[{"department":[{"_id":"PreCl"}],"file_date_updated":"2026-10-19T08:25:17Z","publication_status":"published","OA_type":"hybrid","language":[{"iso":"eng"}],"day":"01","title":"How we care about laboratory animals: Acknowledging differences towards a more comprehensive concept of caring","citation":{"ieee":"S. Schober, A. Vitale, and B. Riso, “How we care about laboratory animals: Acknowledging differences towards a more comprehensive concept of caring,” <i>Journal of Applied Animal Ethics Research</i>, vol. 8, no. 1. Brill Academic Publishers, pp. 88–104, 2026.","short":"S. Schober, A. Vitale, B. Riso, Journal of Applied Animal Ethics Research 8 (2026) 88–104.","apa":"Schober, S., Vitale, A., &#38; Riso, B. (2026). How we care about laboratory animals: Acknowledging differences towards a more comprehensive concept of caring. <i>Journal of Applied Animal Ethics Research</i>. Brill Academic Publishers. <a href=\"https://doi.org/10.1163/25889567-bja10078\">https://doi.org/10.1163/25889567-bja10078</a>","chicago":"Schober, Sophie, Augusto Vitale, and Brigida Riso. “How We Care about Laboratory Animals: Acknowledging Differences towards a More Comprehensive Concept of Caring.” <i>Journal of Applied Animal Ethics Research</i>. Brill Academic Publishers, 2026. <a href=\"https://doi.org/10.1163/25889567-bja10078\">https://doi.org/10.1163/25889567-bja10078</a>.","ama":"Schober S, Vitale A, Riso B. How we care about laboratory animals: Acknowledging differences towards a more comprehensive concept of caring. <i>Journal of Applied Animal Ethics Research</i>. 2026;8(1):88-104. doi:<a href=\"https://doi.org/10.1163/25889567-bja10078\">10.1163/25889567-bja10078</a>","mla":"Schober, Sophie, et al. “How We Care about Laboratory Animals: Acknowledging Differences towards a More Comprehensive Concept of Caring.” <i>Journal of Applied Animal Ethics Research</i>, vol. 8, no. 1, Brill Academic Publishers, 2026, pp. 88–104, doi:<a href=\"https://doi.org/10.1163/25889567-bja10078\">10.1163/25889567-bja10078</a>.","ista":"Schober S, Vitale A, Riso B. 2026. How we care about laboratory animals: Acknowledging differences towards a more comprehensive concept of caring. Journal of Applied Animal Ethics Research. 8(1), 88–104."},"month":"09","researchdata_availability":"no","date_published":"2026-09-01T00:00:00Z","abstract":[{"text":"The concept of Culture of Care fosters a research environment where lab animals and humans are cared for and respected. Several aspects, such as perception of suffering, time, perceived value of an animal, potential benefits of the research, and public opinion, might influence care for animals. The European Directive 2010/63/EU on the protection of animals used for scientific purposes has represented an advance in animal welfare standards and care. However, the question of how we care about animals in practice, and of why this debate is important to reflect on still exist. Therefore, we draw upon the case study of laboratory non-human primates, to illustrate how these tensions go from theory to practice. It illustrates the conflicts and emotions, by exposing the limitations of the standards and norms in the field. Debating care requires a more comprehensive notion of care, one that goes beyond normative decisions to enable care in practice.","lang":"eng"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2026","fulldoi":"https://doi.org/10.1163/25889567-bja10078","ddc":["570"],"oa_version":"Published Version","_id":"23157","quality_controlled":"1","author":[{"id":"80b0a0ef-4b9f-11ec-b119-8d9d94c4a1d8","last_name":"Schober","first_name":"Sophie","full_name":"Schober, Sophie"},{"full_name":"Vitale, Augusto","first_name":"Augusto","last_name":"Vitale"},{"last_name":"Riso","full_name":"Riso, Brigida","first_name":"Brigida"}],"status":"public","intvolume":"         8","doi":"10.1163/25889567-bja10078","scopus_import":"1","PlanS_conform":"1","article_processing_charge":"Yes (via OA deal)","OA_place":"publisher","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"oa":1,"acknowledgement":"This publication is based upon work from the Ethics Crossover Group within the cost Action improve (“3Rs concepts to improve the quality of biomedical science”), ca21139, supported by cost (European Cooperation in Science and Technology).\r\nWe sincerely thank Nuno Franco for critical reviewing the manuscript.\r\nWe acknowledge support by Open Access Publishing Fund of Karl Landsteiner University, Krems, Austria.","has_accepted_license":"1","publication":"Journal of Applied Animal Ethics Research","das_tickbox":"0","volume":8,"issue":"1","date_created":"2026-10-18T22:01:53Z","publication_identifier":{"eissn":["2588-9567"],"issn":["2588-9559"]},"publisher":"Brill Academic Publishers","type":"journal_article","keyword":["culture of care","culture of care in practice","lab animals","interspecies relationships"],"page":"88-104","date_updated":"2026-10-19T08:28:37Z","supplementarymaterial":"no","article_type":"original","file":[{"content_type":"application/pdf","file_size":464277,"success":1,"access_level":"open_access","relation":"main_file","creator":"dernst","checksum":"a148db5e47af7cbfccaecf8cec0beff6","date_updated":"2026-10-19T08:25:17Z","file_name":"2026_JourAppliedAnimalEthicsResearch_Schober.pdf","file_id":"23168","date_created":"2026-10-19T08:25:17Z"}]},{"scopus_import":"1","article_processing_charge":"No","OA_place":"repository","arxiv":1,"external_id":{"arxiv":["2412.04170"]},"fulldoi":"https://doi.org/10.1007/s00454-025-00790-x","oa_version":"Preprint","doi":"10.1007/s00454-025-00790-x","status":"public","_id":"23158","quality_controlled":"1","author":[{"last_name":"Hollom","full_name":"Hollom, Lawrence","first_name":"Lawrence"},{"id":"9aa8388e-d003-11ee-8458-c4c1d7447977","last_name":"Lichev","first_name":"Lyuben","full_name":"Lichev, Lyuben"},{"last_name":"Mond","full_name":"Mond, Adva","first_name":"Adva"},{"last_name":"Portier","first_name":"Julien","full_name":"Portier, Julien"}],"citation":{"ama":"Hollom L, Lichev L, Mond A, Portier J. A note on high-dimensional discrepancy of subtrees. <i>Discrete and Computational Geometry</i>. 2026. doi:<a href=\"https://doi.org/10.1007/s00454-025-00790-x\">10.1007/s00454-025-00790-x</a>","chicago":"Hollom, Lawrence, Lyuben Lichev, Adva Mond, and Julien Portier. “A Note on High-Dimensional Discrepancy of Subtrees.” <i>Discrete and Computational Geometry</i>. Springer, 2026. <a href=\"https://doi.org/10.1007/s00454-025-00790-x\">https://doi.org/10.1007/s00454-025-00790-x</a>.","short":"L. Hollom, L. Lichev, A. Mond, J. Portier, Discrete and Computational Geometry (2026).","ieee":"L. Hollom, L. Lichev, A. Mond, and J. Portier, “A note on high-dimensional discrepancy of subtrees,” <i>Discrete and Computational Geometry</i>. Springer, 2026.","apa":"Hollom, L., Lichev, L., Mond, A., &#38; Portier, J. (2026). A note on high-dimensional discrepancy of subtrees. <i>Discrete and Computational Geometry</i>. Springer. <a href=\"https://doi.org/10.1007/s00454-025-00790-x\">https://doi.org/10.1007/s00454-025-00790-x</a>","ista":"Hollom L, Lichev L, Mond A, Portier J. 2026. A note on high-dimensional discrepancy of subtrees. Discrete and Computational Geometry.","mla":"Hollom, Lawrence, et al. “A Note on High-Dimensional Discrepancy of Subtrees.” <i>Discrete and Computational Geometry</i>, Springer, 2026, doi:<a href=\"https://doi.org/10.1007/s00454-025-00790-x\">10.1007/s00454-025-00790-x</a>."},"title":"A note on high-dimensional discrepancy of subtrees","month":"10","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2026-10-09T00:00:00Z","abstract":[{"lang":"eng","text":"For a tree T and a function f:E(T)→Sd, the imbalance of a subtree T′⊆T is given by |∑e∈E(T′)f(e)|. The d-dimensional discrepancy of the tree T is the minimum, over all functions f as above, of the maximum imbalance of a subtree of T. We prove tight asymptotic bounds for the discrepancy of a tree T, confirming a conjecture of Krishna, Michaeli, Sarantis, Wang and Wang. We also settle a related conjecture on oriented discrepancy of subtrees by the same authors."}],"researchdata_availability":"no","year":"2026","department":[{"_id":"MaKw"}],"publication_status":"epub_ahead","OA_type":"green","day":"09","language":[{"iso":"eng"}],"project":[{"grant_number":"E624","_id":"e19fef4c-1f3d-11f0-ac04-b8b1af6886d8","name":"THRESHOLDS IN SEMI-RANDOM PROCESSES AND GRAPH EMBEDDINGS"}],"date_updated":"2026-10-19T08:20:42Z","supplementarymaterial":"no","article_type":"original","publication_identifier":{"issn":["0179-5376"],"eissn":["1432-0444"]},"type":"journal_article","publisher":"Springer","keyword":["Trees","High-dimensional discrepancy","Oriented discrepancy"],"das_tickbox":"1","publication":"Discrete and Computational Geometry","acknowledgement":"The authors would like to thank both Béla Bollobás and the anonymous reviewer for their careful readings of the manuscript and for their valuable comments. The first author was funded by Trinity College, Cambridge. The second author was funded in whole or in part by the Austrian Science Fund (FWF) 10.55776/ESP624. The third author was supported by UK Research and Innovation grant MR/W007320/2. The fourth author was funded by EPSRC (Engineering and Physical Sciences Research Council) and by the Cambridge Commonwealth, European and International Trust.","date_created":"2026-10-18T22:01:53Z","mathsc":["05C05","05C35","11K38"],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2412.04170"}],"dataavailabilitystatement":"Data sharing not applicable to this article as no datasets were generated or analysed during the current study.","oa":1},{"publication":"Nature","das_tickbox":"1","acknowledgement":"This work would not have been possible without the technical support in cultivation from K. Hager, F. Baraket, A. Malits and S. Harrer. We thank the Imaging and Optics Facility (IOF) at ISTA for their help in setting up the anaerobic environment during imaging and the Cell Imaging & Ultrastructure Research (CIUS) facility at the University of Vienna for their support. Proteomics analyses were performed by the Mass Spectrometry Facility at Max Perutz Labs using the VBCF instrument pool. We also thank P. Klahn (University of Gothenburg, Sweden), M. Stadler and members of his department (HZI Braunschweig) as well as R. Cox (LUH Hannover) for providing different cytochalasans and P. Bieling (King’s College London) for discussion. Most of this work was funded by the Austrian Science Fund (FWF) with grant DOI 10.55776/Z437 (available at https://doi.org/10.55776/Z437) and further supported by an emerging field grant with grant DOI 10.55776/EFP25 (available at https://doi.org/10.55776/EFP25) to C.S. For open access purposes, the author has applied a CC BY public copyright license to any author accepted manuscript version arising from this submission. This work was further supported by a European Research Council grant ERC-SyG (101071793) to M.S., by the German Research Council through the CytoLabs consortium (Research Unit 5170 to K.R. and T.E.B.S.), by the Japan Society for the Promotion of Science Grant-in-Aid for Scientific Research 22H04985 to H.I. and M.N. Furthermore, R.H. was supported by CZI grant DAF2020-225401 and a grant (https://doi.org/10.37921/120055ratwvi) from the Chan Zuckerberg Initiative DAF. Open access funding provided by University of Vienna.","has_accepted_license":"1","date_created":"2026-10-19T09:26:53Z","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/s41586-026-11063-9"}],"oa":1,"dataavailabilitystatement":"The plots in this manuscript were created using Jupyter Notebook; the source data for all figures have been provided in data source tables. Microscopy raw data for supplementary videos, the Jupyter notebooks to generate the plots and the raw files for the structural phylogenetic analysis are available at https://doi.org/10.6084/m9.figshare.30676367. The remaining raw microscopy data generated for this manuscript are available from https://www.ebi.ac.uk/biostudies/bioimages/studies/S-BIAD3928. The mass spectrometry proteomics data from the Co-IP experiments have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository79 and are available at https://www.ebi.ac.uk/pride/archive/projects/PXD068820. The mass spectrometry proteomics data of the proteome analysis is available at https://www.ebi.ac.uk/pride/archive/projects/PXD074767. Source data are provided with this paper.","supplementarymaterial":"yes","date_updated":"2026-10-19T09:40:50Z","article_type":"original","pmid":1,"publication_identifier":{"issn":["0028-0836"],"eissn":["1476-4687"]},"type":"journal_article","publisher":"Springer Nature","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","researchdata_availability":"yes","date_published":"2026-09-30T00:00:00Z","abstract":[{"lang":"eng","text":"Crawling motility is a hallmark of eukaryotic cells and requires a dynamic actin cytoskeleton, regulated adhesion and spatially organized signalling pathways1,2. Asgard archaea, which are considered the closest known prokaryotic relatives of eukaryotes, potentially encode these functions within their large set of ‘eukaryotic signature proteins’3,4,5,6. The few cultivated members show a complex cell morphology, consisting of a central cell body from which several protrusions extend, filled with an actin-based cytoskeleton7,8. Here, live-cell microscopy of two organisms of the Lokiarchaea and Hodarchaea lineages7,9 showed that they dynamically and greatly change their cell shape on a minute time scale and grow and retract their extensive protrusions with a speed of 1.5–4.8 µm min−1, respectively. After adhering to a glass surface, cells use their protrusions to undergo active crawling motion. In the presence of selected actin inhibitors, however, the observed dynamics were arrested, suggesting a central role of actin in these processes. The observed cellular plasticity and motility are unique features among prokaryotes and might have been crucial for the emergence of the first eukaryotic cells that are thought to have formed through the association of a member of the Asgard archaea and an α-proteobacterium, the ancestor of mitochondria."}],"month":"09","title":"Dynamic protrusions mediate crawling motility in Asgard archaea","citation":{"ama":"Radler P, Viehboeck T, Luo Z-H, et al. Dynamic protrusions mediate crawling motility in Asgard archaea. <i>Nature</i>. 2026. doi:<a href=\"https://doi.org/10.1038/s41586-026-11063-9\">10.1038/s41586-026-11063-9</a>","chicago":"Radler, Philipp, Tobias Viehboeck, Zhen-Hao Luo, Nevena Maslać, Katharina Schmidt, Robert Hauschild, Masaru K. Nobu, et al. “Dynamic Protrusions Mediate Crawling Motility in Asgard Archaea.” <i>Nature</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41586-026-11063-9\">https://doi.org/10.1038/s41586-026-11063-9</a>.","short":"P. Radler, T. Viehboeck, Z.-H. Luo, N. Maslać, K. Schmidt, R. Hauschild, M.K. Nobu, S. Bulgheresi, T.E.B. Stradal, K. Rottner, H. Imachi, M.K. Sixt, C. Schleper, Nature (2026).","ieee":"P. Radler <i>et al.</i>, “Dynamic protrusions mediate crawling motility in Asgard archaea,” <i>Nature</i>. Springer Nature, 2026.","apa":"Radler, P., Viehboeck, T., Luo, Z.-H., Maslać, N., Schmidt, K., Hauschild, R., … Schleper, C. (2026). Dynamic protrusions mediate crawling motility in Asgard archaea. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41586-026-11063-9\">https://doi.org/10.1038/s41586-026-11063-9</a>","ista":"Radler P, Viehboeck T, Luo Z-H, Maslać N, Schmidt K, Hauschild R, Nobu MK, Bulgheresi S, Stradal TEB, Rottner K, Imachi H, Sixt MK, Schleper C. 2026. Dynamic protrusions mediate crawling motility in Asgard archaea. Nature.","mla":"Radler, Philipp, et al. “Dynamic Protrusions Mediate Crawling Motility in Asgard Archaea.” <i>Nature</i>, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41586-026-11063-9\">10.1038/s41586-026-11063-9</a>."},"year":"2026","publication_status":"epub_ahead","acknowledged_ssus":[{"_id":"Bio"}],"department":[{"_id":"MiSi"},{"_id":"Bio"}],"language":[{"iso":"eng"}],"day":"30","project":[{"name":"Pushing from within: Control of cell shape, integrity and motility by cytoskeletal pushing forces","_id":"bd91e723-d553-11ed-ba76-fe7eeb2185fd","grant_number":"101071793"},{"name":"Tools for automation and feedback microscopy","_id":"c08e9ad1-5a5b-11eb-8a69-9d1cf3b07473","grant_number":"CZI01"}],"OA_type":"hybrid","article_processing_charge":"Yes (via OA deal)","OA_place":"publisher","scopus_import":"1","PlanS_conform":"1","external_id":{"pmid":["42816618"]},"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"ddc":["570"],"fulldoi":"https://doi.org/10.1038/s41586-026-11063-9","doi":"10.1038/s41586-026-11063-9","quality_controlled":"1","_id":"23171","author":[{"orcid":"0000-0001-9198-2182 ","id":"40136C2A-F248-11E8-B48F-1D18A9856A87","last_name":"Radler","first_name":"Philipp","full_name":"Radler, Philipp"},{"last_name":"Viehboeck","first_name":"Tobias","full_name":"Viehboeck, Tobias"},{"last_name":"Luo","first_name":"Zhen-Hao","full_name":"Luo, Zhen-Hao"},{"last_name":"Maslać","first_name":"Nevena","full_name":"Maslać, Nevena"},{"last_name":"Schmidt","first_name":"Katharina","full_name":"Schmidt, Katharina"},{"first_name":"Robert","full_name":"Hauschild, Robert","id":"4E01D6B4-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-9843-3522","last_name":"Hauschild"},{"last_name":"Nobu","full_name":"Nobu, Masaru K.","first_name":"Masaru K."},{"last_name":"Bulgheresi","full_name":"Bulgheresi, Silvia","first_name":"Silvia"},{"last_name":"Stradal","full_name":"Stradal, Theresia E. B.","first_name":"Theresia E. B."},{"last_name":"Rottner","full_name":"Rottner, Klemens","first_name":"Klemens"},{"full_name":"Imachi, Hiroyuki","first_name":"Hiroyuki","last_name":"Imachi"},{"last_name":"Sixt","orcid":"0000-0002-6620-9179","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87","full_name":"Sixt, Michael K","first_name":"Michael K"},{"last_name":"Schleper","first_name":"Christa","full_name":"Schleper, Christa"}],"status":"public","oa_version":"Published Version"},{"date_created":"2026-08-02T22:01:54Z","has_accepted_license":"1","publication":"Software Engineering 2026","das_tickbox":"1","alternative_title":["Lecture Notes in Informatics"],"volume":"P-377","dataavailabilitystatement":"All our implementations and data are archived and available at Zenodo5\r\nand are evaluated as an artifact in the ICSE 2025 artifact evaluation. Furthermore, our\r\napproach is integrated into the software verifier Bubaak [CR25] which we submitted as\r\npart of our contribution to SV-COMP 2025.","oa":1,"file":[{"checksum":"3371c63711ed26efa41744834d337d28","creator":"dernst","relation":"main_file","access_level":"open_access","success":1,"content_type":"application/pdf","file_size":147208,"date_created":"2026-10-19T08:39:37Z","file_name":"2026_LNI_Richter.pdf","file_id":"23170","date_updated":"2026-10-19T08:39:37Z"}],"date_updated":"2026-10-19T08:49:32Z","supplementarymaterial":"no","license":"https://creativecommons.org/licenses/by-sa/4.0/","publisher":"Gesellschaft für Informatik","type":"conference","page":"41-42","keyword":["Software Verification","Cooperation","Program Decomposition"],"publication_identifier":{"eissn":["1617-5468"]},"year":"2026","month":"03","title":"Off-the-Shelf cooperative software verification by splitting programs dynamically","citation":{"ama":"Richter C, Chalupa M, Jakobs MC, Wehrheim H. Off-the-Shelf cooperative software verification by splitting programs dynamically. In: <i>Software Engineering 2026</i>. Vol P-377. Gesellschaft für Informatik; 2026:41-42. doi:<a href=\"https://doi.org/10.18420/se2026_45\">10.18420/se2026_45</a>","chicago":"Richter, Cedric, Marek Chalupa, Marie Christine Jakobs, and Heike Wehrheim. “Off-the-Shelf Cooperative Software Verification by Splitting Programs Dynamically.” In <i>Software Engineering 2026</i>, P-377:41–42. Gesellschaft für Informatik, 2026. <a href=\"https://doi.org/10.18420/se2026_45\">https://doi.org/10.18420/se2026_45</a>.","short":"C. Richter, M. Chalupa, M.C. Jakobs, H. Wehrheim, in:, Software Engineering 2026, Gesellschaft für Informatik, 2026, pp. 41–42.","apa":"Richter, C., Chalupa, M., Jakobs, M. C., &#38; Wehrheim, H. (2026). Off-the-Shelf cooperative software verification by splitting programs dynamically. In <i>Software Engineering 2026</i> (Vol. P-377, pp. 41–42). Bonn, Switzerland: Gesellschaft für Informatik. <a href=\"https://doi.org/10.18420/se2026_45\">https://doi.org/10.18420/se2026_45</a>","ieee":"C. Richter, M. Chalupa, M. C. Jakobs, and H. Wehrheim, “Off-the-Shelf cooperative software verification by splitting programs dynamically,” in <i>Software Engineering 2026</i>, Bonn, Switzerland, 2026, vol. P-377, pp. 41–42.","mla":"Richter, Cedric, et al. “Off-the-Shelf Cooperative Software Verification by Splitting Programs Dynamically.” <i>Software Engineering 2026</i>, vol. P-377, Gesellschaft für Informatik, 2026, pp. 41–42, doi:<a href=\"https://doi.org/10.18420/se2026_45\">10.18420/se2026_45</a>.","ista":"Richter C, Chalupa M, Jakobs MC, Wehrheim H. 2026. Off-the-Shelf cooperative software verification by splitting programs dynamically. Software Engineering 2026. SE: Software Engineering, Lecture Notes in Informatics, vol. P-377, 41–42."},"date_published":"2026-03-01T00:00:00Z","researchdata_availability":"yes","abstract":[{"text":"Cooperative software verification aims at improving the effectiveness and efficiency of software verification by enabling multiple verification tools to work together. Existing cooperative verification schemes, however, typically require specialized interfaces or tight integration, limiting their practical applicability. In our International Conference on Software Engineering (ICSE) 2025 publication, we introduce dynamic program splitting – a novel approach that enables cooperation between off-the-shelf verification tools without requiring any modifications. The key idea is to probe verification tools on a given verification task under a time limit and split tasks dynamically that cannot be verified under the given time constraints. The process continues recursively, incrementally identifying program parts that are particularly hard for the given verifier. The remaining unverified parts are provided to a second verifier, allowing to leverage the complementary strengths of different tools. Our evaluation on SV-COMP benchmarks demonstrates that cooperation through dynamic program splitting enables the verification of tasks that none of the individual verifiers can solve on their own.","lang":"eng"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_type":"hybrid","language":[{"iso":"eng"}],"day":"01","file_date_updated":"2026-10-19T08:39:37Z","department":[{"_id":"ToHe"}],"publication_status":"published","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","short":"CC BY-SA (4.0)","image":"/images/cc_by_sa.png","name":"Creative Commons Attribution-ShareAlike 4.0 International Public License (CC BY-SA 4.0)"},"conference":{"end_date":"2026-02-27","location":"Bonn, Switzerland","start_date":"2026-02-23","name":"SE: Software Engineering"},"scopus_import":"1","OA_place":"publisher","article_processing_charge":"No","oa_version":"Published Version","author":[{"full_name":"Richter, Cedric","first_name":"Cedric","last_name":"Richter"},{"full_name":"Chalupa, Marek","first_name":"Marek","last_name":"Chalupa","id":"87e34708-d6c6-11ec-9f5b-9391e7be2463"},{"first_name":"Marie Christine","full_name":"Jakobs, Marie Christine","last_name":"Jakobs"},{"first_name":"Heike","full_name":"Wehrheim, Heike","last_name":"Wehrheim"}],"_id":"22622","status":"public","quality_controlled":"1","doi":"10.18420/se2026_45","fulldoi":"https://doi.org/10.18420/se2026_45","ddc":["000"]},{"acknowledged_ssus":[{"_id":"NMR"},{"_id":"LifeSc"}],"department":[{"_id":"PaSc"},{"_id":"GradSch"}],"publication_status":"epub_ahead","OA_type":"hybrid","language":[{"iso":"eng"}],"day":"13","project":[{"_id":"eb9c82eb-77a9-11ec-83b8-aadd536561cf","name":"AlloSpace. The emergence and mechanisms of allostery","grant_number":"I05812"}],"month":"10","title":"Chemoenzymatic proline isotope labeling for solution and magic-angle spinning protein nuclear magnetic resonance","citation":{"ista":"Rohden D, Napoli F, Lichtenecker RJ, Schanda P. 2026. Chemoenzymatic proline isotope labeling for solution and magic-angle spinning protein nuclear magnetic resonance. ACS Chemical Biology.","mla":"Rohden, Darja, et al. “Chemoenzymatic Proline Isotope Labeling for Solution and Magic-Angle Spinning Protein Nuclear Magnetic Resonance.” <i>ACS Chemical Biology</i>, American Chemical Society, 2026, doi:<a href=\"https://doi.org/10.1021/acschembio.6c00587\">10.1021/acschembio.6c00587</a>.","ama":"Rohden D, Napoli F, Lichtenecker RJ, Schanda P. Chemoenzymatic proline isotope labeling for solution and magic-angle spinning protein nuclear magnetic resonance. <i>ACS Chemical Biology</i>. 2026. doi:<a href=\"https://doi.org/10.1021/acschembio.6c00587\">10.1021/acschembio.6c00587</a>","chicago":"Rohden, Darja, Federico Napoli, Roman J. Lichtenecker, and Paul Schanda. “Chemoenzymatic Proline Isotope Labeling for Solution and Magic-Angle Spinning Protein Nuclear Magnetic Resonance.” <i>ACS Chemical Biology</i>. American Chemical Society, 2026. <a href=\"https://doi.org/10.1021/acschembio.6c00587\">https://doi.org/10.1021/acschembio.6c00587</a>.","short":"D. Rohden, F. Napoli, R.J. Lichtenecker, P. Schanda, ACS Chemical Biology (2026).","apa":"Rohden, D., Napoli, F., Lichtenecker, R. J., &#38; Schanda, P. (2026). Chemoenzymatic proline isotope labeling for solution and magic-angle spinning protein nuclear magnetic resonance. <i>ACS Chemical Biology</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acschembio.6c00587\">https://doi.org/10.1021/acschembio.6c00587</a>","ieee":"D. Rohden, F. Napoli, R. J. Lichtenecker, and P. Schanda, “Chemoenzymatic proline isotope labeling for solution and magic-angle spinning protein nuclear magnetic resonance,” <i>ACS Chemical Biology</i>. American Chemical Society, 2026."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2026-10-13T00:00:00Z","abstract":[{"text":"The prevalence of proline residues in intrinsically disordered proteins, functional hinges of enzymes, and protein interaction sites highlights the importance of studying their local dynamics and interactions at atomic resolution. While nuclear magnetic resonance (NMR) spectroscopy is, in principle, ideally suited for such investigations, the absence of an amide proton precludes the use of conventional 1H–15N amide-detected experiments. 1H–13C-based approaches, though possible, remain challenging in large proteins. In this work, we present a selective labeling strategy that introduces an isolated 1H2δ–13Cδ–15N spin system in proline residues in otherwise deuterated proteins. Our method leverages the enzymatic conversion of ornithine, synthesized from cost-effective isotopic precursors. We demonstrate the utility of this approach by applying it to a 134 kDa enzyme using magic-angle spinning NMR, highlighting its potential to efficiently probe functionally relevant sites in proteins.","lang":"eng"}],"year":"2026","fulldoi":"https://doi.org/10.1021/acschembio.6c00587","ddc":["540"],"corr_author":"1","oa_version":"Published Version","doi":"10.1021/acschembio.6c00587","author":[{"last_name":"Rohden","id":"81dc668a-19fa-11f0-bf31-d56534059ef3","full_name":"Rohden, Darja","first_name":"Darja"},{"id":"d42e08e7-f4fc-11eb-af0a-d71e26138f1b","orcid":"0000-0002-9043-136X","last_name":"Napoli","first_name":"Federico","full_name":"Napoli, Federico"},{"first_name":"Roman J.","full_name":"Lichtenecker, Roman J.","last_name":"Lichtenecker"},{"id":"7B541462-FAF6-11E9-A490-E8DFE5697425","orcid":"0000-0002-9350-7606","last_name":"Schanda","first_name":"Paul","full_name":"Schanda, Paul"}],"_id":"23173","status":"public","quality_controlled":"1","scopus_import":"1","article_processing_charge":"Yes (via OA deal)","OA_place":"publisher","external_id":{"pmid":["42863127"]},"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"main_file_link":[{"url":"https://doi.org/10.1021/acschembio.6c00587","open_access":"1"}],"dataavailabilitystatement":"Supporting Information is available free of charge at https://pubs.acs.org/10.1021/acschembio.6c00587.\r\n\r\nDetailed description of experimental methods; spectra supporting the residue assignment for IiMDH; relaxation analysis of IiMDH proline-Cδ sites; NMR spectra of isolated [13Cδ,15N,2Hβγ4]-Pro (PDF)","oa":1,"publication":"ACS Chemical Biology","das_tickbox":"1","has_accepted_license":"1","acknowledgement":"We thank Undina Guillerm, Rajkumar Singh and Anna Kapitonova for help with protein production. We are grateful to Dominique Madern for discussions and for providing the plasmid of IiMDH. We acknowledge the Scientific Service Units (SSU) of the Institute of Science and Technology Austria (ISTA) through resources provided by the NMR Facility and the Lab Support Facility, as well as the NMR centre and MS centre of the University of Vienna. This work was supported by the Austrian Science Fund (FWF; project number I5812-B) through a French-Austrian binational research project, as well as by the L’Oréal-UNESCO For Women in Science Fellowship, awarded in cooperation with the Austrian Academy of Sciences (ÖAW) and the Austrian Commission for UNESCO.","date_created":"2026-10-19T11:12:28Z","publication_identifier":{"issn":["1554-8929"],"eissn":["1554-8937"]},"pmid":1,"type":"journal_article","publisher":"American Chemical Society","date_updated":"2026-10-19T11:20:33Z","article_type":"original"},{"ddc":["520"],"fulldoi":"https://doi.org/10.1051/0004-6361/202554978","doi":"10.1051/0004-6361/202554978","intvolume":"       708","_id":"23046","author":[{"last_name":"Torres Rodriguez","orcid":"0000-0002-3150-8988","id":"a8df4360-4328-11ee-8f1a-e502d0c83fc2","full_name":"Torres Rodriguez, Santiago","first_name":"Santiago"}],"quality_controlled":"1","status":"public","corr_author":"1","oa_version":"Published Version","DOAJ_listed":"1","OA_place":"publisher","article_processing_charge":"No","arxiv":1,"scopus_import":"1","PlanS_conform":"1","external_id":{"arxiv":["2510.23653"]},"article_number":"A301","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"publication_status":"published","file_date_updated":"2026-10-07T12:22:19Z","department":[{"_id":"LiBu"}],"language":[{"iso":"eng"}],"day":"01","project":[{"name":"IST-BRIDGE: International postdoctoral program","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","call_identifier":"H2020","grant_number":"101034413"}],"OA_type":"diamond","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2026-04-01T00:00:00Z","researchdata_availability":"no","abstract":[{"text":"Most stars form in dense stellar environments, where frequent close encounters can strongly perturb and reshape the early architecture of planetary systems. The Solar System, with its rich population of distant comets, provides a natural laboratory to study these processes. We performed detailed numerical simulations using the LonelyPlanets framework that combines NBODY6++GPU and REBOUND to explore the evolution of debris disks around Solar System analogues embedded in stellar clusters. Two initial configurations are considered, the Extended model and the Compact model, each containing four giant planets and either an extended or compact debris disk. We find that compact disks primarily form Kuiper belt and scattered disk-like populations through planet–disk interactions, while extended disks are more strongly shaped by stellar encounters, producing Oort cloud-like structures and interstellar comets with ejection velocities of 1–3 km s−1. Stellar perturbations are most effective for encounter inclinations between 0° and 30°, giving rise to distinct dynamical populations, like Sednoids, and inner Oort cloud analogues, and a characteristic tail in semimajor axis-eccentricity space. In coplanar encounters, the disk remains largely flattened, whereas polar flybys redistribute angular momentum vertically, producing nearly isotropic outer populations that resemble an emerging Oort cloud. Our results suggest that cometary reservoirs and interstellar objects are natural byproducts of planet–disk interactions and stellar flybys in dense clusters, linking the architecture of outer planetary systems to their birth environments.","lang":"eng"}],"citation":{"ama":"Torres Rodriguez S. Implications for the formation of Oort cloud-like structures and interstellar comets in dense environments. <i>Astronomy &#38; Astrophysics</i>. 2026;708. doi:<a href=\"https://doi.org/10.1051/0004-6361/202554978\">10.1051/0004-6361/202554978</a>","chicago":"Torres Rodriguez, Santiago. “Implications for the Formation of Oort Cloud-like Structures and Interstellar Comets in Dense Environments.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2026. <a href=\"https://doi.org/10.1051/0004-6361/202554978\">https://doi.org/10.1051/0004-6361/202554978</a>.","ieee":"S. Torres Rodriguez, “Implications for the formation of Oort cloud-like structures and interstellar comets in dense environments,” <i>Astronomy &#38; Astrophysics</i>, vol. 708. EDP Sciences, 2026.","apa":"Torres Rodriguez, S. (2026). Implications for the formation of Oort cloud-like structures and interstellar comets in dense environments. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202554978\">https://doi.org/10.1051/0004-6361/202554978</a>","short":"S. Torres Rodriguez, Astronomy &#38; Astrophysics 708 (2026).","ista":"Torres Rodriguez S. 2026. Implications for the formation of Oort cloud-like structures and interstellar comets in dense environments. Astronomy &#38; Astrophysics. 708, A301.","mla":"Torres Rodriguez, Santiago. “Implications for the Formation of Oort Cloud-like Structures and Interstellar Comets in Dense Environments.” <i>Astronomy &#38; Astrophysics</i>, vol. 708, A301, EDP Sciences, 2026, doi:<a href=\"https://doi.org/10.1051/0004-6361/202554978\">10.1051/0004-6361/202554978</a>."},"title":"Implications for the formation of Oort cloud-like structures and interstellar comets in dense environments","month":"04","year":"2026","publication_identifier":{"issn":["0004-6361"],"eissn":["1432-0746"]},"type":"journal_article","publisher":"EDP Sciences","supplementarymaterial":"no","date_updated":"2026-10-20T08:14:04Z","file":[{"content_type":"application/pdf","file_size":9478404,"success":1,"access_level":"open_access","relation":"main_file","creator":"dernst","checksum":"3ea1c5f0fabaa005a4aac7e46f4b6d9c","date_updated":"2026-10-07T12:22:19Z","file_id":"23076","file_name":"2026_AstronomyAstrophysics_Torres.pdf","date_created":"2026-10-07T12:22:19Z"}],"article_type":"original","oa":1,"dataavailabilitystatement":"Movies associated with Figs. 3 and 9 are available at https://www.aanda.org","ec_funded":1,"volume":708,"das_tickbox":"1","publication":"Astronomy & Astrophysics","has_accepted_license":"1","acknowledgement":"We thank the referee for their suggestions and comments,\r\nwhich helped us improve the quality and clarity of the paper. S.T. thanks\r\nYlva Götberg, Maxwell Cai, Diptajyoti Mukherjee, Simon Portegies Zwart, and\r\nAnthony Brown for their valuable feedback and comments. S.T. acknowledges\r\nthe funding from the European Union’s Horizon 2020 research and innovation\r\nprogram under the Marie Skłodowska-Curie grant agreement No 101034413.","date_created":"2026-10-04T22:01:54Z"},{"file":[{"date_created":"2026-07-14T06:45:37Z","file_id":"22331","file_name":"2026_ScienceAdv_Kaufman.pdf","date_updated":"2026-07-14T06:45:37Z","checksum":"461b5f73941fe6b5df2a129c7563601f","relation":"main_file","creator":"dernst","success":1,"access_level":"open_access","content_type":"application/pdf","file_size":8269526}],"article_type":"original","supplementarymaterial":"yes","date_updated":"2026-10-20T08:11:46Z","publisher":"AAAS","type":"journal_article","publication_identifier":{"eissn":["2375-2548"]},"issue":"20","date_created":"2026-07-13T10:52:15Z","volume":12,"acknowledgement":"We thank P. Luzio, N. Bright, and M. S. Robinson for helpful discussions;\r\nJ. Stacey and Y. Fujiharu for technical discussions and assistance; F. Beck for assistance with\r\ncomputing infrastructure; and M. Riggi for discussion of data presentation and figure design.\r\nCryo-E\r\nM data was collected at the Department of Cell and Virus Structure, Max Planck Institute\r\nof Biochemistry. Funding: This work was funded by: the Wellcome Trust, Wellcome Discovery\r\nAward 227915/Z/23/Z (to D.J.O., J.A.G.B., and D.G.S.) and Wellcome PRF 207455/Z/17/Z (to\r\nD.J.O.); the Max Planck Society (to J.A.G.B.); the Medical Research Council (UKRI) MC_\r\nUP_1201/16 (to J.A.G.B.) and MRC DT P MR/N013433/1 (to J.G.G.K.); EMBO Long-term\r\nPostdoctoral Fellowship ALT F-383-\r\n2022\r\n(to G.T.); and the Wellcome Trust/Royal Society, Sir\r\nHenry Dale Fellowship 210481 (to D.C.G) and the Biotechnology and Biological Sciences\r\nResearch Council (UKRI) responsive mode grants BB/W005905/1 and UKRI715 (to D.C.G.).","has_accepted_license":"1","das_tickbox":"1","publication":"Science Advances","oa":1,"dataavailabilitystatement":"Structures determined by electron microscopy are deposited in the Electron\r\nMicroscopy Data Bank under accession codes EMD-54255,\r\nEMD-54256,\r\nEMD-54257,\r\nand\r\nEMD-54258.\r\nCorresponding molecular models are deposited in the Protein Data Bank under\r\naccession codes 9RTW, 9RTX, 9RTY, and 9RTZ. All additional data and code required to\r\nevaluate and reproduce the results in the paper are present in the paper and/or the\r\nsupplementary materials. Any code used is explicitly stated and available in the original\r\npublications. Plasmids and cell lines can be requested by writing to D.C.G. (dg553@ cam. ac. uk)\r\nor D.J.O. (djo30@ cam. ac. uk). All reasonable requests for materials will be honored.","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_number":"eaed1529","article_processing_charge":"Yes","OA_place":"publisher","scopus_import":"1","PlanS_conform":"1","_id":"22306","author":[{"last_name":"Kaufman","first_name":"Jonathan G.G.","full_name":"Kaufman, Jonathan G.G."},{"full_name":"Tagiltsev, Grigory","first_name":"Grigory","last_name":"Tagiltsev"},{"full_name":"Stalder, Danièle S.","first_name":"Danièle S.","last_name":"Stalder"},{"last_name":"Taylor","full_name":"Taylor, Rebecca J.","first_name":"Rebecca J."},{"first_name":"Ioana","full_name":"Sava, Ioana","last_name":"Sava"},{"last_name":"Guo","full_name":"Guo, Hui","first_name":"Hui"},{"last_name":"Ciazynska","first_name":"Katarzyna A.","full_name":"Ciazynska, Katarzyna A."},{"last_name":"Zaccai","full_name":"Zaccai, Nathan R.","first_name":"Nathan R."},{"last_name":"Gray","full_name":"Gray, Sally R.","first_name":"Sally R."},{"id":"05A2795C-31B5-11EA-83A7-7DA23DDC885E","orcid":"0000-0002-5408-5906","last_name":"Vallis","first_name":"Yvonne","full_name":"Vallis, Yvonne"},{"full_name":"Höning, Stefan","first_name":"Stefan","last_name":"Höning"},{"first_name":"Bernard T.","full_name":"Kelly, Bernard T.","last_name":"Kelly"},{"full_name":"Gershlick, David C.","first_name":"David C.","last_name":"Gershlick"},{"full_name":"Briggs, John A.G.","first_name":"John A.G.","last_name":"Briggs"},{"full_name":"Owen, David J.","first_name":"David J.","last_name":"Owen"}],"quality_controlled":"1","status":"public","intvolume":"        12","doi":"10.1126/sciadv.aed1529","oa_version":"Published Version","DOAJ_listed":"1","ddc":["570"],"fulldoi":"https://doi.org/10.1126/sciadv.aed1529","year":"2026","researchdata_availability":"yes","abstract":[{"lang":"eng","text":"The AP3 complex mediates cargo sorting and carrier assembly for the trafficking of transmembrane proteins from endosomes to lysosomes. AP3 is generally believed to localize to clathrin-free, ARF1-positive, elongated carriers in cells, but the architecture of AP3-based coats was unknown. Using in vitro reconstitution and cryo–electron tomography, we demonstrate that AP3:ARF1 spontaneously remodels membranes containing cargo and the phosphoinositide PI(3,5)P\r\n                    <jats:sub>2</jats:sub>\r\n                    into tubular structures coated in spiraling rows of AP3 arches and ARF1 dimers. Targeted point mutations disrupting critical AP3:ARF1 and AP3:AP3 lattice interfaces disrupt AP3 recruitment, carrier formation, and lysosomal cargo trafficking in cells. We propose that AP3 generates tubular carriers on endosomes by organizing ARF1 dimers into elongated membrane-deforming arrays while simultaneously selecting cargo. By demonstrating that AP3:ARF1 can generate carriers without using a clathrin lattice, we explain the clathrin independence of AP3-mediated trafficking."}],"date_published":"2026-05-15T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Architecture of clathrin-independent AP3:ARF1-coated carriers","month":"05","citation":{"ista":"Kaufman JGG, Tagiltsev G, Stalder DS, Taylor RJ, Sava I, Guo H, Ciazynska KA, Zaccai NR, Gray SR, Vallis Y, Höning S, Kelly BT, Gershlick DC, Briggs JAG, Owen DJ. 2026. Architecture of clathrin-independent AP3:ARF1-coated carriers. Science Advances. 12(20), eaed1529.","mla":"Kaufman, Jonathan G. G., et al. “Architecture of Clathrin-Independent AP3:ARF1-Coated Carriers.” <i>Science Advances</i>, vol. 12, no. 20, eaed1529, AAAS, 2026, doi:<a href=\"https://doi.org/10.1126/sciadv.aed1529\">10.1126/sciadv.aed1529</a>.","apa":"Kaufman, J. G. G., Tagiltsev, G., Stalder, D. S., Taylor, R. J., Sava, I., Guo, H., … Owen, D. J. (2026). Architecture of clathrin-independent AP3:ARF1-coated carriers. <i>Science Advances</i>. AAAS. <a href=\"https://doi.org/10.1126/sciadv.aed1529\">https://doi.org/10.1126/sciadv.aed1529</a>","ieee":"J. G. G. Kaufman <i>et al.</i>, “Architecture of clathrin-independent AP3:ARF1-coated carriers,” <i>Science Advances</i>, vol. 12, no. 20. AAAS, 2026.","short":"J.G.G. Kaufman, G. Tagiltsev, D.S. Stalder, R.J. Taylor, I. Sava, H. Guo, K.A. Ciazynska, N.R. Zaccai, S.R. Gray, Y. Vallis, S. Höning, B.T. Kelly, D.C. Gershlick, J.A.G. Briggs, D.J. Owen, Science Advances 12 (2026).","ama":"Kaufman JGG, Tagiltsev G, Stalder DS, et al. Architecture of clathrin-independent AP3:ARF1-coated carriers. <i>Science Advances</i>. 2026;12(20). doi:<a href=\"https://doi.org/10.1126/sciadv.aed1529\">10.1126/sciadv.aed1529</a>","chicago":"Kaufman, Jonathan G.G., Grigory Tagiltsev, Danièle S. Stalder, Rebecca J. Taylor, Ioana Sava, Hui Guo, Katarzyna A. Ciazynska, et al. “Architecture of Clathrin-Independent AP3:ARF1-Coated Carriers.” <i>Science Advances</i>. AAAS, 2026. <a href=\"https://doi.org/10.1126/sciadv.aed1529\">https://doi.org/10.1126/sciadv.aed1529</a>."},"day":"15","language":[{"iso":"eng"}],"OA_type":"gold","publication_status":"published","department":[{"_id":"MaDe"}],"file_date_updated":"2026-07-14T06:45:37Z"},{"citation":{"ista":"Bubis A, Vigliotti L, Serbyn M, Higginbotham AP. 2026. Non-equilibrium plasmon liquid in a Josephson junction chain. Science Advances. 12(7), eady7222.","mla":"Bubis, Anton, et al. “Non-Equilibrium Plasmon Liquid in a Josephson Junction Chain.” <i>Science Advances</i>, vol. 12, no. 7, eady7222, AAAS, 2026, doi:<a href=\"https://doi.org/10.1126/sciadv.ady7222\">10.1126/sciadv.ady7222</a>.","chicago":"Bubis, Anton, Lucia Vigliotti, Maksym Serbyn, and Andrew P Higginbotham. “Non-Equilibrium Plasmon Liquid in a Josephson Junction Chain.” <i>Science Advances</i>. AAAS, 2026. <a href=\"https://doi.org/10.1126/sciadv.ady7222\">https://doi.org/10.1126/sciadv.ady7222</a>.","ama":"Bubis A, Vigliotti L, Serbyn M, Higginbotham AP. Non-equilibrium plasmon liquid in a Josephson junction chain. <i>Science Advances</i>. 2026;12(7). doi:<a href=\"https://doi.org/10.1126/sciadv.ady7222\">10.1126/sciadv.ady7222</a>","short":"A. Bubis, L. Vigliotti, M. Serbyn, A.P. Higginbotham, Science Advances 12 (2026).","ieee":"A. Bubis, L. Vigliotti, M. Serbyn, and A. P. Higginbotham, “Non-equilibrium plasmon liquid in a Josephson junction chain,” <i>Science Advances</i>, vol. 12, no. 7. AAAS, 2026.","apa":"Bubis, A., Vigliotti, L., Serbyn, M., &#38; Higginbotham, A. P. (2026). Non-equilibrium plasmon liquid in a Josephson junction chain. <i>Science Advances</i>. AAAS. <a href=\"https://doi.org/10.1126/sciadv.ady7222\">https://doi.org/10.1126/sciadv.ady7222</a>"},"month":"02","title":"Non-equilibrium plasmon liquid in a Josephson junction chain","abstract":[{"lang":"eng","text":"Equilibrium quantum systems are often described by a gas of weakly interacting normal modes. Bringing such systems far from equilibrium, however, can drastically enhance mode-to-mode interactions. Understanding the resulting liquid is a fundamental question for quantum statistical mechanics and a practical question for engineering driven quantum devices. To tackle this question, we probe the non-equilibrium kinetics of one-dimensional plasmons in a long chain of Josephson junctions. We introduce multimode spectroscopy to controllably study the departure from equilibrium, witnessing the evolution from pairwise coupling between plasma modes at weak driving to dramatic, high-order, cascaded couplings at strong driving. Scaling to many-mode drives, we stimulate interactions between hundreds of modes, resulting in near-continuum internal dynamics. Imaging the resulting non-equilibrium plasmon populations, we then resolve the nonlocal redistribution of energy in the response to a weak perturbation—an explicit verification of the emergence of a strongly interacting, non-equilibrium liquid of plasmons."}],"date_published":"2026-02-13T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2026","file_date_updated":"2026-02-24T07:23:32Z","department":[{"_id":"MaSe"},{"_id":"AnHi"},{"_id":"GeKa"}],"acknowledged_ssus":[{"_id":"NanoFab"},{"_id":"M-Shop"}],"publication_status":"published","OA_type":"gold","language":[{"iso":"eng"}],"day":"13","PlanS_conform":"1","arxiv":1,"article_processing_charge":"Yes","OA_place":"publisher","article_number":"eady7222","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"external_id":{"arxiv":["2504.09721"]},"fulldoi":"https://doi.org/10.1126/sciadv.ady7222","ddc":["530"],"oa_version":"Published Version","DOAJ_listed":"1","corr_author":"1","_id":"21340","quality_controlled":"1","status":"public","author":[{"first_name":"Anton","full_name":"Bubis, Anton","id":"1f6212b5-f795-11ec-9c0c-de4780302890","last_name":"Bubis"},{"first_name":"Lucia","full_name":"Vigliotti, Lucia","id":"539e1e1a-e604-11ee-a1df-f02b018e5c8c","last_name":"Vigliotti"},{"first_name":"Maksym","full_name":"Serbyn, Maksym","orcid":"0000-0002-2399-5827","id":"47809E7E-F248-11E8-B48F-1D18A9856A87","last_name":"Serbyn"},{"first_name":"Andrew P","full_name":"Higginbotham, Andrew P","id":"4AD6785A-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2607-2363","last_name":"Higginbotham"}],"doi":"10.1126/sciadv.ady7222","intvolume":"        12","has_accepted_license":"1","acknowledgement":"We thank V. Vitelli, M. Fruchart, and A. Burshstein for helpful input. We acknowledge technical support from the Nanofabrication Facility and the MIBA machine shop at IST Austria. This research was supported in part by grant NSF PHY-2309135 to the Kavli Institute for Theoretical Physics (KITP), by the Austrian Science Fund (FWF) SFB F86, and by the NOMIS foundation.","publication":"Science Advances","volume":12,"issue":"7","date_created":"2026-02-22T20:47:38Z","oa":1,"date_updated":"2026-10-20T08:10:46Z","article_type":"original","file":[{"date_created":"2026-02-24T07:23:32Z","file_name":"2026_ScienceAdv_Bubis.pdf","file_id":"21353","date_updated":"2026-02-24T07:23:32Z","checksum":"8402f322f8f0e858b1d9aac57e306e31","relation":"main_file","creator":"dernst","success":1,"access_level":"open_access","content_type":"application/pdf","file_size":2775975}],"publication_identifier":{"eissn":["2375-2548"]},"publisher":"AAAS","type":"journal_article"},{"language":[{"iso":"eng"}],"day":"01","OA_type":"gold","publication_status":"published","file_date_updated":"2026-03-02T14:19:35Z","department":[{"_id":"CaHe"}],"year":"2026","date_published":"2026-02-01T00:00:00Z","abstract":[{"lang":"eng","text":"Planarian flatworms are known for their remarkable regenerative capacity; however, the precise intercellular communication mechanisms underlying this process remain unsolved. Here, we report the discovery and characterization of abundant extracellular vesicles (EVs) in planarians. Using imaging and molecular analysis, we show conservation of biogenesis, morphology, and protein composition of planarian EVs. Environmental stressors significantly elevate EV release, indicating that planarians dynamically regulate vesicle production. Functionally, planarian EVs mediate intercellular communication by transferring regulatory signals: We find that they shuttle small RNAs that effect systemic RNA interference (RNAi) throughout the organism. Notably, gene knockdown experiments reveal a crucial role for AGO-3, a member of the Argonaute family of proteins, in modulating the association of small interfering RNAs with EVs, linking the intracellular RNAi machinery to EV-based signaling. These findings highlight EVs as pivotal mediators of cell-cell communication in planarians, with broad implications for understanding the coordination of gene regulation and tissue regeneration in animals."}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Extracellular vesicles mediate stem cell signaling and systemic RNAi in planarians","month":"02","citation":{"ama":"Sasidharan V, Ancellotti L, Doddihal V, et al. Extracellular vesicles mediate stem cell signaling and systemic RNAi in planarians. <i>Science Advances</i>. 2026;12(6). doi:<a href=\"https://doi.org/10.1126/sciadv.ady1461\">10.1126/sciadv.ady1461</a>","chicago":"Sasidharan, Vidyanand, Laura Ancellotti, Viraj Doddihal, Carolyn Brewster, Frederick Mann, Mary Cathleen McKinney, Joseph Varberg, et al. “Extracellular Vesicles Mediate Stem Cell Signaling and Systemic RNAi in Planarians.” <i>Science Advances</i>. AAAS, 2026. <a href=\"https://doi.org/10.1126/sciadv.ady1461\">https://doi.org/10.1126/sciadv.ady1461</a>.","apa":"Sasidharan, V., Ancellotti, L., Doddihal, V., Brewster, C., Mann, F., McKinney, M. C., … Sánchez Alvarado, A. (2026). Extracellular vesicles mediate stem cell signaling and systemic RNAi in planarians. <i>Science Advances</i>. AAAS. <a href=\"https://doi.org/10.1126/sciadv.ady1461\">https://doi.org/10.1126/sciadv.ady1461</a>","short":"V. Sasidharan, L. Ancellotti, V. Doddihal, C. Brewster, F. Mann, M.C. McKinney, J. Varberg, E. Ross, F. Deng, K. Yi, A. Sánchez Alvarado, Science Advances 12 (2026).","ieee":"V. Sasidharan <i>et al.</i>, “Extracellular vesicles mediate stem cell signaling and systemic RNAi in planarians,” <i>Science Advances</i>, vol. 12, no. 6. AAAS, 2026.","mla":"Sasidharan, Vidyanand, et al. “Extracellular Vesicles Mediate Stem Cell Signaling and Systemic RNAi in Planarians.” <i>Science Advances</i>, vol. 12, no. 6, eady1461, AAAS, 2026, doi:<a href=\"https://doi.org/10.1126/sciadv.ady1461\">10.1126/sciadv.ady1461</a>.","ista":"Sasidharan V, Ancellotti L, Doddihal V, Brewster C, Mann F, McKinney MC, Varberg J, Ross E, Deng F, Yi K, Sánchez Alvarado A. 2026. Extracellular vesicles mediate stem cell signaling and systemic RNAi in planarians. Science Advances. 12(6), eady1461."},"_id":"21383","quality_controlled":"1","status":"public","author":[{"first_name":"Vidyanand","full_name":"Sasidharan, Vidyanand","last_name":"Sasidharan"},{"full_name":"Ancellotti, Laura","first_name":"Laura","last_name":"Ancellotti"},{"last_name":"Doddihal","id":"034e0824-174b-11ef-b32b-9366a0e70d1c","full_name":"Doddihal, Viraj","first_name":"Viraj"},{"last_name":"Brewster","full_name":"Brewster, Carolyn","first_name":"Carolyn"},{"full_name":"Mann, Frederick","first_name":"Frederick","last_name":"Mann"},{"last_name":"McKinney","first_name":"Mary Cathleen","full_name":"McKinney, Mary Cathleen"},{"full_name":"Varberg, Joseph","first_name":"Joseph","last_name":"Varberg"},{"last_name":"Ross","first_name":"Eric","full_name":"Ross, Eric"},{"last_name":"Deng","first_name":"Fengyan","full_name":"Deng, Fengyan"},{"first_name":"Kexi","full_name":"Yi, Kexi","last_name":"Yi"},{"first_name":"Alejandro","full_name":"Sánchez Alvarado, Alejandro","last_name":"Sánchez Alvarado"}],"intvolume":"        12","doi":"10.1126/sciadv.ady1461","DOAJ_listed":"1","oa_version":"Published Version","ddc":["570"],"fulldoi":"https://doi.org/10.1126/sciadv.ady1461","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","short":"CC BY-NC (4.0)","image":"/images/cc_by_nc.png","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)"},"article_number":"eady1461","article_processing_charge":"Yes","OA_place":"publisher","scopus_import":"1","oa":1,"issue":"6","date_created":"2026-03-02T10:08:07Z","volume":12,"acknowledgement":"We thank all the Sánchez Alvarado lab members for inputs and discussions. We are grateful to the Stowers Aquatics (particularly the Planarian team), Microscopy, and Molecular Biology core facilities for technical contributions and method development; e. n. lissek and A. Fujii from Oni US and S. Wang from the University of Missouri, Kansas city, for assistance with dStORM imaging; and d. Alburty and A. Page from innovaprep for assisting with the ntA. We also thank M. Miller for the illustrations. This work was supported by the hhMi and Stowers institute. ","has_accepted_license":"1","publication":"Science Advances","publisher":"AAAS","type":"journal_article","publication_identifier":{"eissn":["2375-2548"]},"file":[{"file_name":"2026_ScienceAdv_Sasidharan.pdf","file_id":"21389","date_updated":"2026-03-02T14:19:35Z","date_created":"2026-03-02T14:19:35Z","success":1,"access_level":"open_access","file_size":2841345,"content_type":"application/pdf","checksum":"fa9f6dafe3538e2d2872c098e06d1712","relation":"main_file","creator":"dernst"}],"article_type":"original","license":"https://creativecommons.org/licenses/by-nc/4.0/","date_updated":"2026-10-20T08:11:11Z"},{"oa":1,"date_created":"2026-04-12T22:01:48Z","issue":"13","volume":12,"publication":"Science Advances","acknowledgement":"We thank I. Salecker (Flybow), B. Altenhein (Fas2-Gal4Mz507), A. Nose (UAS-intra- and extra-Fas2::YFP), and C. S. Goodman (UAS-Fas2PEST+/−), as well as the Bloomington Stock Center for providing materials and fly stocks. We thank S. Waddell and the lab, especially B. Senapati, for providing the opportunity to conduct memory experiments at the CNCB, University of Oxford, and for supervision and discussions during this period. We also thank W. Kallina, S. Ilgerl, D. Bartel, A. Grimm, and A. Litin for technical support and the Hummel Lab for stimulating discussions and critical comments on the manuscript. We acknowledge the early exploratory work of A. Mattia, S. Trkulja, C. Schönherr, S. Bogner, B. Simpson, L. Tomasek, H. Roth, H. Vokač, R. Gredler, F. Kapelari, T. Kolarova, C. Ignitsch, Á. Bautista-Soldevila, and M. Kassem.\r\nThis research was funded by the University of Vienna, the Vienna Doctoral School Cognition, Behaviour and Neuroscience (uni:docs fellowship) (to J.W.M.) and by the Austrian Science Fund (FWF) (Cluster of Excellence Neuronal Circuits in Health and Disease, grant DOI 10.55776/COE16; https://www.fwf.ac.at/en/research-radar/10.55776/COE16) (to T.H.). For open access purposes, the author has applied a CC BY public copyright license to any author-accepted manuscript version arising from this submission.","has_accepted_license":"1","type":"journal_article","publisher":"AAAS","publication_identifier":{"eissn":["2375-2548"]},"file":[{"content_type":"application/pdf","file_size":11101140,"success":1,"access_level":"open_access","relation":"main_file","creator":"dernst","checksum":"3eed470fe73e53d2a8d55d6fba6934e3","date_updated":"2026-05-04T09:16:36Z","file_id":"21786","file_name":"2026_ScienceAdv_Markovitsch.pdf","date_created":"2026-05-04T09:16:36Z"}],"article_type":"original","date_updated":"2026-10-20T08:11:29Z","language":[{"iso":"eng"}],"day":"27","OA_type":"gold","publication_status":"published","department":[{"_id":"MiSi"},{"_id":"GradSch"}],"file_date_updated":"2026-05-04T09:16:36Z","year":"2026","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2026-03-27T00:00:00Z","abstract":[{"lang":"eng","text":"Structural and functional differences between brain hemispheres are a common feature of animal nervous systems with reduced bilateral asymmetry often linked to impaired cognitive performance. How neuronal left-right asymmetry is initiated and integrated into a bilaterally symmetrical ground pattern is poorly understood. Here, we show that the directional asymmetry of a Drosophila central brain circuit originates from axonal interactions of two types of bilateral pioneer neurons. Subsequent recruitment of neighboring neurons into the asymmetric neuropil primordium results in hemisphere-specific microcircuits. Circuit lateralization requires dynamic expression of the cell adhesion molecule Fasciclin 2 to maintain structural plasticity in axonal remodeling. Reduced circuit asymmetry following cell type–specific Fasciclin 2 manipulation affects adult brain function. These results reveal an unexpected degree of developmental plasticity of late-born Drosophila neurons in the formation of a circuit node via the lateralized recruitment of symmetric circuit components."}],"month":"03","title":"Sequential formation of Drosophila circuit asymmetry via prolonged structural plasticity","citation":{"ista":"Markovitsch JW, Mitić D, Del Pilar Jiménez García A, Zane A, Kainz S, Kaur R, Hummel T. 2026. Sequential formation of Drosophila circuit asymmetry via prolonged structural plasticity. Science Advances. 12(13), eaea6020.","mla":"Markovitsch, Johann W., et al. “Sequential Formation of Drosophila Circuit Asymmetry via Prolonged Structural Plasticity.” <i>Science Advances</i>, vol. 12, no. 13, eaea6020, AAAS, 2026, doi:<a href=\"https://doi.org/10.1126/sciadv.aea6020\">10.1126/sciadv.aea6020</a>.","chicago":"Markovitsch, Johann W., Daniel Mitić, Alisa Del Pilar Jiménez García, Alsberga Zane, Sarah Kainz, Rashmit Kaur, and Thomas Hummel. “Sequential Formation of Drosophila Circuit Asymmetry via Prolonged Structural Plasticity.” <i>Science Advances</i>. AAAS, 2026. <a href=\"https://doi.org/10.1126/sciadv.aea6020\">https://doi.org/10.1126/sciadv.aea6020</a>.","ama":"Markovitsch JW, Mitić D, Del Pilar Jiménez García A, et al. Sequential formation of Drosophila circuit asymmetry via prolonged structural plasticity. <i>Science Advances</i>. 2026;12(13). doi:<a href=\"https://doi.org/10.1126/sciadv.aea6020\">10.1126/sciadv.aea6020</a>","short":"J.W. Markovitsch, D. Mitić, A. Del Pilar Jiménez García, A. Zane, S. Kainz, R. Kaur, T. Hummel, Science Advances 12 (2026).","ieee":"J. W. Markovitsch <i>et al.</i>, “Sequential formation of Drosophila circuit asymmetry via prolonged structural plasticity,” <i>Science Advances</i>, vol. 12, no. 13. AAAS, 2026.","apa":"Markovitsch, J. W., Mitić, D., Del Pilar Jiménez García, A., Zane, A., Kainz, S., Kaur, R., &#38; Hummel, T. (2026). Sequential formation of Drosophila circuit asymmetry via prolonged structural plasticity. <i>Science Advances</i>. AAAS. <a href=\"https://doi.org/10.1126/sciadv.aea6020\">https://doi.org/10.1126/sciadv.aea6020</a>"},"doi":"10.1126/sciadv.aea6020","intvolume":"        12","quality_controlled":"1","_id":"21707","status":"public","author":[{"last_name":"Markovitsch","full_name":"Markovitsch, Johann W.","first_name":"Johann W."},{"last_name":"Mitić","first_name":"Daniel","full_name":"Mitić, Daniel"},{"last_name":"Del Pilar Jiménez García","first_name":"Alisa","full_name":"Del Pilar Jiménez García, Alisa"},{"last_name":"Zane","orcid":"0009-0003-0415-7603","id":"60f7509a-f652-11ea-9d86-b963d6490d7c","full_name":"Zane, Alsberga","first_name":"Alsberga"},{"full_name":"Kainz, Sarah","first_name":"Sarah","last_name":"Kainz"},{"first_name":"Rashmit","full_name":"Kaur, Rashmit","last_name":"Kaur"},{"full_name":"Hummel, Thomas","first_name":"Thomas","last_name":"Hummel"}],"oa_version":"Published Version","DOAJ_listed":"1","ddc":["570"],"fulldoi":"https://doi.org/10.1126/sciadv.aea6020","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_number":"eaea6020","article_processing_charge":"Yes","OA_place":"publisher","scopus_import":"1"},{"dataavailabilitystatement":"All data are available in the manuscript or the supplementary materials. The raw RNA-seq data have been deposited in the NCBI Gene Expression Omnibus (GEO) under accession number GSE315473. Microbiome sequencing data have been deposited in the Sequence Read Archive (SRA) under BioProject number PRJNA1397137. Materials are available upon request from the corresponding author.","issue":"6807","date_created":"2026-07-13T14:57:10Z","acknowledgement":"We are grateful to H. Guo and L. Liu (Department of Biology, Southern University of Science and Technology) for providing the rgf1/2/3, rgi1/2/3/4, tpst-1, and pepr1/2 lines. We thank K.-h. Liu (College of Life Science, Northwest A&F University) for generously providing the ABA biosensor nlsABACUS2-400n. We also thank J. Li and J. Chang (School of Life Sciences, Lanzhou University) for providing the ahk2-5/cre1-2, ahp1/2/3, arr16/arr17, and pTCSn::GFP lines. Our thanks further extend to D. Qian, also from the School of Life Sciences at Lanzhou University, for sharing Arabidopsis line pTUB6::mCherry-TUB6. We are grateful to Y. Zhao (CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences) for providing nced3/5, snrk2.2/2.3/2.6, and pyl duodecuple mutants. We also acknowledge the Teaching and Research Core Facility at the College of Life Sciences, Northwest A&F University, particularly N. Fan, for their invaluable technical assistance. We also thank Life Science Research Core Services (LSRCS), Northwest A&F University, for helping with characterization, including CLSM (X. Liu). Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China JYB2025XDXM706 (Y.Z.); Qin Chuangyuan High-level Innovation and Entrepreneurship Talent Program QCYRCXM-2022-237 (Y.Z.); Fundamental Research Funds for the Central Universities K20200168 (Y.Z.); National Natural Science Foundation of China 32570375 (Y.Z.); National Natural Science Foundation of China 32400699 (A.Z.); European Research Council (ERC, CYNIPS) 101142681 (J.F.); Austrian Science Fund (FWF): P 37051-B (J.F.).","publication":"Science","das_tickbox":"1","volume":393,"publisher":"AAAS","type":"journal_article","related_material":{"link":[{"url":"https://ista.ac.at/en/news/roots-steer-clear-of-plant-rot/","description":"News on ISTA website","relation":"press_release"}]},"publication_identifier":{"eissn":["1095-9203"],"issn":["0036-8075"]},"pmid":1,"article_type":"original","date_updated":"2026-10-20T08:12:03Z","supplementarymaterial":"yes","OA_type":"closed access","project":[{"name":"Cyclic nucleotides as second messengers in plants","_id":"8f347782-16d5-11f0-9cad-8c19706ee739","grant_number":"101142681"},{"grant_number":"P37051","_id":"7bcece63-9f16-11ee-852c-ae94e099eeb6","name":"Guanylate cyclase activity of TIR1/AFBs auxin receptors"}],"day":"09","language":[{"iso":"eng"}],"department":[{"_id":"JiFr"}],"publication_status":"published","year":"2026","citation":{"ista":"Bao Z, Wang H, Zhang A, Gao R, Gu W, Fan N, Friml J, Zhang Y. 2026. Roots navigate around decay regions by sensing local pH gradients. Science. 393(6807), eadw6568.","mla":"Bao, Zhulatai, et al. “Roots Navigate around Decay Regions by Sensing Local PH Gradients.” <i>Science</i>, vol. 393, no. 6807, eadw6568, AAAS, 2026, doi:<a href=\"https://doi.org/10.1126/science.adw6568\">10.1126/science.adw6568</a>.","chicago":"Bao, Zhulatai, Huihui Wang, Ai Zhang, Ruxi Gao, Wen Gu, Ni Fan, Jiří Friml, and Yuzhou Zhang. “Roots Navigate around Decay Regions by Sensing Local PH Gradients.” <i>Science</i>. AAAS, 2026. <a href=\"https://doi.org/10.1126/science.adw6568\">https://doi.org/10.1126/science.adw6568</a>.","ama":"Bao Z, Wang H, Zhang A, et al. Roots navigate around decay regions by sensing local pH gradients. <i>Science</i>. 2026;393(6807). doi:<a href=\"https://doi.org/10.1126/science.adw6568\">10.1126/science.adw6568</a>","apa":"Bao, Z., Wang, H., Zhang, A., Gao, R., Gu, W., Fan, N., … Zhang, Y. (2026). Roots navigate around decay regions by sensing local pH gradients. <i>Science</i>. AAAS. <a href=\"https://doi.org/10.1126/science.adw6568\">https://doi.org/10.1126/science.adw6568</a>","short":"Z. Bao, H. Wang, A. Zhang, R. Gao, W. Gu, N. Fan, J. Friml, Y. Zhang, Science 393 (2026).","ieee":"Z. Bao <i>et al.</i>, “Roots navigate around decay regions by sensing local pH gradients,” <i>Science</i>, vol. 393, no. 6807. AAAS, 2026."},"month":"07","title":"Roots navigate around decay regions by sensing local pH gradients","abstract":[{"lang":"eng","text":"Plant tropisms enable roots to navigate complex soils by responding to directional environmental cues. Biological decay, although central to nutrient cycling, also creates microbially active and potentially hostile niches. In this work, we identified “saprotropism,” a previously unrecognized growth response that enables roots to actively bend away from decaying plant-derived matter. Fungal-driven microbial decomposition released organic acids and formed stable pH gradients in surrounding soil, allowing roots to pinpoint decay without direct contact. Root epidermal cells sensed this acidic gradient through the root meristem growth factor peptide-receptor module, converting external pH asymmetry into asymmetric abscisic acid (ABA) distribution. ABA asymmetry drove microtubule reorganization, which was decoded into decay-avoidant root bending. Together, these findings establish microbial decay–derived chemical gradients as an instructive signal for root navigation and expand the framework of microbe-soil-plant communication."}],"researchdata_availability":"yes","date_published":"2026-07-09T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"None","quality_controlled":"1","_id":"22315","status":"public","author":[{"full_name":"Bao, Zhulatai","first_name":"Zhulatai","last_name":"Bao"},{"first_name":"Huihui","full_name":"Wang, Huihui","last_name":"Wang"},{"first_name":"Ai","full_name":"Zhang, Ai","last_name":"Zhang"},{"full_name":"Gao, Ruxi","first_name":"Ruxi","last_name":"Gao"},{"last_name":"Gu","full_name":"Gu, Wen","first_name":"Wen"},{"last_name":"Fan","first_name":"Ni","full_name":"Fan, Ni"},{"last_name":"Friml","id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","full_name":"Friml, Jiří","first_name":"Jiří"},{"first_name":"Yuzhou","full_name":"Zhang, Yuzhou","last_name":"Zhang"}],"intvolume":"       393","doi":"10.1126/science.adw6568","fulldoi":"https://doi.org/10.1126/science.adw6568","article_number":"eadw6568","external_id":{"pmid":["42424472"]},"scopus_import":"1","article_processing_charge":"No"},{"_id":"23044","quality_controlled":"1","status":"public","author":[{"last_name":"Yang","first_name":"D.","full_name":"Yang, D."},{"full_name":"Hennawi, J. F.","first_name":"J. F.","last_name":"Hennawi"},{"last_name":"Guarneri","first_name":"F.","full_name":"Guarneri, F."},{"last_name":"Wolf","full_name":"Wolf, J.","first_name":"J."},{"full_name":"Belladitta, S.","first_name":"S.","last_name":"Belladitta"},{"last_name":"Schindler","first_name":"J. T.","full_name":"Schindler, J. T."},{"last_name":"Hughes","full_name":"Hughes, A. C.N.","first_name":"A. C.N."},{"last_name":"Bañados","first_name":"E.","full_name":"Bañados, E."},{"full_name":"Mortlock, D. J.","first_name":"D. J.","last_name":"Mortlock"},{"full_name":"Yang, J.","first_name":"J.","last_name":"Yang"},{"last_name":"Wang","full_name":"Wang, F.","first_name":"F."},{"last_name":"Fan","full_name":"Fan, X.","first_name":"X."},{"last_name":"Jahnke","first_name":"K.","full_name":"Jahnke, K."},{"first_name":"D.","full_name":"Stern, D.","last_name":"Stern"},{"full_name":"Willott, C. J.","first_name":"C. J.","last_name":"Willott"},{"first_name":"A. J.","full_name":"Barth, A. J.","last_name":"Barth"},{"first_name":"H. J.A.","full_name":"Rottgering, H. J.A.","last_name":"Rottgering"},{"full_name":"Varadaraj, R. G.","first_name":"R. G.","last_name":"Varadaraj"},{"last_name":"Decarli","first_name":"R.","full_name":"Decarli, R."},{"last_name":"Eilers","first_name":"A. C.","full_name":"Eilers, A. C."},{"first_name":"M.","full_name":"Ezziati, M.","last_name":"Ezziati"},{"last_name":"Fu","first_name":"Y.","full_name":"Fu, Y."},{"last_name":"Huang","first_name":"J.","full_name":"Huang, J."},{"full_name":"Jin, X.","first_name":"X.","last_name":"Jin"},{"last_name":"Kang","full_name":"Kang, Y.","first_name":"Y."},{"first_name":"L. N.","full_name":"Martinez-Ramirez, L. N.","last_name":"Martinez-Ramirez"},{"last_name":"Matsuoka","full_name":"Matsuoka, Y.","first_name":"Y."},{"last_name":"Onoue","full_name":"Onoue, M.","first_name":"M."},{"last_name":"Pello","first_name":"R.","full_name":"Pello, R."},{"last_name":"Remigio","first_name":"R. P.","full_name":"Remigio, R. 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M.","full_name":"Zerbi, F. M."},{"first_name":"E.","full_name":"Zucca, E.","last_name":"Zucca"},{"last_name":"Fabbian","full_name":"Fabbian, G.","first_name":"G."},{"last_name":"Huertas-Company","full_name":"Huertas-Company, M.","first_name":"M."},{"full_name":"Martín-Fleitas, J.","first_name":"J.","last_name":"Martín-Fleitas"},{"first_name":"P.","full_name":"Monaco, P.","last_name":"Monaco"},{"full_name":"Scottez, V.","first_name":"V.","last_name":"Scottez"},{"first_name":"M.","full_name":"Viel, M.","last_name":"Viel"}],"intvolume":"       711","doi":"10.1051/0004-6361/202658883","oa_version":"Published Version","DOAJ_listed":"1","ddc":["520"],"fulldoi":"https://doi.org/10.1051/0004-6361/202658883","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_number":"A104","external_id":{"arxiv":["2607.03432"]},"arxiv":1,"OA_place":"publisher","article_processing_charge":"No","scopus_import":"1","PlanS_conform":"1","day":"01","language":[{"iso":"eng"}],"OA_type":"diamond","publication_status":"published","file_date_updated":"2026-10-12T06:20:29Z","department":[{"_id":"JoMa"}],"year":"2026","date_published":"2026-07-01T00:00:00Z","abstract":[{"lang":"eng","text":"We report the discovery of 31 new high-z quasars in the redshift range 6.6 < z < 7.8. These quasars were selected from approximately 3000 deg2 of sky covered during the first 1.5 years of the Euclid Wide Survey, representing the initial results of the Euclid high-z quasar search. Our candidate selection employed multiple machine-learning and probabilistic techniques applied to the EuclidIE, YE, JE, and HE images, supplemented by ancillary z-band data when available. Spectroscopic follow-up observations were carried out with Keck, Magellan, and the Large Binocular Telescope (LBT). Among the new discoveries, there are 12 quasars at z ≥ 7, more than doubling the number of previously known quasars at z ≥ 7. The newly discovered quasars exhibit 21.2 < JE < 23.2 (−25.5 < M1450 < −23.6), extending quasar studies to the faint end of the quasar luminosity function (QLF) at z ≳ 7. The quasar with the highest-z, EUCL J172902.75+641018.1 at z ≈ 7.77, sets the new redshift record for the most distant quasar ever reported. These discoveries demonstrate Euclid’s transformative role in high-z quasar discovery and set the stage for future follow-up studies of the early galaxies hosting quasars, supermassive black hole growth, and the intergalactic medium in the epoch of reionisation."}],"researchdata_availability":"no","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"mla":"Yang, D., et al. “Euclid: Discovery of 31 New Quasars at 6.6 &#60; z &#60; 7.8.” <i>Astronomy &#38; Astrophysics</i>, vol. 711, A104, EDP Sciences, 2026, doi:<a href=\"https://doi.org/10.1051/0004-6361/202658883\">10.1051/0004-6361/202658883</a>.","ista":"Yang D et al. 2026. Euclid: Discovery of 31 new quasars at 6.6 &#60; z &#60; 7.8. Astronomy &#38; Astrophysics. 711, A104.","chicago":"Yang, D., J. F. Hennawi, F. Guarneri, J. Wolf, S. Belladitta, J. T. Schindler, A. C.N. Hughes, et al. “Euclid: Discovery of 31 New Quasars at 6.6 &#60; z &#60; 7.8.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2026. <a href=\"https://doi.org/10.1051/0004-6361/202658883\">https://doi.org/10.1051/0004-6361/202658883</a>.","ama":"Yang D, Hennawi JF, Guarneri F, et al. Euclid: Discovery of 31 new quasars at 6.6 &#60; z &#60; 7.8. <i>Astronomy &#38; Astrophysics</i>. 2026;711. doi:<a href=\"https://doi.org/10.1051/0004-6361/202658883\">10.1051/0004-6361/202658883</a>","apa":"Yang, D., Hennawi, J. F., Guarneri, F., Wolf, J., Belladitta, S., Schindler, J. T., … Viel, M. (2026). Euclid: Discovery of 31 new quasars at 6.6 &#60; z &#60; 7.8. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202658883\">https://doi.org/10.1051/0004-6361/202658883</a>","ieee":"D. Yang <i>et al.</i>, “Euclid: Discovery of 31 new quasars at 6.6 &#60; z &#60; 7.8,” <i>Astronomy &#38; Astrophysics</i>, vol. 711. EDP Sciences, 2026.","short":"D. Yang, J.F. Hennawi, F. Guarneri, J. Wolf, S. Belladitta, J.T. Schindler, A.C.N. Hughes, E. Bañados, D.J. Mortlock, J. Yang, F. Wang, X. Fan, K. Jahnke, D. Stern, C.J. Willott, A.J. Barth, H.J.A. Rottgering, R.G. Varadaraj, R. Decarli, A.C. Eilers, M. Ezziati, Y. Fu, J. Huang, X. Jin, Y. Kang, L.N. Martinez-Ramirez, Y. Matsuoka, M. Onoue, R. Pello, R.P. Remigio, W.L. Tee, B. Venemans, G. Vietri, B. Wang, L.J. Abbo, H. Atek, S. Bisogni, S.E.I. Bosman, R.A.A. Bowler, C.J. Conselice, F.B. Davies, C.M. Gutierrez, Y. Harikane, K. Rubinur, C.C. Lovell, M. Magliocchetti, J.J. Matthee, F. Ricci, M. Scialpi, D. Scott, L. Spinoglio, F. Tarsitano, Y. Toba, F. Walter, J.R. Weaver, G. Zamorani, B. Altieri, A. Amara, S. Andreon, H. Aussel, C. Baccigalupi, M. Baldi, A. Balestra, S. Bardelli, P. Battaglia, A. Biviano, E. Branchini, M. Brescia, S. Camera, G. Cañas-Herrera, V. Capobianco, C. Carbone, J. Carretero, M. Castellano, G. Castignani, S. Cavuoti, K.C. Chambers, A. Cimatti, C. Colodro-Conde, G. Congedo, L. Conversi, Y. Copin, F. Courbin, H.M. Courtois, M. Cropper, J.C. Cuillandre, H. Degaudenzi, G. De Lucia, C. Dolding, H. Dole, M. Douspis, F. Dubath, X. Dupac, S. Dusini, S. Escoffier, M. Farina, R. Farinelli, S. Ferriol, F. Finelli, N. Fourmanoit, M. Frailis, E. Franceschi, M. Fumana, S. Galeotta, K. George, B. Gillis, C. Giocoli, P. Gómez-Alvarez, J. Gracia-Carpio, A. Grazian, F. Grupp, L. Guzzo, S. Gwyn, S.V.H. Haugan, H. Hoekstra, W. Holmes, I.M. Hook, F. Hormuth, A. Hornstrup, M. Jhabvala, S. Kermiche, B. Kubik, K. Kuijken, M. Kümmel, M. Kunz, H. Kurki-Suonio, A.M.C. Le Brun, S. Ligori, P.B. Lilje, V. Lindholm, I. Lloro, G. Mainetti, D. Maino, E. Maiorano, O. Mansutti, O. Marggraf, M. Martinelli, N. Martinet, F. Marulli, R.J. Massey, H.J. Mccracken, E. Medinaceli, S. Mei, Y. Mellier, M. Meneghetti, E. Merlin, G. Meylan, J.J. Mohr, A. Mora, M. Moresco, L. Moscardini, E. Munari, R. Nakajima, C. Neissner, R.C. Nichol, S.M. Niemi, C. Padilla, S. Paltani, F. Pasian, K. Pedersen, W.J. Percival, V. Pettorino, S. Pires, G. Polenta, M. Poncet, L.A. Popa, L. Pozzetti, G.D. Racca, F. Raison, R. Rebolo, A. Renzi, J. Rhodes, G. Riccio, H.W. Rix, E. Romelli, M. Roncarelli, C. Rosset, B. Rusholme, R. Saglia, Z. Sakr, D. Sapone, M. Sauvage, M. Schirmer, P. Schneider, T. Schrabback, A. Secroun, G. Seidel, S. Serrano, E. Sihvola, P. Simon, C. Sirignano, G. Sirri, L. Stanco, J. Steinwagner, P. Tallada-Crespí, I. Tereno, N. Tessore, S. Toft, R. Toledo-Moreo, F. Torradeflot, I. Tutusaus, L. Valenziano, J. Valiviita, T. Vassallo, Y. Wang, J. Weller, F.M. Zerbi, E. Zucca, G. Fabbian, M. Huertas-Company, J. Martín-Fleitas, P. Monaco, V. Scottez, M. Viel, Astronomy &#38; Astrophysics 711 (2026)."},"month":"07","title":"Euclid: Discovery of 31 new quasars at 6.6 < z < 7.8","publisher":"EDP Sciences","type":"journal_article","publication_identifier":{"eissn":["1432-0746"],"issn":["0004-6361"]},"file":[{"creator":"dernst","relation":"main_file","checksum":"055c80a2cd071884e2804ef17dcf1e16","file_size":14151909,"content_type":"application/pdf","access_level":"open_access","success":1,"date_created":"2026-10-12T06:20:29Z","date_updated":"2026-10-12T06:20:29Z","file_name":"2026_AstronomyAstrophysics_Yang.pdf","file_id":"23097"}],"article_type":"original","supplementarymaterial":"yes","date_updated":"2026-10-20T08:15:12Z","oa":1,"dataavailabilitystatement":"This work has made use of Euclid data from the European Space Agency (ESA) mission Euclid. The quasar cutouts are available at https://doi.org/10.57780/esa-50769fd. The discovery spectra are available from the corresponding author upon reasonable request.","date_created":"2026-10-04T22:01:54Z","volume":711,"acknowledgement":"D. Yang acknowledges helpful discussions with members of the ENIGMA group at UC Santa Barbara and Leiden University, in particular Elia Pizzati, Silvia Onorato, and Diego González for their valuable feedback. D. Yang thanks Shane Bechtel for assistance during observations, and acknowledges the early contributions of Riccardo Nanni, which helped lay the foundation for this work. D. Yang and J. F. Hennawi acknowledge support from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (grant agreement No 885301). J. F. Hennawi acknowledges support from NSF grant No. 2307180. F. Guarneri and J.-T. Schindler are supported by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) – Project number 518006966. F. Wang acknowledges support from NSF award AST-2513040. R. Decarli acknowledges support from the INAF GO 2022 grant “The birth of the giants: JWST sheds light on the build-up of quasars at cosmic dawn”, INAF Minigrant 2024 “The interstellar medium at high redshift”, and by the PRIN MUR “2022935STW”, RFF M4.C2.1.1, CUP J53D23001570006 and C53D23000950006. S. E. I. Bosman is supported by the Deutsche Forschungsgemeinschaft (DFG) under Emmy Noether grant number BO 5771/1-1. Y. Harikane acknowledges support from the Japan Society for the Promotion of Science (JSPS) Grant-in-Aid for Scientific Research (24H00245), the JSPS Core-to-Core Program (JPJSCCA20210003), and the JSPS International Leading Research (22K21349). J. R. Weaver acknowledges that support for this work was provided by The Brinson Foundation through a Brinson Prize Fellowship grant. The Euclid Consortium acknowledges the European Space Agency and a number of agencies and institutes that have supported the development of Euclid, in particular the Agenzia Spaziale Italiana, the Austrian Forschungsförderungsgesellschaft funded through BMIMI, the Belgian Science Policy, the Canadian Euclid Consortium, the Deutsches Zentrum für Luft- und Raumfahrt, the DTU Space and the Niels Bohr Institute in Denmark, the French Centre National d’Etudes Spatiales, the Fundação para a Ciência e a Tecnologia, the Hungarian Academy of Sciences, the Ministerio de Ciencia, Innovación y Universidades, the National Aeronautics and Space Administration, the National Astronomical Observatory of Japan, the Netherlandse Onderzoekschool Voor Astronomie, the Norwegian Space Agency, the Research Council of Finland, the Romanian Space Agency, the State Secretariat for Education, Research, and Innovation (SERI) at the Swiss Space Office (SSO), and the United Kingdom Space Agency. A complete and detailed list is available on the Euclid web site (www.euclid-ec.org). Some of the data presented herein were obtained at Keck Observatory, which is a private 501(c)3 non-profit organization operated as a scientific partnership among the California Institute of Technology, the University of California, and the National Aeronautics and Space Administration. The Observatory was made possible by the generous financial support of the W. M. Keck Foundation. The authors wish to recognise and acknowledge the very significant cultural role and reverence that the summit of Maunakea has always had within the Native Hawaiian community. We are most fortunate to have the opportunity to conduct observations from this mountain. This paper includes data gathered with the 6.5 meter Magellan Telescopes located at Las Campanas Observatory, Chile. This work uses LBT data from programmes: MPIA-2025A-007 and MPIA-2025B-004. The LBT is an international collaboration among institutions in the United States, Italy and Germany. LBT Corporation partners are: The University of Arizona on behalf of the Arizona university system; Istituto Nazionale di Astrofisica, Italy; LBT Beteiligungsgesellschaft, Germany, representing the Max-Planck Society, the Astrophysical Institute Potsdam, and Heidelberg University; The Ohio State University, and The Research Corporation, on behalf of The University of Notre Dame, University of Minnesota, and University of Virginia, LOFAR data products were provided by the LOFAR Surveys Key Science project (LSKSP; https://lofar-surveys.org/) and were derived from observations with the International LOFAR Telescope (ILT). LOFAR is the Low Frequency Array designed and constructed by ASTRON. It has observing, data processing, and data storage facilities in several countries, which are owned by various parties (each with their own funding sources), and which are collectively operated by the ILT foundation under a joint scientific policy. The efforts of the LSKSP have benefited from funding from the European Research Council, NOVA, NWO, CNRS-INSU, the SURF Co-operative, the UK Science and Technology Funding Council and the Jülich Supercomputing Centre. We make use of z-band imaging from the Wide Imaging with Subaru HSC of the Euclid Sky (WISHES) program operated by the Subaru Telescope, which is operated by the National Astronomical Observatory of Japan. We also make use of z-band imaging from the Dark Energy Survey (DES), based on observations obtained at the Cerro Tololo Inter-American Observatory, National Optical Astronomy Observatory, which is operated by AURA under a cooperative agreement with the National Science Foundation. This work made use of NumPy (Harris et al. 2020), SciPy (Virtanen et al. 2020), Astropy (Astropy Collaboration 2013, 2018, 2022), PypeIt (Prochaska et al. 2020), Sculptor (Schindler 2022), condXD (Kang et al. 2025), pysersic (Pasha & Miller 2023), Matplotlib (Hunter 2007), corner.py (Foreman-Mackey 2016), healpy (Zonca et al. 2020).","has_accepted_license":"1","publication":"Astronomy & Astrophysics","das_tickbox":"1"},{"oa_version":"Published Version","DOAJ_listed":"1","author":[{"last_name":"Llerena","first_name":"M.","full_name":"Llerena, M."},{"last_name":"Pentericci","full_name":"Pentericci, L.","first_name":"L."},{"first_name":"R.","full_name":"Amorín, R.","last_name":"Amorín"},{"last_name":"Ferrara","full_name":"Ferrara, A.","first_name":"A."},{"first_name":"M.","full_name":"Dickinson, M.","last_name":"Dickinson"},{"first_name":"F.","full_name":"Arevalo-Gonzalez, F.","last_name":"Arevalo-Gonzalez"},{"full_name":"Calabrò, A.","first_name":"A.","last_name":"Calabrò"},{"last_name":"Napolitano","first_name":"L.","full_name":"Napolitano, L."},{"id":"edaf889c-c7cd-11ef-ab1b-bb28c431bd29","last_name":"Mascia","first_name":"Sara","full_name":"Mascia, Sara"},{"full_name":"Arrabal Haro, P.","first_name":"P.","last_name":"Arrabal Haro"},{"last_name":"Begley","first_name":"R.","full_name":"Begley, R."},{"last_name":"Cleri","first_name":"N. J.","full_name":"Cleri, N. J."},{"full_name":"Davis, K.","first_name":"K.","last_name":"Davis"},{"last_name":"Hu","full_name":"Hu, W.","first_name":"W."},{"last_name":"Kartaltepe","full_name":"Kartaltepe, J. S.","first_name":"J. S."},{"last_name":"Koekemoer","full_name":"Koekemoer, A. M.","first_name":"A. M."},{"full_name":"Lucas, R. A.","first_name":"R. A.","last_name":"Lucas"},{"last_name":"Mcgrath","first_name":"E.","full_name":"Mcgrath, E."},{"last_name":"Mcleod","first_name":"D. J.","full_name":"Mcleod, D. J."},{"last_name":"Papovich","full_name":"Papovich, C.","first_name":"C."},{"last_name":"Stanton","first_name":"T. M.","full_name":"Stanton, T. M."},{"full_name":"Taylor, A. J.","first_name":"A. J.","last_name":"Taylor"},{"first_name":"R.","full_name":"Tripodi, R.","last_name":"Tripodi"},{"full_name":"Wang, X.","first_name":"X.","last_name":"Wang"},{"last_name":"Yung","first_name":"L. Y.A.","full_name":"Yung, L. Y.A."}],"_id":"23049","status":"public","quality_controlled":"1","intvolume":"       708","doi":"10.1051/0004-6361/202557897","fulldoi":"https://doi.org/10.1051/0004-6361/202557897","ddc":["520"],"article_number":"A152","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"external_id":{"arxiv":["2510.25647"]},"scopus_import":"1","PlanS_conform":"1","arxiv":1,"article_processing_charge":"No","OA_place":"publisher","OA_type":"diamond","language":[{"iso":"eng"}],"day":"01","department":[{"_id":"JoMa"}],"file_date_updated":"2026-10-12T07:19:26Z","publication_status":"published","year":"2026","citation":{"mla":"Llerena, M., et al. “Extreme Equivalent-Width-Selected Low-Mass Starbursts at z = 4 − 9: Insights into Their Role in Cosmic Reionization.” <i>Astronomy &#38; Astrophysics</i>, vol. 708, A152, EDP Sciences, 2026, doi:<a href=\"https://doi.org/10.1051/0004-6361/202557897\">10.1051/0004-6361/202557897</a>.","ista":"Llerena M, Pentericci L, Amorín R, Ferrara A, Dickinson M, Arevalo-Gonzalez F, Calabrò A, Napolitano L, Mascia S, Arrabal Haro P, Begley R, Cleri NJ, Davis K, Hu W, Kartaltepe JS, Koekemoer AM, Lucas RA, Mcgrath E, Mcleod DJ, Papovich C, Stanton TM, Taylor AJ, Tripodi R, Wang X, Yung LYA. 2026. Extreme equivalent-width-selected low-mass starbursts at z = 4 − 9: Insights into their role in cosmic reionization. Astronomy &#38; Astrophysics. 708, A152.","ieee":"M. Llerena <i>et al.</i>, “Extreme equivalent-width-selected low-mass starbursts at z = 4 − 9: Insights into their role in cosmic reionization,” <i>Astronomy &#38; Astrophysics</i>, vol. 708. EDP Sciences, 2026.","apa":"Llerena, M., Pentericci, L., Amorín, R., Ferrara, A., Dickinson, M., Arevalo-Gonzalez, F., … Yung, L. Y. A. (2026). Extreme equivalent-width-selected low-mass starbursts at z = 4 − 9: Insights into their role in cosmic reionization. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202557897\">https://doi.org/10.1051/0004-6361/202557897</a>","short":"M. Llerena, L. Pentericci, R. Amorín, A. Ferrara, M. Dickinson, F. Arevalo-Gonzalez, A. Calabrò, L. Napolitano, S. Mascia, P. Arrabal Haro, R. Begley, N.J. Cleri, K. Davis, W. Hu, J.S. Kartaltepe, A.M. Koekemoer, R.A. Lucas, E. Mcgrath, D.J. Mcleod, C. Papovich, T.M. Stanton, A.J. Taylor, R. Tripodi, X. Wang, L.Y.A. Yung, Astronomy &#38; Astrophysics 708 (2026).","ama":"Llerena M, Pentericci L, Amorín R, et al. Extreme equivalent-width-selected low-mass starbursts at z = 4 − 9: Insights into their role in cosmic reionization. <i>Astronomy &#38; Astrophysics</i>. 2026;708. doi:<a href=\"https://doi.org/10.1051/0004-6361/202557897\">10.1051/0004-6361/202557897</a>","chicago":"Llerena, M., L. Pentericci, R. Amorín, A. Ferrara, M. Dickinson, F. Arevalo-Gonzalez, A. Calabrò, et al. “Extreme Equivalent-Width-Selected Low-Mass Starbursts at z = 4 − 9: Insights into Their Role in Cosmic Reionization.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2026. <a href=\"https://doi.org/10.1051/0004-6361/202557897\">https://doi.org/10.1051/0004-6361/202557897</a>."},"month":"04","title":"Extreme equivalent-width-selected low-mass starbursts at z = 4 − 9: Insights into their role in cosmic reionization","abstract":[{"lang":"eng","text":"We investigate the properties of extreme emission line galaxies (EELGs) at z = 4 − 9 and their role in reionization. Compact, low-mass galaxies with intense optical emission lines are linked to elevated specific star formation rates (sSFRs) and recent bursts of star formation. Feedback in these systems may enable the leakage of ionizing radiation into the intergalactic medium. Using JWST/NIRSpec spectroscopy from the CAPERS, CEERS, and RUBIES surveys, we compiled 160 NIRCam-selected EELGs in the EGS field. These galaxies show extreme rest-frame equivalent widths (EWs), with a median EW([O III]+Hβ) = 1616 Å and EW(Hα) = 763 Å. They are low-mass (median log(M★/M⊙) = 8.26) with high sSFRs (median 43 Gyr−1), above the z ∼ 6 main sequence. UV slopes are diverse, with a median value of β = −2.0, and only 7% have extremely blue continua (β < −2.6). Emission-line diagnostics suggest stellar populations as the primary ionizing source, although an AGN fraction of 14% cannot be entirely ruled out. These galaxies are efficient ionizing photon producers, with median log(ξion [Hz erg−1]) = 25.37, exceeding typical values at similar redshifts. Escape fractions, however, are heterogeneous: 16% of EELGs at z < 7 show escape fractions > 5% for both Lyα and LyC photons, while 82% lack detectable Lyα emission. The median inferred LyC escape fraction is modest (5%) but enhanced in compact super-Eddington systems with sSFR > 25 Gyr−1. These results indicate that EELGs contribute approximately 16 − 40% of the total ionizing emissivity required to sustain hydrogen reionization. EELGs are extremely compact, with a median effective radius of 0.49 kpc, and exhibit a recent star formation burst. Our analysis indicates that sSFR and star formation rate surface density are the primary drivers of their extreme emission line strengths."}],"date_published":"2026-04-01T00:00:00Z","researchdata_availability":"no","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"EDP Sciences","type":"journal_article","publication_identifier":{"eissn":["1432-0746"],"issn":["0004-6361"]},"article_type":"original","file":[{"date_created":"2026-10-12T07:19:26Z","file_id":"23100","file_name":"2026_AstronomyAstrophysics_Llerena.pdf","date_updated":"2026-10-12T07:19:26Z","checksum":"d678534203385bec7579e68e12cc09b4","creator":"dernst","relation":"main_file","access_level":"open_access","success":1,"file_size":5918938,"content_type":"application/pdf"}],"date_updated":"2026-10-20T08:15:59Z","supplementarymaterial":"yes","dataavailabilitystatement":"Table A.1 is available at the CDS via https://cdsarc.cds.unistra.fr/viz-bin/cat/J/A+A/708/A152","oa":1,"date_created":"2026-10-04T22:01:55Z","has_accepted_license":"1","acknowledgement":"We thank the anonymous referee for the thorough review and constructive suggestions that significantly improved this paper. We also thank Sophia Flury for valuable feedback and insightful comments, which helped refine our interpretation of the results. MLl acknowledges support from the INAF Large Grant 2022 “Extragalactic Surveys with JWST” (PI L. Pentericci), the PRIN 2022 MUR project 2022CB3PJ3 – First Light And Galaxy aSsembly (FLAGS) funded by the European Union – Next Generation EU, the INAF Mini-grant 2024 “Galaxies in the epoch of Reionization and their analogs at lower redshift” (PI M. Llerena), and the Large Grant RF 2023 F.O. 1.05.23.01.11 “The MOONS Extragalactic Survey”. RA acknowledges support of Grant PID2023-147386NB-I00 funded by MICIU/AEI/10.13039/501100011033 and by ERDF/EU, and the Severo Ochoa award to the IAA-CSIC CEX2021-001131-S. This work is based on observations made with the NASA/ESA/CSA James Webb Space Telescope, obtained at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Incorporated, under NASA contract NAS5-03127. Support for program number GO-6368 was provided through a grant from the STScI under NASA contract NAS5-03127. The data were obtained from the Mikulski Archive for Space Telescopes (MAST) at the Space Telescope Science Institute. These observations are associated with program #6368, and can be accessed via doi. Some of the data products presented herein were retrieved from the Dawn JWST Archive (DJA). DJA is an initiative of the Cosmic Dawn Center (DAWN), which is funded by the Danish National Research Foundation under grant DNRF140. These observations are associated with programs #1345, #2750, and #4233. This work has made extensive use of Python packages astropy (Astropy Collaboration 2018), numpy (Harris et al. 2020), Matplotlib (Hunter 2007) and LiMe (Fernández et al. 2024).","das_tickbox":"1","publication":"Astronomy & Astrophysics","volume":708},{"year":"2026","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","researchdata_availability":"no","date_published":"2026-04-01T00:00:00Z","abstract":[{"text":"The resonant scattering nature of Lyα photons interacting with neutral hydrogen makes Lyα emitters (LAEs) robust tracers of the intergalactic neutral hydrogen fraction, and thus sensitive probes of cosmic reionization. We present an extensive study of the Lyα evolution from galaxies at 4.5 ≤ z ≤ 11 in the UDS field, observed as part of the CAPERS survey, and complemented with spectra from the DAWN JWST Archive. The combined sample includes 651 spectroscopically confirmed Lyα-break galaxies, among which we find 73 S/N > 3 LAEs in JWST-NIRSpec PRISM spectra. We trace the redshift evolution of the LAE fraction with EW0 > 25 Å (XLyα) between z = 5 and z = 9, extending such an analysis to the UDS field for the first time. At z = 5 and 6, the UDS results agree with the average JWST XLyα values from multiple fields. However, JWST measurements are consistently lower than ground-based results. To investigate this, we compare JWST observations to a population of star-forming galaxies at z ∼ 6 observed with VLT-FORS2. We find that a Lyα slit-loss of 35 ± 10% in JWST spectra accounts for the offset, as the resonant Lyα emission is more spatially extended than the stellar continuum. From z = 6 to 7, the UDS field shows a significant drop in Lyα visibility, from which we infer a neutral hydrogen fraction of XHI = 0.7–0.9. Finally, we identify two robust ionized bubbles at z = 7.29 and 7.77, with radii of Rion = 0.6 and 0.5 physical Mpc and photometric overdensities of N/⟨N⟩ = 3 and 4, based on candidate counts down to the photometric completeness limit. Compared to the large ionized region at z ∼ 7 in the EGS field, these results indicate significant field-to-field variation, supporting a patchy, inhomogeneous reionization process.","lang":"eng"}],"month":"04","title":"Lyα visibility from z = 4.5 to 11 in the UDS field: Evidence for a high neutral hydrogen fraction and small ionized bubbles at z ∼ 7","citation":{"apa":"Napolitano, L., Pentericci, L., Dickinson, M., Arrabal Haro, P., Taylor, A. J., Calabrò, A., … Weiner, B. J. (2026). Lyα visibility from z = 4.5 to 11 in the UDS field: Evidence for a high neutral hydrogen fraction and small ionized bubbles at z ∼ 7. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202556912\">https://doi.org/10.1051/0004-6361/202556912</a>","ieee":"L. Napolitano <i>et al.</i>, “Lyα visibility from z = 4.5 to 11 in the UDS field: Evidence for a high neutral hydrogen fraction and small ionized bubbles at z ∼ 7,” <i>Astronomy &#38; Astrophysics</i>, vol. 708. EDP Sciences, 2026.","short":"L. Napolitano, L. Pentericci, M. Dickinson, P. Arrabal Haro, A.J. Taylor, A. Calabrò, A. Bhagwat, P. Santini, F. Arevalo-Gonzalez, R. Begley, M. Castellano, B. Ciardi, C.T. Donnan, D. Dottorini, J.S. Dunlop, S.L. Finkelstein, A. Fontana, M. Giavalisco, M. Hirschmann, I. Jung, A.M. Koekemoer, V. Kokorev, M. Llerena, R.A. Lucas, S. Mascia, E. Merlin, P.G. Pérez-González, T.M. Stanton, R. Tripodi, X. Wang, B.J. Weiner, Astronomy &#38; Astrophysics 708 (2026).","chicago":"Napolitano, L., L. Pentericci, M. Dickinson, P. Arrabal Haro, A. J. Taylor, A. Calabrò, A. Bhagwat, et al. “Lyα Visibility from z = 4.5 to 11 in the UDS Field: Evidence for a High Neutral Hydrogen Fraction and Small Ionized Bubbles at z ∼ 7.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2026. <a href=\"https://doi.org/10.1051/0004-6361/202556912\">https://doi.org/10.1051/0004-6361/202556912</a>.","ama":"Napolitano L, Pentericci L, Dickinson M, et al. Lyα visibility from z = 4.5 to 11 in the UDS field: Evidence for a high neutral hydrogen fraction and small ionized bubbles at z ∼ 7. <i>Astronomy &#38; Astrophysics</i>. 2026;708. doi:<a href=\"https://doi.org/10.1051/0004-6361/202556912\">10.1051/0004-6361/202556912</a>","ista":"Napolitano L, Pentericci L, Dickinson M, Arrabal Haro P, Taylor AJ, Calabrò A, Bhagwat A, Santini P, Arevalo-Gonzalez F, Begley R, Castellano M, Ciardi B, Donnan CT, Dottorini D, Dunlop JS, Finkelstein SL, Fontana A, Giavalisco M, Hirschmann M, Jung I, Koekemoer AM, Kokorev V, Llerena M, Lucas RA, Mascia S, Merlin E, Pérez-González PG, Stanton TM, Tripodi R, Wang X, Weiner BJ. 2026. Lyα visibility from z = 4.5 to 11 in the UDS field: Evidence for a high neutral hydrogen fraction and small ionized bubbles at z ∼ 7. Astronomy &#38; Astrophysics. 708, A102.","mla":"Napolitano, L., et al. “Lyα Visibility from z = 4.5 to 11 in the UDS Field: Evidence for a High Neutral Hydrogen Fraction and Small Ionized Bubbles at z ∼ 7.” <i>Astronomy &#38; Astrophysics</i>, vol. 708, A102, EDP Sciences, 2026, doi:<a href=\"https://doi.org/10.1051/0004-6361/202556912\">10.1051/0004-6361/202556912</a>."},"language":[{"iso":"eng"}],"day":"01","OA_type":"diamond","publication_status":"published","department":[{"_id":"JoMa"}],"file_date_updated":"2026-10-12T07:09:27Z","external_id":{"arxiv":["2508.14171"]},"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_number":"A102","article_processing_charge":"No","OA_place":"publisher","arxiv":1,"scopus_import":"1","PlanS_conform":"1","intvolume":"       708","doi":"10.1051/0004-6361/202556912","author":[{"last_name":"Napolitano","full_name":"Napolitano, L.","first_name":"L."},{"first_name":"L.","full_name":"Pentericci, L.","last_name":"Pentericci"},{"last_name":"Dickinson","full_name":"Dickinson, M.","first_name":"M."},{"last_name":"Arrabal Haro","full_name":"Arrabal Haro, P.","first_name":"P."},{"last_name":"Taylor","full_name":"Taylor, A. J.","first_name":"A. J."},{"last_name":"Calabrò","first_name":"A.","full_name":"Calabrò, A."},{"full_name":"Bhagwat, A.","first_name":"A.","last_name":"Bhagwat"},{"last_name":"Santini","first_name":"P.","full_name":"Santini, P."},{"last_name":"Arevalo-Gonzalez","full_name":"Arevalo-Gonzalez, F.","first_name":"F."},{"first_name":"R.","full_name":"Begley, R.","last_name":"Begley"},{"last_name":"Castellano","first_name":"M.","full_name":"Castellano, M."},{"full_name":"Ciardi, B.","first_name":"B.","last_name":"Ciardi"},{"full_name":"Donnan, C. T.","first_name":"C. T.","last_name":"Donnan"},{"full_name":"Dottorini, D.","first_name":"D.","last_name":"Dottorini"},{"first_name":"J. S.","full_name":"Dunlop, J. S.","last_name":"Dunlop"},{"last_name":"Finkelstein","full_name":"Finkelstein, S. L.","first_name":"S. L."},{"last_name":"Fontana","full_name":"Fontana, A.","first_name":"A."},{"last_name":"Giavalisco","first_name":"M.","full_name":"Giavalisco, M."},{"last_name":"Hirschmann","full_name":"Hirschmann, M.","first_name":"M."},{"first_name":"I.","full_name":"Jung, I.","last_name":"Jung"},{"last_name":"Koekemoer","first_name":"A. M.","full_name":"Koekemoer, A. M."},{"first_name":"V.","full_name":"Kokorev, V.","last_name":"Kokorev"},{"first_name":"M.","full_name":"Llerena, M.","last_name":"Llerena"},{"first_name":"R. A.","full_name":"Lucas, R. A.","last_name":"Lucas"},{"id":"edaf889c-c7cd-11ef-ab1b-bb28c431bd29","last_name":"Mascia","first_name":"Sara","full_name":"Mascia, Sara"},{"full_name":"Merlin, E.","first_name":"E.","last_name":"Merlin"},{"last_name":"Pérez-González","first_name":"P. G.","full_name":"Pérez-González, P. G."},{"last_name":"Stanton","first_name":"T. M.","full_name":"Stanton, T. M."},{"full_name":"Tripodi, R.","first_name":"R.","last_name":"Tripodi"},{"last_name":"Wang","first_name":"X.","full_name":"Wang, X."},{"last_name":"Weiner","full_name":"Weiner, B. J.","first_name":"B. J."}],"_id":"23050","status":"public","quality_controlled":"1","oa_version":"Published Version","ddc":["520"],"fulldoi":"https://doi.org/10.1051/0004-6361/202556912","date_created":"2026-10-04T22:01:55Z","volume":708,"publication":"Astronomy & Astrophysics","das_tickbox":"0","has_accepted_license":"1","acknowledgement":"We thank the anonymous referee for the constructive feedback provided. LN acknowledges support from grant “Progetti per Avvio alla Ricerca – Tipo 1, Unveiling Cosmic Dawn: Galaxy Evolution with CAPERS” (AR1241906F947685) and from PRIN 2022 MUR project 2022CB3PJ3 – First Light And Galaxy aSsembly (FLAGS) funded by the European Union – Next Generation EU. LN, LP, AB, and BC acknowledge support from the ERC synergy grant 101166930 – RECAP. This work is based on observations made with the NASA/ESA/CSA James Webb Space Telescope, obtained at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Incorporated, under NASA contract NAS5-03127. These observations are associated with programs #6368, #4233, #1215, #2565, and #3543. Support for program number GO-6368 was provided through a grant from the STScI under NASA contract NAS5-03127. The data were obtained from the Mikulski Archive for Space Telescopes (MAST) at the Space Telescope Science Institute. These observations can be accessed via DOI. Some of the data products presented in this work were retrieved from the Dawn JWST Archive (DJA). DJA is an initiative of the Cosmic Dawn Center (DAWN), which is funded by the Danish National Research Foundation under grant DNRF140.","oa":1,"file":[{"content_type":"application/pdf","file_size":3265893,"success":1,"access_level":"open_access","relation":"main_file","creator":"dernst","checksum":"adff12137f194affedd27fa07c82e062","date_updated":"2026-10-12T07:09:27Z","file_name":"2026_AstronomyAstrophysics_Napolitano.pdf","file_id":"23099","date_created":"2026-10-12T07:09:27Z"}],"article_type":"original","supplementarymaterial":"yes","date_updated":"2026-10-20T08:15:36Z","type":"journal_article","publisher":"EDP Sciences","publication_identifier":{"eissn":["1432-0746"],"issn":["0004-6361"]}},{"day":"01","language":[{"iso":"eng"}],"OA_type":"diamond","publication_status":"published","file_date_updated":"2026-10-12T07:31:23Z","department":[{"_id":"JoMa"}],"year":"2026","researchdata_availability":"yes","date_published":"2026-04-01T00:00:00Z","abstract":[{"text":"The previously inaccessible star formation tracer Paschen-Alpha (Paα) can now be spatially resolved by JWST NIRCam slitless spectroscopy in distant galaxies up to cosmic noon. In the first study of its kind, we combine JWST NGDEEP NIRISS and FRESCO NIRCam slitless spectroscopy to provide the first direct comparison of spatially resolved dust-obscured (traced by Paα) versus unobscured (traced by Hα) star formation across the main sequence. We stacked Paα and Hα emission-line maps, along with stellar continuum images at both wavelengths of 31 galaxies at 1 < z < 1.8 in three bins of stellar mass spanning 7.7 ≤ log(M*/M⊙) < 11. Surface brightness profiles were measured and equivalent width (EW) profiles computed. Increasing Paα and Hα EW profiles with galactocentric radius across all stellar masses probed provides direct evidence for the inside-out growth of galaxies both via dust-obscured and unobscured star formation for the first time. For galaxies predominantly on the main sequence (log(M*/M⊙)≥8.8), a weakly positive (0.1 ± 0.1) Paα/Hα line profile gradient as a function of radius is found at 8.8 ≤ log(M*/M⊙) < 9.9, with a negative (−0.4 ± 0.1) Paα/Hα line profile gradient as a function of radius found at the highest stellar masses of 9.9 ≤ log(M*/M⊙) < 11.0. Low-mass galaxies (7.7 ≤ log(M*/M⊙) < 8.8) with predominantly high specific star formation rates relative to the main sequence are also found to have a negative (−0.5 ± 0.1) Paα/Hα line profile gradient as a function of radius. Our results demonstrate that while inside-out growth via star formation is ubiquitous across the main sequence just after cosmic noon, centrally concentrated dust attenuation is not. Along with other recent work in the literature, our findings now motivate future studies of resolved SFR and dust attenuation profiles in large samples of individual cosmic noon galaxies across the main sequence, aimed at understanding the intrinsic scatter in spatially resolved star formation.","lang":"eng"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","month":"04","title":"A first look at a complete view of spatially resolved star formation at 1  <  z  <  1.8 with JWST NGDEEP+FRESCO slitless spectroscopy","citation":{"short":"J. Matharu, L. Shen, I. Shivaei, P.A. Oesch, C. Papovich, G. Brammer, N.A. Reddy, Y. Cheng, P. Van Dokkum, S.L. Finkelstein, N.P. Hathi, J.S. Kartaltepe, A.M. Koekemoer, J.J. Matthee, N. Pirzkal, S.M. Wilkins, M.A. Wozniak, M. Xiao, Astronomy &#38; Astrophysics 708 (2026).","ieee":"J. Matharu <i>et al.</i>, “A first look at a complete view of spatially resolved star formation at 1  &#60;  z  &#60;  1.8 with JWST NGDEEP+FRESCO slitless spectroscopy,” <i>Astronomy &#38; Astrophysics</i>, vol. 708. EDP Sciences, 2026.","apa":"Matharu, J., Shen, L., Shivaei, I., Oesch, P. A., Papovich, C., Brammer, G., … Xiao, M. (2026). A first look at a complete view of spatially resolved star formation at 1  &#60;  z  &#60;  1.8 with JWST NGDEEP+FRESCO slitless spectroscopy. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202558205\">https://doi.org/10.1051/0004-6361/202558205</a>","chicago":"Matharu, Jasleen, Lu Shen, Irene Shivaei, Pascal A. Oesch, Casey Papovich, Gabriel Brammer, Naveen A. Reddy, et al. “A First Look at a Complete View of Spatially Resolved Star Formation at 1  &#60;  z  &#60;  1.8 with JWST NGDEEP+FRESCO Slitless Spectroscopy.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2026. <a href=\"https://doi.org/10.1051/0004-6361/202558205\">https://doi.org/10.1051/0004-6361/202558205</a>.","ama":"Matharu J, Shen L, Shivaei I, et al. A first look at a complete view of spatially resolved star formation at 1  &#60;  z  &#60;  1.8 with JWST NGDEEP+FRESCO slitless spectroscopy. <i>Astronomy &#38; Astrophysics</i>. 2026;708. doi:<a href=\"https://doi.org/10.1051/0004-6361/202558205\">10.1051/0004-6361/202558205</a>","mla":"Matharu, Jasleen, et al. “A First Look at a Complete View of Spatially Resolved Star Formation at 1  &#60;  z  &#60;  1.8 with JWST NGDEEP+FRESCO Slitless Spectroscopy.” <i>Astronomy &#38; Astrophysics</i>, vol. 708, A33, EDP Sciences, 2026, doi:<a href=\"https://doi.org/10.1051/0004-6361/202558205\">10.1051/0004-6361/202558205</a>.","ista":"Matharu J, Shen L, Shivaei I, Oesch PA, Papovich C, Brammer G, Reddy NA, Cheng Y, Van Dokkum P, Finkelstein SL, Hathi NP, Kartaltepe JS, Koekemoer AM, Matthee JJ, Pirzkal N, Wilkins SM, Wozniak MA, Xiao M. 2026. A first look at a complete view of spatially resolved star formation at 1  &#60;  z  &#60;  1.8 with JWST NGDEEP+FRESCO slitless spectroscopy. Astronomy &#38; Astrophysics. 708, A33."},"author":[{"last_name":"Matharu","first_name":"Jasleen","full_name":"Matharu, Jasleen"},{"last_name":"Shen","first_name":"Lu","full_name":"Shen, Lu"},{"last_name":"Shivaei","first_name":"Irene","full_name":"Shivaei, Irene"},{"last_name":"Oesch","first_name":"Pascal A.","full_name":"Oesch, Pascal A."},{"first_name":"Casey","full_name":"Papovich, Casey","last_name":"Papovich"},{"last_name":"Brammer","first_name":"Gabriel","full_name":"Brammer, Gabriel"},{"first_name":"Naveen A.","full_name":"Reddy, Naveen A.","last_name":"Reddy"},{"last_name":"Cheng","first_name":"Yingjie","full_name":"Cheng, Yingjie"},{"first_name":"Pieter","full_name":"Van Dokkum, Pieter","last_name":"Van Dokkum"},{"last_name":"Finkelstein","full_name":"Finkelstein, Steven L.","first_name":"Steven L."},{"first_name":"Nimish P.","full_name":"Hathi, Nimish P.","last_name":"Hathi"},{"first_name":"Jeyhan S.","full_name":"Kartaltepe, Jeyhan S.","last_name":"Kartaltepe"},{"last_name":"Koekemoer","first_name":"Anton M.","full_name":"Koekemoer, Anton M."},{"last_name":"Matthee","orcid":"0000-0003-2871-127X","id":"7439a258-f3c0-11ec-9501-9df22fe06720","full_name":"Matthee, Jorryt J","first_name":"Jorryt J"},{"full_name":"Pirzkal, Nor","first_name":"Nor","last_name":"Pirzkal"},{"last_name":"Wilkins","first_name":"Stephen M.","full_name":"Wilkins, Stephen M."},{"last_name":"Wozniak","full_name":"Wozniak, Michael A.","first_name":"Michael A."},{"last_name":"Xiao","full_name":"Xiao, Mengyuan","first_name":"Mengyuan"}],"_id":"23048","quality_controlled":"1","status":"public","doi":"10.1051/0004-6361/202558205","intvolume":"       708","oa_version":"Published Version","DOAJ_listed":"1","ddc":["520"],"fulldoi":"https://doi.org/10.1051/0004-6361/202558205","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_number":"A33","external_id":{"arxiv":["2511.15792"]},"arxiv":1,"article_processing_charge":"No","OA_place":"publisher","PlanS_conform":"1","scopus_import":"1","oa":1,"date_created":"2026-10-04T22:01:55Z","volume":708,"has_accepted_license":"1","acknowledgement":"JM is grateful to the Max Planck Society for the MPIA Prize Fellowship and to the Cosmic Dawn Center for the DAWN Fellowship. This work is based on observations made with the NASA/ESA/CSA James Webb Space Telescope. The raw data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with JWST Cycle 1 GO programs #1895 and #2079. Support for both programs was provided by NASA through a grant from the Space Telescope Science Institute, which is operated by the Associations of Universities for Research in Astronomy, Incorporated, under NASA contract NAS5-26555. The Cosmic Dawn Center (DAWN) is funded by the Danish National Research Foundation under grant DNRF140. This work has received funding from the Swiss State Secretariat for Education, Research and Innovation (SERI) under contract number MB22.00072, as well as from the Swiss National Science Foundation (SNSF) through project grant 200020_207349. This work benefited from support from the George P. and Cynthia Woods Mitchell Institute for Fundamental Physics and Astronomy at Texas A&M University. CP thanks Marsha and Ralph Schilling for generous support of this research.","publication":"Astronomy & Astrophysics","das_tickbox":"0","publisher":"EDP Sciences","type":"journal_article","publication_identifier":{"issn":["0004-6361"],"eissn":["1432-0746"]},"file":[{"date_created":"2026-10-12T07:31:23Z","file_id":"23101","file_name":"2026_AstronomyAstrophysics_Matharu.pdf","date_updated":"2026-10-12T07:31:23Z","checksum":"875d217ea15192fa1208f3db34a7fad6","relation":"main_file","creator":"dernst","success":1,"access_level":"open_access","file_size":587642,"content_type":"application/pdf"}],"article_type":"original","supplementarymaterial":"no","date_updated":"2026-10-20T08:16:24Z"},{"DOAJ_listed":"1","oa_version":"Published Version","author":[{"first_name":"S.","full_name":"Hekker, S.","last_name":"Hekker"},{"last_name":"Elsworth","first_name":"Y.","full_name":"Elsworth, Y."},{"last_name":"Basu","full_name":"Basu, S.","first_name":"S."},{"last_name":"Ahlborn","full_name":"Ahlborn, F.","first_name":"F."},{"last_name":"Ball","full_name":"Ball, W. H.","first_name":"W. H."},{"last_name":"Bellinger","full_name":"Bellinger, E. P.","first_name":"E. P."},{"first_name":"Lynn","full_name":"Buchele, Lynn","id":"158c74c1-eed5-11ef-8c05-e45f52925cdc","last_name":"Buchele"},{"last_name":"Espinoza-Rojas","full_name":"Espinoza-Rojas, F.","first_name":"F."}],"_id":"23045","status":"public","quality_controlled":"1","intvolume":"       709","doi":"10.1051/0004-6361/202557690","fulldoi":"https://doi.org/10.1051/0004-6361/202557690","ddc":["520"],"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_number":"A84","external_id":{"arxiv":["2603.16597"]},"PlanS_conform":"1","scopus_import":"1","arxiv":1,"article_processing_charge":"No","OA_place":"publisher","OA_type":"diamond","language":[{"iso":"eng"}],"day":"01","department":[{"_id":"LiBu"}],"file_date_updated":"2026-10-07T12:35:39Z","publication_status":"published","year":"2026","citation":{"mla":"Hekker, S., et al. “The Sensitivity and Behaviour of the Curvature in the Échelle Diagram of Red-Giant Stars.” <i>Astronomy &#38; Astrophysics</i>, vol. 709, A84, EDP Sciences, 2026, doi:<a href=\"https://doi.org/10.1051/0004-6361/202557690\">10.1051/0004-6361/202557690</a>.","ista":"Hekker S, Elsworth Y, Basu S, Ahlborn F, Ball WH, Bellinger EP, Buchele L, Espinoza-Rojas F. 2026. The sensitivity and behaviour of the curvature in the échelle diagram of red-giant stars. Astronomy &#38; Astrophysics. 709, A84.","chicago":"Hekker, S., Y. Elsworth, S. Basu, F. Ahlborn, W. H. Ball, E. P. Bellinger, Lynn Buchele, and F. Espinoza-Rojas. “The Sensitivity and Behaviour of the Curvature in the Échelle Diagram of Red-Giant Stars.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2026. <a href=\"https://doi.org/10.1051/0004-6361/202557690\">https://doi.org/10.1051/0004-6361/202557690</a>.","ama":"Hekker S, Elsworth Y, Basu S, et al. The sensitivity and behaviour of the curvature in the échelle diagram of red-giant stars. <i>Astronomy &#38; Astrophysics</i>. 2026;709. doi:<a href=\"https://doi.org/10.1051/0004-6361/202557690\">10.1051/0004-6361/202557690</a>","apa":"Hekker, S., Elsworth, Y., Basu, S., Ahlborn, F., Ball, W. H., Bellinger, E. P., … Espinoza-Rojas, F. (2026). The sensitivity and behaviour of the curvature in the échelle diagram of red-giant stars. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202557690\">https://doi.org/10.1051/0004-6361/202557690</a>","ieee":"S. Hekker <i>et al.</i>, “The sensitivity and behaviour of the curvature in the échelle diagram of red-giant stars,” <i>Astronomy &#38; Astrophysics</i>, vol. 709. EDP Sciences, 2026.","short":"S. Hekker, Y. Elsworth, S. Basu, F. Ahlborn, W.H. Ball, E.P. Bellinger, L. Buchele, F. Espinoza-Rojas, Astronomy &#38; Astrophysics 709 (2026)."},"title":"The sensitivity and behaviour of the curvature in the échelle diagram of red-giant stars","month":"05","abstract":[{"text":"Context. In the convective envelopes of relatively cool (surface temperature ≲6700 K) stars, oscillations are excited by turbulent convection. In these so-called solar-like oscillators, radial oscillation modes appear at nearly equally spaced frequencies. This spacing is referred to as the ‘large-frequency separation’. Deviations from equally spaced frequencies are a result of the internal structure of a star being different from a sphere of ideal gas at constant temperature. Hence, these deviations provide information on the internal structure of the star.\r\n\r\nAims. In this work, we investigate the second-order (quadratic) deviation from uniform spacing, referred to as curvature. We aim to provide homogeneous values for observed red-giant stars, understand differences between the results from observations and predictions from stellar models, and reveal the connection between curvature and stellar structure.\r\n\r\nMethods. We used Kepler data of red-giant stars and computed the curvature for several thousand stars. We compared these to the curvature derived from MESA models. We subsequently investigated the trends and differences between results from observations and models. Finally, we computed sensitivity kernels to identify the stellar region(s) to which the curvature is most sensitive and performed a glitch analysis.\r\n\r\nResults. We found that the curvature is sensitive to evolutionary phase and mass. Interestingly, the observed values and values from models show some discrepancies. Including the surface effect in the model frequencies reduces the discrepancies, though it introduces a frequency-dependent over- or under-estimation of the curvature from the models compared to the observations. From the kernels, we confirmed that the curvature is mostly sensitive to the near-surface layers of the star. The glitch analysis shows that in theory this provides information on the location and strength of the He I and H I ionisation layers.\r\n\r\nConclusions. The curvature provides a probe into the near-surface structure of the star. The deviations between the curvature derived from observations and models call for improvements in the near-surface layers of stellar models.","lang":"eng"}],"date_published":"2026-05-01T00:00:00Z","researchdata_availability":"no","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"EDP Sciences","type":"journal_article","publication_identifier":{"issn":["0004-6361"],"eissn":["1432-0746"]},"article_type":"original","file":[{"creator":"dernst","relation":"main_file","checksum":"6f5d496ee876c8ff4bce6924be2cad19","content_type":"application/pdf","file_size":13650005,"access_level":"open_access","success":1,"date_created":"2026-10-07T12:35:39Z","date_updated":"2026-10-07T12:35:39Z","file_id":"23077","file_name":"2026_AstronomyAstrophysics_Hekker.pdf"}],"date_updated":"2026-10-20T08:14:24Z","supplementarymaterial":"yes","oa":1,"date_created":"2026-10-04T22:01:54Z","acknowledgement":"We thank the referee and editor for their comments\r\nand work, which improved the manuscript significantly. We acknowledge funding from the ERC Consolidator Grant ‘DipolarSound’ (grant agreement #\r\n101000296). SB is partially supported by NSF grant AST-2205026. YE acknowledges funding from the Science and Technology Facilities Council (STFC)","has_accepted_license":"1","das_tickbox":"0","publication":"Astronomy & Astrophysics","volume":709},{"ddc":["520"],"fulldoi":"https://doi.org/10.1051/0004-6361/202558428","_id":"23047","status":"public","quality_controlled":"1","author":[{"first_name":"Armand","full_name":"Leclerc, Armand","id":"2a1fb1fc-f373-11ef-901a-87cee43a1217","last_name":"Leclerc"},{"last_name":"Laibe","first_name":"Guillaume","full_name":"Laibe, Guillaume"},{"last_name":"Lynch","first_name":"Elliot","full_name":"Lynch, Elliot"},{"last_name":"Perez","full_name":"Perez, Nicolas","first_name":"Nicolas"}],"intvolume":"       708","doi":"10.1051/0004-6361/202558428","DOAJ_listed":"1","oa_version":"Published Version","corr_author":"1","arxiv":1,"OA_place":"publisher","article_processing_charge":"No","PlanS_conform":"1","scopus_import":"1","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_number":"A355","external_id":{"arxiv":["2512.05737"]},"publication_status":"published","file_date_updated":"2026-10-07T12:13:55Z","department":[{"_id":"LiBu"}],"project":[{"_id":"914d8549-16d5-11f0-9cad-bbe6324c93a9","name":"Unveiling the mysteries of stellar dynamics: a pioneering journey in magnetoasteroseismology","grant_number":"101165631"}],"language":[{"iso":"eng"}],"day":"01","OA_type":"diamond","researchdata_availability":"no","abstract":[{"lang":"eng","text":"Aims. We investigate signatures of pressure extrema on global oscillations in discs.\r\n\r\nMethods. We used the framework of wave topology to establish a generalised local dispersion relation that includes pressure gradients. We highlight the influence of a previously unrecognised epicyclic–acoustic frequency, and we derive an analytical criterion for the existence of a branch of modes transiting between the inertial and the pressure bands, known as topological modes.\r\n\r\nResults. We find that pressure extrema consist of wave guides in which such topological modes propagate. The fundamental mode trapped at a pressure bump can propagate at any frequency, allowing it to resonate with any temporal forcing. Conversely, the fundamental mode associated with a pressure dip propagates at any vertical phase velocity. These specific features make them attractive candidates for future discoseismology."}],"date_published":"2026-04-01T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","month":"04","title":"Radial modes of pressure bumps and dips in astrophysical discs","citation":{"ama":"Leclerc A, Laibe G, Lynch E, Perez N. Radial modes of pressure bumps and dips in astrophysical discs. <i>Astronomy &#38; Astrophysics</i>. 2026;708. doi:<a href=\"https://doi.org/10.1051/0004-6361/202558428\">10.1051/0004-6361/202558428</a>","chicago":"Leclerc, Armand, Guillaume Laibe, Elliot Lynch, and Nicolas Perez. “Radial Modes of Pressure Bumps and Dips in Astrophysical Discs.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2026. <a href=\"https://doi.org/10.1051/0004-6361/202558428\">https://doi.org/10.1051/0004-6361/202558428</a>.","short":"A. Leclerc, G. Laibe, E. Lynch, N. Perez, Astronomy &#38; Astrophysics 708 (2026).","ieee":"A. Leclerc, G. Laibe, E. Lynch, and N. Perez, “Radial modes of pressure bumps and dips in astrophysical discs,” <i>Astronomy &#38; Astrophysics</i>, vol. 708. EDP Sciences, 2026.","apa":"Leclerc, A., Laibe, G., Lynch, E., &#38; Perez, N. (2026). Radial modes of pressure bumps and dips in astrophysical discs. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202558428\">https://doi.org/10.1051/0004-6361/202558428</a>","ista":"Leclerc A, Laibe G, Lynch E, Perez N. 2026. Radial modes of pressure bumps and dips in astrophysical discs. Astronomy &#38; Astrophysics. 708, A355.","mla":"Leclerc, Armand, et al. “Radial Modes of Pressure Bumps and Dips in Astrophysical Discs.” <i>Astronomy &#38; Astrophysics</i>, vol. 708, A355, EDP Sciences, 2026, doi:<a href=\"https://doi.org/10.1051/0004-6361/202558428\">10.1051/0004-6361/202558428</a>."},"year":"2026","publication_identifier":{"eissn":["1432-0746"],"issn":["0004-6361"]},"keyword":["accretion","accretion disks","hydrodynamics","instabilities","waves","protoplanetary disks"],"publisher":"EDP Sciences","type":"journal_article","supplementarymaterial":"yes","date_updated":"2026-10-20T08:14:41Z","file":[{"content_type":"application/pdf","file_size":10533299,"success":1,"access_level":"open_access","relation":"main_file","creator":"dernst","checksum":"868c1be53a4f3e0cf2852a723fcacd08","date_updated":"2026-10-07T12:13:55Z","file_name":"2026_AstronomyAstrophysics_Leclerc.pdf","file_id":"23075","date_created":"2026-10-07T12:13:55Z"}],"article_type":"original","oa":1,"dataavailabilitystatement":"The scripts written and used for numerical calculations\r\nare accessible at https://github.com/ArmandLeclerc/\r\nradialStratifDisc.","volume":708,"has_accepted_license":"1","acknowledgement":"AL was funded by Contrat Doctoral Spécifique Normaliens during this work. GL, EL and NP acknowledge funding from\r\nERC CoG project PODCAST No 864965. AL acknowledges funding\r\nfrom ERC StG project Calcifer No 101165631. We used Mathematica\r\n(Wolfram Research Inc, 2024).\r\n","das_tickbox":"1","publication":"Astronomy & Astrophysics","date_created":"2026-10-04T22:01:54Z"},{"fulldoi":"https://doi.org/10.15479/AT-ISTA-22744","supervisor":[{"last_name":"Schur","orcid":"0000-0003-4790-8078","id":"48AD8942-F248-11E8-B48F-1D18A9856A87","full_name":"Schur, Florian KM","first_name":"Florian KM"},{"full_name":"Sixt, Michael K","first_name":"Michael K","last_name":"Sixt","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6620-9179"}],"ddc":["570"],"corr_author":"1","oa_version":"None","doi":"10.15479/AT-ISTA-22744","status":"public","_id":"22744","author":[{"last_name":"Javoor","orcid":"0000-0003-2311-2112","id":"305ab18b-dc7d-11ea-9b2f-b58195228ea2","full_name":"Javoor, Manjunath","first_name":"Manjunath"}],"OA_place":"publisher","article_processing_charge":"No","tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"acknowledged_ssus":[{"_id":"Bio"},{"_id":"EM-Fac"},{"_id":"ScienComp"},{"_id":"LifeSc"}],"department":[{"_id":"GradSch"},{"_id":"FlSc"},{"_id":"MiSi"}],"file_date_updated":"2026-08-27T12:48:42Z","publication_status":"published","day":"21","language":[{"iso":"eng"}],"project":[{"grant_number":"101076260","name":"A molecular atlas of Actin filament IDentities in the cell motility machinery","_id":"bd980d18-d553-11ed-ba76-ceaa645c97eb"},{"_id":"bd91e723-d553-11ed-ba76-fe7eeb2185fd","name":"Pushing from within: Control of cell shape, integrity and motility by cytoskeletal pushing forces","grant_number":"101071793"}],"citation":{"ama":"Javoor M. Large-scale imaging of cellular actin networks at single filament resolution using montage cryo-electron tomography. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22744\">10.15479/AT-ISTA-22744</a>","chicago":"Javoor, Manjunath. “Large-Scale Imaging of Cellular Actin Networks at Single Filament Resolution Using Montage Cryo-Electron Tomography.” Institute of Science and Technology Austria , 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-22744\">https://doi.org/10.15479/AT-ISTA-22744</a>.","short":"M. Javoor, Large-Scale Imaging of Cellular Actin Networks at Single Filament Resolution Using Montage Cryo-Electron Tomography, Institute of Science and Technology Austria , 2026.","apa":"Javoor, M. (2026). <i>Large-scale imaging of cellular actin networks at single filament resolution using montage cryo-electron tomography</i>. Institute of Science and Technology Austria . <a href=\"https://doi.org/10.15479/AT-ISTA-22744\">https://doi.org/10.15479/AT-ISTA-22744</a>","ieee":"M. Javoor, “Large-scale imaging of cellular actin networks at single filament resolution using montage cryo-electron tomography,” Institute of Science and Technology Austria , 2026.","mla":"Javoor, Manjunath. <i>Large-Scale Imaging of Cellular Actin Networks at Single Filament Resolution Using Montage Cryo-Electron Tomography</i>. Institute of Science and Technology Austria , 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22744\">10.15479/AT-ISTA-22744</a>.","ista":"Javoor M. 2026. Large-scale imaging of cellular actin networks at single filament resolution using montage cryo-electron tomography. Institute of Science and Technology Austria ."},"title":"Large-scale imaging of cellular actin networks at single filament resolution using montage cryo-electron tomography","month":"08","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","date_published":"2026-08-21T00:00:00Z","year":"2026","doi_confirm":"1","publication_identifier":{"issn":["2663-337X"],"isbn":["978-3-99078-090-9 "]},"degree_awarded":"PhD","type":"dissertation","publisher":"Institute of Science and Technology Austria ","keyword":["Actin cytoskeleton","Cell migration","cryo-electron tomography"],"page":"121","related_material":{"record":[{"id":"12334","status":"public","relation":"part_of_dissertation"},{"status":"public","id":"21762","relation":"part_of_dissertation"},{"relation":"part_of_dissertation","id":"12421","status":"public"},{"id":"19795","status":"public","relation":"part_of_dissertation"}]},"date_updated":"2026-10-20T08:55:33Z","license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","file":[{"access_level":"closed","file_size":27430796,"content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","checksum":"f9c2847df9f1ac5a3d60c06b3b81a450","creator":"mjavoor","relation":"source_file","file_name":"2026_Javoor_Manjunath_Thesis.docx","file_id":"22767","date_updated":"2026-08-27T12:48:42Z","date_created":"2026-08-26T12:02:47Z"},{"date_updated":"2026-08-26T12:02:46Z","embargo":"2027-08-21","file_id":"22768","file_name":"2026_Javoor_Manjunath_Thesis.pdf","embargo_to":"open_access","date_created":"2026-08-26T12:02:46Z","file_size":19489230,"content_type":"application/pdf","access_level":"closed","relation":"main_file","creator":"mjavoor","checksum":"8e9b4c0fcafbccf5c3796eacc9134a08"}],"OA_embargo":"12","has_accepted_license":"1","acknowledgement":"This work was supported by the ERC StG grant ActinID (PRA01221F1049A) awarded to Florian\r\nSchur, the ERC-SyG grant Pushing from within (P01071793) awarded to Michael Sixt, and by ISTA.\r\nI would like to thank the Scientific Service Units at ISTA for their essential support throughout\r\nthis work. In particular, I am grateful to the Electron Microscopy Facility, Imaging and Optics\r\nFacility, Zebrafish Facility, Scientific Computing Facility, and Lab Support Facility for their services,\r\nand technical support, all of which were important for the successful completion of this project.","alternative_title":["ISTA Thesis"],"date_created":"2026-08-21T09:11:04Z"},{"language":[{"iso":"eng"}],"day":"24","OA_type":"gold","publication_status":"published","department":[{"_id":"AmDo"}],"file_date_updated":"2026-05-04T11:58:51Z","year":"2026","date_published":"2026-02-24T00:00:00Z","abstract":[{"lang":"eng","text":"The paraventricular hypothalamus (PVH) controls behavioral and physiologic processes, including appetite, social behavior, autonomic outflow, and pituitary hormone secretion. However, molecular markers for centrally projecting PVH neuron populations remain largely undefined, and a complete census of PVH cell types has not been established. Therefore, we performed extensive single-cell/nucleus RNA sequencing to catalog PVH neuron subtypes and multiplexed error-robust fluorescence in situ hybridization (MERFISH) to map them spatially. Our spatial transcriptomic atlas resolves 26 Sim1+ and 29 GABAergic neuron populations from the PVH and surrounding areas. Additionally, projection-based profiling identified neurons that project to the parabrachial region (PB) and spinal cord, helping to determine PVH populations that regulate satiety and sympathetic nervous system activity, respectively. Notably, activation of PB-projecting PVH neurons expressing Brs3 reduces food intake, and silencing them causes obesity. Together, this atlas contributes high-resolution PVH spatial and circuit-based gene expression profiles, representing a valuable resource for the field of homeostasis."}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","month":"02","citation":{"ieee":"Y. Li <i>et al.</i>, “A spatial and projection-based transcriptomic atlas of paraventricular hypothalamic cell types,” <i>Cell Reports</i>, vol. 45, no. 2. Cell Press, 2026.","apa":"Li, Y., Butler, T. C., Nardone, S., Jacobs, C. L., Douglass, A. M., Madara, J. C., … Resch, J. M. (2026). A spatial and projection-based transcriptomic atlas of paraventricular hypothalamic cell types. <i>Cell Reports</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.celrep.2025.116904\">https://doi.org/10.1016/j.celrep.2025.116904</a>","short":"Y. Li, T.C. Butler, S. Nardone, C.L. Jacobs, A.M. Douglass, J.C. Madara, M.C. McDonough, J. Tao, E.D. Lowenstein, L. Wang, D. Pant, S.J. Walker, A. Wang, H. Srinivasan, Z. Yang, J.N. Campbell, L.T. Tsai, B.B. Lowell, J.M. Resch, Cell Reports 45 (2026).","ama":"Li Y, Butler TC, Nardone S, et al. A spatial and projection-based transcriptomic atlas of paraventricular hypothalamic cell types. <i>Cell Reports</i>. 2026;45(2). doi:<a href=\"https://doi.org/10.1016/j.celrep.2025.116904\">10.1016/j.celrep.2025.116904</a>","chicago":"Li, Yuxi, Trevor C. Butler, Stefano Nardone, Christopher L. Jacobs, Amelia M. Douglass, Joseph C. Madara, Miriam C. McDonough, et al. “A Spatial and Projection-Based Transcriptomic Atlas of Paraventricular Hypothalamic Cell Types.” <i>Cell Reports</i>. Cell Press, 2026. <a href=\"https://doi.org/10.1016/j.celrep.2025.116904\">https://doi.org/10.1016/j.celrep.2025.116904</a>.","ista":"Li Y, Butler TC, Nardone S, Jacobs CL, Douglass AM, Madara JC, McDonough MC, Tao J, Lowenstein ED, Wang L, Pant D, Walker SJ, Wang A, Srinivasan H, Yang Z, Campbell JN, Tsai LT, Lowell BB, Resch JM. 2026. A spatial and projection-based transcriptomic atlas of paraventricular hypothalamic cell types. Cell Reports. 45(2), 116904.","mla":"Li, Yuxi, et al. “A Spatial and Projection-Based Transcriptomic Atlas of Paraventricular Hypothalamic Cell Types.” <i>Cell Reports</i>, vol. 45, no. 2, 116904, Cell Press, 2026, doi:<a href=\"https://doi.org/10.1016/j.celrep.2025.116904\">10.1016/j.celrep.2025.116904</a>."},"title":"A spatial and projection-based transcriptomic atlas of paraventricular hypothalamic cell types","_id":"21744","quality_controlled":"1","author":[{"last_name":"Li","first_name":"Yuxi","full_name":"Li, Yuxi"},{"last_name":"Butler","full_name":"Butler, Trevor C.","first_name":"Trevor C."},{"first_name":"Stefano","full_name":"Nardone, Stefano","last_name":"Nardone"},{"full_name":"Jacobs, Christopher L.","first_name":"Christopher L.","last_name":"Jacobs"},{"last_name":"Douglass","id":"de5f6fda-80fb-11ef-996f-a8c4ecd8e289","orcid":"0000-0001-5398-6473","full_name":"Douglass, Amelia May Barnett","first_name":"Amelia May Barnett"},{"full_name":"Madara, Joseph C.","first_name":"Joseph C.","last_name":"Madara"},{"first_name":"Miriam C.","full_name":"McDonough, Miriam C.","last_name":"McDonough"},{"first_name":"Jenkang","full_name":"Tao, Jenkang","last_name":"Tao"},{"last_name":"Lowenstein","full_name":"Lowenstein, Elijah D.","first_name":"Elijah D."},{"last_name":"Wang","first_name":"Luhong","full_name":"Wang, Luhong"},{"full_name":"Pant, Deepti","first_name":"Deepti","last_name":"Pant"},{"first_name":"Samuel J.","full_name":"Walker, Samuel J.","last_name":"Walker"},{"full_name":"Wang, Annette","first_name":"Annette","last_name":"Wang"},{"last_name":"Srinivasan","first_name":"Harini","full_name":"Srinivasan, Harini"},{"last_name":"Yang","full_name":"Yang, Zongfang","first_name":"Zongfang"},{"full_name":"Campbell, John N.","first_name":"John N.","last_name":"Campbell"},{"last_name":"Tsai","first_name":"Linus T.","full_name":"Tsai, Linus T."},{"full_name":"Lowell, Bradford B.","first_name":"Bradford B.","last_name":"Lowell"},{"full_name":"Resch, Jon M.","first_name":"Jon M.","last_name":"Resch"}],"status":"public","doi":"10.1016/j.celrep.2025.116904","intvolume":"        45","oa_version":"Published Version","DOAJ_listed":"1","ddc":["570"],"fulldoi":"https://doi.org/10.1016/j.celrep.2025.116904","article_number":"116904","tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"external_id":{"pmid":["41581146"]},"article_processing_charge":"Yes","OA_place":"publisher","scopus_import":"1","oa":1,"issue":"2","date_created":"2026-04-16T13:51:29Z","volume":45,"acknowledgement":"We would like to thank Drs. Mark Andermann, Joel Geerling, and Clifford\r\nSaper, as well as the Lowell, Tsai, and Resch laboratories for helpful discussions;\r\nAlysia Berns, Jia Yu, and Yanfang Li for technical support; the BNORC\r\nFunctional Genomics and Bioinformatics Core (P30DK046200) and the Iowa\r\nInstitute for Human Genetics Genomics Division (IIHG, RRID: SCR_023422)\r\nfor helpful discussions and technical assistance with sc/snRNA-seq; Zachary\r\nNiziolek and the Bauer Core Facility at Harvard University, the BIDMC Flow Cytometry\r\nCore, and Heath Vignes, Michael Shey, and Thomas Kaufman of the\r\nFlow Cytometry Facility at the University of Iowa Carver College of Medicine\r\nfor helpful discussions and technical support; the ICCB-Longwood Screening\r\nFacility of Harvard Medical School for assistance with the snRNA-seq\r\nexperiments; Dr. Sayak Mitter and Vizgen support for technical assistance\r\nwith the MERSCOPE platform; and Mara Jendro and Li-Chun (Queena) Lin\r\nfor their assistance with MERSCOPE experiments within the Iowa\r\nNeuroBank Core in the Iowa Neuroscience Institute at the University of Iowa\r\nCarver College of Medicine. This research was funded by the following NIH\r\ngrants to L.T.T.: R01DK128406; to B.B.L.: R01DK075632, R01DK134427,\r\nand R01DK096010; to J.M.R.: R00HL144923 and R01NS141072; and to M.C.M.: F31HL170784; T.C.B. and M.C.M. were supported by a pharmacological\r\nsciences predoctoral training grant T32GM144636. Additional funding\r\nto J.M.R. came from the American Heart Association (AHA 935362), a University\r\nof Iowa Fraternal Order of Eagles Diabetes Research Center Pilot and\r\nFeasibility Catalyst Grant, and an Iowa Neuroscience Institute Early Stage\r\nInvestigator award from the Carver Trust. Y.L. was supported by a predoctoral\r\nfellowship from the American Heart Association (AHA 25PRE1372983). A.M.D.\r\nwas supported by a postdoctoral fellowship from the Charles A. King Trust.","has_accepted_license":"1","publication":"Cell Reports","publisher":"Cell Press","type":"journal_article","pmid":1,"publication_identifier":{"eissn":["2211-1247"],"issn":["2639-1856"]},"file":[{"date_updated":"2026-05-04T11:58:51Z","file_id":"21793","file_name":"2026_CellReports_Li.pdf","date_created":"2026-05-04T11:58:51Z","file_size":38532865,"content_type":"application/pdf","success":1,"access_level":"open_access","relation":"main_file","creator":"dernst","checksum":"82098dd9d0ca609119f9f2c6beb4fc1e"}],"article_type":"original","date_updated":"2026-10-20T08:58:10Z"},{"external_id":{"pmid":["41831441"]},"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_processing_charge":"Yes (via OA deal)","OA_place":"publisher","PlanS_conform":"1","doi":"10.1016/j.cub.2026.02.023","intvolume":"        36","status":"public","_id":"21490","quality_controlled":"1","author":[{"first_name":"Mingyue","full_name":"Li, Mingyue","id":"01f96916-0235-11eb-9379-a323192643b7","last_name":"Li"},{"full_name":"Rydza, Nikola","first_name":"Nikola","last_name":"Rydza"},{"full_name":"Mazur, Ewa","first_name":"Ewa","last_name":"Mazur"},{"full_name":"Molnar, Gergely","first_name":"Gergely","last_name":"Molnar","id":"34F1AF46-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Nodzyński","full_name":"Nodzyński, Tomasz","first_name":"Tomasz"},{"full_name":"Friml, Jiří","first_name":"Jiří","last_name":"Friml","id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596"}],"corr_author":"1","oa_version":"Published Version","ddc":["580"],"fulldoi":"https://doi.org/10.1016/j.cub.2026.02.023","year":"2026","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2026-03-23T00:00:00Z","abstract":[{"text":"Auxin canalization is a self-organizing process that governs the flexible formation of vasculature by reinforcing the formation of auxin transport channels. A key prerequisite is the feedback between auxin signaling and directional auxin transport, mediated by PIN transporters. Despite the developmental importance of canalization, the molecular components linking auxin perception to the regulation of PIN auxin transporters remain poorly understood. Here, we identify TOW, a novel and essential component of auxin canalization that links intracellular auxin signaling with cell surface auxin perception. TOW is regulated downstream of TIR1/AFB-Aux/IAA-WRKY23 transcriptional auxin signaling. tow mutants exhibit defects in regeneration and de novo vasculature formation, along with impaired formation of polarized, PIN-expressing auxin channels. At the subcellular level, these mutants display disrupted auxin-induced PIN polarization and altered PIN endocytic trafficking dynamics. TOW localizes predominantly to the plasma membrane, where it interacts with receptor-like kinases involved in auxin canalization, including the TMK1 auxin co-receptor and the CAMEL-CANAR complex. TOW promotes PIN interaction with these kinases and stabilizes PINs at the cell surface. Together, our findings identify TOW as a molecular link between intracellular and cell surface auxin signaling mechanisms that converge on PIN trafficking and polarity, providing new insights into how auxin signaling regulates directional auxin transport for the self-organizing formation of vasculature during flexible plant development.","lang":"eng"}],"title":"Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin canalization","citation":{"mla":"Li, Mingyue, et al. “Receptor-like-Kinase-Interacting Protein TOW Stabilizes PIN Transporters for Auxin Canalization.” <i>Current Biology</i>, vol. 36, no. 6, Cell Press, 2026, p. 1468–1480.e6, doi:<a href=\"https://doi.org/10.1016/j.cub.2026.02.023\">10.1016/j.cub.2026.02.023</a>.","ista":"Li M, Rydza N, Mazur E, Molnar G, Nodzyński T, Friml J. 2026. Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin canalization. Current Biology. 36(6), 1468–1480.e6.","chicago":"Li, Mingyue, Nikola Rydza, Ewa Mazur, Gergely Molnar, Tomasz Nodzyński, and Jiří Friml. “Receptor-like-Kinase-Interacting Protein TOW Stabilizes PIN Transporters for Auxin Canalization.” <i>Current Biology</i>. Cell Press, 2026. <a href=\"https://doi.org/10.1016/j.cub.2026.02.023\">https://doi.org/10.1016/j.cub.2026.02.023</a>.","ama":"Li M, Rydza N, Mazur E, Molnar G, Nodzyński T, Friml J. Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin canalization. <i>Current Biology</i>. 2026;36(6):1468-1480.e6. doi:<a href=\"https://doi.org/10.1016/j.cub.2026.02.023\">10.1016/j.cub.2026.02.023</a>","apa":"Li, M., Rydza, N., Mazur, E., Molnar, G., Nodzyński, T., &#38; Friml, J. (2026). Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin canalization. <i>Current Biology</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.cub.2026.02.023\">https://doi.org/10.1016/j.cub.2026.02.023</a>","short":"M. Li, N. Rydza, E. Mazur, G. Molnar, T. Nodzyński, J. Friml, Current Biology 36 (2026) 1468–1480.e6.","ieee":"M. Li, N. Rydza, E. Mazur, G. Molnar, T. Nodzyński, and J. Friml, “Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin canalization,” <i>Current Biology</i>, vol. 36, no. 6. Cell Press, p. 1468–1480.e6, 2026."},"month":"03","language":[{"iso":"eng"}],"day":"23","project":[{"grant_number":"101142681","name":"Cyclic nucleotides as second messengers in plants","_id":"8f347782-16d5-11f0-9cad-8c19706ee739"},{"grant_number":"E271","_id":"bd906599-d553-11ed-ba76-abf8547645d7","name":"Identification of a novel regulator in auxin canalization"}],"OA_type":"hybrid","publication_status":"published","acknowledged_ssus":[{"_id":"MassSpec"},{"_id":"Bio"},{"_id":"LifeSc"}],"department":[{"_id":"JiFr"}],"file_date_updated":"2026-03-24T08:34:37Z","file":[{"access_level":"open_access","success":1,"file_size":12986894,"content_type":"application/pdf","checksum":"fe6c41fdab58a55df5f2a5860c02acdc","creator":"dernst","relation":"main_file","file_id":"21496","file_name":"2026_CurrentBiology_Li.pdf","date_updated":"2026-03-24T08:34:37Z","date_created":"2026-03-24T08:34:37Z"}],"article_type":"original","date_updated":"2026-10-20T08:57:40Z","page":"1468-1480.e6","type":"journal_article","publisher":"Cell Press","pmid":1,"publication_identifier":{"issn":["0960-9822"]},"date_created":"2026-03-23T15:11:16Z","issue":"6","volume":36,"publication":"Current Biology","acknowledgement":"We thank Dr. Z. Ge (ISTA) for providing vectors for the CRISPR-Cas9 system, Dr. Armel Nicolas and Dr. Bella Bruszel for phosphoproteomic analysis, Prof. Michael Wrzaczek (Czech Academy of Sciences, Czechia) for valuable suggestions, and Prof. Maciek Adamowski (University of Gdańsk) for technical assistance. We also acknowledge the support of the Mass Spectrometry and Proteomics Facility, the Imaging & Optics Facility, and the Lab Support Facility at the Institute of Science and Technology Austria. This research was supported by the Scientific Service Units (SSU) of ISTA, utilizing resources provided by the Imaging & Optics Facility (IOF) and the Lab Support Facility (LSF). The work conducted by the Friml group was funded by the European Research Council (ERC) under grant agreement no. 101142681 (CYNIPS) and by the Austrian Science Fund (FWF) under project ESP271. We acknowledge the core facility CELLIM supported by MEYS CR (LM2023050 Czech-BioImaging) and the Plant Sciences Core Facility of CEITEC Masaryk University. E.M. received support from the National Science Centre (NCN), Poland, through the OPUS call within the Weave programme (grant no. 2021/43/I/NZ1/01835). T.N. received support from TowArds Next GENeration Crops, reg. no. CZ.02.01.01/00/22_008/0004581 of the ERDF Programme Johannes Amos Comenius.","has_accepted_license":"1","oa":1}]
