[{"corr_author":"1","day":"10","author":[{"full_name":"Bahl, Monika","first_name":"Monika","last_name":"Bahl"},{"last_name":"Koutentakis","first_name":"Georgios","full_name":"Koutentakis, Georgios","id":"d7b23d3a-9e21-11ec-b482-f76739596b95"},{"id":"2E65BB0E-F248-11E8-B48F-1D18A9856A87","full_name":"Maslov, Mikhail","first_name":"Mikhail","last_name":"Maslov","orcid":"0000-0003-4074-2570"},{"last_name":"Jungnickel","first_name":"Tom","full_name":"Jungnickel, Tom"},{"last_name":"Gaßen","full_name":"Gaßen, Timo","first_name":"Timo"},{"first_name":"Mikhail","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","full_name":"Lemeshko, Mikhail","orcid":"0000-0002-6990-7802","last_name":"Lemeshko"},{"last_name":"Heckl","full_name":"Heckl, Oliver H.","first_name":"Oliver H."}],"OA_place":"publisher","project":[{"grant_number":"F100403","_id":"7c040762-9f16-11ee-852c-dd79eeee4ab3","name":"Coherent Optical Metrology Beyond Electric-Dipole-Allowed Transitions"}],"type":"journal_article","intvolume":"         8","date_created":"2026-03-22T23:04:32Z","oa_version":"Published Version","ddc":["530"],"article_type":"original","doi":"10.1088/2515-7647/ae3506","quality_controlled":"1","OA_type":"hybrid","abstract":[{"text":"Despite its pivotal role in optical manipulation, high capacity communications, and quantum information, a general measure of orbital angular momentum (OAM) in structured light remains elusive. In optical fields, where multiple vortices coexist, the local nature of vortex OAM and the absence of a common rotation axis make the total OAM of the field difficult to quantify. Here, we introduce the R index—a metric that captures the intrinsic OAM content of any structured optical field, from pure Laguerre–Gaussian modes to arbitrary multi vortex superpositions. Not only does this metric quantify the total OAM, it also assesses field purity, providing insight into the fidelity and robustness of the OAM generation. By unifying OAM characterization into a single figure of merit, the R index enables direct comparison across diverse beam profiles and facilitates the identification of optimal configurations for both foundational studies and applied technologies.","lang":"eng"}],"department":[{"_id":"MiLe"}],"title":"The R-index: A universal metric for evaluating OAM content and mode purity in optical fields","publication":"Journal of Physics: Photonics","_id":"21470","publisher":"IOP Publishing","month":"03","year":"2026","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"file_name":"2026_JPhysPhotonics_Bahl.pdf","file_size":1150404,"creator":"dernst","date_updated":"2026-03-23T13:24:01Z","file_id":"21476","content_type":"application/pdf","access_level":"open_access","relation":"main_file","success":1,"checksum":"0ec8a2d3f9efa704203a41f068344974","date_created":"2026-03-23T13:24:01Z"}],"fulldoi":"https://doi.org/10.1088/2515-7647/ae3506","language":[{"iso":"eng"}],"date_published":"2026-03-10T00:00:00Z","scopus_import":"1","volume":8,"article_processing_charge":"Yes (in subscription journal)","citation":{"chicago":"Bahl, Monika, Georgios Koutentakis, Mikhail Maslov, Tom Jungnickel, Timo Gaßen, Mikhail Lemeshko, and Oliver H. Heckl. “The R-Index: A Universal Metric for Evaluating OAM Content and Mode Purity in Optical Fields.” <i>Journal of Physics: Photonics</i>. IOP Publishing, 2026. <a href=\"https://doi.org/10.1088/2515-7647/ae3506\">https://doi.org/10.1088/2515-7647/ae3506</a>.","mla":"Bahl, Monika, et al. “The R-Index: A Universal Metric for Evaluating OAM Content and Mode Purity in Optical Fields.” <i>Journal of Physics: Photonics</i>, vol. 8, no. 1, 015071, IOP Publishing, 2026, doi:<a href=\"https://doi.org/10.1088/2515-7647/ae3506\">10.1088/2515-7647/ae3506</a>.","ieee":"M. Bahl <i>et al.</i>, “The R-index: A universal metric for evaluating OAM content and mode purity in optical fields,” <i>Journal of Physics: Photonics</i>, vol. 8, no. 1. IOP Publishing, 2026.","short":"M. Bahl, G. Koutentakis, M. Maslov, T. Jungnickel, T. Gaßen, M. Lemeshko, O.H. Heckl, Journal of Physics: Photonics 8 (2026).","apa":"Bahl, M., Koutentakis, G., Maslov, M., Jungnickel, T., Gaßen, T., Lemeshko, M., &#38; Heckl, O. H. (2026). The R-index: A universal metric for evaluating OAM content and mode purity in optical fields. <i>Journal of Physics: Photonics</i>. IOP Publishing. <a href=\"https://doi.org/10.1088/2515-7647/ae3506\">https://doi.org/10.1088/2515-7647/ae3506</a>","ista":"Bahl M, Koutentakis G, Maslov M, Jungnickel T, Gaßen T, Lemeshko M, Heckl OH. 2026. The R-index: A universal metric for evaluating OAM content and mode purity in optical fields. Journal of Physics: Photonics. 8(1), 015071.","ama":"Bahl M, Koutentakis G, Maslov M, et al. The R-index: A universal metric for evaluating OAM content and mode purity in optical fields. <i>Journal of Physics: Photonics</i>. 2026;8(1). doi:<a href=\"https://doi.org/10.1088/2515-7647/ae3506\">10.1088/2515-7647/ae3506</a>"},"acknowledgement":"This research was funded in whole or in part by the Austrian Science Fund (FWF) [10.55776/F1004]. For open access purposes, the author has applied a CC BY public copyright license to any author accepted manuscript version arising from this submission.","external_id":{"arxiv":["2508.12973"]},"file_date_updated":"2026-03-23T13:24:01Z","oa":1,"arxiv":1,"has_accepted_license":"1","date_updated":"2026-03-23T13:26:26Z","publication_identifier":{"eissn":["2515-7647"]},"issue":"1","publication_status":"published","article_number":"015071","status":"public"},{"corr_author":"1","day":"11","author":[{"first_name":"Sofia Maria","id":"a19ed178-1337-11ed-9389-c30ab879a82a","full_name":"Backlund, Sofia Maria","last_name":"Backlund"},{"id":"43161670-5719-11EA-8025-FABC3DDC885E","full_name":"Stankowski, Sean","first_name":"Sean","last_name":"Stankowski"},{"first_name":"Rosina Matilde","id":"9e668447-8c32-11ed-b0c7-8dc2d7b80803","full_name":"Soler Schaller, Rosina Matilde","last_name":"Soler Schaller"}],"OA_place":"publisher","intvolume":"       113","type":"journal_article","date_created":"2026-03-22T23:04:33Z","ddc":["580","570"],"oa_version":"Published Version","doi":"10.1002/ajb2.70175","article_type":"letter_note","quality_controlled":"1","OA_type":"hybrid","department":[{"_id":"NiBa"},{"_id":"GradSch"}],"title":"Seeds as space-time travelers: How does evolution balance the joint benefits and trade-offs of dormancy and dispersal?","publication":"American Journal of Botany","_id":"21471","month":"03","publisher":"Wiley","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"year":"2026","file":[{"content_type":"application/pdf","access_level":"open_access","creator":"dernst","file_name":"2026_AmericanJourBotany_Backlund.pdf","file_size":495080,"file_id":"21477","date_updated":"2026-03-23T14:01:44Z","date_created":"2026-03-23T14:01:44Z","relation":"main_file","checksum":"6116108a12c4a5cc91fc653d67885309","success":1}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","fulldoi":"https://doi.org/10.1002/ajb2.70175","date_published":"2026-03-11T00:00:00Z","language":[{"iso":"eng"}],"scopus_import":"1","acknowledgement":"We thank the Barton group at the Institute of Scienceand Technology Austria for many fruitful conversationsthat triggered the germination of the ideas and questions discussed here. N. H. Barton, P. Surendranadh, A. Pal,Z. Mérai, and two anonymous reviewers provided useful comments on the manuscript.","article_processing_charge":"No","volume":113,"citation":{"chicago":"Backlund, Sofia Maria, Sean Stankowski, and Rosina Matilde Soler Schaller. “Seeds as Space-Time Travelers: How Does Evolution Balance the Joint Benefits and Trade-Offs of Dormancy and Dispersal?” <i>American Journal of Botany</i>. Wiley, 2026. <a href=\"https://doi.org/10.1002/ajb2.70175\">https://doi.org/10.1002/ajb2.70175</a>.","mla":"Backlund, Sofia Maria, et al. “Seeds as Space-Time Travelers: How Does Evolution Balance the Joint Benefits and Trade-Offs of Dormancy and Dispersal?” <i>American Journal of Botany</i>, vol. 113, no. 3, e70175, Wiley, 2026, doi:<a href=\"https://doi.org/10.1002/ajb2.70175\">10.1002/ajb2.70175</a>.","ieee":"S. M. Backlund, S. Stankowski, and R. M. Soler Schaller, “Seeds as space-time travelers: How does evolution balance the joint benefits and trade-offs of dormancy and dispersal?,” <i>American Journal of Botany</i>, vol. 113, no. 3. Wiley, 2026.","short":"S.M. Backlund, S. Stankowski, R.M. Soler Schaller, American Journal of Botany 113 (2026).","apa":"Backlund, S. M., Stankowski, S., &#38; Soler Schaller, R. M. (2026). Seeds as space-time travelers: How does evolution balance the joint benefits and trade-offs of dormancy and dispersal? <i>American Journal of Botany</i>. Wiley. <a href=\"https://doi.org/10.1002/ajb2.70175\">https://doi.org/10.1002/ajb2.70175</a>","ama":"Backlund SM, Stankowski S, Soler Schaller RM. Seeds as space-time travelers: How does evolution balance the joint benefits and trade-offs of dormancy and dispersal? <i>American Journal of Botany</i>. 2026;113(3). doi:<a href=\"https://doi.org/10.1002/ajb2.70175\">10.1002/ajb2.70175</a>","ista":"Backlund SM, Stankowski S, Soler Schaller RM. 2026. Seeds as space-time travelers: How does evolution balance the joint benefits and trade-offs of dormancy and dispersal? American Journal of Botany. 113(3), e70175."},"oa":1,"has_accepted_license":"1","external_id":{"pmid":["41814642"]},"file_date_updated":"2026-03-23T14:01:44Z","date_updated":"2026-03-23T14:47:52Z","pmid":1,"publication_identifier":{"eissn":["1537-2197"],"issn":["0002-9122"]},"issue":"3","publication_status":"published","article_number":"e70175","status":"public"},{"year":"2026","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"month":"03","publisher":"Oxford University Press","_id":"21473","publication":"Brain Communications","oa":1,"has_accepted_license":"1","file_date_updated":"2026-03-23T14:27:39Z","acknowledgement":"We acknowledge the generosity of the patients, who contributed time and effort to take part in this study.","article_processing_charge":"Yes","citation":{"ieee":"A. R. Cardenas <i>et al.</i>, “Exercise enhances hippocampal-cortical ripple interactions in the human brain,” <i>Brain Communications</i>, vol. 8, no. 2. Oxford University Press, 2026.","chicago":"Cardenas, Araceli R., Juan F Ramirez Villegas, Christopher K. Kovach, Phillip E. Gander, Rachel C. Cole, Andrew J. Grossbach, Hiroto Kawasaki, et al. “Exercise Enhances Hippocampal-Cortical Ripple Interactions in the Human Brain.” <i>Brain Communications</i>. Oxford University Press, 2026. <a href=\"https://doi.org/10.1093/braincomms/fcag041\">https://doi.org/10.1093/braincomms/fcag041</a>.","mla":"Cardenas, Araceli R., et al. “Exercise Enhances Hippocampal-Cortical Ripple Interactions in the Human Brain.” <i>Brain Communications</i>, vol. 8, no. 2, fcag041, Oxford University Press, 2026, doi:<a href=\"https://doi.org/10.1093/braincomms/fcag041\">10.1093/braincomms/fcag041</a>.","ista":"Cardenas AR, Ramirez Villegas JF, Kovach CK, Gander PE, Cole RC, Grossbach AJ, Kawasaki H, Greenlee JDW, Howard MA, Nourski KV, Banks MI, Voss MW. 2026. Exercise enhances hippocampal-cortical ripple interactions in the human brain. Brain Communications. 8(2), fcag041.","ama":"Cardenas AR, Ramirez Villegas JF, Kovach CK, et al. Exercise enhances hippocampal-cortical ripple interactions in the human brain. <i>Brain Communications</i>. 2026;8(2). doi:<a href=\"https://doi.org/10.1093/braincomms/fcag041\">10.1093/braincomms/fcag041</a>","short":"A.R. Cardenas, J.F. Ramirez Villegas, C.K. Kovach, P.E. Gander, R.C. Cole, A.J. Grossbach, H. Kawasaki, J.D.W. Greenlee, M.A. Howard, K.V. Nourski, M.I. Banks, M.W. Voss, Brain Communications 8 (2026).","apa":"Cardenas, A. R., Ramirez Villegas, J. F., Kovach, C. K., Gander, P. E., Cole, R. C., Grossbach, A. J., … Voss, M. W. (2026). Exercise enhances hippocampal-cortical ripple interactions in the human brain. <i>Brain Communications</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/braincomms/fcag041\">https://doi.org/10.1093/braincomms/fcag041</a>"},"volume":8,"fulldoi":"https://doi.org/10.1093/braincomms/fcag041","date_published":"2026-03-09T00:00:00Z","language":[{"iso":"eng"}],"scopus_import":"1","file":[{"date_created":"2026-03-23T14:27:39Z","success":1,"checksum":"b5b45c16defeaf88056fc3b939bd0350","relation":"main_file","access_level":"open_access","content_type":"application/pdf","file_id":"21478","date_updated":"2026-03-23T14:27:39Z","file_size":33974419,"file_name":"2026_BrainCommunications_Cardenas.pdf","creator":"dernst"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2026-03-23T14:30:47Z","status":"public","article_number":"fcag041","publication_status":"published","issue":"2","publication_identifier":{"eissn":["2632-1297"]},"day":"09","corr_author":"1","date_created":"2026-03-22T23:04:34Z","intvolume":"         8","type":"journal_article","author":[{"last_name":"Cardenas","full_name":"Cardenas, Araceli R.","first_name":"Araceli R."},{"first_name":"Juan F","full_name":"Ramirez Villegas, Juan F","id":"44B06F76-F248-11E8-B48F-1D18A9856A87","last_name":"Ramirez Villegas"},{"first_name":"Christopher K.","full_name":"Kovach, Christopher K.","last_name":"Kovach"},{"last_name":"Gander","first_name":"Phillip E.","full_name":"Gander, Phillip E."},{"last_name":"Cole","first_name":"Rachel C.","full_name":"Cole, Rachel C."},{"last_name":"Grossbach","first_name":"Andrew J.","full_name":"Grossbach, Andrew J."},{"last_name":"Kawasaki","first_name":"Hiroto","full_name":"Kawasaki, Hiroto"},{"last_name":"Greenlee","first_name":"Jeremy D.W.","full_name":"Greenlee, Jeremy D.W."},{"full_name":"Howard, Matthew A.","first_name":"Matthew A.","last_name":"Howard"},{"full_name":"Nourski, Kirill V.","first_name":"Kirill V.","last_name":"Nourski"},{"last_name":"Banks","full_name":"Banks, Matthew I.","first_name":"Matthew I."},{"first_name":"Michelle W.","full_name":"Voss, Michelle W.","last_name":"Voss"}],"OA_place":"publisher","doi":"10.1093/braincomms/fcag041","article_type":"original","oa_version":"Published Version","PlanS_conform":"1","ddc":["570"],"department":[{"_id":"JoCs"}],"title":"Exercise enhances hippocampal-cortical ripple interactions in the human brain","abstract":[{"text":"Physical exercise acutely improves hippocampus-dependent memory. Whereas animal studies have offered cellular- and synaptic-level accounts of these effects, human neuroimaging studies show that exercise improves hippocampal-cortical connectivity at the macroscale level. However, the neurophysiological basis of exercise-induced effects on hippocampal-cortical circuits remains unknown. Experimental evidence supports the idea that hippocampal sharp wave-ripples (SWR) play a critical role in learning and memory. Coupling between SWRs in the hippocampus and neocortex may reflect modulations in inter-regional connectivity required by mnemonic processes. Here, we examine the hypothesis that exercise modulates hippocampal-cortical ripple dynamics in the human brain. We performed intracranial recordings in epilepsy patients undergoing pre-surgical evaluation, during awake resting state, before and after an exercise session. Exercise increased ripple rate in the hippocampus. Exercise also enhanced the coupling and phase-synchrony between cortical ripples in the limbic and the default mode (DM) cortical networks and hippocampal SWRs. Further, a higher heart rate during exercise, reflecting exercise intensity, was related to a subsequent increase in resting state ripples across specific cortical networks, including the DM network. These results offer the first direct evidence that a single exercise session elicits changes in ripple events, a well-established neurophysiological marker of mnemonic processing. The characterisation and anatomical distribution of the described modulation points to hippocampal ripples as a potential mechanism by which exercise elicits its reported short-term effects in cognition.","lang":"eng"}],"DOAJ_listed":"1","OA_type":"gold","quality_controlled":"1"},{"day":"04","intvolume":"       136","type":"journal_article","OA_place":"publisher","author":[{"first_name":"Matteo","full_name":"Votto, Matteo","last_name":"Votto"},{"last_name":"Ljubotina","orcid":"0000-0003-0038-7068","id":"F75EE9BE-5C90-11EA-905D-16643DDC885E","full_name":"Ljubotina, Marko","first_name":"Marko"},{"last_name":"Lancien","first_name":"Cécilia","full_name":"Lancien, Cécilia"},{"first_name":"J. Ignacio","full_name":"Cirac, J. Ignacio","last_name":"Cirac"},{"last_name":"Zoller","full_name":"Zoller, Peter","first_name":"Peter"},{"last_name":"Serbyn","orcid":"0000-0002-2399-5827","full_name":"Serbyn, Maksym","id":"47809E7E-F248-11E8-B48F-1D18A9856A87","first_name":"Maksym"},{"last_name":"Piroli","first_name":"Lorenzo","full_name":"Piroli, Lorenzo"},{"last_name":"Vermersch","first_name":"Benoît","full_name":"Vermersch, Benoît"}],"date_created":"2026-03-23T14:56:32Z","PlanS_conform":"1","ddc":["530"],"oa_version":"Published Version","article_type":"original","doi":"10.1103/rbg2-f61m","quality_controlled":"1","OA_type":"hybrid","title":"Learning mixed quantum states in large-scale experiments","department":[{"_id":"MaSe"}],"abstract":[{"text":"We present and test a protocol to learn the matrix-product operator (MPO) representation of an experimentally prepared quantum state. The protocol takes as input classical shadows corresponding to local randomized measurements, and outputs the tensors of an MPO maximizing a suitably defined fidelity with the experimental state. The tensor optimization is carried out sequentially, similarly to the well-known density matrix renormalization group algorithm. Our approach is provably efficient under certain technical conditions expected to be met in short-range correlated states and in typical noisy experimental settings. Under the same conditions, we also provide an efficient scheme to estimate fidelities between the learned and the experimental states. We experimentally demonstrate our protocol by learning entangled quantum states of up to N = 96 qubits in a superconducting quantum processor. Our method upgrades classical shadows to large-scale quantum computation and simulation experiments.","lang":"eng"}],"_id":"21480","publication":"Physical Review Letters","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"year":"2026","publisher":"American Physical Society","month":"03","fulldoi":"https://doi.org/10.1103/rbg2-f61m","date_published":"2026-03-04T00:00:00Z","language":[{"iso":"eng"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"checksum":"12b16ce2d49c62b2909da95121bfaadb","success":1,"relation":"main_file","date_created":"2026-03-23T15:35:27Z","file_id":"21491","date_updated":"2026-03-23T15:35:27Z","creator":"dernst","file_size":500041,"file_name":"2026_PhysicalReviewLetters_Votto.pdf","access_level":"open_access","content_type":"application/pdf"}],"external_id":{"arxiv":["2507.12550"]},"file_date_updated":"2026-03-23T15:35:27Z","arxiv":1,"has_accepted_license":"1","oa":1,"article_processing_charge":"Yes (in subscription journal)","citation":{"ista":"Votto M, Ljubotina M, Lancien C, Cirac JI, Zoller P, Serbyn M, Piroli L, Vermersch B. 2026. Learning mixed quantum states in large-scale experiments. Physical Review Letters. 136(9), 090801.","ama":"Votto M, Ljubotina M, Lancien C, et al. Learning mixed quantum states in large-scale experiments. <i>Physical Review Letters</i>. 2026;136(9). doi:<a href=\"https://doi.org/10.1103/rbg2-f61m\">10.1103/rbg2-f61m</a>","short":"M. Votto, M. Ljubotina, C. Lancien, J.I. Cirac, P. Zoller, M. Serbyn, L. Piroli, B. Vermersch, Physical Review Letters 136 (2026).","apa":"Votto, M., Ljubotina, M., Lancien, C., Cirac, J. I., Zoller, P., Serbyn, M., … Vermersch, B. (2026). Learning mixed quantum states in large-scale experiments. <i>Physical Review Letters</i>. American Physical Society. <a href=\"https://doi.org/10.1103/rbg2-f61m\">https://doi.org/10.1103/rbg2-f61m</a>","ieee":"M. Votto <i>et al.</i>, “Learning mixed quantum states in large-scale experiments,” <i>Physical Review Letters</i>, vol. 136, no. 9. American Physical Society, 2026.","chicago":"Votto, Matteo, Marko Ljubotina, Cécilia Lancien, J. Ignacio Cirac, Peter Zoller, Maksym Serbyn, Lorenzo Piroli, and Benoît Vermersch. “Learning Mixed Quantum States in Large-Scale Experiments.” <i>Physical Review Letters</i>. American Physical Society, 2026. <a href=\"https://doi.org/10.1103/rbg2-f61m\">https://doi.org/10.1103/rbg2-f61m</a>.","mla":"Votto, Matteo, et al. “Learning Mixed Quantum States in Large-Scale Experiments.” <i>Physical Review Letters</i>, vol. 136, no. 9, 090801, American Physical Society, 2026, doi:<a href=\"https://doi.org/10.1103/rbg2-f61m\">10.1103/rbg2-f61m</a>."},"volume":136,"acknowledgement":"We acknowledge insightful discussions with Antoine Browaeys, Mari Carmen Bañuls, Soonwon Choi, Thierry Lahaye, Daniel Stilck-França, Georgios Styliaris, and Xavier Waintal. The experimental data have been collected using the Qiskit library [103], and have been postprocessed using the RandomMeas [104] and ITensor [105] libraries. The work of M. V. and B. V. was funded by the French National Research Agency via the JCJC project QRand (No. ANR-20-CE47-0005), and via the research programs Plan France 2030 EPIQ (No. ANR-22-\r\nPETQ-0007), QUBITAF (No. ANR-22-PETQ-0004), and HQI (No. ANR-22-PNCQ-0002). We acknowledge the use of IBM Quantum Credits for this work. M. L. acknowledges support by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy—EXC-2111–390814868. The work of C. L. was funded by the French National Research Agency via the PRC project ESQuisses (No. ANR-20-CE47-0014-01). J. I. C.\r\nacknowledges funding from the Federal Ministry of Education and Research Germany (BMBF) via the project FermiQP (No. 13N15889). Work at MPQ is part of the Munich Quantum Valley, which is supported by the Bavarian state government with funds from the Hightech Agenda\r\nBayern Plus. P. Z. acknowledges support by the European Union’s Horizon Europe research and innovation program under Grant Agreement No. 101113690 (PASQANS2). The work of L. P. was funded by the European Union (ERC, QUANTHEM, No. 101114881). We acknowledge support\r\nby the Erwin Schrödinger International Institute for Mathematics and Physics (ESI).","date_updated":"2026-03-23T15:39:34Z","issue":"9","publication_identifier":{"issn":["0031-9007"],"eissn":["1079-7114"]},"status":"public","article_number":"090801","publication_status":"published"},{"date_created":"2026-03-23T14:58:03Z","intvolume":"       707","type":"journal_article","project":[{"_id":"bd9b2118-d553-11ed-ba76-db24564edfea","grant_number":"101076224","name":"Young galaxies as tracers and agents of cosmic reionization"}],"OA_place":"publisher","author":[{"first_name":"Ivan","id":"9a9394cb-3200-11ee-973b-f5ba2a8b16e4","full_name":"Kramarenko, Ivan","orcid":"0000-0001-5346-6048","last_name":"Kramarenko"},{"last_name":"Rosdahl","full_name":"Rosdahl, J.","first_name":"J."},{"full_name":"Blaizot, J.","first_name":"J.","last_name":"Blaizot"},{"orcid":"0000-0003-2871-127X","last_name":"Matthee","full_name":"Matthee, Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720","first_name":"Jorryt J"},{"full_name":"Katz, H.","first_name":"H.","last_name":"Katz"},{"last_name":"Di Cesare","id":"2d002343-372f-11ef-98ec-a164d20427cb","full_name":"Di Cesare, Claudia","first_name":"Claudia"}],"day":"05","corr_author":"1","department":[{"_id":"JoMa"}],"title":"H α as a tracer of star formation in the SPHINX cosmological simulations","abstract":[{"text":"The Hα emission line in galaxies is a powerful tracer of their recent star formation activity. With the advent of JWST, we are now able to routinely observe Hα in galaxies at high redshift (z ≳ 3) and thus measure their star formation rates (SFRs). However, using classical SFR(Hα) calibrations to derive the SFRs leads to biased results because high-redshift galaxies are commonly characterized by low metallicities and bursty star formation histories, affecting the conversion factor between the Hα luminosity (LHα) and the SFR. We developed a set of new SFR(Hα) calibrations that allowed us to predict the SFRs of Hα-emitters at z ≳ 3 with very little error. We used the SPHINX cosmological simulations to select a sample of star-forming galaxies representative of the Hα-emitter population observed with JWST. We then derived linear corrections to the classical SFR(Hα) calibrations that took variations in the physical properties (e.g., stellar metallicities) among individual galaxies into account. We obtained two new SFR(Hα) calibrations that compared to the classical calibrations reduce the root mean squared error (RMSE) in the predicted SFRs by ΔRMSE ≈ 0.04 dex and ΔRMSE ≈ 0.06 dex, respectively. Using the recent JWST NIRCam/grism observations of Hα-emitters at z ∼ 6, we show that the new calibrations affect the high-redshift galaxy population statistics: (i) the estimated cosmic SFR density decreases by ΔρSFR ≈ 12%, and (ii) the observed slope of the star formation main sequence increases by Δ∂logSFR/∂logM★ = 0.08 ± 0.02.","lang":"eng"}],"DOAJ_listed":"1","OA_type":"diamond","quality_controlled":"1","doi":"10.1051/0004-6361/202557114","article_type":"original","PlanS_conform":"1","ddc":["520"],"oa_version":"Published Version","has_accepted_license":"1","arxiv":1,"oa":1,"file_date_updated":"2026-03-23T15:44:09Z","external_id":{"arxiv":["2509.05403"]},"acknowledgement":"We thank the anonymous referee for the insightful comments that helped improve the manuscript. We also thank Thibault Garel, Pascal Oesch, Irene Shivaei, Charlotte Simmonds, Andrew Hopkins, Daniel Schaerer, and Rashmi Gottumukkala for useful comments and productive discussions. We gratefully acknowledge support from the CBPsmn (PSMN, Pôle Scientifique de Modélisation Numérique) of the ENS de Lyon for the computing resources.\r\nFunded by the European Union (ERC, AGENTS, 101076224). Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Research Council. Neither the European Union nor the granting authority can be held responsible for them. This work made extensive use of several open-source software packages, and we gratefully acknowledge the efforts of their authors: numpy (Harris et al. 2020), astropy (Astropy Collaboration 2022), matplotlib (Hunter 2007), ipython (Perez & Granger 2007), and scikit-learn (Pedregosa et al. 2011).","citation":{"ama":"Kramarenko I, Rosdahl J, Blaizot J, Matthee JJ, Katz H, Di Cesare C. H α as a tracer of star formation in the SPHINX cosmological simulations. <i>Astronomy &#38; Astrophysics</i>. 2026;707. doi:<a href=\"https://doi.org/10.1051/0004-6361/202557114\">10.1051/0004-6361/202557114</a>","ista":"Kramarenko I, Rosdahl J, Blaizot J, Matthee JJ, Katz H, Di Cesare C. 2026. H α as a tracer of star formation in the SPHINX cosmological simulations. Astronomy &#38; Astrophysics. 707, A184.","apa":"Kramarenko, I., Rosdahl, J., Blaizot, J., Matthee, J. J., Katz, H., &#38; Di Cesare, C. (2026). H α as a tracer of star formation in the SPHINX cosmological simulations. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202557114\">https://doi.org/10.1051/0004-6361/202557114</a>","short":"I. Kramarenko, J. Rosdahl, J. Blaizot, J.J. Matthee, H. Katz, C. Di Cesare, Astronomy &#38; Astrophysics 707 (2026).","ieee":"I. Kramarenko, J. Rosdahl, J. Blaizot, J. J. Matthee, H. Katz, and C. Di Cesare, “H α as a tracer of star formation in the SPHINX cosmological simulations,” <i>Astronomy &#38; Astrophysics</i>, vol. 707. EDP Sciences, 2026.","mla":"Kramarenko, Ivan, et al. “H α as a Tracer of Star Formation in the SPHINX Cosmological Simulations.” <i>Astronomy &#38; Astrophysics</i>, vol. 707, A184, EDP Sciences, 2026, doi:<a href=\"https://doi.org/10.1051/0004-6361/202557114\">10.1051/0004-6361/202557114</a>.","chicago":"Kramarenko, Ivan, J. Rosdahl, J. Blaizot, Jorryt J Matthee, H. Katz, and Claudia Di Cesare. “H α as a Tracer of Star Formation in the SPHINX Cosmological Simulations.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2026. <a href=\"https://doi.org/10.1051/0004-6361/202557114\">https://doi.org/10.1051/0004-6361/202557114</a>."},"article_processing_charge":"No","volume":707,"fulldoi":"https://doi.org/10.1051/0004-6361/202557114","language":[{"iso":"eng"}],"date_published":"2026-03-05T00:00:00Z","file":[{"file_name":"2026_AstronomyAstrophysics_Kramarenko.pdf","file_size":904565,"creator":"dernst","date_updated":"2026-03-23T15:44:09Z","file_id":"21492","content_type":"application/pdf","access_level":"open_access","relation":"main_file","checksum":"7429076b381dd498084f40ffd199e714","success":1,"date_created":"2026-03-23T15:44:09Z"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"year":"2026","month":"03","publisher":"EDP Sciences","_id":"21481","publication":"Astronomy & Astrophysics","status":"public","publication_status":"published","article_number":"A184","publication_identifier":{"eissn":["1432-0746"],"issn":["0004-6361"]},"date_updated":"2026-03-23T15:46:31Z"},{"date_updated":"2026-03-23T15:59:11Z","publication_status":"published","article_number":"L012054","status":"public","publication_identifier":{"eissn":["2643-1564"]},"publisher":"American Physical Society","month":"03","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"year":"2026","publication":"Physical Review Research","_id":"21482","volume":8,"citation":{"ieee":"M. Hübl and C. P. Goodrich, “Entropic size control of self-assembled filaments,” <i>Physical Review Research</i>, vol. 8. American Physical Society, 2026.","mla":"Hübl, Maximilian, and Carl Peter Goodrich. “Entropic Size Control of Self-Assembled Filaments.” <i>Physical Review Research</i>, vol. 8, L012054, American Physical Society, 2026, doi:<a href=\"https://doi.org/10.1103/68rs-3qgn\">10.1103/68rs-3qgn</a>.","chicago":"Hübl, Maximilian, and Carl Peter Goodrich. “Entropic Size Control of Self-Assembled Filaments.” <i>Physical Review Research</i>. American Physical Society, 2026. <a href=\"https://doi.org/10.1103/68rs-3qgn\">https://doi.org/10.1103/68rs-3qgn</a>.","ama":"Hübl M, Goodrich CP. Entropic size control of self-assembled filaments. <i>Physical Review Research</i>. 2026;8. doi:<a href=\"https://doi.org/10.1103/68rs-3qgn\">10.1103/68rs-3qgn</a>","ista":"Hübl M, Goodrich CP. 2026. Entropic size control of self-assembled filaments. Physical Review Research. 8, L012054.","apa":"Hübl, M., &#38; Goodrich, C. P. (2026). Entropic size control of self-assembled filaments. <i>Physical Review Research</i>. American Physical Society. <a href=\"https://doi.org/10.1103/68rs-3qgn\">https://doi.org/10.1103/68rs-3qgn</a>","short":"M. Hübl, C.P. Goodrich, Physical Review Research 8 (2026)."},"article_processing_charge":"Yes","acknowledgement":"We thank Maitane Muñoz-Basagoiti for helpful discussions. The research was supported by the Gesellschaft für Forschungsförderung Niederösterreich under Project No. FTI23-G-011.","file_date_updated":"2026-03-23T15:53:29Z","has_accepted_license":"1","oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"checksum":"6d8a68e4a19f8dad5abdf75f72316f3d","success":1,"relation":"main_file","date_created":"2026-03-23T15:53:29Z","file_id":"21493","date_updated":"2026-03-23T15:53:29Z","creator":"dernst","file_name":"2026_PhysicalReviewResearch_Huebl.pdf","file_size":2680924,"access_level":"open_access","content_type":"application/pdf"}],"fulldoi":"https://doi.org/10.1103/68rs-3qgn","date_published":"2026-03-05T00:00:00Z","language":[{"iso":"eng"}],"doi":"10.1103/68rs-3qgn","article_type":"original","ddc":["530"],"oa_version":"Published Version","DOAJ_listed":"1","abstract":[{"lang":"eng","text":"Controlling the size and shape of assembled structures is a fundamental challenge in self-assembly and is highly relevant in material design and biology. Here, we show that specific but promiscuous short-range binding interactions make it possible to economically assemble linear filaments of user-defined length. Our approach leads to independent control over the mean and width of the filament size distribution and allows us to smoothly explore design trade-offs between assembly quality (spread in size) and cost (number of particle species). We employ a simple hierarchical assembly protocol to minimize assembly times and show that multiple stages of hierarchy make it possible to extend our approach to the assembly of higher-dimensional structures. Our work provides a conceptually simple solution to size control that is applicable to a broad range of systems, from DNA nanoparticles to supramolecular polymers and beyond."}],"department":[{"_id":"CaGo"},{"_id":"GradSch"}],"title":"Entropic size control of self-assembled filaments","OA_type":"gold","quality_controlled":"1","corr_author":"1","day":"05","date_created":"2026-03-23T14:58:31Z","author":[{"full_name":"Hübl, Maximilian","id":"5eb8629e-15b2-11ec-abd3-e6f3e5e01f32","first_name":"Maximilian","last_name":"Hübl"},{"first_name":"Carl Peter","full_name":"Goodrich, Carl Peter","id":"EB352CD2-F68A-11E9-89C5-A432E6697425","orcid":"0000-0002-1307-5074","last_name":"Goodrich"}],"OA_place":"publisher","project":[{"grant_number":"FTI23-G-011","_id":"8dd93da8-16d5-11f0-9cad-d2c70200d9a5","name":"Dynamically reconfigurable self-assembly with triangular DNA-origami bricks"}],"type":"journal_article","intvolume":"         8"},{"publication_status":"published","status":"public","publication_identifier":{"eissn":["1476-4687"],"issn":["0028-0836"]},"issue":"8106","ec_funded":1,"pmid":1,"date_updated":"2026-04-28T12:06:01Z","volume":651,"article_processing_charge":"Yes (via OA deal)","citation":{"ieee":"G. M. Grosjean <i>et al.</i>, “Adventitious carbon breaks symmetry in oxide contact electrification,” <i>Nature</i>, vol. 651, no. 8106. Springer Nature, pp. 626–631, 2026.","mla":"Grosjean, Galien M., et al. “Adventitious Carbon Breaks Symmetry in Oxide Contact Electrification.” <i>Nature</i>, vol. 651, no. 8106, Springer Nature, 2026, pp. 626–31, doi:<a href=\"https://doi.org/10.1038/s41586-025-10088-w\">10.1038/s41586-025-10088-w</a>.","chicago":"Grosjean, Galien M, Markus Ostermann, Markus Sauer, Michael Hahn, Christian M. Pichler, Florian Fahrnberger, Felix Pertl, et al. “Adventitious Carbon Breaks Symmetry in Oxide Contact Electrification.” <i>Nature</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41586-025-10088-w\">https://doi.org/10.1038/s41586-025-10088-w</a>.","ista":"Grosjean GM, Ostermann M, Sauer M, Hahn M, Pichler CM, Fahrnberger F, Pertl F, Balazs D, Link MM, Kim SH, Schrader DL, Blanco A, Gracia F, Mujica N, Waitukaitis SR. 2026. Adventitious carbon breaks symmetry in oxide contact electrification. Nature. 651(8106), 626–631.","ama":"Grosjean GM, Ostermann M, Sauer M, et al. Adventitious carbon breaks symmetry in oxide contact electrification. <i>Nature</i>. 2026;651(8106):626-631. doi:<a href=\"https://doi.org/10.1038/s41586-025-10088-w\">10.1038/s41586-025-10088-w</a>","apa":"Grosjean, G. M., Ostermann, M., Sauer, M., Hahn, M., Pichler, C. M., Fahrnberger, F., … Waitukaitis, S. R. (2026). Adventitious carbon breaks symmetry in oxide contact electrification. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41586-025-10088-w\">https://doi.org/10.1038/s41586-025-10088-w</a>","short":"G.M. Grosjean, M. Ostermann, M. Sauer, M. Hahn, C.M. Pichler, F. Fahrnberger, F. Pertl, D. Balazs, M.M. Link, S.H. Kim, D.L. Schrader, A. Blanco, F. Gracia, N. Mujica, S.R. Waitukaitis, Nature 651 (2026) 626–631."},"acknowledgement":"This project has received support from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement no. 949120) and from the Marie Skłodowska-Curie programme (grant agreement no. 754411). We acknowledge the state of Lower Austria and the European Regional Development Fund under grant no. WST3-F-542638/004-2021. N.M. acknowledges support from grant Fondecyt 1221597. G.G. is a Serra Húnter fellow. This research was supported by the Scientific Service Units of the Institute of Science and Technology Austria through resources provided by the Miba Machine Shop, Nanofabrication Facility, Scientific Computing facility and Lab Support Facility. We thank the Modic group for the use of the Laue camera, T. Zauner for the photography of the experimental set-up and R. Möller for insightful discussions. Open access funding provided by Institute of Science and Technology (IST Austria).","external_id":{"pmid":["41851325"]},"file_date_updated":"2026-03-24T06:57:08Z","has_accepted_license":"1","oa":1,"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","file":[{"date_created":"2026-03-24T06:57:08Z","checksum":"dafef9ed575b44be4263e948a47ae056","success":1,"relation":"main_file","access_level":"open_access","content_type":"application/pdf","file_id":"21494","date_updated":"2026-03-24T06:57:08Z","creator":"dernst","file_size":12245694,"file_name":"2026_Nature_Grosjean.pdf"}],"date_published":"2026-03-18T00:00:00Z","fulldoi":"https://doi.org/10.1038/s41586-025-10088-w","language":[{"iso":"eng"}],"publisher":"Springer Nature","month":"03","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"year":"2026","publication":"Nature","_id":"21485","abstract":[{"text":"Insulating oxides are among the most abundant solid materials in the universe1,2,3. Of the many ways in which they influence natural phenomena, perhaps the most consequential is their capacity to transfer electrical charge during contact4,5,6,7,8,9,10—which occurs even between samples of the same oxide—yet the symmetry-breaking parameter that causes this remains unidentified11,12. Here we show that adventitious carbonaceous molecules adsorbed from the environment are the symmetry-breaking factor in same-material oxide contact electrification (CE). We use acoustic levitation to measure charge exchange between a sphere and a plate composed of identical amorphous silicon dioxide (SiO2). Although charging polarity is random for co-prepared samples, we control it with baking or plasma treatment. Observing the charge-exchange relaxation afterwards, we see dynamics over a timescale of hours and connect this directly to the presence of adventitious carbon with time-of-flight mass spectrometry, low-energy ion scattering and infrared spectroscopy. Going further, we confirm that adventitious carbon can even determine charge exchange among different oxides. Our results identify the symmetry-breaking parameter that causes insulating oxides to exchange charge in settings ranging from desert sands4 to volcanic plumes5,6, while simultaneously highlighting an overlooked factor in CE more broadly.","lang":"eng"}],"acknowledged_ssus":[{"_id":"M-Shop"},{"_id":"NanoFab"},{"_id":"ScienComp"},{"_id":"LifeSc"}],"title":"Adventitious carbon breaks symmetry in oxide contact electrification","department":[{"_id":"ScWa"},{"_id":"GradSch"},{"_id":"LifeSc"}],"quality_controlled":"1","OA_type":"hybrid","article_type":"original","doi":"10.1038/s41586-025-10088-w","PlanS_conform":"1","ddc":["540"],"oa_version":"Published Version","date_created":"2026-03-23T15:04:00Z","author":[{"last_name":"Grosjean","orcid":"0000-0001-5154-417X","full_name":"Grosjean, Galien M","id":"0C5FDA4A-9CF6-11E9-8939-FF05E6697425","first_name":"Galien M"},{"last_name":"Ostermann","first_name":"Markus","full_name":"Ostermann, Markus"},{"first_name":"Markus","full_name":"Sauer, Markus","last_name":"Sauer"},{"last_name":"Hahn","first_name":"Michael","full_name":"Hahn, Michael"},{"first_name":"Christian M.","full_name":"Pichler, Christian M.","last_name":"Pichler"},{"first_name":"Florian","full_name":"Fahrnberger, Florian","last_name":"Fahrnberger"},{"last_name":"Pertl","orcid":"0000-0003-0463-5794","first_name":"Felix","full_name":"Pertl, Felix","id":"6313aec0-15b2-11ec-abd3-ed67d16139af"},{"last_name":"Balazs","orcid":"0000-0001-7597-043X","full_name":"Balazs, Daniel","id":"302BADF6-85FC-11EA-9E3B-B9493DDC885E","first_name":"Daniel"},{"first_name":"Mason M.","full_name":"Link, Mason M.","last_name":"Link"},{"full_name":"Kim, Seong H.","first_name":"Seong H.","last_name":"Kim"},{"full_name":"Schrader, Devin L.","first_name":"Devin L.","last_name":"Schrader"},{"last_name":"Blanco","first_name":"Adriana","full_name":"Blanco, Adriana"},{"full_name":"Gracia, Francisco","first_name":"Francisco","last_name":"Gracia"},{"first_name":"Nicolás","full_name":"Mujica, Nicolás","last_name":"Mujica"},{"orcid":"0000-0002-2299-3176","last_name":"Waitukaitis","full_name":"Waitukaitis, Scott R","id":"3A1FFC16-F248-11E8-B48F-1D18A9856A87","first_name":"Scott R"}],"OA_place":"publisher","project":[{"_id":"0aa60e99-070f-11eb-9043-a6de6bdc3afa","grant_number":"949120","name":"Tribocharge: a multi-scale approach to an enduring problem in physics","call_identifier":"H2020"},{"call_identifier":"H2020","grant_number":"754411","_id":"260C2330-B435-11E9-9278-68D0E5697425","name":"ISTplus - Postdoctoral Fellowships"}],"intvolume":"       651","type":"journal_article","page":"626-631","corr_author":"1","related_material":{"link":[{"description":"News on ISTA website","url":"https://ista.ac.at/en/news/colliding-dust-and-the-sparks-of-creation/","relation":"press_release"}]},"day":"18"},{"article_type":"original","doi":"10.1016/j.cub.2026.02.023","ddc":["580"],"oa_version":"Published Version","PlanS_conform":"1","acknowledged_ssus":[{"_id":"MassSpec"},{"_id":"Bio"},{"_id":"LifeSc"}],"abstract":[{"text":"Auxin canalization is a self-organizing process that governs the flexible formation of vasculature by reinforcing the formation of auxin transport channels. A key prerequisite is the feedback between auxin signaling and directional auxin transport, mediated by PIN transporters. Despite the developmental importance of canalization, the molecular components linking auxin perception to the regulation of PIN auxin transporters remain poorly understood. Here, we identify TOW, a novel and essential component of auxin canalization that links intracellular auxin signaling with cell surface auxin perception. TOW is regulated downstream of TIR1/AFB-Aux/IAA-WRKY23 transcriptional auxin signaling. tow mutants exhibit defects in regeneration and de novo vasculature formation, along with impaired formation of polarized, PIN-expressing auxin channels. At the subcellular level, these mutants display disrupted auxin-induced PIN polarization and altered PIN endocytic trafficking dynamics. TOW localizes predominantly to the plasma membrane, where it interacts with receptor-like kinases involved in auxin canalization, including the TMK1 auxin co-receptor and the CAMEL-CANAR complex. TOW promotes PIN interaction with these kinases and stabilizes PINs at the cell surface. Together, our findings identify TOW as a molecular link between intracellular and cell surface auxin signaling mechanisms that converge on PIN trafficking and polarity, providing new insights into how auxin signaling regulates directional auxin transport for the self-organizing formation of vasculature during flexible plant development.","lang":"eng"}],"title":"Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin canalization","department":[{"_id":"JiFr"}],"quality_controlled":"1","OA_type":"hybrid","page":"1468-1480.e6","corr_author":"1","day":"23","date_created":"2026-03-23T15:11:16Z","OA_place":"publisher","author":[{"last_name":"Li","first_name":"Mingyue","id":"01f96916-0235-11eb-9379-a323192643b7","full_name":"Li, Mingyue"},{"full_name":"Rydza, Nikola","first_name":"Nikola","last_name":"Rydza"},{"full_name":"Mazur, Ewa","first_name":"Ewa","last_name":"Mazur"},{"last_name":"Molnar","first_name":"Gergely","full_name":"Molnar, Gergely","id":"34F1AF46-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Nodzyński, Tomasz","first_name":"Tomasz","last_name":"Nodzyński"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","full_name":"Friml, Jiří","first_name":"Jiří","last_name":"Friml","orcid":"0000-0002-8302-7596"}],"project":[{"grant_number":"101142681","_id":"8f347782-16d5-11f0-9cad-8c19706ee739","name":"Cyclic nucleotides as second messengers in plants"},{"grant_number":"E271","_id":"bd906599-d553-11ed-ba76-abf8547645d7","name":"Identification of a novel regulator in auxin canalization"}],"intvolume":"        36","type":"journal_article","pmid":1,"date_updated":"2026-03-24T08:36:40Z","publication_status":"published","status":"public","publication_identifier":{"issn":["0960-9822"]},"issue":"6","publisher":"Elsevier","month":"03","year":"2026","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"publication":"Current Biology","_id":"21490","article_processing_charge":"Yes (via OA deal)","volume":36,"citation":{"apa":"Li, M., Rydza, N., Mazur, E., Molnar, G., Nodzyński, T., &#38; Friml, J. (2026). Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin canalization. <i>Current Biology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.cub.2026.02.023\">https://doi.org/10.1016/j.cub.2026.02.023</a>","short":"M. Li, N. Rydza, E. Mazur, G. Molnar, T. Nodzyński, J. Friml, Current Biology 36 (2026) 1468–1480.e6.","ista":"Li M, Rydza N, Mazur E, Molnar G, Nodzyński T, Friml J. 2026. Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin canalization. Current Biology. 36(6), 1468–1480.e6.","ama":"Li M, Rydza N, Mazur E, Molnar G, Nodzyński T, Friml J. Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin canalization. <i>Current Biology</i>. 2026;36(6):1468-1480.e6. doi:<a href=\"https://doi.org/10.1016/j.cub.2026.02.023\">10.1016/j.cub.2026.02.023</a>","mla":"Li, Mingyue, et al. “Receptor-like-Kinase-Interacting Protein TOW Stabilizes PIN Transporters for Auxin Canalization.” <i>Current Biology</i>, vol. 36, no. 6, Elsevier, 2026, p. 1468–1480.e6, doi:<a href=\"https://doi.org/10.1016/j.cub.2026.02.023\">10.1016/j.cub.2026.02.023</a>.","chicago":"Li, Mingyue, Nikola Rydza, Ewa Mazur, Gergely Molnar, Tomasz Nodzyński, and Jiří Friml. “Receptor-like-Kinase-Interacting Protein TOW Stabilizes PIN Transporters for Auxin Canalization.” <i>Current Biology</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.cub.2026.02.023\">https://doi.org/10.1016/j.cub.2026.02.023</a>.","ieee":"M. Li, N. Rydza, E. Mazur, G. Molnar, T. Nodzyński, and J. Friml, “Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin canalization,” <i>Current Biology</i>, vol. 36, no. 6. Elsevier, p. 1468–1480.e6, 2026."},"acknowledgement":"We thank Dr. Z. Ge (ISTA) for providing vectors for the CRISPR-Cas9 system, Dr. Armel Nicolas and Dr. Bella Bruszel for phosphoproteomic analysis, Prof. Michael Wrzaczek (Czech Academy of Sciences, Czechia) for valuable suggestions, and Prof. Maciek Adamowski (University of Gdańsk) for technical assistance. We also acknowledge the support of the Mass Spectrometry and Proteomics Facility, the Imaging & Optics Facility, and the Lab Support Facility at the Institute of Science and Technology Austria. This research was supported by the Scientific Service Units (SSU) of ISTA, utilizing resources provided by the Imaging & Optics Facility (IOF) and the Lab Support Facility (LSF). The work conducted by the Friml group was funded by the European Research Council (ERC) under grant agreement no. 101142681 (CYNIPS) and by the Austrian Science Fund (FWF) under project ESP271. We acknowledge the core facility CELLIM supported by MEYS CR (LM2023050 Czech-BioImaging) and the Plant Sciences Core Facility of CEITEC Masaryk University. E.M. received support from the National Science Centre (NCN), Poland, through the OPUS call within the Weave programme (grant no. 2021/43/I/NZ1/01835). T.N. received support from TowArds Next GENeration Crops, reg. no. CZ.02.01.01/00/22_008/0004581 of the ERDF Programme Johannes Amos Comenius.","file_date_updated":"2026-03-24T08:34:37Z","external_id":{"pmid":["41831441"]},"has_accepted_license":"1","oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"file_size":12986894,"file_name":"2026_CurrentBiology_Li.pdf","creator":"dernst","file_id":"21496","date_updated":"2026-03-24T08:34:37Z","content_type":"application/pdf","access_level":"open_access","relation":"main_file","success":1,"checksum":"fe6c41fdab58a55df5f2a5860c02acdc","date_created":"2026-03-24T08:34:37Z"}],"fulldoi":"https://doi.org/10.1016/j.cub.2026.02.023","date_published":"2026-03-23T00:00:00Z","language":[{"iso":"eng"}]},{"title":"Computational variant predictors for pharmacogenomics: From evaluation of single alleles to assessment of adverse drug reactions to antidepressants","department":[{"_id":"MaRo"}],"abstract":[{"text":"Currently, pharmacogenetics relies on partially annotated star alleles, leaving novel variants and complex haplotypes uninterpretable. Computational scoring frameworks could overcome these limitations. Here, we comprehensively evaluated the ability of existing (CADD, FATHMM-XF, PROVEAN, MutationAssessor, SIFT, PhyloP100, APF, APF2) and novel (PharmGScore and PharmMLScore) variant effect predictors to assess pharmacogenetic alleles in multiple scenarios. Altogether we analyzed 541 PharmVar alleles, high‑throughput CYP2C9 and CYP2C19 mutational maps, and 200 642 UK Biobank exomes linked with health records containing antidepressant treatment outcomes. Many evaluated tools, especially ensemble frameworks, matched or exceeded star allele classifications (ROC‑AUC up to 0.85 for allele definitions, 0.95 in vitro; TPR up to 0.99 for exomes) and accurately predicted severe antidepressant adverse events for carriers of deleterious variants in CYP2C19 (OR 1.20–1.35). Our findings show that computational predictors deliver star allele accuracy while overcoming their limitations. With additional validation, computational tools could enhance clinical decision frameworks by enabling continuous scoring, incorporating previously unknown variants, and providing genome-wide applicability.","lang":"eng"}],"OA_type":"hybrid","quality_controlled":"1","article_type":"original","doi":"10.1038/s41397-026-00399-0","oa_version":"Published Version","ddc":["570"],"date_created":"2026-03-29T22:07:08Z","type":"journal_article","intvolume":"        26","OA_place":"publisher","author":[{"last_name":"Hajto","first_name":"Jacek","full_name":"Hajto, Jacek"},{"last_name":"Piechota","full_name":"Piechota, Marcin","first_name":"Marcin"},{"orcid":"0000-0002-5636-9259","last_name":"Krätschmer","first_name":"Ilse","full_name":"Krätschmer, Ilse","id":"30d4014e-7753-11eb-b44b-db6d61112e73"},{"full_name":"Konowalska, Paula","first_name":"Paula","last_name":"Konowalska"},{"full_name":"Boyle, Gabriel E.","first_name":"Gabriel E.","last_name":"Boyle"},{"last_name":"Fowler","full_name":"Fowler, Douglas M.","first_name":"Douglas M."},{"full_name":"Borczyk, Malgorzata","first_name":"Malgorzata","last_name":"Borczyk"},{"full_name":"Korostynski, Michal","first_name":"Michal","last_name":"Korostynski"}],"day":"09","status":"public","article_number":"8","publication_status":"published","issue":"2","publication_identifier":{"eissn":["1473-1150"],"issn":[" 1470-269X"]},"pmid":1,"date_updated":"2026-03-30T07:10:50Z","has_accepted_license":"1","oa":1,"file_date_updated":"2026-03-30T07:04:08Z","external_id":{"pmid":["41803106"]},"acknowledgement":"This research has been conducted using the UK Biobank Resource under Application Number 62979. We are grateful to the UK Biobank and all its voluntary participants. This work used data provided by patients and collected by the NHS as part of their care and support.\r\n\r\nThis study was funded by the National Science Center, Poland: PRELUDIUM BIS-3 grant no. 2021/43/O/NZ7/01187 (development and benchmarking of variant scores) and SONATINA 5 grant 2021/40/C/NZ2/00218 (UKB analyses). Additional support came from the statutory funds of the Maj Institute of Pharmacology PAS. We gratefully acknowledge Poland’s high-performance Infrastructure PLGrid ACK Cyfronet AGH, for providing computer facilities and support within computational grant no PLG/2022/015861. DMF and GEB were funded by NIH grants NIH R35GM152106 and UM1HG011969.","article_processing_charge":"Yes (in subscription journal)","citation":{"mla":"Hajto, Jacek, et al. “Computational Variant Predictors for Pharmacogenomics: From Evaluation of Single Alleles to Assessment of Adverse Drug Reactions to Antidepressants.” <i>Pharmacogenomics Journal</i>, vol. 26, no. 2, 8, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41397-026-00399-0\">10.1038/s41397-026-00399-0</a>.","chicago":"Hajto, Jacek, Marcin Piechota, Ilse Krätschmer, Paula Konowalska, Gabriel E. Boyle, Douglas M. Fowler, Malgorzata Borczyk, and Michal Korostynski. “Computational Variant Predictors for Pharmacogenomics: From Evaluation of Single Alleles to Assessment of Adverse Drug Reactions to Antidepressants.” <i>Pharmacogenomics Journal</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41397-026-00399-0\">https://doi.org/10.1038/s41397-026-00399-0</a>.","ieee":"J. Hajto <i>et al.</i>, “Computational variant predictors for pharmacogenomics: From evaluation of single alleles to assessment of adverse drug reactions to antidepressants,” <i>Pharmacogenomics Journal</i>, vol. 26, no. 2. Springer Nature, 2026.","apa":"Hajto, J., Piechota, M., Krätschmer, I., Konowalska, P., Boyle, G. E., Fowler, D. M., … Korostynski, M. (2026). Computational variant predictors for pharmacogenomics: From evaluation of single alleles to assessment of adverse drug reactions to antidepressants. <i>Pharmacogenomics Journal</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41397-026-00399-0\">https://doi.org/10.1038/s41397-026-00399-0</a>","short":"J. Hajto, M. Piechota, I. Krätschmer, P. Konowalska, G.E. Boyle, D.M. Fowler, M. Borczyk, M. Korostynski, Pharmacogenomics Journal 26 (2026).","ama":"Hajto J, Piechota M, Krätschmer I, et al. Computational variant predictors for pharmacogenomics: From evaluation of single alleles to assessment of adverse drug reactions to antidepressants. <i>Pharmacogenomics Journal</i>. 2026;26(2). doi:<a href=\"https://doi.org/10.1038/s41397-026-00399-0\">10.1038/s41397-026-00399-0</a>","ista":"Hajto J, Piechota M, Krätschmer I, Konowalska P, Boyle GE, Fowler DM, Borczyk M, Korostynski M. 2026. Computational variant predictors for pharmacogenomics: From evaluation of single alleles to assessment of adverse drug reactions to antidepressants. Pharmacogenomics Journal. 26(2), 8."},"volume":26,"scopus_import":"1","fulldoi":"https://doi.org/10.1038/s41397-026-00399-0","language":[{"iso":"eng"}],"date_published":"2026-03-09T00:00:00Z","file":[{"content_type":"application/pdf","access_level":"open_access","file_size":2618963,"file_name":"2026_PharmacogenomicsJour_Hajto.pdf","creator":"dernst","file_id":"21506","date_updated":"2026-03-30T07:04:08Z","date_created":"2026-03-30T07:04:08Z","relation":"main_file","success":1,"checksum":"2fd3d7e48b779ac24245f6c35449b89a"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2026","tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)"},"month":"03","publisher":"Springer Nature","_id":"21503","publication":"Pharmacogenomics Journal"},{"page":"625-639.e8","day":"19","date_created":"2026-03-30T11:58:48Z","OA_place":"publisher","author":[{"last_name":"Weiss","first_name":"Joscha","full_name":"Weiss, Joscha"},{"last_name":"Vecchia","first_name":"Luca","full_name":"Vecchia, Luca"},{"last_name":"Domjan","first_name":"David","full_name":"Domjan, David"},{"first_name":"Simone","full_name":"Cavadini, Simone","last_name":"Cavadini"},{"last_name":"Sabantsev","first_name":"Anton","full_name":"Sabantsev, Anton"},{"last_name":"Kempf","first_name":"Georg","full_name":"Kempf, Georg"},{"last_name":"Pathare","first_name":"Ganesh R.","full_name":"Pathare, Ganesh R."},{"last_name":"Brackmann","full_name":"Brackmann, Klaus","first_name":"Klaus"},{"orcid":"0000-0002-6080-839X","last_name":"Michael","first_name":"Alicia","full_name":"Michael, Alicia","id":"6437c950-2a03-11ee-914d-d6476dd7b75c"},{"first_name":"Lukas","full_name":"Kater, Lukas","last_name":"Kater"},{"full_name":"Hietter-Pfeiffer, Eric","first_name":"Eric","last_name":"Hietter-Pfeiffer"},{"first_name":"Mina","full_name":"Haddawi, Mina","last_name":"Haddawi"},{"full_name":"Kuber, Urja P.","first_name":"Urja P.","last_name":"Kuber"},{"full_name":"Mühlhäusser, Sandra","first_name":"Sandra","last_name":"Mühlhäusser"},{"last_name":"Grand","first_name":"Ralph S.","full_name":"Grand, Ralph S."},{"first_name":"Michael B.","full_name":"Stadler, Michael B.","last_name":"Stadler"},{"full_name":"Deindl, Sebastian","first_name":"Sebastian","last_name":"Deindl"},{"last_name":"Thomä","full_name":"Thomä, Nicolas H.","first_name":"Nicolas H."}],"type":"journal_article","intvolume":"        86","article_type":"original","doi":"10.1016/j.molcel.2026.01.021","oa_version":"Published Version","ddc":["570"],"PlanS_conform":"1","abstract":[{"text":"Chromatin remodeling complexes mobilize nucleosomes and promote transcription factor (TF) binding. Using ensemble and single-molecule assays combined with cryo-electron microscopy (cryo-EM), we studied the interaction between pioneer TFs OCT4–SOX2 and the human BRG1/BRM-associated factor (BAF) complex on nucleosomes. BAF engages TF-bound substrates in two orientations, placing OCT4–SOX2 at either the remodeler ENTRY or EXIT site. At the ENTRY site, OCT4–SOX2 initially coexists with BAF without structural interference. However, continued DNA translocation is expected to cause collisions with bound TFs, which can trigger remodeling direction reversals or may induce TF dissociation. To accommodate TFs at the EXIT site, BAF undergoes structural rearrangements, and ensemble assays reveal a nucleosome subpopulation translocating away from TF-binding sites. Moreover, single-molecule experiments show that nucleosome-bound BAF frequently changes remodeling direction, and we identify an ADP-bound remodeler conformation as a potential intermediate. Together, these findings reveal key aspects of the conformational dynamics and remodeling outcomes underlying BAF processing of TF-bound nucleosomes.","lang":"eng"}],"department":[{"_id":"AlMi"}],"title":"The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4–SOX2","OA_type":"hybrid","quality_controlled":"1","publisher":"Elsevier","month":"02","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"year":"2026","publication":"Molecular Cell","_id":"21509","citation":{"ieee":"J. Weiss <i>et al.</i>, “The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4–SOX2,” <i>Molecular Cell</i>, vol. 86, no. 4. Elsevier, p. 625–639.e8, 2026.","chicago":"Weiss, Joscha, Luca Vecchia, David Domjan, Simone Cavadini, Anton Sabantsev, Georg Kempf, Ganesh R. Pathare, et al. “The Human BAF Chromatin Remodeler Processes Nucleosomes Bound by Pioneer Transcription Factors OCT4–SOX2.” <i>Molecular Cell</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.molcel.2026.01.021\">https://doi.org/10.1016/j.molcel.2026.01.021</a>.","mla":"Weiss, Joscha, et al. “The Human BAF Chromatin Remodeler Processes Nucleosomes Bound by Pioneer Transcription Factors OCT4–SOX2.” <i>Molecular Cell</i>, vol. 86, no. 4, Elsevier, 2026, p. 625–639.e8, doi:<a href=\"https://doi.org/10.1016/j.molcel.2026.01.021\">10.1016/j.molcel.2026.01.021</a>.","ista":"Weiss J, Vecchia L, Domjan D, Cavadini S, Sabantsev A, Kempf G, Pathare GR, Brackmann K, Michael AK, Kater L, Hietter-Pfeiffer E, Haddawi M, Kuber UP, Mühlhäusser S, Grand RS, Stadler MB, Deindl S, Thomä NH. 2026. The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4–SOX2. Molecular Cell. 86(4), 625–639.e8.","ama":"Weiss J, Vecchia L, Domjan D, et al. The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4–SOX2. <i>Molecular Cell</i>. 2026;86(4):625-639.e8. doi:<a href=\"https://doi.org/10.1016/j.molcel.2026.01.021\">10.1016/j.molcel.2026.01.021</a>","short":"J. Weiss, L. Vecchia, D. Domjan, S. Cavadini, A. Sabantsev, G. Kempf, G.R. Pathare, K. Brackmann, A.K. Michael, L. Kater, E. Hietter-Pfeiffer, M. Haddawi, U.P. Kuber, S. Mühlhäusser, R.S. Grand, M.B. Stadler, S. Deindl, N.H. Thomä, Molecular Cell 86 (2026) 625–639.e8.","apa":"Weiss, J., Vecchia, L., Domjan, D., Cavadini, S., Sabantsev, A., Kempf, G., … Thomä, N. H. (2026). The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4–SOX2. <i>Molecular Cell</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.molcel.2026.01.021\">https://doi.org/10.1016/j.molcel.2026.01.021</a>"},"article_processing_charge":"Yes (in subscription journal)","volume":86,"acknowledgement":"We thank D. Hess, V. Iesmantavicius, and J. Seebacher (FMI Proteomics and Protein Analysis Facility) for mass spectrometry support; S. Smallwood, K. Shimada, D. Klein, and M. Schütz-Stoffregen for technical assistance; J. Côté and C. Lachance for critical discussions; and members of the Thomä lab for helpful feedback. Support for this work was provided to N.H.T. by the European Research Council under the European Union’s Horizon 2020 research program (NucEM, no. 884331), the Novartis Research Foundation, the Swiss National Science Foundation (SNF 31003A_179541, 310030_214852, and Sinergia CRSII5_186230), and the Swiss Cancer Research (KFS-4980-02-2020 and KFS-5933-08-2023). S.D. was supported by the European Research Council (DONUTS, no. 101092623), the Knut and Alice Wallenberg Foundation (2024.0012), the Cancerfonden (25 4453 Pj), and the Swedish Research Council (VR 03255). A.K.M. was supported by a Human Frontier Science Program Long-Term Fellowship, and L.V. was supported by an EMBO fellowship (ALTF 549-2021).","file_date_updated":"2026-03-30T12:04:38Z","external_id":{"pmid":["41679301"]},"oa":1,"has_accepted_license":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"file_size":9786677,"file_name":"2026_MolecularCell_Weiss.pdf","creator":"dernst","file_id":"21510","date_updated":"2026-03-30T12:04:38Z","content_type":"application/pdf","access_level":"open_access","relation":"main_file","checksum":"e16a7315b64a706184b177ea1621523c","success":1,"date_created":"2026-03-30T12:04:38Z"}],"scopus_import":"1","fulldoi":"https://doi.org/10.1016/j.molcel.2026.01.021","language":[{"iso":"eng"}],"date_published":"2026-02-19T00:00:00Z","pmid":1,"date_updated":"2026-03-30T12:09:08Z","publication_status":"published","status":"public","publication_identifier":{"issn":["1097-2765"]},"issue":"4"},{"OA_place":"publisher","author":[{"last_name":"Baig","first_name":"Mirza Ahad","full_name":"Baig, Mirza Ahad","id":"3EDE6DE4-AA5A-11E9-986D-341CE6697425"}],"type":"dissertation","date_created":"2026-04-02T09:31:34Z","corr_author":"1","day":"04","related_material":{"record":[{"relation":"part_of_dissertation","id":"21134","status":"public"},{"relation":"part_of_dissertation","status":"public","id":"20587"}]},"supervisor":[{"id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87","full_name":"Pietrzak, Krzysztof Z","first_name":"Krzysztof Z","orcid":"0000-0002-9139-1654","last_name":"Pietrzak"}],"alternative_title":["ISTA Thesis"],"abstract":[{"lang":"eng","text":"Blockchains enable distributed consensus in permissionless settings, where participants\r\nare unknown, dynamically changing, and do not trust each other. While Bitcoin,\r\nbased on Proof-of-Work (PoW), was the first protocol in this model, significant\r\nresearch has focused on permissionless protocols using alternative physical resources,\r\nspecifically Proof-of-Space (PoSpace) and Verifiable Delay Functions (VDFs). This\r\nthesis investigates the theoretical limits and design space of longest-chain protocols in\r\nthe fully permissionless and dynamically available settings using these three resources.\r\nFirst, we address the feasibility of blockchains relying solely on storage as a resource.\r\nWe prove a fundamental impossibility result: there exists no secure longest-chain\r\nprotocol based exclusively on Proof-of-Space in the fully permissionless or dynamically\r\navailable settings. Further, we quantify the adversarial capabilities required to execute\r\na double-spend attack. Our result formally justifies the necessity of coupling PoSpace\r\nwith time-dependent primitives (such as VDFs) or to move to less permissive settings\r\n(quasi-permissionless or permissioned) to ensure security.\r\nSecond, we generalize Nakamoto-like heaviest chain consensus to protocols utilizing\r\ncombinations of multiple physical resources. We analyze chain selection rules governed\r\nby a weight function Γ(S, V,W), which assigns weight to blocks based on recorded\r\nSpace (S), VDF speed (V ), and Work (W). We provide a complete classification\r\nof secure weight functions, proving that a weight function is secure against private\r\ndouble-spend attacks if and only if it is homogeneous in the timed resources (V,W)\r\nand sub-homogeneous in S. This framework unifies existing protocols like Bitcoin and\r\nChia under a single theoretical model and provides a powerful tool for designing new\r\nlongest-chain blockchains from a mix of physical resources."}],"degree_awarded":"PhD","department":[{"_id":"GradSch"},{"_id":"KrPi"}],"title":"On secure chain selection rules from physical resources in a permissionless setting","ddc":["000"],"oa_version":"Published Version","doi":"10.15479/AT-ISTA-21651","file":[{"relation":"source_file","checksum":"c3986dba90653dac97adba662ebff238","date_created":"2026-04-03T17:28:48Z","file_size":139353434,"file_name":"PhD-Thesis-Mirza-Ahad-Baig - Library Submission.zip","creator":"mbaig","date_updated":"2026-04-13T08:24:13Z","file_id":"21655","content_type":"application/x-zip-compressed","access_level":"closed"},{"creator":"mbaig","file_size":1942037,"file_name":"2026_Baig_Mirza_Ahad_Thesis.pdf","file_id":"21656","date_updated":"2026-04-15T07:37:25Z","content_type":"application/pdf","access_level":"open_access","relation":"main_file","checksum":"292a5989262521f7c145a109d1f348cb","date_created":"2026-04-03T17:29:30Z"}],"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","language":[{"iso":"eng"}],"fulldoi":"https://doi.org/10.15479/AT-ISTA-21651","date_published":"2026-03-04T00:00:00Z","article_processing_charge":"No","citation":{"ieee":"M. A. Baig, “On secure chain selection rules from physical resources in a permissionless setting,” Institute of Science and Technology Austria, 2026.","chicago":"Baig, Mirza Ahad. “On Secure Chain Selection Rules from Physical Resources in a Permissionless Setting.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21651\">https://doi.org/10.15479/AT-ISTA-21651</a>.","mla":"Baig, Mirza Ahad. <i>On Secure Chain Selection Rules from Physical Resources in a Permissionless Setting</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21651\">10.15479/AT-ISTA-21651</a>.","ama":"Baig MA. On secure chain selection rules from physical resources in a permissionless setting. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21651\">10.15479/AT-ISTA-21651</a>","ista":"Baig MA. 2026. On secure chain selection rules from physical resources in a permissionless setting. Institute of Science and Technology Austria.","short":"M.A. Baig, On Secure Chain Selection Rules from Physical Resources in a Permissionless Setting, Institute of Science and Technology Austria, 2026.","apa":"Baig, M. A. (2026). <i>On secure chain selection rules from physical resources in a permissionless setting</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21651\">https://doi.org/10.15479/AT-ISTA-21651</a>"},"has_accepted_license":"1","oa":1,"file_date_updated":"2026-04-15T07:37:25Z","_id":"21651","month":"03","publisher":"Institute of Science and Technology Austria","tmp":{"name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)","image":"/images/cc_by_nc_sa.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","short":"CC BY-NC-SA (4.0)"},"year":"2026","publication_identifier":{"issn":["2663-337X"],"isbn":["978-3-99078-078-7"]},"publication_status":"published","status":"public","date_updated":"2026-04-15T08:45:19Z"},{"ddc":["550"],"oa_version":"Published Version","doi":"10.1029/2025MS005343","article_type":"original","OA_type":"gold","quality_controlled":"1","department":[{"_id":"CaMu"}],"title":"Precipitation characteristics and thermodynamic-convection coupling in global kilometer-scale simulations","abstract":[{"lang":"eng","text":"We compare three global kilometer-scale models (ICON, IFS and NICAM) to clarify the advantages and challenges of high-resolution global weather and climate modeling, using different approaches to represent convection, from fully parameterized to fully explicit. Our analysis focuses on tropical precipitation characteristics spanning a wide range of spatio-temporal scales—including the diurnal cycle, extreme precipitation, convective organization, and the Madden-Julian Oscillation (MJO)—along with interactions between convection and the thermodynamic environment. All three models commonly show weaker convective organization with smaller precipitation cells than observed, though the strength of the bias varies by model. This diversity is introduced by differences in the representation of (a) convective initiation affected by the convective sensitivity to moisture and (b) tropospheric moistening associated with deep convection. Models with stronger thermodynamic-convection coupling increase environmental moisture near convection, thereby enhancing convective organization. This has important upscale effects on the MJO; while IFS and NICAM capture its eastward propagation well, ICON has difficulty reproducing it. The amplitudes and phases of precipitation diurnal cycles over land show much greater disagreement among the models than over ocean, influenced by how convection is initiated. Biases in rain evaporation and cold pool formation hinder the propagation of mesoscale convection, leading to errors such as the misrepresentation of nocturnal convection moving off the coast of Sumatra in IFS and ICON. These results highlight the importance of thermodynamic-convection coupling in realistically simulating tropical convection across scales. To improve this coupling, kilometer-scale models require better representation of the interaction between resolved convection and three-dimensional turbulent mixing."}],"DOAJ_listed":"1","day":"01","corr_author":"1","intvolume":"        18","type":"journal_article","project":[{"call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"OA_place":"publisher","author":[{"last_name":"Takasuka","first_name":"Daisuke","full_name":"Takasuka, Daisuke"},{"last_name":"Becker","first_name":"Tobias","full_name":"Becker, Tobias"},{"first_name":"Jiawei","full_name":"Bao, Jiawei","id":"bb9a7399-fefd-11ed-be3c-ae648fd1d160","last_name":"Bao"}],"date_created":"2026-04-05T22:01:31Z","date_updated":"2026-06-16T10:43:35Z","ec_funded":1,"issue":"3","publication_identifier":{"eissn":["1942-2466"]},"status":"public","article_number":"e2025MS005343","publication_status":"published","_id":"21657","publication":"Journal of Advances in Modeling Earth Systems","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"year":"2026","month":"03","publisher":"Wiley","scopus_import":"1","fulldoi":"https://doi.org/10.1029/2025MS005343","language":[{"iso":"eng"}],"date_published":"2026-03-01T00:00:00Z","file":[{"date_created":"2026-04-07T09:11:23Z","relation":"main_file","success":1,"checksum":"ca7dac4bab31348d0640ed22580c6dce","content_type":"application/pdf","access_level":"open_access","creator":"dernst","file_name":"2026_JAMES_Takasuka.pdf","file_size":3854313,"date_updated":"2026-04-07T09:11:23Z","file_id":"21665"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","has_accepted_license":"1","oa":1,"file_date_updated":"2026-04-07T09:11:23Z","acknowledgement":"We thank Peter Bechtold, Lukas Brunner, Peter Dueben, Richard Forbes, Estibaliz Gascon, and Benoit Vanniere for providing insightful comments on the present study. We also thank Sebastian Milinski, Xabier Pedruzo and Thomas Rackow for their contributions to setting up IFS-FESOM for nextGEMS. We are also grateful to Dr. Walter Hannah and an anonymous reviewer for their constructive comments, which improved the original version of the manuscript. D. Takasuka was supported by JSPS KAKENHI Grants 20H05728 and 24K22893 and by JSPS Core-to-Core Program, “International Core-to-Core Project on Global Storm Resolving Analysis” (Grant Number: JPJSCCA20220001). T. Becker was supported by the Horizon 2020 project nextGEMS under grant agreement number 101003470. J. Bao acknowledges funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant (grant agreement No 101034413). The ICON and IFS simulations were performed with supercomputing resources of the German Climate Computing Centre (Deutsches Klimarechenzentrum, DKRZ) granted by its Scientific Steering Committee (WLA) under project ID 1235. The NICAM simulation was performed on the supercomputer Fugaku (proposal numbers hp220132, hp230078, hp230108, hp230278, and hp240267).","volume":18,"citation":{"ieee":"D. Takasuka, T. Becker, and J. Bao, “Precipitation characteristics and thermodynamic-convection coupling in global kilometer-scale simulations,” <i>Journal of Advances in Modeling Earth Systems</i>, vol. 18, no. 3. Wiley, 2026.","chicago":"Takasuka, Daisuke, Tobias Becker, and Jiawei Bao. “Precipitation Characteristics and Thermodynamic-Convection Coupling in Global Kilometer-Scale Simulations.” <i>Journal of Advances in Modeling Earth Systems</i>. Wiley, 2026. <a href=\"https://doi.org/10.1029/2025MS005343\">https://doi.org/10.1029/2025MS005343</a>.","mla":"Takasuka, Daisuke, et al. “Precipitation Characteristics and Thermodynamic-Convection Coupling in Global Kilometer-Scale Simulations.” <i>Journal of Advances in Modeling Earth Systems</i>, vol. 18, no. 3, e2025MS005343, Wiley, 2026, doi:<a href=\"https://doi.org/10.1029/2025MS005343\">10.1029/2025MS005343</a>.","ista":"Takasuka D, Becker T, Bao J. 2026. Precipitation characteristics and thermodynamic-convection coupling in global kilometer-scale simulations. Journal of Advances in Modeling Earth Systems. 18(3), e2025MS005343.","ama":"Takasuka D, Becker T, Bao J. Precipitation characteristics and thermodynamic-convection coupling in global kilometer-scale simulations. <i>Journal of Advances in Modeling Earth Systems</i>. 2026;18(3). doi:<a href=\"https://doi.org/10.1029/2025MS005343\">10.1029/2025MS005343</a>","short":"D. Takasuka, T. Becker, J. Bao, Journal of Advances in Modeling Earth Systems 18 (2026).","apa":"Takasuka, D., Becker, T., &#38; Bao, J. (2026). Precipitation characteristics and thermodynamic-convection coupling in global kilometer-scale simulations. <i>Journal of Advances in Modeling Earth Systems</i>. Wiley. <a href=\"https://doi.org/10.1029/2025MS005343\">https://doi.org/10.1029/2025MS005343</a>"},"article_processing_charge":"Yes"},{"quality_controlled":"1","OA_type":"gold","abstract":[{"lang":"eng","text":"Kapitza-Dirac scattering, the diffraction of matter waves from a standing light field, is widely utilized in ultracold gases, but its behavior in the strongly interacting regime is an open question. Here, we develop a numerically exact two-body description of Kapitza-Dirac scattering for two contact-interacting atoms in a one-dimensional harmonic trap subjected to a pulsed optical lattice, enabling us to obtain the numerically exact dynamics. We map how interaction strength, lattice depth, lattice wave number, and pulse duration reshape the diffraction pattern, leading to an interaction-dependent population redistribution in real and momentum space. By comparing the exact dynamics to an impulsive sudden-approximation description, we delineate the parameter regimes where it remains accurate and those, notably at strong attraction and small lattice wave number, where it fails. Our results provide a controlled few-body benchmark for interacting Kapitza-Dirac scattering and quantitative guidance for Kapitza-Dirac-based probes of ultracold atomic systems."}],"DOAJ_listed":"1","department":[{"_id":"MiLe"}],"title":"Two-body Kapitza-Dirac scattering of one-dimensional ultracold atoms","ddc":["530"],"PlanS_conform":"1","oa_version":"Published Version","article_type":"original","doi":"10.1103/rdsn-stlq","author":[{"first_name":"A.","full_name":"Becker, A.","last_name":"Becker"},{"last_name":"Koutentakis","full_name":"Koutentakis, Georgios","id":"d7b23d3a-9e21-11ec-b482-f76739596b95","first_name":"Georgios"},{"last_name":"Schmelcher","full_name":"Schmelcher, P.","first_name":"P."}],"OA_place":"publisher","project":[{"name":"Coherent Optical Metrology Beyond Electric-Dipole-Allowed Transitions","_id":"7c040762-9f16-11ee-852c-dd79eeee4ab3","grant_number":"F100403"}],"type":"journal_article","intvolume":"         8","date_created":"2026-04-05T22:01:32Z","corr_author":"1","day":"18","publication_identifier":{"issn":["2643-1564"]},"publication_status":"published","article_number":"013297","status":"public","date_updated":"2026-04-07T09:37:57Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"date_created":"2026-04-07T09:34:31Z","checksum":"339bff9d13486a8028049404988b9b0b","success":1,"relation":"main_file","access_level":"open_access","content_type":"application/pdf","date_updated":"2026-04-07T09:34:31Z","file_id":"21667","creator":"dernst","file_size":2131627,"file_name":"2026_PhysicalReviewResearch_Becker.pdf"}],"fulldoi":"https://doi.org/10.1103/rdsn-stlq","scopus_import":"1","date_published":"2026-03-18T00:00:00Z","language":[{"iso":"eng"}],"article_processing_charge":"Yes","volume":8,"citation":{"ama":"Becker A, Koutentakis G, Schmelcher P. Two-body Kapitza-Dirac scattering of one-dimensional ultracold atoms. <i>Physical Review Research</i>. 2026;8. doi:<a href=\"https://doi.org/10.1103/rdsn-stlq\">10.1103/rdsn-stlq</a>","ista":"Becker A, Koutentakis G, Schmelcher P. 2026. Two-body Kapitza-Dirac scattering of one-dimensional ultracold atoms. Physical Review Research. 8, 013297.","apa":"Becker, A., Koutentakis, G., &#38; Schmelcher, P. (2026). Two-body Kapitza-Dirac scattering of one-dimensional ultracold atoms. <i>Physical Review Research</i>. American Physical Society. <a href=\"https://doi.org/10.1103/rdsn-stlq\">https://doi.org/10.1103/rdsn-stlq</a>","short":"A. Becker, G. Koutentakis, P. Schmelcher, Physical Review Research 8 (2026).","ieee":"A. Becker, G. Koutentakis, and P. Schmelcher, “Two-body Kapitza-Dirac scattering of one-dimensional ultracold atoms,” <i>Physical Review Research</i>, vol. 8. American Physical Society, 2026.","mla":"Becker, A., et al. “Two-Body Kapitza-Dirac Scattering of One-Dimensional Ultracold Atoms.” <i>Physical Review Research</i>, vol. 8, 013297, American Physical Society, 2026, doi:<a href=\"https://doi.org/10.1103/rdsn-stlq\">10.1103/rdsn-stlq</a>.","chicago":"Becker, A., Georgios Koutentakis, and P. Schmelcher. “Two-Body Kapitza-Dirac Scattering of One-Dimensional Ultracold Atoms.” <i>Physical Review Research</i>. American Physical Society, 2026. <a href=\"https://doi.org/10.1103/rdsn-stlq\">https://doi.org/10.1103/rdsn-stlq</a>."},"acknowledgement":"We thank Max Hachmann, Andreas Hemmerich, and Yann Kiefer for valuable discussions. This work has been funded by the Cluster of Excellence “Advanced Imaging of Matter” of the Deutsche Forschungsgemeinschaft (DFG) - EXC 2056 - Project ID 390715994. G.M.K. has received funding by the Austrian Science Fund (FWF) 10.55776/F1004.","file_date_updated":"2026-04-07T09:34:31Z","external_id":{"arxiv":["2512.15260"]},"oa":1,"has_accepted_license":"1","arxiv":1,"publication":"Physical Review Research","_id":"21660","publisher":"American Physical Society","month":"03","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"year":"2026"},{"status":"public","publication_status":"epub_ahead","keyword":["Quantitative model checking","Markov decision process","Linear programming","Value iteration","Policy iteration"],"publication_identifier":{"issn":["1433-2779"],"eissn":["1433-2787"]},"ec_funded":1,"date_updated":"2026-04-07T09:52:54Z","oa":1,"has_accepted_license":"1","citation":{"ista":"Hartmanns A, Junges S, Quatmann T, Weininger M. 2026. The revised practitioner’s guide to MDP model checking algorithms. International Journal on Software Tools for Technology Transfer.","ama":"Hartmanns A, Junges S, Quatmann T, Weininger M. The revised practitioner’s guide to MDP model checking algorithms. <i>International Journal on Software Tools for Technology Transfer</i>. 2026. doi:<a href=\"https://doi.org/10.1007/s10009-026-00848-y\">10.1007/s10009-026-00848-y</a>","short":"A. Hartmanns, S. Junges, T. Quatmann, M. Weininger, International Journal on Software Tools for Technology Transfer (2026).","apa":"Hartmanns, A., Junges, S., Quatmann, T., &#38; Weininger, M. (2026). The revised practitioner’s guide to MDP model checking algorithms. <i>International Journal on Software Tools for Technology Transfer</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s10009-026-00848-y\">https://doi.org/10.1007/s10009-026-00848-y</a>","ieee":"A. Hartmanns, S. Junges, T. Quatmann, and M. Weininger, “The revised practitioner’s guide to MDP model checking algorithms,” <i>International Journal on Software Tools for Technology Transfer</i>. Springer Nature, 2026.","chicago":"Hartmanns, Arnd, Sebastian Junges, Tim Quatmann, and Maximilian Weininger. “The Revised Practitioner’s Guide to MDP Model Checking Algorithms.” <i>International Journal on Software Tools for Technology Transfer</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1007/s10009-026-00848-y\">https://doi.org/10.1007/s10009-026-00848-y</a>.","mla":"Hartmanns, Arnd, et al. “The Revised Practitioner’s Guide to MDP Model Checking Algorithms.” <i>International Journal on Software Tools for Technology Transfer</i>, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1007/s10009-026-00848-y\">10.1007/s10009-026-00848-y</a>."},"article_processing_charge":"Yes (in subscription journal)","acknowledgement":"This research was funded by the European Union’s Horizon 2020 research and innovation programme under Marie Skłodowska-Curie grant agreements 101008233 (MISSION)\r\nand 101034413 (IST-BRIDGE), by the Interreg North Sea project STORM_SAFE, by a KI-Starter grant from the Ministerium für Kultur und Wissenschaft NRW, by NWO VENI grant no. 639.021.754, and by NWO VIDI grant VI.Vidi.223.110 (TruSTy). Experiments were performed with computing resources granted by RWTH Aachen University under project rwth1632.","fulldoi":"https://doi.org/10.1007/s10009-026-00848-y","scopus_import":"1","date_published":"2026-03-09T00:00:00Z","language":[{"iso":"eng"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2026","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"publisher":"Springer Nature","month":"03","_id":"21661","publication":"International Journal on Software Tools for Technology Transfer","title":"The revised practitioner’s guide to MDP model checking algorithms","department":[{"_id":"KrCh"}],"abstract":[{"text":"Model checking undiscounted reachability and expected-reward properties on Markov decision processes (MDPs) are key for the verification of systems that act under uncertainty. Popular algorithms are policy iteration and variants of value iteration; in tool competitions, most participants rely on the latter. These algorithms generally need worst-case exponential time. However, the problem can equally be formulated as a linear programme, solvable in polynomial time. In this paper, we give a detailed overview of today’s state-of-the-art algorithms for MDP model checking with a focus on performance and correctness. We highlight their fundamental differences, and describe various optimizations and implementation variants. We experimentally compare floating-point and exact-arithmetic implementations of all algorithms on three benchmark sets using two probabilistic model checkers. Our results show that (optimistic) value iteration is a sensible default, but other algorithms are preferable in specific settings. This paper thereby provides a guide for MDP verification practitioners—tool builders and users alike.","lang":"eng"}],"quality_controlled":"1","OA_type":"hybrid","doi":"10.1007/s10009-026-00848-y","article_type":"original","oa_version":"Published Version","ddc":["000"],"date_created":"2026-04-05T22:01:32Z","type":"journal_article","OA_place":"publisher","author":[{"first_name":"Arnd","full_name":"Hartmanns, Arnd","last_name":"Hartmanns"},{"last_name":"Junges","first_name":"Sebastian","full_name":"Junges, Sebastian"},{"last_name":"Quatmann","first_name":"Tim","full_name":"Quatmann, Tim"},{"orcid":"0000-0002-0163-2152","last_name":"Weininger","first_name":"Maximilian","id":"02ab0197-cc70-11ed-ab61-918e71f56881","full_name":"Weininger, Maximilian"}],"project":[{"name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","call_identifier":"H2020"}],"main_file_link":[{"url":"https://doi.org/10.1007/s10009-026-00848-y","open_access":"1"}],"related_material":{"record":[{"relation":"software","status":"public","id":"21668"}]},"day":"09"},{"doi":"10.48550/arXiv.2604.07653","date_updated":"2026-05-04T06:27:12Z","oa_version":"Preprint","abstract":[{"text":"Altermagnetism has recently emerged as a distinct class of collinear antiferromagnets that break time-reversal symmetry, exhibiting a host of novel properties. Applied strain has attracted particular attention as a key tuning parameter for altermagnets. Although several experimental studies have demonstrated the preparation of single-domain states through a combination of applied strain and magnetic field, the route to such states remains unclear. Here, we use magneto-optical measurements on single crystals of MnTe under applied strain to show that, in contrast to previous reports, strain acts primarily to rotate the Néel vector L continuously. Since the orientation of L determines the magnetic point group symmetry, this continuous rotation effectively tunes the symmetry and its associated physical properties. Furthermore, we demonstrate that built-in strain in free-standing crystals is sufficient to pin L into continuous textures over millimeter length scales. Together, these results provide guidance for future device design and open the door to leveraging the Néel vector orientation as a tunable degree of freedom in spintronic applications.","lang":"eng"}],"article_number":"2604.07653","publication_status":"submitted","title":"Strain continuously rotates the Néel vector in altermagnetic MnTe","department":[{"_id":"VeSu"}],"status":"public","OA_type":"green","month":"04","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2604.07653","open_access":"1"}],"year":"2026","publication":"arXiv","_id":"21703","day":"08","acknowledgement":"This research was primarily funded by the Quantum Materials (KC2202) program under the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences, Materials Sciences and Engineering Division under Contract No. DE-AC02-05CH11231, which supported the experimental and theoretical work at the LBNL and UC Berkeley. N.J.G., R. B. R., and I.I.M.\r\nwere supported by Army Research Office under Cooperative Agreement Number W911NF- 22-2-0173. H.M.L.N. and V.S. acknowledge funding through the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) through Grant No. TRR288—422213477, Project No. A10. H.M.L.N. acknowledges financial support from the Max Planck Society. Research in Dresden benefits from the environment provided by the DFG Cluster of Excellence ctd.qmat (EXC2147, Project ID 390858490).","citation":{"ista":"Alex Liebman-Peláez AL-P, Kruppe J, Regmi RB, Ghimire NJ, Sun Y, Mazin II, Noad HML, Analytis J, Sunko V, Orenstein J. Strain continuously rotates the Néel vector in altermagnetic MnTe. arXiv, 2604.07653.","ama":"Alex Liebman-Peláez AL-P, Kruppe J, Regmi RB, et al. Strain continuously rotates the Néel vector in altermagnetic MnTe. <i>arXiv</i>. doi:<a href=\"https://doi.org/10.48550/arXiv.2604.07653\">10.48550/arXiv.2604.07653</a>","short":"A.L.-P. Alex Liebman-Peláez, J. Kruppe, R.B. Regmi, N.J. Ghimire, Y. Sun, I.I. Mazin, H.M.L. Noad, J. Analytis, V. Sunko, J. Orenstein, ArXiv (n.d.).","apa":"Alex Liebman-Peláez, A. L.-P., Kruppe, J., Regmi, R. B., Ghimire, N. J., Sun, Y., Mazin, I. I., … Orenstein, J. (n.d.). Strain continuously rotates the Néel vector in altermagnetic MnTe. <i>arXiv</i>. <a href=\"https://doi.org/10.48550/arXiv.2604.07653\">https://doi.org/10.48550/arXiv.2604.07653</a>","ieee":"A. L.-P. Alex Liebman-Peláez <i>et al.</i>, “Strain continuously rotates the Néel vector in altermagnetic MnTe,” <i>arXiv</i>. .","chicago":"Alex Liebman-Peláez, Alex Liebman-Peláez, Jon Kruppe, Resham Babu Regmi, Nirmal J. Ghimire, Yue Sun, Igor I. Mazin, Hilary M. L. Noad, James Analytis, Veronika Sunko, and Joseph Orenstein. “Strain Continuously Rotates the Néel Vector in Altermagnetic MnTe.” <i>ArXiv</i>, n.d. <a href=\"https://doi.org/10.48550/arXiv.2604.07653\">https://doi.org/10.48550/arXiv.2604.07653</a>.","mla":"Alex Liebman-Peláez, Alex Liebman-Peláez, et al. “Strain Continuously Rotates the Néel Vector in Altermagnetic MnTe.” <i>ArXiv</i>, 2604.07653, doi:<a href=\"https://doi.org/10.48550/arXiv.2604.07653\">10.48550/arXiv.2604.07653</a>."},"article_processing_charge":"No","oa":1,"date_created":"2026-04-10T14:17:21Z","arxiv":1,"external_id":{"arxiv":["2604.07653"]},"OA_place":"repository","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"full_name":"Alex Liebman-Peláez, Alex Liebman-Peláez","first_name":"Alex Liebman-Peláez","last_name":"Alex Liebman-Peláez"},{"last_name":"Kruppe","full_name":"Kruppe, Jon","first_name":"Jon"},{"full_name":"Regmi, Resham Babu","first_name":"Resham Babu","last_name":"Regmi"},{"last_name":"Ghimire","first_name":"Nirmal J.","full_name":"Ghimire, Nirmal J."},{"last_name":"Sun","first_name":"Yue","full_name":"Sun, Yue"},{"full_name":"Mazin, Igor I.","first_name":"Igor I.","last_name":"Mazin"},{"last_name":"Noad","first_name":"Hilary M. L.","full_name":"Noad, Hilary M. L."},{"full_name":"Analytis, James","first_name":"James","last_name":"Analytis"},{"first_name":"Veronika","id":"23cb1cf6-2c7a-11ef-91a4-f72fc19f20b3","full_name":"Sunko, Veronika","last_name":"Sunko","orcid":"0000-0003-2724-3523"},{"last_name":"Orenstein","first_name":"Joseph","full_name":"Orenstein, Joseph"}],"type":"preprint","fulldoi":"https://doi.org/10.48550/arXiv.2604.07653","date_published":"2026-04-08T00:00:00Z","language":[{"iso":"eng"}]},{"author":[{"last_name":"Isakova","full_name":"Isakova, Lada H.","first_name":"Lada H."},{"full_name":"Streltsova, Elizaveta","id":"57a170da-dc96-11ea-b7c8-ab3565071bf7","first_name":"Elizaveta","last_name":"Streltsova"},{"last_name":"Bochkareva","orcid":"0000-0003-1006-6639","first_name":"Olga","id":"C4558D3C-6102-11E9-A62E-F418E6697425","full_name":"Bochkareva, Olga"},{"last_name":"Vlasov","first_name":"Peter K.","full_name":"Vlasov, Peter K."},{"last_name":"Kondrashov","orcid":"0000-0001-8243-4694","full_name":"Kondrashov, Fyodor","id":"44FDEF62-F248-11E8-B48F-1D18A9856A87","first_name":"Fyodor"}],"OA_place":"publisher","type":"journal_article","intvolume":"       123","date_created":"2026-04-12T22:01:47Z","day":"07","page":"e2532018123","quality_controlled":"1","OA_type":"hybrid","abstract":[{"text":"How functional protein sequences are distributed in sequence space is fundamentally important for evolutionary theory and protein design, particularly if a large diversity of protein functions are hidden in evolutionarily unexplored areas of the sequence space. However, this question is understudied in part because experimental and computational studies use extant sequences as a starting point to study sequence space. Here, we study whether extant sequences are representative of the entire functional sequence space. Across thousands of protein families from vertebrates and bacteria we calculate the dimensionality and the volume of sequence space occupied by extant homologs. We find that the observed dimensionality and volume of extant sequence space are minuscule, many orders of magnitude smaller than what we estimated using a model of protein evolution. Simulating sequence evolution we then quantify the impact of phylogeny, selection, and epistasis on restricting the evolutionary exploration of sequence space. We find that sequence evolution from a single common ancestor, or a single point of origin in sequence space, is by far the largest limiting factor that reduces the dimensionality and volume of extant sequence space. These results indicate that there are vast areas of functional sequence space that have not been explored in evolution because of the excessive restrictions on natural exploration of the protein sequence space imposed by the point of origin effect. We suggest that protein design methods that rely on extant sequences may be limited in their ability to discover truly novel functions.","lang":"eng"}],"department":[{"_id":"UlWa"}],"title":"Descent from a common ancestor restricts exploration of protein sequence space","oa_version":"Published Version","ddc":["570"],"doi":"10.1073/pnas.2532018123","article_type":"original","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"relation":"main_file","checksum":"11b7a13a359e302498b2367906093a6b","success":1,"date_created":"2026-05-04T06:46:31Z","creator":"dernst","file_name":"2026_PNAS_Isakova.pdf","file_size":3355016,"date_updated":"2026-05-04T06:46:31Z","file_id":"21783","content_type":"application/pdf","access_level":"open_access"}],"date_published":"2026-04-07T00:00:00Z","fulldoi":"https://doi.org/10.1073/pnas.2532018123","language":[{"iso":"eng"}],"scopus_import":"1","article_processing_charge":"Yes (in subscription journal)","citation":{"ama":"Isakova LH, Streltsova E, Bochkareva O, Vlasov PK, Kondrashov F. Descent from a common ancestor restricts exploration of protein sequence space. <i>Proceedings of the National Academy of Sciences</i>. 2026;123(14):e2532018123. doi:<a href=\"https://doi.org/10.1073/pnas.2532018123\">10.1073/pnas.2532018123</a>","ista":"Isakova LH, Streltsova E, Bochkareva O, Vlasov PK, Kondrashov F. 2026. Descent from a common ancestor restricts exploration of protein sequence space. Proceedings of the National Academy of Sciences. 123(14), e2532018123.","short":"L.H. Isakova, E. Streltsova, O. Bochkareva, P.K. Vlasov, F. Kondrashov, Proceedings of the National Academy of Sciences 123 (2026) e2532018123.","apa":"Isakova, L. H., Streltsova, E., Bochkareva, O., Vlasov, P. K., &#38; Kondrashov, F. (2026). Descent from a common ancestor restricts exploration of protein sequence space. <i>Proceedings of the National Academy of Sciences</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.2532018123\">https://doi.org/10.1073/pnas.2532018123</a>","ieee":"L. H. Isakova, E. Streltsova, O. Bochkareva, P. K. Vlasov, and F. Kondrashov, “Descent from a common ancestor restricts exploration of protein sequence space,” <i>Proceedings of the National Academy of Sciences</i>, vol. 123, no. 14. National Academy of Sciences, p. e2532018123, 2026.","chicago":"Isakova, Lada H., Elizaveta Streltsova, Olga Bochkareva, Peter K. Vlasov, and Fyodor Kondrashov. “Descent from a Common Ancestor Restricts Exploration of Protein Sequence Space.” <i>Proceedings of the National Academy of Sciences</i>. National Academy of Sciences, 2026. <a href=\"https://doi.org/10.1073/pnas.2532018123\">https://doi.org/10.1073/pnas.2532018123</a>.","mla":"Isakova, Lada H., et al. “Descent from a Common Ancestor Restricts Exploration of Protein Sequence Space.” <i>Proceedings of the National Academy of Sciences</i>, vol. 123, no. 14, National Academy of Sciences, 2026, p. e2532018123, doi:<a href=\"https://doi.org/10.1073/pnas.2532018123\">10.1073/pnas.2532018123</a>."},"volume":123,"acknowledgement":"We thank Olga Kalinina for feedback on our manuscript, Vsevolod Kuksin for fruitful discussions and Lev Tsarin for participation in the design of our models. This work was supported by Japan Science and Technology Agency as part of Adopting Sustainable Partnerships for Innovative Research Ecosystem, Grant No. JPMJAP24B2 (F.A.K. and L.H.I.), and Fonds Zur Förderung der Wissenschaftlichen Forschung Grant ESP253-B (O.O.B.)","external_id":{"pmid":["41915737"]},"file_date_updated":"2026-05-04T06:46:31Z","has_accepted_license":"1","oa":1,"publication":"Proceedings of the National Academy of Sciences","_id":"21704","publisher":"National Academy of Sciences","month":"04","tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)"},"year":"2026","publication_identifier":{"eissn":["1091-6490"]},"issue":"14","publication_status":"published","status":"public","date_updated":"2026-05-04T06:57:31Z","pmid":1},{"title":"An eclipsing 8.56 minutes orbital period mass-transferring binary","department":[{"_id":"IlCa"}],"abstract":[{"lang":"eng","text":"We report the discovery of ATLAS J101342.5−451656.8 (hereafter ATLAS J1013−4516), an 8.56 minute orbital-period mass-transferring AM Canum Venaticorum (AM CVn) binary with a mean Gaia magnitude of G = 19.51, identified via periodic variability in light curves from the Asteroid Terrestrial-impact Last Alert System (ATLAS) of Gaia white dwarf candidates. Follow-up with the Large Lenslet Array Magellan Spectrograph shows a helium-dominated accretion disk, and high-speed ULTRACAM photometry reveals pronounced primary and secondary eclipses. We construct a decade-long timing baseline leveraging light curves from the ATLAS and Gaia surveys, as well as the high-speed imagers ULTRACAM on the New Energy Telescope and proto-Lightspeed on the Magellan Clay telescope. From this timing baseline, we measure an orbital period derivative of P 1.60 0.07 10 = ± × 12 s s−1. Interpreted in the context of stable mass transfer, the magnitude and sign of P indicate that the orbital evolution is governed by the interplay between gravitationalwave-driven angular-momentum losses and mass transfer, directly probing the donor’s structural response to mass loss. We constrain the accretor and donor mass based on stable mass-transfer arguments assuming angularmomentum loss dominated by gravitational-wave emission, allowing us to infer the characteristic gravitational\r\nwave strain of the binary for future space-based GW observatories such as the Laser Interferometer Space Antenna (LISA). We predict a characteristic strain corresponding to a 4 yr LISA signal-to-noise ratio ≳10, establishing ATLAS J1013−4516 as a strong prospective LISA source that will probe long-term orbital evolution in the mass-transferring regime."}],"DOAJ_listed":"1","quality_controlled":"1","OA_type":"gold","doi":"10.3847/1538-4357/ae4871","article_type":"original","ddc":["520"],"oa_version":"Published Version","date_created":"2026-04-12T22:01:47Z","intvolume":"      1000","type":"journal_article","author":[{"last_name":"Chickles","first_name":"Emma T.","full_name":"Chickles, Emma T."},{"full_name":"Chakraborty, Joheen","first_name":"Joheen","last_name":"Chakraborty"},{"first_name":"Kevin B.","full_name":"Burdge, Kevin B.","last_name":"Burdge"},{"last_name":"Dhillon","full_name":"Dhillon, Vik S.","first_name":"Vik S."},{"last_name":"Draghis","full_name":"Draghis, Paul","first_name":"Paul"},{"first_name":"Kareem","full_name":"El-Badry, Kareem","last_name":"El-Badry"},{"full_name":"Green, Matthew J.","first_name":"Matthew J.","last_name":"Green"},{"first_name":"Aaron","full_name":"Householder, Aaron","last_name":"Householder"},{"last_name":"Hughes","first_name":"Sarah","full_name":"Hughes, Sarah"},{"full_name":"Layden, Christopher","first_name":"Christopher","last_name":"Layden"},{"full_name":"Littlefair, Stuart P.","first_name":"Stuart P.","last_name":"Littlefair"},{"last_name":"Munday","full_name":"Munday, James","first_name":"James"},{"first_name":"Ingrid","full_name":"Pelisoli, Ingrid","last_name":"Pelisoli"},{"last_name":"Redden","full_name":"Redden, Maya S.","first_name":"Maya S."},{"last_name":"Tonry","full_name":"Tonry, John","first_name":"John"},{"last_name":"van Roestel","full_name":"van Roestel, Joannes C","id":"4d122fc8-6083-11f0-87a5-97d68b860333","first_name":"Joannes C"},{"last_name":"Angile","full_name":"Angile, Francesco Elio","first_name":"Francesco Elio"},{"last_name":"Brown","full_name":"Brown, Alex J.","first_name":"Alex J."},{"full_name":"Segura, Noel Castro","first_name":"Noel Castro","last_name":"Segura"},{"full_name":"Dinsmore, Jack","first_name":"Jack","last_name":"Dinsmore"},{"last_name":"Dyer","first_name":"Martin","full_name":"Dyer, Martin"},{"full_name":"Furesz, Gabor","first_name":"Gabor","last_name":"Furesz"},{"full_name":"Gabutti, Michelle","first_name":"Michelle","last_name":"Gabutti"},{"last_name":"Garbutt","first_name":"James","full_name":"Garbutt, James"},{"last_name":"García-Mejía","first_name":"Juliana","full_name":"García-Mejía, Juliana"},{"last_name":"Jarvis","full_name":"Jarvis, Daniel","first_name":"Daniel"},{"last_name":"Kennedy","full_name":"Kennedy, Mark R.","first_name":"Mark R."},{"full_name":"Kerry, Paul","first_name":"Paul","last_name":"Kerry"},{"full_name":"Mccormac, James","first_name":"James","last_name":"Mccormac"},{"full_name":"Mo, Geoffrey","first_name":"Geoffrey","last_name":"Mo"},{"full_name":"Osip, Dave","first_name":"Dave","last_name":"Osip"},{"last_name":"Parsons","first_name":"Steven","full_name":"Parsons, Steven"},{"last_name":"Pike","full_name":"Pike, Eleanor","first_name":"Eleanor"},{"last_name":"Piotrowski","full_name":"Piotrowski, John J.","first_name":"John J."},{"last_name":"Romani","first_name":"Roger W.","full_name":"Romani, Roger W."},{"full_name":"Sahman, David","first_name":"David","last_name":"Sahman"},{"last_name":"Simcoe","first_name":"Rob","full_name":"Simcoe, Rob"}],"OA_place":"publisher","day":"01","status":"public","publication_status":"published","article_number":"237","issue":"2","publication_identifier":{"issn":["0004-637X"],"eissn":["1538-4357"]},"date_updated":"2026-05-04T06:37:12Z","file_date_updated":"2026-05-04T06:36:00Z","external_id":{"arxiv":["2601.07925"]},"oa":1,"has_accepted_license":"1","arxiv":1,"citation":{"ieee":"E. T. Chickles <i>et al.</i>, “An eclipsing 8.56 minutes orbital period mass-transferring binary,” <i>The Astrophysical Journal</i>, vol. 1000, no. 2. IOP Publishing, 2026.","mla":"Chickles, Emma T., et al. “An Eclipsing 8.56 Minutes Orbital Period Mass-Transferring Binary.” <i>The Astrophysical Journal</i>, vol. 1000, no. 2, 237, IOP Publishing, 2026, doi:<a href=\"https://doi.org/10.3847/1538-4357/ae4871\">10.3847/1538-4357/ae4871</a>.","chicago":"Chickles, Emma T., Joheen Chakraborty, Kevin B. Burdge, Vik S. Dhillon, Paul Draghis, Kareem El-Badry, Matthew J. Green, et al. “An Eclipsing 8.56 Minutes Orbital Period Mass-Transferring Binary.” <i>The Astrophysical Journal</i>. IOP Publishing, 2026. <a href=\"https://doi.org/10.3847/1538-4357/ae4871\">https://doi.org/10.3847/1538-4357/ae4871</a>.","ama":"Chickles ET, Chakraborty J, Burdge KB, et al. An eclipsing 8.56 minutes orbital period mass-transferring binary. <i>The Astrophysical Journal</i>. 2026;1000(2). doi:<a href=\"https://doi.org/10.3847/1538-4357/ae4871\">10.3847/1538-4357/ae4871</a>","ista":"Chickles ET, Chakraborty J, Burdge KB, Dhillon VS, Draghis P, El-Badry K, Green MJ, Householder A, Hughes S, Layden C, Littlefair SP, Munday J, Pelisoli I, Redden MS, Tonry J, van Roestel JC, Angile FE, Brown AJ, Segura NC, Dinsmore J, Dyer M, Furesz G, Gabutti M, Garbutt J, García-Mejía J, Jarvis D, Kennedy MR, Kerry P, Mccormac J, Mo G, Osip D, Parsons S, Pike E, Piotrowski JJ, Romani RW, Sahman D, Simcoe R. 2026. An eclipsing 8.56 minutes orbital period mass-transferring binary. The Astrophysical Journal. 1000(2), 237.","apa":"Chickles, E. T., Chakraborty, J., Burdge, K. B., Dhillon, V. S., Draghis, P., El-Badry, K., … Simcoe, R. (2026). An eclipsing 8.56 minutes orbital period mass-transferring binary. <i>The Astrophysical Journal</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/1538-4357/ae4871\">https://doi.org/10.3847/1538-4357/ae4871</a>","short":"E.T. Chickles, J. Chakraborty, K.B. Burdge, V.S. Dhillon, P. Draghis, K. El-Badry, M.J. Green, A. Householder, S. Hughes, C. Layden, S.P. Littlefair, J. Munday, I. Pelisoli, M.S. Redden, J. Tonry, J.C. van Roestel, F.E. Angile, A.J. Brown, N.C. Segura, J. Dinsmore, M. Dyer, G. Furesz, M. Gabutti, J. Garbutt, J. García-Mejía, D. Jarvis, M.R. Kennedy, P. Kerry, J. Mccormac, G. Mo, D. Osip, S. Parsons, E. Pike, J.J. Piotrowski, R.W. Romani, D. Sahman, R. Simcoe, The Astrophysical Journal 1000 (2026)."},"article_processing_charge":"Yes","volume":1000,"acknowledgement":"This work has made use of data from the Asteroid Terrestrial-impact Last Alert System (ATLAS) project. The Asteroid Terrestrial-impact Last Alert System (ATLAS) project is primarily funded to search for near-Earth asteroids through NASA grants NN12AR55G, 80NSSC18K0284, and 80NSSC18K1575; byproducts of the NEO search include images and catalogs from the survey area. This work was partially funded by Kepler/K2 grant J1944/80NSSC19K0112 and HST GO-15889 and STFC grants ST/T000198/1 and ST/S006109/1. The ATLAS science products have been made possible through the contributions of the University of Hawaii Institute for Astronomy, the Queen’s University Belfast, the Space Telescope Science Institute, the South African Astronomical Observatory, and the Millennium Institute of Astrophysics (MAS), Chile. VSD and ULTRACAM are supported by STFC grant ST/Z000033/1. J.G.M. gratefully acknowledges support from the Heising-Simons Foundation and the Pappalardo family through the MIT Pappalardo Fellowship in Physics.","fulldoi":"https://doi.org/10.3847/1538-4357/ae4871","date_published":"2026-04-01T00:00:00Z","language":[{"iso":"eng"}],"scopus_import":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"access_level":"open_access","content_type":"application/pdf","file_id":"21782","date_updated":"2026-05-04T06:36:00Z","file_name":"2026_AstrophysicalJournal_Chickles.pdf","file_size":1225916,"creator":"dernst","date_created":"2026-05-04T06:36:00Z","success":1,"checksum":"c8f64a78f36224d8e0ea1f324e43e389","relation":"main_file"}],"year":"2026","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"publisher":"IOP Publishing","month":"04","_id":"21705","publication":"The Astrophysical Journal"},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"date_created":"2026-05-04T09:16:36Z","checksum":"3eed470fe73e53d2a8d55d6fba6934e3","success":1,"relation":"main_file","access_level":"open_access","content_type":"application/pdf","date_updated":"2026-05-04T09:16:36Z","file_id":"21786","creator":"dernst","file_name":"2026_ScienceAdv_Markovitsch.pdf","file_size":11101140}],"date_published":"2026-03-27T00:00:00Z","fulldoi":"https://doi.org/10.1126/sciadv.aea6020","language":[{"iso":"eng"}],"scopus_import":"1","citation":{"chicago":"Markovitsch, Johann W., Daniel Mitić, Alisa Del Pilar Jiménez García, Alsberga Zane, Sarah Kainz, Rashmit Kaur, and Thomas Hummel. “Sequential Formation of Drosophila Circuit Asymmetry via Prolonged Structural Plasticity.” <i>Science Advances</i>. American Association for the Advancement of Science, 2026. <a href=\"https://doi.org/10.1126/sciadv.aea6020\">https://doi.org/10.1126/sciadv.aea6020</a>.","mla":"Markovitsch, Johann W., et al. “Sequential Formation of Drosophila Circuit Asymmetry via Prolonged Structural Plasticity.” <i>Science Advances</i>, vol. 12, no. 13, eaea6020, American Association for the Advancement of Science, 2026, doi:<a href=\"https://doi.org/10.1126/sciadv.aea6020\">10.1126/sciadv.aea6020</a>.","ieee":"J. W. Markovitsch <i>et al.</i>, “Sequential formation of Drosophila circuit asymmetry via prolonged structural plasticity,” <i>Science Advances</i>, vol. 12, no. 13. American Association for the Advancement of Science, 2026.","short":"J.W. Markovitsch, D. Mitić, A. Del Pilar Jiménez García, A. Zane, S. Kainz, R. Kaur, T. Hummel, Science Advances 12 (2026).","apa":"Markovitsch, J. W., Mitić, D., Del Pilar Jiménez García, A., Zane, A., Kainz, S., Kaur, R., &#38; Hummel, T. (2026). Sequential formation of Drosophila circuit asymmetry via prolonged structural plasticity. <i>Science Advances</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/sciadv.aea6020\">https://doi.org/10.1126/sciadv.aea6020</a>","ama":"Markovitsch JW, Mitić D, Del Pilar Jiménez García A, et al. Sequential formation of Drosophila circuit asymmetry via prolonged structural plasticity. <i>Science Advances</i>. 2026;12(13). doi:<a href=\"https://doi.org/10.1126/sciadv.aea6020\">10.1126/sciadv.aea6020</a>","ista":"Markovitsch JW, Mitić D, Del Pilar Jiménez García A, Zane A, Kainz S, Kaur R, Hummel T. 2026. Sequential formation of Drosophila circuit asymmetry via prolonged structural plasticity. Science Advances. 12(13), eaea6020."},"article_processing_charge":"Yes","volume":12,"acknowledgement":"We thank I. Salecker (Flybow), B. Altenhein (Fas2-Gal4Mz507), A. Nose (UAS-intra- and extra-Fas2::YFP), and C. S. Goodman (UAS-Fas2PEST+/−), as well as the Bloomington Stock Center for providing materials and fly stocks. We thank S. Waddell and the lab, especially B. Senapati, for providing the opportunity to conduct memory experiments at the CNCB, University of Oxford, and for supervision and discussions during this period. We also thank W. Kallina, S. Ilgerl, D. Bartel, A. Grimm, and A. Litin for technical support and the Hummel Lab for stimulating discussions and critical comments on the manuscript. We acknowledge the early exploratory work of A. Mattia, S. Trkulja, C. Schönherr, S. Bogner, B. Simpson, L. Tomasek, H. Roth, H. Vokač, R. Gredler, F. Kapelari, T. Kolarova, C. Ignitsch, Á. Bautista-Soldevila, and M. Kassem.\r\nThis research was funded by the University of Vienna, the Vienna Doctoral School Cognition, Behaviour and Neuroscience (uni:docs fellowship) (to J.W.M.) and by the Austrian Science Fund (FWF) (Cluster of Excellence Neuronal Circuits in Health and Disease, grant DOI 10.55776/COE16; https://www.fwf.ac.at/en/research-radar/10.55776/COE16) (to T.H.). For open access purposes, the author has applied a CC BY public copyright license to any author-accepted manuscript version arising from this submission.","file_date_updated":"2026-05-04T09:16:36Z","oa":1,"has_accepted_license":"1","publication":"Science Advances","_id":"21707","publisher":"American Association for the Advancement of Science","month":"03","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"year":"2026","publication_identifier":{"eissn":["2375-2548"]},"issue":"13","article_number":"eaea6020","publication_status":"published","status":"public","date_updated":"2026-05-04T09:18:06Z","OA_place":"publisher","author":[{"last_name":"Markovitsch","first_name":"Johann W.","full_name":"Markovitsch, Johann W."},{"full_name":"Mitić, Daniel","first_name":"Daniel","last_name":"Mitić"},{"last_name":"Del Pilar Jiménez García","first_name":"Alisa","full_name":"Del Pilar Jiménez García, Alisa"},{"id":"60f7509a-f652-11ea-9d86-b963d6490d7c","full_name":"Zane, Alsberga","first_name":"Alsberga","orcid":"0009-0003-0415-7603","last_name":"Zane"},{"full_name":"Kainz, Sarah","first_name":"Sarah","last_name":"Kainz"},{"last_name":"Kaur","full_name":"Kaur, Rashmit","first_name":"Rashmit"},{"last_name":"Hummel","first_name":"Thomas","full_name":"Hummel, Thomas"}],"type":"journal_article","intvolume":"        12","date_created":"2026-04-12T22:01:48Z","day":"27","quality_controlled":"1","OA_type":"gold","abstract":[{"text":"Structural and functional differences between brain hemispheres are a common feature of animal nervous systems with reduced bilateral asymmetry often linked to impaired cognitive performance. How neuronal left-right asymmetry is initiated and integrated into a bilaterally symmetrical ground pattern is poorly understood. Here, we show that the directional asymmetry of a Drosophila central brain circuit originates from axonal interactions of two types of bilateral pioneer neurons. Subsequent recruitment of neighboring neurons into the asymmetric neuropil primordium results in hemisphere-specific microcircuits. Circuit lateralization requires dynamic expression of the cell adhesion molecule Fasciclin 2 to maintain structural plasticity in axonal remodeling. Reduced circuit asymmetry following cell type–specific Fasciclin 2 manipulation affects adult brain function. These results reveal an unexpected degree of developmental plasticity of late-born Drosophila neurons in the formation of a circuit node via the lateralized recruitment of symmetric circuit components.","lang":"eng"}],"DOAJ_listed":"1","department":[{"_id":"MiSi"},{"_id":"GradSch"}],"title":"Sequential formation of Drosophila circuit asymmetry via prolonged structural plasticity","ddc":["570"],"oa_version":"Published Version","article_type":"original","doi":"10.1126/sciadv.aea6020"},{"pmid":1,"date_updated":"2026-05-04T07:54:53Z","status":"public","article_number":"9741","publication_status":"published","publication_identifier":{"eissn":["2045-2322"]},"tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)"},"year":"2026","publisher":"Springer Nature","month":"03","_id":"21708","publication":"Scientific Reports","file_date_updated":"2026-05-04T07:24:59Z","external_id":{"pmid":["41876546"]},"has_accepted_license":"1","oa":1,"citation":{"short":"L.K. Mohanty, P. GANTAYAT, A. Dixit, M. Das Adhikari, R. Biswas, V.K. Singh, Scientific Reports 16 (2026).","apa":"Mohanty, L. K., GANTAYAT, P., Dixit, A., Das Adhikari, M., Biswas, R., &#38; Singh, V. K. (2026). Sequence of events that led to the South Lhonak lake outburst flood in Sikkim, India. <i>Scientific Reports</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41598-026-35895-7\">https://doi.org/10.1038/s41598-026-35895-7</a>","ama":"Mohanty LK, GANTAYAT P, Dixit A, Das Adhikari M, Biswas R, Singh VK. Sequence of events that led to the South Lhonak lake outburst flood in Sikkim, India. <i>Scientific Reports</i>. 2026;16. doi:<a href=\"https://doi.org/10.1038/s41598-026-35895-7\">10.1038/s41598-026-35895-7</a>","ista":"Mohanty LK, GANTAYAT P, Dixit A, Das Adhikari M, Biswas R, Singh VK. 2026. Sequence of events that led to the South Lhonak lake outburst flood in Sikkim, India. Scientific Reports. 16, 9741.","chicago":"Mohanty, Litan Kumar, PRATEEK GANTAYAT, Ankur Dixit, Manik Das Adhikari, Rahul Biswas, and Vivek Kumar Singh. “Sequence of Events That Led to the South Lhonak Lake Outburst Flood in Sikkim, India.” <i>Scientific Reports</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41598-026-35895-7\">https://doi.org/10.1038/s41598-026-35895-7</a>.","mla":"Mohanty, Litan Kumar, et al. “Sequence of Events That Led to the South Lhonak Lake Outburst Flood in Sikkim, India.” <i>Scientific Reports</i>, vol. 16, 9741, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41598-026-35895-7\">10.1038/s41598-026-35895-7</a>.","ieee":"L. K. Mohanty, P. GANTAYAT, A. Dixit, M. Das Adhikari, R. Biswas, and V. K. Singh, “Sequence of events that led to the South Lhonak lake outburst flood in Sikkim, India,” <i>Scientific Reports</i>, vol. 16. Springer Nature, 2026."},"article_processing_charge":"Yes","volume":16,"acknowledgement":"This work was carried out independently without the support of any funding agency or sponsors. The authors thank the SARPROZ team for providing an evaluation license for the MTInSAR processing software.","fulldoi":"https://doi.org/10.1038/s41598-026-35895-7","language":[{"iso":"eng"}],"scopus_import":"1","date_published":"2026-03-24T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"date_created":"2026-05-04T07:24:59Z","relation":"main_file","checksum":"cf13f61c38609ce6518d74562319c35f","success":1,"content_type":"application/pdf","access_level":"open_access","file_name":"2026_ScienceAdv_Mohanty.pdf","file_size":17406006,"creator":"dernst","file_id":"21785","date_updated":"2026-05-04T07:24:59Z"}],"article_type":"original","doi":"10.1038/s41598-026-35895-7","ddc":["550"],"oa_version":"Published Version","title":"Sequence of events that led to the South Lhonak lake outburst flood in Sikkim, India","department":[{"_id":"FrPe"}],"DOAJ_listed":"1","abstract":[{"lang":"eng","text":"On October 4, 2023, a proglacial lake named the South Lhonak lake was the source of a catastrophic Glacier Lake Outburst Flood (GLOF) in the Teesta river basin area, resulting in 24 fatalities and leaving over 70 persons missing. The GLOF also destroyed 13 bridges and a major hydropower plant in the Chungthang region. Over 60,000 individuals in four districts of Sikkim were impacted by this GLOF event. This study examines the factors that led to the GLOF event. Our study shows that the cause of this GLOF was initiated by a landslide, that dumped a substantial amount (~ 38.31 million m3) of debris into the South Lhonak Lake. Furthermore, the glacier that was connected to the lake, lost a big chunk of ice mass (~ 7 million m3) due to calving. The combination of these two processes led to the collapse of the left lateral moraine that consequently generated flood waves which breached the terminal moraine dam of the lake. We recommend monitoring land subsidence and calving events for large proglacial lakes to prevent the disastrous consequences of such GLOFs in the future."}],"quality_controlled":"1","OA_type":"gold","day":"24","corr_author":"1","date_created":"2026-04-12T22:01:48Z","intvolume":"        16","type":"journal_article","author":[{"last_name":"Mohanty","full_name":"Mohanty, Litan Kumar","first_name":"Litan Kumar"},{"first_name":"Prateek","full_name":"Gantayat, Prateek","id":"02734268-3e8d-11ef-80a1-cec4a088d004","last_name":"Gantayat"},{"last_name":"Dixit","full_name":"Dixit, Ankur","first_name":"Ankur"},{"last_name":"Das Adhikari","first_name":"Manik","full_name":"Das Adhikari, Manik"},{"first_name":"Rahul","full_name":"Biswas, Rahul","last_name":"Biswas"},{"first_name":"Vivek Kumar","full_name":"Singh, Vivek Kumar","last_name":"Singh"}],"OA_place":"publisher"},{"day":"20","date_created":"2026-04-12T22:01:48Z","type":"journal_article","intvolume":"      1000","OA_place":"publisher","author":[{"last_name":"Hviding","full_name":"Hviding, Raphael E.","first_name":"Raphael E."},{"last_name":"De Graaff","full_name":"De Graaff, Anna","first_name":"Anna"},{"last_name":"Liu","first_name":"Hanpu","full_name":"Liu, Hanpu"},{"last_name":"Goulding","full_name":"Goulding, Andy D.","first_name":"Andy D."},{"last_name":"Ma","first_name":"Yilun","full_name":"Ma, Yilun"},{"last_name":"Greene","full_name":"Greene, Jenny E.","first_name":"Jenny E."},{"last_name":"Boogaard","full_name":"Boogaard, Leindert A.","first_name":"Leindert A."},{"full_name":"Bunker, Andrew J.","first_name":"Andrew J.","last_name":"Bunker"},{"last_name":"Cleri","first_name":"Nikko J.","full_name":"Cleri, Nikko J."},{"last_name":"Franx","full_name":"Franx, Marijn","first_name":"Marijn"},{"full_name":"Hirschmann, Michaela","first_name":"Michaela","last_name":"Hirschmann"},{"last_name":"Leja","full_name":"Leja, Joel","first_name":"Joel"},{"first_name":"Jorryt J","full_name":"Matthee, Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720","orcid":"0000-0003-2871-127X","last_name":"Matthee"},{"first_name":"Rohan P.","full_name":"Naidu, Rohan P.","last_name":"Naidu"},{"full_name":"Setton, David J.","first_name":"David J.","last_name":"Setton"},{"last_name":"Übler","full_name":"Übler, Hannah","first_name":"Hannah"},{"first_name":"Giacomo","full_name":"Venturi, Giacomo","last_name":"Venturi"},{"last_name":"Wang","full_name":"Wang, Bingjie","first_name":"Bingjie"}],"doi":"10.3847/2041-8213/ae4c88","article_type":"original","ddc":["520"],"oa_version":"Published Version","department":[{"_id":"JoMa"}],"title":"The X-ray dot: Exotic dust or a late-stage Little Red Dot?","abstract":[{"text":"JWST’s “little red dots” (LRDs) are increasingly interpreted as active galactic nuclei (AGN) obscured by dense thermalized gas rather than dust as evidenced by their X-ray weakness, blackbody-like continua, and Balmer line profiles. Key questions are how LRDs connect to standard UV-luminous AGN, whether transitional phases exist, and whether they are observable. We present the “X-ray dot” (XRD), a compact source at z = 3.28 observed by the NIRSpec Wide Guaranteed Time Observation survey. The XRD exhibits LRD hallmarks: a blackbody-like (Teff ≃ 6400 K) red continuum, a faint but blue rest-UV excess, falling mid-IR emission, and broad Balmer lines (FWHM ∼ 2700–3200 km s−1). Unlike LRDs, however, it is remarkably X-ray luminous (L2−10 keV = 1044.18 erg s−1) and has a continuum inflection that is blueward of the Balmer limit. We find that the red rest-optical and blue mid-IR continuum cannot be reproduced by standard dust-attenuated AGN models without invoking extremely steep extinction curves, nor can the weak mid-IR emission be reconciled with well-established X-ray–torus scaling relations. We therefore consider an alternative scenario: the XRD may be an LRD in transition, where the gas envelope dominates the optical continuum but optically thin sight lines allow X-rays to escape. The XRD may thus provide a physical link between LRDs and standard AGN, offering direct evidence that LRDs are powered by supermassive black holes and providing insight into their accretion properties.","lang":"eng"}],"DOAJ_listed":"1","OA_type":"gold","quality_controlled":"1","year":"2026","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"month":"03","publisher":"IOP Publishing","_id":"21709","publication":"The Astrophysical Journal Letters","has_accepted_license":"1","arxiv":1,"oa":1,"external_id":{"arxiv":["2601.09778"]},"file_date_updated":"2026-05-04T07:11:37Z","acknowledgement":"We would like to thank the anonymous reviewer for their constructive comments, which improved the final manuscript.\r\n\r\nWe thank Bernd Husemann for his critical contributions to the NIRSpec Wide GTO survey, and in particular his help in selecting high-priority X-ray-luminous targets.\r\n\r\nR.E.H. acknowledges support by the German Aerospace Center (DLR) and the Federal Ministry for Economic Affairs and Energy (BMWi) through program 50OR2403 “RUBIES.” A.d.G. acknowledges support from a Clay Fellowship awarded by the Smithsonian Astrophysical Observatory. A.J.B. acknowledges funding from the “FirstGalaxies” Advanced grant from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (grant agreement No. 789056). R.P.N. thanks Neil Pappalardo and Jane Pappalardo for their generous support of the MIT Pappalardo Fellowships in Physics. Support for this work was provided by the Brinson Foundation through a Brinson Prize Fellowship grant. H.Ü. acknowledges funding by the European Union (ERC APEX, 101164796). Views and opinions expressed are, however, those of the authors only and do not necessarily reflect those of the European Union or the European Research Council Executive Agency. Neither the European Union nor the granting authority can be held responsible for them. G.V. acknowledges support from European Union’s HE ERC Starting grant No. 101040227—WINGS. B.W. acknowledges support provided by NASA through Hubble Fellowship grant HST-HF2-51592.001 awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, In., for NASA, under the contract NAS 5-26555.\r\n\r\nThe data products presented herein were retrieved from the Dawn JWST Archive (DJA). DJA is an initiative of the Cosmic Dawn Center (DAWN).\r\n\r\nThis work is based in part on observations made with the NASA/ESA/CSA James Webb Space Telescope. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with programs Nos. GTO-1213. The data described here may be obtained from the MAST archive at DOI: 10.17909/qffz-b324.\r\n\r\nThis Letter employs a list of Chandra datasets, obtained by the Chandra X-ray Observatory, contained in DOI: 10.25574/cdc.540.\r\n\r\nThis work is based on observations taken by the 3D-HST Treasury Program (GO 12177 and 12328) with the NASA/ESA HST, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS5-26555.\r\n\r\nThis work makes use of color palettes created by Martin Krzywinski designed for colorblindness. The color palettes and more information can be found at http://mkweb.bcgsc.ca/colorblind/.\r\n\r\nFacilities: CXO - Chandra X-ray Observatory satellite (ACIS), HST - Hubble Space Telescope satellite (ACS, WFC3) - , CFHT - Canada-France-Hawaii Telescope (WIRCam), JWST - James Webb Space Telescope (NIRSpec), Spitzer - Spitzer Space Telescope satellite (IRAC, MIPS) - , JCMT - James Clerk Maxwell Telescope (SCUBA).\r\n\r\nSoftware: Astropy (Astropy Collaboration et al. 2013, 2018, 2022), dust_attenuation, dust_extinction (K. Gordon 2024), jax (J. Bradbury et al. 2018), LaTeX (L. Lamport 1994), Matplotlib (J. D. Hunter 2007), NumPy (T. E. Oliphant 2006; S. van der Walt et al. 2011; C. R. Harris et al. 2020), NumPyro (D. Phan et al. 2019), scipy (P. Virtanen et al. 2020), sedpy (B. Johnson & J. Leja 2017), specutils (Astropy-Specutils Development Team 2019), unite (R. E. Hviding 2025).","article_processing_charge":"Yes","citation":{"chicago":"Hviding, Raphael E., Anna De Graaff, Hanpu Liu, Andy D. Goulding, Yilun Ma, Jenny E. Greene, Leindert A. Boogaard, et al. “The X-Ray Dot: Exotic Dust or a Late-Stage Little Red Dot?” <i>The Astrophysical Journal Letters</i>. IOP Publishing, 2026. <a href=\"https://doi.org/10.3847/2041-8213/ae4c88\">https://doi.org/10.3847/2041-8213/ae4c88</a>.","mla":"Hviding, Raphael E., et al. “The X-Ray Dot: Exotic Dust or a Late-Stage Little Red Dot?” <i>The Astrophysical Journal Letters</i>, vol. 1000, no. 1, L18, IOP Publishing, 2026, doi:<a href=\"https://doi.org/10.3847/2041-8213/ae4c88\">10.3847/2041-8213/ae4c88</a>.","ieee":"R. E. Hviding <i>et al.</i>, “The X-ray dot: Exotic dust or a late-stage Little Red Dot?,” <i>The Astrophysical Journal Letters</i>, vol. 1000, no. 1. IOP Publishing, 2026.","short":"R.E. Hviding, A. De Graaff, H. Liu, A.D. Goulding, Y. Ma, J.E. Greene, L.A. Boogaard, A.J. Bunker, N.J. Cleri, M. Franx, M. Hirschmann, J. Leja, J.J. Matthee, R.P. Naidu, D.J. Setton, H. Übler, G. Venturi, B. Wang, The Astrophysical Journal Letters 1000 (2026).","apa":"Hviding, R. E., De Graaff, A., Liu, H., Goulding, A. D., Ma, Y., Greene, J. E., … Wang, B. (2026). The X-ray dot: Exotic dust or a late-stage Little Red Dot? <i>The Astrophysical Journal Letters</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/2041-8213/ae4c88\">https://doi.org/10.3847/2041-8213/ae4c88</a>","ama":"Hviding RE, De Graaff A, Liu H, et al. The X-ray dot: Exotic dust or a late-stage Little Red Dot? <i>The Astrophysical Journal Letters</i>. 2026;1000(1). doi:<a href=\"https://doi.org/10.3847/2041-8213/ae4c88\">10.3847/2041-8213/ae4c88</a>","ista":"Hviding RE, De Graaff A, Liu H, Goulding AD, Ma Y, Greene JE, Boogaard LA, Bunker AJ, Cleri NJ, Franx M, Hirschmann M, Leja J, Matthee JJ, Naidu RP, Setton DJ, Übler H, Venturi G, Wang B. 2026. The X-ray dot: Exotic dust or a late-stage Little Red Dot? The Astrophysical Journal Letters. 1000(1), L18."},"volume":1000,"fulldoi":"https://doi.org/10.3847/2041-8213/ae4c88","date_published":"2026-03-20T00:00:00Z","language":[{"iso":"eng"}],"scopus_import":"1","file":[{"access_level":"open_access","content_type":"application/pdf","date_updated":"2026-05-04T07:11:37Z","file_id":"21784","creator":"dernst","file_name":"2026_AstrophysicalJourLetters_Hviding.pdf","file_size":2821786,"date_created":"2026-05-04T07:11:37Z","success":1,"checksum":"1be4f361bf59aa08b8c98ed4f475a463","relation":"main_file"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2026-05-04T07:13:07Z","status":"public","publication_status":"published","article_number":"L18","issue":"1","publication_identifier":{"issn":["2041-8205"],"eissn":["2041-8213"]}}]