Sala G. 2023. Data from: Sex-specific estimation of cis and trans regulation of gene expression in heads and gonads of Drosophila melanogaster, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:12933\">10.15479/AT:ISTA:12933</a>.","ieee":"G. Puixeu Sala, “Data from: Sex-specific estimation of cis and trans regulation of gene expression in heads and gonads of Drosophila melanogaster.” Institute of Science and Technology Austria, 2023.","mla":"Puixeu Sala, Gemma. <i>Data from: Sex-Specific Estimation of Cis and Trans Regulation of Gene Expression in Heads and Gonads of Drosophila Melanogaster</i>. Institute of Science and Technology Austria, 2023, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:12933\">10.15479/AT:ISTA:12933</a>."},"related_material":{"record":[{"relation":"used_in_publication","status":"public","id":"14077"},{"relation":"used_in_publication","id":"14058","status":"public"}]},"date_published":"2023-05-15T00:00:00Z","year":"2023","oa":1,"type":"research_data","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"last_name":"Puixeu Sala","full_name":"Puixeu Sala, Gemma","id":"33AB266C-F248-11E8-B48F-1D18A9856A87","first_name":"Gemma","orcid":"0000-0001-8330-1754"}],"title":"Data from: Sex-specific estimation of cis and trans regulation of gene expression in heads and gonads of Drosophila melanogaster","contributor":[{"last_name":"Macon","id":"2A0848E2-F248-11E8-B48F-1D18A9856A87","first_name":"Ariana"},{"id":"49E1C5C6-F248-11E8-B48F-1D18A9856A87","last_name":"Vicoso","orcid":"0000-0002-4579-8306","first_name":"Beatriz"}],"department":[{"_id":"GradSch"},{"_id":"NiBa"},{"_id":"BeVi"}],"month":"05","date_updated":"2026-04-07T13:25:33Z","corr_author":"1","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"file_date_updated":"2023-05-11T12:50:18Z"},{"day":"28","oa_version":"Published Version","ec_funded":1,"project":[{"name":"International IST Doctoral Program","_id":"2564DBCA-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"665385"}],"alternative_title":["ISTA Thesis"],"abstract":[{"lang":"eng","text":"High-performance semiconductors rely upon precise control of heat and charge transport. This can be achieved by precisely engineering defects in polycrystalline solids. There are multiple approaches to preparing such polycrystalline semiconductors, and the transformation of solution-processed colloidal nanoparticles is appealing because colloidal nanoparticles combine low cost with structural and compositional tunability along with rich surface chemistry. However, the multiple processes from nanoparticle synthesis to the final bulk nanocomposites are very complex. They involve nanoparticle purification, post-synthetic modifications, and finally consolidation (thermal treatments and densification). All these properties dictate the final material’s composition and microstructure, ultimately affecting its functional properties. This thesis explores the synthesis, surface chemistry and consolidation of colloidal semiconductor nanoparticles into dense solids. In particular, the transformations that take place during these processes, and their effect on the material’s transport properties are evaluated. "}],"date_published":"2023-04-28T00:00:00Z","year":"2023","citation":{"ista":"Calcabrini M. 2023. Nanoparticle-based semiconductor solids: From synthesis to consolidation. Institute of Science and Technology Austria.","ieee":"M. Calcabrini, “Nanoparticle-based semiconductor solids: From synthesis to consolidation,” Institute of Science and Technology Austria, 2023.","mla":"Calcabrini, Mariano. <i>Nanoparticle-Based Semiconductor Solids: From Synthesis to Consolidation</i>. Institute of Science and Technology Austria, 2023, doi:<a href=\"https://doi.org/10.15479/at:ista:12885\">10.15479/at:ista:12885</a>.","short":"M. Calcabrini, Nanoparticle-Based Semiconductor Solids: From Synthesis to Consolidation, Institute of Science and Technology Austria, 2023.","apa":"Calcabrini, M. (2023). <i>Nanoparticle-based semiconductor solids: From synthesis to consolidation</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:12885\">https://doi.org/10.15479/at:ista:12885</a>","ama":"Calcabrini M. Nanoparticle-based semiconductor solids: From synthesis to consolidation. 2023. doi:<a href=\"https://doi.org/10.15479/at:ista:12885\">10.15479/at:ista:12885</a>","chicago":"Calcabrini, Mariano. “Nanoparticle-Based Semiconductor Solids: From Synthesis to Consolidation.” Institute of Science and Technology Austria, 2023. <a href=\"https://doi.org/10.15479/at:ista:12885\">https://doi.org/10.15479/at:ista:12885</a>."},"degree_awarded":"PhD","publication_status":"published","publisher":"Institute of Science and Technology Austria","article_processing_charge":"No","publication_identifier":{"issn":["2663-337X"],"isbn":["978-3-99078-028-2"]},"doi":"10.15479/at:ista:12885","date_updated":"2026-04-07T13:26:14Z","month":"04","department":[{"_id":"GradSch"},{"_id":"MaIb"}],"title":"Nanoparticle-based semiconductor solids: From synthesis to consolidation","supervisor":[{"full_name":"Ibáñez, Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87","last_name":"Ibáñez","orcid":"0000-0001-5013-2843","first_name":"Maria"}],"status":"public","date_created":"2023-05-02T07:58:57Z","has_accepted_license":"1","acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"NanoFab"}],"language":[{"iso":"eng"}],"file":[{"checksum":"9347b0e09425f56fdcede5d3528404dc","date_created":"2023-05-02T07:43:18Z","file_size":99627036,"relation":"source_file","access_level":"closed","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","date_updated":"2023-05-02T07:43:18Z","file_name":"Thesis_Calcabrini.docx","file_id":"12887","creator":"mcalcabr"},{"access_level":"open_access","success":1,"file_size":8742220,"relation":"main_file","date_created":"2023-05-02T07:42:45Z","checksum":"2d188b76621086cd384f0b9264b0a576","creator":"mcalcabr","file_id":"12888","date_updated":"2023-05-02T07:42:45Z","file_name":"Thesis_Calcabrini_pdfa.pdf","content_type":"application/pdf"}],"ddc":["546","541"],"page":"82","related_material":{"record":[{"relation":"part_of_dissertation","id":"12237","status":"public"},{"id":"10806","status":"public","relation":"part_of_dissertation"},{"relation":"part_of_dissertation","status":"public","id":"10123"},{"relation":"part_of_dissertation","id":"10042","status":"public"},{"relation":"part_of_dissertation","id":"9118","status":"public"}]},"oa":1,"_id":"12885","OA_place":"publisher","file_date_updated":"2023-05-02T07:43:18Z","corr_author":"1","author":[{"orcid":"0000-0003-4566-5877","first_name":"Mariano","id":"45D7531A-F248-11E8-B48F-1D18A9856A87","full_name":"Calcabrini, Mariano","last_name":"Calcabrini"}],"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","type":"dissertation"},{"file":[{"creator":"pbrighi","file_id":"12753","file_name":"Thesis_sub_PBrighi.zip","date_updated":"2023-03-23T16:42:56Z","content_type":"application/zip","access_level":"closed","relation":"source_file","file_size":42167561,"date_created":"2023-03-23T16:42:56Z","checksum":"5d2de651ef9449c1b8dc27148ca74777"},{"file_name":"Thesis_PBrighi.pdf","date_updated":"2023-03-23T16:43:14Z","content_type":"application/pdf","creator":"pbrighi","file_id":"12754","date_created":"2023-03-23T16:43:14Z","checksum":"7caa153d4a5b0873a79358787d2dfe1e","success":1,"access_level":"open_access","relation":"main_file","file_size":13977000}],"ddc":["530"],"page":"158","supervisor":[{"id":"47809E7E-F248-11E8-B48F-1D18A9856A87","full_name":"Serbyn, Maksym","last_name":"Serbyn","first_name":"Maksym","orcid":"0000-0002-2399-5827"}],"date_created":"2023-03-17T13:30:48Z","status":"public","has_accepted_license":"1","acknowledged_ssus":[{"_id":"ScienComp"}],"language":[{"iso":"eng"}],"file_date_updated":"2023-03-23T16:43:14Z","corr_author":"1","type":"dissertation","author":[{"orcid":"0000-0002-7969-2729","first_name":"Pietro","last_name":"Brighi","id":"4115AF5C-F248-11E8-B48F-1D18A9856A87","full_name":"Brighi, Pietro"}],"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","related_material":{"record":[{"id":"12750","status":"public","relation":"part_of_dissertation"},{"status":"public","id":"11470","relation":"part_of_dissertation"},{"id":"8308","status":"public","relation":"part_of_dissertation"},{"relation":"part_of_dissertation","status":"public","id":"11469"}]},"oa":1,"OA_place":"publisher","_id":"12732","abstract":[{"lang":"eng","text":"Nonergodic systems, whose out-of-equilibrium dynamics fail to thermalize, provide a fascinating research direction both for fundamental reasons and for application in state of the art quantum devices.\r\nGoing beyond the description of statistical mechanics, ergodicity breaking yields a new paradigm in quantum many-body physics, introducing novel phases of matter with no counterpart at equilibrium.\r\nIn this Thesis, we address different open questions in the field, focusing on disorder-induced many-body localization (MBL) and on weak ergodicity breaking in kinetically constrained models.\r\nIn particular, we contribute to the debate about transport in kinetically constrained models, studying the effect of $U(1)$ conservation and inversion-symmetry breaking in a family of quantum East models.\r\nUsing tensor network techniques, we analyze the dynamics of large MBL systems beyond the limit of exact numerical methods.\r\nIn this setting, we approach the debated topic of the coexistence of localized and thermal eigenstates separated by energy thresholds known as many-body mobility edges.\r\nInspired by recent experiments, our work further investigates the localization of a small bath induced by the coupling to a large localized chain, the so-called MBL proximity effect.\r\n\r\nIn the first Chapter, we introduce a family of particle-conserving kinetically constrained models, inspired by the quantum East model.\r\nThe system we study features strong inversion-symmetry breaking, due to the nature of the correlated hopping.\r\nWe show that these models host so-called quantum Hilbert space fragmentation, consisting of disconnected subsectors in an entangled basis, and further provide an analytical description of this phenomenon.\r\nWe further probe its effect on dynamics of simple product states, showing revivals in fidelity and local observalbes.\r\nThe study of dynamics within the largest subsector reveals an anomalous transient superdiffusive behavior crossing over to slow logarithmic dynamics at later times.\r\nThis work suggests that particle conserving constrained models with inversion-symmetry breaking realize new universality classes of dynamics and invite their further theoretical and experimental studies.\r\n\r\nNext, we use kinetic constraints and disorder to design a model with many-body mobility edges in particle density.\r\nThis feature allows to study the dynamics of localized and thermal states in large systems beyond the limitations of previous studies.\r\nThe time-evolution shows typical signatures of localization at small densities, replaced by thermal behavior at larger densities.\r\nOur results provide evidence in favor of the stability of many-body mobility edges, which was recently challenged by a theoretical argument.\r\nTo support our findings, we probe the mechanism proposed as a cause of delocalization in many-body localized systems with mobility edges suggesting its ineffectiveness in the model studied.\r\n\r\nIn the last Chapter of this Thesis, we address the topic of many-body localization proximity effect.\r\nWe study a model inspired by recent experiments, featuring Anderson localized coupled to a small bath of free hard-core bosons.\r\nThe interaction among the two particle species results in non-trivial dynamics, which we probe using tensor network techniques.\r\nOur simulations show convincing evidence of many-body localization proximity effect when the bath is composed by a single free particle and interactions are strong.\r\nWe furthter observe an anomalous entanglement dynamics, which we explain through a phenomenological theory.\r\nFinally, we extract highly excited eigenstates of large systems, providing supplementary evidence in favor of our findings."}],"day":"21","oa_version":"Published Version","ec_funded":1,"project":[{"_id":"23841C26-32DE-11EA-91FC-C7463DDC885E","call_identifier":"H2020","name":"Non-Ergodic Quantum Matter: Universality, Dynamics and Control","grant_number":"850899"}],"alternative_title":["ISTA Thesis"],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","image":"/images/cc_by_nc_sa.png","name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)","short":"CC BY-NC-SA (4.0)"},"month":"03","department":[{"_id":"GradSch"},{"_id":"MaSe"}],"date_updated":"2026-04-07T13:26:32Z","title":"Ergodicity breaking in disordered and kinetically constrained quantum many-body systems","citation":{"ieee":"P. Brighi, “Ergodicity breaking in disordered and kinetically constrained quantum many-body systems,” Institute of Science and Technology Austria, 2023.","mla":"Brighi, Pietro. <i>Ergodicity Breaking in Disordered and Kinetically Constrained Quantum Many-Body Systems</i>. Institute of Science and Technology Austria, 2023, doi:<a href=\"https://doi.org/10.15479/at:ista:12732\">10.15479/at:ista:12732</a>.","ista":"Brighi P. 2023. Ergodicity breaking in disordered and kinetically constrained quantum many-body systems. Institute of Science and Technology Austria.","ama":"Brighi P. Ergodicity breaking in disordered and kinetically constrained quantum many-body systems. 2023. doi:<a href=\"https://doi.org/10.15479/at:ista:12732\">10.15479/at:ista:12732</a>","chicago":"Brighi, Pietro. “Ergodicity Breaking in Disordered and Kinetically Constrained Quantum Many-Body Systems.” Institute of Science and Technology Austria, 2023. <a href=\"https://doi.org/10.15479/at:ista:12732\">https://doi.org/10.15479/at:ista:12732</a>.","short":"P. Brighi, Ergodicity Breaking in Disordered and Kinetically Constrained Quantum Many-Body Systems, Institute of Science and Technology Austria, 2023.","apa":"Brighi, P. (2023). <i>Ergodicity breaking in disordered and kinetically constrained quantum many-body systems</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:12732\">https://doi.org/10.15479/at:ista:12732</a>"},"year":"2023","date_published":"2023-03-21T00:00:00Z","degree_awarded":"PhD","publication_status":"published","doi":"10.15479/at:ista:12732","article_processing_charge":"No","publisher":"Institute of Science and Technology Austria","publication_identifier":{"issn":["2663-337X"]}},{"oa":1,"OA_place":"publisher","_id":"12826","corr_author":"1","file_date_updated":"2023-04-20T09:26:51Z","type":"dissertation","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","author":[{"first_name":"Victoria","orcid":"0000-0001-7660-444X","last_name":"Pokusaeva","full_name":"Pokusaeva, Victoria","id":"3184041C-F248-11E8-B48F-1D18A9856A87"}],"date_created":"2023-04-14T14:56:04Z","status":"public","supervisor":[{"last_name":"Jösch","full_name":"Jösch, Maximilian A","id":"2BD278E6-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-3937-1330","first_name":"Maximilian A"}],"language":[{"iso":"eng"}],"has_accepted_license":"1","acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"}],"ddc":["570","571"],"file":[{"checksum":"5f589a9af025f7eeebfd0c186209913e","date_created":"2023-04-20T09:14:38Z","file_size":14507243,"relation":"source_file","access_level":"closed","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","file_name":"Thesis_Pokusaeva.docx","date_updated":"2023-04-20T09:26:51Z","creator":"vpokusae","file_id":"12857"},{"date_created":"2023-04-20T09:14:44Z","checksum":"bbeed76db45a996b4c91a9abe12ce0ec","success":1,"access_level":"open_access","relation":"main_file","file_size":10090711,"date_updated":"2023-04-20T09:14:44Z","file_name":"Thesis_Pokusaeva.pdf","content_type":"application/pdf","creator":"vpokusae","file_id":"12858"}],"page":"106","citation":{"apa":"Pokusaeva, V. (2023). <i>Neural control of optic flow-based navigation in Drosophila melanogaster</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:12826\">https://doi.org/10.15479/at:ista:12826</a>","short":"V. Pokusaeva, Neural Control of Optic Flow-Based Navigation in Drosophila Melanogaster, Institute of Science and Technology Austria, 2023.","chicago":"Pokusaeva, Victoria. “Neural Control of Optic Flow-Based Navigation in Drosophila Melanogaster.” Institute of Science and Technology Austria, 2023. <a href=\"https://doi.org/10.15479/at:ista:12826\">https://doi.org/10.15479/at:ista:12826</a>.","ama":"Pokusaeva V. Neural control of optic flow-based navigation in Drosophila melanogaster. 2023. doi:<a href=\"https://doi.org/10.15479/at:ista:12826\">10.15479/at:ista:12826</a>","ista":"Pokusaeva V. 2023. Neural control of optic flow-based navigation in Drosophila melanogaster. Institute of Science and Technology Austria.","mla":"Pokusaeva, Victoria. <i>Neural Control of Optic Flow-Based Navigation in Drosophila Melanogaster</i>. Institute of Science and Technology Austria, 2023, doi:<a href=\"https://doi.org/10.15479/at:ista:12826\">10.15479/at:ista:12826</a>.","ieee":"V. Pokusaeva, “Neural control of optic flow-based navigation in Drosophila melanogaster,” Institute of Science and Technology Austria, 2023."},"date_published":"2023-04-18T00:00:00Z","year":"2023","doi":"10.15479/at:ista:12826","publication_identifier":{"issn":["2663-337X"]},"article_processing_charge":"No","publisher":"Institute of Science and Technology Austria","degree_awarded":"PhD","publication_status":"published","month":"04","department":[{"_id":"MaJö"},{"_id":"GradSch"}],"date_updated":"2026-04-07T13:26:49Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"title":"Neural control of optic flow-based navigation in Drosophila melanogaster","ec_funded":1,"oa_version":"Published Version","day":"18","alternative_title":["ISTA Thesis"],"project":[{"call_identifier":"H2020","name":"International IST Doctoral Program","_id":"2564DBCA-B435-11E9-9278-68D0E5697425","grant_number":"665385"}],"abstract":[{"text":"During navigation, animals can infer the structure of the environment by computing the optic flow cues elicited by their own movements, and subsequently use this information to instruct proper locomotor actions. These computations require a panoramic assessment of the visual environment in order to disambiguate similar sensory experiences that may require distinct behavioral responses. The estimation of the global motion patterns is therefore essential for successful navigation. Yet, our understanding of the algorithms and implementations that enable coherent panoramic visual perception remains scarce. Here I pursue this problem by dissecting the functional aspects of interneuronal communication in the lobula plate tangential cell network in Drosophila melanogaster. The results presented in the thesis demonstrate that the basis for effective interpretation of the optic flow in this circuit are stereotyped synaptic connections that mediate the formation of distinct subnetworks, each extracting a particular pattern of global motion. \r\nFirstly, I show that gap junctions are essential for a correct interpretation of binocular motion cues by horizontal motion-sensitive cells. HS cells form electrical synapses with contralateral H2 neurons that are involved in detecting yaw rotation and translation. I developed an FlpStop-mediated mutant of a gap junction protein ShakB that disrupts these electrical synapses. While the loss of electrical synapses does not affect the tuning of the direction selectivity in HS neurons, it severely alters their sensitivity to horizontal motion in the contralateral side. These physiological changes result in an inappropriate integration of binocular motion cues in walking animals. While wild-type flies form a binocular perception of visual motion by non-linear integration of monocular optic flow cues, the mutant flies sum the monocular inputs linearly. These results indicate that rather than averaging signals in neighboring neurons, gap-junctions operate in conjunction with chemical synapses to mediate complex non-linear optic flow computations.\r\nSecondly, I show that stochastic manipulation of neuronal activity in the lobula plate tangential cell network is a powerful approach to study the neuronal implementation of optic flow-based navigation in flies. Tangential neurons form multiple subnetworks, each mediating course-stabilizing response to a particular global pattern of visual motion. Application of genetic mosaic techniques can provide sparse optogenetic activation of HS cells in numerous combinations. These distinct combinations of activated neurons drive an array of distinct behavioral responses, providing important insights into how visuomotor transformation is performed in the lobula plate tangential cell network. This approach can be complemented by stochastic silencing of tangential neurons, enabling direct assessment of the functional role of individual tangential neurons in the processing of specific visual motion patterns.\r\n\tTaken together, the findings presented in this thesis suggest that establishing specific activity patterns of tangential cells via stereotyped synaptic connectivity is a key to efficient optic flow-based navigation in Drosophila melanogaster.","lang":"eng"}]},{"file":[{"date_updated":"2023-08-11T10:01:34Z","file_name":"PhD_thesis_Valentini_final.zip","content_type":"application/x-zip-compressed","creator":"mvalenti","file_id":"14033","date_created":"2023-08-11T09:27:39Z","checksum":"666ee31c7eade89679806287c062fa14","access_level":"closed","relation":"source_file","file_size":56121429},{"access_level":"open_access","file_size":38199711,"relation":"main_file","date_created":"2023-08-11T14:39:17Z","checksum":"0992f2ebef152dee8e70055350ebbb55","creator":"mvalenti","file_id":"14035","file_name":"PhD_thesis_Valentini_final_validated.pdf","date_updated":"2023-08-11T14:39:17Z","content_type":"application/pdf"}],"ddc":["530"],"page":"184","supervisor":[{"last_name":"Katsaros","full_name":"Katsaros, Georgios","id":"38DB5788-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8342-202X","first_name":"Georgios"}],"status":"public","date_created":"2023-07-24T14:10:45Z","has_accepted_license":"1","acknowledged_ssus":[{"_id":"NanoFab"},{"_id":"M-Shop"}],"language":[{"iso":"eng"}],"file_date_updated":"2023-08-11T14:39:17Z","corr_author":"1","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","author":[{"first_name":"Marco","id":"C0BB2FAC-D767-11E9-B658-BC13E6697425","full_name":"Valentini, Marco","last_name":"Valentini"}],"type":"dissertation","related_material":{"record":[{"status":"public","id":"12522","relation":"research_data"},{"id":"13312","status":"public","relation":"part_of_dissertation"},{"id":"12118","status":"public","relation":"part_of_dissertation"},{"id":"8910","status":"public","relation":"part_of_dissertation"}]},"oa":1,"_id":"13286","OA_place":"publisher","abstract":[{"lang":"eng","text":"Semiconductor-superconductor hybrid systems are the harbour of many intriguing mesoscopic phenomena. This material combination leads to spatial variations of the superconducting properties, which gives rise to Andreev bound states (ABSs). Some of these states might exhibit remarkable properties that render them highly desirable for topological quantum computing. The most prominent and hunted of such states are Majorana zero modes (MZMs), quasiparticles equals to their own quasiparticles that they follow non-abelian statistics. In this thesis, we first introduce the general framework of such hybrid systems and, then, we unveil a series of mesoscopic phenomena that we discovered. Firstly, we show tunneling spectroscopy experiments on full-shell nanowires (NWs) showing that unwanted quantum-dot states coupled to superconductors (Yu-Shiba-Rusinov states) can mimic MZMs signatures. Then, we introduce a novel protocol which allowed the integration of tunneling spectroscopy with Coulomb spectroscopy within the same device. Employing this approach on both full-shell NWs and partial-shell NWs, we demonstrated that longitudinally confined states reveal charge transport phenomenology similar to the one expected for MZMs. These findings shed light on the intricate interplay between superconductivity and quantum confinement, which brought us to explore another material platform, i.e. a two-dimensional Germanium hole gas. After developing a robust way to induce superconductivity in such system, we showed how to engineer the proximity effect and we revealed a superconducting hard gap. Finally, we created a superconducting radio frequency driven ideal diode and a generator of non-sinusoidal current-phase relations. Our results open the path for the exploration of protected superconducting qubits and more complex hybrid devices in planar Germanium, like Kitaev chains and hybrid qubit devices."}],"oa_version":"Published Version","day":"21","ec_funded":1,"project":[{"_id":"262116AA-B435-11E9-9278-68D0E5697425","name":"Hybrid Semiconductor - Superconductor Quantum Devices"},{"grant_number":"862046","call_identifier":"H2020","name":"TOPOLOGICALLY PROTECTED AND SCALABLE QUANTUM BITS","_id":"237E5020-32DE-11EA-91FC-C7463DDC885E"},{"name":"Center for Correlated Quantum Materials and Solid State Quantum Systems: Conventional  and unconventional topological superconductors","_id":"34a66131-11ca-11ed-8bc3-a31681c6b03e","grant_number":"F8606"}],"alternative_title":["ISTA Thesis"],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","image":"/images/cc_by_nc_sa.png","name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)","short":"CC BY-NC-SA (4.0)"},"date_updated":"2026-04-07T13:27:22Z","month":"07","department":[{"_id":"GradSch"},{"_id":"GeKa"}],"title":"Mesoscopic phenomena in hybrid semiconductor-superconductor nanodevices : From full-shell nanowires to two-dimensional hole gas in germanium","year":"2023","date_published":"2023-07-21T00:00:00Z","citation":{"chicago":"Valentini, Marco. “Mesoscopic Phenomena in Hybrid Semiconductor-Superconductor Nanodevices : From Full-Shell Nanowires to Two-Dimensional Hole Gas in Germanium.” Institute of Science and Technology Austria, 2023. <a href=\"https://doi.org/10.15479/at:ista:13286\">https://doi.org/10.15479/at:ista:13286</a>.","ama":"Valentini M. Mesoscopic phenomena in hybrid semiconductor-superconductor nanodevices : From full-shell nanowires to two-dimensional hole gas in germanium. 2023. doi:<a href=\"https://doi.org/10.15479/at:ista:13286\">10.15479/at:ista:13286</a>","apa":"Valentini, M. (2023). <i>Mesoscopic phenomena in hybrid semiconductor-superconductor nanodevices : From full-shell nanowires to two-dimensional hole gas in germanium</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:13286\">https://doi.org/10.15479/at:ista:13286</a>","short":"M. Valentini, Mesoscopic Phenomena in Hybrid Semiconductor-Superconductor Nanodevices : From Full-Shell Nanowires to Two-Dimensional Hole Gas in Germanium, Institute of Science and Technology Austria, 2023.","mla":"Valentini, Marco. <i>Mesoscopic Phenomena in Hybrid Semiconductor-Superconductor Nanodevices : From Full-Shell Nanowires to Two-Dimensional Hole Gas in Germanium</i>. Institute of Science and Technology Austria, 2023, doi:<a href=\"https://doi.org/10.15479/at:ista:13286\">10.15479/at:ista:13286</a>.","ieee":"M. Valentini, “Mesoscopic phenomena in hybrid semiconductor-superconductor nanodevices : From full-shell nanowires to two-dimensional hole gas in germanium,” Institute of Science and Technology Austria, 2023.","ista":"Valentini M. 2023. Mesoscopic phenomena in hybrid semiconductor-superconductor nanodevices : From full-shell nanowires to two-dimensional hole gas in germanium. Institute of Science and Technology Austria."},"publication_status":"published","degree_awarded":"PhD","publisher":"Institute of Science and Technology Austria","publication_identifier":{"issn":["2663-337X"]},"article_processing_charge":"No","doi":"10.15479/at:ista:13286"},{"abstract":[{"text":"Superconductivity has many important applications ranging from levitating trains over qubits to MRI scanners. The phenomenon is successfully modeled by Bardeen-Cooper-Schrieffer (BCS) theory. From a mathematical perspective, BCS theory has been studied extensively for systems without boundary. However, little is known in the presence of boundaries. With the help of numerical methods physicists observed that the critical temperature may increase in the presence of a boundary. The goal of this thesis is to understand the influence of boundaries on the critical temperature in BCS theory and to give a first rigorous justification of these observations. On the way, we also study two-body Schrödinger operators on domains with boundaries and prove additional results for superconductors without boundary.\r\n\r\nBCS theory is based on a non-linear functional, where the minimizer indicates whether the system is superconducting or in the normal, non-superconducting state. By considering the Hessian of the BCS functional at the normal state, one can analyze whether the normal state is possibly a minimum of the BCS functional and estimate the critical temperature. The Hessian turns out to be a linear operator resembling a Schrödinger operator for two interacting particles, but with more complicated kinetic energy. As a first step, we study the two-body Schrödinger operator in the presence of boundaries.\r\nFor Neumann boundary conditions, we prove that the addition of a boundary can create new eigenvalues, which correspond to the two particles forming a bound state close to the boundary.\r\n\r\nSecond, we need to understand superconductivity in the translation invariant setting. While in three dimensions this has been extensively studied, there is no mathematical literature for the one and two dimensional cases. In dimensions one and two, we compute the weak coupling asymptotics of the critical temperature and the energy gap  in the translation invariant setting. We also prove that their ratio is independent of the microscopic details of the model in the weak coupling limit; this property is referred to as universality.\r\n\r\nIn the third part, we study the critical temperature of superconductors in the presence of boundaries. We start by considering the one-dimensional case of a half-line with contact interaction. Then, we generalize the results to generic interactions and half-spaces in one, two and three dimensions. Finally, we compare the critical temperature of a quarter space in two dimensions to the critical temperatures of a half-space and of the full space.","lang":"eng"}],"alternative_title":["ISTA Thesis"],"project":[{"grant_number":"694227","_id":"25C6DC12-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","name":"Analysis of quantum many-body systems"},{"name":"Mathematical Challenges in BCS Theory of Superconductivity","_id":"bda63fe5-d553-11ed-ba76-a16e3d2f256b","grant_number":"I06427"}],"ec_funded":1,"day":"30","oa_version":"Published Version","title":"Boundary superconductivity in BCS theory","date_updated":"2026-04-07T13:27:39Z","department":[{"_id":"GradSch"},{"_id":"RoSe"}],"month":"09","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","image":"/images/cc_by_nc_sa.png","name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)","short":"CC BY-NC-SA (4.0)"},"publisher":"Institute of Science and Technology Austria","article_processing_charge":"No","publication_identifier":{"issn":["2663-337X"]},"doi":"10.15479/at:ista:14374","degree_awarded":"PhD","publication_status":"published","date_published":"2023-09-30T00:00:00Z","year":"2023","citation":{"apa":"Roos, B. (2023). <i>Boundary superconductivity in BCS theory</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:14374\">https://doi.org/10.15479/at:ista:14374</a>","short":"B. Roos, Boundary Superconductivity in BCS Theory, Institute of Science and Technology Austria, 2023.","chicago":"Roos, Barbara. “Boundary Superconductivity in BCS Theory.” Institute of Science and Technology Austria, 2023. <a href=\"https://doi.org/10.15479/at:ista:14374\">https://doi.org/10.15479/at:ista:14374</a>.","ama":"Roos B. Boundary superconductivity in BCS theory. 2023. doi:<a href=\"https://doi.org/10.15479/at:ista:14374\">10.15479/at:ista:14374</a>","ista":"Roos B. 2023. Boundary superconductivity in BCS theory. Institute of Science and Technology Austria.","mla":"Roos, Barbara. <i>Boundary Superconductivity in BCS Theory</i>. Institute of Science and Technology Austria, 2023, doi:<a href=\"https://doi.org/10.15479/at:ista:14374\">10.15479/at:ista:14374</a>.","ieee":"B. Roos, “Boundary superconductivity in BCS theory,” Institute of Science and Technology Austria, 2023."},"page":"206","ddc":["515","539"],"file":[{"file_name":"phd-thesis-draft_pdfa_acrobat.pdf","date_updated":"2023-10-06T11:35:56Z","content_type":"application/pdf","creator":"broos","file_id":"14398","date_created":"2023-10-06T11:35:56Z","checksum":"ef039ffc3de2cb8dee5b14110938e9b6","access_level":"open_access","relation":"main_file","file_size":2365702},{"access_level":"closed","file_size":4691734,"relation":"source_file","date_created":"2023-10-06T11:38:01Z","checksum":"81dcac33daeefaf0111db52f41bb1fd0","file_id":"14399","creator":"broos","file_name":"Version5.zip","date_updated":"2023-10-06T11:38:01Z","content_type":"application/x-zip-compressed"}],"language":[{"iso":"eng"}],"has_accepted_license":"1","date_created":"2023-09-28T14:23:04Z","status":"public","supervisor":[{"orcid":"0000-0002-6781-0521","first_name":"Robert","last_name":"Seiringer","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","full_name":"Seiringer, Robert"}],"author":[{"last_name":"Roos","id":"5DA90512-D80F-11E9-8994-2E2EE6697425","full_name":"Roos, Barbara","orcid":"0000-0002-9071-5880","first_name":"Barbara"}],"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","type":"dissertation","corr_author":"1","file_date_updated":"2023-10-06T11:38:01Z","_id":"14374","OA_place":"publisher","related_material":{"record":[{"status":"public","id":"10850","relation":"part_of_dissertation"},{"id":"13207","status":"public","relation":"part_of_dissertation"}]},"oa":1},{"article_number":"2306.07109","title":"Radio frequency driven superconducting diode and parity conserving  Cooper pair transport in a two-dimensional germanium hole gas","department":[{"_id":"GeKa"},{"_id":"M-Shop"}],"month":"06","date_updated":"2026-04-07T13:27:22Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"doi":"10.48550/arXiv.2306.07109","article_processing_charge":"No","publication_status":"draft","citation":{"short":"M. Valentini, O. Sagi, L. Baghumyan, T. de Gijsel, J. Jung, S. Calcaterra, A. Ballabio, J.A. Servin, K. Aggarwal, M. Janik, T. Adletzberger, R.S. Souto, M. Leijnse, J. Danon, C. Schrade, E. Bakkers, D. Chrastina, G. Isella, G. Katsaros, ArXiv (n.d.).","apa":"Valentini, M., Sagi, O., Baghumyan, L., Gijsel, T. de, Jung, J., Calcaterra, S., … Katsaros, G. (n.d.). Radio frequency driven superconducting diode and parity conserving  Cooper pair transport in a two-dimensional germanium hole gas. <i>arXiv</i>. <a href=\"https://doi.org/10.48550/arXiv.2306.07109\">https://doi.org/10.48550/arXiv.2306.07109</a>","ama":"Valentini M, Sagi O, Baghumyan L, et al. Radio frequency driven superconducting diode and parity conserving  Cooper pair transport in a two-dimensional germanium hole gas. <i>arXiv</i>. doi:<a href=\"https://doi.org/10.48550/arXiv.2306.07109\">10.48550/arXiv.2306.07109</a>","chicago":"Valentini, Marco, Oliver Sagi, Levon Baghumyan, Thijs de Gijsel, Jason Jung, Stefano Calcaterra, Andrea Ballabio, et al. “Radio Frequency Driven Superconducting Diode and Parity Conserving  Cooper Pair Transport in a Two-Dimensional Germanium Hole Gas.” <i>ArXiv</i>, n.d. <a href=\"https://doi.org/10.48550/arXiv.2306.07109\">https://doi.org/10.48550/arXiv.2306.07109</a>.","ista":"Valentini M, Sagi O, Baghumyan L, Gijsel T de, Jung J, Calcaterra S, Ballabio A, Servin JA, Aggarwal K, Janik M, Adletzberger T, Souto RS, Leijnse M, Danon J, Schrade C, Bakkers E, Chrastina D, Isella G, Katsaros G. Radio frequency driven superconducting diode and parity conserving  Cooper pair transport in a two-dimensional germanium hole gas. arXiv, 2306.07109.","ieee":"M. Valentini <i>et al.</i>, “Radio frequency driven superconducting diode and parity conserving  Cooper pair transport in a two-dimensional germanium hole gas,” <i>arXiv</i>. .","mla":"Valentini, Marco, et al. “Radio Frequency Driven Superconducting Diode and Parity Conserving  Cooper Pair Transport in a Two-Dimensional Germanium Hole Gas.” <i>ArXiv</i>, 2306.07109, doi:<a href=\"https://doi.org/10.48550/arXiv.2306.07109\">10.48550/arXiv.2306.07109</a>."},"date_published":"2023-06-13T00:00:00Z","year":"2023","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2306.07109","open_access":"1"}],"abstract":[{"lang":"eng","text":"Superconductor/semiconductor hybrid devices have attracted increasing\r\ninterest in the past years. Superconducting electronics aims to complement\r\nsemiconductor technology, while hybrid architectures are at the forefront of\r\nnew ideas such as topological superconductivity and protected qubits. In this\r\nwork, we engineer the induced superconductivity in two-dimensional germanium\r\nhole gas by varying the distance between the quantum well and the aluminum. We\r\ndemonstrate a hard superconducting gap and realize an electrically and flux\r\ntunable superconducting diode using a superconducting quantum interference\r\ndevice (SQUID). This allows to tune the current phase relation (CPR), to a\r\nregime where single Cooper pair tunneling is suppressed, creating a $ \\sin\r\n\\left( 2 \\varphi \\right)$ CPR. Shapiro experiments complement this\r\ninterpretation and the microwave drive allows to create a diode with $ \\approx\r\n100 \\%$ efficiency. The reported results open up the path towards monolithic\r\nintegration of spin qubit devices, microwave resonators and (protected)\r\nsuperconducting qubits on a silicon technology compatible platform."}],"project":[{"grant_number":"862046","call_identifier":"H2020","_id":"237E5020-32DE-11EA-91FC-C7463DDC885E","name":"TOPOLOGICALLY PROTECTED AND SCALABLE QUANTUM BITS"},{"call_identifier":"FWF","name":"Towards scalable hut wire quantum devices","_id":"237B3DA4-32DE-11EA-91FC-C7463DDC885E","grant_number":"P32235"},{"grant_number":"P36507","_id":"bd8bd29e-d553-11ed-ba76-f0070d4b237a","name":"Merging spin and superconducting qubits in planar Ge"},{"grant_number":"F8606","name":"Center for Correlated Quantum Materials and Solid State Quantum Systems: Conventional  and unconventional topological superconductors","_id":"34a66131-11ca-11ed-8bc3-a31681c6b03e"},{"name":"Protected states of quantum matter","_id":"eb9b30ac-77a9-11ec-83b8-871f581d53d2"}],"external_id":{"arxiv":["2306.07109"]},"ec_funded":1,"oa_version":"Preprint","day":"13","type":"preprint","acknowledgement":"The authors acknowledge Alexander Brinkmann, Alessandro Crippa, Andrew Higginbotham, Andrea Iorio, Giordano\r\nScappucci and Christian Schonenberger for helpful discussions. We thank Marcel Verheijen for the support in the\r\nTEM analysis. This research and related results were made\r\npossible with the support of the NOMIS Foundation. It was\r\nsupported by the Scientific Service Units of ISTA through resources provided by the MIBA Machine Shop and the\r\nnanofabrication facility, the European Union’s Horizon 2020\r\nresearch and innovation programme under Grant Agreement\r\nNo 862046, the HORIZON-RIA 101069515 project and the\r\nFWF Projects #P-32235, #P-36507 and #F-8606. R.S.S.\r\nacknowledges Spanish CM “Talento Program” Project No.\r\n2022-T1/IND-24070.","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"last_name":"Valentini","full_name":"Valentini, Marco","id":"C0BB2FAC-D767-11E9-B658-BC13E6697425","first_name":"Marco"},{"first_name":"Oliver","last_name":"Sagi","full_name":"Sagi, Oliver","id":"71616374-A8E9-11E9-A7CA-09ECE5697425"},{"full_name":"Baghumyan, Levon","last_name":"Baghumyan","first_name":"Levon"},{"full_name":"Gijsel, Thijs de","last_name":"Gijsel","first_name":"Thijs de"},{"first_name":"Jason","last_name":"Jung","id":"4C9ACE7A-F248-11E8-B48F-1D18A9856A87","full_name":"Jung, Jason"},{"first_name":"Stefano","full_name":"Calcaterra, Stefano","last_name":"Calcaterra"},{"first_name":"Andrea","last_name":"Ballabio","full_name":"Ballabio, Andrea"},{"full_name":"Servin, Juan Aguilera","last_name":"Servin","first_name":"Juan Aguilera"},{"id":"b22ab905-3539-11eb-84c3-fc159dcd79cb","full_name":"Aggarwal, Kushagra","last_name":"Aggarwal","first_name":"Kushagra","orcid":"0000-0001-9985-9293"},{"first_name":"Marian","orcid":"0009-0003-9037-8831","id":"396A1950-F248-11E8-B48F-1D18A9856A87","full_name":"Janik, Marian","last_name":"Janik"},{"first_name":"Thomas","last_name":"Adletzberger","full_name":"Adletzberger, Thomas","id":"38756BB2-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Rubén Seoane","last_name":"Souto","full_name":"Souto, Rubén Seoane"},{"first_name":"Martin","last_name":"Leijnse","full_name":"Leijnse, Martin"},{"first_name":"Jeroen","full_name":"Danon, Jeroen","last_name":"Danon"},{"first_name":"Constantin","full_name":"Schrade, Constantin","last_name":"Schrade"},{"first_name":"Erik","last_name":"Bakkers","full_name":"Bakkers, Erik"},{"first_name":"Daniel","last_name":"Chrastina","full_name":"Chrastina, Daniel"},{"first_name":"Giovanni","full_name":"Isella, Giovanni","last_name":"Isella"},{"orcid":"0000-0001-8342-202X","first_name":"Georgios","last_name":"Katsaros","id":"38DB5788-F248-11E8-B48F-1D18A9856A87","full_name":"Katsaros, Georgios"}],"corr_author":"1","arxiv":1,"OA_place":"repository","_id":"13312","related_material":{"record":[{"relation":"dissertation_contains","status":"public","id":"13286"}]},"oa":1,"ddc":["530"],"language":[{"iso":"eng"}],"publication":"arXiv","acknowledged_ssus":[{"_id":"M-Shop"},{"_id":"NanoFab"}],"keyword":["Mesoscale and Nanoscale Physics"],"date_created":"2023-07-26T11:17:20Z","status":"public"},{"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","author":[{"first_name":"Christian","full_name":"Hainzl, Christian","last_name":"Hainzl"},{"full_name":"Roos, Barbara","id":"5DA90512-D80F-11E9-8994-2E2EE6697425","last_name":"Roos","first_name":"Barbara","orcid":"0000-0002-9071-5880"},{"last_name":"Seiringer","full_name":"Seiringer, Robert","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6781-0521","first_name":"Robert"}],"acknowledgement":"We thank Egor Babaev for encouraging us to study this problem, and Rupert Frank for many fruitful discussions. scussions. Funding. Funding from the European Union’s Horizon 2020 research and innovation programme under the ERC grant agreement No. 694227 (Barbara Roos and Robert Seiringer) is gratefully acknowledged.","type":"journal_article","corr_author":"1","issue":"4","file_date_updated":"2023-07-11T08:19:15Z","arxiv":1,"_id":"13207","related_material":{"record":[{"relation":"dissertation_contains","status":"public","id":"14374"}]},"oa":1,"intvolume":"        12","page":"1507–1540","ddc":["530"],"file":[{"access_level":"open_access","success":1,"file_size":304619,"relation":"main_file","date_created":"2023-07-11T08:19:15Z","checksum":"5501da33be010b5c81440438287584d5","file_id":"13208","creator":"alisjak","file_name":"2023_EMS_Hainzl.pdf","date_updated":"2023-07-11T08:19:15Z","content_type":"application/pdf"}],"publication":"Journal of Spectral Theory","language":[{"iso":"eng"}],"has_accepted_license":"1","date_created":"2023-07-10T16:35:45Z","scopus_import":"1","status":"public","isi":1,"title":"Boundary superconductivity in the BCS model","date_updated":"2026-04-07T13:27:39Z","month":"05","department":[{"_id":"GradSch"},{"_id":"RoSe"}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"publisher":"EMS Press","publication_identifier":{"eissn":["1664-0403"],"issn":["1664-039X"]},"article_processing_charge":"No","doi":"10.4171/JST/439","publication_status":"published","date_published":"2023-05-18T00:00:00Z","year":"2023","citation":{"chicago":"Hainzl, Christian, Barbara Roos, and Robert Seiringer. “Boundary Superconductivity in the BCS Model.” <i>Journal of Spectral Theory</i>. EMS Press, 2023. <a href=\"https://doi.org/10.4171/JST/439\">https://doi.org/10.4171/JST/439</a>.","ama":"Hainzl C, Roos B, Seiringer R. Boundary superconductivity in the BCS model. <i>Journal of Spectral Theory</i>. 2023;12(4):1507–1540. doi:<a href=\"https://doi.org/10.4171/JST/439\">10.4171/JST/439</a>","apa":"Hainzl, C., Roos, B., &#38; Seiringer, R. (2023). Boundary superconductivity in the BCS model. <i>Journal of Spectral Theory</i>. EMS Press. <a href=\"https://doi.org/10.4171/JST/439\">https://doi.org/10.4171/JST/439</a>","short":"C. Hainzl, B. Roos, R. Seiringer, Journal of Spectral Theory 12 (2023) 1507–1540.","mla":"Hainzl, Christian, et al. “Boundary Superconductivity in the BCS Model.” <i>Journal of Spectral Theory</i>, vol. 12, no. 4, EMS Press, 2023, pp. 1507–1540, doi:<a href=\"https://doi.org/10.4171/JST/439\">10.4171/JST/439</a>.","ieee":"C. Hainzl, B. Roos, and R. Seiringer, “Boundary superconductivity in the BCS model,” <i>Journal of Spectral Theory</i>, vol. 12, no. 4. EMS Press, pp. 1507–1540, 2023.","ista":"Hainzl C, Roos B, Seiringer R. 2023. Boundary superconductivity in the BCS model. Journal of Spectral Theory. 12(4), 1507–1540."},"article_type":"original","abstract":[{"lang":"eng","text":"We consider the linear BCS equation, determining the BCS critical temperature, in the presence of a boundary, where Dirichlet boundary conditions are imposed. In the one-dimensional case with point interactions, we prove that the critical temperature is strictly larger than the bulk value, at least at weak coupling. In particular, the Cooper-pair wave function localizes near the boundary, an effect that cannot be modeled by effective Neumann boundary conditions on the order parameter as often imposed in Ginzburg–Landau theory. We also show that the relative shift in critical temperature vanishes if the coupling constant either goes to zero or to infinity."}],"quality_controlled":"1","external_id":{"arxiv":["2201.08090"],"isi":["000997933500008"]},"project":[{"grant_number":"694227","_id":"25C6DC12-B435-11E9-9278-68D0E5697425","name":"Analysis of quantum many-body systems","call_identifier":"H2020"}],"ec_funded":1,"day":"18","volume":12,"oa_version":"Published Version"},{"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","image":"/images/cc_by_nc_sa.png","name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)","short":"CC BY-NC-SA (4.0)"},"month":"11","department":[{"_id":"KrCh"},{"_id":"GradSch"}],"date_updated":"2026-04-07T13:27:56Z","title":"Automated verification and control of infinite state stochastic systems","citation":{"apa":"Zikelic, D. (2023). <i>Automated verification and control of infinite state stochastic systems</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/14539\">https://doi.org/10.15479/14539</a>","short":"D. Zikelic, Automated Verification and Control of Infinite State Stochastic Systems, Institute of Science and Technology Austria, 2023.","chicago":"Zikelic, Dorde. “Automated Verification and Control of Infinite State Stochastic Systems.” Institute of Science and Technology Austria, 2023. <a href=\"https://doi.org/10.15479/14539\">https://doi.org/10.15479/14539</a>.","ama":"Zikelic D. Automated verification and control of infinite state stochastic systems. 2023. doi:<a href=\"https://doi.org/10.15479/14539\">10.15479/14539</a>","ista":"Zikelic D. 2023. Automated verification and control of infinite state stochastic systems. Institute of Science and Technology Austria.","mla":"Zikelic, Dorde. <i>Automated Verification and Control of Infinite State Stochastic Systems</i>. Institute of Science and Technology Austria, 2023, doi:<a href=\"https://doi.org/10.15479/14539\">10.15479/14539</a>.","ieee":"D. Zikelic, “Automated verification and control of infinite state stochastic systems,” Institute of Science and Technology Austria, 2023."},"year":"2023","date_published":"2023-11-15T00:00:00Z","publication_status":"published","degree_awarded":"PhD","doi":"10.15479/14539","publication_identifier":{"issn":["2663-337X"],"isbn":["978-3-99078-036-7"]},"article_processing_charge":"No","publisher":"Institute of Science and Technology Austria","abstract":[{"lang":"eng","text":"Stochastic systems provide a formal framework for modelling and quantifying uncertainty in systems and have been widely adopted in many application domains. Formal\r\nverification and control of finite state stochastic systems, a subfield of formal methods\r\nalso known as probabilistic model checking, is well studied. In contrast, formal verification and control of infinite state stochastic systems have received comparatively\r\nless attention. However, infinite state stochastic systems commonly arise in practice.\r\nFor instance, probabilistic models that contain continuous probability distributions such\r\nas normal or uniform, or stochastic dynamical systems which are a classical model for\r\ncontrol under uncertainty, both give rise to infinite state systems.\r\nThe goal of this thesis is to contribute to laying theoretical and algorithmic foundations\r\nof fully automated formal verification and control of infinite state stochastic systems,\r\nwith a particular focus on systems that may be executed over a long or infinite time.\r\nWe consider formal verification of infinite state stochastic systems in the setting of\r\nstatic analysis of probabilistic programs and formal control in the setting of controller\r\nsynthesis in stochastic dynamical systems. For both problems, we present some of the\r\nfirst fully automated methods for probabilistic (a.k.a. quantitative) reachability and\r\nsafety analysis applicable to infinite time horizon systems. We also advance the state\r\nof the art of probability 1 (a.k.a. qualitative) reachability analysis for both problems.\r\nFinally, for formal controller synthesis in stochastic dynamical systems, we present a\r\nnovel framework for learning neural network control policies in stochastic dynamical\r\nsystems with formal guarantees on correctness with respect to quantitative reachability,\r\nsafety or reach-avoid specifications.\r\n"}],"oa_version":"Published Version","day":"15","ec_funded":1,"project":[{"name":"Formal Methods for Stochastic Models: Algorithms and Applications","call_identifier":"H2020","_id":"0599E47C-7A3F-11EA-A408-12923DDC885E","grant_number":"863818"},{"grant_number":"665385","call_identifier":"H2020","name":"International IST Doctoral Program","_id":"2564DBCA-B435-11E9-9278-68D0E5697425"}],"alternative_title":["ISTA Thesis"],"file_date_updated":"2023-11-15T13:44:24Z","corr_author":"1","type":"dissertation","author":[{"first_name":"Dorde","orcid":"0000-0002-4681-1699","id":"294AA7A6-F248-11E8-B48F-1D18A9856A87","full_name":"Zikelic, Dorde","last_name":"Zikelic"}],"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","oa":1,"related_material":{"record":[{"relation":"part_of_dissertation","id":"10414","status":"public"},{"id":"12000","status":"public","relation":"part_of_dissertation"},{"id":"9644","status":"public","relation":"part_of_dissertation"},{"relation":"part_of_dissertation","id":"12511","status":"public"},{"status":"public","id":"14600","relation":"part_of_dissertation"},{"id":"14601","status":"public","relation":"part_of_dissertation"},{"relation":"part_of_dissertation","id":"1194","status":"public"}]},"OA_place":"publisher","_id":"14539","file":[{"file_name":"main.pdf","date_updated":"2023-11-15T13:43:28Z","content_type":"application/pdf","creator":"cchlebak","file_id":"14540","date_created":"2023-11-15T13:43:28Z","checksum":"f23e002b0059ca78e1fbb864da52dd7e","access_level":"open_access","success":1,"relation":"main_file","file_size":2116426},{"date_created":"2023-11-15T13:44:24Z","checksum":"80ca37618a3c7b59866875f8be9b15ed","access_level":"closed","relation":"source_file","file_size":35884057,"file_name":"thesis_source.zip","date_updated":"2023-11-15T13:44:24Z","content_type":"application/x-zip-compressed","creator":"cchlebak","file_id":"14541"}],"ddc":["000"],"page":"256","supervisor":[{"id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","full_name":"Chatterjee, Krishnendu","last_name":"Chatterjee","orcid":"0000-0002-4561-241X","first_name":"Krishnendu"}],"status":"public","date_created":"2023-11-15T13:39:10Z","language":[{"iso":"eng"}]}]