[{"intvolume":" 694","file_date_updated":"2025-03-04T09:29:01Z","oa_version":"Published Version","publication":"Astronomy & Astrophysics","oa":1,"date_updated":"2026-02-16T12:08:59Z","file":[{"success":1,"date_updated":"2025-03-04T09:29:01Z","file_id":"19285","creator":"dernst","file_name":"2025_AstronomyAstrophysics_CoveloPaz.pdf","file_size":1865856,"checksum":"b1e74644a0cd37550e9a553f8675c93f","relation":"main_file","access_level":"open_access","date_created":"2025-03-04T09:29:01Z","content_type":"application/pdf"}],"isi":1,"related_material":{"link":[{"relation":"software","url":" https://github.com/astroalba/fresco"}]},"article_type":"original","department":[{"_id":"JoMa"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2025-03-02T23:01:54Z","month":"02","_id":"19284","publisher":"EDP Sciences","status":"public","license":"https://creativecommons.org/licenses/by/4.0/","quality_controlled":"1","title":"An Hα view of galaxy buildup in the first 2 Gyr: Luminosity functions at z ∼ 4−6.5 from NIRCam/grism spectroscopy","abstract":[{"text":"The Hα nebular emission line is an optimal tracer for recent star formation in galaxies. With the advent of JWST, this line has recently become observable at z > 3 for the first time. We present a catalog of 1050 Hα emitters at 3.7 < z < 6.7 in the GOODS fields obtained from a blind search in JWST NIRCam/grism data. We made use of the FRESCO survey’s 124 arcmin2 of observations in GOODS-North and GOODS-South with the F444W filter, probing Hα at 4.9 < z < 6.7, and the CONGRESS survey’s 62 arcmin2 of observations in GOODS-North with F356W, probing Hα at 3.8 < z < 5.1. We found an overdensity with 98 sources at z ∼ 4.4 in GOODS-N, and confirmed previously reported overdensities at z ∼ 5.2 in GOODS-N and at z ∼ 5.4 and z ∼ 5.9 in GOODS-S. We computed the observed Hα luminosity functions (LFs) in three bins centered at z ∼ 4.45, 5.30, and 6.15, which are the first such measurements at z > 3 obtained based purely on spectroscopic data, robustly tracing galaxy star formation rates (SFRs) beyond the peak of the cosmic star formation history. We compared our results with theoretical predictions from three different simulations and found good agreement at z ∼ 4 − 6. The UV LFs of this spectroscopically confirmed sample are in good agreement with pre-JWST measurements obtained with photometrically selected objects. Finally, we derived SFR functions and integrated them to compute the evolution of the cosmic SFR densities across z ∼ 4 − 6, finding values in good agreement with recent UV estimates from Lyman-break galaxies, which imply a continuous decrease in SFR density by a factor of three over z ∼ 4 to z ∼ 6. Our work shows the power of NIRCam grism observations to efficiently provide new tests for early galaxy formation models based on emission line statistics.","lang":"eng"}],"acknowledgement":"This work is based on observations made with the NASA/ESA/CSA James Webb Space Telescope. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with program Nos. 1895 and 3577. The authors sincerely thank the CONGRESS team (PIs: Egami & Sun) for developing their observing program with a zero-exclusive-access period. We thank Aswin Vijayan and Harley Katz for their help in analyzing the simulation data from FLARES and SPHINX. This work has received funding from the Swiss State Secretariat for Education, Research, and Innovation (SERI) under contract number MB22.00072, as well as from the Swiss National Science Foundation (SNSF) through project grant 200020_207349. The Cosmic Dawn Center (DAWN) is funded by the Danish National Research Foundation under grant DNRF140. Support for program #1895 was provided by NASA through a grant from the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127. Support for this work for RPN was provided by NASA through the NASA Hubble Fellowship grant HST-HF2-51515.001-A awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Incorporated, under NASA contract NAS5-26555. MS acknowledges support from the European Research Commission Consolidator Grant 101088789 (SFEER), from the CIDEGENT/2021/059 grant by Generalitat Valenciana, and from project PID2023-149420NB-I00 funded by MICIU/AEI/10.13039/501100011033 and by ERDF/EU.","year":"2025","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"volume":694,"publication_status":"published","citation":{"chicago":"Covelo-Paz, Alba, Emma Giovinazzo, Pascal A. Oesch, Romain A. Meyer, Andrea Weibel, Gabriel Brammer, Yoshinobu Fudamoto, et al. “An Hα View of Galaxy Buildup in the First 2 Gyr: Luminosity Functions at z ∼ 4−6.5 from NIRCam/Grism Spectroscopy.” Astronomy & Astrophysics. EDP Sciences, 2025. https://doi.org/10.1051/0004-6361/202452363.","apa":"Covelo-Paz, A., Giovinazzo, E., Oesch, P. A., Meyer, R. A., Weibel, A., Brammer, G., … Xiao, M. (2025). An Hα view of galaxy buildup in the first 2 Gyr: Luminosity functions at z ∼ 4−6.5 from NIRCam/grism spectroscopy. Astronomy & Astrophysics. EDP Sciences. https://doi.org/10.1051/0004-6361/202452363","short":"A. Covelo-Paz, E. Giovinazzo, P.A. Oesch, R.A. Meyer, A. Weibel, G. Brammer, Y. Fudamoto, J. Kerutt, J. Lin, J. Matharu, R.P. Naidu, A. Velichko, V. Bollo, R. Bouwens, J. Chisholm, G.D. Illingworth, I. Kramarenko, D. Magee, M. Maseda, J.J. Matthee, E. Nelson, N. Reddy, D. Schaerer, M. Stefanon, M. Xiao, Astronomy & Astrophysics 694 (2025).","ieee":"A. Covelo-Paz et al., “An Hα view of galaxy buildup in the first 2 Gyr: Luminosity functions at z ∼ 4−6.5 from NIRCam/grism spectroscopy,” Astronomy & Astrophysics, vol. 694. EDP Sciences, 2025.","ista":"Covelo-Paz A, Giovinazzo E, Oesch PA, Meyer RA, Weibel A, Brammer G, Fudamoto Y, Kerutt J, Lin J, Matharu J, Naidu RP, Velichko A, Bollo V, Bouwens R, Chisholm J, Illingworth GD, Kramarenko I, Magee D, Maseda M, Matthee JJ, Nelson E, Reddy N, Schaerer D, Stefanon M, Xiao M. 2025. An Hα view of galaxy buildup in the first 2 Gyr: Luminosity functions at z ∼ 4−6.5 from NIRCam/grism spectroscopy. Astronomy & Astrophysics. 694, A178.","ama":"Covelo-Paz A, Giovinazzo E, Oesch PA, et al. An Hα view of galaxy buildup in the first 2 Gyr: Luminosity functions at z ∼ 4−6.5 from NIRCam/grism spectroscopy. Astronomy & Astrophysics. 2025;694. doi:10.1051/0004-6361/202452363","mla":"Covelo-Paz, Alba, et al. “An Hα View of Galaxy Buildup in the First 2 Gyr: Luminosity Functions at z ∼ 4−6.5 from NIRCam/Grism Spectroscopy.” Astronomy & Astrophysics, vol. 694, A178, EDP Sciences, 2025, doi:10.1051/0004-6361/202452363."},"OA_place":"publisher","OA_type":"diamond","doi":"10.1051/0004-6361/202452363","arxiv":1,"external_id":{"isi":["001420194600001"],"arxiv":["2409.17241"]},"date_published":"2025-02-12T00:00:00Z","language":[{"iso":"eng"}],"fulldoi":"https://doi.org/10.1051/0004-6361/202452363","ddc":["520"],"has_accepted_license":"1","day":"12","article_processing_charge":"No","type":"journal_article","article_number":"A178","author":[{"last_name":"Covelo-Paz","full_name":"Covelo-Paz, Alba","first_name":"Alba"},{"last_name":"Giovinazzo","first_name":"Emma","full_name":"Giovinazzo, Emma"},{"full_name":"Oesch, Pascal A.","first_name":"Pascal A.","last_name":"Oesch"},{"first_name":"Romain A.","full_name":"Meyer, Romain A.","last_name":"Meyer"},{"last_name":"Weibel","full_name":"Weibel, Andrea","first_name":"Andrea"},{"first_name":"Gabriel","full_name":"Brammer, Gabriel","last_name":"Brammer"},{"last_name":"Fudamoto","full_name":"Fudamoto, Yoshinobu","first_name":"Yoshinobu"},{"last_name":"Kerutt","full_name":"Kerutt, Josephine","first_name":"Josephine"},{"first_name":"Jamie","full_name":"Lin, Jamie","last_name":"Lin"},{"last_name":"Matharu","first_name":"Jasleen","full_name":"Matharu, Jasleen"},{"last_name":"Naidu","first_name":"Rohan P.","full_name":"Naidu, Rohan P."},{"last_name":"Velichko","first_name":"Anna","full_name":"Velichko, Anna"},{"last_name":"Bollo","first_name":"Victoria","full_name":"Bollo, Victoria"},{"full_name":"Bouwens, Rychard","first_name":"Rychard","last_name":"Bouwens"},{"last_name":"Chisholm","full_name":"Chisholm, John","first_name":"John"},{"last_name":"Illingworth","full_name":"Illingworth, Garth D.","first_name":"Garth D."},{"orcid":"0000-0001-5346-6048","last_name":"Kramarenko","id":"9a9394cb-3200-11ee-973b-f5ba2a8b16e4","first_name":"Ivan","full_name":"Kramarenko, Ivan"},{"first_name":"Daniel","full_name":"Magee, Daniel","last_name":"Magee"},{"last_name":"Maseda","first_name":"Michael","full_name":"Maseda, Michael"},{"full_name":"Matthee, Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720","first_name":"Jorryt J","last_name":"Matthee","orcid":"0000-0003-2871-127X"},{"full_name":"Nelson, Erica","first_name":"Erica","last_name":"Nelson"},{"full_name":"Reddy, Naveen","first_name":"Naveen","last_name":"Reddy"},{"full_name":"Schaerer, Daniel","first_name":"Daniel","last_name":"Schaerer"},{"last_name":"Stefanon","full_name":"Stefanon, Mauro","first_name":"Mauro"},{"last_name":"Xiao","full_name":"Xiao, Mengyuan","first_name":"Mengyuan"}],"publication_identifier":{"eissn":["1432-0746"],"issn":["0004-6361"]},"scopus_import":"1"},{"_id":"19294","has_accepted_license":"1","ddc":["570"],"month":"03","fulldoi":"https://doi.org/10.15479/AT:ISTA:19294","date_created":"2025-03-04T13:27:21Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"CaGu"},{"_id":"Bio"},{"_id":"FyKo"},{"_id":"GaTk"}],"related_material":{"record":[{"status":"public","id":"19626","relation":"used_in_publication"}]},"date_updated":"2026-05-20T08:33:07Z","file":[{"creator":"dernst","file_name":"Data1.xlsx","file_id":"19295","date_updated":"2025-03-04T13:08:52Z","success":1,"access_level":"open_access","content_type":"application/vnd.openxmlformats-officedocument.spreadsheetml.sheet","date_created":"2025-03-04T13:08:52Z","file_size":269054,"checksum":"11a5bab307a4e1e1598a1577d8a2fbb5","relation":"main_file"},{"relation":"main_file","checksum":"3b057894322639f0c1e11fb2e84173e6","file_size":87143,"date_created":"2025-03-04T13:08:52Z","content_type":"application/vnd.openxmlformats-officedocument.spreadsheetml.sheet","access_level":"open_access","success":1,"file_id":"19296","date_updated":"2025-03-04T13:08:52Z","file_name":"Data2.xlsx","creator":"dernst"},{"file_name":"Data3.xlsx","creator":"dernst","success":1,"file_id":"19297","date_updated":"2025-03-04T13:08:52Z","access_level":"open_access","date_created":"2025-03-04T13:08:52Z","content_type":"application/vnd.openxmlformats-officedocument.spreadsheetml.sheet","file_size":129101,"checksum":"a551e1b79a138bb97ab96979aa475b3c","relation":"main_file"},{"success":1,"file_id":"19298","date_updated":"2025-03-04T13:08:52Z","file_name":"Data4.xlsx","creator":"dernst","file_size":86243,"checksum":"d6909c9bf111f859058082b1a2f970c4","relation":"main_file","access_level":"open_access","date_created":"2025-03-04T13:08:52Z","content_type":"application/vnd.openxmlformats-officedocument.spreadsheetml.sheet"},{"success":1,"date_updated":"2025-03-04T13:08:52Z","file_id":"19299","file_name":"Data5.xlsx","creator":"dernst","file_size":26049,"checksum":"e5725a3a118a3f06846104906c8792c7","relation":"main_file","access_level":"open_access","date_created":"2025-03-04T13:08:52Z","content_type":"application/vnd.openxmlformats-officedocument.spreadsheetml.sheet"},{"success":1,"file_id":"19300","date_updated":"2025-03-04T13:08:52Z","creator":"dernst","file_name":"RawData_2_3.xlsx","checksum":"16763c127049f14bd587dc885677dce1","file_size":7327253,"relation":"main_file","access_level":"open_access","date_created":"2025-03-04T13:08:52Z","content_type":"application/vnd.openxmlformats-officedocument.spreadsheetml.sheet"},{"success":1,"file_id":"19301","date_updated":"2025-03-05T07:39:38Z","file_name":"Readme.txt","creator":"dernst","relation":"main_file","checksum":"2f3e1a368b4e3abc46bf37e02724f0f4","file_size":606,"date_created":"2025-03-05T07:39:38Z","content_type":"text/plain","access_level":"open_access"}],"oa":1,"oa_version":"Published 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C","full_name":"Guet, Calin C"}],"OA_type":"gold","citation":{"ama":"Jain K, Hauschild R, Bochkareva O, Römhild R, Tkačik G, Guet CC. Data for “Pulsatile basal gene expression as a fitness determinant in bacteria.” 2025. doi:10.15479/AT:ISTA:19294","mla":"Jain, Kirti, et al. Data for “Pulsatile Basal Gene Expression as a Fitness Determinant in Bacteria.” Institute of Science and Technology Austria, 2025, doi:10.15479/AT:ISTA:19294.","ista":"Jain K, Hauschild R, Bochkareva O, Römhild R, Tkačik G, Guet CC. 2025. Data for ‘Pulsatile basal gene expression as a fitness determinant in bacteria’, Institute of Science and Technology Austria, 10.15479/AT:ISTA:19294.","short":"K. Jain, R. Hauschild, O. Bochkareva, R. Römhild, G. Tkačik, C.C. Guet, (2025).","ieee":"K. Jain, R. Hauschild, O. Bochkareva, R. Römhild, G. Tkačik, and C. C. Guet, “Data for ‘Pulsatile basal gene expression as a fitness determinant in bacteria.’” Institute of Science and Technology Austria, 2025.","chicago":"Jain, Kirti, Robert Hauschild, Olga Bochkareva, Roderich Römhild, Gašper Tkačik, and Calin C Guet. “Data for ‘Pulsatile Basal Gene Expression as a Fitness Determinant in Bacteria.’” Institute of Science and Technology Austria, 2025. https://doi.org/10.15479/AT:ISTA:19294.","apa":"Jain, K., Hauschild, R., Bochkareva, O., Römhild, R., Tkačik, G., & Guet, C. C. (2025). Data for “Pulsatile basal gene expression as a fitness determinant in bacteria.” Institute of Science and Technology Austria. https://doi.org/10.15479/AT:ISTA:19294"},"corr_author":"1","OA_place":"repository","year":"2025","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"type":"research_data","title":"Data for \"Pulsatile basal gene expression as a fitness determinant in bacteria\"","abstract":[{"text":"Active regulation of gene expression, orchestrated by complex interactions of activators and repressors at promoters, controls the fate of organisms. In contrast, basal expression at uninduced promoters is considered to be a dynamically inert mode of non-functional “promoter leakiness”, merely a byproduct of transcriptional regulation. Here, we investigate the basal expression mode of the mar operon, the main regulator of intrinsic multiple antibiotic resistance in Escherichia coli, and link its dynamic properties to the non-canonical, yet highly conserved start codon of marR across Enterobacteriaceae. Real-time, single-cell measurements across tens of generations reveal that basal expression consists of rare stochastic gene expression pulses, which maximize variability in wildtype and, surprisingly, transiently accelerate cellular elongation rates. Competition experiments show that basal expression confers fitness advantages to wildtype across several transitions between exponential and stationary growth by shortening lag times. The dynamically rich basal expression of the mar operon has likely been evolutionarily maintained for its role in growth homeostasis of Enterobacteria within the gut environment, thereby allowing other ancillary gene regulatory roles to evolve, e.g. control of costly-to-induce multi-drug efflux pumps. Understanding the complex selection forces governing genetic systems involved in intrinsic multi-drug resistance is crucial for effective public health measures.","lang":"eng"}],"article_processing_charge":"No","status":"public","publisher":"Institute of Science and Technology Austria","day":"04"},{"external_id":{"isi":["001514422600026"],"pmid":["39977506"]},"pmid":1,"date_published":"2025-02-20T00:00:00Z","language":[{"iso":"eng"}],"fulldoi":"https://doi.org/10.1126/science.ads0426","day":"20","type":"journal_article","acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"LifeSc"},{"_id":"M-Shop"},{"_id":"NanoFab"}],"article_processing_charge":"No","corr_author":"1","page":"845-850","scopus_import":"1","publication_identifier":{"eissn":["1095-9203"]},"author":[{"first_name":"Shengduo","id":"12ab8624-4c8a-11ec-9e11-e1ac2438f22f","full_name":"Xu, Shengduo","last_name":"Xu"},{"id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc","first_name":"Sharona","full_name":"Horta, Sharona","last_name":"Horta"},{"id":"5bdaf946-5355-11ee-ae5a-8061700bd605","first_name":"Abayomi Q","full_name":"Lawal, Abayomi Q","last_name":"Lawal"},{"last_name":"Maji","full_name":"Maji, Krishnendu","first_name":"Krishnendu","id":"76bc9e9f-ba0b-11ee-8184-90edabd17a58"},{"first_name":"Magali","id":"bc07ac4d-142e-11eb-a9d5-d72db792859d","full_name":"Lorion, Magali","last_name":"Lorion"},{"full_name":"Ibáñez, Maria","first_name":"Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87","last_name":"Ibáñez","orcid":"0000-0001-5013-2843"}],"publication":"Science","oa_version":"None","intvolume":" 387","related_material":{"link":[{"description":"News on ISTA website","url":"https://ista.ac.at/en/news/cooling-materials-out-of-the-3d-printer/","relation":"press_release"}]},"date_updated":"2026-04-28T13:43:53Z","isi":1,"date_created":"2025-03-09T23:01:26Z","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","department":[{"_id":"MaIb"}],"article_type":"original","_id":"19364","month":"02","quality_controlled":"1","issue":"6736","status":"public","publisher":"AAAS","project":[{"name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery","_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A"}],"acknowledgement":"This work was supported by the Scientific Service Units (SSU) of ISTA through resources provided by the Electron Microscopy Facility (EMF), the Lab Support Facility (LSF), the Communication & Events facility, the Miba Machine Shop, and the Nanofabrication Facility (NNF). The Mechanical Response of Materials (MRM) Service Unit of the Technical University of Wien is acknowledged for Mechanical tests. X. L. Yan and S. Bühler-Paschen (Institute of Solid-State Physics, Technical University of Wien) are acknowledged for granting us access to their equipment, which allowed us to perform independent corroborative measurements. M. Qin is acknowledged for help with Au deposition and wire bonding for samples used for PPMS measurements. The lab of B. Hof and Z. Lu is acknowledged for help with rheological properties measurements. The members of the Ibáñez research group, especially N. Jakhar, C. Fiedler, and T. Kleinhanns, are acknowledged for their feedback on the manuscript and fruitful discussions. This work was financially supported by ISTA and the Werner Siemens Foundation.","abstract":[{"text":"Thermoelectric coolers (TECs) are pivotal in modern heat management but face limitations in efficiency and manufacturing scalability. We address these challenges by using an extrusion-based 3D printing technique to fabricate high-performance thermoelectric materials. Our ink formulations ensure the integrity of the 3D-printed structure and effective particle bonding during sintering, achieving record-high figure of merit (zT) values of 1.42 for p-type bismuth antimony telluride [(Bi,Sb)2Te3] and 1.3 for n-type silver selenide (Ag2Se) materials at room temperature. The resulting TEC demonstrates a cooling temperature gradient of 50°C in air. Moreover, this scalable and cost-effective method circumvents energy-intensive and time-consuming steps, such as ingot preparation and subsequently machining processes, offering a transformative solution for thermoelectric device production and heralding a new era of efficient and sustainable thermoelectric technologies.","lang":"eng"}],"title":"Interfacial bonding enhances thermoelectric cooling in 3D-printed materials","citation":{"apa":"Xu, S., Horta, S., Lawal, A. Q., Maji, K., Lorion, M., & Ibáñez, M. (2025). Interfacial bonding enhances thermoelectric cooling in 3D-printed materials. Science. AAAS. https://doi.org/10.1126/science.ads0426","chicago":"Xu, Shengduo, Sharona Horta, Abayomi Q Lawal, Krishnendu Maji, Magali Lorion, and Maria Ibáñez. “Interfacial Bonding Enhances Thermoelectric Cooling in 3D-Printed Materials.” Science. AAAS, 2025. https://doi.org/10.1126/science.ads0426.","ieee":"S. Xu, S. Horta, A. Q. Lawal, K. Maji, M. Lorion, and M. Ibáñez, “Interfacial bonding enhances thermoelectric cooling in 3D-printed materials,” Science, vol. 387, no. 6736. AAAS, pp. 845–850, 2025.","short":"S. Xu, S. Horta, A.Q. Lawal, K. Maji, M. Lorion, M. Ibáñez, Science 387 (2025) 845–850.","ista":"Xu S, Horta S, Lawal AQ, Maji K, Lorion M, Ibáñez M. 2025. Interfacial bonding enhances thermoelectric cooling in 3D-printed materials. Science. 387(6736), 845–850.","mla":"Xu, Shengduo, et al. “Interfacial Bonding Enhances Thermoelectric Cooling in 3D-Printed Materials.” Science, vol. 387, no. 6736, AAAS, 2025, pp. 845–50, doi:10.1126/science.ads0426.","ama":"Xu S, Horta S, Lawal AQ, Maji K, Lorion M, Ibáñez M. Interfacial bonding enhances thermoelectric cooling in 3D-printed materials. Science. 2025;387(6736):845-850. doi:10.1126/science.ads0426"},"publication_status":"published","volume":387,"year":"2025","doi":"10.1126/science.ads0426","OA_type":"closed access"},{"type":"journal_article","article_processing_charge":"Yes","day":"20","publication_identifier":{"eissn":["1538-4357"],"issn":["0004-637X"]},"scopus_import":"1","author":[{"first_name":"Eshita","full_name":"Banerjee, Eshita","last_name":"Banerjee"},{"last_name":"Muzahid","full_name":"Muzahid, Sowgat","first_name":"Sowgat"},{"first_name":"Joop","full_name":"Schaye, Joop","last_name":"Schaye"},{"last_name":"Blaizot","first_name":"Jérémy","full_name":"Blaizot, Jérémy"},{"first_name":"Nicolas","full_name":"Bouché, Nicolas","last_name":"Bouché"},{"last_name":"Cantalupo","first_name":"Sebastiano","full_name":"Cantalupo, Sebastiano"},{"first_name":"Sean D.","full_name":"Johnson, Sean D.","last_name":"Johnson"},{"first_name":"Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720","full_name":"Matthee, Jorryt J","last_name":"Matthee","orcid":"0000-0003-2871-127X"},{"first_name":"Anne","full_name":"Verhamme, Anne","last_name":"Verhamme"}],"article_number":"171","language":[{"iso":"eng"}],"external_id":{"isi":["001421001500001"]},"date_published":"2025-02-20T00:00:00Z","has_accepted_license":"1","ddc":["520"],"fulldoi":"https://doi.org/10.3847/1538-4357/ada7e9","acknowledgement":"We would like to thank the anonymous referee for useful comments. We thank Marijke Segers, Lorrie Straka, and Monica Turner for their early contributions to the MUSEQuBES project. We thank Raghunathan Srianand for useful suggestions. E.B. thanks Labanya Kumar Guha and Yucheng Guo for helpful discussions. S.C. gratefully acknowledges the fund support from the European Research Council (ERC).\r\n\r\nSoftware: NumPy (C. R. Harris et al. 2020), SciPy (P. Virtanen et al. 2020), Matplotlib (J. D. Hunter 2007), and AstroPy (Astropy Collaboration et al. 2013, 2018).","abstract":[{"lang":"eng","text":"We present a comprehensive analysis of H i absorption around 96 Lyα emitters (LAEs) at z ≈ 3.3 (median Lyα luminosity ≈1042 erg s−1). These LAEs were identified within eight MUSE fields, each (math. formular) on the sky and centered on a bright background quasar, as part of the MUSEQuBES survey. Using Voigt profile fitting for all H i absorbers detected within ±500 km s−1 of these LAEs, we compiled a catalog of 800 H i absorption components. Our analysis shows that H i absorption is enhanced near the LAEs compared to the intergalactic medium. However, no trend is found between the column densities of H i absorbers and their impact parameters from the LAEs (spanning ≈54–260 pkpc). Additionally, all galaxies associated with Lyman-limit systems have impact parameters >50 pkpc from the quasar sightlines, suggesting that true absorber hosts may be too faint to detect. The LAEs show an overall H i covering fraction (fc(H i)) of ≈88% for a threshold (math. formular) (H i) = 15. Notably, at the same threshold, the LAEs in pairs/groups exhibit a 100% H i covering fraction out to ≈250 pkpc. In contrast, isolated LAEs consistently show a lower fc(H i) of ≈80%. This environmental influence on fc(H i) is also evident up to ≈300 km s−1 in differential bins of line-of-sight velocity. We find an anticorrelation between fc(H i) and the equivalent width of rest-frame Lyα emission (EW0). Based on the Lyα shell model, this could imply that gas-rich galaxies tend to reside in gas-rich environments or that the LAEs with higher EW0 are more efficient at ionizing their surrounding medium."}],"title":"MUSEQuBES: Connecting H i Absorption with Lyα emitters at z ≈ 3.3","quality_controlled":"1","status":"public","issue":"2","publisher":"IOP Publishing","doi":"10.3847/1538-4357/ada7e9","OA_type":"gold","citation":{"ieee":"E. Banerjee et al., “MUSEQuBES: Connecting H i Absorption with Lyα emitters at z ≈ 3.3,” The Astrophysical Journal, vol. 980, no. 2. IOP Publishing, 2025.","short":"E. Banerjee, S. Muzahid, J. Schaye, J. Blaizot, N. Bouché, S. Cantalupo, S.D. Johnson, J.J. Matthee, A. Verhamme, The Astrophysical Journal 980 (2025).","apa":"Banerjee, E., Muzahid, S., Schaye, J., Blaizot, J., Bouché, N., Cantalupo, S., … Verhamme, A. (2025). MUSEQuBES: Connecting H i Absorption with Lyα emitters at z ≈ 3.3. The Astrophysical Journal. IOP Publishing. https://doi.org/10.3847/1538-4357/ada7e9","chicago":"Banerjee, Eshita, Sowgat Muzahid, Joop Schaye, Jérémy Blaizot, Nicolas Bouché, Sebastiano Cantalupo, Sean D. Johnson, Jorryt J Matthee, and Anne Verhamme. “MUSEQuBES: Connecting H i Absorption with Lyα Emitters at z ≈ 3.3.” The Astrophysical Journal. IOP Publishing, 2025. https://doi.org/10.3847/1538-4357/ada7e9.","mla":"Banerjee, Eshita, et al. “MUSEQuBES: Connecting H i Absorption with Lyα Emitters at z ≈ 3.3.” The Astrophysical Journal, vol. 980, no. 2, 171, IOP Publishing, 2025, doi:10.3847/1538-4357/ada7e9.","ama":"Banerjee E, Muzahid S, Schaye J, et al. MUSEQuBES: Connecting H i Absorption with Lyα emitters at z ≈ 3.3. The Astrophysical Journal. 2025;980(2). doi:10.3847/1538-4357/ada7e9","ista":"Banerjee E, Muzahid S, Schaye J, Blaizot J, Bouché N, Cantalupo S, Johnson SD, Matthee JJ, Verhamme A. 2025. MUSEQuBES: Connecting H i Absorption with Lyα emitters at z ≈ 3.3. The Astrophysical Journal. 980(2), 171."},"publication_status":"published","OA_place":"publisher","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"volume":980,"year":"2025","file":[{"success":1,"file_id":"19379","date_updated":"2025-03-10T11:54:52Z","creator":"dernst","file_name":"2025_AstrophysicalJour_Banerjee.pdf","checksum":"1d33a8eb59f42a0c7a943c8859e9b883","file_size":1194131,"relation":"main_file","access_level":"open_access","date_created":"2025-03-10T11:54:52Z","content_type":"application/pdf"}],"date_updated":"2026-02-16T12:42:00Z","isi":1,"oa":1,"publication":"The Astrophysical Journal","oa_version":"Published Version","file_date_updated":"2025-03-10T11:54:52Z","intvolume":" 980","_id":"19365","DOAJ_listed":"1","month":"02","date_created":"2025-03-09T23:01:26Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"JoMa"}],"article_type":"original"},{"quality_controlled":"1","publisher":"Springer Nature","status":"public","acknowledgement":"The authors thank Michele Guastalla for his contributions to the boMdM analyses and Stephan Handschin from the Scientific Center for Optical and Electron Microscopy (ScopeM) of ETH Zurich for the TEM imaging. We gratefully acknowledge the Functional Genomics Center Zurich (FGCZ) for performing the mass spectrometry analysis for this study.\r\nOpen access funding provided by Swiss Federal Institute of Technology Zurich. This work was supported by basic funding from ETH Zurich.","title":"Mastitis-related Staphylococcus aureus-derived extracellular vesicles induce a pro-inflammatory response in bovine monocyte-derived macrophages","abstract":[{"text":"Staphylococcus aureus (S. aureus) is one of the most common causative agents of mammary gland infection and mastitis, but the specific role of S. aureus-derived extracellular vesicles (SaEVs) in mastitis has been poorly studied to date. Here, we aimed to investigate the response of bovine monocyte-derived macrophages (boMdM) to SaEVs of the genotype B (GTB) mastitis-related strain M5512B. Specifically, we evaluated the effects on the actin cytoskeleton, gene expression, and the SaEV proteomic cargo. Furthermore, we assessed to what extent the cellular and molecular response of boMdM to SaEVs differed from peripheral mononuclear blood cells (PBMCs) used for in vitro derivation of the former. We observed that SaEVs induced morphological changes in boMdM, leading to a pro-inflammatory and pyroptosis-related increased gene expression. Additionally, our study revealed that boMdM and PBMCs exhibited stimulus-specific differing responses. The proteomic analysis of SaEVs identified clusters of proteins related to virulence and antibiotic resistance, supporting the theory that S. aureus might use EVs to evade host defences and colonize the mammary gland. Our results bring new insights into how SaEVs might impact the host during an S. aureus infection, which can be useful for future S. aureus vaccine development.","lang":"eng"}],"OA_place":"publisher","publication_status":"published","citation":{"apa":"Saenz-De-Juano, M. D., Silvestrelli, G., Buri, S., Zinsli, L. V., Schmelcher, M., & Ulbrich, S. E. (2025). Mastitis-related Staphylococcus aureus-derived extracellular vesicles induce a pro-inflammatory response in bovine monocyte-derived macrophages. Scientific Reports. Springer Nature. https://doi.org/10.1038/s41598-025-90466-6","chicago":"Saenz-De-Juano, Mara D., Giulia Silvestrelli, Samuel Buri, Léa V. Zinsli, Mathias Schmelcher, and Susanne E. Ulbrich. “Mastitis-Related Staphylococcus Aureus-Derived Extracellular Vesicles Induce a pro-Inflammatory Response in Bovine Monocyte-Derived Macrophages.” Scientific Reports. Springer Nature, 2025. https://doi.org/10.1038/s41598-025-90466-6.","ieee":"M. D. Saenz-De-Juano, G. Silvestrelli, S. Buri, L. V. Zinsli, M. Schmelcher, and S. E. Ulbrich, “Mastitis-related Staphylococcus aureus-derived extracellular vesicles induce a pro-inflammatory response in bovine monocyte-derived macrophages,” Scientific Reports, vol. 15. Springer Nature, p. 6059, 2025.","short":"M.D. Saenz-De-Juano, G. Silvestrelli, S. Buri, L.V. Zinsli, M. Schmelcher, S.E. Ulbrich, Scientific Reports 15 (2025) 6059.","ista":"Saenz-De-Juano MD, Silvestrelli G, Buri S, Zinsli LV, Schmelcher M, Ulbrich SE. 2025. Mastitis-related Staphylococcus aureus-derived extracellular vesicles induce a pro-inflammatory response in bovine monocyte-derived macrophages. Scientific Reports. 15, 6059.","mla":"Saenz-De-Juano, Mara D., et al. “Mastitis-Related Staphylococcus Aureus-Derived Extracellular Vesicles Induce a pro-Inflammatory Response in Bovine Monocyte-Derived Macrophages.” Scientific Reports, vol. 15, Springer Nature, 2025, p. 6059, doi:10.1038/s41598-025-90466-6.","ama":"Saenz-De-Juano MD, Silvestrelli G, Buri S, Zinsli LV, Schmelcher M, Ulbrich SE. Mastitis-related Staphylococcus aureus-derived extracellular vesicles induce a pro-inflammatory response in bovine monocyte-derived macrophages. Scientific Reports. 2025;15:6059. doi:10.1038/s41598-025-90466-6"},"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"year":"2025","volume":15,"doi":"10.1038/s41598-025-90466-6","OA_type":"gold","publication":"Scientific Reports","oa_version":"Published Version","intvolume":" 15","file_date_updated":"2025-03-10T12:00:34Z","oa":1,"isi":1,"file":[{"content_type":"application/pdf","date_created":"2025-03-10T12:00:34Z","access_level":"open_access","relation":"main_file","checksum":"51b55ae299de1fa126016a11024b499a","file_size":2780316,"creator":"dernst","file_name":"2025_ScientificReports_SaenzdeJuano.pdf","file_id":"19380","date_updated":"2025-03-10T12:00:34Z","success":1}],"date_updated":"2025-09-30T10:58:59Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","date_created":"2025-03-09T23:01:26Z","article_type":"original","department":[{"_id":"LoSw"}],"DOAJ_listed":"1","_id":"19366","month":"02","day":"19","type":"journal_article","article_processing_charge":"Yes","page":"6059","publication_identifier":{"eissn":["2045-2322"]},"scopus_import":"1","author":[{"last_name":"Saenz-De-Juano","first_name":"Mara D.","full_name":"Saenz-De-Juano, Mara D."},{"full_name":"Silvestrelli, Giulia","id":"12632ae8-799e-11ef-94a2-e5a3b5ef49e9","first_name":"Giulia","last_name":"Silvestrelli"},{"last_name":"Buri","first_name":"Samuel","full_name":"Buri, Samuel"},{"first_name":"Léa V.","full_name":"Zinsli, Léa V.","last_name":"Zinsli"},{"last_name":"Schmelcher","full_name":"Schmelcher, Mathias","first_name":"Mathias"},{"last_name":"Ulbrich","first_name":"Susanne E.","full_name":"Ulbrich, Susanne E."}],"pmid":1,"external_id":{"pmid":["39972051"],"isi":["001426697000031"]},"date_published":"2025-02-19T00:00:00Z","language":[{"iso":"eng"}],"has_accepted_license":"1","fulldoi":"https://doi.org/10.1038/s41598-025-90466-6","ddc":["570"]},{"scopus_import":"1","publication_identifier":{"eissn":["1532-2548"]},"author":[{"last_name":"De Jaeger-Braet","id":"26bd38d3-c59a-11ee-a1af-d7a988cafcc5","first_name":"Joke G","full_name":"De Jaeger-Braet, Joke G"}],"corr_author":"1","article_number":"kiaf055","type":"journal_article","PlanS_conform":"1","article_processing_charge":"Yes (in subscription journal)","day":"07","has_accepted_license":"1","ddc":["580"],"fulldoi":"https://doi.org/10.1093/plphys/kiaf055","language":[{"iso":"eng"}],"date_published":"2025-02-07T00:00:00Z","pmid":1,"external_id":{"pmid":["39938057"],"isi":["001427994500001"]},"doi":"10.1093/plphys/kiaf055","OA_type":"hybrid","publication_status":"published","OA_place":"publisher","citation":{"chicago":"De Jaeger-Braet, Joke G. “Arabidopsis Accessions and Their Difference in Heat Tolerance during Meiosis.” Plant Physiology. Oxford University Press, 2025. https://doi.org/10.1093/plphys/kiaf055.","apa":"De Jaeger-Braet, J. G. (2025). Arabidopsis accessions and their difference in heat tolerance during meiosis. Plant Physiology. Oxford University Press. https://doi.org/10.1093/plphys/kiaf055","short":"J.G. De Jaeger-Braet, Plant Physiology 197 (2025).","ieee":"J. G. De Jaeger-Braet, “Arabidopsis accessions and their difference in heat tolerance during meiosis,” Plant Physiology, vol. 197, no. 2. Oxford University Press, 2025.","ista":"De Jaeger-Braet JG. 2025. Arabidopsis accessions and their difference in heat tolerance during meiosis. Plant Physiology. 197(2), kiaf055.","ama":"De Jaeger-Braet JG. Arabidopsis accessions and their difference in heat tolerance during meiosis. Plant Physiology. 2025;197(2). doi:10.1093/plphys/kiaf055","mla":"De Jaeger-Braet, Joke G. “Arabidopsis Accessions and Their Difference in Heat Tolerance during Meiosis.” Plant Physiology, vol. 197, no. 2, kiaf055, Oxford University Press, 2025, doi:10.1093/plphys/kiaf055."},"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"volume":197,"year":"2025","title":"Arabidopsis accessions and their difference in heat tolerance during meiosis","quality_controlled":"1","status":"public","issue":"2","publisher":"Oxford University Press","_id":"19367","month":"02","date_created":"2025-03-09T23:01:27Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","department":[{"_id":"XiFe"}],"article_type":"original","date_updated":"2025-09-30T10:48:08Z","file":[{"creator":"dernst","file_name":"2025_PlantPhysiology_deJaegerBraet.pdf","success":1,"file_id":"19570","date_updated":"2025-04-16T07:25:21Z","access_level":"open_access","date_created":"2025-04-16T07:25:21Z","content_type":"application/pdf","checksum":"28e18fd7d00c74782f4f42501ecd4aae","file_size":320184,"relation":"main_file"}],"isi":1,"oa":1,"oa_version":"Published Version","publication":"Plant Physiology","file_date_updated":"2025-04-16T07:25:21Z","intvolume":" 197"},{"article_number":"e2024WR037766","scopus_import":"1","publication_identifier":{"eissn":["1944-7973"],"issn":["0043-1397"]},"author":[{"first_name":"N.","full_name":"Bulovic, N.","last_name":"Bulovic"},{"last_name":"Johnson","full_name":"Johnson, F.","first_name":"F."},{"last_name":"Lievens","first_name":"H.","full_name":"Lievens, H."},{"last_name":"Shaw","orcid":"0000-0001-7640-6152","full_name":"Shaw, Thomas","first_name":"Thomas","id":"3caa3f91-1f03-11ee-96ce-e0e553054d6e"},{"last_name":"Mcphee","full_name":"Mcphee, J.","first_name":"J."},{"last_name":"Gascoin","full_name":"Gascoin, S.","first_name":"S."},{"last_name":"Demuzere","full_name":"Demuzere, M.","first_name":"M."},{"last_name":"Mcintyre","full_name":"Mcintyre, N.","first_name":"N."}],"day":"01","type":"journal_article","article_processing_charge":"Yes (via OA deal)","PlanS_conform":"1","has_accepted_license":"1","fulldoi":"https://doi.org/10.1029/2024WR037766","ddc":["550"],"external_id":{"isi":["001419509100001"]},"date_published":"2025-02-01T00:00:00Z","language":[{"iso":"eng"}],"publication_status":"published","citation":{"ista":"Bulovic N, Johnson F, Lievens H, Shaw T, Mcphee J, Gascoin S, Demuzere M, Mcintyre N. 2025. Evaluating the performance of sentinel-1 SAR derived snow depth retrievals over the extratropical Andes cordillera. Water Resources Research. 61(2), e2024WR037766.","ama":"Bulovic N, Johnson F, Lievens H, et al. Evaluating the performance of sentinel-1 SAR derived snow depth retrievals over the extratropical Andes cordillera. Water Resources Research. 2025;61(2). doi:10.1029/2024WR037766","mla":"Bulovic, N., et al. “Evaluating the Performance of Sentinel-1 SAR Derived Snow Depth Retrievals over the Extratropical Andes Cordillera.” Water Resources Research, vol. 61, no. 2, e2024WR037766, Wiley, 2025, doi:10.1029/2024WR037766.","chicago":"Bulovic, N., F. Johnson, H. Lievens, Thomas Shaw, J. Mcphee, S. Gascoin, M. Demuzere, and N. Mcintyre. “Evaluating the Performance of Sentinel-1 SAR Derived Snow Depth Retrievals over the Extratropical Andes Cordillera.” Water Resources Research. Wiley, 2025. https://doi.org/10.1029/2024WR037766.","apa":"Bulovic, N., Johnson, F., Lievens, H., Shaw, T., Mcphee, J., Gascoin, S., … Mcintyre, N. (2025). Evaluating the performance of sentinel-1 SAR derived snow depth retrievals over the extratropical Andes cordillera. Water Resources Research. Wiley. https://doi.org/10.1029/2024WR037766","short":"N. Bulovic, F. Johnson, H. Lievens, T. Shaw, J. Mcphee, S. Gascoin, M. Demuzere, N. Mcintyre, Water Resources Research 61 (2025).","ieee":"N. Bulovic et al., “Evaluating the performance of sentinel-1 SAR derived snow depth retrievals over the extratropical Andes cordillera,” Water Resources Research, vol. 61, no. 2. Wiley, 2025."},"OA_place":"publisher","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"volume":61,"year":"2025","doi":"10.1029/2024WR037766","OA_type":"gold","quality_controlled":"1","publisher":"Wiley","status":"public","issue":"2","acknowledgement":"This research was supported by the University of Queensland's PhD scholarship program, the Australian Research Council under the Future Fellowship program (Project ID:FT140100977), and the Sustainable Minerals Institute International Centre of Excellence (Chile). Fiona Johnson is supported by a UNSW Scientia Funding and ARC Training Centre in Data Analytics for Resources and Environments(Grant IC190100031). The authors also thank Liliana Pagliero, Maxi Viale and Rodrigo Correa for their support with obtaining the DGA, SNIH, and Codelco data sets, and the PlanetLabs research and education initiative for free imagery. Open access publishing facilitated by The University of Queensland, as part of the Wiley ‐ The University of Queensland agreement via the Council of Australian University Librarians.","abstract":[{"text":"Monitoring and estimating mountain snowpack mass over regional scales is still a challenge because of the inadequacy of observational networks in capturing spatiotemporal variability, and limitations in remotely sensed retrievals. Recent work using C-band synthetic aperture radar (SAR) backscatter data from the Sentinel-1 satellite mission has shown good promise for tracking mountain snow depth over specific northern hemisphere ranges, although the broader potential is still unknown. Here, we extend the new Sentinel-1 based modeling framework beyond the northern hemisphere by only utilizing globally available input data, and evaluate different model parametrization and model performance over the Chilean and Argentine Andes mountains, which contain the largest mountain snowpack in the southern hemisphere. The accuracy of Sentinel-1 snow depth estimates is evaluated against an extensive in situ network available for the region. Satellite-retrieved snow depth is found to have poorer performance across the Andes than observed for northern hemisphere mountain ranges because of greater sensitivity to evergreen forest cover and shallower snowpacks. The algorithm does offer some skill but performance is variable and site-dependent. Algorithm performance is best over regions with limited evergreen forest cover (<15%) and snow depths greater than 0.75 m, although the retrievals over-estimate snow depth across most sites. Systemic errors for specific snow classes and across different snow depths are shown, highlighting specific areas in need of further investigation and development.","lang":"eng"}],"title":"Evaluating the performance of sentinel-1 SAR derived snow depth retrievals over the extratropical Andes cordillera","date_created":"2025-03-09T23:01:27Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","article_type":"original","department":[{"_id":"FrPe"}],"DOAJ_listed":"1","_id":"19369","month":"02","oa_version":"Published Version","publication":"Water Resources Research","intvolume":" 61","file_date_updated":"2025-03-10T08:16:05Z","oa":1,"isi":1,"date_updated":"2025-09-30T10:48:43Z","file":[{"file_id":"19377","date_updated":"2025-03-10T08:16:05Z","success":1,"file_name":"2025_WaterResourcesResearch_Bulovic.pdf","creator":"dernst","file_size":6362563,"checksum":"8ff09dcae2e508fd72aee80300fc40e2","relation":"main_file","access_level":"open_access","content_type":"application/pdf","date_created":"2025-03-10T08:16:05Z"}]},{"title":"Quantum rotor in a two-dimensional mesoscopic Bose gas","abstract":[{"lang":"eng","text":"We investigate a molecular quantum rotor in a two-dimensional Bose-Einstein condensate. The focus is on studying the angulon quasiparticle concept in the crossover from few- to many-body physics. To this end, we formulate the problem in real space and solve it with a mean-field approach in the frame co-rotating with the impurity. We show that the system starts to feature angulon characteristics when the size of the bosonic cloud is large enough to screen the rotor. More importantly, we demonstrate the departure from the angulon picture for large system sizes or large angular momenta where the properties of the system are determined by collective excitations of the Bose gas."}],"acknowledgement":"We thank Fabian Brauneis, Arthur Christianen and Pietro Massignan for useful discussions. M. S. and A. G. V. would like to thank the Institut Henri Poincaré\r\n(UAR 839 CNRS-Sorbonne Université) and the LabEx CARMIN (ANR-10-LABX-59-01) for\r\ntheir support and hospitality during the final stages of completion of this work. M.S.\r\nand M.T. acknowledge the National Science Centre, Poland, within Sonata Bis Grant No.\r\n2020/38/E/ST2/00564. M.L. acknowledges support by the European Research Council (ERC)\r\nStarting Grant No.801770 (ANGULON). M.S. acknowledges the National Science Centre,\r\nPoland, within Preludium Grant No. 2023/49/N/ST2/03820. We gratefully acknowledge\r\nPoland’s high-performance Infrastructure PLGrid ACK Cyfronet AGH for providing computer\r\nfacilities and support within computational grant no PLG/2023/016878.","issue":"2","status":"public","publisher":"SciPost Foundation","project":[{"call_identifier":"H2020","_id":"2688CF98-B435-11E9-9278-68D0E5697425","grant_number":"801770","name":"Angulon: physics and applications of a new quasiparticle"}],"quality_controlled":"1","OA_type":"gold","doi":"10.21468/SciPostPhys.18.2.059","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"year":"2025","volume":18,"OA_place":"publisher","publication_status":"published","citation":{"ista":"Suchorowski M, Badamshina A, Lemeshko M, Tomza M, Volosniev A. 2025. Quantum rotor in a two-dimensional mesoscopic Bose gas. SciPost Physics. 18(2), 059.","mla":"Suchorowski, Michał, et al. “Quantum Rotor in a Two-Dimensional Mesoscopic Bose Gas.” SciPost Physics, vol. 18, no. 2, 059, SciPost Foundation, 2025, doi:10.21468/SciPostPhys.18.2.059.","ama":"Suchorowski M, Badamshina A, Lemeshko M, Tomza M, Volosniev A. Quantum rotor in a two-dimensional mesoscopic Bose gas. SciPost Physics. 2025;18(2). doi:10.21468/SciPostPhys.18.2.059","apa":"Suchorowski, M., Badamshina, A., Lemeshko, M., Tomza, M., & Volosniev, A. (2025). Quantum rotor in a two-dimensional mesoscopic Bose gas. SciPost Physics. SciPost Foundation. https://doi.org/10.21468/SciPostPhys.18.2.059","chicago":"Suchorowski, Michał, Alina Badamshina, Mikhail Lemeshko, Michał Tomza, and Artem Volosniev. “Quantum Rotor in a Two-Dimensional Mesoscopic Bose Gas.” SciPost Physics. SciPost Foundation, 2025. https://doi.org/10.21468/SciPostPhys.18.2.059.","ieee":"M. Suchorowski, A. Badamshina, M. Lemeshko, M. Tomza, and A. Volosniev, “Quantum rotor in a two-dimensional mesoscopic Bose gas,” SciPost Physics, vol. 18, no. 2. SciPost Foundation, 2025.","short":"M. Suchorowski, A. Badamshina, M. Lemeshko, M. Tomza, A. Volosniev, SciPost Physics 18 (2025)."},"file":[{"file_size":1124066,"checksum":"7bed8c68c36d495540491bd0579e33e4","relation":"main_file","access_level":"open_access","content_type":"application/pdf","date_created":"2025-03-10T07:08:21Z","date_updated":"2025-03-10T07:08:21Z","file_id":"19376","success":1,"creator":"dernst","file_name":"2025_SciPostPhys_Suchorowski.pdf"}],"date_updated":"2025-04-14T07:48:55Z","oa":1,"file_date_updated":"2025-03-10T07:08:21Z","intvolume":" 18","oa_version":"Published Version","publication":"SciPost Physics","month":"02","ec_funded":1,"_id":"19371","DOAJ_listed":"1","department":[{"_id":"MiLe"}],"article_type":"original","date_created":"2025-03-09T23:01:28Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"Yes","type":"journal_article","day":"19","author":[{"last_name":"Suchorowski","first_name":"Michał","full_name":"Suchorowski, Michał"},{"full_name":"Badamshina, Alina","first_name":"Alina","last_name":"Badamshina"},{"id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","first_name":"Mikhail","full_name":"Lemeshko, Mikhail","last_name":"Lemeshko","orcid":"0000-0002-6990-7802"},{"full_name":"Tomza, Michał","first_name":"Michał","last_name":"Tomza"},{"id":"37D278BC-F248-11E8-B48F-1D18A9856A87","first_name":"Artem","full_name":"Volosniev, Artem","orcid":"0000-0003-0393-5525","last_name":"Volosniev"}],"scopus_import":"1","publication_identifier":{"eissn":["2542-4653"]},"corr_author":"1","article_number":"059","language":[{"iso":"eng"}],"arxiv":1,"external_id":{"arxiv":["2407.06046"]},"date_published":"2025-02-19T00:00:00Z","ddc":["530"],"fulldoi":"https://doi.org/10.21468/SciPostPhys.18.2.059","has_accepted_license":"1"},{"type":"journal_article","article_processing_charge":"Yes (via OA deal)","PlanS_conform":"1","day":"28","publication_identifier":{"eissn":["1745-2481"],"issn":["1745-2473"]},"scopus_import":"1","author":[{"last_name":"Xue","id":"31D2C804-F248-11E8-B48F-1D18A9856A87","first_name":"Shi-lei","full_name":"Xue, Shi-lei"},{"last_name":"Yang","full_name":"Yang, Qiutan","first_name":"Qiutan"},{"last_name":"Liberali","first_name":"Prisca","full_name":"Liberali, Prisca"},{"id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","first_name":"Edouard B","full_name":"Hannezo, Edouard B","last_name":"Hannezo","orcid":"0000-0001-6005-1561"}],"article_number":"078104","corr_author":"1","language":[{"iso":"eng"}],"external_id":{"pmid":["40248571"],"arxiv":["2403.19900"],"isi":["001434072800001"]},"pmid":1,"date_published":"2025-02-28T00:00:00Z","arxiv":1,"has_accepted_license":"1","fulldoi":"https://doi.org/10.1038/s41567-025-02792-1","ddc":["530"],"acknowledgement":"We thank all members of the Hannezo and Liberali groups for fruitful discussions, as well as C. Schwayer, G. Quintas, L. Capolupo, D. Bruckner and D. Pinheiro for reading the manuscript. We also thank Y. Wu and X. Wu from the Yang group for performing experiments in the last rounds of revision and the So group at the National Institute of Biological Sciences, Beijing, for helping with the light-sheet time-lapse experiments. This work received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme via grant agreement no. 758617 (to P.L.), Swiss National Foundation (SNF) (no. POOP3_157531 to P.L.), the ERC under the European Union’s Horizon 2020 research and innovation programme under grant agreement no. 851288 (to E.H.) and the Austrian Science Fund (FWF) (no. P 31639 to E.H.). This work was supported by the National Natural Science Foundation of China via grant no.3247060387 (to Q.Y.) and the Strategic Priority Research Program of the Chinese Academy of Sciences (no. XDB0820000 to Q.Y.) . Open access funding provided by Institute of Science and Technology (IST Austria).","title":"Mechanochemical bistability of intestinal organoids enables robust morphogenesis","abstract":[{"text":"Reproducible pattern and form generation during embryogenesis is poorly understood. Intestinal organoid morphogenesis involves a number of mechanochemical regulators such as cell-type-specific cytoskeletal forces and osmotically driven lumen volume changes. It is unclear how these forces are coordinated in time and space to ensure robust morphogenesis. Here we show how mechanosensitive feedback on cytoskeletal tension gives rise to morphological bistability in a minimal model of organoid morphogenesis. In the model, lumen volume changes can impact the epithelial shape via both direct mechanical and indirect mechanosensitive mechanisms. We find that both bulged and budded crypt states are possible and dependent on the history of volume changes. We test key modelling assumptions via biophysical and pharmacological experiments to demonstrate how bistability can explain experimental observations, such as the importance of the timing of lumen shrinkage and robustness of the final morphogenetic state to mechanical perturbations. This suggests that bistability arising from feedback between cellular tensions and fluid pressure could be a general mechanism that coordinates multicellular shape changes in developing systems.","lang":"eng"}],"quality_controlled":"1","project":[{"name":"Design Principles of Branching Morphogenesis","grant_number":"851288","_id":"05943252-7A3F-11EA-A408-12923DDC885E","call_identifier":"H2020"},{"name":"Active mechano-chemical description of the cell cytoskeleton","call_identifier":"FWF","grant_number":"P31639","_id":"268294B6-B435-11E9-9278-68D0E5697425"}],"publisher":"Springer Nature","status":"public","doi":"10.1038/s41567-025-02792-1","OA_type":"hybrid","citation":{"ista":"Xue S, Yang Q, Liberali P, Hannezo EB. 2025. Mechanochemical bistability of intestinal organoids enables robust morphogenesis. Nature Physics. 21, 078104.","mla":"Xue, Shi-lei, et al. “Mechanochemical Bistability of Intestinal Organoids Enables Robust Morphogenesis.” Nature Physics, vol. 21, 078104, Springer Nature, 2025, doi:10.1038/s41567-025-02792-1.","ama":"Xue S, Yang Q, Liberali P, Hannezo EB. Mechanochemical bistability of intestinal organoids enables robust morphogenesis. Nature Physics. 2025;21. doi:10.1038/s41567-025-02792-1","apa":"Xue, S., Yang, Q., Liberali, P., & Hannezo, E. B. (2025). Mechanochemical bistability of intestinal organoids enables robust morphogenesis. Nature Physics. Springer Nature. https://doi.org/10.1038/s41567-025-02792-1","chicago":"Xue, Shi-lei, Qiutan Yang, Prisca Liberali, and Edouard B Hannezo. “Mechanochemical Bistability of Intestinal Organoids Enables Robust Morphogenesis.” Nature Physics. Springer Nature, 2025. https://doi.org/10.1038/s41567-025-02792-1.","ieee":"S. Xue, Q. Yang, P. Liberali, and E. B. Hannezo, “Mechanochemical bistability of intestinal organoids enables robust morphogenesis,” Nature Physics, vol. 21. Springer Nature, 2025.","short":"S. Xue, Q. Yang, P. Liberali, E.B. Hannezo, Nature Physics 21 (2025)."},"OA_place":"publisher","publication_status":"published","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"year":"2025","volume":21,"oa":1,"file":[{"success":1,"file_id":"20129","date_updated":"2025-08-05T12:12:03Z","file_name":"2025_NaturePhysics_Xue.pdf","creator":"dernst","checksum":"fb5e59be145b95f9851d3d7c9dbb85e6","file_size":16302436,"relation":"main_file","access_level":"open_access","date_created":"2025-08-05T12:12:03Z","content_type":"application/pdf"}],"isi":1,"date_updated":"2025-09-30T10:47:36Z","publication":"Nature Physics","oa_version":"Published Version","intvolume":" 21","file_date_updated":"2025-08-05T12:12:03Z","_id":"19373","ec_funded":1,"month":"02","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","date_created":"2025-03-09T23:01:28Z","article_type":"original","department":[{"_id":"EdHa"}]},{"language":[{"iso":"eng"}],"date_published":"2025-02-08T00:00:00Z","fulldoi":"https://doi.org/10.1007/s10853-024-10582-y","type":"journal_article","article_processing_charge":"No","day":"08","scopus_import":"1","publication_identifier":{"eissn":["1573-4803"],"issn":["0022-2461"]},"author":[{"first_name":"Saurabh","id":"12d625da-9cb3-11ed-9667-af09d37d3f0a","full_name":"Singh, Saurabh","last_name":"Singh","orcid":"0000-0003-2209-5269"},{"last_name":"Provino","full_name":"Provino, A.","first_name":"A."},{"first_name":"I.","full_name":"Pallecchi, I.","last_name":"Pallecchi"},{"last_name":"Caglieris","first_name":"F.","full_name":"Caglieris, F."},{"last_name":"Mödlinger","full_name":"Mödlinger, M.","first_name":"M."},{"last_name":"Mele","full_name":"Mele, P.","first_name":"P."},{"last_name":"Latronico","first_name":"G.","full_name":"Latronico, G."},{"first_name":"T.","full_name":"Takeuchi, T.","last_name":"Takeuchi"},{"last_name":"Manfrinetti","first_name":"P.","full_name":"Manfrinetti, P."}],"article_number":"100051","date_updated":"2025-03-10T06:53:16Z","oa_version":"None","publication":"Journal of Materials Science","intvolume":" 60","_id":"19374","month":"02","date_created":"2025-03-09T23:01:29Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_type":"original","department":[{"_id":"MaIb"}],"title":"The new PrNi6Si6 intermetallic: From crystal structure to thermal and electrical transport properties across a wide temperature range (2–900 K)","abstract":[{"lang":"eng","text":"In the present study, the new ternary rare earth intermetallic compound PrNi6Si6 has been investigated. This work completes the study of the RNi6Si6 series (R = rare earth). While the RNi6Si6 compounds for R = La and Ce adopt the CeNi6Si6-type (tP52, P4/nbm, No. 125), surprisingly PrNi6Si6 crystallizes in the YNi6Si6 prototype (tP52, P − 4b2, No. 117) as do all the heavier lanthanides (but Lu). The YNi6Si6-type and its homolog CeNi6Si6 are two tetragonal ordered derivative of the cubic NaZn13-type structure. Lattice parameters for PrNi6Si6 are a = 7.7846(1) Å, c = 11.2144(1) Å, with a unit cell volume, Vobs = 679.585(5) Å3. The temperature dependence of the inverse magnetic susceptibility χ−1(T) follows the Curie–Weiss law, with calculated values of the effective magnetic moment (µeff) and Weiss temperature (Θpm) of 3.55 μB and − 4.5 K, respectively. While the observed µeff is very close to the theoretical value of 3.58 µB for the free Pr3+ ions, a negative value of the Weiss temperature suggests antiferromagnetic interactions in PrNi6Si6. Magnetization measurements confirm that PrNi₆Si₆ orders antiferromagnetically (AFM) below a Néel temperature (TN) of 9 K. The Ni atoms contribute negligibly to the magnetic properties of this phase. The specific heat of PrNi₆Si₆ is approximately 0.42 J K − 1 g − 1. Measurements of electric and thermal transport reveal that PrNi₆Si₆ exhibits metallic behavior across a wide temperature range of 2–900 K, accompanied by a relatively low thermal conductivity of around 6 W K − 1 m − 1 at room temperature. Such properties, together with its high-temperature refractory behavior, make PrNi₆Si₆ worthy of consideration in technological applications where fairly good electrical conductivity should be accompanied by a limited thermal conductivity."}],"quality_controlled":"1","publisher":"Springer Nature","status":"public","doi":"10.1007/s10853-024-10582-y","OA_type":"closed access","publication_status":"published","citation":{"ista":"Singh S, Provino A, Pallecchi I, Caglieris F, Mödlinger M, Mele P, Latronico G, Takeuchi T, Manfrinetti P. 2025. The new PrNi6Si6 intermetallic: From crystal structure to thermal and electrical transport properties across a wide temperature range (2–900 K). Journal of Materials Science. 60, 100051.","mla":"Singh, Saurabh, et al. “The New PrNi6Si6 Intermetallic: From Crystal Structure to Thermal and Electrical Transport Properties across a Wide Temperature Range (2–900 K).” Journal of Materials Science, vol. 60, 100051, Springer Nature, 2025, doi:10.1007/s10853-024-10582-y.","ama":"Singh S, Provino A, Pallecchi I, et al. The new PrNi6Si6 intermetallic: From crystal structure to thermal and electrical transport properties across a wide temperature range (2–900 K). Journal of Materials Science. 2025;60. doi:10.1007/s10853-024-10582-y","apa":"Singh, S., Provino, A., Pallecchi, I., Caglieris, F., Mödlinger, M., Mele, P., … Manfrinetti, P. (2025). The new PrNi6Si6 intermetallic: From crystal structure to thermal and electrical transport properties across a wide temperature range (2–900 K). Journal of Materials Science. Springer Nature. https://doi.org/10.1007/s10853-024-10582-y","chicago":"Singh, Saurabh, A. Provino, I. Pallecchi, F. Caglieris, M. Mödlinger, P. Mele, G. Latronico, T. Takeuchi, and P. Manfrinetti. “The New PrNi6Si6 Intermetallic: From Crystal Structure to Thermal and Electrical Transport Properties across a Wide Temperature Range (2–900 K).” Journal of Materials Science. Springer Nature, 2025. https://doi.org/10.1007/s10853-024-10582-y.","ieee":"S. Singh et al., “The new PrNi6Si6 intermetallic: From crystal structure to thermal and electrical transport properties across a wide temperature range (2–900 K),” Journal of Materials Science, vol. 60. Springer Nature, 2025.","short":"S. Singh, A. Provino, I. Pallecchi, F. Caglieris, M. Mödlinger, P. Mele, G. Latronico, T. Takeuchi, P. Manfrinetti, Journal of Materials Science 60 (2025)."},"year":"2025","volume":60},{"acknowledgement":"This research was funded in part by the DFG project 427755713 GOPro, the DFG GRK 2428 (ConVeY), the MUNI Award in Science and Humanities (MUNI/I/1757/2021) of the Grant Agency of Masaryk University, and the EU under MSCA grant agreement 101034413 (IST-BRIDGE).","abstract":[{"text":"Despite the advances in probabilistic model checking, the scalability of the verification methods remains limited. In particular, the state space often becomes extremely large when instantiating parameterized Markov decision processes (MDPs) even with moderate values. Synthesizing policies for such huge MDPs is beyond the reach of available tools. We propose a learning-based approach to obtain a reasonable policy for such huge MDPs.\r\n\r\nThe idea is to generalize optimal policies obtained by model-checking small instances to larger ones using decision-tree learning. Consequently, our method bypasses the need for explicit state-space exploration of large models, providing a practical solution to the state-space explosion problem. We demonstrate the efficacy of our approach by performing extensive experimentation on the relevant models from the quantitative verification benchmark set. The experimental results indicate that our policies perform well, even when the size of the model is orders of magnitude beyond the reach of state-of-the-art analysis tools.","lang":"eng"}],"title":"1–2–3–Go! Policy synthesis for parameterized Markov decision processes via decision-tree learning and generalization","quality_controlled":"1","status":"public","project":[{"call_identifier":"H2020","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program"}],"publisher":"Springer Nature","doi":"10.1007/978-3-031-82703-7_5","OA_type":"green","OA_place":"repository","publication_status":"published","citation":{"apa":"Azeem, M., Chakraborty, D., Kanav, S., Kretinsky, J., Mohagheghi, M., Mohr, S., & Weininger, M. (2025). 1–2–3–Go! Policy synthesis for parameterized Markov decision processes via decision-tree learning and generalization. In 26th International Conference on Verification, Model Checking, and Abstract Interpretation (Vol. 15530, pp. 97–120). Denver, CO, United States: Springer Nature. https://doi.org/10.1007/978-3-031-82703-7_5","chicago":"Azeem, Muqsit, Debraj Chakraborty, Sudeep Kanav, Jan Kretinsky, Mohammadsadegh Mohagheghi, Stefanie Mohr, and Maximilian Weininger. “1–2–3–Go! Policy Synthesis for Parameterized Markov Decision Processes via Decision-Tree Learning and Generalization.” In 26th International Conference on Verification, Model Checking, and Abstract Interpretation, 15530:97–120. Springer Nature, 2025. https://doi.org/10.1007/978-3-031-82703-7_5.","ieee":"M. Azeem et al., “1–2–3–Go! Policy synthesis for parameterized Markov decision processes via decision-tree learning and generalization,” in 26th International Conference on Verification, Model Checking, and Abstract Interpretation, Denver, CO, United States, 2025, vol. 15530, pp. 97–120.","short":"M. Azeem, D. Chakraborty, S. Kanav, J. Kretinsky, M. Mohagheghi, S. Mohr, M. Weininger, in:, 26th International Conference on Verification, Model Checking, and Abstract Interpretation, Springer Nature, 2025, pp. 97–120.","ista":"Azeem M, Chakraborty D, Kanav S, Kretinsky J, Mohagheghi M, Mohr S, Weininger M. 2025. 1–2–3–Go! Policy synthesis for parameterized Markov decision processes via decision-tree learning and generalization. 26th International Conference on Verification, Model Checking, and Abstract Interpretation. VMCAI: Verification, Model Checking, and Abstract Interpretation, LNCS, vol. 15530, 97–120.","mla":"Azeem, Muqsit, et al. “1–2–3–Go! Policy Synthesis for Parameterized Markov Decision Processes via Decision-Tree Learning and Generalization.” 26th International Conference on Verification, Model Checking, and Abstract Interpretation, vol. 15530, Springer Nature, 2025, pp. 97–120, doi:10.1007/978-3-031-82703-7_5.","ama":"Azeem M, Chakraborty D, Kanav S, et al. 1–2–3–Go! Policy synthesis for parameterized Markov decision processes via decision-tree learning and generalization. In: 26th International Conference on Verification, Model Checking, and Abstract Interpretation. Vol 15530. Springer Nature; 2025:97-120. doi:10.1007/978-3-031-82703-7_5"},"year":"2025","volume":15530,"isi":1,"date_updated":"2025-09-30T10:46:54Z","oa":1,"oa_version":"Preprint","publication":"26th International Conference on Verification, Model Checking, and Abstract Interpretation","intvolume":" 15530","ec_funded":1,"_id":"19375","conference":{"start_date":"2025-01-20","location":"Denver, CO, United States","name":"VMCAI: Verification, Model Checking, and Abstract Interpretation","end_date":"2025-01-21"},"month":"01","date_created":"2025-03-09T23:01:29Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","department":[{"_id":"KrCh"}],"type":"conference","article_processing_charge":"No","day":"23","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2410.18293"}],"scopus_import":"1","publication_identifier":{"issn":["0302-9743"],"isbn":["9783031827020"],"eissn":["1611-3349"]},"author":[{"full_name":"Azeem, Muqsit","first_name":"Muqsit","last_name":"Azeem"},{"last_name":"Chakraborty","full_name":"Chakraborty, Debraj","first_name":"Debraj"},{"first_name":"Sudeep","full_name":"Kanav, Sudeep","last_name":"Kanav"},{"last_name":"Kretinsky","orcid":"0000-0002-8122-2881","first_name":"Jan","id":"44CEF464-F248-11E8-B48F-1D18A9856A87","full_name":"Kretinsky, Jan"},{"last_name":"Mohagheghi","full_name":"Mohagheghi, Mohammadsadegh","first_name":"Mohammadsadegh"},{"last_name":"Mohr","full_name":"Mohr, Stefanie","first_name":"Stefanie"},{"last_name":"Weininger","first_name":"Maximilian","id":"02ab0197-cc70-11ed-ab61-918e71f56881","full_name":"Weininger, Maximilian"}],"page":"97-120","language":[{"iso":"eng"}],"external_id":{"arxiv":["2410.18293"],"isi":["001446577100005"]},"alternative_title":["LNCS"],"date_published":"2025-01-23T00:00:00Z","arxiv":1,"fulldoi":"https://doi.org/10.1007/978-3-031-82703-7_5"},{"day":"27","article_processing_charge":"Yes (via OA deal)","type":"journal_article","article_number":"2026","author":[{"first_name":"Andre A.","full_name":"Gu, Andre A.","last_name":"Gu"},{"full_name":"Ucar, Mehmet C","id":"50B2A802-6007-11E9-A42B-EB23E6697425","first_name":"Mehmet C","orcid":"0000-0003-0506-4217","last_name":"Ucar"},{"last_name":"Tran","full_name":"Tran, Peter","first_name":"Peter"},{"full_name":"Prindle, Arthur","first_name":"Arthur","last_name":"Prindle"},{"full_name":"Kamat, Neha P.","first_name":"Neha P.","last_name":"Kamat"},{"first_name":"Jan","full_name":"Steinkühler, Jan","last_name":"Steinkühler"}],"publication_identifier":{"eissn":["2041-1723"]},"scopus_import":"1","external_id":{"isi":["001435269000002"],"pmid":["40016255"]},"date_published":"2025-02-27T00:00:00Z","pmid":1,"language":[{"iso":"eng"}],"fulldoi":"https://doi.org/10.1038/s41467-025-57178-x","ddc":["570"],"has_accepted_license":"1","publisher":"Springer Nature","status":"public","quality_controlled":"1","title":"Remodeling of lipid-foam prototissues by network-wide tension fluctuations induced by active particles","abstract":[{"lang":"eng","text":"Recent advances in the field of bottom-up synthetic biology have led to the development of synthetic cells that mimic some features of real cells, such as division, protein synthesis, or DNA replication. Larger assemblies of synthetic cells may be used to form prototissues. However, existing prototissues are limited by their relatively small lateral dimensions or their lack of remodeling ability. Here, we introduce a lipid-based tissue mimetic that can be easily prepared and functionalized, consisting of a millimeter-sized “lipid-foam” with individual micrometer-sized compartments bound by lipid bilayers. We characterize the structural and mechanical properties of the lipid-foam tissue mimetic, and we demonstrate self-healing capabilities enabled by the fluidity of the lipid bilayers. Upon inclusion of bacteria in the tissue compartments, we observe that the tissue mimetic exhibits network-wide tension fluctuations driven by membrane tension generation by the swimming bacteria. Active tension fluctuations facilitate the fluidization and reorganization of the prototissue, providing a versatile platform for understanding and mimicking biological tissues."}],"acknowledgement":"This research was supported in part by the National Science Foundation under Grant No. 1844336 (J.S.), 2239567 (A.P), and MRSEC DMR-2308691 (A.G., N.P.K.) and the National Institutes of Health under Grant No. 1R35GM147170-01 (A.P). J.S. thanks Reinhard Lipowsky for discussions on stability of foams.\r\nOpen Access funding enabled and organized by Projekt DEAL.","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"year":"2025","volume":16,"OA_place":"publisher","citation":{"ama":"Gu AA, Ucar MC, Tran P, Prindle A, Kamat NP, Steinkühler J. Remodeling of lipid-foam prototissues by network-wide tension fluctuations induced by active particles. Nature Communications. 2025;16. doi:10.1038/s41467-025-57178-x","mla":"Gu, Andre A., et al. “Remodeling of Lipid-Foam Prototissues by Network-Wide Tension Fluctuations Induced by Active Particles.” Nature Communications, vol. 16, 2026, Springer Nature, 2025, doi:10.1038/s41467-025-57178-x.","ista":"Gu AA, Ucar MC, Tran P, Prindle A, Kamat NP, Steinkühler J. 2025. Remodeling of lipid-foam prototissues by network-wide tension fluctuations induced by active particles. Nature Communications. 16, 2026.","short":"A.A. Gu, M.C. Ucar, P. Tran, A. Prindle, N.P. Kamat, J. Steinkühler, Nature Communications 16 (2025).","ieee":"A. A. Gu, M. C. Ucar, P. Tran, A. Prindle, N. P. Kamat, and J. Steinkühler, “Remodeling of lipid-foam prototissues by network-wide tension fluctuations induced by active particles,” Nature Communications, vol. 16. Springer Nature, 2025.","chicago":"Gu, Andre A., Mehmet C Ucar, Peter Tran, Arthur Prindle, Neha P. Kamat, and Jan Steinkühler. “Remodeling of Lipid-Foam Prototissues by Network-Wide Tension Fluctuations Induced by Active Particles.” Nature Communications. Springer Nature, 2025. https://doi.org/10.1038/s41467-025-57178-x.","apa":"Gu, A. A., Ucar, M. C., Tran, P., Prindle, A., Kamat, N. P., & Steinkühler, J. (2025). Remodeling of lipid-foam prototissues by network-wide tension fluctuations induced by active particles. Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-025-57178-x"},"publication_status":"published","OA_type":"gold","doi":"10.1038/s41467-025-57178-x","intvolume":" 16","file_date_updated":"2025-03-17T09:43:27Z","oa_version":"Published Version","publication":"Nature Communications","oa":1,"isi":1,"file":[{"access_level":"open_access","content_type":"application/pdf","date_created":"2025-03-17T09:43:27Z","file_size":2260791,"checksum":"3bbae9b470c639005815342a39e96918","relation":"main_file","creator":"dernst","file_name":"2025_NatureComm_Gu.pdf","file_id":"19411","date_updated":"2025-03-17T09:43:27Z","success":1}],"date_updated":"2025-09-30T10:59:30Z","article_type":"original","department":[{"_id":"EdHa"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","date_created":"2025-03-16T23:01:23Z","month":"02","DOAJ_listed":"1","_id":"19402"},{"corr_author":"1","article_number":"20","scopus_import":"1","publication_identifier":{"issn":["0003-9527"],"eissn":["1432-0673"]},"author":[{"id":"5DA90512-D80F-11E9-8994-2E2EE6697425","first_name":"Barbara","full_name":"Roos, Barbara","last_name":"Roos","orcid":"0000-0002-9071-5880"},{"orcid":"0000-0002-6781-0521","last_name":"Seiringer","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","first_name":"Robert","full_name":"Seiringer, Robert"}],"day":"01","type":"journal_article","article_processing_charge":"Yes (via OA deal)","has_accepted_license":"1","ddc":["510"],"fulldoi":"https://doi.org/10.1007/s00205-025-02088-x","external_id":{"arxiv":["2306.05824"],"pmid":["40041541"],"isi":["001435380100001"]},"pmid":1,"date_published":"2025-04-01T00:00:00Z","arxiv":1,"language":[{"iso":"eng"}],"publication_status":"published","OA_place":"publisher","citation":{"ista":"Roos B, Seiringer R. 2025. BCS critical temperature on half-spaces. Archive for Rational Mechanics and Analysis. 249, 20.","ama":"Roos B, Seiringer R. BCS critical temperature on half-spaces. Archive for Rational Mechanics and Analysis. 2025;249. doi:10.1007/s00205-025-02088-x","mla":"Roos, Barbara, and Robert Seiringer. “BCS Critical Temperature on Half-Spaces.” Archive for Rational Mechanics and Analysis, vol. 249, 20, Springer Nature, 2025, doi:10.1007/s00205-025-02088-x.","chicago":"Roos, Barbara, and Robert Seiringer. “BCS Critical Temperature on Half-Spaces.” Archive for Rational Mechanics and Analysis. Springer Nature, 2025. https://doi.org/10.1007/s00205-025-02088-x.","apa":"Roos, B., & Seiringer, R. (2025). BCS critical temperature on half-spaces. Archive for Rational Mechanics and Analysis. Springer Nature. https://doi.org/10.1007/s00205-025-02088-x","short":"B. Roos, R. Seiringer, Archive for Rational Mechanics and Analysis 249 (2025).","ieee":"B. Roos and R. Seiringer, “BCS critical temperature on half-spaces,” Archive for Rational Mechanics and Analysis, vol. 249. Springer Nature, 2025."},"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"volume":249,"year":"2025","doi":"10.1007/s00205-025-02088-x","OA_type":"hybrid","quality_controlled":"1","status":"public","project":[{"_id":"bda63fe5-d553-11ed-ba76-a16e3d2f256b","grant_number":"I06427","name":"Mathematical Challenges in BCS Theory of Superconductivity"}],"publisher":"Springer Nature","acknowledgement":"Open access funding provided by Institute of Science and Technology (IST Austria). Financial support by the Austrian Science Fund (FWF) through project number I 6427-N (as part of the SFB/TRR 352) is gratefully acknowledged.","title":"BCS critical temperature on half-spaces","abstract":[{"lang":"eng","text":"We study the BCS critical temperature on half-spaces in dimensions d =1, 2, 3 with Dirichlet or Neumann boundary conditions. We prove that the critical temperature on a half-space is strictly higher than on Rd, at least at weak coupling in d = 1, 2 and weak coupling and small chemical potential in d = 3. Furthermore, we show that the relative shift in critical temperature vanishes in the weak coupling limit."}],"date_created":"2025-03-16T23:01:24Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","department":[{"_id":"RoSe"}],"article_type":"original","_id":"19403","month":"04","publication":"Archive for Rational Mechanics and Analysis","oa_version":"Published Version","file_date_updated":"2025-03-17T10:07:45Z","intvolume":" 249","file":[{"success":1,"date_updated":"2025-03-17T10:07:45Z","file_id":"19412","file_name":"2025_ArchiveRatMech_Roos.pdf","creator":"dernst","relation":"main_file","checksum":"66803fb63a57987eb4f13ee2949bea77","file_size":1224282,"date_created":"2025-03-17T10:07:45Z","content_type":"application/pdf","access_level":"open_access"}],"isi":1,"date_updated":"2025-09-30T11:01:08Z","oa":1},{"acknowledgement":"We thank the anonymous referee for providing constructive comments that improved the paper. This paper includes data collected by the Kepler mission and obtained from the MAST data archive at the Space Telescope Science Institute (STScI). Funding for the Kepler mission is provided by the NASA Science Mission Directorate. STScI is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-26555. M.H.P. acknowledges support from NASA grants 80NSSC24K0637 and 80NSSC18K1582. M.H.P., J.T., and P.M.F. acknowledge that part of this work was performed at the Aspen Center for Physics, which is supported by National Science Foundation grant PHY-1607611. M.H.P. acknowledges support from the Fundación Occident and the Instituto de Astrofísica de Canarias under the Visiting Researcher Programme 2022-2025 agreed between both institutions. A.S. acknowledges support by the Spanish Ministry of Science, Innovation and Universities through the grant PID2023-149918NB-I00 and the program Unidad de Excelencia Marìa de Maeztu CEX2020-001058-M, and by Generalitat de Catalunya through grant 2021-SGR-1526. S.B. acknowledges NSF grant AST-2205026. P.G.B. acknowledges support by the Spanish Ministry of Science and Innovation with the Ramón y Cajal fellowship Nos. RYC-2021-033137-I and MRR4032204. D.S. is supported by the Australian Research Council (DP190100666). P.G.B., D.G.R., and R.A.G. acknowledge support from the Spanish Ministry of Science and Innovation from grant No. PID2023-146453NB-100 (PLAtoSOnG). M.V. acknowledges support from NASA grant 80NSSC18K1582 and funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program (grant agreement No. 101019653). T.C.B. acknowledges partial support for this work from grant PHY 14-30152; Physics Frontier Center/JINA Center for the Evolution of the Elements (JINA-CEE), and OISE-1927130: The International Research Network for Nuclear Astrophysics (IReNA), awarded by the US National Science Foundation. The research leading to the presented results has received funding from the ERC Consolidator Grant DipolarSound (grant agreement No. 101000296). P.F. and T.S. acknowledges support from the National Science Foundation Astronomy and Astrophysics grants AST-1715662 and AST-2206541. S.M. acknowledges support by the Spanish Ministry of Science and Innovation with the Ramon y Cajal fellowship Nos. RYC-2015-17697, PID2019-107061GB-C66, and PID2023-149439NB-C41, and through AEI under the Severo Ochoa Centres of Excellence Programme 2020–2023 (CEX2019-000920-S). S.M. and D.G.R. acknowledge support from the Spanish Ministry of Science and Innovation (MICINN) from grant No. PID2019-107187GB-I00. D.G.R. acknowledges support from the Spanish Ministry of Science and Innovation (MICINN) with the Juan de la Cierva program under contract JDC2022-049054-I. L.B. gratefully acknowledges support from the European Research Council (ERC) under the Horizon Europe program (Calcifer; Starting grant agreement No. 101165631). A.R.G.S. acknowledges the support from the FCT through national funds and FEDER through COMPETE2020 (UIDB/04434/2020, UIDP/04434/2020, and 2022.03993.PTDC) and the support from the FCT through work contract No. 2020.02480.CEECIND/CP1631/CT0001.\r\n\r\nFunding for the Sloan Digital Sky Survey IV has been provided by the Alfred P. Sloan Foundation, the U.S. Department of Energy Office of Science, and the Participating Institutions. SDSS acknowledges support and resources from the Center for High-Performance Computing at the University of Utah. The SDSS website is www.sdss4.org.\r\n\r\nSDSS is managed by the Astrophysical Research Consortium for the Participating Institutions of the SDSS Collaboration including the Brazilian Participation Group, the Carnegie Institution for Science, Carnegie Mellon University, Center for Astrophysics—Harvard & Smithsonian (CfA), the Chilean Participation Group, the French Participation Group, Instituto de Astrofísica de Canarias, The Johns Hopkins University, Kavli Institute for the Physics and Mathematics of the Universe (IPMU)/University of Tokyo, the Korean Participation Group, Lawrence Berkeley National Laboratory, Leibniz Institut für Astrophysik Potsdam (AIP), Max-Planck-Institut für Astronomie (MPIA Heidelberg), Max-Planck-Institut für Astrophysik (MPA Garching), Max-Planck-Institut für Extraterrestrische Physik (MPE), National Astronomical Observatories of China, New Mexico State University, New York University, University of Notre Dame, Observatório Nacional/MCTI, The Ohio State University, Pennsylvania State University, Shanghai Astronomical Observatory, United Kingdom Participation Group, Universidad Nacional Autónoma de México, University of Arizona, University of Colorado Boulder, University of Oxford, University of Portsmouth, University of Utah, University of Virginia, University of Washington, University of Wisconsin, Vanderbilt University, and Yale University.","abstract":[{"text":"In the third APOKASC catalog, we present data for the complete sample of 15,808 evolved stars with APOGEE spectroscopic parameters and Kepler asteroseismology. We used 10 independent asteroseismic analysis techniques and anchor our system on fundamental radii derived from Gaia L and spectroscopic Teff. We provide evolutionary state, asteroseismic surface gravity, mass, radius, age, and the data used to derive them for 12,418 stars. This includes 10,036 exceptionally precise measurements, with median fractional uncertainties in \r\nvmax, Δν, mass, radius, and age of 0.6%, 0.6%, 3.8%, 1.8%, and 11.1%, respectively. We provide more limited data for 1624 additional stars that either have lower-quality data or are outside of our primary calibration domain. Using lower red giant branch (RGB) stars, we find a median age for the chemical thick disk of 9.14 ± 0.05(ran) ± 0.9(sys) Gyr with an age dispersion of 1.1 Gyr, consistent with our error model. We calibrate our red clump (RC) mass loss to derive an age consistent with the lower RGB and provide asymptotic GB and RGB ages for luminous stars. We also find a sharp upper-age boundary in the chemical thin disk. We find that scaling relations are precise and accurate on the lower RGB and RC, but they become more model dependent for more luminous giants and break down at the tip of the RGB. We recommend the use of multiple methods, calibration to a fundamental scale, and the use of stellar models to interpret frequency spacings.","lang":"eng"}],"title":"APOKASC-3: The third joint spectroscopic and asteroseismic catalog for evolved stars in the Kepler fields","quality_controlled":"1","issue":"2","status":"public","publisher":"IOP Publishing","doi":"10.3847/1538-4365/ad9fef","OA_type":"gold","citation":{"ama":"Pinsonneault MH, Zinn JC, Tayar J, et al. APOKASC-3: The third joint spectroscopic and asteroseismic catalog for evolved stars in the Kepler fields. Astrophysical Journal, Supplement Series. 2025;276(2). doi:10.3847/1538-4365/ad9fef","mla":"Pinsonneault, Marc H., et al. “APOKASC-3: The Third Joint Spectroscopic and Asteroseismic Catalog for Evolved Stars in the Kepler Fields.” Astrophysical Journal, Supplement Series, vol. 276, no. 2, 69, IOP Publishing, 2025, doi:10.3847/1538-4365/ad9fef.","ista":"Pinsonneault MH, Zinn JC, Tayar J, Serenelli A, García RA, Mathur S, Vrard M, Elsworth YP, Mosser B, Stello D, Bell KJ, Bugnet LA, Corsaro E, Gaulme P, Hekker S, Hon M, Huber D, Kallinger T, Cao K, Johnson JA, Liagre B, Patton RA, Santos ÂRG, Basu S, Beck PG, Beers TC, Chaplin WJ, Cunha K, Frinchaboy PM, Girardi L, Godoy-Rivera D, Holtzman JA, Jönsson H, Mészáros S, Reyes C, Rix HW, Shetrone M, Smith VV, Spoo T, Stassun KG, Wang J. 2025. APOKASC-3: The third joint spectroscopic and asteroseismic catalog for evolved stars in the Kepler fields. Astrophysical Journal, Supplement Series. 276(2), 69.","short":"M.H. Pinsonneault, J.C. Zinn, J. Tayar, A. Serenelli, R.A. García, S. Mathur, M. Vrard, Y.P. Elsworth, B. Mosser, D. Stello, K.J. Bell, L.A. Bugnet, E. Corsaro, P. Gaulme, S. Hekker, M. Hon, D. Huber, T. Kallinger, K. Cao, J.A. Johnson, B. Liagre, R.A. Patton, Â.R.G. Santos, S. Basu, P.G. Beck, T.C. Beers, W.J. Chaplin, K. Cunha, P.M. Frinchaboy, L. Girardi, D. Godoy-Rivera, J.A. Holtzman, H. Jönsson, S. Mészáros, C. Reyes, H.W. Rix, M. Shetrone, V.V. Smith, T. Spoo, K.G. Stassun, J. Wang, Astrophysical Journal, Supplement Series 276 (2025).","ieee":"M. H. Pinsonneault et al., “APOKASC-3: The third joint spectroscopic and asteroseismic catalog for evolved stars in the Kepler fields,” Astrophysical Journal, Supplement Series, vol. 276, no. 2. IOP Publishing, 2025.","chicago":"Pinsonneault, Marc H., Joel C. Zinn, Jamie Tayar, Aldo Serenelli, Rafael A. García, Savita Mathur, Mathieu Vrard, et al. “APOKASC-3: The Third Joint Spectroscopic and Asteroseismic Catalog for Evolved Stars in the Kepler Fields.” Astrophysical Journal, Supplement Series. IOP Publishing, 2025. https://doi.org/10.3847/1538-4365/ad9fef.","apa":"Pinsonneault, M. H., Zinn, J. C., Tayar, J., Serenelli, A., García, R. A., Mathur, S., … Wang, J. (2025). APOKASC-3: The third joint spectroscopic and asteroseismic catalog for evolved stars in the Kepler fields. Astrophysical Journal, Supplement Series. IOP Publishing. https://doi.org/10.3847/1538-4365/ad9fef"},"OA_place":"publisher","publication_status":"published","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"year":"2025","volume":276,"file":[{"creator":"dernst","file_name":"2025_AstrophysicalJourSuppl_Pinsonneault.pdf","date_updated":"2025-03-17T10:40:41Z","file_id":"19414","success":1,"access_level":"open_access","content_type":"application/pdf","date_created":"2025-03-17T10:40:41Z","file_size":4993506,"checksum":"a01a6645c6cb0b5cc75490f3339a2244","relation":"main_file"}],"isi":1,"date_updated":"2025-09-30T11:03:01Z","oa":1,"publication":"Astrophysical Journal, Supplement Series","oa_version":"Published Version","file_date_updated":"2025-03-17T10:40:41Z","intvolume":" 276","_id":"19405","DOAJ_listed":"1","month":"02","date_created":"2025-03-16T23:01:24Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","department":[{"_id":"LiBu"}],"article_type":"original","type":"journal_article","article_processing_charge":"Yes","day":"01","publication_identifier":{"issn":["0067-0049"]},"scopus_import":"1","author":[{"full_name":"Pinsonneault, Marc H.","first_name":"Marc H.","last_name":"Pinsonneault"},{"full_name":"Zinn, Joel C.","first_name":"Joel C.","last_name":"Zinn"},{"last_name":"Tayar","full_name":"Tayar, Jamie","first_name":"Jamie"},{"full_name":"Serenelli, Aldo","first_name":"Aldo","last_name":"Serenelli"},{"last_name":"García","first_name":"Rafael A.","full_name":"García, Rafael A."},{"last_name":"Mathur","full_name":"Mathur, Savita","first_name":"Savita"},{"full_name":"Vrard, Mathieu","first_name":"Mathieu","last_name":"Vrard"},{"last_name":"Elsworth","first_name":"Yvonne P.","full_name":"Elsworth, Yvonne P."},{"full_name":"Mosser, Benoit","first_name":"Benoit","last_name":"Mosser"},{"first_name":"Dennis","full_name":"Stello, Dennis","last_name":"Stello"},{"first_name":"Keaton J.","full_name":"Bell, Keaton J.","last_name":"Bell"},{"full_name":"Bugnet, Lisa Annabelle","id":"d9edb345-f866-11ec-9b37-d119b5234501","first_name":"Lisa Annabelle","last_name":"Bugnet","orcid":"0000-0003-0142-4000"},{"last_name":"Corsaro","full_name":"Corsaro, Enrico","first_name":"Enrico"},{"last_name":"Gaulme","full_name":"Gaulme, Patrick","first_name":"Patrick"},{"last_name":"Hekker","first_name":"Saskia","full_name":"Hekker, Saskia"},{"full_name":"Hon, Marc","first_name":"Marc","last_name":"Hon"},{"last_name":"Huber","first_name":"Daniel","full_name":"Huber, Daniel"},{"last_name":"Kallinger","full_name":"Kallinger, Thomas","first_name":"Thomas"},{"last_name":"Cao","full_name":"Cao, Kaili","first_name":"Kaili"},{"full_name":"Johnson, Jennifer A.","first_name":"Jennifer A.","last_name":"Johnson"},{"full_name":"Liagre, Bastien","first_name":"Bastien","last_name":"Liagre"},{"last_name":"Patton","full_name":"Patton, Rachel A.","first_name":"Rachel A."},{"first_name":"Ângela R.G.","full_name":"Santos, Ângela R.G.","last_name":"Santos"},{"last_name":"Basu","first_name":"Sarbani","full_name":"Basu, Sarbani"},{"first_name":"Paul G.","full_name":"Beck, Paul G.","last_name":"Beck"},{"full_name":"Beers, Timothy C.","first_name":"Timothy C.","last_name":"Beers"},{"first_name":"William J.","full_name":"Chaplin, William J.","last_name":"Chaplin"},{"first_name":"Katia","full_name":"Cunha, Katia","last_name":"Cunha"},{"first_name":"Peter M.","full_name":"Frinchaboy, Peter M.","last_name":"Frinchaboy"},{"last_name":"Girardi","full_name":"Girardi, Léo","first_name":"Léo"},{"last_name":"Godoy-Rivera","first_name":"Diego","full_name":"Godoy-Rivera, Diego"},{"first_name":"Jon A.","full_name":"Holtzman, Jon A.","last_name":"Holtzman"},{"last_name":"Jönsson","full_name":"Jönsson, Henrik","first_name":"Henrik"},{"last_name":"Mészáros","full_name":"Mészáros, Szabolcs","first_name":"Szabolcs"},{"first_name":"Claudia","full_name":"Reyes, Claudia","last_name":"Reyes"},{"full_name":"Rix, Hans Walter","first_name":"Hans Walter","last_name":"Rix"},{"first_name":"Matthew","full_name":"Shetrone, Matthew","last_name":"Shetrone"},{"full_name":"Smith, Verne V.","first_name":"Verne V.","last_name":"Smith"},{"first_name":"Taylor","full_name":"Spoo, Taylor","last_name":"Spoo"},{"first_name":"Keivan G.","full_name":"Stassun, Keivan G.","last_name":"Stassun"},{"full_name":"Wang, Ji","first_name":"Ji","last_name":"Wang"}],"article_number":"69","language":[{"iso":"eng"}],"date_published":"2025-02-01T00:00:00Z","external_id":{"arxiv":["2410.00102"],"isi":["001414132600001"]},"arxiv":1,"has_accepted_license":"1","ddc":["520"],"fulldoi":"https://doi.org/10.3847/1538-4365/ad9fef"},{"type":"journal_article","article_processing_charge":"No","day":"01","publication_identifier":{"eissn":["1469-8137"],"issn":["0028-646X"]},"scopus_import":"1","author":[{"first_name":"Xin","full_name":"Song, Xin","last_name":"Song"},{"first_name":"Miao","full_name":"Zhang, Miao","last_name":"Zhang"},{"last_name":"Wang","full_name":"Wang, Ting Ting","first_name":"Ting Ting"},{"first_name":"Yao Yuan","full_name":"Duan, Yao Yuan","last_name":"Duan"},{"first_name":"Jie","full_name":"Ren, Jie","last_name":"Ren"},{"full_name":"Gao, Hu","first_name":"Hu","last_name":"Gao"},{"full_name":"Fan, Yan Jie","first_name":"Yan Jie","last_name":"Fan"},{"last_name":"Xia","first_name":"Qiang Ming","full_name":"Xia, Qiang Ming"},{"last_name":"Cao","first_name":"Hui Xiang","full_name":"Cao, Hui Xiang"},{"full_name":"Xie, Kai Dong","first_name":"Kai Dong","last_name":"Xie"},{"full_name":"Wu, Xiao Meng","first_name":"Xiao Meng","last_name":"Wu"},{"full_name":"Zhang, Fei","first_name":"Fei","last_name":"Zhang"},{"first_name":"Si Qi","full_name":"Zhang, Si Qi","last_name":"Zhang"},{"last_name":"Huang","full_name":"Huang, Ying","id":"11b5bbff-8b61-11ed-b69e-d8ddd6bce951","first_name":"Ying"},{"first_name":"Adnane","full_name":"Boualem, Adnane","last_name":"Boualem"},{"full_name":"Bendahmane, Abdelhafid","first_name":"Abdelhafid","last_name":"Bendahmane"},{"first_name":"Feng Quan","full_name":"Tan, Feng Quan","last_name":"Tan"},{"last_name":"Guo","full_name":"Guo, Wen Wu","first_name":"Wen Wu"}],"page":"176-191","language":[{"iso":"eng"}],"date_published":"2025-04-01T00:00:00Z","external_id":{"pmid":["39969116"],"isi":["001424915600001"]},"pmid":1,"fulldoi":"https://doi.org/10.1111/nph.20428","acknowledgement":"We thank Prof. Qi Xie from the Institute of Genetics and Development, Chinese Academy of Sciences, for providing the YAO promoter-driven CRISPR/Cas9 vector, our colleague Dr Robert M. Larkin from Huazhong Agricultural University, and Dr Olivier Martin from IPS2 (INRAE, France) for critical reading of the manuscript. This research was financially supported by grants from the National Key Research & Development Program of China (2024YFD1200501), the National Natural Science Foundation of China (32172525 and 32202432), the Foundation of Hubei Hongshan laboratory (2021hszd009), the China Agricultural Research System (CARS-26) and the Department of Science and Technology of Hubei Province (2022BBA0019). A. Bendahmane is funded by the ANR BioAdapt (ANR-21-LCV3-0003), LabEx Saclay Plant Sciences (SPS) (ANR-10-LABX-40-SPS), and the NectarGland ERC Project (101095736).","title":"Polyploidization leads to salt stress resilience via ethylene signaling in citrus plants","abstract":[{"text":"Polyploidization is a common occurrence in the evolutionary history of flowering plants, significantly contributing to their adaptability and diversity. However, the molecular mechanisms behind these adaptive advantages are not well understood.\r\nThrough comprehensive phenotyping of diploid and tetraploid clones from Citrus and Poncirus genera, we discovered that genome doubling significantly enhances salt stress resilience. Epigenetic and transcriptomic analyses revealed that increased ethylene production in the roots of tetraploid plants was associated with hypomethylation and enhanced chromatin accessibility of the ACO1 gene. This increased ethylene production activates the transcription of reactive oxygen species scavenging genes and stress-related hormone biosynthesis genes. Consequently, tetraploid plants exhibited superior root functionality under salt stress, maintaining improved cytosolic K+/Na+ homeostasis.\r\nTo genetically validate the link between salt stress resilience and ACO1 expression, we generated overexpression and knockout lines, confirming the central role of ACO1 expression regulation following genome doubling in salt stress resilience.\r\nOur work elucidates the molecular mechanisms underlying the role of genome doubling in stress resilience. We also highlight the importance of chromatin dynamics in fine-tuning ethylene gene expression and activating salt stress resilience pathways, offering valuable insights into plant adaptation and crop genome evolution.","lang":"eng"}],"quality_controlled":"1","issue":"1","status":"public","publisher":"Wiley","doi":"10.1111/nph.20428","OA_type":"closed access","publication_status":"published","citation":{"mla":"Song, Xin, et al. “Polyploidization Leads to Salt Stress Resilience via Ethylene Signaling in Citrus Plants.” New Phytologist, vol. 246, no. 1, Wiley, 2025, pp. 176–91, doi:10.1111/nph.20428.","ama":"Song X, Zhang M, Wang TT, et al. Polyploidization leads to salt stress resilience via ethylene signaling in citrus plants. New Phytologist. 2025;246(1):176-191. doi:10.1111/nph.20428","ista":"Song X, Zhang M, Wang TT, Duan YY, Ren J, Gao H, Fan YJ, Xia QM, Cao HX, Xie KD, Wu XM, Zhang F, Zhang SQ, Huang Y, Boualem A, Bendahmane A, Tan FQ, Guo WW. 2025. Polyploidization leads to salt stress resilience via ethylene signaling in citrus plants. New Phytologist. 246(1), 176–191.","ieee":"X. Song et al., “Polyploidization leads to salt stress resilience via ethylene signaling in citrus plants,” New Phytologist, vol. 246, no. 1. Wiley, pp. 176–191, 2025.","short":"X. Song, M. Zhang, T.T. Wang, Y.Y. Duan, J. Ren, H. Gao, Y.J. Fan, Q.M. Xia, H.X. Cao, K.D. Xie, X.M. Wu, F. Zhang, S.Q. Zhang, Y. Huang, A. Boualem, A. Bendahmane, F.Q. Tan, W.W. Guo, New Phytologist 246 (2025) 176–191.","apa":"Song, X., Zhang, M., Wang, T. T., Duan, Y. Y., Ren, J., Gao, H., … Guo, W. W. (2025). Polyploidization leads to salt stress resilience via ethylene signaling in citrus plants. New Phytologist. Wiley. https://doi.org/10.1111/nph.20428","chicago":"Song, Xin, Miao Zhang, Ting Ting Wang, Yao Yuan Duan, Jie Ren, Hu Gao, Yan Jie Fan, et al. “Polyploidization Leads to Salt Stress Resilience via Ethylene Signaling in Citrus Plants.” New Phytologist. Wiley, 2025. https://doi.org/10.1111/nph.20428."},"year":"2025","volume":246,"isi":1,"date_updated":"2025-09-30T11:00:06Z","oa_version":"None","publication":"New Phytologist","intvolume":" 246","_id":"19406","month":"04","date_created":"2025-03-16T23:01:25Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","department":[{"_id":"XiFe"}],"article_type":"original"},{"abstract":[{"text":"This .zip file contains the data to reproduce the figures and supplementary figures of \"Exchange anisotropies in microwave-driven singlet-triplet qubits\" by Jaime Saez-Mollejo et al.\r\n","lang":"eng"}],"title":"Exchange anisotropies in microwave-driven singlet-triplet qubits","acknowledgement":"We thank A. Crippa for helpful discussions. This research was supported by the Scientific Service Units of ISTA through resources provided by the MIBA Machine Shop and the Nanofabrication facility. This research and related results were made possible with the support of the NOMIS Foundation, the HORIZON-RIA 101069515 project and the FWF Projects \r\nwith DOI:10.55776/F86 and DOI:10.55776/I5060. M.R.-R. acknowledges support from the Netherlands Organization of\r\n scientific Research (NWO) under Veni grant VI.Veni.212.223. The Research of S.B. and M.R.-R. was sponsored in part by the Army Research Office and was accomplished under Award Number: W911NF-23-1-0110.","project":[{"grant_number":"101069515","_id":"34c0acea-11ca-11ed-8bc3-8775e10fd452","name":"Integrated Germanium Quantum Technology"},{"name":"High impedance circuit quantum electrodynamics with hole spins","_id":"c0977eea-5a5b-11eb-8a69-a862db0cf4d1","grant_number":"I05060"},{"grant_number":"F8606","_id":"34a66131-11ca-11ed-8bc3-a31681c6b03e","name":"Center for Correlated Quantum Materials and Solid State Quantum Systems: Conventional and unconventional topological superconductors"}],"publisher":"Institute of Science and Technology Austria","status":"public","OA_type":"gold","doi":"10.15479/AT:ISTA:19409","year":"2025","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"OA_place":"publisher","citation":{"apa":"Saez Mollejo, J. (2025). Exchange anisotropies in microwave-driven singlet-triplet qubits. Institute of Science and Technology Austria. https://doi.org/10.15479/AT:ISTA:19409","chicago":"Saez Mollejo, Jaime. “Exchange Anisotropies in Microwave-Driven Singlet-Triplet Qubits.” Institute of Science and Technology Austria, 2025. https://doi.org/10.15479/AT:ISTA:19409.","ieee":"J. Saez Mollejo, “Exchange anisotropies in microwave-driven singlet-triplet qubits.” Institute of Science and Technology Austria, 2025.","short":"J. Saez Mollejo, (2025).","ista":"Saez Mollejo J. 2025. Exchange anisotropies in microwave-driven singlet-triplet qubits, Institute of Science and Technology Austria, 10.15479/AT:ISTA:19409.","mla":"Saez Mollejo, Jaime. Exchange Anisotropies in Microwave-Driven Singlet-Triplet Qubits. Institute of Science and Technology Austria, 2025, doi:10.15479/AT:ISTA:19409.","ama":"Saez Mollejo J. Exchange anisotropies in microwave-driven singlet-triplet qubits. 2025. doi:10.15479/AT:ISTA:19409"},"oa":1,"date_updated":"2026-05-20T06:42:16Z","file":[{"access_level":"open_access","date_created":"2025-03-17T08:48:09Z","content_type":"application/x-zip-compressed","checksum":"1f21c8ea2196776aae51cc3a5d00e00b","file_size":21971911,"relation":"main_file","creator":"jsaezmol","file_name":"AllDataPublished.zip","success":1,"file_id":"19410","date_updated":"2025-03-17T08:48:09Z"}],"related_material":{"record":[{"relation":"used_in_publication","status":"public","id":"19424"}]},"file_date_updated":"2025-03-17T08:48:09Z","oa_version":"Published Version","month":"03","_id":"19409","department":[{"_id":"GradSch"},{"_id":"GeKa"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2025-03-17T08:57:09Z","article_processing_charge":"No","acknowledged_ssus":[{"_id":"NanoFab"},{"_id":"M-Shop"}],"contributor":[{"id":"4C473F58-F248-11E8-B48F-1D18A9856A87","first_name":"Daniel","last_name":"Jirovec","orcid":"0000-0002-7197-4801"},{"first_name":"Yona A","id":"fe39122d-06bb-11ec-a33b-9e22b40e40a5","last_name":"Schell"},{"id":"3F5D8856-F248-11E8-B48F-1D18A9856A87","first_name":"Josip","last_name":"Kukucka"},{"last_name":"Calcaterra","first_name":"Stefano"},{"first_name":"Daniel ","last_name":"Chrastina"},{"first_name":"Giovanni ","last_name":"Isella"},{"last_name":"Rimbach-Russ","first_name":"Maximilian"},{"first_name":"Stefano","last_name":"Bosco"},{"first_name":"Georgios","id":"38DB5788-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8342-202X","last_name":"Katsaros"}],"type":"research_data","day":"17","author":[{"full_name":"Saez Mollejo, Jaime","first_name":"Jaime","id":"e0390f72-f6e0-11ea-865d-862393336714","last_name":"Saez Mollejo"}],"corr_author":"1","date_published":"2025-03-17T00:00:00Z","fulldoi":"https://doi.org/10.15479/AT:ISTA:19409","ddc":["530"],"has_accepted_license":"1"},{"year":"2025","tmp":{"image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"},"volume":17,"OA_place":"publisher","citation":{"chicago":"Casallas Garcia, Alejandro, A.M. Tompkins, Caroline J Muller, and G. Thompson. “Sensitivity of Self-Aggregation and the Key Role of the Free Convection Distance.” Journal of Advances in Modeling Earth Systems. Wiley, 2025. https://doi.org/10.1029/2024MS004791.","apa":"Casallas Garcia, A., Tompkins, A. M., Muller, C. J., & Thompson, G. (2025). Sensitivity of self-aggregation and the key role of the free convection distance. Journal of Advances in Modeling Earth Systems. Wiley. https://doi.org/10.1029/2024MS004791","short":"A. Casallas Garcia, A.M. Tompkins, C.J. Muller, G. Thompson, Journal of Advances in Modeling Earth Systems 17 (2025).","ieee":"A. Casallas Garcia, A. M. Tompkins, C. J. Muller, and G. Thompson, “Sensitivity of self-aggregation and the key role of the free convection distance,” Journal of Advances in Modeling Earth Systems, vol. 17, no. 3. Wiley, 2025.","ista":"Casallas Garcia A, Tompkins AM, Muller CJ, Thompson G. 2025. Sensitivity of self-aggregation and the key role of the free convection distance. Journal of Advances in Modeling Earth Systems. 17(3), e2024MS004791.","ama":"Casallas Garcia A, Tompkins AM, Muller CJ, Thompson G. Sensitivity of self-aggregation and the key role of the free convection distance. Journal of Advances in Modeling Earth Systems. 2025;17(3). doi:10.1029/2024MS004791","mla":"Casallas Garcia, Alejandro, et al. “Sensitivity of Self-Aggregation and the Key Role of the Free Convection Distance.” Journal of Advances in Modeling Earth Systems, vol. 17, no. 3, e2024MS004791, Wiley, 2025, doi:10.1029/2024MS004791."},"publication_status":"published","OA_type":"gold","doi":"10.1029/2024MS004791","issue":"3","status":"public","project":[{"name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"},{"name":"Organization of CLoUdS, and implications of Tropical cyclones and for the Energetics of the tropics, in current and waRming climate","grant_number":"805041","_id":"629205d8-2b32-11ec-9570-e1356ff73576","call_identifier":"H2020"}],"publisher":"Wiley","quality_controlled":"1","abstract":[{"lang":"eng","text":"Recently, Biagioli and Tompkins (2023, https://doi.org/10.1029/2022ms003231) used a simple stochastic model to derive a dimensionless parameter to predict convective self aggregation (SA) development, which was based on the derivation of the maximum free convective distance ($d_{clr}$) expected in the pre-aggregated, random state. Our goal is to test and further investigate this hypothesis, namely that $d_{clr}$ can predict SA occurrence, using an ensemble of twenty-four distinct combinations of horizontal mixing, planetary boundary layer (PBL), and microphysical parameterizations. We conclude that the key impact of parameterization schemes on SA is through their control of the number of convective cores and their relative spacing, $d_{clr}$, which itself is impacted by cold-pool (CP) properties and mean updraft core size. SA is more likely when the convective core count is small, while CPs modify convective spacing via suppression in their interiors and triggering by gust-front convergence and collisions. Each parameterization scheme emphasizes a different mechanism. Subgrid-scale horizontal turbulent mixing mainly affects SA through the determination of convective core size and thus spacing. The sensitivity to the microphysics is mainly through rain evaporation and the subsequent impact on CPs, while perturbations to the ice cloud microphysics have a limited effect. Non-local PBL mixing schemes promote SA primarily by increasing convective inhibition through inversion entrainment and altering low cloud amounts, leading to fewer convective cores and larger $d_{clr}$. "}],"title":"Sensitivity of self-aggregation and the key role of the free convection distance","acknowledgement":"This article is based on chapter 3 of AC Ph.D. thesis. The authors thank Graziano Giuliani for his coding assistance. We also thank Daniel Hernández-Deckers, Paolina Cerlini, and especially to Giovanni Biagioli for discussions and feedback. We also thank two reviewers for their insightful comments. AC was supported by a fellowship awarded by ICTP and by the European Union Horizon 2020 Marie Skłodowska-Curie grant agreement No. 101034413. CM acknowledges funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program (Project CLUSTER, Grant Agreement No. 805041).","department":[{"_id":"CaMu"}],"article_type":"original","date_created":"2025-03-19T07:58:38Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","month":"03","_id":"19416","ec_funded":1,"file_date_updated":"2025-03-19T07:58:21Z","intvolume":" 17","oa_version":"Published Version","publication":"Journal of Advances in Modeling Earth Systems","isi":1,"date_updated":"2025-09-30T11:04:38Z","file":[{"content_type":"application/pdf","date_created":"2025-03-19T07:58:21Z","access_level":"open_access","relation":"main_file","checksum":"bc32677e63f8abb07b330f4a08da796d","file_size":18285343,"creator":"acasalla","file_name":"Casallas_et_al_2025_dclr.pdf","date_updated":"2025-03-19T07:58:21Z","file_id":"19417"}],"oa":1,"corr_author":"1","article_number":"e2024MS004791","author":[{"last_name":"Casallas Garcia","orcid":"0000-0002-1988-5035","full_name":"Casallas Garcia, Alejandro","first_name":"Alejandro","id":"92081129-2d75-11ef-a48d-b04dd7a2385a"},{"last_name":"Tompkins","full_name":"Tompkins, A.M.","first_name":"A.M."},{"first_name":"Caroline J","id":"f978ccb0-3f7f-11eb-b193-b0e2bd13182b","full_name":"Muller, Caroline J","last_name":"Muller","orcid":"0000-0001-5836-5350"},{"full_name":"Thompson, G.","first_name":"G.","last_name":"Thompson"}],"publication_identifier":{"eissn":["1942-2466"]},"scopus_import":"1","day":"18","article_processing_charge":"Yes","type":"journal_article","ddc":["550"],"fulldoi":"https://doi.org/10.1029/2024MS004791","has_accepted_license":"1","external_id":{"isi":["001447023900001"]},"date_published":"2025-03-18T00:00:00Z","language":[{"iso":"eng"}]},{"article_type":"original","department":[{"_id":"MaKw"}],"date_created":"2025-03-19T09:03:37Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","month":"03","ec_funded":1,"_id":"19418","intvolume":" 111","file_date_updated":"2025-03-20T09:46:20Z","oa_version":"Published Version","publication":"Journal of the London Mathematical Society","oa":1,"date_updated":"2025-09-30T11:05:07Z","file":[{"file_id":"19427","date_updated":"2025-03-20T09:46:20Z","success":1,"file_name":"2025_JournLondonMath_Draganic.pdf","creator":"dernst","file_size":625974,"checksum":"d8e0a03286a44c4f672709e3c829206e","relation":"main_file","access_level":"open_access","content_type":"application/pdf","date_created":"2025-03-20T09:46:20Z"}],"isi":1,"volume":111,"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"year":"2025","citation":{"ista":"Draganić N, Petrova KH. 2025. Size‐Ramsey numbers of graphs with maximum degree three. Journal of the London Mathematical Society. 111(3), e70116.","mla":"Draganić, Nemanja, and Kalina H. Petrova. “Size‐Ramsey Numbers of Graphs with Maximum Degree Three.” Journal of the London Mathematical Society, vol. 111, no. 3, e70116, Wiley, 2025, doi:10.1112/jlms.70116.","ama":"Draganić N, Petrova KH. Size‐Ramsey numbers of graphs with maximum degree three. Journal of the London Mathematical Society. 2025;111(3). doi:10.1112/jlms.70116","apa":"Draganić, N., & Petrova, K. H. (2025). Size‐Ramsey numbers of graphs with maximum degree three. Journal of the London Mathematical Society. Wiley. https://doi.org/10.1112/jlms.70116","chicago":"Draganić, Nemanja, and Kalina H Petrova. “Size‐Ramsey Numbers of Graphs with Maximum Degree Three.” Journal of the London Mathematical Society. Wiley, 2025. https://doi.org/10.1112/jlms.70116.","ieee":"N. Draganić and K. H. Petrova, “Size‐Ramsey numbers of graphs with maximum degree three,” Journal of the London Mathematical Society, vol. 111, no. 3. Wiley, 2025.","short":"N. Draganić, K.H. Petrova, Journal of the London Mathematical Society 111 (2025)."},"publication_status":"published","OA_place":"publisher","OA_type":"hybrid","doi":"10.1112/jlms.70116","project":[{"name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"publisher":"Wiley","status":"public","issue":"3","quality_controlled":"1","abstract":[{"lang":"eng","text":"The size-Ramsey number r^(H) of a graph H is the smallest number of edges a (host) graph G can have, such that for any red/blue colouring of G, there is a monochromatic copy of H in G. Recently, Conlon, Nenadov and Trujić showed that if H is a graph on n vertices and maximum degree three, then r^(H)=O(n8/5), improving upon the upper bound of n5/3+o(1) by Kohayakawa, Rödl, Schacht and Szemerédi. In this paper we show that r^(H)≤n3/2+o(1). While the previously used host graphs were vanilla binomial random graphs, we prove our result using a novel host graph construction. Our bound hits a natural barrier of the existing methods."}],"title":"Size‐Ramsey numbers of graphs with maximum degree three","acknowledgement":"We would like to thank Rajko Nenadov and Miloš Trujić for helpful comments and discussions, as well as the anonymous referees for their very useful feedback, which improved the paper considerably. This research was supported by SNSF Project 217926. Part of this research was conducted while Nemanja Draganić was at ETH Zürich, Switzerland, and partially supported by SNSF Grant 200021_196965. This project has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement Number: 101034413. Part of this research was conducted while Kalina Petrova was at the Department of Computer Science, ETH Zürich, Switzerland, supported by SNSF Grant CRSII5 173721.","fulldoi":"https://doi.org/10.1112/jlms.70116","ddc":["510"],"has_accepted_license":"1","arxiv":1,"external_id":{"arxiv":["2207.05048"],"isi":["001450645400019"]},"date_published":"2025-03-01T00:00:00Z","language":[{"iso":"eng"}],"article_number":"e70116","author":[{"last_name":"Draganić","first_name":"Nemanja","full_name":"Draganić, Nemanja"},{"last_name":"Petrova","id":"554ff4e4-f325-11ee-b0c4-a10dbd523381","first_name":"Kalina H","full_name":"Petrova, Kalina H"}],"scopus_import":"1","publication_identifier":{"eissn":["1469-7750"],"issn":["0024-6107"]},"day":"01","article_processing_charge":"No","type":"journal_article"},{"year":"2025","publication_status":"published","citation":{"ieee":"H. Tang, L. Chen, and J. Friml, “Auxin fluctuation and PIN polarization in moss leaf cell reprogramming.,” Plant and Cell Physiology. Oxford University Press, 2025.","short":"H. Tang, L. Chen, J. Friml, Plant and Cell Physiology (2025).","apa":"Tang, H., Chen, L., & Friml, J. (2025). Auxin fluctuation and PIN polarization in moss leaf cell reprogramming. Plant and Cell Physiology. Oxford University Press. https://doi.org/10.1093/pcp/pcaf008","chicago":"Tang, Han, L Chen, and Jiří Friml. “Auxin Fluctuation and PIN Polarization in Moss Leaf Cell Reprogramming.” Plant and Cell Physiology. Oxford University Press, 2025. https://doi.org/10.1093/pcp/pcaf008.","mla":"Tang, Han, et al. “Auxin Fluctuation and PIN Polarization in Moss Leaf Cell Reprogramming.” Plant and Cell Physiology, pcaf008, Oxford University Press, 2025, doi:10.1093/pcp/pcaf008.","ama":"Tang H, Chen L, Friml J. Auxin fluctuation and PIN polarization in moss leaf cell reprogramming. Plant and Cell Physiology. 2025. doi:10.1093/pcp/pcaf008","ista":"Tang H, Chen L, Friml J. 2025. Auxin fluctuation and PIN polarization in moss leaf cell reprogramming. Plant and Cell Physiology., pcaf008."},"OA_type":"closed access","doi":"10.1093/pcp/pcaf008","status":"public","project":[{"grant_number":"742985","_id":"261099A6-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","name":"Tracing Evolution of Auxin Transport and Polarity in Plants"}],"publisher":"Oxford University Press","quality_controlled":"1","abstract":[{"lang":"eng","text":"Auxin and its PIN-FORMED (PIN) exporters are essential for tissue repair and regeneration in flowering plants. To gain insight into the evolution of this mechanism, we investigated their roles in leaves excised from Physcomitrium patens, a bryophyte known for its remarkable cell reprogramming capacity. We used various approaches to manipulate auxin levels, including exogenous application, pharmacological manipulations, and auxin biosynthesis mutants. We observed no significant effect on the rate of cell reprogramming. Rather, our analysis of auxin dynamics revealed a decrease in auxin levels upon excision, which was followed by a local increase before the reprogramming process began. Mutant analysis revealed that PpPINs are required for effective cell reprogramming, and endogenously expressed PpPINA-GFP accumulates polarly at sites that will develop into future filamentous stem cells. In addition, hyperpolarized PpPINA variants carrying mutated phosphorylation sites showed a marked delay in reprogramming, whereas endogenous or nonpolar versions do not have this effect. These results underscore that both the levels and the polarity of PpPINA are important for efficient cell reprogramming. Overall, these findings highlight the pivotal role of PIN polarity in plant regeneration. Furthermore, they suggest that understanding polarity mechanisms could have broader implications for improving regenerative processes across various plant species."}],"title":"Auxin fluctuation and PIN polarization in moss leaf cell reprogramming.","acknowledgement":"The authors sincerely thank Dr Barbara Kloeckener Gruissem’s time and efforts in critical reading and constructive advice on the manuscript. The authors gratefully acknowledge Dr. Eva Sundberg for generously providing transgenic plants to support this study.\r\nThis work was supported by the European Research Council Advanced Grant (ETAP-742985 to H.T. and J.F.) and the Taiwan National Science and Technology Council (NSTC 112-2311-B-005-008 to H.T. and L.-H.C.).","department":[{"_id":"JiFr"}],"article_type":"original","date_created":"2025-03-19T09:44:19Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","month":"03","_id":"19420","ec_funded":1,"publication":"Plant and Cell Physiology","oa_version":"None","date_updated":"2025-09-30T11:05:55Z","isi":1,"corr_author":"1","article_number":"pcaf008","author":[{"id":"19BDF720-25A0-11EA-AC6E-928F3DDC885E","first_name":"Han","full_name":"Tang, Han","last_name":"Tang","orcid":"0000-0001-6152-6637"},{"first_name":"L","full_name":"Chen, L","last_name":"Chen"},{"full_name":"Friml, Jiří","first_name":"Jiří","id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml","orcid":"0000-0002-8302-7596"}],"scopus_import":"1","publication_identifier":{"issn":["0032-0781"],"eissn":["1471-9053"]},"day":"05","article_processing_charge":"No","type":"journal_article","fulldoi":"https://doi.org/10.1093/pcp/pcaf008","external_id":{"isi":["001436802900001"],"pmid":["39829340"]},"date_published":"2025-03-05T00:00:00Z","pmid":1,"language":[{"iso":"eng"}]},{"ddc":["580"],"fulldoi":"https://doi.org/10.1038/s41477-025-01934-w","has_accepted_license":"1","external_id":{"pmid":["40044942"],"isi":["001437953800001"]},"date_published":"2025-03-05T00:00:00Z","pmid":1,"language":[{"iso":"eng"}],"article_number":"5207","author":[{"full_name":"Jia, G","first_name":"G","last_name":"Jia"},{"first_name":"G","full_name":"Chen, G","last_name":"Chen"},{"last_name":"Zhang","full_name":"Zhang, Z","first_name":"Z"},{"last_name":"Tian","full_name":"Tian, C","first_name":"C"},{"last_name":"Wang","full_name":"Wang, Y","first_name":"Y"},{"last_name":"Luo","full_name":"Luo, J","first_name":"J"},{"first_name":"K","full_name":"Zhang, K","last_name":"Zhang"},{"last_name":"Zhao","first_name":"X","full_name":"Zhao, X"},{"last_name":"Zhao","first_name":"X","full_name":"Zhao, X"},{"last_name":"Li","first_name":"Z","full_name":"Li, Z"},{"last_name":"Sun","first_name":"L","full_name":"Sun, L"},{"last_name":"Yang","first_name":"W","full_name":"Yang, W"},{"last_name":"Guo","first_name":"Y","full_name":"Guo, Y"},{"last_name":"Friml","orcid":"0000-0002-8302-7596","first_name":"Jiří","id":"4159519E-F248-11E8-B48F-1D18A9856A87","full_name":"Friml, Jiří"},{"full_name":"Gong, Z","first_name":"Z","last_name":"Gong"},{"full_name":"Zhang, J","first_name":"J","last_name":"Zhang"}],"publication_identifier":{"issn":["2055-0278"]},"scopus_import":"1","day":"05","article_processing_charge":"No","type":"journal_article","department":[{"_id":"JiFr"}],"article_type":"original","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2025-03-19T09:44:55Z","month":"03","_id":"19422","file_date_updated":"2025-11-12T07:50:45Z","intvolume":" 11","oa_version":"Submitted Version","publication":"Nature Plants","file":[{"relation":"main_file","checksum":"caeaf1a8bc3e1435e8c995d1d9df5390","file_size":2714177,"date_created":"2025-11-12T07:50:45Z","content_type":"application/pdf","access_level":"open_access","success":1,"date_updated":"2025-11-12T07:50:45Z","file_id":"20634","file_name":"2025_NaturePlants_Jia_submitted.pdf","creator":"dernst"}],"date_updated":"2025-11-12T07:52:06Z","isi":1,"oa":1,"volume":11,"year":"2025","citation":{"ieee":"G. Jia et al., “Ferredoxin-mediated mechanism for efficient nitrogen utilization in maize,” Nature Plants, vol. 11. Springer Nature, 2025.","short":"G. Jia, G. Chen, Z. Zhang, C. Tian, Y. Wang, J. Luo, K. Zhang, X. Zhao, X. Zhao, Z. Li, L. Sun, W. Yang, Y. Guo, J. Friml, Z. Gong, J. Zhang, Nature Plants 11 (2025).","apa":"Jia, G., Chen, G., Zhang, Z., Tian, C., Wang, Y., Luo, J., … Zhang, J. (2025). Ferredoxin-mediated mechanism for efficient nitrogen utilization in maize. Nature Plants. Springer Nature. https://doi.org/10.1038/s41477-025-01934-w","chicago":"Jia, G, G Chen, Z Zhang, C Tian, Y Wang, J Luo, K Zhang, et al. “Ferredoxin-Mediated Mechanism for Efficient Nitrogen Utilization in Maize.” Nature Plants. Springer Nature, 2025. https://doi.org/10.1038/s41477-025-01934-w.","mla":"Jia, G., et al. “Ferredoxin-Mediated Mechanism for Efficient Nitrogen Utilization in Maize.” Nature Plants, vol. 11, 5207, Springer Nature, 2025, doi:10.1038/s41477-025-01934-w.","ama":"Jia G, Chen G, Zhang Z, et al. Ferredoxin-mediated mechanism for efficient nitrogen utilization in maize. Nature Plants. 2025;11. doi:10.1038/s41477-025-01934-w","ista":"Jia G, Chen G, Zhang Z, Tian C, Wang Y, Luo J, Zhang K, Zhao X, Zhao X, Li Z, Sun L, Yang W, Guo Y, Friml J, Gong Z, Zhang J. 2025. Ferredoxin-mediated mechanism for efficient nitrogen utilization in maize. Nature Plants. 11, 5207."},"publication_status":"published","OA_place":"repository","OA_type":"green","doi":"10.1038/s41477-025-01934-w","status":"public","publisher":"Springer Nature","quality_controlled":"1","abstract":[{"lang":"eng","text":"Nitrogen (N) is an essential macronutrient for plant development and, ultimately, yield. Identifying the genetic components and mechanisms underlying N use efficiency in maize (Zea mays L.) is thus of great importance. Nitrate (NO3−) is the preferred inorganic N source in maize. Here we performed a genome-wide association study of shoot NO3− accumulation in maize seedlings grown under low-NO3− conditions, identifying the ferredoxin family gene ZmFd4 as a major contributor to this trait. ZmFd4 interacts and co-localizes with nitrite reductases (ZmNiRs) in chloroplasts to promote their enzymatic activity. Furthermore, ZmFd4 forms a high-affinity heterodimer with its closest paralogue, ZmFd9, in a NO3−-sensitive manner. Although ZmFd4 exerts similar biochemical functions as ZmFd9, ZmFd4 and ZmFd9 interaction limits their ability to associate with ZmNiRs and stimulate their activity. Knockout lines for ZmFd4 with decreased NO3− contents exhibit more efficient NO3− assimilation, and field experiments show consistently improved N utilization and grain yield under N-deficient conditions. Our work thus provides molecular and mechanistic insights into the natural variation in N utilization, instrumental for genetic improvement of yield in maize and, potentially, in other crops."}],"title":"Ferredoxin-mediated mechanism for efficient nitrogen utilization in maize","acknowledgement":"We thank X. Yang for providing published inbred lines and helping with data analysis; and S. Huang, C. Jiang, G. Bi, C. Liu and S. Zhang for helpful discussions. The transgenic maize lines were generated by the Center for Crop Functional Genomics and Molecular Breeding of China Agricultural University. This work was supported by grants from the National Key Research and Development Program of China (2021YFF1000500 to J.Z.), the National Natural Science Foundation of China (32170265 and 32441022 to J.Z.), the Chinese Universities Scientific Fund (2024TC084 to J.Z.), the Pinduoduo-China Agricultural University Research Fund (PC2024B01005 to J.Z.), the Hainan Provincial Natural Science Foundation of China (323CXTD379 to J.Z.), and the Central Guidance on Local Science and Technology Development Fund of Shanxi Province (YDZJSX2024D040 to C.T. and J.Z.)."}]