[{"quality_controlled":"1","license":"https://creativecommons.org/licenses/by/4.0/","keyword":["Nuclear and High Energy Physics"],"isi":1,"year":"2023","external_id":{"isi":["000967947300001"]},"file":[{"file_size":855494,"relation":"main_file","access_level":"open_access","date_updated":"2024-01-09T08:59:24Z","file_name":"2023_PhysicsLettersB_Faccioli.pdf","checksum":"02dec160dbc81d95985e755869d8afbf","success":1,"creator":"dernst","content_type":"application/pdf","file_id":"14762","date_created":"2024-01-09T08:59:24Z"}],"abstract":[{"text":"Several fixed-target experiments reported J/ψ and ϒ polarizations, as functions of Feynman x (xF) and transverse momentum (PT), in three different frames, using different combinations of beam particles, target nuclei, and collision energies. Despite the diverse and heterogeneous picture formed by these measurements, a detailed look allows us to discern qualitative physical patterns that inspire a simple empirical model. This data-driven scenario offers a good quantitative description of the J/ψ and ϒ(1S) polarizations measured in proton- and pion-nucleus collisions, in the xF 0.5 domain: more than 80 data points (not statistically independent) are well reproduced with only one free parameter. This study sets the context for future low-PT\r\n quarkonium polarization measurements in proton- and pion-nucleus collisions, such as those to be made by the AMBER experiment, and shows that such measurements provide significant constraints on the poorly-known parton distribution functions of the pion.","lang":"eng"}],"article_number":"137871","intvolume":"       840","oa_version":"Published Version","language":[{"iso":"eng"}],"date_updated":"2025-09-09T14:13:46Z","title":"Low-pT quarkonium polarization measurements: Challenges and opportunities","day":"10","file_date_updated":"2024-01-09T08:59:24Z","doi":"10.1016/j.physletb.2023.137871","status":"public","type":"journal_article","acknowledgement":"P.F. and C.L. acknowledge support from Fundação para a Ciência e a Tecnologia, Portugal, under contract CERN/FIS-PAR/0010/2019.\r\nOpen Access funded by SCOAP3.","date_created":"2024-01-08T13:09:17Z","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"ddc":["530"],"author":[{"full_name":"Faccioli, Pietro","first_name":"Pietro","last_name":"Faccioli"},{"full_name":"Krätschmer, Ilse","id":"30d4014e-7753-11eb-b44b-db6d61112e73","first_name":"Ilse","last_name":"Krätschmer","orcid":"0000-0002-5636-9259"},{"full_name":"Lourenço, Carlos","first_name":"Carlos","last_name":"Lourenço"}],"article_type":"original","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","month":"05","date_published":"2023-05-10T00:00:00Z","publication_status":"published","citation":{"mla":"Faccioli, Pietro, et al. “Low-PT Quarkonium Polarization Measurements: Challenges and Opportunities.” <i>Physics Letters B</i>, vol. 840, 137871, Elsevier, 2023, doi:<a href=\"https://doi.org/10.1016/j.physletb.2023.137871\">10.1016/j.physletb.2023.137871</a>.","ista":"Faccioli P, Krätschmer I, Lourenço C. 2023. Low-pT quarkonium polarization measurements: Challenges and opportunities. Physics Letters B. 840, 137871.","apa":"Faccioli, P., Krätschmer, I., &#38; Lourenço, C. (2023). Low-pT quarkonium polarization measurements: Challenges and opportunities. <i>Physics Letters B</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.physletb.2023.137871\">https://doi.org/10.1016/j.physletb.2023.137871</a>","short":"P. Faccioli, I. Krätschmer, C. Lourenço, Physics Letters B 840 (2023).","ieee":"P. Faccioli, I. Krätschmer, and C. Lourenço, “Low-pT quarkonium polarization measurements: Challenges and opportunities,” <i>Physics Letters B</i>, vol. 840. Elsevier, 2023.","ama":"Faccioli P, Krätschmer I, Lourenço C. Low-pT quarkonium polarization measurements: Challenges and opportunities. <i>Physics Letters B</i>. 2023;840. doi:<a href=\"https://doi.org/10.1016/j.physletb.2023.137871\">10.1016/j.physletb.2023.137871</a>","chicago":"Faccioli, Pietro, Ilse Krätschmer, and Carlos Lourenço. “Low-PT Quarkonium Polarization Measurements: Challenges and Opportunities.” <i>Physics Letters B</i>. Elsevier, 2023. <a href=\"https://doi.org/10.1016/j.physletb.2023.137871\">https://doi.org/10.1016/j.physletb.2023.137871</a>."},"volume":840,"department":[{"_id":"MaRo"}],"article_processing_charge":"Yes (via OA deal)","has_accepted_license":"1","oa":1,"publication_identifier":{"eissn":["1873-2445"],"issn":["0370-2693"]},"_id":"14753","publication":"Physics Letters B","scopus_import":"1","publisher":"Elsevier","fulldoi":"https://doi.org/10.1016/j.physletb.2023.137871"},{"has_accepted_license":"1","oa":1,"publisher":"The Royal Society","scopus_import":"1","fulldoi":"https://doi.org/10.1098/rsta.2022.0112","_id":"14754","pmid":1,"publication_identifier":{"issn":["1364-503X"],"eissn":["1471-2962"]},"publication":"Philosophical Transactions of the Royal Society A","month":"05","publication_status":"published","date_published":"2023-05-01T00:00:00Z","article_type":"original","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","department":[{"_id":"BjHo"}],"article_processing_charge":"No","citation":{"ama":"Wang B, Mellibovsky F, Ayats López R, Deguchi K, Meseguer A. Mean structure of the supercritical turbulent spiral in Taylor–Couette flow. <i>Philosophical Transactions of the Royal Society A</i>. 2023;381(2246). doi:<a href=\"https://doi.org/10.1098/rsta.2022.0112\">10.1098/rsta.2022.0112</a>","chicago":"Wang, B., F. Mellibovsky, Roger Ayats López, K. Deguchi, and A. Meseguer. “Mean Structure of the Supercritical Turbulent Spiral in Taylor–Couette Flow.” <i>Philosophical Transactions of the Royal Society A</i>. The Royal Society, 2023. <a href=\"https://doi.org/10.1098/rsta.2022.0112\">https://doi.org/10.1098/rsta.2022.0112</a>.","ieee":"B. Wang, F. Mellibovsky, R. Ayats López, K. Deguchi, and A. Meseguer, “Mean structure of the supercritical turbulent spiral in Taylor–Couette flow,” <i>Philosophical Transactions of the Royal Society A</i>, vol. 381, no. 2246. The Royal Society, 2023.","ista":"Wang B, Mellibovsky F, Ayats López R, Deguchi K, Meseguer A. 2023. Mean structure of the supercritical turbulent spiral in Taylor–Couette flow. Philosophical Transactions of the Royal Society A. 381(2246), 0112.","apa":"Wang, B., Mellibovsky, F., Ayats López, R., Deguchi, K., &#38; Meseguer, A. (2023). Mean structure of the supercritical turbulent spiral in Taylor–Couette flow. <i>Philosophical Transactions of the Royal Society A</i>. The Royal Society. <a href=\"https://doi.org/10.1098/rsta.2022.0112\">https://doi.org/10.1098/rsta.2022.0112</a>","mla":"Wang, B., et al. “Mean Structure of the Supercritical Turbulent Spiral in Taylor–Couette Flow.” <i>Philosophical Transactions of the Royal Society A</i>, vol. 381, no. 2246, 0112, The Royal Society, 2023, doi:<a href=\"https://doi.org/10.1098/rsta.2022.0112\">10.1098/rsta.2022.0112</a>.","short":"B. Wang, F. Mellibovsky, R. Ayats López, K. Deguchi, A. Meseguer, Philosophical Transactions of the Royal Society A 381 (2023)."},"volume":381,"doi":"10.1098/rsta.2022.0112","file_date_updated":"2024-01-09T09:13:53Z","status":"public","type":"journal_article","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"ddc":["530"],"author":[{"full_name":"Wang, B.","last_name":"Wang","first_name":"B."},{"first_name":"F.","last_name":"Mellibovsky","full_name":"Mellibovsky, F."},{"last_name":"Ayats López","orcid":"0000-0001-6572-0621","first_name":"Roger","id":"ab77522d-073b-11ed-8aff-e71b39258362","full_name":"Ayats López, Roger"},{"first_name":"K.","last_name":"Deguchi","full_name":"Deguchi, K."},{"last_name":"Meseguer","first_name":"A.","full_name":"Meseguer, A."}],"issue":"2246","acknowledgement":"K.D.’s research was supported by Australian Research Council Discovery Early Career Researcher Award (DE170100171). B.W., R.A., F.M. and A.M. research was supported by the Spanish Ministerio de Economía y Competitividad (grant nos. FIS2016-77849-R and FIS2017-85794-P) and Ministerio de Ciencia e Innovación (grant no. PID2020-114043GB-I00) and the Generalitat de Catalunya (grant no. 2017-SGR-785). B.W.’s research was also supported by the Chinese Scholarship Council (grant CSC no. 201806440152). F.M. is a Serra-Húnter Fellow.","date_created":"2024-01-08T13:11:45Z","year":"2023","external_id":{"pmid":["36907214"],"isi":["000947761800008"]},"quality_controlled":"1","keyword":["General Physics and Astronomy","General Engineering","General Mathematics"],"isi":1,"oa_version":"Submitted Version","language":[{"iso":"eng"}],"title":"Mean structure of the supercritical turbulent spiral in Taylor–Couette flow","date_updated":"2025-09-09T14:14:17Z","day":"01","file":[{"relation":"main_file","file_size":6421086,"date_created":"2024-01-09T09:13:53Z","file_id":"14763","checksum":"1978d126c0ce2f47c22ac20107cc0106","content_type":"application/pdf","creator":"dernst","success":1,"file_name":"2023_PhilTransactionsA_Wang_accepted.pdf","date_updated":"2024-01-09T09:13:53Z","access_level":"open_access"}],"article_number":"0112","abstract":[{"text":"The large-scale laminar/turbulent spiral patterns that appear in the linearly unstable regime of counter-rotating Taylor–Couette flow are investigated from a statistical perspective by means of direct numerical simulation. Unlike the vast majority of previous numerical studies, we analyse the flow in periodic parallelogram-annular domains, following a coordinate change that aligns one of the parallelogram sides with the spiral pattern. The domain size, shape and spatial resolution have been varied and the results compared with those in a sufficiently large computational orthogonal domain with natural axial and azimuthal periodicity. We find that a minimal parallelogram of the right tilt significantly reduces the computational cost without notably compromising the statistical properties of the supercritical turbulent spiral. Its mean structure, obtained from extremely long time integrations in a co-rotating reference frame using the method of slices, bears remarkable similarity with the turbulent stripes observed in plane Couette flow, the centrifugal instability playing only a secondary role.","lang":"eng"}],"intvolume":"       381"},{"arxiv":1,"oa":1,"fulldoi":"https://doi.org/10.3233/asy-221775","publisher":"IOS Press","scopus_import":"1","publication":"Asymptotic Analysis","publication_identifier":{"issn":["0921-7134"],"eissn":["1875-8576"]},"_id":"14755","publication_status":"published","date_published":"2023-02-02T00:00:00Z","month":"02","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","article_type":"original","department":[{"_id":"JuFi"}],"article_processing_charge":"No","volume":131,"citation":{"ieee":"M. Moser, “Convergence of the scalar- and vector-valued Allen–Cahn equation to mean curvature flow with 90°-contact angle in higher dimensions, part I: Convergence result,” <i>Asymptotic Analysis</i>, vol. 131, no. 3–4. IOS Press, pp. 297–383, 2023.","short":"M. Moser, Asymptotic Analysis 131 (2023) 297–383.","ista":"Moser M. 2023. Convergence of the scalar- and vector-valued Allen–Cahn equation to mean curvature flow with 90°-contact angle in higher dimensions, part I: Convergence result. Asymptotic Analysis. 131(3–4), 297–383.","mla":"Moser, Maximilian. “Convergence of the Scalar- and Vector-Valued Allen–Cahn Equation to Mean Curvature Flow with 90°-Contact Angle in Higher Dimensions, Part I: Convergence Result.” <i>Asymptotic Analysis</i>, vol. 131, no. 3–4, IOS Press, 2023, pp. 297–383, doi:<a href=\"https://doi.org/10.3233/asy-221775\">10.3233/asy-221775</a>.","apa":"Moser, M. (2023). Convergence of the scalar- and vector-valued Allen–Cahn equation to mean curvature flow with 90°-contact angle in higher dimensions, part I: Convergence result. <i>Asymptotic Analysis</i>. IOS Press. <a href=\"https://doi.org/10.3233/asy-221775\">https://doi.org/10.3233/asy-221775</a>","ama":"Moser M. Convergence of the scalar- and vector-valued Allen–Cahn equation to mean curvature flow with 90°-contact angle in higher dimensions, part I: Convergence result. <i>Asymptotic Analysis</i>. 2023;131(3-4):297-383. doi:<a href=\"https://doi.org/10.3233/asy-221775\">10.3233/asy-221775</a>","chicago":"Moser, Maximilian. “Convergence of the Scalar- and Vector-Valued Allen–Cahn Equation to Mean Curvature Flow with 90°-Contact Angle in Higher Dimensions, Part I: Convergence Result.” <i>Asymptotic Analysis</i>. IOS Press, 2023. <a href=\"https://doi.org/10.3233/asy-221775\">https://doi.org/10.3233/asy-221775</a>."},"type":"journal_article","status":"public","doi":"10.3233/asy-221775","author":[{"full_name":"Moser, Maximilian","id":"a60047a9-da77-11eb-85b4-c4dc385ebb8c","first_name":"Maximilian","last_name":"Moser"}],"corr_author":"1","date_created":"2024-01-08T13:13:28Z","issue":"3-4","acknowledgement":"The author gratefully acknowledges support through DFG, GRK 1692 “Curvature,\r\nCycles and Cohomology” during parts of the work.","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2105.07100","open_access":"1"}],"external_id":{"arxiv":["2105.07100"],"isi":["000927801300001"]},"year":"2023","page":"297-383","keyword":["General Mathematics"],"isi":1,"quality_controlled":"1","date_updated":"2025-09-09T14:14:55Z","title":"Convergence of the scalar- and vector-valued Allen–Cahn equation to mean curvature flow with 90°-contact angle in higher dimensions, part I: Convergence result","day":"02","oa_version":"Preprint","language":[{"iso":"eng"}],"intvolume":"       131","abstract":[{"lang":"eng","text":"We consider the sharp interface limit for the scalar-valued and vector-valued Allen–Cahn equation with homogeneous Neumann boundary condition in a bounded smooth domain Ω of arbitrary dimension N ⩾ 2 in the situation when a two-phase diffuse interface has developed and intersects the boundary ∂ Ω. The limit problem is mean curvature flow with 90°-contact angle and we show convergence in strong norms for well-prepared initial data as long as a smooth solution to the limit problem exists. To this end we assume that the limit problem has a smooth solution on [ 0 , T ] for some time T &gt; 0. Based on the latter we construct suitable curvilinear coordinates and set up an asymptotic expansion for the scalar-valued and the vector-valued Allen–Cahn equation. In order to estimate the difference of the exact and approximate solutions with a Gronwall-type argument, a spectral estimate for the linearized Allen–Cahn operator in both cases is required. The latter will be shown in a separate paper, cf. (Moser (2021))."}]},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","page":"169-191","quality_controlled":"1","editor":[{"last_name":"Huttner","first_name":"Wieland","full_name":"Huttner, Wieland"}],"publication_status":"published","date_published":"2023-08-08T00:00:00Z","month":"08","year":"2023","abstract":[{"text":"The cerebral cortex is comprised of a vast cell-type diversity sequentially generated by cortical progenitor cells. Faithful progenitor lineage progression requires the tight orchestration of distinct molecular and cellular mechanisms regulating proper progenitor proliferation behavior and differentiation. Correct execution of developmental programs involves a complex interplay of cell intrinsic and tissue-wide mechanisms. Many studies over the past decades have been able to determine a plethora of genes critically involved in cortical development. However, only a few made use of genetic paradigms with sparse and global gene deletion to probe cell-autonomous vs. tissue-wide contribution. In this chapter, we will elaborate on the importance of dissecting the cell-autonomous and tissue-wide mechanisms to gain a precise understanding of gene function during radial glial progenitor lineage progression.","lang":"eng"}],"citation":{"ama":"Villalba Requena A, Amberg N, Hippenmeyer S. Interplay of Cell‐autonomous Gene Function and Tissue‐wide Mechanisms Regulating Radial Glial Progenitor Lineage Progression. In: Huttner W, ed. <i>Neocortical Neurogenesis in Development and Evolution</i>. Wiley; 2023:169-191. doi:<a href=\"https://doi.org/10.1002/9781119860914.ch10\">10.1002/9781119860914.ch10</a>","chicago":"Villalba Requena, Ana, Nicole Amberg, and Simon Hippenmeyer. “Interplay of Cell‐autonomous Gene Function and Tissue‐wide Mechanisms Regulating Radial Glial Progenitor Lineage Progression.” In <i>Neocortical Neurogenesis in Development and Evolution</i>, edited by Wieland Huttner, 169–91. Wiley, 2023. <a href=\"https://doi.org/10.1002/9781119860914.ch10\">https://doi.org/10.1002/9781119860914.ch10</a>.","short":"A. Villalba Requena, N. Amberg, S. Hippenmeyer, in:, W. Huttner (Ed.), Neocortical Neurogenesis in Development and Evolution, Wiley, 2023, pp. 169–191.","mla":"Villalba Requena, Ana, et al. “Interplay of Cell‐autonomous Gene Function and Tissue‐wide Mechanisms Regulating Radial Glial Progenitor Lineage Progression.” <i>Neocortical Neurogenesis in Development and Evolution</i>, edited by Wieland Huttner, Wiley, 2023, pp. 169–91, doi:<a href=\"https://doi.org/10.1002/9781119860914.ch10\">10.1002/9781119860914.ch10</a>.","ista":"Villalba Requena A, Amberg N, Hippenmeyer S. 2023.Interplay of Cell‐autonomous Gene Function and Tissue‐wide Mechanisms Regulating Radial Glial Progenitor Lineage Progression. In: Neocortical Neurogenesis in Development and Evolution. , 169–191.","apa":"Villalba Requena, A., Amberg, N., &#38; Hippenmeyer, S. (2023). Interplay of Cell‐autonomous Gene Function and Tissue‐wide Mechanisms Regulating Radial Glial Progenitor Lineage Progression. In W. Huttner (Ed.), <i>Neocortical Neurogenesis in Development and Evolution</i> (pp. 169–191). Wiley. <a href=\"https://doi.org/10.1002/9781119860914.ch10\">https://doi.org/10.1002/9781119860914.ch10</a>","ieee":"A. Villalba Requena, N. Amberg, and S. Hippenmeyer, “Interplay of Cell‐autonomous Gene Function and Tissue‐wide Mechanisms Regulating Radial Glial Progenitor Lineage Progression,” in <i>Neocortical Neurogenesis in Development and Evolution</i>, W. Huttner, Ed. Wiley, 2023, pp. 169–191."},"article_processing_charge":"No","day":"08","department":[{"_id":"SiHi"}],"date_updated":"2024-10-09T21:07:46Z","title":"Interplay of Cell‐autonomous Gene Function and Tissue‐wide Mechanisms Regulating Radial Glial Progenitor Lineage Progression","oa_version":"None","language":[{"iso":"eng"}],"type":"book_chapter","doi":"10.1002/9781119860914.ch10","status":"public","publication":"Neocortical Neurogenesis in Development and Evolution","date_created":"2024-01-08T13:16:36Z","publication_identifier":{"eisbn":["9781119860914"]},"_id":"14757","author":[{"full_name":"Villalba Requena, Ana","orcid":"0000-0002-5615-5277","last_name":"Villalba Requena","id":"68cb85a0-39f7-11eb-9559-9aaab4f6a247","first_name":"Ana"},{"full_name":"Amberg, Nicole","orcid":"0000-0002-3183-8207","last_name":"Amberg","id":"4CD6AAC6-F248-11E8-B48F-1D18A9856A87","first_name":"Nicole"},{"id":"37B36620-F248-11E8-B48F-1D18A9856A87","first_name":"Simon","orcid":"0000-0003-2279-1061","last_name":"Hippenmeyer","full_name":"Hippenmeyer, Simon"}],"fulldoi":"https://doi.org/10.1002/9781119860914.ch10","corr_author":"1","scopus_import":"1","publisher":"Wiley"},{"conference":{"end_date":"2023-07-22","name":"CAV: Computer Aided Verification","start_date":"2023-07-17","location":"Paris, France"},"type":"conference","file_date_updated":"2024-01-09T10:01:07Z","doi":"10.1007/978-3-031-37709-9_1","status":"public","date_created":"2024-01-08T13:18:00Z","acknowledgement":"Authors ordered alphabetically. R. Majumdar and A.-K. Schmuck are partially supported by DFG project 389792660 TRR 248-CPEC. A.-K. Schmuck is additionally funded through DFG project (SCHM 3541/1-1). K. Mallik is supported by the ERC project ERC-2020-AdG 101020093. M. Rychlicki is supported by the EPSRC project EP/V00252X/1. S. Soudjani is supported by the following projects: EPSRC EP/V043676/1, EIC 101070802, and ERC 101089047.","author":[{"full_name":"Majumdar, Rupak","last_name":"Majumdar","first_name":"Rupak"},{"orcid":"0000-0001-9864-7475","last_name":"Mallik","first_name":"Kaushik","id":"0834ff3c-6d72-11ec-94e0-b5b0a4fb8598","full_name":"Mallik, Kaushik"},{"first_name":"Mateusz","last_name":"Rychlicki","full_name":"Rychlicki, Mateusz"},{"last_name":"Schmuck","first_name":"Anne-Kathrin","full_name":"Schmuck, Anne-Kathrin"},{"full_name":"Soudjani, Sadegh","first_name":"Sadegh","last_name":"Soudjani"}],"ddc":["000"],"corr_author":"1","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"alternative_title":["LNCS"],"isi":1,"page":"3-15","quality_controlled":"1","external_id":{"isi":["001310805600001"]},"year":"2023","intvolume":"     13966","abstract":[{"text":"We present a flexible and efficient toolchain to symbolically solve (standard) Rabin games, fair-adversarial Rabin games, and 2 1/2 license type-player Rabin games. To our best knowledge, our tools are the first ones to be able to solve these problems. Furthermore, using these flexible game solvers as a back-end, we implemented a tool for computing correct-by-construction controllers for stochastic dynamical systems under LTL specifications. Our implementations use the recent theoretical result that all of these games can be solved using the same symbolic fixpoint algorithm but utilizing different, domain specific calculations of the involved predecessor operators. The main feature of our toolchain is the utilization of two programming abstractions: one to separate the symbolic fixpoint computations from the predecessor calculations, and another one to allow the integration of different BDD libraries as back-ends. In particular, we employ a multi-threaded execution of the fixpoint algorithm by using the multi-threaded BDD library Sylvan, which leads to enormous computational savings.","lang":"eng"}],"file":[{"access_level":"open_access","file_name":"2023_LNCSCAV_Majumdar.pdf","date_updated":"2024-01-09T10:01:07Z","creator":"dernst","content_type":"application/pdf","checksum":"1a361d83db0244fd32c03b544c294b5a","success":1,"file_id":"14765","date_created":"2024-01-09T10:01:07Z","file_size":405147,"relation":"main_file"}],"day":"16","title":"A flexible toolchain for symbolic rabin games under fair and stochastic uncertainties","date_updated":"2025-09-09T14:16:49Z","language":[{"iso":"eng"}],"oa_version":"Published Version","oa":1,"has_accepted_license":"1","project":[{"_id":"62781420-2b32-11ec-9570-8d9b63373d4d","call_identifier":"H2020","name":"Vigilant Algorithmic Monitoring of Software","grant_number":"101020093"}],"publication":"35th International Conference on Computer Aided Verification","publication_identifier":{"eisbn":["9783031377099"],"issn":["0302-9743"],"eissn":["1611-3349"],"isbn":["9783031377082"]},"_id":"14758","fulldoi":"https://doi.org/10.1007/978-3-031-37709-9_1","publisher":"Springer Nature","scopus_import":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","related_material":{"record":[{"status":"public","id":"14994","relation":"research_data"}]},"publication_status":"published","date_published":"2023-07-16T00:00:00Z","month":"07","volume":13966,"ec_funded":1,"citation":{"ama":"Majumdar R, Mallik K, Rychlicki M, Schmuck A-K, Soudjani S. A flexible toolchain for symbolic rabin games under fair and stochastic uncertainties. In: <i>35th International Conference on Computer Aided Verification</i>. Vol 13966. Springer Nature; 2023:3-15. doi:<a href=\"https://doi.org/10.1007/978-3-031-37709-9_1\">10.1007/978-3-031-37709-9_1</a>","chicago":"Majumdar, Rupak, Kaushik Mallik, Mateusz Rychlicki, Anne-Kathrin Schmuck, and Sadegh Soudjani. “A Flexible Toolchain for Symbolic Rabin Games under Fair and Stochastic Uncertainties.” In <i>35th International Conference on Computer Aided Verification</i>, 13966:3–15. Springer Nature, 2023. <a href=\"https://doi.org/10.1007/978-3-031-37709-9_1\">https://doi.org/10.1007/978-3-031-37709-9_1</a>.","short":"R. Majumdar, K. Mallik, M. Rychlicki, A.-K. Schmuck, S. Soudjani, in:, 35th International Conference on Computer Aided Verification, Springer Nature, 2023, pp. 3–15.","ista":"Majumdar R, Mallik K, Rychlicki M, Schmuck A-K, Soudjani S. 2023. A flexible toolchain for symbolic rabin games under fair and stochastic uncertainties. 35th International Conference on Computer Aided Verification. CAV: Computer Aided Verification, LNCS, vol. 13966, 3–15.","mla":"Majumdar, Rupak, et al. “A Flexible Toolchain for Symbolic Rabin Games under Fair and Stochastic Uncertainties.” <i>35th International Conference on Computer Aided Verification</i>, vol. 13966, Springer Nature, 2023, pp. 3–15, doi:<a href=\"https://doi.org/10.1007/978-3-031-37709-9_1\">10.1007/978-3-031-37709-9_1</a>.","apa":"Majumdar, R., Mallik, K., Rychlicki, M., Schmuck, A.-K., &#38; Soudjani, S. (2023). A flexible toolchain for symbolic rabin games under fair and stochastic uncertainties. In <i>35th International Conference on Computer Aided Verification</i> (Vol. 13966, pp. 3–15). Paris, France: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-031-37709-9_1\">https://doi.org/10.1007/978-3-031-37709-9_1</a>","ieee":"R. Majumdar, K. Mallik, M. Rychlicki, A.-K. Schmuck, and S. Soudjani, “A flexible toolchain for symbolic rabin games under fair and stochastic uncertainties,” in <i>35th International Conference on Computer Aided Verification</i>, Paris, France, 2023, vol. 13966, pp. 3–15."},"article_processing_charge":"Yes (in subscription journal)","department":[{"_id":"ToHe"}]},{"department":[{"_id":"MoHe"}],"article_processing_charge":"No","citation":{"short":"V. Cohen-Addad, D. Saulpic, C. Schwiegelshohn, in:, 2023 IEEE 64th Annual Symposium on Foundations of Computer Science, IEEE, 2023, pp. 1105–1130.","mla":"Cohen-Addad, Vincent, et al. “Deterministic Clustering in High Dimensional Spaces: Sketches and Approximation.” <i>2023 IEEE 64th Annual Symposium on Foundations of Computer Science</i>, IEEE, 2023, pp. 1105–30, doi:<a href=\"https://doi.org/10.1109/focs57990.2023.00066\">10.1109/focs57990.2023.00066</a>.","ista":"Cohen-Addad V, Saulpic D, Schwiegelshohn C. 2023. Deterministic clustering in high dimensional spaces: Sketches and approximation. 2023 IEEE 64th Annual Symposium on Foundations of Computer Science. FOCS: Foundations of Computer Science, 1105–1130.","apa":"Cohen-Addad, V., Saulpic, D., &#38; Schwiegelshohn, C. (2023). Deterministic clustering in high dimensional spaces: Sketches and approximation. In <i>2023 IEEE 64th Annual Symposium on Foundations of Computer Science</i> (pp. 1105–1130). Santa Cruz, CA, United States: IEEE. <a href=\"https://doi.org/10.1109/focs57990.2023.00066\">https://doi.org/10.1109/focs57990.2023.00066</a>","ieee":"V. Cohen-Addad, D. Saulpic, and C. Schwiegelshohn, “Deterministic clustering in high dimensional spaces: Sketches and approximation,” in <i>2023 IEEE 64th Annual Symposium on Foundations of Computer Science</i>, Santa Cruz, CA, United States, 2023, pp. 1105–1130.","ama":"Cohen-Addad V, Saulpic D, Schwiegelshohn C. Deterministic clustering in high dimensional spaces: Sketches and approximation. In: <i>2023 IEEE 64th Annual Symposium on Foundations of Computer Science</i>. IEEE; 2023:1105-1130. doi:<a href=\"https://doi.org/10.1109/focs57990.2023.00066\">10.1109/focs57990.2023.00066</a>","chicago":"Cohen-Addad, Vincent, David Saulpic, and Chris Schwiegelshohn. “Deterministic Clustering in High Dimensional Spaces: Sketches and Approximation.” In <i>2023 IEEE 64th Annual Symposium on Foundations of Computer Science</i>, 1105–30. IEEE, 2023. <a href=\"https://doi.org/10.1109/focs57990.2023.00066\">https://doi.org/10.1109/focs57990.2023.00066</a>."},"ec_funded":1,"date_published":"2023-12-22T00:00:00Z","publication_status":"published","month":"12","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","fulldoi":"https://doi.org/10.1109/focs57990.2023.00066","publisher":"IEEE","scopus_import":"1","publication":"2023 IEEE 64th Annual Symposium on Foundations of Computer Science","_id":"14768","publication_identifier":{"eisbn":["9798350318944"]},"project":[{"call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"},{"grant_number":"101019564","name":"The design and evaluation of modern fully dynamic data structures","call_identifier":"H2020","_id":"bd9ca328-d553-11ed-ba76-dc4f890cfe62"}],"arxiv":1,"oa":1,"date_updated":"2025-09-09T14:17:59Z","title":"Deterministic clustering in high dimensional spaces: Sketches and approximation","day":"22","language":[{"iso":"eng"}],"oa_version":"Preprint","abstract":[{"text":"In all state-of-the-art sketching and coreset techniques for clustering, as well as in the best known fixed-parameter tractable approximation algorithms, randomness plays a key role. For the classic k-median and k-means problems, there are no known deterministic dimensionality reduction procedure or coreset construction that avoid an exponential dependency on the input dimension d, the precision parameter $\\varepsilon^{-1}$ or k. Furthermore, there is no coreset construction that succeeds with probability $1-1/n$ and whose size does not depend on the number of input points, n. This has led researchers in the area to ask what is the power of randomness for clustering sketches [Feldman WIREs Data Mining Knowl. Discov’20].Similarly, the best approximation ratio achievable deterministically without a complexity exponential in the dimension are $1+\\sqrt{2}$ for k-median [Cohen-Addad, Esfandiari, Mirrokni, Narayanan, STOC’22] and 6.12903 for k-means [Grandoni, Ostrovsky, Rabani, Schulman, Venkat, Inf. Process. Lett.’22]. Those are the best results, even when allowing a complexity FPT in the number of clusters k: this stands in sharp contrast with the $(1+\\varepsilon)$-approximation achievable in that case, when allowing randomization.In this paper, we provide deterministic sketches constructions for clustering, whose size bounds are close to the best-known randomized ones. We show how to compute a dimension reduction onto $\\varepsilon^{-O(1)} \\log k$ dimensions in time $k^{O\\left(\\varepsilon^{-O(1)}+\\log \\log k\\right)}$ poly $(n d)$, and how to build a coreset of size $O\\left(k^{2} \\log ^{3} k \\varepsilon^{-O(1)}\\right)$ in time $2^{\\varepsilon^{O(1)} k \\log ^{3} k}+k^{O\\left(\\varepsilon^{-O(1)}+\\log \\log k\\right)}$ poly $(n d)$. In the case where k is small, this answers an open question of [Feldman WIDM’20] and [Munteanu and Schwiegelshohn, Künstliche Intell. ’18] on whether it is possible to efficiently compute coresets deterministically.We also construct a deterministic algorithm for computing $(1+$ $\\varepsilon)$-approximation to k-median and k-means in high dimensional Euclidean spaces in time $2^{k^{2} \\log ^{3} k / \\varepsilon^{O(1)}}$ poly $(n d)$, close to the best randomized complexity of $2^{(k / \\varepsilon)^{O(1)}}$ nd (see [Kumar, Sabharwal, Sen, JACM 10] and [Bhattacharya, Jaiswal, Kumar, TCS’18]).Furthermore, our new insights on sketches also yield a randomized coreset construction that uses uniform sampling, that immediately improves over the recent results of [Braverman et al. FOCS ’22] by a factor k.","lang":"eng"}],"external_id":{"arxiv":["2310.04076"],"isi":["001137125900060"]},"year":"2023","page":"1105-1130","isi":1,"quality_controlled":"1","author":[{"last_name":"Cohen-Addad","first_name":"Vincent","full_name":"Cohen-Addad, Vincent"},{"full_name":"Saulpic, David","last_name":"Saulpic","first_name":"David","id":"f8e48cf0-b0ff-11ed-b0e9-b4c35598f964"},{"full_name":"Schwiegelshohn, Chris","last_name":"Schwiegelshohn","first_name":"Chris"}],"date_created":"2024-01-09T16:20:09Z","acknowledgement":"D. Sauplic has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034413, and Grant agreement No. 101019564 “The Design of Modern Fully Dynamic Data Structures (MoDynStruct)”.\r\nC. Schwiegelshohn acknowledges the support of the Independent Research Fund Denmark (DFF) under a Sapere Aude Research Leader grant No 1051-00106B.","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2310.04076","open_access":"1"}],"type":"conference","doi":"10.1109/focs57990.2023.00066","status":"public","conference":{"start_date":"2023-11-06","name":"FOCS: Foundations of Computer Science","location":"Santa Cruz, CA, United States","end_date":"2023-11-09"}},{"date_created":"2024-01-10T08:07:15Z","issue":"8","author":[{"full_name":"Danzl, Johann G","id":"42EFD3B6-F248-11E8-B48F-1D18A9856A87","first_name":"Johann G","orcid":"0000-0001-8559-3973","last_name":"Danzl"},{"full_name":"Velicky, Philipp","orcid":"0000-0002-2340-7431","last_name":"Velicky","first_name":"Philipp","id":"39BDC62C-F248-11E8-B48F-1D18A9856A87"}],"corr_author":"1","type":"journal_article","doi":"10.1038/s41592-023-01937-5","status":"public","intvolume":"        20","abstract":[{"lang":"eng","text":"We developed LIONESS, a technology that leverages improvements to optical super-resolution microscopy and prior information on sample structure via machine learning to overcome the limitations (in 3D-resolution, signal-to-noise ratio and light exposure) of optical microscopy of living biological specimens. LIONESS enables dense reconstruction of living brain tissue and morphodynamics visualization at the nanoscale."}],"day":"01","date_updated":"2026-04-14T08:34:34Z","title":"LIONESS enables 4D nanoscale reconstruction of living brain tissue","language":[{"iso":"eng"}],"oa_version":"None","isi":1,"keyword":["Cell Biology","Molecular Biology","Biochemistry","Biotechnology"],"page":"1141-1142","quality_controlled":"1","external_id":{"isi":["001025621500002"]},"year":"2023","publication":"Nature Methods","_id":"14770","publication_identifier":{"issn":["1548-7091"],"eissn":["1548-7105"]},"fulldoi":"https://doi.org/10.1038/s41592-023-01937-5","scopus_import":"1","publisher":"Springer Nature","volume":20,"citation":{"short":"J.G. Danzl, P. Velicky, Nature Methods 20 (2023) 1141–1142.","mla":"Danzl, Johann G., and Philipp Velicky. “LIONESS Enables 4D Nanoscale Reconstruction of Living Brain Tissue.” <i>Nature Methods</i>, vol. 20, no. 8, Springer Nature, 2023, pp. 1141–42, doi:<a href=\"https://doi.org/10.1038/s41592-023-01937-5\">10.1038/s41592-023-01937-5</a>.","ista":"Danzl JG, Velicky P. 2023. LIONESS enables 4D nanoscale reconstruction of living brain tissue. Nature Methods. 20(8), 1141–1142.","apa":"Danzl, J. G., &#38; Velicky, P. (2023). LIONESS enables 4D nanoscale reconstruction of living brain tissue. <i>Nature Methods</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41592-023-01937-5\">https://doi.org/10.1038/s41592-023-01937-5</a>","ieee":"J. G. Danzl and P. Velicky, “LIONESS enables 4D nanoscale reconstruction of living brain tissue,” <i>Nature Methods</i>, vol. 20, no. 8. Springer Nature, pp. 1141–1142, 2023.","ama":"Danzl JG, Velicky P. LIONESS enables 4D nanoscale reconstruction of living brain tissue. <i>Nature Methods</i>. 2023;20(8):1141-1142. doi:<a href=\"https://doi.org/10.1038/s41592-023-01937-5\">10.1038/s41592-023-01937-5</a>","chicago":"Danzl, Johann G, and Philipp Velicky. “LIONESS Enables 4D Nanoscale Reconstruction of Living Brain Tissue.” <i>Nature Methods</i>. Springer Nature, 2023. <a href=\"https://doi.org/10.1038/s41592-023-01937-5\">https://doi.org/10.1038/s41592-023-01937-5</a>."},"department":[{"_id":"JoDa"}],"article_processing_charge":"No","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_type":"letter_note","related_material":{"record":[{"id":"13267","status":"public","relation":"extended_version"}]},"date_published":"2023-08-01T00:00:00Z","publication_status":"published","month":"08"},{"oa":1,"has_accepted_license":"1","arxiv":1,"publication":"Journal of Functional Analysis","publication_identifier":{"issn":["0022-1236"]},"_id":"14772","fulldoi":"https://doi.org/10.1016/j.jfa.2023.110146","scopus_import":"1","publisher":"Elsevier","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_type":"original","publication_status":"published","date_published":"2023-12-01T00:00:00Z","month":"12","volume":285,"citation":{"ieee":"A. Agresti and A. Hussein, “Maximal Lp-regularity and H∞-calculus for block operator matrices and applications,” <i>Journal of Functional Analysis</i>, vol. 285, no. 11. Elsevier, 2023.","ista":"Agresti A, Hussein A. 2023. Maximal Lp-regularity and H∞-calculus for block operator matrices and applications. Journal of Functional Analysis. 285(11), 110146.","mla":"Agresti, Antonio, and Amru Hussein. “Maximal Lp-Regularity and H∞-Calculus for Block Operator Matrices and Applications.” <i>Journal of Functional Analysis</i>, vol. 285, no. 11, 110146, Elsevier, 2023, doi:<a href=\"https://doi.org/10.1016/j.jfa.2023.110146\">10.1016/j.jfa.2023.110146</a>.","apa":"Agresti, A., &#38; Hussein, A. (2023). Maximal Lp-regularity and H∞-calculus for block operator matrices and applications. <i>Journal of Functional Analysis</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jfa.2023.110146\">https://doi.org/10.1016/j.jfa.2023.110146</a>","short":"A. Agresti, A. Hussein, Journal of Functional Analysis 285 (2023).","chicago":"Agresti, Antonio, and Amru Hussein. “Maximal Lp-Regularity and H∞-Calculus for Block Operator Matrices and Applications.” <i>Journal of Functional Analysis</i>. Elsevier, 2023. <a href=\"https://doi.org/10.1016/j.jfa.2023.110146\">https://doi.org/10.1016/j.jfa.2023.110146</a>.","ama":"Agresti A, Hussein A. Maximal Lp-regularity and H∞-calculus for block operator matrices and applications. <i>Journal of Functional Analysis</i>. 2023;285(11). doi:<a href=\"https://doi.org/10.1016/j.jfa.2023.110146\">10.1016/j.jfa.2023.110146</a>"},"article_processing_charge":"Yes (via OA deal)","department":[{"_id":"JuFi"}],"type":"journal_article","file_date_updated":"2024-01-10T11:23:57Z","status":"public","doi":"10.1016/j.jfa.2023.110146","date_created":"2024-01-10T09:15:18Z","acknowledgement":"We would like to thank Tim Binz, Emiel Lorist and Mark Veraar for valuable discussions. We also thank the anonymous referees for their helpful comments and suggestions, and for the very accurate reading of the manuscript.\r\nThe first author has been supported partially by the Nachwuchsring – Network for the promotion of young scientists – at TU Kaiserslautern. Both authors have been supported by MathApp – Mathematics Applied to Real-World Problems - part of the Research Initiative of the Federal State of Rhineland-Palatinate, Germany.","issue":"11","author":[{"full_name":"Agresti, Antonio","id":"673cd0cc-9b9a-11eb-b144-88f30e1fbb72","first_name":"Antonio","orcid":"0000-0002-9573-2962","last_name":"Agresti"},{"full_name":"Hussein, Amru","last_name":"Hussein","first_name":"Amru"}],"ddc":["510"],"corr_author":"1","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"isi":1,"keyword":["Analysis"],"quality_controlled":"1","external_id":{"arxiv":["2108.01962"],"isi":["001081809000001"]},"year":"2023","intvolume":"       285","article_number":"110146","abstract":[{"lang":"eng","text":"Many coupled evolution equations can be described via 2×2-block operator matrices of the form A=[ \r\nA\tB\r\nC\tD\r\n ] in a product space X=X1×X2 with possibly unbounded entries. Here, the case of diagonally dominant block operator matrices is considered, that is, the case where the full operator A can be seen as a relatively bounded perturbation of its diagonal part with D(A)=D(A)×D(D) though with possibly large relative bound. For such operators the properties of sectoriality, R-sectoriality and the boundedness of the H∞-calculus are studied, and for these properties perturbation results for possibly large but structured perturbations are derived. Thereby, the time dependent parabolic problem associated with A can be analyzed in maximal Lpt\r\n-regularity spaces, and this is applied to a wide range of problems such as different theories for liquid crystals, an artificial Stokes system, strongly damped wave and plate equations, and a Keller-Segel model."}],"file":[{"success":1,"checksum":"eda98ca2aa73da91bd074baed34c2b3c","content_type":"application/pdf","creator":"dernst","file_id":"14789","date_created":"2024-01-10T11:23:57Z","access_level":"open_access","date_updated":"2024-01-10T11:23:57Z","file_name":"2023_JourFunctionalAnalysis_Agresti.pdf","relation":"main_file","file_size":1120592}],"day":"01","title":"Maximal Lp-regularity and H∞-calculus for block operator matrices and applications","date_updated":"2024-10-09T21:07:48Z","language":[{"iso":"eng"}],"oa_version":"Published Version"},{"oa":1,"publication":"Physics Today","_id":"14773","publication_identifier":{"eissn":["1945-0699"],"issn":["0031-9228"]},"fulldoi":"https://doi.org/10.1063/pt.3.5234","publisher":"AIP Publishing","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_type":"original","publication_status":"published","date_published":"2023-05-01T00:00:00Z","month":"05","volume":76,"citation":{"short":"C.J. Muller, S. Abramian, Physics Today 76 (2023).","apa":"Muller, C. J., &#38; Abramian, S. (2023). The cloud dynamics of convective storm systems. <i>Physics Today</i>. AIP Publishing. <a href=\"https://doi.org/10.1063/pt.3.5234\">https://doi.org/10.1063/pt.3.5234</a>","ista":"Muller CJ, Abramian S. 2023. The cloud dynamics of convective storm systems. Physics Today. 76(5), 28.","mla":"Muller, Caroline J., and Sophie Abramian. “The Cloud Dynamics of Convective Storm Systems.” <i>Physics Today</i>, vol. 76, no. 5, 28, AIP Publishing, 2023, doi:<a href=\"https://doi.org/10.1063/pt.3.5234\">10.1063/pt.3.5234</a>.","ieee":"C. J. Muller and S. Abramian, “The cloud dynamics of convective storm systems,” <i>Physics Today</i>, vol. 76, no. 5. AIP Publishing, 2023.","ama":"Muller CJ, Abramian S. The cloud dynamics of convective storm systems. <i>Physics Today</i>. 2023;76(5). doi:<a href=\"https://doi.org/10.1063/pt.3.5234\">10.1063/pt.3.5234</a>","chicago":"Muller, Caroline J, and Sophie Abramian. “The Cloud Dynamics of Convective Storm Systems.” <i>Physics Today</i>. AIP Publishing, 2023. <a href=\"https://doi.org/10.1063/pt.3.5234\">https://doi.org/10.1063/pt.3.5234</a>."},"article_processing_charge":"No","department":[{"_id":"CaMu"}],"type":"journal_article","doi":"10.1063/pt.3.5234","status":"public","date_created":"2024-01-10T09:18:04Z","issue":"5","main_file_link":[{"open_access":"1","url":"https://www.lmd.ens.fr/muller/Pubs/2023-MullerAbramianPhysToday.pdf"}],"ddc":["550"],"author":[{"id":"f978ccb0-3f7f-11eb-b193-b0e2bd13182b","first_name":"Caroline J","last_name":"Muller","orcid":"0000-0001-5836-5350","full_name":"Muller, Caroline J"},{"full_name":"Abramian, Sophie","last_name":"Abramian","first_name":"Sophie"}],"corr_author":"1","keyword":["General Physics and Astronomy"],"isi":1,"quality_controlled":"1","external_id":{"isi":["000984516100007"]},"year":"2023","intvolume":"        76","article_number":"28","abstract":[{"text":"Through a combination of idealized simulations and real-world data, researchers are uncovering how internal feedbacks and large-scale motions influence cloud dynamics.","lang":"eng"}],"title":"The cloud dynamics of convective storm systems","date_updated":"2026-06-18T17:38:37Z","day":"01","oa_version":"Published Version","language":[{"iso":"eng"}]},{"department":[{"_id":"LaEr"}],"article_processing_charge":"No","citation":{"ieee":"K. Schnelli and Y. Xu, “Convergence rate to the Tracy–Widom laws for the largest eigenvalue of sample covariance matrices,” <i>The Annals of Applied Probability</i>, vol. 33, no. 1. Institute of Mathematical Statistics, pp. 677–725, 2023.","apa":"Schnelli, K., &#38; Xu, Y. (2023). Convergence rate to the Tracy–Widom laws for the largest eigenvalue of sample covariance matrices. <i>The Annals of Applied Probability</i>. Institute of Mathematical Statistics. <a href=\"https://doi.org/10.1214/22-aap1826\">https://doi.org/10.1214/22-aap1826</a>","ista":"Schnelli K, Xu Y. 2023. Convergence rate to the Tracy–Widom laws for the largest eigenvalue of sample covariance matrices. The Annals of Applied Probability. 33(1), 677–725.","mla":"Schnelli, Kevin, and Yuanyuan Xu. “Convergence Rate to the Tracy–Widom Laws for the Largest Eigenvalue of Sample Covariance Matrices.” <i>The Annals of Applied Probability</i>, vol. 33, no. 1, Institute of Mathematical Statistics, 2023, pp. 677–725, doi:<a href=\"https://doi.org/10.1214/22-aap1826\">10.1214/22-aap1826</a>.","short":"K. Schnelli, Y. Xu, The Annals of Applied Probability 33 (2023) 677–725.","chicago":"Schnelli, Kevin, and Yuanyuan Xu. “Convergence Rate to the Tracy–Widom Laws for the Largest Eigenvalue of Sample Covariance Matrices.” <i>The Annals of Applied Probability</i>. Institute of Mathematical Statistics, 2023. <a href=\"https://doi.org/10.1214/22-aap1826\">https://doi.org/10.1214/22-aap1826</a>.","ama":"Schnelli K, Xu Y. Convergence rate to the Tracy–Widom laws for the largest eigenvalue of sample covariance matrices. <i>The Annals of Applied Probability</i>. 2023;33(1):677-725. doi:<a href=\"https://doi.org/10.1214/22-aap1826\">10.1214/22-aap1826</a>"},"ec_funded":1,"volume":33,"month":"02","date_published":"2023-02-01T00:00:00Z","publication_status":"published","article_type":"original","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"Institute of Mathematical Statistics","scopus_import":"1","fulldoi":"https://doi.org/10.1214/22-aap1826","_id":"14775","publication_identifier":{"issn":["1050-5164"]},"publication":"The Annals of Applied Probability","arxiv":1,"project":[{"grant_number":"101020331","name":"Random matrices beyond Wigner-Dyson-Mehta","call_identifier":"H2020","_id":"62796744-2b32-11ec-9570-940b20777f1d"}],"oa":1,"language":[{"iso":"eng"}],"oa_version":"Preprint","date_updated":"2025-04-14T07:57:19Z","title":"Convergence rate to the Tracy–Widom laws for the largest eigenvalue of sample covariance matrices","day":"01","abstract":[{"lang":"eng","text":"We establish a quantitative version of the Tracy–Widom law for the largest eigenvalue of high-dimensional sample covariance matrices. To be precise, we show that the fluctuations of the largest eigenvalue of a sample covariance matrix X∗X converge to its Tracy–Widom limit at a rate nearly N−1/3, where X is an M×N random matrix whose entries are independent real or complex random variables, assuming that both M and N tend to infinity at a constant rate. This result improves the previous estimate N−2/9 obtained by Wang (2019). Our proof relies on a Green function comparison method (Adv. Math. 229 (2012) 1435–1515) using iterative cumulant expansions, the local laws for the Green function and asymptotic properties of the correlation kernel of the white Wishart ensemble."}],"intvolume":"        33","year":"2023","external_id":{"isi":["000946432400021"],"arxiv":["2108.02728"]},"quality_controlled":"1","page":"677-725","keyword":["Statistics","Probability and Uncertainty","Statistics and Probability"],"isi":1,"corr_author":"1","author":[{"full_name":"Schnelli, Kevin","last_name":"Schnelli","orcid":"0000-0003-0954-3231","first_name":"Kevin","id":"434AD0AE-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Xu","orcid":"0000-0003-1559-1205","first_name":"Yuanyuan","id":"7902bdb1-a2a4-11eb-a164-c9216f71aea3","full_name":"Xu, Yuanyuan"}],"issue":"1","acknowledgement":"K. Schnelli was supported by the Swedish Research Council Grants VR-2017-05195, and the Knut and Alice Wallenberg Foundation. Y. Xu was supported by the Swedish Research Council Grant VR-2017-05195 and the ERC Advanced Grant “RMTBeyond” No. 101020331.","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2108.02728","open_access":"1"}],"date_created":"2024-01-10T09:23:31Z","status":"public","doi":"10.1214/22-aap1826","type":"journal_article"},{"date_published":"2023-11-01T00:00:00Z","publication_status":"published","month":"11","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_type":"original","article_processing_charge":"Yes","department":[{"_id":"JiFr"}],"volume":24,"citation":{"chicago":"Teplova, Anastasiia, Artemii A. Pigidanov, Marina V. Serebryakova, Sergei A. Golyshev, Raisa A. Galiullina, Nina V. Chichkova, and Andrey B. Vartapetian. “Phytaspase Is Capable of Detaching the Endoplasmic Reticulum Retrieval Signal from Tobacco Calreticulin-3.” <i>International Journal of Molecular Sciences</i>. MDPI, 2023. <a href=\"https://doi.org/10.3390/ijms242216527\">https://doi.org/10.3390/ijms242216527</a>.","ama":"Teplova A, Pigidanov AA, Serebryakova MV, et al. Phytaspase Is capable of detaching the endoplasmic reticulum retrieval signal from tobacco calreticulin-3. <i>International Journal of Molecular Sciences</i>. 2023;24(22). doi:<a href=\"https://doi.org/10.3390/ijms242216527\">10.3390/ijms242216527</a>","short":"A. Teplova, A.A. Pigidanov, M.V. Serebryakova, S.A. Golyshev, R.A. Galiullina, N.V. Chichkova, A.B. Vartapetian, International Journal of Molecular Sciences 24 (2023).","apa":"Teplova, A., Pigidanov, A. A., Serebryakova, M. V., Golyshev, S. A., Galiullina, R. A., Chichkova, N. V., &#38; Vartapetian, A. B. (2023). Phytaspase Is capable of detaching the endoplasmic reticulum retrieval signal from tobacco calreticulin-3. <i>International Journal of Molecular Sciences</i>. MDPI. <a href=\"https://doi.org/10.3390/ijms242216527\">https://doi.org/10.3390/ijms242216527</a>","ista":"Teplova A, Pigidanov AA, Serebryakova MV, Golyshev SA, Galiullina RA, Chichkova NV, Vartapetian AB. 2023. Phytaspase Is capable of detaching the endoplasmic reticulum retrieval signal from tobacco calreticulin-3. International Journal of Molecular Sciences. 24(22), 16527.","mla":"Teplova, Anastasiia, et al. “Phytaspase Is Capable of Detaching the Endoplasmic Reticulum Retrieval Signal from Tobacco Calreticulin-3.” <i>International Journal of Molecular Sciences</i>, vol. 24, no. 22, 16527, MDPI, 2023, doi:<a href=\"https://doi.org/10.3390/ijms242216527\">10.3390/ijms242216527</a>.","ieee":"A. Teplova <i>et al.</i>, “Phytaspase Is capable of detaching the endoplasmic reticulum retrieval signal from tobacco calreticulin-3,” <i>International Journal of Molecular Sciences</i>, vol. 24, no. 22. MDPI, 2023."},"oa":1,"has_accepted_license":"1","fulldoi":"https://doi.org/10.3390/ijms242216527","publisher":"MDPI","publication":"International Journal of Molecular Sciences","pmid":1,"_id":"14776","publication_identifier":{"issn":["1422-0067"]},"external_id":{"isi":["001113792600001"],"pmid":["38003717"]},"year":"2023","isi":1,"keyword":["Inorganic Chemistry","Organic Chemistry","Physical and Theoretical Chemistry","Computer Science Applications","Spectroscopy","Molecular Biology","General Medicine","Catalysis"],"quality_controlled":"1","day":"01","title":"Phytaspase Is capable of detaching the endoplasmic reticulum retrieval signal from tobacco calreticulin-3","date_updated":"2024-10-09T21:07:49Z","language":[{"iso":"eng"}],"oa_version":"Published Version","intvolume":"        24","abstract":[{"text":"Soluble chaperones residing in the endoplasmic reticulum (ER) play vitally important roles in folding and quality control of newly synthesized proteins that transiently pass through the ER en route to their final destinations. These soluble residents of the ER are themselves endowed with an ER retrieval signal that enables the cell to bring the escaped residents back from the Golgi. Here, by using purified proteins, we showed that Nicotiana tabacum phytaspase, a plant aspartate-specific protease, introduces two breaks at the C-terminus of the N. tabacum ER resident calreticulin-3. These cleavages resulted in removal of either a dipeptide or a hexapeptide from the C-terminus of calreticulin-3 encompassing part or all of the ER retrieval signal. Consistently, expression of the calreticulin-3 derivative mimicking the phytaspase cleavage product in Nicotiana benthamiana cells demonstrated loss of the ER accumulation of the protein. Notably, upon its escape from the ER, calreticulin-3 was further processed by an unknown protease(s) to generate the free N-terminal (N) domain of calreticulin-3, which was ultimately secreted into the apoplast. Our study thus identified a specific proteolytic enzyme capable of precise detachment of the ER retrieval signal from a plant ER resident protein, with implications for the further fate of the escaped resident.","lang":"eng"}],"article_number":"16527","file":[{"date_updated":"2024-01-10T13:39:42Z","file_name":"2023_IJMS_Teplova.pdf","access_level":"open_access","date_created":"2024-01-10T13:39:42Z","file_id":"14791","checksum":"4df7d206ba022b7f54eff1f0aec1659a","success":1,"creator":"dernst","content_type":"application/pdf","file_size":2637784,"relation":"main_file"}],"type":"journal_article","doi":"10.3390/ijms242216527","file_date_updated":"2024-01-10T13:39:42Z","status":"public","author":[{"last_name":"Teplova","id":"e3736151-106c-11ec-b916-c2558e2762c6","first_name":"Anastasiia","full_name":"Teplova, Anastasiia"},{"first_name":"Artemii A.","last_name":"Pigidanov","full_name":"Pigidanov, Artemii A."},{"full_name":"Serebryakova, Marina V.","first_name":"Marina V.","last_name":"Serebryakova"},{"full_name":"Golyshev, Sergei A.","last_name":"Golyshev","first_name":"Sergei A."},{"last_name":"Galiullina","first_name":"Raisa A.","full_name":"Galiullina, Raisa A."},{"first_name":"Nina V.","last_name":"Chichkova","full_name":"Chichkova, Nina V."},{"full_name":"Vartapetian, Andrey B.","last_name":"Vartapetian","first_name":"Andrey B."}],"ddc":["580"],"corr_author":"1","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"date_created":"2024-01-10T09:24:35Z","issue":"22","acknowledgement":"We thank C.U.T. Hellen for critically reading the manuscript. The MALDI MS facility and CLSM became available to us in the framework of Moscow State University Development Programs PNG 5.13 and PNR 5.13.\r\nThis work was funded by the Russian Science Foundation, grant numbers 19-14-00010 and 22-14-00071."},{"type":"journal_article","status":"public","doi":"10.1063/5.0171888","file_date_updated":"2024-01-10T13:47:31Z","ddc":["540"],"author":[{"full_name":"Sato, Kosuke","last_name":"Sato","first_name":"Kosuke"},{"full_name":"Singh, Saurabh","first_name":"Saurabh","id":"12d625da-9cb3-11ed-9667-af09d37d3f0a","last_name":"Singh","orcid":"0000-0003-2209-5269"},{"last_name":"Yamazaki","first_name":"Itsuki","full_name":"Yamazaki, Itsuki"},{"full_name":"Hirata, Keisuke","last_name":"Hirata","first_name":"Keisuke"},{"full_name":"Ang, Artoni Kevin R.","first_name":"Artoni Kevin R.","last_name":"Ang"},{"full_name":"Matsunami, Masaharu","last_name":"Matsunami","first_name":"Masaharu"},{"full_name":"Takeuchi, Tsunehiro","last_name":"Takeuchi","first_name":"Tsunehiro"}],"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"corr_author":"1","date_created":"2024-01-10T09:26:08Z","issue":"12","acknowledgement":"This work received financial support partially from Japan Science and Technology Agency (JST) CREST Grant No. JPMJCR18I2, Japan. The powder-XRD experiments were conducted at BL5S2 of Aichi Synchrotron Radiation Center, Aichi Science & Technology Foundation, Aichi, Japan (Proposal No. 202301057).","external_id":{"isi":["001114917200005"]},"year":"2023","keyword":["General Physics and Astronomy"],"isi":1,"quality_controlled":"1","date_updated":"2024-10-09T21:07:49Z","title":"Improvement of thermoelectric performance of flexible compound Ag2S0.55Se0.45 by means of partial V-substitution for Ag","day":"01","language":[{"iso":"eng"}],"oa_version":"Published Version","intvolume":"        13","file":[{"success":1,"content_type":"application/pdf","creator":"dernst","checksum":"a7098388b8ff822b47f5ddd37ed3bdbc","file_id":"14792","date_created":"2024-01-10T13:47:31Z","access_level":"open_access","file_name":"2023_AIPAdvances_Sato.pdf","date_updated":"2024-01-10T13:47:31Z","relation":"main_file","file_size":9676071}],"article_number":"125206","abstract":[{"text":"The effects of the partial V-substitution for Ag on the thermoelectric (TE) properties are investigated for a flexible semiconducting compound Ag2S0.55Se0.45. Density functional theory calculations predict that such a partial V-substitution constructively modifies the electronic structure near the bottom of the conduction band to improve the TE performance. The synthesized Ag1.97V0.03S0.55Se0.45 is found to possess a TE dimensionless figure-of-merit (ZT) of 0.71 at 350 K with maintaining its flexible nature. This ZT value is relatively high in comparison with those reported for flexible TE materials below 360 K. The increase in the ZT value is caused by the enhanced absolute value of the Seebeck coefficient with less significant variation in electrical resistivity. The high ZT value with the flexible nature naturally allows us to employ the Ag1.97V0.03S0.55Se0.45 as a component of flexible TE generators.","lang":"eng"}],"oa":1,"has_accepted_license":"1","fulldoi":"https://doi.org/10.1063/5.0171888","publisher":"AIP Publishing","publication":"AIP Advances","_id":"14777","publication_identifier":{"eissn":["2158-3226"]},"date_published":"2023-12-01T00:00:00Z","publication_status":"published","month":"12","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_type":"original","department":[{"_id":"MaIb"}],"article_processing_charge":"Yes","volume":13,"citation":{"ieee":"K. Sato <i>et al.</i>, “Improvement of thermoelectric performance of flexible compound Ag2S0.55Se0.45 by means of partial V-substitution for Ag,” <i>AIP Advances</i>, vol. 13, no. 12. AIP Publishing, 2023.","short":"K. Sato, S. Singh, I. Yamazaki, K. Hirata, A.K.R. Ang, M. Matsunami, T. Takeuchi, AIP Advances 13 (2023).","ista":"Sato K, Singh S, Yamazaki I, Hirata K, Ang AKR, Matsunami M, Takeuchi T. 2023. Improvement of thermoelectric performance of flexible compound Ag2S0.55Se0.45 by means of partial V-substitution for Ag. AIP Advances. 13(12), 125206.","apa":"Sato, K., Singh, S., Yamazaki, I., Hirata, K., Ang, A. K. R., Matsunami, M., &#38; Takeuchi, T. (2023). Improvement of thermoelectric performance of flexible compound Ag2S0.55Se0.45 by means of partial V-substitution for Ag. <i>AIP Advances</i>. AIP Publishing. <a href=\"https://doi.org/10.1063/5.0171888\">https://doi.org/10.1063/5.0171888</a>","mla":"Sato, Kosuke, et al. “Improvement of Thermoelectric Performance of Flexible Compound Ag2S0.55Se0.45 by Means of Partial V-Substitution for Ag.” <i>AIP Advances</i>, vol. 13, no. 12, 125206, AIP Publishing, 2023, doi:<a href=\"https://doi.org/10.1063/5.0171888\">10.1063/5.0171888</a>.","ama":"Sato K, Singh S, Yamazaki I, et al. Improvement of thermoelectric performance of flexible compound Ag2S0.55Se0.45 by means of partial V-substitution for Ag. <i>AIP Advances</i>. 2023;13(12). doi:<a href=\"https://doi.org/10.1063/5.0171888\">10.1063/5.0171888</a>","chicago":"Sato, Kosuke, Saurabh Singh, Itsuki Yamazaki, Keisuke Hirata, Artoni Kevin R. Ang, Masaharu Matsunami, and Tsunehiro Takeuchi. “Improvement of Thermoelectric Performance of Flexible Compound Ag2S0.55Se0.45 by Means of Partial V-Substitution for Ag.” <i>AIP Advances</i>. AIP Publishing, 2023. <a href=\"https://doi.org/10.1063/5.0171888\">https://doi.org/10.1063/5.0171888</a>."}},{"status":"public","doi":"10.1145/3585391","file_date_updated":"2024-01-16T08:11:24Z","type":"journal_article","acknowledgement":"This research was partially supported by the ERC CoG (grant no. 863818; ForM-SMArt), the Czech Science Foundation (grant no. GA21-24711S), and the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie Grant Agreement No. 665385.","issue":"2","date_created":"2024-01-10T09:27:43Z","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"corr_author":"1","ddc":["000"],"author":[{"full_name":"Chatterjee, Krishnendu","first_name":"Krishnendu","id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","last_name":"Chatterjee","orcid":"0000-0002-4561-241X"},{"first_name":"Ehsan","last_name":"Kafshdar Goharshady","full_name":"Kafshdar Goharshady, Ehsan"},{"full_name":"Novotný, Petr","last_name":"Novotný","first_name":"Petr","id":"3CC3B868-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Zárevúcky, Jiří","last_name":"Zárevúcky","first_name":"Jiří"},{"first_name":"Dorde","id":"294AA7A6-F248-11E8-B48F-1D18A9856A87","last_name":"Zikelic","orcid":"0000-0002-4681-1699","full_name":"Zikelic, Dorde"}],"quality_controlled":"1","keyword":["Theoretical Computer Science","Software"],"isi":1,"year":"2023","external_id":{"arxiv":["2108.02188"],"isi":["001035915800006"]},"file":[{"file_size":502522,"relation":"main_file","access_level":"open_access","file_name":"2023_FormalAspectsComputing_Chatterjee.pdf","date_updated":"2024-01-16T08:11:24Z","date_created":"2024-01-16T08:11:24Z","content_type":"application/pdf","checksum":"3bb133eeb27ec01649a9a36445d952d9","creator":"dernst","success":1,"file_id":"14804"}],"article_number":"11","abstract":[{"text":"We consider the almost-sure (a.s.) termination problem for probabilistic programs, which are a stochastic extension of classical imperative programs. Lexicographic ranking functions provide a sound and practical approach for termination of non-probabilistic programs, and their extension to probabilistic programs is achieved via lexicographic ranking supermartingales (LexRSMs). However, LexRSMs introduced in the previous work have a limitation that impedes their automation: all of their components have to be non-negative in all reachable states. This might result in a LexRSM not existing even for simple terminating programs. Our contributions are twofold. First, we introduce a generalization of LexRSMs that allows for some components to be negative. This standard feature of non-probabilistic termination proofs was hitherto not known to be sound in the probabilistic setting, as the soundness proof requires a careful analysis of the underlying stochastic process. Second, we present polynomial-time algorithms using our generalized LexRSMs for proving a.s. termination in broad classes of linear-arithmetic programs.","lang":"eng"}],"intvolume":"        35","oa_version":"Published Version","language":[{"iso":"eng"}],"date_updated":"2025-09-09T14:19:27Z","title":"On lexicographic proof rules for probabilistic termination","day":"23","has_accepted_license":"1","oa":1,"arxiv":1,"project":[{"call_identifier":"H2020","name":"Formal Methods for Stochastic Models: Algorithms and Applications","grant_number":"863818","_id":"0599E47C-7A3F-11EA-A408-12923DDC885E"},{"call_identifier":"H2020","grant_number":"665385","name":"International IST Doctoral Program","_id":"2564DBCA-B435-11E9-9278-68D0E5697425"}],"publication_identifier":{"issn":["0934-5043"],"eissn":["1433-299X"]},"_id":"14778","publication":"Formal Aspects of Computing","scopus_import":"1","publisher":"Association for Computing Machinery","fulldoi":"https://doi.org/10.1145/3585391","related_material":{"record":[{"id":"10414","status":"public","relation":"earlier_version"}]},"article_type":"original","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","month":"06","date_published":"2023-06-23T00:00:00Z","publication_status":"published","citation":{"ieee":"K. Chatterjee, E. Kafshdar Goharshady, P. Novotný, J. Zárevúcky, and D. Zikelic, “On lexicographic proof rules for probabilistic termination,” <i>Formal Aspects of Computing</i>, vol. 35, no. 2. Association for Computing Machinery, 2023.","mla":"Chatterjee, Krishnendu, et al. “On Lexicographic Proof Rules for Probabilistic Termination.” <i>Formal Aspects of Computing</i>, vol. 35, no. 2, 11, Association for Computing Machinery, 2023, doi:<a href=\"https://doi.org/10.1145/3585391\">10.1145/3585391</a>.","apa":"Chatterjee, K., Kafshdar Goharshady, E., Novotný, P., Zárevúcky, J., &#38; Zikelic, D. (2023). On lexicographic proof rules for probabilistic termination. <i>Formal Aspects of Computing</i>. Association for Computing Machinery. <a href=\"https://doi.org/10.1145/3585391\">https://doi.org/10.1145/3585391</a>","ista":"Chatterjee K, Kafshdar Goharshady E, Novotný P, Zárevúcky J, Zikelic D. 2023. On lexicographic proof rules for probabilistic termination. Formal Aspects of Computing. 35(2), 11.","short":"K. Chatterjee, E. Kafshdar Goharshady, P. Novotný, J. Zárevúcky, D. Zikelic, Formal Aspects of Computing 35 (2023).","ama":"Chatterjee K, Kafshdar Goharshady E, Novotný P, Zárevúcky J, Zikelic D. On lexicographic proof rules for probabilistic termination. <i>Formal Aspects of Computing</i>. 2023;35(2). doi:<a href=\"https://doi.org/10.1145/3585391\">10.1145/3585391</a>","chicago":"Chatterjee, Krishnendu, Ehsan Kafshdar Goharshady, Petr Novotný, Jiří Zárevúcky, and Dorde Zikelic. “On Lexicographic Proof Rules for Probabilistic Termination.” <i>Formal Aspects of Computing</i>. Association for Computing Machinery, 2023. <a href=\"https://doi.org/10.1145/3585391\">https://doi.org/10.1145/3585391</a>."},"ec_funded":1,"volume":35,"department":[{"_id":"KrCh"}],"article_processing_charge":"Yes"},{"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"ddc":["550"],"author":[{"last_name":"Shaw","first_name":"Thomas E.","full_name":"Shaw, Thomas E."},{"first_name":"Pascal","last_name":"Buri","full_name":"Buri, Pascal"},{"first_name":"Michael","last_name":"McCarthy","full_name":"McCarthy, Michael"},{"first_name":"Evan S.","last_name":"Miles","full_name":"Miles, Evan S."},{"full_name":"Ayala, Álvaro","last_name":"Ayala","first_name":"Álvaro"},{"full_name":"Pellicciotti, Francesca","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","first_name":"Francesca","orcid":"0000-0002-5554-8087","last_name":"Pellicciotti"}],"acknowledgement":"This work was funded by the EU Horizon 2020 Marie Skłodowska-Curie Actions Grant 101026058. The authors acknowl-edge the dedicated collection of field data by many parties since 2001, including those acknowledged for the cited works on Arolla Glacier. The authors would like to thank Fabienne Meier, Alice Zaugg, Raphael Willi, Maria Grundmann, and Marta Corrà for assistance in the field for the summers of 2021 and 2022. Off-glacier data provided by Grand Dixence SA (Arolla) and MeteoSwiss are kindly acknowledged. Simone Fatichi is thanked for the provision and support in the use of the Tethys-Chloris model. We thank Editor Mathieu Morlighem and two anonymous reviewers whose comments have helped to improve the quality of the manuscript.","issue":"11","date_created":"2024-01-10T09:28:34Z","file_date_updated":"2024-01-16T08:35:02Z","status":"public","doi":"10.1029/2023gl103043","type":"journal_article","oa_version":"Published Version","language":[{"iso":"eng"}],"date_updated":"2024-10-21T06:01:34Z","title":"The decaying near‐surface boundary layer of a retreating alpine glacier","day":"16","file":[{"creator":"dernst","success":1,"content_type":"application/pdf","checksum":"391a3005c95340a0ae129ce4fbdf2bae","file_id":"14805","date_created":"2024-01-16T08:35:02Z","access_level":"open_access","date_updated":"2024-01-16T08:35:02Z","file_name":"2023_GeophysicalResearchLetter_Shaw.pdf","relation":"main_file","file_size":2529327}],"article_number":"e2023GL103043","abstract":[{"text":"The presence of a developed boundary layer decouples a glacier's response from ambient conditions, suggesting that sensitivity to climate change is increased by glacier retreat. To test this hypothesis, we explore six years of distributed meteorological data on a small Swiss glacier in the period 2001–2022. Large glacier fragmentation has occurred since 2001 (−35% area change up to 2022) coinciding with notable frontal retreat, an observed switch from down‐glacier katabatic to up‐glacier valley winds and an increased sensitivity (ratio) of on‐glacier to off‐glacier temperature. As the glacier ceases to develop density‐driven katabatic winds, sensible heat fluxes on the glacier are increasingly determined by the conditions occurring outside the boundary layer of the glacier, sealing the glacier's demise as the climate continues to warm and experience an increased frequency of extreme summers.","lang":"eng"}],"intvolume":"        50","year":"2023","external_id":{"isi":["000999436400001"]},"quality_controlled":"1","keyword":["General Earth and Planetary Sciences","Geophysics"],"isi":1,"scopus_import":"1","publisher":"American Geophysical Union","fulldoi":"https://doi.org/10.1029/2023gl103043","publication_identifier":{"eissn":["1944-8007"],"issn":["0094-8276"]},"_id":"14779","publication":"Geophysical Research Letters","has_accepted_license":"1","oa":1,"department":[{"_id":"FrPe"}],"article_processing_charge":"No","citation":{"chicago":"Shaw, Thomas E., Pascal Buri, Michael McCarthy, Evan S. Miles, Álvaro Ayala, and Francesca Pellicciotti. “The Decaying Near‐surface Boundary Layer of a Retreating Alpine Glacier.” <i>Geophysical Research Letters</i>. American Geophysical Union, 2023. <a href=\"https://doi.org/10.1029/2023gl103043\">https://doi.org/10.1029/2023gl103043</a>.","ama":"Shaw TE, Buri P, McCarthy M, Miles ES, Ayala Á, Pellicciotti F. The decaying near‐surface boundary layer of a retreating alpine glacier. <i>Geophysical Research Letters</i>. 2023;50(11). doi:<a href=\"https://doi.org/10.1029/2023gl103043\">10.1029/2023gl103043</a>","short":"T.E. Shaw, P. Buri, M. McCarthy, E.S. Miles, Á. Ayala, F. Pellicciotti, Geophysical Research Letters 50 (2023).","mla":"Shaw, Thomas E., et al. “The Decaying Near‐surface Boundary Layer of a Retreating Alpine Glacier.” <i>Geophysical Research Letters</i>, vol. 50, no. 11, e2023GL103043, American Geophysical Union, 2023, doi:<a href=\"https://doi.org/10.1029/2023gl103043\">10.1029/2023gl103043</a>.","apa":"Shaw, T. E., Buri, P., McCarthy, M., Miles, E. S., Ayala, Á., &#38; Pellicciotti, F. (2023). The decaying near‐surface boundary layer of a retreating alpine glacier. <i>Geophysical Research Letters</i>. American Geophysical Union. <a href=\"https://doi.org/10.1029/2023gl103043\">https://doi.org/10.1029/2023gl103043</a>","ista":"Shaw TE, Buri P, McCarthy M, Miles ES, Ayala Á, Pellicciotti F. 2023. The decaying near‐surface boundary layer of a retreating alpine glacier. Geophysical Research Letters. 50(11), e2023GL103043.","ieee":"T. E. Shaw, P. Buri, M. McCarthy, E. S. Miles, Á. Ayala, and F. Pellicciotti, “The decaying near‐surface boundary layer of a retreating alpine glacier,” <i>Geophysical Research Letters</i>, vol. 50, no. 11. American Geophysical Union, 2023."},"volume":50,"month":"06","date_published":"2023-06-16T00:00:00Z","publication_status":"published","article_type":"original","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"fulldoi":"https://doi.org/10.1016/j.spa.2023.05.009","publisher":"Elsevier","scopus_import":"1","publication":"Stochastic Processes and their Applications","_id":"14780","publication_identifier":{"issn":["0304-4149"],"eissn":["1879-209X"]},"project":[{"name":"Random matrices beyond Wigner-Dyson-Mehta","grant_number":"101020331","call_identifier":"H2020","_id":"62796744-2b32-11ec-9570-940b20777f1d"}],"arxiv":1,"oa":1,"has_accepted_license":"1","article_processing_charge":"Yes (in subscription journal)","department":[{"_id":"LaEr"}],"volume":163,"ec_funded":1,"citation":{"ama":"Ding X, Ji HC. Spiked multiplicative random matrices and principal components. <i>Stochastic Processes and their Applications</i>. 2023;163:25-60. doi:<a href=\"https://doi.org/10.1016/j.spa.2023.05.009\">10.1016/j.spa.2023.05.009</a>","chicago":"Ding, Xiucai, and Hong Chang Ji. “Spiked Multiplicative Random Matrices and Principal Components.” <i>Stochastic Processes and Their Applications</i>. Elsevier, 2023. <a href=\"https://doi.org/10.1016/j.spa.2023.05.009\">https://doi.org/10.1016/j.spa.2023.05.009</a>.","apa":"Ding, X., &#38; Ji, H. C. (2023). Spiked multiplicative random matrices and principal components. <i>Stochastic Processes and Their Applications</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.spa.2023.05.009\">https://doi.org/10.1016/j.spa.2023.05.009</a>","mla":"Ding, Xiucai, and Hong Chang Ji. “Spiked Multiplicative Random Matrices and Principal Components.” <i>Stochastic Processes and Their Applications</i>, vol. 163, Elsevier, 2023, pp. 25–60, doi:<a href=\"https://doi.org/10.1016/j.spa.2023.05.009\">10.1016/j.spa.2023.05.009</a>.","ista":"Ding X, Ji HC. 2023. Spiked multiplicative random matrices and principal components. Stochastic Processes and their Applications. 163, 25–60.","short":"X. Ding, H.C. Ji, Stochastic Processes and Their Applications 163 (2023) 25–60.","ieee":"X. Ding and H. C. Ji, “Spiked multiplicative random matrices and principal components,” <i>Stochastic Processes and their Applications</i>, vol. 163. Elsevier, pp. 25–60, 2023."},"publication_status":"published","date_published":"2023-09-01T00:00:00Z","month":"09","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","article_type":"original","author":[{"full_name":"Ding, Xiucai","last_name":"Ding","first_name":"Xiucai"},{"first_name":"Hong Chang","id":"dd216c0a-c1f9-11eb-beaf-e9ea9d2de76d","last_name":"Ji","full_name":"Ji, Hong Chang"}],"ddc":["510"],"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"date_created":"2024-01-10T09:29:25Z","acknowledgement":"The authors would like to thank the editor, the associated editor and two anonymous referees for their many critical suggestions which have significantly improved the paper. The authors are also grateful to Zhigang Bao and Ji Oon Lee for many helpful discussions. The first author also wants to thank Hari Bercovici for many useful comments. The first author is partially supported by National Science Foundation DMS-2113489 and the second author is supported by ERC Advanced Grant “RMTBeyond” No. 101020331.","type":"journal_article","status":"public","doi":"10.1016/j.spa.2023.05.009","file_date_updated":"2024-01-16T08:47:31Z","day":"01","date_updated":"2025-07-16T08:01:03Z","title":"Spiked multiplicative random matrices and principal components","oa_version":"Published Version","language":[{"iso":"eng"}],"intvolume":"       163","abstract":[{"lang":"eng","text":"In this paper, we study the eigenvalues and eigenvectors of the spiked invariant multiplicative models when the randomness is from Haar matrices. We establish the limits of the outlier eigenvalues λˆi and the generalized components (⟨v,uˆi⟩ for any deterministic vector v) of the outlier eigenvectors uˆi with optimal convergence rates. Moreover, we prove that the non-outlier eigenvalues stick with those of the unspiked matrices and the non-outlier eigenvectors are delocalized. The results also hold near the so-called BBP transition and for degenerate spikes. On one hand, our results can be regarded as a refinement of the counterparts of [12] under additional regularity conditions. On the other hand, they can be viewed as an analog of [34] by replacing the random matrix with i.i.d. entries with Haar random matrix."}],"file":[{"file_size":1870349,"relation":"main_file","access_level":"open_access","date_updated":"2024-01-16T08:47:31Z","file_name":"2023_StochasticProcAppl_Ding.pdf","creator":"dernst","content_type":"application/pdf","checksum":"46a708b0cd5569a73d0f3d6c3e0a44dc","success":1,"file_id":"14806","date_created":"2024-01-16T08:47:31Z"}],"external_id":{"arxiv":["2302.13502"],"isi":["001113615900001"]},"year":"2023","isi":1,"page":"25-60","keyword":["Applied Mathematics","Modeling and Simulation","Statistics and Probability"],"quality_controlled":"1"},{"doi":"10.1016/j.devcel.2023.06.009","status":"public","type":"journal_article","author":[{"full_name":"Westerich, Kim Joana","first_name":"Kim Joana","last_name":"Westerich"},{"first_name":"Katsiaryna","last_name":"Tarbashevich","full_name":"Tarbashevich, Katsiaryna"},{"full_name":"Schick, Jan","last_name":"Schick","first_name":"Jan"},{"full_name":"Gupta, Antra","first_name":"Antra","last_name":"Gupta"},{"last_name":"Zhu","first_name":"Mingzhao","full_name":"Zhu, Mingzhao"},{"full_name":"Hull, Kenneth","first_name":"Kenneth","last_name":"Hull"},{"first_name":"Daniel","last_name":"Romo","full_name":"Romo, Daniel"},{"full_name":"Zeuschner, Dagmar","first_name":"Dagmar","last_name":"Zeuschner"},{"full_name":"Goudarzi, Mohammad","id":"3384113A-F248-11E8-B48F-1D18A9856A87","first_name":"Mohammad","last_name":"Goudarzi"},{"first_name":"Theresa","last_name":"Gross-Thebing","full_name":"Gross-Thebing, Theresa"},{"last_name":"Raz","first_name":"Erez","full_name":"Raz, Erez"}],"main_file_link":[{"open_access":"1","url":"https://www.biorxiv.org/content/10.1101/2023.07.09.548244"}],"issue":"17","acknowledgement":"We thank Celeste Brennecka for editing and Michal Reichman-Fried for critical comments on the manuscript. We thank Ursula Jordan, Esther Messerschmidt, and Ines Sandbote for technical assistance. This work was supported by funding from the University of Münster (K.J.W., K.T., E.R., A.G., T.G.-T., J.S., and M.G.), the Max Planck Institute for Molecular Biomedicine (D.Z.), the German Research Foundation grant CRU 326 (P2) RA863/12-2 (E.R.), Baylor University (K.H. and D.R.), and the National Institutes of Health grant R35 GM 134910 (D.R.). We thank the referees for insightful comments that helped improve the manuscript.","date_created":"2024-01-10T09:41:21Z","year":"2023","external_id":{"pmid":["37463577"]},"quality_controlled":"1","page":"1578-1592.e5","keyword":["Developmental Biology","Cell Biology","General Biochemistry","Genetics and Molecular Biology","Molecular Biology"],"language":[{"iso":"eng"}],"oa_version":"Preprint","day":"11","date_updated":"2024-01-16T08:56:36Z","title":"Spatial organization and function of RNA molecules within phase-separated condensates in zebrafish are controlled by Dnd1","abstract":[{"text":"Germ granules, condensates of phase-separated RNA and protein, are organelles that are essential for germline development in different organisms. The patterning of the granules and their relevance for germ cell fate are not fully understood. Combining three-dimensional in vivo structural and functional analyses, we study the dynamic spatial organization of molecules within zebrafish germ granules. We find that the localization of RNA molecules to the periphery of the granules, where ribosomes are localized, depends on translational activity at this location. In addition, we find that the vertebrate-specific Dead end (Dnd1) protein is essential for nanos3 RNA localization at the condensates’ periphery. Accordingly, in the absence of Dnd1, or when translation is inhibited, nanos3 RNA translocates into the granule interior, away from the ribosomes, a process that is correlated with the loss of germ cell fate. These findings highlight the relevance of sub-granule compartmentalization for post-transcriptional control and its importance for preserving germ cell totipotency.","lang":"eng"}],"intvolume":"        58","oa":1,"publisher":"Elsevier","fulldoi":"https://doi.org/10.1016/j.devcel.2023.06.009","pmid":1,"_id":"14781","publication_identifier":{"issn":["1534-5807"]},"publication":"Developmental Cell","month":"09","publication_status":"published","date_published":"2023-09-11T00:00:00Z","article_type":"original","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"No","department":[{"_id":"Bio"}],"citation":{"apa":"Westerich, K. J., Tarbashevich, K., Schick, J., Gupta, A., Zhu, M., Hull, K., … Raz, E. (2023). Spatial organization and function of RNA molecules within phase-separated condensates in zebrafish are controlled by Dnd1. <i>Developmental Cell</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.devcel.2023.06.009\">https://doi.org/10.1016/j.devcel.2023.06.009</a>","mla":"Westerich, Kim Joana, et al. “Spatial Organization and Function of RNA Molecules within Phase-Separated Condensates in Zebrafish Are Controlled by Dnd1.” <i>Developmental Cell</i>, vol. 58, no. 17, Elsevier, 2023, p. 1578–1592.e5, doi:<a href=\"https://doi.org/10.1016/j.devcel.2023.06.009\">10.1016/j.devcel.2023.06.009</a>.","ista":"Westerich KJ, Tarbashevich K, Schick J, Gupta A, Zhu M, Hull K, Romo D, Zeuschner D, Goudarzi M, Gross-Thebing T, Raz E. 2023. Spatial organization and function of RNA molecules within phase-separated condensates in zebrafish are controlled by Dnd1. Developmental Cell. 58(17), 1578–1592.e5.","short":"K.J. Westerich, K. Tarbashevich, J. Schick, A. Gupta, M. Zhu, K. Hull, D. Romo, D. Zeuschner, M. Goudarzi, T. Gross-Thebing, E. Raz, Developmental Cell 58 (2023) 1578–1592.e5.","ieee":"K. J. Westerich <i>et al.</i>, “Spatial organization and function of RNA molecules within phase-separated condensates in zebrafish are controlled by Dnd1,” <i>Developmental Cell</i>, vol. 58, no. 17. Elsevier, p. 1578–1592.e5, 2023.","chicago":"Westerich, Kim Joana, Katsiaryna Tarbashevich, Jan Schick, Antra Gupta, Mingzhao Zhu, Kenneth Hull, Daniel Romo, et al. “Spatial Organization and Function of RNA Molecules within Phase-Separated Condensates in Zebrafish Are Controlled by Dnd1.” <i>Developmental Cell</i>. Elsevier, 2023. <a href=\"https://doi.org/10.1016/j.devcel.2023.06.009\">https://doi.org/10.1016/j.devcel.2023.06.009</a>.","ama":"Westerich KJ, Tarbashevich K, Schick J, et al. Spatial organization and function of RNA molecules within phase-separated condensates in zebrafish are controlled by Dnd1. <i>Developmental Cell</i>. 2023;58(17):1578-1592.e5. doi:<a href=\"https://doi.org/10.1016/j.devcel.2023.06.009\">10.1016/j.devcel.2023.06.009</a>"},"volume":58},{"citation":{"mla":"Baldauf, Lucia, et al. “Branched Actin Cortices Reconstituted in Vesicles Sense Membrane Curvature.” <i>Biophysical Journal</i>, vol. 122, no. 11, Elsevier, 2023, pp. 2311–24, doi:<a href=\"https://doi.org/10.1016/j.bpj.2023.02.018\">10.1016/j.bpj.2023.02.018</a>.","apa":"Baldauf, L., Frey, F. F., Arribas Perez, M., Idema, T., &#38; Koenderink, G. H. (2023). Branched actin cortices reconstituted in vesicles sense membrane curvature. <i>Biophysical Journal</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.bpj.2023.02.018\">https://doi.org/10.1016/j.bpj.2023.02.018</a>","ista":"Baldauf L, Frey FF, Arribas Perez M, Idema T, Koenderink GH. 2023. Branched actin cortices reconstituted in vesicles sense membrane curvature. Biophysical Journal. 122(11), 2311–2324.","short":"L. Baldauf, F.F. Frey, M. Arribas Perez, T. Idema, G.H. Koenderink, Biophysical Journal 122 (2023) 2311–2324.","ieee":"L. Baldauf, F. F. Frey, M. Arribas Perez, T. Idema, and G. H. Koenderink, “Branched actin cortices reconstituted in vesicles sense membrane curvature,” <i>Biophysical Journal</i>, vol. 122, no. 11. Elsevier, pp. 2311–2324, 2023.","chicago":"Baldauf, Lucia, Felix F Frey, Marcos Arribas Perez, Timon Idema, and Gijsje H. Koenderink. “Branched Actin Cortices Reconstituted in Vesicles Sense Membrane Curvature.” <i>Biophysical Journal</i>. Elsevier, 2023. <a href=\"https://doi.org/10.1016/j.bpj.2023.02.018\">https://doi.org/10.1016/j.bpj.2023.02.018</a>.","ama":"Baldauf L, Frey FF, Arribas Perez M, Idema T, Koenderink GH. Branched actin cortices reconstituted in vesicles sense membrane curvature. <i>Biophysical Journal</i>. 2023;122(11):2311-2324. doi:<a href=\"https://doi.org/10.1016/j.bpj.2023.02.018\">10.1016/j.bpj.2023.02.018</a>"},"volume":122,"article_processing_charge":"Yes (in subscription journal)","department":[{"_id":"AnSa"}],"article_type":"original","related_material":{"link":[{"url":"https://github.com/BioSoftMatterGroup/actin-curvature-sensing","relation":"software"}]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","month":"06","publication_status":"published","date_published":"2023-06-06T00:00:00Z","publication_identifier":{"issn":["0006-3495"]},"_id":"14782","pmid":1,"publication":"Biophysical Journal","publisher":"Elsevier","fulldoi":"https://doi.org/10.1016/j.bpj.2023.02.018","has_accepted_license":"1","oa":1,"abstract":[{"lang":"eng","text":"The actin cortex is a complex cytoskeletal machinery that drives and responds to changes in cell shape. It must generate or adapt to plasma membrane curvature to facilitate diverse functions such as cell division, migration, and phagocytosis. Due to the complex molecular makeup of the actin cortex, it remains unclear whether actin networks are inherently able to sense and generate membrane curvature, or whether they rely on their diverse binding partners to accomplish this. Here, we show that curvature sensing is an inherent capability of branched actin networks nucleated by Arp2/3 and VCA. We develop a robust method to encapsulate actin inside giant unilamellar vesicles (GUVs) and assemble an actin cortex at the inner surface of the GUV membrane. We show that actin forms a uniform and thin cortical layer when present at high concentration and distinct patches associated with negative membrane curvature at low concentration. Serendipitously, we find that the GUV production method also produces dumbbell-shaped GUVs, which we explain using mathematical modeling in terms of membrane hemifusion of nested GUVs. We find that branched actin networks preferentially assemble at the neck of the dumbbells, which possess a micrometer-range convex curvature comparable with the curvature of the actin patches found in spherical GUVs. Minimal branched actin networks can thus sense membrane curvature, which may help mammalian cells to robustly recruit actin to curved membranes to facilitate diverse cellular functions such as cytokinesis and migration."}],"file":[{"relation":"main_file","file_size":3285810,"file_id":"14807","creator":"dernst","content_type":"application/pdf","success":1,"checksum":"70566e54cd95ea6df340909ad44c5cd5","date_created":"2024-01-16T09:09:29Z","file_name":"2023_BiophysicalJournal_Baldauf.pdf","date_updated":"2024-01-16T09:09:29Z","access_level":"open_access"}],"intvolume":"       122","oa_version":"Published Version","language":[{"iso":"eng"}],"day":"06","date_updated":"2024-01-16T09:20:03Z","title":"Branched actin cortices reconstituted in vesicles sense membrane curvature","license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","quality_controlled":"1","isi":1,"page":"2311-2324","keyword":["Biophysics"],"year":"2023","external_id":{"isi":["001016792600001"],"pmid":["36806830"]},"issue":"11","acknowledgement":"We thank Jeffrey den Haan for protein purification, Kristina Ganzinger (AMOLF) for providing the 10xHis VCA construct, David Kovar (University of Chicago) for the CP constructs, and Michael Way (Crick Institute) for providing purified human Arp2/3 proteins. We are grateful to Iris Lambert for early actin encapsulation experiments that formed the basis for establishing the eDICE method, to Federico Fanalista for acquiring images of dumbbell-shaped GUVs in samples produced by cDICE, and to Tom Aarts for images of dumbbell-shaped GUVs produced by gel-assisted swelling. Lennard van Buren is thanked for his help with image analysis to quantify actin concentrations in GUVs. We thank Kristina Ganzinger (AMOLF) for hosting us to perform pyrene assays in her lab, and Balász Antalicz (AMOLF) for technical assistance with the spectrophotometer. The authors also thank Matthieu Piel and Daniel Fletcher for insightful and inspiring discussions. We acknowledge financial support from The Netherlands Organization of Scientific Research (NWO/OCW) Gravitation program Building a Synthetic Cell (BaSyC) (024.003.019). F.F. gratefully acknowledges funding from the Kavli Synergy program of the Kavli Institute of Nanoscience Delft.","date_created":"2024-01-10T09:45:48Z","tmp":{"short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"author":[{"full_name":"Baldauf, Lucia","last_name":"Baldauf","first_name":"Lucia"},{"full_name":"Frey, Felix F","last_name":"Frey","id":"a0270b37-8f1a-11ec-95c7-8e710c59a4f3","first_name":"Felix F"},{"full_name":"Arribas Perez, Marcos","first_name":"Marcos","last_name":"Arribas Perez"},{"full_name":"Idema, Timon","last_name":"Idema","first_name":"Timon"},{"full_name":"Koenderink, Gijsje H.","first_name":"Gijsje H.","last_name":"Koenderink"}],"ddc":["570"],"file_date_updated":"2024-01-16T09:09:29Z","status":"public","doi":"10.1016/j.bpj.2023.02.018","type":"journal_article"},{"oa":1,"has_accepted_license":"1","publication":"Cells","_id":"14783","publication_identifier":{"issn":["2073-4409"]},"pmid":1,"fulldoi":"https://doi.org/10.3390/cells12081133","publisher":"MDPI","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_type":"original","publication_status":"published","date_published":"2023-04-11T00:00:00Z","month":"04","volume":12,"citation":{"chicago":"Cheung, Giselle T, Oana Chever, Astrid Rollenhagen, Nicole Quenech’du, Pascal Ezan, Joachim H. R. Lübke, and Nathalie Rouach. “Astroglial Connexin 43 Regulates Synaptic Vesicle Release at Hippocampal Synapses.” <i>Cells</i>. MDPI, 2023. <a href=\"https://doi.org/10.3390/cells12081133\">https://doi.org/10.3390/cells12081133</a>.","ama":"Cheung GT, Chever O, Rollenhagen A, et al. Astroglial connexin 43 regulates synaptic vesicle release at hippocampal synapses. <i>Cells</i>. 2023;12(8). doi:<a href=\"https://doi.org/10.3390/cells12081133\">10.3390/cells12081133</a>","ieee":"G. T. Cheung <i>et al.</i>, “Astroglial connexin 43 regulates synaptic vesicle release at hippocampal synapses,” <i>Cells</i>, vol. 12, no. 8. MDPI, 2023.","short":"G.T. Cheung, O. Chever, A. Rollenhagen, N. Quenech’du, P. Ezan, J.H.R. Lübke, N. Rouach, Cells 12 (2023).","ista":"Cheung GT, Chever O, Rollenhagen A, Quenech’du N, Ezan P, Lübke JHR, Rouach N. 2023. Astroglial connexin 43 regulates synaptic vesicle release at hippocampal synapses. Cells. 12(8), 1133.","apa":"Cheung, G. T., Chever, O., Rollenhagen, A., Quenech’du, N., Ezan, P., Lübke, J. H. R., &#38; Rouach, N. (2023). Astroglial connexin 43 regulates synaptic vesicle release at hippocampal synapses. <i>Cells</i>. MDPI. <a href=\"https://doi.org/10.3390/cells12081133\">https://doi.org/10.3390/cells12081133</a>","mla":"Cheung, Giselle T., et al. “Astroglial Connexin 43 Regulates Synaptic Vesicle Release at Hippocampal Synapses.” <i>Cells</i>, vol. 12, no. 8, 1133, MDPI, 2023, doi:<a href=\"https://doi.org/10.3390/cells12081133\">10.3390/cells12081133</a>."},"article_processing_charge":"Yes","department":[{"_id":"SiHi"}],"type":"journal_article","file_date_updated":"2024-01-16T09:26:52Z","status":"public","doi":"10.3390/cells12081133","date_created":"2024-01-10T09:46:35Z","acknowledgement":"This research was funded by grants from the European Research Council (Consolidator grant #683154) and European Union’s Horizon 2020 research and innovation program (Marie Sklodowska-Curie Innovative Training Networks, grant #722053, EU-GliaPhD) to N.R., as well as from FP7-PEOPLE Marie Curie Intra-European Fellowship for career development (grant #622289) to G.C. We thank Elena Dossi, Grégory Ghézali, and Jérémie Teillon for support with setting up the MEA system for the two-photon microscope. We would also like to thank Tayfun Palaz for their technical assistance with the EM preparations.","issue":"8","ddc":["570"],"author":[{"full_name":"Cheung, Giselle T","last_name":"Cheung","orcid":"0000-0001-8457-2572","id":"471195F6-F248-11E8-B48F-1D18A9856A87","first_name":"Giselle T"},{"last_name":"Chever","first_name":"Oana","full_name":"Chever, Oana"},{"full_name":"Rollenhagen, Astrid","first_name":"Astrid","last_name":"Rollenhagen"},{"first_name":"Nicole","last_name":"Quenech’du","full_name":"Quenech’du, Nicole"},{"full_name":"Ezan, Pascal","last_name":"Ezan","first_name":"Pascal"},{"first_name":"Joachim H. R.","last_name":"Lübke","full_name":"Lübke, Joachim H. R."},{"full_name":"Rouach, Nathalie","first_name":"Nathalie","last_name":"Rouach"}],"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"keyword":["General Medicine"],"isi":1,"quality_controlled":"1","external_id":{"isi":["000977445700001"],"pmid":["37190042"]},"year":"2023","intvolume":"        12","file":[{"file_size":7931643,"relation":"main_file","file_name":"2023_Cells_Cheung.pdf","date_updated":"2024-01-16T09:26:52Z","access_level":"open_access","file_id":"14808","creator":"dernst","success":1,"content_type":"application/pdf","checksum":"6798cd75d8857976fbc58a43fd173d68","date_created":"2024-01-16T09:26:52Z"}],"article_number":"1133","abstract":[{"text":"Connexin 43, an astroglial gap junction protein, is enriched in perisynaptic astroglial processes and plays major roles in synaptic transmission. We have previously found that astroglial Cx43 controls synaptic glutamate levels and allows for activity-dependent glutamine release to sustain physiological synaptic transmissions and cognitiogns. However, whether Cx43 is important for the release of synaptic vesicles, which is a critical component of synaptic efficacy, remains unanswered. Here, using transgenic mice with a glial conditional knockout of Cx43 (Cx43−/−), we investigate whether and how astrocytes regulate the release of synaptic vesicles from hippocampal synapses. We report that CA1 pyramidal neurons and their synapses develop normally in the absence of astroglial Cx43. However, a significant impairment in synaptic vesicle distribution and release dynamics were observed. In particular, the FM1-43 assays performed using two-photon live imaging and combined with multi-electrode array stimulation in acute hippocampal slices, revealed a slower rate of synaptic vesicle release in Cx43−/− mice. Furthermore, paired-pulse recordings showed that synaptic vesicle release probability was also reduced and is dependent on glutamine supply via Cx43 hemichannel (HC). Taken together, we have uncovered a role for Cx43 in regulating presynaptic functions by controlling the rate and probability of synaptic vesicle release. Our findings further highlight the significance of astroglial Cx43 in synaptic transmission and efficacy.","lang":"eng"}],"date_updated":"2024-01-16T09:29:35Z","title":"Astroglial connexin 43 regulates synaptic vesicle release at hippocampal synapses","day":"11","oa_version":"Published Version","language":[{"iso":"eng"}]},{"status":"public","file_date_updated":"2024-01-16T09:35:28Z","doi":"10.1126/sciadv.adg1610","type":"journal_article","issue":"34","acknowledgement":"This work was supported by a postdoctoral fellowship from the Swedish Society for Medical Research to J.R., a CAPES-STINT joint grant to R.G.G. and L.S.W., a PhD fellowship from Karolinska Institutet (KID) to E.D., a PhD fellowship from Fundação para a Ciência e a Tecnologia and European Social Fund to M.M.S.O., the program of fundamental research (theme 65.1) of the Institute for Biomedical Problems of the Russian Academy of Sciences (IBMP RAS) to A.A.S., S.M.S., V.A.S., O.V.K., D.D.V., K.D.O., M.P.R., and S.A.P., the Tamkeen under the NYU Abu Dhabi Research Institute Award to the NYUAD Center for Genomics and Systems Biology (ADHPG-CGSB) to P.P., the Knut and Alice Wallenberg foundation to C.K., the Swedish National Space Agency to N.V.K. and L.S.W., Swedish Research Council, Gösta Fraenckel Foundation, and Karolinska Institutet to L.S.W.","date_created":"2024-01-10T09:48:01Z","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"ddc":["570"],"author":[{"full_name":"Gallardo-Dodd, Carlos J.","last_name":"Gallardo-Dodd","first_name":"Carlos J."},{"first_name":"Christian","last_name":"Oertlin","full_name":"Oertlin, Christian"},{"full_name":"Record, Julien","last_name":"Record","first_name":"Julien"},{"full_name":"Galvani, Rômulo G.","first_name":"Rômulo G.","last_name":"Galvani"},{"last_name":"Sommerauer","first_name":"Christian","full_name":"Sommerauer, Christian"},{"full_name":"Kuznetsov, Nikolai V.","first_name":"Nikolai V.","last_name":"Kuznetsov"},{"last_name":"Doukoumopoulos","first_name":"Evangelos","full_name":"Doukoumopoulos, Evangelos"},{"first_name":"Liaqat","last_name":"Ali","full_name":"Ali, Liaqat"},{"first_name":"Mariana M. S.","last_name":"Oliveira","full_name":"Oliveira, Mariana M. S."},{"full_name":"Seitz, Christina","last_name":"Seitz","first_name":"Christina"},{"first_name":"Mathias","id":"4986e21c-eb97-11eb-a6c2-a4ef0b629971","last_name":"Percipalle","full_name":"Percipalle, Mathias"},{"last_name":"Nikić","first_name":"Tijana","full_name":"Nikić, Tijana"},{"last_name":"Sadova","first_name":"Anastasia A.","full_name":"Sadova, Anastasia A."},{"last_name":"Shulgina","first_name":"Sofia M.","full_name":"Shulgina, Sofia M."},{"full_name":"Shmarov, Vjacheslav A.","first_name":"Vjacheslav A.","last_name":"Shmarov"},{"full_name":"Kutko, Olga V.","first_name":"Olga V.","last_name":"Kutko"},{"last_name":"Vlasova","first_name":"Daria D.","full_name":"Vlasova, Daria D."},{"full_name":"Orlova, Kseniya D.","last_name":"Orlova","first_name":"Kseniya D."},{"first_name":"Marina P.","last_name":"Rykova","full_name":"Rykova, Marina P."},{"last_name":"Andersson","first_name":"John","full_name":"Andersson, John"},{"full_name":"Percipalle, Piergiorgio","first_name":"Piergiorgio","last_name":"Percipalle"},{"first_name":"Claudia","last_name":"Kutter","full_name":"Kutter, Claudia"},{"first_name":"Sergey A.","last_name":"Ponomarev","full_name":"Ponomarev, Sergey A."},{"full_name":"Westerberg, Lisa S.","last_name":"Westerberg","first_name":"Lisa S."}],"quality_controlled":"1","keyword":["Multidisciplinary"],"isi":1,"year":"2023","external_id":{"isi":["001054596800007"],"pmid":["37624890"]},"file":[{"file_id":"14809","checksum":"b9072e20e2d5d9d34d2c53319bafee41","creator":"dernst","success":1,"content_type":"application/pdf","date_created":"2024-01-16T09:35:28Z","date_updated":"2024-01-16T09:35:28Z","file_name":"2023_ScienceAdvances_GallardoDodd.pdf","access_level":"open_access","relation":"main_file","file_size":1596639}],"abstract":[{"lang":"eng","text":"The next steps of deep space exploration are manned missions to Moon and Mars. For safe space missions for crew members, it is important to understand the impact of space flight on the immune system. We studied the effects of 21 days dry immersion (DI) exposure on the transcriptomes of T cells isolated from blood samples of eight healthy volunteers. Samples were collected 7 days before DI, at day 7, 14, and 21 during DI, and 7 days after DI. RNA sequencing of CD3+T cells revealed transcriptional alterations across all time points, with most changes occurring 14 days after DI exposure. At day 21, T cells showed evidence of adaptation with a transcriptional profile resembling that of 7 days before DI. At 7 days after DI, T cells again changed their transcriptional profile. These data suggest that T cells adapt by rewiring their transcriptomes in response to simulated weightlessness and that remodeling cues persist when reexposed to normal gravity."}],"article_number":"adg1610","intvolume":"         9","language":[{"iso":"eng"}],"oa_version":"Published Version","date_updated":"2024-09-09T08:03:13Z","title":"Exposure of volunteers to microgravity by dry immersion bed over 21 days results in gene expression changes and adaptation of T cells","day":"25","has_accepted_license":"1","oa":1,"_id":"14784","publication_identifier":{"issn":["2375-2548"]},"pmid":1,"publication":"Science Advances","publisher":"American Association for the Advancement of Science","fulldoi":"https://doi.org/10.1126/sciadv.adg1610","article_type":"original","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","month":"08","date_published":"2023-08-25T00:00:00Z","publication_status":"published","citation":{"ama":"Gallardo-Dodd CJ, Oertlin C, Record J, et al. Exposure of volunteers to microgravity by dry immersion bed over 21 days results in gene expression changes and adaptation of T cells. <i>Science Advances</i>. 2023;9(34). doi:<a href=\"https://doi.org/10.1126/sciadv.adg1610\">10.1126/sciadv.adg1610</a>","chicago":"Gallardo-Dodd, Carlos J., Christian Oertlin, Julien Record, Rômulo G. Galvani, Christian Sommerauer, Nikolai V. Kuznetsov, Evangelos Doukoumopoulos, et al. “Exposure of Volunteers to Microgravity by Dry Immersion Bed over 21 Days Results in Gene Expression Changes and Adaptation of T Cells.” <i>Science Advances</i>. American Association for the Advancement of Science, 2023. <a href=\"https://doi.org/10.1126/sciadv.adg1610\">https://doi.org/10.1126/sciadv.adg1610</a>.","ieee":"C. J. Gallardo-Dodd <i>et al.</i>, “Exposure of volunteers to microgravity by dry immersion bed over 21 days results in gene expression changes and adaptation of T cells,” <i>Science Advances</i>, vol. 9, no. 34. American Association for the Advancement of Science, 2023.","short":"C.J. Gallardo-Dodd, C. Oertlin, J. Record, R.G. Galvani, C. Sommerauer, N.V. Kuznetsov, E. Doukoumopoulos, L. Ali, M.M.S. Oliveira, C. Seitz, M. Percipalle, T. Nikić, A.A. Sadova, S.M. Shulgina, V.A. Shmarov, O.V. Kutko, D.D. Vlasova, K.D. Orlova, M.P. Rykova, J. Andersson, P. Percipalle, C. Kutter, S.A. Ponomarev, L.S. Westerberg, Science Advances 9 (2023).","ista":"Gallardo-Dodd CJ, Oertlin C, Record J, Galvani RG, Sommerauer C, Kuznetsov NV, Doukoumopoulos E, Ali L, Oliveira MMS, Seitz C, Percipalle M, Nikić T, Sadova AA, Shulgina SM, Shmarov VA, Kutko OV, Vlasova DD, Orlova KD, Rykova MP, Andersson J, Percipalle P, Kutter C, Ponomarev SA, Westerberg LS. 2023. Exposure of volunteers to microgravity by dry immersion bed over 21 days results in gene expression changes and adaptation of T cells. Science Advances. 9(34), adg1610.","mla":"Gallardo-Dodd, Carlos J., et al. “Exposure of Volunteers to Microgravity by Dry Immersion Bed over 21 Days Results in Gene Expression Changes and Adaptation of T Cells.” <i>Science Advances</i>, vol. 9, no. 34, adg1610, American Association for the Advancement of Science, 2023, doi:<a href=\"https://doi.org/10.1126/sciadv.adg1610\">10.1126/sciadv.adg1610</a>.","apa":"Gallardo-Dodd, C. J., Oertlin, C., Record, J., Galvani, R. G., Sommerauer, C., Kuznetsov, N. V., … Westerberg, L. S. (2023). Exposure of volunteers to microgravity by dry immersion bed over 21 days results in gene expression changes and adaptation of T cells. <i>Science Advances</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/sciadv.adg1610\">https://doi.org/10.1126/sciadv.adg1610</a>"},"volume":9,"department":[{"_id":"FlSc"}],"article_processing_charge":"Yes"},{"page":"656-668","keyword":["Agricultural and Biological Sciences (miscellaneous)","Ecology","Evolution","Behavior and Systematics"],"isi":1,"quality_controlled":"1","external_id":{"pmid":["37794696"],"isi":["001080203100001"]},"year":"2023","intvolume":"        15","file":[{"date_created":"2024-01-16T09:42:10Z","success":1,"content_type":"application/pdf","creator":"dernst","checksum":"d09ebb68fee61f4e2e09ec286c9cf1d3","file_id":"14810","access_level":"open_access","file_name":"2023_EnvirMicroBiolReports_Nies.pdf","date_updated":"2024-01-16T09:42:10Z","relation":"main_file","file_size":1518350}],"abstract":[{"lang":"eng","text":"Small cryptic plasmids have no clear effect on the host fitness and their functional repertoire remains obscure. The naturally competent cyanobacterium Synechocystis sp. PCC 6803 harbours several small cryptic plasmids; whether their evolution with this species is supported by horizontal transfer remains understudied. Here, we show that the small cryptic plasmid DNA is transferred in the population exclusively by natural transformation, where the transfer frequency of plasmid‐encoded genes is similar to that of chromosome‐encoded genes. Establishing a system to follow gene transfer, we compared the transfer frequency of genes encoded in cryptic plasmids pCA2.4 (2378 bp) and pCB2.4 (2345 bp) within and between populations of two <jats:italic>Synechocystis</jats:italic> sp. PCC 6803 labtypes (termed Kiel and Sevilla). Our results reveal that plasmid gene transfer frequency depends on the recipient labtype. Furthermore, gene transfer via whole plasmid uptake in the Sevilla labtype ranged among the lowest detected transfer rates in our experiments. Our study indicates that horizontal DNA transfer via natural transformation is frequent in the evolution of small cryptic plasmids that reside in naturally competent organisms. Furthermore, we suggest that the contribution of natural transformation to cryptic plasmid persistence in Synechocystis is limited."}],"title":"Role of natural transformation in the evolution of small cryptic plasmids in Synechocystis sp. PCC 6803","date_updated":"2024-01-16T09:46:12Z","day":"01","oa_version":"Published Version","language":[{"iso":"eng"}],"type":"journal_article","file_date_updated":"2024-01-16T09:42:10Z","doi":"10.1111/1758-2229.13203","status":"public","date_created":"2024-01-10T10:41:07Z","issue":"6","acknowledgement":"We thank the lab of Francisco Javier Florencio Bel-lido, Sevilla, Spain for supplying theSynechocystislabtype Sevilla used in this work and the lab of MartinHagemann, Rostock, Germany for supplying the pIGAplasmidusedinthiswork.WethankNilsHülterforfruitful discussions. We thank Fenna Stücker forgraphical illustrations and Katrin Schumann, FennaStücker,  and  Lidusha  Manivannan  for  technicalsupport.\r\nChilean National Agency for Research andDevelopment (ANID), Grant/Award Number:21191763; DeutscheForschungsgemeinschaft, Grant/AwardNumbers: 456882089, RTG2501; EuropeanResearch Council (ERC), Grant/AwardNumber: 101043835","ddc":["570"],"author":[{"full_name":"Nies, Fabian","first_name":"Fabian","last_name":"Nies"},{"first_name":"Tanita","last_name":"Wein","full_name":"Wein, Tanita"},{"first_name":"Dustin M.","last_name":"Hanke","full_name":"Hanke, Dustin M."},{"first_name":"Benjamin L","id":"b4eb62ef-ac72-11ed-9503-ed3b4d66c083","orcid":"0000-0002-3461-5391","last_name":"Springstein","full_name":"Springstein, Benjamin L"},{"full_name":"Alcorta, Jaime","last_name":"Alcorta","first_name":"Jaime"},{"last_name":"Taubenheim","first_name":"Claudia","full_name":"Taubenheim, Claudia"},{"full_name":"Dagan, Tal","last_name":"Dagan","first_name":"Tal"}],"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_type":"original","date_published":"2023-12-01T00:00:00Z","publication_status":"published","month":"12","volume":15,"citation":{"chicago":"Nies, Fabian, Tanita Wein, Dustin M. Hanke, Benjamin L Springstein, Jaime Alcorta, Claudia Taubenheim, and Tal Dagan. “Role of Natural Transformation in the Evolution of Small Cryptic Plasmids in Synechocystis Sp. PCC 6803.” <i>Environmental Microbiology Reports</i>. Wiley, 2023. <a href=\"https://doi.org/10.1111/1758-2229.13203\">https://doi.org/10.1111/1758-2229.13203</a>.","ama":"Nies F, Wein T, Hanke DM, et al. Role of natural transformation in the evolution of small cryptic plasmids in Synechocystis sp. PCC 6803. <i>Environmental Microbiology Reports</i>. 2023;15(6):656-668. doi:<a href=\"https://doi.org/10.1111/1758-2229.13203\">10.1111/1758-2229.13203</a>","short":"F. Nies, T. Wein, D.M. Hanke, B.L. Springstein, J. Alcorta, C. Taubenheim, T. Dagan, Environmental Microbiology Reports 15 (2023) 656–668.","apa":"Nies, F., Wein, T., Hanke, D. M., Springstein, B. L., Alcorta, J., Taubenheim, C., &#38; Dagan, T. (2023). Role of natural transformation in the evolution of small cryptic plasmids in Synechocystis sp. PCC 6803. <i>Environmental Microbiology Reports</i>. Wiley. <a href=\"https://doi.org/10.1111/1758-2229.13203\">https://doi.org/10.1111/1758-2229.13203</a>","ista":"Nies F, Wein T, Hanke DM, Springstein BL, Alcorta J, Taubenheim C, Dagan T. 2023. Role of natural transformation in the evolution of small cryptic plasmids in Synechocystis sp. PCC 6803. Environmental Microbiology Reports. 15(6), 656–668.","mla":"Nies, Fabian, et al. “Role of Natural Transformation in the Evolution of Small Cryptic Plasmids in Synechocystis Sp. PCC 6803.” <i>Environmental Microbiology Reports</i>, vol. 15, no. 6, Wiley, 2023, pp. 656–68, doi:<a href=\"https://doi.org/10.1111/1758-2229.13203\">10.1111/1758-2229.13203</a>.","ieee":"F. Nies <i>et al.</i>, “Role of natural transformation in the evolution of small cryptic plasmids in Synechocystis sp. PCC 6803,” <i>Environmental Microbiology Reports</i>, vol. 15, no. 6. Wiley, pp. 656–668, 2023."},"article_processing_charge":"Yes (in subscription journal)","department":[{"_id":"MaLo"}],"oa":1,"has_accepted_license":"1","publication":"Environmental Microbiology Reports","_id":"14785","publication_identifier":{"eissn":["1758-2229"]},"pmid":1,"fulldoi":"https://doi.org/10.1111/1758-2229.13203","publisher":"Wiley"}]