--- OA_place: publisher OA_type: hybrid _id: '18479' abstract: - lang: eng text: The dominance of beneficial mutations is a key evolutionary parameter affecting the rate and genetic basis of adaptation, yet it is notoriously difficult to estimate. A leading method to infer it is to compare the relative rates of adaptive substitution for X-linked and autosomal genes, which—according to a classic model by Charlesworth et al. (1987)—is a simple function of the dominance of new beneficial mutations. Recent evidence that rates of adaptive substitution are faster for X-linked genes implies, accordingly, that beneficial mutations are usually recessive. However, this conclusion is incompatible with leading theories of dominance, which predict that beneficial mutations tend to be dominant or overdominant with respect to fitness. To address this incompatibility, we use Fisher’s geometric model to predict the distribution of fitness effects of new mutations and the relative rates of positively selected substitution on the X and autosomes. Previous predictions of faster-X theory emerge as a special case of our model in which the phenotypic effects of mutations are small relative to the distance to the phenotypic optimum. But as mutational effects become large relative to the optimum, we observe an elevated tempo of positively selected substitutions on the X relative to the autosomes across a broader range of dominance conditions, including those predicted by theories of dominance. Our results imply that, contrary to previous models, dominant and overdominant beneficial mutations can plausibly generate patterns of faster-X adaptation. We discuss resulting implications for genomic studies of adaptation and inferences of dominance. acknowledgement: This work was supported by funds from the Australian Research Council and The School of Biological Sciences at Monash University. F.R. was funded by a H2020 Marie Skłodowska-Curie COFUND Action (No. 101034413). We thank three anonymous reviewers for suggestions that substantially improved the paper and breadth of the analysis. article_number: e2406335121 article_processing_charge: Yes (in subscription journal) article_type: original author: - first_name: Yasmine full_name: Mcdonough, Yasmine last_name: Mcdonough - first_name: Filip full_name: Ruzicka, Filip id: 347955dd-57b0-11ee-9095-c28bdd368f4b last_name: Ruzicka - first_name: Tim full_name: Connallon, Tim last_name: Connallon citation: ama: Mcdonough Y, Ruzicka F, Connallon T. Reconciling theories of dominance with the relative rates of adaptive substitution on sex chromosomes and autosomes. Proceedings of the National Academy of Sciences of the United States of America. 2024;121(44). doi:10.1073/pnas.2406335121 apa: Mcdonough, Y., Ruzicka, F., & Connallon, T. (2024). Reconciling theories of dominance with the relative rates of adaptive substitution on sex chromosomes and autosomes. Proceedings of the National Academy of Sciences of the United States of America. National Academy of Sciences. https://doi.org/10.1073/pnas.2406335121 chicago: Mcdonough, Yasmine, Filip Ruzicka, and Tim Connallon. “Reconciling Theories of Dominance with the Relative Rates of Adaptive Substitution on Sex Chromosomes and Autosomes.” Proceedings of the National Academy of Sciences of the United States of America. National Academy of Sciences, 2024. https://doi.org/10.1073/pnas.2406335121. ieee: Y. Mcdonough, F. Ruzicka, and T. Connallon, “Reconciling theories of dominance with the relative rates of adaptive substitution on sex chromosomes and autosomes,” Proceedings of the National Academy of Sciences of the United States of America, vol. 121, no. 44. National Academy of Sciences, 2024. ista: Mcdonough Y, Ruzicka F, Connallon T. 2024. Reconciling theories of dominance with the relative rates of adaptive substitution on sex chromosomes and autosomes. Proceedings of the National Academy of Sciences of the United States of America. 121(44), e2406335121. mla: Mcdonough, Yasmine, et al. “Reconciling Theories of Dominance with the Relative Rates of Adaptive Substitution on Sex Chromosomes and Autosomes.” Proceedings of the National Academy of Sciences of the United States of America, vol. 121, no. 44, e2406335121, National Academy of Sciences, 2024, doi:10.1073/pnas.2406335121. short: Y. Mcdonough, F. Ruzicka, T. Connallon, Proceedings of the National Academy of Sciences of the United States of America 121 (2024). date_created: 2024-10-27T23:01:44Z date_published: 2024-10-29T00:00:00Z date_updated: 2025-09-08T14:31:58Z day: '29' ddc: - '570' department: - _id: BeVi doi: 10.1073/pnas.2406335121 ec_funded: 1 external_id: isi: - '001359216400017' pmid: - '39436652' file: - access_level: open_access checksum: 73db3c87b35753e0f4324417f164a35e content_type: application/pdf creator: dernst date_created: 2024-11-04T10:29:43Z date_updated: 2024-11-04T10:29:43Z file_id: '18501' file_name: 2024_PNAS_McDonough.pdf file_size: 1299095 relation: main_file success: 1 file_date_updated: 2024-11-04T10:29:43Z has_accepted_license: '1' intvolume: ' 121' isi: 1 issue: '44' language: - iso: eng license: https://creativecommons.org/licenses/by-nc-nd/4.0/ month: '10' oa: 1 oa_version: Published Version pmid: 1 project: - _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c call_identifier: H2020 grant_number: '101034413' name: 'IST-BRIDGE: International postdoctoral program' publication: Proceedings of the National Academy of Sciences of the United States of America publication_identifier: eissn: - 1091-6490 publication_status: published publisher: National Academy of Sciences quality_controlled: '1' scopus_import: '1' status: public title: Reconciling theories of dominance with the relative rates of adaptive substitution on sex chromosomes and autosomes tmp: image: /images/cc_by_nc_nd.png legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) short: CC BY-NC-ND (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 121 year: '2024' ... --- DOAJ_listed: '1' OA_place: publisher OA_type: gold _id: '18480' abstract: - lang: eng text: Caloric restriction (CR) can extend the organism life- and health-span by improving glucose homeostasis. How CR affects the structure-function of pancreatic beta cells remains unknown. We used single nucleus transcriptomics to show that CR increases the expression of genes for beta cell identity, protein processing, and organelle homeostasis. Gene regulatory network analysis reveal that CR activates transcription factors important for beta cell identity and homeostasis, while imaging metabolomics demonstrates that beta cells upon CR are more energetically competent. In fact, high-resolution microscopy show that CR reduces beta cell mitophagy to increase mitochondria mass and the potential for ATP generation. However, CR beta cells have impaired adaptive proliferation in response to high fat diet feeding. Finally, we show that long-term CR delays the onset of beta cell aging hallmarks and promotes cell longevity by reducing beta cell turnover. Therefore, CR could be a feasible approach to preserve compromised beta cell structure-function during aging and diabetes. acknowledgement: We are thankful to Michelle Reyzer from the Vanderbilt Mass Spectrometry Research Center for assistance with MALDI-MS imaging and analysis, to the outstanding team at the Vanderbilt Mouse Metabolic Phenotyping Center for all the assistance with in vivo glucose homeostasis tests (DK135073, 1S10RR028101-01). We also thank the University of Michigan Animal Phenotyping Core for conducting the bomb calorimetry experiments (1U2CDK110768, DK020575, and DK089503). This research was supported by recruitment funds from the Vanderbilt’s Department of Molecular Physiology and Biophysics and NIH grants 1R03DK127484, 5U24DK097771, and 1R01DK138141 to RAeD, by a grant from the Canadian Institutes of Health Research (CIHR; 487188) to PEM, by and NIH DK132669 to D.D. PEM holds the Canada Research Chair in Islet Biology. article_number: '9063' article_processing_charge: Yes article_type: original author: - first_name: Cristiane full_name: Dos Santos, Cristiane last_name: Dos Santos - first_name: Amanda full_name: Cambraia, Amanda last_name: Cambraia - first_name: Shristi full_name: Shrestha, Shristi last_name: Shrestha - first_name: Melanie full_name: Cutler, Melanie last_name: Cutler - first_name: Matthew full_name: Cottam, Matthew last_name: Cottam - first_name: Guy full_name: Perkins, Guy last_name: Perkins - first_name: Varda full_name: Lev-Ram, Varda last_name: Lev-Ram - first_name: Birbickram full_name: Roy, Birbickram last_name: Roy - first_name: Christopher full_name: Acree, Christopher last_name: Acree - first_name: Keun Young full_name: Kim, Keun Young last_name: Kim - first_name: Thomas full_name: Deerinck, Thomas last_name: Deerinck - first_name: Danielle full_name: Dean, Danielle last_name: Dean - first_name: Jean Philippe full_name: Cartailler, Jean Philippe last_name: Cartailler - first_name: Patrick E. full_name: Macdonald, Patrick E. last_name: Macdonald - first_name: Martin W full_name: Hetzer, Martin W id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed last_name: Hetzer orcid: 0000-0002-2111-992X - first_name: Mark full_name: Ellisman, Mark last_name: Ellisman - first_name: Rafael full_name: Arrojo E Drigo, Rafael last_name: Arrojo E Drigo citation: ama: Dos Santos C, Cambraia A, Shrestha S, et al. Calorie restriction increases insulin sensitivity to promote beta cell homeostasis and longevity in mice. Nature Communications. 2024;15. doi:10.1038/s41467-024-53127-2 apa: Dos Santos, C., Cambraia, A., Shrestha, S., Cutler, M., Cottam, M., Perkins, G., … Arrojo E Drigo, R. (2024). Calorie restriction increases insulin sensitivity to promote beta cell homeostasis and longevity in mice. Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-024-53127-2 chicago: Dos Santos, Cristiane, Amanda Cambraia, Shristi Shrestha, Melanie Cutler, Matthew Cottam, Guy Perkins, Varda Lev-Ram, et al. “Calorie Restriction Increases Insulin Sensitivity to Promote Beta Cell Homeostasis and Longevity in Mice.” Nature Communications. Springer Nature, 2024. https://doi.org/10.1038/s41467-024-53127-2. ieee: C. Dos Santos et al., “Calorie restriction increases insulin sensitivity to promote beta cell homeostasis and longevity in mice,” Nature Communications, vol. 15. Springer Nature, 2024. ista: Dos Santos C, Cambraia A, Shrestha S, Cutler M, Cottam M, Perkins G, Lev-Ram V, Roy B, Acree C, Kim KY, Deerinck T, Dean D, Cartailler JP, Macdonald PE, Hetzer M, Ellisman M, Arrojo E Drigo R. 2024. Calorie restriction increases insulin sensitivity to promote beta cell homeostasis and longevity in mice. Nature Communications. 15, 9063. mla: Dos Santos, Cristiane, et al. “Calorie Restriction Increases Insulin Sensitivity to Promote Beta Cell Homeostasis and Longevity in Mice.” Nature Communications, vol. 15, 9063, Springer Nature, 2024, doi:10.1038/s41467-024-53127-2. short: C. Dos Santos, A. Cambraia, S. Shrestha, M. Cutler, M. Cottam, G. Perkins, V. Lev-Ram, B. Roy, C. Acree, K.Y. Kim, T. Deerinck, D. Dean, J.P. Cartailler, P.E. Macdonald, M. Hetzer, M. Ellisman, R. Arrojo E Drigo, Nature Communications 15 (2024). date_created: 2024-10-27T23:01:44Z date_published: 2024-10-21T00:00:00Z date_updated: 2025-09-08T14:32:38Z day: '21' ddc: - '570' department: - _id: MaHe doi: 10.1038/s41467-024-53127-2 external_id: isi: - '001426270600023' pmid: - '39433757' file: - access_level: open_access checksum: b936b1c047f41cd427f00e3dc79327d3 content_type: application/pdf creator: dernst date_created: 2024-11-04T10:37:56Z date_updated: 2024-11-04T10:37:56Z file_id: '18502' file_name: 2024_NatureComm_dosSantos.pdf file_size: 7358742 relation: main_file success: 1 file_date_updated: 2024-11-04T10:37:56Z has_accepted_license: '1' intvolume: ' 15' isi: 1 language: - iso: eng month: '10' oa: 1 oa_version: Published Version pmid: 1 publication: Nature Communications publication_identifier: eissn: - 2041-1723 publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: Calorie restriction increases insulin sensitivity to promote beta cell homeostasis and longevity in mice tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 15 year: '2024' ... --- APC_amount: 3197,23 EUR DOAJ_listed: '1' OA_place: publisher OA_type: gold _id: '18481' abstract: - lang: eng text: A tight regulation of morphogen production is key for morphogen gradient formation and thereby for reproducible and organised organ development. Although many genetic interactions involved in the establishment of morphogen production domains are known, the biophysical mechanisms of morphogen source formation are poorly understood. Here we addressed this by focusing on the morphogen Sonic hedgehog (Shh) in the vertebrate neural tube. Shh is produced by the adjacently located notochord and by the floor plate of the neural tube. Using a data-constrained computational screen, we identified different possible mechanisms by which floor plate formation can occur, only one of which is consistent with experimental data. In this mechanism, the floor plate is established rapidly in response to Shh from the notochord and the dynamics of regulatory interactions within the neural tube. In this process, uniform activators and Shh-dependent repressors are key for establishing the floor plate size. Subsequently, the floor plate becomes insensitive to Shh and increases in size due to tissue growth, leading to scaling of the floor plate with neural tube size. In turn, this results in scaling of the Shh amplitude with tissue growth. Thus, this mechanism ensures a separation of time scales in floor plate formation, so that the floor plate domain becomes growth-dependent after an initial rapid establishment phase. Our study raises the possibility that the time scale separation between specification and growth might be a common strategy for scaling the morphogen gradient amplitude in growing organs. The model that we developed provides a new opportunity for quantitative studies of morphogen source formation in growing tissues. acknowledgement: "We thank Martina Greunz-Schindler for technical support, and Thomas Minchington and James Briscoe for comments on the manuscript.\r\nRDJGH, MM and MZ were supported by a grant from the Priority Research Area DigiWorld\r\nunder the Strategic Programme Excellence Initiative at Jagiellonian University. The research\r\nwas supported by the Polish National Agency for Academic Exchange, PN/PPO/2018/1/00011/U/00001 which paid the salary of MM and MZ up to Feb 2023. The research received support from National Science Center, Poland, 2021/42/E/NZ2/00188 which paid salary of MZ. Work in the AK labis supported by ISTA to KK and AK, the European\r\nResearch Council under Horizon Europe: grant 101044579 to AK, and Austrian Science Fund\r\n(FWF): Grant DOI 10.55776/F78 to AK. The salaries of AK and KK were paid by ISTA. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript." article_number: e1012508 article_processing_charge: No article_type: original author: - first_name: Richard D.J.G. full_name: Ho, Richard D.J.G. last_name: Ho - first_name: Kasumi full_name: Kishi, Kasumi id: 3065DFC4-F248-11E8-B48F-1D18A9856A87 last_name: Kishi orcid: 0000-0001-6060-4795 - first_name: Maciej full_name: Majka, Maciej last_name: Majka - first_name: Anna full_name: Kicheva, Anna id: 3959A2A0-F248-11E8-B48F-1D18A9856A87 last_name: Kicheva orcid: 0000-0003-4509-4998 - first_name: Marcin P full_name: Zagórski, Marcin P id: 343DA0DC-F248-11E8-B48F-1D18A9856A87 last_name: Zagórski orcid: 0000-0001-7896-7762 citation: ama: Ho RDJG, Kishi K, Majka M, Kicheva A, Zagórski MP. Dynamics of morphogen source formation in a growing tissue. PLoS Computational Biology. 2024;20. doi:10.1371/journal.pcbi.1012508 apa: Ho, R. D. J. G., Kishi, K., Majka, M., Kicheva, A., & Zagórski, M. P. (2024). Dynamics of morphogen source formation in a growing tissue. PLoS Computational Biology. Public Library of Science. https://doi.org/10.1371/journal.pcbi.1012508 chicago: Ho, Richard D.J.G., Kasumi Kishi, Maciej Majka, Anna Kicheva, and Marcin P Zagórski. “Dynamics of Morphogen Source Formation in a Growing Tissue.” PLoS Computational Biology. Public Library of Science, 2024. https://doi.org/10.1371/journal.pcbi.1012508. ieee: R. D. J. G. Ho, K. Kishi, M. Majka, A. Kicheva, and M. P. Zagórski, “Dynamics of morphogen source formation in a growing tissue,” PLoS Computational Biology, vol. 20. Public Library of Science, 2024. ista: Ho RDJG, Kishi K, Majka M, Kicheva A, Zagórski MP. 2024. Dynamics of morphogen source formation in a growing tissue. PLoS Computational Biology. 20, e1012508. mla: Ho, Richard D. J. G., et al. “Dynamics of Morphogen Source Formation in a Growing Tissue.” PLoS Computational Biology, vol. 20, e1012508, Public Library of Science, 2024, doi:10.1371/journal.pcbi.1012508. short: R.D.J.G. Ho, K. Kishi, M. Majka, A. Kicheva, M.P. Zagórski, PLoS Computational Biology 20 (2024). corr_author: '1' date_created: 2024-10-27T23:01:45Z date_published: 2024-10-14T00:00:00Z date_updated: 2026-04-07T12:31:58Z day: '14' ddc: - '570' department: - _id: AnKi doi: 10.1371/journal.pcbi.1012508 external_id: isi: - '001331700300003' pmid: - '39401260' file: - access_level: open_access checksum: 42fa714459943cb3961b40fab8fd82c8 content_type: application/pdf creator: dernst date_created: 2024-10-29T11:59:09Z date_updated: 2024-10-29T11:59:09Z file_id: '18487' file_name: 2024_PloSComBio_Ho.pdf file_size: 3732443 relation: main_file success: 1 file_date_updated: 2024-10-29T11:59:09Z has_accepted_license: '1' intvolume: ' 20' isi: 1 language: - iso: eng month: '10' oa: 1 oa_version: Published Version pmid: 1 project: - _id: bd7e737f-d553-11ed-ba76-d69ffb5ee3aa grant_number: '101044579' name: Mechanisms of tissue size regulation in spinal cord development - _id: 059DF620-7A3F-11EA-A408-12923DDC885E grant_number: F7802 name: Stem Cell Modulation in Neural Development and Regeneration/ P02-Morphogen control of growth and pattern in the spinal cord publication: PLoS Computational Biology publication_identifier: eissn: - 1553-7358 issn: - 1553-734X publication_status: published publisher: Public Library of Science quality_controlled: '1' related_material: record: - id: '20393' relation: dissertation_contains status: public scopus_import: '1' status: public title: Dynamics of morphogen source formation in a growing tissue tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 20 year: '2024' ... --- OA_type: closed access _id: '18482' abstract: - lang: eng text: "This paper is dedicated to an optimization problem. Let A, B ⊂ Rn be compact convex sets. Consider the minimal number t0 > 0 such that t0B covers A after a shift to a vector x0 ∈ \r\nRn. The goal is to find t0 and x0. In the special case of B being a unit ball centered at zero, x0 and t0 are known as the Chebyshev center and the Chebyshev radius of A. This paper focuses on the case in which A and B are defined with their black-box support functions. An algorithm for solving such problems efficiently is suggested. The algorithm has a superlinear convergence rate, and it can solve hundred-dimensional test problems in a reasonable time, but some additional conditions on A and B are required to guarantee the presence of convergence. Additionally, the behavior of the algorithm for a simple special case is investigated, which leads to a number of theoretical results. Perturbations of this special case are also studied." acknowledgement: The author is grateful to Maxim Balashov for setting the problem, providing useful literature, important discussions and text review. Also, I thank Dmitry Tsarev and Kseniia Petukhova for meaningful talks and support. article_processing_charge: No article_type: original author: - first_name: Pavel full_name: Arkhipov, Pavel id: b25f2ab2-1fed-11ee-8599-fe02d211784f last_name: Arkhipov citation: ama: Arkhipov P. An algorithm for finding the generalized Chebyshev center of sets defined via their support functions. Automation and Remote Control. 2024;85(6):522-532. doi:10.1134/S0005117924060031 apa: Arkhipov, P. (2024). An algorithm for finding the generalized Chebyshev center of sets defined via their support functions. Automation and Remote Control. Springer Nature. https://doi.org/10.1134/S0005117924060031 chicago: Arkhipov, Pavel. “An Algorithm for Finding the Generalized Chebyshev Center of Sets Defined via Their Support Functions.” Automation and Remote Control. Springer Nature, 2024. https://doi.org/10.1134/S0005117924060031. ieee: P. Arkhipov, “An algorithm for finding the generalized Chebyshev center of sets defined via their support functions,” Automation and Remote Control, vol. 85, no. 6. Springer Nature, pp. 522–532, 2024. ista: Arkhipov P. 2024. An algorithm for finding the generalized Chebyshev center of sets defined via their support functions. Automation and Remote Control. 85(6), 522–532. mla: Arkhipov, Pavel. “An Algorithm for Finding the Generalized Chebyshev Center of Sets Defined via Their Support Functions.” Automation and Remote Control, vol. 85, no. 6, Springer Nature, 2024, pp. 522–32, doi:10.1134/S0005117924060031. short: P. Arkhipov, Automation and Remote Control 85 (2024) 522–532. corr_author: '1' date_created: 2024-10-27T23:01:45Z date_published: 2024-06-01T00:00:00Z date_updated: 2025-09-08T14:27:08Z day: '01' department: - _id: GradSch doi: 10.1134/S0005117924060031 external_id: isi: - '001338721700007' intvolume: ' 85' isi: 1 issue: '6' language: - iso: eng month: '06' oa_version: None page: 522-532 publication: Automation and Remote Control publication_identifier: eissn: - 1608-3032 issn: - 0005-1179 publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: An algorithm for finding the generalized Chebyshev center of sets defined via their support functions type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 85 year: '2024' ... --- OA_place: publisher OA_type: hybrid _id: '18483' abstract: - lang: eng text: In this paper we prove a perturbative version of a remarkable Bialy–Mironov (Ann. Math. 196(1):389–413, 2022) result. They prove non perturbative Birkhoff conjecture for centrally-symmetric convex domains, namely, a centrally-symmetric convex domain with integrable billiard is ellipse. We combine techniques from Bialy–Mironov (Ann. Math. 196(1):389–413, 2022) with a local result by Kaloshin–Sorrentino (Ann. Math. 188(1):315–380, 2018) and show that a domain close enough to a centrally symmetric one with integrable billiard is ellipse. To combine these results we derive a slight extension of Bialy–Mironov (Ann. Math. 196(1):389–413, 2022) by proving that a notion of rational integrability is equivalent to the C0-integrability condition used in their paper. acknowledgement: We are grateful to the anonymous referee for their careful reading and valuable remarks and comments which helped to improve significantly the paper. Open access funding provided by Institute of Science and Technology (IST Austria). V.K. and C.E.K. gratefully acknowledge support from the European Research Council (ERC) through the Advanced Grant “SPERIG” (#885 707). article_processing_charge: Yes (via OA deal) article_type: original arxiv: 1 author: - first_name: Vadim full_name: Kaloshin, Vadim id: FE553552-CDE8-11E9-B324-C0EBE5697425 last_name: Kaloshin orcid: 0000-0002-6051-2628 - first_name: Edmond full_name: Koudjinan, Edmond id: 52DF3E68-AEFA-11EA-95A4-124A3DDC885E last_name: Koudjinan orcid: 0000-0003-2640-4049 - first_name: Ke full_name: Zhang, Ke last_name: Zhang citation: ama: Kaloshin V, Koudjinan E, Zhang K. Birkhoff conjecture for nearly centrally symmetric domains. Geometric and Functional Analysis. 2024;34:1973-2007. doi:10.1007/s00039-024-00695-6 apa: Kaloshin, V., Koudjinan, E., & Zhang, K. (2024). Birkhoff conjecture for nearly centrally symmetric domains. Geometric and Functional Analysis. Springer Nature. https://doi.org/10.1007/s00039-024-00695-6 chicago: Kaloshin, Vadim, Edmond Koudjinan, and Ke Zhang. “Birkhoff Conjecture for Nearly Centrally Symmetric Domains.” Geometric and Functional Analysis. Springer Nature, 2024. https://doi.org/10.1007/s00039-024-00695-6. ieee: V. Kaloshin, E. Koudjinan, and K. Zhang, “Birkhoff conjecture for nearly centrally symmetric domains,” Geometric and Functional Analysis, vol. 34. Springer Nature, pp. 1973–2007, 2024. ista: Kaloshin V, Koudjinan E, Zhang K. 2024. Birkhoff conjecture for nearly centrally symmetric domains. Geometric and Functional Analysis. 34, 1973–2007. mla: Kaloshin, Vadim, et al. “Birkhoff Conjecture for Nearly Centrally Symmetric Domains.” Geometric and Functional Analysis, vol. 34, Springer Nature, 2024, pp. 1973–2007, doi:10.1007/s00039-024-00695-6. short: V. Kaloshin, E. Koudjinan, K. Zhang, Geometric and Functional Analysis 34 (2024) 1973–2007. corr_author: '1' date_created: 2024-10-27T23:01:45Z date_published: 2024-12-01T00:00:00Z date_updated: 2025-09-08T14:27:45Z day: '01' ddc: - '510' department: - _id: VaKa doi: 10.1007/s00039-024-00695-6 ec_funded: 1 external_id: arxiv: - '2306.12301' isi: - '001329804200001' file: - access_level: open_access checksum: e7fcd9f78beb40408c7d858ac0625e27 content_type: application/pdf creator: dernst date_created: 2025-01-13T09:14:24Z date_updated: 2025-01-13T09:14:24Z file_id: '18833' file_name: 2024_GeometricFunctionalAnalysis_Kaloshin.pdf file_size: 2260980 relation: main_file success: 1 file_date_updated: 2025-01-13T09:14:24Z has_accepted_license: '1' intvolume: ' 34' isi: 1 language: - iso: eng month: '12' oa: 1 oa_version: Published Version page: 1973-2007 project: - _id: 9B8B92DE-BA93-11EA-9121-9846C619BF3A call_identifier: H2020 grant_number: '885707' name: Spectral rigidity and integrability for billiards and geodesic flows publication: Geometric and Functional Analysis publication_identifier: eissn: - 1420-8970 issn: - 1016-443X publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: Birkhoff conjecture for nearly centrally symmetric domains tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 34 year: '2024' ... --- APC_amount: 3711,01 EUR DOAJ_listed: '1' OA_place: publisher OA_type: gold _id: '18488' abstract: - lang: eng text: The advancement of quantum simulators motivates the development of a theoretical framework to assist with efficient state preparation in quantum many-body systems. Generally, preparing a target entangled state via unitary evolution with time-dependent couplings is a challenging task and very little is known about the existence of solutions and their properties. In this work we develop a constructive approach for preparing matrix product states (MPS) via continuous unitary evolution. We provide an explicit construction of the operator that exactly implements the evolution of a given MPS along a specified direction in its tangent space. This operator can be written as a sum of local terms of finite range, yet it is in general non-Hermitian. Relying on the explicit construction of the non-Hermitian generator of the dynamics, we demonstrate the existence of a Hermitian sequence of operators that implements the desired MPS evolution with an error that decreases exponentially with the operator range. The construction is benchmarked on an explicit periodic trajectory in a translationally invariant MPS manifold. We demonstrate that the Floquet unitary generating the dynamics over one period of the trajectory features an approximate MPS-like eigenstate embedded among a sea of thermalizing eigenstates. These results show that our construction is not only useful for state preparation and control of many-body systems, but also provides a generic route towards Floquet scars—periodically driven models with quasilocal generators of dynamics that have exact MPS eigenstates in their spectrum. acknowledgement: We thank L. Piroli, S. Garratt, and A. Molnár for insightful discussions. This research was funded in part by the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (Grant Agreements No. 850899 and No. 863476), the Austrian Science Fund (FWF) (Grant DOIs 10.55776/COE1, 10.55776/P36305, and 10.55776/F71), and the European Union (NextGenerationEU). This work was performed in part at the Aspen Center for Physics, which is supported by National Science Foundation Grant PHY-2210452. This research was supported in part by NSF Grant PHY-2309135 to the Kavli Institute for Theoretical Physics (KITP). article_number: '040311' article_processing_charge: Yes article_type: original arxiv: 1 author: - first_name: Marko full_name: Ljubotina, Marko id: F75EE9BE-5C90-11EA-905D-16643DDC885E last_name: Ljubotina orcid: 0000-0003-0038-7068 - first_name: Elena full_name: Petrova, Elena id: 0ac84990-897b-11ed-a09c-f5abb56a4ede last_name: Petrova - first_name: Norbert full_name: Schuch, Norbert last_name: Schuch - first_name: Maksym full_name: Serbyn, Maksym id: 47809E7E-F248-11E8-B48F-1D18A9856A87 last_name: Serbyn orcid: 0000-0002-2399-5827 citation: ama: Ljubotina M, Petrova E, Schuch N, Serbyn M. Tangent space generators of matrix product states and exact floquet quantum scars. PRX Quantum. 2024;5(4). doi:10.1103/prxquantum.5.040311 apa: Ljubotina, M., Petrova, E., Schuch, N., & Serbyn, M. (2024). Tangent space generators of matrix product states and exact floquet quantum scars. PRX Quantum. American Physical Society. https://doi.org/10.1103/prxquantum.5.040311 chicago: Ljubotina, Marko, Elena Petrova, Norbert Schuch, and Maksym Serbyn. “Tangent Space Generators of Matrix Product States and Exact Floquet Quantum Scars.” PRX Quantum. American Physical Society, 2024. https://doi.org/10.1103/prxquantum.5.040311. ieee: M. Ljubotina, E. Petrova, N. Schuch, and M. Serbyn, “Tangent space generators of matrix product states and exact floquet quantum scars,” PRX Quantum, vol. 5, no. 4. American Physical Society, 2024. ista: Ljubotina M, Petrova E, Schuch N, Serbyn M. 2024. Tangent space generators of matrix product states and exact floquet quantum scars. PRX Quantum. 5(4), 040311. mla: Ljubotina, Marko, et al. “Tangent Space Generators of Matrix Product States and Exact Floquet Quantum Scars.” PRX Quantum, vol. 5, no. 4, 040311, American Physical Society, 2024, doi:10.1103/prxquantum.5.040311. short: M. Ljubotina, E. Petrova, N. Schuch, M. Serbyn, PRX Quantum 5 (2024). corr_author: '1' date_created: 2024-10-29T16:04:05Z date_published: 2024-10-23T00:00:00Z date_updated: 2025-09-08T14:26:29Z day: '23' ddc: - '530' department: - _id: MaSe doi: 10.1103/prxquantum.5.040311 ec_funded: 1 external_id: arxiv: - '2403.12325' isi: - '001346198800001' file: - access_level: open_access checksum: 2e057ba021744d0a74602517935326b3 content_type: application/pdf creator: dernst date_created: 2024-10-30T08:59:09Z date_updated: 2024-10-30T08:59:09Z file_id: '18489' file_name: 2024_PRXQuantum_Ljubotina.pdf file_size: 1151431 relation: main_file success: 1 file_date_updated: 2024-10-30T08:59:09Z has_accepted_license: '1' intvolume: ' 5' isi: 1 issue: '4' language: - iso: eng month: '10' oa: 1 oa_version: Published Version project: - _id: 23841C26-32DE-11EA-91FC-C7463DDC885E call_identifier: H2020 grant_number: '850899' name: 'Non-Ergodic Quantum Matter: Universality, Dynamics and Control' publication: PRX Quantum publication_identifier: eissn: - 2691-3399 publication_status: published publisher: American Physical Society quality_controlled: '1' scopus_import: '1' status: public title: Tangent space generators of matrix product states and exact floquet quantum scars tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 5 year: '2024' ... --- OA_place: publisher OA_type: hybrid _id: '18490' abstract: - lang: eng text: 'For large classes of even-dimensional Riemannian manifolds (Formula presented.), we construct and analyze conformally invariant random fields. These centered Gaussian fields (Formula presented.), called co-polyharmonic Gaussian fields, are characterized by their covariance kernels k which exhibit a precise logarithmic divergence: (Formula presented.). They share a fundamental quasi-invariance property under conformal transformations. In terms of the co-polyharmonic Gaussian field (Formula presented.), we define the Liouville Quantum Gravity measure, a random measure on (Formula presented.), heuristically given as (Formula presented.) and rigorously obtained as almost sure weak limit of the right-hand side with (Formula presented.) replaced by suitable regular approximations (Formula presented.). In terms on the Liouville Quantum Gravity measure, we define the Liouville Brownian motion on (Formula presented.) and the random GJMS operators. Finally, we present an approach to a conformal field theory in arbitrary even dimension with an ansatz based on Branson''s (Formula presented.) -curvature: we give a rigorous meaning to the Polyakov–Liouville measure (Formula presented.) and we derive the corresponding conformal anomaly. The set of admissible manifolds is conformally invariant. It includes all compact 2-dimensional Riemannian manifolds, all compact non-negatively curved Einstein manifolds of even dimension, and large classes of compact hyperbolic manifolds of even dimension. However, not every compact even-dimensional Riemannian manifold is admissible. Our results concerning the logarithmic divergence of the kernel (Formula presented.) rely on new sharp estimates for heat kernels and higher order Green kernels on arbitrary closed manifolds. ' acknowledgement: The authors are grateful to Masha Gordina for helpful references, and to Nathanaël Berestycki, Baptiste Cerclé, and Ewain Gwynne for valuable comments on the first circulated version of this paper. They also would like to thank Sebastian Andres, Peter Friz, and Yizheng Yuan for pointing out an erroneous formulation in the previous version of Theorem 5.7. Moreover, KTS would liketo express his thanks to Sebastian Andres, Matthias Erbar, Martin Huesmann, and Jan Mass for stimulating discussions on previous attempts to this project. LDS gratefully acknowledges financial support from the European Research Council (grant agreement No 716117, awarded to J. Maas), from the Austrian Science Fund (FWF) project 10.55776/ESP208, and from the Austrian Science Fund (FWF) project 10.55776/F65.RH, EK, and KTS gratefully acknowledge funding by the Deutsche Forschungsgemeinschaft through the project “Random Riemannian Geometry” within the SPP 2265 “Random Geomet-ric Systems,” through the Hausdorff Center for Mathematics (project ID 390685813), and through project B03 within the CRC 1060 (project ID 211504053). RH and KTS also gratefully acknowledge financial support from the European Research Council through the ERC AdG “RicciBounds”(grant agreement 694405).Data sharing not applicable to this article as no datasets were generated or analyzed during the current study. Open access funding enabled and organized by Projekt DEAL. article_number: e70003 article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Lorenzo full_name: Dello Schiavo, Lorenzo id: ECEBF480-9E4F-11EA-B557-B0823DDC885E last_name: Dello Schiavo orcid: 0000-0002-9881-6870 - first_name: Ronan full_name: Herry, Ronan last_name: Herry - first_name: Eva full_name: Kopfer, Eva last_name: Kopfer - first_name: Karl Theodor full_name: Sturm, Karl Theodor last_name: Sturm citation: ama: Dello Schiavo L, Herry R, Kopfer E, Sturm KT. Conformally invariant random fields, Liouville quantum gravity measures, and random Paneitz operators on Riemannian manifolds of even dimension. Journal of the London Mathematical Society. 2024;110(5). doi:10.1112/jlms.70003 apa: Dello Schiavo, L., Herry, R., Kopfer, E., & Sturm, K. T. (2024). Conformally invariant random fields, Liouville quantum gravity measures, and random Paneitz operators on Riemannian manifolds of even dimension. Journal of the London Mathematical Society. London Mathematical Society. https://doi.org/10.1112/jlms.70003 chicago: Dello Schiavo, Lorenzo, Ronan Herry, Eva Kopfer, and Karl Theodor Sturm. “Conformally Invariant Random Fields, Liouville Quantum Gravity Measures, and Random Paneitz Operators on Riemannian Manifolds of Even Dimension.” Journal of the London Mathematical Society. London Mathematical Society, 2024. https://doi.org/10.1112/jlms.70003. ieee: L. Dello Schiavo, R. Herry, E. Kopfer, and K. T. Sturm, “Conformally invariant random fields, Liouville quantum gravity measures, and random Paneitz operators on Riemannian manifolds of even dimension,” Journal of the London Mathematical Society, vol. 110, no. 5. London Mathematical Society, 2024. ista: Dello Schiavo L, Herry R, Kopfer E, Sturm KT. 2024. Conformally invariant random fields, Liouville quantum gravity measures, and random Paneitz operators on Riemannian manifolds of even dimension. Journal of the London Mathematical Society. 110(5), e70003. mla: Dello Schiavo, Lorenzo, et al. “Conformally Invariant Random Fields, Liouville Quantum Gravity Measures, and Random Paneitz Operators on Riemannian Manifolds of Even Dimension.” Journal of the London Mathematical Society, vol. 110, no. 5, e70003, London Mathematical Society, 2024, doi:10.1112/jlms.70003. short: L. Dello Schiavo, R. Herry, E. Kopfer, K.T. Sturm, Journal of the London Mathematical Society 110 (2024). date_created: 2024-11-03T23:01:44Z date_published: 2024-11-01T00:00:00Z date_updated: 2025-09-08T14:29:45Z day: '01' ddc: - '510' department: - _id: JaMa doi: 10.1112/jlms.70003 ec_funded: 1 external_id: isi: - '001351918100029' file: - access_level: open_access checksum: 143816823b5f43bd3748da8e3e91cef5 content_type: application/pdf creator: dernst date_created: 2024-11-04T08:54:26Z date_updated: 2024-11-04T08:54:26Z file_id: '18497' file_name: 2024_JourLondonMathSoc_Schiavo.pdf file_size: 911476 relation: main_file success: 1 file_date_updated: 2024-11-04T08:54:26Z has_accepted_license: '1' intvolume: ' 110' isi: 1 issue: '5' language: - iso: eng month: '11' oa: 1 oa_version: Published Version project: - _id: 256E75B8-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '716117' name: Optimal Transport and Stochastic Dynamics - _id: 34dbf174-11ca-11ed-8bc3-afe9d43d4b9c grant_number: E208 name: Configuration Spaces over Non-Smooth Spaces - _id: fc31cba2-9c52-11eb-aca3-ff467d239cd2 grant_number: F6504 name: Taming Complexity in Partial Differential Systems publication: Journal of the London Mathematical Society publication_identifier: eissn: - 1469-7750 issn: - 0024-6107 publication_status: published publisher: London Mathematical Society quality_controlled: '1' scopus_import: '1' status: public title: Conformally invariant random fields, Liouville quantum gravity measures, and random Paneitz operators on Riemannian manifolds of even dimension tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 110 year: '2024' ... --- APC_amount: 4569,23 EUR DOAJ_listed: '1' OA_place: publisher OA_type: gold PlanS_conform: '1' _id: '18491' abstract: - lang: eng text: Predicting the outcomes of adaptation is a major goal of evolutionary biology. When temporal changes in the environment mirror spatial gradients, it opens up the potential for predicting the course of adaptive evolution over time based on patterns of spatial genetic and phenotypic variation. We assessed this approach in a 30-year transplant experiment in the intertidal snail Littorina saxatilis. In 1992, snails were transplanted from a predation-dominated environment to one dominated by wave action. On the basis of spatial patterns, we predicted transitions in shell size and morphology, allele frequencies at positions throughout the genome, and chromosomal rearrangement frequencies. Observed changes closely agreed with predictions and transformation was both dramatic and rapid. Hence, adaptation can be predicted from knowledge of the phenotypic and genetic variation among populations. acknowledgement: 'This work was received funding from the following: Norwegian Research Council RCN project 315287 (A.M.W.), Swedish Research Council 2021-04191 (K.J.), European Research Council grant 101055327 HaplotypeStructure (N.B.), Austrian Science Fund FWF; P 32166-B32 Snapdragon Speciation (N.B.), European Research Council (R.B.), and Portuguese Foundation for Science and Technology FCT: 2020.00275.CEECIND and PTDC/BIA-EVL/1614/2021 (R.F.).' article_number: eadp2102 article_processing_charge: Yes article_type: original author: - first_name: Diego Fernando full_name: Garcia Castillo, Diego Fernando id: ae681a14-dc74-11ea-a0a7-c6ef18161701 last_name: Garcia Castillo - first_name: Nicholas H full_name: Barton, Nicholas H id: 4880FE40-F248-11E8-B48F-1D18A9856A87 last_name: Barton orcid: 0000-0002-8548-5240 - first_name: Rui full_name: Faria, Rui last_name: Faria - first_name: Jenny full_name: Larsson, Jenny last_name: Larsson - first_name: Sean full_name: Stankowski, Sean id: 43161670-5719-11EA-8025-FABC3DDC885E last_name: Stankowski - first_name: Roger full_name: Butlin, Roger last_name: Butlin - first_name: Kerstin full_name: Johannesson, Kerstin last_name: Johannesson - first_name: Anja M full_name: Westram, Anja M id: 3C147470-F248-11E8-B48F-1D18A9856A87 last_name: Westram orcid: 0000-0003-1050-4969 citation: ama: 'Garcia Castillo DF, Barton NH, Faria R, et al. Predicting rapid adaptation in time from adaptation in space: A 30-year field experiment in marine snails. Science Advances. 2024;10(41). doi:10.1126/sciadv.adp2102' apa: 'Garcia Castillo, D. F., Barton, N. H., Faria, R., Larsson, J., Stankowski, S., Butlin, R., … Westram, A. M. (2024). Predicting rapid adaptation in time from adaptation in space: A 30-year field experiment in marine snails. Science Advances. AAAS. https://doi.org/10.1126/sciadv.adp2102' chicago: 'Garcia Castillo, Diego Fernando, Nicholas H Barton, Rui Faria, Jenny Larsson, Sean Stankowski, Roger Butlin, Kerstin Johannesson, and Anja M Westram. “Predicting Rapid Adaptation in Time from Adaptation in Space: A 30-Year Field Experiment in Marine Snails.” Science Advances. AAAS, 2024. https://doi.org/10.1126/sciadv.adp2102.' ieee: 'D. F. Garcia Castillo et al., “Predicting rapid adaptation in time from adaptation in space: A 30-year field experiment in marine snails,” Science Advances, vol. 10, no. 41. AAAS, 2024.' ista: 'Garcia Castillo DF, Barton NH, Faria R, Larsson J, Stankowski S, Butlin R, Johannesson K, Westram AM. 2024. Predicting rapid adaptation in time from adaptation in space: A 30-year field experiment in marine snails. Science Advances. 10(41), eadp2102.' mla: 'Garcia Castillo, Diego Fernando, et al. “Predicting Rapid Adaptation in Time from Adaptation in Space: A 30-Year Field Experiment in Marine Snails.” Science Advances, vol. 10, no. 41, eadp2102, AAAS, 2024, doi:10.1126/sciadv.adp2102.' short: D.F. Garcia Castillo, N.H. Barton, R. Faria, J. Larsson, S. Stankowski, R. Butlin, K. Johannesson, A.M. Westram, Science Advances 10 (2024). corr_author: '1' date_created: 2024-11-03T23:01:44Z date_published: 2024-10-11T00:00:00Z date_updated: 2026-04-07T11:42:09Z day: '11' ddc: - '570' department: - _id: NiBa doi: 10.1126/sciadv.adp2102 external_id: isi: - '001354405400018' file: - access_level: open_access checksum: 96aa0d3640fa9401975138e59054f84e content_type: application/pdf creator: dernst date_created: 2024-11-04T09:35:49Z date_updated: 2024-11-04T09:35:49Z file_id: '18499' file_name: 2024_ScienceAdv_Castillo.pdf file_size: 1154107 relation: main_file success: 1 file_date_updated: 2024-11-04T09:35:49Z has_accepted_license: '1' intvolume: ' 10' isi: 1 issue: '41' language: - iso: eng month: '10' oa: 1 oa_version: Published Version project: - _id: bd6958e0-d553-11ed-ba76-86eba6a76c00 grant_number: '101055327' name: Understanding the evolution of continuous genomes - _id: 05959E1C-7A3F-11EA-A408-12923DDC885E grant_number: P32166 name: Snapdragon Speciation - _id: 3AC91DDA-15DF-11EA-824D-93A3E7B544D1 call_identifier: FWF name: FWF Open Access Fund publication: Science Advances publication_identifier: eissn: - 2375-2548 publication_status: published publisher: AAAS quality_controlled: '1' related_material: link: - relation: software url: https://github.com/fernandoGarcia21/littorina_saxatilis_skerry record: - id: '18498' relation: research_data status: public - id: '20991' relation: dissertation_contains status: public scopus_import: '1' status: public title: 'Predicting rapid adaptation in time from adaptation in space: A 30-year field experiment in marine snails' tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 10 year: '2024' ... --- DOAJ_listed: '1' OA_place: publisher OA_type: gold _id: '18494' abstract: - lang: eng text: We expect luminous (M 1450 ≲ −26.5) high-redshift quasars to trace the highest-density peaks in the early Universe. Here, we present observations of four z ≳ 6 quasar fields using JWST/NIRCam in the imaging and wide-field slitless spectroscopy mode and report a wide range in the number of detected [O iii]-emitting galaxies in the quasars’ environments, ranging between a density enhancement of δ ≈ 65 within a 2 cMpc radius—one of the largest protoclusters during the Epoch of Reionization discovered to date—to a density contrast consistent with zero, indicating the presence of a UV-luminous quasar in a region comparable to the average density of the Universe. By measuring the two-point cross-correlation function of quasars and their surrounding galaxies, as well as the galaxy autocorrelation function, we infer a correlation length of quasars at 〈z〉 = 6.25 of r 0 QQ = 22.0 − 2.9 + 3.0 cMpc h − 1 , while we obtain a correlation length of the [O iii]-emitting galaxies of r 0 GG = 4.1 ± 0.3 cMpc h − 1 . By comparing the correlation functions to dark-matter-only simulations we estimate the minimum mass of the quasars’ host dark matter halos to be log 10 ( M halo , min / M ⊙ ) = 12.43 − 0.15 + 0.13 (and log 10 ( M halo , min [ OIII ] / M ⊙ ) = 10.56 − 0.03 + 0.05 for the [O iii] emitters), indicating that (a) luminous quasars do not necessarily reside within the most overdense regions in the early Universe, and that (b) the UV-luminous duty cycle of quasar activity at these redshifts is f duty ≪ 1. Such short quasar activity timescales challenge our understanding of early supermassive black hole growth and provide evidence for highly dust-obscured growth phases or episodic, radiatively inefficient accretion rates. acknowledgement: "The authors would like to thank the anonymous referee for the thoughtful comments, which significantly improved our manuscript, and Jan-Torge Schindler, Jiamu Huang, and Feige Wang for helpful discussions.\r\n\r\nJ.F.H. and E.P. acknowledge support from the European Research Council (ERC) under the European Unions Horizon 2020 research and innovation program (grant agreement No. 885301). J.M. acknowledges support from the European Union (ERC, AGENTS, 101076224).\r\n\r\nThis work is based on observations made with the NASA/ESA/CSA James Webb Space Telescope. The JWST data presented in this article were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. The specific observations analyzed are associated with program #1243 and can be accessed via doi:10.17909/m5mp-5v90.\r\n\r\nThis work used the DiRAC Memory Intensive service (Cosma8) at the University of Durham, which is part of the STFC DiRAC HPC Facility (www.dirac.ac.uk). Access to DiRAC resources was granted through a Directors Discretionary Time allocation in 2023/24, under the auspices of the UKRI-funded DiRAC Federation Project. The equipment was funded by BEIS capital funding via STFC capital grants ST/K00042X/1, ST/P002293/1, ST/R002371/1, and ST/S002502/1, Durham University and STFC operations grant ST/R000832/1. DiRAC is part of the National e-Infrastructure.\r\n\r\nWe thank the Instituto de Astrofisica de Andalucia (IAA-CSIC), Centro de Supercomputacion de Galicia (CESGA), and Spanish Academic and Research Network (RedIRIS) in Spain for hosting Uchuu DR1, DR2, and DR3 in the Skies & Universes site for cosmological simulations. The Uchuu simulations were carried out on the Aterui II supercomputer at the Center for Computational Astrophysics, CfCA, of the National Astronomical Observatory of Japan, and the K computer at the RIKEN Advanced Institute for Computational Science. The Uchuu Data Releases efforts have made use of the skunIAA_RedIRIS and skun6IAA computer facilities managed by the IAA-CSIC in Spain (MICINN EU-Feder grant EQC2018-004366-P)." article_number: '275' article_processing_charge: Yes article_type: original author: - first_name: Anna Christina full_name: Eilers, Anna Christina last_name: Eilers - first_name: Ruari full_name: Mackenzie, Ruari last_name: Mackenzie - first_name: Elia full_name: Pizzati, Elia last_name: Pizzati - first_name: Jorryt J full_name: Matthee, Jorryt J id: 7439a258-f3c0-11ec-9501-9df22fe06720 last_name: Matthee orcid: 0000-0003-2871-127X - first_name: Joseph F. full_name: Hennawi, Joseph F. last_name: Hennawi - first_name: Haowen full_name: Zhang, Haowen last_name: Zhang - first_name: Rongmon full_name: Bordoloi, Rongmon last_name: Bordoloi - first_name: Daichi full_name: Kashino, Daichi last_name: Kashino - first_name: Simon J. full_name: Lilly, Simon J. last_name: Lilly - first_name: Rohan P. full_name: Naidu, Rohan P. last_name: Naidu - first_name: Robert A. full_name: Simcoe, Robert A. last_name: Simcoe - first_name: Minghao full_name: Yue, Minghao last_name: Yue - first_name: Carlos S. full_name: Frenk, Carlos S. last_name: Frenk - first_name: John C. full_name: Helly, John C. last_name: Helly - first_name: Matthieu full_name: Schaller, Matthieu last_name: Schaller - first_name: Joop full_name: Schaye, Joop last_name: Schaye citation: ama: Eilers AC, Mackenzie R, Pizzati E, et al. EIGER. VI. The correlation function, host halo mass, and duty cycle of luminous quasars at z ≳ 6. Astrophysical Journal. 2024;974(2). doi:10.3847/1538-4357/ad778b apa: Eilers, A. C., Mackenzie, R., Pizzati, E., Matthee, J. J., Hennawi, J. F., Zhang, H., … Schaye, J. (2024). EIGER. VI. The correlation function, host halo mass, and duty cycle of luminous quasars at z ≳ 6. Astrophysical Journal. IOP Publishing. https://doi.org/10.3847/1538-4357/ad778b chicago: Eilers, Anna Christina, Ruari Mackenzie, Elia Pizzati, Jorryt J Matthee, Joseph F. Hennawi, Haowen Zhang, Rongmon Bordoloi, et al. “EIGER. VI. The Correlation Function, Host Halo Mass, and Duty Cycle of Luminous Quasars at z ≳ 6.” Astrophysical Journal. IOP Publishing, 2024. https://doi.org/10.3847/1538-4357/ad778b. ieee: A. C. Eilers et al., “EIGER. VI. The correlation function, host halo mass, and duty cycle of luminous quasars at z ≳ 6,” Astrophysical Journal, vol. 974, no. 2. IOP Publishing, 2024. ista: Eilers AC, Mackenzie R, Pizzati E, Matthee JJ, Hennawi JF, Zhang H, Bordoloi R, Kashino D, Lilly SJ, Naidu RP, Simcoe RA, Yue M, Frenk CS, Helly JC, Schaller M, Schaye J. 2024. EIGER. VI. The correlation function, host halo mass, and duty cycle of luminous quasars at z ≳ 6. Astrophysical Journal. 974(2), 275. mla: Eilers, Anna Christina, et al. “EIGER. VI. The Correlation Function, Host Halo Mass, and Duty Cycle of Luminous Quasars at z ≳ 6.” Astrophysical Journal, vol. 974, no. 2, 275, IOP Publishing, 2024, doi:10.3847/1538-4357/ad778b. short: A.C. Eilers, R. Mackenzie, E. Pizzati, J.J. Matthee, J.F. Hennawi, H. Zhang, R. Bordoloi, D. Kashino, S.J. Lilly, R.P. Naidu, R.A. Simcoe, M. Yue, C.S. Frenk, J.C. Helly, M. Schaller, J. Schaye, Astrophysical Journal 974 (2024). date_created: 2024-11-03T23:01:45Z date_published: 2024-10-01T00:00:00Z date_updated: 2025-09-08T14:29:05Z day: '01' ddc: - '520' department: - _id: JoMa doi: 10.3847/1538-4357/ad778b external_id: isi: - '001338877100001' file: - access_level: open_access checksum: 1fcac3d11d01d91cf2bb4963b6e10b22 content_type: application/pdf creator: dernst date_created: 2024-11-04T08:42:23Z date_updated: 2024-11-04T08:42:23Z file_id: '18496' file_name: 2024_AstrophysicalJour_Eilers.pdf file_size: 1042470 relation: main_file success: 1 file_date_updated: 2024-11-04T08:42:23Z has_accepted_license: '1' intvolume: ' 974' isi: 1 issue: '2' language: - iso: eng month: '10' oa: 1 oa_version: Published Version project: - _id: bd9b2118-d553-11ed-ba76-db24564edfea grant_number: '101076224' name: Young galaxies as tracers and agents of cosmic reionization publication: Astrophysical Journal publication_identifier: eissn: - 1538-4357 issn: - 0004-637X publication_status: published publisher: IOP Publishing quality_controlled: '1' scopus_import: '1' status: public title: EIGER. VI. The correlation function, host halo mass, and duty cycle of luminous quasars at z ≳ 6 tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 974 year: '2024' ... --- OA_place: repository _id: '18498' abstract: - lang: eng text: 'Scripts and data used in the research study Predicting rapid adaptation in time from adaptation in space: a 30-year field experiment in marine snails. https://doi.org/10.1101/2023.09.27.559715' article_processing_charge: No author: - first_name: Diego Fernando full_name: Garcia Castillo, Diego Fernando id: ae681a14-dc74-11ea-a0a7-c6ef18161701 last_name: Garcia Castillo - first_name: Nicholas H full_name: Barton, Nicholas H id: 4880FE40-F248-11E8-B48F-1D18A9856A87 last_name: Barton orcid: 0000-0002-8548-5240 - first_name: Rui full_name: Faria, Rui last_name: Faria - first_name: Jenny full_name: Larsson, Jenny last_name: Larsson - first_name: Sean full_name: Stankowski, Sean id: 43161670-5719-11EA-8025-FABC3DDC885E last_name: Stankowski - first_name: Roger full_name: Butlin, Roger last_name: Butlin - first_name: Kerstin full_name: Johannesson, Kerstin last_name: Johannesson - first_name: Anja M full_name: Westram, Anja M id: 3C147470-F248-11E8-B48F-1D18A9856A87 last_name: Westram orcid: 0000-0003-1050-4969 citation: ama: 'Garcia Castillo DF, Barton NH, Faria R, et al. Data and code for: Predicting rapid adaptation in time from adaptation in space: a 30-year field experiment in marine snails. 2024. doi:10.5281/ZENODO.12159343' apa: 'Garcia Castillo, D. F., Barton, N. H., Faria, R., Larsson, J., Stankowski, S., Butlin, R., … Westram, A. M. (2024). Data and code for: Predicting rapid adaptation in time from adaptation in space: a 30-year field experiment in marine snails. Zenodo. https://doi.org/10.5281/ZENODO.12159343' chicago: 'Garcia Castillo, Diego Fernando, Nicholas H Barton, Rui Faria, Jenny Larsson, Sean Stankowski, Roger Butlin, Kerstin Johannesson, and Anja M Westram. “Data and Code for: Predicting Rapid Adaptation in Time from Adaptation in Space: A 30-Year Field Experiment in Marine Snails.” Zenodo, 2024. https://doi.org/10.5281/ZENODO.12159343.' ieee: 'D. F. Garcia Castillo et al., “Data and code for: Predicting rapid adaptation in time from adaptation in space: a 30-year field experiment in marine snails.” Zenodo, 2024.' ista: 'Garcia Castillo DF, Barton NH, Faria R, Larsson J, Stankowski S, Butlin R, Johannesson K, Westram AM. 2024. Data and code for: Predicting rapid adaptation in time from adaptation in space: a 30-year field experiment in marine snails, Zenodo, 10.5281/ZENODO.12159343.' mla: 'Garcia Castillo, Diego Fernando, et al. Data and Code for: Predicting Rapid Adaptation in Time from Adaptation in Space: A 30-Year Field Experiment in Marine Snails. Zenodo, 2024, doi:10.5281/ZENODO.12159343.' short: D.F. Garcia Castillo, N.H. Barton, R. Faria, J. Larsson, S. Stankowski, R. Butlin, K. Johannesson, A.M. Westram, (2024). corr_author: '1' date_created: 2024-11-04T09:33:17Z date_published: 2024-06-19T00:00:00Z date_updated: 2026-04-16T12:20:37Z day: '19' ddc: - '570' department: - _id: NiBa doi: 10.5281/ZENODO.12159343 has_accepted_license: '1' main_file_link: - open_access: '1' url: https://doi.org/10.5281/zenodo.12159344 month: '06' oa: 1 oa_version: Published Version publisher: Zenodo related_material: record: - id: '20991' relation: used_in_publication status: public - id: '18491' relation: used_in_publication status: public status: public title: 'Data and code for: Predicting rapid adaptation in time from adaptation in space: a 30-year field experiment in marine snails' tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: research_data_reference user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2024' ... --- OA_place: repository OA_type: free access _id: '18503' abstract: - lang: eng text: "In 1996, Karger [Kar96] gave a startling randomized algorithm that finds a minimum-cut in a (weighted) graph in time O(m log3 n) which he termed near-linear time meaning linear (in the size of the input) times a polylogarthmic factor. In this paper, we give the first deterministic algorithm which runs in near-linear time for weighted graphs.\r\nPreviously, the breakthrough results of Kawarabayashi and Thorup [KT19] gave a near-linear time algorithm for simple graphs (which was improved to have running time O(m log2 n log log n) in [HRW20].) The main technique here is a clustering procedure that perfectly preserves minimum cuts. Recently, Li [Li21] gave an m1+o(1) deterministic minimum-cut algorithm for weighted graphs; this form of running time has been termed “almost-linear”. Li uses almost-linear time deterministic expander decompositions which do not perfectly preserve minimum cuts, but he can use these clusterings to, in a sense, “derandomize” the methods of Karger.\r\nIn terms of techniques, we provide a structural theorem that says there exists a sparse clustering that preserves minimum cuts in a weighted graph with o(1) error. In addition, we construct it deterministically in near linear time. This was done exactly for simple graphs in [KT19, HRW20] and with polylogarithmic error for weighted graphs in [Li21]. Extending the techniques in [KT19, HRW20] to weighted graphs presents significant challenges, and moreover, the algorithm can only polylogarithmically approximately preserve minimum cuts. A remaining challenge is to reduce the polylogarithmic-approximate clusterings to 1 + o(1/ log n)-approximate so that they can be applied recursively as in [Li21] over O(log n) many levels. This is an additional challenge that requires building on properties of tree-packings in the presence of a wide range of edge weights to, for example, find sources for local flow computations which identify minimum cuts that cross clusters." acknowledgement: This project has received funding from the European Research Council(ERC) under the European Union’s Horizon 2020 research and innovation programme (Grant agreement No. 101019564 “The Design of Modern Fully Dynamic Data Structures (MoDyn-Struct)” and the Austrian Science Fund (FWF) project Z 422-N, project “Static and Dynamic Hierarchical Graph Decompositions”, I 5982-N, and project “Fast Algorithms for a Reactive Network Layer (ReactNet)”, P33775-N, with additional funding from the netidee SCIENCE Stiftung, 2020–2024. article_processing_charge: No arxiv: 1 author: - first_name: Monika H full_name: Henzinger, Monika H id: 540c9bbd-f2de-11ec-812d-d04a5be85630 last_name: Henzinger orcid: 0000-0002-5008-6530 - first_name: Jason full_name: Li, Jason last_name: Li - first_name: Satish full_name: Rao, Satish last_name: Rao - first_name: Di full_name: Wang, Di last_name: Wang citation: ama: 'Henzinger M, Li J, Rao S, Wang D. Deterministic near-linear time minimum cut in weighted graphs. In: 35th Annual ACM-SIAM Symposium on Discrete Algorithms. Society for Industrial and Applied Mathematics; 2024:3089-3139. doi:10.1137/1.9781611977912.111' apa: 'Henzinger, M., Li, J., Rao, S., & Wang, D. (2024). Deterministic near-linear time minimum cut in weighted graphs. In 35th Annual ACM-SIAM Symposium on Discrete Algorithms (pp. 3089–3139). Alexandria, VA,  United States: Society for Industrial and Applied Mathematics. https://doi.org/10.1137/1.9781611977912.111' chicago: Henzinger, Monika, Jason Li, Satish Rao, and Di Wang. “Deterministic Near-Linear Time Minimum Cut in Weighted Graphs.” In 35th Annual ACM-SIAM Symposium on Discrete Algorithms, 3089–3139. Society for Industrial and Applied Mathematics, 2024. https://doi.org/10.1137/1.9781611977912.111. ieee: M. Henzinger, J. Li, S. Rao, and D. Wang, “Deterministic near-linear time minimum cut in weighted graphs,” in 35th Annual ACM-SIAM Symposium on Discrete Algorithms, Alexandria, VA,  United States, 2024, pp. 3089–3139. ista: 'Henzinger M, Li J, Rao S, Wang D. 2024. Deterministic near-linear time minimum cut in weighted graphs. 35th Annual ACM-SIAM Symposium on Discrete Algorithms. SODA: Symposium on Discrete Algorithms, 3089–3139.' mla: Henzinger, Monika, et al. “Deterministic Near-Linear Time Minimum Cut in Weighted Graphs.” 35th Annual ACM-SIAM Symposium on Discrete Algorithms, Society for Industrial and Applied Mathematics, 2024, pp. 3089–139, doi:10.1137/1.9781611977912.111. short: M. Henzinger, J. Li, S. Rao, D. Wang, in:, 35th Annual ACM-SIAM Symposium on Discrete Algorithms, Society for Industrial and Applied Mathematics, 2024, pp. 3089–3139. conference: end_date: 2024-01-10 location: Alexandria, VA, United States name: 'SODA: Symposium on Discrete Algorithms' start_date: 2024-01-07 corr_author: '1' date_created: 2024-11-04T10:54:21Z date_published: 2024-01-04T00:00:00Z date_updated: 2025-06-24T12:09:26Z day: '04' department: - _id: MoHe doi: 10.1137/1.9781611977912.111 ec_funded: 1 external_id: arxiv: - '2401.05627' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.48550/arXiv.2401.05627 month: '01' oa: 1 oa_version: Preprint page: 3089-3139 project: - _id: bd9ca328-d553-11ed-ba76-dc4f890cfe62 call_identifier: H2020 grant_number: '101019564' name: The design and evaluation of modern fully dynamic data structures - _id: 34def286-11ca-11ed-8bc3-da5948e1613c grant_number: Z00422 name: Efficient algorithms - _id: bda196b2-d553-11ed-ba76-8e8ee6c21103 grant_number: I05982 name: Static and Dynamic Hierarchical Graph Decompositions - _id: bd9e3a2e-d553-11ed-ba76-8aa684ce17fe grant_number: P33775 name: Fast Algorithms for a Reactive Network Layer publication: 35th Annual ACM-SIAM Symposium on Discrete Algorithms publication_identifier: eisbn: - '9781611977912' publication_status: published publisher: Society for Industrial and Applied Mathematics quality_controlled: '1' scopus_import: '1' status: public title: Deterministic near-linear time minimum cut in weighted graphs type: conference user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2024' ... --- OA_place: publisher OA_type: gold _id: '18515' abstract: - lang: eng text: "Understanding the role of evolutionary processes in shaping genetic variation has been a\r\nprimary goal in evolutionary genetics. In this regard, a key question is how genetically\r\ndistinct populations evolve in the face of gene flow, thereby generating genetic and\r\nphenotypic divergence and reproductive isolation (RI). This requires quantifying the role\r\nand relative contributions of prezygotic and postzygotic isolating mechanisms on the\r\nreduction of gene exchange between populations, and identifying regions in the genome\r\nthat mediate RI, which is often polygenic. Further, this needs distinguishing neutral and\r\nselected regions in the genome, and discerning how selection influences patterns of neutral\r\ndivergence.\r\nPopulation structure, defined as any deviation from panmixia, such as geographic distribution, movement and mating patterns of individuals, influences how genetic variation is\r\nstructured in space and shapes the neutral null model. Availability of large scale spatial\r\ngenomic datasets now enables us to detect signatures of population structure in genetic\r\ndata and infer population genetic parameters. Such inferences are crucial and have wide\r\napplications in biodiversity, conservation genetics, population management and medical\r\ngenetics. However, inferences are based on assumptions that do not always match the\r\ncomplex reality, thus leading to erroneous conclusions. Moreover, the role and interaction\r\nof heterogeneous population density and dispersal, which are ubiquitous in nature, has\r\nbeen challenging to study owing to their mathematical complexity. In such scenarios,\r\nfeedback between theory, data and simulations can prove to be useful.\r\nIn this thesis, I examine the effect of population structure on neutral genetic variation\r\nand barriers to gene exchange in hybridising populations, thereby bridging together the\r\nfields of spatial population genetics and speciation.\r\nDespite being a key concept in speciation, reproductive isolation (RI) lacks a quantitative\r\ndefinition and has been used and measured differently across different fields. Chapter 2\r\ngives a quantitative definition of RI, in terms of the effect of genetic differences on gene\r\nflow. We give analytical predictions for RI in a range of scenarios, in terms of effective migration rates for discrete populations and barrier strength for continuous populations.\r\nIn addition to this, we discuss current measures of RI and their limitations, and propose\r\nthe need for new measures that combine organismal and genetic perspectives of RI.\r\nIn chapter 3, I examine the combined effect of assortative mating, sexual selection\r\nand viability selection on RI. For this, we consider a polygenic ‘magic’ trait under a\r\nmainland-island model. We obtain novel theoretical predictions for molecular divergence\r\nin terms of effective migration rates, which bears a simple relationship to measurable\r\nfitness components of migrants and various early generation hybrids. We explore the\r\nconditions under which local adaptation can be maintained despite maladaptive gene flow\r\nand quantify the relative contributions of viability and sexual selection to genome-wide\r\nbarriers to gene flow.\r\nThe next two chapters of the thesis focus on a hybrid zone of Antirrhinum majus that\r\nconsist of two subspecies- the magenta flowered A. m. pseudomajus and the yellow\r\nflowered A.m. striatum. Previous studies have suggested that flower colour is target of\r\npollinator mediated selection and is influenced only by few genes. While these regions\r\nshow high genetic differentiation between the subspecies, the rest of the genome is seen\r\nto be well mixed. Chapter 4 examines the effects of heterogeneous population density\r\nand leptokurtic dispersal on isolation by distance and the distribution of heterozygosity\r\nby focusing on non-flower colour markers.\r\nChapter 5 analyses cline shapes and associations among 6 focal flower colour markers to\r\nunderstand how selection and dispersal maintain this hybrid zone. We see sharp coincident\r\nstepped clines at all loci and positive associations throughout the hybrid zone, contrary to\r\nthe expected patterns from diffusive gene flow. With a novel scheme of inferring dispersal\r\ncombined with multilocus simulations, we show that stepped clines do not reflect genetic\r\nbarriers to gene flow, but are rather a result of long-distance migration. This framework\r\nallows us to get realistic estimates gene flow and selection and shows how traditional cline\r\nanalysis may lead to inaccurate conclusions when assumptions of the theory are not met.\r\nOverall, this thesis investigates how different features of population structure leave\r\ndetectable signatures in genetic variation, namely in patterns of isolation by distance,\r\nlinkage disequilibrium and genetic divergence. It also highlights how effective migration\r\nrates provide useful way of analysing polygenic architectures and shed new light into\r\nhybrid zones. In doing so, I identify scenarios when simple models become insufficient\r\nand suggest possibe directions by combining genetic data with simulations." acknowledged_ssus: - _id: ScienComp acknowledgement: "I also acknowledge the funding agencies Marie Curie COFUND Doctoral Fellowship,\r\nAustrian Science Fund FWF (grant P32166) and ERC (grant PR1000ERC02) for financially\r\nsupporting my research over the years." alternative_title: - ISTA Thesis article_processing_charge: No author: - first_name: Parvathy full_name: Surendranadh, Parvathy id: 455235B8-F248-11E8-B48F-1D18A9856A87 last_name: Surendranadh orcid: 0000-0001-6395-386X citation: ama: Surendranadh P. Effect of population structure on neutral genetic variation and barriers to gene exchange. 2024. doi:10.15479/at:ista:18515 apa: Surendranadh, P. (2024). Effect of population structure on neutral genetic variation and barriers to gene exchange. Institute of Science and Technology Austria. https://doi.org/10.15479/at:ista:18515 chicago: Surendranadh, Parvathy. “Effect of Population Structure on Neutral Genetic Variation and Barriers to Gene Exchange.” Institute of Science and Technology Austria, 2024. https://doi.org/10.15479/at:ista:18515. ieee: P. Surendranadh, “Effect of population structure on neutral genetic variation and barriers to gene exchange,” Institute of Science and Technology Austria, 2024. ista: Surendranadh P. 2024. Effect of population structure on neutral genetic variation and barriers to gene exchange. Institute of Science and Technology Austria. mla: Surendranadh, Parvathy. Effect of Population Structure on Neutral Genetic Variation and Barriers to Gene Exchange. Institute of Science and Technology Austria, 2024, doi:10.15479/at:ista:18515. short: P. Surendranadh, Effect of Population Structure on Neutral Genetic Variation and Barriers to Gene Exchange, Institute of Science and Technology Austria, 2024. corr_author: '1' date_created: 2024-11-06T21:25:37Z date_published: 2024-11-07T00:00:00Z date_updated: 2026-04-07T12:56:52Z day: '07' ddc: - '576' degree_awarded: PhD department: - _id: GradSch - _id: NiBa doi: 10.15479/at:ista:18515 file: - access_level: open_access checksum: c32cf7bc75748d9c551d8eb70178bbec content_type: application/pdf creator: psurendr date_created: 2024-11-07T10:59:29Z date_updated: 2024-11-07T10:59:29Z file_id: '18519' file_name: PhD_Thesis__Parvathy_071124_PDFA.pdf file_size: 37019760 relation: main_file success: 1 - access_level: closed checksum: 4417e02d54084d89e75734e18caaa96d content_type: application/zip creator: psurendr date_created: 2024-11-07T10:59:42Z date_updated: 2024-11-07T10:59:42Z file_id: '18520' file_name: PhD Thesis- Parvathy_071124.zip file_size: 41198857 relation: source_file file_date_updated: 2024-11-07T10:59:42Z has_accepted_license: '1' language: - iso: eng license: https://creativecommons.org/licenses/by-nc-sa/4.0/ month: '11' oa: 1 oa_version: Published Version page: '219' project: - _id: 05959E1C-7A3F-11EA-A408-12923DDC885E grant_number: P32166 name: Snapdragon Speciation - _id: bd6958e0-d553-11ed-ba76-86eba6a76c00 grant_number: '101055327' name: Understanding the evolution of continuous genomes publication_identifier: issn: - 2663-337X publication_status: published publisher: Institute of Science and Technology Austria status: public supervisor: - first_name: Nicholas H full_name: Barton, Nicholas H id: 4880FE40-F248-11E8-B48F-1D18A9856A87 last_name: Barton orcid: 0000-0002-8548-5240 title: Effect of population structure on neutral genetic variation and barriers to gene exchange tmp: image: /images/cc_by_nc_sa.png legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) short: CC BY-NC-SA (4.0) type: dissertation user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd year: '2024' ... --- APC_amount: 2748 EUR OA_place: publisher OA_type: hybrid _id: '18521' abstract: - lang: eng text: In distributed systems with processes that do not share a global clock, partial synchrony is achieved by clock synchronization that guarantees bounded clock skew among all applications. Existing solutions for distributed runtime verification under partial synchrony against temporal logic specifications are exact but suffer from significant computational overhead. In this paper, we propose an approximate distributed monitoring algorithm for Signal Temporal Logic (STL) that mitigates this issue by abstracting away potential interleaving behaviors. This conservative abstraction enables a significant speedup of the distributed monitors, albeit with a tradeoff in accuracy. We address this tradeoff with a methodology that combines our approximate monitor with its exact counterpart, resulting in enhanced efficiency without sacrificing precision. We evaluate our approach with multiple experiments, showcasing its efficacy in both real-world applications and synthetic examples. acknowledgement: This work was supported in part by the ERC-2020-AdG 101020093. This work is sponsored in part by the United States NSF CCF-2118356 award. This research was partially funded by A-IQ Ready (Chips JU, grant agreement No. 101096658). alternative_title: - LNCS article_processing_charge: Yes (in subscription journal) arxiv: 1 author: - first_name: Borzoo full_name: Bonakdarpour, Borzoo last_name: Bonakdarpour - first_name: Anik full_name: Momtaz, Anik last_name: Momtaz - first_name: Dejan full_name: Nickovic, Dejan id: 41BCEE5C-F248-11E8-B48F-1D18A9856A87 last_name: Nickovic - first_name: Naci E full_name: Sarac, Naci E id: 8C6B42F8-C8E6-11E9-A03A-F2DCE5697425 last_name: Sarac citation: ama: 'Bonakdarpour B, Momtaz A, Nickovic D, Sarac NE. Approximate distributed monitoring under partial synchrony: Balancing speed & accuracy. In: 24th International Conference on Runtime Verification. Vol 15191. Springer Nature; 2024:282-301. doi:10.1007/978-3-031-74234-7_18' apa: 'Bonakdarpour, B., Momtaz, A., Nickovic, D., & Sarac, N. E. (2024). Approximate distributed monitoring under partial synchrony: Balancing speed & accuracy. In 24th International Conference on Runtime Verification (Vol. 15191, pp. 282–301). Istanbul, Turkey: Springer Nature. https://doi.org/10.1007/978-3-031-74234-7_18' chicago: 'Bonakdarpour, Borzoo, Anik Momtaz, Dejan Nickovic, and Naci E Sarac. “Approximate Distributed Monitoring under Partial Synchrony: Balancing Speed & Accuracy.” In 24th International Conference on Runtime Verification, 15191:282–301. Springer Nature, 2024. https://doi.org/10.1007/978-3-031-74234-7_18.' ieee: 'B. Bonakdarpour, A. Momtaz, D. Nickovic, and N. E. Sarac, “Approximate distributed monitoring under partial synchrony: Balancing speed & accuracy,” in 24th International Conference on Runtime Verification, Istanbul, Turkey, 2024, vol. 15191, pp. 282–301.' ista: 'Bonakdarpour B, Momtaz A, Nickovic D, Sarac NE. 2024. Approximate distributed monitoring under partial synchrony: Balancing speed & accuracy. 24th International Conference on Runtime Verification. RV: Conference on Runtime Verification, LNCS, vol. 15191, 282–301.' mla: 'Bonakdarpour, Borzoo, et al. “Approximate Distributed Monitoring under Partial Synchrony: Balancing Speed & Accuracy.” 24th International Conference on Runtime Verification, vol. 15191, Springer Nature, 2024, pp. 282–301, doi:10.1007/978-3-031-74234-7_18.' short: B. Bonakdarpour, A. Momtaz, D. Nickovic, N.E. Sarac, in:, 24th International Conference on Runtime Verification, Springer Nature, 2024, pp. 282–301. conference: end_date: 2024-10-17 location: Istanbul, Turkey name: 'RV: Conference on Runtime Verification' start_date: 2024-10-15 corr_author: '1' date_created: 2024-11-10T23:01:58Z date_published: 2024-10-12T00:00:00Z date_updated: 2026-05-20T08:43:20Z day: '12' ddc: - '000' department: - _id: ToHe - _id: GradSch doi: 10.1007/978-3-031-74234-7_18 ec_funded: 1 external_id: arxiv: - '2408.05033' isi: - '001420093700018' file: - access_level: open_access checksum: 7b8ca21b8c19ab796fa445b0e54003ca content_type: application/pdf creator: dernst date_created: 2024-11-11T09:42:28Z date_updated: 2024-11-11T09:42:28Z file_id: '18539' file_name: 2024_LNCS_Bonakdarpour.pdf file_size: 1897101 relation: main_file success: 1 file_date_updated: 2024-11-11T09:42:28Z has_accepted_license: '1' intvolume: ' 15191' isi: 1 language: - iso: eng month: '10' oa: 1 oa_version: Published Version page: 282-301 project: - _id: 62781420-2b32-11ec-9570-8d9b63373d4d call_identifier: H2020 grant_number: '101020093' name: Vigilant Algorithmic Monitoring of Software publication: 24th International Conference on Runtime Verification publication_identifier: eissn: - 1611-3349 isbn: - '9783031742330' issn: - 0302-9743 publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: 'Approximate distributed monitoring under partial synchrony: Balancing speed & accuracy' tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: conference user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 15191 year: '2024' ... --- DOAJ_listed: '1' OA_place: publisher OA_type: gold _id: '18523' abstract: - lang: eng text: "Recent observations from the EIGER JWST program have measured for the first time the quasar–galaxy cross-correlation function at z ≈ 6. The autocorrelation function of faint z ≈ 6 quasars was also recently estimated. These measurements provide key insights into the properties of quasars and galaxies at high redshift and their relation with the host dark matter haloes. In this work, we interpret these data building upon an empirical quasar population model that has been applied successfully to quasar clustering and demographic measurements at z ≈ 2–4. We use a new, large-volume N-body simulation with more than a trillion particles, FLAMINGO-10k, to model quasars and galaxies simultaneously. We successfully reproduce observations of z ≈ 6 quasars and galaxies (i.e. their clustering properties and luminosity functions), and infer key quantities such as their luminosity–halo mass relation, the mass function of their host haloes, and their duty cycle/occupation fraction. Our key findings\r\nare (i) quasars reside on average in ≈ 1012.5 M haloes (corresponding to ≈ 5σ fluctuations in the initial conditions of the linear density field), but the distribution of host halo masses is quite broad; (ii) the duty cycle of (UV-bright) quasar activity is relatively low (≈ 1 per cent); (iii) galaxies (that are bright in [O III]) live in much smaller haloes (≈ 1010.9 M) and have a larger duty cycle (occupation fraction) of ≈ 13 per cent. Finally, we focus on the inferred properties of quasars and present a homogeneous analysis of their evolution with redshift. The picture that emerges reveals a strong evolution of the host halo mass and duty cycle of quasars at z ≈ 2–6, and calls for new investigations of the role of quasar activity across cosmic time." acknowledgement: "We are grateful to Junya Arita and the SHELLQs team for sharing their data on the quasar autocorrelation function and to Jan-Torge Schindler for discussion on the QLF. We acknowledge helpful conversations with the ENIGMA group at UC Santa Barbara and Leiden University. EP is grateful to Rob McGibbon and Victor Forouhar Moreno for help with the simulation outputs, and to Timo Kist, Jiamu Huang, and Vikram Khaire for comments on an early version of the manuscript. JFH and EP acknowledge support from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (grant agreement No 885301). This work is partly supported by funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 860744 (BiD4BESt). FW acknowledges support from NSF grant AST-2308258. This work used the DiRAC Memory Intensive service (Cosma8) at the University of Durham, which is part of the STFC DiRAC HPC Facility (www.dirac.ac.uk). Access to DiRAC resources was granted through a Director’s Discretionary Time allocation in 2023/24, under the auspices of the UKRI-funded\r\nDiRAC Federation Project. The equipment was funded by BEIS capital funding via STFC capital grants ST/K00042X/1, ST/P002293/1, ST/R002371/1, and ST/S002502/1, Durham University, and STFC operations grant ST/R000832/1. DiRAC is part of the National e-Infrastructure." article_processing_charge: Yes article_type: original author: - first_name: Elia full_name: Pizzati, Elia last_name: Pizzati - first_name: Joseph F. full_name: Hennawi, Joseph F. last_name: Hennawi - first_name: Joop full_name: Schaye, Joop last_name: Schaye - first_name: Matthieu full_name: Schaller, Matthieu last_name: Schaller - first_name: Anna Christina full_name: Eilers, Anna Christina last_name: Eilers - first_name: Feige full_name: Wang, Feige last_name: Wang - first_name: Carlos S. full_name: Frenk, Carlos S. last_name: Frenk - first_name: Willem full_name: Elbers, Willem last_name: Elbers - first_name: John C. full_name: Helly, John C. last_name: Helly - first_name: Ruari full_name: Mackenzie, Ruari last_name: Mackenzie - first_name: Jorryt J full_name: Matthee, Jorryt J id: 7439a258-f3c0-11ec-9501-9df22fe06720 last_name: Matthee orcid: 0000-0003-2871-127X - first_name: Rongmon full_name: Bordoloi, Rongmon last_name: Bordoloi - first_name: Daichi full_name: Kashino, Daichi last_name: Kashino - first_name: Rohan P. full_name: Naidu, Rohan P. last_name: Naidu - first_name: Minghao full_name: Yue, Minghao last_name: Yue citation: ama: Pizzati E, Hennawi JF, Schaye J, et al. A unified model for the clustering of quasars and galaxies at z ≈ 6. Monthly Notices of the Royal Astronomical Society. 2024;534(4):3155-3175. doi:10.1093/mnras/stae2307 apa: Pizzati, E., Hennawi, J. F., Schaye, J., Schaller, M., Eilers, A. C., Wang, F., … Yue, M. (2024). A unified model for the clustering of quasars and galaxies at z ≈ 6. Monthly Notices of the Royal Astronomical Society. Oxford University Press. https://doi.org/10.1093/mnras/stae2307 chicago: Pizzati, Elia, Joseph F. Hennawi, Joop Schaye, Matthieu Schaller, Anna Christina Eilers, Feige Wang, Carlos S. Frenk, et al. “A Unified Model for the Clustering of Quasars and Galaxies at z ≈ 6.” Monthly Notices of the Royal Astronomical Society. Oxford University Press, 2024. https://doi.org/10.1093/mnras/stae2307. ieee: E. Pizzati et al., “A unified model for the clustering of quasars and galaxies at z ≈ 6,” Monthly Notices of the Royal Astronomical Society, vol. 534, no. 4. Oxford University Press, pp. 3155–3175, 2024. ista: Pizzati E, Hennawi JF, Schaye J, Schaller M, Eilers AC, Wang F, Frenk CS, Elbers W, Helly JC, Mackenzie R, Matthee JJ, Bordoloi R, Kashino D, Naidu RP, Yue M. 2024. A unified model for the clustering of quasars and galaxies at z ≈ 6. Monthly Notices of the Royal Astronomical Society. 534(4), 3155–3175. mla: Pizzati, Elia, et al. “A Unified Model for the Clustering of Quasars and Galaxies at z ≈ 6.” Monthly Notices of the Royal Astronomical Society, vol. 534, no. 4, Oxford University Press, 2024, pp. 3155–75, doi:10.1093/mnras/stae2307. short: E. Pizzati, J.F. Hennawi, J. Schaye, M. Schaller, A.C. Eilers, F. Wang, C.S. Frenk, W. Elbers, J.C. Helly, R. Mackenzie, J.J. Matthee, R. Bordoloi, D. Kashino, R.P. Naidu, M. Yue, Monthly Notices of the Royal Astronomical Society 534 (2024) 3155–3175. date_created: 2024-11-10T23:01:58Z date_published: 2024-11-01T00:00:00Z date_updated: 2025-09-08T14:40:22Z day: '01' ddc: - '520' department: - _id: JoMa doi: 10.1093/mnras/stae2307 external_id: isi: - '001335663900008' file: - access_level: open_access checksum: 9ea6285dd1d04d7a9e7b40a4c9e11edb content_type: application/pdf creator: dernst date_created: 2024-11-12T07:17:26Z date_updated: 2024-11-12T07:17:26Z file_id: '18542' file_name: 2024_MonthlyNRoyalAstronSoc_Pizzati.pdf file_size: 2954312 relation: main_file success: 1 file_date_updated: 2024-11-12T07:17:26Z has_accepted_license: '1' intvolume: ' 534' isi: 1 issue: '4' language: - iso: eng month: '11' oa: 1 oa_version: Published Version page: 3155-3175 publication: Monthly Notices of the Royal Astronomical Society publication_identifier: eissn: - 1365-2966 issn: - 0035-8711 publication_status: published publisher: Oxford University Press quality_controlled: '1' scopus_import: '1' status: public title: A unified model for the clustering of quasars and galaxies at z ≈ 6 tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 534 year: '2024' ... --- DOAJ_listed: '1' OA_place: publisher OA_type: gold _id: '18524' abstract: - lang: eng text: Recent works have constrained the binary fraction of evolved populations of massive stars in local galaxies such as red supergiants and Wolf–Rayet stars, but the binary fraction of yellow supergiants (YSGs) in the Hertzsprung gap remains unconstrained. Binary evolution theory predicts that the Hertzsprung gap is home to multiple populations of binary systems with varied evolutionary histories. In this paper, we develop a method to distinguish single YSGs from YSG plus O- or B-type main-sequence binaries using optical and ultraviolet photometry, and then apply this method to identify candidate YSG binaries in the Magellanic Clouds. After constructing a set of combined stellar atmosphere models, we find that optical photometry is, given typical measurement and reddening uncertainties, sufficient to discern single YSGs from YSG+OB binaries if the OB-star is at least ∼5M⊙ for Teff,YSG ∼ 4000 K, but requires a ∼20M⊙ OB star for YSGs up to Teff,YSG ∼ 9000 K. For these hotter YSG temperatures, ultraviolet photometry allows binaries with OB companions as small as ∼7M⊙ to be identified. We use color–color spaces developed from these models to search for evidence of excess blue or ultraviolet light in a set of ∼1000 YSG candidates in the Magellanic Clouds. We identify hundreds of candidate YSG binary systems and report a preliminary fraction of YSGs that show a blue/UV color excess of 20%–60%. Spectroscopic follow-up is now required to confirm the true nature of this population. acknowledgement: "The authors thank Aaron Tohuvavohu, Katie Breivik, Marten van Kerkwijk, Jakub Klencki, Eva Laplace, and Dae-Sik Moon for helpful discussions, and Adiv Paradise for helpful edits. The authors also thank the anonymous reviewer for a helpful and constructive referee report.\r\nThe authors at the University of Toronto acknowledge that the land on which the University of Toronto operates is the traditional territory of the Huron–Wendat, the Seneca, and the Mississaugas of the Credit River. They are grateful to have the opportunity to work on this land.\r\nThe Dunlap Institute is funded through an endowment established by the David Dunlap family and the University of Toronto.\r\nA.J.G.O. is supported by a McWilliams Fellowship at Carnegie Mellon University. M.R.D. acknowledges support from the NSERC through grant RGPIN-2019-06186, the Canada Research Chairs Program, and the Dunlap Institute at the University of Toronto. B.M.G. acknowledges the support of the Natural Sciences and Engineering Research Council of Canada (NSERC) through grant RGPIN-2022-03163, and of the Canada Research Chairs program. Support for this work was provided by NASA through the NASA Hubble Fellowship Program grant Nos. HST-HF2-51457.001-A and HST-HF2-51516 awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., for NASA, under contract NAS5-26555.\r\nThis research has made use of the SIMBAD database (M. Wenger et al. 2000), operated at CDS, Strasbourg, France, and the SVO Filter Profile Service 13 supported by the Spanish MINECO through grant AYA2017-84089 (C. Rodrigo et al. 2012, 2020).\r\nThis research has made use of the following software: astropy (Astropy Collaboration et al. 2013, 2018, 2022), IRAF (D. Tody 1986, 1993), and TOPCAT (M. B. Taylor 2005)." article_number: '29' article_processing_charge: No article_type: original arxiv: 1 author: - first_name: Anna J.G. full_name: O’Grady, Anna J.G. last_name: O’Grady - first_name: Maria R. full_name: Drout, Maria R. last_name: Drout - first_name: Kathryn F. full_name: Neugent, Kathryn F. last_name: Neugent - first_name: Bethany full_name: Ludwig, Bethany last_name: Ludwig - first_name: Ylva Louise Linsdotter full_name: Götberg, Ylva Louise Linsdotter id: d0648d0c-0f64-11ee-a2e0-dd0faa2e4f7d last_name: Götberg orcid: 0000-0002-6960-6911 - first_name: B. M. full_name: Gaensler, B. M. last_name: Gaensler citation: ama: O’Grady AJG, Drout MR, Neugent KF, Ludwig B, Götberg YLL, Gaensler BM. Binary yellow supergiants in the Magellanic Clouds. I. Photometric candidate identification. Astrophysical Journal. 2024;975. doi:10.3847/1538-4357/ad778a apa: O’Grady, A. J. G., Drout, M. R., Neugent, K. F., Ludwig, B., Götberg, Y. L. L., & Gaensler, B. M. (2024). Binary yellow supergiants in the Magellanic Clouds. I. Photometric candidate identification. Astrophysical Journal. IOP Publishing. https://doi.org/10.3847/1538-4357/ad778a chicago: O’Grady, Anna J.G., Maria R. Drout, Kathryn F. Neugent, Bethany Ludwig, Ylva Louise Linsdotter Götberg, and B. M. Gaensler. “Binary Yellow Supergiants in the Magellanic Clouds. I. Photometric Candidate Identification.” Astrophysical Journal. IOP Publishing, 2024. https://doi.org/10.3847/1538-4357/ad778a. ieee: A. J. G. O’Grady, M. R. Drout, K. F. Neugent, B. Ludwig, Y. L. L. Götberg, and B. M. Gaensler, “Binary yellow supergiants in the Magellanic Clouds. I. Photometric candidate identification,” Astrophysical Journal, vol. 975. IOP Publishing, 2024. ista: O’Grady AJG, Drout MR, Neugent KF, Ludwig B, Götberg YLL, Gaensler BM. 2024. Binary yellow supergiants in the Magellanic Clouds. I. Photometric candidate identification. Astrophysical Journal. 975, 29. mla: O’Grady, Anna J. G., et al. “Binary Yellow Supergiants in the Magellanic Clouds. I. Photometric Candidate Identification.” Astrophysical Journal, vol. 975, 29, IOP Publishing, 2024, doi:10.3847/1538-4357/ad778a. short: A.J.G. O’Grady, M.R. Drout, K.F. Neugent, B. Ludwig, Y.L.L. Götberg, B.M. Gaensler, Astrophysical Journal 975 (2024). date_created: 2024-11-10T23:01:59Z date_published: 2024-11-01T00:00:00Z date_updated: 2025-09-08T14:37:18Z day: '01' ddc: - '520' department: - _id: YlGo doi: 10.3847/1538-4357/ad778a external_id: arxiv: - '2406.17177' isi: - '001339486900001' file: - access_level: open_access checksum: 0e9bb88b5048ecc782ac27953c84b8ce content_type: application/pdf creator: dernst date_created: 2024-11-11T09:20:45Z date_updated: 2024-11-11T09:20:45Z file_id: '18535' file_name: 2024_AstrophysicalJour_Grady.pdf file_size: 34634395 relation: main_file success: 1 file_date_updated: 2024-11-11T09:20:45Z has_accepted_license: '1' intvolume: ' 975' isi: 1 language: - iso: eng month: '11' oa: 1 oa_version: Published Version publication: Astrophysical Journal publication_identifier: eissn: - 1538-4357 issn: - 0004-637X publication_status: published publisher: IOP Publishing quality_controlled: '1' scopus_import: '1' status: public title: Binary yellow supergiants in the Magellanic Clouds. I. Photometric candidate identification tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 975 year: '2024' ... --- APC_amount: 3062,93 EUR OA_place: publisher OA_type: hybrid _id: '18525' abstract: - lang: eng text: As their statistical power grows, genome-wide association studies (GWAS) have identified an increasing number of loci underlying quantitative traits of interest. These loci are scattered throughout the genome and are individually responsible only for small fractions of the total heritable trait variance. The recently proposed omnigenic model provides a conceptual framework to explain these observations by postulating that numerous distant loci contribute to each complex trait via effect propagation through intracellular regulatory networks. We formalize this conceptual framework by proposing the “quantitative omnigenic model” (QOM), a statistical model that combines prior knowledge of the regulatory network topology with genomic data. By applying our model to gene expression traits in yeast, we demonstrate that QOM achieves similar gene expression prediction performance to traditional GWAS with hundreds of times less parameters, while simultaneously extracting candidate causal and quantitative chains of effect propagation through the regulatory network for every individual gene. We estimate the fraction of heritable trait variance in cis- and in trans-, break the latter down by effect propagation order, assess the trans- variance not attributable to transcriptional regulation, and show that QOM correctly accounts for the low-dimensional structure of gene expression covariance. We furthermore demonstrate the relevance of QOM for systems biology, by employing it as a statistical test for the quality of regulatory network reconstructions, and linking it to the propagation of nontranscriptional (including environmental) effects. acknowledgement: N.R.acknowledges the support of the Austrian Academy of Sciences through the Doctoral Fellowship Programme (DOC) of the Austrian Academy of Sciences 26917. M.H. and G.T. were supported in part by the Human Frontiers Science Program Grant RGP0034/2018. We thank Nicholas H. Barton, Fyodor Kondrashov, and Matthew R. Robinson for fruitful discussions. article_number: e2402340121 article_processing_charge: Yes article_type: original author: - first_name: Natalia full_name: Ruzickova, Natalia id: D2761128-D73D-11E9-A1BF-BA0DE6697425 last_name: Ruzickova - first_name: Michal full_name: Hledik, Michal id: 4171253A-F248-11E8-B48F-1D18A9856A87 last_name: Hledik - first_name: Gašper full_name: Tkačik, Gašper id: 3D494DCA-F248-11E8-B48F-1D18A9856A87 last_name: Tkačik orcid: 0000-0002-6699-1455 citation: ama: Ruzickova N, Hledik M, Tkačik G. Quantitative omnigenic model discovers interpretable genome-wide associations. Proceedings of the National Academy of Sciences of the United States of America. 2024;121(44). doi:10.1073/pnas.2402340121 apa: Ruzickova, N., Hledik, M., & Tkačik, G. (2024). Quantitative omnigenic model discovers interpretable genome-wide associations. Proceedings of the National Academy of Sciences of the United States of America. National Academy of Sciences. https://doi.org/10.1073/pnas.2402340121 chicago: Ruzickova, Natalia, Michal Hledik, and Gašper Tkačik. “Quantitative Omnigenic Model Discovers Interpretable Genome-Wide Associations.” Proceedings of the National Academy of Sciences of the United States of America. National Academy of Sciences, 2024. https://doi.org/10.1073/pnas.2402340121. ieee: N. Ruzickova, M. Hledik, and G. Tkačik, “Quantitative omnigenic model discovers interpretable genome-wide associations,” Proceedings of the National Academy of Sciences of the United States of America, vol. 121, no. 44. National Academy of Sciences, 2024. ista: Ruzickova N, Hledik M, Tkačik G. 2024. Quantitative omnigenic model discovers interpretable genome-wide associations. Proceedings of the National Academy of Sciences of the United States of America. 121(44), e2402340121. mla: Ruzickova, Natalia, et al. “Quantitative Omnigenic Model Discovers Interpretable Genome-Wide Associations.” Proceedings of the National Academy of Sciences of the United States of America, vol. 121, no. 44, e2402340121, National Academy of Sciences, 2024, doi:10.1073/pnas.2402340121. short: N. Ruzickova, M. Hledik, G. Tkačik, Proceedings of the National Academy of Sciences of the United States of America 121 (2024). corr_author: '1' date_created: 2024-11-10T23:01:59Z date_published: 2024-10-29T00:00:00Z date_updated: 2026-04-07T12:02:39Z day: '29' ddc: - '570' department: - _id: GaTk - _id: NiBa doi: 10.1073/pnas.2402340121 external_id: isi: - '001349462600001' pmid: - '39441639' file: - access_level: open_access checksum: d930e2ccf9ec900c7d7509a78cfb3564 content_type: application/pdf creator: dernst date_created: 2024-11-11T09:31:00Z date_updated: 2024-11-11T09:31:00Z file_id: '18536' file_name: 2024_PNAS_Ruzickova.pdf file_size: 25529709 relation: main_file success: 1 file_date_updated: 2024-11-11T09:31:00Z has_accepted_license: '1' intvolume: ' 121' isi: 1 issue: '44' language: - iso: eng month: '10' oa: 1 oa_version: Published Version pmid: 1 project: - _id: 7bec9174-9f16-11ee-852c-ded9fe5f810e name: Collective behaviour of cells in pancreatic Islets of Langerhans - _id: 2665AAFE-B435-11E9-9278-68D0E5697425 grant_number: RGP0034/2018 name: Can evolution minimize spurious signaling crosstalk to reach optimal performance? publication: Proceedings of the National Academy of Sciences of the United States of America publication_identifier: eissn: - 1091-6490 issn: - 0027-8424 publication_status: published publisher: National Academy of Sciences quality_controlled: '1' related_material: record: - id: '20357' relation: dissertation_contains status: public scopus_import: '1' status: public title: Quantitative omnigenic model discovers interpretable genome-wide associations tmp: image: /images/cc_by_nc_nd.png legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) short: CC BY-NC-ND (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 121 year: '2024' ... --- OA_place: publisher OA_type: hybrid _id: '18526' abstract: - lang: eng text: Multivesicular endosomes (MVEs) sequester membrane proteins destined for degradation within intralumenal vesicles (ILVs), a process mediated by the membrane-remodeling action of Endosomal Sorting Complex Required for Transport (ESCRT) proteins. In Arabidopsis, endosomal membrane constriction and scission are uncoupled, resulting in the formation of extensive concatenated ILV networks and enhancing cargo sequestration efficiency. Here, we used a combination of electron tomography, computer simulations, and mathematical modeling to address the questions of when concatenated ILV networks evolved in plants and what drives their formation. Through morphometric analyses of tomographic reconstructions of endosomes across yeast, algae, and various land plants, we have found that ILV concatenation is widespread within plant species, but only prevalent in seed plants, especially in flowering plants. Multiple budding sites that require the formation of pores in the limiting membrane were only identified in hornworts and seed plants, suggesting that this mechanism has evolved independently in both plant lineages. To identify the conditions under which these multiple budding sites can arise, we used particle-based molecular dynamics simulations and found that changes in ESCRT filament properties, such as filament curvature and membrane binding energy, can generate the membrane shapes observed in multiple budding sites. To understand the relationship between membrane budding activity and ILV network topology, we performed computational simulations and identified a set of membrane remodeling parameters that can recapitulate our tomographic datasets. acknowledgement: We would like to thank Janice Pennington for her support with electron tomography data collection, Dr. Ingrid Jordon-Thaden, director of the Botany Garden and Greenhouse of University of Wisconsin Madison, for her invaluable assistance collecting plant materials, Dr. Marie Trest for providing Chara specimens, and Dr. Nicholas Keuler for his advice on statistical analyses. We thank Charlie Hamilton for exploring the initial computational model. This work was supported by grant NSF MCB 2114603 and NIH 1S10OD026769-01 to M.S.O. F.F acknowledges support as a NOMIS Fellow from the NOMIS Foundation. A.Š. acknowledges ERC Starting Grant “NEPA” 802960. article_number: e2409407121 article_processing_charge: Yes (in subscription journal) article_type: original author: - first_name: Ethan full_name: Weiner, Ethan last_name: Weiner - first_name: Elizabeth full_name: Berryman, Elizabeth last_name: Berryman - first_name: Felix F full_name: Frey, Felix F id: a0270b37-8f1a-11ec-95c7-8e710c59a4f3 last_name: Frey orcid: 0000-0001-8501-6017 - first_name: Ariadna González full_name: Solís, Ariadna González last_name: Solís - first_name: André full_name: Leier, André last_name: Leier - first_name: Tatiana Marquez full_name: Lago, Tatiana Marquez last_name: Lago - first_name: Anđela full_name: Šarić, Anđela id: bf63d406-f056-11eb-b41d-f263a6566d8b last_name: Šarić orcid: 0000-0002-7854-2139 - first_name: Marisa S. full_name: Otegui, Marisa S. last_name: Otegui citation: ama: Weiner E, Berryman E, Frey FF, et al. Endosomal membrane budding patterns in plants. Proceedings of the National Academy of Sciences of the United States of America. 2024;121(44). doi:10.1073/pnas.2409407121 apa: Weiner, E., Berryman, E., Frey, F. F., Solís, A. G., Leier, A., Lago, T. M., … Otegui, M. S. (2024). Endosomal membrane budding patterns in plants. Proceedings of the National Academy of Sciences of the United States of America. National Academy of Sciences. https://doi.org/10.1073/pnas.2409407121 chicago: Weiner, Ethan, Elizabeth Berryman, Felix F Frey, Ariadna González Solís, André Leier, Tatiana Marquez Lago, Anđela Šarić, and Marisa S. Otegui. “Endosomal Membrane Budding Patterns in Plants.” Proceedings of the National Academy of Sciences of the United States of America. National Academy of Sciences, 2024. https://doi.org/10.1073/pnas.2409407121. ieee: E. Weiner et al., “Endosomal membrane budding patterns in plants,” Proceedings of the National Academy of Sciences of the United States of America, vol. 121, no. 44. National Academy of Sciences, 2024. ista: Weiner E, Berryman E, Frey FF, Solís AG, Leier A, Lago TM, Šarić A, Otegui MS. 2024. Endosomal membrane budding patterns in plants. Proceedings of the National Academy of Sciences of the United States of America. 121(44), e2409407121. mla: Weiner, Ethan, et al. “Endosomal Membrane Budding Patterns in Plants.” Proceedings of the National Academy of Sciences of the United States of America, vol. 121, no. 44, e2409407121, National Academy of Sciences, 2024, doi:10.1073/pnas.2409407121. short: E. Weiner, E. Berryman, F.F. Frey, A.G. Solís, A. Leier, T.M. Lago, A. Šarić, M.S. Otegui, Proceedings of the National Academy of Sciences of the United States of America 121 (2024). date_created: 2024-11-10T23:01:59Z date_published: 2024-10-29T00:00:00Z date_updated: 2025-09-08T14:38:35Z day: '29' ddc: - '570' department: - _id: AnSa doi: 10.1073/pnas.2409407121 ec_funded: 1 external_id: isi: - '001349500800007' pmid: - '39441629' file: - access_level: open_access checksum: 21c82d2ab58ff99b2bd0489797be42e5 content_type: application/pdf creator: dernst date_created: 2024-11-11T09:35:15Z date_updated: 2024-11-11T09:35:15Z file_id: '18538' file_name: 2024_PNAS_Weiner.pdf file_size: 5268074 relation: main_file success: 1 file_date_updated: 2024-11-11T09:35:15Z has_accepted_license: '1' intvolume: ' 121' isi: 1 issue: '44' language: - iso: eng month: '10' oa: 1 oa_version: Published Version pmid: 1 project: - _id: eba2549b-77a9-11ec-83b8-a81e493eae4e call_identifier: H2020 grant_number: '802960' name: 'Non-Equilibrium Protein Assembly: from Building Blocks to Biological Machines' publication: Proceedings of the National Academy of Sciences of the United States of America publication_identifier: eissn: - 1091-6490 issn: - 0027-8424 publication_status: published publisher: National Academy of Sciences quality_controlled: '1' scopus_import: '1' status: public title: Endosomal membrane budding patterns in plants tmp: image: /images/cc_by_nc_nd.png legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) short: CC BY-NC-ND (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 121 year: '2024' ... --- OA_place: publisher OA_type: hybrid _id: '18553' abstract: - lang: eng text: Transcription-coupled nucleotide excision repair (TC-NER) efficiently eliminates DNA damage that impedes gene transcription by RNA polymerase II (RNA Pol II). TC-NER is initiated by the recognition of lesion-stalled RNA Pol II by CSB, which recruits the CRL4CSA ubiquitin ligase and UVSSA. RNA Pol II ubiquitylation at RPB1-K1268 by CRL4CSA serves as a critical TC-NER checkpoint, governing RNA Pol II stability and initiating DNA damage excision by TFIIH recruitment. However, the precise regulatory mechanisms of CRL4CSA activity and TFIIH recruitment remain elusive. Here, we reveal human serine/threonine-protein kinase 19 (STK19) as a TC-NER factor, which is essential for correct DNA damage removal and subsequent transcription restart. Cryogenic electron microscopy (cryo-EM) studies demonstrate that STK19 is an integral part of the RNA Pol II-TC-NER complex, bridging CSA, UVSSA, RNA Pol II, and downstream DNA. STK19 stimulates TC-NER complex stability and CRL4CSA activity, resulting in efficient RNA Pol II ubiquitylation and correct UVSSA and TFIIH binding. These findings underscore the crucial role of STK19 as a core TC-NER component. acknowledged_ssus: - _id: LifeSc - _id: PreCl acknowledgement: We thank N. Thompson and R. Burgess for the 8WG16 hybridoma cell line. This research was further supported by the Scientific Service Units (SSU) of IST Austria through resources provided by the Lab Support Facility (LSF) and the Preclinical Facility (PCF). This work is part of the Oncode Institute, which is partly financed by the Dutch Cancer Society. Research at the Netherlands Cancer Institute is supported by institutional grants of the Dutch Cancer Society and the Dutch Ministry of Health, Welfare and Sport. This study was supported by a VICI (VI.C.182.025) and a TOP Grant (714.017.003) of the Netherlands Organization for Scientific Research. article_processing_charge: No article_type: original author: - first_name: Anisha R. full_name: Ramadhin, Anisha R. last_name: Ramadhin - first_name: Shun-Hsiao full_name: Lee, Shun-Hsiao last_name: Lee - first_name: Di full_name: Zhou, Di last_name: Zhou - first_name: Anita P full_name: Testa Salmazo, Anita P id: 41F1F098-F248-11E8-B48F-1D18A9856A87 last_name: Testa Salmazo - first_name: Camila full_name: Gonzalo-Hansen, Camila last_name: Gonzalo-Hansen - first_name: Marjolein full_name: van Sluis, Marjolein last_name: van Sluis - first_name: Cindy M.A. full_name: Blom, Cindy M.A. last_name: Blom - first_name: Roel C. full_name: Janssens, Roel C. last_name: Janssens - first_name: Anja full_name: Raams, Anja last_name: Raams - first_name: Dick full_name: Dekkers, Dick last_name: Dekkers - first_name: Karel full_name: Bezstarosti, Karel last_name: Bezstarosti - first_name: Dea full_name: Slade, Dea last_name: Slade - first_name: Wim full_name: Vermeulen, Wim last_name: Vermeulen - first_name: Alex full_name: Pines, Alex last_name: Pines - first_name: Jeroen A.A. full_name: Demmers, Jeroen A.A. last_name: Demmers - first_name: Carrie A full_name: Bernecky, Carrie A id: 2CB9DFE2-F248-11E8-B48F-1D18A9856A87 last_name: Bernecky orcid: 0000-0003-0893-7036 - first_name: Titia K. full_name: Sixma, Titia K. last_name: Sixma - first_name: Jurgen A. full_name: Marteijn, Jurgen A. last_name: Marteijn citation: ama: Ramadhin AR, Lee S-H, Zhou D, et al. STK19 drives transcription-coupled repair by stimulating repair complex stability, RNA Pol II ubiquitylation, and TFIIH recruitment. Molecular Cell. 2024;84(24):4740-4757.e12. doi:10.1016/j.molcel.2024.10.030 apa: Ramadhin, A. R., Lee, S.-H., Zhou, D., Testa Salmazo, A. P., Gonzalo-Hansen, C., van Sluis, M., … Marteijn, J. A. (2024). STK19 drives transcription-coupled repair by stimulating repair complex stability, RNA Pol II ubiquitylation, and TFIIH recruitment. Molecular Cell. Elsevier. https://doi.org/10.1016/j.molcel.2024.10.030 chicago: Ramadhin, Anisha R., Shun-Hsiao Lee, Di Zhou, Anita P Testa Salmazo, Camila Gonzalo-Hansen, Marjolein van Sluis, Cindy M.A. Blom, et al. “STK19 Drives Transcription-Coupled Repair by Stimulating Repair Complex Stability, RNA Pol II Ubiquitylation, and TFIIH Recruitment.” Molecular Cell. Elsevier, 2024. https://doi.org/10.1016/j.molcel.2024.10.030. ieee: A. R. Ramadhin et al., “STK19 drives transcription-coupled repair by stimulating repair complex stability, RNA Pol II ubiquitylation, and TFIIH recruitment,” Molecular Cell, vol. 84, no. 24. Elsevier, p. 4740–4757.e12, 2024. ista: Ramadhin AR, Lee S-H, Zhou D, Testa Salmazo AP, Gonzalo-Hansen C, van Sluis M, Blom CMA, Janssens RC, Raams A, Dekkers D, Bezstarosti K, Slade D, Vermeulen W, Pines A, Demmers JAA, Bernecky C, Sixma TK, Marteijn JA. 2024. STK19 drives transcription-coupled repair by stimulating repair complex stability, RNA Pol II ubiquitylation, and TFIIH recruitment. Molecular Cell. 84(24), 4740–4757.e12. mla: Ramadhin, Anisha R., et al. “STK19 Drives Transcription-Coupled Repair by Stimulating Repair Complex Stability, RNA Pol II Ubiquitylation, and TFIIH Recruitment.” Molecular Cell, vol. 84, no. 24, Elsevier, 2024, p. 4740–4757.e12, doi:10.1016/j.molcel.2024.10.030. short: A.R. Ramadhin, S.-H. Lee, D. Zhou, A.P. Testa Salmazo, C. Gonzalo-Hansen, M. van Sluis, C.M.A. Blom, R.C. Janssens, A. Raams, D. Dekkers, K. Bezstarosti, D. Slade, W. Vermeulen, A. Pines, J.A.A. Demmers, C. Bernecky, T.K. Sixma, J.A. Marteijn, Molecular Cell 84 (2024) 4740–4757.e12. date_created: 2024-11-15T12:12:54Z date_published: 2024-12-19T00:00:00Z date_updated: 2025-09-08T14:42:50Z day: '19' ddc: - '570' department: - _id: CaBe doi: 10.1016/j.molcel.2024.10.030 external_id: isi: - '001395711300001' pmid: - '39547223' file: - access_level: open_access checksum: e051e2766b2d424983778f742cb7c5ed content_type: application/pdf creator: dernst date_created: 2025-01-13T11:17:35Z date_updated: 2025-01-13T11:17:35Z file_id: '18844' file_name: 2024_MolecularCell_Ramadhin.pdf file_size: 25071994 relation: main_file success: 1 file_date_updated: 2025-01-13T11:17:35Z has_accepted_license: '1' intvolume: ' 84' isi: 1 issue: '24' language: - iso: eng month: '12' oa: 1 oa_version: Published Version page: 4740-4757.e12 pmid: 1 publication: Molecular Cell publication_identifier: issn: - 1097-2765 publication_status: published publisher: Elsevier quality_controlled: '1' scopus_import: '1' status: public title: STK19 drives transcription-coupled repair by stimulating repair complex stability, RNA Pol II ubiquitylation, and TFIIH recruitment tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 84 year: '2024' ... --- OA_place: publisher OA_type: hybrid _id: '18554' abstract: - lang: eng text: We prove the Eigenstate Thermalization Hypothesis for general Wigner-type matrices in the bulk of the self-consistent spectrum, with optimal control on the fluctuations for obs ervables of arbitrary rank. As the main technical ingredient, we prove rank-uniform optimal local laws for one and two resolvents of a Wigner-type matrix with regular observables. Our results hold under very general conditions on the variance profile, even allowing many vanishing entries, demonstrating that Eigenstate Thermalization occurs robustly across a diverse class of random matrix ensembles, for which the underlying quantum system has a non-trivial spatial structure. acknowledgement: Open access funding provided by Institute of Science and Technology (IST Austria). article_number: '282' article_processing_charge: Yes (via OA deal) article_type: original arxiv: 1 author: - first_name: László full_name: Erdös, László id: 4DBD5372-F248-11E8-B48F-1D18A9856A87 last_name: Erdös orcid: 0000-0001-5366-9603 - first_name: Volodymyr full_name: Riabov, Volodymyr id: 1949f904-edfb-11eb-afb5-e2dfddabb93b last_name: Riabov citation: ama: Erdös L, Riabov V. Eigenstate Thermalization Hypothesis for Wigner-type matrices. Communications in Mathematical Physics. 2024;405(12). doi:10.1007/s00220-024-05143-y apa: Erdös, L., & Riabov, V. (2024). Eigenstate Thermalization Hypothesis for Wigner-type matrices. Communications in Mathematical Physics. Springer Nature. https://doi.org/10.1007/s00220-024-05143-y chicago: Erdös, László, and Volodymyr Riabov. “Eigenstate Thermalization Hypothesis for Wigner-Type Matrices.” Communications in Mathematical Physics. Springer Nature, 2024. https://doi.org/10.1007/s00220-024-05143-y. ieee: L. Erdös and V. Riabov, “Eigenstate Thermalization Hypothesis for Wigner-type matrices,” Communications in Mathematical Physics, vol. 405, no. 12. Springer Nature, 2024. ista: Erdös L, Riabov V. 2024. Eigenstate Thermalization Hypothesis for Wigner-type matrices. Communications in Mathematical Physics. 405(12), 282. mla: Erdös, László, and Volodymyr Riabov. “Eigenstate Thermalization Hypothesis for Wigner-Type Matrices.” Communications in Mathematical Physics, vol. 405, no. 12, 282, Springer Nature, 2024, doi:10.1007/s00220-024-05143-y. short: L. Erdös, V. Riabov, Communications in Mathematical Physics 405 (2024). corr_author: '1' date_created: 2024-11-17T23:01:46Z date_published: 2024-12-01T00:00:00Z date_updated: 2026-04-07T12:32:19Z day: '01' ddc: - '510' department: - _id: LaEr doi: 10.1007/s00220-024-05143-y external_id: arxiv: - '2403.10359' isi: - '001348943900004' pmid: - '39526190' file: - access_level: open_access checksum: c9ae0ea195bd39b8b3a630d492fb00dc content_type: application/pdf creator: dernst date_created: 2024-11-18T08:15:07Z date_updated: 2024-11-18T08:15:07Z file_id: '18562' file_name: 2024_CommMathPhysics_Erdoes.pdf file_size: 1426046 relation: main_file success: 1 file_date_updated: 2024-11-18T08:15:07Z has_accepted_license: '1' intvolume: ' 405' isi: 1 issue: '12' language: - iso: eng month: '12' oa: 1 oa_version: Published Version pmid: 1 publication: Communications in Mathematical Physics publication_identifier: eissn: - 1432-0916 issn: - 0010-3616 publication_status: published publisher: Springer Nature quality_controlled: '1' related_material: record: - id: '20575' relation: dissertation_contains status: public scopus_import: '1' status: public title: Eigenstate Thermalization Hypothesis for Wigner-type matrices tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 405 year: '2024' ... --- OA_place: publisher OA_type: gold _id: '18556' abstract: - lang: eng text: Given a finite set, A ⊆ ℝ², and a subset, B ⊆ A, the MST-ratio is the combined length of the minimum spanning trees of B and A⧵B divided by the length of the minimum spanning tree of A. The question of the supremum, over all sets A, of the maximum, over all subsets B, is related to the Steiner ratio, and we prove this sup-max is between 2.154 and 2.427. Restricting ourselves to 2-dimensional lattices, we prove that the sup-max is 2, while the inf-max is 1.25. By some margin the most difficult of these results is the upper bound for the inf-max, which we prove by showing that the hexagonal lattice cannot have MST-ratio larger than 1.25. acknowledgement: This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme, grant no. 788183, from the Wittgenstein Prize, Austrian Science Fund (FWF), grant no. Z 342-N31, and from the DFG Collaborative Research Center TRR 109, "Discretization in Geometry and Dynamics", Austrian Science Fund (FWF), grant no. I 02979-N35. alternative_title: - LIPIcs article_number: '3' article_processing_charge: Yes arxiv: 1 author: - first_name: Sebastiano full_name: Cultrera di Montesano, Sebastiano id: 34D2A09C-F248-11E8-B48F-1D18A9856A87 last_name: Cultrera di Montesano orcid: 0000-0001-6249-0832 - first_name: Ondrej full_name: Draganov, Ondrej id: 2B23F01E-F248-11E8-B48F-1D18A9856A87 last_name: Draganov orcid: 0000-0003-0464-3823 - first_name: Herbert full_name: Edelsbrunner, Herbert id: 3FB178DA-F248-11E8-B48F-1D18A9856A87 last_name: Edelsbrunner orcid: 0000-0002-9823-6833 - first_name: Morteza full_name: Saghafian, Morteza id: f86f7148-b140-11ec-9577-95435b8df824 last_name: Saghafian citation: ama: 'Cultrera di Montesano S, Draganov O, Edelsbrunner H, Saghafian M. The Euclidean MST-ratio for bi-colored lattices. In: 32nd International Symposium on Graph Drawing and Network Visualization. Vol 320. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2024. doi:10.4230/LIPIcs.GD.2024.3' apa: 'Cultrera di Montesano, S., Draganov, O., Edelsbrunner, H., & Saghafian, M. (2024). The Euclidean MST-ratio for bi-colored lattices. In 32nd International Symposium on Graph Drawing and Network Visualization (Vol. 320). Vienna, Austria: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. https://doi.org/10.4230/LIPIcs.GD.2024.3' chicago: Cultrera di Montesano, Sebastiano, Ondrej Draganov, Herbert Edelsbrunner, and Morteza Saghafian. “The Euclidean MST-Ratio for Bi-Colored Lattices.” In 32nd International Symposium on Graph Drawing and Network Visualization, Vol. 320. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2024. https://doi.org/10.4230/LIPIcs.GD.2024.3. ieee: S. Cultrera di Montesano, O. Draganov, H. Edelsbrunner, and M. Saghafian, “The Euclidean MST-ratio for bi-colored lattices,” in 32nd International Symposium on Graph Drawing and Network Visualization, Vienna, Austria, 2024, vol. 320. ista: 'Cultrera di Montesano S, Draganov O, Edelsbrunner H, Saghafian M. 2024. The Euclidean MST-ratio for bi-colored lattices. 32nd International Symposium on Graph Drawing and Network Visualization. GD: Graph Drawing and Network Visualization, LIPIcs, vol. 320, 3.' mla: Cultrera di Montesano, Sebastiano, et al. “The Euclidean MST-Ratio for Bi-Colored Lattices.” 32nd International Symposium on Graph Drawing and Network Visualization, vol. 320, 3, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2024, doi:10.4230/LIPIcs.GD.2024.3. short: S. Cultrera di Montesano, O. Draganov, H. Edelsbrunner, M. Saghafian, in:, 32nd International Symposium on Graph Drawing and Network Visualization, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2024. conference: end_date: 2024-09-20 location: Vienna, Austria name: 'GD: Graph Drawing and Network Visualization' start_date: 2024-09-18 corr_author: '1' date_created: 2024-11-17T23:01:47Z date_published: 2024-10-28T00:00:00Z date_updated: 2025-12-02T13:50:50Z day: '28' ddc: - '510' department: - _id: HeEd doi: 10.4230/LIPIcs.GD.2024.3 ec_funded: 1 external_id: arxiv: - '2403.10204' isi: - '001540278400001' file: - access_level: open_access checksum: 5f9b35e115c3d375e99be78da9054cb4 content_type: application/pdf creator: dernst date_created: 2024-11-18T07:49:25Z date_updated: 2024-11-18T07:49:25Z file_id: '18560' file_name: 2024_LIPIcs_CultreradiMontesano.pdf file_size: 908541 relation: main_file success: 1 file_date_updated: 2024-11-18T07:49:25Z has_accepted_license: '1' intvolume: ' 320' isi: 1 language: - iso: eng month: '10' oa: 1 oa_version: Published Version project: - _id: 266A2E9E-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '788183' name: Alpha Shape Theory Extended - _id: 268116B8-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: Z00342 name: Mathematics, Computer Science - _id: 2561EBF4-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: I02979-N35 name: Persistence and stability of geometric complexes publication: 32nd International Symposium on Graph Drawing and Network Visualization publication_identifier: isbn: - '9783959773430' issn: - 1868-8969 publication_status: published publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik quality_controlled: '1' scopus_import: '1' status: public title: The Euclidean MST-ratio for bi-colored lattices tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: conference user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 320 year: '2024' ...