---
_id: '184'
abstract:
- lang: eng
text: We prove that for every d ≥ 2, deciding if a pure, d-dimensional, simplicial
complex is shellable is NP-hard, hence NP-complete. This resolves a question raised,
e.g., by Danaraj and Klee in 1978. Our reduction also yields that for every d
≥ 2 and k ≥ 0, deciding if a pure, d-dimensional, simplicial complex is k-decomposable
is NP-hard. For d ≥ 3, both problems remain NP-hard when restricted to contractible
pure d-dimensional complexes.
acknowledgement: 'Partially supported by the project EMBEDS II (CZ: 7AMB17FR029, FR:
38087RM) of Czech-French collaboration.'
alternative_title:
- Leibniz International Proceedings in Information, LIPIcs
author:
- first_name: Xavier
full_name: Goaoc, Xavier
last_name: Goaoc
- first_name: Pavel
full_name: Paták, Pavel
last_name: Paták
- first_name: Zuzana
full_name: Patakova, Zuzana
id: 48B57058-F248-11E8-B48F-1D18A9856A87
last_name: Patakova
orcid: 0000-0002-3975-1683
- first_name: Martin
full_name: Tancer, Martin
id: 38AC689C-F248-11E8-B48F-1D18A9856A87
last_name: Tancer
orcid: 0000-0002-1191-6714
- first_name: Uli
full_name: Wagner, Uli
id: 36690CA2-F248-11E8-B48F-1D18A9856A87
last_name: Wagner
orcid: 0000-0002-1494-0568
citation:
ama: 'Goaoc X, Paták P, Patakova Z, Tancer M, Wagner U. Shellability is NP-complete.
In: Vol 99. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2018:41:1-41:16.
doi:10.4230/LIPIcs.SoCG.2018.41'
apa: 'Goaoc, X., Paták, P., Patakova, Z., Tancer, M., & Wagner, U. (2018). Shellability
is NP-complete (Vol. 99, p. 41:1-41:16). Presented at the SoCG: Symposium on Computational
Geometry, Budapest, Hungary: Schloss Dagstuhl - Leibniz-Zentrum für Informatik.
https://doi.org/10.4230/LIPIcs.SoCG.2018.41'
chicago: Goaoc, Xavier, Pavel Paták, Zuzana Patakova, Martin Tancer, and Uli Wagner.
“Shellability Is NP-Complete,” 99:41:1-41:16. Schloss Dagstuhl - Leibniz-Zentrum
für Informatik, 2018. https://doi.org/10.4230/LIPIcs.SoCG.2018.41.
ieee: 'X. Goaoc, P. Paták, Z. Patakova, M. Tancer, and U. Wagner, “Shellability
is NP-complete,” presented at the SoCG: Symposium on Computational Geometry, Budapest,
Hungary, 2018, vol. 99, p. 41:1-41:16.'
ista: 'Goaoc X, Paták P, Patakova Z, Tancer M, Wagner U. 2018. Shellability is NP-complete.
SoCG: Symposium on Computational Geometry, Leibniz International Proceedings in
Information, LIPIcs, vol. 99, 41:1-41:16.'
mla: Goaoc, Xavier, et al. Shellability Is NP-Complete. Vol. 99, Schloss
Dagstuhl - Leibniz-Zentrum für Informatik, 2018, p. 41:1-41:16, doi:10.4230/LIPIcs.SoCG.2018.41.
short: X. Goaoc, P. Paták, Z. Patakova, M. Tancer, U. Wagner, in:, Schloss Dagstuhl
- Leibniz-Zentrum für Informatik, 2018, p. 41:1-41:16.
conference:
end_date: 2018-06-14
location: Budapest, Hungary
name: 'SoCG: Symposium on Computational Geometry'
start_date: 2018-06-11
date_created: 2018-12-11T11:45:04Z
date_published: 2018-06-11T00:00:00Z
date_updated: 2025-06-04T07:49:02Z
day: '11'
ddc:
- '516'
- '000'
department:
- _id: UlWa
doi: 10.4230/LIPIcs.SoCG.2018.41
file:
- access_level: open_access
checksum: d12bdd60f04a57307867704b5f930afd
content_type: application/pdf
creator: dernst
date_created: 2018-12-17T16:35:02Z
date_updated: 2020-07-14T12:45:18Z
file_id: '5725'
file_name: 2018_LIPIcs_Goaoc.pdf
file_size: 718414
relation: main_file
file_date_updated: 2020-07-14T12:45:18Z
has_accepted_license: '1'
intvolume: ' 99'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 41:1 - 41:16
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '7736'
quality_controlled: '1'
related_material:
record:
- id: '7108'
relation: later_version
status: public
scopus_import: 1
status: public
title: Shellability is NP-complete
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 99
year: '2018'
...
---
_id: '185'
abstract:
- lang: eng
text: We resolve in the affirmative conjectures of A. Skopenkov and Repovš (1998),
and M. Skopenkov (2003) generalizing the classical Hanani-Tutte theorem to the
setting of approximating maps of graphs on 2-dimensional surfaces by embeddings.
Our proof of this result is constructive and almost immediately implies an efficient
algorithm for testing whether a given piecewise linear map of a graph in a surface
is approximable by an embedding. More precisely, an instance of this problem consists
of (i) a graph G whose vertices are partitioned into clusters and whose inter-cluster
edges are partitioned into bundles, and (ii) a region R of a 2-dimensional compact
surface M given as the union of a set of pairwise disjoint discs corresponding
to the clusters and a set of pairwise disjoint "pipes" corresponding
to the bundles, connecting certain pairs of these discs. We are to decide whether
G can be embedded inside M so that the vertices in every cluster are drawn in
the corresponding disc, the edges in every bundle pass only through its corresponding
pipe, and every edge crosses the boundary of each disc at most once.
alternative_title:
- Leibniz International Proceedings in Information, LIPIcs
article_number: '39'
author:
- first_name: Radoslav
full_name: Fulek, Radoslav
id: 39F3FFE4-F248-11E8-B48F-1D18A9856A87
last_name: Fulek
orcid: 0000-0001-8485-1774
- first_name: Jan
full_name: Kynčl, Jan
last_name: Kynčl
citation:
ama: 'Fulek R, Kynčl J. Hanani-Tutte for approximating maps of graphs. In: Vol 99.
Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2018. doi:10.4230/LIPIcs.SoCG.2018.39'
apa: 'Fulek, R., & Kynčl, J. (2018). Hanani-Tutte for approximating maps of
graphs (Vol. 99). Presented at the SoCG: Symposium on Computational Geometry,
Budapest, Hungary: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. https://doi.org/10.4230/LIPIcs.SoCG.2018.39'
chicago: Fulek, Radoslav, and Jan Kynčl. “Hanani-Tutte for Approximating Maps of
Graphs,” Vol. 99. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2018. https://doi.org/10.4230/LIPIcs.SoCG.2018.39.
ieee: 'R. Fulek and J. Kynčl, “Hanani-Tutte for approximating maps of graphs,” presented
at the SoCG: Symposium on Computational Geometry, Budapest, Hungary, 2018, vol.
99.'
ista: 'Fulek R, Kynčl J. 2018. Hanani-Tutte for approximating maps of graphs. SoCG:
Symposium on Computational Geometry, Leibniz International Proceedings in Information,
LIPIcs, vol. 99, 39.'
mla: Fulek, Radoslav, and Jan Kynčl. Hanani-Tutte for Approximating Maps of Graphs.
Vol. 99, 39, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2018, doi:10.4230/LIPIcs.SoCG.2018.39.
short: R. Fulek, J. Kynčl, in:, Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
2018.
conference:
end_date: 2018-06-14
location: Budapest, Hungary
name: 'SoCG: Symposium on Computational Geometry'
start_date: 2018-06-11
date_created: 2018-12-11T11:45:04Z
date_published: 2018-01-01T00:00:00Z
date_updated: 2021-01-12T06:53:36Z
day: '01'
ddc:
- '510'
department:
- _id: UlWa
doi: 10.4230/LIPIcs.SoCG.2018.39
file:
- access_level: open_access
checksum: f1b94f1a75b37c414a1f61d59fb2cd4c
content_type: application/pdf
creator: dernst
date_created: 2018-12-17T12:33:52Z
date_updated: 2020-07-14T12:45:19Z
file_id: '5701'
file_name: 2018_LIPIcs_Fulek.pdf
file_size: 718857
relation: main_file
file_date_updated: 2020-07-14T12:45:19Z
has_accepted_license: '1'
intvolume: ' 99'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
project:
- _id: 261FA626-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: M02281
name: Eliminating intersections in drawings of graphs
publication_identifier:
isbn:
- 978-3-95977-066-8
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '7735'
quality_controlled: '1'
scopus_import: 1
status: public
title: Hanani-Tutte for approximating maps of graphs
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 99
year: '2018'
...
---
_id: '186'
abstract:
- lang: eng
text: 'A drawing of a graph on a surface is independently even if every pair of
nonadjacent edges in the drawing crosses an even number of times. The ℤ2-genus
of a graph G is the minimum g such that G has an independently even drawing on
the orientable surface of genus g. An unpublished result by Robertson and Seymour
implies that for every t, every graph of sufficiently large genus contains as
a minor a projective t × t grid or one of the following so-called t-Kuratowski
graphs: K3, t, or t copies of K5 or K3,3 sharing at most 2 common vertices. We
show that the ℤ2-genus of graphs in these families is unbounded in t; in fact,
equal to their genus. Together, this implies that the genus of a graph is bounded
from above by a function of its ℤ2-genus, solving a problem posed by Schaefer
and Štefankovič, and giving an approximate version of the Hanani-Tutte theorem
on orientable surfaces.'
alternative_title:
- LIPIcs
article_processing_charge: No
arxiv: 1
author:
- first_name: Radoslav
full_name: Fulek, Radoslav
id: 39F3FFE4-F248-11E8-B48F-1D18A9856A87
last_name: Fulek
orcid: 0000-0001-8485-1774
- first_name: Jan
full_name: Kynčl, Jan
last_name: Kynčl
citation:
ama: 'Fulek R, Kynčl J. The ℤ2-Genus of Kuratowski minors. In: Vol 99. Schloss Dagstuhl
- Leibniz-Zentrum für Informatik; 2018:40.1-40.14. doi:10.4230/LIPIcs.SoCG.2018.40'
apa: 'Fulek, R., & Kynčl, J. (2018). The ℤ2-Genus of Kuratowski minors (Vol.
99, p. 40.1-40.14). Presented at the SoCG: Symposium on Computational Geometry,
Budapest, Hungary: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. https://doi.org/10.4230/LIPIcs.SoCG.2018.40'
chicago: Fulek, Radoslav, and Jan Kynčl. “The ℤ2-Genus of Kuratowski Minors,” 99:40.1-40.14.
Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2018. https://doi.org/10.4230/LIPIcs.SoCG.2018.40.
ieee: 'R. Fulek and J. Kynčl, “The ℤ2-Genus of Kuratowski minors,” presented at
the SoCG: Symposium on Computational Geometry, Budapest, Hungary, 2018, vol. 99,
p. 40.1-40.14.'
ista: 'Fulek R, Kynčl J. 2018. The ℤ2-Genus of Kuratowski minors. SoCG: Symposium
on Computational Geometry, LIPIcs, vol. 99, 40.1-40.14.'
mla: Fulek, Radoslav, and Jan Kynčl. The ℤ2-Genus of Kuratowski Minors. Vol.
99, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2018, p. 40.1-40.14, doi:10.4230/LIPIcs.SoCG.2018.40.
short: R. Fulek, J. Kynčl, in:, Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
2018, p. 40.1-40.14.
conference:
end_date: 2018-06-14
location: Budapest, Hungary
name: 'SoCG: Symposium on Computational Geometry'
start_date: 2018-06-11
date_created: 2018-12-11T11:45:05Z
date_published: 2018-06-11T00:00:00Z
date_updated: 2025-04-14T13:52:37Z
day: '11'
department:
- _id: UlWa
doi: 10.4230/LIPIcs.SoCG.2018.40
external_id:
arxiv:
- '1803.05085'
intvolume: ' 99'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1803.05085
month: '06'
oa: 1
oa_version: Submitted Version
page: 40.1 - 40.14
project:
- _id: 261FA626-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: M02281
name: Eliminating intersections in drawings of graphs
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '7734'
quality_controlled: '1'
related_material:
record:
- id: '11593'
relation: later_version
status: public
scopus_import: '1'
status: public
title: The ℤ2-Genus of Kuratowski minors
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 99
year: '2018'
...
---
_id: '13'
abstract:
- lang: eng
text: We propose a new method for fabricating digital objects through reusable silicone
molds. Molds are generated by casting liquid silicone into custom 3D printed containers
called metamolds. Metamolds automatically define the cuts that are needed to extract
the cast object from the silicone mold. The shape of metamolds is designed through
a novel segmentation technique, which takes into account both geometric and topological
constraints involved in the process of mold casting. Our technique is simple,
does not require changing the shape or topology of the input objects, and only
requires off-the- shelf materials and technologies. We successfully tested our
method on a set of challenging examples with complex shapes and rich geometric
detail. © 2018 Association for Computing Machinery.
article_number: '136'
article_processing_charge: No
author:
- first_name: Thomas
full_name: Alderighi, Thomas
last_name: Alderighi
- first_name: Luigi
full_name: Malomo, Luigi
last_name: Malomo
- first_name: Daniela
full_name: Giorgi, Daniela
last_name: Giorgi
- first_name: Nico
full_name: Pietroni, Nico
last_name: Pietroni
- first_name: Bernd
full_name: Bickel, Bernd
id: 49876194-F248-11E8-B48F-1D18A9856A87
last_name: Bickel
orcid: 0000-0001-6511-9385
- first_name: Paolo
full_name: Cignoni, Paolo
last_name: Cignoni
citation:
ama: 'Alderighi T, Malomo L, Giorgi D, Pietroni N, Bickel B, Cignoni P. Metamolds:
Computational design of silicone molds. ACM Trans Graph. 2018;37(4). doi:10.1145/3197517.3201381'
apa: 'Alderighi, T., Malomo, L., Giorgi, D., Pietroni, N., Bickel, B., & Cignoni,
P. (2018). Metamolds: Computational design of silicone molds. ACM Trans. Graph.
ACM. https://doi.org/10.1145/3197517.3201381'
chicago: 'Alderighi, Thomas, Luigi Malomo, Daniela Giorgi, Nico Pietroni, Bernd
Bickel, and Paolo Cignoni. “Metamolds: Computational Design of Silicone Molds.”
ACM Trans. Graph. ACM, 2018. https://doi.org/10.1145/3197517.3201381.'
ieee: 'T. Alderighi, L. Malomo, D. Giorgi, N. Pietroni, B. Bickel, and P. Cignoni,
“Metamolds: Computational design of silicone molds,” ACM Trans. Graph.,
vol. 37, no. 4. ACM, 2018.'
ista: 'Alderighi T, Malomo L, Giorgi D, Pietroni N, Bickel B, Cignoni P. 2018. Metamolds:
Computational design of silicone molds. ACM Trans. Graph. 37(4), 136.'
mla: 'Alderighi, Thomas, et al. “Metamolds: Computational Design of Silicone Molds.”
ACM Trans. Graph., vol. 37, no. 4, 136, ACM, 2018, doi:10.1145/3197517.3201381.'
short: T. Alderighi, L. Malomo, D. Giorgi, N. Pietroni, B. Bickel, P. Cignoni, ACM
Trans. Graph. 37 (2018).
date_created: 2018-12-11T11:44:09Z
date_published: 2018-08-04T00:00:00Z
date_updated: 2025-04-14T07:28:57Z
day: '04'
ddc:
- '004'
department:
- _id: BeBi
doi: 10.1145/3197517.3201381
ec_funded: 1
external_id:
isi:
- '000448185000097'
file:
- access_level: open_access
checksum: 61d46273dca4de626accef1d17a0aaad
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:18:52Z
date_updated: 2020-07-14T12:44:43Z
file_id: '5374'
file_name: IST-2018-1038-v1+1_metamolds_authorversion.pdf
file_size: 91939066
relation: main_file
file_date_updated: 2020-07-14T12:44:43Z
has_accepted_license: '1'
intvolume: ' 37'
isi: 1
issue: '4'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Submitted Version
project:
- _id: 24F9549A-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '715767'
name: 'MATERIALIZABLE: Intelligent fabrication-oriented Computational Design and
Modeling'
publication: ACM Trans. Graph.
publication_status: published
publisher: ACM
publist_id: '8043'
pubrep_id: '1038'
quality_controlled: '1'
related_material:
link:
- description: News on IST Homepage
relation: press_release
url: https://ist.ac.at/en/news/metamolds-molding-a-mold/
scopus_import: '1'
status: public
title: 'Metamolds: Computational design of silicone molds'
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 37
year: '2018'
...
---
_id: '13055'
abstract:
- lang: eng
text: "Dataset for manuscript 'Social network plasticity decreases disease transmission
in a eusocial insect'\r\nCompared to previous versions: - raw image files added\r\n
\ - correction of URLs within
README.txt file\r\n"
article_processing_charge: No
author:
- first_name: Nathalie
full_name: Stroeymeyt, Nathalie
last_name: Stroeymeyt
- first_name: Anna V
full_name: Grasse, Anna V
id: 406F989C-F248-11E8-B48F-1D18A9856A87
last_name: Grasse
- first_name: Alessandro
full_name: Crespi, Alessandro
last_name: Crespi
- first_name: Danielle
full_name: Mersch, Danielle
last_name: Mersch
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
- first_name: Laurent
full_name: Keller, Laurent
last_name: Keller
citation:
ama: Stroeymeyt N, Grasse AV, Crespi A, Mersch D, Cremer S, Keller L. Social network
plasticity decreases disease transmission in a eusocial insect. 2018. doi:10.5281/ZENODO.1322669
apa: Stroeymeyt, N., Grasse, A. V., Crespi, A., Mersch, D., Cremer, S., & Keller,
L. (2018). Social network plasticity decreases disease transmission in a eusocial
insect. Zenodo. https://doi.org/10.5281/ZENODO.1322669
chicago: Stroeymeyt, Nathalie, Anna V Grasse, Alessandro Crespi, Danielle Mersch,
Sylvia Cremer, and Laurent Keller. “Social Network Plasticity Decreases Disease
Transmission in a Eusocial Insect.” Zenodo, 2018. https://doi.org/10.5281/ZENODO.1322669.
ieee: N. Stroeymeyt, A. V. Grasse, A. Crespi, D. Mersch, S. Cremer, and L. Keller,
“Social network plasticity decreases disease transmission in a eusocial insect.”
Zenodo, 2018.
ista: Stroeymeyt N, Grasse AV, Crespi A, Mersch D, Cremer S, Keller L. 2018. Social
network plasticity decreases disease transmission in a eusocial insect, Zenodo,
10.5281/ZENODO.1322669.
mla: Stroeymeyt, Nathalie, et al. Social Network Plasticity Decreases Disease
Transmission in a Eusocial Insect. Zenodo, 2018, doi:10.5281/ZENODO.1322669.
short: N. Stroeymeyt, A.V. Grasse, A. Crespi, D. Mersch, S. Cremer, L. Keller, (2018).
date_created: 2023-05-23T13:24:51Z
date_published: 2018-10-23T00:00:00Z
date_updated: 2025-04-15T08:20:52Z
day: '23'
ddc:
- '570'
department:
- _id: SyCr
doi: 10.5281/ZENODO.1322669
main_file_link:
- open_access: '1'
url: https://doi.org/10.5281/zenodo.1480665
month: '10'
oa: 1
oa_version: Published Version
publisher: Zenodo
related_material:
record:
- id: '7'
relation: used_in_publication
status: public
status: public
title: Social network plasticity decreases disease transmission in a eusocial insect
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2018'
...
---
_id: '13059'
abstract:
- lang: eng
text: "This dataset contains a GitHub repository containing all the data, analysis,
Nextflow workflows and Jupyter notebooks to replicate the manuscript titled \"Fast
and accurate large multiple sequence alignments with a root-to-leaf regressive
method\".\r\nIt also contains the Multiple Sequence Alignments (MSAs) generated
and well as the main figures and tables from the manuscript.\r\nThe repository
is also available at GitHub (https://github.com/cbcrg/dpa-analysis) release `v1.2`.\r\nFor
details on how to use the regressive alignment algorithm, see the T-Coffee software
suite (https://github.com/cbcrg/tcoffee)."
article_processing_charge: No
author:
- first_name: Edgar
full_name: Garriga, Edgar
last_name: Garriga
- first_name: Paolo
full_name: di Tommaso, Paolo
last_name: di Tommaso
- first_name: Cedrik
full_name: Magis, Cedrik
last_name: Magis
- first_name: Ionas
full_name: Erb, Ionas
last_name: Erb
- first_name: Leila
full_name: Mansouri, Leila
last_name: Mansouri
- first_name: Athanasios
full_name: Baltzis, Athanasios
last_name: Baltzis
- first_name: Hafid
full_name: Laayouni, Hafid
last_name: Laayouni
- first_name: Fyodor
full_name: Kondrashov, Fyodor
id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
last_name: Kondrashov
orcid: 0000-0001-8243-4694
- first_name: Evan
full_name: Floden, Evan
last_name: Floden
- first_name: Cedric
full_name: Notredame, Cedric
last_name: Notredame
citation:
ama: Garriga E, di Tommaso P, Magis C, et al. Fast and accurate large multiple sequence
alignments with a root-to-leaf regressive method. 2018. doi:10.5281/ZENODO.2025846
apa: Garriga, E., di Tommaso, P., Magis, C., Erb, I., Mansouri, L., Baltzis, A.,
… Notredame, C. (2018). Fast and accurate large multiple sequence alignments with
a root-to-leaf regressive method. Zenodo. https://doi.org/10.5281/ZENODO.2025846
chicago: Garriga, Edgar, Paolo di Tommaso, Cedrik Magis, Ionas Erb, Leila Mansouri,
Athanasios Baltzis, Hafid Laayouni, Fyodor Kondrashov, Evan Floden, and Cedric
Notredame. “Fast and Accurate Large Multiple Sequence Alignments with a Root-to-Leaf
Regressive Method.” Zenodo, 2018. https://doi.org/10.5281/ZENODO.2025846.
ieee: E. Garriga et al., “Fast and accurate large multiple sequence alignments
with a root-to-leaf regressive method.” Zenodo, 2018.
ista: Garriga E, di Tommaso P, Magis C, Erb I, Mansouri L, Baltzis A, Laayouni H,
Kondrashov F, Floden E, Notredame C. 2018. Fast and accurate large multiple sequence
alignments with a root-to-leaf regressive method, Zenodo, 10.5281/ZENODO.2025846.
mla: Garriga, Edgar, et al. Fast and Accurate Large Multiple Sequence Alignments
with a Root-to-Leaf Regressive Method. Zenodo, 2018, doi:10.5281/ZENODO.2025846.
short: E. Garriga, P. di Tommaso, C. Magis, I. Erb, L. Mansouri, A. Baltzis, H.
Laayouni, F. Kondrashov, E. Floden, C. Notredame, (2018).
date_created: 2023-05-23T16:08:20Z
date_published: 2018-12-07T00:00:00Z
date_updated: 2025-07-10T11:54:19Z
day: '07'
ddc:
- '570'
department:
- _id: FyKo
doi: 10.5281/ZENODO.2025846
main_file_link:
- open_access: '1'
url: https://doi.org/10.5281/zenodo.3271452
month: '12'
oa: 1
oa_version: Published Version
publisher: Zenodo
related_material:
record:
- id: '7181'
relation: used_in_publication
status: public
status: public
title: Fast and accurate large multiple sequence alignments with a root-to-leaf regressive
method
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2018'
...
---
_id: '131'
abstract:
- lang: eng
text: 'XY systems usually show chromosome-wide compensation of X-linked genes, while
in many ZW systems, compensation is restricted to a minority of dosage-sensitive
genes. Why such differences arose is still unclear. Here, we combine comparative
genomics, transcriptomics and proteomics to obtain a complete overview of the
evolution of gene dosage on the Z-chromosome of Schistosoma parasites. We compare
the Z-chromosome gene content of African (Schistosoma mansoni and S. haematobium)
and Asian (S. japonicum) schistosomes and describe lineage-specific evolutionary
strata. We use these to assess gene expression evolution following sex-linkage.
The resulting patterns suggest a reduction in expression of Z-linked genes in
females, combined with upregulation of the Z in both sexes, in line with the first
step of Ohno’s classic model of dosage compensation evolution. Quantitative proteomics
suggest that post-transcriptional mechanisms do not play a major role in balancing
the expression of Z-linked genes. '
acknowledgement: We are grateful to Lu Dabing (Soochow University, Suzhou, China)
for providing Schistosoma japonicum samples, to Ariana Macon (IST Austria) and Georgette
Stovall (JLU Giessen) for technical assistance, to IT support at IST Austria for
providing optimal environment to bioinformatic analyses, and to the Vicoso lab for
comments on the manuscript.
article_number: e35684
article_processing_charge: No
article_type: original
author:
- first_name: Marion A
full_name: Picard, Marion A
id: 2C921A7A-F248-11E8-B48F-1D18A9856A87
last_name: Picard
orcid: 0000-0002-8101-2518
- first_name: Celine
full_name: Cosseau, Celine
last_name: Cosseau
- first_name: Sabrina
full_name: Ferré, Sabrina
last_name: Ferré
- first_name: Thomas
full_name: Quack, Thomas
last_name: Quack
- first_name: Christoph
full_name: Grevelding, Christoph
last_name: Grevelding
- first_name: Yohann
full_name: Couté, Yohann
last_name: Couté
- first_name: Beatriz
full_name: Vicoso, Beatriz
id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
last_name: Vicoso
orcid: 0000-0002-4579-8306
citation:
ama: Picard MAL, Cosseau C, Ferré S, et al. Evolution of gene dosage on the Z-chromosome
of schistosome parasites. eLife. 2018;7. doi:10.7554/eLife.35684
apa: Picard, M. A. L., Cosseau, C., Ferré, S., Quack, T., Grevelding, C., Couté,
Y., & Vicoso, B. (2018). Evolution of gene dosage on the Z-chromosome of schistosome
parasites. ELife. eLife Sciences Publications. https://doi.org/10.7554/eLife.35684
chicago: Picard, Marion A L, Celine Cosseau, Sabrina Ferré, Thomas Quack, Christoph
Grevelding, Yohann Couté, and Beatriz Vicoso. “Evolution of Gene Dosage on the
Z-Chromosome of Schistosome Parasites.” ELife. eLife Sciences Publications,
2018. https://doi.org/10.7554/eLife.35684.
ieee: M. A. L. Picard et al., “Evolution of gene dosage on the Z-chromosome
of schistosome parasites,” eLife, vol. 7. eLife Sciences Publications,
2018.
ista: Picard MAL, Cosseau C, Ferré S, Quack T, Grevelding C, Couté Y, Vicoso B.
2018. Evolution of gene dosage on the Z-chromosome of schistosome parasites. eLife.
7, e35684.
mla: Picard, Marion A. L., et al. “Evolution of Gene Dosage on the Z-Chromosome
of Schistosome Parasites.” ELife, vol. 7, e35684, eLife Sciences Publications,
2018, doi:10.7554/eLife.35684.
short: M.A.L. Picard, C. Cosseau, S. Ferré, T. Quack, C. Grevelding, Y. Couté, B.
Vicoso, ELife 7 (2018).
date_created: 2018-12-11T11:44:47Z
date_published: 2018-08-13T00:00:00Z
date_updated: 2025-04-15T08:18:37Z
day: '13'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.7554/eLife.35684
external_id:
isi:
- '000441388200001'
file:
- access_level: open_access
checksum: d6331d4385b1fffd6b47b45d5949d841
content_type: application/pdf
creator: dernst
date_created: 2018-12-17T11:55:05Z
date_updated: 2020-07-14T12:44:43Z
file_id: '5695'
file_name: 2018_eLife_Picard.pdf
file_size: 3158125
relation: main_file
file_date_updated: 2020-07-14T12:44:43Z
has_accepted_license: '1'
intvolume: ' 7'
isi: 1
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
project:
- _id: 250ED89C-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P28842-B22
name: Sex chromosome evolution under male- and female- heterogamety
publication: eLife
publication_status: published
publisher: eLife Sciences Publications
publist_id: '7792'
quality_controlled: '1'
related_material:
record:
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relation: popular_science
status: public
scopus_import: '1'
status: public
title: Evolution of gene dosage on the Z-chromosome of schistosome parasites
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 7
year: '2018'
...
---
_id: '132'
abstract:
- lang: eng
text: Pancreas development involves a coordinated process in which an early phase
of cell segregation is followed by a longer phase of lineage restriction, expansion,
and tissue remodeling. By combining clonal tracing and whole-mount reconstruction
with proliferation kinetics and single-cell transcriptional profiling, we define
the functional basis of pancreas morphogenesis. We show that the large-scale organization
of mouse pancreas can be traced to the activity of self-renewing precursors positioned
at the termini of growing ducts, which act collectively to drive serial rounds
of stochastic ductal bifurcation balanced by termination. During this phase of
branching morphogenesis, multipotent precursors become progressively fate-restricted,
giving rise to self-renewing acinar-committed precursors that are conveyed with
growing ducts, as well as ductal progenitors that expand the trailing ducts and
give rise to delaminating endocrine cells. These findings define quantitatively
how the functional behavior and lineage progression of precursor pools determine
the large-scale patterning of pancreatic sub-compartments.
acknowledgement: E.H. is funded by a Junior Research Fellowship from Trinity College,
Cam-bridge, a Sir Henry Wellcome Fellowship from the Wellcome Trust, and theBettencourt-Schueller
Young Researcher Prize for support.
article_processing_charge: No
article_type: original
author:
- first_name: Magdalena
full_name: Sznurkowska, Magdalena
last_name: Sznurkowska
- first_name: Edouard B
full_name: Hannezo, Edouard B
id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
last_name: Hannezo
orcid: 0000-0001-6005-1561
- first_name: Roberta
full_name: Azzarelli, Roberta
last_name: Azzarelli
- first_name: Steffen
full_name: Rulands, Steffen
last_name: Rulands
- first_name: Sonia
full_name: Nestorowa, Sonia
last_name: Nestorowa
- first_name: Christopher
full_name: Hindley, Christopher
last_name: Hindley
- first_name: Jennifer
full_name: Nichols, Jennifer
last_name: Nichols
- first_name: Berthold
full_name: Göttgens, Berthold
last_name: Göttgens
- first_name: Meritxell
full_name: Huch, Meritxell
last_name: Huch
- first_name: Anna
full_name: Philpott, Anna
last_name: Philpott
- first_name: Benjamin
full_name: Simons, Benjamin
last_name: Simons
citation:
ama: Sznurkowska M, Hannezo EB, Azzarelli R, et al. Defining lineage potential and
fate behavior of precursors during pancreas development. Developmental Cell.
2018;46(3):360-375. doi:10.1016/j.devcel.2018.06.028
apa: Sznurkowska, M., Hannezo, E. B., Azzarelli, R., Rulands, S., Nestorowa, S.,
Hindley, C., … Simons, B. (2018). Defining lineage potential and fate behavior
of precursors during pancreas development. Developmental Cell. Cell Press.
https://doi.org/10.1016/j.devcel.2018.06.028
chicago: Sznurkowska, Magdalena, Edouard B Hannezo, Roberta Azzarelli, Steffen Rulands,
Sonia Nestorowa, Christopher Hindley, Jennifer Nichols, et al. “Defining Lineage
Potential and Fate Behavior of Precursors during Pancreas Development.” Developmental
Cell. Cell Press, 2018. https://doi.org/10.1016/j.devcel.2018.06.028.
ieee: M. Sznurkowska et al., “Defining lineage potential and fate behavior
of precursors during pancreas development,” Developmental Cell, vol. 46,
no. 3. Cell Press, pp. 360–375, 2018.
ista: Sznurkowska M, Hannezo EB, Azzarelli R, Rulands S, Nestorowa S, Hindley C,
Nichols J, Göttgens B, Huch M, Philpott A, Simons B. 2018. Defining lineage potential
and fate behavior of precursors during pancreas development. Developmental Cell.
46(3), 360–375.
mla: Sznurkowska, Magdalena, et al. “Defining Lineage Potential and Fate Behavior
of Precursors during Pancreas Development.” Developmental Cell, vol. 46,
no. 3, Cell Press, 2018, pp. 360–75, doi:10.1016/j.devcel.2018.06.028.
short: M. Sznurkowska, E.B. Hannezo, R. Azzarelli, S. Rulands, S. Nestorowa, C.
Hindley, J. Nichols, B. Göttgens, M. Huch, A. Philpott, B. Simons, Developmental
Cell 46 (2018) 360–375.
date_created: 2018-12-11T11:44:48Z
date_published: 2018-08-06T00:00:00Z
date_updated: 2023-09-11T12:52:41Z
day: '06'
ddc:
- '570'
department:
- _id: EdHa
doi: 10.1016/j.devcel.2018.06.028
external_id:
isi:
- '000441327300012'
file:
- access_level: open_access
checksum: 78d2062b9e3c3b90fe71545aeb6d2f65
content_type: application/pdf
creator: dernst
date_created: 2018-12-17T10:49:49Z
date_updated: 2020-07-14T12:44:43Z
file_id: '5694'
file_name: 2018_DevelopmentalCell_Sznurkowska.pdf
file_size: 8948384
relation: main_file
file_date_updated: 2020-07-14T12:44:43Z
has_accepted_license: '1'
intvolume: ' 46'
isi: 1
issue: '3'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 360 - 375
publication: Developmental Cell
publication_status: published
publisher: Cell Press
publist_id: '7791'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Defining lineage potential and fate behavior of precursors during pancreas
development
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 46
year: '2018'
...
---
_id: '198'
abstract:
- lang: eng
text: We consider a class of students learning a language from a teacher. The situation
can be interpreted as a group of child learners receiving input from the linguistic
environment. The teacher provides sample sentences. The students try to learn
the grammar from the teacher. In addition to just listening to the teacher, the
students can also communicate with each other. The students hold hypotheses about
the grammar and change them if they receive counter evidence. The process stops
when all students have converged to the correct grammar. We study how the time
to convergence depends on the structure of the classroom by introducing and evaluating
various complexity measures. We find that structured communication between students,
although potentially introducing confusion, can greatly reduce some of the complexity
measures. Our theory can also be interpreted as applying to the scientific process,
where nature is the teacher and the scientists are the students.
article_number: '20180073'
article_processing_charge: No
article_type: original
author:
- first_name: Rasmus
full_name: Ibsen-Jensen, Rasmus
id: 3B699956-F248-11E8-B48F-1D18A9856A87
last_name: Ibsen-Jensen
orcid: 0000-0003-4783-0389
- first_name: Josef
full_name: Tkadlec, Josef
id: 3F24CCC8-F248-11E8-B48F-1D18A9856A87
last_name: Tkadlec
orcid: 0000-0002-1097-9684
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Martin
full_name: Nowak, Martin
last_name: Nowak
citation:
ama: Ibsen-Jensen R, Tkadlec J, Chatterjee K, Nowak M. Language acquisition with
communication between learners. Journal of the Royal Society Interface.
2018;15(140). doi:10.1098/rsif.2018.0073
apa: Ibsen-Jensen, R., Tkadlec, J., Chatterjee, K., & Nowak, M. (2018). Language
acquisition with communication between learners. Journal of the Royal Society
Interface. The Royal Society. https://doi.org/10.1098/rsif.2018.0073
chicago: Ibsen-Jensen, Rasmus, Josef Tkadlec, Krishnendu Chatterjee, and Martin
Nowak. “Language Acquisition with Communication between Learners.” Journal
of the Royal Society Interface. The Royal Society, 2018. https://doi.org/10.1098/rsif.2018.0073.
ieee: R. Ibsen-Jensen, J. Tkadlec, K. Chatterjee, and M. Nowak, “Language acquisition
with communication between learners,” Journal of the Royal Society Interface,
vol. 15, no. 140. The Royal Society, 2018.
ista: Ibsen-Jensen R, Tkadlec J, Chatterjee K, Nowak M. 2018. Language acquisition
with communication between learners. Journal of the Royal Society Interface. 15(140),
20180073.
mla: Ibsen-Jensen, Rasmus, et al. “Language Acquisition with Communication between
Learners.” Journal of the Royal Society Interface, vol. 15, no. 140, 20180073,
The Royal Society, 2018, doi:10.1098/rsif.2018.0073.
short: R. Ibsen-Jensen, J. Tkadlec, K. Chatterjee, M. Nowak, Journal of the Royal
Society Interface 15 (2018).
date_created: 2018-12-11T11:45:09Z
date_published: 2018-03-01T00:00:00Z
date_updated: 2025-04-15T07:26:26Z
day: '01'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1098/rsif.2018.0073
ec_funded: 1
external_id:
isi:
- '000428576200023'
pmid:
- '29593089'
file:
- access_level: open_access
checksum: 444e1a9d98eb0e780671be82b13025f3
content_type: application/pdf
creator: dernst
date_created: 2019-02-12T07:54:37Z
date_updated: 2020-07-14T12:45:22Z
file_id: '5955'
file_name: 2018_RS_IbsenJensen.pdf
file_size: 219837
relation: main_file
file_date_updated: 2020-07-14T12:45:22Z
has_accepted_license: '1'
intvolume: ' 15'
isi: 1
issue: '140'
language:
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month: '03'
oa: 1
oa_version: Submitted Version
pmid: 1
project:
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
publication: Journal of the Royal Society Interface
publication_identifier:
eissn:
- 1742-5662
publication_status: published
publisher: The Royal Society
publist_id: '7715'
quality_controlled: '1'
related_material:
link:
- relation: supplementary_material
url: https://dx.doi.org/10.6084/m9.figshare.c.4028971
record:
- id: '9814'
relation: research_data
status: public
scopus_import: '1'
status: public
title: Language acquisition with communication between learners
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 15
year: '2018'
...
---
_id: '199'
abstract:
- lang: eng
text: Sex-biased genes are central to the study of sexual selection, sexual antagonism,
and sex chromosome evolution. We describe a comprehensive de novo assembled transcriptome
in the common frog Rana temporaria based on five developmental stages and three
adult tissues from both sexes, obtained from a population with karyotypically
homomorphic but genetically differentiated sex chromosomes. This allows the study
of sex-biased gene expression throughout development, and its effect on the rate
of gene evolution while accounting for pleiotropic expression, which is known
to negatively correlate with the evolutionary rate. Overall, sex-biased genes
had little overlap among developmental stages and adult tissues. Late developmental
stages and gonad tissues had the highest numbers of stage-or tissue-specific genes.
We find that pleiotropic gene expression is a better predictor than sex bias for
the evolutionary rate of genes, though it often interacts with sex bias. Although
genetically differentiated, the sex chromosomes were not enriched in sex-biased
genes, possibly due to a very recent arrest of XY recombination. These results
extend our understanding of the developmental dynamics, tissue specificity, and
genomic localization of sex-biased genes.
article_number: '294'
article_processing_charge: No
author:
- first_name: Wen
full_name: Ma, Wen
last_name: Ma
- first_name: Paris
full_name: Veltsos, Paris
last_name: Veltsos
- first_name: Melissa A
full_name: Toups, Melissa A
id: 4E099E4E-F248-11E8-B48F-1D18A9856A87
last_name: Toups
orcid: 0000-0002-9752-7380
- first_name: Nicolas
full_name: Rodrigues, Nicolas
last_name: Rodrigues
- first_name: Roberto
full_name: Sermier, Roberto
last_name: Sermier
- first_name: Daniel
full_name: Jeffries, Daniel
last_name: Jeffries
- first_name: Nicolas
full_name: Perrin, Nicolas
last_name: Perrin
citation:
ama: Ma W, Veltsos P, Toups MA, et al. Tissue specificity and dynamics of sex biased
gene expression in a common frog population with differentiated, yet homomorphic,
sex chromosomes. Genes. 2018;9(6). doi:10.3390/genes9060294
apa: Ma, W., Veltsos, P., Toups, M. A., Rodrigues, N., Sermier, R., Jeffries, D.,
& Perrin, N. (2018). Tissue specificity and dynamics of sex biased gene expression
in a common frog population with differentiated, yet homomorphic, sex chromosomes.
Genes. MDPI. https://doi.org/10.3390/genes9060294
chicago: Ma, Wen, Paris Veltsos, Melissa A Toups, Nicolas Rodrigues, Roberto Sermier,
Daniel Jeffries, and Nicolas Perrin. “Tissue Specificity and Dynamics of Sex Biased
Gene Expression in a Common Frog Population with Differentiated, yet Homomorphic,
Sex Chromosomes.” Genes. MDPI, 2018. https://doi.org/10.3390/genes9060294.
ieee: W. Ma et al., “Tissue specificity and dynamics of sex biased gene expression
in a common frog population with differentiated, yet homomorphic, sex chromosomes,”
Genes, vol. 9, no. 6. MDPI, 2018.
ista: Ma W, Veltsos P, Toups MA, Rodrigues N, Sermier R, Jeffries D, Perrin N. 2018.
Tissue specificity and dynamics of sex biased gene expression in a common frog
population with differentiated, yet homomorphic, sex chromosomes. Genes. 9(6),
294.
mla: Ma, Wen, et al. “Tissue Specificity and Dynamics of Sex Biased Gene Expression
in a Common Frog Population with Differentiated, yet Homomorphic, Sex Chromosomes.”
Genes, vol. 9, no. 6, 294, MDPI, 2018, doi:10.3390/genes9060294.
short: W. Ma, P. Veltsos, M.A. Toups, N. Rodrigues, R. Sermier, D. Jeffries, N.
Perrin, Genes 9 (2018).
date_created: 2018-12-11T11:45:09Z
date_published: 2018-06-12T00:00:00Z
date_updated: 2024-12-11T13:13:35Z
day: '12'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.3390/genes9060294
external_id:
isi:
- '000436494200026'
file:
- access_level: open_access
checksum: 423069beb1cd3cdd25bf3f464b38f1d7
content_type: application/pdf
creator: dernst
date_created: 2019-02-01T07:52:28Z
date_updated: 2020-07-14T12:45:22Z
file_id: '5905'
file_name: 2018_Genes_Ma.pdf
file_size: 3985796
relation: main_file
file_date_updated: 2020-07-14T12:45:22Z
has_accepted_license: '1'
intvolume: ' 9'
isi: 1
issue: '6'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
publication: Genes
publication_status: published
publisher: MDPI
publist_id: '7714'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Tissue specificity and dynamics of sex biased gene expression in a common frog
population with differentiated, yet homomorphic, sex chromosomes
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2018'
...
---
_id: '20'
abstract:
- lang: eng
text: 'Background: Norepinephrine (NE) signaling has a key role in white adipose
tissue (WAT) functions, including lipolysis, free fatty acid liberation and, under
certain conditions, conversion of white into brite (brown-in-white) adipocytes.
However, acute effects of NE stimulation have not been described at the transcriptional
network level. Results: We used RNA-seq to uncover a broad transcriptional response.
The inference of protein-protein and protein-DNA interaction networks allowed
us to identify a set of immediate-early genes (IEGs) with high betweenness, validating
our approach and suggesting a hierarchical control of transcriptional regulation.
In addition, we identified a transcriptional regulatory network with IEGs as master
regulators, including HSF1 and NFIL3 as novel NE-induced IEG candidates. Moreover,
a functional enrichment analysis and gene clustering into functional modules suggest
a crosstalk between metabolic, signaling, and immune responses. Conclusions: Altogether,
our network biology approach explores for the first time the immediate-early systems
level response of human adipocytes to acute sympathetic activation, thereby providing
a first network basis of early cell fate programs and crosstalks between metabolic
and transcriptional networks required for proper WAT function.'
acknowledgement: This work was funded by the German Centre for Diabetes Research (DZD)
and the Austrian Science Fund (FWF, P25729-B19).
article_processing_charge: No
article_type: original
author:
- first_name: Juan
full_name: Higareda Almaraz, Juan
last_name: Higareda Almaraz
- first_name: Michael
full_name: Karbiener, Michael
last_name: Karbiener
- first_name: Maude
full_name: Giroud, Maude
last_name: Giroud
- first_name: Florian
full_name: Pauler, Florian
id: 48EA0138-F248-11E8-B48F-1D18A9856A87
last_name: Pauler
orcid: 0000-0002-7462-0048
- first_name: Teresa
full_name: Gerhalter, Teresa
last_name: Gerhalter
- first_name: Stephan
full_name: Herzig, Stephan
last_name: Herzig
- first_name: Marcel
full_name: Scheideler, Marcel
last_name: Scheideler
citation:
ama: Higareda Almaraz J, Karbiener M, Giroud M, et al. Norepinephrine triggers an
immediate-early regulatory network response in primary human white adipocytes.
BMC Genomics. 2018;19(1). doi:10.1186/s12864-018-5173-0
apa: Higareda Almaraz, J., Karbiener, M., Giroud, M., Pauler, F., Gerhalter, T.,
Herzig, S., & Scheideler, M. (2018). Norepinephrine triggers an immediate-early
regulatory network response in primary human white adipocytes. BMC Genomics.
BioMed Central. https://doi.org/10.1186/s12864-018-5173-0
chicago: Higareda Almaraz, Juan, Michael Karbiener, Maude Giroud, Florian Pauler,
Teresa Gerhalter, Stephan Herzig, and Marcel Scheideler. “Norepinephrine Triggers
an Immediate-Early Regulatory Network Response in Primary Human White Adipocytes.”
BMC Genomics. BioMed Central, 2018. https://doi.org/10.1186/s12864-018-5173-0.
ieee: J. Higareda Almaraz et al., “Norepinephrine triggers an immediate-early
regulatory network response in primary human white adipocytes,” BMC Genomics,
vol. 19, no. 1. BioMed Central, 2018.
ista: Higareda Almaraz J, Karbiener M, Giroud M, Pauler F, Gerhalter T, Herzig S,
Scheideler M. 2018. Norepinephrine triggers an immediate-early regulatory network
response in primary human white adipocytes. BMC Genomics. 19(1).
mla: Higareda Almaraz, Juan, et al. “Norepinephrine Triggers an Immediate-Early
Regulatory Network Response in Primary Human White Adipocytes.” BMC Genomics,
vol. 19, no. 1, BioMed Central, 2018, doi:10.1186/s12864-018-5173-0.
short: J. Higareda Almaraz, M. Karbiener, M. Giroud, F. Pauler, T. Gerhalter, S.
Herzig, M. Scheideler, BMC Genomics 19 (2018).
date_created: 2018-12-11T11:44:12Z
date_published: 2018-11-03T00:00:00Z
date_updated: 2023-09-13T09:10:47Z
day: '03'
ddc:
- '570'
department:
- _id: SiHi
doi: 10.1186/s12864-018-5173-0
external_id:
isi:
- '000450976700002'
file:
- access_level: open_access
checksum: a56516e734dab589dc7f3e1915973b4d
content_type: application/pdf
creator: dernst
date_created: 2018-12-17T14:52:57Z
date_updated: 2020-07-14T12:45:23Z
file_id: '5712'
file_name: 2018_BMCGenomics_Higareda.pdf
file_size: 4629784
relation: main_file
file_date_updated: 2020-07-14T12:45:23Z
has_accepted_license: '1'
intvolume: ' 19'
isi: 1
issue: '1'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
publication: BMC Genomics
publication_identifier:
issn:
- 1471-2164
publication_status: published
publisher: BioMed Central
publist_id: '8035'
quality_controlled: '1'
related_material:
record:
- id: '9807'
relation: research_data
status: public
- id: '9808'
relation: research_data
status: public
scopus_import: '1'
status: public
title: Norepinephrine triggers an immediate-early regulatory network response in primary
human white adipocytes
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 19
year: '2018'
...
---
OA_place: repository
OA_type: green
_id: '203'
abstract:
- lang: eng
text: Asymmetric auxin distribution is instrumental for the differential growth
that causes organ bending on tropic stimuli and curvatures during plant development.
Local differences in auxin concentrations are achieved mainly by polarized cellular
distribution of PIN auxin transporters, but whether other mechanisms involving
auxin homeostasis are also relevant for the formation of auxin gradients is not
clear. Here we show that auxin methylation is required for asymmetric auxin distribution
across the hypocotyl, particularly during its response to gravity. We found that
loss-of-function mutants in Arabidopsis IAA CARBOXYL METHYLTRANSFERASE1 (IAMT1)
prematurely unfold the apical hook, and that their hypocotyls are impaired in
gravitropic reorientation. This defect is linked to an auxin-dependent increase
in PIN gene expression, leading to an increased polar auxin transport and lack
of asymmetric distribution of PIN3 in the iamt1 mutant. Gravitropic reorientation
in the iamt1 mutant could be restored with either endodermis-specific expression
of IAMT1 or partial inhibition of polar auxin transport, which also results in
normal PIN gene expression levels. We propose that IAA methylation is necessary
in gravity-sensing cells to restrict polar auxin transport within the range of
auxin levels that allow for differential responses.
article_processing_charge: No
article_type: original
author:
- first_name: Mohamad
full_name: Abbas, Mohamad
id: 47E8FC1C-F248-11E8-B48F-1D18A9856A87
last_name: Abbas
- first_name: García J
full_name: Hernández, García J
last_name: Hernández
- first_name: Stephan
full_name: Pollmann, Stephan
last_name: Pollmann
- first_name: Sophia L
full_name: Samodelov, Sophia L
last_name: Samodelov
- first_name: Martina
full_name: Kolb, Martina
last_name: Kolb
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Ulrich Z
full_name: Hammes, Ulrich Z
last_name: Hammes
- first_name: Matias D
full_name: Zurbriggen, Matias D
last_name: Zurbriggen
- first_name: Miguel
full_name: Blázquez, Miguel
last_name: Blázquez
- first_name: David
full_name: Alabadí, David
last_name: Alabadí
citation:
ama: Abbas M, Hernández GJ, Pollmann S, et al. Auxin methylation is required for
differential growth in Arabidopsis. PNAS. 2018;115(26):6864-6869. doi:10.1073/pnas.1806565115
apa: Abbas, M., Hernández, G. J., Pollmann, S., Samodelov, S. L., Kolb, M., Friml,
J., … Alabadí, D. (2018). Auxin methylation is required for differential growth
in Arabidopsis. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.1806565115
chicago: Abbas, Mohamad, García J Hernández, Stephan Pollmann, Sophia L Samodelov,
Martina Kolb, Jiří Friml, Ulrich Z Hammes, Matias D Zurbriggen, Miguel Blázquez,
and David Alabadí. “Auxin Methylation Is Required for Differential Growth in Arabidopsis.”
PNAS. National Academy of Sciences, 2018. https://doi.org/10.1073/pnas.1806565115.
ieee: M. Abbas et al., “Auxin methylation is required for differential growth
in Arabidopsis,” PNAS, vol. 115, no. 26. National Academy of Sciences,
pp. 6864–6869, 2018.
ista: Abbas M, Hernández GJ, Pollmann S, Samodelov SL, Kolb M, Friml J, Hammes UZ,
Zurbriggen MD, Blázquez M, Alabadí D. 2018. Auxin methylation is required for
differential growth in Arabidopsis. PNAS. 115(26), 6864–6869.
mla: Abbas, Mohamad, et al. “Auxin Methylation Is Required for Differential Growth
in Arabidopsis.” PNAS, vol. 115, no. 26, National Academy of Sciences,
2018, pp. 6864–69, doi:10.1073/pnas.1806565115.
short: M. Abbas, G.J. Hernández, S. Pollmann, S.L. Samodelov, M. Kolb, J. Friml,
U.Z. Hammes, M.D. Zurbriggen, M. Blázquez, D. Alabadí, PNAS 115 (2018) 6864–6869.
date_created: 2018-12-11T11:45:11Z
date_published: 2018-06-26T00:00:00Z
date_updated: 2025-07-10T11:52:05Z
day: '26'
department:
- _id: JiFr
doi: 10.1073/pnas.1806565115
ec_funded: 1
external_id:
isi:
- '000436245000096'
intvolume: ' 115'
isi: 1
issue: '26'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://eprints.nottingham.ac.uk/52388/
month: '06'
oa: 1
oa_version: Submitted Version
page: 6864-6869
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '282300'
name: Polarity and subcellular dynamics in plants
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '7710'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Auxin methylation is required for differential growth in Arabidopsis
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 115
year: '2018'
...
---
_id: '188'
abstract:
- lang: eng
text: Smallest enclosing spheres of finite point sets are central to methods in
topological data analysis. Focusing on Bregman divergences to measure dissimilarity,
we prove bounds on the location of the center of a smallest enclosing sphere.
These bounds depend on the range of radii for which Bregman balls are convex.
acknowledgement: This research is partially supported by the Office of Naval Research,
through grant no. N62909-18-1-2038, and the DFG Collaborative Research Center TRR
109, ‘Discretization in Geometry and Dynamics’, through grant no. I02979-N35 of
the Austrian Science Fund
alternative_title:
- Leibniz International Proceedings in Information, LIPIcs
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Ziga
full_name: Virk, Ziga
last_name: Virk
- first_name: Hubert
full_name: Wagner, Hubert
id: 379CA8B8-F248-11E8-B48F-1D18A9856A87
last_name: Wagner
citation:
ama: 'Edelsbrunner H, Virk Z, Wagner H. Smallest enclosing spheres and Chernoff
points in Bregman geometry. In: Vol 99. Schloss Dagstuhl - Leibniz-Zentrum für
Informatik; 2018:35:1-35:13. doi:10.4230/LIPIcs.SoCG.2018.35'
apa: 'Edelsbrunner, H., Virk, Z., & Wagner, H. (2018). Smallest enclosing spheres
and Chernoff points in Bregman geometry (Vol. 99, p. 35:1-35:13). Presented at
the SoCG: Symposium on Computational Geometry, Budapest, Hungary: Schloss Dagstuhl
- Leibniz-Zentrum für Informatik. https://doi.org/10.4230/LIPIcs.SoCG.2018.35'
chicago: Edelsbrunner, Herbert, Ziga Virk, and Hubert Wagner. “Smallest Enclosing
Spheres and Chernoff Points in Bregman Geometry,” 99:35:1-35:13. Schloss Dagstuhl
- Leibniz-Zentrum für Informatik, 2018. https://doi.org/10.4230/LIPIcs.SoCG.2018.35.
ieee: 'H. Edelsbrunner, Z. Virk, and H. Wagner, “Smallest enclosing spheres and
Chernoff points in Bregman geometry,” presented at the SoCG: Symposium on Computational
Geometry, Budapest, Hungary, 2018, vol. 99, p. 35:1-35:13.'
ista: 'Edelsbrunner H, Virk Z, Wagner H. 2018. Smallest enclosing spheres and Chernoff
points in Bregman geometry. SoCG: Symposium on Computational Geometry, Leibniz
International Proceedings in Information, LIPIcs, vol. 99, 35:1-35:13.'
mla: Edelsbrunner, Herbert, et al. Smallest Enclosing Spheres and Chernoff Points
in Bregman Geometry. Vol. 99, Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
2018, p. 35:1-35:13, doi:10.4230/LIPIcs.SoCG.2018.35.
short: H. Edelsbrunner, Z. Virk, H. Wagner, in:, Schloss Dagstuhl - Leibniz-Zentrum
für Informatik, 2018, p. 35:1-35:13.
conference:
end_date: 2018-06-14
location: Budapest, Hungary
name: 'SoCG: Symposium on Computational Geometry'
start_date: 2018-06-11
date_created: 2018-12-11T11:45:05Z
date_published: 2018-06-11T00:00:00Z
date_updated: 2021-01-12T06:53:48Z
day: '11'
ddc:
- '000'
department:
- _id: HeEd
doi: 10.4230/LIPIcs.SoCG.2018.35
file:
- access_level: open_access
checksum: 7509403803b3ac1aee94bbc2ad293d21
content_type: application/pdf
creator: dernst
date_created: 2018-12-17T16:31:31Z
date_updated: 2020-07-14T12:45:20Z
file_id: '5724'
file_name: 2018_LIPIcs_Edelsbrunner.pdf
file_size: 489080
relation: main_file
file_date_updated: 2020-07-14T12:45:20Z
has_accepted_license: '1'
intvolume: ' 99'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 35:1 - 35:13
project:
- _id: 2561EBF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: I02979-N35
name: Persistence and stability of geometric complexes
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '7733'
quality_controlled: '1'
scopus_import: 1
status: public
title: Smallest enclosing spheres and Chernoff points in Bregman geometry
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 99
year: '2018'
...
---
_id: '19'
abstract:
- lang: eng
text: Bacteria regulate genes to survive antibiotic stress, but regulation can be
far from perfect. When regulation is not optimal, mutations that change gene expression
can contribute to antibiotic resistance. It is not systematically understood to
what extent natural gene regulation is or is not optimal for distinct antibiotics,
and how changes in expression of specific genes quantitatively affect antibiotic
resistance. Here we discover a simple quantitative relation between fitness, gene
expression, and antibiotic potency, which rationalizes our observation that a
multitude of genes and even innate antibiotic defense mechanisms have expression
that is critically nonoptimal under antibiotic treatment. First, we developed
a pooled-strain drug-diffusion assay and screened Escherichia coli overexpression
and knockout libraries, finding that resistance to a range of 31 antibiotics could
result from changing expression of a large and functionally diverse set of genes,
in a primarily but not exclusively drug-specific manner. Second, by synthetically
controlling the expression of single-drug and multidrug resistance genes, we observed
that their fitness-expression functions changed dramatically under antibiotic
treatment in accordance with a log-sensitivity relation. Thus, because many genes
are nonoptimally expressed under antibiotic treatment, many regulatory mutations
can contribute to resistance by altering expression and by activating latent defenses.
article_processing_charge: No
article_type: original
author:
- first_name: Adam
full_name: Palmer, Adam
last_name: Palmer
- first_name: Remy P
full_name: Chait, Remy P
id: 3464AE84-F248-11E8-B48F-1D18A9856A87
last_name: Chait
orcid: 0000-0003-0876-3187
- first_name: Roy
full_name: Kishony, Roy
last_name: Kishony
citation:
ama: Palmer A, Chait RP, Kishony R. Nonoptimal gene expression creates latent potential
for antibiotic resistance. Molecular Biology and Evolution. 2018;35(11):2669-2684.
doi:10.1093/molbev/msy163
apa: Palmer, A., Chait, R. P., & Kishony, R. (2018). Nonoptimal gene expression
creates latent potential for antibiotic resistance. Molecular Biology and Evolution.
Oxford University Press. https://doi.org/10.1093/molbev/msy163
chicago: Palmer, Adam, Remy P Chait, and Roy Kishony. “Nonoptimal Gene Expression
Creates Latent Potential for Antibiotic Resistance.” Molecular Biology and
Evolution. Oxford University Press, 2018. https://doi.org/10.1093/molbev/msy163.
ieee: A. Palmer, R. P. Chait, and R. Kishony, “Nonoptimal gene expression creates
latent potential for antibiotic resistance,” Molecular Biology and Evolution,
vol. 35, no. 11. Oxford University Press, pp. 2669–2684, 2018.
ista: Palmer A, Chait RP, Kishony R. 2018. Nonoptimal gene expression creates latent
potential for antibiotic resistance. Molecular Biology and Evolution. 35(11),
2669–2684.
mla: Palmer, Adam, et al. “Nonoptimal Gene Expression Creates Latent Potential for
Antibiotic Resistance.” Molecular Biology and Evolution, vol. 35, no. 11,
Oxford University Press, 2018, pp. 2669–84, doi:10.1093/molbev/msy163.
short: A. Palmer, R.P. Chait, R. Kishony, Molecular Biology and Evolution 35 (2018)
2669–2684.
date_created: 2018-12-11T11:44:11Z
date_published: 2018-08-28T00:00:00Z
date_updated: 2023-10-17T11:51:06Z
day: '28'
department:
- _id: CaGu
- _id: GaTk
doi: 10.1093/molbev/msy163
external_id:
isi:
- '000452567200006'
pmid:
- '30169679'
intvolume: ' 35'
isi: 1
issue: '11'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pubmed/30169679
month: '08'
oa: 1
oa_version: Submitted Version
page: 2669 - 2684
pmid: 1
publication: Molecular Biology and Evolution
publication_identifier:
issn:
- 0737-4038
publication_status: published
publisher: Oxford University Press
publist_id: '8036'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Nonoptimal gene expression creates latent potential for antibiotic resistance
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 35
year: '2018'
...
---
_id: '190'
abstract:
- lang: eng
text: The German cockroach, Blattella germanica, is a worldwide pest that infests
buildings, including homes, restaurants, and hospitals, often living in unsanitary
conditions. As a disease vector and producer of allergens, this species has major
health and economic impacts on humans. Factors contributing to the success of
the German cockroach include its resistance to a broad range of insecticides,
immunity to many pathogens, and its ability, as an extreme generalist omnivore,
to survive on most food sources. The recently published genome shows that B. germanica
has an exceptionally high number of protein coding genes. In this study, we investigate
the functions of the 93 significantly expanded gene families with the aim to better
understand the success of B. germanica as a major pest despite such inhospitable
conditions. We find major expansions in gene families with functions related to
the detoxification of insecticides and allelochemicals, defense against pathogens,
digestion, sensory perception, and gene regulation. These expansions might have
allowed B. germanica to develop multiple resistance mechanisms to insecticides
and pathogens, and enabled a broad, flexible diet, thus explaining its success
in unsanitary conditions and under recurrent chemical control. The findings and
resources presented here provide insights for better understanding molecular mechanisms
that will facilitate more effective cockroach control.
article_processing_charge: No
article_type: original
author:
- first_name: Mark
full_name: Harrison, Mark
last_name: Harrison
- first_name: Nicolas
full_name: Arning, Nicolas
last_name: Arning
- first_name: Lucas
full_name: Kremer, Lucas
last_name: Kremer
- first_name: Guillem
full_name: Ylla, Guillem
last_name: Ylla
- first_name: Xavier
full_name: Belles, Xavier
last_name: Belles
- first_name: Erich
full_name: Bornberg Bauer, Erich
last_name: Bornberg Bauer
- first_name: Ann K
full_name: Huylmans, Ann K
id: 4C0A3874-F248-11E8-B48F-1D18A9856A87
last_name: Huylmans
orcid: 0000-0001-8871-4961
- first_name: Evelien
full_name: Jongepier, Evelien
last_name: Jongepier
- first_name: Maria
full_name: Puilachs, Maria
last_name: Puilachs
- first_name: Stephen
full_name: Richards, Stephen
last_name: Richards
- first_name: Coby
full_name: Schal, Coby
last_name: Schal
citation:
ama: 'Harrison M, Arning N, Kremer L, et al. Expansions of key protein families
in the German cockroach highlight the molecular basis of its remarkable success
as a global indoor pest. Journal of Experimental Zoology Part B: Molecular
and Developmental Evolution. 2018;330:254-264. doi:10.1002/jez.b.22824'
apa: 'Harrison, M., Arning, N., Kremer, L., Ylla, G., Belles, X., Bornberg Bauer,
E., … Schal, C. (2018). Expansions of key protein families in the German cockroach
highlight the molecular basis of its remarkable success as a global indoor pest.
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution.
Wiley. https://doi.org/10.1002/jez.b.22824'
chicago: 'Harrison, Mark, Nicolas Arning, Lucas Kremer, Guillem Ylla, Xavier Belles,
Erich Bornberg Bauer, Ann K Huylmans, et al. “Expansions of Key Protein Families
in the German Cockroach Highlight the Molecular Basis of Its Remarkable Success
as a Global Indoor Pest.” Journal of Experimental Zoology Part B: Molecular
and Developmental Evolution. Wiley, 2018. https://doi.org/10.1002/jez.b.22824.'
ieee: 'M. Harrison et al., “Expansions of key protein families in the German
cockroach highlight the molecular basis of its remarkable success as a global
indoor pest,” Journal of Experimental Zoology Part B: Molecular and Developmental
Evolution, vol. 330. Wiley, pp. 254–264, 2018.'
ista: 'Harrison M, Arning N, Kremer L, Ylla G, Belles X, Bornberg Bauer E, Huylmans
AK, Jongepier E, Puilachs M, Richards S, Schal C. 2018. Expansions of key protein
families in the German cockroach highlight the molecular basis of its remarkable
success as a global indoor pest. Journal of Experimental Zoology Part B: Molecular
and Developmental Evolution. 330, 254–264.'
mla: 'Harrison, Mark, et al. “Expansions of Key Protein Families in the German Cockroach
Highlight the Molecular Basis of Its Remarkable Success as a Global Indoor Pest.”
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution,
vol. 330, Wiley, 2018, pp. 254–64, doi:10.1002/jez.b.22824.'
short: 'M. Harrison, N. Arning, L. Kremer, G. Ylla, X. Belles, E. Bornberg Bauer,
A.K. Huylmans, E. Jongepier, M. Puilachs, S. Richards, C. Schal, Journal of Experimental
Zoology Part B: Molecular and Developmental Evolution 330 (2018) 254–264.'
date_created: 2018-12-11T11:45:06Z
date_published: 2018-07-11T00:00:00Z
date_updated: 2023-09-11T13:59:54Z
day: '11'
department:
- _id: BeVi
doi: 10.1002/jez.b.22824
external_id:
isi:
- '000443231000002'
pmid:
- '29998472'
intvolume: ' 330'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://onlinelibrary.wiley.com/doi/am-pdf/10.1002/jez.b.22824
month: '07'
oa: 1
oa_version: Submitted Version
page: 254-264
pmid: 1
publication: 'Journal of Experimental Zoology Part B: Molecular and Developmental
Evolution'
publication_status: published
publisher: Wiley
publist_id: '7730'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Expansions of key protein families in the German cockroach highlight the molecular
basis of its remarkable success as a global indoor pest
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 330
year: '2018'
...
---
_id: '192'
abstract:
- lang: eng
text: The phytohormone auxin is the information carrier in a plethora of developmental
and physiological processes in plants(1). It has been firmly established that
canonical, nuclear auxin signalling acts through regulation of gene transcription(2).
Here, we combined microfluidics, live imaging, genetic engineering and computational
modelling to reanalyse the classical case of root growth inhibition(3) by auxin.
We show that Arabidopsis roots react to addition and removal of auxin by extremely
rapid adaptation of growth rate. This process requires intracellular auxin perception
but not transcriptional reprogramming. The formation of the canonical TIR1/AFB-Aux/IAA
co-receptor complex is required for the growth regulation, hinting to a novel,
non-transcriptional branch of this signalling pathway. Our results challenge the
current understanding of root growth regulation by auxin and suggest another,
presumably non-transcriptional, signalling output of the canonical auxin pathway.
article_processing_charge: No
article_type: original
author:
- first_name: Matyas
full_name: Fendrych, Matyas
id: 43905548-F248-11E8-B48F-1D18A9856A87
last_name: Fendrych
orcid: 0000-0002-9767-8699
- first_name: Maria
full_name: Akhmanova, Maria
id: 3425EC26-F248-11E8-B48F-1D18A9856A87
last_name: Akhmanova
orcid: 0000-0003-1522-3162
- first_name: Jack
full_name: Merrin, Jack
id: 4515C308-F248-11E8-B48F-1D18A9856A87
last_name: Merrin
orcid: 0000-0001-5145-4609
- first_name: Matous
full_name: Glanc, Matous
last_name: Glanc
- first_name: Shinya
full_name: Hagihara, Shinya
last_name: Hagihara
- first_name: Koji
full_name: Takahashi, Koji
last_name: Takahashi
- first_name: Naoyuki
full_name: Uchida, Naoyuki
last_name: Uchida
- first_name: Keiko U
full_name: Torii, Keiko U
last_name: Torii
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Fendrych M, Akhmanova M, Merrin J, et al. Rapid and reversible root growth
inhibition by TIR1 auxin signalling. Nature Plants. 2018;4(7):453-459.
doi:10.1038/s41477-018-0190-1
apa: Fendrych, M., Akhmanova, M., Merrin, J., Glanc, M., Hagihara, S., Takahashi,
K., … Friml, J. (2018). Rapid and reversible root growth inhibition by TIR1 auxin
signalling. Nature Plants. Springer Nature. https://doi.org/10.1038/s41477-018-0190-1
chicago: Fendrych, Matyas, Maria Akhmanova, Jack Merrin, Matous Glanc, Shinya Hagihara,
Koji Takahashi, Naoyuki Uchida, Keiko U Torii, and Jiří Friml. “Rapid and Reversible
Root Growth Inhibition by TIR1 Auxin Signalling.” Nature Plants. Springer
Nature, 2018. https://doi.org/10.1038/s41477-018-0190-1.
ieee: M. Fendrych et al., “Rapid and reversible root growth inhibition by
TIR1 auxin signalling,” Nature Plants, vol. 4, no. 7. Springer Nature,
pp. 453–459, 2018.
ista: Fendrych M, Akhmanova M, Merrin J, Glanc M, Hagihara S, Takahashi K, Uchida
N, Torii KU, Friml J. 2018. Rapid and reversible root growth inhibition by TIR1
auxin signalling. Nature Plants. 4(7), 453–459.
mla: Fendrych, Matyas, et al. “Rapid and Reversible Root Growth Inhibition by TIR1
Auxin Signalling.” Nature Plants, vol. 4, no. 7, Springer Nature, 2018,
pp. 453–59, doi:10.1038/s41477-018-0190-1.
short: M. Fendrych, M. Akhmanova, J. Merrin, M. Glanc, S. Hagihara, K. Takahashi,
N. Uchida, K.U. Torii, J. Friml, Nature Plants 4 (2018) 453–459.
date_created: 2018-12-11T11:45:07Z
date_published: 2018-06-25T00:00:00Z
date_updated: 2023-09-15T12:11:03Z
day: '25'
department:
- _id: JiFr
- _id: DaSi
- _id: NanoFab
doi: 10.1038/s41477-018-0190-1
external_id:
isi:
- '000443221200017'
pmid:
- '29942048'
intvolume: ' 4'
isi: 1
issue: '7'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pubmed/29942048
month: '06'
oa: 1
oa_version: Submitted Version
page: 453 - 459
pmid: 1
publication: Nature Plants
publication_status: published
publisher: Springer Nature
publist_id: '7728'
quality_controlled: '1'
related_material:
link:
- description: News on IST Homepage
relation: press_release
url: https://ist.ac.at/en/news/new-mechanism-for-the-plant-hormone-auxin-discovered/
scopus_import: '1'
status: public
title: Rapid and reversible root growth inhibition by TIR1 auxin signalling
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 4
year: '2018'
...
---
_id: '193'
abstract:
- lang: eng
text: 'We show attacks on five data-independent memory-hard functions (iMHF) that
were submitted to the password hashing competition (PHC). Informally, an MHF is
a function which cannot be evaluated on dedicated hardware, like ASICs, at significantly
lower hardware and/or energy cost than evaluating a single instance on a standard
single-core architecture. Data-independent means the memory access pattern of
the function is independent of the input; this makes iMHFs harder to construct
than data-dependent ones, but the latter can be attacked by various side-channel
attacks. Following [Alwen-Blocki''16], we capture the evaluation of an iMHF as
a directed acyclic graph (DAG). The cumulative parallel pebbling complexity of
this DAG is a measure for the hardware cost of evaluating the iMHF on an ASIC.
Ideally, one would like the complexity of a DAG underlying an iMHF to be as close
to quadratic in the number of nodes of the graph as possible. Instead, we show
that (the DAGs underlying) the following iMHFs are far from this bound: Rig.v2,
TwoCats and Gambit each having an exponent no more than 1.75. Moreover, we show
that the complexity of the iMHF modes of the PHC finalists Pomelo and Lyra2 have
exponents at most 1.83 and 1.67 respectively. To show this we investigate a combinatorial
property of each underlying DAG (called its depth-robustness. By establishing
upper bounds on this property we are then able to apply the general technique
of [Alwen-Block''16] for analyzing the hardware costs of an iMHF.'
acknowledgement: Leonid Reyzin was supported in part by IST Austria and by US NSF
grants 1012910, 1012798, and 1422965; this research was performed while he was visiting
IST Austria.
article_processing_charge: No
author:
- first_name: Joel F
full_name: Alwen, Joel F
id: 2A8DFA8C-F248-11E8-B48F-1D18A9856A87
last_name: Alwen
- first_name: Peter
full_name: Gazi, Peter
last_name: Gazi
- first_name: Chethan
full_name: Kamath Hosdurg, Chethan
id: 4BD3F30E-F248-11E8-B48F-1D18A9856A87
last_name: Kamath Hosdurg
- first_name: Karen
full_name: Klein, Karen
id: 3E83A2F8-F248-11E8-B48F-1D18A9856A87
last_name: Klein
- first_name: Georg F
full_name: Osang, Georg F
id: 464B40D6-F248-11E8-B48F-1D18A9856A87
last_name: Osang
orcid: 0000-0002-8882-5116
- first_name: Krzysztof Z
full_name: Pietrzak, Krzysztof Z
id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
last_name: Pietrzak
orcid: 0000-0002-9139-1654
- first_name: Lenoid
full_name: Reyzin, Lenoid
last_name: Reyzin
- first_name: Michal
full_name: Rolinek, Michal
id: 3CB3BC06-F248-11E8-B48F-1D18A9856A87
last_name: Rolinek
- first_name: Michal
full_name: Rybar, Michal
id: 2B3E3DE8-F248-11E8-B48F-1D18A9856A87
last_name: Rybar
citation:
ama: 'Alwen JF, Gazi P, Kamath Hosdurg C, et al. On the memory hardness of data
independent password hashing functions. In: Proceedings of the 2018 on Asia
Conference on Computer and Communication Security. ACM; 2018:51-65. doi:10.1145/3196494.3196534'
apa: 'Alwen, J. F., Gazi, P., Kamath Hosdurg, C., Klein, K., Osang, G. F., Pietrzak,
K. Z., … Rybar, M. (2018). On the memory hardness of data independent password
hashing functions. In Proceedings of the 2018 on Asia Conference on Computer
and Communication Security (pp. 51–65). Incheon, Republic of Korea: ACM. https://doi.org/10.1145/3196494.3196534'
chicago: Alwen, Joel F, Peter Gazi, Chethan Kamath Hosdurg, Karen Klein, Georg F
Osang, Krzysztof Z Pietrzak, Lenoid Reyzin, Michal Rolinek, and Michal Rybar.
“On the Memory Hardness of Data Independent Password Hashing Functions.” In Proceedings
of the 2018 on Asia Conference on Computer and Communication Security, 51–65.
ACM, 2018. https://doi.org/10.1145/3196494.3196534.
ieee: J. F. Alwen et al., “On the memory hardness of data independent password
hashing functions,” in Proceedings of the 2018 on Asia Conference on Computer
and Communication Security, Incheon, Republic of Korea, 2018, pp. 51–65.
ista: 'Alwen JF, Gazi P, Kamath Hosdurg C, Klein K, Osang GF, Pietrzak KZ, Reyzin
L, Rolinek M, Rybar M. 2018. On the memory hardness of data independent password
hashing functions. Proceedings of the 2018 on Asia Conference on Computer and
Communication Security. ASIACCS: Asia Conference on Computer and Communications
Security , 51–65.'
mla: Alwen, Joel F., et al. “On the Memory Hardness of Data Independent Password
Hashing Functions.” Proceedings of the 2018 on Asia Conference on Computer
and Communication Security, ACM, 2018, pp. 51–65, doi:10.1145/3196494.3196534.
short: J.F. Alwen, P. Gazi, C. Kamath Hosdurg, K. Klein, G.F. Osang, K.Z. Pietrzak,
L. Reyzin, M. Rolinek, M. Rybar, in:, Proceedings of the 2018 on Asia Conference
on Computer and Communication Security, ACM, 2018, pp. 51–65.
conference:
end_date: 2018-06-08
location: Incheon, Republic of Korea
name: 'ASIACCS: Asia Conference on Computer and Communications Security '
start_date: 2018-06-04
date_created: 2018-12-11T11:45:07Z
date_published: 2018-06-01T00:00:00Z
date_updated: 2024-11-04T13:52:29Z
day: '01'
department:
- _id: KrPi
- _id: HeEd
- _id: VlKo
doi: 10.1145/3196494.3196534
ec_funded: 1
external_id:
isi:
- '000516620100005'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://eprint.iacr.org/2016/783
month: '06'
oa: 1
oa_version: Submitted Version
page: 51 - 65
project:
- _id: 25FBA906-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '616160'
name: 'Discrete Optimization in Computer Vision: Theory and Practice'
- _id: 258AA5B2-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '682815'
name: Teaching Old Crypto New Tricks
publication: Proceedings of the 2018 on Asia Conference on Computer and Communication
Security
publication_status: published
publisher: ACM
publist_id: '7723'
quality_controlled: '1'
scopus_import: '1'
status: public
title: On the memory hardness of data independent password hashing functions
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '195'
abstract:
- lang: eng
text: We demonstrate that identical impurities immersed in a two-dimensional many-particle
bath can be viewed as flux-tube-charged-particle composites described by fractional
statistics. In particular, we find that the bath manifests itself as an external
magnetic flux tube with respect to the impurities, and hence the time-reversal
symmetry is broken for the effective Hamiltonian describing the impurities. The
emerging flux tube acts as a statistical gauge field after a certain critical
coupling. This critical coupling corresponds to the intersection point between
the quasiparticle state and the phonon wing, where the angular momentum is transferred
from the impurity to the bath. This amounts to a novel configuration with emerging
anyons. The proposed setup paves the way to realizing anyons using electrons interacting
with superfluid helium or lattice phonons, as well as using atomic impurities
in ultracold gases.
article_number: '045402'
article_processing_charge: No
arxiv: 1
author:
- first_name: Enderalp
full_name: Yakaboylu, Enderalp
id: 38CB71F6-F248-11E8-B48F-1D18A9856A87
last_name: Yakaboylu
orcid: 0000-0001-5973-0874
- first_name: Mikhail
full_name: Lemeshko, Mikhail
id: 37CB05FA-F248-11E8-B48F-1D18A9856A87
last_name: Lemeshko
orcid: 0000-0002-6990-7802
citation:
ama: Yakaboylu E, Lemeshko M. Anyonic statistics of quantum impurities in two dimensions.
Physical Review B - Condensed Matter and Materials Physics. 2018;98(4).
doi:10.1103/PhysRevB.98.045402
apa: Yakaboylu, E., & Lemeshko, M. (2018). Anyonic statistics of quantum impurities
in two dimensions. Physical Review B - Condensed Matter and Materials Physics.
American Physical Society. https://doi.org/10.1103/PhysRevB.98.045402
chicago: Yakaboylu, Enderalp, and Mikhail Lemeshko. “Anyonic Statistics of Quantum
Impurities in Two Dimensions.” Physical Review B - Condensed Matter and Materials
Physics. American Physical Society, 2018. https://doi.org/10.1103/PhysRevB.98.045402.
ieee: E. Yakaboylu and M. Lemeshko, “Anyonic statistics of quantum impurities in
two dimensions,” Physical Review B - Condensed Matter and Materials Physics,
vol. 98, no. 4. American Physical Society, 2018.
ista: Yakaboylu E, Lemeshko M. 2018. Anyonic statistics of quantum impurities in
two dimensions. Physical Review B - Condensed Matter and Materials Physics. 98(4),
045402.
mla: Yakaboylu, Enderalp, and Mikhail Lemeshko. “Anyonic Statistics of Quantum Impurities
in Two Dimensions.” Physical Review B - Condensed Matter and Materials Physics,
vol. 98, no. 4, 045402, American Physical Society, 2018, doi:10.1103/PhysRevB.98.045402.
short: E. Yakaboylu, M. Lemeshko, Physical Review B - Condensed Matter and Materials
Physics 98 (2018).
corr_author: '1'
date_created: 2018-12-11T11:45:08Z
date_published: 2018-07-15T00:00:00Z
date_updated: 2025-04-15T06:50:28Z
day: '15'
department:
- _id: MiLe
doi: 10.1103/PhysRevB.98.045402
ec_funded: 1
external_id:
arxiv:
- '1712.00308'
isi:
- '000436939100007'
intvolume: ' 98'
isi: 1
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1712.00308
month: '07'
oa: 1
oa_version: Submitted Version
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
- _id: 26031614-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P29902
name: Quantum rotations in the presence of a many-body environment
publication: Physical Review B - Condensed Matter and Materials Physics
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Anyonic statistics of quantum impurities in two dimensions
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 98
year: '2018'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '19544'
abstract:
- lang: eng
text: Medicinal bioinorganic chemistry is a thriving field of drug research for
cancer treatment. Transition metal complexes coordinated to essential biological
scaffolds represent a highly promising class of compounds for design of novel
target-specific therapeutics. We report here the biological evaluation of a novel
Isatin-Schiff base derivative and its Cu(II) complex in several tumor cell lines
by assessing their effects on cellular metabolism, real-time cell proliferation
and induction of apoptosis. Further, the impact of compounds on the p53 protein
and expression of its target genes, including MDM2, p21/CDKN1A, and PUMA was evaluated.
Results obtained in this study provide further evidence in support of our prior
data suggesting the p53-mediated mechanism of action for Isatin-Schiff base derivatives
and their complexes and also shed light on potential use of these compounds for
stimulation of apoptosis in breast cancer cells via activation of the pro-apoptotic
PUMA gene.
article_number: '103'
article_processing_charge: Yes
article_type: original
author:
- first_name: Emil
full_name: Bulatov, Emil
last_name: Bulatov
- first_name: Regina
full_name: Sayarova, Regina
last_name: Sayarova
- first_name: Rimma
full_name: Mingaleeva, Rimma
last_name: Mingaleeva
- first_name: Regina
full_name: Miftakhova, Regina
last_name: Miftakhova
- first_name: Marina
full_name: Gomzikova, Marina
last_name: Gomzikova
- first_name: Iurii
full_name: Ignatev, Iurii
id: 2ac71786-dc7d-11ea-9b2f-c5ad4b9faff6
last_name: Ignatev
- first_name: Alexey
full_name: Petukhov, Alexey
last_name: Petukhov
- first_name: Pavel
full_name: Davidovich, Pavel
last_name: Davidovich
- first_name: Albert
full_name: Rizvanov, Albert
last_name: Rizvanov
- first_name: Nickolai A.
full_name: Barlev, Nickolai A.
last_name: Barlev
citation:
ama: Bulatov E, Sayarova R, Mingaleeva R, et al. Isatin-Schiff base-copper (II)
complex induces cell death in p53-positive tumors. Cell Death Discovery.
2018;4. doi:10.1038/s41420-018-0120-z
apa: Bulatov, E., Sayarova, R., Mingaleeva, R., Miftakhova, R., Gomzikova, M., Ignatev,
I., … Barlev, N. A. (2018). Isatin-Schiff base-copper (II) complex induces cell
death in p53-positive tumors. Cell Death Discovery. Springer Nature. https://doi.org/10.1038/s41420-018-0120-z
chicago: Bulatov, Emil, Regina Sayarova, Rimma Mingaleeva, Regina Miftakhova, Marina
Gomzikova, Iurii Ignatev, Alexey Petukhov, Pavel Davidovich, Albert Rizvanov,
and Nickolai A. Barlev. “Isatin-Schiff Base-Copper (II) Complex Induces Cell Death
in P53-Positive Tumors.” Cell Death Discovery. Springer Nature, 2018. https://doi.org/10.1038/s41420-018-0120-z.
ieee: E. Bulatov et al., “Isatin-Schiff base-copper (II) complex induces
cell death in p53-positive tumors,” Cell Death Discovery, vol. 4. Springer
Nature, 2018.
ista: Bulatov E, Sayarova R, Mingaleeva R, Miftakhova R, Gomzikova M, Ignatev I,
Petukhov A, Davidovich P, Rizvanov A, Barlev NA. 2018. Isatin-Schiff base-copper
(II) complex induces cell death in p53-positive tumors. Cell Death Discovery.
4, 103.
mla: Bulatov, Emil, et al. “Isatin-Schiff Base-Copper (II) Complex Induces Cell
Death in P53-Positive Tumors.” Cell Death Discovery, vol. 4, 103, Springer
Nature, 2018, doi:10.1038/s41420-018-0120-z.
short: E. Bulatov, R. Sayarova, R. Mingaleeva, R. Miftakhova, M. Gomzikova, I. Ignatev,
A. Petukhov, P. Davidovich, A. Rizvanov, N.A. Barlev, Cell Death Discovery 4 (2018).
date_created: 2025-04-11T01:31:42Z
date_published: 2018-11-13T00:00:00Z
date_updated: 2025-07-10T11:51:52Z
day: '13'
ddc:
- '570'
department:
- _id: GradSch
- _id: LoSw
doi: 10.1038/s41420-018-0120-z
extern: '1'
external_id:
pmid:
- '30455989 '
has_accepted_license: '1'
intvolume: ' 4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1038/s41420-018-0120-z
month: '11'
oa: 1
oa_version: Published Version
pmid: 1
publication: Cell Death Discovery
publication_identifier:
issn:
- 2058-7716
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Isatin-Schiff base-copper (II) complex induces cell death in p53-positive tumors
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 4
year: '2018'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '19706'
abstract:
- lang: eng
text: 'The importance of astrocytic l-lactate (LL) for normal functioning of neural
circuits such as those regulating learning/memory, sleep/wake state, autonomic
homeostasis, or emotional behaviour is being increasingly recognised. l-Lactate
can act on neurones as a metabolic or redox substrate, but transmembrane receptor
targets are also emerging. A comparative review of the hydroxy-carboxylic acid
receptor (HCA1, formerly known as GPR81), Olfactory Receptor Family 51 Subfamily
E Member 2 (OR51E2), and orphan receptor GPR4 highlights differences in their
LL sensitivity, pharmacology, intracellular coupling, and localisation in the
brain. In addition, a putative Gs-coupled receptor on noradrenergic neurones,
LLRx, which we previously postulated, remains to be identified. Next-generation
sequencing revealed several orphan receptors expressed in locus coeruleus neurones.
Screening of a selection of these suggests additional LL-sensitive receptors:
GPR180 which inhibits and GPR137 which activates intracellular cyclic AMP signalling
in response to LL in a heterologous expression system. To further characterise
binding of LL at LLRx, we carried out a structure–activity relationship study
which demonstrates that carboxyl and 2-hydroxyl moieties of LL are essential for
triggering d-lactate-sensitive noradrenaline release in locus coeruleus, and that
the size of the LL binding pocket is limited towards the methyl group position.
The evidence accumulating to date suggests that LL acts via multiple receptor
targets to modulate distinct brain functions.'
acknowledgement: This work was supported by grants from BBSRC BB/L019396/1, and MRC
MR/L020661/1. David Kleinfeld for his gift of CNiFER cells, Lesley Arberry for expert
technical support, Andrew Herman for support with FACS sorting.
article_processing_charge: Yes
article_type: original
author:
- first_name: Valentina
full_name: Mosienko, Valentina
last_name: Mosienko
- first_name: Seyed
full_name: Rasooli-Nejad, Seyed
last_name: Rasooli-Nejad
- first_name: Kasumi
full_name: Kishi, Kasumi
id: 3065DFC4-F248-11E8-B48F-1D18A9856A87
last_name: Kishi
- first_name: Matt
full_name: De Both, Matt
last_name: De Both
- first_name: David
full_name: Jane, David
last_name: Jane
- first_name: Matt J.
full_name: Huentelman, Matt J.
last_name: Huentelman
- first_name: Sergey
full_name: Kasparov, Sergey
last_name: Kasparov
- first_name: Anja G.
full_name: Teschemacher, Anja G.
last_name: Teschemacher
citation:
ama: Mosienko V, Rasooli-Nejad S, Kishi K, et al. Putative receptors underpinning
L-Lactate signalling in locus coeruleus. Neuroglia. 2018;1(2):365-380.
doi:10.3390/neuroglia1020025
apa: Mosienko, V., Rasooli-Nejad, S., Kishi, K., De Both, M., Jane, D., Huentelman,
M. J., … Teschemacher, A. G. (2018). Putative receptors underpinning L-Lactate
signalling in locus coeruleus. Neuroglia. MDPI. https://doi.org/10.3390/neuroglia1020025
chicago: Mosienko, Valentina, Seyed Rasooli-Nejad, Kasumi Kishi, Matt De Both, David
Jane, Matt J. Huentelman, Sergey Kasparov, and Anja G. Teschemacher. “Putative
Receptors Underpinning L-Lactate Signalling in Locus Coeruleus.” Neuroglia.
MDPI, 2018. https://doi.org/10.3390/neuroglia1020025.
ieee: V. Mosienko et al., “Putative receptors underpinning L-Lactate signalling
in locus coeruleus,” Neuroglia, vol. 1, no. 2. MDPI, pp. 365–380, 2018.
ista: Mosienko V, Rasooli-Nejad S, Kishi K, De Both M, Jane D, Huentelman MJ, Kasparov
S, Teschemacher AG. 2018. Putative receptors underpinning L-Lactate signalling
in locus coeruleus. Neuroglia. 1(2), 365–380.
mla: Mosienko, Valentina, et al. “Putative Receptors Underpinning L-Lactate Signalling
in Locus Coeruleus.” Neuroglia, vol. 1, no. 2, MDPI, 2018, pp. 365–80,
doi:10.3390/neuroglia1020025.
short: V. Mosienko, S. Rasooli-Nejad, K. Kishi, M. De Both, D. Jane, M.J. Huentelman,
S. Kasparov, A.G. Teschemacher, Neuroglia 1 (2018) 365–380.
date_created: 2025-05-18T22:02:51Z
date_published: 2018-12-01T00:00:00Z
date_updated: 2025-05-19T08:28:40Z
day: '01'
ddc:
- '570'
department:
- _id: AnKi
doi: 10.3390/neuroglia1020025
file:
- access_level: open_access
checksum: cadb56618f72edf4703b6a9855e84baa
content_type: application/pdf
creator: dernst
date_created: 2025-05-19T08:20:19Z
date_updated: 2025-05-19T08:20:19Z
file_id: '19711'
file_name: 2018_Neuroglia_Mosienko.pdf
file_size: 1909402
relation: main_file
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file_date_updated: 2025-05-19T08:20:19Z
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month: '12'
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publication: Neuroglia
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title: Putative receptors underpinning L-Lactate signalling in locus coeruleus
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