---
OA_place: publisher
_id: '18104'
abstract:
- lang: eng
  text: "We introduce a new all-electric platform, that strong couples light to mechanical
    motion\r\nby ensuring that the external environmental coupling dominates over
    internal mechanical\r\ndissipation. The system only has three everyday components:
    AC, DC, and a fip-chip, in which\r\na metallized silicon nitride membrane is fipped
    on top of the device under test. This everyday\r\nelectromechanical device can
    be operated at low or room temperature and has 10000× lower\r\ninsertion loss
    than a comparable commercial quartz crystal, achieves a position imprecision\r\nmatching
    state-of-the-art optical interferometer, and enables remote cooling of mechanical\r\nmotion.
    The spatial properties of higher order mechanical modes are a promising feature
    for\r\nreconstructing unknown charge distributions.\r\n"
acknowledged_ssus:
- _id: NanoFab
- _id: M-Shop
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Denise
  full_name: Puglia, Denise
  id: 4D495994-AE37-11E9-AC72-31CAE5697425
  last_name: Puglia
  orcid: 0000-0003-1144-2763
citation:
  ama: 'Puglia D. Everyday electromechanics: Capacitive strong coupling to mechanical
    motion. 2024. doi:<a href="https://doi.org/10.15479/at:ista:18104">10.15479/at:ista:18104</a>'
  apa: 'Puglia, D. (2024). <i>Everyday electromechanics: Capacitive strong coupling
    to mechanical motion</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/at:ista:18104">https://doi.org/10.15479/at:ista:18104</a>'
  chicago: 'Puglia, Denise. “Everyday Electromechanics: Capacitive Strong Coupling
    to Mechanical Motion.” Institute of Science and Technology Austria, 2024. <a href="https://doi.org/10.15479/at:ista:18104">https://doi.org/10.15479/at:ista:18104</a>.'
  ieee: 'D. Puglia, “Everyday electromechanics: Capacitive strong coupling to mechanical
    motion,” Institute of Science and Technology Austria, 2024.'
  ista: 'Puglia D. 2024. Everyday electromechanics: Capacitive strong coupling to
    mechanical motion. Institute of Science and Technology Austria.'
  mla: 'Puglia, Denise. <i>Everyday Electromechanics: Capacitive Strong Coupling to
    Mechanical Motion</i>. Institute of Science and Technology Austria, 2024, doi:<a
    href="https://doi.org/10.15479/at:ista:18104">10.15479/at:ista:18104</a>.'
  short: 'D. Puglia, Everyday Electromechanics: Capacitive Strong Coupling to Mechanical
    Motion, Institute of Science and Technology Austria, 2024.'
corr_author: '1'
date_created: 2024-09-20T12:13:30Z
date_published: 2024-09-20T00:00:00Z
date_updated: 2026-04-07T13:22:10Z
day: '20'
ddc:
- '530'
degree_awarded: PhD
department:
- _id: GradSch
- _id: AnHi
doi: 10.15479/at:ista:18104
file:
- access_level: open_access
  checksum: 7969263451b2356bfa0924725aa9de10
  content_type: application/pdf
  creator: cchlebak
  date_created: 2024-09-20T12:07:48Z
  date_updated: 2025-05-20T22:30:05Z
  embargo: 2025-05-20
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  file_name: PhD_DPuglia_Final.pdf
  file_size: 10778238
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  checksum: 98dfe7675775e30efffa03f7ff7c091b
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  creator: cchlebak
  date_created: 2024-09-20T12:13:09Z
  date_updated: 2025-05-20T22:30:05Z
  embargo_to: open_access
  file_id: '18106'
  file_name: PhD_DPuglia_Thesis.zip
  file_size: 385419748
  relation: source_file
file_date_updated: 2025-05-20T22:30:05Z
has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/4.0/
month: '09'
oa: 1
oa_version: Published Version
page: '63'
project:
- _id: 0aa3608a-070f-11eb-9043-e9cd8a2bd931
  grant_number: P33692
  name: Cavity electromechanics across a quantum phase transition
- _id: 62843413-2b32-11ec-9570-c4ec6eabfae7
  grant_number: '26088'
  name: Surface Charge and Tunneling Multi-Mode Imaging
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '18143'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Andrew P
  full_name: Higginbotham, Andrew P
  id: 4AD6785A-F248-11E8-B48F-1D18A9856A87
  last_name: Higginbotham
  orcid: 0000-0003-2607-2363
title: 'Everyday electromechanics: Capacitive strong coupling to mechanical motion'
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2024'
...
---
OA_place: repository
_id: '18143'
abstract:
- lang: eng
  text: "Strong optomechanical coupling -- a regime where mechanical motion is damped\r\nby
    environmental radiation -- has traditionally required demanding experimental\r\ningredients
    such as superconducting resonators, high-quality optical cavities,\r\nor large
    magnetic fields. Here we demonstrate a room temperature, cavity-free,\r\nall-electric
    device reaching this regime at radio frequencies, enabled by a\r\nmechanically
    compliant parallel-plate capacitor with a nanoscale plate\r\nseparation and an
    aspect ratio exceeding 1,000. The device has four orders of\r\nmagnitude lower
    insertion loss than a comparable commercial quartz crystal, and\r\nachieves a
    position imprecision rivaling an optical interferometer. With the\r\nhelp of a
    back-action isolation scheme, we observe radiative cooling of\r\nmechanical motion
    by a remote cryogenic load. This work provides a\r\ntechnologically accessible
    route to high-precision sensing, transduction, and\r\nsignal processing."
article_number: '2407.15314'
article_processing_charge: No
arxiv: 1
author:
- first_name: Denise
  full_name: Puglia, Denise
  id: 4D495994-AE37-11E9-AC72-31CAE5697425
  last_name: Puglia
  orcid: 0000-0003-1144-2763
- first_name: Rachel H
  full_name: Odessey, Rachel H
  id: 9a7a5123-8972-11ed-ae7b-dd1f2af457bd
  last_name: Odessey
- first_name: Peter S.
  full_name: Burns, Peter S.
  last_name: Burns
- first_name: Niklas
  full_name: Luhmann, Niklas
  last_name: Luhmann
- first_name: Silvan
  full_name: Schmid, Silvan
  last_name: Schmid
- first_name: Andrew P
  full_name: Higginbotham, Andrew P
  id: 4AD6785A-F248-11E8-B48F-1D18A9856A87
  last_name: Higginbotham
  orcid: 0000-0003-2607-2363
citation:
  ama: Puglia D, Odessey RH, Burns PS, Luhmann N, Schmid S, Higginbotham AP. Room
    temperature, cavity-free capacitive strong coupling to mechanical  motion. <i>arXiv</i>.
    doi:<a href="https://doi.org/10.48550/arXiv.2407.15314">10.48550/arXiv.2407.15314</a>
  apa: Puglia, D., Odessey, R. H., Burns, P. S., Luhmann, N., Schmid, S., &#38; Higginbotham,
    A. P. (n.d.). Room temperature, cavity-free capacitive strong coupling to mechanical 
    motion. <i>arXiv</i>. <a href="https://doi.org/10.48550/arXiv.2407.15314">https://doi.org/10.48550/arXiv.2407.15314</a>
  chicago: Puglia, Denise, Rachel H Odessey, Peter S. Burns, Niklas Luhmann, Silvan
    Schmid, and Andrew P Higginbotham. “Room Temperature, Cavity-Free Capacitive Strong
    Coupling to Mechanical  Motion.” <i>ArXiv</i>, n.d. <a href="https://doi.org/10.48550/arXiv.2407.15314">https://doi.org/10.48550/arXiv.2407.15314</a>.
  ieee: D. Puglia, R. H. Odessey, P. S. Burns, N. Luhmann, S. Schmid, and A. P. Higginbotham,
    “Room temperature, cavity-free capacitive strong coupling to mechanical  motion,”
    <i>arXiv</i>. .
  ista: Puglia D, Odessey RH, Burns PS, Luhmann N, Schmid S, Higginbotham AP. Room
    temperature, cavity-free capacitive strong coupling to mechanical  motion. arXiv,
    2407.15314.
  mla: Puglia, Denise, et al. “Room Temperature, Cavity-Free Capacitive Strong Coupling
    to Mechanical  Motion.” <i>ArXiv</i>, 2407.15314, doi:<a href="https://doi.org/10.48550/arXiv.2407.15314">10.48550/arXiv.2407.15314</a>.
  short: D. Puglia, R.H. Odessey, P.S. Burns, N. Luhmann, S. Schmid, A.P. Higginbotham,
    ArXiv (n.d.).
corr_author: '1'
date_created: 2024-09-26T06:58:27Z
date_published: 2024-08-24T00:00:00Z
date_updated: 2026-05-27T22:30:31Z
day: '24'
department:
- _id: AnHi
doi: 10.48550/arXiv.2407.15314
external_id:
  arxiv:
  - '2407.15314'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2407.15314
month: '08'
oa: 1
oa_version: Preprint
project:
- _id: 62843413-2b32-11ec-9570-c4ec6eabfae7
  grant_number: '26088'
  name: Surface Charge and Tunneling Multi-Mode Imaging
- _id: 0aa3608a-070f-11eb-9043-e9cd8a2bd931
  grant_number: P33692
  name: Cavity electromechanics across a quantum phase transition
publication: arXiv
publication_status: draft
related_material:
  record:
  - id: '19026'
    relation: later_version
    status: public
  - id: '18104'
    relation: dissertation_contains
    status: public
status: public
title: Room temperature, cavity-free capacitive strong coupling to mechanical  motion
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2024'
...
---
OA_place: publisher
_id: '18642'
abstract:
- lang: eng
  text: "This thesis consists of two pieces of work in the broader feld of computational
    biology,\r\nboth of which are methods for the analysis of large scale biological
    data, implemented in\r\nefcient software.\r\nChapter 2 introduces a statistical
    software for causal discovery and inference from observed\r\ngenetic marker and
    phenotypic trait data. We explore in simulation how well the method\r\ncan fne-map
    genetic efects, fnd the correct causal structure among tens of traits and\r\nmillions
    of genetic markers, and infer the causal efect size for the discovered causal\r\nrelations.
    We then apply the method to 8 million markers and 17 traits from the UK\r\nBiobank
    and show that many relationships found with other methods are likely due to\r\nthe
    efects of hidden confounders.\r\nChapter 3 describes how this method can be applied
    to longitudinal data. I show how one\r\ncan incorporate the background knowledge
    present in the known order of measurements to\r\nimprove the accuracy of the causal
    discovery process, and explore the method’s ability to\r\nidentify age specifc
    genetic efects, and how the error rates of this recovery are infuenced\r\nby missing
    data due to diferent censoring mechanisms.\r\nChapter 4 introduces a statistical
    software for the comparison of chromatin contact maps\r\nbased on the structural
    similarity index. We explore the robustness of the method to\r\nnoise and size
    diferences of the compared maps, show how it can measure evolutionary\r\nconservation
    of topological features by providing a similarity ranking of syntenic regions,\r\nand
    fnally how it can detect alterations in 3D genome structure due to genetic mutations\r\nin
    samples of medical relevance.\r\n"
acknowledgement: "I would like to thank the Swiss National Science Foundation for
  funding parts of this work\r\nthrough the Eccellenza Grant \"Improving estimation
  and prediction of common complex\r\ndisease risk\" with grant number PCEGP3_181181."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Nick N
  full_name: Machnik, Nick N
  id: 3591A0AA-F248-11E8-B48F-1D18A9856A87
  last_name: Machnik
  orcid: 0000-0001-6617-9742
citation:
  ama: Machnik NN. Algorithms for causal learning and comparative analysis for genomic
    data. 2024. doi:<a href="https://doi.org/10.15479/at:ista:18642">10.15479/at:ista:18642</a>
  apa: Machnik, N. N. (2024). <i>Algorithms for causal learning and comparative analysis
    for genomic data</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/at:ista:18642">https://doi.org/10.15479/at:ista:18642</a>
  chicago: Machnik, Nick N. “Algorithms for Causal Learning and Comparative Analysis
    for Genomic Data.” Institute of Science and Technology Austria, 2024. <a href="https://doi.org/10.15479/at:ista:18642">https://doi.org/10.15479/at:ista:18642</a>.
  ieee: N. N. Machnik, “Algorithms for causal learning and comparative analysis for
    genomic data,” Institute of Science and Technology Austria, 2024.
  ista: Machnik NN. 2024. Algorithms for causal learning and comparative analysis
    for genomic data. Institute of Science and Technology Austria.
  mla: Machnik, Nick N. <i>Algorithms for Causal Learning and Comparative Analysis
    for Genomic Data</i>. Institute of Science and Technology Austria, 2024, doi:<a
    href="https://doi.org/10.15479/at:ista:18642">10.15479/at:ista:18642</a>.
  short: N.N. Machnik, Algorithms for Causal Learning and Comparative Analysis for
    Genomic Data, Institute of Science and Technology Austria, 2024.
corr_author: '1'
date_created: 2024-12-10T13:49:15Z
date_published: 2024-12-11T00:00:00Z
date_updated: 2026-04-07T13:23:06Z
day: '11'
ddc:
- '576'
degree_awarded: PhD
department:
- _id: GradSch
- _id: MaRo
doi: 10.15479/at:ista:18642
file:
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  checksum: d45e4d170f9a70a1f69b44b99bd058e4
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  creator: nmachnik
  date_created: 2024-12-11T11:59:54Z
  date_updated: 2025-06-12T22:30:02Z
  embargo: 2025-06-12
  file_id: '18649'
  file_name: NickMachnikThesisFinal_pdfa_conv.pdf
  file_size: 12845009
  relation: main_file
- access_level: closed
  checksum: f88c9acc62002395ec4dcbdb5eea8b82
  content_type: application/zip
  creator: nmachnik
  date_created: 2024-12-11T11:59:34Z
  date_updated: 2025-06-12T22:30:02Z
  embargo_to: open_access
  file_id: '18650'
  file_name: thesis.zip
  file_size: 14189810
  relation: source_file
file_date_updated: 2025-06-12T22:30:02Z
has_accepted_license: '1'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: '138'
project:
- _id: 9B8D11D6-BA93-11EA-9121-9846C619BF3A
  grant_number: PCEGP3_181181
  name: Improving estimation and prediction of common complex disease risk
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '18648'
    relation: part_of_dissertation
    status: public
  - id: '8707'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Matthew Richard
  full_name: Robinson, Matthew Richard
  id: E5D42276-F5DA-11E9-8E24-6303E6697425
  last_name: Robinson
  orcid: 0000-0001-8982-8813
title: Algorithms for causal learning and comparative analysis for genomic data
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2024'
...
---
OA_place: repository
OA_type: free access
_id: '18648'
abstract:
- lang: eng
  text: "Statistical causal learning in genomics relies on the instrumental variable
    method of\r\nMendelian Randomization (MR). Currently, an overwhelming number of
    MR studies\r\npurport to show causal relationships among a wide range of risk
    factors and outcomes.\r\nHere, we show that selecting instrument variables from
    genome-wide association study\r\nestimates leads to high false discovery rates
    for many MR approaches, which can be\r\ngreatly reduced by employing a graphical
    inference approach which: (i) explicitly tests\r\ninstrumental variable assumptions;
    (ii) distinguishes direct from indirect factors in very\r\nhigh-dimensional data;
    (iii) discriminates pleiotropic from trait-specific markers, controlling for LD
    genome-wide; (iv) accommodates rare variants and binary outcomes in a\r\nprincipled
    way; and (v) identifies potential unobserved latent confounding. For 17 traits\r\nand
    8.4M variants recorded for 458,747 individuals in the UK Biobank, we show that\r\nstandard
    MR analysis gives an abundance of findings that disappear under stringent\r\nassumption
    checks, with many relationships reflecting potential unmeasured confounding. This
    implies that mixtures of temporal precedence and potential for reverse-causality\r\nprohibit
    understanding the underlying nature of phenotypic and genetic correlations in\r\nbiobank
    data. We propose that well-curated longitudinal records are likely needed and\r\nthat
    our approach provides a first-step toward robust principled screening for potential\r\ncausal
    links.\r\n"
acknowledged_ssus:
- _id: ScienComp
acknowledgement: "We thank Zoltan Kutalik and members of the Robinson group \r\nat
  ISTA for their comments, which improved this manuscript. This work was funded \r\nby
  a research collaboration agreement between Boehringer Ingelheim and the research
  \r\ngroup of MRR at the Institute of Science and Technology Austria. Additional
  funding \r\nwas also provided by an SNSF Eccellenza Grant to MRR (PCEGP3-181181),
  and by \r\ncore funding from the Institute of Science and Technology Austria. We
  would like \r\nto acknowledge the participants and investigators of the UK Biobank
  study. High- \r\nperformance computing was supported by the Scientific Service Units
  (SSU) of IST \r\nAustria through resources provided by Scientific Computing (SciComp). "
article_processing_charge: No
author:
- first_name: Nick N
  full_name: Machnik, Nick N
  id: 3591A0AA-F248-11E8-B48F-1D18A9856A87
  last_name: Machnik
  orcid: 0000-0001-6617-9742
- first_name: Seyed Mahdi
  full_name: Mahmoudi, Seyed Mahdi
  id: b9f6d5ef-7774-11eb-a47f-df2c75c02ee7
  last_name: Mahmoudi
- first_name: Malgorzata
  full_name: Borczyk, Malgorzata
  last_name: Borczyk
- first_name: Ilse
  full_name: Krätschmer, Ilse
  id: 30d4014e-7753-11eb-b44b-db6d61112e73
  last_name: Krätschmer
  orcid: 0000-0002-5636-9259
- first_name: Markus J.
  full_name: Bauer, Markus J.
  last_name: Bauer
- first_name: Matthew Richard
  full_name: Robinson, Matthew Richard
  id: E5D42276-F5DA-11E9-8E24-6303E6697425
  last_name: Robinson
  orcid: 0000-0001-8982-8813
citation:
  ama: Machnik NN, Mahmoudi SM, Borczyk M, Krätschmer I, Bauer MJ, Robinson MR. Causal
    inference for multiple risk factors and diseases from genomics data. <i>bioRxiv</i>.
    2024. doi:<a href="https://doi.org/10.1101/2023.12.06.570392">10.1101/2023.12.06.570392</a>
  apa: Machnik, N. N., Mahmoudi, S. M., Borczyk, M., Krätschmer, I., Bauer, M. J.,
    &#38; Robinson, M. R. (2024). Causal inference for multiple risk factors and diseases
    from genomics data. <i>bioRxiv</i>. <a href="https://doi.org/10.1101/2023.12.06.570392">https://doi.org/10.1101/2023.12.06.570392</a>
  chicago: Machnik, Nick N, Seyed Mahdi Mahmoudi, Malgorzata Borczyk, Ilse Krätschmer,
    Markus J. Bauer, and Matthew Richard Robinson. “Causal Inference for Multiple
    Risk Factors and Diseases from Genomics Data.” <i>BioRxiv</i>, 2024. <a href="https://doi.org/10.1101/2023.12.06.570392">https://doi.org/10.1101/2023.12.06.570392</a>.
  ieee: N. N. Machnik, S. M. Mahmoudi, M. Borczyk, I. Krätschmer, M. J. Bauer, and
    M. R. Robinson, “Causal inference for multiple risk factors and diseases from
    genomics data,” <i>bioRxiv</i>. 2024.
  ista: Machnik NN, Mahmoudi SM, Borczyk M, Krätschmer I, Bauer MJ, Robinson MR. 2024.
    Causal inference for multiple risk factors and diseases from genomics data. bioRxiv,
    <a href="https://doi.org/10.1101/2023.12.06.570392">10.1101/2023.12.06.570392</a>.
  mla: Machnik, Nick N., et al. “Causal Inference for Multiple Risk Factors and Diseases
    from Genomics Data.” <i>BioRxiv</i>, 2024, doi:<a href="https://doi.org/10.1101/2023.12.06.570392">10.1101/2023.12.06.570392</a>.
  short: N.N. Machnik, S.M. Mahmoudi, M. Borczyk, I. Krätschmer, M.J. Bauer, M.R.
    Robinson, BioRxiv (2024).
corr_author: '1'
date_created: 2024-12-11T10:42:59Z
date_published: 2024-08-10T00:00:00Z
date_updated: 2026-05-27T22:30:33Z
day: '10'
department:
- _id: MaRo
doi: 10.1101/2023.12.06.570392
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/2023.12.06.570392
month: '08'
oa: 1
oa_version: Preprint
project:
- _id: 9B8D11D6-BA93-11EA-9121-9846C619BF3A
  grant_number: PCEGP3_181181
  name: Improving estimation and prediction of common complex disease risk
- _id: bd936e6f-d553-11ed-ba76-a82299f63e8c
  grant_number: '590359'
  name: Advanced statistical modelling to facilitate more accurate characterisation
    of disease phenotypes, improved genetic mapping, and effective therapeutic hypothesis
    generation
publication: bioRxiv
publication_status: published
related_material:
  record:
  - id: '18642'
    relation: dissertation_contains
    status: public
status: public
title: Causal inference for multiple risk factors and diseases from genomics data
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: preprint
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2024'
...
---
OA_embargo: '12'
OA_place: publisher
_id: '18574'
abstract:
- lang: eng
  text: "Biological vision is unlike a camera; rather than transmitting light information
    faithfully, early\r\nvisual circuits process the visual scene to convey only the
    relevant information in an efficient\r\nmanner. Consequentially, the nature of
    this visual processing then depends on what is the\r\nrelevant information in
    a scene and on the notion of efficiency. In this work, I study how visual\r\nprocessing
    is modulated by two different variations in the visual scene. First, I discovered
    that\r\nin the mouse (Mus musculus) retina, Retinal Ganglion Cells in the upper
    and lower visual\r\nfield have differences in the center surround structure of
    their receptive fields. Comparison\r\nwith models of efficient coding show that
    this adaptation likely evolved to cope with the\r\nbrightness gradient from the
    sky to the ground that is pervasive in natural scenes. In the\r\nsecond project,
    I study how the downstream neurons in the Superior Colliculus dynamically\r\nchange
    their temporal selectivity depending on the ambient luminance and behavioral state.\r\nAs
    the scene gets darker or when the animal is is less aroused, the neuronal responses
    get\r\nlaggier, while still maintaining their relative timing with respect to
    the population. Overall, this\r\nwork emphasises the need to understand visual
    processing in the context of specific demands\r\nof the animal in its the environment.
    The adaptive changes in the visual system, from the\r\nretinal ganglion cells
    to the superior colliculus, highlight the intricate ways in which biological\r\nvision
    optimizes the processing of visual information.\r\n"
acknowledged_ssus:
- _id: Bio
- _id: ScienComp
- _id: PreCl
- _id: LifeSc
- _id: M-Shop
- _id: E-Lib
acknowledgement: "This work would have been impossible without the Scientific Service
  Units of IST Austria. The resources and expertise provided by Scientific Computing
  (especially Alois Schlögl), the MIBA Machine Shop (especially Todor Asenov), the
  Preclinical Facility (especially Freyja Langer), the Library, the Lab Support Facility
  and the Imaging and Optics Facility were the essential bedrock I could build upon.
  I would also like to thank IT support at ISTA for powering through remote work and
  a cyberattack.\r\nI am grateful for having been funded initially by the European
  Union Horizon 2020 Marie Skłodowska-Curie grant 665385 and later by Prof. Maximilian
  Joesch's the European Research Council Starting (756502) and Consolidator (101086580)
  Grants."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Divyansh
  full_name: Gupta, Divyansh
  id: 2A485EBE-F248-11E8-B48F-1D18A9856A87
  last_name: Gupta
  orcid: 0000-0001-7400-6665
citation:
  ama: Gupta D. Visual adaptations to natural statistics. 2024. doi:<a href="https://doi.org/10.15479/at:ista:18574">10.15479/at:ista:18574</a>
  apa: Gupta, D. (2024). <i>Visual adaptations to natural statistics</i>. Institute
    of Science and Technology Austria. <a href="https://doi.org/10.15479/at:ista:18574">https://doi.org/10.15479/at:ista:18574</a>
  chicago: Gupta, Divyansh. “Visual Adaptations to Natural Statistics.” Institute
    of Science and Technology Austria, 2024. <a href="https://doi.org/10.15479/at:ista:18574">https://doi.org/10.15479/at:ista:18574</a>.
  ieee: D. Gupta, “Visual adaptations to natural statistics,” Institute of Science
    and Technology Austria, 2024.
  ista: Gupta D. 2024. Visual adaptations to natural statistics. Institute of Science
    and Technology Austria.
  mla: Gupta, Divyansh. <i>Visual Adaptations to Natural Statistics</i>. Institute
    of Science and Technology Austria, 2024, doi:<a href="https://doi.org/10.15479/at:ista:18574">10.15479/at:ista:18574</a>.
  short: D. Gupta, Visual Adaptations to Natural Statistics, Institute of Science
    and Technology Austria, 2024.
corr_author: '1'
date_created: 2024-11-20T21:30:44Z
date_published: 2024-11-22T00:00:00Z
date_updated: 2026-04-07T13:24:48Z
day: '22'
ddc:
- '573'
degree_awarded: PhD
department:
- _id: GradSch
- _id: MaJö
doi: 10.15479/at:ista:18574
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month: '11'
oa: 1
oa_version: Published Version
page: '86'
project:
- _id: bdaf81a8-d553-11ed-ba76-c95961984540
  grant_number: '101086580'
  name: 'Action Selection in the Midbrain: Neuromodulation of Visuomotor Senses'
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
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  call_identifier: H2020
  grant_number: '756502'
  name: Circuits of Visual Attention
publication_identifier:
  isbn:
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  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
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    status: public
  - id: '12370'
    relation: research_data
    status: public
status: public
supervisor:
- first_name: Maximilian A
  full_name: Jösch, Maximilian A
  id: 2BD278E6-F248-11E8-B48F-1D18A9856A87
  last_name: Jösch
  orcid: 0000-0002-3937-1330
title: Visual adaptations to natural statistics
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type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2024'
...
---
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abstract:
- lang: eng
  text: "Spatial omics technologies are enriching our understanding of complex biological
    samples, by\r\nallowing us to study their molecular composition while preserving
    the spatial relationships\r\nbetween molecules in their native context. As the
    field continues to advance, there are\r\ntechnical challenges that need to be
    addressed in order to take full advantage of the spatial\r\ncapabilities of these
    methods. In this work, I present two technical developments that I\r\nestablished
    for multiplexed error robust FISH (MERFISH) throughout my PhD: (1) pushing the\r\nspatial
    resolution limits to the nanoscale, and (2) adding rich tissue context to the
    mouse brain\r\ntranscriptome. To achieve nanoscale resolution with MERFISH in
    cultured cells, I combined it\r\nwith stimulated emission depletion (STED) and
    expansion microscopy (ExM) to achieve a\r\nspatial resolution as low as ~20 nm,
    and explored the compatibility of MERFISH with singlemolecule localization microscopy
    (SMLM) techniques. To visualize targeted mRNAs in mouse\r\nbrain tissue, I applied
    the comprehensive analysis of tissues across scales (CATS) toolbox, which\r\nprovides
    an unbiased morphological readout by labeling the extracellular domain. I\r\nsuccessfully
    established this method, which we call CATS-MERFISH-ExM, to work with thick\r\nmouse
    brain slices, being able to extract transcriptomics information with 3D tissue
    context.\r\nCATS-MERFISH-ExM enabled us to identify cell types and further visualize
    the subcellular\r\ndistribution of transcripts in mouse brain tissue, shedding
    light on the neuropil-specific\r\ntranscriptome. This method provides integrated
    information on cellular structure and\r\ntranscriptomes in situ, and could potentially
    be applied with other modalities, opening new\r\navenues for scientific discovery. "
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
- _id: PreCl
- _id: M-Shop
- _id: ScienComp
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Nathalie
  full_name: Agudelo Duenas, Nathalie
  id: 40E7F008-F248-11E8-B48F-1D18A9856A87
  last_name: Agudelo Duenas
citation:
  ama: Agudelo Duenas N. Visualizing the neuronal transcriptional landscape with tissue
    context. 2024. doi:<a href="https://doi.org/10.15479/at:ista:18471">10.15479/at:ista:18471</a>
  apa: Agudelo Duenas, N. (2024). <i>Visualizing the neuronal transcriptional landscape
    with tissue context</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/at:ista:18471">https://doi.org/10.15479/at:ista:18471</a>
  chicago: Agudelo Duenas, Nathalie. “Visualizing the Neuronal Transcriptional Landscape
    with Tissue Context.” Institute of Science and Technology Austria, 2024. <a href="https://doi.org/10.15479/at:ista:18471">https://doi.org/10.15479/at:ista:18471</a>.
  ieee: N. Agudelo Duenas, “Visualizing the neuronal transcriptional landscape with
    tissue context,” Institute of Science and Technology Austria, 2024.
  ista: Agudelo Duenas N. 2024. Visualizing the neuronal transcriptional landscape
    with tissue context. Institute of Science and Technology Austria.
  mla: Agudelo Duenas, Nathalie. <i>Visualizing the Neuronal Transcriptional Landscape
    with Tissue Context</i>. Institute of Science and Technology Austria, 2024, doi:<a
    href="https://doi.org/10.15479/at:ista:18471">10.15479/at:ista:18471</a>.
  short: N. Agudelo Duenas, Visualizing the Neuronal Transcriptional Landscape with
    Tissue Context, Institute of Science and Technology Austria, 2024.
corr_author: '1'
date_created: 2024-10-26T20:02:42Z
date_published: 2024-10-28T00:00:00Z
date_updated: 2026-04-14T08:34:37Z
day: '28'
ddc:
- '570'
degree_awarded: PhD
department:
- _id: GradSch
- _id: JoDa
doi: 10.15479/at:ista:18471
ec_funded: 1
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has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '10'
oa: 1
oa_version: Published Version
page: '97'
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
- _id: 2548AE96-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: W1232
  name: Molecular Drug Targets
publication_identifier:
  isbn:
  - 978-3-99078-044-2
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
status: public
supervisor:
- first_name: Johann G
  full_name: Danzl, Johann G
  id: 42EFD3B6-F248-11E8-B48F-1D18A9856A87
  last_name: Danzl
  orcid: 0000-0001-8559-3973
title: Visualizing the neuronal transcriptional landscape with tissue context
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2024'
...
---
OA_place: publisher
OA_type: hybrid
_id: '17148'
abstract:
- lang: eng
  text: During neural tube (NT) development, the notochord induces an organizer, the
    floorplate, which secretes Sonic Hedgehog (SHH) to pattern neural progenitors.
    Conversely, NT organoids (NTOs) from embryonic stem cells (ESCs) spontaneously
    form floorplates without the notochord, demonstrating that stem cells can self-organize
    without embryonic inducers. Here, we investigated floorplate self-organization
    in clonal mouse NTOs. Expression of the floorplate marker FOXA2 was initially
    spatially scattered before resolving into multiple clusters, which underwent competition
    and sorting, resulting in a stable “winning” floorplate. We identified that BMP
    signaling governed long-range cluster competition. FOXA2+ clusters expressed BMP4,
    suppressing FOXA2 in receiving cells while simultaneously expressing the BMP-inhibitor
    NOGGIN, promoting cluster persistence. Noggin mutation perturbed floorplate formation
    in NTOs and in the NT in vivo at mid/hindbrain regions, demonstrating how the
    floorplate can form autonomously without the notochord. Identifying the pathways
    governing organizer self-organization is critical for harnessing the developmental
    plasticity of stem cells in tissue engineering.
acknowledgement: We thank P. Pasierbek, A.C. Moreno, T. Lendl, and K. Aumayr for microscopy
  support; G. Schmauss for FACS support; M. Novatchkova for assistance with Bioinformatic
  analyses; J. Ahel, A. Polikarpova, S. Horer, E. Cesare, and E. Norouzi for technical
  assistance; A. Meinhardt for supervision; DRESDEN-concept Genome Center, A. Vogt,
  A. Sommer, and the Vienna BioCenter NGS facility for RNA sequencing. We are grateful
  to M. Placzek and E. Martí for discussions about the floorplate; to S. Shvartsman
  for valuable input; to A. Aszodi, W. Masselink, and S. Raiders for advice on statistical
  analyses; to J. Cornwall Scoones, G. Martello, and Tanaka lab members for critical
  reading of the manuscript; E. Bassat and E. Chatzidaki for contributing schematics;
  and to K. Lust for support. This project has received funding from the European
  Research Council (ERC) under the European Union’s Horizon 2020 research and innovation
  programme (grant agreement ERC AdG 742046) to E.M.T. This research was funded in
  whole or in part by the Austrian Science Fund (FWF) (10.55776/F7803-B) (Stem Cell
  Modulation) to E.M.T. and A.K., Sir Henry Wellcome postdoctoral fellowship to H.T.S.,
  ELBE fellowship to K.I., and National Science Foundation (US) Phy 2013131 to E.S.
  The A.K. lab is also supported by ISTA and the European Research Council under Horizon
  Europe grant 101044579, and S.L. is supported by Gesellschaft für Forschungsförderung
  Niederösterreich m.b.H. fellowship SC19-011. This work was supported in part by
  the Francis Crick Institute, which receives its core funding from Cancer Research
  UK (CC001051), the UK Medical Research Council (CC001051), and the Wellcome Trust
  (CC001051). For the purpose of open access, the authors have applied a CC BY public
  copyright license to any author accepted manuscript (AAM) version arising from this
  submission.
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Teresa
  full_name: Krammer, Teresa
  last_name: Krammer
- first_name: Hannah T.
  full_name: Stuart, Hannah T.
  last_name: Stuart
- first_name: Elena
  full_name: Gromberg, Elena
  last_name: Gromberg
- first_name: Keisuke
  full_name: Ishihara, Keisuke
  last_name: Ishihara
- first_name: Dillon
  full_name: Cislo, Dillon
  last_name: Cislo
- first_name: Manuela
  full_name: Melchionda, Manuela
  last_name: Melchionda
- first_name: Fernando
  full_name: Becerril Perez, Fernando
  last_name: Becerril Perez
- first_name: Jingkui
  full_name: Wang, Jingkui
  last_name: Wang
- first_name: Elena
  full_name: Costantini, Elena
  last_name: Costantini
- first_name: Stefanie
  full_name: Rus, Stefanie
  id: 4D9EC9B6-F248-11E8-B48F-1D18A9856A87
  last_name: Rus
  orcid: 0000-0001-8703-1093
- first_name: Laura
  full_name: Arbanas, Laura
  last_name: Arbanas
- first_name: Alexandra
  full_name: Hörmann, Alexandra
  last_name: Hörmann
- first_name: Ralph A.
  full_name: Neumüller, Ralph A.
  last_name: Neumüller
- first_name: Nicola
  full_name: Elvassore, Nicola
  last_name: Elvassore
- first_name: Eric
  full_name: Siggia, Eric
  last_name: Siggia
- first_name: James
  full_name: Briscoe, James
  last_name: Briscoe
- first_name: Anna
  full_name: Kicheva, Anna
  id: 3959A2A0-F248-11E8-B48F-1D18A9856A87
  last_name: Kicheva
  orcid: 0000-0003-4509-4998
- first_name: Elly M.
  full_name: Tanaka, Elly M.
  last_name: Tanaka
citation:
  ama: Krammer T, Stuart HT, Gromberg E, et al. Mouse neural tube organoids self-organize
    floorplate through BMP-mediated cluster competition. <i>Developmental Cell</i>.
    2024;59(15):1940-1953.e10. doi:<a href="https://doi.org/10.1016/j.devcel.2024.04.021">10.1016/j.devcel.2024.04.021</a>
  apa: Krammer, T., Stuart, H. T., Gromberg, E., Ishihara, K., Cislo, D., Melchionda,
    M., … Tanaka, E. M. (2024). Mouse neural tube organoids self-organize floorplate
    through BMP-mediated cluster competition. <i>Developmental Cell</i>. Elsevier.
    <a href="https://doi.org/10.1016/j.devcel.2024.04.021">https://doi.org/10.1016/j.devcel.2024.04.021</a>
  chicago: Krammer, Teresa, Hannah T. Stuart, Elena Gromberg, Keisuke Ishihara, Dillon
    Cislo, Manuela Melchionda, Fernando Becerril Perez, et al. “Mouse Neural Tube
    Organoids Self-Organize Floorplate through BMP-Mediated Cluster Competition.”
    <i>Developmental Cell</i>. Elsevier, 2024. <a href="https://doi.org/10.1016/j.devcel.2024.04.021">https://doi.org/10.1016/j.devcel.2024.04.021</a>.
  ieee: T. Krammer <i>et al.</i>, “Mouse neural tube organoids self-organize floorplate
    through BMP-mediated cluster competition,” <i>Developmental Cell</i>, vol. 59,
    no. 15. Elsevier, p. 1940–1953.e10, 2024.
  ista: Krammer T, Stuart HT, Gromberg E, Ishihara K, Cislo D, Melchionda M, Becerril
    Perez F, Wang J, Costantini E, Rus S, Arbanas L, Hörmann A, Neumüller RA, Elvassore
    N, Siggia E, Briscoe J, Kicheva A, Tanaka EM. 2024. Mouse neural tube organoids
    self-organize floorplate through BMP-mediated cluster competition. Developmental
    Cell. 59(15), 1940–1953.e10.
  mla: Krammer, Teresa, et al. “Mouse Neural Tube Organoids Self-Organize Floorplate
    through BMP-Mediated Cluster Competition.” <i>Developmental Cell</i>, vol. 59,
    no. 15, Elsevier, 2024, p. 1940–1953.e10, doi:<a href="https://doi.org/10.1016/j.devcel.2024.04.021">10.1016/j.devcel.2024.04.021</a>.
  short: T. Krammer, H.T. Stuart, E. Gromberg, K. Ishihara, D. Cislo, M. Melchionda,
    F. Becerril Perez, J. Wang, E. Costantini, S. Rus, L. Arbanas, A. Hörmann, R.A.
    Neumüller, N. Elvassore, E. Siggia, J. Briscoe, A. Kicheva, E.M. Tanaka, Developmental
    Cell 59 (2024) 1940–1953.e10.
date_created: 2024-06-16T22:01:07Z
date_published: 2024-08-01T00:00:00Z
date_updated: 2026-05-27T22:31:10Z
day: '01'
ddc:
- '570'
department:
- _id: AnKi
doi: 10.1016/j.devcel.2024.04.021
external_id:
  isi:
  - '001289684800001'
  pmid:
  - '38776925'
file:
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has_accepted_license: '1'
intvolume: '        59'
isi: 1
issue: '15'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '08'
oa: 1
oa_version: Published Version
page: 1940-1953.e10
pmid: 1
project:
- _id: bd7e737f-d553-11ed-ba76-d69ffb5ee3aa
  grant_number: '101044579'
  name: Mechanisms of tissue size regulation in spinal cord development
- _id: 9B9B39FA-BA93-11EA-9121-9846C619BF3A
  grant_number: SC19-011
  name: The regulatory logic of pattern formation in the vertebrate dorsal neural
    tube
publication: Developmental Cell
publication_identifier:
  eissn:
  - 1878-1551
  issn:
  - 1534-5807
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
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scopus_import: '1'
status: public
title: Mouse neural tube organoids self-organize floorplate through BMP-mediated cluster
  competition
tmp:
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  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 59
year: '2024'
...
---
APC_amount: 804 EUR
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '18601'
abstract:
- lang: eng
  text: "Geometrically controlled stem cell differentiation promotes reproducible
    pattern formation. Here, we present a protocol to fabricate elastomeric stencils
    for patterned stem cell differentiation. We describe procedures for using photolithography
    to produce molds, followed by molding polydimethylsiloxane (PDMS) to obtain stencils
    with through holes. We then provide instructions for culturing cells on stencils
    and, finally, removing stencils to allow colony growth and cell migration. This
    approach yields reproducible two-dimensional organoids tailored for quantitative
    studies of growth and pattern formation.\r\nFor complete details on the use and
    execution of this protocol, please refer to Lehr et al.1"
acknowledged_ssus:
- _id: NanoFab
acknowledgement: We thank the nanofabrication facility at ISTA for technical assistance.
  Work in the A.K. lab is supported by ISTA, the European Research Council under Horizon
  Europe (grant 101044579), and the Austrian Science Fund (FWF) (grant https://doi.org/10.55776/F78).
  S.L. is supported by Gesellschaft für Forschungsförderung Niederösterreich m.b.H.
  fellowship SC19-011.
article_number: '103187'
article_processing_charge: Yes
article_type: original
author:
- first_name: Stefanie
  full_name: Rus, Stefanie
  id: 4D9EC9B6-F248-11E8-B48F-1D18A9856A87
  last_name: Rus
  orcid: 0000-0001-8703-1093
- first_name: Jack
  full_name: Merrin, Jack
  id: 4515C308-F248-11E8-B48F-1D18A9856A87
  last_name: Merrin
  orcid: 0000-0001-5145-4609
- first_name: Monika Aleksandra
  full_name: Kulig, Monika Aleksandra
  id: 3331f5ae-e896-11ec-af79-eeb79769bcb7
  last_name: Kulig
- first_name: Thomas
  full_name: Minchington, Thomas
  id: 7d1648cb-19e9-11eb-8e7a-f8c037fb3e3f
  last_name: Minchington
- first_name: Anna
  full_name: Kicheva, Anna
  id: 3959A2A0-F248-11E8-B48F-1D18A9856A87
  last_name: Kicheva
  orcid: 0000-0003-4509-4998
citation:
  ama: Rus S, Merrin J, Kulig MA, Minchington T, Kicheva A. Protocol for fabricating
    elastomeric stencils for patterned stem cell differentiation. <i>STAR Protocols</i>.
    2024;5(4). doi:<a href="https://doi.org/10.1016/j.xpro.2024.103187">10.1016/j.xpro.2024.103187</a>
  apa: Rus, S., Merrin, J., Kulig, M. A., Minchington, T., &#38; Kicheva, A. (2024).
    Protocol for fabricating elastomeric stencils for patterned stem cell differentiation.
    <i>STAR Protocols</i>. Elsevier. <a href="https://doi.org/10.1016/j.xpro.2024.103187">https://doi.org/10.1016/j.xpro.2024.103187</a>
  chicago: Rus, Stefanie, Jack Merrin, Monika Aleksandra Kulig, Thomas Minchington,
    and Anna Kicheva. “Protocol for Fabricating Elastomeric Stencils for Patterned
    Stem Cell Differentiation.” <i>STAR Protocols</i>. Elsevier, 2024. <a href="https://doi.org/10.1016/j.xpro.2024.103187">https://doi.org/10.1016/j.xpro.2024.103187</a>.
  ieee: S. Rus, J. Merrin, M. A. Kulig, T. Minchington, and A. Kicheva, “Protocol
    for fabricating elastomeric stencils for patterned stem cell differentiation,”
    <i>STAR Protocols</i>, vol. 5, no. 4. Elsevier, 2024.
  ista: Rus S, Merrin J, Kulig MA, Minchington T, Kicheva A. 2024. Protocol for fabricating
    elastomeric stencils for patterned stem cell differentiation. STAR Protocols.
    5(4), 103187.
  mla: Rus, Stefanie, et al. “Protocol for Fabricating Elastomeric Stencils for Patterned
    Stem Cell Differentiation.” <i>STAR Protocols</i>, vol. 5, no. 4, 103187, Elsevier,
    2024, doi:<a href="https://doi.org/10.1016/j.xpro.2024.103187">10.1016/j.xpro.2024.103187</a>.
  short: S. Rus, J. Merrin, M.A. Kulig, T. Minchington, A. Kicheva, STAR Protocols
    5 (2024).
corr_author: '1'
date_created: 2024-12-01T23:01:53Z
date_published: 2024-12-20T00:00:00Z
date_updated: 2026-05-27T22:31:09Z
day: '20'
ddc:
- '570'
department:
- _id: AnKi
- _id: NanoFab
doi: 10.1016/j.xpro.2024.103187
external_id:
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oa: 1
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pmid: 1
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  grant_number: '101044579'
  name: Mechanisms of tissue size regulation in spinal cord development
- _id: 9B9B39FA-BA93-11EA-9121-9846C619BF3A
  grant_number: SC19-011
  name: The regulatory logic of pattern formation in the vertebrate dorsal neural
    tube
publication: STAR Protocols
publication_identifier:
  eissn:
  - 2666-1667
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
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scopus_import: '1'
status: public
title: Protocol for fabricating elastomeric stencils for patterned stem cell differentiation
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2024'
...
---
APC_amount: 3145,39 EUR
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '17890'
abstract:
- lang: eng
  text: Our understanding of the molecular pathways that regulate oogenesis and define
    cellular identity in the Arthropod female reproductive system and the extent of
    their conservation is currently very limited. This is due to the focus on model
    systems, including Drosophila and Daphnia, which do not reflect the observed diversity
    of morphologies, reproductive modes, and sex chromosome systems. We use single-nucleus
    RNA and ATAC sequencing to produce a comprehensive single nucleus atlas of the
    adult Artemia franciscana female reproductive system. We map our data to the Fly
    Cell Atlas single-nucleus dataset of the Drosophila melanogaster ovary, shedding
    light on the conserved regulatory programs between the two distantly related Arthropod
    species. We identify the major cell types known to be present in the Artemia ovary,
    including germ cells, follicle cells, and ovarian muscle cells. Additionally,
    we use the germ cells to explore gene regulation and expression of the Z chromosome
    during meiosis, highlighting its unique regulatory dynamics and allowing us to
    explore the presence of meiotic sex chromosome silencing in this group.
acknowledged_ssus:
- _id: ScienComp
acknowledgement: "We thank the Vicoso group for their valuable comments on the earlier
  draft of the manuscript. We would also like to thank the Vienna BioCenter Next Generation
  Sequencing (NGS) facility staff, and in particular, Thomas Grentzinger for his support
  with the handling and sequencing of the samples, the scientific computing unit at
  ISTA for the computational resources, Brittney Wick for the help with hosting our
  data on the UCSC Cell Browser, and Lora B. Sweeney for her valuable input at the
  different stages of the project.\r\nThis research was funded by the Austrian science
  fund (FWF), as part of the SFB Meiosis consortium https://sfbmeiosis.org/, grant
  ID FWF SFB F88-10) to BV. "
article_number: e1011376
article_processing_charge: Yes
article_type: original
author:
- first_name: Marwan N
  full_name: Elkrewi, Marwan N
  id: 0B46FACA-A8E1-11E9-9BD3-79D1E5697425
  last_name: Elkrewi
  orcid: 0000-0002-5328-7231
- first_name: Beatriz
  full_name: Vicoso, Beatriz
  id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
  last_name: Vicoso
  orcid: 0000-0002-4579-8306
citation:
  ama: Elkrewi MN, Vicoso B. Single-nucleus atlas of the Artemia female reproductive
    system suggests germline repression of the Z chromosome. <i>PLoS Genetics</i>.
    2024;20(8). doi:<a href="https://doi.org/10.1371/journal.pgen.1011376">10.1371/journal.pgen.1011376</a>
  apa: Elkrewi, M. N., &#38; Vicoso, B. (2024). Single-nucleus atlas of the Artemia
    female reproductive system suggests germline repression of the Z chromosome. <i>PLoS
    Genetics</i>. Public Library of Science. <a href="https://doi.org/10.1371/journal.pgen.1011376">https://doi.org/10.1371/journal.pgen.1011376</a>
  chicago: Elkrewi, Marwan N, and Beatriz Vicoso. “Single-Nucleus Atlas of the Artemia
    Female Reproductive System Suggests Germline Repression of the Z Chromosome.”
    <i>PLoS Genetics</i>. Public Library of Science, 2024. <a href="https://doi.org/10.1371/journal.pgen.1011376">https://doi.org/10.1371/journal.pgen.1011376</a>.
  ieee: M. N. Elkrewi and B. Vicoso, “Single-nucleus atlas of the Artemia female reproductive
    system suggests germline repression of the Z chromosome,” <i>PLoS Genetics</i>,
    vol. 20, no. 8. Public Library of Science, 2024.
  ista: Elkrewi MN, Vicoso B. 2024. Single-nucleus atlas of the Artemia female reproductive
    system suggests germline repression of the Z chromosome. PLoS Genetics. 20(8),
    e1011376.
  mla: Elkrewi, Marwan N., and Beatriz Vicoso. “Single-Nucleus Atlas of the Artemia
    Female Reproductive System Suggests Germline Repression of the Z Chromosome.”
    <i>PLoS Genetics</i>, vol. 20, no. 8, e1011376, Public Library of Science, 2024,
    doi:<a href="https://doi.org/10.1371/journal.pgen.1011376">10.1371/journal.pgen.1011376</a>.
  short: M.N. Elkrewi, B. Vicoso, PLoS Genetics 20 (2024).
corr_author: '1'
date_created: 2024-09-08T22:01:11Z
date_published: 2024-08-30T00:00:00Z
date_updated: 2026-05-27T22:31:20Z
day: '30'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1371/journal.pgen.1011376
external_id:
  isi:
  - '001304090200001'
  pmid:
  - '39213449'
file:
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intvolume: '        20'
isi: 1
issue: '8'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 3AC91DDA-15DF-11EA-824D-93A3E7B544D1
  call_identifier: FWF
  name: FWF Open Access Fund
- _id: 34ae1506-11ca-11ed-8bc3-c14f4c474396
  grant_number: F8810
  name: The highjacking of meiosis for asexual reproduction
publication: PLoS Genetics
publication_identifier:
  eissn:
  - 1553-7404
  issn:
  - 1553-7390
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
related_material:
  link:
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    url: https://github.com/Melkrewi/Artemia-snRNAseq-Project
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scopus_import: '1'
status: public
title: Single-nucleus atlas of the Artemia female reproductive system suggests germline
  repression of the Z chromosome
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 20
year: '2024'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '15009'
abstract:
- lang: eng
  text: Since the commercialization of brine shrimp (genus Artemia) in the 1950s,
    this lineage, and in particular the model species Artemia franciscana, has been
    the subject of extensive research. However, our understanding of the genetic mechanisms
    underlying various aspects of their reproductive biology, including sex determination,
    is still lacking. This is partly due to the scarcity of genomic resources for
    Artemia species and crustaceans in general. Here, we present a chromosome-level
    genome assembly of A. franciscana (Kellogg 1906), from the Great Salt Lake, United
    States. The genome is 1 GB, and the majority of the genome (81%) is scaffolded
    into 21 linkage groups using a previously published high-density linkage map.
    We performed coverage and FST analyses using male and female genomic and transcriptomic
    reads to quantify the extent of differentiation between the Z and W chromosomes.
    Additionally, we quantified the expression levels in male and female heads and
    gonads and found further evidence for dosage compensation in this species.
article_number: evae006
article_processing_charge: Yes
article_type: original
author:
- first_name: Vincent K
  full_name: Bett, Vincent K
  id: 57854184-AAE0-11E9-8D04-98D6E5697425
  last_name: Bett
- first_name: Ariana
  full_name: Macon, Ariana
  id: 2A0848E2-F248-11E8-B48F-1D18A9856A87
  last_name: Macon
- first_name: Beatriz
  full_name: Vicoso, Beatriz
  id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
  last_name: Vicoso
  orcid: 0000-0002-4579-8306
- first_name: Marwan N
  full_name: Elkrewi, Marwan N
  id: 0B46FACA-A8E1-11E9-9BD3-79D1E5697425
  last_name: Elkrewi
  orcid: 0000-0002-5328-7231
citation:
  ama: Bett VK, Macon A, Vicoso B, Elkrewi MN. Chromosome-level assembly of Artemia
    franciscana sheds light on sex chromosome differentiation. <i>Genome Biology and
    Evolution</i>. 2024;16(1). doi:<a href="https://doi.org/10.1093/gbe/evae006">10.1093/gbe/evae006</a>
  apa: Bett, V. K., Macon, A., Vicoso, B., &#38; Elkrewi, M. N. (2024). Chromosome-level
    assembly of Artemia franciscana sheds light on sex chromosome differentiation.
    <i>Genome Biology and Evolution</i>. Oxford University Press. <a href="https://doi.org/10.1093/gbe/evae006">https://doi.org/10.1093/gbe/evae006</a>
  chicago: Bett, Vincent K, Ariana Macon, Beatriz Vicoso, and Marwan N Elkrewi. “Chromosome-Level
    Assembly of Artemia Franciscana Sheds Light on Sex Chromosome Differentiation.”
    <i>Genome Biology and Evolution</i>. Oxford University Press, 2024. <a href="https://doi.org/10.1093/gbe/evae006">https://doi.org/10.1093/gbe/evae006</a>.
  ieee: V. K. Bett, A. Macon, B. Vicoso, and M. N. Elkrewi, “Chromosome-level assembly
    of Artemia franciscana sheds light on sex chromosome differentiation,” <i>Genome
    Biology and Evolution</i>, vol. 16, no. 1. Oxford University Press, 2024.
  ista: Bett VK, Macon A, Vicoso B, Elkrewi MN. 2024. Chromosome-level assembly of
    Artemia franciscana sheds light on sex chromosome differentiation. Genome Biology
    and Evolution. 16(1), evae006.
  mla: Bett, Vincent K., et al. “Chromosome-Level Assembly of Artemia Franciscana
    Sheds Light on Sex Chromosome Differentiation.” <i>Genome Biology and Evolution</i>,
    vol. 16, no. 1, evae006, Oxford University Press, 2024, doi:<a href="https://doi.org/10.1093/gbe/evae006">10.1093/gbe/evae006</a>.
  short: V.K. Bett, A. Macon, B. Vicoso, M.N. Elkrewi, Genome Biology and Evolution
    16 (2024).
corr_author: '1'
date_created: 2024-02-18T23:01:02Z
date_published: 2024-01-20T00:00:00Z
date_updated: 2026-05-27T22:31:20Z
day: '20'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1093/gbe/evae006
external_id:
  isi:
  - '001153952800001'
  pmid:
  - '38245839'
file:
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  checksum: 106a40f10443b2e7ba66749844ebbdf1
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  creator: dernst
  date_created: 2024-02-26T09:54:59Z
  date_updated: 2024-02-26T09:54:59Z
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  success: 1
file_date_updated: 2024-02-26T09:54:59Z
has_accepted_license: '1'
intvolume: '        16'
isi: 1
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
pmid: 1
publication: Genome Biology and Evolution
publication_identifier:
  eissn:
  - 1759-6653
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
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scopus_import: '1'
status: public
title: Chromosome-level assembly of Artemia franciscana sheds light on sex chromosome
  differentiation
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 16
year: '2024'
...
---
APC_amount: 3782,54
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '17183'
abstract:
- lang: eng
  text: "The photon blockade breakdown in a continuously driven cavity QED system
    has been proposed as a prime example for a first-order driven-dissipative quantum
    phase transition. However, the predicted scaling from a microscopic behavior—dominated
    by quantum fluctuations—to a macroscopic one—characterized by stable phases—and
    the associated exponents and phase diagram have not been observed so far. In this
    work we couple a single transmon qubit with a fixed coupling strength \U0001D454
    to a superconducting cavity that is in situ bandwidth \U0001D705 tunable to controllably
    approach this thermodynamic limit. Even though the system remains microscopic,
    we observe its behavior becoming increasingly macroscopic as a function of \U0001D454/\U0001D705.
    For the highest realized \U0001D454/\U0001D705 of approximately 287, the system
    switches with a characteristic timescale as long as 6 s between a bright coherent
    state with approximately 8×103 intracavity photons and the vacuum state. This
    exceeds the microscopic timescales by 6 orders of magnitude and approaches the
    perfect hysteresis expected between two macroscopic attractors in the thermodynamic
    limit. These findings and interpretation are qualitatively supported by neoclassical
    theory and large-scale quantum-jump Monte Carlo simulations. Besides shedding
    more light on driven-dissipative physics in the limit of strong light-matter coupling,
    this system might also find applications in quantum sensing and metrology."
acknowledged_ssus:
- _id: M-Shop
acknowledgement: This work has received funding from the Austrian Science Fund (FWF)
  through BeyondC (F7105) and the European Union’s Horizon 2020 research and innovation
  program under Grant Agreement No. 862644 (FETopen QUARTET). A.V. acknowledges support
  from the National Research, Development and Innovation Office of Hungary (NKFIH)
  within the Quantum Information National Laboratory of Hungary. The authors thank
  the MIBA workshop and the Institute of Science and Technology Austria nanofabrication
  facility for technical support. We are grateful to HUN-REN Cloud for providing us
  with suitable computational infrastructure for the simulations.
article_number: '010327'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Riya
  full_name: Sett, Riya
  id: 2E6D040E-F248-11E8-B48F-1D18A9856A87
  last_name: Sett
  orcid: 0000-0001-7641-8348
- first_name: Farid
  full_name: Hassani, Farid
  id: 2AED110C-F248-11E8-B48F-1D18A9856A87
  last_name: Hassani
  orcid: 0000-0001-6937-5773
- first_name: Duc T
  full_name: Phan, Duc T
  id: 29C8C0B4-F248-11E8-B48F-1D18A9856A87
  last_name: Phan
- first_name: Shabir
  full_name: Barzanjeh, Shabir
  id: 2D25E1F6-F248-11E8-B48F-1D18A9856A87
  last_name: Barzanjeh
  orcid: 0000-0003-0415-1423
- first_name: Andras
  full_name: Vukics, Andras
  last_name: Vukics
- first_name: Johannes M
  full_name: Fink, Johannes M
  id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
  last_name: Fink
  orcid: 0000-0001-8112-028X
citation:
  ama: Sett R, Hassani F, Phan DT, Barzanjeh S, Vukics A, Fink JM. Emergent macroscopic
    bistability induced by a single superconducting qubit. <i>PRX Quantum</i>. 2024;5(1).
    doi:<a href="https://doi.org/10.1103/prxquantum.5.010327">10.1103/prxquantum.5.010327</a>
  apa: Sett, R., Hassani, F., Phan, D. T., Barzanjeh, S., Vukics, A., &#38; Fink,
    J. M. (2024). Emergent macroscopic bistability induced by a single superconducting
    qubit. <i>PRX Quantum</i>. American Physical Society. <a href="https://doi.org/10.1103/prxquantum.5.010327">https://doi.org/10.1103/prxquantum.5.010327</a>
  chicago: Sett, Riya, Farid Hassani, Duc T Phan, Shabir Barzanjeh, Andras Vukics,
    and Johannes M Fink. “Emergent Macroscopic Bistability Induced by a Single Superconducting
    Qubit.” <i>PRX Quantum</i>. American Physical Society, 2024. <a href="https://doi.org/10.1103/prxquantum.5.010327">https://doi.org/10.1103/prxquantum.5.010327</a>.
  ieee: R. Sett, F. Hassani, D. T. Phan, S. Barzanjeh, A. Vukics, and J. M. Fink,
    “Emergent macroscopic bistability induced by a single superconducting qubit,”
    <i>PRX Quantum</i>, vol. 5, no. 1. American Physical Society, 2024.
  ista: Sett R, Hassani F, Phan DT, Barzanjeh S, Vukics A, Fink JM. 2024. Emergent
    macroscopic bistability induced by a single superconducting qubit. PRX Quantum.
    5(1), 010327.
  mla: Sett, Riya, et al. “Emergent Macroscopic Bistability Induced by a Single Superconducting
    Qubit.” <i>PRX Quantum</i>, vol. 5, no. 1, 010327, American Physical Society,
    2024, doi:<a href="https://doi.org/10.1103/prxquantum.5.010327">10.1103/prxquantum.5.010327</a>.
  short: R. Sett, F. Hassani, D.T. Phan, S. Barzanjeh, A. Vukics, J.M. Fink, PRX Quantum
    5 (2024).
corr_author: '1'
date_created: 2024-06-27T10:58:06Z
date_published: 2024-02-16T00:00:00Z
date_updated: 2026-05-27T22:31:23Z
day: '16'
ddc:
- '530'
department:
- _id: JoFi
- _id: AnHi
doi: 10.1103/prxquantum.5.010327
ec_funded: 1
external_id:
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  - '2210.14182'
  isi:
  - '001171652500001'
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  success: 1
file_date_updated: 2024-06-28T12:04:43Z
has_accepted_license: '1'
intvolume: '         5'
isi: 1
issue: '1'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
project:
- _id: 237CBA6C-32DE-11EA-91FC-C7463DDC885E
  call_identifier: H2020
  grant_number: '862644'
  name: Quantum readout techniques and technologies
- _id: 3AC91DDA-15DF-11EA-824D-93A3E7B544D1
  call_identifier: FWF
  name: FWF Open Access Fund
- _id: bdb108fd-d553-11ed-ba76-83dc74a9864f
  grant_number: F07105
  name: QUANTUM INFORMATION SYSTEMS BEYOND CLASSICAL CAPABILITIES / P5- Integration
    of Superconducting Quantum Circuits
publication: PRX Quantum
publication_identifier:
  eissn:
  - 2691-3399
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
related_material:
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  - id: '18978'
    relation: research_data
    status: public
  - id: '19533'
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    status: public
scopus_import: '1'
status: public
title: Emergent macroscopic bistability induced by a single superconducting qubit
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2024'
...
---
OA_place: repository
OA_type: green
_id: '14796'
abstract:
- lang: eng
  text: Key innovations are fundamental to biological diversification, but their genetic
    basis is poorly understood. A recent transition from egg-laying to live-bearing
    in marine snails (Littorina spp.) provides the opportunity to study the genetic
    architecture of an innovation that has evolved repeatedly across animals. Individuals
    do not cluster by reproductive mode in a genome-wide phylogeny, but local genealogical
    analysis revealed numerous small genomic regions where all live-bearers carry
    the same core haplotype. Candidate regions show evidence for live-bearer–specific
    positive selection and are enriched for genes that are differentially expressed
    between egg-laying and live-bearing reproductive systems. Ages of selective sweeps
    suggest that live-bearer–specific alleles accumulated over more than 200,000 generations.
    Our results suggest that new functions evolve through the recruitment of many
    alleles rather than in a single evolutionary step.
acknowledgement: "We thank J. Galindo, M. Montaño-Rendón, N. Mikhailova, A. Blakeslee,
  E. Arnason, and P. Kemppainen for providing samples; R. Turney, G. Sotelo, J. Larsson,
  T. Broquet, and S. Loisel for help collecting samples; Science Animated for providing
  the snail cartoons shown in Fig. 1; M. Dunning for help in developing bioinformatic
  pipelines; R. Faria, H. Morales, and V. Sousa for advice; and M. Hahn, J. Slate,
  M. Ravinet, J. Raeymaekers, A. Comeault, and N. Barton for feedback on a draft manuscript.\r\nThis
  work was supported by the Natural Environment Research Council (grant NE/P001610/1
  to R.K.B.), the European Research Council (grant ERC-2015-AdG693030-BARRIERS to
  R.K.B.), the Norwegian Research Council (RCN Project 315287 to A.M.W.), and the
  Swedish Research Council (grant 2020-05385 to E.L.)."
article_processing_charge: No
article_type: original
author:
- first_name: Sean
  full_name: Stankowski, Sean
  id: 43161670-5719-11EA-8025-FABC3DDC885E
  last_name: Stankowski
- first_name: Zuzanna B.
  full_name: Zagrodzka, Zuzanna B.
  last_name: Zagrodzka
- first_name: Martin D.
  full_name: Garlovsky, Martin D.
  last_name: Garlovsky
- first_name: Arka
  full_name: Pal, Arka
  id: 6AAB2240-CA9A-11E9-9C1A-D9D1E5697425
  last_name: Pal
  orcid: 0000-0002-4530-8469
- first_name: Daria
  full_name: Shipilina, Daria
  id: 428A94B0-F248-11E8-B48F-1D18A9856A87
  last_name: Shipilina
  orcid: 0000-0002-1145-9226
- first_name: Diego Fernando
  full_name: Garcia Castillo, Diego Fernando
  id: ae681a14-dc74-11ea-a0a7-c6ef18161701
  last_name: Garcia Castillo
- first_name: Hila
  full_name: Lifchitz, Hila
  id: d6ab5470-2fb3-11ed-8633-986a9b84edac
  last_name: Lifchitz
- first_name: Alan
  full_name: Le Moan, Alan
  last_name: Le Moan
- first_name: Erica
  full_name: Leder, Erica
  last_name: Leder
- first_name: James
  full_name: Reeve, James
  last_name: Reeve
- first_name: Kerstin
  full_name: Johannesson, Kerstin
  last_name: Johannesson
- first_name: Anja M
  full_name: Westram, Anja M
  id: 3C147470-F248-11E8-B48F-1D18A9856A87
  last_name: Westram
  orcid: 0000-0003-1050-4969
- first_name: Roger K.
  full_name: Butlin, Roger K.
  last_name: Butlin
citation:
  ama: Stankowski S, Zagrodzka ZB, Garlovsky MD, et al. The genetic basis of a recent
    transition to live-bearing in marine snails. <i>Science</i>. 2024;383(6678):114-119.
    doi:<a href="https://doi.org/10.1126/science.adi2982">10.1126/science.adi2982</a>
  apa: Stankowski, S., Zagrodzka, Z. B., Garlovsky, M. D., Pal, A., Shipilina, D.,
    Garcia Castillo, D. F., … Butlin, R. K. (2024). The genetic basis of a recent
    transition to live-bearing in marine snails. <i>Science</i>. American Association
    for the Advancement of Science. <a href="https://doi.org/10.1126/science.adi2982">https://doi.org/10.1126/science.adi2982</a>
  chicago: Stankowski, Sean, Zuzanna B. Zagrodzka, Martin D. Garlovsky, Arka Pal,
    Daria Shipilina, Diego Fernando Garcia Castillo, Hila Lifchitz, et al. “The Genetic
    Basis of a Recent Transition to Live-Bearing in Marine Snails.” <i>Science</i>.
    American Association for the Advancement of Science, 2024. <a href="https://doi.org/10.1126/science.adi2982">https://doi.org/10.1126/science.adi2982</a>.
  ieee: S. Stankowski <i>et al.</i>, “The genetic basis of a recent transition to
    live-bearing in marine snails,” <i>Science</i>, vol. 383, no. 6678. American Association
    for the Advancement of Science, pp. 114–119, 2024.
  ista: Stankowski S, Zagrodzka ZB, Garlovsky MD, Pal A, Shipilina D, Garcia Castillo
    DF, Lifchitz H, Le Moan A, Leder E, Reeve J, Johannesson K, Westram AM, Butlin
    RK. 2024. The genetic basis of a recent transition to live-bearing in marine snails.
    Science. 383(6678), 114–119.
  mla: Stankowski, Sean, et al. “The Genetic Basis of a Recent Transition to Live-Bearing
    in Marine Snails.” <i>Science</i>, vol. 383, no. 6678, American Association for
    the Advancement of Science, 2024, pp. 114–19, doi:<a href="https://doi.org/10.1126/science.adi2982">10.1126/science.adi2982</a>.
  short: S. Stankowski, Z.B. Zagrodzka, M.D. Garlovsky, A. Pal, D. Shipilina, D.F.
    Garcia Castillo, H. Lifchitz, A. Le Moan, E. Leder, J. Reeve, K. Johannesson,
    A.M. Westram, R.K. Butlin, Science 383 (2024) 114–119.
corr_author: '1'
date_created: 2024-01-14T23:00:56Z
date_published: 2024-01-05T00:00:00Z
date_updated: 2026-05-27T22:31:22Z
day: '05'
department:
- _id: NiBa
- _id: GradSch
doi: 10.1126/science.adi2982
external_id:
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month: '01'
oa: 1
oa_version: Submitted Version
page: 114-119
pmid: 1
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publisher: American Association for the Advancement of Science
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    relation: press_release
    url: https://ista.ac.at/en/news/the-snail-or-the-egg/
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title: The genetic basis of a recent transition to live-bearing in marine snails
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 383
year: '2024'
...
---
OA_place: repository
OA_type: gold
_id: '18978'
abstract:
- lang: eng
  text: "Data analysis files for the manuscript \"Emergent Macroscopic Bistability
    Induced by a Single Superconducting Qubit\".\r\n\r\nThis contains the raw data
    and the data analysis files for generating the figures in the manuscript.\r\n\r\n
    Figure1 file - The raw data of cavity transmission spectra for 6 different kappas
    are there. They are fitted with input-output theory in the python file.\r\n Figure2
    file - The raw data at 8 MHz kappa are included. all hte figures in figure 2 are
    generated in the python file\r\n Figure3 file - The raw data of PBB single shot
    measurements at all kappas are included. The detailed analysis and the Figure3
    generated for the paper are all in the python analysis file. Also, thefiles containing
    the time-evolution of the intensity from Master Equation solution are included.\r\nFigure4
    file - The raw data at 2.6 MHz for different drive detunings and the corresponding
    analyses are included. And the python file includes the analysis of the experimental
    data as well as approximate neoclassical equations solutions for 2-level and 3-level
    transmons are included.  "
article_processing_charge: No
author:
- first_name: Riya
  full_name: Sett, Riya
  id: 2E6D040E-F248-11E8-B48F-1D18A9856A87
  last_name: Sett
  orcid: 0000-0001-7641-8348
- first_name: Farid
  full_name: Hassani, Farid
  id: 2AED110C-F248-11E8-B48F-1D18A9856A87
  last_name: Hassani
  orcid: 0000-0001-6937-5773
- first_name: Duc T
  full_name: Phan, Duc T
  id: 29C8C0B4-F248-11E8-B48F-1D18A9856A87
  last_name: Phan
- first_name: Shabir
  full_name: Barzanjeh, Shabir
  id: 2D25E1F6-F248-11E8-B48F-1D18A9856A87
  last_name: Barzanjeh
  orcid: 0000-0003-0415-1423
- first_name: Andras
  full_name: Vukics, Andras
  last_name: Vukics
- first_name: Johannes M
  full_name: Fink, Johannes M
  id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
  last_name: Fink
  orcid: 0000-0001-8112-028X
citation:
  ama: Sett R, Hassani F, Phan DT, Barzanjeh S, Vukics A, Fink JM. Data Analysis files
    for “Emergent Macroscopic Bistability Induced by a Single Superconducting Qubit.”
    2024. doi:<a href="https://doi.org/10.5281/ZENODO.10518320">10.5281/ZENODO.10518320</a>
  apa: Sett, R., Hassani, F., Phan, D. T., Barzanjeh, S., Vukics, A., &#38; Fink,
    J. M. (2024). Data Analysis files for “Emergent Macroscopic Bistability Induced
    by a Single Superconducting Qubit.” Zenodo. <a href="https://doi.org/10.5281/ZENODO.10518320">https://doi.org/10.5281/ZENODO.10518320</a>
  chicago: Sett, Riya, Farid Hassani, Duc T Phan, Shabir Barzanjeh, Andras Vukics,
    and Johannes M Fink. “Data Analysis Files for ‘Emergent Macroscopic Bistability
    Induced by a Single Superconducting Qubit.’” Zenodo, 2024. <a href="https://doi.org/10.5281/ZENODO.10518320">https://doi.org/10.5281/ZENODO.10518320</a>.
  ieee: R. Sett, F. Hassani, D. T. Phan, S. Barzanjeh, A. Vukics, and J. M. Fink,
    “Data Analysis files for ‘Emergent Macroscopic Bistability Induced by a Single
    Superconducting Qubit.’” Zenodo, 2024.
  ista: Sett R, Hassani F, Phan DT, Barzanjeh S, Vukics A, Fink JM. 2024. Data Analysis
    files for ‘Emergent Macroscopic Bistability Induced by a Single Superconducting
    Qubit’, Zenodo, <a href="https://doi.org/10.5281/ZENODO.10518320">10.5281/ZENODO.10518320</a>.
  mla: Sett, Riya, et al. <i>Data Analysis Files for “Emergent Macroscopic Bistability
    Induced by a Single Superconducting Qubit.”</i> Zenodo, 2024, doi:<a href="https://doi.org/10.5281/ZENODO.10518320">10.5281/ZENODO.10518320</a>.
  short: R. Sett, F. Hassani, D.T. Phan, S. Barzanjeh, A. Vukics, J.M. Fink, (2024).
corr_author: '1'
date_created: 2025-01-30T08:30:03Z
date_published: 2024-01-16T00:00:00Z
date_updated: 2026-05-27T22:31:23Z
day: '16'
ddc:
- '530'
department:
- _id: JoFi
- _id: AnHi
doi: 10.5281/ZENODO.10518320
has_accepted_license: '1'
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5281/zenodo.10518320
month: '01'
oa: 1
oa_version: Published Version
publisher: Zenodo
related_material:
  record:
  - id: '17183'
    relation: used_in_publication
    status: public
  - id: '19533'
    relation: used_in_publication
    status: public
status: public
title: Data Analysis files for "Emergent Macroscopic Bistability Induced by a Single
  Superconducting Qubit"
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2024'
...
---
_id: '11479'
abstract:
- lang: eng
  text: Understanding population divergence that eventually leads to speciation is
    essential for evolutionary biology. High species diversity in the sea was regarded
    as a paradox when strict allopatry was considered necessary for most speciation
    events because geographical barriers seemed largely absent in the sea, and many
    marine species have high dispersal capacities. Combining genome-wide data with
    demographic modelling to infer the demographic history of divergence has introduced
    new ways to address this classical issue. These models assume an ancestral population
    that splits into two subpopulations diverging according to different scenarios
    that allow tests for periods of gene flow. Models can also test for heterogeneities
    in population sizes and migration rates along the genome to account, respectively,
    for background selection and selection against introgressed ancestry. To investigate
    how barriers to gene flow arise in the sea, we compiled studies modelling the
    demographic history of divergence in marine organisms and extracted preferred
    demographic scenarios together with estimates of demographic parameters. These
    studies show that geographical barriers to gene flow do exist in the sea but that
    divergence can also occur without strict isolation. Heterogeneity of gene flow
    was detected in most population pairs suggesting the predominance of semipermeable
    barriers during divergence. We found a weak positive relationship between the
    fraction of the genome experiencing reduced gene flow and levels of genome-wide
    differentiation. Furthermore, we found that the upper bound of the ‘grey zone
    of speciation’ for our dataset extended beyond that found before, implying that
    gene flow between diverging taxa is possible at higher levels of divergence than
    previously thought. Finally, we list recommendations for further strengthening
    the use of demographic modelling in speciation research. These include a more
    balanced representation of taxa, more consistent and comprehensive modelling,
    clear reporting of results and simulation studies to rule out nonbiological explanations
    for general results.
acknowledgement: 'We greatly thank all the corresponding authors of the studies that
  were included in our synthesis for the sharing of additional data: Thomas Broquet,
  Dmitry Filatov, Quentin Rougemont, Paolo Momigliano, Pierre-Alexandre Gagnaire,
  Carlos Prada, Ahmed Souissi, Michael Møller Hansen, Sylvie Lapègue, Joseph Di Battista,
  Michael Hellberg and Carlos Prada. RKB and ADJ were supported by the European Research
  Council. MR was supported by the Swedish Research Council Vetenskapsrådet (grant
  number 2021-05243; to MR) and Formas (grant number 2019-00882; to KJ and MR), and
  by additional grants from the European Research Council (to RKB) and Vetenskapsrådet
  (to KJ) through the Centre for Marine Evolutionary Biology (https://www.gu.se/en/cemeb-marine-evolutionary-biology).'
article_processing_charge: No
article_type: original
author:
- first_name: Aurélien
  full_name: De Jode, Aurélien
  last_name: De Jode
- first_name: Alan
  full_name: Le Moan, Alan
  last_name: Le Moan
- first_name: Kerstin
  full_name: Johannesson, Kerstin
  last_name: Johannesson
- first_name: Rui
  full_name: Faria, Rui
  last_name: Faria
- first_name: Sean
  full_name: Stankowski, Sean
  id: 43161670-5719-11EA-8025-FABC3DDC885E
  last_name: Stankowski
- first_name: Anja M
  full_name: Westram, Anja M
  id: 3C147470-F248-11E8-B48F-1D18A9856A87
  last_name: Westram
  orcid: 0000-0003-1050-4969
- first_name: Roger K.
  full_name: Butlin, Roger K.
  last_name: Butlin
- first_name: Marina
  full_name: Rafajlović, Marina
  last_name: Rafajlović
- first_name: Christelle
  full_name: Fraisse, Christelle
  id: 32DF5794-F248-11E8-B48F-1D18A9856A87
  last_name: Fraisse
  orcid: 0000-0001-8441-5075
citation:
  ama: De Jode A, Le Moan A, Johannesson K, et al. Ten years of demographic modelling
    of divergence and speciation in the sea. <i>Evolutionary Applications</i>. 2023;16(2):542-559.
    doi:<a href="https://doi.org/10.1111/eva.13428">10.1111/eva.13428</a>
  apa: De Jode, A., Le Moan, A., Johannesson, K., Faria, R., Stankowski, S., Westram,
    A. M., … Fraisse, C. (2023). Ten years of demographic modelling of divergence
    and speciation in the sea. <i>Evolutionary Applications</i>. Wiley. <a href="https://doi.org/10.1111/eva.13428">https://doi.org/10.1111/eva.13428</a>
  chicago: De Jode, Aurélien, Alan Le Moan, Kerstin Johannesson, Rui Faria, Sean Stankowski,
    Anja M Westram, Roger K. Butlin, Marina Rafajlović, and Christelle Fraisse. “Ten
    Years of Demographic Modelling of Divergence and Speciation in the Sea.” <i>Evolutionary
    Applications</i>. Wiley, 2023. <a href="https://doi.org/10.1111/eva.13428">https://doi.org/10.1111/eva.13428</a>.
  ieee: A. De Jode <i>et al.</i>, “Ten years of demographic modelling of divergence
    and speciation in the sea,” <i>Evolutionary Applications</i>, vol. 16, no. 2.
    Wiley, pp. 542–559, 2023.
  ista: De Jode A, Le Moan A, Johannesson K, Faria R, Stankowski S, Westram AM, Butlin
    RK, Rafajlović M, Fraisse C. 2023. Ten years of demographic modelling of divergence
    and speciation in the sea. Evolutionary Applications. 16(2), 542–559.
  mla: De Jode, Aurélien, et al. “Ten Years of Demographic Modelling of Divergence
    and Speciation in the Sea.” <i>Evolutionary Applications</i>, vol. 16, no. 2,
    Wiley, 2023, pp. 542–59, doi:<a href="https://doi.org/10.1111/eva.13428">10.1111/eva.13428</a>.
  short: A. De Jode, A. Le Moan, K. Johannesson, R. Faria, S. Stankowski, A.M. Westram,
    R.K. Butlin, M. Rafajlović, C. Fraisse, Evolutionary Applications 16 (2023) 542–559.
date_created: 2022-07-03T22:01:33Z
date_published: 2023-02-01T00:00:00Z
date_updated: 2025-04-23T08:49:14Z
day: '01'
ddc:
- '576'
department:
- _id: NiBa
- _id: BeVi
doi: 10.1111/eva.13428
external_id:
  isi:
  - '000815663700001'
  pmid:
  - '36793688'
file:
- access_level: open_access
  checksum: d4d6fa9ddf36643af994a6a757919afb
  content_type: application/pdf
  creator: dernst
  date_created: 2023-02-27T07:10:17Z
  date_updated: 2023-02-27T07:10:17Z
  file_id: '12685'
  file_name: 2023_EvolutionaryApplications_DeJode.pdf
  file_size: 2269822
  relation: main_file
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intvolume: '        16'
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issue: '2'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: 542-559
pmid: 1
publication: Evolutionary Applications
publication_identifier:
  eissn:
  - 1752-4571
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Ten years of demographic modelling of divergence and speciation in the sea
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 16
year: '2023'
...
---
_id: '11706'
abstract:
- lang: eng
  text: 'We say that (Formula presented.) if, in every edge coloring (Formula presented.),
    we can find either a 1-colored copy of (Formula presented.) or a 2-colored copy
    of (Formula presented.). The well-known states that the threshold for the property
    (Formula presented.) is equal to (Formula presented.), where (Formula presented.)
    is given by (Formula presented.) for any pair of graphs (Formula presented.) and
    (Formula presented.) with (Formula presented.). In this article, we show the 0-statement
    of the Kohayakawa–Kreuter conjecture for every pair of cycles and cliques. '
acknowledgement: "This work was started at the thematic program GRAPHS@IMPA (January–March
  2018), in Rio de Janeiro. We thank IMPA and the organisers for the hospitality and
  for providing a pleasant research environment. We thank Rob Morris for helpful discussions,
  and the anonymous referees for their careful reading and many helpful suggestions.
  Open Access funding enabled and organized by Projekt DEAL.\r\nA. Liebenau was supported
  by an ARC DECRA Fellowship Grant DE170100789. L. Mattos was supported by CAPES and
  by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany's
  Excellence Strategy – The Berlin Mathematics Research Center MATH+ (EXC-2046/1,
  project ID: 390685689). W. Mendonça was supported by CAPES project 88882.332408/2010-01."
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Anita
  full_name: Liebenau, Anita
  last_name: Liebenau
- first_name: Letícia
  full_name: Mattos, Letícia
  last_name: Mattos
- first_name: Walner
  full_name: Mendonca Dos Santos, Walner
  id: 12c6bd4d-2cd0-11ec-a0da-e28f42f65ebd
  last_name: Mendonca Dos Santos
- first_name: Jozef
  full_name: Skokan, Jozef
  last_name: Skokan
citation:
  ama: Liebenau A, Mattos L, Mendonca dos Santos W, Skokan J. Asymmetric Ramsey properties
    of random graphs involving cliques and cycles. <i>Random Structures and Algorithms</i>.
    2023;62(4):1035-1055. doi:<a href="https://doi.org/10.1002/rsa.21106">10.1002/rsa.21106</a>
  apa: Liebenau, A., Mattos, L., Mendonca dos Santos, W., &#38; Skokan, J. (2023).
    Asymmetric Ramsey properties of random graphs involving cliques and cycles. <i>Random
    Structures and Algorithms</i>. Wiley. <a href="https://doi.org/10.1002/rsa.21106">https://doi.org/10.1002/rsa.21106</a>
  chicago: Liebenau, Anita, Letícia Mattos, Walner Mendonca dos Santos, and Jozef
    Skokan. “Asymmetric Ramsey Properties of Random Graphs Involving Cliques and Cycles.”
    <i>Random Structures and Algorithms</i>. Wiley, 2023. <a href="https://doi.org/10.1002/rsa.21106">https://doi.org/10.1002/rsa.21106</a>.
  ieee: A. Liebenau, L. Mattos, W. Mendonca dos Santos, and J. Skokan, “Asymmetric
    Ramsey properties of random graphs involving cliques and cycles,” <i>Random Structures
    and Algorithms</i>, vol. 62, no. 4. Wiley, pp. 1035–1055, 2023.
  ista: Liebenau A, Mattos L, Mendonca dos Santos W, Skokan J. 2023. Asymmetric Ramsey
    properties of random graphs involving cliques and cycles. Random Structures and
    Algorithms. 62(4), 1035–1055.
  mla: Liebenau, Anita, et al. “Asymmetric Ramsey Properties of Random Graphs Involving
    Cliques and Cycles.” <i>Random Structures and Algorithms</i>, vol. 62, no. 4,
    Wiley, 2023, pp. 1035–55, doi:<a href="https://doi.org/10.1002/rsa.21106">10.1002/rsa.21106</a>.
  short: A. Liebenau, L. Mattos, W. Mendonca dos Santos, J. Skokan, Random Structures
    and Algorithms 62 (2023) 1035–1055.
date_created: 2022-07-31T22:01:49Z
date_published: 2023-07-01T00:00:00Z
date_updated: 2023-10-04T09:38:45Z
day: '01'
ddc:
- '510'
department:
- _id: MaKw
doi: 10.1002/rsa.21106
external_id:
  isi:
  - '000828530400001'
file:
- access_level: open_access
  checksum: 3a5969d0c512aef01c30f3dc81c6d59b
  content_type: application/pdf
  creator: dernst
  date_created: 2023-10-04T09:37:26Z
  date_updated: 2023-10-04T09:37:26Z
  file_id: '14389'
  file_name: 2023_RandomStructureAlgorithms_Liebenau.pdf
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intvolume: '        62'
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issue: '4'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 1035-1055
publication: Random Structures and Algorithms
publication_identifier:
  eissn:
  - 1098-2418
  issn:
  - 1042-9832
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Asymmetric Ramsey properties of random graphs involving cliques and cycles
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type: journal_article
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volume: 62
year: '2023'
...
---
_id: '11741'
abstract:
- lang: eng
  text: Following E. Wigner’s original vision, we prove that sampling the eigenvalue
    gaps within the bulk spectrum of a fixed (deformed) Wigner matrix H yields the
    celebrated Wigner-Dyson-Mehta universal statistics with high probability. Similarly,
    we prove universality for a monoparametric family of deformed Wigner matrices
    H+xA with a deterministic Hermitian matrix A and a fixed Wigner matrix H, just
    using the randomness of a single scalar real random variable x. Both results constitute
    quenched versions of bulk universality that has so far only been proven in annealed
    sense with respect to the probability space of the matrix ensemble.
acknowledgement: "The authors are indebted to Sourav Chatterjee for forwarding the
  very inspiring question that Stephen Shenker originally addressed to him which initiated
  the current paper. They are also grateful that the authors of [23] kindly shared
  their preliminary numerical results in June 2021.\r\nOpen access funding provided
  by Institute of Science and Technology (IST Austria)."
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Giorgio
  full_name: Cipolloni, Giorgio
  id: 42198EFA-F248-11E8-B48F-1D18A9856A87
  last_name: Cipolloni
  orcid: 0000-0002-4901-7992
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
- first_name: Dominik J
  full_name: Schröder, Dominik J
  id: 408ED176-F248-11E8-B48F-1D18A9856A87
  last_name: Schröder
  orcid: 0000-0002-2904-1856
citation:
  ama: Cipolloni G, Erdös L, Schröder DJ. Quenched universality for deformed Wigner
    matrices. <i>Probability Theory and Related Fields</i>. 2023;185:1183–1218. doi:<a
    href="https://doi.org/10.1007/s00440-022-01156-7">10.1007/s00440-022-01156-7</a>
  apa: Cipolloni, G., Erdös, L., &#38; Schröder, D. J. (2023). Quenched universality
    for deformed Wigner matrices. <i>Probability Theory and Related Fields</i>. Springer
    Nature. <a href="https://doi.org/10.1007/s00440-022-01156-7">https://doi.org/10.1007/s00440-022-01156-7</a>
  chicago: Cipolloni, Giorgio, László Erdös, and Dominik J Schröder. “Quenched Universality
    for Deformed Wigner Matrices.” <i>Probability Theory and Related Fields</i>. Springer
    Nature, 2023. <a href="https://doi.org/10.1007/s00440-022-01156-7">https://doi.org/10.1007/s00440-022-01156-7</a>.
  ieee: G. Cipolloni, L. Erdös, and D. J. Schröder, “Quenched universality for deformed
    Wigner matrices,” <i>Probability Theory and Related Fields</i>, vol. 185. Springer
    Nature, pp. 1183–1218, 2023.
  ista: Cipolloni G, Erdös L, Schröder DJ. 2023. Quenched universality for deformed
    Wigner matrices. Probability Theory and Related Fields. 185, 1183–1218.
  mla: Cipolloni, Giorgio, et al. “Quenched Universality for Deformed Wigner Matrices.”
    <i>Probability Theory and Related Fields</i>, vol. 185, Springer Nature, 2023,
    pp. 1183–1218, doi:<a href="https://doi.org/10.1007/s00440-022-01156-7">10.1007/s00440-022-01156-7</a>.
  short: G. Cipolloni, L. Erdös, D.J. Schröder, Probability Theory and Related Fields
    185 (2023) 1183–1218.
corr_author: '1'
date_created: 2022-08-07T22:02:00Z
date_published: 2023-04-01T00:00:00Z
date_updated: 2024-10-09T21:03:02Z
day: '01'
ddc:
- '510'
department:
- _id: LaEr
doi: 10.1007/s00440-022-01156-7
external_id:
  arxiv:
  - '2106.10200'
  isi:
  - '000830344500001'
file:
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language:
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month: '04'
oa: 1
oa_version: Published Version
page: 1183–1218
publication: Probability Theory and Related Fields
publication_identifier:
  eissn:
  - 1432-2064
  issn:
  - 0178-8051
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Quenched universality for deformed Wigner matrices
tmp:
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  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 185
year: '2023'
...
---
_id: '11999'
abstract:
- lang: eng
  text: 'A simple drawing D(G) of a graph G is one where each pair of edges share
    at most one point: either a common endpoint or a proper crossing. An edge e in
    the complement of G can be inserted into D(G) if there exists a simple drawing
    of G+e extending D(G). As a result of Levi’s Enlargement Lemma, if a drawing is
    rectilinear (pseudolinear), that is, the edges can be extended into an arrangement
    of lines (pseudolines), then any edge in the complement of G can be inserted.
    In contrast, we show that it is NP-complete to decide whether one edge can be
    inserted into a simple drawing. This remains true even if we assume that the drawing
    is pseudocircular, that is, the edges can be extended to an arrangement of pseudocircles.
    On the positive side, we show that, given an arrangement of pseudocircles A and
    a pseudosegment σ, it can be decided in polynomial time whether there exists a
    pseudocircle Φσ extending σ for which A∪{Φσ} is again an arrangement of pseudocircles.'
acknowledgement: 'This work was started during the 6th Austrian–Japanese–Mexican–Spanish
  Workshop on Discrete Geometry in June 2019 in Austria. We thank all the participants
  for the good atmosphere as well as discussions on the topic. Also, we thank Jan
  Kynčl for sending us remarks on a preliminary version of this work and an anonymous
  referee for further helpful comments.Alan Arroyo was funded by the Marie Skłodowska-Curie
  grant agreement No 754411. Fabian Klute was partially supported by the Netherlands
  Organisation for Scientific Research (NWO) under project no. 612.001.651 and by
  the Austrian Science Fund (FWF): J-4510. Irene Parada and Birgit Vogtenhuber were
  partially supported by the Austrian Science Fund (FWF): W1230 and within the collaborative
  DACH project Arrangements and Drawings as FWF project I 3340-N35. Irene Parada was
  also partially supported by the Independent Research Fund Denmark grant 2020-2023
  (9131-00044B) Dynamic Network Analysis and by the Margarita Salas Fellowship funded
  by the Ministry of Universities of Spain and the European Union (NextGenerationEU).
  Tilo Wiedera was supported by the German Research Foundation (DFG) grant CH 897/2-2.'
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Alan M
  full_name: Arroyo Guevara, Alan M
  id: 3207FDC6-F248-11E8-B48F-1D18A9856A87
  last_name: Arroyo Guevara
  orcid: 0000-0003-2401-8670
- first_name: Fabian
  full_name: Klute, Fabian
  last_name: Klute
- first_name: Irene
  full_name: Parada, Irene
  last_name: Parada
- first_name: Birgit
  full_name: Vogtenhuber, Birgit
  last_name: Vogtenhuber
- first_name: Raimund
  full_name: Seidel, Raimund
  last_name: Seidel
- first_name: Tilo
  full_name: Wiedera, Tilo
  last_name: Wiedera
citation:
  ama: Arroyo Guevara AM, Klute F, Parada I, Vogtenhuber B, Seidel R, Wiedera T. Inserting
    one edge into a simple drawing is hard. <i>Discrete and Computational Geometry</i>.
    2023;69:745–770. doi:<a href="https://doi.org/10.1007/s00454-022-00394-9">10.1007/s00454-022-00394-9</a>
  apa: Arroyo Guevara, A. M., Klute, F., Parada, I., Vogtenhuber, B., Seidel, R.,
    &#38; Wiedera, T. (2023). Inserting one edge into a simple drawing is hard. <i>Discrete
    and Computational Geometry</i>. Springer Nature. <a href="https://doi.org/10.1007/s00454-022-00394-9">https://doi.org/10.1007/s00454-022-00394-9</a>
  chicago: Arroyo Guevara, Alan M, Fabian Klute, Irene Parada, Birgit Vogtenhuber,
    Raimund Seidel, and Tilo Wiedera. “Inserting One Edge into a Simple Drawing Is
    Hard.” <i>Discrete and Computational Geometry</i>. Springer Nature, 2023. <a href="https://doi.org/10.1007/s00454-022-00394-9">https://doi.org/10.1007/s00454-022-00394-9</a>.
  ieee: A. M. Arroyo Guevara, F. Klute, I. Parada, B. Vogtenhuber, R. Seidel, and
    T. Wiedera, “Inserting one edge into a simple drawing is hard,” <i>Discrete and
    Computational Geometry</i>, vol. 69. Springer Nature, pp. 745–770, 2023.
  ista: Arroyo Guevara AM, Klute F, Parada I, Vogtenhuber B, Seidel R, Wiedera T.
    2023. Inserting one edge into a simple drawing is hard. Discrete and Computational
    Geometry. 69, 745–770.
  mla: Arroyo Guevara, Alan M., et al. “Inserting One Edge into a Simple Drawing Is
    Hard.” <i>Discrete and Computational Geometry</i>, vol. 69, Springer Nature, 2023,
    pp. 745–770, doi:<a href="https://doi.org/10.1007/s00454-022-00394-9">10.1007/s00454-022-00394-9</a>.
  short: A.M. Arroyo Guevara, F. Klute, I. Parada, B. Vogtenhuber, R. Seidel, T. Wiedera,
    Discrete and Computational Geometry 69 (2023) 745–770.
date_created: 2022-08-28T22:02:01Z
date_published: 2023-04-01T00:00:00Z
date_updated: 2025-04-14T07:43:59Z
day: '01'
ddc:
- '510'
department:
- _id: UlWa
doi: 10.1007/s00454-022-00394-9
ec_funded: 1
external_id:
  arxiv:
  - '1909.07347'
  isi:
  - '000840292800001'
file:
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intvolume: '        69'
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language:
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month: '04'
oa: 1
oa_version: Published Version
page: 745–770
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
publication: Discrete and Computational Geometry
publication_identifier:
  eissn:
  - 1432-0444
  issn:
  - 0179-5376
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Inserting one edge into a simple drawing is hard
tmp:
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  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 69
year: '2023'
...
---
_id: '12086'
abstract:
- lang: eng
  text: We present a simple algorithm for computing higher-order Delaunay mosaics
    that works in Euclidean spaces of any finite dimensions. The algorithm selects
    the vertices of the order-k mosaic from incrementally constructed lower-order
    mosaics and uses an algorithm for weighted first-order Delaunay mosaics as a black-box
    to construct the order-k mosaic from its vertices. Beyond this black-box, the
    algorithm uses only combinatorial operations, thus facilitating easy implementation.
    We extend this algorithm to compute higher-order α-shapes and provide open-source
    implementations. We present experimental results for properties of higher-order
    Delaunay mosaics of random point sets.
acknowledgement: Open access funding provided by Austrian Science Fund (FWF). This
  project has received funding from the European Research Council (ERC) under the
  European Union’s Horizon 2020 research and innovation programme, Grant No. 788183,
  from the Wittgenstein Prize, Austrian Science Fund (FWF), Grant No. Z 342-N31, and
  from the DFG Collaborative Research Center TRR 109, ‘Discretization in Geometry
  and Dynamics’, Austrian Science Fund (FWF), Grant No. I 02979-N35.
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
- first_name: Georg F
  full_name: Osang, Georg F
  id: 464B40D6-F248-11E8-B48F-1D18A9856A87
  last_name: Osang
  orcid: 0000-0002-8882-5116
citation:
  ama: Edelsbrunner H, Osang GF. A simple algorithm for higher-order Delaunay mosaics
    and alpha shapes. <i>Algorithmica</i>. 2023;85:277-295. doi:<a href="https://doi.org/10.1007/s00453-022-01027-6">10.1007/s00453-022-01027-6</a>
  apa: Edelsbrunner, H., &#38; Osang, G. F. (2023). A simple algorithm for higher-order
    Delaunay mosaics and alpha shapes. <i>Algorithmica</i>. Springer Nature. <a href="https://doi.org/10.1007/s00453-022-01027-6">https://doi.org/10.1007/s00453-022-01027-6</a>
  chicago: Edelsbrunner, Herbert, and Georg F Osang. “A Simple Algorithm for Higher-Order
    Delaunay Mosaics and Alpha Shapes.” <i>Algorithmica</i>. Springer Nature, 2023.
    <a href="https://doi.org/10.1007/s00453-022-01027-6">https://doi.org/10.1007/s00453-022-01027-6</a>.
  ieee: H. Edelsbrunner and G. F. Osang, “A simple algorithm for higher-order Delaunay
    mosaics and alpha shapes,” <i>Algorithmica</i>, vol. 85. Springer Nature, pp.
    277–295, 2023.
  ista: Edelsbrunner H, Osang GF. 2023. A simple algorithm for higher-order Delaunay
    mosaics and alpha shapes. Algorithmica. 85, 277–295.
  mla: Edelsbrunner, Herbert, and Georg F. Osang. “A Simple Algorithm for Higher-Order
    Delaunay Mosaics and Alpha Shapes.” <i>Algorithmica</i>, vol. 85, Springer Nature,
    2023, pp. 277–95, doi:<a href="https://doi.org/10.1007/s00453-022-01027-6">10.1007/s00453-022-01027-6</a>.
  short: H. Edelsbrunner, G.F. Osang, Algorithmica 85 (2023) 277–295.
corr_author: '1'
date_created: 2022-09-11T22:01:57Z
date_published: 2023-01-01T00:00:00Z
date_updated: 2025-04-23T08:46:48Z
day: '01'
ddc:
- '510'
department:
- _id: HeEd
doi: 10.1007/s00453-022-01027-6
ec_funded: 1
external_id:
  isi:
  - '000846967100001'
  pmid:
  - '36687803'
file:
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  checksum: 71685ca5121f4c837f40c3f8eb50c915
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  date_created: 2023-01-20T10:02:48Z
  date_updated: 2023-01-20T10:02:48Z
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has_accepted_license: '1'
intvolume: '        85'
isi: 1
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 277-295
pmid: 1
project:
- _id: 266A2E9E-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '788183'
  name: Alpha Shape Theory Extended
- _id: 268116B8-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Z00342
  name: Mathematics, Computer Science
- _id: 2561EBF4-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I02979-N35
  name: Persistence and stability of geometric complexes
publication: Algorithmica
publication_identifier:
  eissn:
  - 1432-0541
  issn:
  - 0178-4617
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: A simple algorithm for higher-order Delaunay mosaics and alpha shapes
tmp:
  image: /images/cc_by.png
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  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 85
year: '2023'
...
---
_id: '12087'
abstract:
- lang: eng
  text: Following up on the recent work on lower Ricci curvature bounds for quantum
    systems, we introduce two noncommutative versions of curvature-dimension bounds
    for symmetric quantum Markov semigroups over matrix algebras. Under suitable such
    curvature-dimension conditions, we prove a family of dimension-dependent functional
    inequalities, a version of the Bonnet–Myers theorem and concavity of entropy power
    in the noncommutative setting. We also provide examples satisfying certain curvature-dimension
    conditions, including Schur multipliers over matrix algebras, Herz–Schur multipliers
    over group algebras and generalized depolarizing semigroups.
acknowledgement: H.Z. is supported by the European Union’s Horizon 2020 research and
  innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 754411
  and the Lise Meitner fellowship, Austrian Science Fund (FWF) M3337. M.W. acknowledges
  support from the European Research Council (ERC) under the European Union’s Horizon
  2020 research and innovation programme (Grant Agreement No. 716117) and from the
  Austrian Science Fund (FWF) through grant number F65. Both authors would like to
  thank Jan Maas for fruitful discussions and helpful comments. Open access funding
  provided by Austrian Science Fund (FWF).
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Melchior
  full_name: Wirth, Melchior
  id: 88644358-0A0E-11EA-8FA5-49A33DDC885E
  last_name: Wirth
  orcid: 0000-0002-0519-4241
- first_name: Haonan
  full_name: Zhang, Haonan
  id: D8F41E38-9E66-11E9-A9E2-65C2E5697425
  last_name: Zhang
citation:
  ama: Wirth M, Zhang H. Curvature-dimension conditions for symmetric quantum Markov
    semigroups. <i>Annales Henri Poincare</i>. 2023;24:717-750. doi:<a href="https://doi.org/10.1007/s00023-022-01220-x">10.1007/s00023-022-01220-x</a>
  apa: Wirth, M., &#38; Zhang, H. (2023). Curvature-dimension conditions for symmetric
    quantum Markov semigroups. <i>Annales Henri Poincare</i>. Springer Nature. <a
    href="https://doi.org/10.1007/s00023-022-01220-x">https://doi.org/10.1007/s00023-022-01220-x</a>
  chicago: Wirth, Melchior, and Haonan Zhang. “Curvature-Dimension Conditions for
    Symmetric Quantum Markov Semigroups.” <i>Annales Henri Poincare</i>. Springer
    Nature, 2023. <a href="https://doi.org/10.1007/s00023-022-01220-x">https://doi.org/10.1007/s00023-022-01220-x</a>.
  ieee: M. Wirth and H. Zhang, “Curvature-dimension conditions for symmetric quantum
    Markov semigroups,” <i>Annales Henri Poincare</i>, vol. 24. Springer Nature, pp.
    717–750, 2023.
  ista: Wirth M, Zhang H. 2023. Curvature-dimension conditions for symmetric quantum
    Markov semigroups. Annales Henri Poincare. 24, 717–750.
  mla: Wirth, Melchior, and Haonan Zhang. “Curvature-Dimension Conditions for Symmetric
    Quantum Markov Semigroups.” <i>Annales Henri Poincare</i>, vol. 24, Springer Nature,
    2023, pp. 717–50, doi:<a href="https://doi.org/10.1007/s00023-022-01220-x">10.1007/s00023-022-01220-x</a>.
  short: M. Wirth, H. Zhang, Annales Henri Poincare 24 (2023) 717–750.
corr_author: '1'
date_created: 2022-09-11T22:01:57Z
date_published: 2023-03-01T00:00:00Z
date_updated: 2025-04-23T08:53:05Z
day: '01'
ddc:
- '510'
department:
- _id: JaMa
doi: 10.1007/s00023-022-01220-x
ec_funded: 1
external_id:
  arxiv:
  - '2105.08303'
  isi:
  - '000837499800002'
  pmid:
  - '36950223'
file:
- access_level: open_access
  checksum: 8c7b185eba5ccd92ef55c120f654222c
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  creator: dernst
  date_created: 2023-08-14T11:38:28Z
  date_updated: 2023-08-14T11:38:28Z
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has_accepted_license: '1'
intvolume: '        24'
isi: 1
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 717-750
pmid: 1
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
- _id: eb958bca-77a9-11ec-83b8-c565cb50d8d6
  grant_number: M03337
  name: Curvature-dimension in noncommutative analysis
- _id: 256E75B8-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '716117'
  name: Optimal Transport and Stochastic Dynamics
- _id: fc31cba2-9c52-11eb-aca3-ff467d239cd2
  grant_number: F6504
  name: Taming Complexity in Partial Differential Systems
publication: Annales Henri Poincare
publication_identifier:
  issn:
  - 1424-0637
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Curvature-dimension conditions for symmetric quantum Markov semigroups
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type: journal_article
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volume: 24
year: '2023'
...
---
_id: '12104'
abstract:
- lang: eng
  text: We study ergodic decompositions of Dirichlet spaces under intertwining via
    unitary order isomorphisms. We show that the ergodic decomposition of a quasi-regular
    Dirichlet space is unique up to a unique isomorphism of the indexing space. Furthermore,
    every unitary order isomorphism intertwining two quasi-regular Dirichlet spaces
    is decomposable over their ergodic decompositions up to conjugation via an isomorphism
    of the corresponding indexing spaces.
acknowledgement: Research supported by the Austrian Science Fund (FWF) grant F65 at
  the Institute of Science and Technology Austria and by the European Research Council
  (ERC) (Grant agreement No. 716117 awarded to Prof. Dr. Jan Maas). L.D.S. gratefully
  acknowledges funding of his current position by the Austrian Science Fund (FWF)
  through the ESPRIT Programme (Grant No. 208). M.W. gratefully acknowledges funding
  of his current position by the Austrian Science Fund (FWF) through the ESPRIT Programme
  (Grant No. 156).
article_number: '9'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Lorenzo
  full_name: Dello Schiavo, Lorenzo
  id: ECEBF480-9E4F-11EA-B557-B0823DDC885E
  last_name: Dello Schiavo
  orcid: 0000-0002-9881-6870
- first_name: Melchior
  full_name: Wirth, Melchior
  id: 88644358-0A0E-11EA-8FA5-49A33DDC885E
  last_name: Wirth
  orcid: 0000-0002-0519-4241
citation:
  ama: Dello Schiavo L, Wirth M. Ergodic decompositions of Dirichlet forms under order
    isomorphisms. <i>Journal of Evolution Equations</i>. 2023;23(1). doi:<a href="https://doi.org/10.1007/s00028-022-00859-7">10.1007/s00028-022-00859-7</a>
  apa: Dello Schiavo, L., &#38; Wirth, M. (2023). Ergodic decompositions of Dirichlet
    forms under order isomorphisms. <i>Journal of Evolution Equations</i>. Springer
    Nature. <a href="https://doi.org/10.1007/s00028-022-00859-7">https://doi.org/10.1007/s00028-022-00859-7</a>
  chicago: Dello Schiavo, Lorenzo, and Melchior Wirth. “Ergodic Decompositions of
    Dirichlet Forms under Order Isomorphisms.” <i>Journal of Evolution Equations</i>.
    Springer Nature, 2023. <a href="https://doi.org/10.1007/s00028-022-00859-7">https://doi.org/10.1007/s00028-022-00859-7</a>.
  ieee: L. Dello Schiavo and M. Wirth, “Ergodic decompositions of Dirichlet forms
    under order isomorphisms,” <i>Journal of Evolution Equations</i>, vol. 23, no.
    1. Springer Nature, 2023.
  ista: Dello Schiavo L, Wirth M. 2023. Ergodic decompositions of Dirichlet forms
    under order isomorphisms. Journal of Evolution Equations. 23(1), 9.
  mla: Dello Schiavo, Lorenzo, and Melchior Wirth. “Ergodic Decompositions of Dirichlet
    Forms under Order Isomorphisms.” <i>Journal of Evolution Equations</i>, vol. 23,
    no. 1, 9, Springer Nature, 2023, doi:<a href="https://doi.org/10.1007/s00028-022-00859-7">10.1007/s00028-022-00859-7</a>.
  short: L. Dello Schiavo, M. Wirth, Journal of Evolution Equations 23 (2023).
corr_author: '1'
date_created: 2023-01-08T23:00:53Z
date_published: 2023-01-01T00:00:00Z
date_updated: 2025-04-23T08:45:56Z
day: '01'
ddc:
- '510'
department:
- _id: JaMa
doi: 10.1007/s00028-022-00859-7
ec_funded: 1
external_id:
  isi:
  - '000906214600004'
  pmid:
  - '36597554'
file:
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  creator: dernst
  date_created: 2023-01-20T10:45:06Z
  date_updated: 2023-01-20T10:45:06Z
  file_id: '12325'
  file_name: 2023_JourEvolutionEquations_DelloSchiavo.pdf
  file_size: 422612
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file_date_updated: 2023-01-20T10:45:06Z
has_accepted_license: '1'
intvolume: '        23'
isi: 1
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: fc31cba2-9c52-11eb-aca3-ff467d239cd2
  grant_number: F6504
  name: Taming Complexity in Partial Differential Systems
- _id: 256E75B8-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '716117'
  name: Optimal Transport and Stochastic Dynamics
- _id: 34dbf174-11ca-11ed-8bc3-afe9d43d4b9c
  grant_number: E208
  name: Configuration Spaces over Non-Smooth Spaces
- _id: 34c6ea2d-11ca-11ed-8bc3-c04f3c502833
  grant_number: ESP156_N
  name: Gradient flow techniques for quantum Markov semigroups
publication: Journal of Evolution Equations
publication_identifier:
  eissn:
  - 1424-3202
  issn:
  - 1424-3199
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Ergodic decompositions of Dirichlet forms under order isomorphisms
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 23
year: '2023'
...
