---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21752'
abstract:
- lang: eng
  text: Epithelial tissues function as multicellular communities that preserve tissue
    integrity while adapting to diverse environmental stresses by altering cell behaviors.
    A striking manifestation of such adaptability is cell plasticity, the ability
    of differentiated cells to revert to stem-like states or adopt alternative fates.
    Once considered rare and confined to highly regenerative species, cell plasticity
    is now recognized across the metazoan tree. In early-branching animals such as
    sponges and cnidarians, transdifferentiation and dedifferentiation are integral
    to life-cycle transitions and regeneration, whereas in more complex organisms,
    these processes typically emerge under stress, including stem cell loss or environmental
    perturbations. Here, we examine epithelial cell plasticity through evolutionary,
    cellular, and molecular perspectives. Focusing on the intestinal epithelium, we
    explore findings from mammalian and Drosophila models showing that progenitors
    and even terminally differentiated cells can dedifferentiate in response to external
    stimuli that disrupt homeostasis, such as pathogen infection and nutrient fluctuations.
    We further discuss conserved mechanisms involving intercellular signaling (e.g.,
    Notch, EGFR, and JAK-STAT) and chromatin states primed for reprogramming, modulated
    by metabolic cues. Together, these insights position cell plasticity as an ancient
    environmental adaptation strategy, shaped by conserved molecular toolkits and
    refined by species- and cell lineage-specific innovations.
acknowledgement: This work was supported by JSPS/MEXT KAKENHI (grant numbers JP22J01430
  to H.N., JP23H04696, JP23K24025, JP25H02543, JP25K02406 to Y.N.), JST FOREST Program
  JPMJFR233E (Y.N.), The Cell Science Research Foundation (Y.N.), and Takeda Science
  Foundation (Y.N.).
article_number: '103670'
article_processing_charge: Yes (in subscription journal)
article_type: review
author:
- first_name: Hiroki
  full_name: Nagai, Hiroki
  id: 608df3e6-e2ab-11ed-8890-c9318cec7da4
  last_name: Nagai
  orcid: 0000-0003-1671-9434
- first_name: Yu Ichiro
  full_name: Nakajima, Yu Ichiro
  last_name: Nakajima
citation:
  ama: 'NAGAI H, Nakajima YI. Epithelial cell plasticity in metazoans: Evolutionary
    insights into roles and mechanisms. <i>Seminars in Cell and Developmental Biology</i>.
    2026;179-180. doi:<a href="https://doi.org/10.1016/j.semcdb.2026.103670">10.1016/j.semcdb.2026.103670</a>'
  apa: 'NAGAI, H., &#38; Nakajima, Y. I. (2026). Epithelial cell plasticity in metazoans:
    Evolutionary insights into roles and mechanisms. <i>Seminars in Cell and Developmental
    Biology</i>. Elsevier. <a href="https://doi.org/10.1016/j.semcdb.2026.103670">https://doi.org/10.1016/j.semcdb.2026.103670</a>'
  chicago: 'NAGAI, HIROKI, and Yu Ichiro Nakajima. “Epithelial Cell Plasticity in
    Metazoans: Evolutionary Insights into Roles and Mechanisms.” <i>Seminars in Cell
    and Developmental Biology</i>. Elsevier, 2026. <a href="https://doi.org/10.1016/j.semcdb.2026.103670">https://doi.org/10.1016/j.semcdb.2026.103670</a>.'
  ieee: 'H. NAGAI and Y. I. Nakajima, “Epithelial cell plasticity in metazoans: Evolutionary
    insights into roles and mechanisms,” <i>Seminars in Cell and Developmental Biology</i>,
    vol. 179–180. Elsevier, 2026.'
  ista: 'NAGAI H, Nakajima YI. 2026. Epithelial cell plasticity in metazoans: Evolutionary
    insights into roles and mechanisms. Seminars in Cell and Developmental Biology.
    179–180, 103670.'
  mla: 'NAGAI, HIROKI, and Yu Ichiro Nakajima. “Epithelial Cell Plasticity in Metazoans:
    Evolutionary Insights into Roles and Mechanisms.” <i>Seminars in Cell and Developmental
    Biology</i>, vol. 179–180, 103670, Elsevier, 2026, doi:<a href="https://doi.org/10.1016/j.semcdb.2026.103670">10.1016/j.semcdb.2026.103670</a>.'
  short: H. NAGAI, Y.I. Nakajima, Seminars in Cell and Developmental Biology 179–180
    (2026).
corr_author: '1'
date_created: 2026-04-19T22:07:49Z
date_published: 2026-05-01T00:00:00Z
date_updated: 2026-04-28T14:11:13Z
day: '01'
ddc:
- '570'
department:
- _id: XiFe
doi: 10.1016/j.semcdb.2026.103670
file:
- access_level: open_access
  checksum: 0a0929a045d0cbd964297768833c14ae
  content_type: application/pdf
  creator: dernst
  date_created: 2026-04-28T13:58:47Z
  date_updated: 2026-04-28T13:58:47Z
  file_id: '21775'
  file_name: 2026_SeminarsCellDevBiology_Nagai.pdf
  file_size: 1306613
  relation: main_file
  success: 1
file_date_updated: 2026-04-28T13:58:47Z
has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '05'
oa: 1
oa_version: Published Version
publication: Seminars in Cell and Developmental Biology
publication_identifier:
  eissn:
  - 1096-3634
  issn:
  - 1084-9521
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Epithelial cell plasticity in metazoans: Evolutionary insights into roles
  and mechanisms'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 179-180
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21755'
abstract:
- lang: eng
  text: Tropical shallow clouds are a major source of uncertainty in Earth's climate
    sensitivity, especially through their spatial arrangement, which global climate
    models do not represent. Efforts to understand their organization have partly
    relied on classifying observed scenes, identifying four patterns as archetypal
    regimes. Here we analyze geostationary satellite imagery of the western tropical
    Atlantic using the L‐function, a tool based on point pattern theory that quantifies
    cloud organization across spatial scales. Classical examples of the four patterns
    show distinct L‐function fingerprints, revealing their characteristic clustering
    and regularity scales and aiding physical interpretation. Yet, when evaluating
    many scenes at fixed spatial scales, the L‐function distribution lacks the distinct
    modes expected from discrete regimes. This is corroborated by analyses of other
    organization indices employing diverse approaches, from inter‐cloud nearest‐neighbor
    distances to fractal analysis. Implications for the parameterization of mesoscale
    cloud organization in climate models are discussed.
acknowledgement: GB was supported by an ICTP Postdoctoral Research Fellowship Agreement.
  GM was supported by the CNRS. AC was supported by the European Union's Horizon 2020
  research and innovation programme Marie Sklodowska-Curie Grant agreement No 101034413.
  LJF acknowledges funding from the NERC Doctoral Training Partnership in Environmental
  Research Grant NE/S007474/1. We thank three anonymous reviewers and Jiawei Bao for
  their insightful comments, which greatly improved this manuscript.
article_number: e2025GL119921
article_processing_charge: Yes
article_type: original
author:
- first_name: Giovanni
  full_name: Biagioli, Giovanni
  last_name: Biagioli
- first_name: Giulio
  full_name: Mandorli, Giulio
  last_name: Mandorli
- first_name: Lilli Johanna
  full_name: Freischem, Lilli Johanna
  last_name: Freischem
- first_name: Alejandro
  full_name: Casallas Garcia, Alejandro
  id: 92081129-2d75-11ef-a48d-b04dd7a2385a
  last_name: Casallas Garcia
  orcid: 0000-0002-1988-5035
- first_name: Adrian Mark
  full_name: Tompkins, Adrian Mark
  last_name: Tompkins
citation:
  ama: 'Biagioli G, Mandorli G, Freischem LJ, Casallas Garcia A, Tompkins AM. Spatial
    patterns of shallow clouds: Challenging the concept of defined regimes. <i>Geophysical
    Research Letters</i>. 2026;53(8). doi:<a href="https://doi.org/10.1029/2025gl119921">10.1029/2025gl119921</a>'
  apa: 'Biagioli, G., Mandorli, G., Freischem, L. J., Casallas Garcia, A., &#38; Tompkins,
    A. M. (2026). Spatial patterns of shallow clouds: Challenging the concept of defined
    regimes. <i>Geophysical Research Letters</i>. Wiley. <a href="https://doi.org/10.1029/2025gl119921">https://doi.org/10.1029/2025gl119921</a>'
  chicago: 'Biagioli, Giovanni, Giulio Mandorli, Lilli Johanna Freischem, Alejandro
    Casallas Garcia, and Adrian Mark Tompkins. “Spatial Patterns of Shallow Clouds:
    Challenging the Concept of Defined Regimes.” <i>Geophysical Research Letters</i>.
    Wiley, 2026. <a href="https://doi.org/10.1029/2025gl119921">https://doi.org/10.1029/2025gl119921</a>.'
  ieee: 'G. Biagioli, G. Mandorli, L. J. Freischem, A. Casallas Garcia, and A. M.
    Tompkins, “Spatial patterns of shallow clouds: Challenging the concept of defined
    regimes,” <i>Geophysical Research Letters</i>, vol. 53, no. 8. Wiley, 2026.'
  ista: 'Biagioli G, Mandorli G, Freischem LJ, Casallas Garcia A, Tompkins AM. 2026.
    Spatial patterns of shallow clouds: Challenging the concept of defined regimes.
    Geophysical Research Letters. 53(8), e2025GL119921.'
  mla: 'Biagioli, Giovanni, et al. “Spatial Patterns of Shallow Clouds: Challenging
    the Concept of Defined Regimes.” <i>Geophysical Research Letters</i>, vol. 53,
    no. 8, e2025GL119921, Wiley, 2026, doi:<a href="https://doi.org/10.1029/2025gl119921">10.1029/2025gl119921</a>.'
  short: G. Biagioli, G. Mandorli, L.J. Freischem, A. Casallas Garcia, A.M. Tompkins,
    Geophysical Research Letters 53 (2026).
date_created: 2026-04-21T06:04:41Z
date_published: 2026-04-28T00:00:00Z
date_updated: 2026-04-28T13:35:53Z
day: '28'
ddc:
- '550'
department:
- _id: CaMu
doi: 10.1029/2025gl119921
ec_funded: 1
file:
- access_level: open_access
  checksum: 2cd4ae120b14b244f5b2f50eaae0efc1
  content_type: application/pdf
  creator: acasalla
  date_created: 2026-04-21T06:07:22Z
  date_updated: 2026-04-21T06:07:22Z
  file_id: '21756'
  file_name: Gio_Casallas_2026.pdf
  file_size: 1544417
  relation: main_file
  success: 1
file_date_updated: 2026-04-21T06:07:22Z
has_accepted_license: '1'
intvolume: '        53'
issue: '8'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
publication: Geophysical Research Letters
publication_identifier:
  eissn:
  - 1944-8007
  issn:
  - 0094-8276
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Spatial patterns of shallow clouds: Challenging the concept of defined regimes'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 53
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21760'
abstract:
- lang: eng
  text: 3I/ATLAS is the third interstellar object discovered to date, following 1I/‘Oumuamua
    and 2I/Borisov. Its unusually high excess velocity and active cometary nature
    make it a key probe of the Galactic population of icy planetesimals. Understanding
    its origin requires its past trajectory through the Galaxy to be traced and the
    possible role of stellar encounters to be assessed, both as a potential origin
    and a perturber to its orbit. We integrated the orbit of 3I/ATLAS backward in
    time for 10 Myr, together with a sample of Gaia DR3 stars with high-quality astrometry
    and radial velocities, to identify close passages within 2 pc. We identify 93
    nominal encounters, 62 of which are significant at the 2σ level. However, none
    of these encounters produced any meaningful perturbation. The strongest perturber
    Gaia DR3 6863591389529611264 at 0.30 pc and with a relative velocity of 35 km
    s−1, imparted only a velocity change of ∣Δv∣  ≃  5  ×  10−4 km s−1 to the orbit
    of 3I/ATLAS. Our results indicate that no stellar flybys within the past 10 Myr
    and 500 pc contained in Gaia DR3 can account for the present trajectory of 3I/ATLAS
    or be associated with its origin. We further show that 3I/ATLAS is kinematically
    consistent with a thin-disk population, despite its large peculiar velocity.
acknowledgement: We thank the anonymous referee for a careful reading of the manuscript
  and for constructive comments that improved the paper. X.P.C. and S.T. thank J.L.
  Gragera-Más and Ylva Götberg for their valuable feedback and comments. X.P.C. acknowledges
  financial support from the Spanish National Programme for the Promotion of Talent
  and its Employability grant PRE2022-104959 cofunded by the European Social Fund.
  S.T. acknowledges the funding from the European Union’s Horizon 2020 research and
  innovation program under the Marie Skłodowska-Curie grant agreement No. 101034413.
  E.V. acknowledges support from the DISCOBOLO project funded by the Spanish Ministerio
  de Ciencia, Innovación y Universidades under grant PID2021-127289NB-I00. A.J.M.
  acknowledges support from the Swedish National Space Agency (Career grant 2023-00146).
  X.P.C. and M.M. acknowledge support from the Spanish Ministerio de Ciencia, Innovaciòn
  y Universidades under grants PID2021122842OB-C22 and PID2024-157964OB-C22; from
  the Xunta de Galicia and the European Union (FEDER Galicia 2021-2027 Program) Ref.
  ED431B 2024/21, ED431B 2024/02, and CITIC ED431G 2023/01. This work has made use
  of data from the European Space Agency (ESA) Gaia mission and processed by the Gaia
  Data Processing and Analysis Consortium (DPAC). Funding for the DPAC has been provided
  by national institutions, particularly the institutions participating in the Gaia
  Multilateral Agreement.
article_number: '146'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: X.
  full_name: Pérez-Couto, X.
  last_name: Pérez-Couto
- first_name: Santiago
  full_name: Torres Rodriguez, Santiago
  id: a8df4360-4328-11ee-8f1a-e502d0c83fc2
  last_name: Torres Rodriguez
  orcid: 0000-0002-3150-8988
- first_name: E.
  full_name: Villaver, E.
  last_name: Villaver
- first_name: A. J.
  full_name: Mustill, A. J.
  last_name: Mustill
- first_name: M.
  full_name: Manteiga, M.
  last_name: Manteiga
citation:
  ama: 'Pérez-Couto X, Torres Rodriguez S, Villaver E, Mustill AJ, Manteiga M. 3I/ATLAS:
    In search of the witnesses to its voyage. <i>The Astrophysical Journal</i>. 2026;1001(2).
    doi:<a href="https://doi.org/10.3847/1538-4357/ae56ff">10.3847/1538-4357/ae56ff</a>'
  apa: 'Pérez-Couto, X., Torres Rodriguez, S., Villaver, E., Mustill, A. J., &#38;
    Manteiga, M. (2026). 3I/ATLAS: In search of the witnesses to its voyage. <i>The
    Astrophysical Journal</i>. IOP Publishing. <a href="https://doi.org/10.3847/1538-4357/ae56ff">https://doi.org/10.3847/1538-4357/ae56ff</a>'
  chicago: 'Pérez-Couto, X., Santiago Torres Rodriguez, E. Villaver, A. J. Mustill,
    and M. Manteiga. “3I/ATLAS: In Search of the Witnesses to Its Voyage.” <i>The
    Astrophysical Journal</i>. IOP Publishing, 2026. <a href="https://doi.org/10.3847/1538-4357/ae56ff">https://doi.org/10.3847/1538-4357/ae56ff</a>.'
  ieee: 'X. Pérez-Couto, S. Torres Rodriguez, E. Villaver, A. J. Mustill, and M. Manteiga,
    “3I/ATLAS: In search of the witnesses to its voyage,” <i>The Astrophysical Journal</i>,
    vol. 1001, no. 2. IOP Publishing, 2026.'
  ista: 'Pérez-Couto X, Torres Rodriguez S, Villaver E, Mustill AJ, Manteiga M. 2026.
    3I/ATLAS: In search of the witnesses to its voyage. The Astrophysical Journal.
    1001(2), 146.'
  mla: 'Pérez-Couto, X., et al. “3I/ATLAS: In Search of the Witnesses to Its Voyage.”
    <i>The Astrophysical Journal</i>, vol. 1001, no. 2, 146, IOP Publishing, 2026,
    doi:<a href="https://doi.org/10.3847/1538-4357/ae56ff">10.3847/1538-4357/ae56ff</a>.'
  short: X. Pérez-Couto, S. Torres Rodriguez, E. Villaver, A.J. Mustill, M. Manteiga,
    The Astrophysical Journal 1001 (2026).
date_created: 2026-04-26T22:01:46Z
date_published: 2026-04-20T00:00:00Z
date_updated: 2026-04-28T13:08:39Z
day: '20'
ddc:
- '520'
department:
- _id: LiBu
doi: 10.3847/1538-4357/ae56ff
ec_funded: 1
external_id:
  arxiv:
  - '2509.07678'
file:
- access_level: open_access
  checksum: c3daf49261a9933c079854c38eec316f
  content_type: application/pdf
  creator: dernst
  date_created: 2026-04-28T13:06:00Z
  date_updated: 2026-04-28T13:06:00Z
  file_id: '21773'
  file_name: 2026_AstrophysicalJournal_PerezCouto.pdf
  file_size: 2905627
  relation: main_file
  success: 1
file_date_updated: 2026-04-28T13:06:00Z
has_accepted_license: '1'
intvolume: '      1001'
issue: '2'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
publication: The Astrophysical Journal
publication_identifier:
  eissn:
  - 1538-4357
  issn:
  - 0004-637X
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: '3I/ATLAS: In search of the witnesses to its voyage'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1001
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21761'
abstract:
- lang: eng
  text: Neural tube closure is a critical morphogenetic process in vertebrate development,
    and failure to close cranial regions such as the hindbrain neuropore (HNP) leads
    to severe congenital malformations. While mechanical forces such as actomyosin
    purse-string contraction and directional cell crawling have been implicated in
    driving HNP closure, how these forces organize local cell shape and motion to
    produce large-scale tissue remodeling remains poorly understood. Using live and
    fixed imaging of mouse embryos combined with cell-based biophysical modeling,
    we show that these force-generating mechanisms are insufficient to explain the
    reproducible patterns of cell elongation and nematic alignment observed at the
    HNP border. Instead, we show that local anisotropic stress and cytoskeletal organization
    are required to generate these patterns and promote midline cell motion. Our model
    captures key features of cell shape dynamics and emergent nematic order, which
    we confirm experimentally, including the alignment of actin fibers with cell shape
    and enhanced midline cell speed. Comparative analysis with chick embryos, which
    lack supracellular purse strings, supports a conserved link between tension generation
    and cellular patterning. These findings establish a physical framework connecting
    force generation, cell shape anisotropy, and tissue morphodynamics during epithelial
    gap closure.
acknowledgement: S.B. acknowledges support from the National Institutes of Health
  (NIH R35 GM143042) and the National Science Foundation (NSF MCB-2203601). G.L.G.
  acknowledges support from the Wellcome Trust (211112/Z/18/Z), the Royal Society
  (RG\R2\232082), and the Leverhulme Trust (RPG-2024-147). E.M. acknowledges support
  from European Union’s Horizon 2021 Marie Sklodowska-Curie grant agreement no. 101067028.
  F.P.-V. acknowledges support from the NOMIS foundation. The surface subtraction
  macro is courtesy of Dr. Dale Moulding and available on GitHub (https://github.com/DaleMoulding/Fiji-Macros).
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Fernanda L
  full_name: Perez Verdugo, Fernanda L
  id: 4ecec223-9070-11ef-a0a9-bc76077bea8d
  last_name: Perez Verdugo
- first_name: Eirini
  full_name: Maniou, Eirini
  last_name: Maniou
- first_name: Gabriel L.
  full_name: Galea, Gabriel L.
  last_name: Galea
- first_name: Shiladitya
  full_name: Banerjee, Shiladitya
  last_name: Banerjee
citation:
  ama: Perez Verdugo FL, Maniou E, Galea GL, Banerjee S. Mechanosensitive feedback
    organizes cell shape and motion during hindbrain neuropore morphogenesis. <i>Current
    Biology</i>. 2026;36(8):1903-1917.e5. doi:<a href="https://doi.org/10.1016/j.cub.2026.02.068">10.1016/j.cub.2026.02.068</a>
  apa: Perez Verdugo, F. L., Maniou, E., Galea, G. L., &#38; Banerjee, S. (2026).
    Mechanosensitive feedback organizes cell shape and motion during hindbrain neuropore
    morphogenesis. <i>Current Biology</i>. Elsevier. <a href="https://doi.org/10.1016/j.cub.2026.02.068">https://doi.org/10.1016/j.cub.2026.02.068</a>
  chicago: Perez Verdugo, Fernanda L, Eirini Maniou, Gabriel L. Galea, and Shiladitya
    Banerjee. “Mechanosensitive Feedback Organizes Cell Shape and Motion during Hindbrain
    Neuropore Morphogenesis.” <i>Current Biology</i>. Elsevier, 2026. <a href="https://doi.org/10.1016/j.cub.2026.02.068">https://doi.org/10.1016/j.cub.2026.02.068</a>.
  ieee: F. L. Perez Verdugo, E. Maniou, G. L. Galea, and S. Banerjee, “Mechanosensitive
    feedback organizes cell shape and motion during hindbrain neuropore morphogenesis,”
    <i>Current Biology</i>, vol. 36, no. 8. Elsevier, p. 1903–1917.e5, 2026.
  ista: Perez Verdugo FL, Maniou E, Galea GL, Banerjee S. 2026. Mechanosensitive feedback
    organizes cell shape and motion during hindbrain neuropore morphogenesis. Current
    Biology. 36(8), 1903–1917.e5.
  mla: Perez Verdugo, Fernanda L., et al. “Mechanosensitive Feedback Organizes Cell
    Shape and Motion during Hindbrain Neuropore Morphogenesis.” <i>Current Biology</i>,
    vol. 36, no. 8, Elsevier, 2026, p. 1903–1917.e5, doi:<a href="https://doi.org/10.1016/j.cub.2026.02.068">10.1016/j.cub.2026.02.068</a>.
  short: F.L. Perez Verdugo, E. Maniou, G.L. Galea, S. Banerjee, Current Biology 36
    (2026) 1903–1917.e5.
date_created: 2026-04-26T22:01:46Z
date_published: 2026-04-20T00:00:00Z
date_updated: 2026-04-28T13:15:42Z
day: '20'
ddc:
- '570'
department:
- _id: AnSa
doi: 10.1016/j.cub.2026.02.068
external_id:
  pmid:
  - '41881011'
file:
- access_level: open_access
  checksum: 80ae45457b4682c50c84f54de15aa9a8
  content_type: application/pdf
  creator: dernst
  date_created: 2026-04-28T13:13:40Z
  date_updated: 2026-04-28T13:13:40Z
  file_id: '21774'
  file_name: 2026_CurrentBiology_PerezVerdugo.pdf
  file_size: 13402043
  relation: main_file
  success: 1
file_date_updated: 2026-04-28T13:13:40Z
has_accepted_license: '1'
intvolume: '        36'
issue: '8'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '04'
oa: 1
oa_version: Published Version
page: 1903-1917.e5
pmid: 1
publication: Current Biology
publication_identifier:
  eissn:
  - 1879-0445
  issn:
  - 0960-9822
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mechanosensitive feedback organizes cell shape and motion during hindbrain
  neuropore morphogenesis
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 36
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '21763'
abstract:
- lang: eng
  text: Reactive oxygen species (ROS) have been implicated in multiple signaling processes
    in plants, but the underlying mechanisms and roles remain enigmatic. In this study,
    we developed a method of live imaging of apoplastic ROS at the root surface. Distinct
    signals, including auxin, extracellular adenosine triphosphate, and rapid alkalinization
    factor 1 peptide, induce cytosolic calcium transients and apoplastic ROS bursts.
    Genetic and optogenetic manipulations of Arabidopsis identified calcium transients
    as necessary and sufficient for ROS bursts through activation of reduced nicotinamide
    adenine dinucleotide phosphate (NADPH) oxidases RBOHC and RBOHF. Apoplastic ROS
    bursts are not required, but they do limit gravity-induced root bending. Root
    bending is sensed by the stretch-activated calcium channel MCA1, leading to NADPH
    oxidase activation. The resulting ROS production stiffens cell walls to facilitate
    soil penetration. Apoplastic ROS thus provides a means to balance tissue flexibility
    and stiffness to navigate soil.
acknowledged_ssus:
- _id: LifeSc
- _id: Bio
acknowledgement: "We gratefully acknowledge the Lab Support Facility (LSF) and the
  Imaging and Optics Facility (IOF) (both of ISTA) and the Hounsfield CT Facility
  (University of Nottingham) for support with imaging and the Growth Facility (IPMB)
  for plant cultivation. We thank M. Fendrych and his team for help with the microfluidics
  upgrades and J. Atkinson at the University of Nottingham MakerSpace for 3D printing
  of Arabidopsis mini-soil columns.\r\nThis project received funding from the European
  Research Council (ERC; 101142681 CYNIPS) and the Austrian Science Fund (FWF; P 37051-B).
  I.K. was cofunded by the European Union, Horizon Europe, project MOLIPEC, ID 101087030
  and CSF project 25-16449S. L.V. and B.K.P. acknowledge funding from UK Research
  and Innovation (UKRI) Frontiers Research (EP/Y036697/1). M.J.B. acknowledges funding
  from ERC SYNERGY (grant 101118769 HYDROSENSING). The study was partially supported
  by the Université Paris Cité, Idex ANR-18-IDEX-0001, funded by the French Government
  through its “Investments for the Future” program and also by the projects “Mecha-Nuc”
  ANR-20-CE13-0025-03 and “scEm-bryoMech” ANR-21-CE13-0046. P.D. acknowledges support
  by Human Frontier Science Program Organization grant 2022-RG107. P.V. acknowledges
  support provided by “Programme blanc” of the Graduate School BIOSPHERA, Université
  Paris-Saclay. Phytohormonal analysis was performed using the service laboratory
  funded by Toward Next GENeration Crops, reg. no. CZ.02.01.01/00/22_008/0004581 of
  the European Regional Development Fund (ERDF) program Johannes Amos Comenius. This
  research was funded in whole or in part by the Austrian Science Fund (P 37051-B)
  and UK Research and Innovation (EP/Y036697/1), cOAlition S organizations, and by
  the European Research Council (101142681 CYNIPS, 101118769 HYDROSENSING); as required,
  the author will make the Author Accepted Manuscript (AAM) version available under
  a CC BY public copyright license."
article_processing_charge: No
article_type: original
author:
- first_name: Ivan
  full_name: Kulich, Ivan
  id: 57a1567c-8314-11eb-9063-c9ddc3451a54
  last_name: Kulich
- first_name: Dmitrii
  full_name: Vladimirtsev, Dmitrii
  id: 60466724-5355-11ee-ae5a-fa55e8f99c3d
  last_name: Vladimirtsev
- first_name: Marek
  full_name: Randuch, Marek
  id: 6ac4636d-15b2-11ec-abd3-fb8df79972ae
  last_name: Randuch
- first_name: Shiqiang
  full_name: Gao, Shiqiang
  last_name: Gao
- first_name: Matteo
  full_name: Citterico, Matteo
  last_name: Citterico
- first_name: Kai R.
  full_name: Konrad, Kai R.
  last_name: Konrad
- first_name: Georg
  full_name: Nagel, Georg
  last_name: Nagel
- first_name: Michael
  full_name: Wrzaczek, Michael
  last_name: Wrzaczek
- first_name: Léa
  full_name: Cascaro, Léa
  last_name: Cascaro
- first_name: Pauline
  full_name: Vinet, Pauline
  last_name: Vinet
- first_name: Pauline
  full_name: Durand, Pauline
  last_name: Durand
- first_name: Atef
  full_name: Asnacios, Atef
  last_name: Asnacios
- first_name: Lokesh
  full_name: Verma, Lokesh
  last_name: Verma
- first_name: Malcolm J.
  full_name: Bennett, Malcolm J.
  last_name: Bennett
- first_name: Bipin K.
  full_name: Pandey, Bipin K.
  last_name: Pandey
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Kulich I, Vladimirtsev D, Randuch M, et al. Calcium-triggered apoplastic ROS
    bursts balance gravity and mechanical signals for soil navigation. <i>Science</i>.
    2026;392(6795):296-300. doi:<a href="https://doi.org/10.1126/science.adu8197">10.1126/science.adu8197</a>
  apa: Kulich, I., Vladimirtsev, D., Randuch, M., Gao, S., Citterico, M., Konrad,
    K. R., … Friml, J. (2026). Calcium-triggered apoplastic ROS bursts balance gravity
    and mechanical signals for soil navigation. <i>Science</i>. AAAS. <a href="https://doi.org/10.1126/science.adu8197">https://doi.org/10.1126/science.adu8197</a>
  chicago: Kulich, Ivan, Dmitrii Vladimirtsev, Marek Randuch, Shiqiang Gao, Matteo
    Citterico, Kai R. Konrad, Georg Nagel, et al. “Calcium-Triggered Apoplastic ROS
    Bursts Balance Gravity and Mechanical Signals for Soil Navigation.” <i>Science</i>.
    AAAS, 2026. <a href="https://doi.org/10.1126/science.adu8197">https://doi.org/10.1126/science.adu8197</a>.
  ieee: I. Kulich <i>et al.</i>, “Calcium-triggered apoplastic ROS bursts balance
    gravity and mechanical signals for soil navigation,” <i>Science</i>, vol. 392,
    no. 6795. AAAS, pp. 296–300, 2026.
  ista: Kulich I, Vladimirtsev D, Randuch M, Gao S, Citterico M, Konrad KR, Nagel
    G, Wrzaczek M, Cascaro L, Vinet P, Durand P, Asnacios A, Verma L, Bennett MJ,
    Pandey BK, Friml J. 2026. Calcium-triggered apoplastic ROS bursts balance gravity
    and mechanical signals for soil navigation. Science. 392(6795), 296–300.
  mla: Kulich, Ivan, et al. “Calcium-Triggered Apoplastic ROS Bursts Balance Gravity
    and Mechanical Signals for Soil Navigation.” <i>Science</i>, vol. 392, no. 6795,
    AAAS, 2026, pp. 296–300, doi:<a href="https://doi.org/10.1126/science.adu8197">10.1126/science.adu8197</a>.
  short: I. Kulich, D. Vladimirtsev, M. Randuch, S. Gao, M. Citterico, K.R. Konrad,
    G. Nagel, M. Wrzaczek, L. Cascaro, P. Vinet, P. Durand, A. Asnacios, L. Verma,
    M.J. Bennett, B.K. Pandey, J. Friml, Science 392 (2026) 296–300.
corr_author: '1'
date_created: 2026-04-26T22:01:47Z
date_published: 2026-04-16T00:00:00Z
date_updated: 2026-05-07T06:20:07Z
day: '16'
ddc:
- '580'
department:
- _id: JiFr
- _id: GradSch
doi: 10.1126/science.adu8197
external_id:
  pmid:
  - '41990180'
file:
- access_level: open_access
  checksum: eb5b29247832ecdc53c8146da0509bbe
  content_type: application/pdf
  creator: dernst
  date_created: 2026-05-07T05:54:43Z
  date_updated: 2026-05-07T05:54:43Z
  file_id: '21832'
  file_name: 2026_Science_Kulich_accepted.pdf
  file_size: 6150733
  relation: main_file
  success: 1
file_date_updated: 2026-05-07T05:54:43Z
has_accepted_license: '1'
intvolume: '       392'
issue: '6795'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Accepted Version
page: 296-300
pmid: 1
project:
- _id: 8f347782-16d5-11f0-9cad-8c19706ee739
  grant_number: '101142681'
  name: Cyclic nucleotides as second messengers in plants
- _id: 7bcece63-9f16-11ee-852c-ae94e099eeb6
  grant_number: P37051
  name: Guanylate cyclase activity of TIR1/AFBs auxin receptors
publication: Science
publication_identifier:
  eissn:
  - 1095-9203
  issn:
  - 0036-8075
publication_status: published
publisher: AAAS
quality_controlled: '1'
scopus_import: '1'
status: public
title: Calcium-triggered apoplastic ROS bursts balance gravity and mechanical signals
  for soil navigation
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 392
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21764'
abstract:
- lang: eng
  text: "Colloidal fluids can exhibit complex phase behavior and determining phase
    diagrams via experiments or computer simulations can be laborious. We demonstrate
    that the dispersion relation ω(k), obtained from dynamical density functional
    theory for the uniform density system, is a highly versatile tool for predicting
    where in the phase diagram complex crystals form. The sign of ω(k) determines
    whether density modes with wave number k grow or decay over time. We demonstrate
    the predictive power by investigating the complex phase behavior of particles
    interacting via core-shoulder pair potentials. With complementary Monte Carlo
    simulations, we show that regions of the phase diagram where ωðkÞ has one or several
    unstable (growing) wave numbers are also where crystalline phases occur. Going
    further, by tuning these\r\nunstable wave numbers via the interaction-potential
    and state-point parameters, we design systems with quasicrystals in the phase
    diagram. We identify a system with a certain shoulder range exhibiting at least
    ten different phases. Our general approach accelerates considerably the mapping
    of complex phase diagrams, crucial for the design of new materials."
acknowledgement: "The authors thank Ms. Katrin Muck for her guidance related to the
  use of HPC. The MC\r\ncomputer simulation results presented here were enabled via
  a generous share of CPU time, offered by the Vienna Scientific Cluster (VSC) under
  Project No. 71263. A. J. A. gratefully acknowledges support from the EPSRC under
  Grant No. EP/P015689/1. This research was funded in part by the Austrian Science
  Fund (FWF) [Grant DOI: 10.55776/PIN8759524], gratefully acknowledged by G. K ."
article_number: '148203'
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Michael
  full_name: Wassermair, Michael
  id: 23d132c4-4e98-11ef-b275-9e8d4cd8c917
  last_name: Wassermair
  orcid: 0009-0003-6339-4051
- first_name: Gerhard
  full_name: Kahl, Gerhard
  last_name: Kahl
- first_name: Roland
  full_name: Roth, Roland
  last_name: Roth
- first_name: Andrew J.
  full_name: Archer, Andrew J.
  last_name: Archer
citation:
  ama: Wassermair M, Kahl G, Roth R, Archer AJ. Navigating complex phase diagrams
    in soft matter systems. <i>Physical Review Letters</i>. 2026;136(14). doi:<a href="https://doi.org/10.1103/nbvt-fgjy">10.1103/nbvt-fgjy</a>
  apa: Wassermair, M., Kahl, G., Roth, R., &#38; Archer, A. J. (2026). Navigating
    complex phase diagrams in soft matter systems. <i>Physical Review Letters</i>.
    American Physical Society. <a href="https://doi.org/10.1103/nbvt-fgjy">https://doi.org/10.1103/nbvt-fgjy</a>
  chicago: Wassermair, Michael, Gerhard Kahl, Roland Roth, and Andrew J. Archer. “Navigating
    Complex Phase Diagrams in Soft Matter Systems.” <i>Physical Review Letters</i>.
    American Physical Society, 2026. <a href="https://doi.org/10.1103/nbvt-fgjy">https://doi.org/10.1103/nbvt-fgjy</a>.
  ieee: M. Wassermair, G. Kahl, R. Roth, and A. J. Archer, “Navigating complex phase
    diagrams in soft matter systems,” <i>Physical Review Letters</i>, vol. 136, no.
    14. American Physical Society, 2026.
  ista: Wassermair M, Kahl G, Roth R, Archer AJ. 2026. Navigating complex phase diagrams
    in soft matter systems. Physical Review Letters. 136(14), 148203.
  mla: Wassermair, Michael, et al. “Navigating Complex Phase Diagrams in Soft Matter
    Systems.” <i>Physical Review Letters</i>, vol. 136, no. 14, 148203, American Physical
    Society, 2026, doi:<a href="https://doi.org/10.1103/nbvt-fgjy">10.1103/nbvt-fgjy</a>.
  short: M. Wassermair, G. Kahl, R. Roth, A.J. Archer, Physical Review Letters 136
    (2026).
date_created: 2026-04-26T22:01:47Z
date_published: 2026-04-10T00:00:00Z
date_updated: 2026-04-28T07:03:48Z
day: '10'
ddc:
- '530'
department:
- _id: AnSa
- _id: GradSch
doi: 10.1103/nbvt-fgjy
external_id:
  arxiv:
  - '2603.18918'
file:
- access_level: open_access
  checksum: 8ffb139122a185fcddbe6a9c901a287c
  content_type: application/pdf
  creator: dernst
  date_created: 2026-04-28T06:58:40Z
  date_updated: 2026-04-28T06:58:40Z
  file_id: '21769'
  file_name: 2026_PhysicalReviewLetters_Wassermair.pdf
  file_size: 4336488
  relation: main_file
  success: 1
file_date_updated: 2026-04-28T06:58:40Z
has_accepted_license: '1'
intvolume: '       136'
issue: '14'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
publication: Physical Review Letters
publication_identifier:
  eissn:
  - 1079-7114
  issn:
  - 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Navigating complex phase diagrams in soft matter systems
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 136
year: '2026'
...
---
OA_type: closed access
_id: '21765'
abstract:
- lang: eng
  text: "Dielectric particles of the same material exchange electrical charge during
    collisions or sliding contacts, yet the underlying charge-exchange mechanism is
    still not understood. The fact that particles can become highly charged as a result
    of this effect has significant consequences for many settings, both in nature
    and industry, such as thunderstorms, volcanic eruptions, particle aggregation
    during meteorite and planet formation, and the clogging of industrial granular
    systems. Toward understanding these systems, great efforts have been made to develop
    precise in situ measurements for particle charge, e.g., to determine ensemble
    charge distributions or measure exchange during individual contacts. Here, we
    present experimental results concerning the particle size scaling of the stationary-state
    charge distributions of oxide particles in the sub-millimeter range. We measure
    the charge distributions for large ensembles of monodisperse ZrO2:SiO2 composite
    spheres, ranging from 172 to 545µ⁢m in diameter. These distributions are non-Gaussian
    and collapse to a single master curve when plotted as functions of the surface
    charge density Σ=\U0001D45E/4⁢\U0001D70B⁢\U0001D4452. X-ray fluorescence and atomic
    force microscopy measurements show that the differences in the measured charge
    distributions are not due to variations in chemical composition or surface roughness,
    but rather to size alone. Our findings provide constraints on microscopic models
    for charge exchange, namely that they should lead to steady-state distributions
    that are non-Gaussian and scale in a specific way with particle size."
acknowledgement: This research was supported by ANID Grants QUIMAL No. 160001, FONDECYT
  No. 1221597, and FONDEQUIP No. EQM190177. The authors thank Rodrigo Espinoza for
  the EDS-SEM measurements and Domingo Jullian for fruitful discussions. We also acknowledge
  the technical assistance of Ricardo Silva and Andrés Espinosa at DFI, FCFM, Universidad
  de Chile.
article_number: '045604'
article_processing_charge: No
article_type: original
author:
- first_name: Macarena
  full_name: Lara, Macarena
  last_name: Lara
- first_name: Marcos
  full_name: Flores, Marcos
  last_name: Flores
- first_name: Gustavo
  full_name: Castillo, Gustavo
  last_name: Castillo
- first_name: Santiago
  full_name: Tassara, Santiago
  last_name: Tassara
- first_name: Scott R
  full_name: Waitukaitis, Scott R
  id: 3A1FFC16-F248-11E8-B48F-1D18A9856A87
  last_name: Waitukaitis
  orcid: 0000-0002-2299-3176
- first_name: Nicolás
  full_name: Mujica, Nicolás
  last_name: Mujica
citation:
  ama: Lara M, Flores M, Castillo G, Tassara S, Waitukaitis SR, Mujica N. Particle
    size scaling of non-Gaussian granular charge distributions. <i>Physical Review
    Materials</i>. 2026;10(4). doi:<a href="https://doi.org/10.1103/qw6t-xqdw">10.1103/qw6t-xqdw</a>
  apa: Lara, M., Flores, M., Castillo, G., Tassara, S., Waitukaitis, S. R., &#38;
    Mujica, N. (2026). Particle size scaling of non-Gaussian granular charge distributions.
    <i>Physical Review Materials</i>. American Physical Society. <a href="https://doi.org/10.1103/qw6t-xqdw">https://doi.org/10.1103/qw6t-xqdw</a>
  chicago: Lara, Macarena, Marcos Flores, Gustavo Castillo, Santiago Tassara, Scott
    R Waitukaitis, and Nicolás Mujica. “Particle Size Scaling of Non-Gaussian Granular
    Charge Distributions.” <i>Physical Review Materials</i>. American Physical Society,
    2026. <a href="https://doi.org/10.1103/qw6t-xqdw">https://doi.org/10.1103/qw6t-xqdw</a>.
  ieee: M. Lara, M. Flores, G. Castillo, S. Tassara, S. R. Waitukaitis, and N. Mujica,
    “Particle size scaling of non-Gaussian granular charge distributions,” <i>Physical
    Review Materials</i>, vol. 10, no. 4. American Physical Society, 2026.
  ista: Lara M, Flores M, Castillo G, Tassara S, Waitukaitis SR, Mujica N. 2026. Particle
    size scaling of non-Gaussian granular charge distributions. Physical Review Materials.
    10(4), 045604.
  mla: Lara, Macarena, et al. “Particle Size Scaling of Non-Gaussian Granular Charge
    Distributions.” <i>Physical Review Materials</i>, vol. 10, no. 4, 045604, American
    Physical Society, 2026, doi:<a href="https://doi.org/10.1103/qw6t-xqdw">10.1103/qw6t-xqdw</a>.
  short: M. Lara, M. Flores, G. Castillo, S. Tassara, S.R. Waitukaitis, N. Mujica,
    Physical Review Materials 10 (2026).
date_created: 2026-04-26T22:01:47Z
date_published: 2026-04-01T00:00:00Z
date_updated: 2026-04-28T07:13:56Z
day: '01'
department:
- _id: ScWa
doi: 10.1103/qw6t-xqdw
intvolume: '        10'
issue: '4'
language:
- iso: eng
month: '04'
oa_version: None
publication: Physical Review Materials
publication_identifier:
  eissn:
  - 2475-9953
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Particle size scaling of non-Gaussian granular charge distributions
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21766'
abstract:
- lang: eng
  text: We provide a new characterisation of the decades old open problem of extending
    bilipschitz mappings given on a Euclidean separated net. In particular, this allows
    for the complete positive solution of the open problem in dimension two. Along
    the way, we develop a set of tools for bilipschitz extensions of mappings between
    subsets of Euclidean spaces.
acknowledgement: "The present work developed from a research visit of M.D. to V.K.
  at IST Austria, funded by\r\na London Mathematical Society Research in Pairs grant.
  This work was done while V.K. was fully funded by the Austria Science Fund (FWF)
  [M 3100-N]."
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Michael
  full_name: Dymond, Michael
  last_name: Dymond
- first_name: Vojtech
  full_name: Kaluza, Vojtech
  id: 21AE5134-9EAC-11EA-BEA2-D7BD3DDC885E
  last_name: Kaluza
  orcid: 0000-0002-2512-8698
citation:
  ama: Dymond M, Kaluza V. Extending bilipschitz mappings between separated nets.
    <i>Annales Fennici Mathematici</i>. 2026;51(1):237-260. doi:<a href="https://doi.org/10.54330/afm.181562">10.54330/afm.181562</a>
  apa: Dymond, M., &#38; Kaluza, V. (2026). Extending bilipschitz mappings between
    separated nets. <i>Annales Fennici Mathematici</i>. Finnish Mathematical Society.
    <a href="https://doi.org/10.54330/afm.181562">https://doi.org/10.54330/afm.181562</a>
  chicago: Dymond, Michael, and Vojtech Kaluza. “Extending Bilipschitz Mappings between
    Separated Nets.” <i>Annales Fennici Mathematici</i>. Finnish Mathematical Society,
    2026. <a href="https://doi.org/10.54330/afm.181562">https://doi.org/10.54330/afm.181562</a>.
  ieee: M. Dymond and V. Kaluza, “Extending bilipschitz mappings between separated
    nets,” <i>Annales Fennici Mathematici</i>, vol. 51, no. 1. Finnish Mathematical
    Society, pp. 237–260, 2026.
  ista: Dymond M, Kaluza V. 2026. Extending bilipschitz mappings between separated
    nets. Annales Fennici Mathematici. 51(1), 237–260.
  mla: Dymond, Michael, and Vojtech Kaluza. “Extending Bilipschitz Mappings between
    Separated Nets.” <i>Annales Fennici Mathematici</i>, vol. 51, no. 1, Finnish Mathematical
    Society, 2026, pp. 237–60, doi:<a href="https://doi.org/10.54330/afm.181562">10.54330/afm.181562</a>.
  short: M. Dymond, V. Kaluza, Annales Fennici Mathematici 51 (2026) 237–260.
corr_author: '1'
date_created: 2026-04-26T22:01:47Z
date_published: 2026-04-17T00:00:00Z
date_updated: 2026-04-28T12:06:00Z
day: '17'
ddc:
- '510'
department:
- _id: UlWa
doi: 10.54330/afm.181562
external_id:
  arxiv:
  - '2507.22007'
file:
- access_level: open_access
  checksum: 442023926a3803d5d6ca8db8dbc4af1c
  content_type: application/pdf
  creator: dernst
  date_created: 2026-04-28T12:03:13Z
  date_updated: 2026-04-28T12:03:13Z
  file_id: '21772'
  file_name: 2026_AnnalesFenniciMath_Dymond.pdf
  file_size: 342082
  relation: main_file
  success: 1
file_date_updated: 2026-04-28T12:03:13Z
has_accepted_license: '1'
intvolume: '        51'
issue: '1'
keyword:
- Lipschitz
- bilipschitz
- extension
- separated net.
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/4.0/
month: '04'
oa: 1
oa_version: Published Version
page: 237-260
project:
- _id: fc35eaa2-9c52-11eb-aca3-88501ab155e9
  grant_number: M03100
  name: Spectra and topology of graphs and of simplicial complexes
publication: Annales Fennici Mathematici
publication_identifier:
  eissn:
  - 2737-114X
  issn:
  - 2737-0690
publication_status: published
publisher: Finnish Mathematical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Extending bilipschitz mappings between separated nets
tmp:
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  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 51
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21767'
abstract:
- lang: eng
  text: 'The involvement of non-scientific staff in discussions about animal welfare
    and scientific quality is essential for biomedical research progress. In this
    study, we developed a survey to collect the self-perception of animal care staff
    (ACS) and laboratory technicians about their involvement in scientific planning
    and conduct. Participants were contacted to complete an anonymous online questionnaire.
    We obtained 850 responses, mainly from Europe: 564 from ACS and 286 from laboratory
    technicians. Job satisfaction was assessed as positive by ACS and laboratory technicians
    despite the low frequency of culture of care activities and mental health meetings.
    Both groups expressed their desire to be trained in research planning and conduct;
    however, regular training was not reported. In addition, the inability to act
    on animal welfare concerns owing to experimental reasons was reported by both
    groups. Over half of the participants felt valued and appreciated by the lead
    scientists or animal facility manager; however, it is not clear how they are acknowledged,
    as their names on the authors list or in the manuscript acknowledgments are barely
    included. Our results indicated that involvement of ACS and laboratory technicians
    in planning and conducting studies would improve their understanding of how experiments
    are done, and therefore communication processes, work satisfaction, animal welfare,
    and scientific quality. Finally, we provided recommendations to improve the engagement
    of ACS and laboratory technicians in discussions about animal research planning
    and conduct.'
- lang: fre
  text: 'La participation de personnel non-scientifique aux discussions sur le bien-être
    animal et la qualité scientifique est essentielle aux progrès la recherche biomédicale.
    Dans cette étude, nous avons développé une enquête pour recueillir l''auto-perception
    du personnel chargé des soins prodigués aux animaux (PCSA) et des techniciens
    de laboratoire (TL) sur leur implication dans la planification et la conduite
    scientifiques. Les participants ont été contactés pour remplir un questionnaire
    anonyme en ligne. Nous avons obtenu 850 réponses, principalement en Europe : 564
    provenant de PCSA et 286 de TL. La satisfaction au travail a été évaluée comme
    positive par le PCSA et les TL malgré la faible fréquence d’activités sur la culture
    des soins et de réunions concernant la santé mentale. Bien que les deux groupes
    aient exprimé leur désir d''être formés à la planification et à la conduite de
    la recherche, aucune formation réelle régulière n''a été signalée. De plus, l''incapacité
    d''agir sur les préoccupations relatives au bien-être animal pour des raisons
    expérimentales a été signalée par les deux groupes. Plus de la moitié des participants
    se sont sentis valorisés et appréciés par les scientifiques principaux ou le gestionnaire
    de l’installation animale mais on ne sait pas clairement comment ils sont reconnus,
    car leurs noms sur la liste des auteurs ou dans les remerciements sont à peine
    inclus dans la documentation. Nos résultats ont indiqué que la participation du
    PCSA et des TL à la planification et à la conduite des études améliorerait leur
    compréhension de la façon dont les expériences sont effectuées et, par conséquent,
    les processus de communication, leur satisfaction au travail ainsi que le bien-être
    animal et la qualité scientifique. Enfin, nous avons formulé des recommandations
    pour améliorer la participation du PCSA et des TL aux discussions sur la planification
    et la conduite de la recherche animale.'
- lang: ger
  text: 'Die Einbeziehung von nichtwissenschaftlichem Personal in Diskussionen über
    Tierschutz und wissenschaftliche Qualität ist für Fortschritte in biomedizinischer
    Forschung von entscheidender Bedeutung. In dieser Studie haben wir eine Umfrage
    entwickelt, um die Selbsteinschätzung von Tierpflegern (ACS) und Labortechnikern
    (LT) hinsichtlich ihrer Beteiligung an der wissenschaftlichen Planung und Durchführung
    zu erfassen. Die Teilnehmer wurden gebeten, einen anonymen Online-Fragebogen auszufüllen.
    Wir erhielten 850 Rückmeldungen, hauptsächlich aus Europa: 564 von ACS und 286
    von LT. Die Arbeitszufriedenheit wurde von ACS und LT trotz der geringen Häufigkeit
    von Pflegeaktivitäten und Treffen zum Thema psychische Gesundheit als positiv
    bewertet. Beide Gruppen äußerten den Wunsch, in der Forschungsplanung und -durchführung
    geschult zu werden, doch regelmäßig stattfindende Schulungen wurden nicht berichtet.
    Außerdem wurde von beiden Gruppen vermeldet, dass sie aus versuchstechnischen
    Gründen nicht in der Lage waren, auf Tierschutzbedenken zu reagieren. Über die
    Hälfte der Teilnehmer fühlte sich von den leitenden Wissenschaftlern oder dem
    Leiter der Tierhaltungseinrichtung geschätzt und anerkannt; es ist jedoch unklar,
    inwiefern sie wirklich gewürdigt werden, da ihre Namen kaum in der Autorenliste
    oder in den Danksagungen des Manuskripts aufgeführt sind. Unsere Ergebnisse deuteten
    darauf hin, dass die Einbeziehung von ACS und LT in die Planung und Durchführung
    von Studien ihr Verständnis für die Durchführung von Experimenten verbessern würde
    – und damit auch Kommunikationsprozesse, Arbeitszufriedenheit, Tierwohl und wissenschaftliche
    Qualität. Abschließend gaben wir Empfehlungen zur Verbesserung der Einbeziehung
    von ACS und LT in Diskussionen über die Planung und Durchführung von Tierversuchen.'
- lang: spa
  text: 'La participación del personal no científico en los debates sobre el bienestar
    animal y la calidad científica es fundamental para el avance de la investigación
    biomédica. En este estudio, desarrollamos una encuesta para recoger la autopercepción
    del personal encargado del cuidado de los animales (ACS) y de los técnicos de
    laboratorio (LT) sobre su implicación en la planificación y la realización científicas.
    Se contactó con los participantes para que cumplimentaran un cuestionario anónimo
    en línea. Obtuvimos 850 respuestas, principalmente de Europa: 564 de ACS y 286
    de LT. La satisfacción laboral fue evaluada como positiva por ACS y técnicos de
    laboratorio a pesar de la baja frecuencia de actividades de cultura del cuidado
    y reuniones sobre bienestar mental. Ambos grupos expresaron su deseo de recibir
    formación en planificación y realización de investigaciones, sin embargo, no se
    informó sobre una formación regular. Asimismo, ambos grupos señalaron la incapacidad
    de actuar ante las preocupaciones sobre el bienestar animal por motivos experimentales.
    Más de la mitad de los participantes se sintieron valorados y apreciados por los
    científicos principales o el responsable de las instalaciones de animales; sin
    embargo, no está claro cómo se les reconoce, ya que apenas se incluyen sus nombres
    en la lista de autores o en los agradecimientos del manuscrito. Nuestros resultados
    indicaron que la participación de los ACS y los LT en la planificación y realización
    de los estudios mejoraría su comprensión de cómo se hacen los experimentos y,
    por tanto, los procesos de comunicación, la satisfacción laboral, el bienestar
    animal y la calidad científica. Finalmente, proporcionamos recomendaciones para
    mejorar el compromiso de la AEC y la LT en los debates sobre la planificación
    y la realización de investigaciones con animales.'
acknowledgement: "We deeply acknowledge all the animal care staff and laboratory technicians
  who participated in this study! We acknowledge Working Groups 1 and 4 from COST
  Action IMPROVE (“3Rs concepts to improve the quality of biomedical science”), CA21139,
  supported by COST (European Cooperation in Science and Technology) for their feedback
  and support. We also acknowledge Aoife Milford for her comments and contributions
  to the final draft of the manuscript.\r\nThis publication was based on work from
  the COST Action IMPROVE (“3Rs concepts to improve the quality of biomedical science”),
  CA21139, supported by COST (European Cooperation in Science and Technology)."
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Fernando
  full_name: Gonzalez-Uarquin, Fernando
  last_name: Gonzalez-Uarquin
- first_name: Paulin
  full_name: Jirkof, Paulin
  last_name: Jirkof
- first_name: Bettina
  full_name: Bert, Bettina
  last_name: Bert
- first_name: Penny
  full_name: Hawkins, Penny
  last_name: Hawkins
- first_name: Ljupco
  full_name: Angelovski, Ljupco
  last_name: Angelovski
- first_name: Jan
  full_name: Baumgart, Jan
  last_name: Baumgart
- first_name: Nadine
  full_name: Baumgart, Nadine
  last_name: Baumgart
- first_name: Özge S.
  full_name: Cevik, Özge S.
  last_name: Cevik
- first_name: Nuno H.
  full_name: Franco, Nuno H.
  last_name: Franco
- first_name: Erdal
  full_name: Horata, Erdal
  last_name: Horata
- first_name: Rohish
  full_name: Kaura, Rohish
  last_name: Kaura
- first_name: Winfried
  full_name: Neuhaus, Winfried
  last_name: Neuhaus
- first_name: Brigida
  full_name: Riso, Brigida
  last_name: Riso
- first_name: Adrian J.
  full_name: Smith, Adrian J.
  last_name: Smith
- first_name: Athanassia
  full_name: Sotiropoulos, Athanassia
  last_name: Sotiropoulos
- first_name: Augusto
  full_name: Vitale, Augusto
  last_name: Vitale
- first_name: Sophie
  full_name: Schober, Sophie
  id: 80b0a0ef-4b9f-11ec-b119-8d9d94c4a1d8
  last_name: Schober
citation:
  ama: 'Gonzalez-Uarquin F, Jirkof P, Bert B, et al. Building bridges: Involvement
    of animal care staff and laboratory technicians in experimental planning and conduct
    of animal studies for better job satisfaction and science. <i>Laboratory Animals</i>.
    2026. doi:<a href="https://doi.org/10.1177/00236772251400976">10.1177/00236772251400976</a>'
  apa: 'Gonzalez-Uarquin, F., Jirkof, P., Bert, B., Hawkins, P., Angelovski, L., Baumgart,
    J., … Schober, S. (2026). Building bridges: Involvement of animal care staff and
    laboratory technicians in experimental planning and conduct of animal studies
    for better job satisfaction and science. <i>Laboratory Animals</i>. SAGE Publications.
    <a href="https://doi.org/10.1177/00236772251400976">https://doi.org/10.1177/00236772251400976</a>'
  chicago: 'Gonzalez-Uarquin, Fernando, Paulin Jirkof, Bettina Bert, Penny Hawkins,
    Ljupco Angelovski, Jan Baumgart, Nadine Baumgart, et al. “Building Bridges: Involvement
    of Animal Care Staff and Laboratory Technicians in Experimental Planning and Conduct
    of Animal Studies for Better Job Satisfaction and Science.” <i>Laboratory Animals</i>.
    SAGE Publications, 2026. <a href="https://doi.org/10.1177/00236772251400976">https://doi.org/10.1177/00236772251400976</a>.'
  ieee: 'F. Gonzalez-Uarquin <i>et al.</i>, “Building bridges: Involvement of animal
    care staff and laboratory technicians in experimental planning and conduct of
    animal studies for better job satisfaction and science,” <i>Laboratory Animals</i>.
    SAGE Publications, 2026.'
  ista: 'Gonzalez-Uarquin F, Jirkof P, Bert B, Hawkins P, Angelovski L, Baumgart J,
    Baumgart N, Cevik ÖS, Franco NH, Horata E, Kaura R, Neuhaus W, Riso B, Smith AJ,
    Sotiropoulos A, Vitale A, Schober S. 2026. Building bridges: Involvement of animal
    care staff and laboratory technicians in experimental planning and conduct of
    animal studies for better job satisfaction and science. Laboratory Animals.'
  mla: 'Gonzalez-Uarquin, Fernando, et al. “Building Bridges: Involvement of Animal
    Care Staff and Laboratory Technicians in Experimental Planning and Conduct of
    Animal Studies for Better Job Satisfaction and Science.” <i>Laboratory Animals</i>,
    SAGE Publications, 2026, doi:<a href="https://doi.org/10.1177/00236772251400976">10.1177/00236772251400976</a>.'
  short: F. Gonzalez-Uarquin, P. Jirkof, B. Bert, P. Hawkins, L. Angelovski, J. Baumgart,
    N. Baumgart, Ö.S. Cevik, N.H. Franco, E. Horata, R. Kaura, W. Neuhaus, B. Riso,
    A.J. Smith, A. Sotiropoulos, A. Vitale, S. Schober, Laboratory Animals (2026).
date_created: 2026-04-26T22:01:47Z
date_published: 2026-04-14T00:00:00Z
date_updated: 2026-06-18T08:33:36Z
day: '14'
ddc:
- '570'
department:
- _id: PreCl
doi: 10.1177/00236772251400976
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1177/00236772251400976
month: '04'
oa: 1
oa_version: Published Version
publication: Laboratory Animals
publication_identifier:
  eissn:
  - 1758-1117
  issn:
  - 0023-6772
publication_status: epub_ahead
publisher: SAGE Publications
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Building bridges: Involvement of animal care staff and laboratory technicians
  in experimental planning and conduct of animal studies for better job satisfaction
  and science'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21776'
abstract:
- lang: eng
  text: Pyridyl motifs equipped with N-substituents can be powerful ligands for catalysis,
    yet their broader adoption is limited by the lack of a practical method to prepare
    these scaffolds. We report a modular, robust, and versatile Buchwald–Hartwig amination
    protocol that enables the rapid synthesis of bipyridine, phenanthroline, terpyridine,
    and pybox ligands bearing dialkylamine, diarylamine, and heteroaromatic N-substituents.
    These conditions streamline ligand library synthesis and will facilitate systematic
    studies in catalysis and related applications.
acknowledged_ssus:
- _id: LifeSc
- _id: MassSpec
- _id: NMR
- _id: M-Shop
acknowledgement: We gratefully acknowledge ISTA for generous financial support. B.P.
  acknowledges the Austrian Science Fund (PAT 1250924) and the ACS GCI Pharmaceutical
  Roundtable for funding; T.P.Y acknowledges the NSF(CHE-2349003) for financial support.
  This research was supported by the Scientific Service Units (SSU) of ISTA through
  resources provided by the Lab Support Facility, Mass Spec Facility, NMR facility,
  and the Miba Machine Shop. We specifically thank Aikaterina Paraskevopoulou for
  HRMS measurements and Jan Pecak for support with ICP-OES experi-ments. NMR facilities
  at UW−Madison were supported by the NSF(CHE-1048642) and a generous gift from Paul
  J. and Margaret M. Bender. Open Access funding provided by Institute of Science
  and Technology Austria/KEMÖ. This study was supported by Austrian Science Fund (PAT
  1250924), ACSGCI Pharmaceutical Roundtable, and National Science Foundation(CHE-2349003)
  and (CHE-1048642).
article_number: e70417
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Adam
  full_name: Petrik, Adam
  id: e273d403-329f-11ee-a353-8c34c056f8ed
  last_name: Petrik
- first_name: Aleksander
  full_name: Bena, Aleksander
  id: 4197c39e-e8ec-11ed-86cb-afed934cd664
  last_name: Bena
- first_name: Haralds
  full_name: Baunis, Haralds
  id: 2eea55ec-e8ec-11ed-86cb-d9c76787acfe
  last_name: Baunis
- first_name: Riley M.
  full_name: Kelch, Riley M.
  last_name: Kelch
- first_name: Tehshik P.
  full_name: Yoon, Tehshik P.
  last_name: Yoon
- first_name: Bartholomäus
  full_name: Pieber, Bartholomäus
  id: 93e5e5b2-0da6-11ed-8a41-af589a024726
  last_name: Pieber
  orcid: 0000-0001-8689-388X
citation:
  ama: Petrik A, Bena A, Baunis H, Kelch RM, Yoon TP, Pieber B. Facile access to N-substituted
    pyridyl ligands. <i>Advanced Synthesis &#38; Catalysis</i>. 2026;368(9). doi:<a
    href="https://doi.org/10.1002/adsc.70417">10.1002/adsc.70417</a>
  apa: Petrik, A., Bena, A., Baunis, H., Kelch, R. M., Yoon, T. P., &#38; Pieber,
    B. (2026). Facile access to N-substituted pyridyl ligands. <i>Advanced Synthesis
    &#38; Catalysis</i>. Wiley. <a href="https://doi.org/10.1002/adsc.70417">https://doi.org/10.1002/adsc.70417</a>
  chicago: Petrik, Adam, Aleksander Bena, Haralds Baunis, Riley M. Kelch, Tehshik
    P. Yoon, and Bartholomäus Pieber. “Facile Access to N-Substituted Pyridyl Ligands.”
    <i>Advanced Synthesis &#38; Catalysis</i>. Wiley, 2026. <a href="https://doi.org/10.1002/adsc.70417">https://doi.org/10.1002/adsc.70417</a>.
  ieee: A. Petrik, A. Bena, H. Baunis, R. M. Kelch, T. P. Yoon, and B. Pieber, “Facile
    access to N-substituted pyridyl ligands,” <i>Advanced Synthesis &#38; Catalysis</i>,
    vol. 368, no. 9. Wiley, 2026.
  ista: Petrik A, Bena A, Baunis H, Kelch RM, Yoon TP, Pieber B. 2026. Facile access
    to N-substituted pyridyl ligands. Advanced Synthesis &#38; Catalysis. 368(9),
    e70417.
  mla: Petrik, Adam, et al. “Facile Access to N-Substituted Pyridyl Ligands.” <i>Advanced
    Synthesis &#38; Catalysis</i>, vol. 368, no. 9, e70417, Wiley, 2026, doi:<a href="https://doi.org/10.1002/adsc.70417">10.1002/adsc.70417</a>.
  short: A. Petrik, A. Bena, H. Baunis, R.M. Kelch, T.P. Yoon, B. Pieber, Advanced
    Synthesis &#38; Catalysis 368 (2026).
corr_author: '1'
date_created: 2026-05-03T22:01:36Z
date_published: 2026-05-05T00:00:00Z
date_updated: 2026-05-07T07:33:33Z
day: '05'
ddc:
- '540'
department:
- _id: BaPi
- _id: GradSch
doi: 10.1002/adsc.70417
file:
- access_level: open_access
  checksum: afe9752977898642c903abdc70b4a283
  content_type: application/pdf
  creator: dernst
  date_created: 2026-05-07T07:29:24Z
  date_updated: 2026-05-07T07:29:24Z
  file_id: '21833'
  file_name: 2026_AdvSynthCatal_Petrik.pdf
  file_size: 437184
  relation: main_file
  success: 1
file_date_updated: 2026-05-07T07:29:24Z
has_accepted_license: '1'
intvolume: '       368'
issue: '9'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
project:
- _id: 8f1d607d-16d5-11f0-9cad-ab453295ba5e
  grant_number: PAT 1250924
  name: Photoactive ligands for transformative nickel catalysis
publication: Advanced Synthesis & Catalysis
publication_identifier:
  eissn:
  - 1615-4169
  issn:
  - 1615-4150
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Facile access to N-substituted pyridyl ligands
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 368
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21778'
abstract:
- lang: eng
  text: "We prove that every \U0001D43F-bilipschitz mapping ℤ 2 → ℝ2 canbe extended
    to a \U0001D436(\U0001D43F)-bilipschitz mapping ℝ2 → ℝ2,and we provide a polynomial
    upper bound for \U0001D436(\U0001D43F).Moreover, we extend the result to every
    separated netin ℝ2 instead of ℤ 2, with the upper bound gaininga polynomial dependence
    on the separation and netconstants associated to the given separated net. Thisanswers
    an Oberwolfach question of Navas from 2015and is also a positive solution of the
    two-dimensionalform of a decades old open (in all dimensions at leasttwo) problem
    due to Alestalo Trotsenko and Väisälä."
acknowledgement: The authors wish to thank Professor Leonid Kovalev for a valuable
  observation on the first versionof this work, which led to improved estimates and
  cleaner proofs in Section 6. The present workdeveloped from a research visit of
  Michael Dymond to Vojtěch Kaluža at IST Austria, funded by aLondon Mathematical
  Society Research in Pairs grant. This work was done whilst Vojtěch Kalužawas fully
  funded by the Austria Science Fund (FWF) [M 3100-N].
article_number: e70540
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Michael
  full_name: Dymond, Michael
  last_name: Dymond
- first_name: Vojtech
  full_name: Kaluza, Vojtech
  id: 21AE5134-9EAC-11EA-BEA2-D7BD3DDC885E
  last_name: Kaluza
  orcid: 0000-0002-2512-8698
citation:
  ama: Dymond M, Kaluza V. Planar bilipschitz extension from separated nets. <i>Journal
    of the London Mathematical Society</i>. 2026;113(4). doi:<a href="https://doi.org/10.1112/jlms.70540">10.1112/jlms.70540</a>
  apa: Dymond, M., &#38; Kaluza, V. (2026). Planar bilipschitz extension from separated
    nets. <i>Journal of the London Mathematical Society</i>. Wiley. <a href="https://doi.org/10.1112/jlms.70540">https://doi.org/10.1112/jlms.70540</a>
  chicago: Dymond, Michael, and Vojtech Kaluza. “Planar Bilipschitz Extension from
    Separated Nets.” <i>Journal of the London Mathematical Society</i>. Wiley, 2026.
    <a href="https://doi.org/10.1112/jlms.70540">https://doi.org/10.1112/jlms.70540</a>.
  ieee: M. Dymond and V. Kaluza, “Planar bilipschitz extension from separated nets,”
    <i>Journal of the London Mathematical Society</i>, vol. 113, no. 4. Wiley, 2026.
  ista: Dymond M, Kaluza V. 2026. Planar bilipschitz extension from separated nets.
    Journal of the London Mathematical Society. 113(4), e70540.
  mla: Dymond, Michael, and Vojtech Kaluza. “Planar Bilipschitz Extension from Separated
    Nets.” <i>Journal of the London Mathematical Society</i>, vol. 113, no. 4, e70540,
    Wiley, 2026, doi:<a href="https://doi.org/10.1112/jlms.70540">10.1112/jlms.70540</a>.
  short: M. Dymond, V. Kaluza, Journal of the London Mathematical Society 113 (2026).
date_created: 2026-05-03T22:01:37Z
date_published: 2026-04-01T00:00:00Z
date_updated: 2026-05-07T08:29:18Z
day: '01'
ddc:
- '510'
department:
- _id: UlWa
doi: 10.1112/jlms.70540
external_id:
  arxiv:
  - '2410.22294'
file:
- access_level: open_access
  checksum: 6dbfc7134f732d17c5c8467843a73e90
  content_type: application/pdf
  creator: dernst
  date_created: 2026-05-07T08:27:43Z
  date_updated: 2026-05-07T08:27:43Z
  file_id: '21836'
  file_name: 2026_JourLondonMathSoc_Dymond.pdf
  file_size: 617569
  relation: main_file
  success: 1
file_date_updated: 2026-05-07T08:27:43Z
has_accepted_license: '1'
intvolume: '       113'
issue: '4'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
project:
- _id: fc35eaa2-9c52-11eb-aca3-88501ab155e9
  grant_number: M03100
  name: Spectra and topology of graphs and of simplicial complexes
publication: Journal of the London Mathematical Society
publication_identifier:
  eissn:
  - 1469-7750
  issn:
  - 0024-6107
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Planar bilipschitz extension from separated nets
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 113
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '21779'
abstract:
- lang: eng
  text: Acidomycin is an anti-mycobacterial antibiotic with a unique mode of action,
    targeting the biotin biosynthesis pathway. Despite being highly active against
    mycobacteria in vitro, its development as an anti-tubercular agent has been hindered
    due to suboptimal pharmacokinetics. Engineering of the acidomycin biosynthesis
    may yield new analogues with improved pharmacological properties. Here, we describe
    the identification of the acidomycin biosynthetic gene cluster (BGC) in a Streptomyces
    bacterium isolated from the rhizosphere of Edelweiss. Notably, the acidomycin
    BGC is located in proximity to the genes for the biosynthesis of stravidins, secondary
    metabolites targeting a different enzyme in the biotin biosynthesis pathway, and
    two genes for streptavidins, proteins that strongly bind and sequester biotin.
    The identity of the acidomycin BGC was confirmed via both gene knock-out and heterologous
    expression, which suggested that the fatty acid required for the formation of
    acidomycin's acyl chain is most likely scavenged from the biotin biosynthesis
    pathway. CRISPR/Cas9-assisted knock-out of the cytochrome P450-encoding gene in
    the acidomycin BGC resulted in a significant decrease in its yield but did not
    abrogate the biosynthesis completely.
acknowledgement: This work was supported by the University of Vienna. The authors
  thank Anna Fabisikova from the Mass Spectrometry Centre and the team of the NMR
  Centre (both of the Faculty of Chemistry, University of Vienna and members of the
  Vienna Life Science Instruments) for assistance with data acquisition. Open Access
  funding provided by Universitat Wien. This work was supported by Universität Wien.
article_number: e70357
article_processing_charge: Yes
article_type: original
author:
- first_name: Anna
  full_name: Vignolle, Anna
  last_name: Vignolle
- first_name: Martin
  full_name: Zehl, Martin
  id: 8e016d5b-5d77-11f0-86d2-96cdb3922a55
  last_name: Zehl
  orcid: 0000-0001-9685-0373
- first_name: Jaime Felipe Guerrero
  full_name: Garzón, Jaime Felipe Guerrero
  last_name: Garzón
- first_name: Olha
  full_name: Schneider, Olha
  last_name: Schneider
- first_name: Johannes
  full_name: Gafriller, Johannes
  last_name: Gafriller
- first_name: Ulrike
  full_name: Grienke, Ulrike
  last_name: Grienke
- first_name: Rasmus H.
  full_name: Kirkegaard, Rasmus H.
  last_name: Kirkegaard
- first_name: Sergey B.
  full_name: Zotchev, Sergey B.
  last_name: Zotchev
citation:
  ama: Vignolle A, Zehl M, Garzón JFG, et al. Identification and characterisation
    of the gene cluster governing biosynthesis of the anti-mycobacterial antibiotic
    acidomycin. <i>Microbial Biotechnology</i>. 2026;19(4). doi:<a href="https://doi.org/10.1111/1751-7915.70357">10.1111/1751-7915.70357</a>
  apa: Vignolle, A., Zehl, M., Garzón, J. F. G., Schneider, O., Gafriller, J., Grienke,
    U., … Zotchev, S. B. (2026). Identification and characterisation of the gene cluster
    governing biosynthesis of the anti-mycobacterial antibiotic acidomycin. <i>Microbial
    Biotechnology</i>. Wiley. <a href="https://doi.org/10.1111/1751-7915.70357">https://doi.org/10.1111/1751-7915.70357</a>
  chicago: Vignolle, Anna, Martin Zehl, Jaime Felipe Guerrero Garzón, Olha Schneider,
    Johannes Gafriller, Ulrike Grienke, Rasmus H. Kirkegaard, and Sergey B. Zotchev.
    “Identification and Characterisation of the Gene Cluster Governing Biosynthesis
    of the Anti-Mycobacterial Antibiotic Acidomycin.” <i>Microbial Biotechnology</i>.
    Wiley, 2026. <a href="https://doi.org/10.1111/1751-7915.70357">https://doi.org/10.1111/1751-7915.70357</a>.
  ieee: A. Vignolle <i>et al.</i>, “Identification and characterisation of the gene
    cluster governing biosynthesis of the anti-mycobacterial antibiotic acidomycin,”
    <i>Microbial Biotechnology</i>, vol. 19, no. 4. Wiley, 2026.
  ista: Vignolle A, Zehl M, Garzón JFG, Schneider O, Gafriller J, Grienke U, Kirkegaard
    RH, Zotchev SB. 2026. Identification and characterisation of the gene cluster
    governing biosynthesis of the anti-mycobacterial antibiotic acidomycin. Microbial
    Biotechnology. 19(4), e70357.
  mla: Vignolle, Anna, et al. “Identification and Characterisation of the Gene Cluster
    Governing Biosynthesis of the Anti-Mycobacterial Antibiotic Acidomycin.” <i>Microbial
    Biotechnology</i>, vol. 19, no. 4, e70357, Wiley, 2026, doi:<a href="https://doi.org/10.1111/1751-7915.70357">10.1111/1751-7915.70357</a>.
  short: A. Vignolle, M. Zehl, J.F.G. Garzón, O. Schneider, J. Gafriller, U. Grienke,
    R.H. Kirkegaard, S.B. Zotchev, Microbial Biotechnology 19 (2026).
date_created: 2026-05-03T22:01:37Z
date_published: 2026-04-01T00:00:00Z
date_updated: 2026-05-07T08:22:41Z
day: '01'
ddc:
- '570'
department:
- _id: MassSpec
doi: 10.1111/1751-7915.70357
external_id:
  pmid:
  - '42036976'
file:
- access_level: open_access
  checksum: 8c8aa660cef5394167e06f187adbabf0
  content_type: application/pdf
  creator: dernst
  date_created: 2026-05-07T08:21:06Z
  date_updated: 2026-05-07T08:21:06Z
  file_id: '21835'
  file_name: 2026_MicrobialBiotechnology_Vignolle.pdf
  file_size: 575492
  relation: main_file
  success: 1
file_date_updated: 2026-05-07T08:21:06Z
has_accepted_license: '1'
intvolume: '        19'
issue: '4'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
pmid: 1
publication: Microbial Biotechnology
publication_identifier:
  eissn:
  - 1751-7915
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Identification and characterisation of the gene cluster governing biosynthesis
  of the anti-mycobacterial antibiotic acidomycin
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 19
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '21780'
abstract:
- lang: eng
  text: It is predicted that half or more of all cataclysmic variables (CVs) should
    have evolved past the period minimum and now exist as so-called period bouncers
    where a white dwarf should be accreting from a Roche lobe filling substellar companion.
    However, this prediction stands in stark contrast to observations, where only
    a few per cent of CVs are found in this evolutionary phase. A potential solution
    to this discrepancy is that a magnetic field emerges from within the white dwarf
    after the system has reached the period minimum. The transfer of angular momentum
    from the spin of the white dwarf into the orbit then pushes the two stars apart,
    detaching them for potentially billions of years. Here we present the discovery
    of ZTF J021804.16+071152.93, a detached 0.69 +- 0.01 M⁠, 19 MG magnetic white
    dwarf plus 37 +- 5MJup brown dwarf binary with an orbital period of 1.7 h. The
    kinematics of the system indicate that it is a high probability member of the
    Galactic thick disc. However, this strongly disagrees with the much younger age
    of the system obtained from the white dwarf parameters, implying that the system
    may have been accreting in the past. This system is therefore consistent with
    having detached as a result of the emergence of the magnetic field of the white
    dwarf when the system was still mass transferring, and may represent the ultimate
    fate for many (perhaps even most) CVs.
acknowledgement: "The results presented in this paper are based on observations collected
  at the European Southern Observatory under programme IDs 113.D-0277 and 114.D-0066
  and on observations made with the Gran Telescopio Canarias (programme ID GTC119-23B),
  installed in the Spanish Observatorio del Roque de los Muchachos of the Instituto
  de Astrofísica de Canarias, on the island of La Palma.\r\n\r\nSGP acknowledges support
  by the Science and Technology Facilities Council (grant ST/B001174/1). ARM acknowledges
  support from MINECO under the PID2023-148661NB-I00 grant and by the AGAUR/Generalitat
  de Catalunya grant SGR-386/2021. RMO was funded by INTA through grant PRE-OBSERVATORIO
  and acknowledges support from project PID2023-146210NB-I00 funded by MICIU/AEI/10.13039/501100011033
  and by ERDF/EU. MZ acknowledges support from FONDECYT (grants 1250525 and 1221059).
  VSD and HiPERCAM were funded by the Science and Technology Facilities Council (grant
  ST/Z000033/1). MRS thanks for support from FONDECYT (grant No. 1221059). This project
  received funding from the European Research Council under the European Union’s Horizon
  2020 research and innovation programme (Grant agreement numbers 101002408-MOS100PC)."
article_number: stag521
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: S. G.
  full_name: Parsons, S. G.
  last_name: Parsons
- first_name: A. J.
  full_name: Brown, A. J.
  last_name: Brown
- first_name: S. L.
  full_name: Casewell, S. L.
  last_name: Casewell
- first_name: S. P.
  full_name: Littlefair, S. P.
  last_name: Littlefair
- first_name: Joannes C
  full_name: van Roestel, Joannes C
  id: 4d122fc8-6083-11f0-87a5-97d68b860333
  last_name: van Roestel
- first_name: A.
  full_name: Rebassa-Mansergas, A.
  last_name: Rebassa-Mansergas
- first_name: R.
  full_name: Murillo-Ojeda, R.
  last_name: Murillo-Ojeda
- first_name: M.
  full_name: Zorotovic, M.
  last_name: Zorotovic
- first_name: M. R.
  full_name: Schreiber, M. R.
  last_name: Schreiber
- first_name: S.
  full_name: Bagnulo, S.
  last_name: Bagnulo
- first_name: M. A.
  full_name: Stroet, M. A.
  last_name: Stroet
- first_name: N.
  full_name: Castro Segura, N.
  last_name: Castro Segura
- first_name: V. S.
  full_name: Dhillon, V. S.
  last_name: Dhillon
- first_name: M. J.
  full_name: Dyer, M. J.
  last_name: Dyer
- first_name: J. A.
  full_name: Garbutt, J. A.
  last_name: Garbutt
- first_name: M. J.
  full_name: Green, M. J.
  last_name: Green
- first_name: D.
  full_name: Jarvis, D.
  last_name: Jarvis
- first_name: M. R.
  full_name: Kennedy, M. R.
  last_name: Kennedy
- first_name: P.
  full_name: Kerry, P.
  last_name: Kerry
- first_name: J.
  full_name: Mccormac, J.
  last_name: Mccormac
- first_name: J.
  full_name: Munday, J.
  last_name: Munday
- first_name: I.
  full_name: Pelisoli, I.
  last_name: Pelisoli
- first_name: E.
  full_name: Pike, E.
  last_name: Pike
- first_name: D. I.
  full_name: Sahman, D. I.
  last_name: Sahman
- first_name: A.
  full_name: Yates, A.
  last_name: Yates
citation:
  ama: 'Parsons SG, Brown AJ, Casewell SL, et al. ZTF J021804.16+071152.93: A dead
    cataclysmic variable and potential solution to the missing period bouncer cataclysmic
    variables. <i>Monthly Notices of the Royal Astronomical Society</i>. 2026;547(4).
    doi:<a href="https://doi.org/10.1093/mnras/stag521">10.1093/mnras/stag521</a>'
  apa: 'Parsons, S. G., Brown, A. J., Casewell, S. L., Littlefair, S. P., van Roestel,
    J. C., Rebassa-Mansergas, A., … Yates, A. (2026). ZTF J021804.16+071152.93: A
    dead cataclysmic variable and potential solution to the missing period bouncer
    cataclysmic variables. <i>Monthly Notices of the Royal Astronomical Society</i>.
    Oxford University Press. <a href="https://doi.org/10.1093/mnras/stag521">https://doi.org/10.1093/mnras/stag521</a>'
  chicago: 'Parsons, S. G., A. J. Brown, S. L. Casewell, S. P. Littlefair, Joannes
    C van Roestel, A. Rebassa-Mansergas, R. Murillo-Ojeda, et al. “ZTF J021804.16+071152.93:
    A Dead Cataclysmic Variable and Potential Solution to the Missing Period Bouncer
    Cataclysmic Variables.” <i>Monthly Notices of the Royal Astronomical Society</i>.
    Oxford University Press, 2026. <a href="https://doi.org/10.1093/mnras/stag521">https://doi.org/10.1093/mnras/stag521</a>.'
  ieee: 'S. G. Parsons <i>et al.</i>, “ZTF J021804.16+071152.93: A dead cataclysmic
    variable and potential solution to the missing period bouncer cataclysmic variables,”
    <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 547, no. 4. Oxford
    University Press, 2026.'
  ista: 'Parsons SG, Brown AJ, Casewell SL, Littlefair SP, van Roestel JC, Rebassa-Mansergas
    A, Murillo-Ojeda R, Zorotovic M, Schreiber MR, Bagnulo S, Stroet MA, Castro Segura
    N, Dhillon VS, Dyer MJ, Garbutt JA, Green MJ, Jarvis D, Kennedy MR, Kerry P, Mccormac
    J, Munday J, Pelisoli I, Pike E, Sahman DI, Yates A. 2026. ZTF J021804.16+071152.93:
    A dead cataclysmic variable and potential solution to the missing period bouncer
    cataclysmic variables. Monthly Notices of the Royal Astronomical Society. 547(4),
    stag521.'
  mla: 'Parsons, S. G., et al. “ZTF J021804.16+071152.93: A Dead Cataclysmic Variable
    and Potential Solution to the Missing Period Bouncer Cataclysmic Variables.” <i>Monthly
    Notices of the Royal Astronomical Society</i>, vol. 547, no. 4, stag521, Oxford
    University Press, 2026, doi:<a href="https://doi.org/10.1093/mnras/stag521">10.1093/mnras/stag521</a>.'
  short: S.G. Parsons, A.J. Brown, S.L. Casewell, S.P. Littlefair, J.C. van Roestel,
    A. Rebassa-Mansergas, R. Murillo-Ojeda, M. Zorotovic, M.R. Schreiber, S. Bagnulo,
    M.A. Stroet, N. Castro Segura, V.S. Dhillon, M.J. Dyer, J.A. Garbutt, M.J. Green,
    D. Jarvis, M.R. Kennedy, P. Kerry, J. Mccormac, J. Munday, I. Pelisoli, E. Pike,
    D.I. Sahman, A. Yates, Monthly Notices of the Royal Astronomical Society 547 (2026).
date_created: 2026-05-03T22:01:37Z
date_published: 2026-04-01T00:00:00Z
date_updated: 2026-05-07T07:51:58Z
day: '01'
ddc:
- '520'
department:
- _id: IlCa
doi: 10.1093/mnras/stag521
external_id:
  arxiv:
  - '2603.12888'
file:
- access_level: open_access
  checksum: a64094199db4dedb12fc121b7c65fe97
  content_type: application/pdf
  creator: dernst
  date_created: 2026-05-07T07:51:06Z
  date_updated: 2026-05-07T07:51:06Z
  file_id: '21834'
  file_name: 2026_MNRAS_Parsons.pdf
  file_size: 5955512
  relation: main_file
  success: 1
file_date_updated: 2026-05-07T07:51:06Z
has_accepted_license: '1'
intvolume: '       547'
issue: '4'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
publication: Monthly Notices of the Royal Astronomical Society
publication_identifier:
  eissn:
  - 1365-2966
  issn:
  - 0035-8711
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'ZTF J021804.16+071152.93: A dead cataclysmic variable and potential solution
  to the missing period bouncer cataclysmic variables'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 547
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '21781'
abstract:
- lang: eng
  text: "Given a set A of n points (vertices) in general position in the plane, the
    complete geometric graph \r\nKn[A] consists of all (n2) segments (edges) between
    the elements of A. It is known that the edge set of every complete geometric graph
    on n vertices can be partitioned into O(n3∕2) crossing-free paths (or matchings).
    We strengthen this result under various additional assumptions on the point set.
    In particular, we prove that for a set A of n randomly selected points, uniformly
    distributed in [0,1]2, with probability tending to 1 as n→∞, the edge set of Kn[A]
    can be covered by O(nlogn) crossing-free paths and by O(n√logn) crossing-free
    matchings. On the other hand, we construct n-element point sets such that covering
    the edge set of Kn[A] requires a quadratic number of monotone paths."
acknowledgement: "Research partially supported by ERC Advanced Grant \"GeoScape\",
  no. 882971 and\r\nHungarian NKFIH grant no. K-131529. Work by the third author is
  supported by EPSRC grant\r\nEP/X013642/1. Work by the third author is partially
  supported by the European Research Council (ERC), grant no. 788183, and by the Wittgenstein
  Prize, Austrian Science Fund (FWF), grant no. Z 342-N31."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Adrian
  full_name: Dumitrescu, Adrian
  last_name: Dumitrescu
- first_name: János
  full_name: Pach, János
  last_name: Pach
- first_name: Morteza
  full_name: Saghafian, Morteza
  id: f86f7148-b140-11ec-9577-95435b8df824
  last_name: Saghafian
- first_name: Alex
  full_name: Scott, Alex
  last_name: Scott
citation:
  ama: Dumitrescu A, Pach J, Saghafian M, Scott A. Covering complete geometric graphs
    by monotone paths. <i>Combinatorics and Number Theory</i>. 2026;15(1):73-82. doi:<a
    href="https://doi.org/10.2140/cnt.2026.15.73">10.2140/cnt.2026.15.73</a>
  apa: Dumitrescu, A., Pach, J., Saghafian, M., &#38; Scott, A. (2026). Covering complete
    geometric graphs by monotone paths. <i>Combinatorics and Number Theory</i>. Mathematical
    Sciences Publishers. <a href="https://doi.org/10.2140/cnt.2026.15.73">https://doi.org/10.2140/cnt.2026.15.73</a>
  chicago: Dumitrescu, Adrian, János Pach, Morteza Saghafian, and Alex Scott. “Covering
    Complete Geometric Graphs by Monotone Paths.” <i>Combinatorics and Number Theory</i>.
    Mathematical Sciences Publishers, 2026. <a href="https://doi.org/10.2140/cnt.2026.15.73">https://doi.org/10.2140/cnt.2026.15.73</a>.
  ieee: A. Dumitrescu, J. Pach, M. Saghafian, and A. Scott, “Covering complete geometric
    graphs by monotone paths,” <i>Combinatorics and Number Theory</i>, vol. 15, no.
    1. Mathematical Sciences Publishers, pp. 73–82, 2026.
  ista: Dumitrescu A, Pach J, Saghafian M, Scott A. 2026. Covering complete geometric
    graphs by monotone paths. Combinatorics and Number Theory. 15(1), 73–82.
  mla: Dumitrescu, Adrian, et al. “Covering Complete Geometric Graphs by Monotone
    Paths.” <i>Combinatorics and Number Theory</i>, vol. 15, no. 1, Mathematical Sciences
    Publishers, 2026, pp. 73–82, doi:<a href="https://doi.org/10.2140/cnt.2026.15.73">10.2140/cnt.2026.15.73</a>.
  short: A. Dumitrescu, J. Pach, M. Saghafian, A. Scott, Combinatorics and Number
    Theory 15 (2026) 73–82.
date_created: 2026-05-03T22:01:37Z
date_published: 2026-04-17T00:00:00Z
date_updated: 2026-05-07T07:45:24Z
day: '17'
department:
- _id: HeEd
doi: 10.2140/cnt.2026.15.73
ec_funded: 1
external_id:
  arxiv:
  - '2507.10840'
intvolume: '        15'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2507.10840
month: '04'
oa: 1
oa_version: Preprint
page: 73-82
project:
- _id: 266A2E9E-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '788183'
  name: Alpha Shape Theory Extended
- _id: 268116B8-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Z00342
  name: Mathematics, Computer Science
publication: Combinatorics and Number Theory
publication_identifier:
  eissn:
  - 2996-220X
  issn:
  - 2996-2196
publication_status: published
publisher: Mathematical Sciences Publishers
quality_controlled: '1'
scopus_import: '1'
status: public
title: Covering complete geometric graphs by monotone paths
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 15
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '21800'
abstract:
- lang: eng
  text: 'LAMMPS input scripts to simulate toroidal vesicles composed of pure bolalipid
    membranes and archaeal mixture membranes for the following publication: "Cracking
    donuts and sorting lipids: geometry controls archaeal membrane stability and lipid
    organization" by Felix Frey, Miguel Amaral, and Andela Saric.'
article_processing_charge: No
author:
- first_name: Felix F
  full_name: Frey, Felix F
  id: a0270b37-8f1a-11ec-95c7-8e710c59a4f3
  last_name: Frey
  orcid: 0000-0001-8501-6017
- first_name: Miguel
  full_name: Santana de Freitas Amaral, Miguel
  id: 4f2d02dd-47a9-11ec-ad10-82820ed3f501
  last_name: Santana de Freitas Amaral
- first_name: Anđela
  full_name: Šarić, Anđela
  id: bf63d406-f056-11eb-b41d-f263a6566d8b
  last_name: Šarić
  orcid: 0000-0002-7854-2139
citation:
  ama: 'Frey FF, Santana de Freitas Amaral M, Šarić A. Cracking donuts and sorting
    lipids: Geometry controls archaeal membrane stability and lipid organization.
    2026. doi:<a href="https://doi.org/10.5281/ZENODO.18772086">10.5281/ZENODO.18772086</a>'
  apa: 'Frey, F. F., Santana de Freitas Amaral, M., &#38; Šarić, A. (2026). Cracking
    donuts and sorting lipids: Geometry controls archaeal membrane stability and lipid
    organization. Zenodo. <a href="https://doi.org/10.5281/ZENODO.18772086">https://doi.org/10.5281/ZENODO.18772086</a>'
  chicago: 'Frey, Felix F, Miguel Santana de Freitas Amaral, and Anđela Šarić. “Cracking
    Donuts and Sorting Lipids: Geometry Controls Archaeal Membrane Stability and Lipid
    Organization.” Zenodo, 2026. <a href="https://doi.org/10.5281/ZENODO.18772086">https://doi.org/10.5281/ZENODO.18772086</a>.'
  ieee: 'F. F. Frey, M. Santana de Freitas Amaral, and A. Šarić, “Cracking donuts
    and sorting lipids: Geometry controls archaeal membrane stability and lipid organization.”
    Zenodo, 2026.'
  ista: 'Frey FF, Santana de Freitas Amaral M, Šarić A. 2026. Cracking donuts and
    sorting lipids: Geometry controls archaeal membrane stability and lipid organization,
    Zenodo, <a href="https://doi.org/10.5281/ZENODO.18772086">10.5281/ZENODO.18772086</a>.'
  mla: 'Frey, Felix F., et al. <i>Cracking Donuts and Sorting Lipids: Geometry Controls
    Archaeal Membrane Stability and Lipid Organization</i>. Zenodo, 2026, doi:<a href="https://doi.org/10.5281/ZENODO.18772086">10.5281/ZENODO.18772086</a>.'
  short: F.F. Frey, M. Santana de Freitas Amaral, A. Šarić, (2026).
corr_author: '1'
date_created: 2026-05-05T12:11:52Z
date_published: 2026-02-25T00:00:00Z
date_updated: 2026-05-05T12:40:41Z
day: '25'
ddc:
- '540'
department:
- _id: AnSa
doi: 10.5281/ZENODO.18772086
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5281/ZENODO.18772086
month: '02'
oa: 1
oa_version: Published Version
publisher: Zenodo
related_material:
  record:
  - id: '21748'
    relation: used_in_publication
    status: public
status: public
title: 'Cracking donuts and sorting lipids: Geometry controls archaeal membrane stability
  and lipid organization'
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21837'
abstract:
- lang: eng
  text: 'In a warming world of glacier changes, the scientific community has dedicated
    increasing attention to debris-covered glaciers and their response to climate.
    A variety of models with distinct complexity and data requirements have been developed
    and widely used to simulate melt under debris at different sites and scales, but
    their skills have never been compared. As part of the activities of the International
    Association of Cryospheric Sciences (IACS) Debris Covered Glacier Working Group,
    we present an intercomparison exercise aimed at advancing our understanding of
    model skills in simulating ice melt under a debris layer. We compare 15 models
    with different complexity at nine sites in the European Alps, Caucasus, Chilean
    Andes, Nepalese Himalaya and the Southern Alps of New Zealand, over one melt season.
    We run the models with measured meteorological data from automatic weather stations
    and estimated or measured debris properties. We consider four main model categories:
    (i) energy balance models that calculate melt by solving the physics of heat transfer
    to the debris layer, but require a high amount of input data; (ii) a simplified
    energy balance model; (iii) enhanced temperature-index models; and (iv) simple
    empirical temperature-index models that have been extensively used given their
    low data requirement but require calibration of their empirical parameters. Model
    performance is evaluated using on-site measurements of sub-debris melt (for all
    models) and surface temperature (for models based on the surface energy balance).
    Our results show that physically-based energy balance models and empirical temperature-index
    models perform in a distinct manner. At one end of the spectrum, simple temperature-index
    models are accurate when recalibrated or when using site-specific literature parameters,
    and show poor results when parameters are uncalibrated. At the other end, energy
    balance models show a range of performance: the most accurate energy balance models
    are those with the highest degree of complexity at the atmosphere-debris interface.
    An important data gap emerged from our experiment: the poor performance of all
    models at three sites was related to the poor knowledge of debris properties,
    and specifically of thermal conductivity. Future work should focus on both: (i) consistent
    data acquisition to evaluate existing models and support new model developments;
    (ii) advancing models by accounting for processes such as debris-snow interactions,
    moisture in the debris and refreezing. We suggest that a systematic effort of
    model development using a common model framework could be carried out in phase
    II of the Working Group.'
acknowledgement: "This project has received funding from the European Research Council
  (ERC) under the European Union’s Horizon 2020 research and innovation programme
  grant agreement No\r\n772751, RAVEN, “Rapid mass losses of debris covered glaciers
  in\r\nHigh Mountain Asia”. It was also supported by the SNSF RENOIR\r\nproject “Resolving
  the thickness of debris on Earth’s glaciers and\r\nits rate of change (RENOIR)”,
  project number 204322.\r\nDavid Rounce received support from NASA-ROSES program\r\ngrants
  NNX17AB27G and 80NSSC17K0566. Walter Immerzeel\r\nand Jakob Steiner acknowledge
  support from the European Research Council (ERC) under the European Union’s Horizon
  2020\r\nresearch and innovation program (grant agreement no. 676819).\r\nBen Brock
  acknowledges support from the EU/FP7 ACQWA\r\n(Assessing Climate impacts on the
  Quantity and quality of WAter) project, NERC grant NE/C514282/1, the British Council-Italian\r\nMinistry
  of University and Research Partnership programme and\r\nthe Carnegie Trust for the
  Universities of Scotland.\r\nThe authors acknowledge the International Association
  of\r\nCryospheric Sciences (IACS) for supporting the creation of the\r\nDebris-Covered
  Glaciers Working Group (DCG-WG) which enabled this model intercomparison experiment.\r\nThe
  authors thank Martin Heynen for producing Figs. 3 and 4.\r\nThe authors thank Duncan
  Quincey and Richard Essery for their\r\nconstructive feedback and comments.\r\n"
article_processing_charge: Yes
article_type: original
author:
- first_name: Francesca
  full_name: Pellicciotti, Francesca
  id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
  last_name: Pellicciotti
  orcid: 0000-0002-5554-8087
- first_name: Adrià
  full_name: Fontrodona-Bach, Adrià
  id: f06891fd-9f42-11ee-8632-a20971c43046
  last_name: Fontrodona-Bach
- first_name: David R.
  full_name: Rounce, David R.
  last_name: Rounce
- first_name: Catriona Louise
  full_name: Fyffe, Catriona Louise
  id: 001b0422-8d15-11ed-bc51-cab6c037a228
  last_name: Fyffe
- first_name: Leif S.
  full_name: Anderson, Leif S.
  last_name: Anderson
- first_name: Álvaro
  full_name: Ayala, Álvaro
  last_name: Ayala
- first_name: Ben W.
  full_name: Brock, Ben W.
  last_name: Brock
- first_name: Pascal
  full_name: Buri, Pascal
  last_name: Buri
- first_name: Stefan
  full_name: Fugger, Stefan
  last_name: Fugger
- first_name: Koji
  full_name: Fujita, Koji
  last_name: Fujita
- first_name: PRATEEK
  full_name: GANTAYAT, PRATEEK
  id: 02734268-3e8d-11ef-80a1-cec4a088d004
  last_name: GANTAYAT
- first_name: Alexander R.
  full_name: Groos, Alexander R.
  last_name: Groos
- first_name: Walter
  full_name: Immerzeel, Walter
  last_name: Immerzeel
- first_name: Marin
  full_name: Kneib, Marin
  last_name: Kneib
- first_name: Christoph
  full_name: Mayer, Christoph
  last_name: Mayer
- first_name: Shelley
  full_name: MacDonell, Shelley
  last_name: MacDonell
- first_name: Michael
  full_name: McCarthy, Michael
  id: 22a2674a-61ce-11ee-94b5-d18813baf16f
  last_name: McCarthy
- first_name: James
  full_name: McPhee, James
  last_name: McPhee
- first_name: Evan
  full_name: Miles, Evan
  last_name: Miles
- first_name: Heather
  full_name: Purdie, Heather
  last_name: Purdie
- first_name: Ekaterina
  full_name: Rets, Ekaterina
  last_name: Rets
- first_name: Akiko
  full_name: Sakai, Akiko
  last_name: Sakai
- first_name: Thomas
  full_name: Shaw, Thomas
  id: 3caa3f91-1f03-11ee-96ce-e0e553054d6e
  last_name: Shaw
  orcid: 0000-0001-7640-6152
- first_name: Jakob
  full_name: Steiner, Jakob
  last_name: Steiner
- first_name: Patrick
  full_name: Wagnon, Patrick
  last_name: Wagnon
- first_name: Alex
  full_name: Winter-Billington, Alex
  last_name: Winter-Billington
citation:
  ama: 'Pellicciotti F, Fontrodona-Bach A, Rounce DR, et al. DCG-MIP: The debris-covered
    glacier melt model intercomparison experiment. <i>The Cryosphere</i>. 2026;20(3):1895-1928.
    doi:<a href="https://doi.org/10.5194/tc-20-1895-2026">10.5194/tc-20-1895-2026</a>'
  apa: 'Pellicciotti, F., Fontrodona-Bach, A., Rounce, D. R., Fyffe, C. L., Anderson,
    L. S., Ayala, Á., … Winter-Billington, A. (2026). DCG-MIP: The debris-covered
    glacier melt model intercomparison experiment. <i>The Cryosphere</i>. Copernicus
    Publications. <a href="https://doi.org/10.5194/tc-20-1895-2026">https://doi.org/10.5194/tc-20-1895-2026</a>'
  chicago: 'Pellicciotti, Francesca, Adrià Fontrodona-Bach, David R. Rounce, Catriona
    Louise Fyffe, Leif S. Anderson, Álvaro Ayala, Ben W. Brock, et al. “DCG-MIP: The
    Debris-Covered Glacier Melt Model Intercomparison Experiment.” <i>The Cryosphere</i>.
    Copernicus Publications, 2026. <a href="https://doi.org/10.5194/tc-20-1895-2026">https://doi.org/10.5194/tc-20-1895-2026</a>.'
  ieee: 'F. Pellicciotti <i>et al.</i>, “DCG-MIP: The debris-covered glacier melt
    model intercomparison experiment,” <i>The Cryosphere</i>, vol. 20, no. 3. Copernicus
    Publications, pp. 1895–1928, 2026.'
  ista: 'Pellicciotti F, Fontrodona-Bach A, Rounce DR, Fyffe CL, Anderson LS, Ayala
    Á, Brock BW, Buri P, Fugger S, Fujita K, GANTAYAT P, Groos AR, Immerzeel W, Kneib
    M, Mayer C, MacDonell S, McCarthy M, McPhee J, Miles E, Purdie H, Rets E, Sakai
    A, Shaw T, Steiner J, Wagnon P, Winter-Billington A. 2026. DCG-MIP: The debris-covered
    glacier melt model intercomparison experiment. The Cryosphere. 20(3), 1895–1928.'
  mla: 'Pellicciotti, Francesca, et al. “DCG-MIP: The Debris-Covered Glacier Melt
    Model Intercomparison Experiment.” <i>The Cryosphere</i>, vol. 20, no. 3, Copernicus
    Publications, 2026, pp. 1895–928, doi:<a href="https://doi.org/10.5194/tc-20-1895-2026">10.5194/tc-20-1895-2026</a>.'
  short: F. Pellicciotti, A. Fontrodona-Bach, D.R. Rounce, C.L. Fyffe, L.S. Anderson,
    Á. Ayala, B.W. Brock, P. Buri, S. Fugger, K. Fujita, P. GANTAYAT, A.R. Groos,
    W. Immerzeel, M. Kneib, C. Mayer, S. MacDonell, M. McCarthy, J. McPhee, E. Miles,
    H. Purdie, E. Rets, A. Sakai, T. Shaw, J. Steiner, P. Wagnon, A. Winter-Billington,
    The Cryosphere 20 (2026) 1895–1928.
corr_author: '1'
date_created: 2026-05-07T08:48:38Z
date_published: 2026-04-02T00:00:00Z
date_updated: 2026-05-18T06:12:56Z
day: '02'
ddc:
- '550'
department:
- _id: FrPe
doi: 10.5194/tc-20-1895-2026
file:
- access_level: open_access
  checksum: f15abad4ee360d41a3e8794f068711fc
  content_type: application/pdf
  creator: dernst
  date_created: 2026-05-18T06:07:53Z
  date_updated: 2026-05-18T06:07:53Z
  file_id: '21886'
  file_name: 2026_Cryosphere_Pellicciotti.pdf
  file_size: 3168394
  relation: main_file
  success: 1
file_date_updated: 2026-05-18T06:07:53Z
has_accepted_license: '1'
intvolume: '        20'
issue: '3'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 1895-1928
publication: The Cryosphere
publication_identifier:
  eissn:
  - 1994-0424
publication_status: published
publisher: Copernicus Publications
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'DCG-MIP: The debris-covered glacier melt model intercomparison experiment'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 20
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21838'
abstract:
- lang: eng
  text: We explore the use of a photoacid in a chemical reaction cycle, which allows
    for the controlled sol‐to‐gel transition of a saccharide aldehyde‐based self‐assembling
    system. The modulation of the pH with light enables to generate chemical fuels
    in situ, thus triggering monomer activation and gelation. Our efforts represent
    a promising step toward dissipative self‐assembled systems with a higher degree
    of spatiotemporal control.
acknowledgement: J.S.V. and T.M.H. acknowledge funding from ERC-2017-STG “Life-Cycle”
  (757910) and ERC-2022-CoG “Suprabot” (101087514). A.L-A. acknowledges the European
  Union's Horizon 2020 Research and Innovation Program under the Marie Skłodowska-Curie
  grant agreement no. 812868 for Ph.D. funding. R.K. acknowledges support through
  the Award for Research Cooperation and High Excellence in Science (ARCHES) from
  the Federal German Ministry and Research.
article_number: e70037
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Alvaro
  full_name: Lopez‐Acosta, Alvaro
  last_name: Lopez‐Acosta
- first_name: Jorge S.
  full_name: Valera, Jorge S.
  last_name: Valera
- first_name: Rafal
  full_name: Klajn, Rafal
  id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
  last_name: Klajn
- first_name: Thomas M.
  full_name: Hermans, Thomas M.
  last_name: Hermans
citation:
  ama: Lopez‐Acosta A, Valera JS, Klajn R, Hermans TM. Photoacid‐mediated controllable
    gelation in a chemical reaction cycle. <i>ChemSystemsChem</i>. 2026;8(3). doi:<a
    href="https://doi.org/10.1002/syst.70037">10.1002/syst.70037</a>
  apa: Lopez‐Acosta, A., Valera, J. S., Klajn, R., &#38; Hermans, T. M. (2026). Photoacid‐mediated
    controllable gelation in a chemical reaction cycle. <i>ChemSystemsChem</i>. Wiley.
    <a href="https://doi.org/10.1002/syst.70037">https://doi.org/10.1002/syst.70037</a>
  chicago: Lopez‐Acosta, Alvaro, Jorge S. Valera, Rafal Klajn, and Thomas M. Hermans.
    “Photoacid‐mediated Controllable Gelation in a Chemical Reaction Cycle.” <i>ChemSystemsChem</i>.
    Wiley, 2026. <a href="https://doi.org/10.1002/syst.70037">https://doi.org/10.1002/syst.70037</a>.
  ieee: A. Lopez‐Acosta, J. S. Valera, R. Klajn, and T. M. Hermans, “Photoacid‐mediated
    controllable gelation in a chemical reaction cycle,” <i>ChemSystemsChem</i>, vol.
    8, no. 3. Wiley, 2026.
  ista: Lopez‐Acosta A, Valera JS, Klajn R, Hermans TM. 2026. Photoacid‐mediated controllable
    gelation in a chemical reaction cycle. ChemSystemsChem. 8(3), e70037.
  mla: Lopez‐Acosta, Alvaro, et al. “Photoacid‐mediated Controllable Gelation in a
    Chemical Reaction Cycle.” <i>ChemSystemsChem</i>, vol. 8, no. 3, e70037, Wiley,
    2026, doi:<a href="https://doi.org/10.1002/syst.70037">10.1002/syst.70037</a>.
  short: A. Lopez‐Acosta, J.S. Valera, R. Klajn, T.M. Hermans, ChemSystemsChem 8 (2026).
date_created: 2026-05-07T08:51:01Z
date_published: 2026-04-06T00:00:00Z
date_updated: 2026-05-18T06:59:10Z
day: '06'
ddc:
- '540'
department:
- _id: RaKl
doi: 10.1002/syst.70037
file:
- access_level: open_access
  checksum: c51e985ac2f2cefb273fdf2cc6ab87e4
  content_type: application/pdf
  creator: dernst
  date_created: 2026-05-18T06:29:57Z
  date_updated: 2026-05-18T06:29:57Z
  file_id: '21887'
  file_name: 2026_ChemSystemsChem_LopezAcosta.pdf
  file_size: 1118636
  relation: main_file
  success: 1
file_date_updated: 2026-05-18T06:29:57Z
has_accepted_license: '1'
intvolume: '         8'
issue: '3'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
publication: ChemSystemsChem
publication_identifier:
  eissn:
  - 2570-4206
publication_status: published
publisher: Wiley
quality_controlled: '1'
status: public
title: Photoacid‐mediated controllable gelation in a chemical reaction cycle
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21840'
abstract:
- lang: eng
  text: The transport properties of nanofluidic channels are usually studied under
    constant (DC) voltage or pressure driving. However, the frequency response under
    sinusoidal (AC) drivings offers rich insights into the time-dependent transport
    mechanisms. Inspired by recent electrochemical approaches, we investigate the
    couplings between ionic and electronic transport under AC driving. We show that
    conduction electrons of the channel walls participate in ionic current via capacitive
    electrochemical coupling, defining a critical frequency and length scale where
    electron-dominated conductivity emerges. We further analyze how electron–ion coupling
    modifies electro-osmotic flows and demonstrate that fluctuation-induced momentum
    transfer between the electrolyte and wall electrons produces distinct AC transport
    signatures, depending on the charge carrier polarity. Altogether, we establish
    a frequency-dependent transport matrix that couples ionic, electronic, and hydrodynamic
    flows. These findings establish AC nanofluidic transport as a powerful probe of
    interfacial phenomena under confinement and suggest new directions for engineering
    nanofluidic functionalities through electron–electrolyte coupling.
acknowledgement: The authors thank Nicolas Chapuis for fruitful discussions. L.B.
  acknowledges support from the ERC project n-AQUA under Grant Agreement No. 101071937.
  B.C. acknowledges support from the CFM Foundation and the NOMIS Foundation. N.K.
  acknowledges support from the Swiss National Science Foundation (SNSF) under Grant
  No. CRSK-2_237930.
article_number: '134704'
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Baptiste
  full_name: Coquinot, Baptiste
  id: f8417bd4-f599-11ee-a482-b927e3ed1e8e
  last_name: Coquinot
  orcid: 0000-0001-5524-596X
- first_name: Mathieu
  full_name: Lizée, Mathieu
  last_name: Lizée
- first_name: Lydéric
  full_name: Bocquet, Lydéric
  last_name: Bocquet
- first_name: Nikita
  full_name: Kavokine, Nikita
  last_name: Kavokine
citation:
  ama: Coquinot B, Lizée M, Bocquet L, Kavokine N. Electron–electrolyte coupling in
    AC transport through nanofluidic channels. <i>The Journal of Chemical Physics</i>.
    2026;164(13). doi:<a href="https://doi.org/10.1063/5.0313352">10.1063/5.0313352</a>
  apa: Coquinot, B., Lizée, M., Bocquet, L., &#38; Kavokine, N. (2026). Electron–electrolyte
    coupling in AC transport through nanofluidic channels. <i>The Journal of Chemical
    Physics</i>. AIP Publishing. <a href="https://doi.org/10.1063/5.0313352">https://doi.org/10.1063/5.0313352</a>
  chicago: Coquinot, Baptiste, Mathieu Lizée, Lydéric Bocquet, and Nikita Kavokine.
    “Electron–Electrolyte Coupling in AC Transport through Nanofluidic Channels.”
    <i>The Journal of Chemical Physics</i>. AIP Publishing, 2026. <a href="https://doi.org/10.1063/5.0313352">https://doi.org/10.1063/5.0313352</a>.
  ieee: B. Coquinot, M. Lizée, L. Bocquet, and N. Kavokine, “Electron–electrolyte
    coupling in AC transport through nanofluidic channels,” <i>The Journal of Chemical
    Physics</i>, vol. 164, no. 13. AIP Publishing, 2026.
  ista: Coquinot B, Lizée M, Bocquet L, Kavokine N. 2026. Electron–electrolyte coupling
    in AC transport through nanofluidic channels. The Journal of Chemical Physics.
    164(13), 134704.
  mla: Coquinot, Baptiste, et al. “Electron–Electrolyte Coupling in AC Transport through
    Nanofluidic Channels.” <i>The Journal of Chemical Physics</i>, vol. 164, no. 13,
    134704, AIP Publishing, 2026, doi:<a href="https://doi.org/10.1063/5.0313352">10.1063/5.0313352</a>.
  short: B. Coquinot, M. Lizée, L. Bocquet, N. Kavokine, The Journal of Chemical Physics
    164 (2026).
date_created: 2026-05-07T08:53:03Z
date_published: 2026-04-07T00:00:00Z
date_updated: 2026-05-18T07:34:57Z
day: '07'
ddc:
- '530'
department:
- _id: MiLe
doi: 10.1063/5.0313352
external_id:
  arxiv:
  - '2505.02478'
file:
- access_level: open_access
  checksum: a896969c829be2a79859bd277f87b44c
  content_type: application/pdf
  creator: dernst
  date_created: 2026-05-18T07:31:23Z
  date_updated: 2026-05-18T07:31:23Z
  file_id: '21889'
  file_name: 2026_JourChemPhysics_Coquinot.pdf
  file_size: 5497515
  relation: main_file
  success: 1
file_date_updated: 2026-05-18T07:31:23Z
has_accepted_license: '1'
intvolume: '       164'
issue: '13'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
publication: The Journal of Chemical Physics
publication_identifier:
  eissn:
  - 1089-7690
  issn:
  - 0021-9606
publication_status: published
publisher: AIP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: Electron–electrolyte coupling in AC transport through nanofluidic channels
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 164
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21841'
abstract:
- lang: eng
  text: The long-standing notion that genotypes map to phenotypes through simple one
    gene–one trait relationships continues to shape both research in the life sciences
    and public understanding, with implications for policy and funding priorities.
    Yet this paradigm is increasingly recognized as inadequate for explaining continuous
    phenotypic variation and the complex genetic architectures of the genotype–phenotype
    map. Modern genetics emerged from the early 20th-century synthesis of Mendelian
    and biometric schools of heredity, with R.A. Fisher demonstrating early on how
    multiple discrete loci could collectively produce continuous variation. Despite
    this fundamental insight, Mendelism—with its focus on single genes and standardized
    genetic backgrounds—became the dominant framework, shaping current genetics research
    and molecular biology as well as science education. The advent of large-scale
    genomic data has revealed yet again the limitations of this reductionist approach.
    Evidence from quantitative genetics now shows that most phenotypes arise from
    complex networks of many interdependent genes and their dynamic responses to environmental
    perturbations. Here we trace the historical roots of how Mendelian classical genetics
    departed from the biometric school to create the current predominant paradigm
    in genetics, despite fundamentally unresolved issues. Moving on from this one-sided
    paradigm will require systematic development of integrative, evolutionarily grounded
    experimental approaches that better capture the multigenic and context-dependent
    nature of inheritance. Achieving such an extended perspective will require methodological
    innovation, including advances in large-scale (e.g. automated) phenotyping. Dedicated
    research programs will be necessary to advance a new era of genetic research into
    the complex mechanisms underlying phenotypic variation.
acknowledgement: We thank a variety of further colleagues for the many inspiring discussions
  on the nature of heredity, especially the workshops in Berlin. Special thanks also
  to the Stellenbosch Institute for Advanced Studies (STIAS) to provide DT the leisure
  and freedom to write up the first version of this perspective. Thanks also to three
  reviewers who have helped to improve the manuscript. Two dedicated symposia on the
  topic were funded by the Max-Planck Society.
article_number: iyag024
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Diethard
  full_name: Tautz, Diethard
  last_name: Tautz
- first_name: Luisa F
  full_name: Pallares, Luisa F
  last_name: Pallares
- first_name: Leif
  full_name: Andersson, Leif
  last_name: Andersson
- first_name: Neda
  full_name: Barghi, Neda
  last_name: Barghi
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Rachael
  full_name: Bay, Rachael
  last_name: Bay
- first_name: Yingguang Frank
  full_name: Chan, Yingguang Frank
  last_name: Chan
- first_name: Angela
  full_name: Hancock, Angela
  last_name: Hancock
- first_name: Tobias S
  full_name: Kaiser, Tobias S
  last_name: Kaiser
- first_name: Daniel
  full_name: Koenig, Daniel
  last_name: Koenig
- first_name: Zacharias
  full_name: Kontarakis, Zacharias
  last_name: Kontarakis
- first_name: Miriam
  full_name: Liedvogel, Miriam
  last_name: Liedvogel
- first_name: Juliette
  full_name: de Meaux, Juliette
  last_name: de Meaux
- first_name: Magnus
  full_name: Nordborg, Magnus
  last_name: Nordborg
- first_name: Abraham A
  full_name: Palmer, Abraham A
  last_name: Palmer
- first_name: Michael
  full_name: Purugganan, Michael
  last_name: Purugganan
- first_name: Christian
  full_name: Schlötterer, Christian
  last_name: Schlötterer
- first_name: Karl
  full_name: Schmid, Karl
  last_name: Schmid
- first_name: Didier Y R
  full_name: Stainier, Didier Y R
  last_name: Stainier
- first_name: Detlef
  full_name: Weigel, Detlef
  last_name: Weigel
- first_name: Jochen B W
  full_name: Wolf, Jochen B W
  last_name: Wolf
- first_name: Dieter
  full_name: Ebert, Dieter
  last_name: Ebert
- first_name: Greg
  full_name: Gibson, Greg
  last_name: Gibson
citation:
  ama: 'Tautz D, Pallares LF, Andersson L, et al. Beyond Mendel: A call to revisit
    the genotype–phenotype map through new experimental paradigms. <i>Genetics</i>.
    2026;232(4). doi:<a href="https://doi.org/10.1093/genetics/iyag024">10.1093/genetics/iyag024</a>'
  apa: 'Tautz, D., Pallares, L. F., Andersson, L., Barghi, N., Barton, N. H., Bay,
    R., … Gibson, G. (2026). Beyond Mendel: A call to revisit the genotype–phenotype
    map through new experimental paradigms. <i>Genetics</i>. Oxford University Press.
    <a href="https://doi.org/10.1093/genetics/iyag024">https://doi.org/10.1093/genetics/iyag024</a>'
  chicago: 'Tautz, Diethard, Luisa F Pallares, Leif Andersson, Neda Barghi, Nicholas
    H Barton, Rachael Bay, Yingguang Frank Chan, et al. “Beyond Mendel: A Call to
    Revisit the Genotype–Phenotype Map through New Experimental Paradigms.” <i>Genetics</i>.
    Oxford University Press, 2026. <a href="https://doi.org/10.1093/genetics/iyag024">https://doi.org/10.1093/genetics/iyag024</a>.'
  ieee: 'D. Tautz <i>et al.</i>, “Beyond Mendel: A call to revisit the genotype–phenotype
    map through new experimental paradigms,” <i>Genetics</i>, vol. 232, no. 4. Oxford
    University Press, 2026.'
  ista: 'Tautz D, Pallares LF, Andersson L, Barghi N, Barton NH, Bay R, Chan YF, Hancock
    A, Kaiser TS, Koenig D, Kontarakis Z, Liedvogel M, de Meaux J, Nordborg M, Palmer
    AA, Purugganan M, Schlötterer C, Schmid K, Stainier DYR, Weigel D, Wolf JBW, Ebert
    D, Gibson G. 2026. Beyond Mendel: A call to revisit the genotype–phenotype map
    through new experimental paradigms. Genetics. 232(4), iyag024.'
  mla: 'Tautz, Diethard, et al. “Beyond Mendel: A Call to Revisit the Genotype–Phenotype
    Map through New Experimental Paradigms.” <i>Genetics</i>, vol. 232, no. 4, iyag024,
    Oxford University Press, 2026, doi:<a href="https://doi.org/10.1093/genetics/iyag024">10.1093/genetics/iyag024</a>.'
  short: D. Tautz, L.F. Pallares, L. Andersson, N. Barghi, N.H. Barton, R. Bay, Y.F.
    Chan, A. Hancock, T.S. Kaiser, D. Koenig, Z. Kontarakis, M. Liedvogel, J. de Meaux,
    M. Nordborg, A.A. Palmer, M. Purugganan, C. Schlötterer, K. Schmid, D.Y.R. Stainier,
    D. Weigel, J.B.W. Wolf, D. Ebert, G. Gibson, Genetics 232 (2026).
date_created: 2026-05-07T08:53:40Z
date_published: 2026-04-01T00:00:00Z
date_updated: 2026-05-18T07:51:26Z
day: '01'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1093/genetics/iyag024
external_id:
  pmid:
  - '41701356'
file:
- access_level: open_access
  checksum: 5a862c539f9dec4511277ad8927c549c
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  creator: dernst
  date_created: 2026-05-18T07:48:45Z
  date_updated: 2026-05-18T07:48:45Z
  file_id: '21890'
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  file_size: 542844
  relation: main_file
  success: 1
file_date_updated: 2026-05-18T07:48:45Z
has_accepted_license: '1'
intvolume: '       232'
issue: '4'
keyword:
- classic genetics
- quantitative genetics
- genotype–phenotype map
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
pmid: 1
publication: Genetics
publication_identifier:
  eissn:
  - 1943-2631
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Beyond Mendel: A call to revisit the genotype–phenotype map through new experimental
  paradigms'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 232
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21842'
abstract:
- lang: eng
  text: "AM CVn stars are ultra-compact semi-detached binaries consisting of a white
    dwarf primary and a hydrogen-depleted secondary. In this\r\npaper, we present
    spectroscopic and photometric results of 15 transient sources pre-classified as
    AM CVn candidates. Our analysis confirms\r\n9 systems of the type AM CVn, 3 hydrogen-rich
    cataclysmic variables (accreting white dwarfs with near-main-sequence stars for
    donors),\r\nand 3 systems that could be evolved cataclysmic variables. Eight of
    the AM CVn stars are analysed spectroscopically for the first time,\r\nwhich increases
    the number of spectroscopically confirmed AM CVns by about 10%. TESS data revealed
    the orbital period of the AM CVn\r\nstar ASASSN-20pv to be Porb =27.282 min, which
    helps to constrain the possible values of its mass ratio. TESS also helped to
    determine\r\nthe superhump periods of one AM CVn star (ASASSN-19ct, Psh =30.94
    min) and two cataclysmic variables we classify as WZ Sge stars\r\n(Psh =90.77
    min for ZTF18aaaasnn and Psh =91.6min for ASASSN-15na).We identified very different
    abundances in the spectra of theAM\r\nCVns binaries ASASSN-15kf and ASASSN-20pv
    (both Porb ∼27.5min), suggesting different type of donors. Six of the studied
    AMCVns are\r\nX-ray sources, which helped to determine their mass accretion rates.
    Photometry shows that the duration of all the superoutbursts detected\r\nin the
    AM CVns is consistent with expectations from the disc instability model. Finally,
    we provide refined criteria for the identification of\r\nnew systems using all-sky
    surveys such as LSST."
acknowledgement: "We are grateful to the anonymous referee for providing\r\nus with
  useful comments and suggestions that improved our manuscript.\r\nJK and LRS acknowledge
  support from NASA grants NNH22ZDA001N-6152\r\nand 80NSSC24K0638. MPM is partially
  supported by the Swiss National\r\nScience Foundation IZSTZ0_216537 and by UNAM
  PAPIIT-IG101224. Based\r\non observations obtained at the international Gemini Observatory,
  a program\r\nof NSF NOIRLab, which is managed by the Association of Universities
  for\r\nResearch in Astronomy (AURA) under a cooperative agreement with the U.S.\r\nNational
  Science Foundation on behalf of the Gemini Observatory partnership:\r\nthe U.S.
  National Science Foundation (United States), National Research\r\nCouncil (Canada),
  Agencia Nacional de Investigación y Desarrollo (Chile), Ministerio de Ciencia, Tecnología
  e Innovación (Argentina), Ministério\r\nda Ciência, Tecnologia, Inovações e Comunicações
  (Brazil), and Korea\r\nAstronomy and Space Science Institute (Republic of Korea).
  The Gemini\r\ndata were obtained from programs GN-2023B-Q-310 and GS-2024A-Q-311\r\n(PI:
  Rivera Sandoval) and processed using DRAGONS (Data Reduction for\r\nAstronomy from
  Gemini Observatory North and South) The Digitized Sky\r\nSurveys were produced at
  the Space Telescope Science Institute under U.S.\r\nGovernment grant NAG W-2166.
  The images of these surveys are based on\r\nphotographic data obtained using the
  Oschin Schmidt Telescope on Palomar\r\nMountain and the UK Schmidt Telescope. The
  plates were processed into the\r\npresent compressed digital form with the permission
  of these institutions.\r\nThe National Geographic Society – Palomar Observatory
  Sky Atlas (POSS-I)\r\nwas made by the California Institute of Technology with grants
  from the\r\nNational Geographic Society. The Second Palomar Observatory Sky Survey\r\n(POSS-II)
  was made by the California Institute of Technology with funds\r\nfrom the National
  Science Foundation, the National Geographic Society, the\r\nSloan Foundation, the
  Samuel Oschin Foundation, and the Eastman Kodak\r\nCorporation. The Oschin Schmidt
  Telescope is operated by the California\r\nInstitute of Technology and Palomar Observatory.
  The UK Schmidt Telescope\r\nwas operated by the Royal Observatory Edinburgh, with
  funding from the\r\nUK Science and Engineering Research Council (later the UK Particle
  Physics\r\nand Astronomy Research Council), until 1988 June, and thereafter by the\r\nAnglo-Australian
  Observatory. The blue plates of the southern Sky Atlas\r\nand its Equatorial Extension
  (together known as the SERC-J), as well as the\r\nEquatorial Red (ER), and the Second
  Epoch [red] Survey (SES) were all taken\r\nwith the UK Schmidt. Supplemental funding
  for sky-survey work at the ST\r\nScI is provided by the European Southern Observatory.
  Based on observations\r\nobtained with the Samuel Oschin Telescope 48-inch and the
  60-inch Telescope\r\nat the Palomar Observatory as part of the Zwicky Transient
  Facility project.\r\nZTF is supported by the National Science Foundation under Grants
  No. AST-\r\n1440341 and AST-2034437 and a collaboration including current partners\r\nCaltech,
  IPAC, the Oskar Klein Center at Stockholm University, the University\r\nof Maryland,
  University of California, Berkeley, the University of Wisconsin\r\nat Milwaukee,
  University of Warwick, Ruhr University, Cornell University,\r\nNorthwestern University,
  and Drexel University. Operations are conducted\r\nby COO, IPAC, and UW. This work
  has used data from the European\r\nSpace Agency (ESA) mission Gaia (https://www.cosmos.esa.int/gaia),\r\nprocessed
  by the Gaia Data Processing and Analysis Consortium (DPAC,\r\nhttps://www.cosmos.esa.int/web/gaia/dpac/consortium).
  Funding for the\r\nDPAC has been provided by national institutions, in particular,
  the institutions\r\nparticipating in the Gaia Multilateral Agreement. We acknowledge
  with\r\nthanks the variable star observations from the AAVSO International Database\r\ncontributed
  by observers worldwide and used in this research. This paper\r\nincludes data collected
  by the TESS mission. Funding for the TESS mission\r\nis provided by the NASA Science
  Mission Directorate. Some of the data\r\npresented in this paper were obtained from
  the B. Mikulski Archive for Space\r\nTelescopes (MAST). This research has made use
  of the SIMBAD database,\r\noperated at CDS, Strasbourg, France. This research has
  made use of ‘Aladin\r\nsky atlas’ developed at CDS, Strasbourg Observatory, France.
  This research\r\nhas made use of the VizieR catalogue access tool, CDS, Strasbourg,
  France."
article_number: e052
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Jan
  full_name: Kára, Jan
  last_name: Kára
- first_name: Liliana
  full_name: Rivera Sandoval, Liliana
  last_name: Rivera Sandoval
- first_name: Wendy
  full_name: Mendoza, Wendy
  last_name: Mendoza
- first_name: Thomas
  full_name: Maccarone, Thomas
  last_name: Maccarone
- first_name: Manuel
  full_name: Pichardo Marcano, Manuel
  last_name: Pichardo Marcano
- first_name: Luis E.
  full_name: Salazar Manzano, Luis E.
  last_name: Salazar Manzano
- first_name: Ryan J.
  full_name: Oelkers, Ryan J.
  last_name: Oelkers
- first_name: Joannes C
  full_name: van Roestel, Joannes C
  id: 4d122fc8-6083-11f0-87a5-97d68b860333
  last_name: van Roestel
citation:
  ama: Kára J, Rivera Sandoval L, Mendoza W, et al. A study of transients from ground-based
    surveys reveals new ultra-compact accreting white dwarf binaries. <i>Publications
    of the Astronomical Society of Australia</i>. 2026;43. doi:<a href="https://doi.org/10.1017/pasa.2026.10184">10.1017/pasa.2026.10184</a>
  apa: Kára, J., Rivera Sandoval, L., Mendoza, W., Maccarone, T., Pichardo Marcano,
    M., Salazar Manzano, L. E., … van Roestel, J. C. (2026). A study of transients
    from ground-based surveys reveals new ultra-compact accreting white dwarf binaries.
    <i>Publications of the Astronomical Society of Australia</i>. Cambridge University
    Press. <a href="https://doi.org/10.1017/pasa.2026.10184">https://doi.org/10.1017/pasa.2026.10184</a>
  chicago: Kára, Jan, Liliana Rivera Sandoval, Wendy Mendoza, Thomas Maccarone, Manuel
    Pichardo Marcano, Luis E. Salazar Manzano, Ryan J. Oelkers, and Joannes C van
    Roestel. “A Study of Transients from Ground-Based Surveys Reveals New Ultra-Compact
    Accreting White Dwarf Binaries.” <i>Publications of the Astronomical Society of
    Australia</i>. Cambridge University Press, 2026. <a href="https://doi.org/10.1017/pasa.2026.10184">https://doi.org/10.1017/pasa.2026.10184</a>.
  ieee: J. Kára <i>et al.</i>, “A study of transients from ground-based surveys reveals
    new ultra-compact accreting white dwarf binaries,” <i>Publications of the Astronomical
    Society of Australia</i>, vol. 43. Cambridge University Press, 2026.
  ista: Kára J, Rivera Sandoval L, Mendoza W, Maccarone T, Pichardo Marcano M, Salazar
    Manzano LE, Oelkers RJ, van Roestel JC. 2026. A study of transients from ground-based
    surveys reveals new ultra-compact accreting white dwarf binaries. Publications
    of the Astronomical Society of Australia. 43, e052.
  mla: Kára, Jan, et al. “A Study of Transients from Ground-Based Surveys Reveals
    New Ultra-Compact Accreting White Dwarf Binaries.” <i>Publications of the Astronomical
    Society of Australia</i>, vol. 43, e052, Cambridge University Press, 2026, doi:<a
    href="https://doi.org/10.1017/pasa.2026.10184">10.1017/pasa.2026.10184</a>.
  short: J. Kára, L. Rivera Sandoval, W. Mendoza, T. Maccarone, M. Pichardo Marcano,
    L.E. Salazar Manzano, R.J. Oelkers, J.C. van Roestel, Publications of the Astronomical
    Society of Australia 43 (2026).
date_created: 2026-05-07T08:55:00Z
date_published: 2026-03-27T00:00:00Z
date_updated: 2026-05-12T06:57:40Z
day: '27'
ddc:
- '520'
department:
- _id: IlCa
doi: 10.1017/pasa.2026.10184
file:
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  file_id: '21862'
  file_name: 2026_PublAstronomicalSocAustralia_Kara.pdf
  file_size: 3681016
  relation: main_file
  success: 1
file_date_updated: 2026-05-12T06:54:10Z
has_accepted_license: '1'
intvolume: '        43'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
publication: Publications of the Astronomical Society of Australia
publication_identifier:
  eissn:
  - 1448-6083
  issn:
  - 1323-3580
publication_status: published
publisher: Cambridge University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: A study of transients from ground-based surveys reveals new ultra-compact accreting
  white dwarf binaries
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 43
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...
