[{"external_id":{"isi":["000744439800005"]},"page":"55-65","citation":{"ieee":"D.-A. Alistarh, M. Töpfer, and P. Uznański, “Comparison dynamics in population protocols,” in <i>Proceedings of the 2021 ACM Symposium on Principles of Distributed Computing</i>, Virtual, Italy, 2021, pp. 55–65.","short":"D.-A. Alistarh, M. Töpfer, P. Uznański, in:, Proceedings of the 2021 ACM Symposium on Principles of Distributed Computing, Association for Computing Machinery, 2021, pp. 55–65.","ista":"Alistarh D-A, Töpfer M, Uznański P. 2021. Comparison dynamics in population protocols. Proceedings of the 2021 ACM Symposium on Principles of Distributed Computing. PODC: Symposium on Principles of Distributed Computing, 55–65.","ama":"Alistarh D-A, Töpfer M, Uznański P. Comparison dynamics in population protocols. In: <i>Proceedings of the 2021 ACM Symposium on Principles of Distributed Computing</i>. Association for Computing Machinery; 2021:55-65. doi:<a href=\"https://doi.org/10.1145/3465084.3467915\">10.1145/3465084.3467915</a>","apa":"Alistarh, D.-A., Töpfer, M., &#38; Uznański, P. (2021). Comparison dynamics in population protocols. In <i>Proceedings of the 2021 ACM Symposium on Principles of Distributed Computing</i> (pp. 55–65). Virtual, Italy: Association for Computing Machinery. <a href=\"https://doi.org/10.1145/3465084.3467915\">https://doi.org/10.1145/3465084.3467915</a>","mla":"Alistarh, Dan-Adrian, et al. “Comparison Dynamics in Population Protocols.” <i>Proceedings of the 2021 ACM Symposium on Principles of Distributed Computing</i>, Association for Computing Machinery, 2021, pp. 55–65, doi:<a href=\"https://doi.org/10.1145/3465084.3467915\">10.1145/3465084.3467915</a>.","chicago":"Alistarh, Dan-Adrian, Martin Töpfer, and Przemysław Uznański. “Comparison Dynamics in Population Protocols.” In <i>Proceedings of the 2021 ACM Symposium on Principles of Distributed Computing</i>, 55–65. Association for Computing Machinery, 2021. <a href=\"https://doi.org/10.1145/3465084.3467915\">https://doi.org/10.1145/3465084.3467915</a>."},"acknowledgement":"We would like to thank Rati Gelashvili for very useful discussions, and the PODC anonymous reviewers for their careful reading of our paper, and for their useful remarks. This work is partially supported by the Polish National Science Center (NCN) grant UMO2017/25/B/ST6/02010.","publication_status":"published","department":[{"_id":"DaAl"}],"date_updated":"2023-08-11T10:56:04Z","quality_controlled":"1","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","oa_version":"None","date_created":"2021-08-22T22:01:20Z","language":[{"iso":"eng"}],"date_published":"2021-07-21T00:00:00Z","type":"conference","isi":1,"author":[{"id":"4A899BFC-F248-11E8-B48F-1D18A9856A87","full_name":"Alistarh, Dan-Adrian","first_name":"Dan-Adrian","orcid":"0000-0003-3650-940X","last_name":"Alistarh"},{"first_name":"Martin","full_name":"Töpfer, Martin","id":"4B865388-F248-11E8-B48F-1D18A9856A87","last_name":"Töpfer"},{"last_name":"Uznański","full_name":"Uznański, Przemysław","first_name":"Przemysław"}],"abstract":[{"text":"There has recently been a surge of interest in the computational and complexity properties of the population model, which assumes n anonymous, computationally-bounded nodes, interacting at random, with the goal of jointly computing global predicates. Significant work has gone towards investigating majority or consensus dynamics in this model: that is, assuming that every node is initially in one of two states X or Y, determine which state had higher initial count.\r\n\r\nIn this paper, we consider a natural generalization of majority/consensus, which we call comparison : in its simplest formulation, we are given two baseline states, X and Y, present in any initial configuration in fixed, but possibly small counts. One of these states has higher count than the other: we will assume |X_0| > C |Y_0| for some constant C > 1. The challenge is to design a protocol by which nodes can quickly and reliably decide on which of the baseline states X_0 and Y_0 has higher initial count. We begin by analyzing a simple and general dynamics solving the above comparison problem, which uses O( log n ) states per node, and converges in O(log n) (parallel) time, with high probability, to a state where the whole population votes on opinions X or Y at rates proportional to the initial concentrations of |X_0| vs. |Y_0|. We then describe how this procedure can be bootstrapped to solve comparison, i.e. have every node in the population reach the \"correct'' decision, with probability 1 - o(1), at the cost of O (log log n) additional states. Further, we prove that this dynamics is self-stabilizing, in the sense that it converges to the correct decision from arbitrary initial states, and leak-robust, in the sense that it can withstand spurious faulty reactions, which are known to occur in practical implementations of population protocols. Our analysis is based on a new martingale concentration result relating the discrete-time evolution of a population protocol to its expected (steady-state) analysis, which should be a useful tool when analyzing opinion dynamics and epidemic dissemination in the population model.","lang":"eng"}],"day":"21","publication_identifier":{"isbn":["9781450385480"]},"publisher":"Association for Computing Machinery","doi":"10.1145/3465084.3467915","fulldoi":"https://doi.org/10.1145/3465084.3467915","title":"Comparison dynamics in population protocols","scopus_import":"1","article_processing_charge":"No","year":"2021","month":"07","status":"public","_id":"9951","conference":{"start_date":"2021-07-26","end_date":"2021-07-30","name":"PODC: Symposium on Principles of Distributed Computing","location":"Virtual, Italy"},"publication":"Proceedings of the 2021 ACM Symposium on Principles of Distributed Computing"},{"issue":"14","citation":{"mla":"Chaigne, Agathe, et al. “Three-Dimensional Geometry Controls Division Symmetry in Stem Cell Colonies.” <i>Journal of Cell Science</i>, vol. 134, no. 14, jcs255018, The Company of Biologists, 2021, doi:<a href=\"https://doi.org/10.1242/jcs.255018\">10.1242/jcs.255018</a>.","apa":"Chaigne, A., Smith, M. B., Cavestany, R. L., Hannezo, E. B., Chalut, K. J., &#38; Paluch, E. K. (2021). Three-dimensional geometry controls division symmetry in stem cell colonies. <i>Journal of Cell Science</i>. The Company of Biologists. <a href=\"https://doi.org/10.1242/jcs.255018\">https://doi.org/10.1242/jcs.255018</a>","ista":"Chaigne A, Smith MB, Cavestany RL, Hannezo EB, Chalut KJ, Paluch EK. 2021. Three-dimensional geometry controls division symmetry in stem cell colonies. Journal of Cell Science. 134(14), jcs255018.","ama":"Chaigne A, Smith MB, Cavestany RL, Hannezo EB, Chalut KJ, Paluch EK. Three-dimensional geometry controls division symmetry in stem cell colonies. <i>Journal of Cell Science</i>. 2021;134(14). doi:<a href=\"https://doi.org/10.1242/jcs.255018\">10.1242/jcs.255018</a>","short":"A. Chaigne, M.B. Smith, R.L. Cavestany, E.B. Hannezo, K.J. Chalut, E.K. Paluch, Journal of Cell Science 134 (2021).","ieee":"A. Chaigne, M. B. Smith, R. L. Cavestany, E. B. Hannezo, K. J. Chalut, and E. K. Paluch, “Three-dimensional geometry controls division symmetry in stem cell colonies,” <i>Journal of Cell Science</i>, vol. 134, no. 14. The Company of Biologists, 2021.","chicago":"Chaigne, Agathe, Matthew B. Smith, R. L. Cavestany, Edouard B Hannezo, Kevin J. Chalut, and Ewa K. Paluch. “Three-Dimensional Geometry Controls Division Symmetry in Stem Cell Colonies.” <i>Journal of Cell Science</i>. The Company of Biologists, 2021. <a href=\"https://doi.org/10.1242/jcs.255018\">https://doi.org/10.1242/jcs.255018</a>."},"external_id":{"isi":["000681395800008"]},"volume":134,"acknowledgement":"We would like to thank the entire Paluch and Baum laboratories at the MRC-LMCB and the Chalut lab at the Cambridge SCI for discussions and feedback throughout the project, and the MRC-LMCB microscopy platform, in particular Andrew Vaughan, for technical support.","department":[{"_id":"EdHa"}],"publication_status":"published","date_updated":"2025-07-10T12:02:07Z","article_type":"original","tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"file":[{"content_type":"application/pdf","file_name":"2021_JournalOfCellScience_Chaigne.pdf","success":1,"date_updated":"2021-08-23T07:32:20Z","file_id":"9954","checksum":"f086f9d7cb63b2474c01921cb060c513","relation":"main_file","access_level":"open_access","date_created":"2021-08-23T07:32:20Z","file_size":8651724,"creator":"asandaue"}],"quality_controlled":"1","intvolume":"       134","language":[{"iso":"eng"}],"oa_version":"Published Version","date_created":"2021-08-22T22:01:20Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2021-07-01T00:00:00Z","type":"journal_article","has_accepted_license":"1","isi":1,"article_number":"jcs255018","author":[{"full_name":"Chaigne, Agathe","first_name":"Agathe","last_name":"Chaigne"},{"last_name":"Smith","first_name":"Matthew B.","full_name":"Smith, Matthew B."},{"full_name":"Cavestany, R. L.","first_name":"R. L.","last_name":"Cavestany"},{"last_name":"Hannezo","full_name":"Hannezo, Edouard B","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","first_name":"Edouard B","orcid":"0000-0001-6005-1561"},{"last_name":"Chalut","full_name":"Chalut, Kevin J.","first_name":"Kevin J."},{"first_name":"Ewa K.","full_name":"Paluch, Ewa K.","last_name":"Paluch"}],"abstract":[{"text":"Proper control of division orientation and symmetry, largely determined by spindle positioning, is essential to development and homeostasis. Spindle positioning has been extensively studied in cells dividing in two-dimensional (2D) environments and in epithelial tissues, where proteins such as NuMA (also known as NUMA1) orient division along the interphase long axis of the cell. However, little is known about how cells control spindle positioning in three-dimensional (3D) environments, such as early mammalian embryos and a variety of adult tissues. Here, we use mouse embryonic stem cells (ESCs), which grow in 3D colonies, as a model to investigate division in 3D. We observe that, at the periphery of 3D colonies, ESCs display high spindle mobility and divide asymmetrically. Our data suggest that enhanced spindle movements are due to unequal distribution of the cell–cell junction protein E-cadherin between future daughter cells. Interestingly, when cells progress towards differentiation, division becomes more symmetric, with more elongated shapes in metaphase and enhanced cortical NuMA recruitment in anaphase. Altogether, this study suggests that in 3D contexts, the geometry of the cell and its contacts with neighbors control division orientation and symmetry.","lang":"eng"}],"day":"01","publication_identifier":{"eissn":["1477-9137"],"issn":["0021-9533"]},"file_date_updated":"2021-08-23T07:32:20Z","doi":"10.1242/jcs.255018","publisher":"The Company of Biologists","ddc":["570"],"fulldoi":"https://doi.org/10.1242/jcs.255018","scopus_import":"1","title":"Three-dimensional geometry controls division symmetry in stem cell colonies","article_processing_charge":"Yes (in subscription journal)","oa":1,"status":"public","_id":"9952","month":"07","year":"2021","publication":"Journal of Cell Science"},{"quality_controlled":"1","intvolume":"        97","language":[{"iso":"eng"}],"oa_version":"Submitted Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2021-08-22T22:01:21Z","date_published":"2021-10-01T00:00:00Z","type":"journal_article","department":[{"_id":"GaNo"}],"publication_status":"published","date_updated":"2023-10-03T09:49:18Z","article_type":"original","acknowledgement":"We acknowledge that Université Laval stands on the traditional and unceded land of the Huron-Wendat peoples; and that the University of Victoria exists on the territory of the Lekwungen peoples and that the Songhees, Esquimalt and WSÁNEÆ peoples have relationships to this land. We thank Emmanuel Planel for the access to the epifluorescence microscope and Julie-Christine Lévesque at the Bioimaging Platform of CRCHU de Québec-Université Laval for technical assistance. We also thank the Centre for Advanced Materials and Related Technology for the access to the confocal microscope with Airyscan. K.P. was supported by a doctoral scholarship from Fonds de Recherche du Québec – Santé (FRQS), an excellence award from Fondation du CHU de Québec, as well as from Centre Thématique de Recherche en Neurosciences and from Fondation Famille-Choquette. K.B. was supported by excellence scholarships from Université Laval and Fondation du CHU de Québec. S.G. is supported by FIRC-AIRC fellowship for Italy 22329/2018 and by Pilot ARISLA NKINALS 2019. C.W.H. and J.C.S. were supported by postdoctoral fellowships from FRQS. This study was funded by a Natural Sciences and Engineering Research Council of Canada (NSERC) Discovery grant (RGPIN-2014-05308) awarded to M.E.T., by ERANET neuron 2017 MicroSynDep to M.E.T. and I.B., and by the Italian Ministry of Health, grant RF-2018-12367249 to I.B, by PRIN 2017, AIRC 2019 and Ministero della Salute RF2018 to C.L. M.E.T. is a Tier II Canada Research Chair in Neurobiology of Aging and Cognition.","volume":97,"main_file_link":[{"url":"https://www.zora.uzh.ch/id/eprint/208855/1/ZORA208855.pdf","open_access":"1"}],"citation":{"ieee":"K. Picard <i>et al.</i>, “Microglial-glucocorticoid receptor depletion alters the response of hippocampal microglia and neurons in a chronic unpredictable mild stress paradigm in female mice,” <i>Brain, Behavior, and Immunity</i>, vol. 97. Elsevier, pp. 423–439, 2021.","short":"K. Picard, K. Bisht, S. Poggini, S. Garofalo, M.T. Golia, B. Basilico, F. Abdallah, N. Ciano Albanese, I. Amrein, N. Vernoux, K. Sharma, C.W. Hui, J. C. Savage, C. Limatola, D. Ragozzino, L. Maggi, I. Branchi, M.È. Tremblay, Brain, Behavior, and Immunity 97 (2021) 423–439.","ista":"Picard K, Bisht K, Poggini S, Garofalo S, Golia MT, Basilico B, Abdallah F, Ciano Albanese N, Amrein I, Vernoux N, Sharma K, Hui CW, C. Savage J, Limatola C, Ragozzino D, Maggi L, Branchi I, Tremblay MÈ. 2021. Microglial-glucocorticoid receptor depletion alters the response of hippocampal microglia and neurons in a chronic unpredictable mild stress paradigm in female mice. Brain, Behavior, and Immunity. 97, 423–439.","ama":"Picard K, Bisht K, Poggini S, et al. Microglial-glucocorticoid receptor depletion alters the response of hippocampal microglia and neurons in a chronic unpredictable mild stress paradigm in female mice. <i>Brain, Behavior, and Immunity</i>. 2021;97:423-439. doi:<a href=\"https://doi.org/10.1016/j.bbi.2021.07.022\">10.1016/j.bbi.2021.07.022</a>","apa":"Picard, K., Bisht, K., Poggini, S., Garofalo, S., Golia, M. T., Basilico, B., … Tremblay, M. È. (2021). Microglial-glucocorticoid receptor depletion alters the response of hippocampal microglia and neurons in a chronic unpredictable mild stress paradigm in female mice. <i>Brain, Behavior, and Immunity</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.bbi.2021.07.022\">https://doi.org/10.1016/j.bbi.2021.07.022</a>","mla":"Picard, Katherine, et al. “Microglial-Glucocorticoid Receptor Depletion Alters the Response of Hippocampal Microglia and Neurons in a Chronic Unpredictable Mild Stress Paradigm in Female Mice.” <i>Brain, Behavior, and Immunity</i>, vol. 97, Elsevier, 2021, pp. 423–39, doi:<a href=\"https://doi.org/10.1016/j.bbi.2021.07.022\">10.1016/j.bbi.2021.07.022</a>.","chicago":"Picard, Katherine, Kanchan Bisht, Silvia Poggini, Stefano Garofalo, Maria Teresa Golia, Bernadette Basilico, Fatima Abdallah, et al. “Microglial-Glucocorticoid Receptor Depletion Alters the Response of Hippocampal Microglia and Neurons in a Chronic Unpredictable Mild Stress Paradigm in Female Mice.” <i>Brain, Behavior, and Immunity</i>. Elsevier, 2021. <a href=\"https://doi.org/10.1016/j.bbi.2021.07.022\">https://doi.org/10.1016/j.bbi.2021.07.022</a>."},"page":"423-439","external_id":{"pmid":["34343616"],"isi":["000702878400007"]},"scopus_import":"1","title":"Microglial-glucocorticoid receptor depletion alters the response of hippocampal microglia and neurons in a chronic unpredictable mild stress paradigm in female mice","article_processing_charge":"No","oa":1,"_id":"9953","status":"public","month":"10","year":"2021","publication":"Brain, Behavior, and Immunity","day":"01","publication_identifier":{"issn":["0889-1591"]},"doi":"10.1016/j.bbi.2021.07.022","publisher":"Elsevier","fulldoi":"https://doi.org/10.1016/j.bbi.2021.07.022","author":[{"last_name":"Picard","first_name":"Katherine","full_name":"Picard, Katherine"},{"last_name":"Bisht","full_name":"Bisht, Kanchan","first_name":"Kanchan"},{"last_name":"Poggini","first_name":"Silvia","full_name":"Poggini, Silvia"},{"first_name":"Stefano","full_name":"Garofalo, Stefano","last_name":"Garofalo"},{"last_name":"Golia","full_name":"Golia, Maria Teresa","first_name":"Maria Teresa"},{"full_name":"Basilico, Bernadette","id":"36035796-5ACA-11E9-A75E-7AF2E5697425","orcid":"0000-0003-1843-3173","first_name":"Bernadette","last_name":"Basilico"},{"first_name":"Fatima","full_name":"Abdallah, Fatima","last_name":"Abdallah"},{"last_name":"Ciano Albanese","full_name":"Ciano Albanese, Naomi","first_name":"Naomi"},{"full_name":"Amrein, Irmgard","first_name":"Irmgard","last_name":"Amrein"},{"full_name":"Vernoux, Nathalie","first_name":"Nathalie","last_name":"Vernoux"},{"first_name":"Kaushik","full_name":"Sharma, Kaushik","last_name":"Sharma"},{"last_name":"Hui","full_name":"Hui, Chin Wai","first_name":"Chin Wai"},{"last_name":"C. Savage","first_name":"Julie","full_name":"C. Savage, Julie"},{"last_name":"Limatola","full_name":"Limatola, Cristina","first_name":"Cristina"},{"full_name":"Ragozzino, Davide","first_name":"Davide","last_name":"Ragozzino"},{"last_name":"Maggi","full_name":"Maggi, Laura","first_name":"Laura"},{"full_name":"Branchi, Igor","first_name":"Igor","last_name":"Branchi"},{"last_name":"Tremblay","full_name":"Tremblay, Marie Ève","first_name":"Marie Ève"}],"pmid":1,"abstract":[{"text":"Chronic psychological stress is one of the most important triggers and environmental risk factors for neuropsychiatric disorders. Chronic stress can influence all organs via the secretion of stress hormones, including glucocorticoids by the adrenal glands, which coordinate the stress response across the body. In the brain, glucocorticoid receptors (GR) are expressed by various cell types including microglia, which are its resident immune cells regulating stress-induced inflammatory processes. To study the roles of microglial GR under normal homeostatic conditions and following chronic stress, we generated a mouse model in which the GR gene is depleted in microglia specifically at adulthood to prevent developmental confounds. We first confirmed that microglia were depleted in GR in our model in males and females among the cingulate cortex and the hippocampus, both stress-sensitive brain regions. Then, cohorts of microglial-GR depleted and wild-type (WT) adult female mice were housed for 3 weeks in a standard or stressful condition, using a chronic unpredictable mild stress (CUMS) paradigm. CUMS induced stress-related behavior in both microglial-GR depleted and WT animals as demonstrated by a decrease of both saccharine preference and progressive ratio breakpoint. Nevertheless, the hippocampal microglial and neural mechanisms underlying the adaptation to stress occurred differently between the two genotypes. Upon CUMS exposure, microglial morphology was altered in the WT controls, without any apparent effect in microglial-GR depleted mice. Furthermore, in the standard environment condition, GR depleted-microglia showed increased expression of pro-inflammatory genes, and genes involved in microglial homeostatic functions (such as Trem2, Cx3cr1 and Mertk). On the contrary, in CUMS condition, GR depleted-microglia showed reduced expression levels of pro-inflammatory genes and increased neuroprotective as well as anti-inflammatory genes compared to WT-microglia. Moreover, in microglial-GR depleted mice, but not in WT mice, CUMS led to a significant reduction of CA1 long-term potentiation and paired-pulse ratio. Lastly, differences in adult hippocampal neurogenesis were observed between the genotypes during normal homeostatic conditions, with microglial-GR deficiency increasing the formation of newborn neurons in the dentate gyrus subgranular zone independently from stress exposure. Together, these findings indicate that, although the deletion of microglial GR did not prevent the animal’s ability to respond to stress, it contributed to modulating hippocampal functions in both standard and stressful conditions, notably by shaping the microglial response to chronic stress.","lang":"eng"}],"isi":1},{"file":[{"file_size":4746649,"creator":"bbickel","date_created":"2021-08-24T06:02:15Z","access_level":"open_access","file_id":"9958","relation":"main_file","checksum":"961db0bde76dd87cf833930080bb9f38","date_updated":"2021-08-24T06:02:15Z","content_type":"application/pdf","file_name":"R_Monocular_Reconstruction_of_Neural_Face_Reflectance_Fields_CVPR_2021_paper[1].pdf"}],"date_updated":"2023-08-11T11:08:35Z","department":[{"_id":"BeBi"}],"publication_status":"published","has_accepted_license":"1","type":"conference","date_published":"2021-09-01T00:00:00Z","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","oa_version":"Preprint","date_created":"2021-08-24T06:03:00Z","language":[{"iso":"eng"}],"quality_controlled":"1","arxiv":1,"external_id":{"isi":["000739917304096"],"arxiv":["2008.10247"]},"page":"4791-4800","citation":{"chicago":"B R, Mallikarjun, Ayush Tewari, Tae-Hyun Oh, Tim Weyrich, Bernd Bickel, Hans-Peter Seidel, Hanspeter Pfister, Wojciech Matusik, Mohamed Elgharib, and Christian Theobalt. “Monocular Reconstruction of Neural Face Reflectance Fields.” In <i>Proceedings of the IEEE Computer Society Conference on Computer Vision and Pattern Recognition</i>, 4791–4800. IEEE, 2021. <a href=\"https://doi.org/10.1109/CVPR46437.2021.00476\">https://doi.org/10.1109/CVPR46437.2021.00476</a>.","short":"M. B R, A. Tewari, T.-H. Oh, T. Weyrich, B. Bickel, H.-P. Seidel, H. Pfister, W. Matusik, M. Elgharib, C. Theobalt, in:, Proceedings of the IEEE Computer Society Conference on Computer Vision and Pattern Recognition, IEEE, 2021, pp. 4791–4800.","ieee":"M. B R <i>et al.</i>, “Monocular reconstruction of neural face reflectance fields,” in <i>Proceedings of the IEEE Computer Society Conference on Computer Vision and Pattern Recognition</i>, Nashville, TN, United States; Virtual, 2021, pp. 4791–4800.","mla":"B R, Mallikarjun, et al. “Monocular Reconstruction of Neural Face Reflectance Fields.” <i>Proceedings of the IEEE Computer Society Conference on Computer Vision and Pattern Recognition</i>, IEEE, 2021, pp. 4791–800, doi:<a href=\"https://doi.org/10.1109/CVPR46437.2021.00476\">10.1109/CVPR46437.2021.00476</a>.","apa":"B R, M., Tewari, A., Oh, T.-H., Weyrich, T., Bickel, B., Seidel, H.-P., … Theobalt, C. (2021). Monocular reconstruction of neural face reflectance fields. In <i>Proceedings of the IEEE Computer Society Conference on Computer Vision and Pattern Recognition</i> (pp. 4791–4800). Nashville, TN, United States; Virtual: IEEE. <a href=\"https://doi.org/10.1109/CVPR46437.2021.00476\">https://doi.org/10.1109/CVPR46437.2021.00476</a>","ama":"B R M, Tewari A, Oh T-H, et al. Monocular reconstruction of neural face reflectance fields. In: <i>Proceedings of the IEEE Computer Society Conference on Computer Vision and Pattern Recognition</i>. IEEE; 2021:4791-4800. doi:<a href=\"https://doi.org/10.1109/CVPR46437.2021.00476\">10.1109/CVPR46437.2021.00476</a>","ista":"B R M, Tewari A, Oh T-H, Weyrich T, Bickel B, Seidel H-P, Pfister H, Matusik W, Elgharib M, Theobalt C. 2021. Monocular reconstruction of neural face reflectance fields. Proceedings of the IEEE Computer Society Conference on Computer Vision and Pattern Recognition. CVPR: Conference on Computer Vision and Pattern Recognition, 4791–4800."},"acknowledgement":"We thank Tarun Yenamandra and Duarte David for helping us with the comparisons. This work was supported by the\r\nERC Consolidator Grant 4DReply (770784). We also acknowledge support from InterDigital.","fulldoi":"https://doi.org/10.1109/CVPR46437.2021.00476","ddc":["000"],"publisher":"IEEE","file_date_updated":"2021-08-24T06:02:15Z","doi":"10.1109/CVPR46437.2021.00476","publication_identifier":{"issn":["1063-6919"],"isbn":["978-166544509-2"]},"day":"01","conference":{"start_date":"2021-06-20","name":"CVPR: Conference on Computer Vision and Pattern Recognition","end_date":"2021-06-25","location":"Nashville, TN, United States; Virtual"},"publication":"Proceedings of the IEEE Computer Society Conference on Computer Vision and Pattern Recognition","year":"2021","_id":"9957","status":"public","month":"09","oa":1,"article_processing_charge":"No","title":"Monocular reconstruction of neural face reflectance fields","scopus_import":"1","isi":1,"abstract":[{"lang":"eng","text":"The reflectance field of a face describes the reflectance properties responsible for complex lighting effects including diffuse, specular, inter-reflection and self shadowing. Most existing methods for estimating the face reflectance from a monocular image assume faces to be diffuse with very few approaches adding a specular component. This still leaves out important perceptual aspects of reflectance as higher-order global illumination effects and self-shadowing are not modeled. We present a new neural representation for face reflectance where we can estimate all components of the reflectance responsible for the final appearance from a single monocular image. Instead of modeling each component of the reflectance separately using parametric models, our neural representation allows us to generate a basis set of faces in a geometric deformation-invariant space, parameterized by the input light direction, viewpoint and face geometry. We learn to reconstruct this reflectance field of a face just from a monocular image, which can be used to render the face from any viewpoint in any light condition. Our method is trained on a light-stage training dataset, which captures 300 people illuminated with 150 light conditions from 8 viewpoints. We show that our method outperforms existing monocular reflectance reconstruction methods, in terms of photorealism due to better capturing of physical premitives, such as sub-surface scattering, specularities, self-shadows and other higher-order effects."}],"author":[{"last_name":"B R","full_name":"B R, Mallikarjun","first_name":"Mallikarjun"},{"full_name":"Tewari, Ayush","first_name":"Ayush","last_name":"Tewari"},{"last_name":"Oh","full_name":"Oh, Tae-Hyun","first_name":"Tae-Hyun"},{"last_name":"Weyrich","first_name":"Tim","full_name":"Weyrich, Tim"},{"last_name":"Bickel","full_name":"Bickel, Bernd","id":"49876194-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-6511-9385","first_name":"Bernd"},{"first_name":"Hans-Peter","full_name":"Seidel, Hans-Peter","last_name":"Seidel"},{"first_name":"Hanspeter","full_name":"Pfister, Hanspeter","last_name":"Pfister"},{"full_name":"Matusik, Wojciech","first_name":"Wojciech","last_name":"Matusik"},{"full_name":"Elgharib, Mohamed","first_name":"Mohamed","last_name":"Elgharib"},{"full_name":"Theobalt, Christian","first_name":"Christian","last_name":"Theobalt"}]},{"fulldoi":"https://doi.org/10.1103/PhysRevLett.127.090602","publisher":"American Physical Society","doi":"10.1103/PhysRevLett.127.090602","publication_identifier":{"issn":["0031-9007"],"eissn":["1079-7114"]},"day":"27","publication":"Physical Review Letters","year":"2021","_id":"9960","status":"public","month":"08","oa":1,"article_processing_charge":"No","title":"Discrete time-crystalline order enabled by quantum many-body scars: Entanglement steering via periodic driving","scopus_import":"1","article_number":"090602","isi":1,"abstract":[{"lang":"eng","text":"The control of many-body quantum dynamics in complex systems is a key challenge in the quest to reliably produce and manipulate large-scale quantum entangled states. Recently, quench experiments in Rydberg atom arrays [Bluvstein et al. Science 371, 1355 (2021)] demonstrated that coherent revivals associated with quantum many-body scars can be stabilized by periodic driving, generating stable subharmonic responses over a wide parameter regime. We analyze a simple, related model where these phenomena originate from spatiotemporal ordering in an effective Floquet unitary, corresponding to discrete time-crystalline behavior in a prethermal regime. Unlike conventional discrete time crystals, the subharmonic response exists only for Néel-like initial states, associated with quantum scars. We predict robustness to perturbations and identify emergent timescales that could be observed in future experiments. Our results suggest a route to controlling entanglement in interacting quantum systems by combining periodic driving with many-body scars."}],"author":[{"first_name":"N.","full_name":"Maskara, N.","last_name":"Maskara"},{"id":"36EBAD38-F248-11E8-B48F-1D18A9856A87","full_name":"Michailidis, Alexios","first_name":"Alexios","orcid":"0000-0002-8443-1064","last_name":"Michailidis"},{"full_name":"Ho, W. W.","first_name":"W. W.","last_name":"Ho"},{"last_name":"Bluvstein","full_name":"Bluvstein, D.","first_name":"D."},{"last_name":"Choi","first_name":"S.","full_name":"Choi, S."},{"last_name":"Lukin","first_name":"M. D.","full_name":"Lukin, M. D."},{"orcid":"0000-0002-2399-5827","first_name":"Maksym","id":"47809E7E-F248-11E8-B48F-1D18A9856A87","full_name":"Serbyn, Maksym","last_name":"Serbyn"}],"article_type":"letter_note","date_updated":"2025-04-14T07:52:05Z","publication_status":"published","department":[{"_id":"MaSe"}],"type":"journal_article","date_published":"2021-08-27T00:00:00Z","oa_version":"Submitted Version","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","date_created":"2021-08-28T08:08:58Z","language":[{"iso":"eng"}],"arxiv":1,"quality_controlled":"1","intvolume":"       127","external_id":{"arxiv":["2102.13160"],"isi":["000692200100002"]},"citation":{"chicago":"Maskara, N., Alexios Michailidis, W. W. Ho, D. Bluvstein, S. Choi, M. D. Lukin, and Maksym Serbyn. “Discrete Time-Crystalline Order Enabled by Quantum Many-Body Scars: Entanglement Steering via Periodic Driving.” <i>Physical Review Letters</i>. American Physical Society, 2021. <a href=\"https://doi.org/10.1103/PhysRevLett.127.090602\">https://doi.org/10.1103/PhysRevLett.127.090602</a>.","ieee":"N. Maskara <i>et al.</i>, “Discrete time-crystalline order enabled by quantum many-body scars: Entanglement steering via periodic driving,” <i>Physical Review Letters</i>, vol. 127, no. 9. American Physical Society, 2021.","short":"N. Maskara, A. Michailidis, W.W. Ho, D. Bluvstein, S. Choi, M.D. Lukin, M. Serbyn, Physical Review Letters 127 (2021).","ama":"Maskara N, Michailidis A, Ho WW, et al. Discrete time-crystalline order enabled by quantum many-body scars: Entanglement steering via periodic driving. <i>Physical Review Letters</i>. 2021;127(9). doi:<a href=\"https://doi.org/10.1103/PhysRevLett.127.090602\">10.1103/PhysRevLett.127.090602</a>","ista":"Maskara N, Michailidis A, Ho WW, Bluvstein D, Choi S, Lukin MD, Serbyn M. 2021. Discrete time-crystalline order enabled by quantum many-body scars: Entanglement steering via periodic driving. Physical Review Letters. 127(9), 090602.","apa":"Maskara, N., Michailidis, A., Ho, W. W., Bluvstein, D., Choi, S., Lukin, M. D., &#38; Serbyn, M. (2021). Discrete time-crystalline order enabled by quantum many-body scars: Entanglement steering via periodic driving. <i>Physical Review Letters</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevLett.127.090602\">https://doi.org/10.1103/PhysRevLett.127.090602</a>","mla":"Maskara, N., et al. “Discrete Time-Crystalline Order Enabled by Quantum Many-Body Scars: Entanglement Steering via Periodic Driving.” <i>Physical Review Letters</i>, vol. 127, no. 9, 090602, American Physical Society, 2021, doi:<a href=\"https://doi.org/10.1103/PhysRevLett.127.090602\">10.1103/PhysRevLett.127.090602</a>."},"main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/2102.13160"}],"issue":"9","ec_funded":1,"volume":127,"acknowledgement":"We thank Dmitry Abanin, Ehud Altman, Iris Cong, Sepehr Ebadi, Alex Keesling, Harry Levine, Ahmed Omran, Hannes Pichler, Rhine Samajdar, Guilia Semeghini, Tout Wang, Norman Yao, and Harry Zhou or stimulating discussions. We acknowledge support from the Center for Ultracold Atoms, the National Science Foundation, the Vannevar Bush Faculty Fellowship, the U.S. Department of Energy, the Army Research Office MURI, and the DARPA ONISQ program (M. L., N. M, W. W. H., D. B.); the European Research Council (ERC) under the European Union’s Horizon 2020 Research and Innovation Programme Grant Agreement No. 850899 (A. M. and M. S.); the Department of Energy Computational Science Graduate Fellowship under Awards No. DESC0021110 (N. M.); the Moore Foundation EPiQS initiative Grant No. GBMF4306, the National University of Singapore (NUS) Development Grant AY2019/2020 and the Stanford Institute for Theoretical Physics (W. W. H.); the NSF Graduate Research Fellowship Program (Grant No. DGE1745303) and The Fannie and John Hertz Foundation (D. B.); the Miller Institute for Basic Research in Science (S. C.); DOE Quantum Systems Accelerator – Contract No. 7568717; and DOE Programmable Quantum Simulators for Lattice Gauge Theories and Gauge-Gravity Correspondence – Grant No. DE-SC0021013.","project":[{"grant_number":"850899","name":"Non-Ergodic Quantum Matter: Universality, Dynamics and Control","_id":"23841C26-32DE-11EA-91FC-C7463DDC885E","call_identifier":"H2020"}]},{"publication_status":"published","department":[{"_id":"MaSe"}],"date_updated":"2025-04-14T07:52:05Z","article_type":"letter_note","intvolume":"       104","arxiv":1,"quality_controlled":"1","language":[{"iso":"eng"}],"oa_version":"Submitted Version","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","date_created":"2021-08-28T16:44:55Z","date_published":"2021-08-15T00:00:00Z","type":"journal_article","ec_funded":1,"issue":"8","main_file_link":[{"url":"https://arxiv.org/abs/2012.15676","open_access":"1"}],"citation":{"chicago":"Sonner, Michael, Maksym Serbyn, Zlatko Papić, and Dmitry A. Abanin. “Thouless Energy across the Many-Body Localization Transition in Floquet Systems.” <i>Physical Review B</i>. American Physical Society, 2021. <a href=\"https://doi.org/10.1103/PhysRevB.104.L081112\">https://doi.org/10.1103/PhysRevB.104.L081112</a>.","ieee":"M. Sonner, M. Serbyn, Z. Papić, and D. A. Abanin, “Thouless energy across the many-body localization transition in Floquet systems,” <i>Physical Review B</i>, vol. 104, no. 8. American Physical Society, 2021.","short":"M. Sonner, M. Serbyn, Z. Papić, D.A. Abanin, Physical Review B 104 (2021).","ista":"Sonner M, Serbyn M, Papić Z, Abanin DA. 2021. Thouless energy across the many-body localization transition in Floquet systems. Physical Review B. 104(8), L081112.","ama":"Sonner M, Serbyn M, Papić Z, Abanin DA. Thouless energy across the many-body localization transition in Floquet systems. <i>Physical Review B</i>. 2021;104(8). doi:<a href=\"https://doi.org/10.1103/PhysRevB.104.L081112\">10.1103/PhysRevB.104.L081112</a>","apa":"Sonner, M., Serbyn, M., Papić, Z., &#38; Abanin, D. A. (2021). Thouless energy across the many-body localization transition in Floquet systems. <i>Physical Review B</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevB.104.L081112\">https://doi.org/10.1103/PhysRevB.104.L081112</a>","mla":"Sonner, Michael, et al. “Thouless Energy across the Many-Body Localization Transition in Floquet Systems.” <i>Physical Review B</i>, vol. 104, no. 8, L081112, American Physical Society, 2021, doi:<a href=\"https://doi.org/10.1103/PhysRevB.104.L081112\">10.1103/PhysRevB.104.L081112</a>."},"external_id":{"isi":["000689734500009"],"arxiv":["2012.15676"]},"project":[{"call_identifier":"H2020","grant_number":"850899","name":"Non-Ergodic Quantum Matter: Universality, Dynamics and Control","_id":"23841C26-32DE-11EA-91FC-C7463DDC885E"}],"volume":104,"acknowledgement":"We thank S. Garratt for useful comments on the manuscript. This work was supported by the Swiss National Science Foundation (M. Sonner and D.A.A.) and by the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (M. Serbyn, Grant Agreement No. 850899, and D.A.A., Grant Agreement No. 864597). Z.P. acknowledges support from EPSRC Grant No. EP/R020612/1 and from Leverhulme Trust Research Leadership Award No. RL-2019-015. The computations were performed on the Baobab cluster of the University\r\nof Geneva.","day":"15","publication_identifier":{"eissn":["2469-9969"],"issn":["2469-9950"]},"doi":"10.1103/PhysRevB.104.L081112","publisher":"American Physical Society","fulldoi":"https://doi.org/10.1103/PhysRevB.104.L081112","scopus_import":"1","title":"Thouless energy across the many-body localization transition in Floquet systems","article_processing_charge":"No","oa":1,"status":"public","_id":"9961","month":"08","year":"2021","publication":"Physical Review B","isi":1,"article_number":"L081112","author":[{"first_name":"Michael","full_name":"Sonner, Michael","last_name":"Sonner"},{"last_name":"Serbyn","id":"47809E7E-F248-11E8-B48F-1D18A9856A87","full_name":"Serbyn, Maksym","first_name":"Maksym","orcid":"0000-0002-2399-5827"},{"first_name":"Zlatko","full_name":"Papić, Zlatko","last_name":"Papić"},{"full_name":"Abanin, Dmitry A.","first_name":"Dmitry A.","last_name":"Abanin"}],"abstract":[{"text":"The notion of Thouless energy plays a central role in the theory of Anderson localization. We investigate and compare the scaling of Thouless energy across the many-body localization (MBL) transition in a Floquet model. We use a combination of methods that are reliable on the ergodic side of the transition (e.g., spectral form factor) and methods that work on the MBL side (e.g., typical matrix elements of local operators) to obtain a complete picture of the Thouless energy behavior across the transition. On the ergodic side, Thouless energy decreases slowly with the system size, while at the transition it becomes comparable to the level spacing. Different probes yield consistent estimates of Thouless energy in their overlapping regime of applicability, giving the location of the transition point nearly free of finite-size drift. This work establishes a connection between different definitions of Thouless energy in a many-body setting and yields insights into the MBL transition in Floquet systems.","lang":"eng"}]},{"project":[{"name":"Teaching Old Crypto New Tricks","grant_number":"682815","_id":"258AA5B2-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"}],"citation":{"mla":"Pietrzak, Krzysztof Z., et al. <i>LightPIR: Privacy-Preserving Route Discovery for Payment Channel Networks</i>. IEEE, 2021, doi:<a href=\"https://doi.org/10.23919/IFIPNetworking52078.2021.9472205\">10.23919/IFIPNetworking52078.2021.9472205</a>.","apa":"Pietrzak, K. Z., Salem, I., Schmid, S., &#38; Yeo, M. X. (2021). LightPIR: Privacy-preserving route discovery for payment channel networks. Presented at the 2021 IFIP Networking Conference (IFIP Networking), Espoo and Helsinki, Finland: IEEE. <a href=\"https://doi.org/10.23919/IFIPNetworking52078.2021.9472205\">https://doi.org/10.23919/IFIPNetworking52078.2021.9472205</a>","ista":"Pietrzak KZ, Salem I, Schmid S, Yeo MX. 2021. LightPIR: Privacy-preserving route discovery for payment channel networks. 2021 IFIP Networking Conference (IFIP Networking).","ama":"Pietrzak KZ, Salem I, Schmid S, Yeo MX. LightPIR: Privacy-preserving route discovery for payment channel networks. In: IEEE; 2021. doi:<a href=\"https://doi.org/10.23919/IFIPNetworking52078.2021.9472205\">10.23919/IFIPNetworking52078.2021.9472205</a>","short":"K.Z. Pietrzak, I. Salem, S. Schmid, M.X. Yeo, in:, IEEE, 2021.","ieee":"K. Z. Pietrzak, I. Salem, S. Schmid, and M. X. Yeo, “LightPIR: Privacy-preserving route discovery for payment channel networks,” presented at the 2021 IFIP Networking Conference (IFIP Networking), Espoo and Helsinki, Finland, 2021.","chicago":"Pietrzak, Krzysztof Z, Iosif Salem, Stefan Schmid, and Michelle X Yeo. “LightPIR: Privacy-Preserving Route Discovery for Payment Channel Networks.” IEEE, 2021. <a href=\"https://doi.org/10.23919/IFIPNetworking52078.2021.9472205\">https://doi.org/10.23919/IFIPNetworking52078.2021.9472205</a>."},"external_id":{"isi":["000853016800008"],"arxiv":["2104.04293"]},"main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/2104.04293"}],"ec_funded":1,"type":"conference","date_published":"2021-06-21T00:00:00Z","language":[{"iso":"eng"}],"date_created":"2021-08-29T22:01:16Z","oa_version":"Submitted Version","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","quality_controlled":"1","arxiv":1,"date_updated":"2026-04-07T13:29:44Z","department":[{"_id":"KrPi"}],"publication_status":"published","abstract":[{"text":"Payment channel networks are a promising approach to improve the scalability of cryptocurrencies: they allow to perform transactions in a peer-to-peer fashion, along multihop routes in the network, without requiring consensus on the blockchain. However, during the discovery of cost-efficient routes for the transaction, critical information may be revealed about the transacting entities. This paper initiates the study of privacy-preserving route discovery mechanisms for payment channel networks. In particular, we present LightPIR, an approach which allows a client to learn the shortest (or cheapest in terms of fees) path between two nodes without revealing any information about the endpoints of the transaction to the servers. The two main observations which allow for an efficient solution in LightPIR are that: (1) surprisingly, hub labelling algorithms – which were developed to preprocess “street network like” graphs so one can later efficiently compute shortest paths – also perform well for the graphs underlying payment channel networks, and that (2) hub labelling algorithms can be conveniently combined with private information retrieval. LightPIR relies on a simple hub labeling heuristic on top of existing hub labeling algorithms which leverages the specific topological features of cryptocurrency networks to further minimize storage and bandwidth overheads. In a case study considering the Lightning network, we show that our approach is an order of magnitude more efficient compared to a privacy-preserving baseline based on using private information retrieval on a database that stores all pairs shortest paths.","lang":"eng"}],"related_material":{"record":[{"id":"14506","relation":"dissertation_contains","status":"public"}]},"author":[{"first_name":"Krzysztof Z","orcid":"0000-0002-9139-1654","id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87","full_name":"Pietrzak, Krzysztof Z","last_name":"Pietrzak"},{"first_name":"Iosif","full_name":"Salem, Iosif","last_name":"Salem"},{"last_name":"Schmid","full_name":"Schmid, Stefan","first_name":"Stefan"},{"last_name":"Yeo","full_name":"Yeo, Michelle X","id":"2D82B818-F248-11E8-B48F-1D18A9856A87","orcid":"0009-0001-3676-4809","first_name":"Michelle X"}],"isi":1,"conference":{"location":"Espoo and Helsinki, Finland","end_date":"2021-06-24","name":"2021 IFIP Networking Conference (IFIP Networking)","start_date":"2021-06-21"},"status":"public","_id":"9969","month":"06","year":"2021","article_processing_charge":"No","oa":1,"scopus_import":"1","title":"LightPIR: Privacy-preserving route discovery for payment channel networks","fulldoi":"https://doi.org/10.23919/IFIPNetworking52078.2021.9472205","doi":"10.23919/IFIPNetworking52078.2021.9472205","publisher":"IEEE","publication_identifier":{"eissn":["1861-2288"],"eisbn":["978-3-9031-7639-3"],"isbn":["978-1-6654-4501-6"]},"day":"21"},{"publication_status":"published","department":[{"_id":"JaMa"}],"date_updated":"2025-06-12T06:30:13Z","article_type":"original","file":[{"access_level":"open_access","date_created":"2021-09-08T07:34:24Z","file_size":505971,"creator":"cchlebak","content_type":"application/pdf","file_name":"2021_CommunMathPhys_Wirth.pdf","date_updated":"2021-09-08T09:46:34Z","file_id":"9990","checksum":"8a602f916b1c2b0dc1159708b7cb204b","relation":"main_file"}],"tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"arxiv":1,"intvolume":"       387","quality_controlled":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","date_created":"2021-08-30T10:07:44Z","language":[{"iso":"eng"}],"date_published":"2021-08-30T00:00:00Z","has_accepted_license":"1","type":"journal_article","ec_funded":1,"external_id":{"pmid":["34776525"],"arxiv":["2007.13506"],"isi":["000691214200001"]},"page":"761–791","citation":{"ista":"Wirth M, Zhang H. 2021. Complete gradient estimates of quantum Markov semigroups. Communications in Mathematical Physics. 387, 761–791.","ama":"Wirth M, Zhang H. Complete gradient estimates of quantum Markov semigroups. <i>Communications in Mathematical Physics</i>. 2021;387:761–791. doi:<a href=\"https://doi.org/10.1007/s00220-021-04199-4\">10.1007/s00220-021-04199-4</a>","mla":"Wirth, Melchior, and Haonan Zhang. “Complete Gradient Estimates of Quantum Markov Semigroups.” <i>Communications in Mathematical Physics</i>, vol. 387, Springer Nature, 2021, pp. 761–791, doi:<a href=\"https://doi.org/10.1007/s00220-021-04199-4\">10.1007/s00220-021-04199-4</a>.","apa":"Wirth, M., &#38; Zhang, H. (2021). Complete gradient estimates of quantum Markov semigroups. <i>Communications in Mathematical Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00220-021-04199-4\">https://doi.org/10.1007/s00220-021-04199-4</a>","ieee":"M. Wirth and H. Zhang, “Complete gradient estimates of quantum Markov semigroups,” <i>Communications in Mathematical Physics</i>, vol. 387. Springer Nature, pp. 761–791, 2021.","short":"M. Wirth, H. Zhang, Communications in Mathematical Physics 387 (2021) 761–791.","chicago":"Wirth, Melchior, and Haonan Zhang. “Complete Gradient Estimates of Quantum Markov Semigroups.” <i>Communications in Mathematical Physics</i>. Springer Nature, 2021. <a href=\"https://doi.org/10.1007/s00220-021-04199-4\">https://doi.org/10.1007/s00220-021-04199-4</a>."},"project":[{"_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854","name":"IST Austria Open Access Fund"},{"call_identifier":"H2020","name":"ISTplus - Postdoctoral Fellowships","grant_number":"754411","_id":"260C2330-B435-11E9-9278-68D0E5697425"},{"name":"Taming Complexity in Partial Differential Systems","grant_number":"F6504","_id":"fc31cba2-9c52-11eb-aca3-ff467d239cd2"}],"acknowledgement":"Both authors would like to thank Jan Maas for fruitful discussions and helpful comments.","volume":387,"day":"30","publication_identifier":{"issn":["0010-3616"],"eissn":["1432-0916"]},"publisher":"Springer Nature","file_date_updated":"2021-09-08T09:46:34Z","doi":"10.1007/s00220-021-04199-4","ddc":["621"],"fulldoi":"https://doi.org/10.1007/s00220-021-04199-4","title":"Complete gradient estimates of quantum Markov semigroups","scopus_import":"1","oa":1,"article_processing_charge":"Yes (via OA deal)","year":"2021","status":"public","_id":"9973","month":"08","publication":"Communications in Mathematical Physics","isi":1,"corr_author":"1","keyword":["Mathematical Physics","Statistical and Nonlinear Physics"],"author":[{"full_name":"Wirth, Melchior","id":"88644358-0A0E-11EA-8FA5-49A33DDC885E","orcid":"0000-0002-0519-4241","first_name":"Melchior","last_name":"Wirth"},{"last_name":"Zhang","id":"D8F41E38-9E66-11E9-A9E2-65C2E5697425","full_name":"Zhang, Haonan","first_name":"Haonan"}],"pmid":1,"abstract":[{"text":"In this article we introduce a complete gradient estimate for symmetric quantum Markov semigroups on von Neumann algebras equipped with a normal faithful tracial state, which implies semi-convexity of the entropy with respect to the recently introduced noncommutative 2-Wasserstein distance. We show that this complete gradient estimate is stable under tensor products and free products and establish its validity for a number of examples. As an application we prove a complete modified logarithmic Sobolev inequality with optimal constant for Poisson-type semigroups on free group factors.","lang":"eng"}]},{"corr_author":"1","keyword":["Catalysis","Energy engineering","Materials theory and modeling"],"related_material":{"record":[{"status":"public","relation":"later_version","id":"10813"}]},"abstract":[{"text":"Redox mediators could catalyse otherwise slow and energy-inefficient cycling of Li-S and Li-O 2 batteries by shuttling electrons/holes between the electrode and the solid insulating storage materials. For mediators to work efficiently they need to oxidize the solid with fast kinetics yet the lowest possible overpotential. Here, we found that when the redox potentials of mediators are tuned via, e.g., Li + concentration in the electrolyte, they exhibit distinct threshold potentials, where the kinetics accelerate several-fold within a range as small as 10 mV. This phenomenon is independent of types of mediators and electrolyte. The acceleration originates from the overpotentials required to activate fast Li + /e – extraction and the following chemical step at specific abundant surface facets. Efficient redox catalysis at insulating solids requires therefore carefully considering the surface conditions of the storage materials and electrolyte-dependent redox potentials, which may be tuned by salt concentrations or solvents.","lang":"eng"}],"author":[{"first_name":"Deqing","full_name":"Cao, Deqing","last_name":"Cao"},{"full_name":"Shen, Xiaoxiao","first_name":"Xiaoxiao","last_name":"Shen"},{"full_name":"Wang, Aiping","first_name":"Aiping","last_name":"Wang"},{"last_name":"Yu","full_name":"Yu, Fengjiao","first_name":"Fengjiao"},{"last_name":"Wu","first_name":"Yuping","full_name":"Wu, Yuping"},{"first_name":"Siqi","full_name":"Shi, Siqi","last_name":"Shi"},{"last_name":"Freunberger","orcid":"0000-0003-2902-5319","first_name":"Stefan Alexander","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425","full_name":"Freunberger, Stefan Alexander"},{"first_name":"Yuhui","full_name":"Chen, Yuhui","last_name":"Chen"}],"file_date_updated":"2021-08-31T14:02:19Z","doi":"10.21203/rs.3.rs-750965/v1","publisher":"Research Square","ddc":["541"],"fulldoi":"https://doi.org/10.21203/rs.3.rs-750965/v1","day":"18","publication_identifier":{"eissn":["2693-5015"]},"status":"public","_id":"9978","month":"08","year":"2021","publication":"Research Square","title":"Sharp kinetic acceleration potentials during mediated redox catalysis of insulators","article_processing_charge":"No","oa":1,"citation":{"short":"D. Cao, X. Shen, A. Wang, F. Yu, Y. Wu, S. Shi, S.A. Freunberger, Y. Chen, Research Square (n.d.).","ieee":"D. Cao <i>et al.</i>, “Sharp kinetic acceleration potentials during mediated redox catalysis of insulators,” <i>Research Square</i>. Research Square.","apa":"Cao, D., Shen, X., Wang, A., Yu, F., Wu, Y., Shi, S., … Chen, Y. (n.d.). Sharp kinetic acceleration potentials during mediated redox catalysis of insulators. <i>Research Square</i>. Research Square. <a href=\"https://doi.org/10.21203/rs.3.rs-750965/v1\">https://doi.org/10.21203/rs.3.rs-750965/v1</a>","mla":"Cao, Deqing, et al. “Sharp Kinetic Acceleration Potentials during Mediated Redox Catalysis of Insulators.” <i>Research Square</i>, Research Square, doi:<a href=\"https://doi.org/10.21203/rs.3.rs-750965/v1\">10.21203/rs.3.rs-750965/v1</a>.","ama":"Cao D, Shen X, Wang A, et al. Sharp kinetic acceleration potentials during mediated redox catalysis of insulators. <i>Research Square</i>. doi:<a href=\"https://doi.org/10.21203/rs.3.rs-750965/v1\">10.21203/rs.3.rs-750965/v1</a>","ista":"Cao D, Shen X, Wang A, Yu F, Wu Y, Shi S, Freunberger SA, Chen Y. Sharp kinetic acceleration potentials during mediated redox catalysis of insulators. Research Square, <a href=\"https://doi.org/10.21203/rs.3.rs-750965/v1\">10.21203/rs.3.rs-750965/v1</a>.","chicago":"Cao, Deqing, Xiaoxiao Shen, Aiping Wang, Fengjiao Yu, Yuping Wu, Siqi Shi, Stefan Alexander Freunberger, and Yuhui Chen. “Sharp Kinetic Acceleration Potentials during Mediated Redox Catalysis of Insulators.” <i>Research Square</i>. Research Square, n.d. <a href=\"https://doi.org/10.21203/rs.3.rs-750965/v1\">https://doi.org/10.21203/rs.3.rs-750965/v1</a>."},"page":"21","acknowledgement":"This work was financially supported by the National Natural Science Foundation of China (51773092, 21975124, 11874254, 51802187, U2030206). S.A.F. is indebted to IST Austria for support. ","tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"file":[{"relation":"main_file","checksum":"1878e91c29d5769ed5a827b0b7addf00","file_id":"9979","date_updated":"2021-08-31T14:02:19Z","success":1,"file_name":"2021_ResearchSquare_Cao.pdf","content_type":"application/pdf","creator":"cchlebak","file_size":1019662,"date_created":"2021-08-31T14:02:19Z","access_level":"open_access"}],"department":[{"_id":"StFr"}],"publication_status":"submitted","date_updated":"2024-10-09T21:01:46Z","date_published":"2021-08-18T00:00:00Z","type":"preprint","has_accepted_license":"1","language":[{"iso":"eng"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Preprint","date_created":"2021-08-31T12:54:16Z"},{"acknowledgement":"This project has received funding from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant NanoEvolution, grant agreement No 894042. The authors acknowledge TU Graz for support through the Lead Project LP-03. Likewise, the use of SOMAPP Lab, a core facility supported by the Austrian Federal Ministry of Education, Science and Research, the Graz University\r\n6 of Technology, the University of Graz, and Anton Paar GmbH is acknowledged. S.D.T, A.V. and R.D. acknowledge the financial support by the Slovenian Research Agency (ARRS) research core funding P2-0393. Furthermore, A.V. acknowledge the funding from the Slovenian Research Agency, research project Z2-1863. S.A.F. is indebted to IST Austria for support. ","author":[{"last_name":"Prehal","first_name":"Christian","full_name":"Prehal, Christian"},{"last_name":"Talian","full_name":"Talian, Sara Drvarič","first_name":"Sara Drvarič"},{"full_name":"Vizintin, Alen","first_name":"Alen","last_name":"Vizintin"},{"last_name":"Amenitsch","full_name":"Amenitsch, Heinz","first_name":"Heinz"},{"last_name":"Dominko","first_name":"Robert","full_name":"Dominko, Robert"},{"last_name":"Freunberger","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425","full_name":"Freunberger, Stefan Alexander","first_name":"Stefan Alexander","orcid":"0000-0003-2902-5319"},{"first_name":"Vanessa","full_name":"Wood, Vanessa","last_name":"Wood"}],"abstract":[{"text":"Insufficient understanding of the mechanism that reversibly converts sulphur into lithium sulphide (Li2S) via soluble polysulphides (PS) hampers the realization of high performance lithium-sulphur cells. Typically Li2S formation is explained by direct electroreduction of a PS to Li2S; however, this is not consistent with the size of the insulating Li2S deposits. Here, we use in situ small and wide angle X-ray scattering (SAXS/WAXS) to track the growth and dissolution of crystalline and amorphous deposits from atomic to sub-micron scales during charge and discharge. Stochastic modelling based on the SAXS data allows quantification of the chemical phase evolution during discharge and charge. We show that Li2S deposits predominantly via disproportionation of transient, solid Li2S2 to form primary Li2S crystallites and solid Li2S4 particles. We further demonstrate that this process happens in reverse during charge. These findings show that the discharge capacity and rate capability in Li-S battery cathodes are therefore limited by mass transport through the increasingly tortuous network of Li2S / Li2S4 / carbon pores rather than electron transport through a passivating surface film.","lang":"eng"}],"keyword":["Li2S","Lithium Sulphur Batteries","SAXS","WAXS"],"citation":{"mla":"Prehal, Christian, et al. “Mechanism of Li2S Formation and Dissolution in Lithium-Sulphur Batteries.” <i>Research Square</i>, doi:<a href=\"https://doi.org/10.21203/rs.3.rs-818607/v1\">10.21203/rs.3.rs-818607/v1</a>.","apa":"Prehal, C., Talian, S. D., Vizintin, A., Amenitsch, H., Dominko, R., Freunberger, S. A., &#38; Wood, V. (n.d.). Mechanism of Li2S formation and dissolution in Lithium-Sulphur batteries. <i>Research Square</i>. <a href=\"https://doi.org/10.21203/rs.3.rs-818607/v1\">https://doi.org/10.21203/rs.3.rs-818607/v1</a>","ista":"Prehal C, Talian SD, Vizintin A, Amenitsch H, Dominko R, Freunberger SA, Wood V. Mechanism of Li2S formation and dissolution in Lithium-Sulphur batteries. Research Square, <a href=\"https://doi.org/10.21203/rs.3.rs-818607/v1\">10.21203/rs.3.rs-818607/v1</a>.","ama":"Prehal C, Talian SD, Vizintin A, et al. Mechanism of Li2S formation and dissolution in Lithium-Sulphur batteries. <i>Research Square</i>. doi:<a href=\"https://doi.org/10.21203/rs.3.rs-818607/v1\">10.21203/rs.3.rs-818607/v1</a>","short":"C. Prehal, S.D. Talian, A. Vizintin, H. Amenitsch, R. Dominko, S.A. Freunberger, V. Wood, Research Square (n.d.).","ieee":"C. Prehal <i>et al.</i>, “Mechanism of Li2S formation and dissolution in Lithium-Sulphur batteries,” <i>Research Square</i>. .","chicago":"Prehal, Christian, Sara Drvarič Talian, Alen Vizintin, Heinz Amenitsch, Robert Dominko, Stefan Alexander Freunberger, and Vanessa Wood. “Mechanism of Li2S Formation and Dissolution in Lithium-Sulphur Batteries.” <i>Research Square</i>, n.d. <a href=\"https://doi.org/10.21203/rs.3.rs-818607/v1\">https://doi.org/10.21203/rs.3.rs-818607/v1</a>."},"page":"21","main_file_link":[{"open_access":"1","url":"https://www.researchsquare.com/article/rs-818607/v1"}],"language":[{"iso":"eng"}],"article_processing_charge":"No","date_created":"2021-09-02T08:45:00Z","oa_version":"Preprint","oa":1,"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","title":"Mechanism of Li2S formation and dissolution in Lithium-Sulphur batteries","type":"preprint","publication":"Research Square","_id":"9980","month":"08","date_published":"2021-08-16T00:00:00Z","status":"public","year":"2021","date_updated":"2021-12-03T10:35:42Z","department":[{"_id":"StFr"}],"day":"16","publication_status":"submitted","tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"fulldoi":"https://doi.org/10.21203/rs.3.rs-818607/v1","ddc":["621"],"doi":"10.21203/rs.3.rs-818607/v1"},{"title":"Importance sampling scheme for the stochastic simulation of quantum spin dynamics","scopus_import":"1","oa":1,"article_processing_charge":"No","year":"2021","_id":"9981","month":"09","status":"public","publication":"SciPost Physics","day":"02","publication_identifier":{"issn":["2542-4653"],"eissn":["2666-9366"]},"publisher":"SciPost Foundation","file_date_updated":"2021-09-02T14:05:43Z","doi":"10.21468/scipostphys.11.3.048","fulldoi":"https://doi.org/10.21468/scipostphys.11.3.048","ddc":["519"],"author":[{"full_name":"De Nicola, Stefano","id":"42832B76-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-4842-6671","first_name":"Stefano","last_name":"De Nicola"}],"abstract":[{"lang":"eng","text":"The numerical simulation of dynamical phenomena in interacting quantum systems is a notoriously hard problem. Although a number of promising numerical methods exist, they often have limited applicability due to the growth of entanglement or the presence of the so-called sign problem. In this work, we develop an importance sampling scheme for the simulation of quantum spin dynamics, building on a recent approach mapping quantum spin systems to classical stochastic processes. The importance sampling scheme is based on identifying the classical trajectory that yields the largest contribution to a given quantum observable. An exact transformation is then carried out to preferentially sample trajectories that are close to the dominant one. We demonstrate that this approach is capable of reducing the temporal growth of fluctuations in the stochastic quantities, thus extending the range of accessible times and system sizes compared to direct sampling. We discuss advantages and limitations of the proposed approach, outlining directions\r\nfor further developments."}],"article_number":"048","isi":1,"keyword":["General Physics and Astronomy"],"arxiv":1,"intvolume":"        11","quality_controlled":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","date_created":"2021-09-02T11:49:47Z","language":[{"iso":"eng"}],"date_published":"2021-09-02T00:00:00Z","has_accepted_license":"1","type":"journal_article","publication_status":"published","department":[{"_id":"MaSe"}],"date_updated":"2025-05-14T10:51:45Z","article_type":"original","file":[{"file_name":"2021_SciPostPhys_DeNicola.pdf","content_type":"application/pdf","success":1,"date_updated":"2021-09-02T14:05:43Z","relation":"main_file","checksum":"e4ec69d893e31811efc6093cb6ea8eb7","file_id":"9984","access_level":"open_access","date_created":"2021-09-02T14:05:43Z","creator":"cchlebak","file_size":373833}],"tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"project":[{"grant_number":"754411","name":"ISTplus - Postdoctoral Fellowships","_id":"260C2330-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"}],"volume":11,"ec_funded":1,"issue":"3","external_id":{"isi":["000692534200001"],"arxiv":["2103.16468"]},"citation":{"chicago":"De Nicola, Stefano. “Importance Sampling Scheme for the Stochastic Simulation of Quantum Spin Dynamics.” <i>SciPost Physics</i>. SciPost Foundation, 2021. <a href=\"https://doi.org/10.21468/scipostphys.11.3.048\">https://doi.org/10.21468/scipostphys.11.3.048</a>.","apa":"De Nicola, S. (2021). Importance sampling scheme for the stochastic simulation of quantum spin dynamics. <i>SciPost Physics</i>. SciPost Foundation. <a href=\"https://doi.org/10.21468/scipostphys.11.3.048\">https://doi.org/10.21468/scipostphys.11.3.048</a>","mla":"De Nicola, Stefano. “Importance Sampling Scheme for the Stochastic Simulation of Quantum Spin Dynamics.” <i>SciPost Physics</i>, vol. 11, no. 3, 048, SciPost Foundation, 2021, doi:<a href=\"https://doi.org/10.21468/scipostphys.11.3.048\">10.21468/scipostphys.11.3.048</a>.","ama":"De Nicola S. Importance sampling scheme for the stochastic simulation of quantum spin dynamics. <i>SciPost Physics</i>. 2021;11(3). doi:<a href=\"https://doi.org/10.21468/scipostphys.11.3.048\">10.21468/scipostphys.11.3.048</a>","ista":"De Nicola S. 2021. Importance sampling scheme for the stochastic simulation of quantum spin dynamics. SciPost Physics. 11(3), 048.","short":"S. De Nicola, SciPost Physics 11 (2021).","ieee":"S. De Nicola, “Importance sampling scheme for the stochastic simulation of quantum spin dynamics,” <i>SciPost Physics</i>, vol. 11, no. 3. SciPost Foundation, 2021."}},{"issue":"1","citation":{"short":"J. Watson, A. Pinggera, H. Ho, I.H. Greger, Nature Communications 12 (2021).","ieee":"J. Watson, A. Pinggera, H. Ho, and I. H. Greger, “AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP γ8 interactions,” <i>Nature Communications</i>, vol. 12, no. 1. Nature Publishing Group, 2021.","mla":"Watson, Jake, et al. “AMPA Receptor Anchoring at CA1 Synapses Is Determined by N-Terminal Domain and TARP Γ8 Interactions.” <i>Nature Communications</i>, vol. 12, no. 1, 5083, Nature Publishing Group, 2021, doi:<a href=\"https://doi.org/10.1038/s41467-021-25281-4\">10.1038/s41467-021-25281-4</a>.","apa":"Watson, J., Pinggera, A., Ho, H., &#38; Greger, I. H. (2021). AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP γ8 interactions. <i>Nature Communications</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/s41467-021-25281-4\">https://doi.org/10.1038/s41467-021-25281-4</a>","ista":"Watson J, Pinggera A, Ho H, Greger IH. 2021. AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP γ8 interactions. Nature Communications. 12(1), 5083.","ama":"Watson J, Pinggera A, Ho H, Greger IH. AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP γ8 interactions. <i>Nature Communications</i>. 2021;12(1). doi:<a href=\"https://doi.org/10.1038/s41467-021-25281-4\">10.1038/s41467-021-25281-4</a>","chicago":"Watson, Jake, Alexandra Pinggera, Hinze Ho, and Ingo H. Greger. “AMPA Receptor Anchoring at CA1 Synapses Is Determined by N-Terminal Domain and TARP Γ8 Interactions.” <i>Nature Communications</i>. Nature Publishing Group, 2021. <a href=\"https://doi.org/10.1038/s41467-021-25281-4\">https://doi.org/10.1038/s41467-021-25281-4</a>."},"external_id":{"pmid":["34426577 "],"isi":["000687672000006"]},"volume":12,"acknowledgement":"The authors are very grateful to Andrew Penn for advice and discussions on surface receptor labelling in slice tissue, dissociated culture transfection, and for providing tdTomato and BirAER expression plasmids. This work would not have been possible without support from the Biological Services teams at both the Laboratory of Molecular Biology and Ares facilities. We are also very grateful to Nick Barry and Jerome Boulanger of the LMB Light Microscopy facility for support with confocal and STORM imaging and analysis, Junichi Takagi for providing scFv-Clasp expression constructs, Veronica Chang for assistance with scFv-Clasp protein production, and Nejc Kejzar for assistance with cluster analysis. We would like to thank Teru Nakagawa and Ole Paulsen for critical reading of the manuscript and constructive feedback. This work was supported by grants from the Medical Research Council (MC_U105174197) and BBSRC (BB/N002113/1).","department":[{"_id":"PeJo"}],"publication_status":"published","date_updated":"2023-08-11T11:07:51Z","article_type":"original","tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"file":[{"file_id":"9991","checksum":"1bf4f6a561f96bc426d754de9cb57710","relation":"main_file","date_updated":"2021-09-08T12:57:06Z","success":1,"content_type":"application/pdf","file_name":"2021_NatureCommunications_Watson.pdf","file_size":18310502,"creator":"cchlebak","date_created":"2021-09-08T12:57:06Z","access_level":"open_access"}],"intvolume":"        12","quality_controlled":"1","language":[{"iso":"eng"}],"oa_version":"Published Version","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","date_created":"2021-09-05T22:01:23Z","date_published":"2021-08-23T00:00:00Z","type":"journal_article","has_accepted_license":"1","isi":1,"article_number":"5083","author":[{"last_name":"Watson","orcid":"0000-0002-8698-3823","first_name":"Jake","id":"63836096-4690-11EA-BD4E-32803DDC885E","full_name":"Watson, Jake"},{"last_name":"Pinggera","full_name":"Pinggera, Alexandra","first_name":"Alexandra"},{"full_name":"Ho, Hinze","first_name":"Hinze","last_name":"Ho"},{"full_name":"Greger, Ingo H.","first_name":"Ingo H.","last_name":"Greger"}],"pmid":1,"abstract":[{"lang":"eng","text":"AMPA receptor (AMPAR) abundance and positioning at excitatory synapses regulates the strength of transmission. Changes in AMPAR localisation can enact synaptic plasticity, allowing long-term information storage, and is therefore tightly controlled. Multiple mechanisms regulating AMPAR synaptic anchoring have been described, but with limited coherence or comparison between reports, our understanding of this process is unclear. Here, combining synaptic recordings from mouse hippocampal slices and super-resolution imaging in dissociated cultures, we compare the contributions of three AMPAR interaction domains controlling transmission at hippocampal CA1 synapses. We show that the AMPAR C-termini play only a modulatory role, whereas the extracellular N-terminal domain (NTD) and PDZ interactions of the auxiliary subunit TARP γ8 are both crucial, and each is sufficient to maintain transmission. Our data support a model in which γ8 accumulates AMPARs at the postsynaptic density, where the NTD further tunes their positioning. This interplay between cytosolic (TARP γ8) and synaptic cleft (NTD) interactions provides versatility to regulate synaptic transmission and plasticity."}],"day":"23","publication_identifier":{"eissn":["2041-1723"]},"file_date_updated":"2021-09-08T12:57:06Z","doi":"10.1038/s41467-021-25281-4","publisher":"Nature Publishing Group","ddc":["612"],"fulldoi":"https://doi.org/10.1038/s41467-021-25281-4","scopus_import":"1","title":"AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP γ8 interactions","article_processing_charge":"Yes","oa":1,"status":"public","_id":"9985","month":"08","year":"2021","publication":"Nature Communications"},{"issue":"17","citation":{"mla":"Velasquez, Silvia Melina, et al. “Xyloglucan Remodeling Defines Auxin-Dependent Differential Tissue Expansion in Plants.” <i>International Journal of Molecular Sciences</i>, vol. 22, no. 17, 9222, MDPI, 2021, doi:<a href=\"https://doi.org/10.3390/ijms22179222\">10.3390/ijms22179222</a>.","apa":"Velasquez, S. M., Guo, X., Gallemi, M., Aryal, B., Venhuizen, P., Barbez, E., … Kleine-Vehn, J. (2021). Xyloglucan remodeling defines auxin-dependent differential tissue expansion in plants. <i>International Journal of Molecular Sciences</i>. MDPI. <a href=\"https://doi.org/10.3390/ijms22179222\">https://doi.org/10.3390/ijms22179222</a>","ama":"Velasquez SM, Guo X, Gallemi M, et al. Xyloglucan remodeling defines auxin-dependent differential tissue expansion in plants. <i>International Journal of Molecular Sciences</i>. 2021;22(17). doi:<a href=\"https://doi.org/10.3390/ijms22179222\">10.3390/ijms22179222</a>","ista":"Velasquez SM, Guo X, Gallemi M, Aryal B, Venhuizen P, Barbez E, Dünser KA, Darino M, Pӗnčík A, Novák O, Kalyna M, Mouille G, Benková E, Bhalerao RP, Mravec J, Kleine-Vehn J. 2021. Xyloglucan remodeling defines auxin-dependent differential tissue expansion in plants. International Journal of Molecular Sciences. 22(17), 9222.","short":"S.M. Velasquez, X. Guo, M. Gallemi, B. Aryal, P. Venhuizen, E. Barbez, K.A. Dünser, M. Darino, A. Pӗnčík, O. Novák, M. Kalyna, G. Mouille, E. Benková, R.P. Bhalerao, J. Mravec, J. Kleine-Vehn, International Journal of Molecular Sciences 22 (2021).","ieee":"S. M. Velasquez <i>et al.</i>, “Xyloglucan remodeling defines auxin-dependent differential tissue expansion in plants,” <i>International Journal of Molecular Sciences</i>, vol. 22, no. 17. MDPI, 2021.","chicago":"Velasquez, Silvia Melina, Xiaoyuan Guo, Marçal Gallemi, Bibek Aryal, Peter Venhuizen, Elke Barbez, Kai Alexander Dünser, et al. “Xyloglucan Remodeling Defines Auxin-Dependent Differential Tissue Expansion in Plants.” <i>International Journal of Molecular Sciences</i>. MDPI, 2021. <a href=\"https://doi.org/10.3390/ijms22179222\">https://doi.org/10.3390/ijms22179222</a>."},"external_id":{"isi":["000694347100001"],"pmid":["34502129"]},"acknowledgement":"We are grateful to Paul Knox, Markus Pauly, Malcom O’Neill, and Ignacio Zarra for providing published material; the BOKU-VIBT Imaging Center for access and M. Debreczeny for expertise; J.I. Thaker and Georg Seifert for critical reading.\r\n","volume":22,"publication_status":"published","department":[{"_id":"EvBe"}],"date_updated":"2024-10-09T21:00:50Z","article_type":"original","tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"file":[{"access_level":"open_access","date_created":"2021-09-06T12:50:19Z","file_size":2162247,"creator":"cchlebak","content_type":"application/pdf","file_name":"2021_IntJMolecularSciences_Velasquez.pdf","date_updated":"2021-09-07T09:04:53Z","file_id":"9988","relation":"main_file","checksum":"6b7055cf89f1b7ed8594c3fdf56f000b"}],"intvolume":"        22","quality_controlled":"1","language":[{"iso":"eng"}],"date_created":"2021-09-05T22:01:24Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","date_published":"2021-08-26T00:00:00Z","type":"journal_article","has_accepted_license":"1","isi":1,"corr_author":"1","article_number":"9222","keyword":["auxin","growth","cell wall","xyloglucans","hypocotyls","gravitropism"],"author":[{"full_name":"Velasquez, Silvia Melina","first_name":"Silvia Melina","last_name":"Velasquez"},{"last_name":"Guo","full_name":"Guo, Xiaoyuan","first_name":"Xiaoyuan"},{"last_name":"Gallemi","id":"460C6802-F248-11E8-B48F-1D18A9856A87","full_name":"Gallemi, Marçal","orcid":"0000-0003-4675-6893","first_name":"Marçal"},{"first_name":"Bibek","full_name":"Aryal, Bibek","last_name":"Aryal"},{"full_name":"Venhuizen, Peter","first_name":"Peter","last_name":"Venhuizen"},{"last_name":"Barbez","full_name":"Barbez, Elke","first_name":"Elke"},{"full_name":"Dünser, Kai Alexander","first_name":"Kai Alexander","last_name":"Dünser"},{"first_name":"Martin","full_name":"Darino, Martin","last_name":"Darino"},{"last_name":"Pӗnčík","full_name":"Pӗnčík, Aleš","first_name":"Aleš"},{"full_name":"Novák, Ondřej","first_name":"Ondřej","last_name":"Novák"},{"last_name":"Kalyna","full_name":"Kalyna, Maria","first_name":"Maria"},{"first_name":"Gregory","full_name":"Mouille, Gregory","last_name":"Mouille"},{"full_name":"Benková, Eva","id":"38F4F166-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8510-9739","first_name":"Eva","last_name":"Benková"},{"full_name":"Bhalerao, Rishikesh P.","first_name":"Rishikesh P.","last_name":"Bhalerao"},{"last_name":"Mravec","full_name":"Mravec, Jozef","first_name":"Jozef"},{"first_name":"Jürgen","full_name":"Kleine-Vehn, Jürgen","last_name":"Kleine-Vehn"}],"pmid":1,"abstract":[{"text":"Size control is a fundamental question in biology, showing incremental complexity in plants, whose cells possess a rigid cell wall. The phytohormone auxin is a vital growth regulator with central importance for differential growth control. Our results indicate that auxin-reliant growth programs affect the molecular complexity of xyloglucans, the major type of cell wall hemicellulose in eudicots. Auxin-dependent induction and repression of growth coincide with reduced and enhanced molecular complexity of xyloglucans, respectively. In agreement with a proposed function in growth control, genetic interference with xyloglucan side decorations distinctly modulates auxin-dependent differential growth rates. Our work proposes that auxin-dependent growth programs have a spatially defined effect on xyloglucan’s molecular structure, which in turn affects cell wall mechanics and specifies differential, gravitropic hypocotyl growth.","lang":"eng"}],"day":"26","publication_identifier":{"issn":["1661-6596"],"eissn":["1422-0067"]},"doi":"10.3390/ijms22179222","file_date_updated":"2021-09-07T09:04:53Z","publisher":"MDPI","fulldoi":"https://doi.org/10.3390/ijms22179222","ddc":["575"],"scopus_import":"1","title":"Xyloglucan remodeling defines auxin-dependent differential tissue expansion in plants","article_processing_charge":"Yes","oa":1,"month":"08","_id":"9986","status":"public","year":"2021","publication":"International Journal of Molecular Sciences"},{"oa":1,"article_processing_charge":"Yes","title":"Stateless model checking under a reads-value-from equivalence","scopus_import":"1","conference":{"end_date":"2021-07-23","name":"CAV: Computer Aided Verification ","location":"Virtual","start_date":"2021-07-20"},"alternative_title":["LNCS"],"publication":"33rd International Conference on Computer-Aided Verification ","year":"2021","_id":"9987","month":"07","status":"public","publication_identifier":{"eissn":["1611-3349"],"issn":["0302-9743"],"eisbn":["978-3-030-81685-8"],"isbn":["978-3-030-81684-1"]},"day":"15","ddc":["000"],"fulldoi":"https://doi.org/10.1007/978-3-030-81685-8_16","publisher":"Springer Nature","file_date_updated":"2022-05-13T07:00:20Z","doi":"10.1007/978-3-030-81685-8_16","author":[{"full_name":"Agarwal, Pratyush","first_name":"Pratyush","last_name":"Agarwal"},{"last_name":"Chatterjee","id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","full_name":"Chatterjee, Krishnendu","first_name":"Krishnendu","orcid":"0000-0002-4561-241X"},{"last_name":"Pathak","full_name":"Pathak, Shreya","first_name":"Shreya"},{"last_name":"Pavlogiannis","full_name":"Pavlogiannis, Andreas","id":"49704004-F248-11E8-B48F-1D18A9856A87","first_name":"Andreas","orcid":"0000-0002-8943-0722"},{"last_name":"Toman","orcid":"0000-0001-9036-063X","first_name":"Viktor","id":"3AF3DA7C-F248-11E8-B48F-1D18A9856A87","full_name":"Toman, Viktor"}],"abstract":[{"lang":"eng","text":"Stateless model checking (SMC) is one of the standard approaches to the verification of concurrent programs. As scheduling non-determinism creates exponentially large spaces of thread interleavings, SMC attempts to partition this space into equivalence classes and explore only a few representatives from each class. The efficiency of this approach depends on two factors: (a) the coarseness of the partitioning, and (b) the time to generate representatives in each class. For this reason, the search for coarse partitionings that are efficiently explorable is an active research challenge. In this work we present   RVF-SMC , a new SMC algorithm that uses a novel reads-value-from (RVF) partitioning. Intuitively, two interleavings are deemed equivalent if they agree on the value obtained in each read event, and read events induce consistent causal orderings between them. The RVF partitioning is provably coarser than recent approaches based on Mazurkiewicz and “reads-from” partitionings. Our experimental evaluation reveals that RVF is quite often a very effective equivalence, as the underlying partitioning is exponentially coarser than other approaches. Moreover,   RVF-SMC  generates representatives very efficiently, as the reduction in the partitioning is often met with significant speed-ups in the model checking task."}],"related_material":{"record":[{"relation":"dissertation_contains","id":"10199","status":"public"}]},"isi":1,"corr_author":"1","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","date_created":"2021-09-05T22:01:24Z","oa_version":"Published Version","language":[{"iso":"eng"}],"quality_controlled":"1","arxiv":1,"has_accepted_license":"1","type":"conference","date_published":"2021-07-15T00:00:00Z","date_updated":"2026-04-08T07:00:30Z","department":[{"_id":"KrCh"}],"publication_status":"published","file":[{"access_level":"open_access","date_created":"2022-05-13T07:00:20Z","creator":"dernst","file_size":1516756,"file_name":"2021_LNCS_Agarwal.pdf","content_type":"application/pdf","success":1,"date_updated":"2022-05-13T07:00:20Z","relation":"main_file","checksum":"4b346e5fbaa8b9bdf107819c7b2aadee","file_id":"11368"}],"tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"volume":"12759 ","acknowledgement":"The research was partially funded by the ERC CoG 863818 (ForM-SMArt) and the Vienna Science and Technology Fund (WWTF) through project ICT15-003.","project":[{"name":"Efficient Algorithms for Computer Aided Verification","grant_number":"ICT15-003","_id":"25892FC0-B435-11E9-9278-68D0E5697425"},{"call_identifier":"H2020","grant_number":"863818","name":"Formal Methods for Stochastic Models: Algorithms and Applications","_id":"0599E47C-7A3F-11EA-A408-12923DDC885E"}],"ec_funded":1,"external_id":{"isi":["000698732400016"],"arxiv":["2105.06424"]},"page":"341-366","citation":{"apa":"Agarwal, P., Chatterjee, K., Pathak, S., Pavlogiannis, A., &#38; Toman, V. (2021). Stateless model checking under a reads-value-from equivalence. In <i>33rd International Conference on Computer-Aided Verification </i> (Vol. 12759, pp. 341–366). Virtual: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-030-81685-8_16\">https://doi.org/10.1007/978-3-030-81685-8_16</a>","mla":"Agarwal, Pratyush, et al. “Stateless Model Checking under a Reads-Value-from Equivalence.” <i>33rd International Conference on Computer-Aided Verification </i>, vol. 12759, Springer Nature, 2021, pp. 341–66, doi:<a href=\"https://doi.org/10.1007/978-3-030-81685-8_16\">10.1007/978-3-030-81685-8_16</a>.","ama":"Agarwal P, Chatterjee K, Pathak S, Pavlogiannis A, Toman V. Stateless model checking under a reads-value-from equivalence. In: <i>33rd International Conference on Computer-Aided Verification </i>. Vol 12759. Springer Nature; 2021:341-366. doi:<a href=\"https://doi.org/10.1007/978-3-030-81685-8_16\">10.1007/978-3-030-81685-8_16</a>","ista":"Agarwal P, Chatterjee K, Pathak S, Pavlogiannis A, Toman V. 2021. Stateless model checking under a reads-value-from equivalence. 33rd International Conference on Computer-Aided Verification . CAV: Computer Aided Verification , LNCS, vol. 12759, 341–366.","short":"P. Agarwal, K. Chatterjee, S. Pathak, A. Pavlogiannis, V. Toman, in:, 33rd International Conference on Computer-Aided Verification , Springer Nature, 2021, pp. 341–366.","ieee":"P. Agarwal, K. Chatterjee, S. Pathak, A. Pavlogiannis, and V. Toman, “Stateless model checking under a reads-value-from equivalence,” in <i>33rd International Conference on Computer-Aided Verification </i>, Virtual, 2021, vol. 12759, pp. 341–366.","chicago":"Agarwal, Pratyush, Krishnendu Chatterjee, Shreya Pathak, Andreas Pavlogiannis, and Viktor Toman. “Stateless Model Checking under a Reads-Value-from Equivalence.” In <i>33rd International Conference on Computer-Aided Verification </i>, 12759:341–66. Springer Nature, 2021. <a href=\"https://doi.org/10.1007/978-3-030-81685-8_16\">https://doi.org/10.1007/978-3-030-81685-8_16</a>."}},{"day":"30","publication_identifier":{"eissn":["1420-9020"],"issn":["1022-1824"]},"doi":"10.1007/s00029-021-00698-3","file_date_updated":"2021-09-13T11:31:34Z","publisher":"Springer Nature","ddc":["530"],"fulldoi":"https://doi.org/10.1007/s00029-021-00698-3","scopus_import":"1","title":"Quantum K-theory of quiver varieties and many-body systems","article_processing_charge":"Yes (via OA deal)","oa":1,"month":"08","_id":"9998","status":"public","year":"2021","publication":"Selecta Mathematica","isi":1,"article_number":"87","author":[{"first_name":"Peter","full_name":"Koroteev, Peter","last_name":"Koroteev"},{"last_name":"Pushkar","first_name":"Petr","full_name":"Pushkar, Petr","id":"151DCEB6-9EC3-11E9-8480-ABECE5697425"},{"first_name":"Andrey V.","full_name":"Smirnov, Andrey V.","last_name":"Smirnov"},{"full_name":"Zeitlin, Anton M.","first_name":"Anton M.","last_name":"Zeitlin"}],"abstract":[{"lang":"eng","text":"We define quantum equivariant K-theory of Nakajima quiver varieties. We discuss type A in detail as well as its connections with quantum XXZ spin chains and trigonometric Ruijsenaars-Schneider models. Finally we study a limit which produces a K-theoretic version of results of Givental and Kim, connecting quantum geometry of flag varieties and Toda lattice."}],"department":[{"_id":"TaHa"}],"publication_status":"published","date_updated":"2025-04-15T06:53:09Z","article_type":"original","tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"file":[{"date_updated":"2021-09-13T11:31:34Z","relation":"main_file","checksum":"beadc5a722ffb48190e1e63ee2dbfee5","file_id":"10010","file_name":"2021_SelectaMath_Koroteev.pdf","content_type":"application/pdf","success":1,"date_created":"2021-09-13T11:31:34Z","creator":"cchlebak","file_size":584648,"access_level":"open_access"}],"intvolume":"        27","quality_controlled":"1","language":[{"iso":"eng"}],"oa_version":"Published Version","date_created":"2021-09-12T22:01:22Z","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","date_published":"2021-08-30T00:00:00Z","type":"journal_article","has_accepted_license":"1","issue":"5","citation":{"chicago":"Koroteev, Peter, Petr Pushkar, Andrey V. Smirnov, and Anton M. Zeitlin. “Quantum K-Theory of Quiver Varieties and Many-Body Systems.” <i>Selecta Mathematica</i>. Springer Nature, 2021. <a href=\"https://doi.org/10.1007/s00029-021-00698-3\">https://doi.org/10.1007/s00029-021-00698-3</a>.","ista":"Koroteev P, Pushkar P, Smirnov AV, Zeitlin AM. 2021. Quantum K-theory of quiver varieties and many-body systems. Selecta Mathematica. 27(5), 87.","ama":"Koroteev P, Pushkar P, Smirnov AV, Zeitlin AM. Quantum K-theory of quiver varieties and many-body systems. <i>Selecta Mathematica</i>. 2021;27(5). doi:<a href=\"https://doi.org/10.1007/s00029-021-00698-3\">10.1007/s00029-021-00698-3</a>","apa":"Koroteev, P., Pushkar, P., Smirnov, A. V., &#38; Zeitlin, A. M. (2021). Quantum K-theory of quiver varieties and many-body systems. <i>Selecta Mathematica</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00029-021-00698-3\">https://doi.org/10.1007/s00029-021-00698-3</a>","mla":"Koroteev, Peter, et al. “Quantum K-Theory of Quiver Varieties and Many-Body Systems.” <i>Selecta Mathematica</i>, vol. 27, no. 5, 87, Springer Nature, 2021, doi:<a href=\"https://doi.org/10.1007/s00029-021-00698-3\">10.1007/s00029-021-00698-3</a>.","ieee":"P. Koroteev, P. Pushkar, A. V. Smirnov, and A. M. Zeitlin, “Quantum K-theory of quiver varieties and many-body systems,” <i>Selecta Mathematica</i>, vol. 27, no. 5. Springer Nature, 2021.","short":"P. Koroteev, P. Pushkar, A.V. Smirnov, A.M. Zeitlin, Selecta Mathematica 27 (2021)."},"external_id":{"isi":["000692795200001"]},"project":[{"_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854","name":"IST Austria Open Access Fund"}],"volume":27,"acknowledgement":"First of all we would like to thank Andrei Okounkov for invaluable discussions, advises and sharing with us his fantastic viewpoint on modern quantum geometry. We are also grateful to D. Korb and Z. Zhou for their interest and comments. The work of A. Smirnov was supported in part by RFBR Grants under Numbers 15-02-04175 and 15-01-04217 and in part by NSF Grant DMS–2054527. The work of P. Koroteev, A.M. Zeitlin and A. Smirnov is supported in part by AMS Simons travel Grant. A. M. Zeitlin is partially supported by Simons Collaboration Grant, Award ID: 578501. Open access funding provided by Institute of Science and Technology (IST Austria)."},{"has_accepted_license":"1","type":"journal_article","date_published":"2021-08-27T00:00:00Z","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","date_created":"2021-09-12T22:01:23Z","oa_version":"Published Version","language":[{"iso":"eng"}],"intvolume":"        10","quality_controlled":"1","file":[{"date_created":"2022-05-13T08:03:37Z","creator":"dernst","file_size":9010446,"access_level":"open_access","date_updated":"2022-05-13T08:03:37Z","checksum":"a3f82b0499cc822ac1eab48a01f3f57e","relation":"main_file","file_id":"11371","file_name":"2021_eLife_Pulgar.pdf","content_type":"application/pdf","success":1}],"tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"article_type":"original","date_updated":"2025-04-14T07:46:58Z","publication_status":"published","department":[{"_id":"CaHe"}],"volume":10,"project":[{"call_identifier":"H2020","grant_number":"742573","name":"Interaction and feedback between cell mechanics and fate specification in vertebrate gastrulation","_id":"260F1432-B435-11E9-9278-68D0E5697425"}],"external_id":{"pmid":["34448451"],"isi":["000700428500001"]},"citation":{"chicago":"Pulgar, Eduardo, Cornelia Schwayer, Néstor Guerrero, Loreto López, Susana Márquez, Steffen Härtel, Rodrigo Soto, Carl Philipp Heisenberg, and Miguel L. Concha. “Apical Contacts Stemming from Incomplete Delamination Guide Progenitor Cell Allocation through a Dragging Mechanism.” <i>ELife</i>. eLife Sciences Publications, 2021. <a href=\"https://doi.org/10.7554/eLife.66483\">https://doi.org/10.7554/eLife.66483</a>.","ama":"Pulgar E, Schwayer C, Guerrero N, et al. Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism. <i>eLife</i>. 2021;10. doi:<a href=\"https://doi.org/10.7554/eLife.66483\">10.7554/eLife.66483</a>","ista":"Pulgar E, Schwayer C, Guerrero N, López L, Márquez S, Härtel S, Soto R, Heisenberg CP, Concha ML. 2021. Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism. eLife. 10, e66483.","mla":"Pulgar, Eduardo, et al. “Apical Contacts Stemming from Incomplete Delamination Guide Progenitor Cell Allocation through a Dragging Mechanism.” <i>ELife</i>, vol. 10, e66483, eLife Sciences Publications, 2021, doi:<a href=\"https://doi.org/10.7554/eLife.66483\">10.7554/eLife.66483</a>.","apa":"Pulgar, E., Schwayer, C., Guerrero, N., López, L., Márquez, S., Härtel, S., … Concha, M. L. (2021). Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism. <i>ELife</i>. eLife Sciences Publications. <a href=\"https://doi.org/10.7554/eLife.66483\">https://doi.org/10.7554/eLife.66483</a>","ieee":"E. Pulgar <i>et al.</i>, “Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism,” <i>eLife</i>, vol. 10. eLife Sciences Publications, 2021.","short":"E. Pulgar, C. Schwayer, N. Guerrero, L. López, S. Márquez, S. Härtel, R. Soto, C.P. Heisenberg, M.L. Concha, ELife 10 (2021)."},"ec_funded":1,"publication":"eLife","year":"2021","_id":"9999","month":"08","status":"public","oa":1,"article_processing_charge":"Yes","title":"Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism","scopus_import":"1","fulldoi":"https://doi.org/10.7554/eLife.66483","ddc":["570"],"publisher":"eLife Sciences Publications","file_date_updated":"2022-05-13T08:03:37Z","doi":"10.7554/eLife.66483","publication_identifier":{"eissn":["2050-084X"]},"day":"27","abstract":[{"lang":"eng","text":"The developmental strategies used by progenitor cells to endure a safe journey from their induction place towards the site of terminal differentiation are still poorly understood. Here we uncovered a progenitor cell allocation mechanism that stems from an incomplete process of epithelial delamination that allows progenitors to coordinate their movement with adjacent extra-embryonic tissues. Progenitors of the zebrafish laterality organ originate from the surface epithelial enveloping layer by an apical constriction process of cell delamination. During this process, progenitors retain long-term apical contacts that enable the epithelial layer to pull a subset of progenitors along their way towards the vegetal pole. The remaining delaminated progenitors follow apically-attached progenitors’ movement by a co-attraction mechanism, avoiding sequestration by the adjacent endoderm, ensuring their fate and collective allocation at the differentiation site. Thus, we reveal that incomplete delamination serves as a cellular platform for coordinated tissue movements during development. Impact Statement: Incomplete delamination serves as a cellular platform for coordinated tissue movements during development, guiding newly formed progenitor cell groups to the differentiation site."}],"pmid":1,"author":[{"last_name":"Pulgar","first_name":"Eduardo","full_name":"Pulgar, Eduardo"},{"orcid":"0000-0001-5130-2226","first_name":"Cornelia","id":"3436488C-F248-11E8-B48F-1D18A9856A87","full_name":"Schwayer, Cornelia","last_name":"Schwayer"},{"last_name":"Guerrero","first_name":"Néstor","full_name":"Guerrero, Néstor"},{"last_name":"López","full_name":"López, Loreto","first_name":"Loreto"},{"last_name":"Márquez","first_name":"Susana","full_name":"Márquez, Susana"},{"last_name":"Härtel","first_name":"Steffen","full_name":"Härtel, Steffen"},{"last_name":"Soto","full_name":"Soto, Rodrigo","first_name":"Rodrigo"},{"full_name":"Heisenberg, Carl Philipp","first_name":"Carl Philipp","last_name":"Heisenberg"},{"first_name":"Miguel L.","full_name":"Concha, Miguel L.","last_name":"Concha"}],"keyword":["cell delamination","apical constriction","dragging","mechanical forces","collective 18 locomotion","dorsal forerunner cells","zebrafish"],"article_number":"e66483","isi":1},{"type":"journal_article","date_published":"2021-10-19T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2021-11-21T23:01:30Z","oa_version":"Submitted Version","language":[{"iso":"eng"}],"intvolume":"        13","quality_controlled":"1","article_type":"original","date_updated":"2026-07-06T12:15:05Z","department":[{"_id":"MaIb"}],"publication_status":"published","acknowledgement":"This work was supported by the European Regional Development Funds. M.L., Y.Z., X.H., and K.X. thank the China Scholarship Council for scholarship support. M. I. has been financially supported by IST Austria and the Werner Siemens Foundation. Y.L. acknowledges funding from the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant agreement No. 754411. J.L. is a Serra Húnter fellow and is grateful to ICREA Academia program and projects MICINN/FEDER RTI2018-093996-B-C31 and GC 2017 SGR 128. ICN2 acknowledges funding from Generalitat de Catalunya 2017 SGR 327 and the Spanish MINECO project NANOGEN (PID2020-116093RB-C43). ICN2 was supported by the Severo Ochoa program from Spanish MINECO (grant no. SEV-2017-0706) and was funded by the CERCA Programme/Generalitat de Catalunya. X.H. thanks China Scholarship Council for scholarship support (201804910551). Part of the present work was performed in the framework of Universitat Autònoma de Barcelona Materials Science Ph.D. program.","volume":13,"project":[{"grant_number":"754411","name":"ISTplus - Postdoctoral Fellowships","_id":"260C2330-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"},{"_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A","name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery"}],"external_id":{"pmid":["34665616"],"isi":["000715852100070"]},"citation":{"ista":"Li M, Liu Y, Zhang Y, Han X, Xiao K, Nabahat M, Arbiol J, Llorca J, Ibáñez M, Cabot A. 2021. PbS–Pb–CuxS composites for thermoelectric application. ACS Applied Materials and Interfaces. 13(43), 51373–51382.","ama":"Li M, Liu Y, Zhang Y, et al. PbS–Pb–CuxS composites for thermoelectric application. <i>ACS Applied Materials and Interfaces</i>. 2021;13(43):51373–51382. doi:<a href=\"https://doi.org/10.1021/acsami.1c15609\">10.1021/acsami.1c15609</a>","mla":"Li, Mengyao, et al. “PbS–Pb–CuxS Composites for Thermoelectric Application.” <i>ACS Applied Materials and Interfaces</i>, vol. 13, no. 43, American Chemical Society, 2021, pp. 51373–51382, doi:<a href=\"https://doi.org/10.1021/acsami.1c15609\">10.1021/acsami.1c15609</a>.","apa":"Li, M., Liu, Y., Zhang, Y., Han, X., Xiao, K., Nabahat, M., … Cabot, A. (2021). PbS–Pb–CuxS composites for thermoelectric application. <i>ACS Applied Materials and Interfaces</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsami.1c15609\">https://doi.org/10.1021/acsami.1c15609</a>","ieee":"M. Li <i>et al.</i>, “PbS–Pb–CuxS composites for thermoelectric application,” <i>ACS Applied Materials and Interfaces</i>, vol. 13, no. 43. American Chemical Society, pp. 51373–51382, 2021.","short":"M. Li, Y. Liu, Y. Zhang, X. Han, K. Xiao, M. Nabahat, J. Arbiol, J. Llorca, M. Ibáñez, A. Cabot, ACS Applied Materials and Interfaces 13 (2021) 51373–51382.","chicago":"Li, Mengyao, Yu Liu, Yu Zhang, Xu Han, Ke Xiao, Mehran Nabahat, Jordi Arbiol, Jordi Llorca, Maria Ibáñez, and Andreu Cabot. “PbS–Pb–CuxS Composites for Thermoelectric Application.” <i>ACS Applied Materials and Interfaces</i>. American Chemical Society, 2021. <a href=\"https://doi.org/10.1021/acsami.1c15609\">https://doi.org/10.1021/acsami.1c15609</a>."},"page":"51373–51382","main_file_link":[{"open_access":"1","url":"https://upcommons.upc.edu/bitstream/2117/363528/1/Pb%20mengyao.pdf"}],"issue":"43","ec_funded":1,"publication":"ACS Applied Materials and Interfaces","year":"2021","_id":"10327","status":"public","month":"10","oa":1,"article_processing_charge":"No","title":"PbS–Pb–CuxS composites for thermoelectric application","scopus_import":"1","fulldoi":"https://doi.org/10.1021/acsami.1c15609","publisher":"American Chemical Society","doi":"10.1021/acsami.1c15609","publication_identifier":{"issn":["1944-8244"],"eissn":["1944-8252"]},"day":"19","abstract":[{"lang":"eng","text":"Composite materials offer numerous advantages in a wide range of applications, including thermoelectrics. Here, semiconductor–metal composites are produced by just blending nanoparticles of a sulfide semiconductor obtained in aqueous solution and at room temperature with a metallic Cu powder. The obtained blend is annealed in a reducing atmosphere and afterward consolidated into dense polycrystalline pellets through spark plasma sintering (SPS). We observe that, during the annealing process, the presence of metallic copper activates a partial reduction of the PbS, resulting in the formation of PbS–Pb–CuxS composites. The presence of metallic lead during the SPS process habilitates the liquid-phase sintering of the composite. Besides, by comparing the transport properties of PbS, the PbS–Pb–CuxS composites, and PbS–CuxS composites obtained by blending PbS and CuxS nanoparticles, we demonstrate that the presence of metallic lead decisively contributes to a strong increase of the charge carrier concentration through spillover of charge carriers enabled by the low work function of lead. The increase in charge carrier concentration translates into much higher electrical conductivities and moderately lower Seebeck coefficients. These properties translate into power factors up to 2.1 mW m–1 K–2 at ambient temperature, well above those of PbS and PbS + CuxS. Additionally, the presence of multiple phases in the final composite results in a notable decrease in the lattice thermal conductivity. Overall, the introduction of metallic copper in the initial blend results in a significant improvement of the thermoelectric performance of PbS, reaching a dimensionless thermoelectric figure of merit ZT = 1.1 at 750 K, which represents about a 400% increase over bare PbS. Besides, an average ZTave = 0.72 in the temperature range 320–773 K is demonstrated."}],"pmid":1,"author":[{"full_name":"Li, Mengyao","first_name":"Mengyao","last_name":"Li"},{"full_name":"Liu, Yu","id":"2A70014E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-7313-6740","first_name":"Yu","last_name":"Liu"},{"last_name":"Zhang","full_name":"Zhang, Yu","first_name":"Yu"},{"full_name":"Han, Xu","first_name":"Xu","last_name":"Han"},{"full_name":"Xiao, Ke","first_name":"Ke","last_name":"Xiao"},{"last_name":"Nabahat","first_name":"Mehran","full_name":"Nabahat, Mehran"},{"last_name":"Arbiol","full_name":"Arbiol, Jordi","first_name":"Jordi"},{"last_name":"Llorca","first_name":"Jordi","full_name":"Llorca, Jordi"},{"orcid":"0000-0001-5013-2843","first_name":"Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87","full_name":"Ibáñez, Maria","last_name":"Ibáñez"},{"last_name":"Cabot","first_name":"Andreu","full_name":"Cabot, Andreu"}],"keyword":["CuxS","PbS","energy conversion","nanocomposite","nanoparticle","solution synthesis","thermoelectric"],"isi":1,"das_tickbox":"1","corr_author":"1"},{"keyword":["General Engineering","General Physics and Astronomy","General Materials Science"],"das_tickbox":"1","corr_author":"1","isi":1,"pmid":1,"author":[{"last_name":"Li","full_name":"Li, Mengyao","first_name":"Mengyao"},{"last_name":"Liu","id":"2A70014E-F248-11E8-B48F-1D18A9856A87","full_name":"Liu, Yu","orcid":"0000-0001-7313-6740","first_name":"Yu"},{"full_name":"Zhang, Yu","first_name":"Yu","last_name":"Zhang"},{"last_name":"Han","first_name":"Xu","full_name":"Han, Xu"},{"last_name":"Zhang","first_name":"Ting","full_name":"Zhang, Ting"},{"first_name":"Yong","full_name":"Zuo, Yong","last_name":"Zuo"},{"full_name":"Xie, Chenyang","first_name":"Chenyang","last_name":"Xie"},{"last_name":"Xiao","first_name":"Ke","full_name":"Xiao, Ke"},{"first_name":"Jordi","full_name":"Arbiol, Jordi","last_name":"Arbiol"},{"last_name":"Llorca","full_name":"Llorca, Jordi","first_name":"Jordi"},{"full_name":"Ibáñez, Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5013-2843","first_name":"Maria","last_name":"Ibáñez"},{"full_name":"Liu, Junfeng","first_name":"Junfeng","last_name":"Liu"},{"last_name":"Cabot","full_name":"Cabot, Andreu","first_name":"Andreu"}],"abstract":[{"lang":"eng","text":"Cu2–xS has become one of the most promising thermoelectric materials for application in the middle-high temperature range. Its advantages include the abundance, low cost, and safety of its elements and a high performance at relatively elevated temperatures. However, stability issues limit its operation current and temperature, thus calling for the optimization of the material performance in the middle temperature range. Here, we present a synthetic protocol for large scale production of covellite CuS nanoparticles at ambient temperature and atmosphere, and using water as a solvent. The crystal phase and stoichiometry of the particles are afterward tuned through an annealing process at a moderate temperature under inert or reducing atmosphere. While annealing under argon results in Cu1.8S nanopowder with a rhombohedral crystal phase, annealing in an atmosphere containing hydrogen leads to tetragonal Cu1.96S. High temperature X-ray diffraction analysis shows the material annealed in argon to transform to the cubic phase at ca. 400 K, while the material annealed in the presence of hydrogen undergoes two phase transitions, first to hexagonal and then to the cubic structure. The annealing atmosphere, temperature, and time allow adjustment of the density of copper vacancies and thus tuning of the charge carrier concentration and material transport properties. In this direction, the material annealed under Ar is characterized by higher electrical conductivities but lower Seebeck coefficients than the material annealed in the presence of hydrogen. By optimizing the charge carrier concentration through the annealing time, Cu2–xS with record figures of merit in the middle temperature range, up to 1.41 at 710 K, is obtained. We finally demonstrate that this strategy, based on a low-cost and scalable solution synthesis process, is also suitable for the production of high performance Cu2–xS layers using high throughput and cost-effective printing technologies."}],"publication_identifier":{"issn":["1936-0851"],"eissn":["1936-086X"]},"day":"01","fulldoi":"https://doi.org/10.1021/acsnano.0c09866","publisher":"American Chemical Society","doi":"10.1021/acsnano.0c09866","oa":1,"article_processing_charge":"No","title":"Effect of the annealing atmosphere on crystal phase and thermoelectric properties of copper sulfide","scopus_import":"1","publication":"ACS Nano","year":"2021","status":"public","_id":"9235","month":"03","issue":"3","external_id":{"isi":["000634569100106"],"pmid":["33645986"]},"page":"4967–4978","citation":{"chicago":"Li, Mengyao, Yu Liu, Yu Zhang, Xu Han, Ting Zhang, Yong Zuo, Chenyang Xie, et al. “Effect of the Annealing Atmosphere on Crystal Phase and Thermoelectric Properties of Copper Sulfide.” <i>ACS Nano</i>. American Chemical Society, 2021. <a href=\"https://doi.org/10.1021/acsnano.0c09866\">https://doi.org/10.1021/acsnano.0c09866</a>.","ieee":"M. Li <i>et al.</i>, “Effect of the annealing atmosphere on crystal phase and thermoelectric properties of copper sulfide,” <i>ACS Nano</i>, vol. 15, no. 3. American Chemical Society, pp. 4967–4978, 2021.","short":"M. Li, Y. Liu, Y. Zhang, X. Han, T. Zhang, Y. Zuo, C. Xie, K. Xiao, J. Arbiol, J. Llorca, M. Ibáñez, J. Liu, A. Cabot, ACS Nano 15 (2021) 4967–4978.","ista":"Li M, Liu Y, Zhang Y, Han X, Zhang T, Zuo Y, Xie C, Xiao K, Arbiol J, Llorca J, Ibáñez M, Liu J, Cabot A. 2021. Effect of the annealing atmosphere on crystal phase and thermoelectric properties of copper sulfide. ACS Nano. 15(3), 4967–4978.","ama":"Li M, Liu Y, Zhang Y, et al. Effect of the annealing atmosphere on crystal phase and thermoelectric properties of copper sulfide. <i>ACS Nano</i>. 2021;15(3):4967–4978. doi:<a href=\"https://doi.org/10.1021/acsnano.0c09866\">10.1021/acsnano.0c09866</a>","apa":"Li, M., Liu, Y., Zhang, Y., Han, X., Zhang, T., Zuo, Y., … Cabot, A. (2021). Effect of the annealing atmosphere on crystal phase and thermoelectric properties of copper sulfide. <i>ACS Nano</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsnano.0c09866\">https://doi.org/10.1021/acsnano.0c09866</a>","mla":"Li, Mengyao, et al. “Effect of the Annealing Atmosphere on Crystal Phase and Thermoelectric Properties of Copper Sulfide.” <i>ACS Nano</i>, vol. 15, no. 3, American Chemical Society, 2021, pp. 4967–4978, doi:<a href=\"https://doi.org/10.1021/acsnano.0c09866\">10.1021/acsnano.0c09866</a>."},"main_file_link":[{"open_access":"1","url":"https://upcommons.upc.edu/bitstream/handle/2117/363528/Pb%20mengyao.pdf?sequence=1&isAllowed=y"}],"acknowledgement":"This work was supported by the European Regional Development Funds. M.Y.L., X.H., T.Z., and K.X. thank the China Scholarship Council for scholarship support. M.I. acknowledges financial support from IST Austria. J.L. acknowledges support from the National Natural Science Foundation of China (No. 22008091), the funding for scientific research startup of Jiangsu University (No. 19JDG044), and Jiangsu Provincial Program for High-Level Innovative and Entrepreneurial Talents Introduction. J.L. is a Serra Húnter fellow and is grateful to the ICREA Academia program and projects MICINN/FEDER RTI2018-093996-B-C31 and GC 2017 SGR 128. ICN2 acknowledges funding from Generalitat de Catalunya 2017 SGR 327 and the Spanish MINECO ENE2017-85087-C3. ICN2 is supported by the Severo Ochoa program from Spanish MINECO (Grant No. SEV-2017-0706) and is funded by the CERCA Programme/Generalitat de Catalunya. Part of the present work has been performed in the framework of Universitat Autònoma de Barcelona Materials Science PhD program. T.Z. has received funding from the CSC-UAB PhD scholarship program.","volume":15,"date_updated":"2026-07-06T12:15:39Z","publication_status":"published","department":[{"_id":"MaIb"}],"article_type":"original","date_created":"2021-03-10T20:12:45Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Submitted Version","language":[{"iso":"eng"}],"intvolume":"        15","quality_controlled":"1","type":"journal_article","date_published":"2021-03-01T00:00:00Z"},{"type":"journal_article","date_published":"2021-10-12T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Preprint","date_created":"2021-10-13T09:21:33Z","language":[{"iso":"eng"}],"intvolume":"       127","arxiv":1,"quality_controlled":"1","article_type":"original","date_updated":"2026-07-06T12:22:26Z","publication_status":"published","department":[{"_id":"MiLe"}],"acknowledgement":"We acknowledge helpful discussions with W. G. Unruh and A. Rodriguez. F. S. is supported by European Union’s\r\nHorizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant No. 754411. M. L. acknowledges support by the European Research Council (ERC) Starting Grant No. 801770 (ANGULON). W. H. Z. is\r\nsupported by Department of Energy under the Los\r\nAlamos National Laboratory LDRD Program as well as by the U.S. Department of Energy, Office of Science, Basic\r\nEnergy Sciences, Materials Sciences and Engineering Division, Condensed Matter Theory Program. R. V. K. is supported by NSERC of Canada.\r\n","volume":127,"project":[{"_id":"260C2330-B435-11E9-9278-68D0E5697425","grant_number":"754411","name":"ISTplus - Postdoctoral Fellowships","call_identifier":"H2020"},{"name":"Angulon: physics and applications of a new quasiparticle","grant_number":"801770","_id":"2688CF98-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"}],"external_id":{"arxiv":["2011.06279"],"isi":["000707495700001"]},"citation":{"ista":"Suzuki F, Lemeshko M, Zurek WH, Krems RV. 2021. Anderson localization of composite particles. Physical Review Letters. 127(16), 160602.","ama":"Suzuki F, Lemeshko M, Zurek WH, Krems RV. Anderson localization of composite particles. <i>Physical Review Letters</i>. 2021;127(16). doi:<a href=\"https://doi.org/10.1103/physrevlett.127.160602\">10.1103/physrevlett.127.160602</a>","mla":"Suzuki, Fumika, et al. “Anderson Localization of Composite Particles.” <i>Physical Review Letters</i>, vol. 127, no. 16, 160602, American Physical Society, 2021, doi:<a href=\"https://doi.org/10.1103/physrevlett.127.160602\">10.1103/physrevlett.127.160602</a>.","apa":"Suzuki, F., Lemeshko, M., Zurek, W. H., &#38; Krems, R. V. (2021). Anderson localization of composite particles. <i>Physical Review Letters</i>. American Physical Society. <a href=\"https://doi.org/10.1103/physrevlett.127.160602\">https://doi.org/10.1103/physrevlett.127.160602</a>","ieee":"F. Suzuki, M. Lemeshko, W. H. Zurek, and R. V. Krems, “Anderson localization of composite particles,” <i>Physical Review Letters</i>, vol. 127, no. 16. American Physical Society, 2021.","short":"F. Suzuki, M. Lemeshko, W.H. Zurek, R.V. Krems, Physical Review Letters 127 (2021).","chicago":"Suzuki, Fumika, Mikhail Lemeshko, Wojciech H. Zurek, and Roman V. Krems. “Anderson Localization of Composite Particles.” <i>Physical Review Letters</i>. American Physical Society, 2021. <a href=\"https://doi.org/10.1103/physrevlett.127.160602\">https://doi.org/10.1103/physrevlett.127.160602</a>."},"main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/2011.06279"}],"issue":"16","ec_funded":1,"publication":"Physical Review Letters","year":"2021","_id":"10134","month":"10","status":"public","oa":1,"article_processing_charge":"No","title":"Anderson localization of composite particles","scopus_import":"1","fulldoi":"https://doi.org/10.1103/physrevlett.127.160602","publisher":"American Physical Society","doi":"10.1103/physrevlett.127.160602","publication_identifier":{"issn":["0031-9007"],"eissn":["1079-7114"]},"day":"12","abstract":[{"text":"We investigate the effect of coupling between translational and internal degrees of freedom of composite quantum particles on their localization in a random potential. We show that entanglement between the two degrees of freedom weakens localization due to the upper bound imposed on the inverse participation ratio by purity of a quantum state. We perform numerical calculations for a two-particle system bound by a harmonic force in a 1D disordered lattice and a rigid rotor in a 2D disordered lattice. We illustrate that the coupling has a dramatic effect on localization properties, even with a small number of internal states participating in quantum dynamics.","lang":"eng"}],"author":[{"id":"650C99FC-1079-11EA-A3C0-73AE3DDC885E","full_name":"Suzuki, Fumika","orcid":"0000-0003-4982-5970","first_name":"Fumika","last_name":"Suzuki"},{"last_name":"Lemeshko","orcid":"0000-0002-6990-7802","first_name":"Mikhail","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","full_name":"Lemeshko, Mikhail"},{"last_name":"Zurek","first_name":"Wojciech H.","full_name":"Zurek, Wojciech H."},{"last_name":"Krems","full_name":"Krems, Roman V.","first_name":"Roman V."}],"keyword":["General Physics and Astronomy"],"article_number":"160602","isi":1,"das_tickbox":"1","corr_author":"1"},{"citation":{"chicago":"Kavcic, Bor, Gašper Tkačik, and Mark Tobias Bollenbach. “Minimal Biophysical Model of Combined Antibiotic Action.” <i>PLOS Computational Biology</i>. Public Library of Science, 2021. <a href=\"https://doi.org/10.1371/journal.pcbi.1008529\">https://doi.org/10.1371/journal.pcbi.1008529</a>.","mla":"Kavcic, Bor, et al. “Minimal Biophysical Model of Combined Antibiotic Action.” <i>PLOS Computational Biology</i>, vol. 17, e1008529, Public Library of Science, 2021, doi:<a href=\"https://doi.org/10.1371/journal.pcbi.1008529\">10.1371/journal.pcbi.1008529</a>.","apa":"Kavcic, B., Tkačik, G., &#38; Bollenbach, M. T. (2021). Minimal biophysical model of combined antibiotic action. <i>PLOS Computational Biology</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pcbi.1008529\">https://doi.org/10.1371/journal.pcbi.1008529</a>","ista":"Kavcic B, Tkačik G, Bollenbach MT. 2021. Minimal biophysical model of combined antibiotic action. PLOS Computational Biology. 17, e1008529.","ama":"Kavcic B, Tkačik G, Bollenbach MT. Minimal biophysical model of combined antibiotic action. <i>PLOS Computational Biology</i>. 2021;17. doi:<a href=\"https://doi.org/10.1371/journal.pcbi.1008529\">10.1371/journal.pcbi.1008529</a>","short":"B. Kavcic, G. Tkačik, M.T. Bollenbach, PLOS Computational Biology 17 (2021).","ieee":"B. Kavcic, G. Tkačik, and M. T. Bollenbach, “Minimal biophysical model of combined antibiotic action,” <i>PLOS Computational Biology</i>, vol. 17. Public Library of Science, 2021."},"external_id":{"isi":["000608045000010"],"pmid":["33411759"]},"project":[{"call_identifier":"FWF","grant_number":"P27201-B22","name":"Revealing the mechanisms underlying drug interactions","_id":"25E9AF9E-B435-11E9-9278-68D0E5697425"},{"call_identifier":"FWF","grant_number":"P28844-B27","name":"Biophysics of information processing in gene regulation","_id":"254E9036-B435-11E9-9278-68D0E5697425"}],"acknowledgement":"This work was supported in part by Tum stipend of Knafelj foundation (to B.K.), Austrian Science Fund (FWF) standalone grants P 27201-B22 (to T.B.) and P 28844(to G.T.), HFSP program Grant RGP0042/2013 (to T.B.), German Research Foundation (DFG) individual grant BO 3502/2-1 (to T.B.), and German Research Foundation (DFG) Collaborative Research Centre (SFB) 1310 (to T.B.). ","volume":17,"publication_status":"published","department":[{"_id":"GaTk"}],"date_updated":"2026-07-06T12:44:35Z","article_type":"original","tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"file":[{"success":1,"file_name":"2021_PlosComBio_Kavcic.pdf","content_type":"application/pdf","relation":"main_file","checksum":"e29f2b42651bef8e034781de8781ffac","file_id":"9092","date_updated":"2021-02-04T12:30:48Z","access_level":"open_access","creator":"dernst","file_size":3690053,"date_created":"2021-02-04T12:30:48Z"}],"quality_controlled":"1","intvolume":"        17","language":[{"iso":"eng"}],"oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2021-01-08T07:16:18Z","date_published":"2021-01-07T00:00:00Z","type":"journal_article","has_accepted_license":"1","isi":1,"article_number":"e1008529","keyword":["Modelling and Simulation","Genetics","Molecular Biology","Antibiotics","Drug interactions"],"author":[{"id":"350F91D2-F248-11E8-B48F-1D18A9856A87","full_name":"Kavcic, Bor","orcid":"0000-0001-6041-254X","first_name":"Bor","last_name":"Kavcic"},{"orcid":"0000-0002-6699-1455","first_name":"Gašper","full_name":"Tkačik, Gašper","id":"3D494DCA-F248-11E8-B48F-1D18A9856A87","last_name":"Tkačik"},{"full_name":"Bollenbach, Tobias","id":"3E6DB97A-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-4398-476X","first_name":"Tobias","last_name":"Bollenbach"}],"pmid":1,"related_material":{"record":[{"relation":"research_data","id":"8930","status":"public"},{"status":"public","relation":"earlier_version","id":"7673"}]},"abstract":[{"text":"Phenomenological relations such as Ohm’s or Fourier’s law have a venerable history in physics but are still scarce in biology. This situation restrains predictive theory. Here, we build on bacterial “growth laws,” which capture physiological feedback between translation and cell growth, to construct a minimal biophysical model for the combined action of ribosome-targeting antibiotics. Our model predicts drug interactions like antagonism or synergy solely from responses to individual drugs. We provide analytical results for limiting cases, which agree well with numerical results. We systematically refine the model by including direct physical interactions of different antibiotics on the ribosome. In a limiting case, our model provides a mechanistic underpinning for recent predictions of higher-order interactions that were derived using entropy maximization. We further refine the model to include the effects of antibiotics that mimic starvation and the presence of resistance genes. We describe the impact of a starvation-mimicking antibiotic on drug interactions analytically and verify it experimentally. Our extended model suggests a change in the type of drug interaction that depends on the strength of resistance, which challenges established rescaling paradigms. We experimentally show that the presence of unregulated resistance genes can lead to altered drug interaction, which agrees with the prediction of the model. While minimal, the model is readily adaptable and opens the door to predicting interactions of second and higher-order in a broad range of biological systems.","lang":"eng"}],"day":"07","publication_identifier":{"issn":["1553-7358"]},"file_date_updated":"2021-02-04T12:30:48Z","doi":"10.1371/journal.pcbi.1008529","publisher":"Public Library of Science","ddc":["570"],"fulldoi":"https://doi.org/10.1371/journal.pcbi.1008529","scopus_import":"1","title":"Minimal biophysical model of combined antibiotic action","article_processing_charge":"Yes","oa":1,"_id":"8997","status":"public","month":"01","year":"2021","publication":"PLOS Computational Biology"}]