[{"department":[{"_id":"JoDa"}],"external_id":{"isi":["000625600600007"],"pmid":["33674797"]},"date_updated":"2026-06-18T19:43:50Z","doi":"10.1038/s41592-021-01087-6","oa_version":"Published Version","_id":"9258","ddc":["570"],"issue":"3","pmid":1,"year":"2021","article_type":"letter_note","type":"journal_article","publisher":"Springer Nature","date_created":"2021-03-21T23:01:20Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","date_published":"2021-03-01T00:00:00Z","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/s41592-021-01087-6"}],"day":"01","quality_controlled":"1","publication":"Nature Methods","intvolume":" 18","title":"Pycro-Manager: Open-source software for customized and reproducible microscope control","publication_status":"published","volume":18,"scopus_import":"1","month":"03","publication_identifier":{"issn":["1548-7091"],"eissn":["1548-7105"]},"oa":1,"acknowledgement":"We thank S. van der Walt and K. Marchuk for discussion during development. This project was funded by Packard Fellowship and Chan Zuckerberg Biohub Investigator Awards to L.W.; STROBE: A NSF Science and Technology Center; an NSF Graduate Research Fellowship awarded to H.P.; a Berkeley Institute for Data Science/UCSF Bakar Computational Health Sciences Institute Fellowship awarded to H.P. with support from the Koret Foundation, the Gordon and Betty Moore Foundation, and the Alfred P. Sloan Foundation to the University of California, Berkeley. K.W.E., B.L. and M.T. were funded by the Chan Zuckerberg Initiative and NIH grant P41GM135019.","author":[{"last_name":"Pinkard","first_name":"Henry","full_name":"Pinkard, Henry"},{"last_name":"Stuurman","first_name":"Nico","full_name":"Stuurman, Nico"},{"full_name":"Ivanov, Ivan E.","first_name":"Ivan E.","last_name":"Ivanov"},{"first_name":"Nicholas M.","last_name":"Anthony","full_name":"Anthony, Nicholas M."},{"full_name":"Ouyang, Wei","last_name":"Ouyang","first_name":"Wei"},{"first_name":"Bin","last_name":"Li","full_name":"Li, Bin"},{"first_name":"Bin","last_name":"Yang","full_name":"Yang, Bin"},{"last_name":"Tsuchida","first_name":"Mark A.","full_name":"Tsuchida, Mark A."},{"first_name":"Bryant","last_name":"Chhun","full_name":"Chhun, Bryant"},{"full_name":"Zhang, Grace","last_name":"Zhang","first_name":"Grace"},{"full_name":"Mei, Ryan","last_name":"Mei","first_name":"Ryan"},{"full_name":"Anderson, Michael","first_name":"Michael","last_name":"Anderson"},{"first_name":"Douglas P.","last_name":"Shepherd","full_name":"Shepherd, Douglas P."},{"full_name":"Hunt-Isaak, Ian","last_name":"Hunt-Isaak","first_name":"Ian"},{"full_name":"Dunn, Raymond L.","first_name":"Raymond L.","last_name":"Dunn"},{"first_name":"Wiebke","id":"425C1CE8-F248-11E8-B48F-1D18A9856A87","last_name":"Jahr","full_name":"Jahr, Wiebke","orcid":"0000-0003-0201-2315"},{"full_name":"Kato, Saul","first_name":"Saul","last_name":"Kato"},{"full_name":"Royer, Loïc A.","last_name":"Royer","first_name":"Loïc A."},{"first_name":"Jay R.","last_name":"Thiagarajah","full_name":"Thiagarajah, Jay R."},{"full_name":"Eliceiri, Kevin W.","first_name":"Kevin W.","last_name":"Eliceiri"},{"last_name":"Lundberg","first_name":"Emma","full_name":"Lundberg, Emma"},{"full_name":"Mehta, Shalin B.","first_name":"Shalin B.","last_name":"Mehta"},{"full_name":"Waller, Laura","first_name":"Laura","last_name":"Waller"}],"language":[{"iso":"eng"}],"page":"226-228","citation":{"short":"H. Pinkard, N. Stuurman, I.E. Ivanov, N.M. Anthony, W. Ouyang, B. Li, B. Yang, M.A. Tsuchida, B. Chhun, G. Zhang, R. Mei, M. Anderson, D.P. Shepherd, I. Hunt-Isaak, R.L. Dunn, W. Jahr, S. Kato, L.A. Royer, J.R. Thiagarajah, K.W. Eliceiri, E. Lundberg, S.B. Mehta, L. Waller, Nature Methods 18 (2021) 226–228.","apa":"Pinkard, H., Stuurman, N., Ivanov, I. E., Anthony, N. M., Ouyang, W., Li, B., … Waller, L. (2021). Pycro-Manager: Open-source software for customized and reproducible microscope control. Nature Methods. Springer Nature. https://doi.org/10.1038/s41592-021-01087-6","ama":"Pinkard H, Stuurman N, Ivanov IE, et al. Pycro-Manager: Open-source software for customized and reproducible microscope control. Nature Methods. 2021;18(3):226-228. doi:10.1038/s41592-021-01087-6","ista":"Pinkard H, Stuurman N, Ivanov IE, Anthony NM, Ouyang W, Li B, Yang B, Tsuchida MA, Chhun B, Zhang G, Mei R, Anderson M, Shepherd DP, Hunt-Isaak I, Dunn RL, Jahr W, Kato S, Royer LA, Thiagarajah JR, Eliceiri KW, Lundberg E, Mehta SB, Waller L. 2021. Pycro-Manager: Open-source software for customized and reproducible microscope control. Nature Methods. 18(3), 226–228.","chicago":"Pinkard, Henry, Nico Stuurman, Ivan E. Ivanov, Nicholas M. Anthony, Wei Ouyang, Bin Li, Bin Yang, et al. “Pycro-Manager: Open-Source Software for Customized and Reproducible Microscope Control.” Nature Methods. Springer Nature, 2021. https://doi.org/10.1038/s41592-021-01087-6.","ieee":"H. Pinkard et al., “Pycro-Manager: Open-source software for customized and reproducible microscope control,” Nature Methods, vol. 18, no. 3. Springer Nature, pp. 226–228, 2021.","mla":"Pinkard, Henry, et al. “Pycro-Manager: Open-Source Software for Customized and Reproducible Microscope Control.” Nature Methods, vol. 18, no. 3, Springer Nature, 2021, pp. 226–28, doi:10.1038/s41592-021-01087-6."},"isi":1,"article_processing_charge":"No"},{"oa":1,"acknowledgement":"This work was supported by Sigrid Juselius fellowship (KV), University of Helsinki 3-year research grant (KV), Academy of Finland Research fellow funding (315710, to KV), the European Research Council (ERC CoG 724373 to MS), and by the Austrian Science foundation (FWF) (Y564-B12 START award to MS).\r\nTaija Mäkinen is acknowledged for providing Prox1CreERT2 transgenic mice and Yu Yamaguchi for providing the conditional Ext1 mouse strain.","author":[{"full_name":"Vaahtomeri, Kari","orcid":"0000-0001-7829-3518","id":"368EE576-F248-11E8-B48F-1D18A9856A87","first_name":"Kari","last_name":"Vaahtomeri"},{"full_name":"Moussion, Christine","last_name":"Moussion","id":"3356F664-F248-11E8-B48F-1D18A9856A87","first_name":"Christine"},{"id":"4E01D6B4-F248-11E8-B48F-1D18A9856A87","first_name":"Robert","last_name":"Hauschild","full_name":"Hauschild, Robert","orcid":"0000-0001-9843-3522"},{"orcid":"0000-0002-6620-9179","full_name":"Sixt, Michael K","last_name":"Sixt","first_name":"Michael K","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87"}],"language":[{"iso":"eng"}],"project":[{"name":"Cellular Navigation Along Spatial Gradients","call_identifier":"H2020","_id":"25FE9508-B435-11E9-9278-68D0E5697425","grant_number":"724373"},{"grant_number":"Y 564-B12","call_identifier":"FWF","name":"Cytoskeletal force generation and force transduction of migrating leukocytes","_id":"25A8E5EA-B435-11E9-9278-68D0E5697425"}],"citation":{"mla":"Vaahtomeri, Kari, et al. “Shape and Function of Interstitial Chemokine CCL21 Gradients Are Independent of Heparan Sulfates Produced by Lymphatic Endothelium.” Frontiers in Immunology, vol. 12, 630002, Frontiers, 2021, doi:10.3389/fimmu.2021.630002.","ieee":"K. Vaahtomeri, C. Moussion, R. Hauschild, and M. K. Sixt, “Shape and function of interstitial chemokine CCL21 gradients are independent of heparan sulfates produced by lymphatic endothelium,” Frontiers in Immunology, vol. 12. Frontiers, 2021.","short":"K. Vaahtomeri, C. Moussion, R. Hauschild, M.K. Sixt, Frontiers in Immunology 12 (2021).","ama":"Vaahtomeri K, Moussion C, Hauschild R, Sixt MK. Shape and function of interstitial chemokine CCL21 gradients are independent of heparan sulfates produced by lymphatic endothelium. Frontiers in Immunology. 2021;12. doi:10.3389/fimmu.2021.630002","apa":"Vaahtomeri, K., Moussion, C., Hauschild, R., & Sixt, M. K. (2021). Shape and function of interstitial chemokine CCL21 gradients are independent of heparan sulfates produced by lymphatic endothelium. Frontiers in Immunology. Frontiers. https://doi.org/10.3389/fimmu.2021.630002","chicago":"Vaahtomeri, Kari, Christine Moussion, Robert Hauschild, and Michael K Sixt. “Shape and Function of Interstitial Chemokine CCL21 Gradients Are Independent of Heparan Sulfates Produced by Lymphatic Endothelium.” Frontiers in Immunology. Frontiers, 2021. https://doi.org/10.3389/fimmu.2021.630002.","ista":"Vaahtomeri K, Moussion C, Hauschild R, Sixt MK. 2021. Shape and function of interstitial chemokine CCL21 gradients are independent of heparan sulfates produced by lymphatic endothelium. Frontiers in Immunology. 12, 630002."},"isi":1,"article_processing_charge":"No","volume":12,"scopus_import":"1","month":"02","publication_identifier":{"eissn":["1664-3224"]},"ec_funded":1,"publication":"Frontiers in Immunology","abstract":[{"lang":"eng","text":"Gradients of chemokines and growth factors guide migrating cells and morphogenetic processes. Migration of antigen-presenting dendritic cells from the interstitium into the lymphatic system is dependent on chemokine CCL21, which is secreted by endothelial cells of the lymphatic capillary, binds heparan sulfates and forms gradients decaying into the interstitium. Despite the importance of CCL21 gradients, and chemokine gradients in general, the mechanisms of gradient formation are unclear. Studies on fibroblast growth factors have shown that limited diffusion is crucial for gradient formation. Here, we used the mouse dermis as a model tissue to address the necessity of CCL21 anchoring to lymphatic capillary heparan sulfates in the formation of interstitial CCL21 gradients. Surprisingly, the absence of lymphatic endothelial heparan sulfates resulted only in a modest decrease of CCL21 levels at the lymphatic capillaries and did neither affect interstitial CCL21 gradient shape nor dendritic cell migration toward lymphatic capillaries. Thus, heparan sulfates at the level of the lymphatic endothelium are dispensable for the formation of a functional CCL21 gradient."}],"intvolume":" 12","has_accepted_license":"1","corr_author":"1","publication_status":"published","title":"Shape and function of interstitial chemokine CCL21 gradients are independent of heparan sulfates produced by lymphatic endothelium","day":"25","quality_controlled":"1","date_created":"2021-03-21T23:01:20Z","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","status":"public","date_published":"2021-02-25T00:00:00Z","ddc":["570"],"pmid":1,"year":"2021","license":"https://creativecommons.org/licenses/by/4.0/","type":"journal_article","article_type":"original","publisher":"Frontiers","doi":"10.3389/fimmu.2021.630002","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"file_date_updated":"2021-03-22T12:08:26Z","oa_version":"Published Version","_id":"9259","article_number":"630002","file":[{"checksum":"663f5a48375e42afa4bfef58d42ec186","access_level":"open_access","date_updated":"2021-03-22T12:08:26Z","creator":"dernst","file_name":"2021_FrontiersImmumo_Vaahtomeri.pdf","file_size":3740146,"file_id":"9277","relation":"main_file","date_created":"2021-03-22T12:08:26Z","content_type":"application/pdf","success":1}],"department":[{"_id":"MiSi"},{"_id":"Bio"}],"external_id":{"pmid":["33717158"],"isi":["000627134400001"]},"date_updated":"2025-04-14T07:42:07Z"},{"department":[{"_id":"CampIT"}],"date_updated":"2023-08-07T14:20:26Z","external_id":{"pmid":["33741589"],"isi":["000633443000011"]},"tmp":{"name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","image":"/images/cc_by_nc.png","short":"CC BY-NC (4.0)"},"doi":"10.1126/sciadv.abd9153","article_number":"eabd9153","_id":"9262","file":[{"access_level":"open_access","date_updated":"2021-03-22T12:49:00Z","checksum":"737624cd0e630ffa7c52797a690500e3","file_name":"2021_ScienceAdv_Mbianda.pdf","file_size":837156,"file_id":"9280","creator":"dernst","relation":"main_file","date_created":"2021-03-22T12:49:00Z","success":1,"content_type":"application/pdf"}],"file_date_updated":"2021-03-22T12:49:00Z","oa_version":"Published Version","year":"2021","license":"https://creativecommons.org/licenses/by-nc/4.0/","ddc":["570"],"pmid":1,"issue":"12","article_type":"original","type":"journal_article","publisher":"American Association for the Advancement of Science","date_created":"2021-03-22T07:14:03Z","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","status":"public","date_published":"2021-03-19T00:00:00Z","quality_controlled":"1","day":"19","has_accepted_license":"1","publication_status":"published","title":"Optimal anchoring of a foldamer inhibitor of ASF1 histone chaperone through backbone plasticity","publication":"Science Advances","abstract":[{"text":"Sequence-specific oligomers with predictable folding patterns, i.e., foldamers, provide new opportunities to mimic α-helical peptides and design inhibitors of protein-protein interactions. One major hurdle of this strategy is to retain the correct orientation of key side chains involved in protein surface recognition. Here, we show that the structural plasticity of a foldamer backbone may notably contribute to the required spatial adjustment for optimal interaction with the protein surface. By using oligoureas as α helix mimics, we designed a foldamer/peptide hybrid inhibitor of histone chaperone ASF1, a key regulator of chromatin dynamics. The crystal structure of its complex with ASF1 reveals a notable plasticity of the urea backbone, which adapts to the ASF1 surface to maintain the same binding interface. One additional benefit of generating ASF1 ligands with nonpeptide oligourea segments is the resistance to proteolysis in human plasma, which was highly improved compared to the cognate α-helical peptide.","lang":"eng"}],"intvolume":" 7","volume":7,"month":"03","publication_identifier":{"issn":["2375-2548"]},"acknowledgement":"We thank the Synchrotron SOLEIL, the European Synchrotron Radiation Facility (ESRF), and the French Infrastructure for Integrated Structural Biology (FRISBI) ANR-10-INBS-05. We are particularly grateful to A. Clavier and A. Campalans for help in setting up and performing the cell penetration assays. Funding: Research was funded by the French Centre National de Recherche Scientifique (CNRS), the Commissariat à l’Energie Atomique (CEA), University of Bordeaux, University Paris-Saclay, and the Synchrotron Soleil. The project was supported by the ANR 2007 BREAKABOUND (JC-07-216078), 2011 BIPBIP (ANR-10-BINF-0003), 2012 CHAPINHIB (ANR-12-BSV5-0022-01), 2015 CHIPSET (ANR-15-CE11-008-01), 2015 HIMPP2I (ANR-15-CE07-0010), and the program labeled by the ARC foundation 2016 PGA1*20160203953). M.B. was supported by Canceropole (Paris, France) and a grant for young researchers from La Ligue contre le Cancer. J.M. was supported by La Ligue contre le Cancer.","oa":1,"citation":{"mla":"Mbianda, Johanne, et al. “Optimal Anchoring of a Foldamer Inhibitor of ASF1 Histone Chaperone through Backbone Plasticity.” Science Advances, vol. 7, no. 12, eabd9153, American Association for the Advancement of Science, 2021, doi:10.1126/sciadv.abd9153.","ieee":"J. Mbianda et al., “Optimal anchoring of a foldamer inhibitor of ASF1 histone chaperone through backbone plasticity,” Science Advances, vol. 7, no. 12. American Association for the Advancement of Science, 2021.","ista":"Mbianda J, Bakail MM, André C, Moal G, Perrin ME, Pinna G, Guerois R, Becher F, Legrand P, Traoré S, Douat C, Guichard G, Ochsenbein F. 2021. Optimal anchoring of a foldamer inhibitor of ASF1 histone chaperone through backbone plasticity. Science Advances. 7(12), eabd9153.","chicago":"Mbianda, Johanne, May M Bakail, Christophe André, Gwenaëlle Moal, Marie E. Perrin, Guillaume Pinna, Raphaël Guerois, et al. “Optimal Anchoring of a Foldamer Inhibitor of ASF1 Histone Chaperone through Backbone Plasticity.” Science Advances. American Association for the Advancement of Science, 2021. https://doi.org/10.1126/sciadv.abd9153.","apa":"Mbianda, J., Bakail, M. M., André, C., Moal, G., Perrin, M. E., Pinna, G., … Ochsenbein, F. (2021). Optimal anchoring of a foldamer inhibitor of ASF1 histone chaperone through backbone plasticity. Science Advances. American Association for the Advancement of Science. https://doi.org/10.1126/sciadv.abd9153","ama":"Mbianda J, Bakail MM, André C, et al. Optimal anchoring of a foldamer inhibitor of ASF1 histone chaperone through backbone plasticity. Science Advances. 2021;7(12). doi:10.1126/sciadv.abd9153","short":"J. Mbianda, M.M. Bakail, C. André, G. Moal, M.E. Perrin, G. Pinna, R. Guerois, F. Becher, P. Legrand, S. Traoré, C. Douat, G. Guichard, F. Ochsenbein, Science Advances 7 (2021)."},"isi":1,"article_processing_charge":"No","author":[{"first_name":"Johanne","last_name":"Mbianda","full_name":"Mbianda, Johanne"},{"first_name":"May M","id":"FB3C3F8E-522F-11EA-B186-22963DDC885E","last_name":"Bakail","full_name":"Bakail, May M","orcid":"0000-0002-9592-1587"},{"first_name":"Christophe","last_name":"André","full_name":"André, Christophe"},{"first_name":"Gwenaëlle","last_name":"Moal","full_name":"Moal, Gwenaëlle"},{"full_name":"Perrin, Marie E.","last_name":"Perrin","first_name":"Marie E."},{"first_name":"Guillaume","last_name":"Pinna","full_name":"Pinna, Guillaume"},{"full_name":"Guerois, Raphaël","last_name":"Guerois","first_name":"Raphaël"},{"first_name":"Francois","last_name":"Becher","full_name":"Becher, Francois"},{"first_name":"Pierre","last_name":"Legrand","full_name":"Legrand, Pierre"},{"last_name":"Traoré","first_name":"Seydou","full_name":"Traoré, Seydou"},{"full_name":"Douat, Céline","first_name":"Céline","last_name":"Douat"},{"full_name":"Guichard, Gilles","first_name":"Gilles","last_name":"Guichard"},{"last_name":"Ochsenbein","first_name":"Françoise","full_name":"Ochsenbein, Françoise"}],"language":[{"iso":"eng"}]},{"doi":"10.48550/arXiv.2103.11389","ec_funded":1,"_id":"9281","publication_status":"submitted","article_number":"2103.11389","title":"Formal verification of Zagier's one-sentence proof","corr_author":"1","publication":"arXiv","oa_version":"Preprint","abstract":[{"text":"We comment on two formal proofs of Fermat's sum of two squares theorem, written using the Mathematical Components libraries of the Coq proof assistant. The first one follows Zagier's celebrated one-sentence proof; the second follows David Christopher's recent new proof relying on partition-theoretic arguments. Both formal proofs rely on a general property of involutions of finite sets, of independent interest. The proof technique consists for the most part of automating recurrent tasks (such as case distinctions and computations on natural numbers) via ad hoc tactics.","lang":"eng"}],"department":[{"_id":"LaEr"},{"_id":"ToHe"}],"main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/2103.11389"}],"related_material":{"record":[{"status":"public","relation":"other","id":"9946"}]},"date_updated":"2025-04-15T06:26:12Z","external_id":{"arxiv":["2103.11389"]},"day":"21","arxiv":1,"oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2021-03-23T05:38:48Z","status":"public","citation":{"short":"G. Dubach, F. Mühlböck, ArXiv (n.d.).","ama":"Dubach G, Mühlböck F. Formal verification of Zagier’s one-sentence proof. arXiv. doi:10.48550/arXiv.2103.11389","apa":"Dubach, G., & Mühlböck, F. (n.d.). Formal verification of Zagier’s one-sentence proof. arXiv. https://doi.org/10.48550/arXiv.2103.11389","chicago":"Dubach, Guillaume, and Fabian Mühlböck. “Formal Verification of Zagier’s One-Sentence Proof.” ArXiv, n.d. https://doi.org/10.48550/arXiv.2103.11389.","ista":"Dubach G, Mühlböck F. Formal verification of Zagier’s one-sentence proof. arXiv, 2103.11389.","mla":"Dubach, Guillaume, and Fabian Mühlböck. “Formal Verification of Zagier’s One-Sentence Proof.” ArXiv, 2103.11389, doi:10.48550/arXiv.2103.11389.","ieee":"G. Dubach and F. Mühlböck, “Formal verification of Zagier’s one-sentence proof,” arXiv. ."},"article_processing_charge":"No","date_published":"2021-03-21T00:00:00Z","author":[{"orcid":"0000-0001-6892-8137","full_name":"Dubach, Guillaume","last_name":"Dubach","id":"D5C6A458-10C4-11EA-ABF4-A4B43DDC885E","first_name":"Guillaume"},{"full_name":"Mühlböck, Fabian","orcid":"0000-0003-1548-0177","id":"6395C5F6-89DF-11E9-9C97-6BDFE5697425","first_name":"Fabian","last_name":"Mühlböck"}],"project":[{"_id":"260C2330-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","name":"ISTplus - Postdoctoral Fellowships","grant_number":"754411"}],"language":[{"iso":"eng"}],"year":"2021","month":"03","type":"preprint"},{"oa":1,"arxiv":1,"language":[{"iso":"eng"}],"author":[{"orcid":"0000-0002-2111-4846","full_name":"Nauman, Muhammad","last_name":"Nauman","first_name":"Muhammad","id":"32c21954-2022-11eb-9d5f-af9f93c24e71"},{"last_name":"Kiem","first_name":"Do Hoon","full_name":"Kiem, Do Hoon"},{"last_name":"Lee","first_name":"Sungmin","full_name":"Lee, Sungmin"},{"first_name":"Suhan","last_name":"Son","full_name":"Son, Suhan"},{"full_name":"Park, J-G","first_name":"J-G","last_name":"Park"},{"last_name":"Kang","first_name":"Woun","full_name":"Kang, Woun"},{"full_name":"Han, Myung Joon","last_name":"Han","first_name":"Myung Joon"},{"first_name":"Youn Jung","last_name":"Jo","full_name":"Jo, Youn Jung"}],"citation":{"ieee":"M. Nauman et al., “Complete mapping of magnetic anisotropy for prototype Ising van der Waals FePS3,” 2D Materials, vol. 8, no. 3. IOP Publishing, 2021.","mla":"Nauman, Muhammad, et al. “Complete Mapping of Magnetic Anisotropy for Prototype Ising van Der Waals FePS3.” 2D Materials, vol. 8, no. 3, 035011, IOP Publishing, 2021, doi:10.1088/2053-1583/abeed3.","ista":"Nauman M, Kiem DH, Lee S, Son S, Park J-G, Kang W, Han MJ, Jo YJ. 2021. Complete mapping of magnetic anisotropy for prototype Ising van der Waals FePS3. 2D Materials. 8(3), 035011.","chicago":"Nauman, Muhammad, Do Hoon Kiem, Sungmin Lee, Suhan Son, J-G Park, Woun Kang, Myung Joon Han, and Youn Jung Jo. “Complete Mapping of Magnetic Anisotropy for Prototype Ising van Der Waals FePS3.” 2D Materials. IOP Publishing, 2021. https://doi.org/10.1088/2053-1583/abeed3.","apa":"Nauman, M., Kiem, D. H., Lee, S., Son, S., Park, J.-G., Kang, W., … Jo, Y. J. (2021). Complete mapping of magnetic anisotropy for prototype Ising van der Waals FePS3. 2D Materials. IOP Publishing. https://doi.org/10.1088/2053-1583/abeed3","ama":"Nauman M, Kiem DH, Lee S, et al. Complete mapping of magnetic anisotropy for prototype Ising van der Waals FePS3. 2D Materials. 2021;8(3). doi:10.1088/2053-1583/abeed3","short":"M. Nauman, D.H. Kiem, S. Lee, S. Son, J.-G. Park, W. Kang, M.J. Han, Y.J. Jo, 2D Materials 8 (2021)."},"article_processing_charge":"No","month":"04","volume":8,"publication_identifier":{"issn":["2053-1583"]},"abstract":[{"lang":"eng","text":"Several Ising-type magnetic van der Waals (vdW) materials exhibit stable magnetic ground states. Despite these clear experimental demonstrations, a complete theoretical and microscopic understanding of their magnetic anisotropy is still lacking. In particular, the validity limit of identifying their one-dimensional (1-D) Ising nature has remained uninvestigated in a quantitative way. Here we performed the complete mapping of magnetic anisotropy for a prototypical Ising vdW magnet FePS3 for the first time. Combining torque magnetometry measurements with their magnetostatic model analysis and the relativistic density functional total energy calculations, we successfully constructed the three-dimensional (3-D) mappings of the magnetic anisotropy in terms of magnetic torque and energy. The results not only quantitatively confirm that the easy axis is perpendicular to the ab plane, but also reveal the anisotropies within the ab, ac, and bc planes. Our approach can be applied to the detailed quantitative study of magnetism in vdW materials."}],"intvolume":" 8","publication":"2D Materials","publication_status":"published","title":"Complete mapping of magnetic anisotropy for prototype Ising van der Waals FePS3","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/2103.09029"}],"day":"06","quality_controlled":"1","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","date_created":"2021-03-23T07:10:17Z","keyword":["Mechanical Engineering","General Materials Science","Mechanics of Materials","General Chemistry","Condensed Matter Physics"],"date_published":"2021-04-06T00:00:00Z","status":"public","issue":"3","year":"2021","publisher":"IOP Publishing","article_type":"original","type":"journal_article","doi":"10.1088/2053-1583/abeed3","oa_version":"Preprint","article_number":"035011","_id":"9282","department":[{"_id":"KiMo"}],"external_id":{"arxiv":["2103.09029"]},"extern":"1","date_updated":"2021-12-01T10:36:56Z"},{"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"doi":"10.7554/elife.65993","oa_version":"Published Version","file_date_updated":"2021-03-23T10:12:58Z","_id":"9283","file":[{"file_id":"9284","file_size":1390469,"file_name":"elife-65993-v2.pdf","creator":"bkavcic","date_updated":"2021-03-23T10:12:58Z","access_level":"open_access","checksum":"3c2f44058c2dd45a5a1027f09d263f8e","success":1,"content_type":"application/pdf","date_created":"2021-03-23T10:12:58Z","relation":"main_file"}],"article_number":"e65993","department":[{"_id":"GaTk"},{"_id":"CaGu"}],"external_id":{"pmid":["33683203"],"isi":["000631050900001"]},"related_material":{"record":[{"relation":"research_data","id":"8951","status":"public"}]},"date_updated":"2025-06-12T06:36:17Z","date_created":"2021-03-23T10:11:46Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","keyword":["Genetics and Molecular Biology"],"date_published":"2021-03-08T00:00:00Z","status":"public","pmid":1,"ddc":["570"],"year":"2021","publisher":"eLife Sciences Publications","type":"journal_article","article_type":"original","ec_funded":1,"abstract":[{"lang":"eng","text":"Gene expression levels are influenced by multiple coexisting molecular mechanisms. Some of these interactions such as those of transcription factors and promoters have been studied extensively. However, predicting phenotypes of gene regulatory networks (GRNs) remains a major challenge. Here, we use a well-defined synthetic GRN to study in Escherichia coli how network phenotypes depend on local genetic context, i.e. the genetic neighborhood of a transcription factor and its relative position. We show that one GRN with fixed topology can display not only quantitatively but also qualitatively different phenotypes, depending solely on the local genetic context of its components. Transcriptional read-through is the main molecular mechanism that places one transcriptional unit (TU) within two separate regulons without the need for complex regulatory sequences. We propose that relative order of individual TUs, with its potential for combinatorial complexity, plays an important role in shaping phenotypes of GRNs."}],"intvolume":" 10","publication":"eLife","corr_author":"1","title":"Local genetic context shapes the function of a gene regulatory network","publication_status":"published","has_accepted_license":"1","day":"08","quality_controlled":"1","oa":1,"acknowledgement":"We thank J Bollback, L Hurst, M Lagator, C Nizak, O Rivoire, M Savageau, G Tkacik, and B Vicozo\r\nfor helpful discussions; A Dolinar and A Greshnova for technical assistance; T Bollenbach for supplying the strain JW0336; C Rusnac, and members of the Guet lab for comments. The research leading to these results has received funding from the People Programme (Marie Curie Actions) of the European Union’s Seventh Framework Programme (FP7/2007-2013) under REA grant agreement n˚\r\n628377 (ANS) and an Austrian Science Fund (FWF) grant n˚ I 3901-B32 (CCG).","project":[{"grant_number":"628377","call_identifier":"FP7","name":"The Systems Biology of Transcriptional Read-Through in Bacteria: from Synthetic Networks to Genomic Studies","_id":"2517526A-B435-11E9-9278-68D0E5697425"},{"grant_number":"I03901","_id":"268BFA92-B435-11E9-9278-68D0E5697425","name":"Cybergenetic circuits to test composability of gene networks","call_identifier":"FWF"}],"language":[{"iso":"eng"}],"author":[{"orcid":"0000-0002-1391-8377","full_name":"Nagy-Staron, Anna A","last_name":"Nagy-Staron","first_name":"Anna A","id":"3ABC5BA6-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Kathrin","id":"3AEC8556-F248-11E8-B48F-1D18A9856A87","last_name":"Tomasek","full_name":"Tomasek, Kathrin","orcid":"0000-0003-3768-877X"},{"first_name":"Caroline","last_name":"Caruso Carter","full_name":"Caruso Carter, Caroline"},{"first_name":"Elisabeth","last_name":"Sonnleitner","full_name":"Sonnleitner, Elisabeth"},{"full_name":"Kavcic, Bor","orcid":"0000-0001-6041-254X","id":"350F91D2-F248-11E8-B48F-1D18A9856A87","first_name":"Bor","last_name":"Kavcic"},{"first_name":"Tiago","last_name":"Paixão","full_name":"Paixão, Tiago"},{"last_name":"Guet","id":"47F8433E-F248-11E8-B48F-1D18A9856A87","first_name":"Calin C","orcid":"0000-0001-6220-2052","full_name":"Guet, Calin C"}],"article_processing_charge":"Yes","isi":1,"citation":{"ama":"Nagy-Staron AA, Tomasek K, Caruso Carter C, et al. Local genetic context shapes the function of a gene regulatory network. eLife. 2021;10. doi:10.7554/elife.65993","apa":"Nagy-Staron, A. A., Tomasek, K., Caruso Carter, C., Sonnleitner, E., Kavcic, B., Paixão, T., & Guet, C. C. (2021). Local genetic context shapes the function of a gene regulatory network. ELife. eLife Sciences Publications. https://doi.org/10.7554/elife.65993","ista":"Nagy-Staron AA, Tomasek K, Caruso Carter C, Sonnleitner E, Kavcic B, Paixão T, Guet CC. 2021. Local genetic context shapes the function of a gene regulatory network. eLife. 10, e65993.","chicago":"Nagy-Staron, Anna A, Kathrin Tomasek, Caroline Caruso Carter, Elisabeth Sonnleitner, Bor Kavcic, Tiago Paixão, and Calin C Guet. “Local Genetic Context Shapes the Function of a Gene Regulatory Network.” ELife. eLife Sciences Publications, 2021. https://doi.org/10.7554/elife.65993.","short":"A.A. Nagy-Staron, K. Tomasek, C. Caruso Carter, E. Sonnleitner, B. Kavcic, T. Paixão, C.C. Guet, ELife 10 (2021).","ieee":"A. A. Nagy-Staron et al., “Local genetic context shapes the function of a gene regulatory network,” eLife, vol. 10. eLife Sciences Publications, 2021.","mla":"Nagy-Staron, Anna A., et al. “Local Genetic Context Shapes the Function of a Gene Regulatory Network.” ELife, vol. 10, e65993, eLife Sciences Publications, 2021, doi:10.7554/elife.65993."},"month":"03","scopus_import":"1","volume":10,"publication_identifier":{"issn":["2050-084X"]}},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2021-03-26T12:09:01Z","status":"public","date_published":"2021-03-17T00:00:00Z","year":"2021","ddc":["580"],"issue":"6","pmid":1,"article_type":"original","type":"journal_article","publisher":"Wiley","doi":"10.1111/nph.17349","_id":"9288","oa_version":"Published Version","department":[{"_id":"JiFr"}],"date_updated":"2026-06-18T19:44:45Z","external_id":{"isi":["000639552400001"],"pmid":["33728703"]},"oa":1,"page":"2275-2291","citation":{"ieee":"I. El Houari et al., “Seedling developmental defects upon blocking CINNAMATE-4-HYDROXYLASE are caused by perturbations in auxin transport,” New Phytologist, vol. 230, no. 6. Wiley, pp. 2275–2291, 2021.","mla":"El Houari, I., et al. “Seedling Developmental Defects upon Blocking CINNAMATE-4-HYDROXYLASE Are Caused by Perturbations in Auxin Transport.” New Phytologist, vol. 230, no. 6, Wiley, 2021, pp. 2275–91, doi:10.1111/nph.17349.","short":"I. El Houari, C. Van Beirs, H. Arents, H. Han, A. Chanoca, D. Opdenacker, J. Pollier, V. Storme, W. Steenackers, M. Quareshy, R. Napier, T. Beeckman, J. Friml, B. De Rybel, W. Boerjan, B. Vanholme, New Phytologist 230 (2021) 2275–2291.","chicago":"El Houari, I, C Van Beirs, HE Arents, Huibin Han, A Chanoca, D Opdenacker, J Pollier, et al. “Seedling Developmental Defects upon Blocking CINNAMATE-4-HYDROXYLASE Are Caused by Perturbations in Auxin Transport.” New Phytologist. Wiley, 2021. https://doi.org/10.1111/nph.17349.","ista":"El Houari I, Van Beirs C, Arents H, Han H, Chanoca A, Opdenacker D, Pollier J, Storme V, Steenackers W, Quareshy M, Napier R, Beeckman T, Friml J, De Rybel B, Boerjan W, Vanholme B. 2021. Seedling developmental defects upon blocking CINNAMATE-4-HYDROXYLASE are caused by perturbations in auxin transport. New Phytologist. 230(6), 2275–2291.","ama":"El Houari I, Van Beirs C, Arents H, et al. Seedling developmental defects upon blocking CINNAMATE-4-HYDROXYLASE are caused by perturbations in auxin transport. New Phytologist. 2021;230(6):2275-2291. doi:10.1111/nph.17349","apa":"El Houari, I., Van Beirs, C., Arents, H., Han, H., Chanoca, A., Opdenacker, D., … Vanholme, B. (2021). Seedling developmental defects upon blocking CINNAMATE-4-HYDROXYLASE are caused by perturbations in auxin transport. New Phytologist. Wiley. https://doi.org/10.1111/nph.17349"},"isi":1,"article_processing_charge":"No","author":[{"last_name":"El Houari","first_name":"I","full_name":"El Houari, I"},{"first_name":"C","last_name":"Van Beirs","full_name":"Van Beirs, C"},{"last_name":"Arents","first_name":"HE","full_name":"Arents, HE"},{"full_name":"Han, Huibin","last_name":"Han","first_name":"Huibin","id":"31435098-F248-11E8-B48F-1D18A9856A87"},{"first_name":"A","last_name":"Chanoca","full_name":"Chanoca, A"},{"last_name":"Opdenacker","first_name":"D","full_name":"Opdenacker, D"},{"full_name":"Pollier, J","first_name":"J","last_name":"Pollier"},{"first_name":"V","last_name":"Storme","full_name":"Storme, V"},{"full_name":"Steenackers, W","last_name":"Steenackers","first_name":"W"},{"full_name":"Quareshy, M","last_name":"Quareshy","first_name":"M"},{"last_name":"Napier","first_name":"R","full_name":"Napier, R"},{"first_name":"T","last_name":"Beeckman","full_name":"Beeckman, T"},{"first_name":"Jiří","id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml","full_name":"Friml, Jiří","orcid":"0000-0002-8302-7596"},{"full_name":"De Rybel, B","last_name":"De Rybel","first_name":"B"},{"last_name":"Boerjan","first_name":"W","full_name":"Boerjan, W"},{"full_name":"Vanholme, B","last_name":"Vanholme","first_name":"B"}],"language":[{"iso":"eng"}],"volume":230,"month":"03","scopus_import":"1","publication_identifier":{"eissn":["1469-8137"],"issn":["0028-646x"]},"title":"Seedling developmental defects upon blocking CINNAMATE-4-HYDROXYLASE are caused by perturbations in auxin transport","publication_status":"published","publication":"New Phytologist","abstract":[{"text":"• The phenylpropanoid pathway serves a central role in plant metabolism, providing numerous compounds involved in diverse physiological processes. Most carbon entering the pathway is incorporated into lignin. Although several phenylpropanoid pathway mutants show seedling growth arrest, the role for lignin in seedling growth and development is unexplored.\r\n• We use complementary pharmacological and genetic approaches to block CINNAMATE‐4‐HYDROXYLASE (C4H) functionality in Arabidopsis seedlings and a set of molecular and biochemical techniques to investigate the underlying phenotypes.\r\n• Blocking C4H resulted in reduced lateral rooting and increased adventitious rooting apically in the hypocotyl. These phenotypes coincided with an inhibition in auxin transport. The upstream accumulation in cis‐cinnamic acid was found to likely cause polar auxin transport inhibition. Conversely, a downstream depletion in lignin perturbed phloem‐mediated auxin transport. Restoring lignin deposition effectively reestablished phloem transport and, accordingly, auxin homeostasis.\r\n• Our results show that the accumulation of bioactive intermediates and depletion in lignin jointly cause the aberrant phenotypes upon blocking C4H, and demonstrate that proper deposition of lignin is essential for the establishment of auxin distribution in seedlings. Our data position the phenylpropanoid pathway and lignin in a new physiological framework, consolidating their importance in plant growth and development.","lang":"eng"}],"intvolume":" 230","main_file_link":[{"url":"https://biblio.ugent.be/publication/8703799/file/8703800.pdf","open_access":"1"}],"quality_controlled":"1","day":"17"},{"date_created":"2021-03-26T12:09:33Z","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","status":"public","date_published":"2021-03-10T00:00:00Z","ddc":["580"],"acknowledged_ssus":[{"_id":"Bio"}],"issue":"9","pmid":1,"year":"2021","type":"journal_article","article_type":"original","publisher":"Elsevier","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"doi":"10.1016/j.cub.2021.02.028","file_date_updated":"2021-04-01T10:53:42Z","oa_version":"Published Version","_id":"9290","file":[{"file_id":"9303","file_name":"2021_CurrentBiology_Glanc.pdf","file_size":4324371,"creator":"dernst","date_updated":"2021-04-01T10:53:42Z","access_level":"open_access","checksum":"b1723040ecfd8c81194185472eb62546","success":1,"content_type":"application/pdf","date_created":"2021-04-01T10:53:42Z","relation":"main_file"}],"department":[{"_id":"JiFr"}],"external_id":{"pmid":["33705718"],"isi":["000653077800004"]},"date_updated":"2025-04-14T07:45:00Z","oa":1,"acknowledgement":"We acknowledge Ben Scheres, Christian Luschnig, and Claus Schwechheimer for sharing published material. We thank Monika Hrtyan and Dorota Jaworska at IST Austria and Gerda Lamers and Ward de Winter at IBL Netherlands for technical assistance; Corinna Hartinger, Jakub Hajný, Lesia Rodriguez, Mingyue Li, and Lindy Abas for experimental support; and the Bioimaging Facility at IST Austria and the Bioimaging Core at VIB for imaging support. We are grateful to Christian Luschnig, Lindy Abas, and Roman Pleskot for valuable discussions. We also acknowledge the EMBO for supporting M.G. with a long-term fellowship ( ALTF 1005-2019 ) during the finalization and revision of this manuscript in the laboratory of B.D.R., and we thank R. Pierik for allowing K.V.G. to work on this manuscript during a postdoc in his laboratory at Utrecht University. This work was supported by grants from the European Research Council under the European Union’s Seventh Framework Programme (ERC grant agreements 742985 to J.F., 714055 to B.D.R., and 803048 to M.F.), the Austrian Science Fund (FWF; I 3630-B25 to J.F.), Chemical Sciences (partly) financed by the Dutch Research Council (NWO-CW TOP 700.58.301 to R.O.), the Dutch Research Council (NWO-VICI 865.17.002 to R. Pierik), Grants-in-Aid from the Ministry of Education, Culture, Sports, Science and Technology, Japan (KAKENHI grant 17K17595 to S.N.), the Ministry of Education, Youth and Sports of the Czech Republic (MŠMT project NPUI-LO1417 ), and a China Scholarship Council (to X.W.).","author":[{"last_name":"Glanc","first_name":"Matous","id":"1AE1EA24-02D0-11E9-9BAA-DAF4881429F2","orcid":"0000-0003-0619-7783","full_name":"Glanc, Matous"},{"full_name":"Van Gelderen, K","first_name":"K","last_name":"Van Gelderen"},{"id":"2EEE7A2A-F248-11E8-B48F-1D18A9856A87","first_name":"Lukas","last_name":"Hörmayer","full_name":"Hörmayer, Lukas","orcid":"0000-0001-8295-2926"},{"orcid":"0000-0002-0471-8285","full_name":"Tan, Shutang","last_name":"Tan","id":"2DE75584-F248-11E8-B48F-1D18A9856A87","first_name":"Shutang"},{"full_name":"Naramoto, S","first_name":"S","last_name":"Naramoto"},{"orcid":"0000-0001-7048-4627","full_name":"Zhang, Xixi","last_name":"Zhang","first_name":"Xixi","id":"61A66458-47E9-11EA-85BA-8AEAAF14E49A"},{"orcid":"0000-0003-2267-106X","full_name":"Domjan, David","last_name":"Domjan","id":"C684CD7A-257E-11EA-9B6F-D8588B4F947F","first_name":"David"},{"last_name":"Vcelarova","first_name":"L","full_name":"Vcelarova, L"},{"full_name":"Hauschild, Robert","orcid":"0000-0001-9843-3522","id":"4E01D6B4-F248-11E8-B48F-1D18A9856A87","first_name":"Robert","last_name":"Hauschild"},{"full_name":"Johnson, Alexander J","orcid":"0000-0002-2739-8843","id":"46A62C3A-F248-11E8-B48F-1D18A9856A87","first_name":"Alexander J","last_name":"Johnson"},{"full_name":"de Koning, E","first_name":"E","last_name":"de Koning"},{"full_name":"van Dop, M","last_name":"van Dop","first_name":"M"},{"last_name":"Rademacher","first_name":"E","full_name":"Rademacher, E"},{"full_name":"Janson, S","last_name":"Janson","first_name":"S"},{"first_name":"X","last_name":"Wei","full_name":"Wei, X"},{"full_name":"Molnar, Gergely","last_name":"Molnar","first_name":"Gergely","id":"34F1AF46-F248-11E8-B48F-1D18A9856A87"},{"orcid":"0000-0002-9767-8699","full_name":"Fendrych, Matyas","last_name":"Fendrych","first_name":"Matyas","id":"43905548-F248-11E8-B48F-1D18A9856A87"},{"full_name":"De Rybel, B","first_name":"B","last_name":"De Rybel"},{"full_name":"Offringa, R","first_name":"R","last_name":"Offringa"},{"orcid":"0000-0002-8302-7596","full_name":"Friml, Jiří","last_name":"Friml","first_name":"Jiří","id":"4159519E-F248-11E8-B48F-1D18A9856A87"}],"language":[{"iso":"eng"}],"project":[{"name":"Tracing Evolution of Auxin Transport and Polarity in Plants","call_identifier":"H2020","_id":"261099A6-B435-11E9-9278-68D0E5697425","grant_number":"742985"},{"name":"Molecular mechanisms of endocytic cargo recognition in plants","call_identifier":"FWF","_id":"26538374-B435-11E9-9278-68D0E5697425","grant_number":"I03630"}],"page":"1918-1930","isi":1,"citation":{"ieee":"M. Glanc et al., “AGC kinases and MAB4/MEL proteins maintain PIN polarity by limiting lateral diffusion in plant cells,” Current Biology, vol. 31, no. 9. Elsevier, pp. 1918–1930, 2021.","mla":"Glanc, Matous, et al. “AGC Kinases and MAB4/MEL Proteins Maintain PIN Polarity by Limiting Lateral Diffusion in Plant Cells.” Current Biology, vol. 31, no. 9, Elsevier, 2021, pp. 1918–30, doi:10.1016/j.cub.2021.02.028.","apa":"Glanc, M., Van Gelderen, K., Hörmayer, L., Tan, S., Naramoto, S., Zhang, X., … Friml, J. (2021). AGC kinases and MAB4/MEL proteins maintain PIN polarity by limiting lateral diffusion in plant cells. Current Biology. Elsevier. https://doi.org/10.1016/j.cub.2021.02.028","ama":"Glanc M, Van Gelderen K, Hörmayer L, et al. AGC kinases and MAB4/MEL proteins maintain PIN polarity by limiting lateral diffusion in plant cells. Current Biology. 2021;31(9):1918-1930. doi:10.1016/j.cub.2021.02.028","ista":"Glanc M, Van Gelderen K, Hörmayer L, Tan S, Naramoto S, Zhang X, Domjan D, Vcelarova L, Hauschild R, Johnson AJ, de Koning E, van Dop M, Rademacher E, Janson S, Wei X, Molnar G, Fendrych M, De Rybel B, Offringa R, Friml J. 2021. AGC kinases and MAB4/MEL proteins maintain PIN polarity by limiting lateral diffusion in plant cells. Current Biology. 31(9), 1918–1930.","chicago":"Glanc, Matous, K Van Gelderen, Lukas Hörmayer, Shutang Tan, S Naramoto, Xixi Zhang, David Domjan, et al. “AGC Kinases and MAB4/MEL Proteins Maintain PIN Polarity by Limiting Lateral Diffusion in Plant Cells.” Current Biology. Elsevier, 2021. https://doi.org/10.1016/j.cub.2021.02.028.","short":"M. Glanc, K. Van Gelderen, L. Hörmayer, S. Tan, S. Naramoto, X. Zhang, D. Domjan, L. Vcelarova, R. Hauschild, A.J. Johnson, E. de Koning, M. van Dop, E. Rademacher, S. Janson, X. Wei, G. Molnar, M. Fendrych, B. De Rybel, R. Offringa, J. Friml, Current Biology 31 (2021) 1918–1930."},"article_processing_charge":"No","volume":31,"scopus_import":"1","month":"03","publication_identifier":{"eissn":["1879-0445"],"issn":["0960-9822"]},"ec_funded":1,"publication":"Current Biology","intvolume":" 31","abstract":[{"text":"Polar subcellular localization of the PIN exporters of the phytohormone auxin is a key determinant of directional, intercellular auxin transport and thus a central topic of both plant cell and developmental biology. Arabidopsis mutants lacking PID, a kinase that phosphorylates PINs, or the MAB4/MEL proteins of unknown molecular function display PIN polarity defects and phenocopy pin mutants, but mechanistic insights into how these factors convey PIN polarity are missing. Here, by combining protein biochemistry with quantitative live-cell imaging, we demonstrate that PINs, MAB4/MELs, and AGC kinases interact in the same complex at the plasma membrane. MAB4/MELs are recruited to the plasma membrane by the PINs and in concert with the AGC kinases maintain PIN polarity through limiting lateral diffusion-based escape of PINs from the polar domain. The PIN-MAB4/MEL-PID protein complex has self-reinforcing properties thanks to positive feedback between AGC kinase-mediated PIN phosphorylation and MAB4/MEL recruitment. We thus uncover the molecular mechanism by which AGC kinases and MAB4/MEL proteins regulate PIN localization and plant development.","lang":"eng"}],"has_accepted_license":"1","corr_author":"1","publication_status":"published","title":"AGC kinases and MAB4/MEL proteins maintain PIN polarity by limiting lateral diffusion in plant cells","day":"10","quality_controlled":"1"},{"author":[{"id":"38DB5788-F248-11E8-B48F-1D18A9856A87","first_name":"Georgios","last_name":"Katsaros","full_name":"Katsaros, Georgios","orcid":"0000-0001-8342-202X"}],"citation":{"mla":"Katsaros, Georgios. Raw Transport Data for: Enhancement of Proximity Induced Superconductivity in Planar Germanium. Institute of Science and Technology Austria, 2021, doi:10.15479/AT:ISTA:9291.","ieee":"G. Katsaros, “Raw transport data for: Enhancement of proximity induced superconductivity in planar germanium.” Institute of Science and Technology Austria, 2021.","short":"G. Katsaros, (2021).","chicago":"Katsaros, Georgios. “Raw Transport Data for: Enhancement of Proximity Induced Superconductivity in Planar Germanium.” Institute of Science and Technology Austria, 2021. https://doi.org/10.15479/AT:ISTA:9291.","ista":"Katsaros G. 2021. Raw transport data for: Enhancement of proximity induced superconductivity in planar germanium, Institute of Science and Technology Austria, 10.15479/AT:ISTA:9291.","ama":"Katsaros G. Raw transport data for: Enhancement of proximity induced superconductivity in planar germanium. 2021. doi:10.15479/AT:ISTA:9291","apa":"Katsaros, G. (2021). Raw transport data for: Enhancement of proximity induced superconductivity in planar germanium. Institute of Science and Technology Austria. https://doi.org/10.15479/AT:ISTA:9291"},"article_processing_charge":"No","date_published":"2021-03-29T00:00:00Z","status":"public","date_created":"2021-03-27T13:47:49Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"publisher":"Institute of Science and Technology Austria","type":"research_data","ddc":["530"],"month":"03","license":"https://creativecommons.org/publicdomain/zero/1.0/","year":"2021","oa_version":"Published Version","abstract":[{"text":"This .zip File contains the transport data for figures presented in the main text and supplementary material of \"Enhancement of Proximity Induced Superconductivity in Planar Germanium\" by K. Aggarwal, et. al. \r\nThe measurements were done using Labber Software and the data is stored in the hdf5 file format. The files can be opened using either the Labber Log Browser (https://labber.org/overview/) or Labber Python API (http://labber.org/online-doc/api/LogFile.html).","lang":"eng"}],"file_date_updated":"2021-04-01T07:52:56Z","file":[{"access_level":"open_access","date_updated":"2021-03-27T13:46:17Z","checksum":"635df3c08fc13c3dac008cd421aefbe4","file_name":"Raw Data- Enhancement of Superconductivity in a Planar Ge hole gas.zip","file_size":10616071,"file_id":"9292","creator":"gkatsaro","relation":"main_file","date_created":"2021-03-27T13:46:17Z","content_type":"application/x-zip-compressed","success":1},{"date_created":"2021-04-01T07:52:56Z","content_type":"text/plain","success":1,"relation":"main_file","file_size":470,"file_name":"README.txt","file_id":"9302","creator":"dernst","access_level":"open_access","date_updated":"2021-04-01T07:52:56Z","checksum":"12b3ca69ae7509a346711baae0b02a75"}],"_id":"9291","title":"Raw transport data for: Enhancement of proximity induced superconductivity in planar germanium","has_accepted_license":"1","tmp":{"short":"CC0 (1.0)","image":"/images/cc_0.png","legal_code_url":"https://creativecommons.org/publicdomain/zero/1.0/legalcode","name":"Creative Commons Public Domain Dedication (CC0 1.0)"},"doi":"10.15479/AT:ISTA:9291","day":"29","date_updated":"2024-02-21T12:37:14Z","department":[{"_id":"GeKa"}]},{"doi":"10.1016/j.devcel.2021.03.002","oa_version":"Published Version","_id":"9294","department":[{"_id":"MiSi"}],"external_id":{"isi":["000631681200004"],"pmid":["33756118"]},"date_updated":"2026-06-18T19:45:10Z","date_created":"2021-03-28T22:01:41Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2021-03-22T00:00:00Z","status":"public","pmid":1,"issue":"6","ddc":["570"],"year":"2021","publisher":"Elsevier","article_type":"original","type":"journal_article","abstract":[{"lang":"eng","text":"In this issue of Developmental Cell, Doyle and colleagues identify periodic anterior contraction as a characteristic feature of fibroblasts and mesenchymal cancer cells embedded in 3D collagen gels. This contractile mechanism generates a matrix prestrain required for crawling in fibrous 3D environments."}],"intvolume":" 56","publication":"Developmental Cell","publication_status":"published","title":"Engaging the front wheels to drive through fibrous terrain","corr_author":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1016/j.devcel.2021.03.002"}],"day":"22","quality_controlled":"1","oa":1,"language":[{"iso":"eng"}],"author":[{"id":"397A88EE-F248-11E8-B48F-1D18A9856A87","first_name":"Florian R","last_name":"Gärtner","full_name":"Gärtner, Florian R","orcid":"0000-0001-6120-3723"},{"first_name":"Michael K","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87","last_name":"Sixt","full_name":"Sixt, Michael K","orcid":"0000-0002-6620-9179"}],"citation":{"ieee":"F. R. Gärtner and M. K. Sixt, “Engaging the front wheels to drive through fibrous terrain,” Developmental Cell, vol. 56, no. 6. Elsevier, pp. 723–725, 2021.","mla":"Gärtner, Florian R., and Michael K. Sixt. “Engaging the Front Wheels to Drive through Fibrous Terrain.” Developmental Cell, vol. 56, no. 6, Elsevier, 2021, pp. 723–25, doi:10.1016/j.devcel.2021.03.002.","short":"F.R. Gärtner, M.K. Sixt, Developmental Cell 56 (2021) 723–725.","ama":"Gärtner FR, Sixt MK. Engaging the front wheels to drive through fibrous terrain. Developmental Cell. 2021;56(6):723-725. doi:10.1016/j.devcel.2021.03.002","apa":"Gärtner, F. R., & Sixt, M. K. (2021). Engaging the front wheels to drive through fibrous terrain. Developmental Cell. Elsevier. https://doi.org/10.1016/j.devcel.2021.03.002","chicago":"Gärtner, Florian R, and Michael K Sixt. “Engaging the Front Wheels to Drive through Fibrous Terrain.” Developmental Cell. Elsevier, 2021. https://doi.org/10.1016/j.devcel.2021.03.002.","ista":"Gärtner FR, Sixt MK. 2021. Engaging the front wheels to drive through fibrous terrain. Developmental Cell. 56(6), 723–725."},"isi":1,"article_processing_charge":"No","page":"723-725","month":"03","scopus_import":"1","volume":56,"publication_identifier":{"issn":["1534-5807"],"eissn":["1878-1551"]}},{"doi":"10.1002/jgt.22665","_id":"9295","oa_version":"Preprint","department":[{"_id":"UlWa"}],"date_updated":"2025-04-14T07:43:51Z","external_id":{"arxiv":["2002.02287"],"isi":["000631693200001"]},"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","date_created":"2021-03-28T22:01:41Z","date_published":"2021-03-23T00:00:00Z","status":"public","year":"2021","issue":"3","publisher":"Wiley","type":"journal_article","article_type":"original","ec_funded":1,"publication_status":"published","title":"Drawings of complete graphs in the projective plane","abstract":[{"text":"Hill's Conjecture states that the crossing number cr(𝐾𝑛) of the complete graph 𝐾𝑛 in the plane (equivalently, the sphere) is 14⌊𝑛2⌋⌊𝑛−12⌋⌊𝑛−22⌋⌊𝑛−32⌋=𝑛4/64+𝑂(𝑛3) . Moon proved that the expected number of crossings in a spherical drawing in which the points are randomly distributed and joined by geodesics is precisely 𝑛4/64+𝑂(𝑛3) , thus matching asymptotically the conjectured value of cr(𝐾𝑛) . Let cr𝑃(𝐺) denote the crossing number of a graph 𝐺 in the projective plane. Recently, Elkies proved that the expected number of crossings in a naturally defined random projective plane drawing of 𝐾𝑛 is (𝑛4/8𝜋2)+𝑂(𝑛3) . In analogy with the relation of Moon's result to Hill's conjecture, Elkies asked if lim𝑛→∞ cr𝑃(𝐾𝑛)/𝑛4=1/8𝜋2 . We construct drawings of 𝐾𝑛 in the projective plane that disprove this.","lang":"eng"}],"intvolume":" 97","publication":"Journal of Graph Theory","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/2002.02287"}],"quality_controlled":"1","day":"23","acknowledgement":"We thank two reviewers for their corrections and suggestions on the original version of this\r\npaper. This project has received funding from NSERC Grant 50503-10940-500 and from the European Union’s Horizon 2020 research and innovation programme under the Marie SkłodowskaCurie grant agreement No 754411, IST, Klosterneuburg, Austria.","arxiv":1,"oa":1,"article_processing_charge":"No","isi":1,"citation":{"short":"A.M. Arroyo Guevara, D. Mcquillan, R.B. Richter, G. Salazar, M. Sullivan, Journal of Graph Theory 97 (2021) 426–440.","ista":"Arroyo Guevara AM, Mcquillan D, Richter RB, Salazar G, Sullivan M. 2021. Drawings of complete graphs in the projective plane. Journal of Graph Theory. 97(3), 426–440.","chicago":"Arroyo Guevara, Alan M, Dan Mcquillan, R. Bruce Richter, Gelasio Salazar, and Matthew Sullivan. “Drawings of Complete Graphs in the Projective Plane.” Journal of Graph Theory. Wiley, 2021. https://doi.org/10.1002/jgt.22665.","ama":"Arroyo Guevara AM, Mcquillan D, Richter RB, Salazar G, Sullivan M. Drawings of complete graphs in the projective plane. Journal of Graph Theory. 2021;97(3):426-440. doi:10.1002/jgt.22665","apa":"Arroyo Guevara, A. M., Mcquillan, D., Richter, R. B., Salazar, G., & Sullivan, M. (2021). Drawings of complete graphs in the projective plane. Journal of Graph Theory. Wiley. https://doi.org/10.1002/jgt.22665","mla":"Arroyo Guevara, Alan M., et al. “Drawings of Complete Graphs in the Projective Plane.” Journal of Graph Theory, vol. 97, no. 3, Wiley, 2021, pp. 426–40, doi:10.1002/jgt.22665.","ieee":"A. M. Arroyo Guevara, D. Mcquillan, R. B. Richter, G. Salazar, and M. Sullivan, “Drawings of complete graphs in the projective plane,” Journal of Graph Theory, vol. 97, no. 3. Wiley, pp. 426–440, 2021."},"page":"426-440","project":[{"_id":"260C2330-B435-11E9-9278-68D0E5697425","name":"ISTplus - Postdoctoral Fellowships","call_identifier":"H2020","grant_number":"754411"}],"language":[{"iso":"eng"}],"author":[{"orcid":"0000-0003-2401-8670","full_name":"Arroyo Guevara, Alan M","last_name":"Arroyo Guevara","id":"3207FDC6-F248-11E8-B48F-1D18A9856A87","first_name":"Alan M"},{"full_name":"Mcquillan, Dan","first_name":"Dan","last_name":"Mcquillan"},{"last_name":"Richter","first_name":"R. Bruce","full_name":"Richter, R. Bruce"},{"full_name":"Salazar, Gelasio","last_name":"Salazar","first_name":"Gelasio"},{"first_name":"Matthew","last_name":"Sullivan","full_name":"Sullivan, Matthew"}],"month":"03","scopus_import":"1","volume":97,"publication_identifier":{"issn":["0364-9024"],"eissn":["1097-0118"]}},{"oa":1,"arxiv":1,"acknowledgement":"A.A. funded by the Marie Skłodowska-Curie grant agreement No. 754411. Z.M. partially funded by Wittgenstein Prize, Austrian Science Fund (FWF), grant no. Z 342-N31. I.P., D.P., and B.V. partially supported by FWF within the collaborative DACH project Arrangements and Drawings as FWF project I 3340-N35. A.P. supported by a Schrödinger fellowship of the FWF: J-3847-N35. J.T. partially supported by ERC Start grant no. (279307: Graph Games), FWF grant no. P23499-N23 and S11407-N23 (RiSE).","author":[{"full_name":"Aichholzer, Oswin","last_name":"Aichholzer","first_name":"Oswin"},{"last_name":"Arroyo Guevara","id":"3207FDC6-F248-11E8-B48F-1D18A9856A87","first_name":"Alan M","orcid":"0000-0003-2401-8670","full_name":"Arroyo Guevara, Alan M"},{"orcid":"0000-0002-6660-1322","full_name":"Masárová, Zuzana","last_name":"Masárová","first_name":"Zuzana","id":"45CFE238-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Irene","last_name":"Parada","full_name":"Parada, Irene"},{"full_name":"Perz, Daniel","first_name":"Daniel","last_name":"Perz"},{"full_name":"Pilz, Alexander","last_name":"Pilz","first_name":"Alexander"},{"orcid":"0000-0002-1097-9684","full_name":"Tkadlec, Josef","last_name":"Tkadlec","first_name":"Josef","id":"3F24CCC8-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Vogtenhuber, Birgit","last_name":"Vogtenhuber","first_name":"Birgit"}],"project":[{"grant_number":"754411","_id":"260C2330-B435-11E9-9278-68D0E5697425","name":"ISTplus - Postdoctoral Fellowships","call_identifier":"H2020"},{"grant_number":"Z00342","name":"Mathematics, Computer Science","call_identifier":"FWF","_id":"268116B8-B435-11E9-9278-68D0E5697425"},{"_id":"2581B60A-B435-11E9-9278-68D0E5697425","name":"Quantitative Graph Games: Theory and Applications","call_identifier":"FP7","grant_number":"279307"},{"grant_number":"P 23499-N23","name":"Modern Graph Algorithmic Techniques in Formal Verification","call_identifier":"FWF","_id":"2584A770-B435-11E9-9278-68D0E5697425"},{"_id":"25863FF4-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","name":"Game Theory","grant_number":"S11407"}],"language":[{"iso":"eng"}],"page":"221-233","article_processing_charge":"No","isi":1,"citation":{"short":"O. Aichholzer, A.M. Arroyo Guevara, Z. Masárová, I. Parada, D. Perz, A. Pilz, J. Tkadlec, B. Vogtenhuber, in:, 15th International Conference on Algorithms and Computation, Springer Nature, 2021, pp. 221–233.","chicago":"Aichholzer, Oswin, Alan M Arroyo Guevara, Zuzana Masárová, Irene Parada, Daniel Perz, Alexander Pilz, Josef Tkadlec, and Birgit Vogtenhuber. “On Compatible Matchings.” In 15th International Conference on Algorithms and Computation, 12635:221–33. Springer Nature, 2021. https://doi.org/10.1007/978-3-030-68211-8_18.","ista":"Aichholzer O, Arroyo Guevara AM, Masárová Z, Parada I, Perz D, Pilz A, Tkadlec J, Vogtenhuber B. 2021. On compatible matchings. 15th International Conference on Algorithms and Computation. WALCOM: Algorithms and Computation, LNCS, vol. 12635, 221–233.","ama":"Aichholzer O, Arroyo Guevara AM, Masárová Z, et al. On compatible matchings. In: 15th International Conference on Algorithms and Computation. Vol 12635. Springer Nature; 2021:221-233. doi:10.1007/978-3-030-68211-8_18","apa":"Aichholzer, O., Arroyo Guevara, A. M., Masárová, Z., Parada, I., Perz, D., Pilz, A., … Vogtenhuber, B. (2021). On compatible matchings. In 15th International Conference on Algorithms and Computation (Vol. 12635, pp. 221–233). Yangon, Myanmar: Springer Nature. https://doi.org/10.1007/978-3-030-68211-8_18","mla":"Aichholzer, Oswin, et al. “On Compatible Matchings.” 15th International Conference on Algorithms and Computation, vol. 12635, Springer Nature, 2021, pp. 221–33, doi:10.1007/978-3-030-68211-8_18.","ieee":"O. Aichholzer et al., “On compatible matchings,” in 15th International Conference on Algorithms and Computation, Yangon, Myanmar, 2021, vol. 12635, pp. 221–233."},"volume":12635,"month":"02","scopus_import":"1","publication_identifier":{"eisbn":["9783030682118"],"issn":["0302-9743"],"isbn":["9783030682101"],"eissn":["1611-3349"]},"ec_funded":1,"publication":"15th International Conference on Algorithms and Computation","intvolume":" 12635","abstract":[{"lang":"eng","text":" matching is compatible to two or more labeled point sets of size n with labels {1,…,n} if its straight-line drawing on each of these point sets is crossing-free. We study the maximum number of edges in a matching compatible to two or more labeled point sets in general position in the plane. We show that for any two labeled convex sets of n points there exists a compatible matching with ⌊2n−−√⌋ edges. More generally, for any ℓ labeled point sets we construct compatible matchings of size Ω(n1/ℓ) . As a corresponding upper bound, we use probabilistic arguments to show that for any ℓ given sets of n points there exists a labeling of each set such that the largest compatible matching has O(n2/(ℓ+1)) edges. Finally, we show that Θ(logn) copies of any set of n points are necessary and sufficient for the existence of a labeling such that any compatible matching consists only of a single edge."}],"publication_status":"published","title":"On compatible matchings","main_file_link":[{"url":"https://arxiv.org/abs/2101.03928","open_access":"1"}],"day":"16","quality_controlled":"1","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","date_created":"2021-03-28T22:01:41Z","status":"public","date_published":"2021-02-16T00:00:00Z","year":"2021","conference":{"location":"Yangon, Myanmar","end_date":"2021-03-02","start_date":"2021-02-28","name":"WALCOM: Algorithms and Computation"},"type":"conference","publisher":"Springer Nature","doi":"10.1007/978-3-030-68211-8_18","oa_version":"Preprint","alternative_title":["LNCS"],"_id":"9296","department":[{"_id":"UlWa"},{"_id":"HeEd"},{"_id":"KrCh"}],"external_id":{"arxiv":["2101.03928"],"isi":["001435069600018"]},"related_material":{"record":[{"relation":"later_version","id":"11938","status":"public"}]},"date_updated":"2026-04-16T09:18:21Z"},{"oa_version":"Preprint","article_number":"A65","_id":"9297","doi":"10.1017/jfm.2021.89","external_id":{"isi":["000629677500001"],"arxiv":["2008.08851"]},"date_updated":"2023-08-07T14:30:11Z","department":[{"_id":"BjHo"}],"status":"public","date_published":"2021-03-17T00:00:00Z","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","date_created":"2021-03-28T22:01:42Z","type":"journal_article","article_type":"original","publisher":"Cambridge University Press","year":"2021","publication":"Journal of Fluid Mechanics","intvolume":" 915","abstract":[{"text":"We report the results of an experimental investigation into the decay of turbulence in plane Couette–Poiseuille flow using ‘quench’ experiments where the flow laminarises after a sudden reduction in Reynolds number Re. Specifically, we study the velocity field in the streamwise–spanwise plane. We show that the spanwise velocity containing rolls decays faster than the streamwise velocity, which displays elongated regions of higher or lower velocity called streaks. At final Reynolds numbers above 425, the decay of streaks displays two stages: first a slow decay when rolls are present and secondly a more rapid decay of streaks alone. The difference in behaviour results from the regeneration of streaks by rolls, called the lift-up effect. We define the turbulent fraction as the portion of the flow containing turbulence and this is estimated by thresholding the spanwise velocity component. It decreases linearly with time in the whole range of final Re. The corresponding decay slope increases linearly with final Re. The extrapolated value at which this decay slope vanishes is Reaz≈656±10, close to Reg≈670 at which turbulence is self-sustained. The decay of the energy computed from the spanwise velocity component is found to be exponential. The corresponding decay rate increases linearly with Re, with an extrapolated vanishing value at ReAz≈688±10. This value is also close to the value at which the turbulence is self-sustained, showing that valuable information on the transition can be obtained over a wide range of Re.","lang":"eng"}],"publication_status":"published","title":"Decay of streaks and rolls in plane Couette-Poiseuille flow","day":"17","quality_controlled":"1","main_file_link":[{"url":"https://arxiv.org/abs/2008.08851","open_access":"1"}],"author":[{"first_name":"T.","last_name":"Liu","full_name":"Liu, T."},{"full_name":"Semin, B.","first_name":"B.","last_name":"Semin"},{"last_name":"Klotz","id":"2C9AF1C2-F248-11E8-B48F-1D18A9856A87","first_name":"Lukasz","orcid":"0000-0003-1740-7635","full_name":"Klotz, Lukasz"},{"last_name":"Godoy-Diana","first_name":"R.","full_name":"Godoy-Diana, R."},{"full_name":"Wesfreid, J. E.","last_name":"Wesfreid","first_name":"J. E."},{"last_name":"Mullin","first_name":"T.","full_name":"Mullin, T."}],"language":[{"iso":"eng"}],"isi":1,"citation":{"short":"T. Liu, B. Semin, L. Klotz, R. Godoy-Diana, J.E. Wesfreid, T. Mullin, Journal of Fluid Mechanics 915 (2021).","ama":"Liu T, Semin B, Klotz L, Godoy-Diana R, Wesfreid JE, Mullin T. Decay of streaks and rolls in plane Couette-Poiseuille flow. Journal of Fluid Mechanics. 2021;915. doi:10.1017/jfm.2021.89","apa":"Liu, T., Semin, B., Klotz, L., Godoy-Diana, R., Wesfreid, J. E., & Mullin, T. (2021). Decay of streaks and rolls in plane Couette-Poiseuille flow. Journal of Fluid Mechanics. Cambridge University Press. https://doi.org/10.1017/jfm.2021.89","chicago":"Liu, T., B. Semin, Lukasz Klotz, R. Godoy-Diana, J. E. Wesfreid, and T. Mullin. “Decay of Streaks and Rolls in Plane Couette-Poiseuille Flow.” Journal of Fluid Mechanics. Cambridge University Press, 2021. https://doi.org/10.1017/jfm.2021.89.","ista":"Liu T, Semin B, Klotz L, Godoy-Diana R, Wesfreid JE, Mullin T. 2021. Decay of streaks and rolls in plane Couette-Poiseuille flow. Journal of Fluid Mechanics. 915, A65.","ieee":"T. Liu, B. Semin, L. Klotz, R. Godoy-Diana, J. E. Wesfreid, and T. Mullin, “Decay of streaks and rolls in plane Couette-Poiseuille flow,” Journal of Fluid Mechanics, vol. 915. Cambridge University Press, 2021.","mla":"Liu, T., et al. “Decay of Streaks and Rolls in Plane Couette-Poiseuille Flow.” Journal of Fluid Mechanics, vol. 915, A65, Cambridge University Press, 2021, doi:10.1017/jfm.2021.89."},"article_processing_charge":"No","oa":1,"arxiv":1,"acknowledgement":"We gratefully acknowledge Joran Rolland, Yohann Duguet, Romain Monchaux, S´ebastien Gom´e, Laurette Tuckerman, Dwight Barkley, Olivier Dauchot and Sabine Bottin for fruitful discussions. We thank Xavier Benoit-Gonin, Amaury Fourgeaud, Thierry Darnige, Olivier Brouard and Justine Laurent for technical help. This work has benefited from the ANR TransFlow, and by starting grants obtained by B.S. from CNRS (INSIS) and ESPCI. T.M. was\r\nsupported by a Joliot visiting professorship grant from ESPCI.","publication_identifier":{"eissn":["1469-7645"],"issn":["0022-1120"]},"volume":915,"month":"03","scopus_import":"1"},{"publication_identifier":{"issn":["0027-8424"],"eissn":["1091-6490"]},"volume":118,"scopus_import":"1","month":"04","author":[{"last_name":"Prehal","first_name":"Christian","full_name":"Prehal, Christian"},{"full_name":"Samojlov, Aleksej","first_name":"Aleksej","last_name":"Samojlov"},{"full_name":"Nachtnebel, Manfred","last_name":"Nachtnebel","first_name":"Manfred"},{"orcid":"0000-0001-6206-4200","full_name":"Lovicar, Ludek","last_name":"Lovicar","first_name":"Ludek","id":"36DB3A20-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Kriechbaum","first_name":"Manfred","full_name":"Kriechbaum, Manfred"},{"full_name":"Amenitsch, Heinz","first_name":"Heinz","last_name":"Amenitsch"},{"orcid":"0000-0003-2902-5319","full_name":"Freunberger, Stefan Alexander","last_name":"Freunberger","first_name":"Stefan Alexander","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425"}],"language":[{"iso":"eng"}],"citation":{"ieee":"C. Prehal et al., “In situ small-angle X-ray scattering reveals solution phase discharge of Li–O2 batteries with weakly solvating electrolytes,” Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 14. National Academy of Sciences, 2021.","mla":"Prehal, Christian, et al. “In Situ Small-Angle X-Ray Scattering Reveals Solution Phase Discharge of Li–O2 Batteries with Weakly Solvating Electrolytes.” Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 14, e2021893118, National Academy of Sciences, 2021, doi:10.1073/pnas.2021893118.","chicago":"Prehal, Christian, Aleksej Samojlov, Manfred Nachtnebel, Ludek Lovicar, Manfred Kriechbaum, Heinz Amenitsch, and Stefan Alexander Freunberger. “In Situ Small-Angle X-Ray Scattering Reveals Solution Phase Discharge of Li–O2 Batteries with Weakly Solvating Electrolytes.” Proceedings of the National Academy of Sciences of the United States of America. National Academy of Sciences, 2021. https://doi.org/10.1073/pnas.2021893118.","ista":"Prehal C, Samojlov A, Nachtnebel M, Lovicar L, Kriechbaum M, Amenitsch H, Freunberger SA. 2021. In situ small-angle X-ray scattering reveals solution phase discharge of Li–O2 batteries with weakly solvating electrolytes. Proceedings of the National Academy of Sciences of the United States of America. 118(14), e2021893118.","apa":"Prehal, C., Samojlov, A., Nachtnebel, M., Lovicar, L., Kriechbaum, M., Amenitsch, H., & Freunberger, S. A. (2021). In situ small-angle X-ray scattering reveals solution phase discharge of Li–O2 batteries with weakly solvating electrolytes. Proceedings of the National Academy of Sciences of the United States of America. National Academy of Sciences. https://doi.org/10.1073/pnas.2021893118","ama":"Prehal C, Samojlov A, Nachtnebel M, et al. In situ small-angle X-ray scattering reveals solution phase discharge of Li–O2 batteries with weakly solvating electrolytes. Proceedings of the National Academy of Sciences of the United States of America. 2021;118(14). doi:10.1073/pnas.2021893118","short":"C. Prehal, A. Samojlov, M. Nachtnebel, L. Lovicar, M. Kriechbaum, H. Amenitsch, S.A. Freunberger, Proceedings of the National Academy of Sciences of the United States of America 118 (2021)."},"isi":1,"article_processing_charge":"No","oa":1,"acknowledgement":"S.A.F. and C.P. are indebted to the European Research Council under the European Union's Horizon 2020 research and innovation program (Grant Agreement No. 636069), the Austrian Federal Ministry of Science, Research and Economy, and the Austrian Research Promotion Agency (Grant No. 845364). We acknowledge A. Zankel and H. Schroettner for support with SEM measurements. C.P. thanks N. Kostoglou, C. Koczwara, M. Hartmann, and M. Burian for discussions on gas sorption analysis, C++ programming, Monte Carlo modeling, and in situ SAXS experiments, respectively. We thank S. Stadlbauer for help with Karl Fischer titration, R. Riccò for gas sorption measurements, and acknowledge Graz University of Technology for support through the Lead Project LP-03. Likewise, the use of SOMAPP Lab, a core facility supported by the Austrian Federal Ministry of Education, Science and Research, the Graz University of Technology, the University of Graz, and Anton Paar GmbH is acknowledged. S.A.F. is indebted to Institute of Science and Technology Austria (IST Austria) for support. This research was supported by the Scientific Service Units of IST Austria through resources provided by the Electron Microscopy Facility.","day":"06","quality_controlled":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.26434/chemrxiv.11447775"}],"publication":"Proceedings of the National Academy of Sciences of the United States of America","abstract":[{"lang":"eng","text":"Electrodepositing insulating lithium peroxide (Li2O2) is the key process during discharge of aprotic Li–O2 batteries and determines rate, capacity, and reversibility. Current understanding states that the partition between surface adsorbed and dissolved lithium superoxide governs whether Li2O2 grows as a conformal surface film or larger particles, leading to low or high capacities, respectively. However, better understanding governing factors for Li2O2 packing density and capacity requires structural sensitive in situ metrologies. Here, we establish in situ small- and wide-angle X-ray scattering (SAXS/WAXS) as a suitable method to record the Li2O2 phase evolution with atomic to submicrometer resolution during cycling a custom-built in situ Li–O2 cell. Combined with sophisticated data analysis, SAXS allows retrieving rich quantitative structural information from complex multiphase systems. Surprisingly, we find that features are absent that would point at a Li2O2 surface film formed via two consecutive electron transfers, even in poorly solvating electrolytes thought to be prototypical for surface growth. All scattering data can be modeled by stacks of thin Li2O2 platelets potentially forming large toroidal particles. Li2O2 solution growth is further justified by rotating ring-disk electrode measurements and electron microscopy. Higher discharge overpotentials lead to smaller Li2O2 particles, but there is no transition to an electronically passivating, conformal Li2O2 coating. Hence, mass transport of reactive species rather than electronic transport through a Li2O2 film limits the discharge capacity. Provided that species mobilities and carbon surface areas are high, this allows for high discharge capacities even in weakly solvating electrolytes. The currently accepted Li–O2 reaction mechanism ought to be reconsidered."}],"intvolume":" 118","title":"In situ small-angle X-ray scattering reveals solution phase discharge of Li–O2 batteries with weakly solvating electrolytes","publication_status":"published","article_type":"original","type":"journal_article","publisher":"National Academy of Sciences","pmid":1,"acknowledged_ssus":[{"_id":"EM-Fac"}],"issue":"14","year":"2021","status":"public","date_published":"2021-04-06T00:00:00Z","date_created":"2021-03-31T07:00:01Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","keyword":["small-angle X-ray scattering","oxygen reduction","disproportionation","Li-air battery"],"external_id":{"pmid":["33785597"],"isi":["000637398300050"]},"date_updated":"2025-06-12T06:56:39Z","department":[{"_id":"StFr"},{"_id":"EM-Fac"}],"oa_version":"Preprint","_id":"9301","article_number":"e2021893118","doi":"10.1073/pnas.2021893118"},{"publisher":"Elsevier","article_type":"original","type":"journal_article","issue":"8","year":"2021","date_published":"2021-08-15T00:00:00Z","status":"public","date_created":"2021-04-04T22:01:20Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","external_id":{"isi":["000655672000005"]},"date_updated":"2025-04-14T07:43:52Z","department":[{"_id":"MaIb"}],"oa_version":"Submitted Version","article_number":"129374","_id":"9304","doi":"10.1016/j.cej.2021.129374","publication_identifier":{"issn":["1385-8947"]},"month":"08","scopus_import":"1","volume":418,"project":[{"grant_number":"754411","_id":"260C2330-B435-11E9-9278-68D0E5697425","name":"ISTplus - Postdoctoral Fellowships","call_identifier":"H2020"}],"language":[{"iso":"eng"}],"author":[{"first_name":"Yu","last_name":"Zhang","full_name":"Zhang, Yu"},{"full_name":"Xing, Congcong","first_name":"Congcong","last_name":"Xing"},{"last_name":"Liu","id":"2A70014E-F248-11E8-B48F-1D18A9856A87","first_name":"Yu","orcid":"0000-0001-7313-6740","full_name":"Liu, Yu"},{"full_name":"Li, Mengyao","last_name":"Li","first_name":"Mengyao"},{"first_name":"Ke","last_name":"Xiao","full_name":"Xiao, Ke"},{"last_name":"Guardia","first_name":"Pablo","full_name":"Guardia, Pablo"},{"orcid":"0000-0002-6962-8598","full_name":"Lee, Seungho","last_name":"Lee","id":"BB243B88-D767-11E9-B658-BC13E6697425","first_name":"Seungho"},{"last_name":"Han","first_name":"Xu","full_name":"Han, Xu"},{"first_name":"Ahmad","last_name":"Moghaddam","full_name":"Moghaddam, Ahmad"},{"first_name":"Joan J","last_name":"Roa","full_name":"Roa, Joan J"},{"first_name":"Jordi","last_name":"Arbiol","full_name":"Arbiol, Jordi"},{"full_name":"Ibáñez, Maria","orcid":"0000-0001-5013-2843","id":"43C61214-F248-11E8-B48F-1D18A9856A87","first_name":"Maria","last_name":"Ibáñez"},{"full_name":"Pan, Kai","first_name":"Kai","last_name":"Pan"},{"first_name":"Mirko","last_name":"Prato","full_name":"Prato, Mirko"},{"full_name":"Xie, Ying","first_name":"Ying","last_name":"Xie"},{"first_name":"Andreu","last_name":"Cabot","full_name":"Cabot, Andreu"}],"article_processing_charge":"No","citation":{"ieee":"Y. Zhang et al., “Influence of copper telluride nanodomains on the transport properties of n-type bismuth telluride,” Chemical Engineering Journal, vol. 418, no. 8. Elsevier, 2021.","mla":"Zhang, Yu, et al. “Influence of Copper Telluride Nanodomains on the Transport Properties of N-Type Bismuth Telluride.” Chemical Engineering Journal, vol. 418, no. 8, 129374, Elsevier, 2021, doi:10.1016/j.cej.2021.129374.","ista":"Zhang Y, Xing C, Liu Y, Li M, Xiao K, Guardia P, Lee S, Han X, Moghaddam A, Roa JJ, Arbiol J, Ibáñez M, Pan K, Prato M, Xie Y, Cabot A. 2021. Influence of copper telluride nanodomains on the transport properties of n-type bismuth telluride. Chemical Engineering Journal. 418(8), 129374.","chicago":"Zhang, Yu, Congcong Xing, Yu Liu, Mengyao Li, Ke Xiao, Pablo Guardia, Seungho Lee, et al. “Influence of Copper Telluride Nanodomains on the Transport Properties of N-Type Bismuth Telluride.” Chemical Engineering Journal. Elsevier, 2021. https://doi.org/10.1016/j.cej.2021.129374.","apa":"Zhang, Y., Xing, C., Liu, Y., Li, M., Xiao, K., Guardia, P., … Cabot, A. (2021). Influence of copper telluride nanodomains on the transport properties of n-type bismuth telluride. Chemical Engineering Journal. Elsevier. https://doi.org/10.1016/j.cej.2021.129374","ama":"Zhang Y, Xing C, Liu Y, et al. Influence of copper telluride nanodomains on the transport properties of n-type bismuth telluride. Chemical Engineering Journal. 2021;418(8). doi:10.1016/j.cej.2021.129374","short":"Y. Zhang, C. Xing, Y. Liu, M. Li, K. Xiao, P. Guardia, S. Lee, X. Han, A. Moghaddam, J.J. Roa, J. Arbiol, M. Ibáñez, K. Pan, M. Prato, Y. Xie, A. Cabot, Chemical Engineering Journal 418 (2021)."},"isi":1,"oa":1,"acknowledgement":"This work was supported by the European Regional Development Funds and by the Generalitat de Catalunya through the project 2017SGR1246. Y.Z, C.X, M.L, K.X and X.H thank the China Scholarship Council for the scholarship support. MI acknowledges financial support from IST Austria. YL acknowledges funding from the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant agreement No. 754411. ICN2\r\nacknowledges funding from Generalitat de Catalunya 2017 SGR 327 and the Spanish MINECO project ENE2017-85087-C3. ICN2 is supported by the Severo Ochoa program from the Spanish MINECO (grant no. SEV-2017-0706) and is funded by the CERCA Program/Generalitat de Catalunya. Part of the present work has been performed in the framework of Universitat Autònoma de Barcelona Materials Science PhD program.","day":"15","quality_controlled":"1","main_file_link":[{"url":"https://ddd.uab.cat/record/271949","open_access":"1"}],"abstract":[{"lang":"eng","text":"The high processing cost, poor mechanical properties and moderate performance of Bi2Te3–based alloys used in thermoelectric devices limit the cost-effectiveness of this energy conversion technology. Towards solving these current challenges, in the present work, we detail a low temperature solution-based approach to produce Bi2Te3-Cu2-xTe nanocomposites with improved thermoelectric performance. Our approach consists in combining proper ratios of colloidal nanoparticles and to consolidate the resulting mixture into nanocomposites using a hot press. The transport properties of the nanocomposites are characterized and compared with those of pure Bi2Te3 nanomaterials obtained following the same procedure. In contrast with most previous works, the presence of Cu2-xTe nanodomains does not result in a significant reduction of the lattice thermal conductivity of the reference Bi2Te3 nanomaterial, which is already very low. However, the introduction of Cu2-xTe yields a nearly threefold increase of the power factor associated to a simultaneous increase of the Seebeck coefficient and electrical conductivity at temperatures above 400 K. Taking into account the band alignment of the two materials, we rationalize this increase by considering that Cu2-xTe nanostructures, with a relatively low electron affinity, are able to inject electrons into Bi2Te3, enhancing in this way its electrical conductivity. The simultaneous increase of the Seebeck coefficient is related to the energy filtering of charge carriers at energy barriers within Bi2Te3 domains associated with the accumulation of electrons in regions nearby a Cu2-xTe/Bi2Te3 heterojunction. Overall, with the incorporation of a proper amount of Cu2-xTe nanoparticles, we demonstrate a 250% improvement of the thermoelectric figure of merit of Bi2Te3."}],"intvolume":" 418","publication":"Chemical Engineering Journal","publication_status":"published","title":"Influence of copper telluride nanodomains on the transport properties of n-type bismuth telluride","ec_funded":1},{"department":[{"_id":"MaIb"}],"date_updated":"2025-04-14T07:43:52Z","external_id":{"isi":["000663442200004"]},"doi":"10.1016/j.nanoen.2021.105991","article_number":"105991","_id":"9305","oa_version":"Submitted Version","year":"2021","issue":"7","publisher":"Elsevier","article_type":"original","type":"journal_article","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2021-04-04T22:01:21Z","date_published":"2021-07-01T00:00:00Z","status":"public","main_file_link":[{"open_access":"1","url":"https://ddd.uab.cat/record/271947"}],"quality_controlled":"1","day":"01","ec_funded":1,"publication_status":"published","title":"Doping-mediated stabilization of copper vacancies to promote thermoelectric properties of Cu2-xS","corr_author":"1","abstract":[{"text":"Copper chalcogenides are outstanding thermoelectric materials for applications in the medium-high temperature range. Among different chalcogenides, while Cu2−xSe is characterized by higher thermoelectric figures of merit, Cu2−xS provides advantages in terms of low cost and element abundance. In the present work, we investigate the effect of different dopants to enhance the Cu2−xS performance and also its thermal stability. Among the tested options, Pb-doped Cu2−xS shows the highest improvement in stability against sulfur volatilization. Additionally, Pb incorporation allows tuning charge carrier concentration, which enables a significant improvement of the power factor. We demonstrate here that the introduction of an optimal additive amount of just 0.3% results in a threefold increase of the power factor in the middle-temperature range (500–800 K) and a record dimensionless thermoelectric figure of merit above 2 at 880 K.","lang":"eng"}],"intvolume":" 85","publication":"Nano Energy","scopus_import":"1","month":"07","volume":85,"publication_identifier":{"issn":["2211-2855"]},"acknowledgement":"This work was supported by the European Regional Development Fund and by the Spanish Ministerio de Economía y Competitividad through the project SEHTOP (ENE2016-77798-C4-3-R). MI acknowledges financial support from IST Austria. YL acknowledges funding from the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant agreement No. 754411. YZ, CX, XW, KX and TZ thank the China Scholarship Council for the scholarship support. ICN2 acknowledges funding from Generalitat de Catalunya 2017 SGR 327 and the Spanish MINECO project ENE2017-85087-C3. ICN2 is supported by the Severo Ochoa program from the Spanish MINECO (grant no. SEV-2017-0706) and is funded by the CERCA program/Generalitat de Catalunya. Part of the present work has been performed in the framework of Universitat Autònoma de Barcelona Materials Science Ph.D. program. M.C.S. has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No. 754510 (PROBIST) and the Severo Ochoa programme. P.G. acknowledges financial support from the Spanish government (MICIU) through the RTI2018-102006-J-I00 project and the Catalan Agency of Competitiveness (ACCIO) through the TecnioSpring+ Marie Sklodowska-Curie action TECSPR16-1-0082. YZ and CX contributed equally to this work.","oa":1,"isi":1,"citation":{"ista":"Zhang Y, Xing C, Liu Y, Spadaro MC, Wang X, Li M, Xiao K, Zhang T, Guardia P, Lim KH, Moghaddam AO, Llorca J, Arbiol J, Ibáñez M, Cabot A. 2021. Doping-mediated stabilization of copper vacancies to promote thermoelectric properties of Cu2-xS. Nano Energy. 85(7), 105991.","chicago":"Zhang, Yu, Congcong Xing, Yu Liu, Maria Chiara Spadaro, Xiang Wang, Mengyao Li, Ke Xiao, et al. “Doping-Mediated Stabilization of Copper Vacancies to Promote Thermoelectric Properties of Cu2-XS.” Nano Energy. Elsevier, 2021. https://doi.org/10.1016/j.nanoen.2021.105991.","apa":"Zhang, Y., Xing, C., Liu, Y., Spadaro, M. C., Wang, X., Li, M., … Cabot, A. (2021). Doping-mediated stabilization of copper vacancies to promote thermoelectric properties of Cu2-xS. Nano Energy. Elsevier. https://doi.org/10.1016/j.nanoen.2021.105991","ama":"Zhang Y, Xing C, Liu Y, et al. Doping-mediated stabilization of copper vacancies to promote thermoelectric properties of Cu2-xS. Nano Energy. 2021;85(7). doi:10.1016/j.nanoen.2021.105991","short":"Y. Zhang, C. Xing, Y. Liu, M.C. Spadaro, X. Wang, M. Li, K. Xiao, T. Zhang, P. Guardia, K.H. Lim, A.O. Moghaddam, J. Llorca, J. Arbiol, M. Ibáñez, A. Cabot, Nano Energy 85 (2021).","mla":"Zhang, Yu, et al. “Doping-Mediated Stabilization of Copper Vacancies to Promote Thermoelectric Properties of Cu2-XS.” Nano Energy, vol. 85, no. 7, 105991, Elsevier, 2021, doi:10.1016/j.nanoen.2021.105991.","ieee":"Y. Zhang et al., “Doping-mediated stabilization of copper vacancies to promote thermoelectric properties of Cu2-xS,” Nano Energy, vol. 85, no. 7. Elsevier, 2021."},"article_processing_charge":"No","project":[{"grant_number":"754411","name":"ISTplus - Postdoctoral Fellowships","call_identifier":"H2020","_id":"260C2330-B435-11E9-9278-68D0E5697425"}],"language":[{"iso":"eng"}],"author":[{"full_name":"Zhang, Yu","last_name":"Zhang","first_name":"Yu"},{"full_name":"Xing, Congcong","first_name":"Congcong","last_name":"Xing"},{"full_name":"Liu, Yu","orcid":"0000-0001-7313-6740","id":"2A70014E-F248-11E8-B48F-1D18A9856A87","first_name":"Yu","last_name":"Liu"},{"full_name":"Spadaro, Maria Chiara","last_name":"Spadaro","first_name":"Maria Chiara"},{"first_name":"Xiang","last_name":"Wang","full_name":"Wang, Xiang"},{"full_name":"Li, Mengyao","last_name":"Li","first_name":"Mengyao"},{"first_name":"Ke","last_name":"Xiao","full_name":"Xiao, Ke"},{"last_name":"Zhang","first_name":"Ting","full_name":"Zhang, Ting"},{"full_name":"Guardia, Pablo","first_name":"Pablo","last_name":"Guardia"},{"last_name":"Lim","first_name":"Khak Ho","full_name":"Lim, Khak Ho"},{"last_name":"Moghaddam","first_name":"Ahmad Ostovari","full_name":"Moghaddam, Ahmad Ostovari"},{"last_name":"Llorca","first_name":"Jordi","full_name":"Llorca, Jordi"},{"first_name":"Jordi","last_name":"Arbiol","full_name":"Arbiol, Jordi"},{"orcid":"0000-0001-5013-2843","full_name":"Ibáñez, Maria","last_name":"Ibáñez","id":"43C61214-F248-11E8-B48F-1D18A9856A87","first_name":"Maria"},{"full_name":"Cabot, Andreu","last_name":"Cabot","first_name":"Andreu"}]},{"isi":1,"article_processing_charge":"No","citation":{"mla":"Dobramysl, Ulrich, et al. “Stochastic Combinations of Actin Regulatory Proteins Are Sufficient to Drive Filopodia Formation.” Journal of Cell Biology, vol. 220, no. 4, e202003052, Rockefeller University Press, 2021, doi:10.1083/jcb.202003052.","ieee":"U. Dobramysl et al., “Stochastic combinations of actin regulatory proteins are sufficient to drive filopodia formation,” Journal of Cell Biology, vol. 220, no. 4. Rockefeller University Press, 2021.","chicago":"Dobramysl, Ulrich, Iris Katharina Jarsch, Yoshiko Inoue, Hanae Shimo, Benjamin Richier, Jonathan R. Gadsby, Julia Mason, et al. “Stochastic Combinations of Actin Regulatory Proteins Are Sufficient to Drive Filopodia Formation.” Journal of Cell Biology. Rockefeller University Press, 2021. https://doi.org/10.1083/jcb.202003052.","ista":"Dobramysl U, Jarsch IK, Inoue Y, Shimo H, Richier B, Gadsby JR, Mason J, Szałapak A, Ioannou PS, Correia GP, Walrant A, Butler R, Hannezo EB, Simons BD, Gallop JL. 2021. Stochastic combinations of actin regulatory proteins are sufficient to drive filopodia formation. Journal of Cell Biology. 220(4), e202003052.","apa":"Dobramysl, U., Jarsch, I. K., Inoue, Y., Shimo, H., Richier, B., Gadsby, J. R., … Gallop, J. L. (2021). Stochastic combinations of actin regulatory proteins are sufficient to drive filopodia formation. Journal of Cell Biology. Rockefeller University Press. https://doi.org/10.1083/jcb.202003052","ama":"Dobramysl U, Jarsch IK, Inoue Y, et al. Stochastic combinations of actin regulatory proteins are sufficient to drive filopodia formation. Journal of Cell Biology. 2021;220(4). doi:10.1083/jcb.202003052","short":"U. Dobramysl, I.K. Jarsch, Y. Inoue, H. Shimo, B. Richier, J.R. Gadsby, J. Mason, A. Szałapak, P.S. Ioannou, G.P. Correia, A. Walrant, R. Butler, E.B. Hannezo, B.D. Simons, J.L. Gallop, Journal of Cell Biology 220 (2021)."},"project":[{"grant_number":"P31639","name":"Active mechano-chemical description of the cell cytoskeleton","call_identifier":"FWF","_id":"268294B6-B435-11E9-9278-68D0E5697425"}],"language":[{"iso":"eng"}],"author":[{"full_name":"Dobramysl, Ulrich","last_name":"Dobramysl","first_name":"Ulrich"},{"first_name":"Iris Katharina","last_name":"Jarsch","full_name":"Jarsch, Iris Katharina"},{"last_name":"Inoue","first_name":"Yoshiko","full_name":"Inoue, Yoshiko"},{"first_name":"Hanae","last_name":"Shimo","full_name":"Shimo, Hanae"},{"full_name":"Richier, Benjamin","first_name":"Benjamin","last_name":"Richier"},{"last_name":"Gadsby","first_name":"Jonathan R.","full_name":"Gadsby, Jonathan R."},{"full_name":"Mason, Julia","first_name":"Julia","last_name":"Mason"},{"full_name":"Szałapak, Alicja","last_name":"Szałapak","first_name":"Alicja"},{"last_name":"Ioannou","first_name":"Pantelis Savvas","full_name":"Ioannou, Pantelis Savvas"},{"full_name":"Correia, Guilherme Pereira","first_name":"Guilherme Pereira","last_name":"Correia"},{"last_name":"Walrant","first_name":"Astrid","full_name":"Walrant, Astrid"},{"first_name":"Richard","last_name":"Butler","full_name":"Butler, Richard"},{"full_name":"Hannezo, Edouard B","orcid":"0000-0001-6005-1561","first_name":"Edouard B","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","last_name":"Hannezo"},{"last_name":"Simons","first_name":"Benjamin D.","full_name":"Simons, Benjamin D."},{"first_name":"Jennifer L.","last_name":"Gallop","full_name":"Gallop, Jennifer L."}],"acknowledgement":"This work was supported by European Research Council grant 281971, Wellcome Trust Research Career Development Fellowship WT095829AIA and Wellcome Trust Senior Research\r\nFellowship 219482/Z/19/Z to J.L. Gallop, a Wellcome Trust Senior Investigator Award 098357 to B.D. Simons, and an Austrian Science Fund grant (P31639) to E. Hannezo. We acknowledge\r\ncore funding by the Wellcome Trust (092096) and Cancer Research UK (C6946/A14492). U. Dobramysl was supported by a Wellcome Trust Junior Interdisciplinary Fellowship grant\r\n(105602/Z/14/Z) and a Herchel Smith Postdoctoral Fellowship. H. Shimo was supported by a Funai Foundation Overseas scholarship.","oa":1,"publication_identifier":{"eissn":["1540-8140"]},"month":"03","scopus_import":"1","volume":220,"publication_status":"published","title":"Stochastic combinations of actin regulatory proteins are sufficient to drive filopodia formation","has_accepted_license":"1","intvolume":" 220","abstract":[{"text":"Assemblies of actin and its regulators underlie the dynamic morphology of all eukaryotic cells. To understand how actin regulatory proteins work together to generate actin-rich structures such as filopodia, we analyzed the localization of diverse actin regulators within filopodia in Drosophila embryos and in a complementary in vitro system of filopodia-like structures (FLSs). We found that the composition of the regulatory protein complex where actin is incorporated (the filopodial tip complex) is remarkably heterogeneous both in vivo and in vitro. Our data reveal that different pairs of proteins correlate with each other and with actin bundle length, suggesting the presence of functional subcomplexes. This is consistent with a theoretical framework where three or more redundant subcomplexes join the tip complex stochastically, with any two being sufficient to drive filopodia formation. We provide an explanation for the observed heterogeneity and suggest that a mechanism based on multiple components allows stereotypical filopodial dynamics to arise from diverse upstream signaling pathways.","lang":"eng"}],"publication":"Journal of Cell Biology","quality_controlled":"1","day":"19","date_published":"2021-03-19T00:00:00Z","status":"public","date_created":"2021-04-04T22:01:21Z","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","publisher":"Rockefeller University Press","type":"journal_article","article_type":"original","year":"2021","issue":"4","pmid":1,"ddc":["576"],"_id":"9306","file":[{"creator":"dernst","file_id":"9310","file_size":9019720,"file_name":"2021_JCB_Dobramysl.pdf","checksum":"4739ffd90f2c7e05ac5b00f057c58aa2","date_updated":"2021-04-06T10:39:08Z","access_level":"open_access","success":1,"content_type":"application/pdf","date_created":"2021-04-06T10:39:08Z","relation":"main_file"}],"article_number":"e202003052","oa_version":"Published Version","file_date_updated":"2021-04-06T10:39:08Z","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"doi":"10.1083/jcb.202003052","date_updated":"2026-04-02T13:59:43Z","external_id":{"isi":["000663160600002"],"pmid":["33740033"]},"department":[{"_id":"EdHa"}]},{"ddc":["510"],"year":"2021","article_type":"original","type":"journal_article","publisher":"Springer Nature","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","date_created":"2021-04-04T22:01:21Z","status":"public","date_published":"2021-03-21T00:00:00Z","department":[{"_id":"JuFi"}],"external_id":{"isi":["000631001700001"]},"date_updated":"2025-03-31T16:00:58Z","doi":"10.1007/s40072-021-00188-9","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"file_date_updated":"2021-04-06T09:31:28Z","oa_version":"Published Version","_id":"9307","file":[{"relation":"main_file","content_type":"application/pdf","success":1,"date_created":"2021-04-06T09:31:28Z","date_updated":"2021-04-06T09:31:28Z","access_level":"open_access","checksum":"6529b609c9209861720ffa4685111bc6","file_id":"9309","file_size":727005,"file_name":"2021_StochPartDiffEquation_Hensel.pdf","creator":"dernst"}],"volume":9,"scopus_import":"1","month":"03","publication_identifier":{"eissn":["2194-041X"],"issn":["2194-0401"]},"oa":1,"acknowledgement":"This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 665385 . I am very grateful to M. Gerencsér and J. Maas for proposing this problem as well as helpful discussions. Special thanks go to F. Cornalba for suggesting the additional κ-truncation in Proposition 5. I am also indebted to an anonymous referee for pointing out a gap in a previous version of the proof of Lemma 9 (concerning the treatment of the noise term). The issue is resolved in this version.","author":[{"full_name":"Hensel, Sebastian","orcid":"0000-0001-7252-8072","first_name":"Sebastian","id":"4D23B7DA-F248-11E8-B48F-1D18A9856A87","last_name":"Hensel"}],"project":[{"grant_number":"665385","name":"International IST Doctoral Program","call_identifier":"H2020","_id":"2564DBCA-B435-11E9-9278-68D0E5697425"}],"language":[{"iso":"eng"}],"page":"892–939","article_processing_charge":"Yes (via OA deal)","isi":1,"citation":{"mla":"Hensel, Sebastian. “Finite Time Extinction for the 1D Stochastic Porous Medium Equation with Transport Noise.” Stochastics and Partial Differential Equations: Analysis and Computations, vol. 9, Springer Nature, 2021, pp. 892–939, doi:10.1007/s40072-021-00188-9.","ieee":"S. Hensel, “Finite time extinction for the 1D stochastic porous medium equation with transport noise,” Stochastics and Partial Differential Equations: Analysis and Computations, vol. 9. Springer Nature, pp. 892–939, 2021.","short":"S. Hensel, Stochastics and Partial Differential Equations: Analysis and Computations 9 (2021) 892–939.","ista":"Hensel S. 2021. Finite time extinction for the 1D stochastic porous medium equation with transport noise. Stochastics and Partial Differential Equations: Analysis and Computations. 9, 892–939.","chicago":"Hensel, Sebastian. “Finite Time Extinction for the 1D Stochastic Porous Medium Equation with Transport Noise.” Stochastics and Partial Differential Equations: Analysis and Computations. Springer Nature, 2021. https://doi.org/10.1007/s40072-021-00188-9.","apa":"Hensel, S. (2021). Finite time extinction for the 1D stochastic porous medium equation with transport noise. Stochastics and Partial Differential Equations: Analysis and Computations. Springer Nature. https://doi.org/10.1007/s40072-021-00188-9","ama":"Hensel S. Finite time extinction for the 1D stochastic porous medium equation with transport noise. Stochastics and Partial Differential Equations: Analysis and Computations. 2021;9:892–939. doi:10.1007/s40072-021-00188-9"},"day":"21","quality_controlled":"1","ec_funded":1,"publication":"Stochastics and Partial Differential Equations: Analysis and Computations","intvolume":" 9","abstract":[{"lang":"eng","text":"We establish finite time extinction with probability one for weak solutions of the Cauchy–Dirichlet problem for the 1D stochastic porous medium equation with Stratonovich transport noise and compactly supported smooth initial datum. Heuristically, this is expected to hold because Brownian motion has average spread rate O(t12) whereas the support of solutions to the deterministic PME grows only with rate O(t1m+1). The rigorous proof relies on a contraction principle up to time-dependent shift for Wong–Zakai type approximations, the transformation to a deterministic PME with two copies of a Brownian path as the lateral boundary, and techniques from the theory of viscosity solutions."}],"has_accepted_license":"1","title":"Finite time extinction for the 1D stochastic porous medium equation with transport noise","publication_status":"published"},{"volume":76,"month":"03","scopus_import":"1","publication_identifier":{"issn":["1422-6383"],"eissn":["1420-9012"]},"acknowledgement":"The research of this author is supported by the Postdoctoral Fellowship from Institute of Science and Technology (IST), Austria.","article_processing_charge":"No","isi":1,"citation":{"ieee":"O. S. Iyiola and Y. Shehu, “New convergence results for inertial Krasnoselskii–Mann iterations in Hilbert spaces with applications,” Results in Mathematics, vol. 76, no. 2. Springer Nature, 2021.","mla":"Iyiola, Olaniyi S., and Yekini Shehu. “New Convergence Results for Inertial Krasnoselskii–Mann Iterations in Hilbert Spaces with Applications.” Results in Mathematics, vol. 76, no. 2, 75, Springer Nature, 2021, doi:10.1007/s00025-021-01381-x.","apa":"Iyiola, O. S., & Shehu, Y. (2021). New convergence results for inertial Krasnoselskii–Mann iterations in Hilbert spaces with applications. Results in Mathematics. Springer Nature. https://doi.org/10.1007/s00025-021-01381-x","ama":"Iyiola OS, Shehu Y. New convergence results for inertial Krasnoselskii–Mann iterations in Hilbert spaces with applications. Results in Mathematics. 2021;76(2). doi:10.1007/s00025-021-01381-x","chicago":"Iyiola, Olaniyi S., and Yekini Shehu. “New Convergence Results for Inertial Krasnoselskii–Mann Iterations in Hilbert Spaces with Applications.” Results in Mathematics. Springer Nature, 2021. https://doi.org/10.1007/s00025-021-01381-x.","ista":"Iyiola OS, Shehu Y. 2021. New convergence results for inertial Krasnoselskii–Mann iterations in Hilbert spaces with applications. Results in Mathematics. 76(2), 75.","short":"O.S. Iyiola, Y. Shehu, Results in Mathematics 76 (2021)."},"author":[{"last_name":"Iyiola","first_name":"Olaniyi S.","full_name":"Iyiola, Olaniyi S."},{"id":"3FC7CB58-F248-11E8-B48F-1D18A9856A87","first_name":"Yekini","last_name":"Shehu","full_name":"Shehu, Yekini","orcid":"0000-0001-9224-7139"}],"language":[{"iso":"eng"}],"quality_controlled":"1","day":"25","publication_status":"published","title":"New convergence results for inertial Krasnoselskii–Mann iterations in Hilbert spaces with applications","corr_author":"1","publication":"Results in Mathematics","intvolume":" 76","abstract":[{"lang":"eng","text":"We consider inertial iteration methods for Fermat–Weber location problem and primal–dual three-operator splitting in real Hilbert spaces. To do these, we first obtain weak convergence analysis and nonasymptotic O(1/n) convergence rate of the inertial Krasnoselskii–Mann iteration for fixed point of nonexpansive operators in infinite dimensional real Hilbert spaces under some seemingly easy to implement conditions on the iterative parameters. One of our contributions is that the convergence analysis and rate of convergence results are obtained using conditions which appear not complicated and restrictive as assumed in other previous related results in the literature. We then show that Fermat–Weber location problem and primal–dual three-operator splitting are special cases of fixed point problem of nonexpansive mapping and consequently obtain the convergence analysis of inertial iteration methods for Fermat–Weber location problem and primal–dual three-operator splitting in real Hilbert spaces. Some numerical implementations are drawn from primal–dual three-operator splitting to support the theoretical analysis."}],"year":"2021","issue":"2","type":"journal_article","article_type":"original","publisher":"Springer Nature","date_created":"2021-04-11T22:01:14Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","date_published":"2021-03-25T00:00:00Z","department":[{"_id":"VlKo"}],"date_updated":"2024-10-09T21:00:33Z","external_id":{"isi":["000632917700001"]},"doi":"10.1007/s00025-021-01381-x","article_number":"75","_id":"9315","oa_version":"None"},{"author":[{"full_name":"Petridou, Nicoletta","orcid":"0000-0002-8451-1195","first_name":"Nicoletta","id":"2A003F6C-F248-11E8-B48F-1D18A9856A87","last_name":"Petridou"},{"full_name":"Corominas-Murtra, Bernat","orcid":"0000-0001-9806-5643","first_name":"Bernat","id":"43BE2298-F248-11E8-B48F-1D18A9856A87","last_name":"Corominas-Murtra"},{"full_name":"Heisenberg, Carl-Philipp J","orcid":"0000-0002-0912-4566","id":"39427864-F248-11E8-B48F-1D18A9856A87","first_name":"Carl-Philipp J","last_name":"Heisenberg"},{"first_name":"Edouard B","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","last_name":"Hannezo","full_name":"Hannezo, Edouard B","orcid":"0000-0001-6005-1561"}],"project":[{"grant_number":"742573","_id":"260F1432-B435-11E9-9278-68D0E5697425","name":"Interaction and feedback between cell mechanics and fate specification in vertebrate gastrulation","call_identifier":"H2020"},{"grant_number":"851288","name":"Design Principles of Branching Morphogenesis","call_identifier":"H2020","_id":"05943252-7A3F-11EA-A408-12923DDC885E"},{"_id":"2693FD8C-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","name":"Tissue material properties in embryonic development","grant_number":"V00736"}],"language":[{"iso":"eng"}],"page":"1914-1928.e19","isi":1,"article_processing_charge":"No","citation":{"apa":"Petridou, N., Corominas-Murtra, B., Heisenberg, C.-P. J., & Hannezo, E. B. (2021). Rigidity percolation uncovers a structural basis for embryonic tissue phase transitions. Cell. Elsevier. https://doi.org/10.1016/j.cell.2021.02.017","ama":"Petridou N, Corominas-Murtra B, Heisenberg C-PJ, Hannezo EB. Rigidity percolation uncovers a structural basis for embryonic tissue phase transitions. Cell. 2021;184(7):1914-1928.e19. doi:10.1016/j.cell.2021.02.017","chicago":"Petridou, Nicoletta, Bernat Corominas-Murtra, Carl-Philipp J Heisenberg, and Edouard B Hannezo. “Rigidity Percolation Uncovers a Structural Basis for Embryonic Tissue Phase Transitions.” Cell. Elsevier, 2021. https://doi.org/10.1016/j.cell.2021.02.017.","ista":"Petridou N, Corominas-Murtra B, Heisenberg C-PJ, Hannezo EB. 2021. Rigidity percolation uncovers a structural basis for embryonic tissue phase transitions. Cell. 184(7), 1914–1928.e19.","short":"N. Petridou, B. Corominas-Murtra, C.-P.J. Heisenberg, E.B. Hannezo, Cell 184 (2021) 1914–1928.e19.","ieee":"N. Petridou, B. Corominas-Murtra, C.-P. J. Heisenberg, and E. B. Hannezo, “Rigidity percolation uncovers a structural basis for embryonic tissue phase transitions,” Cell, vol. 184, no. 7. Elsevier, p. 1914–1928.e19, 2021.","mla":"Petridou, Nicoletta, et al. “Rigidity Percolation Uncovers a Structural Basis for Embryonic Tissue Phase Transitions.” Cell, vol. 184, no. 7, Elsevier, 2021, p. 1914–1928.e19, doi:10.1016/j.cell.2021.02.017."},"oa":1,"acknowledgement":"We thank Carl Goodrich and the members of the Heisenberg and Hannezo groups, in particular Reka Korei, for help, technical advice, and discussions; and the Bioimaging and zebrafish facilities of the IST Austria for continuous support. This work was supported by the Elise Richter Program of Austrian Science Fund (FWF) to N.I.P. ( V 736-B26 ) and the European Union (European Research Council Advanced Grant 742573 to C.-P.H. and European Research Council Starting Grant 851288 to E.H.).","publication_identifier":{"issn":["0092-8674"],"eissn":["1097-4172"]},"volume":184,"scopus_import":"1","month":"04","publication":"Cell","abstract":[{"lang":"eng","text":"Embryo morphogenesis is impacted by dynamic changes in tissue material properties, which have been proposed to occur via processes akin to phase transitions (PTs). Here, we show that rigidity percolation provides a simple and robust theoretical framework to predict material/structural PTs of embryonic tissues from local cell connectivity. By using percolation theory, combined with directly monitoring dynamic changes in tissue rheology and cell contact mechanics, we demonstrate that the zebrafish blastoderm undergoes a genuine rigidity PT, brought about by a small reduction in adhesion-dependent cell connectivity below a critical value. We quantitatively predict and experimentally verify hallmarks of PTs, including power-law exponents and associated discontinuities of macroscopic observables. Finally, we show that this uniform PT depends on blastoderm cells undergoing meta-synchronous divisions causing random and, consequently, uniform changes in cell connectivity. Collectively, our theoretical and experimental findings reveal the structural basis of material PTs in an organismal context."}],"intvolume":" 184","has_accepted_license":"1","title":"Rigidity percolation uncovers a structural basis for embryonic tissue phase transitions","corr_author":"1","publication_status":"published","ec_funded":1,"day":"01","quality_controlled":"1","status":"public","date_published":"2021-04-01T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2021-04-11T22:01:14Z","type":"journal_article","article_type":"original","publisher":"Elsevier","ddc":["570"],"pmid":1,"acknowledged_ssus":[{"_id":"Bio"},{"_id":"PreCl"}],"issue":"7","year":"2021","file_date_updated":"2021-06-08T10:04:10Z","oa_version":"Published Version","file":[{"date_created":"2021-06-08T10:04:10Z","success":1,"content_type":"application/pdf","relation":"main_file","file_size":11405875,"file_name":"2021_Cell_Petridou.pdf","file_id":"9534","creator":"cziletti","access_level":"open_access","date_updated":"2021-06-08T10:04:10Z","checksum":"1e5295fbd9c2a459173ec45a0e8a7c2e"}],"_id":"9316","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"doi":"10.1016/j.cell.2021.02.017","external_id":{"isi":["000636734000022"],"pmid":["33730596"]},"related_material":{"link":[{"url":"https://ist.ac.at/en/news/embryonic-tissue-undergoes-phase-transition/","description":"News on IST Homepage","relation":"press_release"}]},"date_updated":"2025-07-10T12:01:42Z","department":[{"_id":"CaHe"},{"_id":"EdHa"}]}]