[{"date_updated":"2025-09-29T12:01:08Z","month":"10","year":"2014","publisher":"Springer","volume":14,"fulldoi":"https://doi.org/10.1007/s10208-014-9205-0","main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/1209.0285"}],"author":[{"first_name":"Shaowei","last_name":"Lin","full_name":"Lin, Shaowei"},{"full_name":"Uhler, Caroline","last_name":"Uhler","orcid":"0000-0002-7008-0216","id":"49ADD78E-F248-11E8-B48F-1D18A9856A87","first_name":"Caroline"},{"full_name":"Sturmfels, Bernd","last_name":"Sturmfels","first_name":"Bernd"},{"full_name":"Bühlmann, Peter","first_name":"Peter","last_name":"Bühlmann"}],"page":"1079 - 1116","doi":"10.1007/s10208-014-9205-0","article_processing_charge":"No","abstract":[{"text":"An asymptotic theory is developed for computing volumes of regions in the parameter space of a directed Gaussian graphical model that are obtained by bounding partial correlations. We study these volumes using the method of real log canonical thresholds from algebraic geometry. Our analysis involves the computation of the singular loci of correlation hypersurfaces. Statistical applications include the strong-faithfulness assumption for the PC algorithm and the quantification of confounder bias in causal inference. A detailed analysis is presented for trees, bow ties, tripartite graphs, and complete graphs.\r\n","lang":"eng"}],"department":[{"_id":"CaUh"}],"language":[{"iso":"eng"}],"external_id":{"isi":["000342283800007"],"arxiv":["1209.0285"]},"publist_id":"5063","intvolume":"        14","oa":1,"issue":"5","_id":"2013","acknowledgement":"This work was supported in part by the US National Science Foundation (DMS-0968882) and the Defense Advanced Research Projects Agency (DARPA) Deep Learning program (FA8650-10-C-7020).","citation":{"short":"S. Lin, C. Uhler, B. Sturmfels, P. Bühlmann, Foundations of Computational Mathematics 14 (2014) 1079–1116.","apa":"Lin, S., Uhler, C., Sturmfels, B., &#38; Bühlmann, P. (2014). Hypersurfaces and their singularities in partial correlation testing. <i>Foundations of Computational Mathematics</i>. Springer. <a href=\"https://doi.org/10.1007/s10208-014-9205-0\">https://doi.org/10.1007/s10208-014-9205-0</a>","ieee":"S. Lin, C. Uhler, B. Sturmfels, and P. Bühlmann, “Hypersurfaces and their singularities in partial correlation testing,” <i>Foundations of Computational Mathematics</i>, vol. 14, no. 5. Springer, pp. 1079–1116, 2014.","ista":"Lin S, Uhler C, Sturmfels B, Bühlmann P. 2014. Hypersurfaces and their singularities in partial correlation testing. Foundations of Computational Mathematics. 14(5), 1079–1116.","ama":"Lin S, Uhler C, Sturmfels B, Bühlmann P. Hypersurfaces and their singularities in partial correlation testing. <i>Foundations of Computational Mathematics</i>. 2014;14(5):1079-1116. doi:<a href=\"https://doi.org/10.1007/s10208-014-9205-0\">10.1007/s10208-014-9205-0</a>","chicago":"Lin, Shaowei, Caroline Uhler, Bernd Sturmfels, and Peter Bühlmann. “Hypersurfaces and Their Singularities in Partial Correlation Testing.” <i>Foundations of Computational Mathematics</i>. Springer, 2014. <a href=\"https://doi.org/10.1007/s10208-014-9205-0\">https://doi.org/10.1007/s10208-014-9205-0</a>.","mla":"Lin, Shaowei, et al. “Hypersurfaces and Their Singularities in Partial Correlation Testing.” <i>Foundations of Computational Mathematics</i>, vol. 14, no. 5, Springer, 2014, pp. 1079–116, doi:<a href=\"https://doi.org/10.1007/s10208-014-9205-0\">10.1007/s10208-014-9205-0</a>."},"isi":1,"corr_author":"1","day":"10","scopus_import":"1","date_created":"2018-12-11T11:55:12Z","arxiv":1,"type":"journal_article","quality_controlled":"1","title":"Hypersurfaces and their singularities in partial correlation testing","oa_version":"Submitted Version","date_published":"2014-10-10T00:00:00Z","publication":"Foundations of Computational Mathematics","publication_status":"published","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","status":"public"},{"author":[{"first_name":"Hiroshi","last_name":"Matsukawa","full_name":"Matsukawa, Hiroshi"},{"full_name":"Akiyoshi Nishimura, Sachiko","last_name":"Akiyoshi Nishimura","first_name":"Sachiko"},{"full_name":"Zhang, Qi","last_name":"Zhang","first_name":"Qi"},{"full_name":"Luján, Rafael","first_name":"Rafael","last_name":"Luján"},{"full_name":"Yamaguchi, Kazuhiko","first_name":"Kazuhiko","last_name":"Yamaguchi"},{"full_name":"Goto, Hiromichi","last_name":"Goto","first_name":"Hiromichi"},{"full_name":"Yaguchi, Kunio","last_name":"Yaguchi","first_name":"Kunio"},{"full_name":"Hashikawa, Tsutomu","first_name":"Tsutomu","last_name":"Hashikawa"},{"full_name":"Sano, Chie","first_name":"Chie","last_name":"Sano"},{"id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","first_name":"Ryuichi","orcid":"0000-0001-8761-9444","last_name":"Shigemoto","full_name":"Shigemoto, Ryuichi"},{"last_name":"Nakashiba","first_name":"Toshiaki","full_name":"Nakashiba, Toshiaki"},{"full_name":"Itohara, Shigeyoshi","last_name":"Itohara","first_name":"Shigeyoshi"}],"page":"15779 - 15792","article_processing_charge":"No","abstract":[{"text":"Synaptic cell adhesion molecules are increasingly gaining attention for conferring specific properties to individual synapses. Netrin-G1 and netrin-G2 are trans-synaptic adhesion molecules that distribute on distinct axons, and their presence restricts the expression of their cognate receptors, NGL1 and NGL2, respectively, to specific subdendritic segments of target neurons. However, the neural circuits and functional roles of netrin-G isoform complexes remain unclear. Here, we use netrin-G-KO and NGL-KO mice to reveal that netrin-G1/NGL1 and netrin-G2/NGL2 interactions specify excitatory synapses in independent hippocampal pathways. In the hippocampal CA1 area, netrin-G1/NGL1 and netrin-G2/NGL2 were expressed in the temporoammonic and Schaffer collateral pathways, respectively. The lack of presynaptic netrin-Gs led to the dispersion of NGLs from postsynaptic membranes. In accord, netrin-G mutant synapses displayed opposing phenotypes in long-term and short-term plasticity through discrete biochemical pathways. The plasticity phenotypes in netrin-G-KOs were phenocopied in NGL-KOs, with a corresponding loss of netrin-Gs from presynaptic membranes. Our findings show that netrin-G/NGL interactions differentially control synaptic plasticity in distinct circuits via retrograde signaling mechanisms and explain how synaptic inputs are diversified to control neuronal activity.","lang":"eng"}],"department":[{"_id":"RySh"}],"doi":"10.1523/JNEUROSCI.1141-14.2014","publist_id":"5054","ddc":["570"],"has_accepted_license":"1","intvolume":"        34","oa":1,"language":[{"iso":"eng"}],"external_id":{"isi":["000345907500026"],"pmid":["25411505"]},"_id":"2018","issue":"47","date_updated":"2025-09-29T12:00:37Z","file_date_updated":"2022-05-24T08:41:41Z","file":[{"access_level":"open_access","date_updated":"2022-05-24T08:41:41Z","checksum":"6913e9bc26e9fc1c0441a739a4199229","file_size":3963728,"date_created":"2022-05-24T08:41:41Z","content_type":"application/pdf","creator":"dernst","file_id":"11410","success":1,"file_name":"2014_JournNeuroscience_Matsukawa.pdf","relation":"main_file"}],"fulldoi":"https://doi.org/10.1523/JNEUROSCI.1141-14.2014","pmid":1,"month":"11","publisher":"Society for Neuroscience","year":"2014","volume":34,"quality_controlled":"1","date_published":"2014-11-19T00:00:00Z","oa_version":"Published Version","title":"Netrin-G/NGL complexes encode functional synaptic diversification","publication_status":"published","publication":"Journal of Neuroscience","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","status":"public","publication_identifier":{"issn":["0270-6474"],"eissn":["1529-2401"]},"acknowledgement":"This work was supported by “Funding Program for World-Leading Innovative R&D on Science and Technology (FIRST Program)” initiated by the Council for Science and Technology Policy.","citation":{"mla":"Matsukawa, Hiroshi, et al. “Netrin-G/NGL Complexes Encode Functional Synaptic Diversification.” <i>Journal of Neuroscience</i>, vol. 34, no. 47, Society for Neuroscience, 2014, pp. 15779–92, doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.1141-14.2014\">10.1523/JNEUROSCI.1141-14.2014</a>.","chicago":"Matsukawa, Hiroshi, Sachiko Akiyoshi Nishimura, Qi Zhang, Rafael Luján, Kazuhiko Yamaguchi, Hiromichi Goto, Kunio Yaguchi, et al. “Netrin-G/NGL Complexes Encode Functional Synaptic Diversification.” <i>Journal of Neuroscience</i>. Society for Neuroscience, 2014. <a href=\"https://doi.org/10.1523/JNEUROSCI.1141-14.2014\">https://doi.org/10.1523/JNEUROSCI.1141-14.2014</a>.","ama":"Matsukawa H, Akiyoshi Nishimura S, Zhang Q, et al. Netrin-G/NGL complexes encode functional synaptic diversification. <i>Journal of Neuroscience</i>. 2014;34(47):15779-15792. doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.1141-14.2014\">10.1523/JNEUROSCI.1141-14.2014</a>","ista":"Matsukawa H, Akiyoshi Nishimura S, Zhang Q, Luján R, Yamaguchi K, Goto H, Yaguchi K, Hashikawa T, Sano C, Shigemoto R, Nakashiba T, Itohara S. 2014. Netrin-G/NGL complexes encode functional synaptic diversification. Journal of Neuroscience. 34(47), 15779–15792.","ieee":"H. Matsukawa <i>et al.</i>, “Netrin-G/NGL complexes encode functional synaptic diversification,” <i>Journal of Neuroscience</i>, vol. 34, no. 47. Society for Neuroscience, pp. 15779–15792, 2014.","apa":"Matsukawa, H., Akiyoshi Nishimura, S., Zhang, Q., Luján, R., Yamaguchi, K., Goto, H., … Itohara, S. (2014). Netrin-G/NGL complexes encode functional synaptic diversification. <i>Journal of Neuroscience</i>. Society for Neuroscience. <a href=\"https://doi.org/10.1523/JNEUROSCI.1141-14.2014\">https://doi.org/10.1523/JNEUROSCI.1141-14.2014</a>","short":"H. Matsukawa, S. Akiyoshi Nishimura, Q. Zhang, R. Luján, K. Yamaguchi, H. Goto, K. Yaguchi, T. Hashikawa, C. Sano, R. Shigemoto, T. Nakashiba, S. Itohara, Journal of Neuroscience 34 (2014) 15779–15792."},"date_created":"2018-12-11T11:55:14Z","day":"19","scopus_import":"1","article_type":"original","isi":1,"type":"journal_article"},{"status":"public","publication_status":"published","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication":"Mathematical Physics, Analysis and Geometry","oa_version":"Submitted Version","title":"Phase transition in the density of states of quantum spin glasses","ec_funded":1,"date_published":"2014-12-17T00:00:00Z","quality_controlled":"1","type":"journal_article","isi":1,"arxiv":1,"day":"17","date_created":"2018-12-11T11:55:15Z","scopus_import":"1","project":[{"call_identifier":"FP7","_id":"258DCDE6-B435-11E9-9278-68D0E5697425","grant_number":"338804","name":"Random matrices, universality and disordered quantum systems"}],"citation":{"mla":"Erdös, László, and Dominik J. Schröder. “Phase Transition in the Density of States of Quantum Spin Glasses.” <i>Mathematical Physics, Analysis and Geometry</i>, vol. 17, no. 3–4, Springer, 2014, pp. 441–64, doi:<a href=\"https://doi.org/10.1007/s11040-014-9164-3\">10.1007/s11040-014-9164-3</a>.","chicago":"Erdös, László, and Dominik J Schröder. “Phase Transition in the Density of States of Quantum Spin Glasses.” <i>Mathematical Physics, Analysis and Geometry</i>. Springer, 2014. <a href=\"https://doi.org/10.1007/s11040-014-9164-3\">https://doi.org/10.1007/s11040-014-9164-3</a>.","ama":"Erdös L, Schröder DJ. Phase transition in the density of states of quantum spin glasses. <i>Mathematical Physics, Analysis and Geometry</i>. 2014;17(3-4):441-464. doi:<a href=\"https://doi.org/10.1007/s11040-014-9164-3\">10.1007/s11040-014-9164-3</a>","ista":"Erdös L, Schröder DJ. 2014. Phase transition in the density of states of quantum spin glasses. Mathematical Physics, Analysis and Geometry. 17(3–4), 441–464.","ieee":"L. Erdös and D. J. Schröder, “Phase transition in the density of states of quantum spin glasses,” <i>Mathematical Physics, Analysis and Geometry</i>, vol. 17, no. 3–4. Springer, pp. 441–464, 2014.","apa":"Erdös, L., &#38; Schröder, D. J. (2014). Phase transition in the density of states of quantum spin glasses. <i>Mathematical Physics, Analysis and Geometry</i>. Springer. <a href=\"https://doi.org/10.1007/s11040-014-9164-3\">https://doi.org/10.1007/s11040-014-9164-3</a>","short":"L. Erdös, D.J. Schröder, Mathematical Physics, Analysis and Geometry 17 (2014) 441–464."},"_id":"2019","issue":"3-4","external_id":{"isi":["000348286700011"],"arxiv":["1407.1552"]},"language":[{"iso":"eng"}],"intvolume":"        17","oa":1,"publist_id":"5053","doi":"10.1007/s11040-014-9164-3","department":[{"_id":"LaEr"}],"abstract":[{"lang":"eng","text":"We prove that the empirical density of states of quantum spin glasses on arbitrary graphs converges to a normal distribution as long as the maximal degree is negligible compared with the total number of edges. This extends the recent results of Keating et al. (2014) that were proved for graphs with bounded chromatic number and with symmetric coupling distribution. Furthermore, we generalise the result to arbitrary hypergraphs. We test the optimality of our condition on the maximal degree for p-uniform hypergraphs that correspond to p-spin glass Hamiltonians acting on n distinguishable spin- 1/2 particles. At the critical threshold p = n1/2 we find a sharp classical-quantum phase transition between the normal distribution and the Wigner semicircle law. The former is characteristic to classical systems with commuting variables, while the latter is a signature of noncommutative random matrix theory."}],"article_processing_charge":"No","page":"441 - 464","author":[{"full_name":"Erdös, László","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","first_name":"László","orcid":"0000-0001-5366-9603","last_name":"Erdös"},{"full_name":"Schröder, Dominik J","first_name":"Dominik J","last_name":"Schröder"}],"main_file_link":[{"url":"http://arxiv.org/abs/1407.1552","open_access":"1"}],"volume":17,"publisher":"Springer","year":"2014","month":"12","fulldoi":"https://doi.org/10.1007/s11040-014-9164-3","date_updated":"2025-09-29T12:00:05Z"},{"citation":{"ama":"Ali S, Hippenmeyer S, Saadat L, Luo L, Weissman I, Ardehali R. Existing cardiomyocytes generate cardiomyocytes at a low rate after birth in mice. <i>PNAS</i>. 2014;111(24):8850-8855. doi:<a href=\"https://doi.org/10.1073/pnas.1408233111\">10.1073/pnas.1408233111</a>","chicago":"Ali, Shah, Simon Hippenmeyer, Lily Saadat, Liqun Luo, Irving Weissman, and Reza Ardehali. “Existing Cardiomyocytes Generate Cardiomyocytes at a Low Rate after Birth in Mice.” <i>PNAS</i>. National Academy of Sciences, 2014. <a href=\"https://doi.org/10.1073/pnas.1408233111\">https://doi.org/10.1073/pnas.1408233111</a>.","mla":"Ali, Shah, et al. “Existing Cardiomyocytes Generate Cardiomyocytes at a Low Rate after Birth in Mice.” <i>PNAS</i>, vol. 111, no. 24, National Academy of Sciences, 2014, pp. 8850–55, doi:<a href=\"https://doi.org/10.1073/pnas.1408233111\">10.1073/pnas.1408233111</a>.","short":"S. Ali, S. Hippenmeyer, L. Saadat, L. Luo, I. Weissman, R. Ardehali, PNAS 111 (2014) 8850–8855.","apa":"Ali, S., Hippenmeyer, S., Saadat, L., Luo, L., Weissman, I., &#38; Ardehali, R. (2014). Existing cardiomyocytes generate cardiomyocytes at a low rate after birth in mice. <i>PNAS</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.1408233111\">https://doi.org/10.1073/pnas.1408233111</a>","ieee":"S. Ali, S. Hippenmeyer, L. Saadat, L. Luo, I. Weissman, and R. Ardehali, “Existing cardiomyocytes generate cardiomyocytes at a low rate after birth in mice,” <i>PNAS</i>, vol. 111, no. 24. National Academy of Sciences, pp. 8850–8855, 2014.","ista":"Ali S, Hippenmeyer S, Saadat L, Luo L, Weissman I, Ardehali R. 2014. Existing cardiomyocytes generate cardiomyocytes at a low rate after birth in mice. PNAS. 111(24), 8850–8855."},"date_created":"2018-12-11T11:55:15Z","day":"17","scopus_import":"1","isi":1,"type":"journal_article","quality_controlled":"1","date_published":"2014-06-17T00:00:00Z","title":"Existing cardiomyocytes generate cardiomyocytes at a low rate after birth in mice","oa_version":"None","publication_status":"published","publication":"PNAS","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","status":"public","date_updated":"2025-09-29T11:59:35Z","fulldoi":"https://doi.org/10.1073/pnas.1408233111","publisher":"National Academy of Sciences","month":"06","year":"2014","volume":111,"author":[{"full_name":"Ali, Shah","last_name":"Ali","first_name":"Shah"},{"full_name":"Hippenmeyer, Simon","first_name":"Simon","id":"37B36620-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2279-1061","last_name":"Hippenmeyer"},{"first_name":"Lily","last_name":"Saadat","full_name":"Saadat, Lily"},{"first_name":"Liqun","last_name":"Luo","full_name":"Luo, Liqun"},{"full_name":"Weissman, Irving","first_name":"Irving","last_name":"Weissman"},{"full_name":"Ardehali, Reza","last_name":"Ardehali","first_name":"Reza"}],"page":"8850 - 8855","article_processing_charge":"No","abstract":[{"text":"The mammalian heart has long been considered a postmitotic organ, implying that the total number of cardiomyocytes is set at birth. Analysis of cell division in the mammalian heart is complicated by cardiomyocyte binucleation shortly after birth, which makes it challenging to interpret traditional assays of cell turnover [Laflamme MA, Murray CE (2011) Nature 473(7347):326–335; Bergmann O, et al. (2009) Science 324(5923):98–102]. An elegant multi-isotope imaging-mass spectrometry technique recently calculated the low, discrete rate of cardiomyocyte generation in mice [Senyo SE, et al. (2013) Nature 493(7432):433–436], yet our cellular-level understanding of postnatal cardiomyogenesis remains limited. Herein, we provide a new line of evidence for the differentiated α-myosin heavy chain-expressing cardiomyocyte as the cell of origin of postnatal cardiomyogenesis using the “mosaic analysis with double markers” mouse model. We show limited, life-long, symmetric division of cardiomyocytes as a rare event that is evident in utero but significantly diminishes after the first month of life in mice; daughter cardiomyocytes divide very seldom, which this study is the first to demonstrate, to our knowledge. Furthermore, ligation of the left anterior descending coronary artery, which causes a myocardial infarction in the mosaic analysis with double-marker mice, did not increase the rate of cardiomyocyte division above the basal level for up to 4 wk after the injury. The clonal analysis described here provides direct evidence of postnatal mammalian cardiomyogenesis.","lang":"eng"}],"department":[{"_id":"SiHi"}],"doi":"10.1073/pnas.1408233111","publist_id":"5052","intvolume":"       111","language":[{"iso":"eng"}],"external_id":{"isi":["000337300100041"]},"issue":"24","_id":"2020"},{"main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631524/","open_access":"1"}],"volume":346,"publisher":"American Association for the Advancement of Science","year":"2014","month":"10","fulldoi":"https://doi.org/10.1126/science.1258996","date_updated":"2025-09-29T11:59:07Z","issue":"6209","_id":"2021","external_id":{"isi":["000343799700047"]},"language":[{"iso":"eng"}],"intvolume":"       346","oa":1,"publist_id":"5051","doi":"10.1126/science.1258996","abstract":[{"lang":"eng","text":"Neurotrophins regulate diverse aspects of neuronal development and plasticity, but their precise in vivo functions during neural circuit assembly in the central brain remain unclear. We show that the neurotrophin receptor tropomyosin-related kinase C (TrkC) is required for dendritic growth and branching of mouse cerebellar Purkinje cells. Sparse TrkC knockout reduced dendrite complexity, but global Purkinje cell knockout had no effect. Removal of the TrkC ligand neurotrophin-3 (NT-3) from cerebellar granule cells, which provide major afferent input to developing Purkinje cell dendrites, rescued the dendrite defects caused by sparse TrkC disruption in Purkinje cells. Our data demonstrate that NT-3 from presynaptic neurons (granule cells) is required for TrkC-dependent competitive dendrite morphogenesis in postsynaptic neurons (Purkinje cells)—a previously unknown mechanism of neural circuit development."}],"department":[{"_id":"SiHi"}],"article_processing_charge":"No","page":"626 - 629","author":[{"first_name":"Joo","last_name":"William","full_name":"William, Joo"},{"full_name":"Hippenmeyer, Simon","first_name":"Simon","orcid":"0000-0003-2279-1061","id":"37B36620-F248-11E8-B48F-1D18A9856A87","last_name":"Hippenmeyer"},{"first_name":"Liqun","last_name":"Luo","full_name":"Luo, Liqun"}],"type":"journal_article","isi":1,"scopus_import":"1","day":"31","date_created":"2018-12-11T11:55:15Z","citation":{"ama":"William J, Hippenmeyer S, Luo L. Dendrite morphogenesis depends on relative levels of NT-3/TrkC signaling. <i>Science</i>. 2014;346(6209):626-629. doi:<a href=\"https://doi.org/10.1126/science.1258996\">10.1126/science.1258996</a>","mla":"William, Joo, et al. “Dendrite Morphogenesis Depends on Relative Levels of NT-3/TrkC Signaling.” <i>Science</i>, vol. 346, no. 6209, American Association for the Advancement of Science, 2014, pp. 626–29, doi:<a href=\"https://doi.org/10.1126/science.1258996\">10.1126/science.1258996</a>.","chicago":"William, Joo, Simon Hippenmeyer, and Liqun Luo. “Dendrite Morphogenesis Depends on Relative Levels of NT-3/TrkC Signaling.” <i>Science</i>. American Association for the Advancement of Science, 2014. <a href=\"https://doi.org/10.1126/science.1258996\">https://doi.org/10.1126/science.1258996</a>.","apa":"William, J., Hippenmeyer, S., &#38; Luo, L. (2014). Dendrite morphogenesis depends on relative levels of NT-3/TrkC signaling. <i>Science</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/science.1258996\">https://doi.org/10.1126/science.1258996</a>","short":"J. William, S. Hippenmeyer, L. Luo, Science 346 (2014) 626–629.","ista":"William J, Hippenmeyer S, Luo L. 2014. Dendrite morphogenesis depends on relative levels of NT-3/TrkC signaling. Science. 346(6209), 626–629.","ieee":"J. William, S. Hippenmeyer, and L. Luo, “Dendrite morphogenesis depends on relative levels of NT-3/TrkC signaling,” <i>Science</i>, vol. 346, no. 6209. American Association for the Advancement of Science, pp. 626–629, 2014."},"status":"public","publication_status":"published","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication":"Science","title":"Dendrite morphogenesis depends on relative levels of NT-3/TrkC signaling","oa_version":"Submitted Version","date_published":"2014-10-31T00:00:00Z","quality_controlled":"1"},{"type":"journal_article","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"isi":1,"corr_author":"1","day":"06","scopus_import":"1","date_created":"2018-12-11T11:55:16Z","project":[{"_id":"25D61E48-B435-11E9-9278-68D0E5697425","grant_number":"618444","name":"Molecular Mechanisms of Cerebral Cortex Development","call_identifier":"FP7"},{"grant_number":"RGP0053/2014","_id":"25D7962E-B435-11E9-9278-68D0E5697425","name":"Quantitative Structure-Function Analysis of Cerebral Cortex Assembly at Clonal Level"}],"citation":{"ama":"Gao P, Postiglione MP, Krieger T, et al. Deterministic progenitor behavior and unitary production of neurons in the neocortex. <i>Cell</i>. 2014;159(4):775-788. doi:<a href=\"https://doi.org/10.1016/j.cell.2014.10.027\">10.1016/j.cell.2014.10.027</a>","chicago":"Gao, Peng, Maria P Postiglione, Teresa Krieger, Luisirene Hernandez, Chao Wang, Zhi Han, Carmen Streicher, et al. “Deterministic Progenitor Behavior and Unitary Production of Neurons in the Neocortex.” <i>Cell</i>. Cell Press, 2014. <a href=\"https://doi.org/10.1016/j.cell.2014.10.027\">https://doi.org/10.1016/j.cell.2014.10.027</a>.","mla":"Gao, Peng, et al. “Deterministic Progenitor Behavior and Unitary Production of Neurons in the Neocortex.” <i>Cell</i>, vol. 159, no. 4, Cell Press, 2014, pp. 775–88, doi:<a href=\"https://doi.org/10.1016/j.cell.2014.10.027\">10.1016/j.cell.2014.10.027</a>.","short":"P. Gao, M.P. Postiglione, T. Krieger, L. Hernandez, C. Wang, Z. Han, C. Streicher, E. Papusheva, R. Insolera, K. Chugh, O. Kodish, K. Huang, B. Simons, L. Luo, S. Hippenmeyer, S. Shi, Cell 159 (2014) 775–788.","apa":"Gao, P., Postiglione, M. P., Krieger, T., Hernandez, L., Wang, C., Han, Z., … Shi, S. (2014). Deterministic progenitor behavior and unitary production of neurons in the neocortex. <i>Cell</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.cell.2014.10.027\">https://doi.org/10.1016/j.cell.2014.10.027</a>","ieee":"P. Gao <i>et al.</i>, “Deterministic progenitor behavior and unitary production of neurons in the neocortex,” <i>Cell</i>, vol. 159, no. 4. Cell Press, pp. 775–788, 2014.","ista":"Gao P, Postiglione MP, Krieger T, Hernandez L, Wang C, Han Z, Streicher C, Papusheva E, Insolera R, Chugh K, Kodish O, Huang K, Simons B, Luo L, Hippenmeyer S, Shi S. 2014. Deterministic progenitor behavior and unitary production of neurons in the neocortex. Cell. 159(4), 775–788."},"license":"https://creativecommons.org/licenses/by/4.0/","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication":"Cell","publication_status":"published","status":"public","ec_funded":1,"title":"Deterministic progenitor behavior and unitary production of neurons in the neocortex","oa_version":"Published Version","date_published":"2014-11-06T00:00:00Z","quality_controlled":"1","publisher":"Cell Press","year":"2014","month":"11","volume":159,"fulldoi":"https://doi.org/10.1016/j.cell.2014.10.027","file":[{"date_created":"2018-12-12T10:08:47Z","content_type":"application/pdf","file_id":"4709","creator":"system","relation":"main_file","file_name":"IST-2016-423-v1+1_1-s2.0-S0092867414013154-main.pdf","access_level":"open_access","date_updated":"2020-07-14T12:45:25Z","checksum":"6c5de8329bb2ffa71cba9fda750f14ce","file_size":4435787}],"file_date_updated":"2020-07-14T12:45:25Z","date_updated":"2025-09-29T11:57:49Z","_id":"2022","issue":"4","language":[{"iso":"eng"}],"external_id":{"isi":["000344522000011"]},"publist_id":"5050","ddc":["570"],"has_accepted_license":"1","oa":1,"intvolume":"       159","pubrep_id":"423","doi":"10.1016/j.cell.2014.10.027","article_processing_charge":"No","abstract":[{"lang":"eng","text":"Radial glial progenitors (RGPs) are responsible for producing nearly all neocortical neurons. To gain insight into the patterns of RGP division and neuron production, we quantitatively analyzed excitatory neuron genesis in the mouse neocortex using Mosaic Analysis with Double Markers, which provides single-cell resolution of progenitor division patterns and potential in vivo. We found that RGPs progress through a coherent program in which their proliferative potential diminishes in a predictable manner. Upon entry into the neurogenic phase, individual RGPs produce ∼8–9 neurons distributed in both deep and superficial layers, indicating a unitary output in neuronal production. Removal of OTX1, a transcription factor transiently expressed in RGPs, results in both deep- and superficial-layer neuron loss and a reduction in neuronal unit size. Moreover, ∼1/6 of neurogenic RGPs proceed to produce glia. These results suggest that progenitor behavior and histogenesis in the mammalian neocortex conform to a remarkably orderly and deterministic program."}],"department":[{"_id":"SiHi"},{"_id":"Bio"}],"author":[{"full_name":"Gao, Peng","first_name":"Peng","last_name":"Gao"},{"last_name":"Postiglione","first_name":"Maria P","id":"2C67902A-F248-11E8-B48F-1D18A9856A87","full_name":"Postiglione, Maria P"},{"full_name":"Krieger, Teresa","last_name":"Krieger","first_name":"Teresa"},{"full_name":"Hernandez, Luisirene","first_name":"Luisirene","last_name":"Hernandez"},{"last_name":"Wang","first_name":"Chao","full_name":"Wang, Chao"},{"full_name":"Han, Zhi","last_name":"Han","first_name":"Zhi"},{"full_name":"Streicher, Carmen","id":"36BCB99C-F248-11E8-B48F-1D18A9856A87","first_name":"Carmen","last_name":"Streicher"},{"full_name":"Papusheva, Ekaterina","last_name":"Papusheva","first_name":"Ekaterina","id":"41DB591E-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Insolera, Ryan","last_name":"Insolera","first_name":"Ryan"},{"full_name":"Chugh, Kritika","first_name":"Kritika","last_name":"Chugh"},{"full_name":"Kodish, Oren","first_name":"Oren","last_name":"Kodish"},{"last_name":"Huang","first_name":"Kun","full_name":"Huang, Kun"},{"full_name":"Simons, Benjamin","last_name":"Simons","first_name":"Benjamin"},{"last_name":"Luo","first_name":"Liqun","full_name":"Luo, Liqun"},{"full_name":"Hippenmeyer, Simon","orcid":"0000-0003-2279-1061","first_name":"Simon","id":"37B36620-F248-11E8-B48F-1D18A9856A87","last_name":"Hippenmeyer"},{"first_name":"Song","last_name":"Shi","full_name":"Shi, Song"}],"page":"775 - 788"},{"type":"journal_article","scopus_import":"1","day":"25","date_created":"2018-12-11T11:55:16Z","isi":1,"citation":{"ama":"Toshima J, Nishinoaki S, Sato Y, et al. Bifurcation of the endocytic pathway into Rab5-dependent and -independent transport to the vacuole. <i>Nature Communications</i>. 2014;5. doi:<a href=\"https://doi.org/10.1038/ncomms4498\">10.1038/ncomms4498</a>","chicago":"Toshima, Junko, Show Nishinoaki, Yoshifumi Sato, Wataru Yamamoto, Daiki Furukawa, Daria E Siekhaus, Akira Sawaguchi, and Jiro Toshima. “Bifurcation of the Endocytic Pathway into Rab5-Dependent and -Independent Transport to the Vacuole.” <i>Nature Communications</i>. Nature Publishing Group, 2014. <a href=\"https://doi.org/10.1038/ncomms4498\">https://doi.org/10.1038/ncomms4498</a>.","mla":"Toshima, Junko, et al. “Bifurcation of the Endocytic Pathway into Rab5-Dependent and -Independent Transport to the Vacuole.” <i>Nature Communications</i>, vol. 5, 3498, Nature Publishing Group, 2014, doi:<a href=\"https://doi.org/10.1038/ncomms4498\">10.1038/ncomms4498</a>.","short":"J. Toshima, S. Nishinoaki, Y. Sato, W. Yamamoto, D. Furukawa, D.E. Siekhaus, A. Sawaguchi, J. Toshima, Nature Communications 5 (2014).","apa":"Toshima, J., Nishinoaki, S., Sato, Y., Yamamoto, W., Furukawa, D., Siekhaus, D. E., … Toshima, J. (2014). Bifurcation of the endocytic pathway into Rab5-dependent and -independent transport to the vacuole. <i>Nature Communications</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/ncomms4498\">https://doi.org/10.1038/ncomms4498</a>","ieee":"J. Toshima <i>et al.</i>, “Bifurcation of the endocytic pathway into Rab5-dependent and -independent transport to the vacuole,” <i>Nature Communications</i>, vol. 5. Nature Publishing Group, 2014.","ista":"Toshima J, Nishinoaki S, Sato Y, Yamamoto W, Furukawa D, Siekhaus DE, Sawaguchi A, Toshima J. 2014. Bifurcation of the endocytic pathway into Rab5-dependent and -independent transport to the vacuole. Nature Communications. 5, 3498."},"status":"public","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication_status":"published","publication":"Nature Communications","date_published":"2014-03-25T00:00:00Z","article_number":"3498","title":"Bifurcation of the endocytic pathway into Rab5-dependent and -independent transport to the vacuole","oa_version":"Submitted Version","quality_controlled":"1","fulldoi":"https://doi.org/10.1038/ncomms4498","volume":5,"year":"2014","month":"03","publisher":"Nature Publishing Group","file_date_updated":"2020-07-14T12:45:25Z","file":[{"date_updated":"2020-07-14T12:45:25Z","access_level":"open_access","file_size":4803515,"checksum":"614fb6579c86d1f95bdd95eeb9ab01b0","date_created":"2018-12-12T10:11:11Z","relation":"main_file","file_name":"IST-2016-616-v1+1_DaSi_Bifurcation_Postprint.pdf","creator":"system","file_id":"4864","content_type":"application/pdf"}],"date_updated":"2025-09-29T11:56:40Z","_id":"2024","oa":1,"has_accepted_license":"1","intvolume":"         5","ddc":["570"],"publist_id":"5048","external_id":{"isi":["000334302000001"]},"language":[{"iso":"eng"}],"abstract":[{"lang":"eng","text":"The yeast Rab5 homologue, Vps21p, is known to be involved both in the vacuolar protein sorting (VPS) pathway from the trans-Golgi network to the vacuole, and in the endocytic pathway from the plasma membrane to the vacuole. However, the intracellular location at which these two pathways converge remains unclear. In addition, the endocytic pathway is not completely blocked in yeast cells lacking all Rab5 genes, suggesting the existence of an unidentified route that bypasses the Rab5-dependent endocytic pathway. Here we show that convergence of the endocytic and VPS pathways occurs upstream of the requirement for Vps21p in these pathways. We also identify a previously unidentified endocytic pathway mediated by the AP-3 complex. Importantly, the AP-3-mediated pathway appears mostly intact in Rab5-disrupted cells, and thus works as an alternative route to the vacuole/lysosome. We propose that the endocytic traffic branches into two routes to reach the vacuole: a Rab5-dependent VPS pathway and a Rab5-independent AP-3-mediated pathway."}],"department":[{"_id":"DaSi"}],"article_processing_charge":"No","doi":"10.1038/ncomms4498","pubrep_id":"616","author":[{"full_name":"Toshima, Junko","last_name":"Toshima","first_name":"Junko"},{"first_name":"Show","last_name":"Nishinoaki","full_name":"Nishinoaki, Show"},{"full_name":"Sato, Yoshifumi","first_name":"Yoshifumi","last_name":"Sato"},{"last_name":"Yamamoto","first_name":"Wataru","full_name":"Yamamoto, Wataru"},{"last_name":"Furukawa","first_name":"Daiki","full_name":"Furukawa, Daiki"},{"full_name":"Siekhaus, Daria E","first_name":"Daria E","id":"3D224B9E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8323-8353","last_name":"Siekhaus"},{"full_name":"Sawaguchi, Akira","first_name":"Akira","last_name":"Sawaguchi"},{"full_name":"Toshima, Jiro","first_name":"Jiro","last_name":"Toshima"}]},{"quality_controlled":"1","conference":{"name":"ATVA: Automated Technology for Verification and Analysis","start_date":"2014-11-03","end_date":"2014-11-07","location":"Sydney, Australia"},"date_published":"2014-01-01T00:00:00Z","title":"Rabinizer 3: Safraless translation of ltl to small deterministic automata","oa_version":"None","ec_funded":1,"status":"public","publication":"Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)","publication_status":"published","user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","editor":[{"full_name":"Cassez, Franck","last_name":"Cassez","first_name":"Franck"},{"last_name":"Raskin","first_name":"Jean-François","full_name":"Raskin, Jean-François"}],"acknowledgement":"Sponsor: P202/12/G061; GACR; Czech Science Foundation\r\n\r\n","citation":{"ama":"Komárková Z, Kretinsky J. Rabinizer 3: Safraless translation of ltl to small deterministic automata. In: Cassez F, Raskin J-F, eds. <i>Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)</i>. Vol 8837. Springer; 2014:235-241. doi:<a href=\"https://doi.org/10.1007/978-3-319-11936-6_17\">10.1007/978-3-319-11936-6_17</a>","mla":"Komárková, Zuzana, and Jan Kretinsky. “Rabinizer 3: Safraless Translation of Ltl to Small Deterministic Automata.” <i>Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)</i>, edited by Franck Cassez and Jean-François Raskin, vol. 8837, Springer, 2014, pp. 235–41, doi:<a href=\"https://doi.org/10.1007/978-3-319-11936-6_17\">10.1007/978-3-319-11936-6_17</a>.","chicago":"Komárková, Zuzana, and Jan Kretinsky. “Rabinizer 3: Safraless Translation of Ltl to Small Deterministic Automata.” In <i>Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)</i>, edited by Franck Cassez and Jean-François Raskin, 8837:235–41. Springer, 2014. <a href=\"https://doi.org/10.1007/978-3-319-11936-6_17\">https://doi.org/10.1007/978-3-319-11936-6_17</a>.","apa":"Komárková, Z., &#38; Kretinsky, J. (2014). Rabinizer 3: Safraless translation of ltl to small deterministic automata. In F. Cassez &#38; J.-F. Raskin (Eds.), <i>Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)</i> (Vol. 8837, pp. 235–241). Sydney, Australia: Springer. <a href=\"https://doi.org/10.1007/978-3-319-11936-6_17\">https://doi.org/10.1007/978-3-319-11936-6_17</a>","short":"Z. Komárková, J. Kretinsky, in:, F. Cassez, J.-F. Raskin (Eds.), Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), Springer, 2014, pp. 235–241.","ista":"Komárková Z, Kretinsky J. 2014. Rabinizer 3: Safraless translation of ltl to small deterministic automata. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). ATVA: Automated Technology for Verification and Analysis, LNCS, vol. 8837, 235–241.","ieee":"Z. Komárková and J. Kretinsky, “Rabinizer 3: Safraless translation of ltl to small deterministic automata,” in <i>Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)</i>, Sydney, Australia, 2014, vol. 8837, pp. 235–241."},"project":[{"name":"Quantitative Reactive Modeling","grant_number":"267989","_id":"25EE3708-B435-11E9-9278-68D0E5697425","call_identifier":"FP7"},{"name":"Moderne Concurrency Paradigms","grant_number":"S11402-N23","_id":"25F5A88A-B435-11E9-9278-68D0E5697425","call_identifier":"FWF"}],"date_created":"2018-12-11T11:55:17Z","scopus_import":"1","day":"01","type":"conference","page":"235 - 241","author":[{"full_name":"Komárková, Zuzana","last_name":"Komárková","first_name":"Zuzana"},{"last_name":"Kretinsky","orcid":"0000-0002-8122-2881","id":"44CEF464-F248-11E8-B48F-1D18A9856A87","first_name":"Jan","full_name":"Kretinsky, Jan"}],"abstract":[{"lang":"eng","text":"We present a tool for translating LTL formulae into deterministic ω-automata. It is the first tool that covers the whole LTL that does not use Safra’s determinization or any of its variants. This leads to smaller automata. There are several outputs of the tool: firstly, deterministic Rabin automata, which are the standard input for probabilistic model checking, e.g. for the probabilistic model-checker PRISM; secondly, deterministic generalized Rabin automata, which can also be used for probabilistic model checking and are sometimes by orders of magnitude smaller. We also link our tool to PRISM and show that this leads to a significant speed-up of probabilistic LTL model checking, especially with the generalized Rabin automata."}],"department":[{"_id":"ToHe"}],"doi":"10.1007/978-3-319-11936-6_17","intvolume":"      8837","publist_id":"5045","language":[{"iso":"eng"}],"_id":"2026","date_updated":"2024-10-21T06:02:50Z","alternative_title":["LNCS"],"fulldoi":"https://doi.org/10.1007/978-3-319-11936-6_17","volume":8837,"month":"01","publisher":"Springer","year":"2014"},{"doi":"10.1209/0295-5075/108/20003","article_processing_charge":"No","department":[{"_id":"RoSe"}],"abstract":[{"text":"Spin-wave theory is a key ingredient in our comprehension of quantum spin systems, and is used successfully for understanding a wide range of magnetic phenomena, including magnon condensation and stability of patterns in dipolar systems. Nevertheless, several decades of research failed to establish the validity of spin-wave theory rigorously, even for the simplest models of quantum spins. A rigorous justification of the method for the three-dimensional quantum Heisenberg ferromagnet at low temperatures is presented here. We derive sharp bounds on its free energy by combining a bosonic formulation of the model introduced by Holstein and Primakoff with probabilistic estimates and operator inequalities.","lang":"eng"}],"author":[{"first_name":"Michele","last_name":"Correggi","full_name":"Correggi, Michele"},{"full_name":"Giuliani, Alessandro","last_name":"Giuliani","first_name":"Alessandro"},{"full_name":"Seiringer, Robert","orcid":"0000-0002-6781-0521","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","first_name":"Robert","last_name":"Seiringer"}],"issue":"2","_id":"2029","language":[{"iso":"eng"}],"external_id":{"isi":["000344913300003"],"arxiv":["1404.4717"]},"publist_id":"5044","oa":1,"intvolume":"       108","date_updated":"2025-09-29T11:55:55Z","main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/1404.4717"}],"month":"10","year":"2014","publisher":"IOP Publishing","volume":108,"fulldoi":"https://doi.org/10.1209/0295-5075/108/20003","title":"Validity of spin-wave theory for the quantum Heisenberg model","article_number":"20003","oa_version":"Submitted Version","date_published":"2014-10-13T00:00:00Z","quality_controlled":"1","publication_status":"published","publication":"EPL","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","status":"public","citation":{"ista":"Correggi M, Giuliani A, Seiringer R. 2014. Validity of spin-wave theory for the quantum Heisenberg model. EPL. 108(2), 20003.","ieee":"M. Correggi, A. Giuliani, and R. Seiringer, “Validity of spin-wave theory for the quantum Heisenberg model,” <i>EPL</i>, vol. 108, no. 2. IOP Publishing, 2014.","apa":"Correggi, M., Giuliani, A., &#38; Seiringer, R. (2014). Validity of spin-wave theory for the quantum Heisenberg model. <i>EPL</i>. IOP Publishing. <a href=\"https://doi.org/10.1209/0295-5075/108/20003\">https://doi.org/10.1209/0295-5075/108/20003</a>","short":"M. Correggi, A. Giuliani, R. Seiringer, EPL 108 (2014).","mla":"Correggi, Michele, et al. “Validity of Spin-Wave Theory for the Quantum Heisenberg Model.” <i>EPL</i>, vol. 108, no. 2, 20003, IOP Publishing, 2014, doi:<a href=\"https://doi.org/10.1209/0295-5075/108/20003\">10.1209/0295-5075/108/20003</a>.","chicago":"Correggi, Michele, Alessandro Giuliani, and Robert Seiringer. “Validity of Spin-Wave Theory for the Quantum Heisenberg Model.” <i>EPL</i>. IOP Publishing, 2014. <a href=\"https://doi.org/10.1209/0295-5075/108/20003\">https://doi.org/10.1209/0295-5075/108/20003</a>.","ama":"Correggi M, Giuliani A, Seiringer R. Validity of spin-wave theory for the quantum Heisenberg model. <i>EPL</i>. 2014;108(2). doi:<a href=\"https://doi.org/10.1209/0295-5075/108/20003\">10.1209/0295-5075/108/20003</a>"},"acknowledgement":"239694; ERC; European Research Council","type":"journal_article","isi":1,"scopus_import":"1","date_created":"2018-12-11T11:55:18Z","day":"13","arxiv":1},{"publisher":"eLife Sciences Publications","year":"2014","month":"12","volume":3,"fulldoi":"https://doi.org/10.7554/eLife.04057","file":[{"creator":"system","file_id":"5094","content_type":"application/pdf","relation":"main_file","file_name":"IST-2016-421-v1+1_e04057.full.pdf","date_created":"2018-12-12T10:14:41Z","file_size":2239563,"checksum":"c240f915450d4ebe8f95043a2a8c7b1a","date_updated":"2020-07-14T12:45:26Z","access_level":"open_access"}],"file_date_updated":"2020-07-14T12:45:26Z","date_updated":"2025-09-29T11:55:24Z","_id":"2031","language":[{"iso":"eng"}],"external_id":{"isi":["000346170300007"]},"publist_id":"5041","ddc":["570"],"intvolume":"         3","has_accepted_license":"1","oa":1,"pubrep_id":"421","doi":"10.7554/eLife.04057","article_processing_charge":"No","department":[{"_id":"PeJo"}],"abstract":[{"lang":"eng","text":"A puzzling property of synaptic transmission, originally established at the neuromuscular junction, is that the time course of transmitter release is independent of the extracellular Ca2+ concentration ([Ca2+]o), whereas the rate of release is highly [Ca2+]o-dependent. Here, we examine the time course of release at inhibitory basket cell-Purkinje cell synapses and show that it is independent of [Ca2+]o. Modeling of Ca2+-dependent transmitter release suggests that the invariant time course of release critically depends on tight coupling between Ca2+ channels and release sensors. Experiments with exogenous Ca2+ chelators reveal that channel-sensor coupling at basket cell-Purkinje cell synapses is very tight, with a mean distance of 10–20 nm. Thus, tight channel-sensor coupling provides a mechanistic explanation for the apparent [Ca2+]o independence of the time course of release."}],"author":[{"last_name":"Arai","id":"32A73F6C-F248-11E8-B48F-1D18A9856A87","first_name":"Itaru","full_name":"Arai, Itaru"},{"full_name":"Jonas, Peter M","first_name":"Peter M","orcid":"0000-0001-5001-4804","id":"353C1B58-F248-11E8-B48F-1D18A9856A87","last_name":"Jonas"}],"type":"journal_article","isi":1,"corr_author":"1","scopus_import":"1","day":"09","date_created":"2018-12-11T11:55:19Z","project":[{"_id":"25C26B1E-B435-11E9-9278-68D0E5697425","grant_number":"P24909-B24","name":"Mechanisms of transmitter release at GABAergic synapses","call_identifier":"FWF"},{"call_identifier":"FP7","_id":"25C0F108-B435-11E9-9278-68D0E5697425","grant_number":"268548","name":"Nanophysiology of fast-spiking, parvalbumin-expressing GABAergic interneurons"}],"citation":{"apa":"Arai,  itaru, &#38; Jonas, P. M. (2014). Nanodomain coupling explains Ca^2+ independence of transmitter release time course at a fast central synapse. <i>ELife</i>. eLife Sciences Publications. <a href=\"https://doi.org/10.7554/eLife.04057\">https://doi.org/10.7554/eLife.04057</a>","short":"itaru Arai, P.M. Jonas, ELife 3 (2014).","ista":"Arai  itaru, Jonas PM. 2014. Nanodomain coupling explains Ca^2+ independence of transmitter release time course at a fast central synapse. eLife. 3.","ieee":"itaru Arai and P. M. Jonas, “Nanodomain coupling explains Ca^2+ independence of transmitter release time course at a fast central synapse,” <i>eLife</i>, vol. 3. eLife Sciences Publications, 2014.","ama":"Arai  itaru, Jonas PM. Nanodomain coupling explains Ca^2+ independence of transmitter release time course at a fast central synapse. <i>eLife</i>. 2014;3. doi:<a href=\"https://doi.org/10.7554/eLife.04057\">10.7554/eLife.04057</a>","mla":"Arai, itaru, and Peter M. Jonas. “Nanodomain Coupling Explains Ca^2+ Independence of Transmitter Release Time Course at a Fast Central Synapse.” <i>ELife</i>, vol. 3, eLife Sciences Publications, 2014, doi:<a href=\"https://doi.org/10.7554/eLife.04057\">10.7554/eLife.04057</a>.","chicago":"Arai, itaru, and Peter M Jonas. “Nanodomain Coupling Explains Ca^2+ Independence of Transmitter Release Time Course at a Fast Central Synapse.” <i>ELife</i>. eLife Sciences Publications, 2014. <a href=\"https://doi.org/10.7554/eLife.04057\">https://doi.org/10.7554/eLife.04057</a>."},"publication_status":"published","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication":"eLife","status":"public","ec_funded":1,"title":"Nanodomain coupling explains Ca^2+ independence of transmitter release time course at a fast central synapse","oa_version":"Submitted Version","date_published":"2014-12-09T00:00:00Z","quality_controlled":"1"},{"oa":1,"has_accepted_license":"1","intvolume":"         1","publist_id":"5040","ddc":["570"],"external_id":{"pmid":["27308360"]},"language":[{"iso":"eng"}],"_id":"2032","issue":"4","author":[{"full_name":"Inglés Prieto, Álvaro","orcid":"0000-0002-5409-8571","id":"2A9DB292-F248-11E8-B48F-1D18A9856A87","first_name":"Álvaro","last_name":"Inglés Prieto"},{"last_name":"Gschaider-Reichhart","orcid":"0000-0002-7218-7738","first_name":"Eva","id":"3FEE232A-F248-11E8-B48F-1D18A9856A87","full_name":"Gschaider-Reichhart, Eva"},{"full_name":"Schelch, Karin","last_name":"Schelch","first_name":"Karin"},{"last_name":"Janovjak","id":"33BA6C30-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8023-9315","first_name":"Harald L","full_name":"Janovjak, Harald L"},{"last_name":"Grusch","first_name":"Michael","full_name":"Grusch, Michael"}],"department":[{"_id":"HaJa"}],"abstract":[{"lang":"eng","text":"As light-based control of fundamental signaling pathways is becoming a reality, the field of optogenetics is rapidly moving beyond neuroscience. We have recently developed receptor tyrosine kinases that are activated by light and control cell proliferation, epithelial–mesenchymal transition, and angiogenic sprouting—cell behaviors central to cancer progression."}],"article_processing_charge":"Yes","doi":"10.4161/23723548.2014.964045","pmid":1,"fulldoi":"https://doi.org/10.4161/23723548.2014.964045","volume":1,"month":"12","publisher":"Taylor & Francis","year":"2014","date_updated":"2025-05-20T07:37:40Z","file_date_updated":"2020-07-14T12:45:26Z","file":[{"date_created":"2019-05-16T13:39:11Z","relation":"main_file","file_name":"2014_Taylor_Alvaro.pdf","file_id":"6464","creator":"kschuh","content_type":"application/pdf","date_updated":"2020-07-14T12:45:26Z","access_level":"open_access","checksum":"44e17ad40577ab46eb602e88a8b0b8fd","file_size":1765933}],"status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","publication":"Molecular and Cellular Oncology","OA_type":"gold","OA_place":"publisher","publication_identifier":{"eissn":["2372-3556"]},"quality_controlled":"1","date_published":"2014-12-31T00:00:00Z","article_number":"e964045","title":"The optogenetic promise for oncology: Episode I","oa_version":"Published Version","article_type":"original","day":"31","scopus_import":"1","date_created":"2018-12-11T11:55:19Z","tmp":{"name":"Creative Commons Attribution-NonCommercial 3.0 Unported (CC BY-NC 3.0)","image":"/images/cc_by_nc.png","legal_code_url":"https://creativecommons.org/licenses/by-nc/3.0/legalcode","short":"CC BY-NC (3.0)"},"type":"journal_article","DOAJ_listed":"1","license":"https://creativecommons.org/licenses/by-nc/3.0/","citation":{"short":"Á. Inglés Prieto, E. Gschaider-Reichhart, K. Schelch, H.L. Janovjak, M. Grusch, Molecular and Cellular Oncology 1 (2014).","apa":"Inglés Prieto, Á., Gschaider-Reichhart, E., Schelch, K., Janovjak, H. L., &#38; Grusch, M. (2014). The optogenetic promise for oncology: Episode I. <i>Molecular and Cellular Oncology</i>. Taylor &#38; Francis. <a href=\"https://doi.org/10.4161/23723548.2014.964045\">https://doi.org/10.4161/23723548.2014.964045</a>","ieee":"Á. Inglés Prieto, E. Gschaider-Reichhart, K. Schelch, H. L. Janovjak, and M. Grusch, “The optogenetic promise for oncology: Episode I,” <i>Molecular and Cellular Oncology</i>, vol. 1, no. 4. Taylor &#38; Francis, 2014.","ista":"Inglés Prieto Á, Gschaider-Reichhart E, Schelch K, Janovjak HL, Grusch M. 2014. The optogenetic promise for oncology: Episode I. Molecular and Cellular Oncology. 1(4), e964045.","ama":"Inglés Prieto Á, Gschaider-Reichhart E, Schelch K, Janovjak HL, Grusch M. The optogenetic promise for oncology: Episode I. <i>Molecular and Cellular Oncology</i>. 2014;1(4). doi:<a href=\"https://doi.org/10.4161/23723548.2014.964045\">10.4161/23723548.2014.964045</a>","chicago":"Inglés Prieto, Álvaro, Eva Gschaider-Reichhart, Karin Schelch, Harald L Janovjak, and Michael Grusch. “The Optogenetic Promise for Oncology: Episode I.” <i>Molecular and Cellular Oncology</i>. Taylor &#38; Francis, 2014. <a href=\"https://doi.org/10.4161/23723548.2014.964045\">https://doi.org/10.4161/23723548.2014.964045</a>.","mla":"Inglés Prieto, Álvaro, et al. “The Optogenetic Promise for Oncology: Episode I.” <i>Molecular and Cellular Oncology</i>, vol. 1, no. 4, e964045, Taylor &#38; Francis, 2014, doi:<a href=\"https://doi.org/10.4161/23723548.2014.964045\">10.4161/23723548.2014.964045</a>."}},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Advances in Neural Information Processing Systems","publication_status":"published","status":"public","conference":{"location":"Montreal, Canada","end_date":"2014-12-13","name":"NIPS: Neural Information Processing Systems","start_date":"2014-12-08"},"quality_controlled":"1","date_published":"2014-12-08T00:00:00Z","oa_version":"Submitted Version","title":"Mind the nuisance: Gaussian process classification using privileged noise","date_created":"2018-12-11T11:55:20Z","day":"08","scopus_import":"1","type":"conference","citation":{"chicago":"Hernandez Lobato, Daniel, Viktoriia Sharmanska, Kristian Kersting, Christoph Lampert, and Novi Quadrianto. “Mind the Nuisance: Gaussian Process Classification Using Privileged Noise.” In <i>Advances in Neural Information Processing Systems</i>, 1:837–45. Neural Information Processing Systems Foundation, 2014.","mla":"Hernandez Lobato, Daniel, et al. “Mind the Nuisance: Gaussian Process Classification Using Privileged Noise.” <i>Advances in Neural Information Processing Systems</i>, vol. 1, no. January, Neural Information Processing Systems Foundation, 2014, pp. 837–45.","ama":"Hernandez Lobato D, Sharmanska V, Kersting K, Lampert C, Quadrianto N. Mind the nuisance: Gaussian process classification using privileged noise. In: <i>Advances in Neural Information Processing Systems</i>. Vol 1. Neural Information Processing Systems Foundation; 2014:837-845.","ieee":"D. Hernandez Lobato, V. Sharmanska, K. Kersting, C. Lampert, and N. Quadrianto, “Mind the nuisance: Gaussian process classification using privileged noise,” in <i>Advances in Neural Information Processing Systems</i>, Montreal, Canada, 2014, vol. 1, no. January, pp. 837–845.","ista":"Hernandez Lobato D, Sharmanska V, Kersting K, Lampert C, Quadrianto N. 2014. Mind the nuisance: Gaussian process classification using privileged noise. Advances in Neural Information Processing Systems. NIPS: Neural Information Processing Systems vol. 1, 837–845.","short":"D. Hernandez Lobato, V. Sharmanska, K. Kersting, C. Lampert, N. Quadrianto, in:, Advances in Neural Information Processing Systems, Neural Information Processing Systems Foundation, 2014, pp. 837–845.","apa":"Hernandez Lobato, D., Sharmanska, V., Kersting, K., Lampert, C., &#38; Quadrianto, N. (2014). Mind the nuisance: Gaussian process classification using privileged noise. In <i>Advances in Neural Information Processing Systems</i> (Vol. 1, pp. 837–845). Montreal, Canada: Neural Information Processing Systems Foundation."},"publist_id":"5038","intvolume":"         1","oa":1,"language":[{"iso":"eng"}],"_id":"2033","issue":"January","author":[{"full_name":"Hernandez Lobato, Daniel","last_name":"Hernandez Lobato","first_name":"Daniel"},{"last_name":"Sharmanska","id":"2EA6D09E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-0192-9308","first_name":"Viktoriia","full_name":"Sharmanska, Viktoriia"},{"first_name":"Kristian","last_name":"Kersting","full_name":"Kersting, Kristian"},{"full_name":"Lampert, Christoph","last_name":"Lampert","orcid":"0000-0001-8622-7887","id":"40C20FD2-F248-11E8-B48F-1D18A9856A87","first_name":"Christoph"},{"full_name":"Quadrianto, Novi","first_name":"Novi","last_name":"Quadrianto"}],"page":"837-845","article_processing_charge":"No","department":[{"_id":"ChLa"}],"abstract":[{"lang":"eng","text":"The learning with privileged information setting has recently attracted a lot of attention within the machine learning community, as it allows the integration of additional knowledge into the training process of a classifier, even when this comes in the form of a data modality that is not available at test time. Here, we show that privileged information can naturally be treated as noise in the latent function of a Gaussian process classifier (GPC). That is, in contrast to the standard GPC setting, the latent function is not just a nuisance but a feature: it becomes a natural measure of confidence about the training data by modulating the slope of the GPC probit likelihood function. Extensive experiments on public datasets show that the proposed GPC method using privileged noise, called GPC+, improves over a standard GPC without privileged knowledge, and also over the current state-of-the-art SVM-based method, SVM+. Moreover, we show that advanced neural networks and deep learning methods can be compressed as privileged information."}],"publisher":"Neural Information Processing Systems Foundation","year":"2014","month":"12","volume":1,"main_file_link":[{"url":"https://papers.nips.cc/paper/5373-mind-the-nuisance-gaussian-process-classification-using-privileged-noise","open_access":"1"}],"date_updated":"2025-06-03T11:45:29Z"},{"has_accepted_license":"1","oa":1,"intvolume":"        10","publist_id":"5012","ddc":["510"],"external_id":{"isi":["000343011700018"]},"language":[{"iso":"eng"}],"issue":"9","_id":"2039","author":[{"full_name":"Chatterjee, Krishnendu","orcid":"0000-0002-4561-241X","id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","first_name":"Krishnendu","last_name":"Chatterjee"},{"first_name":"Andreas","id":"49704004-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8943-0722","last_name":"Pavlogiannis","full_name":"Pavlogiannis, Andreas"},{"last_name":"Adlam","first_name":"Ben","full_name":"Adlam, Ben"},{"full_name":"Nowak, Martin","last_name":"Nowak","first_name":"Martin"}],"department":[{"_id":"KrCh"}],"abstract":[{"text":"A fundamental question in biology is the following: what is the time scale that is needed for evolutionary innovations? There are many results that characterize single steps in terms of the fixation time of new mutants arising in populations of certain size and structure. But here we ask a different question, which is concerned with the much longer time scale of evolutionary trajectories: how long does it take for a population exploring a fitness landscape to find target sequences that encode new biological functions? Our key variable is the length, (Formula presented.) of the genetic sequence that undergoes adaptation. In computer science there is a crucial distinction between problems that require algorithms which take polynomial or exponential time. The latter are considered to be intractable. Here we develop a theoretical approach that allows us to estimate the time of evolution as function of (Formula presented.) We show that adaptation on many fitness landscapes takes time that is exponential in (Formula presented.) even if there are broad selection gradients and many targets uniformly distributed in sequence space. These negative results lead us to search for specific mechanisms that allow evolution to work on polynomial time scales. We study a regeneration process and show that it enables evolution to work in polynomial time.","lang":"eng"}],"article_processing_charge":"No","doi":"10.1371/journal.pcbi.1003818","pubrep_id":"440","fulldoi":"https://doi.org/10.1371/journal.pcbi.1003818","volume":10,"year":"2014","publisher":"Public Library of Science","month":"09","date_updated":"2025-09-29T11:53:46Z","file_date_updated":"2020-07-14T12:45:26Z","file":[{"access_level":"open_access","date_updated":"2020-07-14T12:45:26Z","file_size":1399093,"checksum":"712d4c5787ddf97809cfc962507f0738","date_created":"2018-12-12T10:11:35Z","file_name":"IST-2016-440-v1+1_journal.pcbi.1003818.pdf","relation":"main_file","content_type":"application/pdf","creator":"system","file_id":"4890"}],"status":"public","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication":"PLoS Computational Biology","publication_status":"published","quality_controlled":"1","date_published":"2014-09-11T00:00:00Z","oa_version":"Published Version","article_number":"7p","title":"The time scale of evolutionary innovation","ec_funded":1,"scopus_import":"1","day":"11","date_created":"2018-12-11T11:55:22Z","corr_author":"1","isi":1,"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"type":"journal_article","related_material":{"record":[{"relation":"research_data","id":"9739","status":"public"}]},"citation":{"mla":"Chatterjee, Krishnendu, et al. “The Time Scale of Evolutionary Innovation.” <i>PLoS Computational Biology</i>, vol. 10, no. 9, 7p, Public Library of Science, 2014, doi:<a href=\"https://doi.org/10.1371/journal.pcbi.1003818\">10.1371/journal.pcbi.1003818</a>.","chicago":"Chatterjee, Krishnendu, Andreas Pavlogiannis, Ben Adlam, and Martin Nowak. “The Time Scale of Evolutionary Innovation.” <i>PLoS Computational Biology</i>. Public Library of Science, 2014. <a href=\"https://doi.org/10.1371/journal.pcbi.1003818\">https://doi.org/10.1371/journal.pcbi.1003818</a>.","ama":"Chatterjee K, Pavlogiannis A, Adlam B, Nowak M. The time scale of evolutionary innovation. <i>PLoS Computational Biology</i>. 2014;10(9). doi:<a href=\"https://doi.org/10.1371/journal.pcbi.1003818\">10.1371/journal.pcbi.1003818</a>","ista":"Chatterjee K, Pavlogiannis A, Adlam B, Nowak M. 2014. The time scale of evolutionary innovation. PLoS Computational Biology. 10(9), 7p.","ieee":"K. Chatterjee, A. Pavlogiannis, B. Adlam, and M. Nowak, “The time scale of evolutionary innovation,” <i>PLoS Computational Biology</i>, vol. 10, no. 9. Public Library of Science, 2014.","apa":"Chatterjee, K., Pavlogiannis, A., Adlam, B., &#38; Nowak, M. (2014). The time scale of evolutionary innovation. <i>PLoS Computational Biology</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pcbi.1003818\">https://doi.org/10.1371/journal.pcbi.1003818</a>","short":"K. Chatterjee, A. Pavlogiannis, B. Adlam, M. Nowak, PLoS Computational Biology 10 (2014)."},"project":[{"call_identifier":"FWF","grant_number":"P 23499-N23","_id":"2584A770-B435-11E9-9278-68D0E5697425","name":"Modern Graph Algorithmic Techniques in Formal Verification"},{"name":"Game Theory","grant_number":"S11407","_id":"25863FF4-B435-11E9-9278-68D0E5697425","call_identifier":"FWF"},{"call_identifier":"FP7","grant_number":"279307","_id":"2581B60A-B435-11E9-9278-68D0E5697425","name":"Quantitative Graph Games: Theory and Applications"},{"name":"Microsoft Research Faculty Fellowship","_id":"2587B514-B435-11E9-9278-68D0E5697425"}]},{"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication":"Science","publication_status":"published","status":"public","date_published":"2014-09-26T00:00:00Z","oa_version":"Submitted Version","title":"Coordination of progenitor specification and growth in mouse and chick spinal cord","article_number":"1254927","quality_controlled":"1","type":"journal_article","day":"26","date_created":"2018-12-11T11:55:22Z","scopus_import":"1","isi":1,"citation":{"short":"A. Kicheva, M.T. Bollenbach, A. Ribeiro, H. Pérez Valle, R. Lovell Badge, V. Episkopou, J. Briscoe, Science 345 (2014).","apa":"Kicheva, A., Bollenbach, M. T., Ribeiro, A., Pérez Valle, H., Lovell Badge, R., Episkopou, V., &#38; Briscoe, J. (2014). Coordination of progenitor specification and growth in mouse and chick spinal cord. <i>Science</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/science.1254927\">https://doi.org/10.1126/science.1254927</a>","ieee":"A. Kicheva <i>et al.</i>, “Coordination of progenitor specification and growth in mouse and chick spinal cord,” <i>Science</i>, vol. 345, no. 6204. American Association for the Advancement of Science, 2014.","ista":"Kicheva A, Bollenbach MT, Ribeiro A, Pérez Valle H, Lovell Badge R, Episkopou V, Briscoe J. 2014. Coordination of progenitor specification and growth in mouse and chick spinal cord. Science. 345(6204), 1254927.","ama":"Kicheva A, Bollenbach MT, Ribeiro A, et al. Coordination of progenitor specification and growth in mouse and chick spinal cord. <i>Science</i>. 2014;345(6204). doi:<a href=\"https://doi.org/10.1126/science.1254927\">10.1126/science.1254927</a>","chicago":"Kicheva, Anna, Mark Tobias Bollenbach, Ana Ribeiro, Helena Pérez Valle, Robin Lovell Badge, Vasso Episkopou, and James Briscoe. “Coordination of Progenitor Specification and Growth in Mouse and Chick Spinal Cord.” <i>Science</i>. American Association for the Advancement of Science, 2014. <a href=\"https://doi.org/10.1126/science.1254927\">https://doi.org/10.1126/science.1254927</a>.","mla":"Kicheva, Anna, et al. “Coordination of Progenitor Specification and Growth in Mouse and Chick Spinal Cord.” <i>Science</i>, vol. 345, no. 6204, 1254927, American Association for the Advancement of Science, 2014, doi:<a href=\"https://doi.org/10.1126/science.1254927\">10.1126/science.1254927</a>."},"_id":"2040","issue":"6204","publist_id":"5011","intvolume":"       345","oa":1,"language":[{"iso":"eng"}],"external_id":{"isi":["000342164500032"]},"article_processing_charge":"No","department":[{"_id":"ToBo"}],"abstract":[{"text":"Development requires tissue growth as well as cell diversification. To address how these processes are coordinated, we analyzed the development of molecularly distinct domains of neural progenitors in the mouse and chick neural tube. We show that during development, these domains undergo changes in size that do not scale with changes in overall tissue size. Our data show that domain proportions are first established by opposing morphogen gradients and subsequently controlled by domain-specific regulation of differentiation rate but not differences in proliferation rate. Regulation of differentiation rate is key to maintaining domain proportions while accommodating both intra- and interspecies variations in size. Thus, the sequential control of progenitor specification and differentiation elaborates pattern without requiring that signaling gradients grow as tissues expand. ","lang":"eng"}],"doi":"10.1126/science.1254927","author":[{"full_name":"Kicheva, Anna","first_name":"Anna","last_name":"Kicheva"},{"full_name":"Bollenbach, Mark Tobias","last_name":"Bollenbach","orcid":"0000-0003-4398-476X","id":"3E6DB97A-F248-11E8-B48F-1D18A9856A87","first_name":"Mark Tobias"},{"full_name":"Ribeiro, Ana","first_name":"Ana","last_name":"Ribeiro"},{"last_name":"Pérez Valle","first_name":"Helena","full_name":"Pérez Valle, Helena"},{"full_name":"Lovell Badge, Robin","first_name":"Robin","last_name":"Lovell Badge"},{"last_name":"Episkopou","first_name":"Vasso","full_name":"Episkopou, Vasso"},{"first_name":"James","last_name":"Briscoe","full_name":"Briscoe, James"}],"main_file_link":[{"url":"http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228193/","open_access":"1"}],"fulldoi":"https://doi.org/10.1126/science.1254927","publisher":"American Association for the Advancement of Science","month":"09","year":"2014","volume":345,"date_updated":"2025-09-29T11:53:14Z"},{"external_id":{"isi":["000341953300001"]},"language":[{"iso":"eng"}],"oa":1,"has_accepted_license":"1","intvolume":"         8","ddc":["570"],"publist_id":"5010","_id":"2041","author":[{"last_name":"Jonas","id":"353C1B58-F248-11E8-B48F-1D18A9856A87","first_name":"Peter M","orcid":"0000-0001-5001-4804","full_name":"Jonas, Peter M"},{"full_name":"Lisman, John","first_name":"John","last_name":"Lisman"}],"doi":"10.3389/fncir.2014.00107","pubrep_id":"424","abstract":[{"lang":"eng","text":"The hippocampus mediates several higher brain functions, such as learning, memory, and spatial coding. The input region of the hippocampus, the dentate gyrus, plays a critical role in these processes. Several lines of evidence suggest that the dentate gyrus acts as a preprocessor of incoming information, preparing it for subsequent processing in CA3. For example, the dentate gyrus converts input from the entorhinal cortex, where cells have multiple spatial fields, into the spatially more specific place cell activity characteristic of the CA3 region. Furthermore, the dentate gyrus is involved in pattern separation, transforming relatively similar input patterns into substantially different output patterns. Finally, the dentate gyrus produces a very sparse coding scheme in which only a very small fraction of neurons are active at any one time."}],"department":[{"_id":"PeJo"}],"article_processing_charge":"No","volume":8,"month":"09","publisher":"Frontiers Research Foundation","year":"2014","fulldoi":"https://doi.org/10.3389/fncir.2014.00107","date_updated":"2025-09-29T11:52:44Z","file":[{"date_created":"2018-12-12T10:17:38Z","relation":"main_file","file_name":"IST-2016-424-v1+1_fncir-08-00107.pdf","creator":"system","file_id":"5294","content_type":"application/pdf","date_updated":"2020-07-14T12:45:26Z","access_level":"open_access","file_size":201110,"checksum":"3ca57b164045523f876407e9f13a9fb8"}],"file_date_updated":"2020-07-14T12:45:26Z","status":"public","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication_status":"published","publication":"Frontiers in Neural Circuits","quality_controlled":"1","article_number":"2p","title":"Structure, function and plasticity of hippocampal dentate gyrus microcircuits","oa_version":"Published Version","date_published":"2014-09-10T00:00:00Z","corr_author":"1","isi":1,"scopus_import":"1","day":"10","date_created":"2018-12-11T11:55:22Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"type":"journal_article","citation":{"ieee":"P. M. Jonas and J. Lisman, “Structure, function and plasticity of hippocampal dentate gyrus microcircuits,” <i>Frontiers in Neural Circuits</i>, vol. 8. Frontiers Research Foundation, 2014.","ista":"Jonas PM, Lisman J. 2014. Structure, function and plasticity of hippocampal dentate gyrus microcircuits. Frontiers in Neural Circuits. 8, 2p.","short":"P.M. Jonas, J. Lisman, Frontiers in Neural Circuits 8 (2014).","apa":"Jonas, P. M., &#38; Lisman, J. (2014). Structure, function and plasticity of hippocampal dentate gyrus microcircuits. <i>Frontiers in Neural Circuits</i>. Frontiers Research Foundation. <a href=\"https://doi.org/10.3389/fncir.2014.00107\">https://doi.org/10.3389/fncir.2014.00107</a>","chicago":"Jonas, Peter M, and John Lisman. “Structure, Function and Plasticity of Hippocampal Dentate Gyrus Microcircuits.” <i>Frontiers in Neural Circuits</i>. Frontiers Research Foundation, 2014. <a href=\"https://doi.org/10.3389/fncir.2014.00107\">https://doi.org/10.3389/fncir.2014.00107</a>.","mla":"Jonas, Peter M., and John Lisman. “Structure, Function and Plasticity of Hippocampal Dentate Gyrus Microcircuits.” <i>Frontiers in Neural Circuits</i>, vol. 8, 2p, Frontiers Research Foundation, 2014, doi:<a href=\"https://doi.org/10.3389/fncir.2014.00107\">10.3389/fncir.2014.00107</a>.","ama":"Jonas PM, Lisman J. Structure, function and plasticity of hippocampal dentate gyrus microcircuits. <i>Frontiers in Neural Circuits</i>. 2014;8. doi:<a href=\"https://doi.org/10.3389/fncir.2014.00107\">10.3389/fncir.2014.00107</a>"}},{"date_published":"2014-08-08T00:00:00Z","article_number":"663","title":"Motif depletion in bacteriophages infecting hosts with CRISPR systems","oa_version":"Published Version","quality_controlled":"1","publication":"BMC Genomics","publication_status":"published","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","status":"public","citation":{"apa":"Kupczok, A., &#38; Bollback, J. P. (2014). Motif depletion in bacteriophages infecting hosts with CRISPR systems. <i>BMC Genomics</i>. BioMed Central. <a href=\"https://doi.org/10.1186/1471-2164-15-663\">https://doi.org/10.1186/1471-2164-15-663</a>","short":"A. Kupczok, J.P. Bollback, BMC Genomics 15 (2014).","ista":"Kupczok A, Bollback JP. 2014. Motif depletion in bacteriophages infecting hosts with CRISPR systems. BMC Genomics. 15(1), 663.","ieee":"A. Kupczok and J. P. Bollback, “Motif depletion in bacteriophages infecting hosts with CRISPR systems,” <i>BMC Genomics</i>, vol. 15, no. 1. BioMed Central, 2014.","ama":"Kupczok A, Bollback JP. Motif depletion in bacteriophages infecting hosts with CRISPR systems. <i>BMC Genomics</i>. 2014;15(1). doi:<a href=\"https://doi.org/10.1186/1471-2164-15-663\">10.1186/1471-2164-15-663</a>","mla":"Kupczok, Anne, and Jonathan P. Bollback. “Motif Depletion in Bacteriophages Infecting Hosts with CRISPR Systems.” <i>BMC Genomics</i>, vol. 15, no. 1, 663, BioMed Central, 2014, doi:<a href=\"https://doi.org/10.1186/1471-2164-15-663\">10.1186/1471-2164-15-663</a>.","chicago":"Kupczok, Anne, and Jonathan P Bollback. “Motif Depletion in Bacteriophages Infecting Hosts with CRISPR Systems.” <i>BMC Genomics</i>. BioMed Central, 2014. <a href=\"https://doi.org/10.1186/1471-2164-15-663\">https://doi.org/10.1186/1471-2164-15-663</a>."},"license":"https://creativecommons.org/publicdomain/zero/1.0/","type":"journal_article","tmp":{"name":"Creative Commons Public Domain Dedication (CC0 1.0)","legal_code_url":"https://creativecommons.org/publicdomain/zero/1.0/legalcode","image":"/images/cc_0.png","short":"CC0 (1.0)"},"scopus_import":"1","date_created":"2018-12-11T11:55:23Z","day":"08","isi":1,"corr_author":"1","article_processing_charge":"No","abstract":[{"lang":"eng","text":"Background: CRISPR is a microbial immune system likely to be involved in host-parasite coevolution. It functions using target sequences encoded by the bacterial genome, which interfere with invading nucleic acids using a homology-dependent system. The system also requires protospacer associated motifs (PAMs), short motifs close to the target sequence that are required for interference in CRISPR types I and II. Here, we investigate whether PAMs are depleted in phage genomes due to selection pressure to escape recognition.Results: To this end, we analyzed two data sets. Phages infecting all bacterial hosts were analyzed first, followed by a detailed analysis of phages infecting the genus Streptococcus, where PAMs are best understood. We use two different measures of motif underrepresentation that control for codon bias and the frequency of submotifs. We compare phages infecting species with a particular CRISPR type to those infecting species without that type. Since only known PAMs were investigated, the analysis is restricted to CRISPR types I-C and I-E and in Streptococcus to types I-C and II. We found evidence for PAM depletion in Streptococcus phages infecting hosts with CRISPR type I-C, in Vibrio phages infecting hosts with CRISPR type I-E and in Streptococcus thermopilus phages infecting hosts with type II-A, known as CRISPR3.Conclusions: The observed motif depletion in phages with hosts having CRISPR can be attributed to selection rather than to mutational bias, as mutational bias should affect the phages of all hosts. This observation implies that the CRISPR system has been efficient in the groups discussed here."}],"department":[{"_id":"JoBo"}],"pubrep_id":"396","doi":"10.1186/1471-2164-15-663","author":[{"full_name":"Kupczok, Anne","last_name":"Kupczok","id":"2BB22BC2-F248-11E8-B48F-1D18A9856A87","first_name":"Anne"},{"id":"2C6FA9CC-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-4624-4612","first_name":"Jonathan P","last_name":"Bollback","full_name":"Bollback, Jonathan P"}],"_id":"2042","issue":"1","publist_id":"5009","ddc":["570"],"oa":1,"has_accepted_license":"1","intvolume":"        15","language":[{"iso":"eng"}],"external_id":{"isi":["000341528300001"]},"file_date_updated":"2020-07-14T12:45:26Z","file":[{"date_created":"2018-12-12T10:11:24Z","content_type":"application/pdf","file_id":"4878","creator":"system","file_name":"IST-2015-396-v1+1_1471-2164-15-663.pdf","relation":"main_file","date_updated":"2020-07-14T12:45:26Z","access_level":"open_access","file_size":1489769,"checksum":"3f6d2776b90a842a28359cc957d3d04b"}],"date_updated":"2025-09-29T11:52:17Z","fulldoi":"https://doi.org/10.1186/1471-2164-15-663","month":"08","publisher":"BioMed Central","year":"2014","volume":15},{"article_processing_charge":"No","department":[{"_id":"HeEd"}],"abstract":[{"lang":"eng","text":"Persistent homology is a popular and powerful tool for capturing topological features of data. Advances in algorithms for computing persistent homology have reduced the computation time drastically – as long as the algorithm does not exhaust the available memory. Following up on a recently presented parallel method for persistence computation on shared memory systems [1], we demonstrate that a simple adaption of the standard reduction algorithm leads to a variant for distributed systems. Our algorithmic design ensures that the data is distributed over the nodes without redundancy; this permits the computation of much larger instances than on a single machine. Moreover, we observe that the parallelism at least compensates for the overhead caused by communication between nodes, and often even speeds up the computation compared to sequential and even parallel shared memory algorithms. In our experiments, we were able to compute the persistent homology of filtrations with more than a billion (109) elements within seconds on a cluster with 32 nodes using less than 6GB of memory per node."}],"doi":"10.1137/1.9781611973198.4","author":[{"full_name":"Bauer, Ulrich","first_name":"Ulrich","orcid":"0000-0002-9683-0724","id":"2ADD483A-F248-11E8-B48F-1D18A9856A87","last_name":"Bauer"},{"orcid":"0000-0002-8030-9299","first_name":"Michael","last_name":"Kerber","full_name":"Kerber, Michael"},{"full_name":"Reininghaus, Jan","id":"4505473A-F248-11E8-B48F-1D18A9856A87","first_name":"Jan","last_name":"Reininghaus"}],"page":"31 - 38","_id":"2043","publist_id":"5008","oa":1,"language":[{"iso":"eng"}],"external_id":{"arxiv":["1310.0710"]},"date_updated":"2025-06-11T08:03:07Z","main_file_link":[{"url":"http://arxiv.org/abs/1310.0710","open_access":"1"}],"fulldoi":"https://doi.org/10.1137/1.9781611973198.4","publisher":"Society for Industrial and Applied Mathematics","month":"01","year":"2014","date_published":"2014-01-01T00:00:00Z","ec_funded":1,"oa_version":"Submitted Version","title":"Distributed computation of persistent homology","conference":{"name":"ALENEX: Algorithm Engineering and Experiments","start_date":"2014-01-05","location":"Portland, USA","end_date":"2014-01-05"},"quality_controlled":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Proceedings of the Workshop on Algorithm Engineering and Experiments","editor":[{"last_name":" McGeoch","first_name":"Catherine","full_name":" McGeoch, Catherine"},{"last_name":"Meyer","first_name":"Ulrich","full_name":"Meyer, Ulrich"}],"publication_status":"published","status":"public","citation":{"ista":"Bauer U, Kerber M, Reininghaus J. 2014. Distributed computation of persistent homology. Proceedings of the Workshop on Algorithm Engineering and Experiments. ALENEX: Algorithm Engineering and Experiments, 31–38.","ieee":"U. Bauer, M. Kerber, and J. Reininghaus, “Distributed computation of persistent homology,” in <i>Proceedings of the Workshop on Algorithm Engineering and Experiments</i>, Portland, USA, 2014, pp. 31–38.","apa":"Bauer, U., Kerber, M., &#38; Reininghaus, J. (2014). Distributed computation of persistent homology. In C.  McGeoch &#38; U. Meyer (Eds.), <i>Proceedings of the Workshop on Algorithm Engineering and Experiments</i> (pp. 31–38). Portland, USA: Society for Industrial and Applied Mathematics. <a href=\"https://doi.org/10.1137/1.9781611973198.4\">https://doi.org/10.1137/1.9781611973198.4</a>","short":"U. Bauer, M. Kerber, J. Reininghaus, in:, C.  McGeoch, U. Meyer (Eds.), Proceedings of the Workshop on Algorithm Engineering and Experiments, Society for Industrial and Applied Mathematics, 2014, pp. 31–38.","mla":"Bauer, Ulrich, et al. “Distributed Computation of Persistent Homology.” <i>Proceedings of the Workshop on Algorithm Engineering and Experiments</i>, edited by Catherine  McGeoch and Ulrich Meyer, Society for Industrial and Applied Mathematics, 2014, pp. 31–38, doi:<a href=\"https://doi.org/10.1137/1.9781611973198.4\">10.1137/1.9781611973198.4</a>.","chicago":"Bauer, Ulrich, Michael Kerber, and Jan Reininghaus. “Distributed Computation of Persistent Homology.” In <i>Proceedings of the Workshop on Algorithm Engineering and Experiments</i>, edited by Catherine  McGeoch and Ulrich Meyer, 31–38. Society for Industrial and Applied Mathematics, 2014. <a href=\"https://doi.org/10.1137/1.9781611973198.4\">https://doi.org/10.1137/1.9781611973198.4</a>.","ama":"Bauer U, Kerber M, Reininghaus J. Distributed computation of persistent homology. In:  McGeoch C, Meyer U, eds. <i>Proceedings of the Workshop on Algorithm Engineering and Experiments</i>. Society for Industrial and Applied Mathematics; 2014:31-38. doi:<a href=\"https://doi.org/10.1137/1.9781611973198.4\">10.1137/1.9781611973198.4</a>"},"project":[{"call_identifier":"FP7","name":"Topological Complex Systems","_id":"255D761E-B435-11E9-9278-68D0E5697425","grant_number":"318493"}],"type":"conference","scopus_import":"1","day":"01","date_created":"2018-12-11T11:55:23Z","arxiv":1},{"type":"book_chapter","corr_author":"1","scopus_import":"1","date_created":"2018-12-11T11:55:23Z","day":"19","arxiv":1,"project":[{"_id":"255D761E-B435-11E9-9278-68D0E5697425","grant_number":"318493","name":"Topological Complex Systems","call_identifier":"FP7"}],"citation":{"short":"U. Bauer, M. Kerber, J. Reininghaus, in:, P.-T. Bremer, I. Hotz, V. Pascucci, R. Peikert (Eds.), Topological Methods in Data Analysis and Visualization III, Springer, 2014, pp. 103–117.","apa":"Bauer, U., Kerber, M., &#38; Reininghaus, J. (2014). Clear and Compress: Computing Persistent Homology in Chunks. In P.-T. Bremer, I. Hotz, V. Pascucci, &#38; R. Peikert (Eds.), <i>Topological Methods in Data Analysis and Visualization III</i> (pp. 103–117). Springer. <a href=\"https://doi.org/10.1007/978-3-319-04099-8_7\">https://doi.org/10.1007/978-3-319-04099-8_7</a>","ieee":"U. Bauer, M. Kerber, and J. Reininghaus, “Clear and Compress: Computing Persistent Homology in Chunks,” in <i>Topological Methods in Data Analysis and Visualization III</i>, P.-T. Bremer, I. Hotz, V. Pascucci, and R. Peikert, Eds. Springer, 2014, pp. 103–117.","ista":"Bauer U, Kerber M, Reininghaus J. 2014.Clear and Compress: Computing Persistent Homology in Chunks. In: Topological Methods in Data Analysis and Visualization III. , 103–117.","ama":"Bauer U, Kerber M, Reininghaus J. Clear and Compress: Computing Persistent Homology in Chunks. In: Bremer P-T, Hotz I, Pascucci V, Peikert R, eds. <i>Topological Methods in Data Analysis and Visualization III</i>. Mathematics and Visualization. Springer; 2014:103-117. doi:<a href=\"https://doi.org/10.1007/978-3-319-04099-8_7\">10.1007/978-3-319-04099-8_7</a>","chicago":"Bauer, Ulrich, Michael Kerber, and Jan Reininghaus. “Clear and Compress: Computing Persistent Homology in Chunks.” In <i>Topological Methods in Data Analysis and Visualization III</i>, edited by Peer-Timo Bremer, Ingrid Hotz, Valerio Pascucci, and Ronald Peikert, 103–17. Mathematics and Visualization. Springer, 2014. <a href=\"https://doi.org/10.1007/978-3-319-04099-8_7\">https://doi.org/10.1007/978-3-319-04099-8_7</a>.","mla":"Bauer, Ulrich, et al. “Clear and Compress: Computing Persistent Homology in Chunks.” <i>Topological Methods in Data Analysis and Visualization III</i>, edited by Peer-Timo Bremer et al., Springer, 2014, pp. 103–17, doi:<a href=\"https://doi.org/10.1007/978-3-319-04099-8_7\">10.1007/978-3-319-04099-8_7</a>."},"publication":"Topological Methods in Data Analysis and Visualization III","editor":[{"full_name":"Bremer, Peer-Timo","first_name":"Peer-Timo","last_name":"Bremer"},{"full_name":"Hotz, Ingrid","first_name":"Ingrid","last_name":"Hotz"},{"last_name":"Pascucci","first_name":"Valerio","full_name":"Pascucci, Valerio"},{"first_name":"Ronald","last_name":"Peikert","full_name":"Peikert, Ronald"}],"publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","ec_funded":1,"title":"Clear and Compress: Computing Persistent Homology in Chunks","oa_version":"Submitted Version","date_published":"2014-03-19T00:00:00Z","quality_controlled":"1","main_file_link":[{"url":"http://arxiv.org/abs/1303.0477","open_access":"1"}],"series_title":"Mathematics and Visualization","year":"2014","month":"03","publisher":"Springer","fulldoi":"https://doi.org/10.1007/978-3-319-04099-8_7","date_updated":"2025-06-11T07:56:57Z","_id":"2044","language":[{"iso":"eng"}],"external_id":{"arxiv":["1303.0477"]},"publist_id":"5007","oa":1,"doi":"10.1007/978-3-319-04099-8_7","article_processing_charge":"No","abstract":[{"lang":"eng","text":"We present a parallel algorithm for computing the persistent homology of a filtered chain complex. Our approach differs from the commonly used reduction algorithm by first computing persistence pairs within local chunks, then simplifying the unpaired columns, and finally applying standard reduction on the simplified matrix. The approach generalizes a technique by Günther et al., which uses discrete Morse Theory to compute persistence; we derive the same worst-case complexity bound in a more general context. The algorithm employs several practical optimization techniques, which are of independent interest. Our sequential implementation of the algorithm is competitive with state-of-the-art methods, and we further improve the performance through parallel computation."}],"department":[{"_id":"HeEd"}],"author":[{"id":"2ADD483A-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-9683-0724","first_name":"Ulrich","last_name":"Bauer","full_name":"Bauer, Ulrich"},{"orcid":"0000-0002-8030-9299","first_name":"Michael","last_name":"Kerber","full_name":"Kerber, Michael"},{"last_name":"Reininghaus","first_name":"Jan","id":"4505473A-F248-11E8-B48F-1D18A9856A87","full_name":"Reininghaus, Jan"}],"page":"103 - 117"},{"_id":"2045","language":[{"iso":"eng"}],"publist_id":"5006","intvolume":"      8383","oa":1,"doi":"10.1007/978-3-642-54631-0_19","department":[{"_id":"KrPi"}],"abstract":[{"lang":"eng","text":"We introduce and study a new notion of enhanced chosen-ciphertext security (ECCA) for public-key encryption. Loosely speaking, in the ECCA security experiment, the decryption oracle provided to the adversary is augmented to return not only the output of the decryption algorithm on a queried ciphertext but also of a randomness-recovery algorithm associated to the scheme. Our results mainly concern the case where the randomness-recovery algorithm is efficient. We provide constructions of ECCA-secure encryption from adaptive trapdoor functions as defined by Kiltz et al. (EUROCRYPT 2010), resulting in ECCA encryption from standard number-theoretic assumptions. We then give two applications of ECCA-secure encryption: (1) We use it as a unifying concept in showing equivalence of adaptive trapdoor functions and tag-based adaptive trapdoor functions, resolving an open question of Kiltz et al. (2) We show that ECCA-secure encryption can be used to securely realize an approach to public-key encryption with non-interactive opening (PKENO) originally suggested by Damgård and Thorbek (EUROCRYPT 2007), resulting in new and practical PKENO schemes quite different from those in prior work. Our results demonstrate that ECCA security is of both practical and theoretical interest."}],"author":[{"full_name":"Dachman Soled, Dana","first_name":"Dana","last_name":"Dachman Soled"},{"id":"46B4C3EE-F248-11E8-B48F-1D18A9856A87","first_name":"Georg","last_name":"Fuchsbauer","full_name":"Fuchsbauer, Georg"},{"full_name":"Mohassel, Payman","last_name":"Mohassel","first_name":"Payman"},{"first_name":"Adam","last_name":"O’Neill","full_name":"O’Neill, Adam"}],"page":"329 - 344","main_file_link":[{"url":"https://eprint.iacr.org/2012/543","open_access":"1"}],"publisher":"Springer","year":"2014","month":"01","volume":8383,"fulldoi":"https://doi.org/10.1007/978-3-642-54631-0_19","alternative_title":["LNCS"],"date_updated":"2021-01-12T06:54:57Z","user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","editor":[{"full_name":"Krawczyk, Hugo","last_name":"Krawczyk","first_name":"Hugo"}],"publication":"Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)","publication_status":"published","status":"public","ec_funded":1,"oa_version":"Submitted Version","title":"Enhanced chosen-ciphertext security and applications","date_published":"2014-01-01T00:00:00Z","conference":{"location":"Buenos Aires, Argentina","end_date":"2014-03-28","start_date":"2014-03-26","name":"PKC: Public Key Crypography"},"quality_controlled":"1","type":"conference","scopus_import":1,"day":"01","date_created":"2018-12-11T11:55:24Z","project":[{"call_identifier":"FP7","_id":"258C570E-B435-11E9-9278-68D0E5697425","grant_number":"259668","name":"Provable Security for Physical Cryptography"}],"citation":{"apa":"Dachman Soled, D., Fuchsbauer, G., Mohassel, P., &#38; O’Neill, A. (2014). Enhanced chosen-ciphertext security and applications. In H. Krawczyk (Ed.), <i>Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)</i> (Vol. 8383, pp. 329–344). Buenos Aires, Argentina: Springer. <a href=\"https://doi.org/10.1007/978-3-642-54631-0_19\">https://doi.org/10.1007/978-3-642-54631-0_19</a>","short":"D. Dachman Soled, G. Fuchsbauer, P. Mohassel, A. O’Neill, in:, H. Krawczyk (Ed.), Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), Springer, 2014, pp. 329–344.","ista":"Dachman Soled D, Fuchsbauer G, Mohassel P, O’Neill A. 2014. Enhanced chosen-ciphertext security and applications. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). PKC: Public Key Crypography, LNCS, vol. 8383, 329–344.","ieee":"D. Dachman Soled, G. Fuchsbauer, P. Mohassel, and A. O’Neill, “Enhanced chosen-ciphertext security and applications,” in <i>Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)</i>, Buenos Aires, Argentina, 2014, vol. 8383, pp. 329–344.","ama":"Dachman Soled D, Fuchsbauer G, Mohassel P, O’Neill A. Enhanced chosen-ciphertext security and applications. In: Krawczyk H, ed. <i>Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)</i>. Vol 8383. Springer; 2014:329-344. doi:<a href=\"https://doi.org/10.1007/978-3-642-54631-0_19\">10.1007/978-3-642-54631-0_19</a>","mla":"Dachman Soled, Dana, et al. “Enhanced Chosen-Ciphertext Security and Applications.” <i>Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)</i>, edited by Hugo Krawczyk, vol. 8383, Springer, 2014, pp. 329–44, doi:<a href=\"https://doi.org/10.1007/978-3-642-54631-0_19\">10.1007/978-3-642-54631-0_19</a>.","chicago":"Dachman Soled, Dana, Georg Fuchsbauer, Payman Mohassel, and Adam O’Neill. “Enhanced Chosen-Ciphertext Security and Applications.” In <i>Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)</i>, edited by Hugo Krawczyk, 8383:329–44. Springer, 2014. <a href=\"https://doi.org/10.1007/978-3-642-54631-0_19\">https://doi.org/10.1007/978-3-642-54631-0_19</a>."},"acknowledgement":"The second author was supported by EPSRC grant EP/H043454/1."},{"language":[{"iso":"eng"}],"oa":1,"intvolume":"      8383","publist_id":"5005","_id":"2046","page":"520 - 537","author":[{"last_name":"Bellare","first_name":"Mihir","full_name":"Bellare, Mihir"},{"full_name":"Fuchsbauer, Georg","last_name":"Fuchsbauer","id":"46B4C3EE-F248-11E8-B48F-1D18A9856A87","first_name":"Georg"}],"doi":"10.1007/978-3-642-54631-0_30","abstract":[{"text":"We introduce policy-based signatures (PBS), where a signer can only sign messages conforming to some authority-specified policy. The main requirements are unforgeability and privacy, the latter meaning that signatures not reveal the policy. PBS offers value along two fronts: (1) On the practical side, they allow a corporation to control what messages its employees can sign under the corporate key. (2) On the theoretical side, they unify existing work, capturing other forms of signatures as special cases or allowing them to be easily built. Our work focuses on definitions of PBS, proofs that this challenging primitive is realizable for arbitrary policies, efficient constructions for specific policies, and a few representative applications.","lang":"eng"}],"department":[{"_id":"KrPi"}],"volume":8383,"year":"2014","month":"01","publisher":"Springer","alternative_title":["LNCS"],"fulldoi":"https://doi.org/10.1007/978-3-642-54631-0_30","main_file_link":[{"url":"https://eprint.iacr.org/2013/413","open_access":"1"}],"date_updated":"2021-01-12T06:54:57Z","status":"public","editor":[{"full_name":"Krawczyk, Hugo","first_name":"Hugo","last_name":"Krawczyk"}],"user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","publication_status":"published","publication":"Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)","quality_controlled":"1","conference":{"name":"PKC: Public Key Crypography","start_date":"2014-05-26","location":"Buenos Aires, Argentina","end_date":"2014-05-28"},"oa_version":"Submitted Version","title":"Policy-based signatures","ec_funded":1,"date_published":"2014-01-01T00:00:00Z","day":"01","scopus_import":1,"date_created":"2018-12-11T11:55:24Z","type":"conference","acknowledgement":"Part of his work was done while at Bristol University, supported by EPSRC grant EP/H043454/1.","project":[{"grant_number":"259668","_id":"258C570E-B435-11E9-9278-68D0E5697425","name":"Provable Security for Physical Cryptography","call_identifier":"FP7"}],"citation":{"ama":"Bellare M, Fuchsbauer G. Policy-based signatures. In: Krawczyk H, ed. <i>Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)</i>. Vol 8383. Springer; 2014:520-537. doi:<a href=\"https://doi.org/10.1007/978-3-642-54631-0_30\">10.1007/978-3-642-54631-0_30</a>","chicago":"Bellare, Mihir, and Georg Fuchsbauer. “Policy-Based Signatures.” In <i>Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)</i>, edited by Hugo Krawczyk, 8383:520–37. Springer, 2014. <a href=\"https://doi.org/10.1007/978-3-642-54631-0_30\">https://doi.org/10.1007/978-3-642-54631-0_30</a>.","mla":"Bellare, Mihir, and Georg Fuchsbauer. “Policy-Based Signatures.” <i>Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)</i>, edited by Hugo Krawczyk, vol. 8383, Springer, 2014, pp. 520–37, doi:<a href=\"https://doi.org/10.1007/978-3-642-54631-0_30\">10.1007/978-3-642-54631-0_30</a>.","short":"M. Bellare, G. Fuchsbauer, in:, H. Krawczyk (Ed.), Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), Springer, 2014, pp. 520–537.","apa":"Bellare, M., &#38; Fuchsbauer, G. (2014). Policy-based signatures. In H. Krawczyk (Ed.), <i>Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)</i> (Vol. 8383, pp. 520–537). Buenos Aires, Argentina: Springer. <a href=\"https://doi.org/10.1007/978-3-642-54631-0_30\">https://doi.org/10.1007/978-3-642-54631-0_30</a>","ieee":"M. Bellare and G. Fuchsbauer, “Policy-based signatures,” in <i>Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)</i>, Buenos Aires, Argentina, 2014, vol. 8383, pp. 520–537.","ista":"Bellare M, Fuchsbauer G. 2014. Policy-based signatures. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). PKC: Public Key Crypography, LNCS, vol. 8383, 520–537."}}]