[{"oa_version":"Published Version","day":"02","has_accepted_license":"1","keyword":["natural selection"],"month":"01","type":"research_data","article_processing_charge":"No","publisher":"Institute of Science and Technology Austria","_id":"5559","abstract":[{"text":"Strong amplifiers of natural selection","lang":"eng"}],"status":"public","date_updated":"2025-04-15T08:12:19Z","project":[{"call_identifier":"FP7","_id":"2581B60A-B435-11E9-9278-68D0E5697425","name":"Quantitative Graph Games: Theory and Applications","grant_number":"279307"}],"author":[{"last_name":"Pavlogiannis","full_name":"Pavlogiannis, Andreas","id":"49704004-F248-11E8-B48F-1D18A9856A87","first_name":"Andreas","orcid":"0000-0002-8943-0722"},{"last_name":"Tkadlec","id":"3F24CCC8-F248-11E8-B48F-1D18A9856A87","full_name":"Tkadlec, Josef","first_name":"Josef","orcid":"0000-0002-1097-9684"},{"full_name":"Chatterjee, Krishnendu","id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","last_name":"Chatterjee","first_name":"Krishnendu","orcid":"0000-0002-4561-241X"},{"first_name":"Martin","full_name":"Nowak , Martin","last_name":"Nowak "}],"file":[{"date_created":"2018-12-12T13:05:18Z","file_name":"IST-2017-51-v1+2_illustration.mp4","content_type":"video/mp4","relation":"main_file","date_updated":"2020-07-14T12:47:02Z","creator":"system","checksum":"b427dd46a30096a1911b245640c47af8","file_size":32987015,"access_level":"open_access","file_id":"5644"}],"date_published":"2017-01-02T00:00:00Z","ddc":["519"],"department":[{"_id":"KrCh"}],"related_material":{"record":[{"id":"5452","relation":"research_paper","status":"public"},{"relation":"research_paper","id":"5751","status":"public"}]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file_date_updated":"2020-07-14T12:47:02Z","ec_funded":1,"title":"Strong amplifiers of natural selection","datarep_id":"51","citation":{"chicago":"Pavlogiannis, Andreas, Josef Tkadlec, Krishnendu Chatterjee, and Martin Nowak . “Strong Amplifiers of Natural Selection.” Institute of Science and Technology Austria, 2017. <a href=\"https://doi.org/10.15479/AT:ISTA:51\">https://doi.org/10.15479/AT:ISTA:51</a>.","apa":"Pavlogiannis, A., Tkadlec, J., Chatterjee, K., &#38; Nowak , M. (2017). Strong amplifiers of natural selection. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:51\">https://doi.org/10.15479/AT:ISTA:51</a>","ista":"Pavlogiannis A, Tkadlec J, Chatterjee K, Nowak  M. 2017. Strong amplifiers of natural selection, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:51\">10.15479/AT:ISTA:51</a>.","ama":"Pavlogiannis A, Tkadlec J, Chatterjee K, Nowak  M. Strong amplifiers of natural selection. 2017. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:51\">10.15479/AT:ISTA:51</a>","mla":"Pavlogiannis, Andreas, et al. <i>Strong Amplifiers of Natural Selection</i>. Institute of Science and Technology Austria, 2017, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:51\">10.15479/AT:ISTA:51</a>.","ieee":"A. Pavlogiannis, J. Tkadlec, K. Chatterjee, and M. Nowak , “Strong amplifiers of natural selection.” Institute of Science and Technology Austria, 2017.","short":"A. Pavlogiannis, J. Tkadlec, K. Chatterjee, M. Nowak , (2017)."},"oa":1,"date_created":"2018-12-12T12:31:32Z","doi":"10.15479/AT:ISTA:51","year":"2017"},{"citation":{"ieee":"T. Bergmiller <i>et al.</i>, “Biased partitioning of the multi-drug efflux pump AcrAB-TolC underlies long-lived phenotypic heterogeneity.” Institute of Science and Technology Austria, 2017.","mla":"Bergmiller, Tobias, et al. <i>Biased Partitioning of the Multi-Drug Efflux Pump AcrAB-TolC Underlies Long-Lived Phenotypic Heterogeneity</i>. Institute of Science and Technology Austria, 2017, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:53\">10.15479/AT:ISTA:53</a>.","short":"T. Bergmiller, A.M. Andersson, K. Tomasek, E. Balleza, D. Kiviet, R. Hauschild, G. Tkačik, C.C. Guet, (2017).","apa":"Bergmiller, T., Andersson, A. M., Tomasek, K., Balleza, E., Kiviet, D., Hauschild, R., … Guet, C. C. (2017). Biased partitioning of the multi-drug efflux pump AcrAB-TolC underlies long-lived phenotypic heterogeneity. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:53\">https://doi.org/10.15479/AT:ISTA:53</a>","chicago":"Bergmiller, Tobias, Anna M Andersson, Kathrin Tomasek, Enrique Balleza, Daniel Kiviet, Robert Hauschild, Gašper Tkačik, and Calin C Guet. “Biased Partitioning of the Multi-Drug Efflux Pump AcrAB-TolC Underlies Long-Lived Phenotypic Heterogeneity.” Institute of Science and Technology Austria, 2017. <a href=\"https://doi.org/10.15479/AT:ISTA:53\">https://doi.org/10.15479/AT:ISTA:53</a>.","ama":"Bergmiller T, Andersson AM, Tomasek K, et al. Biased partitioning of the multi-drug efflux pump AcrAB-TolC underlies long-lived phenotypic heterogeneity. 2017. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:53\">10.15479/AT:ISTA:53</a>","ista":"Bergmiller T, Andersson AM, Tomasek K, Balleza E, Kiviet D, Hauschild R, Tkačik G, Guet CC. 2017. Biased partitioning of the multi-drug efflux pump AcrAB-TolC underlies long-lived phenotypic heterogeneity, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:53\">10.15479/AT:ISTA:53</a>."},"license":"https://creativecommons.org/publicdomain/zero/1.0/","oa":1,"date_created":"2018-12-12T12:31:32Z","doi":"10.15479/AT:ISTA:53","year":"2017","tmp":{"short":"CC0 (1.0)","name":"Creative Commons Public Domain Dedication (CC0 1.0)","legal_code_url":"https://creativecommons.org/publicdomain/zero/1.0/legalcode","image":"/images/cc_0.png"},"related_material":{"record":[{"status":"public","relation":"research_paper","id":"665"}]},"department":[{"_id":"CaGu"},{"_id":"GaTk"},{"_id":"Bio"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file_date_updated":"2020-07-14T12:47:03Z","title":"Biased partitioning of the multi-drug efflux pump AcrAB-TolC underlies long-lived phenotypic heterogeneity","datarep_id":"53","_id":"5560","abstract":[{"text":"This repository contains the data collected for the manuscript \"Biased partitioning of the multi-drug efflux pump AcrAB-TolC underlies long-lived phenotypic heterogeneity\".\r\nThe data is compressed into a single archive. Within the archive, different folders correspond to figures of the main text and the SI of the related publication.\r\nData is saved as plain text, with each folder containing a separate readme file describing the format. Typically, the data is from fluorescence microscopy measurements of single cells growing in a microfluidic \"mother machine\" device, and consists of relevant values (primarily arbitrary unit or normalized fluorescence measurements, and division times / growth rates) after raw microscopy images have been processed, segmented, and their features extracted, as described in the methods section of the related publication.","lang":"eng"}],"status":"public","date_updated":"2025-09-11T07:05:03Z","author":[{"last_name":"Bergmiller","id":"2C471CFA-F248-11E8-B48F-1D18A9856A87","full_name":"Bergmiller, Tobias","first_name":"Tobias","orcid":"0000-0001-5396-4346"},{"full_name":"Andersson, Anna M","last_name":"Andersson","id":"2B8A40DA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2912-6769","first_name":"Anna M"},{"first_name":"Kathrin","orcid":"0000-0003-3768-877X","id":"3AEC8556-F248-11E8-B48F-1D18A9856A87","last_name":"Tomasek","full_name":"Tomasek, Kathrin"},{"full_name":"Balleza, Enrique","last_name":"Balleza","first_name":"Enrique"},{"first_name":"Daniel","full_name":"Kiviet, Daniel","last_name":"Kiviet"},{"orcid":"0000-0001-9843-3522","first_name":"Robert","last_name":"Hauschild","id":"4E01D6B4-F248-11E8-B48F-1D18A9856A87","full_name":"Hauschild, Robert"},{"full_name":"Tkacik, Gasper","last_name":"Tkacik","id":"3D494DCA-F248-11E8-B48F-1D18A9856A87","first_name":"Gasper","orcid":"0000-0002-6699-1455"},{"id":"47F8433E-F248-11E8-B48F-1D18A9856A87","full_name":"Guet, Calin C","last_name":"Guet","first_name":"Calin C","orcid":"0000-0001-6220-2052"}],"file":[{"access_level":"open_access","file_id":"5603","file_size":6773204,"checksum":"d77859af757ac8025c50c7b12b52eaf3","date_updated":"2020-07-14T12:47:03Z","creator":"system","date_created":"2018-12-12T13:02:38Z","file_name":"IST-2017-53-v1+1_Data_MDE.zip","content_type":"application/zip","relation":"main_file"}],"date_published":"2017-03-10T00:00:00Z","ddc":["571"],"oa_version":"Published Version","day":"10","keyword":["single cell microscopy","mother machine microfluidic device","AcrAB-TolC pump","multi-drug efflux","Escherichia coli"],"has_accepted_license":"1","month":"03","type":"research_data","article_processing_charge":"No","publisher":"Institute of Science and Technology Austria"},{"datarep_id":"57","file_date_updated":"2020-07-14T12:47:03Z","title":"Graph matching problems for annotating C. Elegans","department":[{"_id":"VlKo"}],"tmp":{"short":"CC0 (1.0)","name":"Creative Commons Public Domain Dedication (CC0 1.0)","legal_code_url":"https://creativecommons.org/publicdomain/zero/1.0/legalcode","image":"/images/cc_0.png"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2018-12-12T12:31:32Z","doi":"10.15479/AT:ISTA:57","year":"2017","oa":1,"citation":{"chicago":"Kainmueller, Dagmar, Florian Jug, Carsten Rother, and Gene Meyers. “Graph Matching Problems for Annotating C. Elegans.” Institute of Science and Technology Austria, 2017. <a href=\"https://doi.org/10.15479/AT:ISTA:57\">https://doi.org/10.15479/AT:ISTA:57</a>.","apa":"Kainmueller, D., Jug, F., Rother, C., &#38; Meyers, G. (2017). Graph matching problems for annotating C. Elegans. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:57\">https://doi.org/10.15479/AT:ISTA:57</a>","ista":"Kainmueller D, Jug F, Rother C, Meyers G. 2017. Graph matching problems for annotating C. Elegans, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:57\">10.15479/AT:ISTA:57</a>.","ama":"Kainmueller D, Jug F, Rother C, Meyers G. Graph matching problems for annotating C. Elegans. 2017. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:57\">10.15479/AT:ISTA:57</a>","short":"D. Kainmueller, F. Jug, C. Rother, G. Meyers, (2017).","mla":"Kainmueller, Dagmar, et al. <i>Graph Matching Problems for Annotating C. Elegans</i>. Institute of Science and Technology Austria, 2017, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:57\">10.15479/AT:ISTA:57</a>.","ieee":"D. Kainmueller, F. Jug, C. Rother, and G. Meyers, “Graph matching problems for annotating C. Elegans.” Institute of Science and Technology Austria, 2017."},"acknowledgement":"We thank Vladimir Kolmogorov and Stephan Saalfeld forinspiring discussions.","publisher":"Institute of Science and Technology Austria","article_processing_charge":"No","month":"02","type":"research_data","oa_version":"Published Version","keyword":["graph matching","feature matching","QAP","MAP-inference"],"has_accepted_license":"1","day":"13","date_published":"2017-02-13T00:00:00Z","ddc":["000"],"file":[{"file_id":"5614","access_level":"open_access","file_size":327042819,"checksum":"3dc3e1306a66028a34181ebef2923139","creator":"system","date_updated":"2020-07-14T12:47:03Z","content_type":"application/zip","relation":"main_file","file_name":"IST-2017-57-v1+1_wormMatchingProblems.zip","date_created":"2018-12-12T13:02:54Z"}],"author":[{"first_name":"Dagmar","full_name":"Kainmueller, Dagmar","last_name":"Kainmueller"},{"last_name":"Jug","full_name":"Jug, Florian","first_name":"Florian"},{"full_name":"Rother, Carsten","last_name":"Rother","first_name":"Carsten"},{"full_name":"Meyers, Gene","last_name":"Meyers","first_name":"Gene"}],"_id":"5561","abstract":[{"lang":"eng","text":"Graph matching problems as described in \"Active Graph Matching for Automatic Joint Segmentation and Annotation of C. Elegans.\" by Kainmueller, Dagmar and Jug, Florian and Rother, Carsten and Myers, Gene, MICCAI 2014. Problems are in OpenGM2 hdf5 format (see http://hciweb2.iwr.uni-heidelberg.de/opengm/) and a custom text format used by the feature matching solver described in \"Feature Correspondence via Graph Matching: Models and Global Optimization.\" by Lorenzo Torresani, Vladimir Kolmogorov and Carsten Rother, ECCV 2008, code at http://pub.ist.ac.at/~vnk/software/GraphMatching-v1.02.src.zip. "}],"date_updated":"2024-02-21T13:46:31Z","status":"public"},{"datarep_id":"61","title":"Multi-electrode array recording from salamander retinal ganglion cells","file_date_updated":"2020-07-14T12:47:03Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","tmp":{"short":"CC0 (1.0)","name":"Creative Commons Public Domain Dedication (CC0 1.0)","legal_code_url":"https://creativecommons.org/publicdomain/zero/1.0/legalcode","image":"/images/cc_0.png"},"related_material":{"record":[{"id":"2257","relation":"used_in_publication","status":"public"}]},"department":[{"_id":"GaTk"}],"year":"2017","doi":"10.15479/AT:ISTA:61","date_created":"2018-12-12T12:31:33Z","oa":1,"citation":{"ieee":"O. Marre, G. Tkačik, D. Amodei, E. Schneidman, W. Bialek, and M. Berry, “Multi-electrode array recording from salamander retinal ganglion cells.” Institute of Science and Technology Austria, 2017.","short":"O. Marre, G. Tkačik, D. Amodei, E. Schneidman, W. Bialek, M. Berry, (2017).","mla":"Marre, Olivier, et al. <i>Multi-Electrode Array Recording from Salamander Retinal Ganglion Cells</i>. Institute of Science and Technology Austria, 2017, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:61\">10.15479/AT:ISTA:61</a>.","chicago":"Marre, Olivier, Gašper Tkačik, Dario Amodei, Elad Schneidman, William Bialek, and Michael Berry. “Multi-Electrode Array Recording from Salamander Retinal Ganglion Cells.” Institute of Science and Technology Austria, 2017. <a href=\"https://doi.org/10.15479/AT:ISTA:61\">https://doi.org/10.15479/AT:ISTA:61</a>.","apa":"Marre, O., Tkačik, G., Amodei, D., Schneidman, E., Bialek, W., &#38; Berry, M. (2017). Multi-electrode array recording from salamander retinal ganglion cells. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:61\">https://doi.org/10.15479/AT:ISTA:61</a>","ista":"Marre O, Tkačik G, Amodei D, Schneidman E, Bialek W, Berry M. 2017. Multi-electrode array recording from salamander retinal ganglion cells, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:61\">10.15479/AT:ISTA:61</a>.","ama":"Marre O, Tkačik G, Amodei D, Schneidman E, Bialek W, Berry M. Multi-electrode array recording from salamander retinal ganglion cells. 2017. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:61\">10.15479/AT:ISTA:61</a>"},"publisher":"Institute of Science and Technology Austria","article_processing_charge":"No","type":"research_data","month":"02","day":"27","keyword":["multi-electrode recording","retinal ganglion cells"],"has_accepted_license":"1","oa_version":"Published Version","ddc":["570"],"date_published":"2017-02-27T00:00:00Z","author":[{"first_name":"Olivier","full_name":"Marre, Olivier","last_name":"Marre"},{"first_name":"Gasper","orcid":"0000-0002-6699-1455","id":"3D494DCA-F248-11E8-B48F-1D18A9856A87","last_name":"Tkacik","full_name":"Tkacik, Gasper"},{"first_name":"Dario","last_name":"Amodei","full_name":"Amodei, Dario"},{"first_name":"Elad","full_name":"Schneidman, Elad","last_name":"Schneidman"},{"first_name":"William","last_name":"Bialek","full_name":"Bialek, William"},{"first_name":"Michael","last_name":"Berry","full_name":"Berry, Michael"}],"file":[{"content_type":"application/octet-stream","relation":"main_file","date_created":"2018-12-12T13:03:04Z","file_name":"IST-2017-61-v1+1_bint_fishmovie32_100.mat","creator":"system","date_updated":"2020-07-14T12:47:03Z","checksum":"e620eff260646f57b479a69492c8b765","file_size":1336936,"file_id":"5622","access_level":"open_access"},{"content_type":"application/zip","relation":"main_file","file_name":"IST-2017-61-v1+2_bint_fishmovie32_100.zip","date_created":"2018-12-12T13:03:05Z","creator":"system","date_updated":"2020-07-14T12:47:03Z","file_size":1897543,"checksum":"de83f9b81ea0aae3cddfc3ed982e0759","file_id":"5623","access_level":"open_access"}],"status":"public","date_updated":"2025-09-29T11:14:05Z","_id":"5562","abstract":[{"lang":"eng","text":"This data was collected as part of the study [1]. It consists of preprocessed multi-electrode array recording from 160 salamander retinal ganglion cells responding to 297 repeats of a 19 s natural movie. The data is available in two formats: (1) a .mat file containing an array with dimensions “number of repeats” x “number of neurons” x “time in a repeat”; (2) a zipped .txt file containing the same data represented as an array with dimensions “number of neurons” x “number of samples”, where the number of samples is equal to the product of the number of repeats and timebins within a repeat. The time dimension is divided into 20 ms time windows, and the array is binary indicating whether a given cell elicited at least one spike in a given time window during a particular repeat. See the reference below for details regarding collection and preprocessing:\r\n\r\n[1] Tkačik G, Marre O, Amodei D, Schneidman E, Bialek W, Berry MJ II. Searching for Collective Behavior in a Large Network of Sensory Neurons. PLoS Comput Biol. 2014;10(1):e1003408."}]},{"status":"public","date_updated":"2024-02-21T13:46:47Z","abstract":[{"lang":"eng","text":"MATLAB code and processed datasets available for reproducing the results in: \r\nLukačišin, M.*, Landon, M.*, Jajoo, R*. (2016) Sequence-Specific Thermodynamic Properties of Nucleic Acids Influence Both Transcriptional Pausing and Backtracking in Yeast.\r\n*equal contributions"}],"_id":"5563","ddc":["571"],"date_published":"2017-03-20T00:00:00Z","author":[{"full_name":"Lukacisin, Martin","id":"298FFE8C-F248-11E8-B48F-1D18A9856A87","last_name":"Lukacisin","orcid":"0000-0001-6549-4177","first_name":"Martin"}],"file":[{"file_id":"5602","access_level":"open_access","file_size":296722548,"checksum":"ee697f2b1ade4dc14d6ac0334dd832ab","creator":"system","date_updated":"2020-07-14T12:47:03Z","relation":"main_file","content_type":"application/zip","date_created":"2018-12-12T13:02:37Z","file_name":"IST-2016-45-v1+1_PaperCode.zip"}],"type":"research_data","month":"03","has_accepted_license":"1","day":"20","oa_version":"Published Version","publisher":"Institute of Science and Technology Austria","article_processing_charge":"No","oa":1,"license":"https://creativecommons.org/licenses/by-sa/4.0/","citation":{"ieee":"M. Lukacisin, “MATLAB analysis code for ‘Sequence-Specific Thermodynamic Properties of Nucleic Acids Influence Both Transcriptional Pausing and Backtracking in Yeast.’” Institute of Science and Technology Austria, 2017.","short":"M. Lukacisin, (2017).","mla":"Lukacisin, Martin. <i>MATLAB Analysis Code for “Sequence-Specific Thermodynamic Properties of Nucleic Acids Influence Both Transcriptional Pausing and Backtracking in Yeast.”</i> Institute of Science and Technology Austria, 2017, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:64\">10.15479/AT:ISTA:64</a>.","chicago":"Lukacisin, Martin. “MATLAB Analysis Code for ‘Sequence-Specific Thermodynamic Properties of Nucleic Acids Influence Both Transcriptional Pausing and Backtracking in Yeast.’” Institute of Science and Technology Austria, 2017. <a href=\"https://doi.org/10.15479/AT:ISTA:64\">https://doi.org/10.15479/AT:ISTA:64</a>.","apa":"Lukacisin, M. (2017). MATLAB analysis code for “Sequence-Specific Thermodynamic Properties of Nucleic Acids Influence Both Transcriptional Pausing and Backtracking in Yeast.” Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:64\">https://doi.org/10.15479/AT:ISTA:64</a>","ista":"Lukacisin M. 2017. MATLAB analysis code for ‘Sequence-Specific Thermodynamic Properties of Nucleic Acids Influence Both Transcriptional Pausing and Backtracking in Yeast’, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:64\">10.15479/AT:ISTA:64</a>.","ama":"Lukacisin M. MATLAB analysis code for “Sequence-Specific Thermodynamic Properties of Nucleic Acids Influence Both Transcriptional Pausing and Backtracking in Yeast.” 2017. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:64\">10.15479/AT:ISTA:64</a>"},"year":"2017","date_created":"2018-12-12T12:31:33Z","doi":"10.15479/AT:ISTA:64","title":"MATLAB analysis code for 'Sequence-Specific Thermodynamic Properties of Nucleic Acids Influence Both Transcriptional Pausing and Backtracking in Yeast'","file_date_updated":"2020-07-14T12:47:03Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","tmp":{"image":"/images/cc_by_sa.png","name":"Creative Commons Attribution-ShareAlike 4.0 International Public License (CC BY-SA 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","short":"CC BY-SA (4.0)"},"department":[{"_id":"ToBo"}],"datarep_id":"64"},{"abstract":[{"lang":"eng","text":"Compressed Fastq files with whole-genome sequencing data of IS-wt strain D and clones from four evolved populations (A11, C08, C10, D08). Information on this data collection is available in the Methods Section of the primary publication."}],"_id":"5564","date_updated":"2025-09-10T11:06:52Z","status":"public","file":[{"access_level":"open_access","file_id":"5627","file_size":1225959109,"checksum":"31a0c01d022721073241a23d192cc37e","date_updated":"2020-07-14T12:47:03Z","creator":"system","date_created":"2018-12-12T13:03:18Z","file_name":"IST-2017-65-v1+1_D_anc_1.fastq.zip","relation":"main_file","content_type":"application/zip"},{"file_id":"5628","access_level":"open_access","file_size":1422656107,"checksum":"d8f26f83ce7e7e45436121f9c6cd9b83","creator":"system","date_updated":"2020-07-14T12:47:03Z","relation":"main_file","content_type":"application/zip","date_created":"2018-12-12T13:03:30Z","file_name":"IST-2017-65-v1+1_D_anc_2.fastq.zip"},{"file_id":"5629","access_level":"open_access","checksum":"e07b99bcfe55b5f132ca03b8b48c8cbc","file_size":565014975,"creator":"system","date_updated":"2020-07-14T12:47:03Z","content_type":"application/zip","relation":"main_file","file_name":"IST-2017-65-v1+2_D_A11_1.fastq.zip","date_created":"2018-12-12T13:03:33Z"},{"file_id":"5630","access_level":"open_access","checksum":"eda86143d5f32d844b54f8530041e32b","file_size":564490030,"creator":"system","date_updated":"2020-07-14T12:47:03Z","content_type":"application/zip","relation":"main_file","date_created":"2018-12-12T13:03:42Z","file_name":"IST-2017-65-v1+3_D_A11_2.fastq.zip"},{"checksum":"906d44f950c1626d9b99f34fbf89cb12","file_size":875430169,"access_level":"open_access","file_id":"5631","file_name":"IST-2017-65-v1+4_D_C10_1.fastq.zip","date_created":"2018-12-12T13:03:46Z","relation":"main_file","content_type":"application/zip","date_updated":"2020-07-14T12:47:03Z","creator":"system"},{"file_name":"IST-2017-65-v1+6_D_C08_2.fastq.zip","date_created":"2018-12-12T13:03:54Z","content_type":"application/zip","relation":"main_file","date_updated":"2020-07-14T12:47:03Z","creator":"system","checksum":"6ca14a032a79e0c787106bdf635725c9","file_size":638298201,"access_level":"open_access","file_id":"5632"},{"file_name":"IST-2017-65-v1+5_D_C10_2.fastq.zip","date_created":"2018-12-12T13:04:01Z","relation":"main_file","content_type":"application/zip","date_updated":"2020-07-14T12:47:03Z","creator":"system","file_size":894702866,"checksum":"66ab16ddb5ba64b2e263ef746ebf2893","access_level":"open_access","file_id":"5633"},{"date_created":"2018-12-12T13:04:07Z","file_name":"IST-2017-65-v1+7_D_C08_1.fastq.zip","relation":"main_file","content_type":"application/zip","date_updated":"2020-07-14T12:47:03Z","creator":"system","file_size":623648989,"checksum":"82607970174f8d37773b7d3acc712195","access_level":"open_access","file_id":"5634"},{"file_id":"5635","access_level":"open_access","checksum":"225c30b243268c7dda9d6f8327933252","file_size":259359583,"creator":"system","date_updated":"2020-07-14T12:47:03Z","content_type":"application/zip","relation":"main_file","date_created":"2018-12-12T13:04:11Z","file_name":"IST-2017-65-v1+8_D_D08_1.fastq.zip"}],"author":[{"last_name":"Steinrück","full_name":"Steinrück, Magdalena","id":"2C023F40-F248-11E8-B48F-1D18A9856A87","first_name":"Magdalena","orcid":"0000-0003-1229-9719"},{"first_name":"Calin C","orcid":"0000-0001-6220-2052","id":"47F8433E-F248-11E8-B48F-1D18A9856A87","last_name":"Guet","full_name":"Guet, Calin C"}],"date_published":"2017-04-11T00:00:00Z","ddc":["576"],"oa_version":"Published Version","day":"11","has_accepted_license":"1","month":"04","type":"research_data","article_processing_charge":"No","publisher":"Institute of Science and Technology Austria","citation":{"chicago":"Steinrück, Magdalena, and Calin C Guet. “Fastq Files for ‘Complex Chromosomal Neighborhood Effects Determine the Adaptive Potential of a Gene under Selection.’” Institute of Science and Technology Austria, 2017. <a href=\"https://doi.org/10.15479/AT:ISTA:65\">https://doi.org/10.15479/AT:ISTA:65</a>.","apa":"Steinrück, M., &#38; Guet, C. C. (2017). Fastq files for “Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection.” Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:65\">https://doi.org/10.15479/AT:ISTA:65</a>","ista":"Steinrück M, Guet CC. 2017. Fastq files for ‘Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection’, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:65\">10.15479/AT:ISTA:65</a>.","ama":"Steinrück M, Guet CC. Fastq files for “Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection.” 2017. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:65\">10.15479/AT:ISTA:65</a>","short":"M. Steinrück, C.C. Guet, (2017).","ieee":"M. Steinrück and C. C. Guet, “Fastq files for ‘Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection.’” Institute of Science and Technology Austria, 2017.","mla":"Steinrück, Magdalena, and Calin C. Guet. <i>Fastq Files for “Complex Chromosomal Neighborhood Effects Determine the Adaptive Potential of a Gene under Selection.”</i> Institute of Science and Technology Austria, 2017, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:65\">10.15479/AT:ISTA:65</a>."},"oa":1,"doi":"10.15479/AT:ISTA:65","date_created":"2018-12-12T12:31:33Z","year":"2017","tmp":{"short":"CC0 (1.0)","name":"Creative Commons Public Domain Dedication (CC0 1.0)","legal_code_url":"https://creativecommons.org/publicdomain/zero/1.0/legalcode","image":"/images/cc_0.png"},"related_material":{"record":[{"relation":"research_paper","id":"704","status":"public"}]},"department":[{"_id":"CaGu"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file_date_updated":"2020-07-14T12:47:03Z","title":"Fastq files for \"Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection\"","datarep_id":"65"},{"related_material":{"record":[{"relation":"research_paper","id":"1078","status":"public"}]},"department":[{"_id":"JiFr"},{"_id":"Bio"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file_date_updated":"2020-07-14T12:47:03Z","title":"Light Sheet Fluorescence microscopy of plant roots growing on the surface of a gel","ec_funded":1,"publist_id":"6302","datarep_id":"66","citation":{"mla":"von Wangenheim, Daniel, et al. <i>Light Sheet Fluorescence Microscopy of Plant Roots Growing on the Surface of a Gel</i>. Institute of Science and Technology Austria, 2017, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:66\">10.15479/AT:ISTA:66</a>.","ieee":"D. von Wangenheim, R. Hauschild, and J. Friml, “Light Sheet Fluorescence microscopy of plant roots growing on the surface of a gel.” Institute of Science and Technology Austria, 2017.","short":"D. von Wangenheim, R. Hauschild, J. Friml, (2017).","ista":"von Wangenheim D, Hauschild R, Friml J. 2017. Light Sheet Fluorescence microscopy of plant roots growing on the surface of a gel, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:66\">10.15479/AT:ISTA:66</a>.","ama":"von Wangenheim D, Hauschild R, Friml J. Light Sheet Fluorescence microscopy of plant roots growing on the surface of a gel. 2017. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:66\">10.15479/AT:ISTA:66</a>","chicago":"Wangenheim, Daniel von, Robert Hauschild, and Jiří Friml. “Light Sheet Fluorescence Microscopy of Plant Roots Growing on the Surface of a Gel.” Institute of Science and Technology Austria, 2017. <a href=\"https://doi.org/10.15479/AT:ISTA:66\">https://doi.org/10.15479/AT:ISTA:66</a>.","apa":"von Wangenheim, D., Hauschild, R., &#38; Friml, J. (2017). Light Sheet Fluorescence microscopy of plant roots growing on the surface of a gel. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:66\">https://doi.org/10.15479/AT:ISTA:66</a>"},"acknowledgement":"fund: FP7-ERC 0101109","oa":1,"doi":"10.15479/AT:ISTA:66","date_created":"2018-12-12T12:31:34Z","year":"2017","oa_version":"Published Version","has_accepted_license":"1","day":"10","month":"04","type":"research_data","article_processing_charge":"No","publisher":"Institute of Science and Technology Austria","abstract":[{"lang":"eng","text":"One of the key questions in understanding plant development is how single cells behave in a larger context of the tissue. Therefore, it requires the observation of the whole organ with a high spatial- as well as temporal resolution over prolonged periods of time, which may cause photo-toxic effects. This protocol shows a plant sample preparation method for light-sheet microscopy, which is characterized by mounting the plant vertically on the surface of a gel. The plant is mounted in such a way that the roots are submerged in a liquid medium while the leaves remain in the air. In order to ensure photosynthetic activity of the plant, a custom-made lighting system illuminates the leaves. To keep the roots in darkness the water surface is covered with sheets of black plastic foil. This method allows long-term imaging of plant organ development in standardized conditions. \r\nThe Video is licensed under a CC BY NC ND license. "}],"_id":"5565","date_updated":"2025-04-15T07:48:04Z","status":"public","project":[{"call_identifier":"FP7","_id":"25681D80-B435-11E9-9278-68D0E5697425","name":"International IST Postdoc Fellowship Programme","grant_number":"291734"}],"author":[{"orcid":"0000-0002-6862-1247","first_name":"Daniel","full_name":"Von Wangenheim, Daniel","id":"49E91952-F248-11E8-B48F-1D18A9856A87","last_name":"Von Wangenheim"},{"orcid":"0000-0001-9843-3522","first_name":"Robert","id":"4E01D6B4-F248-11E8-B48F-1D18A9856A87","full_name":"Hauschild, Robert","last_name":"Hauschild"},{"first_name":"Jirí","orcid":"0000-0002-8302-7596","last_name":"Friml","full_name":"Friml, Jirí","id":"4159519E-F248-11E8-B48F-1D18A9856A87"}],"file":[{"content_type":"video/mp4","relation":"main_file","file_name":"IST-2017-66-v1+1_WangenheimHighResolution55044-NEW_1.mp4","date_created":"2018-12-12T13:02:33Z","creator":"system","date_updated":"2020-07-14T12:47:03Z","file_size":101497758,"checksum":"b7552fc23540a85dc5a22fd4484eae71","file_id":"5599","access_level":"open_access"}],"date_published":"2017-04-10T00:00:00Z","ddc":["580"]},{"date_created":"2018-12-12T12:31:34Z","doi":"10.15479/AT:ISTA:69","year":"2017","oa":1,"citation":{"apa":"Hauschild, R. (2017). Live tracking of moving samples in confocal microscopy for vertically grown roots. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:69\">https://doi.org/10.15479/AT:ISTA:69</a>","chicago":"Hauschild, Robert. “Live Tracking of Moving Samples in Confocal Microscopy for Vertically Grown Roots.” Institute of Science and Technology Austria, 2017. <a href=\"https://doi.org/10.15479/AT:ISTA:69\">https://doi.org/10.15479/AT:ISTA:69</a>.","ama":"Hauschild R. Live tracking of moving samples in confocal microscopy for vertically grown roots. 2017. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:69\">10.15479/AT:ISTA:69</a>","ista":"Hauschild R. 2017. Live tracking of moving samples in confocal microscopy for vertically grown roots, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:69\">10.15479/AT:ISTA:69</a>.","mla":"Hauschild, Robert. <i>Live Tracking of Moving Samples in Confocal Microscopy for Vertically Grown Roots</i>. Institute of Science and Technology Austria, 2017, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:69\">10.15479/AT:ISTA:69</a>.","short":"R. Hauschild, (2017).","ieee":"R. Hauschild, “Live tracking of moving samples in confocal microscopy for vertically grown roots.” Institute of Science and Technology Austria, 2017."},"datarep_id":"69","file_date_updated":"2020-07-14T12:47:04Z","title":"Live tracking of moving samples in confocal microscopy for vertically grown roots","related_material":{"record":[{"relation":"research_paper","id":"946","status":"public"}]},"tmp":{"image":"/images/cc_by_sa.png","name":"Creative Commons Attribution-ShareAlike 4.0 International Public License (CC BY-SA 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","short":"CC BY-SA (4.0)"},"department":[{"_id":"Bio"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2017-07-21T00:00:00Z","ddc":["570"],"author":[{"first_name":"Robert","orcid":"0000-0001-9843-3522","last_name":"Hauschild","full_name":"Hauschild, Robert","id":"4E01D6B4-F248-11E8-B48F-1D18A9856A87"}],"file":[{"file_name":"IST-2017-69-v1+2_TipTrackerZeissLSM700.zip","date_created":"2018-12-12T13:04:12Z","relation":"main_file","content_type":"application/zip","date_updated":"2020-07-14T12:47:04Z","creator":"system","checksum":"a976000e6715106724a271cc9422be4a","file_size":1587986,"access_level":"open_access","file_id":"5636"}],"abstract":[{"text":"Current minimal version of TipTracker","lang":"eng"}],"_id":"5566","status":"public","date_updated":"2025-04-15T07:48:05Z","publisher":"Institute of Science and Technology Austria","article_processing_charge":"No","month":"07","type":"research_data","oa_version":"Published Version","keyword":["tool","tracking","confocal microscopy"],"has_accepted_license":"1","day":"21"},{"citation":{"mla":"Leithner, Alexander F. <i>Immunological Synapse DC-Tcells</i>. Institute of Science and Technology Austria, 2017, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:71\">10.15479/AT:ISTA:71</a>.","short":"A.F. Leithner, (2017).","ieee":"A. F. Leithner, “Immunological synapse DC-Tcells.” Institute of Science and Technology Austria, 2017.","apa":"Leithner, A. F. (2017). Immunological synapse DC-Tcells. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:71\">https://doi.org/10.15479/AT:ISTA:71</a>","chicago":"Leithner, Alexander F. “Immunological Synapse DC-Tcells.” Institute of Science and Technology Austria, 2017. <a href=\"https://doi.org/10.15479/AT:ISTA:71\">https://doi.org/10.15479/AT:ISTA:71</a>.","ama":"Leithner AF. Immunological synapse DC-Tcells. 2017. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:71\">10.15479/AT:ISTA:71</a>","ista":"Leithner AF. 2017. Immunological synapse DC-Tcells, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:71\">10.15479/AT:ISTA:71</a>."},"oa":1,"date_created":"2018-12-12T12:31:34Z","doi":"10.15479/AT:ISTA:71","year":"2017","tmp":{"short":"CC0 (1.0)","name":"Creative Commons Public Domain Dedication (CC0 1.0)","legal_code_url":"https://creativecommons.org/publicdomain/zero/1.0/legalcode","image":"/images/cc_0.png"},"department":[{"_id":"MiSi"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file_date_updated":"2020-07-14T12:47:04Z","title":"Immunological synapse DC-Tcells","datarep_id":"71","_id":"5567","abstract":[{"lang":"eng","text":"Immunological synapse DC-Tcells"}],"status":"public","date_updated":"2024-02-21T13:47:00Z","file":[{"file_id":"5612","access_level":"open_access","file_size":236204020,"checksum":"3d6942d47d0737d064706b5728c4d8c8","creator":"system","date_updated":"2020-07-14T12:47:04Z","relation":"main_file","content_type":"video/x-msvideo","date_created":"2018-12-12T13:02:47Z","file_name":"IST-2017-71-v1+1_Synapse_1.avi"},{"access_level":"open_access","file_id":"5613","file_size":226232496,"checksum":"4850006c047b0147a9e85b3c2f6f0af4","date_updated":"2020-07-14T12:47:04Z","creator":"system","file_name":"IST-2017-71-v1+2_Synapse_2.avi","date_created":"2018-12-12T13:02:51Z","relation":"main_file","content_type":"video/x-msvideo"}],"author":[{"first_name":"Alexander F","orcid":"0000-0002-1073-744X","last_name":"Leithner","full_name":"Leithner, Alexander F","id":"3B1B77E4-F248-11E8-B48F-1D18A9856A87"}],"date_published":"2017-08-09T00:00:00Z","ddc":["570"],"oa_version":"Published Version","has_accepted_license":"1","keyword":["Immunological synapse"],"day":"09","month":"08","type":"research_data","article_processing_charge":"No","publisher":"Institute of Science and Technology Austria"},{"year":"2017","doi":"10.15479/AT:ISTA:75","date_created":"2018-12-12T12:31:35Z","oa":1,"citation":{"short":"R. Hauschild, (2017).","ieee":"R. Hauschild, “Forward migration indexes.” Institute of Science and Technology Austria, 2017.","mla":"Hauschild, Robert. <i>Forward Migration Indexes</i>. Institute of Science and Technology Austria, 2017, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:75\">10.15479/AT:ISTA:75</a>.","chicago":"Hauschild, Robert. “Forward Migration Indexes.” Institute of Science and Technology Austria, 2017. <a href=\"https://doi.org/10.15479/AT:ISTA:75\">https://doi.org/10.15479/AT:ISTA:75</a>.","apa":"Hauschild, R. (2017). Forward migration indexes. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:75\">https://doi.org/10.15479/AT:ISTA:75</a>","ista":"Hauschild R. 2017. Forward migration indexes, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:75\">10.15479/AT:ISTA:75</a>.","ama":"Hauschild R. Forward migration indexes. 2017. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:75\">10.15479/AT:ISTA:75</a>"},"datarep_id":"75","title":"Forward migration indexes","file_date_updated":"2020-07-14T12:47:04Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","tmp":{"short":"CC0 (1.0)","name":"Creative Commons Public Domain Dedication (CC0 1.0)","legal_code_url":"https://creativecommons.org/publicdomain/zero/1.0/legalcode","image":"/images/cc_0.png"},"department":[{"_id":"Bio"}],"ddc":["570"],"date_published":"2017-10-04T00:00:00Z","author":[{"id":"4E01D6B4-F248-11E8-B48F-1D18A9856A87","full_name":"Hauschild, Robert","last_name":"Hauschild","first_name":"Robert","orcid":"0000-0001-9843-3522"}],"file":[{"file_size":799,"checksum":"cb7a2fa622460eca6231d659ce590e32","access_level":"open_access","file_id":"5596","file_name":"IST-2017-75-v1+1_FMI.m","date_created":"2018-12-12T13:02:29Z","content_type":"application/octet-stream","relation":"main_file","date_updated":"2020-07-14T12:47:04Z","creator":"system"}],"status":"public","date_updated":"2024-02-21T13:47:14Z","abstract":[{"text":"Matlab script to calculate the forward migration indexes (<d_y>/<L>) from TrackMate spot-statistics files.","lang":"eng"}],"_id":"5570","publisher":"Institute of Science and Technology Austria","article_processing_charge":"No","type":"research_data","month":"10","day":"04","has_accepted_license":"1","keyword":["Cell migration","tracking","forward migration index","FMI"],"oa_version":"Published Version"},{"date_created":"2018-12-12T12:31:36Z","doi":"10.15479/AT:ISTA:78","year":"2017","citation":{"chicago":"Vicoso, Beatriz. “Data for ‘The Genomic Characterization of the t-Haplotype, a Mouse Meiotic Driver, Highlights Its Complex History and Specialized Biology.’” Institute of Science and Technology Austria, 2017. <a href=\"https://doi.org/10.15479/AT:ISTA:78\">https://doi.org/10.15479/AT:ISTA:78</a>.","apa":"Vicoso, B. (2017). Data for “The genomic characterization of the t-haplotype, a mouse meiotic driver, highlights its complex history and specialized biology.” Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:78\">https://doi.org/10.15479/AT:ISTA:78</a>","ista":"Vicoso B. 2017. Data for ‘The genomic characterization of the t-haplotype, a mouse meiotic driver, highlights its complex history and specialized biology’, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:78\">10.15479/AT:ISTA:78</a>.","ama":"Vicoso B. Data for “The genomic characterization of the t-haplotype, a mouse meiotic driver, highlights its complex history and specialized biology.” 2017. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:78\">10.15479/AT:ISTA:78</a>","ieee":"B. Vicoso, “Data for ‘The genomic characterization of the t-haplotype, a mouse meiotic driver, highlights its complex history and specialized biology.’” Institute of Science and Technology Austria, 2017.","mla":"Vicoso, Beatriz. <i>Data for “The Genomic Characterization of the t-Haplotype, a Mouse Meiotic Driver, Highlights Its Complex History and Specialized Biology.”</i> Institute of Science and Technology Austria, 2017, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:78\">10.15479/AT:ISTA:78</a>.","short":"B. Vicoso, (2017)."},"oa":1,"datarep_id":"78","tmp":{"short":"CC0 (1.0)","name":"Creative Commons Public Domain Dedication (CC0 1.0)","legal_code_url":"https://creativecommons.org/publicdomain/zero/1.0/legalcode","image":"/images/cc_0.png"},"department":[{"_id":"BeVi"}],"related_material":{"record":[{"status":"public","relation":"research_paper","id":"542"}]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file_date_updated":"2020-07-14T12:47:04Z","title":"Data for \"The genomic characterization of the t-haplotype, a mouse meiotic driver, highlights its complex history and specialized biology\"","author":[{"full_name":"Vicoso, Beatriz","last_name":"Vicoso","id":"49E1C5C6-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-4579-8306","first_name":"Beatriz"}],"file":[{"file_size":143697895,"checksum":"4520eb2b8379417ee916995719158f16","access_level":"open_access","file_id":"5618","date_created":"2018-12-12T13:03:00Z","file_name":"IST-2017-78-v1+1_Data.zip","relation":"main_file","content_type":"application/zip","date_updated":"2020-07-14T12:47:04Z","creator":"system"}],"date_published":"2017-11-06T00:00:00Z","ddc":["576"],"abstract":[{"lang":"eng","text":"This folder contains all the data used in each of the main figures of \"The genomic characterization of the t-haplotype, a mouse meiotic driver, highlights its complex history and specialized biology\" (Kelemen, R., Vicoso, B.), as well as in the supplementary figures. \r\n"}],"_id":"5571","status":"public","date_updated":"2025-04-15T07:49:49Z","article_processing_charge":"No","publisher":"Institute of Science and Technology Austria","oa_version":"Submitted Version","has_accepted_license":"1","day":"06","month":"11","contributor":[{"id":"49E1C5C6-F248-11E8-B48F-1D18A9856A87","last_name":"Vicoso","first_name":"Beatriz","contributor_type":"contact_person"}],"type":"research_data"},{"article_processing_charge":"No","publisher":"Institute of Science and Technology Austria","oa_version":"Submitted Version","day":"06","has_accepted_license":"1","month":"11","type":"research_data","file":[{"date_updated":"2020-07-14T12:47:05Z","creator":"system","date_created":"2018-12-12T13:05:15Z","file_name":"IST-2017-79-v1+1_Code.zip","relation":"main_file","content_type":"application/zip","access_level":"open_access","file_id":"5643","checksum":"3e70a7bcd6ff0c38b79e4c8a7d137034","file_size":49823}],"author":[{"last_name":"Vicoso","full_name":"Vicoso, Beatriz","id":"49E1C5C6-F248-11E8-B48F-1D18A9856A87","first_name":"Beatriz","orcid":"0000-0002-4579-8306"}],"date_published":"2017-11-06T00:00:00Z","ddc":["576"],"_id":"5572","abstract":[{"text":"Code described in the Supplementary Methods of \"The genomic characterization of the t-haplotype, a mouse meiotic driver, highlights its complex history and specialized biology\" (Kelemen, R., Vicoso, B.)","lang":"eng"}],"date_updated":"2025-04-15T07:49:49Z","status":"public","datarep_id":"79","related_material":{"record":[{"status":"public","id":"542","relation":"research_paper"}]},"tmp":{"short":"CC0 (1.0)","name":"Creative Commons Public Domain Dedication (CC0 1.0)","legal_code_url":"https://creativecommons.org/publicdomain/zero/1.0/legalcode","image":"/images/cc_0.png"},"department":[{"_id":"BeVi"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file_date_updated":"2020-07-14T12:47:05Z","title":"Code for \"The genomic characterization of the t-haplotype, a mouse meiotic driver, highlights its complex history and specialized biology\"","doi":"10.15479/AT:ISTA:79 ","date_created":"2018-12-12T12:31:36Z","year":"2017","citation":{"ieee":"B. Vicoso, “Code for ‘The genomic characterization of the t-haplotype, a mouse meiotic driver, highlights its complex history and specialized biology.’” Institute of Science and Technology Austria, 2017.","short":"B. Vicoso, (2017).","mla":"Vicoso, Beatriz. <i>Code for “The Genomic Characterization of the t-Haplotype, a Mouse Meiotic Driver, Highlights Its Complex History and Specialized Biology.”</i> Institute of Science and Technology Austria, 2017, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:79 \">10.15479/AT:ISTA:79 </a>.","ama":"Vicoso B. Code for “The genomic characterization of the t-haplotype, a mouse meiotic driver, highlights its complex history and specialized biology.” 2017. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:79 \">10.15479/AT:ISTA:79 </a>","ista":"Vicoso B. 2017. Code for ‘The genomic characterization of the t-haplotype, a mouse meiotic driver, highlights its complex history and specialized biology’, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:79 \">10.15479/AT:ISTA:79 </a>.","apa":"Vicoso, B. (2017). Code for “The genomic characterization of the t-haplotype, a mouse meiotic driver, highlights its complex history and specialized biology.” Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:79 \">https://doi.org/10.15479/AT:ISTA:79 </a>","chicago":"Vicoso, Beatriz. “Code for ‘The Genomic Characterization of the t-Haplotype, a Mouse Meiotic Driver, Highlights Its Complex History and Specialized Biology.’” Institute of Science and Technology Austria, 2017. <a href=\"https://doi.org/10.15479/AT:ISTA:79 \">https://doi.org/10.15479/AT:ISTA:79 </a>."},"oa":1},{"article_number":"0632","department":[{"_id":"SyCr"}],"isi":1,"doi":"10.1098/rsbl.2017.0632","publication_identifier":{"issn":["1744-9561"]},"external_id":{"isi":["000418695400010"],"pmid":["29237813"]},"language":[{"iso":"eng"}],"scopus_import":"1","oa_version":"None","month":"12","author":[{"full_name":"Futo, Momir","last_name":"Futo","first_name":"Momir"},{"full_name":"Sell, Marie","last_name":"Sell","first_name":"Marie"},{"first_name":"Megan","orcid":"0000-0002-8696-6978","id":"29D0B332-F248-11E8-B48F-1D18A9856A87","full_name":"Kutzer, Megan","last_name":"Kutzer"},{"first_name":"Joachim","full_name":"Kurtz, Joachim","last_name":"Kurtz"}],"date_published":"2017-12-01T00:00:00Z","date_updated":"2025-09-11T08:07:58Z","publist_id":"7255","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"Specificity of oral immune priming in the red flour beetle Tribolium castaneum","article_type":"original","quality_controlled":"1","year":"2017","date_created":"2018-12-11T11:47:10Z","citation":{"ama":"Futo M, Sell M, Kutzer M, Kurtz J. Specificity of oral immune priming in the red flour beetle Tribolium castaneum. <i>Biology Letters</i>. 2017;13(12). doi:<a href=\"https://doi.org/10.1098/rsbl.2017.0632\">10.1098/rsbl.2017.0632</a>","ista":"Futo M, Sell M, Kutzer M, Kurtz J. 2017. Specificity of oral immune priming in the red flour beetle Tribolium castaneum. Biology Letters. 13(12), 0632.","apa":"Futo, M., Sell, M., Kutzer, M., &#38; Kurtz, J. (2017). Specificity of oral immune priming in the red flour beetle Tribolium castaneum. <i>Biology Letters</i>. The Royal Society. <a href=\"https://doi.org/10.1098/rsbl.2017.0632\">https://doi.org/10.1098/rsbl.2017.0632</a>","chicago":"Futo, Momir, Marie Sell, Megan Kutzer, and Joachim Kurtz. “Specificity of Oral Immune Priming in the Red Flour Beetle Tribolium Castaneum.” <i>Biology Letters</i>. The Royal Society, 2017. <a href=\"https://doi.org/10.1098/rsbl.2017.0632\">https://doi.org/10.1098/rsbl.2017.0632</a>.","ieee":"M. Futo, M. Sell, M. Kutzer, and J. Kurtz, “Specificity of oral immune priming in the red flour beetle Tribolium castaneum,” <i>Biology Letters</i>, vol. 13, no. 12. The Royal Society, 2017.","short":"M. Futo, M. Sell, M. Kutzer, J. Kurtz, Biology Letters 13 (2017).","mla":"Futo, Momir, et al. “Specificity of Oral Immune Priming in the Red Flour Beetle Tribolium Castaneum.” <i>Biology Letters</i>, vol. 13, no. 12, 0632, The Royal Society, 2017, doi:<a href=\"https://doi.org/10.1098/rsbl.2017.0632\">10.1098/rsbl.2017.0632</a>."},"article_processing_charge":"No","publisher":"The Royal Society","issue":"12","publication":"Biology Letters","day":"01","volume":13,"type":"journal_article","publication_status":"published","status":"public","pmid":1,"_id":"558","abstract":[{"lang":"eng","text":"Immune specificity is the degree to which a host’s immune system discriminates among various pathogens or antigenic variants. Vertebrate immune memory is highly specific due to antibody responses. On the other hand, some invertebrates show immune priming, i.e. improved survival after secondary exposure to a previously encountered pathogen. Until now, specificity of priming has only been demonstrated via the septic infection route or when live pathogens were used for priming. Therefore, we tested for specificity in the oral priming route in the red flour beetle, Tribolium castaneum. For priming, we used pathogen-free supernatants derived from three different strains of the entomopathogen, Bacillus thuringiensis, which express different Cry toxin variants known for their toxicity against this beetle. Subsequent exposure to the infective spores showed that oral priming was specific for two naturally occurring strains, while a third engineered strain did not induce any priming effect. Our data demonstrate that oral immune priming with a non-infectious bacterial agent can be specific, but the priming effect is not universal across all bacterial strains."}],"intvolume":"        13"},{"publication_status":"published","arxiv":1,"main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1702.03229"}],"status":"public","_id":"560","abstract":[{"lang":"eng","text":"In a recent article (Jentzen et al. 2016 Commun. Math. Sci. 14, 1477–1500 (doi:10.4310/CMS.2016.v14. n6.a1)), it has been established that, for every arbitrarily slow convergence speed and every natural number d ? {4, 5, . . .}, there exist d-dimensional stochastic differential equations with infinitely often differentiable and globally bounded coefficients such that no approximation method based on finitely many observations of the driving Brownian motion can converge in absolute mean to the solution faster than the given speed of convergence. In this paper, we strengthen the above result by proving that this slow convergence phenomenon also arises in two (d = 2) and three (d = 3) space dimensions."}],"intvolume":"       473","article_processing_charge":"No","publisher":"Royal Society of London","publication":"Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences","issue":"2207","day":"01","volume":473,"type":"journal_article","quality_controlled":"1","year":"2017","date_created":"2018-12-11T11:47:11Z","citation":{"ieee":"M. Gerencser, A. Jentzen, and D. Salimova, “On stochastic differential equations with arbitrarily slow convergence rates for strong approximation in two space dimensions,” <i>Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences</i>, vol. 473, no. 2207. Royal Society of London, 2017.","mla":"Gerencser, Mate, et al. “On Stochastic Differential Equations with Arbitrarily Slow Convergence Rates for Strong Approximation in Two Space Dimensions.” <i>Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences</i>, vol. 473, no. 2207, 0104, Royal Society of London, 2017, doi:<a href=\"https://doi.org/10.1098/rspa.2017.0104\">10.1098/rspa.2017.0104</a>.","short":"M. Gerencser, A. Jentzen, D. Salimova, Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences 473 (2017).","ista":"Gerencser M, Jentzen A, Salimova D. 2017. On stochastic differential equations with arbitrarily slow convergence rates for strong approximation in two space dimensions. Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences. 473(2207), 0104.","ama":"Gerencser M, Jentzen A, Salimova D. On stochastic differential equations with arbitrarily slow convergence rates for strong approximation in two space dimensions. <i>Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences</i>. 2017;473(2207). doi:<a href=\"https://doi.org/10.1098/rspa.2017.0104\">10.1098/rspa.2017.0104</a>","chicago":"Gerencser, Mate, Arnulf Jentzen, and Diyora Salimova. “On Stochastic Differential Equations with Arbitrarily Slow Convergence Rates for Strong Approximation in Two Space Dimensions.” <i>Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences</i>. Royal Society of London, 2017. <a href=\"https://doi.org/10.1098/rspa.2017.0104\">https://doi.org/10.1098/rspa.2017.0104</a>.","apa":"Gerencser, M., Jentzen, A., &#38; Salimova, D. (2017). On stochastic differential equations with arbitrarily slow convergence rates for strong approximation in two space dimensions. <i>Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences</i>. Royal Society of London. <a href=\"https://doi.org/10.1098/rspa.2017.0104\">https://doi.org/10.1098/rspa.2017.0104</a>"},"oa":1,"publist_id":"7256","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"On stochastic differential equations with arbitrarily slow convergence rates for strong approximation in two space dimensions","ec_funded":1,"author":[{"last_name":"Gerencser","id":"44ECEDF2-F248-11E8-B48F-1D18A9856A87","full_name":"Gerencser, Mate","first_name":"Mate"},{"full_name":"Jentzen, Arnulf","last_name":"Jentzen","first_name":"Arnulf"},{"last_name":"Salimova","full_name":"Salimova, Diyora","first_name":"Diyora"}],"date_published":"2017-11-01T00:00:00Z","date_updated":"2025-09-18T07:33:24Z","project":[{"call_identifier":"FP7","_id":"25681D80-B435-11E9-9278-68D0E5697425","name":"International IST Postdoc Fellowship Programme","grant_number":"291734"}],"external_id":{"isi":["000416736700003"],"arxiv":["1702.03229"]},"language":[{"iso":"eng"}],"scopus_import":"1","oa_version":"Submitted Version","month":"11","doi":"10.1098/rspa.2017.0104","publication_identifier":{"issn":["1364-5021"]},"article_number":"0104","isi":1,"department":[{"_id":"JaMa"}]},{"publisher":"American Mathematical Society","article_processing_charge":"No","series_title":"Courant Lecture Notes","type":"book","volume":28,"day":"01","page":"226","publication_status":"published","intvolume":"        28","_id":"567","abstract":[{"text":"This book is a concise and self-contained introduction of recent techniques to prove local spectral universality for large random matrices. Random matrix theory is a fast expanding research area, and this book mainly focuses on the methods that the authors participated in developing over the past few years. Many other interesting topics are not included, and neither are several new developments within the framework of these methods. The authors have chosen instead to present key concepts that they believe are the core of these methods and should be relevant for future applications. They keep technicalities to a minimum to make the book accessible to graduate students. With this in mind, they include in this book the basic notions and tools for high-dimensional analysis, such as large deviation, entropy, Dirichlet form, and the logarithmic Sobolev inequality.\r\n","lang":"eng"}],"status":"public","publist_id":"7247","title":"A Dynamical Approach to Random Matrix Theory","ec_funded":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2018-12-11T11:47:13Z","year":"2017","quality_controlled":"1","corr_author":"1","citation":{"ama":"Erdös L, Yau H. <i>A Dynamical Approach to Random Matrix Theory</i>. Vol 28. American Mathematical Society; 2017. doi:<a href=\"https://doi.org/10.1090/cln/028\">10.1090/cln/028</a>","ista":"Erdös L, Yau H. 2017. A Dynamical Approach to Random Matrix Theory, American Mathematical Society, 226p.","apa":"Erdös, L., &#38; Yau, H. (2017). <i>A Dynamical Approach to Random Matrix Theory</i> (Vol. 28). American Mathematical Society. <a href=\"https://doi.org/10.1090/cln/028\">https://doi.org/10.1090/cln/028</a>","chicago":"Erdös, László, and Horng Yau. <i>A Dynamical Approach to Random Matrix Theory</i>. Vol. 28. Courant Lecture Notes. American Mathematical Society, 2017. <a href=\"https://doi.org/10.1090/cln/028\">https://doi.org/10.1090/cln/028</a>.","short":"L. Erdös, H. Yau, A Dynamical Approach to Random Matrix Theory, American Mathematical Society, 2017.","mla":"Erdös, László, and Horng Yau. <i>A Dynamical Approach to Random Matrix Theory</i>. Vol. 28, American Mathematical Society, 2017, doi:<a href=\"https://doi.org/10.1090/cln/028\">10.1090/cln/028</a>.","ieee":"L. Erdös and H. Yau, <i>A Dynamical Approach to Random Matrix Theory</i>, vol. 28. American Mathematical Society, 2017."},"language":[{"iso":"eng"}],"month":"01","oa_version":"None","date_published":"2017-01-01T00:00:00Z","alternative_title":["Courant Lecture Notes"],"author":[{"full_name":"Erdös, László","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","last_name":"Erdös","orcid":"0000-0001-5366-9603","first_name":"László"},{"first_name":"Horng","full_name":"Yau, Horng","last_name":"Yau"}],"date_updated":"2025-04-15T08:05:02Z","project":[{"grant_number":"338804","call_identifier":"FP7","_id":"258DCDE6-B435-11E9-9278-68D0E5697425","name":"Random matrices, universality and disordered quantum systems"}],"department":[{"_id":"LaEr"}],"doi":"10.1090/cln/028","publication_identifier":{"isbn":["9-781-4704-3648-3"],"eisbn":["978-1-4704-4194-4"]}},{"doi":"10.4310/HHA.2017.v19.n2.a16","publication_identifier":{"issn":["1532-0073"]},"department":[{"_id":"UlWa"},{"_id":"HeEd"}],"isi":1,"date_published":"2017-01-01T00:00:00Z","author":[{"orcid":"0000-0001-8878-8397","first_name":"Peter","last_name":"Franek","full_name":"Franek, Peter","id":"473294AE-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Krcál","id":"33E21118-F248-11E8-B48F-1D18A9856A87","full_name":"Krcál, Marek","first_name":"Marek"}],"project":[{"grant_number":"291734","call_identifier":"FP7","_id":"25681D80-B435-11E9-9278-68D0E5697425","name":"International IST Postdoc Fellowship Programme"},{"grant_number":"701309","name":"Atomic Resolution Structures of Mitochondrial Respiratory Chain Supercomplexes","_id":"2590DB08-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"}],"date_updated":"2025-09-11T07:41:51Z","language":[{"iso":"eng"}],"external_id":{"arxiv":["1507.04310"],"isi":["000440749400010"]},"month":"01","scopus_import":"1","oa_version":"Submitted Version","date_created":"2018-12-11T11:47:14Z","year":"2017","corr_author":"1","quality_controlled":"1","oa":1,"citation":{"apa":"Franek, P., &#38; Krcál, M. (2017). Persistence of zero sets. <i>Homology, Homotopy and Applications</i>. International Press. <a href=\"https://doi.org/10.4310/HHA.2017.v19.n2.a16\">https://doi.org/10.4310/HHA.2017.v19.n2.a16</a>","chicago":"Franek, Peter, and Marek Krcál. “Persistence of Zero Sets.” <i>Homology, Homotopy and Applications</i>. International Press, 2017. <a href=\"https://doi.org/10.4310/HHA.2017.v19.n2.a16\">https://doi.org/10.4310/HHA.2017.v19.n2.a16</a>.","ama":"Franek P, Krcál M. Persistence of zero sets. <i>Homology, Homotopy and Applications</i>. 2017;19(2):313-342. doi:<a href=\"https://doi.org/10.4310/HHA.2017.v19.n2.a16\">10.4310/HHA.2017.v19.n2.a16</a>","ista":"Franek P, Krcál M. 2017. Persistence of zero sets. Homology, Homotopy and Applications. 19(2), 313–342.","short":"P. Franek, M. Krcál, Homology, Homotopy and Applications 19 (2017) 313–342.","mla":"Franek, Peter, and Marek Krcál. “Persistence of Zero Sets.” <i>Homology, Homotopy and Applications</i>, vol. 19, no. 2, International Press, 2017, pp. 313–42, doi:<a href=\"https://doi.org/10.4310/HHA.2017.v19.n2.a16\">10.4310/HHA.2017.v19.n2.a16</a>.","ieee":"P. Franek and M. Krcál, “Persistence of zero sets,” <i>Homology, Homotopy and Applications</i>, vol. 19, no. 2. International Press, pp. 313–342, 2017."},"publist_id":"7246","title":"Persistence of zero sets","ec_funded":1,"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","arxiv":1,"publication_status":"published","abstract":[{"text":"We study robust properties of zero sets of continuous maps f: X → ℝn. Formally, we analyze the family Z&lt; r(f) := (g-1(0): ||g - f|| &lt; r) of all zero sets of all continuous maps g closer to f than r in the max-norm. All of these sets are outside A := (x: |f(x)| ≥ r) and we claim that Z&lt; r(f) is fully determined by A and an element of a certain cohomotopy group which (by a recent result) is computable whenever the dimension of X is at most 2n - 3. By considering all r &gt; 0 simultaneously, the pointed cohomotopy groups form a persistence module-a structure leading to persistence diagrams as in the case of persistent homology or well groups. Eventually, we get a descriptor of persistent robust properties of zero sets that has better descriptive power (Theorem A) and better computability status (Theorem B) than the established well diagrams. Moreover, if we endow every point of each zero set with gradients of the perturbation, the robust description of the zero sets by elements of cohomotopy groups is in some sense the best possible (Theorem C).","lang":"eng"}],"_id":"568","intvolume":"        19","status":"public","main_file_link":[{"url":"https://arxiv.org/abs/1507.04310","open_access":"1"}],"issue":"2","publication":"Homology, Homotopy and Applications","publisher":"International Press","article_processing_charge":"No","type":"journal_article","volume":19,"day":"01","page":"313 - 342"},{"citation":{"ista":"Spira F, Cuylen Haering S, Mehta S, Samwer M, Reversat A, Verma A, Oldenbourg R, Sixt MK, Gerlich D. 2017. Cytokinesis in vertebrate cells initiates by contraction of an equatorial actomyosin network composed of randomly oriented filaments. eLife. 6, e30867.","ama":"Spira F, Cuylen Haering S, Mehta S, et al. Cytokinesis in vertebrate cells initiates by contraction of an equatorial actomyosin network composed of randomly oriented filaments. <i>eLife</i>. 2017;6. doi:<a href=\"https://doi.org/10.7554/eLife.30867\">10.7554/eLife.30867</a>","chicago":"Spira, Felix, Sara Cuylen Haering, Shalin Mehta, Matthias Samwer, Anne Reversat, Amitabh Verma, Rudolf Oldenbourg, Michael K Sixt, and Daniel Gerlich. “Cytokinesis in Vertebrate Cells Initiates by Contraction of an Equatorial Actomyosin Network Composed of Randomly Oriented Filaments.” <i>ELife</i>. eLife Sciences Publications, 2017. <a href=\"https://doi.org/10.7554/eLife.30867\">https://doi.org/10.7554/eLife.30867</a>.","apa":"Spira, F., Cuylen Haering, S., Mehta, S., Samwer, M., Reversat, A., Verma, A., … Gerlich, D. (2017). Cytokinesis in vertebrate cells initiates by contraction of an equatorial actomyosin network composed of randomly oriented filaments. <i>ELife</i>. eLife Sciences Publications. <a href=\"https://doi.org/10.7554/eLife.30867\">https://doi.org/10.7554/eLife.30867</a>","ieee":"F. Spira <i>et al.</i>, “Cytokinesis in vertebrate cells initiates by contraction of an equatorial actomyosin network composed of randomly oriented filaments,” <i>eLife</i>, vol. 6. eLife Sciences Publications, 2017.","mla":"Spira, Felix, et al. “Cytokinesis in Vertebrate Cells Initiates by Contraction of an Equatorial Actomyosin Network Composed of Randomly Oriented Filaments.” <i>ELife</i>, vol. 6, e30867, eLife Sciences Publications, 2017, doi:<a href=\"https://doi.org/10.7554/eLife.30867\">10.7554/eLife.30867</a>.","short":"F. Spira, S. Cuylen Haering, S. Mehta, M. Samwer, A. Reversat, A. Verma, R. Oldenbourg, M.K. Sixt, D. Gerlich, ELife 6 (2017)."},"oa":1,"quality_controlled":"1","date_created":"2018-12-11T11:47:14Z","year":"2017","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","file_date_updated":"2020-07-14T12:47:10Z","title":"Cytokinesis in vertebrate cells initiates by contraction of an equatorial actomyosin network composed of randomly oriented filaments","publist_id":"7245","pubrep_id":"919","_id":"569","intvolume":"         6","abstract":[{"lang":"eng","text":"The actomyosin ring generates force to ingress the cytokinetic cleavage furrow in animal cells, yet its filament organization and the mechanism of contractility is not well understood. We quantified actin filament order in human cells using fluorescence polarization microscopy and found that cleavage furrow ingression initiates by contraction of an equatorial actin network with randomly oriented filaments. The network subsequently gradually reoriented actin filaments along the cell equator. This strictly depended on myosin II activity, suggesting local network reorganization by mechanical forces. Cortical laser microsurgery revealed that during cytokinesis progression, mechanical tension increased substantially along the direction of the cell equator, while the network contracted laterally along the pole-to-pole axis without a detectable increase in tension. Our data suggest that an asymmetric increase in cortical tension promotes filament reorientation along the cytokinetic cleavage furrow, which might have implications for diverse other biological processes involving actomyosin rings."}],"status":"public","publication_status":"published","file":[{"file_size":9666973,"checksum":"ba09c1451153d39e4f4b7cee013e314c","file_id":"4829","access_level":"open_access","content_type":"application/pdf","relation":"main_file","file_name":"IST-2017-919-v1+1_elife-30867-figures-v1.pdf","date_created":"2018-12-12T10:10:40Z","creator":"system","date_updated":"2020-07-14T12:47:10Z"},{"file_size":5951246,"checksum":"01eb51f1d6ad679947415a51c988e137","access_level":"open_access","file_id":"4830","date_created":"2018-12-12T10:10:41Z","file_name":"IST-2017-919-v1+2_elife-30867-v1.pdf","relation":"main_file","content_type":"application/pdf","date_updated":"2020-07-14T12:47:10Z","creator":"system"}],"volume":6,"day":"06","type":"journal_article","article_processing_charge":"No","publication":"eLife","publisher":"eLife Sciences Publications","license":"https://creativecommons.org/licenses/by/4.0/","publication_identifier":{"issn":["2050-084X"]},"doi":"10.7554/eLife.30867","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"isi":1,"department":[{"_id":"MiSi"}],"article_number":"e30867","date_updated":"2025-09-11T07:41:10Z","author":[{"last_name":"Spira","full_name":"Spira, Felix","first_name":"Felix"},{"last_name":"Cuylen Haering","full_name":"Cuylen Haering, Sara","first_name":"Sara"},{"first_name":"Shalin","last_name":"Mehta","full_name":"Mehta, Shalin"},{"full_name":"Samwer, Matthias","last_name":"Samwer","first_name":"Matthias"},{"id":"35B76592-F248-11E8-B48F-1D18A9856A87","full_name":"Reversat, Anne","last_name":"Reversat","orcid":"0000-0003-0666-8928","first_name":"Anne"},{"full_name":"Verma, Amitabh","last_name":"Verma","first_name":"Amitabh"},{"first_name":"Rudolf","full_name":"Oldenbourg, Rudolf","last_name":"Oldenbourg"},{"first_name":"Michael K","orcid":"0000-0002-6620-9179","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87","full_name":"Sixt, Michael K","last_name":"Sixt"},{"full_name":"Gerlich, Daniel","last_name":"Gerlich","first_name":"Daniel"}],"date_published":"2017-11-06T00:00:00Z","ddc":["570"],"scopus_import":"1","oa_version":"Published Version","has_accepted_license":"1","month":"11","external_id":{"isi":["000414407700001"]},"language":[{"iso":"eng"}]},{"citation":{"ieee":"M. Lagator, S. Sarikas, H. Acar, J. P. Bollback, and C. C. Guet, “Regulatory network structure determines patterns of intermolecular epistasis,” <i>eLife</i>, vol. 6. eLife Sciences Publications, 2017.","mla":"Lagator, Mato, et al. “Regulatory Network Structure Determines Patterns of Intermolecular Epistasis.” <i>ELife</i>, vol. 6, e28921, eLife Sciences Publications, 2017, doi:<a href=\"https://doi.org/10.7554/eLife.28921\">10.7554/eLife.28921</a>.","short":"M. Lagator, S. Sarikas, H. Acar, J.P. Bollback, C.C. Guet, ELife 6 (2017).","ama":"Lagator M, Sarikas S, Acar H, Bollback JP, Guet CC. Regulatory network structure determines patterns of intermolecular epistasis. <i>eLife</i>. 2017;6. doi:<a href=\"https://doi.org/10.7554/eLife.28921\">10.7554/eLife.28921</a>","ista":"Lagator M, Sarikas S, Acar H, Bollback JP, Guet CC. 2017. Regulatory network structure determines patterns of intermolecular epistasis. eLife. 6, e28921.","apa":"Lagator, M., Sarikas, S., Acar, H., Bollback, J. P., &#38; Guet, C. C. (2017). Regulatory network structure determines patterns of intermolecular epistasis. <i>ELife</i>. eLife Sciences Publications. <a href=\"https://doi.org/10.7554/eLife.28921\">https://doi.org/10.7554/eLife.28921</a>","chicago":"Lagator, Mato, Srdjan Sarikas, Hande Acar, Jonathan P Bollback, and Calin C Guet. “Regulatory Network Structure Determines Patterns of Intermolecular Epistasis.” <i>ELife</i>. eLife Sciences Publications, 2017. <a href=\"https://doi.org/10.7554/eLife.28921\">https://doi.org/10.7554/eLife.28921</a>."},"oa":1,"corr_author":"1","quality_controlled":"1","date_created":"2018-12-11T11:47:14Z","year":"2017","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","file_date_updated":"2020-07-14T12:47:10Z","title":"Regulatory network structure determines patterns of intermolecular epistasis","ec_funded":1,"publist_id":"7244","pubrep_id":"918","abstract":[{"lang":"eng","text":"Most phenotypes are determined by molecular systems composed of specifically interacting molecules. However, unlike for individual components, little is known about the distributions of mutational effects of molecular systems as a whole. We ask how the distribution of mutational effects of a transcriptional regulatory system differs from the distributions of its components, by first independently, and then simultaneously, mutating a transcription factor and the associated promoter it represses. We find that the system distribution exhibits increased phenotypic variation compared to individual component distributions - an effect arising from intermolecular epistasis between the transcription factor and its DNA-binding site. In large part, this epistasis can be qualitatively attributed to the structure of the transcriptional regulatory system and could therefore be a common feature in prokaryotes. Counter-intuitively, intermolecular epistasis can alleviate the constraints of individual components, thereby increasing phenotypic variation that selection could act on and facilitating adaptive evolution. "}],"_id":"570","intvolume":"         6","status":"public","publication_status":"published","file":[{"file_size":8453470,"checksum":"273ab17f33305e4eaafd911ff88e7c5b","file_id":"5096","access_level":"open_access","relation":"main_file","content_type":"application/pdf","date_created":"2018-12-12T10:14:42Z","file_name":"IST-2017-918-v1+1_elife-28921-figures-v3.pdf","creator":"system","date_updated":"2020-07-14T12:47:10Z"},{"file_id":"5097","access_level":"open_access","file_size":1953221,"checksum":"b433f90576c7be597cd43367946f8e7f","creator":"system","date_updated":"2020-07-14T12:47:10Z","relation":"main_file","content_type":"application/pdf","file_name":"IST-2017-918-v1+2_elife-28921-v3.pdf","date_created":"2018-12-12T10:14:43Z"}],"volume":6,"day":"13","type":"journal_article","article_processing_charge":"No","publication":"eLife","publisher":"eLife Sciences Publications","publication_identifier":{"issn":["2050-084X"]},"doi":"10.7554/eLife.28921","isi":1,"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"department":[{"_id":"CaGu"},{"_id":"JoBo"},{"_id":"NiBa"}],"article_number":"e28921","date_updated":"2025-09-11T07:40:30Z","project":[{"name":"International IST Postdoc Fellowship Programme","_id":"25681D80-B435-11E9-9278-68D0E5697425","call_identifier":"FP7","grant_number":"291734"},{"grant_number":"648440","_id":"2578D616-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","name":"Selective Barriers to Horizontal Gene Transfer"}],"author":[{"first_name":"Mato","last_name":"Lagator","id":"345D25EC-F248-11E8-B48F-1D18A9856A87","full_name":"Lagator, Mato"},{"first_name":"Srdjan","id":"35F0286E-F248-11E8-B48F-1D18A9856A87","last_name":"Sarikas","full_name":"Sarikas, Srdjan"},{"orcid":"0000-0003-1986-9753","first_name":"Hande","full_name":"Acar, Hande","id":"2DDF136A-F248-11E8-B48F-1D18A9856A87","last_name":"Acar"},{"first_name":"Jonathan P","orcid":"0000-0002-4624-4612","last_name":"Bollback","id":"2C6FA9CC-F248-11E8-B48F-1D18A9856A87","full_name":"Bollback, Jonathan P"},{"first_name":"Calin C","orcid":"0000-0001-6220-2052","last_name":"Guet","full_name":"Guet, Calin C","id":"47F8433E-F248-11E8-B48F-1D18A9856A87"}],"date_published":"2017-11-13T00:00:00Z","ddc":["576"],"scopus_import":"1","oa_version":"Published Version","has_accepted_license":"1","month":"11","external_id":{"isi":["000425868200001"]},"language":[{"iso":"eng"}]},{"language":[{"iso":"eng"}],"external_id":{"isi":["000417362700018"]},"month":"11","scopus_import":"1","oa_version":"None","date_published":"2017-11-30T00:00:00Z","author":[{"last_name":"Gärtner","full_name":"Gärtner, Florian R","id":"397A88EE-F248-11E8-B48F-1D18A9856A87","first_name":"Florian R","orcid":"0000-0001-6120-3723"},{"last_name":"Ahmad","full_name":"Ahmad, Zerkah","first_name":"Zerkah"},{"first_name":"Gerhild","last_name":"Rosenberger","full_name":"Rosenberger, Gerhild"},{"first_name":"Shuxia","full_name":"Fan, Shuxia","last_name":"Fan"},{"first_name":"Leo","last_name":"Nicolai","full_name":"Nicolai, Leo"},{"full_name":"Busch, Benjamin","last_name":"Busch","first_name":"Benjamin"},{"last_name":"Yavuz","full_name":"Yavuz, Gökce","first_name":"Gökce"},{"first_name":"Manja","last_name":"Luckner","full_name":"Luckner, Manja"},{"first_name":"Hellen","full_name":"Ishikawa Ankerhold, Hellen","last_name":"Ishikawa Ankerhold"},{"first_name":"Roman","full_name":"Hennel, Roman","last_name":"Hennel"},{"full_name":"Benechet, Alexandre","last_name":"Benechet","first_name":"Alexandre"},{"first_name":"Michael","full_name":"Lorenz, Michael","last_name":"Lorenz"},{"full_name":"Chandraratne, Sue","last_name":"Chandraratne","first_name":"Sue"},{"last_name":"Schubert","full_name":"Schubert, Irene","first_name":"Irene"},{"first_name":"Sebastian","full_name":"Helmer, Sebastian","last_name":"Helmer"},{"last_name":"Striednig","full_name":"Striednig, Bianca","first_name":"Bianca"},{"first_name":"Konstantin","last_name":"Stark","full_name":"Stark, Konstantin"},{"first_name":"Marek","last_name":"Janko","full_name":"Janko, Marek"},{"full_name":"Böttcher, Ralph","last_name":"Böttcher","first_name":"Ralph"},{"first_name":"Admar","last_name":"Verschoor","full_name":"Verschoor, Admar"},{"last_name":"Leon","full_name":"Leon, Catherine","first_name":"Catherine"},{"last_name":"Gachet","full_name":"Gachet, Christian","first_name":"Christian"},{"last_name":"Gudermann","full_name":"Gudermann, Thomas","first_name":"Thomas"},{"last_name":"Mederos Y Schnitzler","full_name":"Mederos Y Schnitzler, Michael","first_name":"Michael"},{"first_name":"Zachary","last_name":"Pincus","full_name":"Pincus, Zachary"},{"full_name":"Iannacone, Matteo","last_name":"Iannacone","first_name":"Matteo"},{"first_name":"Rainer","last_name":"Haas","full_name":"Haas, Rainer"},{"first_name":"Gerhard","last_name":"Wanner","full_name":"Wanner, Gerhard"},{"first_name":"Kirsten","full_name":"Lauber, Kirsten","last_name":"Lauber"},{"first_name":"Michael K","orcid":"0000-0002-6620-9179","last_name":"Sixt","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87","full_name":"Sixt, Michael K"},{"full_name":"Massberg, Steffen","last_name":"Massberg","first_name":"Steffen"}],"date_updated":"2025-09-11T07:39:45Z","project":[{"call_identifier":"H2020","_id":"260AA4E2-B435-11E9-9278-68D0E5697425","name":"Mechanical Adaptation of Lamellipodial Actin Networks in Migrating Cells","grant_number":"747687"}],"department":[{"_id":"MiSi"}],"isi":1,"doi":"10.1016/j.cell.2017.11.001","publication_identifier":{"issn":["0092-8674"]},"publisher":"Cell Press","publication":"Cell Press","issue":"6","article_processing_charge":"No","type":"journal_article","page":"1368 - 1382","day":"30","volume":171,"publication_status":"published","status":"public","abstract":[{"lang":"eng","text":"Blood platelets are critical for hemostasis and thrombosis and play diverse roles during immune responses. Despite these versatile tasks in mammalian biology, their skills on a cellular level are deemed limited, mainly consisting in rolling, adhesion, and aggregate formation. Here, we identify an unappreciated asset of platelets and show that adherent platelets use adhesion receptors to mechanically probe the adhesive substrate in their local microenvironment. When actomyosin-dependent traction forces overcome substrate resistance, platelets migrate and pile up the adhesive substrate together with any bound particulate material. They use this ability to act as cellular scavengers, scanning the vascular surface for potential invaders and collecting deposited bacteria. Microbe collection by migrating platelets boosts the activity of professional phagocytes, exacerbating inflammatory tissue injury in sepsis. This assigns platelets a central role in innate immune responses and identifies them as potential targets to dampen inflammatory tissue damage in clinical scenarios of severe systemic infection. In addition to their role in thrombosis and hemostasis, platelets can also migrate to sites of infection to help trap bacteria and clear the vascular surface."}],"_id":"571","intvolume":"       171","publist_id":"7243","title":"Migrating platelets are mechano scavengers that collect and bundle bacteria","ec_funded":1,"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","year":"2017","date_created":"2018-12-11T11:47:15Z","quality_controlled":"1","citation":{"apa":"Gärtner, F. R., Ahmad, Z., Rosenberger, G., Fan, S., Nicolai, L., Busch, B., … Massberg, S. (2017). Migrating platelets are mechano scavengers that collect and bundle bacteria. <i>Cell Press</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.cell.2017.11.001\">https://doi.org/10.1016/j.cell.2017.11.001</a>","chicago":"Gärtner, Florian R, Zerkah Ahmad, Gerhild Rosenberger, Shuxia Fan, Leo Nicolai, Benjamin Busch, Gökce Yavuz, et al. “Migrating Platelets Are Mechano Scavengers That Collect and Bundle Bacteria.” <i>Cell Press</i>. Cell Press, 2017. <a href=\"https://doi.org/10.1016/j.cell.2017.11.001\">https://doi.org/10.1016/j.cell.2017.11.001</a>.","ama":"Gärtner FR, Ahmad Z, Rosenberger G, et al. Migrating platelets are mechano scavengers that collect and bundle bacteria. <i>Cell Press</i>. 2017;171(6):1368-1382. doi:<a href=\"https://doi.org/10.1016/j.cell.2017.11.001\">10.1016/j.cell.2017.11.001</a>","ista":"Gärtner FR, Ahmad Z, Rosenberger G, Fan S, Nicolai L, Busch B, Yavuz G, Luckner M, Ishikawa Ankerhold H, Hennel R, Benechet A, Lorenz M, Chandraratne S, Schubert I, Helmer S, Striednig B, Stark K, Janko M, Böttcher R, Verschoor A, Leon C, Gachet C, Gudermann T, Mederos Y Schnitzler M, Pincus Z, Iannacone M, Haas R, Wanner G, Lauber K, Sixt MK, Massberg S. 2017. Migrating platelets are mechano scavengers that collect and bundle bacteria. Cell Press. 171(6), 1368–1382.","short":"F.R. Gärtner, Z. Ahmad, G. Rosenberger, S. Fan, L. Nicolai, B. Busch, G. Yavuz, M. Luckner, H. Ishikawa Ankerhold, R. Hennel, A. Benechet, M. Lorenz, S. Chandraratne, I. Schubert, S. Helmer, B. Striednig, K. Stark, M. Janko, R. Böttcher, A. Verschoor, C. Leon, C. Gachet, T. Gudermann, M. Mederos Y Schnitzler, Z. Pincus, M. Iannacone, R. Haas, G. Wanner, K. Lauber, M.K. Sixt, S. Massberg, Cell Press 171 (2017) 1368–1382.","mla":"Gärtner, Florian R., et al. “Migrating Platelets Are Mechano Scavengers That Collect and Bundle Bacteria.” <i>Cell Press</i>, vol. 171, no. 6, Cell Press, 2017, pp. 1368–82, doi:<a href=\"https://doi.org/10.1016/j.cell.2017.11.001\">10.1016/j.cell.2017.11.001</a>.","ieee":"F. R. Gärtner <i>et al.</i>, “Migrating platelets are mechano scavengers that collect and bundle bacteria,” <i>Cell Press</i>, vol. 171, no. 6. Cell Press, pp. 1368–1382, 2017."}},{"quality_controlled":"1","corr_author":"1","date_created":"2018-12-11T11:47:15Z","year":"2017","citation":{"chicago":"Olatunji, Damilola, Danny Geelen, and Inge Verstraeten. “Control of Endogenous Auxin Levels in Plant Root Development.” <i>International Journal of Molecular Sciences</i>. MDPI, 2017. <a href=\"https://doi.org/10.3390/ijms18122587\">https://doi.org/10.3390/ijms18122587</a>.","apa":"Olatunji, D., Geelen, D., &#38; Verstraeten, I. (2017). Control of endogenous auxin levels in plant root development. <i>International Journal of Molecular Sciences</i>. MDPI. <a href=\"https://doi.org/10.3390/ijms18122587\">https://doi.org/10.3390/ijms18122587</a>","ista":"Olatunji D, Geelen D, Verstraeten I. 2017. Control of endogenous auxin levels in plant root development. International Journal of Molecular Sciences. 18(12), 2587.","ama":"Olatunji D, Geelen D, Verstraeten I. Control of endogenous auxin levels in plant root development. <i>International Journal of Molecular Sciences</i>. 2017;18(12). doi:<a href=\"https://doi.org/10.3390/ijms18122587\">10.3390/ijms18122587</a>","mla":"Olatunji, Damilola, et al. “Control of Endogenous Auxin Levels in Plant Root Development.” <i>International Journal of Molecular Sciences</i>, vol. 18, no. 12, 2587, MDPI, 2017, doi:<a href=\"https://doi.org/10.3390/ijms18122587\">10.3390/ijms18122587</a>.","ieee":"D. Olatunji, D. Geelen, and I. Verstraeten, “Control of endogenous auxin levels in plant root development,” <i>International Journal of Molecular Sciences</i>, vol. 18, no. 12. MDPI, 2017.","short":"D. Olatunji, D. Geelen, I. Verstraeten, International Journal of Molecular Sciences 18 (2017)."},"oa":1,"publist_id":"7242","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","file_date_updated":"2020-07-14T12:47:10Z","title":"Control of endogenous auxin levels in plant root development","publication_status":"published","file":[{"access_level":"open_access","file_id":"4718","file_size":920962,"checksum":"82d51f11e493f7eec02976d9a9a9805e","date_updated":"2020-07-14T12:47:10Z","creator":"system","file_name":"IST-2017-917-v1+1_ijms-18-02587.pdf","date_created":"2018-12-12T10:08:55Z","content_type":"application/pdf","relation":"main_file"}],"pubrep_id":"917","_id":"572","abstract":[{"text":"In this review, we summarize the different biosynthesis-related pathways that contribute to the regulation of endogenous auxin in plants. We demonstrate that all known genes involved in auxin biosynthesis also have a role in root formation, from the initiation of a root meristem during embryogenesis to the generation of a functional root system with a primary root, secondary lateral root branches and adventitious roots. Furthermore, the versatile adaptation of root development in response to environmental challenges is mediated by both local and distant control of auxin biosynthesis. In conclusion, auxin homeostasis mediated by spatial and temporal regulation of auxin biosynthesis plays a central role in determining root architecture.","lang":"eng"}],"intvolume":"        18","status":"public","article_processing_charge":"No","publication":"International Journal of Molecular Sciences","issue":"12","publisher":"MDPI","volume":18,"day":"01","type":"journal_article","doi":"10.3390/ijms18122587","article_number":"2587","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"isi":1,"department":[{"_id":"JiFr"}],"author":[{"first_name":"Damilola","full_name":"Olatunji, Damilola","last_name":"Olatunji"},{"first_name":"Danny","last_name":"Geelen","full_name":"Geelen, Danny"},{"orcid":"0000-0001-7241-2328","first_name":"Inge","id":"362BF7FE-F248-11E8-B48F-1D18A9856A87","last_name":"Verstraeten","full_name":"Verstraeten, Inge"}],"date_published":"2017-12-01T00:00:00Z","ddc":["580"],"date_updated":"2025-09-11T07:38:50Z","external_id":{"isi":["000418896700091"]},"language":[{"iso":"eng"}],"oa_version":"Published Version","scopus_import":"1","has_accepted_license":"1","month":"12"}]