---
_id: '433'
abstract:
- lang: eng
  text: 'A thrackle is a graph drawn in the plane so that every pair of its edges
    meet exactly once: either at a common end vertex or in a proper crossing. We prove
    that any thrackle of n vertices has at most 1.3984n edges. Quasi-thrackles are
    defined similarly, except that every pair of edges that do not share a vertex
    are allowed to cross an odd number of times. It is also shown that the maximum
    number of edges of a quasi-thrackle on n vertices is 3/2(n-1), and that this bound
    is best possible for infinitely many values of n.'
alternative_title:
- LNCS
article_processing_charge: No
arxiv: 1
author:
- first_name: Radoslav
  full_name: Fulek, Radoslav
  id: 39F3FFE4-F248-11E8-B48F-1D18A9856A87
  last_name: Fulek
  orcid: 0000-0001-8485-1774
- first_name: János
  full_name: Pach, János
  last_name: Pach
citation:
  ama: 'Fulek R, Pach J. Thrackles: An improved upper bound. In: Vol 10692. Springer;
    2018:160-166. doi:<a href="https://doi.org/10.1007/978-3-319-73915-1_14">10.1007/978-3-319-73915-1_14</a>'
  apa: 'Fulek, R., &#38; Pach, J. (2018). Thrackles: An improved upper bound (Vol.
    10692, pp. 160–166). Presented at the GD: Graph Drawing and Network Visualization,
    Boston, MA, United States: Springer. <a href="https://doi.org/10.1007/978-3-319-73915-1_14">https://doi.org/10.1007/978-3-319-73915-1_14</a>'
  chicago: 'Fulek, Radoslav, and János Pach. “Thrackles: An Improved Upper Bound,”
    10692:160–66. Springer, 2018. <a href="https://doi.org/10.1007/978-3-319-73915-1_14">https://doi.org/10.1007/978-3-319-73915-1_14</a>.'
  ieee: 'R. Fulek and J. Pach, “Thrackles: An improved upper bound,” presented at
    the GD: Graph Drawing and Network Visualization, Boston, MA, United States, 2018,
    vol. 10692, pp. 160–166.'
  ista: 'Fulek R, Pach J. 2018. Thrackles: An improved upper bound. GD: Graph Drawing
    and Network Visualization, LNCS, vol. 10692, 160–166.'
  mla: 'Fulek, Radoslav, and János Pach. <i>Thrackles: An Improved Upper Bound</i>.
    Vol. 10692, Springer, 2018, pp. 160–66, doi:<a href="https://doi.org/10.1007/978-3-319-73915-1_14">10.1007/978-3-319-73915-1_14</a>.'
  short: R. Fulek, J. Pach, in:, Springer, 2018, pp. 160–166.
conference:
  end_date: 2017-09-27
  location: Boston, MA, United States
  name: 'GD: Graph Drawing and Network Visualization'
  start_date: 201-09-25
corr_author: '1'
date_created: 2018-12-11T11:46:27Z
date_published: 2018-01-21T00:00:00Z
date_updated: 2026-04-16T09:48:11Z
day: '21'
department:
- _id: UlWa
doi: 10.1007/978-3-319-73915-1_14
external_id:
  arxiv:
  - '1708.08037'
intvolume: '     10692'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1708.08037
month: '01'
oa: 1
oa_version: Submitted Version
page: 160 - 166
publication_status: published
publisher: Springer
publist_id: '7390'
quality_controlled: '1'
related_material:
  record:
  - id: '5857'
    relation: later_version
    status: public
scopus_import: '1'
status: public
title: 'Thrackles: An improved upper bound'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10692
year: '2018'
...
---
_id: '536'
abstract:
- lang: eng
  text: 'We consider the problem of consensus in the challenging classic model. In
    this model, the adversary is adaptive; it can choose which processors crash at
    any point during the course of the algorithm. Further, communication is via asynchronous
    message passing: there is no known upper bound on the time to send a message from
    one processor to another, and all messages and coin flips are seen by the adversary.
    We describe a new randomized consensus protocol with expected message complexity
    O(n2log2n) when fewer than n / 2 processes may fail by crashing. This is an almost-linear
    improvement over the best previously known protocol, and within logarithmic factors
    of a known Ω(n2) message lower bound. The protocol further ensures that no process
    sends more than O(nlog3n) messages in expectation, which is again within logarithmic
    factors of optimal. We also present a generalization of the algorithm to an arbitrary
    number of failures t, which uses expected O(nt+t2log2t) total messages. Our approach
    is to build a message-efficient, resilient mechanism for aggregating individual
    processor votes, implementing the message-passing equivalent of a weak shared
    coin. Roughly, in our protocol, a processor first announces its votes to small
    groups, then propagates them to increasingly larger groups as it generates more
    and more votes. To bound the number of messages that an individual process might
    have to send or receive, the protocol progressively increases the weight of generated
    votes. The main technical challenge is bounding the impact of votes that are still
    “in flight” (generated, but not fully propagated) on the final outcome of the
    shared coin, especially since such votes might have different weights. We achieve
    this by leveraging the structure of the algorithm, and a technical argument based
    on martingale concentration bounds. Overall, we show that it is possible to build
    an efficient message-passing implementation of a shared coin, and in the process
    (almost-optimally) solve the classic consensus problem in the asynchronous message-passing
    model.'
article_processing_charge: Yes (via OA deal)
author:
- first_name: Dan-Adrian
  full_name: Alistarh, Dan-Adrian
  id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
  last_name: Alistarh
  orcid: 0000-0003-3650-940X
- first_name: James
  full_name: Aspnes, James
  last_name: Aspnes
- first_name: Valerie
  full_name: King, Valerie
  last_name: King
- first_name: Jared
  full_name: Saia, Jared
  last_name: Saia
citation:
  ama: Alistarh D-A, Aspnes J, King V, Saia J. Communication-efficient randomized
    consensus. <i>Distributed Computing</i>. 2018;31(6):489-501. doi:<a href="https://doi.org/10.1007/s00446-017-0315-1">10.1007/s00446-017-0315-1</a>
  apa: Alistarh, D.-A., Aspnes, J., King, V., &#38; Saia, J. (2018). Communication-efficient
    randomized consensus. <i>Distributed Computing</i>. Springer. <a href="https://doi.org/10.1007/s00446-017-0315-1">https://doi.org/10.1007/s00446-017-0315-1</a>
  chicago: Alistarh, Dan-Adrian, James Aspnes, Valerie King, and Jared Saia. “Communication-Efficient
    Randomized Consensus.” <i>Distributed Computing</i>. Springer, 2018. <a href="https://doi.org/10.1007/s00446-017-0315-1">https://doi.org/10.1007/s00446-017-0315-1</a>.
  ieee: D.-A. Alistarh, J. Aspnes, V. King, and J. Saia, “Communication-efficient
    randomized consensus,” <i>Distributed Computing</i>, vol. 31, no. 6. Springer,
    pp. 489–501, 2018.
  ista: Alistarh D-A, Aspnes J, King V, Saia J. 2018. Communication-efficient randomized
    consensus. Distributed Computing. 31(6), 489–501.
  mla: Alistarh, Dan-Adrian, et al. “Communication-Efficient Randomized Consensus.”
    <i>Distributed Computing</i>, vol. 31, no. 6, Springer, 2018, pp. 489–501, doi:<a
    href="https://doi.org/10.1007/s00446-017-0315-1">10.1007/s00446-017-0315-1</a>.
  short: D.-A. Alistarh, J. Aspnes, V. King, J. Saia, Distributed Computing 31 (2018)
    489–501.
corr_author: '1'
date_created: 2018-12-11T11:47:01Z
date_published: 2018-11-01T00:00:00Z
date_updated: 2026-04-16T09:53:54Z
day: '01'
ddc:
- '000'
department:
- _id: DaAl
doi: 10.1007/s00446-017-0315-1
external_id:
  isi:
  - '000443832300005'
file:
- access_level: open_access
  checksum: 69b46e537acdcac745237ddb853fcbb5
  content_type: application/pdf
  creator: dernst
  date_created: 2019-01-22T07:25:51Z
  date_updated: 2020-07-14T12:46:38Z
  file_id: '5867'
  file_name: 2017_DistribComp_Alistarh.pdf
  file_size: 595707
  relation: main_file
file_date_updated: 2020-07-14T12:46:38Z
has_accepted_license: '1'
intvolume: '        31'
isi: 1
issue: '6'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '11'
oa: 1
oa_version: Published Version
page: 489-501
project:
- _id: B67AFEDC-15C9-11EA-A837-991A96BB2854
  name: IST Austria Open Access Fund
publication: Distributed Computing
publication_identifier:
  issn:
  - 0178-2770
publication_status: published
publisher: Springer
publist_id: '7281'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Communication-efficient randomized consensus
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 31
year: '2018'
...
---
_id: '85'
abstract:
- lang: eng
  text: Concurrent accesses to shared data structures must be synchronized to avoid
    data races. Coarse-grained synchronization, which locks the entire data structure,
    is easy to implement but does not scale. Fine-grained synchronization can scale
    well, but can be hard to reason about. Hand-over-hand locking, in which operations
    are pipelined as they traverse the data structure, combines fine-grained synchronization
    with ease of use. However, the traditional implementation suffers from inherent
    overheads. This paper introduces snapshot-based synchronization (SBS), a novel
    hand-over-hand locking mechanism. SBS decouples the synchronization state from
    the data, significantly improving cache utilization. Further, it relies on guarantees
    provided by pipelining to minimize synchronization that requires cross-thread
    communication. Snapshot-based synchronization thus scales much better than traditional
    hand-over-hand locking, while maintaining the same ease of use.
acknowledgement: Trevor Brown was supported in part by the ISF (grants 2005/17 & 1749/14)
  and by a NSERC post-doctoral fellowship.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Eran
  full_name: Gilad, Eran
  last_name: Gilad
- first_name: Trevor A
  full_name: Brown, Trevor A
  id: 3569F0A0-F248-11E8-B48F-1D18A9856A87
  last_name: Brown
- first_name: Mark
  full_name: Oskin, Mark
  last_name: Oskin
- first_name: Yoav
  full_name: Etsion, Yoav
  last_name: Etsion
citation:
  ama: 'Gilad E, Brown TA, Oskin M, Etsion Y. Snapshot based synchronization: A fast
    replacement for Hand-over-Hand locking. In: Vol 11014. Springer; 2018:465-479.
    doi:<a href="https://doi.org/10.1007/978-3-319-96983-1_33">10.1007/978-3-319-96983-1_33</a>'
  apa: 'Gilad, E., Brown, T. A., Oskin, M., &#38; Etsion, Y. (2018). Snapshot based
    synchronization: A fast replacement for Hand-over-Hand locking (Vol. 11014, pp.
    465–479). Presented at the Euro-Par: European Conference on Parallel Processing,
    Turin, Italy: Springer. <a href="https://doi.org/10.1007/978-3-319-96983-1_33">https://doi.org/10.1007/978-3-319-96983-1_33</a>'
  chicago: 'Gilad, Eran, Trevor A Brown, Mark Oskin, and Yoav Etsion. “Snapshot Based
    Synchronization: A Fast Replacement for Hand-over-Hand Locking,” 11014:465–79.
    Springer, 2018. <a href="https://doi.org/10.1007/978-3-319-96983-1_33">https://doi.org/10.1007/978-3-319-96983-1_33</a>.'
  ieee: 'E. Gilad, T. A. Brown, M. Oskin, and Y. Etsion, “Snapshot based synchronization:
    A fast replacement for Hand-over-Hand locking,” presented at the Euro-Par: European
    Conference on Parallel Processing, Turin, Italy, 2018, vol. 11014, pp. 465–479.'
  ista: 'Gilad E, Brown TA, Oskin M, Etsion Y. 2018. Snapshot based synchronization:
    A fast replacement for Hand-over-Hand locking. Euro-Par: European Conference on
    Parallel Processing, LNCS, vol. 11014, 465–479.'
  mla: 'Gilad, Eran, et al. <i>Snapshot Based Synchronization: A Fast Replacement
    for Hand-over-Hand Locking</i>. Vol. 11014, Springer, 2018, pp. 465–79, doi:<a
    href="https://doi.org/10.1007/978-3-319-96983-1_33">10.1007/978-3-319-96983-1_33</a>.'
  short: E. Gilad, T.A. Brown, M. Oskin, Y. Etsion, in:, Springer, 2018, pp. 465–479.
conference:
  end_date: 2018-08-31
  location: Turin, Italy
  name: 'Euro-Par: European Conference on Parallel Processing'
  start_date: 2018-08-27
date_created: 2018-12-11T11:44:33Z
date_published: 2018-08-01T00:00:00Z
date_updated: 2026-04-16T09:53:41Z
day: '01'
ddc:
- '000'
department:
- _id: DaAl
doi: 10.1007/978-3-319-96983-1_33
external_id:
  isi:
  - '000851042300031'
file:
- access_level: open_access
  checksum: 13a3f250be8878405e791b53c19722ad
  content_type: application/pdf
  creator: dernst
  date_created: 2019-02-12T07:40:40Z
  date_updated: 2020-07-14T12:48:14Z
  file_id: '5954'
  file_name: 2018_Brown.pdf
  file_size: 665372
  relation: main_file
file_date_updated: 2020-07-14T12:48:14Z
has_accepted_license: '1'
intvolume: '     11014'
isi: 1
language:
- iso: eng
month: '08'
oa: 1
oa_version: Preprint
page: 465 - 479
project:
- _id: 26450934-B435-11E9-9278-68D0E5697425
  name: NSERC Postdoctoral fellowship
publication_identifier:
  issn:
  - 0302-9743
publication_status: published
publisher: Springer
publist_id: '7969'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Snapshot based synchronization: A fast replacement for Hand-over-Hand locking'
type: conference
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 11014
year: '2018'
...
---
_id: '194'
abstract:
- lang: eng
  text: Ants are emerging model systems to study cellular signaling because distinct
    castes possess different physiologic phenotypes within the same colony. Here we
    studied the functionality of inotocin signaling, an insect ortholog of mammalian
    oxytocin (OT), which was recently discovered in ants. In Lasius ants, we determined
    that specialization within the colony, seasonal factors, and physiologic conditions
    down-regulated the expression of the OT-like signaling system. Given this natural
    variation, we interrogated its function using RNAi knockdowns. Next-generation
    RNA sequencing of OT-like precursor knock-down ants highlighted its role in the
    regulation of genes involved in metabolism. Knock-down ants exhibited higher walking
    activity and increased self-grooming in the brood chamber. We propose that OT-like
    signaling in ants is important for regulating metabolic processes and locomotion.
article_processing_charge: No
article_type: original
author:
- first_name: Zita
  full_name: Liutkeviciute, Zita
  last_name: Liutkeviciute
- first_name: Esther
  full_name: Gil Mansilla, Esther
  last_name: Gil Mansilla
- first_name: Thomas
  full_name: Eder, Thomas
  last_name: Eder
- first_name: Barbara E
  full_name: Casillas Perez, Barbara E
  id: 351ED2AA-F248-11E8-B48F-1D18A9856A87
  last_name: Casillas Perez
- first_name: Maria
  full_name: Giulia Di Giglio, Maria
  last_name: Giulia Di Giglio
- first_name: Edin
  full_name: Muratspahić, Edin
  last_name: Muratspahić
- first_name: Florian
  full_name: Grebien, Florian
  last_name: Grebien
- first_name: Thomas
  full_name: Rattei, Thomas
  last_name: Rattei
- first_name: Markus
  full_name: Muttenthaler, Markus
  last_name: Muttenthaler
- first_name: Sylvia
  full_name: Cremer, Sylvia
  id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
  last_name: Cremer
  orcid: 0000-0002-2193-3868
- first_name: Christian
  full_name: Gruber, Christian
  last_name: Gruber
citation:
  ama: Liutkeviciute Z, Gil Mansilla E, Eder T, et al. Oxytocin-like signaling in
    ants influences metabolic gene expression and locomotor activity. <i>The FASEB
    Journal</i>. 2018;32(12):6808-6821. doi:<a href="https://doi.org/10.1096/fj.201800443">10.1096/fj.201800443</a>
  apa: Liutkeviciute, Z., Gil Mansilla, E., Eder, T., Casillas Perez, B. E., Giulia
    Di Giglio, M., Muratspahić, E., … Gruber, C. (2018). Oxytocin-like signaling in
    ants influences metabolic gene expression and locomotor activity. <i>The FASEB
    Journal</i>. FASEB. <a href="https://doi.org/10.1096/fj.201800443">https://doi.org/10.1096/fj.201800443</a>
  chicago: Liutkeviciute, Zita, Esther Gil Mansilla, Thomas Eder, Barbara E Casillas
    Perez, Maria Giulia Di Giglio, Edin Muratspahić, Florian Grebien, et al. “Oxytocin-like
    Signaling in Ants Influences Metabolic Gene Expression and Locomotor Activity.”
    <i>The FASEB Journal</i>. FASEB, 2018. <a href="https://doi.org/10.1096/fj.201800443">https://doi.org/10.1096/fj.201800443</a>.
  ieee: Z. Liutkeviciute <i>et al.</i>, “Oxytocin-like signaling in ants influences
    metabolic gene expression and locomotor activity,” <i>The FASEB Journal</i>, vol.
    32, no. 12. FASEB, pp. 6808–6821, 2018.
  ista: Liutkeviciute Z, Gil Mansilla E, Eder T, Casillas Perez BE, Giulia Di Giglio
    M, Muratspahić E, Grebien F, Rattei T, Muttenthaler M, Cremer S, Gruber C. 2018.
    Oxytocin-like signaling in ants influences metabolic gene expression and locomotor
    activity. The FASEB Journal. 32(12), 6808–6821.
  mla: Liutkeviciute, Zita, et al. “Oxytocin-like Signaling in Ants Influences Metabolic
    Gene Expression and Locomotor Activity.” <i>The FASEB Journal</i>, vol. 32, no.
    12, FASEB, 2018, pp. 6808–21, doi:<a href="https://doi.org/10.1096/fj.201800443">10.1096/fj.201800443</a>.
  short: Z. Liutkeviciute, E. Gil Mansilla, T. Eder, B.E. Casillas Perez, M. Giulia
    Di Giglio, E. Muratspahić, F. Grebien, T. Rattei, M. Muttenthaler, S. Cremer,
    C. Gruber, The FASEB Journal 32 (2018) 6808–6821.
date_created: 2018-12-11T11:45:08Z
date_published: 2018-11-29T00:00:00Z
date_updated: 2026-04-16T09:53:18Z
day: '29'
department:
- _id: SyCr
doi: 10.1096/fj.201800443
external_id:
  isi:
  - '000449359700035'
  pmid:
  - '29939785'
intvolume: '        32'
isi: 1
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: ' https://doi.org/10.1096/fj.201800443'
month: '11'
oa: 1
oa_version: Published Version
page: 6808-6821
pmid: 1
project:
- _id: 25E3D34E-B435-11E9-9278-68D0E5697425
  name: Individual function and social role of oxytocin-like neuropeptides in ants
publication: The FASEB Journal
publication_identifier:
  issn:
  - 0892-6638
publication_status: published
publisher: FASEB
publist_id: '7721'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Oxytocin-like signaling in ants influences metabolic gene expression and locomotor
  activity
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 32
year: '2018'
...
---
_id: '312'
abstract:
- lang: eng
  text: Motivated by biological questions, we study configurations of equal spheres
    that neither pack nor cover. Placing their centers on a lattice, we define the
    soft density of the configuration by penalizing multiple overlaps. Considering
    the 1-parameter family of diagonally distorted 3-dimensional integer lattices,
    we show that the soft density is maximized at the FCC lattice.
acknowledgement: This work was partially supported by the DFG Collaborative Research
  Center TRR 109, “Discretization in Geometry and Dynamics,” through grant I02979-N35
  of the Austrian Science Fund (FWF).
article_processing_charge: No
article_type: original
author:
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
- first_name: Mabel
  full_name: Iglesias Ham, Mabel
  id: 41B58C0C-F248-11E8-B48F-1D18A9856A87
  last_name: Iglesias Ham
citation:
  ama: Edelsbrunner H, Iglesias Ham M. On the optimality of the FCC lattice for soft
    sphere packing. <i>SIAM J Discrete Math</i>. 2018;32(1):750-782. doi:<a href="https://doi.org/10.1137/16M1097201">10.1137/16M1097201</a>
  apa: Edelsbrunner, H., &#38; Iglesias Ham, M. (2018). On the optimality of the FCC
    lattice for soft sphere packing. <i>SIAM J Discrete Math</i>. Society for Industrial
    and Applied Mathematics . <a href="https://doi.org/10.1137/16M1097201">https://doi.org/10.1137/16M1097201</a>
  chicago: Edelsbrunner, Herbert, and Mabel Iglesias Ham. “On the Optimality of the
    FCC Lattice for Soft Sphere Packing.” <i>SIAM J Discrete Math</i>. Society for
    Industrial and Applied Mathematics , 2018. <a href="https://doi.org/10.1137/16M1097201">https://doi.org/10.1137/16M1097201</a>.
  ieee: H. Edelsbrunner and M. Iglesias Ham, “On the optimality of the FCC lattice
    for soft sphere packing,” <i>SIAM J Discrete Math</i>, vol. 32, no. 1. Society
    for Industrial and Applied Mathematics , pp. 750–782, 2018.
  ista: Edelsbrunner H, Iglesias Ham M. 2018. On the optimality of the FCC lattice
    for soft sphere packing. SIAM J Discrete Math. 32(1), 750–782.
  mla: Edelsbrunner, Herbert, and Mabel Iglesias Ham. “On the Optimality of the FCC
    Lattice for Soft Sphere Packing.” <i>SIAM J Discrete Math</i>, vol. 32, no. 1,
    Society for Industrial and Applied Mathematics , 2018, pp. 750–82, doi:<a href="https://doi.org/10.1137/16M1097201">10.1137/16M1097201</a>.
  short: H. Edelsbrunner, M. Iglesias Ham, SIAM J Discrete Math 32 (2018) 750–782.
date_created: 2018-12-11T11:45:46Z
date_published: 2018-03-29T00:00:00Z
date_updated: 2026-04-16T09:53:02Z
day: '29'
department:
- _id: HeEd
doi: 10.1137/16M1097201
external_id:
  isi:
  - '000428958900038'
intvolume: '        32'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://pdfs.semanticscholar.org/d2d5/6da00fbc674e6a8b1bb9d857167e54200dc6.pdf
month: '03'
oa: 1
oa_version: Submitted Version
page: 750 - 782
project:
- _id: 2561EBF4-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I02979-N35
  name: Persistence and stability of geometric complexes
publication: SIAM J Discrete Math
publication_identifier:
  issn:
  - 0895-4801
publication_status: published
publisher: 'Society for Industrial and Applied Mathematics '
publist_id: '7553'
quality_controlled: '1'
scopus_import: '1'
status: public
title: On the optimality of the FCC lattice for soft sphere packing
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 32
year: '2018'
...
---
_id: '140'
abstract:
- lang: eng
  text: Reachability analysis is difficult for hybrid automata with affine differential
    equations, because the reach set needs to be approximated. Promising abstraction
    techniques usually employ interval methods or template polyhedra. Interval methods
    account for dense time and guarantee soundness, and there are interval-based tools
    that overapproximate affine flowpipes. But interval methods impose bounded and
    rigid shapes, which make refinement expensive and fixpoint detection difficult.
    Template polyhedra, on the other hand, can be adapted flexibly and can be unbounded,
    but sound template refinement for unbounded reachability analysis has been implemented
    only for systems with piecewise constant dynamics. We capitalize on the advantages
    of both techniques, combining interval arithmetic and template polyhedra, using
    the former to abstract time and the latter to abstract space. During a CEGAR loop,
    whenever a spurious error trajectory is found, we compute additional space constraints
    and split time intervals, and use these space-time interpolants to eliminate the
    counterexample. Space-time interpolation offers a lazy, flexible framework for
    increasing precision while guaranteeing soundness, both for error avoidance and
    fixpoint detection. To the best of out knowledge, this is the first abstraction
    refinement scheme for the reachability analysis over unbounded and dense time
    of affine hybrid systems, which is both sound and automatic. We demonstrate the
    effectiveness of our algorithm with several benchmark examples, which cannot be
    handled by other tools.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Goran
  full_name: Frehse, Goran
  last_name: Frehse
- first_name: Mirco
  full_name: Giacobbe, Mirco
  id: 3444EA5E-F248-11E8-B48F-1D18A9856A87
  last_name: Giacobbe
  orcid: 0000-0001-8180-0904
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
citation:
  ama: 'Frehse G, Giacobbe M, Henzinger TA. Space-time interpolants. In: Vol 10981.
    Springer; 2018:468-486. doi:<a href="https://doi.org/10.1007/978-3-319-96145-3_25">10.1007/978-3-319-96145-3_25</a>'
  apa: 'Frehse, G., Giacobbe, M., &#38; Henzinger, T. A. (2018). Space-time interpolants
    (Vol. 10981, pp. 468–486). Presented at the CAV: Computer Aided Verification,
    Oxford, United Kingdom: Springer. <a href="https://doi.org/10.1007/978-3-319-96145-3_25">https://doi.org/10.1007/978-3-319-96145-3_25</a>'
  chicago: Frehse, Goran, Mirco Giacobbe, and Thomas A Henzinger. “Space-Time Interpolants,”
    10981:468–86. Springer, 2018. <a href="https://doi.org/10.1007/978-3-319-96145-3_25">https://doi.org/10.1007/978-3-319-96145-3_25</a>.
  ieee: 'G. Frehse, M. Giacobbe, and T. A. Henzinger, “Space-time interpolants,” presented
    at the CAV: Computer Aided Verification, Oxford, United Kingdom, 2018, vol. 10981,
    pp. 468–486.'
  ista: 'Frehse G, Giacobbe M, Henzinger TA. 2018. Space-time interpolants. CAV: Computer
    Aided Verification, LNCS, vol. 10981, 468–486.'
  mla: Frehse, Goran, et al. <i>Space-Time Interpolants</i>. Vol. 10981, Springer,
    2018, pp. 468–86, doi:<a href="https://doi.org/10.1007/978-3-319-96145-3_25">10.1007/978-3-319-96145-3_25</a>.
  short: G. Frehse, M. Giacobbe, T.A. Henzinger, in:, Springer, 2018, pp. 468–486.
conference:
  end_date: 2018-07-17
  location: Oxford, United Kingdom
  name: 'CAV: Computer Aided Verification'
  start_date: 2018-07-14
date_created: 2018-12-11T11:44:50Z
date_published: 2018-07-18T00:00:00Z
date_updated: 2026-04-16T09:55:04Z
day: '18'
ddc:
- '005'
department:
- _id: ToHe
doi: 10.1007/978-3-319-96145-3_25
external_id:
  isi:
  - '000491481600025'
file:
- access_level: open_access
  checksum: 6dca832f575d6b3f0ea9dff56f579142
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:17:53Z
  date_updated: 2020-07-14T12:44:50Z
  file_id: '5310'
  file_name: IST-2018-1010-v1+1_space-time_interpolants.pdf
  file_size: 563710
  relation: main_file
file_date_updated: 2020-07-14T12:44:50Z
has_accepted_license: '1'
intvolume: '     10981'
isi: 1
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 468 - 486
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
- _id: 25F5A88A-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S11402-N23
  name: Moderne Concurrency Paradigms
publication_identifier:
  issn:
  - 0302-9743
publication_status: published
publisher: Springer
publist_id: '7783'
pubrep_id: '1010'
quality_controlled: '1'
related_material:
  record:
  - id: '6894'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Space-time interpolants
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 10981
year: '2018'
...
---
_id: '5788'
abstract:
- lang: eng
  text: In two-player games on graphs, the players move a token through a graph to
    produce an infinite path, which determines the winner or payoff of the game. Such
    games are central in formal verification since they model the interaction between
    a non-terminating system and its environment. We study bidding games in which
    the players bid for the right to move the token. Two bidding rules have been defined.
    In Richman bidding, in each round, the players simultaneously submit bids, and
    the higher bidder moves the token and pays the other player. Poorman bidding is
    similar except that the winner of the bidding pays the “bank” rather than the
    other player. While poorman reachability games have been studied before, we present,
    for the first time, results on infinite-duration poorman games. A central quantity
    in these games is the ratio between the two players’ initial budgets. The questions
    we study concern a necessary and sufficient ratio with which a player can achieve
    a goal. For reachability objectives, such threshold ratios are known to exist
    for both bidding rules. We show that the properties of poorman reachability games
    extend to complex qualitative objectives such as parity, similarly to the Richman
    case. Our most interesting results concern quantitative poorman games, namely
    poorman mean-payoff games, where we construct optimal strategies depending on
    the initial ratio, by showing a connection with random-turn based games. The connection
    in itself is interesting, because it does not hold for reachability poorman games.
    We also solve the complexity problems that arise in poorman bidding games.
alternative_title:
- LNCS
article_processing_charge: No
arxiv: 1
author:
- first_name: Guy
  full_name: Avni, Guy
  id: 463C8BC2-F248-11E8-B48F-1D18A9856A87
  last_name: Avni
  orcid: 0000-0001-5588-8287
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Rasmus
  full_name: Ibsen-Jensen, Rasmus
  id: 3B699956-F248-11E8-B48F-1D18A9856A87
  last_name: Ibsen-Jensen
  orcid: 0000-0003-4783-0389
citation:
  ama: 'Avni G, Henzinger TA, Ibsen-Jensen R. Infinite-duration poorman-bidding games.
    In: Vol 11316. Springer; 2018:21-36. doi:<a href="https://doi.org/10.1007/978-3-030-04612-5_2">10.1007/978-3-030-04612-5_2</a>'
  apa: 'Avni, G., Henzinger, T. A., &#38; Ibsen-Jensen, R. (2018). Infinite-duration
    poorman-bidding games (Vol. 11316, pp. 21–36). Presented at the 14th International
    Conference on Web and Internet Economics, WINE, Oxford, UK: Springer. <a href="https://doi.org/10.1007/978-3-030-04612-5_2">https://doi.org/10.1007/978-3-030-04612-5_2</a>'
  chicago: Avni, Guy, Thomas A Henzinger, and Rasmus Ibsen-Jensen. “Infinite-Duration
    Poorman-Bidding Games,” 11316:21–36. Springer, 2018. <a href="https://doi.org/10.1007/978-3-030-04612-5_2">https://doi.org/10.1007/978-3-030-04612-5_2</a>.
  ieee: G. Avni, T. A. Henzinger, and R. Ibsen-Jensen, “Infinite-duration poorman-bidding
    games,” presented at the 14th International Conference on Web and Internet Economics,
    WINE, Oxford, UK, 2018, vol. 11316, pp. 21–36.
  ista: Avni G, Henzinger TA, Ibsen-Jensen R. 2018. Infinite-duration poorman-bidding
    games. 14th International Conference on Web and Internet Economics, WINE, LNCS,
    vol. 11316, 21–36.
  mla: Avni, Guy, et al. <i>Infinite-Duration Poorman-Bidding Games</i>. Vol. 11316,
    Springer, 2018, pp. 21–36, doi:<a href="https://doi.org/10.1007/978-3-030-04612-5_2">10.1007/978-3-030-04612-5_2</a>.
  short: G. Avni, T.A. Henzinger, R. Ibsen-Jensen, in:, Springer, 2018, pp. 21–36.
conference:
  end_date: 2018-12-17
  location: Oxford, UK
  name: 14th International Conference on Web and Internet Economics, WINE
  start_date: 2018-12-15
date_created: 2018-12-30T22:59:14Z
date_published: 2018-11-21T00:00:00Z
date_updated: 2026-04-16T09:54:39Z
day: '21'
department:
- _id: ToHe
doi: 10.1007/978-3-030-04612-5_2
external_id:
  arxiv:
  - '1804.04372'
  isi:
  - '000865933000002'
intvolume: '     11316'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1804.04372
month: '11'
oa: 1
oa_version: Preprint
page: 21-36
project:
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Z211
  name: Formal methods for the design and analysis of complex systems
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
- _id: 264B3912-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: M02369
  name: Formal Methods meets Algorithmic Game Theory
publication_identifier:
  isbn:
  - '9783030046118'
  issn:
  - 0302-9743
publisher: Springer
quality_controlled: '1'
scopus_import: '1'
status: public
title: Infinite-duration poorman-bidding games
type: conference
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 11316
year: '2018'
...
---
_id: '5679'
abstract:
- lang: eng
  text: We study the almost-sure termination problem for probabilistic programs. First,
    we show that supermartingales with lower bounds on conditional absolute difference
    provide a sound approach for the almost-sure termination problem. Moreover, using
    this approach we can obtain explicit optimal bounds on tail probabilities of non-termination
    within a given number of steps. Second, we present a new approach based on Central
    Limit Theorem for the almost-sure termination problem, and show that this approach
    can establish almost-sure termination of programs which none of the existing approaches
    can handle. Finally, we discuss algorithmic approaches for the two above methods
    that lead to automated analysis techniques for almost-sure termination of probabilistic
    programs.
alternative_title:
- LNCS
article_processing_charge: No
arxiv: 1
author:
- first_name: Mingzhang
  full_name: Huang, Mingzhang
  last_name: Huang
- first_name: Hongfei
  full_name: Fu, Hongfei
  last_name: Fu
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
citation:
  ama: 'Huang M, Fu H, Chatterjee K. New approaches for almost-sure termination of
    probabilistic programs. In: Ryu S, ed. Vol 11275. Springer; 2018:181-201. doi:<a
    href="https://doi.org/10.1007/978-3-030-02768-1_11">10.1007/978-3-030-02768-1_11</a>'
  apa: 'Huang, M., Fu, H., &#38; Chatterjee, K. (2018). New approaches for almost-sure
    termination of probabilistic programs. In S. Ryu (Ed.) (Vol. 11275, pp. 181–201).
    Presented at the 16th Asian Symposium on Programming Languages and Systems, APLAS,
    Wellington, New Zealand: Springer. <a href="https://doi.org/10.1007/978-3-030-02768-1_11">https://doi.org/10.1007/978-3-030-02768-1_11</a>'
  chicago: Huang, Mingzhang, Hongfei Fu, and Krishnendu Chatterjee. “New Approaches
    for Almost-Sure Termination of Probabilistic Programs.” edited by Sukyoung Ryu,
    11275:181–201. Springer, 2018. <a href="https://doi.org/10.1007/978-3-030-02768-1_11">https://doi.org/10.1007/978-3-030-02768-1_11</a>.
  ieee: M. Huang, H. Fu, and K. Chatterjee, “New approaches for almost-sure termination
    of probabilistic programs,” presented at the 16th Asian Symposium on Programming
    Languages and Systems, APLAS, Wellington, New Zealand, 2018, vol. 11275, pp. 181–201.
  ista: Huang M, Fu H, Chatterjee K. 2018. New approaches for almost-sure termination
    of probabilistic programs. 16th Asian Symposium on Programming Languages and Systems,
    APLAS, LNCS, vol. 11275, 181–201.
  mla: Huang, Mingzhang, et al. <i>New Approaches for Almost-Sure Termination of Probabilistic
    Programs</i>. Edited by Sukyoung Ryu, vol. 11275, Springer, 2018, pp. 181–201,
    doi:<a href="https://doi.org/10.1007/978-3-030-02768-1_11">10.1007/978-3-030-02768-1_11</a>.
  short: M. Huang, H. Fu, K. Chatterjee, in:, S. Ryu (Ed.), Springer, 2018, pp. 181–201.
conference:
  end_date: 2018-12-06
  location: Wellington, New Zealand
  name: 16th Asian Symposium on Programming Languages and Systems, APLAS
  start_date: 2018-12-02
date_created: 2018-12-16T22:59:20Z
date_published: 2018-12-01T00:00:00Z
date_updated: 2026-04-16T09:54:21Z
day: '01'
department:
- _id: KrCh
doi: 10.1007/978-3-030-02768-1_11
editor:
- first_name: Sukyoung
  full_name: Ryu, Sukyoung
  last_name: Ryu
external_id:
  arxiv:
  - '1806.06683'
  isi:
  - '000916310900011'
intvolume: '     11275'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://arxiv.org/abs/1806.06683
month: '12'
oa: 1
oa_version: Preprint
page: 181-201
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
- _id: 25892FC0-B435-11E9-9278-68D0E5697425
  grant_number: ICT15-003
  name: Efficient Algorithms for Computer Aided Verification
publication_identifier:
  isbn:
  - '9783030027674'
  issn:
  - 0302-9743
publisher: Springer
quality_controlled: '1'
scopus_import: '1'
status: public
title: New approaches for almost-sure termination of probabilistic programs
type: conference
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 11275
year: '2018'
...
---
_id: '5672'
abstract:
- lang: eng
  text: The release of IgM is the first line of an antibody response and precedes
    the generation of high affinity IgG in germinal centers. Once secreted by freshly
    activated plasmablasts, IgM is released into the efferent lymph of reactive lymph
    nodes as early as 3 d after immunization. As pentameric IgM has an enormous size
    of 1,000 kD, its diffusibility is low, and one might wonder how it can pass through
    the densely lymphocyte-packed environment of a lymph node parenchyma in order
    to reach its exit. In this issue of JEM, Thierry et al. show that, in order to
    reach the blood stream, IgM molecules take a specific micro-anatomical route via
    lymph node conduits.
article_processing_charge: No
author:
- first_name: Anne
  full_name: Reversat, Anne
  id: 35B76592-F248-11E8-B48F-1D18A9856A87
  last_name: Reversat
  orcid: 0000-0003-0666-8928
- first_name: Michael K
  full_name: Sixt, Michael K
  id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
  last_name: Sixt
  orcid: 0000-0002-6620-9179
citation:
  ama: Reversat A, Sixt MK. IgM’s exit route. <i>Journal of Experimental Medicine</i>.
    2018;215(12):2959-2961. doi:<a href="https://doi.org/10.1084/jem.20181934">10.1084/jem.20181934</a>
  apa: Reversat, A., &#38; Sixt, M. K. (2018). IgM’s exit route. <i>Journal of Experimental
    Medicine</i>. Rockefeller University Press. <a href="https://doi.org/10.1084/jem.20181934">https://doi.org/10.1084/jem.20181934</a>
  chicago: Reversat, Anne, and Michael K Sixt. “IgM’s Exit Route.” <i>Journal of Experimental
    Medicine</i>. Rockefeller University Press, 2018. <a href="https://doi.org/10.1084/jem.20181934">https://doi.org/10.1084/jem.20181934</a>.
  ieee: A. Reversat and M. K. Sixt, “IgM’s exit route,” <i>Journal of Experimental
    Medicine</i>, vol. 215, no. 12. Rockefeller University Press, pp. 2959–2961, 2018.
  ista: Reversat A, Sixt MK. 2018. IgM’s exit route. Journal of Experimental Medicine.
    215(12), 2959–2961.
  mla: Reversat, Anne, and Michael K. Sixt. “IgM’s Exit Route.” <i>Journal of Experimental
    Medicine</i>, vol. 215, no. 12, Rockefeller University Press, 2018, pp. 2959–61,
    doi:<a href="https://doi.org/10.1084/jem.20181934">10.1084/jem.20181934</a>.
  short: A. Reversat, M.K. Sixt, Journal of Experimental Medicine 215 (2018) 2959–2961.
date_created: 2018-12-16T22:59:18Z
date_published: 2018-11-20T00:00:00Z
date_updated: 2026-04-16T09:54:07Z
day: '20'
ddc:
- '570'
department:
- _id: MiSi
doi: 10.1084/jem.20181934
external_id:
  isi:
  - '000451920600002'
file:
- access_level: open_access
  checksum: 687beea1d64c213f4cb9e3c29ec11a14
  content_type: application/pdf
  creator: dernst
  date_created: 2019-02-06T08:49:52Z
  date_updated: 2020-07-14T12:47:09Z
  file_id: '5931'
  file_name: 2018_JournalExperMed_Reversat.pdf
  file_size: 1216437
  relation: main_file
file_date_updated: 2020-07-14T12:47:09Z
has_accepted_license: '1'
intvolume: '       215'
isi: 1
issue: '12'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-sa/4.0/
month: '11'
oa: 1
oa_version: Published Version
page: 2959-2961
publication: Journal of Experimental Medicine
publication_identifier:
  issn:
  - 0022-1007
publication_status: published
publisher: Rockefeller University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: IgM's exit route
tmp:
  image: /images/cc_by_nc_sa.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
    BY-NC-SA 4.0)
  short: CC BY-NC-SA (4.0)
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 215
year: '2018'
...
---
_id: '703'
abstract:
- lang: eng
  text: We consider the NP-hard problem of MAP-inference for undirected discrete graphical
    models. We propose a polynomial time and practically efficient algorithm for finding
    a part of its optimal solution. Specifically, our algorithm marks some labels
    of the considered graphical model either as (i) optimal, meaning that they belong
    to all optimal solutions of the inference problem; (ii) non-optimal if they provably
    do not belong to any solution. With access to an exact solver of a linear programming
    relaxation to the MAP-inference problem, our algorithm marks the maximal possible
    (in a specified sense) number of labels. We also present a version of the algorithm,
    which has access to a suboptimal dual solver only and still can ensure the (non-)optimality
    for the marked labels, although the overall number of the marked labels may decrease.
    We propose an efficient implementation, which runs in time comparable to a single
    run of a suboptimal dual solver. Our method is well-scalable and shows state-of-the-art
    results on computational benchmarks from machine learning and computer vision.
article_processing_charge: No
arxiv: 1
author:
- first_name: Alexander
  full_name: Shekhovtsov, Alexander
  last_name: Shekhovtsov
- first_name: Paul
  full_name: Swoboda, Paul
  id: 446560C6-F248-11E8-B48F-1D18A9856A87
  last_name: Swoboda
- first_name: Bogdan
  full_name: Savchynskyy, Bogdan
  last_name: Savchynskyy
citation:
  ama: Shekhovtsov A, Swoboda P, Savchynskyy B. Maximum persistency via iterative
    relaxed inference with graphical models. <i>IEEE Transactions on Pattern Analysis
    and Machine Intelligence</i>. 2018;40(7):1668-1682. doi:<a href="https://doi.org/10.1109/TPAMI.2017.2730884">10.1109/TPAMI.2017.2730884</a>
  apa: Shekhovtsov, A., Swoboda, P., &#38; Savchynskyy, B. (2018). Maximum persistency
    via iterative relaxed inference with graphical models. <i>IEEE Transactions on
    Pattern Analysis and Machine Intelligence</i>. IEEE. <a href="https://doi.org/10.1109/TPAMI.2017.2730884">https://doi.org/10.1109/TPAMI.2017.2730884</a>
  chicago: Shekhovtsov, Alexander, Paul Swoboda, and Bogdan Savchynskyy. “Maximum
    Persistency via Iterative Relaxed Inference with Graphical Models.” <i>IEEE Transactions
    on Pattern Analysis and Machine Intelligence</i>. IEEE, 2018. <a href="https://doi.org/10.1109/TPAMI.2017.2730884">https://doi.org/10.1109/TPAMI.2017.2730884</a>.
  ieee: A. Shekhovtsov, P. Swoboda, and B. Savchynskyy, “Maximum persistency via iterative
    relaxed inference with graphical models,” <i>IEEE Transactions on Pattern Analysis
    and Machine Intelligence</i>, vol. 40, no. 7. IEEE, pp. 1668–1682, 2018.
  ista: Shekhovtsov A, Swoboda P, Savchynskyy B. 2018. Maximum persistency via iterative
    relaxed inference with graphical models. IEEE Transactions on Pattern Analysis
    and Machine Intelligence. 40(7), 1668–1682.
  mla: Shekhovtsov, Alexander, et al. “Maximum Persistency via Iterative Relaxed Inference
    with Graphical Models.” <i>IEEE Transactions on Pattern Analysis and Machine Intelligence</i>,
    vol. 40, no. 7, IEEE, 2018, pp. 1668–82, doi:<a href="https://doi.org/10.1109/TPAMI.2017.2730884">10.1109/TPAMI.2017.2730884</a>.
  short: A. Shekhovtsov, P. Swoboda, B. Savchynskyy, IEEE Transactions on Pattern
    Analysis and Machine Intelligence 40 (2018) 1668–1682.
corr_author: '1'
date_created: 2018-12-11T11:48:01Z
date_published: 2018-07-01T00:00:00Z
date_updated: 2026-04-16T09:54:52Z
day: '01'
department:
- _id: VlKo
doi: 10.1109/TPAMI.2017.2730884
external_id:
  arxiv:
  - '1508.07902'
  isi:
  - '000434294800010'
intvolume: '        40'
isi: 1
issue: '7'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1508.07902
month: '07'
oa: 1
oa_version: Preprint
page: 1668-1682
publication: IEEE Transactions on Pattern Analysis and Machine Intelligence
publication_identifier:
  issn:
  - 0162-8828
publication_status: published
publisher: IEEE
publist_id: '6992'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Maximum persistency via iterative relaxed inference with graphical models
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 40
year: '2018'
...
---
_id: '6941'
abstract:
- lang: eng
  text: "Bitcoin has become the most successful cryptocurrency ever deployed, and
    its most distinctive feature is that it is decentralized. Its underlying protocol
    (Nakamoto consensus) achieves this by using proof of work, which has the drawback
    that it causes the consumption of vast amounts of energy to maintain the ledger.
    Moreover, Bitcoin mining dynamics have become less distributed over time.\r\n\r\nTowards
    addressing these issues, we propose SpaceMint, a cryptocurrency based on proofs
    of space instead of proofs of work. Miners in SpaceMint dedicate disk space rather
    than computation. We argue that SpaceMint’s design solves or alleviates several
    of Bitcoin’s issues: most notably, its large energy consumption. SpaceMint also
    rewards smaller miners fairly according to their contribution to the network,
    thus incentivizing more distributed participation.\r\n\r\nThis paper adapts proof
    of space to enable its use in cryptocurrency, studies the attacks that can arise
    against a Bitcoin-like blockchain that uses proof of space, and proposes a new
    blockchain format and transaction types to address these attacks. Our prototype
    shows that initializing 1 TB for mining takes about a day (a one-off setup cost),
    and miners spend on average just a fraction of a second per block mined. Finally,
    we provide a game-theoretic analysis modeling SpaceMint as an extensive game (the
    canonical game-theoretic notion for games that take place over time) and show
    that this stylized game satisfies a strong equilibrium notion, thereby arguing
    for SpaceMint ’s stability and consensus."
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Sunoo
  full_name: Park, Sunoo
  last_name: Park
- first_name: Albert
  full_name: Kwon, Albert
  last_name: Kwon
- first_name: Georg
  full_name: Fuchsbauer, Georg
  id: 46B4C3EE-F248-11E8-B48F-1D18A9856A87
  last_name: Fuchsbauer
- first_name: Peter
  full_name: Gazi, Peter
  id: 3E0BFE38-F248-11E8-B48F-1D18A9856A87
  last_name: Gazi
- first_name: Joel F
  full_name: Alwen, Joel F
  id: 2A8DFA8C-F248-11E8-B48F-1D18A9856A87
  last_name: Alwen
- first_name: Krzysztof Z
  full_name: Pietrzak, Krzysztof Z
  id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
  last_name: Pietrzak
  orcid: 0000-0002-9139-1654
citation:
  ama: 'Park S, Kwon A, Fuchsbauer G, Gazi P, Alwen JF, Pietrzak KZ. SpaceMint: A
    cryptocurrency based on proofs of space. In: <i>22nd International Conference
    on Financial Cryptography and Data Security</i>. Vol 10957. Springer Nature; 2018:480-499.
    doi:<a href="https://doi.org/10.1007/978-3-662-58387-6_26">10.1007/978-3-662-58387-6_26</a>'
  apa: 'Park, S., Kwon, A., Fuchsbauer, G., Gazi, P., Alwen, J. F., &#38; Pietrzak,
    K. Z. (2018). SpaceMint: A cryptocurrency based on proofs of space. In <i>22nd
    International Conference on Financial Cryptography and Data Security</i> (Vol.
    10957, pp. 480–499). Nieuwpoort, Curacao: Springer Nature. <a href="https://doi.org/10.1007/978-3-662-58387-6_26">https://doi.org/10.1007/978-3-662-58387-6_26</a>'
  chicago: 'Park, Sunoo, Albert Kwon, Georg Fuchsbauer, Peter Gazi, Joel F Alwen,
    and Krzysztof Z Pietrzak. “SpaceMint: A Cryptocurrency Based on Proofs of Space.”
    In <i>22nd International Conference on Financial Cryptography and Data Security</i>,
    10957:480–99. Springer Nature, 2018. <a href="https://doi.org/10.1007/978-3-662-58387-6_26">https://doi.org/10.1007/978-3-662-58387-6_26</a>.'
  ieee: 'S. Park, A. Kwon, G. Fuchsbauer, P. Gazi, J. F. Alwen, and K. Z. Pietrzak,
    “SpaceMint: A cryptocurrency based on proofs of space,” in <i>22nd International
    Conference on Financial Cryptography and Data Security</i>, Nieuwpoort, Curacao,
    2018, vol. 10957, pp. 480–499.'
  ista: 'Park S, Kwon A, Fuchsbauer G, Gazi P, Alwen JF, Pietrzak KZ. 2018. SpaceMint:
    A cryptocurrency based on proofs of space. 22nd International Conference on Financial
    Cryptography and Data Security. FC: Financial Cryptography and Data Security,
    LNCS, vol. 10957, 480–499.'
  mla: 'Park, Sunoo, et al. “SpaceMint: A Cryptocurrency Based on Proofs of Space.”
    <i>22nd International Conference on Financial Cryptography and Data Security</i>,
    vol. 10957, Springer Nature, 2018, pp. 480–99, doi:<a href="https://doi.org/10.1007/978-3-662-58387-6_26">10.1007/978-3-662-58387-6_26</a>.'
  short: S. Park, A. Kwon, G. Fuchsbauer, P. Gazi, J.F. Alwen, K.Z. Pietrzak, in:,
    22nd International Conference on Financial Cryptography and Data Security, Springer
    Nature, 2018, pp. 480–499.
conference:
  end_date: 2018-03-02
  location: Nieuwpoort, Curacao
  name: 'FC: Financial Cryptography and Data Security'
  start_date: 2018-02-26
date_created: 2019-10-14T06:35:38Z
date_published: 2018-12-07T00:00:00Z
date_updated: 2026-04-16T10:30:49Z
day: '07'
department:
- _id: KrPi
doi: 10.1007/978-3-662-58387-6_26
ec_funded: 1
external_id:
  isi:
  - '000540656400026'
intvolume: '     10957'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://eprint.iacr.org/2015/528
month: '12'
oa: 1
oa_version: Submitted Version
page: 480-499
project:
- _id: 258AA5B2-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '682815'
  name: Teaching Old Crypto New Tricks
publication: 22nd International Conference on Financial Cryptography and Data Security
publication_identifier:
  eisbn:
  - '9783662583876'
  eissn:
  - 1611-3349
  isbn:
  - '9783662583869'
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'SpaceMint: A cryptocurrency based on proofs of space'
type: conference
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 10957
year: '2018'
...
---
_id: '6525'
abstract:
- lang: eng
  text: This chapter finds an agreement of equivariant indices of semi-classical homomorphisms
    between pairwise mirror branes in the GL2 Higgs moduli space on a Riemann surface.
    On one side of the agreement, components of the Lagrangian brane of U(1,1) Higgs
    bundles, whose mirror was proposed by Hitchin to be certain even exterior powers
    of the hyperholomorphic Dirac bundle on the SL2 Higgs moduli space, are present.
    The agreement arises from a mysterious functional equation. This gives strong
    computational evidence for Hitchin’s proposal.
article_processing_charge: No
author:
- first_name: Tamás
  full_name: Hausel, Tamás
  id: 4A0666D8-F248-11E8-B48F-1D18A9856A87
  last_name: Hausel
  orcid: 0000-0002-9582-2634
- first_name: Anton
  full_name: Mellit, Anton
  id: 388D3134-F248-11E8-B48F-1D18A9856A87
  last_name: Mellit
- first_name: Du
  full_name: Pei, Du
  last_name: Pei
citation:
  ama: 'Hausel T, Mellit A, Pei D. Mirror symmetry with branes by equivariant verlinde
    formulas. In: <i>Geometry and Physics: Volume I</i>. Oxford University Press;
    2018:189-218. doi:<a href="https://doi.org/10.1093/oso/9780198802013.003.0009">10.1093/oso/9780198802013.003.0009</a>'
  apa: 'Hausel, T., Mellit, A., &#38; Pei, D. (2018). Mirror symmetry with branes
    by equivariant verlinde formulas. In <i>Geometry and Physics: Volume I</i> (pp.
    189–218). Oxford University Press. <a href="https://doi.org/10.1093/oso/9780198802013.003.0009">https://doi.org/10.1093/oso/9780198802013.003.0009</a>'
  chicago: 'Hausel, Tamás, Anton Mellit, and Du Pei. “Mirror Symmetry with Branes
    by Equivariant Verlinde Formulas.” In <i>Geometry and Physics: Volume I</i>, 189–218.
    Oxford University Press, 2018. <a href="https://doi.org/10.1093/oso/9780198802013.003.0009">https://doi.org/10.1093/oso/9780198802013.003.0009</a>.'
  ieee: 'T. Hausel, A. Mellit, and D. Pei, “Mirror symmetry with branes by equivariant
    verlinde formulas,” in <i>Geometry and Physics: Volume I</i>, Oxford University
    Press, 2018, pp. 189–218.'
  ista: 'Hausel T, Mellit A, Pei D. 2018.Mirror symmetry with branes by equivariant
    verlinde formulas. In: Geometry and Physics: Volume I. , 189–218.'
  mla: 'Hausel, Tamás, et al. “Mirror Symmetry with Branes by Equivariant Verlinde
    Formulas.” <i>Geometry and Physics: Volume I</i>, Oxford University Press, 2018,
    pp. 189–218, doi:<a href="https://doi.org/10.1093/oso/9780198802013.003.0009">10.1093/oso/9780198802013.003.0009</a>.'
  short: 'T. Hausel, A. Mellit, D. Pei, in:, Geometry and Physics: Volume I, Oxford
    University Press, 2018, pp. 189–218.'
date_created: 2019-06-06T12:42:01Z
date_published: 2018-01-01T00:00:00Z
date_updated: 2026-04-16T10:30:22Z
day: '01'
department:
- _id: TaHa
doi: 10.1093/oso/9780198802013.003.0009
language:
- iso: eng
month: '01'
oa_version: None
page: 189-218
publication: 'Geometry and Physics: Volume I'
publication_identifier:
  eisbn:
  - '9780191840500'
  isbn:
  - '9780198802013'
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mirror symmetry with branes by equivariant verlinde formulas
type: book_chapter
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2018'
...
---
_id: '438'
abstract:
- lang: eng
  text: The MazF toxin sequence-specifically cleaves single-stranded RNA upon various
    stressful conditions, and it is activated as a part of the mazEF toxin–antitoxin
    module in Escherichia coli. Although autoregulation of mazEF expression through
    the MazE antitoxin-dependent transcriptional repression has been biochemically
    characterized, less is known about post-transcriptional autoregulation, as well
    as how both of these autoregulatory features affect growth of single cells during
    conditions that promote MazF production. Here, we demonstrate post-transcriptional
    autoregulation of mazF expression dynamics by MazF cleaving its own transcript.
    Single-cell analyses of bacterial populations during ectopic MazF production indicated
    that two-level autoregulation of mazEF expression influences cell-to-cell growth
    rate heterogeneity. The increase in growth rate heterogeneity is governed by the
    MazE antitoxin, and tuned by the MazF-dependent mazF mRNA cleavage. Also, both
    autoregulatory features grant rapid exit from the stress caused by mazF overexpression.
    Time-lapse microscopy revealed that MazF-mediated cleavage of mazF mRNA leads
    to increased temporal variability in length of individual cells during ectopic
    mazF overexpression, as explained by a stochastic model indicating that mazEF
    mRNA cleavage underlies temporal fluctuations in MazF levels during stress.
article_processing_charge: Yes (in subscription journal)
author:
- first_name: Nela
  full_name: Nikolic, Nela
  id: 42D9CABC-F248-11E8-B48F-1D18A9856A87
  last_name: Nikolic
  orcid: 0000-0001-9068-6090
- first_name: Tobias
  full_name: Bergmiller, Tobias
  id: 2C471CFA-F248-11E8-B48F-1D18A9856A87
  last_name: Bergmiller
  orcid: 0000-0001-5396-4346
- first_name: Alexandra
  full_name: Vandervelde, Alexandra
  last_name: Vandervelde
- first_name: Tanino
  full_name: Albanese, Tanino
  last_name: Albanese
- first_name: Lendert
  full_name: Gelens, Lendert
  last_name: Gelens
- first_name: Isabella
  full_name: Moll, Isabella
  last_name: Moll
citation:
  ama: Nikolic N, Bergmiller T, Vandervelde A, Albanese T, Gelens L, Moll I. Autoregulation
    of mazEF expression underlies growth heterogeneity in bacterial populations. <i>Nucleic
    Acids Research</i>. 2018;46(6):2918-2931. doi:<a href="https://doi.org/10.1093/nar/gky079">10.1093/nar/gky079</a>
  apa: Nikolic, N., Bergmiller, T., Vandervelde, A., Albanese, T., Gelens, L., &#38;
    Moll, I. (2018). Autoregulation of mazEF expression underlies growth heterogeneity
    in bacterial populations. <i>Nucleic Acids Research</i>. Oxford University Press.
    <a href="https://doi.org/10.1093/nar/gky079">https://doi.org/10.1093/nar/gky079</a>
  chicago: Nikolic, Nela, Tobias Bergmiller, Alexandra Vandervelde, Tanino Albanese,
    Lendert Gelens, and Isabella Moll. “Autoregulation of MazEF Expression Underlies
    Growth Heterogeneity in Bacterial Populations.” <i>Nucleic Acids Research</i>.
    Oxford University Press, 2018. <a href="https://doi.org/10.1093/nar/gky079">https://doi.org/10.1093/nar/gky079</a>.
  ieee: N. Nikolic, T. Bergmiller, A. Vandervelde, T. Albanese, L. Gelens, and I.
    Moll, “Autoregulation of mazEF expression underlies growth heterogeneity in bacterial
    populations,” <i>Nucleic Acids Research</i>, vol. 46, no. 6. Oxford University
    Press, pp. 2918–2931, 2018.
  ista: Nikolic N, Bergmiller T, Vandervelde A, Albanese T, Gelens L, Moll I. 2018.
    Autoregulation of mazEF expression underlies growth heterogeneity in bacterial
    populations. Nucleic Acids Research. 46(6), 2918–2931.
  mla: Nikolic, Nela, et al. “Autoregulation of MazEF Expression Underlies Growth
    Heterogeneity in Bacterial Populations.” <i>Nucleic Acids Research</i>, vol. 46,
    no. 6, Oxford University Press, 2018, pp. 2918–31, doi:<a href="https://doi.org/10.1093/nar/gky079">10.1093/nar/gky079</a>.
  short: N. Nikolic, T. Bergmiller, A. Vandervelde, T. Albanese, L. Gelens, I. Moll,
    Nucleic Acids Research 46 (2018) 2918–2931.
corr_author: '1'
date_created: 2018-12-11T11:46:29Z
date_published: 2018-04-06T00:00:00Z
date_updated: 2025-04-15T06:28:24Z
day: '06'
ddc:
- '576'
department:
- _id: CaGu
doi: 10.1093/nar/gky079
external_id:
  isi:
  - '000429009500021'
file:
- access_level: open_access
  checksum: 3ff4f545c27e11a4cd20ccb30778793e
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:15:30Z
  date_updated: 2020-07-14T12:46:27Z
  file_id: '5151'
  file_name: IST-2018-971-v1+1_2018_Nikoloc_Autoregulation_of.pdf
  file_size: 5027978
  relation: main_file
file_date_updated: 2020-07-14T12:46:27Z
has_accepted_license: '1'
intvolume: '        46'
isi: 1
issue: '6'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 2918-2931
project:
- _id: 3AC91DDA-15DF-11EA-824D-93A3E7B544D1
  call_identifier: FWF
  name: FWF Open Access Fund
publication: Nucleic Acids Research
publication_status: published
publisher: Oxford University Press
pubrep_id: '971'
quality_controlled: '1'
related_material:
  record:
  - id: '5569'
    relation: popular_science
    status: public
scopus_import: '1'
status: public
title: Autoregulation of mazEF expression underlies growth heterogeneity in bacterial
  populations
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 46
year: '2018'
...
---
_id: '5569'
abstract:
- lang: eng
  text: "Nela Nikolic, Tobias Bergmiller, Alexandra Vandervelde, Tanino G. Albanese,
    Lendert Gelens, and Isabella Moll (2018)\r\n“Autoregulation of mazEF expression
    underlies growth heterogeneity in bacterial populations” Nucleic Acids Research,
    doi: 10.15479/AT:ISTA:74;\r\nmicroscopy experiments by Tobias Bergmiller; image
    and data analysis by Nela Nikolic."
article_processing_charge: No
author:
- first_name: Tobias
  full_name: Bergmiller, Tobias
  id: 2C471CFA-F248-11E8-B48F-1D18A9856A87
  last_name: Bergmiller
  orcid: 0000-0001-5396-4346
- first_name: Nela
  full_name: Nikolic, Nela
  id: 42D9CABC-F248-11E8-B48F-1D18A9856A87
  last_name: Nikolic
  orcid: 0000-0001-9068-6090
citation:
  ama: Bergmiller T, Nikolic N. Time-lapse microscopy data. 2018. doi:<a href="https://doi.org/10.15479/AT:ISTA:74">10.15479/AT:ISTA:74</a>
  apa: Bergmiller, T., &#38; Nikolic, N. (2018). Time-lapse microscopy data. Institute
    of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:74">https://doi.org/10.15479/AT:ISTA:74</a>
  chicago: Bergmiller, Tobias, and Nela Nikolic. “Time-Lapse Microscopy Data.” Institute
    of Science and Technology Austria, 2018. <a href="https://doi.org/10.15479/AT:ISTA:74">https://doi.org/10.15479/AT:ISTA:74</a>.
  ieee: T. Bergmiller and N. Nikolic, “Time-lapse microscopy data.” Institute of Science
    and Technology Austria, 2018.
  ista: Bergmiller T, Nikolic N. 2018. Time-lapse microscopy data, Institute of Science
    and Technology Austria, <a href="https://doi.org/10.15479/AT:ISTA:74">10.15479/AT:ISTA:74</a>.
  mla: Bergmiller, Tobias, and Nela Nikolic. <i>Time-Lapse Microscopy Data</i>. Institute
    of Science and Technology Austria, 2018, doi:<a href="https://doi.org/10.15479/AT:ISTA:74">10.15479/AT:ISTA:74</a>.
  short: T. Bergmiller, N. Nikolic, (2018).
datarep_id: '74'
date_created: 2018-12-12T12:31:35Z
date_published: 2018-02-07T00:00:00Z
date_updated: 2026-04-16T12:20:36Z
day: '07'
ddc:
- '579'
department:
- _id: CaGu
doi: 10.15479/AT:ISTA:74
file:
- access_level: open_access
  checksum: 61ebb92213cfffeba3ddbaff984b81af
  content_type: application/zip
  creator: system
  date_created: 2018-12-12T13:04:39Z
  date_updated: 2020-07-14T12:47:04Z
  file_id: '5637'
  file_name: IST-2018-74-v1+2_15-11-05.zip
  file_size: 3558703796
  relation: main_file
- access_level: open_access
  checksum: bf26649af310ef6892d68576515cde6d
  content_type: application/zip
  creator: system
  date_created: 2018-12-12T13:04:55Z
  date_updated: 2020-07-14T12:47:04Z
  file_id: '5638'
  file_name: IST-2018-74-v1+3_15-07-31.zip
  file_size: 1830422606
  relation: main_file
- access_level: open_access
  checksum: 8e46eedce06f22acb2be1a9b9d3f56bd
  content_type: application/zip
  creator: system
  date_created: 2018-12-12T13:05:11Z
  date_updated: 2020-07-14T12:47:04Z
  file_id: '5639'
  file_name: IST-2018-74-v1+4_Images_for_analysis.zip
  file_size: 2140849248
  relation: main_file
file_date_updated: 2020-07-14T12:47:04Z
has_accepted_license: '1'
keyword:
- microscopy
- microfluidics
license: https://creativecommons.org/publicdomain/zero/1.0/
month: '02'
oa: 1
oa_version: Published Version
publisher: Institute of Science and Technology Austria
publist_id: '7385'
related_material:
  record:
  - id: '438'
    relation: research_paper
    status: public
status: public
title: Time-lapse microscopy data
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2018'
...
---
_id: '6774'
abstract:
- lang: eng
  text: "A central problem of algebraic topology is to understand the homotopy groups
    \ \U0001D70B\U0001D451(\U0001D44B)  of a topological space X. For the computational
    version of the problem, it is well known that there is no algorithm to decide
    whether the fundamental group  \U0001D70B1(\U0001D44B)  of a given finite simplicial
    complex X is trivial. On the other hand, there are several algorithms that, given
    a finite simplicial complex X that is simply connected (i.e., with   \U0001D70B1(\U0001D44B)
    \ trivial), compute the higher homotopy group   \U0001D70B\U0001D451(\U0001D44B)
    \ for any given   \U0001D451≥2 . However, these algorithms come with a caveat:
    They compute the isomorphism type of   \U0001D70B\U0001D451(\U0001D44B) ,   \U0001D451≥2
    \ as an abstract finitely generated abelian group given by generators and relations,
    but they work with very implicit representations of the elements of   \U0001D70B\U0001D451(\U0001D44B)
    . Converting elements of this abstract group into explicit geometric maps from
    the d-dimensional sphere   \U0001D446\U0001D451  to X has been one of the main
    unsolved problems in the emerging field of computational homotopy theory. Here
    we present an algorithm that, given a simply connected space X, computes   \U0001D70B\U0001D451(\U0001D44B)
    \ and represents its elements as simplicial maps from a suitable triangulation
    of the d-sphere   \U0001D446\U0001D451  to X. For fixed d, the algorithm runs
    in time exponential in   size(\U0001D44B) , the number of simplices of X. Moreover,
    we prove that this is optimal: For every fixed   \U0001D451≥2 , we construct a
    family of simply connected spaces X such that for any simplicial map representing
    a generator of   \U0001D70B\U0001D451(\U0001D44B) , the size of the triangulation
    of   \U0001D446\U0001D451  on which the map is defined, is exponential in size(\U0001D44B)
    ."
article_type: original
author:
- first_name: Marek
  full_name: Filakovský, Marek
  id: 3E8AF77E-F248-11E8-B48F-1D18A9856A87
  last_name: Filakovský
- first_name: Peter
  full_name: Franek, Peter
  id: 473294AE-F248-11E8-B48F-1D18A9856A87
  last_name: Franek
  orcid: 0000-0001-8878-8397
- first_name: Uli
  full_name: Wagner, Uli
  id: 36690CA2-F248-11E8-B48F-1D18A9856A87
  last_name: Wagner
  orcid: 0000-0002-1494-0568
- first_name: Stephan Y
  full_name: Zhechev, Stephan Y
  id: 3AA52972-F248-11E8-B48F-1D18A9856A87
  last_name: Zhechev
citation:
  ama: Filakovský M, Franek P, Wagner U, Zhechev SY. Computing simplicial representatives
    of homotopy group elements. <i>Journal of Applied and Computational Topology</i>.
    2018;2(3-4):177-231. doi:<a href="https://doi.org/10.1007/s41468-018-0021-5">10.1007/s41468-018-0021-5</a>
  apa: Filakovský, M., Franek, P., Wagner, U., &#38; Zhechev, S. Y. (2018). Computing
    simplicial representatives of homotopy group elements. <i>Journal of Applied and
    Computational Topology</i>. Springer. <a href="https://doi.org/10.1007/s41468-018-0021-5">https://doi.org/10.1007/s41468-018-0021-5</a>
  chicago: Filakovský, Marek, Peter Franek, Uli Wagner, and Stephan Y Zhechev. “Computing
    Simplicial Representatives of Homotopy Group Elements.” <i>Journal of Applied
    and Computational Topology</i>. Springer, 2018. <a href="https://doi.org/10.1007/s41468-018-0021-5">https://doi.org/10.1007/s41468-018-0021-5</a>.
  ieee: M. Filakovský, P. Franek, U. Wagner, and S. Y. Zhechev, “Computing simplicial
    representatives of homotopy group elements,” <i>Journal of Applied and Computational
    Topology</i>, vol. 2, no. 3–4. Springer, pp. 177–231, 2018.
  ista: Filakovský M, Franek P, Wagner U, Zhechev SY. 2018. Computing simplicial representatives
    of homotopy group elements. Journal of Applied and Computational Topology. 2(3–4),
    177–231.
  mla: Filakovský, Marek, et al. “Computing Simplicial Representatives of Homotopy
    Group Elements.” <i>Journal of Applied and Computational Topology</i>, vol. 2,
    no. 3–4, Springer, 2018, pp. 177–231, doi:<a href="https://doi.org/10.1007/s41468-018-0021-5">10.1007/s41468-018-0021-5</a>.
  short: M. Filakovský, P. Franek, U. Wagner, S.Y. Zhechev, Journal of Applied and
    Computational Topology 2 (2018) 177–231.
corr_author: '1'
date_created: 2019-08-08T06:47:40Z
date_published: 2018-12-01T00:00:00Z
date_updated: 2026-04-08T13:56:01Z
day: '01'
ddc:
- '514'
department:
- _id: UlWa
doi: 10.1007/s41468-018-0021-5
file:
- access_level: open_access
  checksum: cf9e7fcd2a113dd4828774fc75cdb7e8
  content_type: application/pdf
  creator: dernst
  date_created: 2019-08-08T06:55:21Z
  date_updated: 2020-07-14T12:47:40Z
  file_id: '6775'
  file_name: 2018_JourAppliedComputTopology_Filakovsky.pdf
  file_size: 1056278
  relation: main_file
file_date_updated: 2020-07-14T12:47:40Z
has_accepted_license: '1'
intvolume: '         2'
issue: 3-4
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 177-231
project:
- _id: 25F8B9BC-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: M01980
  name: Robust Invariants of Nonlinear Systems
- _id: 3AC91DDA-15DF-11EA-824D-93A3E7B544D1
  call_identifier: FWF
  name: FWF Open Access Fund
publication: Journal of Applied and Computational Topology
publication_identifier:
  eissn:
  - 2367-1734
  issn:
  - 2367-1726
publication_status: published
publisher: Springer
quality_controlled: '1'
related_material:
  record:
  - id: '6681'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Computing simplicial representatives of homotopy group elements
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2
year: '2018'
...
---
OA_place: publisher
_id: '52'
abstract:
- lang: eng
  text: In this thesis we will discuss systems of point interacting fermions, their
    stability and other spectral properties. Whereas for bosons a point interacting
    system is always unstable this ques- tion is more subtle for a gas of two species
    of fermions. In particular the answer depends on the mass ratio between these
    two species. Most of this work will be focused on the N + M model which consists
    of two species of fermions with N, M particles respectively which interact via
    point interactions. We will introduce this model using a formal limit and discuss
    the N + 1 system in more detail. In particular, we will show that for mass ratios
    above a critical one, which does not depend on the particle number, the N + 1
    system is stable. In the context of this model we will prove rigorous versions
    of Tan relations which relate various quantities of the point-interacting model.
    By restricting the N + 1 system to a box we define a finite density model with
    point in- teractions. In the context of this system we will discuss the energy
    change when introducing a point-interacting impurity into a system of non-interacting
    fermions. We will see that this change in energy is bounded independently of the
    particle number and in particular the bound only depends on the density and the
    scattering length. As another special case of the N + M model we will show stability
    of the 2 + 2 model for mass ratios in an interval around one. Further we will
    investigate a different model of point interactions which was discussed before
    in the literature and which is, contrary to the N + M model, not given by a limiting
    procedure but is based on a Dirichlet form. We will show that this system behaves
    trivially in the thermodynamic limit, i.e. the free energy per particle is the
    same as the one of the non-interacting system.
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Thomas
  full_name: Moser, Thomas
  id: 2B5FC9A4-F248-11E8-B48F-1D18A9856A87
  last_name: Moser
citation:
  ama: Moser T. Point interactions in systems of fermions. 2018. doi:<a href="https://doi.org/10.15479/AT:ISTA:th_1043">10.15479/AT:ISTA:th_1043</a>
  apa: Moser, T. (2018). <i>Point interactions in systems of fermions</i>. Institute
    of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:th_1043">https://doi.org/10.15479/AT:ISTA:th_1043</a>
  chicago: Moser, Thomas. “Point Interactions in Systems of Fermions.” Institute of
    Science and Technology Austria, 2018. <a href="https://doi.org/10.15479/AT:ISTA:th_1043">https://doi.org/10.15479/AT:ISTA:th_1043</a>.
  ieee: T. Moser, “Point interactions in systems of fermions,” Institute of Science
    and Technology Austria, 2018.
  ista: Moser T. 2018. Point interactions in systems of fermions. Institute of Science
    and Technology Austria.
  mla: Moser, Thomas. <i>Point Interactions in Systems of Fermions</i>. Institute
    of Science and Technology Austria, 2018, doi:<a href="https://doi.org/10.15479/AT:ISTA:th_1043">10.15479/AT:ISTA:th_1043</a>.
  short: T. Moser, Point Interactions in Systems of Fermions, Institute of Science
    and Technology Austria, 2018.
corr_author: '1'
date_created: 2018-12-11T11:44:22Z
date_published: 2018-09-04T00:00:00Z
date_updated: 2026-04-16T12:20:40Z
day: '04'
ddc:
- '515'
- '530'
- '519'
degree_awarded: PhD
department:
- _id: RoSe
doi: 10.15479/AT:ISTA:th_1043
file:
- access_level: open_access
  checksum: fbd8c747d148b468a21213b7cf175225
  content_type: application/pdf
  creator: dernst
  date_created: 2019-04-09T07:45:38Z
  date_updated: 2020-07-14T12:46:37Z
  file_id: '6256'
  file_name: 2018_Thesis_Moser.pdf
  file_size: 851164
  relation: main_file
- access_level: closed
  checksum: c28e16ecfc1126d3ce324ec96493c01e
  content_type: application/zip
  creator: dernst
  date_created: 2019-04-09T07:45:38Z
  date_updated: 2020-07-14T12:46:37Z
  file_id: '6257'
  file_name: 2018_Thesis_Moser_Source.zip
  file_size: 1531516
  relation: source_file
file_date_updated: 2020-07-14T12:46:37Z
has_accepted_license: '1'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: '115'
project:
- _id: 25C878CE-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P27533_N27
  name: Structure of the Excitation Spectrum for Many-Body Quantum Systems
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '8002'
pubrep_id: '1043'
related_material:
  record:
  - id: '5856'
    relation: part_of_dissertation
    status: public
  - id: '741'
    relation: part_of_dissertation
    status: public
  - id: '1198'
    relation: part_of_dissertation
    status: public
  - id: '154'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Robert
  full_name: Seiringer, Robert
  id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
  last_name: Seiringer
  orcid: 0000-0002-6781-0521
title: Point interactions in systems of fermions
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2018'
...
---
_id: '154'
abstract:
- lang: eng
  text: We give a lower bound on the ground state energy of a system of two fermions
    of one species interacting with two fermions of another species via point interactions.
    We show that there is a critical mass ratio m2 ≈ 0.58 such that the system is
    stable, i.e., the energy is bounded from below, for m∈[m2,m2−1]. So far it was
    not known whether this 2 + 2 system exhibits a stable region at all or whether
    the formation of four-body bound states causes an unbounded spectrum for all mass
    ratios, similar to the Thomas effect. Our result gives further evidence for the
    stability of the more general N + M system.
acknowledgement: Open access funding provided by Austrian Science Fund (FWF).
article_number: '19'
article_processing_charge: No
article_type: original
author:
- first_name: Thomas
  full_name: Moser, Thomas
  id: 2B5FC9A4-F248-11E8-B48F-1D18A9856A87
  last_name: Moser
- first_name: Robert
  full_name: Seiringer, Robert
  id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
  last_name: Seiringer
  orcid: 0000-0002-6781-0521
citation:
  ama: Moser T, Seiringer R. Stability of the 2+2 fermionic system with point interactions.
    <i>Mathematical Physics Analysis and Geometry</i>. 2018;21(3). doi:<a href="https://doi.org/10.1007/s11040-018-9275-3">10.1007/s11040-018-9275-3</a>
  apa: Moser, T., &#38; Seiringer, R. (2018). Stability of the 2+2 fermionic system
    with point interactions. <i>Mathematical Physics Analysis and Geometry</i>. Springer.
    <a href="https://doi.org/10.1007/s11040-018-9275-3">https://doi.org/10.1007/s11040-018-9275-3</a>
  chicago: Moser, Thomas, and Robert Seiringer. “Stability of the 2+2 Fermionic System
    with Point Interactions.” <i>Mathematical Physics Analysis and Geometry</i>. Springer,
    2018. <a href="https://doi.org/10.1007/s11040-018-9275-3">https://doi.org/10.1007/s11040-018-9275-3</a>.
  ieee: T. Moser and R. Seiringer, “Stability of the 2+2 fermionic system with point
    interactions,” <i>Mathematical Physics Analysis and Geometry</i>, vol. 21, no.
    3. Springer, 2018.
  ista: Moser T, Seiringer R. 2018. Stability of the 2+2 fermionic system with point
    interactions. Mathematical Physics Analysis and Geometry. 21(3), 19.
  mla: Moser, Thomas, and Robert Seiringer. “Stability of the 2+2 Fermionic System
    with Point Interactions.” <i>Mathematical Physics Analysis and Geometry</i>, vol.
    21, no. 3, 19, Springer, 2018, doi:<a href="https://doi.org/10.1007/s11040-018-9275-3">10.1007/s11040-018-9275-3</a>.
  short: T. Moser, R. Seiringer, Mathematical Physics Analysis and Geometry 21 (2018).
date_created: 2018-12-11T11:44:55Z
date_published: 2018-09-01T00:00:00Z
date_updated: 2026-04-08T14:12:30Z
day: '01'
ddc:
- '530'
department:
- _id: RoSe
doi: 10.1007/s11040-018-9275-3
ec_funded: 1
external_id:
  isi:
  - '000439639700001'
file:
- access_level: open_access
  checksum: 411c4db5700d7297c9cd8ebc5dd29091
  content_type: application/pdf
  creator: dernst
  date_created: 2018-12-17T16:49:02Z
  date_updated: 2020-07-14T12:45:01Z
  file_id: '5729'
  file_name: 2018_MathPhysics_Moser.pdf
  file_size: 496973
  relation: main_file
file_date_updated: 2020-07-14T12:45:01Z
has_accepted_license: '1'
intvolume: '        21'
isi: 1
issue: '3'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
project:
- _id: 25C6DC12-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '694227'
  name: Analysis of quantum many-body systems
- _id: 25C878CE-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P27533_N27
  name: Structure of the Excitation Spectrum for Many-Body Quantum Systems
- _id: 3AC91DDA-15DF-11EA-824D-93A3E7B544D1
  call_identifier: FWF
  name: FWF Open Access Fund
publication: Mathematical Physics Analysis and Geometry
publication_identifier:
  eissn:
  - 1572-9656
  issn:
  - 1385-0172
publication_status: published
publisher: Springer
publist_id: '7767'
quality_controlled: '1'
related_material:
  record:
  - id: '52'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Stability of the 2+2 fermionic system with point interactions
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 21
year: '2018'
...
---
OA_place: repository
OA_type: green
_id: '203'
abstract:
- lang: eng
  text: Asymmetric auxin distribution is instrumental for the differential growth
    that causes organ bending on tropic stimuli and curvatures during plant development.
    Local differences in auxin concentrations are achieved mainly by polarized cellular
    distribution of PIN auxin transporters, but whether other mechanisms involving
    auxin homeostasis are also relevant for the formation of auxin gradients is not
    clear. Here we show that auxin methylation is required for asymmetric auxin distribution
    across the hypocotyl, particularly during its response to gravity. We found that
    loss-of-function mutants in Arabidopsis IAA CARBOXYL METHYLTRANSFERASE1 (IAMT1)
    prematurely unfold the apical hook, and that their hypocotyls are impaired in
    gravitropic reorientation. This defect is linked to an auxin-dependent increase
    in PIN gene expression, leading to an increased polar auxin transport and lack
    of asymmetric distribution of PIN3 in the iamt1 mutant. Gravitropic reorientation
    in the iamt1 mutant could be restored with either endodermis-specific expression
    of IAMT1 or partial inhibition of polar auxin transport, which also results in
    normal PIN gene expression levels. We propose that IAA methylation is necessary
    in gravity-sensing cells to restrict polar auxin transport within the range of
    auxin levels that allow for differential responses.
article_processing_charge: No
article_type: original
author:
- first_name: Mohamad
  full_name: Abbas, Mohamad
  id: 47E8FC1C-F248-11E8-B48F-1D18A9856A87
  last_name: Abbas
- first_name: García J
  full_name: Hernández, García J
  last_name: Hernández
- first_name: Stephan
  full_name: Pollmann, Stephan
  last_name: Pollmann
- first_name: Sophia L
  full_name: Samodelov, Sophia L
  last_name: Samodelov
- first_name: Martina
  full_name: Kolb, Martina
  last_name: Kolb
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Ulrich Z
  full_name: Hammes, Ulrich Z
  last_name: Hammes
- first_name: Matias D
  full_name: Zurbriggen, Matias D
  last_name: Zurbriggen
- first_name: Miguel
  full_name: Blázquez, Miguel
  last_name: Blázquez
- first_name: David
  full_name: Alabadí, David
  last_name: Alabadí
citation:
  ama: Abbas M, Hernández GJ, Pollmann S, et al. Auxin methylation is required for
    differential growth in Arabidopsis. <i>PNAS</i>. 2018;115(26):6864-6869. doi:<a
    href="https://doi.org/10.1073/pnas.1806565115">10.1073/pnas.1806565115</a>
  apa: Abbas, M., Hernández, G. J., Pollmann, S., Samodelov, S. L., Kolb, M., Friml,
    J., … Alabadí, D. (2018). Auxin methylation is required for differential growth
    in Arabidopsis. <i>PNAS</i>. National Academy of Sciences. <a href="https://doi.org/10.1073/pnas.1806565115">https://doi.org/10.1073/pnas.1806565115</a>
  chicago: Abbas, Mohamad, García J Hernández, Stephan Pollmann, Sophia L Samodelov,
    Martina Kolb, Jiří Friml, Ulrich Z Hammes, Matias D Zurbriggen, Miguel Blázquez,
    and David Alabadí. “Auxin Methylation Is Required for Differential Growth in Arabidopsis.”
    <i>PNAS</i>. National Academy of Sciences, 2018. <a href="https://doi.org/10.1073/pnas.1806565115">https://doi.org/10.1073/pnas.1806565115</a>.
  ieee: M. Abbas <i>et al.</i>, “Auxin methylation is required for differential growth
    in Arabidopsis,” <i>PNAS</i>, vol. 115, no. 26. National Academy of Sciences,
    pp. 6864–6869, 2018.
  ista: Abbas M, Hernández GJ, Pollmann S, Samodelov SL, Kolb M, Friml J, Hammes UZ,
    Zurbriggen MD, Blázquez M, Alabadí D. 2018. Auxin methylation is required for
    differential growth in Arabidopsis. PNAS. 115(26), 6864–6869.
  mla: Abbas, Mohamad, et al. “Auxin Methylation Is Required for Differential Growth
    in Arabidopsis.” <i>PNAS</i>, vol. 115, no. 26, National Academy of Sciences,
    2018, pp. 6864–69, doi:<a href="https://doi.org/10.1073/pnas.1806565115">10.1073/pnas.1806565115</a>.
  short: M. Abbas, G.J. Hernández, S. Pollmann, S.L. Samodelov, M. Kolb, J. Friml,
    U.Z. Hammes, M.D. Zurbriggen, M. Blázquez, D. Alabadí, PNAS 115 (2018) 6864–6869.
date_created: 2018-12-11T11:45:11Z
date_published: 2018-06-26T00:00:00Z
date_updated: 2026-04-28T08:29:26Z
day: '26'
department:
- _id: JiFr
doi: 10.1073/pnas.1806565115
ec_funded: 1
external_id:
  isi:
  - '000436245000096'
intvolume: '       115'
isi: 1
issue: '26'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://eprints.nottingham.ac.uk/52388/
month: '06'
oa: 1
oa_version: Submitted Version
page: 6864-6869
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '282300'
  name: Polarity and subcellular dynamics in plants
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '7710'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Auxin methylation is required for differential growth in Arabidopsis
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 115
year: '2018'
...
---
_id: '1064'
abstract:
- lang: eng
  text: 'In 1945, A.W. Goodman and R.E. Goodman proved the following conjecture by
    P. Erdős: Given a family of (round) disks of radii r1, … , rn in the plane, it
    is always possible to cover them by a disk of radius R= ∑ ri, provided they cannot
    be separated into two subfamilies by a straight line disjoint from the disks.
    In this note we show that essentially the same idea may work for different analogues
    and generalizations of their result. In particular, we prove the following: Given
    a family of positive homothetic copies of a fixed convex body K⊂ Rd with homothety
    coefficients τ1, … , τn> 0 , it is always possible to cover them by a translate
    of d+12(∑τi)K, provided they cannot be separated into two subfamilies by a hyperplane
    disjoint from the homothets.'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Arseniy
  full_name: Akopyan, Arseniy
  id: 430D2C90-F248-11E8-B48F-1D18A9856A87
  last_name: Akopyan
  orcid: 0000-0002-2548-617X
- first_name: Alexey
  full_name: Balitskiy, Alexey
  last_name: Balitskiy
- first_name: Mikhail
  full_name: Grigorev, Mikhail
  last_name: Grigorev
citation:
  ama: Akopyan A, Balitskiy A, Grigorev M. On the circle covering theorem by A.W.
    Goodman and R.E. Goodman. <i>Discrete &#38; Computational Geometry</i>. 2018;59(4):1001-1009.
    doi:<a href="https://doi.org/10.1007/s00454-017-9883-x">10.1007/s00454-017-9883-x</a>
  apa: Akopyan, A., Balitskiy, A., &#38; Grigorev, M. (2018). On the circle covering
    theorem by A.W. Goodman and R.E. Goodman. <i>Discrete &#38; Computational Geometry</i>.
    Springer. <a href="https://doi.org/10.1007/s00454-017-9883-x">https://doi.org/10.1007/s00454-017-9883-x</a>
  chicago: Akopyan, Arseniy, Alexey Balitskiy, and Mikhail Grigorev. “On the Circle
    Covering Theorem by A.W. Goodman and R.E. Goodman.” <i>Discrete &#38; Computational
    Geometry</i>. Springer, 2018. <a href="https://doi.org/10.1007/s00454-017-9883-x">https://doi.org/10.1007/s00454-017-9883-x</a>.
  ieee: A. Akopyan, A. Balitskiy, and M. Grigorev, “On the circle covering theorem
    by A.W. Goodman and R.E. Goodman,” <i>Discrete &#38; Computational Geometry</i>,
    vol. 59, no. 4. Springer, pp. 1001–1009, 2018.
  ista: Akopyan A, Balitskiy A, Grigorev M. 2018. On the circle covering theorem by
    A.W. Goodman and R.E. Goodman. Discrete &#38; Computational Geometry. 59(4), 1001–1009.
  mla: Akopyan, Arseniy, et al. “On the Circle Covering Theorem by A.W. Goodman and
    R.E. Goodman.” <i>Discrete &#38; Computational Geometry</i>, vol. 59, no. 4, Springer,
    2018, pp. 1001–09, doi:<a href="https://doi.org/10.1007/s00454-017-9883-x">10.1007/s00454-017-9883-x</a>.
  short: A. Akopyan, A. Balitskiy, M. Grigorev, Discrete &#38; Computational Geometry
    59 (2018) 1001–1009.
corr_author: '1'
date_created: 2018-12-11T11:49:57Z
date_published: 2018-06-01T00:00:00Z
date_updated: 2026-05-20T10:19:33Z
day: '01'
ddc:
- '516'
- '000'
department:
- _id: HeEd
doi: 10.1007/s00454-017-9883-x
ec_funded: 1
external_id:
  isi:
  - '000432205500011'
file:
- access_level: open_access
  content_type: application/pdf
  creator: dernst
  date_created: 2019-01-18T09:27:36Z
  date_updated: 2019-01-18T09:27:36Z
  file_id: '5844'
  file_name: 2018_DiscreteComp_Akopyan.pdf
  file_size: 482518
  relation: main_file
  success: 1
file_date_updated: 2019-01-18T09:27:36Z
has_accepted_license: '1'
intvolume: '        59'
isi: 1
issue: '4'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 1001-1009
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication: Discrete & Computational Geometry
publication_identifier:
  eissn:
  - 1432-0444
  issn:
  - 0179-5376
publication_status: published
publisher: Springer
publist_id: '6324'
quality_controlled: '1'
scopus_import: '1'
status: public
title: On the circle covering theorem by A.W. Goodman and R.E. Goodman
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 59
year: '2018'
...
---
_id: '542'
abstract:
- lang: eng
  text: The t-haplotype, a mouse meiotic driver found on chromosome 17, has been a
    model for autosomal segregation distortion for close to a century, but several
    questions remain regarding its biology and evolutionary history. A recently published
    set of population genomics resources for wild mice includes several individuals
    heterozygous for the t-haplotype, which we use to characterize this selfish element
    at the genomic and transcriptomic level. Our results show that large sections
    of the t-haplotype have been replaced by standard homologous sequences, possibly
    due to occasional events of recombination, and that this complicates the inference
    of its history. As expected for a long genomic segment of very low recombination,
    the t-haplotype carries an excess of fixed nonsynonymous mutations compared to
    the standard chromosome. This excess is stronger for regions that have not undergone
    recent recombination, suggesting that occasional gene flow between the t and the
    standard chromosome may provide a mechanism to regenerate coding sequences that
    have accumulated deleterious mutations. Finally, we find that t-complex genes
    with altered expression largely overlap with deleted or amplified regions, and
    that carrying a t-haplotype alters the testis expression of genes outside of the
    t-complex, providing new leads into the pathways involved in the biology of this
    segregation distorter.
article_processing_charge: No
article_type: original
author:
- first_name: Réka K
  full_name: Kelemen, Réka K
  id: 48D3F8DE-F248-11E8-B48F-1D18A9856A87
  last_name: Kelemen
  orcid: 0000-0002-8489-9281
- first_name: Beatriz
  full_name: Vicoso, Beatriz
  id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
  last_name: Vicoso
  orcid: 0000-0002-4579-8306
citation:
  ama: Kelemen RK, Vicoso B. Complex history and differentiation patterns of the t-haplotype,
    a mouse meiotic driver. <i>Genetics</i>. 2018;208(1):365-375. doi:<a href="https://doi.org/10.1534/genetics.117.300513">10.1534/genetics.117.300513</a>
  apa: Kelemen, R. K., &#38; Vicoso, B. (2018). Complex history and differentiation
    patterns of the t-haplotype, a mouse meiotic driver. <i>Genetics</i>. Genetics
    Society of America. <a href="https://doi.org/10.1534/genetics.117.300513">https://doi.org/10.1534/genetics.117.300513</a>
  chicago: Kelemen, Réka K, and Beatriz Vicoso. “Complex History and Differentiation
    Patterns of the T-Haplotype, a Mouse Meiotic Driver.” <i>Genetics</i>. Genetics
    Society of America, 2018. <a href="https://doi.org/10.1534/genetics.117.300513">https://doi.org/10.1534/genetics.117.300513</a>.
  ieee: R. K. Kelemen and B. Vicoso, “Complex history and differentiation patterns
    of the t-haplotype, a mouse meiotic driver,” <i>Genetics</i>, vol. 208, no. 1.
    Genetics Society of America, pp. 365–375, 2018.
  ista: Kelemen RK, Vicoso B. 2018. Complex history and differentiation patterns of
    the t-haplotype, a mouse meiotic driver. Genetics. 208(1), 365–375.
  mla: Kelemen, Réka K., and Beatriz Vicoso. “Complex History and Differentiation
    Patterns of the T-Haplotype, a Mouse Meiotic Driver.” <i>Genetics</i>, vol. 208,
    no. 1, Genetics Society of America, 2018, pp. 365–75, doi:<a href="https://doi.org/10.1534/genetics.117.300513">10.1534/genetics.117.300513</a>.
  short: R.K. Kelemen, B. Vicoso, Genetics 208 (2018) 365–375.
corr_author: '1'
date_created: 2018-12-11T11:47:04Z
date_published: 2018-01-01T00:00:00Z
date_updated: 2026-05-31T22:30:09Z
day: '01'
ddc:
- '576'
department:
- _id: BeVi
doi: 10.1534/genetics.117.300513
ec_funded: 1
external_id:
  isi:
  - '000419356300024'
file:
- access_level: open_access
  checksum: 2123845e7031a0cf043905be160f9e69
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:15:14Z
  date_updated: 2020-07-14T12:46:50Z
  file_id: '5132'
  file_name: IST-2018-1058-v1+1_365.full__1_.pdf
  file_size: 1311661
  relation: main_file
file_date_updated: 2020-07-14T12:46:50Z
has_accepted_license: '1'
intvolume: '       208'
isi: 1
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 365 - 375
project:
- _id: 250BDE62-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '715257'
  name: Prevalence and Influence of Sexual Antagonism on Genome Evolution
publication: Genetics
publication_status: published
publisher: Genetics Society of America
publist_id: '7274'
pubrep_id: '1058'
quality_controlled: '1'
related_material:
  record:
  - id: '5571'
    relation: popular_science
    status: public
  - id: '5572'
    relation: popular_science
    status: public
  - id: '17119'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Complex history and differentiation patterns of the t-haplotype, a mouse meiotic
  driver
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 208
year: '2018'
...
