---
_id: '5805'
abstract:
- lang: eng
text: Discretization of sphere in the integer space follows a particular discretization
scheme, which, in principle, conforms to some topological model. This eventually
gives rise to interesting topological properties of a discrete spherical surface,
which need to be investigated for its analytical characterization. This paper
presents some novel results on the local topological properties of the naive model
of discrete sphere. They follow from the bijection of each quadraginta octant
of naive sphere with its projection map called f -map on the corresponding functional
plane and from the characterization of certain jumps in the f-map. As an application,
we have shown how these properties can be used in designing an efficient reconstruction
algorithm for a naive spherical surface from an input voxel set when it is sparse
or noisy.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Nabhasmita
full_name: Sen, Nabhasmita
last_name: Sen
- first_name: Ranita
full_name: Biswas, Ranita
id: 3C2B033E-F248-11E8-B48F-1D18A9856A87
last_name: Biswas
orcid: 0000-0002-5372-7890
- first_name: Partha
full_name: Bhowmick, Partha
last_name: Bhowmick
citation:
ama: 'Sen N, Biswas R, Bhowmick P. On some local topological properties of naive
discrete sphere. In: Computational Topology in Image Context. Vol 9667.
Cham: Springer Nature; 2016:253-264. doi:10.1007/978-3-319-39441-1_23'
apa: 'Sen, N., Biswas, R., & Bhowmick, P. (2016). On some local topological
properties of naive discrete sphere. In Computational Topology in Image Context
(Vol. 9667, pp. 253–264). Cham: Springer Nature. https://doi.org/10.1007/978-3-319-39441-1_23'
chicago: 'Sen, Nabhasmita, Ranita Biswas, and Partha Bhowmick. “On Some Local Topological
Properties of Naive Discrete Sphere.” In Computational Topology in Image Context,
9667:253–64. Cham: Springer Nature, 2016. https://doi.org/10.1007/978-3-319-39441-1_23.'
ieee: 'N. Sen, R. Biswas, and P. Bhowmick, “On some local topological properties
of naive discrete sphere,” in Computational Topology in Image Context,
vol. 9667, Cham: Springer Nature, 2016, pp. 253–264.'
ista: 'Sen N, Biswas R, Bhowmick P. 2016.On some local topological properties of
naive discrete sphere. In: Computational Topology in Image Context. LNCS, vol.
9667, 253–264.'
mla: Sen, Nabhasmita, et al. “On Some Local Topological Properties of Naive Discrete
Sphere.” Computational Topology in Image Context, vol. 9667, Springer Nature,
2016, pp. 253–64, doi:10.1007/978-3-319-39441-1_23.
short: N. Sen, R. Biswas, P. Bhowmick, in:, Computational Topology in Image Context,
Springer Nature, Cham, 2016, pp. 253–264.
conference:
end_date: 2016-06-17
location: Marseille, France
name: 'CTIC: Computational Topology in Image Context'
start_date: 2016-06-15
date_created: 2019-01-08T20:44:24Z
date_published: 2016-06-02T00:00:00Z
date_updated: 2022-01-28T08:01:22Z
day: '02'
department:
- _id: HeEd
doi: 10.1007/978-3-319-39441-1_23
extern: '1'
intvolume: ' 9667'
language:
- iso: eng
month: '06'
oa_version: None
page: 253-264
place: Cham
publication: Computational Topology in Image Context
publication_identifier:
eisbn:
- 978-3-319-39441-1
eissn:
- 1611-3349
isbn:
- 978-3-319-39440-4
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: On some local topological properties of naive discrete sphere
type: book_chapter
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 9667
year: '2016'
...
---
_id: '5806'
abstract:
- lang: eng
text: Although the concept of functional plane for naive plane is studied and reported
in the literature in great detail, no similar study is yet found for naive sphere.
This article exposes the first study in this line, opening up further prospects
of analyzing the topological properties of sphere in the discrete space. We show
that each quadraginta octant Q of a naive sphere forms a bijection with its projected
pixel set on a unique coordinate plane, which thereby serves as the functional
plane of Q, and hence gives rise to merely mono-jumps during back projection.
The other two coordinate planes serve as para-functional and dia-functional planes
for Q, as the former is ‘mono-jumping’ but not bijective, whereas the latter holds
neither of the two. Owing to this, the quadraginta octants form symmetry groups
and subgroups with equivalent jump conditions. We also show a potential application
in generating a special class of discrete 3D circles based on back projection
and jump bridging by Steiner voxels. A circle in this class possesses 4-symmetry,
uniqueness, and bounded distance from the underlying real sphere and real plane.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Ranita
full_name: Biswas, Ranita
id: 3C2B033E-F248-11E8-B48F-1D18A9856A87
last_name: Biswas
orcid: 0000-0002-5372-7890
- first_name: Partha
full_name: Bhowmick, Partha
last_name: Bhowmick
citation:
ama: 'Biswas R, Bhowmick P. On functionality of quadraginta octants of naive sphere
with application to circle drawing. In: Discrete Geometry for Computer Imagery.
Vol 9647. Cham: Springer Nature; 2016:256-267. doi:10.1007/978-3-319-32360-2_20'
apa: 'Biswas, R., & Bhowmick, P. (2016). On functionality of quadraginta octants
of naive sphere with application to circle drawing. In Discrete Geometry for
Computer Imagery (Vol. 9647, pp. 256–267). Cham: Springer Nature. https://doi.org/10.1007/978-3-319-32360-2_20'
chicago: 'Biswas, Ranita, and Partha Bhowmick. “On Functionality of Quadraginta
Octants of Naive Sphere with Application to Circle Drawing.” In Discrete Geometry
for Computer Imagery, 9647:256–67. Cham: Springer Nature, 2016. https://doi.org/10.1007/978-3-319-32360-2_20.'
ieee: R. Biswas and P. Bhowmick, “On functionality of quadraginta octants of naive
sphere with application to circle drawing,” in Discrete Geometry for Computer
Imagery, Nantes, France, 2016, vol. 9647, pp. 256–267.
ista: 'Biswas R, Bhowmick P. 2016. On functionality of quadraginta octants of naive
sphere with application to circle drawing. Discrete Geometry for Computer Imagery.
DGCI: International Conference on Discrete Geometry for Computer Imagery, LNCS,
vol. 9647, 256–267.'
mla: Biswas, Ranita, and Partha Bhowmick. “On Functionality of Quadraginta Octants
of Naive Sphere with Application to Circle Drawing.” Discrete Geometry for
Computer Imagery, vol. 9647, Springer Nature, 2016, pp. 256–67, doi:10.1007/978-3-319-32360-2_20.
short: R. Biswas, P. Bhowmick, in:, Discrete Geometry for Computer Imagery, Springer
Nature, Cham, 2016, pp. 256–267.
conference:
end_date: 2016-04-20
location: Nantes, France
name: 'DGCI: International Conference on Discrete Geometry for Computer Imagery'
start_date: 2016-04-18
date_created: 2019-01-08T20:44:37Z
date_published: 2016-04-09T00:00:00Z
date_updated: 2022-01-28T08:10:11Z
day: '09'
department:
- _id: HeEd
doi: 10.1007/978-3-319-32360-2_20
extern: '1'
intvolume: ' 9647'
language:
- iso: eng
month: '04'
oa_version: None
page: 256-267
place: Cham
publication: Discrete Geometry for Computer Imagery
publication_identifier:
eisbn:
- 978-3-319-32360-2
isbn:
- 978-3-319-32359-6
issn:
- 0302-9743
- 1611-3349
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: On functionality of quadraginta octants of naive sphere with application to
circle drawing
type: conference
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 9647
year: '2016'
...
---
_id: '5809'
abstract:
- lang: eng
text: A discrete spherical circle is a topologically well-connected 3D circle in
the integer space, which belongs to a discrete sphere as well as a discrete plane.
It is one of the most important 3D geometric primitives, but has not possibly
yet been studied up to its merit. This paper is a maiden exposition of some of
its elementary properties, which indicates a sense of its profound theoretical
prospects in the framework of digital geometry. We have shown how different types
of discretization can lead to forbidden and admissible classes, when one attempts
to define the discretization of a spherical circle in terms of intersection between
a discrete sphere and a discrete plane. Several fundamental theoretical results
have been presented, the algorithm for construction of discrete spherical circles
has been discussed, and some test results have been furnished to demonstrate its
practicality and usefulness.
article_processing_charge: No
author:
- first_name: Ranita
full_name: Biswas, Ranita
id: 3C2B033E-F248-11E8-B48F-1D18A9856A87
last_name: Biswas
orcid: 0000-0002-5372-7890
- first_name: Partha
full_name: Bhowmick, Partha
last_name: Bhowmick
- first_name: Valentin E.
full_name: Brimkov, Valentin E.
last_name: Brimkov
citation:
ama: 'Biswas R, Bhowmick P, Brimkov VE. On the connectivity and smoothness of discrete
spherical circles. In: Combinatorial Image Analysis. Vol 9448. Cham: Springer
Nature; 2016:86-100. doi:10.1007/978-3-319-26145-4_7'
apa: 'Biswas, R., Bhowmick, P., & Brimkov, V. E. (2016). On the connectivity
and smoothness of discrete spherical circles. In Combinatorial image analysis
(Vol. 9448, pp. 86–100). Cham: Springer Nature. https://doi.org/10.1007/978-3-319-26145-4_7'
chicago: 'Biswas, Ranita, Partha Bhowmick, and Valentin E. Brimkov. “On the Connectivity
and Smoothness of Discrete Spherical Circles.” In Combinatorial Image Analysis,
9448:86–100. Cham: Springer Nature, 2016. https://doi.org/10.1007/978-3-319-26145-4_7.'
ieee: 'R. Biswas, P. Bhowmick, and V. E. Brimkov, “On the connectivity and smoothness
of discrete spherical circles,” in Combinatorial image analysis, vol. 9448,
Cham: Springer Nature, 2016, pp. 86–100.'
ista: 'Biswas R, Bhowmick P, Brimkov VE. 2016.On the connectivity and smoothness
of discrete spherical circles. In: Combinatorial image analysis. vol. 9448, 86–100.'
mla: Biswas, Ranita, et al. “On the Connectivity and Smoothness of Discrete Spherical
Circles.” Combinatorial Image Analysis, vol. 9448, Springer Nature, 2016,
pp. 86–100, doi:10.1007/978-3-319-26145-4_7.
short: R. Biswas, P. Bhowmick, V.E. Brimkov, in:, Combinatorial Image Analysis,
Springer Nature, Cham, 2016, pp. 86–100.
conference:
end_date: 2015-11-27
location: Kolkata, India
name: 'IWCIA: International Workshop on Combinatorial Image Analysis'
start_date: 2015-11-24
date_created: 2019-01-08T20:45:19Z
date_published: 2016-01-06T00:00:00Z
date_updated: 2022-01-28T08:13:03Z
day: '06'
department:
- _id: HeEd
doi: 10.1007/978-3-319-26145-4_7
extern: '1'
intvolume: ' 9448'
language:
- iso: eng
month: '01'
oa_version: None
page: 86-100
place: Cham
publication: Combinatorial image analysis
publication_identifier:
eisbn:
- 978-3-319-26145-4
eissn:
- 1611-3349
isbn:
- 978-3-319-26144-7
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: On the connectivity and smoothness of discrete spherical circles
type: book_chapter
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 9448
year: '2016'
...
---
_id: '9862'
article_processing_charge: No
author:
- first_name: Camille
full_name: Roux, Camille
last_name: Roux
- first_name: Christelle
full_name: Fraisse, Christelle
id: 32DF5794-F248-11E8-B48F-1D18A9856A87
last_name: Fraisse
orcid: 0000-0001-8441-5075
- first_name: Jonathan
full_name: Romiguier, Jonathan
last_name: Romiguier
- first_name: Youann
full_name: Anciaux, Youann
last_name: Anciaux
- first_name: Nicolas
full_name: Galtier, Nicolas
last_name: Galtier
- first_name: Nicolas
full_name: Bierne, Nicolas
last_name: Bierne
citation:
ama: Roux C, Fraisse C, Romiguier J, Anciaux Y, Galtier N, Bierne N. Simulation
study to test the robustness of ABC in face of recent times of divergence. 2016.
doi:10.1371/journal.pbio.2000234.s016
apa: Roux, C., Fraisse, C., Romiguier, J., Anciaux, Y., Galtier, N., & Bierne,
N. (2016). Simulation study to test the robustness of ABC in face of recent times
of divergence. Public Library of Science. https://doi.org/10.1371/journal.pbio.2000234.s016
chicago: Roux, Camille, Christelle Fraisse, Jonathan Romiguier, Youann Anciaux,
Nicolas Galtier, and Nicolas Bierne. “Simulation Study to Test the Robustness
of ABC in Face of Recent Times of Divergence.” Public Library of Science, 2016.
https://doi.org/10.1371/journal.pbio.2000234.s016.
ieee: C. Roux, C. Fraisse, J. Romiguier, Y. Anciaux, N. Galtier, and N. Bierne,
“Simulation study to test the robustness of ABC in face of recent times of divergence.”
Public Library of Science, 2016.
ista: Roux C, Fraisse C, Romiguier J, Anciaux Y, Galtier N, Bierne N. 2016. Simulation
study to test the robustness of ABC in face of recent times of divergence, Public
Library of Science, 10.1371/journal.pbio.2000234.s016.
mla: Roux, Camille, et al. Simulation Study to Test the Robustness of ABC in
Face of Recent Times of Divergence. Public Library of Science, 2016, doi:10.1371/journal.pbio.2000234.s016.
short: C. Roux, C. Fraisse, J. Romiguier, Y. Anciaux, N. Galtier, N. Bierne, (2016).
date_created: 2021-08-10T08:20:17Z
date_updated: 2025-09-22T09:55:08Z
day: '27'
department:
- _id: BeVi
- _id: NiBa
doi: 10.1371/journal.pbio.2000234.s016
month: '12'
oa_version: Published Version
publisher: Public Library of Science
related_material:
record:
- id: '1158'
relation: used_in_publication
status: public
status: public
title: Simulation study to test the robustness of ABC in face of recent times of divergence
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2016'
...
---
_id: '9863'
article_processing_charge: No
author:
- first_name: Camille
full_name: Roux, Camille
last_name: Roux
- first_name: Christelle
full_name: Fraisse, Christelle
id: 32DF5794-F248-11E8-B48F-1D18A9856A87
last_name: Fraisse
orcid: 0000-0001-8441-5075
- first_name: Jonathan
full_name: Romiguier, Jonathan
last_name: Romiguier
- first_name: Youann
full_name: Anciaux, Youann
last_name: Anciaux
- first_name: Nicolas
full_name: Galtier, Nicolas
last_name: Galtier
- first_name: Nicolas
full_name: Bierne, Nicolas
last_name: Bierne
citation:
ama: Roux C, Fraisse C, Romiguier J, Anciaux Y, Galtier N, Bierne N. Accessions
of surveyed individuals, geographic locations and summary statistics. 2016. doi:10.1371/journal.pbio.2000234.s017
apa: Roux, C., Fraisse, C., Romiguier, J., Anciaux, Y., Galtier, N., & Bierne,
N. (2016). Accessions of surveyed individuals, geographic locations and summary
statistics. Public Library of Science. https://doi.org/10.1371/journal.pbio.2000234.s017
chicago: Roux, Camille, Christelle Fraisse, Jonathan Romiguier, Youann Anciaux,
Nicolas Galtier, and Nicolas Bierne. “Accessions of Surveyed Individuals, Geographic
Locations and Summary Statistics.” Public Library of Science, 2016. https://doi.org/10.1371/journal.pbio.2000234.s017.
ieee: C. Roux, C. Fraisse, J. Romiguier, Y. Anciaux, N. Galtier, and N. Bierne,
“Accessions of surveyed individuals, geographic locations and summary statistics.”
Public Library of Science, 2016.
ista: Roux C, Fraisse C, Romiguier J, Anciaux Y, Galtier N, Bierne N. 2016. Accessions
of surveyed individuals, geographic locations and summary statistics, Public Library
of Science, 10.1371/journal.pbio.2000234.s017.
mla: Roux, Camille, et al. Accessions of Surveyed Individuals, Geographic Locations
and Summary Statistics. Public Library of Science, 2016, doi:10.1371/journal.pbio.2000234.s017.
short: C. Roux, C. Fraisse, J. Romiguier, Y. Anciaux, N. Galtier, N. Bierne, (2016).
date_created: 2021-08-10T08:22:52Z
date_updated: 2025-09-22T09:55:09Z
day: '27'
department:
- _id: BeVi
- _id: NiBa
doi: 10.1371/journal.pbio.2000234.s017
month: '12'
oa_version: Published Version
publisher: Public Library of Science
related_material:
record:
- id: '1158'
relation: used_in_publication
status: public
status: public
title: Accessions of surveyed individuals, geographic locations and summary statistics
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2016'
...
---
_id: '9864'
abstract:
- lang: eng
text: Viral capsids are structurally constrained by interactions among the amino
acids (AAs) of their constituent proteins. Therefore, epistasis is expected to
evolve among physically interacting sites and to influence the rates of substitution.
To study the evolution of epistasis, we focused on the major structural protein
of the ϕX174 phage family by, first, reconstructing the ancestral protein sequences
of 18 species using a Bayesian statistical framework. The inferred ancestral reconstruction
differed at eight AAs, for a total of 256 possible ancestral haplotypes. For each
ancestral haplotype and the extant species, we estimated, in silico, the distribution
of free energies and epistasis of the capsid structure. We found that free energy
has not significantly increased but epistasis has. We decomposed epistasis up
to fifth order and found that higher-order epistasis sometimes compensates pairwise
interactions making the free energy seem additive. The dN/dS ratio is low, suggesting
strong purifying selection, and that structure is under stabilizing selection.
We synthesized phages carrying ancestral haplotypes of the coat protein gene and
measured their fitness experimentally. Our findings indicate that stabilizing
mutations can have higher fitness, and that fitness optima do not necessarily
coincide with energy minima.
article_processing_charge: No
author:
- first_name: Rodrigo A
full_name: Fernandes Redondo, Rodrigo A
id: 409D5C96-F248-11E8-B48F-1D18A9856A87
last_name: Fernandes Redondo
orcid: 0000-0002-5837-2793
- first_name: Harold
full_name: de Vladar, Harold
id: 2A181218-F248-11E8-B48F-1D18A9856A87
last_name: de Vladar
orcid: 0000-0002-5985-7653
- first_name: Tomasz
full_name: Włodarski, Tomasz
last_name: Włodarski
- first_name: Jonathan P
full_name: Bollback, Jonathan P
id: 2C6FA9CC-F248-11E8-B48F-1D18A9856A87
last_name: Bollback
orcid: 0000-0002-4624-4612
citation:
ama: Fernandes Redondo RA, de Vladar H, Włodarski T, Bollback JP. Data from evolutionary
interplay between structure, energy and epistasis in the coat protein of the ϕX174
phage family. 2016. doi:10.6084/m9.figshare.4315652.v1
apa: Fernandes Redondo, R. A., de Vladar, H., Włodarski, T., & Bollback, J.
P. (2016). Data from evolutionary interplay between structure, energy and epistasis
in the coat protein of the ϕX174 phage family. The Royal Society. https://doi.org/10.6084/m9.figshare.4315652.v1
chicago: Fernandes Redondo, Rodrigo A, Harold de Vladar, Tomasz Włodarski, and Jonathan
P Bollback. “Data from Evolutionary Interplay between Structure, Energy and Epistasis
in the Coat Protein of the ΦX174 Phage Family.” The Royal Society, 2016. https://doi.org/10.6084/m9.figshare.4315652.v1.
ieee: R. A. Fernandes Redondo, H. de Vladar, T. Włodarski, and J. P. Bollback, “Data
from evolutionary interplay between structure, energy and epistasis in the coat
protein of the ϕX174 phage family.” The Royal Society, 2016.
ista: Fernandes Redondo RA, de Vladar H, Włodarski T, Bollback JP. 2016. Data from
evolutionary interplay between structure, energy and epistasis in the coat protein
of the ϕX174 phage family, The Royal Society, 10.6084/m9.figshare.4315652.v1.
mla: Fernandes Redondo, Rodrigo A., et al. Data from Evolutionary Interplay between
Structure, Energy and Epistasis in the Coat Protein of the ΦX174 Phage Family.
The Royal Society, 2016, doi:10.6084/m9.figshare.4315652.v1.
short: R.A. Fernandes Redondo, H. de Vladar, T. Włodarski, J.P. Bollback, (2016).
date_created: 2021-08-10T08:29:47Z
date_published: 2016-12-14T00:00:00Z
date_updated: 2025-07-10T11:49:59Z
day: '14'
department:
- _id: NiBa
- _id: JoBo
doi: 10.6084/m9.figshare.4315652.v1
main_file_link:
- open_access: '1'
url: https://doi.org/10.6084/m9.figshare.4315652.v1
month: '12'
oa: 1
oa_version: Published Version
publisher: The Royal Society
related_material:
record:
- id: '1077'
relation: used_in_publication
status: public
status: public
title: Data from evolutionary interplay between structure, energy and epistasis in
the coat protein of the ϕX174 phage family
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2016'
...
---
_id: '9866'
article_processing_charge: No
author:
- first_name: Marcin P
full_name: Zagórski, Marcin P
id: 343DA0DC-F248-11E8-B48F-1D18A9856A87
last_name: Zagórski
orcid: 0000-0001-7896-7762
- first_name: Zdzisław
full_name: Burda, Zdzisław
last_name: Burda
- first_name: Bartłomiej
full_name: Wacław, Bartłomiej
last_name: Wacław
citation:
ama: Zagórski MP, Burda Z, Wacław B. ZIP-archived directory containing all data
and computer programs. 2016. doi:10.1371/journal.pcbi.1005218.s009
apa: Zagórski, M. P., Burda, Z., & Wacław, B. (2016). ZIP-archived directory
containing all data and computer programs. Public Library of Science. https://doi.org/10.1371/journal.pcbi.1005218.s009
chicago: Zagórski, Marcin P, Zdzisław Burda, and Bartłomiej Wacław. “ZIP-Archived
Directory Containing All Data and Computer Programs.” Public Library of Science,
2016. https://doi.org/10.1371/journal.pcbi.1005218.s009.
ieee: M. P. Zagórski, Z. Burda, and B. Wacław, “ZIP-archived directory containing
all data and computer programs.” Public Library of Science, 2016.
ista: Zagórski MP, Burda Z, Wacław B. 2016. ZIP-archived directory containing all
data and computer programs, Public Library of Science, 10.1371/journal.pcbi.1005218.s009.
mla: Zagórski, Marcin P., et al. ZIP-Archived Directory Containing All Data and
Computer Programs. Public Library of Science, 2016, doi:10.1371/journal.pcbi.1005218.s009.
short: M.P. Zagórski, Z. Burda, B. Wacław, (2016).
date_created: 2021-08-10T08:37:20Z
date_published: 2016-12-09T00:00:00Z
date_updated: 2025-09-22T09:53:16Z
day: '09'
department:
- _id: AnKi
doi: 10.1371/journal.pcbi.1005218.s009
month: '12'
oa_version: Published Version
publisher: Public Library of Science
related_material:
record:
- id: '1167'
relation: used_in_publication
status: public
status: public
title: ZIP-archived directory containing all data and computer programs
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2016'
...
---
_id: '9867'
abstract:
- lang: eng
text: In the beginning of our experiment, subjects were asked to read a few pages
on their computer screens that would explain the rules of the subsequent game.
Here, we provide these instructions, translated from German.
article_processing_charge: No
author:
- first_name: Christian
full_name: Hilbe, Christian
id: 2FDF8F3C-F248-11E8-B48F-1D18A9856A87
last_name: Hilbe
orcid: 0000-0001-5116-955X
- first_name: Kristin
full_name: Hagel, Kristin
last_name: Hagel
- first_name: Manfred
full_name: Milinski, Manfred
last_name: Milinski
citation:
ama: Hilbe C, Hagel K, Milinski M. Experimental game instructions. 2016. doi:10.1371/journal.pone.0163867.s008
apa: Hilbe, C., Hagel, K., & Milinski, M. (2016). Experimental game instructions.
Public Library of Science. https://doi.org/10.1371/journal.pone.0163867.s008
chicago: Hilbe, Christian, Kristin Hagel, and Manfred Milinski. “Experimental Game
Instructions.” Public Library of Science, 2016. https://doi.org/10.1371/journal.pone.0163867.s008.
ieee: C. Hilbe, K. Hagel, and M. Milinski, “Experimental game instructions.” Public
Library of Science, 2016.
ista: Hilbe C, Hagel K, Milinski M. 2016. Experimental game instructions, Public
Library of Science, 10.1371/journal.pone.0163867.s008.
mla: Hilbe, Christian, et al. Experimental Game Instructions. Public Library
of Science, 2016, doi:10.1371/journal.pone.0163867.s008.
short: C. Hilbe, K. Hagel, M. Milinski, (2016).
date_created: 2021-08-10T08:42:00Z
date_updated: 2025-09-22T08:27:00Z
day: '04'
department:
- _id: KrCh
doi: 10.1371/journal.pone.0163867.s008
month: '10'
oa_version: Published Version
publisher: Public Library of Science
related_material:
record:
- id: '1322'
relation: used_in_publication
status: public
status: public
title: Experimental game instructions
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2016'
...
---
_id: '9868'
abstract:
- lang: eng
text: The raw data file containing the experimental decisions of all our study subjects.
article_processing_charge: No
author:
- first_name: Christian
full_name: Hilbe, Christian
id: 2FDF8F3C-F248-11E8-B48F-1D18A9856A87
last_name: Hilbe
orcid: 0000-0001-5116-955X
- first_name: Kristin
full_name: Hagel, Kristin
last_name: Hagel
- first_name: Manfred
full_name: Milinski, Manfred
last_name: Milinski
citation:
ama: Hilbe C, Hagel K, Milinski M. Experimental data. 2016. doi:10.1371/journal.pone.0163867.s009
apa: Hilbe, C., Hagel, K., & Milinski, M. (2016). Experimental data. Public
Library of Science. https://doi.org/10.1371/journal.pone.0163867.s009
chicago: Hilbe, Christian, Kristin Hagel, and Manfred Milinski. “Experimental Data.”
Public Library of Science, 2016. https://doi.org/10.1371/journal.pone.0163867.s009.
ieee: C. Hilbe, K. Hagel, and M. Milinski, “Experimental data.” Public Library of
Science, 2016.
ista: Hilbe C, Hagel K, Milinski M. 2016. Experimental data, Public Library of Science,
10.1371/journal.pone.0163867.s009.
mla: Hilbe, Christian, et al. Experimental Data. Public Library of Science,
2016, doi:10.1371/journal.pone.0163867.s009.
short: C. Hilbe, K. Hagel, M. Milinski, (2016).
date_created: 2021-08-10T08:45:00Z
date_published: 2016-10-04T00:00:00Z
date_updated: 2025-09-22T08:27:00Z
day: '04'
department:
- _id: KrCh
doi: 10.1371/journal.pone.0163867.s009
month: '10'
oa_version: Published Version
publisher: Public Library of Science
related_material:
record:
- id: '1322'
relation: used_in_publication
status: public
status: public
title: Experimental data
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2016'
...
---
_id: '9869'
abstract:
- lang: eng
text: A lower bound on the error of a positional estimator with limited positional
information is derived.
article_processing_charge: No
author:
- first_name: Patrick
full_name: Hillenbrand, Patrick
last_name: Hillenbrand
- first_name: Ulrich
full_name: Gerland, Ulrich
last_name: Gerland
- first_name: Gašper
full_name: Tkačik, Gašper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkačik
orcid: 0000-0002-6699-1455
citation:
ama: Hillenbrand P, Gerland U, Tkačik G. Error bound on an estimator of position.
2016. doi:10.1371/journal.pone.0163628.s001
apa: Hillenbrand, P., Gerland, U., & Tkačik, G. (2016). Error bound on an estimator
of position. Public Library of Science. https://doi.org/10.1371/journal.pone.0163628.s001
chicago: Hillenbrand, Patrick, Ulrich Gerland, and Gašper Tkačik. “Error Bound on
an Estimator of Position.” Public Library of Science, 2016. https://doi.org/10.1371/journal.pone.0163628.s001.
ieee: P. Hillenbrand, U. Gerland, and G. Tkačik, “Error bound on an estimator of
position.” Public Library of Science, 2016.
ista: Hillenbrand P, Gerland U, Tkačik G. 2016. Error bound on an estimator of position,
Public Library of Science, 10.1371/journal.pone.0163628.s001.
mla: Hillenbrand, Patrick, et al. Error Bound on an Estimator of Position.
Public Library of Science, 2016, doi:10.1371/journal.pone.0163628.s001.
short: P. Hillenbrand, U. Gerland, G. Tkačik, (2016).
date_created: 2021-08-10T08:53:48Z
date_published: 2016-09-27T00:00:00Z
date_updated: 2025-09-22T08:46:14Z
day: '27'
department:
- _id: GaTk
doi: 10.1371/journal.pone.0163628.s001
month: '09'
oa_version: Published Version
publisher: Public Library of Science
related_material:
record:
- id: '1270'
relation: used_in_publication
status: public
status: public
title: Error bound on an estimator of position
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2016'
...
---
_id: '9870'
abstract:
- lang: eng
text: The effect of noise in the input field on an Ising model is approximated.
Furthermore, methods to compute positional information in an Ising model by transfer
matrices and Monte Carlo sampling are outlined.
article_processing_charge: No
author:
- first_name: Patrick
full_name: Hillenbrand, Patrick
last_name: Hillenbrand
- first_name: Ulrich
full_name: Gerland, Ulrich
last_name: Gerland
- first_name: Gašper
full_name: Tkačik, Gašper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkačik
orcid: 0000-0002-6699-1455
citation:
ama: Hillenbrand P, Gerland U, Tkačik G. Computation of positional information in
an Ising model. 2016. doi:10.1371/journal.pone.0163628.s002
apa: Hillenbrand, P., Gerland, U., & Tkačik, G. (2016). Computation of positional
information in an Ising model. Public Library of Science. https://doi.org/10.1371/journal.pone.0163628.s002
chicago: Hillenbrand, Patrick, Ulrich Gerland, and Gašper Tkačik. “Computation of
Positional Information in an Ising Model.” Public Library of Science, 2016. https://doi.org/10.1371/journal.pone.0163628.s002.
ieee: P. Hillenbrand, U. Gerland, and G. Tkačik, “Computation of positional information
in an Ising model.” Public Library of Science, 2016.
ista: Hillenbrand P, Gerland U, Tkačik G. 2016. Computation of positional information
in an Ising model, Public Library of Science, 10.1371/journal.pone.0163628.s002.
mla: Hillenbrand, Patrick, et al. Computation of Positional Information in an
Ising Model. Public Library of Science, 2016, doi:10.1371/journal.pone.0163628.s002.
short: P. Hillenbrand, U. Gerland, G. Tkačik, (2016).
date_created: 2021-08-10T09:23:45Z
date_published: 2016-09-27T00:00:00Z
date_updated: 2025-09-22T08:46:14Z
day: '27'
department:
- _id: GaTk
doi: 10.1371/journal.pone.0163628.s002
month: '09'
oa_version: Published Version
publisher: Public Library of Science
related_material:
record:
- id: '1270'
relation: used_in_publication
status: public
status: public
title: Computation of positional information in an Ising model
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2016'
...
---
_id: '9871'
abstract:
- lang: eng
text: The positional information in a discrete morphogen field with Gaussian noise
is computed.
article_processing_charge: No
author:
- first_name: Patrick
full_name: Hillenbrand, Patrick
last_name: Hillenbrand
- first_name: Ulrich
full_name: Gerland, Ulrich
last_name: Gerland
- first_name: Gašper
full_name: Tkačik, Gašper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkačik
orcid: 0000-0002-6699-1455
citation:
ama: Hillenbrand P, Gerland U, Tkačik G. Computation of positional information in
a discrete morphogen field. 2016. doi:10.1371/journal.pone.0163628.s003
apa: Hillenbrand, P., Gerland, U., & Tkačik, G. (2016). Computation of positional
information in a discrete morphogen field. Public Library of Science. https://doi.org/10.1371/journal.pone.0163628.s003
chicago: Hillenbrand, Patrick, Ulrich Gerland, and Gašper Tkačik. “Computation of
Positional Information in a Discrete Morphogen Field.” Public Library of Science,
2016. https://doi.org/10.1371/journal.pone.0163628.s003.
ieee: P. Hillenbrand, U. Gerland, and G. Tkačik, “Computation of positional information
in a discrete morphogen field.” Public Library of Science, 2016.
ista: Hillenbrand P, Gerland U, Tkačik G. 2016. Computation of positional information
in a discrete morphogen field, Public Library of Science, 10.1371/journal.pone.0163628.s003.
mla: Hillenbrand, Patrick, et al. Computation of Positional Information in a
Discrete Morphogen Field. Public Library of Science, 2016, doi:10.1371/journal.pone.0163628.s003.
short: P. Hillenbrand, U. Gerland, G. Tkačik, (2016).
date_created: 2021-08-10T09:27:35Z
date_updated: 2025-09-22T08:46:14Z
day: '27'
department:
- _id: GaTk
doi: 10.1371/journal.pone.0163628.s003
month: '09'
oa_version: Published Version
publisher: Public Library of Science
related_material:
record:
- id: '1270'
relation: used_in_publication
status: public
status: public
title: Computation of positional information in a discrete morphogen field
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2016'
...
---
_id: '9873'
article_processing_charge: No
author:
- first_name: Alex
full_name: Boehm, Alex
last_name: Boehm
- first_name: Markus
full_name: Arnoldini, Markus
last_name: Arnoldini
- first_name: Tobias
full_name: Bergmiller, Tobias
id: 2C471CFA-F248-11E8-B48F-1D18A9856A87
last_name: Bergmiller
orcid: 0000-0001-5396-4346
- first_name: Thomas
full_name: Röösli, Thomas
last_name: Röösli
- first_name: Colette
full_name: Bigosch, Colette
last_name: Bigosch
- first_name: Martin
full_name: Ackermann, Martin
last_name: Ackermann
citation:
ama: Boehm A, Arnoldini M, Bergmiller T, Röösli T, Bigosch C, Ackermann M. Quantification
of the growth rate reduction as a consequence of age-specific mortality. 2016.
doi:10.1371/journal.pgen.1005974.s015
apa: Boehm, A., Arnoldini, M., Bergmiller, T., Röösli, T., Bigosch, C., & Ackermann,
M. (2016). Quantification of the growth rate reduction as a consequence of age-specific
mortality. Public Library of Science. https://doi.org/10.1371/journal.pgen.1005974.s015
chicago: Boehm, Alex, Markus Arnoldini, Tobias Bergmiller, Thomas Röösli, Colette
Bigosch, and Martin Ackermann. “Quantification of the Growth Rate Reduction as
a Consequence of Age-Specific Mortality.” Public Library of Science, 2016. https://doi.org/10.1371/journal.pgen.1005974.s015.
ieee: A. Boehm, M. Arnoldini, T. Bergmiller, T. Röösli, C. Bigosch, and M. Ackermann,
“Quantification of the growth rate reduction as a consequence of age-specific
mortality.” Public Library of Science, 2016.
ista: Boehm A, Arnoldini M, Bergmiller T, Röösli T, Bigosch C, Ackermann M. 2016.
Quantification of the growth rate reduction as a consequence of age-specific mortality,
Public Library of Science, 10.1371/journal.pgen.1005974.s015.
mla: Boehm, Alex, et al. Quantification of the Growth Rate Reduction as a Consequence
of Age-Specific Mortality. Public Library of Science, 2016, doi:10.1371/journal.pgen.1005974.s015.
short: A. Boehm, M. Arnoldini, T. Bergmiller, T. Röösli, C. Bigosch, M. Ackermann,
(2016).
date_created: 2021-08-10T09:42:34Z
date_updated: 2025-09-22T09:10:03Z
day: '19'
department:
- _id: CaGu
doi: 10.1371/journal.pgen.1005974.s015
month: '04'
oa_version: Published Version
publisher: Public Library of Science
related_material:
record:
- id: '1250'
relation: used_in_publication
status: public
status: public
title: Quantification of the growth rate reduction as a consequence of age-specific
mortality
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2016'
...
---
OA_type: closed access
_id: '19990'
abstract:
- lang: eng
text: Visualizing molecular localization at high resolution contributes to understanding
of their functions and roles in physiological and pathological conditions. Sodium
dodecyl sulfate-digested freeze-fracture replica labeling (SDS-FRL) is a powerful
electron microscopy method to study high-resolution two-dimensional distribution
of transmembrane proteins and their tightly associated proteins on platinum-carbon
replica. During treatment with SDS, unfixed proteins and intracellular organelle
are dissolved and integral membrane proteins captured and stabilized by carbon
and platinum deposition are denatured, retaining most of their antigenicity, and
exposed on exoplasmic and protoplasmic surfaces of lipid monolayers. The exposure
of these antigens on the surface of replica facilitates the accessibility of antibodies
and therefore provides higher labeling efficiency than those obtained with other
immunoelectron microscopy techniques. In this chapter, we describe the protocols
of SDS-FRL adapted for mammalian brain samples and an additional procedure for
fluorescence-guided electron microscopy for replica immunolabeling.
acknowledgement: We thank Mitsuru Ikeda for preparing replica images used in Fig.
2.
article_processing_charge: No
author:
- first_name: Harumi
full_name: Harada, Harumi
id: 2E55CDF2-F248-11E8-B48F-1D18A9856A87
last_name: Harada
orcid: 0000-0001-7429-7896
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
citation:
ama: 'Harada H, Shigemoto R. High-Resolution Localization of Membrane Proteins by
SDS-Digested Freeze-Fracture Replica Labeling (SDS-FRL). In: Receptor and Ion
Channel Detection in the Brain. Neuromethods. Springer Nature; 2016:233-245.
doi:10.1007/978-1-4939-3064-7_17'
apa: Harada, H., & Shigemoto, R. (2016). High-Resolution Localization of Membrane
Proteins by SDS-Digested Freeze-Fracture Replica Labeling (SDS-FRL). In Receptor
and Ion Channel Detection in the Brain (pp. 233–245). Springer Nature. https://doi.org/10.1007/978-1-4939-3064-7_17
chicago: Harada, Harumi, and Ryuichi Shigemoto. “High-Resolution Localization of
Membrane Proteins by SDS-Digested Freeze-Fracture Replica Labeling (SDS-FRL).”
In Receptor and Ion Channel Detection in the Brain, 233–45. Neuromethods.
Springer Nature, 2016. https://doi.org/10.1007/978-1-4939-3064-7_17.
ieee: H. Harada and R. Shigemoto, “High-Resolution Localization of Membrane Proteins
by SDS-Digested Freeze-Fracture Replica Labeling (SDS-FRL),” in Receptor and
Ion Channel Detection in the Brain, Springer Nature, 2016, pp. 233–245.
ista: 'Harada H, Shigemoto R. 2016.High-Resolution Localization of Membrane Proteins
by SDS-Digested Freeze-Fracture Replica Labeling (SDS-FRL). In: Receptor and Ion
Channel Detection in the Brain. , 233–245.'
mla: Harada, Harumi, and Ryuichi Shigemoto. “High-Resolution Localization of Membrane
Proteins by SDS-Digested Freeze-Fracture Replica Labeling (SDS-FRL).” Receptor
and Ion Channel Detection in the Brain, Springer Nature, 2016, pp. 233–45,
doi:10.1007/978-1-4939-3064-7_17.
short: H. Harada, R. Shigemoto, in:, Receptor and Ion Channel Detection in the Brain,
Springer Nature, 2016, pp. 233–245.
corr_author: '1'
date_created: 2025-07-10T13:56:06Z
date_published: 2016-02-02T00:00:00Z
date_updated: 2026-04-07T08:32:03Z
day: '02'
department:
- _id: RySh
doi: 10.1007/978-1-4939-3064-7_17
language:
- iso: eng
month: '02'
oa_version: None
page: 233-245
publication: Receptor and Ion Channel Detection in the Brain
publication_identifier:
eisbn:
- '9781493930647'
eissn:
- 1940-6045
isbn:
- '9781493930630'
issn:
- 0893-2336
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
series_title: Neuromethods
status: public
title: High-Resolution Localization of Membrane Proteins by SDS-Digested Freeze-Fracture
Replica Labeling (SDS-FRL)
type: book_chapter
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2016'
...
---
_id: '1328'
abstract:
- lang: eng
text: Hole spins have gained considerable interest in the past few years due to
their potential for fast electrically controlled qubits. Here, we study holes
confined in Ge hut wires, a so-far unexplored type of nanostructure. Low-temperature
magnetotransport measurements reveal a large anisotropy between the in-plane and
out-of-plane g-factors of up to 18. Numerical simulations verify that this large
anisotropy originates from a confined wave function of heavy-hole character. A
light-hole admixture of less than 1% is estimated for the states of lowest energy,
leading to a surprisingly large reduction of the out-of-plane g-factors compared
with those for pure heavy holes. Given this tiny light-hole contribution, the
spin lifetimes are expected to be very long, even in isotopically nonpurified
samples.
acknowledgement: 'The work was supported by the EC FP7 ICT project SiSPIN no. 323841,
the EC FP7 ICT project PAMS no. 610446, the ERC Starting Grant no. 335497, the FWF-I-1190-N20
project, and the Swiss NSF. We acknowledge F. Schäffler for fruitful discussions
related to the hut wire growth and for giving us access to the molecular beam epitaxy
system, M. Schatzl for her support in electron beam lithography, and V. Jadris ̌ko
for helping us with the COMSOL simulations. Finally, we thank G. Bauer for his continuous
support. '
article_processing_charge: No
author:
- first_name: Hannes
full_name: Watzinger, Hannes
id: 35DF8E50-F248-11E8-B48F-1D18A9856A87
last_name: Watzinger
- first_name: Christoph
full_name: Kloeffel, Christoph
last_name: Kloeffel
- first_name: Lada
full_name: Vukusic, Lada
id: 31E9F056-F248-11E8-B48F-1D18A9856A87
last_name: Vukusic
orcid: 0000-0003-2424-8636
- first_name: Marta
full_name: Rossell, Marta
last_name: Rossell
- first_name: Violetta
full_name: Sessi, Violetta
last_name: Sessi
- first_name: Josip
full_name: Kukucka, Josip
id: 3F5D8856-F248-11E8-B48F-1D18A9856A87
last_name: Kukucka
- first_name: Raimund
full_name: Kirchschlager, Raimund
last_name: Kirchschlager
- first_name: Elisabeth
full_name: Lausecker, Elisabeth
id: 33662F76-F248-11E8-B48F-1D18A9856A87
last_name: Lausecker
- first_name: Alisha
full_name: Truhlar, Alisha
id: 49CBC780-F248-11E8-B48F-1D18A9856A87
last_name: Truhlar
- first_name: Martin
full_name: Glaser, Martin
last_name: Glaser
- first_name: Armando
full_name: Rastelli, Armando
last_name: Rastelli
- first_name: Andreas
full_name: Fuhrer, Andreas
last_name: Fuhrer
- first_name: Daniel
full_name: Loss, Daniel
last_name: Loss
- first_name: Georgios
full_name: Katsaros, Georgios
id: 38DB5788-F248-11E8-B48F-1D18A9856A87
last_name: Katsaros
orcid: 0000-0001-8342-202X
citation:
ama: Watzinger H, Kloeffel C, Vukušić L, et al. Heavy-hole states in germanium hut
wires. Nano Letters. 2016;16(11):6879-6885. doi:10.1021/acs.nanolett.6b02715
apa: Watzinger, H., Kloeffel, C., Vukušić, L., Rossell, M., Sessi, V., Kukucka,
J., … Katsaros, G. (2016). Heavy-hole states in germanium hut wires. Nano Letters.
American Chemical Society. https://doi.org/10.1021/acs.nanolett.6b02715
chicago: Watzinger, Hannes, Christoph Kloeffel, Lada Vukušić, Marta Rossell, Violetta
Sessi, Josip Kukucka, Raimund Kirchschlager, et al. “Heavy-Hole States in Germanium
Hut Wires.” Nano Letters. American Chemical Society, 2016. https://doi.org/10.1021/acs.nanolett.6b02715.
ieee: H. Watzinger et al., “Heavy-hole states in germanium hut wires,” Nano
Letters, vol. 16, no. 11. American Chemical Society, pp. 6879–6885, 2016.
ista: Watzinger H, Kloeffel C, Vukušić L, Rossell M, Sessi V, Kukucka J, Kirchschlager
R, Lausecker E, Truhlar A, Glaser M, Rastelli A, Fuhrer A, Loss D, Katsaros G.
2016. Heavy-hole states in germanium hut wires. Nano Letters. 16(11), 6879–6885.
mla: Watzinger, Hannes, et al. “Heavy-Hole States in Germanium Hut Wires.” Nano
Letters, vol. 16, no. 11, American Chemical Society, 2016, pp. 6879–85, doi:10.1021/acs.nanolett.6b02715.
short: H. Watzinger, C. Kloeffel, L. Vukušić, M. Rossell, V. Sessi, J. Kukucka,
R. Kirchschlager, E. Lausecker, A. Truhlar, M. Glaser, A. Rastelli, A. Fuhrer,
D. Loss, G. Katsaros, Nano Letters 16 (2016) 6879–6885.
corr_author: '1'
date_created: 2018-12-11T11:51:24Z
date_published: 2016-09-22T00:00:00Z
date_updated: 2026-04-08T07:27:13Z
day: '22'
ddc:
- '539'
department:
- _id: GeKa
doi: 10.1021/acs.nanolett.6b02715
ec_funded: 1
external_id:
isi:
- '000387625000025'
file:
- access_level: open_access
checksum: b63feece90d7b620ece49ca632e34ff3
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:14:04Z
date_updated: 2020-07-14T12:44:44Z
file_id: '5053'
file_name: IST-2016-664-v1+1_acs.nanolett.6b02715.pdf
file_size: 535121
relation: main_file
file_date_updated: 2020-07-14T12:44:44Z
has_accepted_license: '1'
intvolume: ' 16'
isi: 1
issue: '11'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: 6879 - 6885
project:
- _id: 25517E86-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '335497'
name: Towards Spin qubits and Majorana fermions in Germanium self assembled hut-wires
publication: Nano Letters
publication_status: published
publisher: American Chemical Society
publist_id: '5941'
pubrep_id: '664'
quality_controlled: '1'
related_material:
record:
- id: '7977'
relation: popular_science
- id: '7996'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Heavy-hole states in germanium hut wires
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 16
year: '2016'
...
---
_id: '1346'
abstract:
- lang: eng
text: ATP production requires the establishment of an electrochemical proton gradient
across the inner mitochondrial membrane. Mitochondrial uncouplers dissipate this
proton gradient and disrupt numerous cellular processes, including vesicular trafficking,
mainly through energy depletion. Here we show that Endosidin9 (ES9), a novel mitochondrial
uncoupler, is a potent inhibitor of clathrin-mediated endocytosis (CME) in different
systems and that ES9 induces inhibition of CME not because of its effect on cellular
ATP, but rather due to its protonophore activity that leads to cytoplasm acidification.
We show that the known tyrosine kinase inhibitor tyrphostinA23, which is routinely
used to block CME, displays similar properties, thus questioning its use as a
specific inhibitor of cargo recognition by the AP-2 adaptor complex via tyrosine
motif-based endocytosis signals. Furthermore, we show that cytoplasm acidification
dramatically affects the dynamics and recruitment of clathrin and associated adaptors,
and leads to reduction of phosphatidylinositol 4,5-biphosphate from the plasma
membrane.
acknowledgement: "We thank Yvon Jaillais, Ikuko Hara-Nishimura, Akihiko Nakano, Takashi
Ueda and Jinxing Lin for providing materials, Natasha Raikhel, Glenn Hicks, Steffen
Vanneste, and Ricardo Tejos for useful suggestions, Patrick Callaerts for providing
S2 Drosophila cell cultures, Michael Sixt for providing HeLa cells, Annick Bleys
for literature searches, VIB Bio Imaging Core for help with imaging conditions and
Martine De Cock for help in preparing the article. This work was supported by the
Agency for Innovation by Science\r\nand Technology for a pre-doctoral fellowship
to W.D.; the Research fund KU Leuven\r\n(GOA), a Methusalem grant of the Flemish
government and VIB to S.K., J.K. and P.V.;\r\nby the Netherlands Organisation for
Scientific Research (NWO) for ALW grants\r\n846.11.002 (C.T.) and 867.15.020 (T.M.);
the European Research Council (project\r\nERC-2011-StG-20101109 PSDP) (to J.F.);
a European Research Council (ERC) Starting\r\nGrant (grant 260678) (to P.V.), the
Research Foundation-Flanders (grants G.0747.09,\r\nG094011 and G095511) (to P.V.),
the Hercules Foundation, an Interuniversity Attraction\r\nPoles Poles Program, initiated
by the Belgian State, Science Policy Office (to P.V.),\r\nthe Swedish VetenskapsRådet
grant to O.K., the Ghent University ‘Bijzonder\r\nOnderzoek Fonds’ (BOF) for a predoctoral
fellowship to F.A.O.-M., the Research\r\nFoundation-Flanders (FWO) to K.M. and E.R."
article_number: '11710'
article_processing_charge: No
author:
- first_name: Wim
full_name: Dejonghe, Wim
last_name: Dejonghe
- first_name: Sabine
full_name: Kuenen, Sabine
last_name: Kuenen
- first_name: Evelien
full_name: Mylle, Evelien
last_name: Mylle
- first_name: Mina K
full_name: Vasileva, Mina K
id: 3407EB18-F248-11E8-B48F-1D18A9856A87
last_name: Vasileva
- first_name: Olivier
full_name: Keech, Olivier
last_name: Keech
- first_name: Corrado
full_name: Viotti, Corrado
last_name: Viotti
- first_name: Jef
full_name: Swerts, Jef
last_name: Swerts
- first_name: Matyas
full_name: Fendrych, Matyas
id: 43905548-F248-11E8-B48F-1D18A9856A87
last_name: Fendrych
orcid: 0000-0002-9767-8699
- first_name: Fausto
full_name: Ortiz Morea, Fausto
last_name: Ortiz Morea
- first_name: Kiril
full_name: Mishev, Kiril
last_name: Mishev
- first_name: Simon
full_name: Delang, Simon
last_name: Delang
- first_name: Stefan
full_name: Scholl, Stefan
last_name: Scholl
- first_name: Xavier
full_name: Zarza, Xavier
last_name: Zarza
- first_name: Mareike
full_name: Heilmann, Mareike
last_name: Heilmann
- first_name: Jiorgos
full_name: Kourelis, Jiorgos
last_name: Kourelis
- first_name: Jaroslaw
full_name: Kasprowicz, Jaroslaw
last_name: Kasprowicz
- first_name: Le
full_name: Nguyen, Le
last_name: Nguyen
- first_name: Andrzej
full_name: Drozdzecki, Andrzej
last_name: Drozdzecki
- first_name: Isabelle
full_name: Van Houtte, Isabelle
last_name: Van Houtte
- first_name: Anna
full_name: Szatmári, Anna
last_name: Szatmári
- first_name: Mateusz
full_name: Majda, Mateusz
last_name: Majda
- first_name: Gary
full_name: Baisa, Gary
last_name: Baisa
- first_name: Sebastian
full_name: Bednarek, Sebastian
last_name: Bednarek
- first_name: Stéphanie
full_name: Robert, Stéphanie
last_name: Robert
- first_name: Dominique
full_name: Audenaert, Dominique
last_name: Audenaert
- first_name: Christa
full_name: Testerink, Christa
last_name: Testerink
- first_name: Teun
full_name: Munnik, Teun
last_name: Munnik
- first_name: Daniël
full_name: Van Damme, Daniël
last_name: Van Damme
- first_name: Ingo
full_name: Heilmann, Ingo
last_name: Heilmann
- first_name: Karin
full_name: Schumacher, Karin
last_name: Schumacher
- first_name: Johan
full_name: Winne, Johan
last_name: Winne
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Patrik
full_name: Verstreken, Patrik
last_name: Verstreken
- first_name: Eugenia
full_name: Russinova, Eugenia
last_name: Russinova
citation:
ama: Dejonghe W, Kuenen S, Mylle E, et al. Mitochondrial uncouplers inhibit clathrin-mediated
endocytosis largely through cytoplasmic acidification. Nature Communications.
2016;7. doi:10.1038/ncomms11710
apa: Dejonghe, W., Kuenen, S., Mylle, E., Vasileva, M. K., Keech, O., Viotti, C.,
… Russinova, E. (2016). Mitochondrial uncouplers inhibit clathrin-mediated endocytosis
largely through cytoplasmic acidification. Nature Communications. Nature
Publishing Group. https://doi.org/10.1038/ncomms11710
chicago: Dejonghe, Wim, Sabine Kuenen, Evelien Mylle, Mina K Vasileva, Olivier Keech,
Corrado Viotti, Jef Swerts, et al. “Mitochondrial Uncouplers Inhibit Clathrin-Mediated
Endocytosis Largely through Cytoplasmic Acidification.” Nature Communications.
Nature Publishing Group, 2016. https://doi.org/10.1038/ncomms11710.
ieee: W. Dejonghe et al., “Mitochondrial uncouplers inhibit clathrin-mediated
endocytosis largely through cytoplasmic acidification,” Nature Communications,
vol. 7. Nature Publishing Group, 2016.
ista: Dejonghe W, Kuenen S, Mylle E, Vasileva MK, Keech O, Viotti C, Swerts J, Fendrych
M, Ortiz Morea F, Mishev K, Delang S, Scholl S, Zarza X, Heilmann M, Kourelis
J, Kasprowicz J, Nguyen L, Drozdzecki A, Van Houtte I, Szatmári A, Majda M, Baisa
G, Bednarek S, Robert S, Audenaert D, Testerink C, Munnik T, Van Damme D, Heilmann
I, Schumacher K, Winne J, Friml J, Verstreken P, Russinova E. 2016. Mitochondrial
uncouplers inhibit clathrin-mediated endocytosis largely through cytoplasmic acidification.
Nature Communications. 7, 11710.
mla: Dejonghe, Wim, et al. “Mitochondrial Uncouplers Inhibit Clathrin-Mediated Endocytosis
Largely through Cytoplasmic Acidification.” Nature Communications, vol.
7, 11710, Nature Publishing Group, 2016, doi:10.1038/ncomms11710.
short: W. Dejonghe, S. Kuenen, E. Mylle, M.K. Vasileva, O. Keech, C. Viotti, J.
Swerts, M. Fendrych, F. Ortiz Morea, K. Mishev, S. Delang, S. Scholl, X. Zarza,
M. Heilmann, J. Kourelis, J. Kasprowicz, L. Nguyen, A. Drozdzecki, I. Van Houtte,
A. Szatmári, M. Majda, G. Baisa, S. Bednarek, S. Robert, D. Audenaert, C. Testerink,
T. Munnik, D. Van Damme, I. Heilmann, K. Schumacher, J. Winne, J. Friml, P. Verstreken,
E. Russinova, Nature Communications 7 (2016).
date_created: 2018-12-11T11:51:30Z
date_published: 2016-06-08T00:00:00Z
date_updated: 2026-04-08T13:54:44Z
day: '08'
ddc:
- '570'
department:
- _id: JiFr
doi: 10.1038/ncomms11710
ec_funded: 1
external_id:
isi:
- '000377899800001'
file:
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checksum: e8dc81b3e44db5a7718d7f1501ce1aa7
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creator: system
date_created: 2018-12-12T10:18:47Z
date_updated: 2020-07-14T12:44:45Z
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intvolume: ' 7'
isi: 1
language:
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month: '06'
oa: 1
oa_version: Published Version
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '282300'
name: Polarity and subcellular dynamics in plants
publication: Nature Communications
publication_status: published
publisher: Nature Publishing Group
publist_id: '5906'
pubrep_id: '653'
quality_controlled: '1'
related_material:
record:
- id: '7172'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Mitochondrial uncouplers inhibit clathrin-mediated endocytosis largely through
cytoplasmic acidification
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 7
year: '2016'
...
---
_id: '1358'
abstract:
- lang: eng
text: 'Gene regulation relies on the specificity of transcription factor (TF)–DNA
interactions. Limited specificity may lead to crosstalk: a regulatory state in
which a gene is either incorrectly activated due to noncognate TF–DNA interactions
or remains erroneously inactive. As each TF can have numerous interactions with
noncognate cis-regulatory elements, crosstalk is inherently a global problem,
yet has previously not been studied as such. We construct a theoretical framework
to analyse the effects of global crosstalk on gene regulation. We find that crosstalk
presents a significant challenge for organisms with low-specificity TFs, such
as metazoans. Crosstalk is not easily mitigated by known regulatory schemes acting
at equilibrium, including variants of cooperativity and combinatorial regulation.
Our results suggest that crosstalk imposes a previously unexplored global constraint
on the functioning and evolution of regulatory networks, which is qualitatively
distinct from the known constraints that act at the level of individual gene regulatory
elements.'
article_number: '12307'
article_processing_charge: No
author:
- first_name: Tamar
full_name: Friedlander, Tamar
id: 36A5845C-F248-11E8-B48F-1D18A9856A87
last_name: Friedlander
- first_name: Roshan
full_name: Prizak, Roshan
id: 4456104E-F248-11E8-B48F-1D18A9856A87
last_name: Prizak
- first_name: Calin C
full_name: Guet, Calin C
id: 47F8433E-F248-11E8-B48F-1D18A9856A87
last_name: Guet
orcid: 0000-0001-6220-2052
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Gasper
full_name: Tkacik, Gasper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkacik
orcid: 0000-0002-6699-1455
citation:
ama: Friedlander T, Prizak R, Guet CC, Barton NH, Tkačik G. Intrinsic limits to
gene regulation by global crosstalk. Nature Communications. 2016;7. doi:10.1038/ncomms12307
apa: Friedlander, T., Prizak, R., Guet, C. C., Barton, N. H., & Tkačik, G. (2016).
Intrinsic limits to gene regulation by global crosstalk. Nature Communications.
Nature Publishing Group. https://doi.org/10.1038/ncomms12307
chicago: Friedlander, Tamar, Roshan Prizak, Calin C Guet, Nicholas H Barton, and
Gašper Tkačik. “Intrinsic Limits to Gene Regulation by Global Crosstalk.” Nature
Communications. Nature Publishing Group, 2016. https://doi.org/10.1038/ncomms12307.
ieee: T. Friedlander, R. Prizak, C. C. Guet, N. H. Barton, and G. Tkačik, “Intrinsic
limits to gene regulation by global crosstalk,” Nature Communications,
vol. 7. Nature Publishing Group, 2016.
ista: Friedlander T, Prizak R, Guet CC, Barton NH, Tkačik G. 2016. Intrinsic limits
to gene regulation by global crosstalk. Nature Communications. 7, 12307.
mla: Friedlander, Tamar, et al. “Intrinsic Limits to Gene Regulation by Global Crosstalk.”
Nature Communications, vol. 7, 12307, Nature Publishing Group, 2016, doi:10.1038/ncomms12307.
short: T. Friedlander, R. Prizak, C.C. Guet, N.H. Barton, G. Tkačik, Nature Communications
7 (2016).
corr_author: '1'
date_created: 2018-12-11T11:51:34Z
date_published: 2016-08-04T00:00:00Z
date_updated: 2026-04-08T13:54:24Z
day: '04'
ddc:
- '576'
department:
- _id: GaTk
- _id: NiBa
- _id: CaGu
doi: 10.1038/ncomms12307
ec_funded: 1
external_id:
isi:
- '000380858400001'
file:
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checksum: fe3f3a1526d180b29fe691ab11435b78
content_type: application/pdf
creator: system
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date_updated: 2020-07-14T12:44:46Z
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checksum: 164864a1a675f3ad80e9917c27aba07f
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:12:02Z
date_updated: 2020-07-14T12:44:46Z
file_id: '4920'
file_name: IST-2016-627-v1+2_ncomms12307-s1.pdf
file_size: 1084703
relation: main_file
file_date_updated: 2020-07-14T12:44:46Z
has_accepted_license: '1'
intvolume: ' 7'
isi: 1
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
- _id: 25B07788-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '250152'
name: Limits to selection in biology and in evolutionary computation
- _id: 254E9036-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P28844-B27
name: Biophysics of information processing in gene regulation
publication: Nature Communications
publication_status: published
publisher: Nature Publishing Group
publist_id: '5887'
pubrep_id: '627'
quality_controlled: '1'
related_material:
record:
- id: '6071'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Intrinsic limits to gene regulation by global crosstalk
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 7
year: '2016'
...
---
_id: '1096'
article_processing_charge: No
author:
- first_name: Cornelia
full_name: Schwayer, Cornelia
id: 3436488C-F248-11E8-B48F-1D18A9856A87
last_name: Schwayer
orcid: 0000-0001-5130-2226
- first_name: Mateusz K
full_name: Sikora, Mateusz K
id: 2F74BCDE-F248-11E8-B48F-1D18A9856A87
last_name: Sikora
- first_name: Jana
full_name: Slovakova, Jana
id: 30F3F2F0-F248-11E8-B48F-1D18A9856A87
last_name: Slovakova
- first_name: Roland
full_name: Kardos, Roland
id: 4039350E-F248-11E8-B48F-1D18A9856A87
last_name: Kardos
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Schwayer C, Sikora MK, Slovakova J, Kardos R, Heisenberg C-PJ. Actin rings
of power. Developmental Cell. 2016;37(6):493-506. doi:10.1016/j.devcel.2016.05.024
apa: Schwayer, C., Sikora, M. K., Slovakova, J., Kardos, R., & Heisenberg, C.-P.
J. (2016). Actin rings of power. Developmental Cell. Cell Press. https://doi.org/10.1016/j.devcel.2016.05.024
chicago: Schwayer, Cornelia, Mateusz K Sikora, Jana Slovakova, Roland Kardos, and
Carl-Philipp J Heisenberg. “Actin Rings of Power.” Developmental Cell.
Cell Press, 2016. https://doi.org/10.1016/j.devcel.2016.05.024.
ieee: C. Schwayer, M. K. Sikora, J. Slovakova, R. Kardos, and C.-P. J. Heisenberg,
“Actin rings of power,” Developmental Cell, vol. 37, no. 6. Cell Press,
pp. 493–506, 2016.
ista: Schwayer C, Sikora MK, Slovakova J, Kardos R, Heisenberg C-PJ. 2016. Actin
rings of power. Developmental Cell. 37(6), 493–506.
mla: Schwayer, Cornelia, et al. “Actin Rings of Power.” Developmental Cell,
vol. 37, no. 6, Cell Press, 2016, pp. 493–506, doi:10.1016/j.devcel.2016.05.024.
short: C. Schwayer, M.K. Sikora, J. Slovakova, R. Kardos, C.-P.J. Heisenberg, Developmental
Cell 37 (2016) 493–506.
date_created: 2018-12-11T11:50:07Z
date_published: 2016-06-20T00:00:00Z
date_updated: 2026-04-08T13:55:28Z
day: '20'
department:
- _id: CaHe
doi: 10.1016/j.devcel.2016.05.024
external_id:
isi:
- '000378204200005'
intvolume: ' 37'
isi: 1
issue: '6'
language:
- iso: eng
month: '06'
oa_version: None
page: 493 - 506
publication: Developmental Cell
publication_status: published
publisher: Cell Press
publist_id: '6279'
quality_controlled: '1'
related_material:
record:
- id: '7186'
relation: part_of_dissertation
status: public
scopus_import: '1'
status: public
title: Actin rings of power
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 37
year: '2016'
...
---
_id: '1229'
abstract:
- lang: eng
text: Witness encryption (WE) was introduced by Garg et al. [GGSW13]. A WE scheme
is defined for some NP language L and lets a sender encrypt messages relative
to instances x. A ciphertext for x can be decrypted using w witnessing x ∈ L,
but hides the message if x ∈ L. Garg et al. construct WE from multilinear maps
and give another construction [GGH+13b] using indistinguishability obfuscation
(iO) for circuits. Due to the reliance on such heavy tools, WE can cur- rently
hardly be implemented on powerful hardware and will unlikely be realizable on
constrained devices like smart cards any time soon. We construct a WE scheme where
encryption is done by simply computing a Naor-Yung ciphertext (two CPA encryptions
and a NIZK proof). To achieve this, our scheme has a setup phase, which outputs
public parameters containing an obfuscated circuit (only required for decryption),
two encryption keys and a common reference string (used for encryption). This
setup need only be run once, and the parame- ters can be used for arbitrary many
encryptions. Our scheme can also be turned into a functional WE scheme, where
a message is encrypted w.r.t. a statement and a function f, and decryption with
a witness w yields f (m, w). Our construction is inspired by the functional encryption
scheme by Garg et al. and we prove (selective) security assuming iO and statistically
simulation-sound NIZK. We give a construction of the latter in bilinear groups
and combining it with ElGamal encryption, our ciphertexts are of size 1.3 kB at
a 128-bit security level and can be computed on a smart card.
acknowledgement: Research supported by the European Research Council, ERC starting grant
(259668-PSPC) and ERC consolidator grant (682815 - TOCNeT).
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Hamza M
full_name: Abusalah, Hamza M
id: 40297222-F248-11E8-B48F-1D18A9856A87
last_name: Abusalah
- first_name: Georg
full_name: Fuchsbauer, Georg
id: 46B4C3EE-F248-11E8-B48F-1D18A9856A87
last_name: Fuchsbauer
- first_name: Krzysztof Z
full_name: Pietrzak, Krzysztof Z
id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
last_name: Pietrzak
orcid: 0000-0002-9139-1654
citation:
ama: 'Abusalah HM, Fuchsbauer G, Pietrzak KZ. Offline witness encryption. In: Vol
9696. Springer; 2016:285-303. doi:10.1007/978-3-319-39555-5_16'
apa: 'Abusalah, H. M., Fuchsbauer, G., & Pietrzak, K. Z. (2016). Offline witness
encryption (Vol. 9696, pp. 285–303). Presented at the ACNS: Applied Cryptography
and Network Security, Guildford, UK: Springer. https://doi.org/10.1007/978-3-319-39555-5_16'
chicago: Abusalah, Hamza M, Georg Fuchsbauer, and Krzysztof Z Pietrzak. “Offline
Witness Encryption,” 9696:285–303. Springer, 2016. https://doi.org/10.1007/978-3-319-39555-5_16.
ieee: 'H. M. Abusalah, G. Fuchsbauer, and K. Z. Pietrzak, “Offline witness encryption,”
presented at the ACNS: Applied Cryptography and Network Security, Guildford, UK,
2016, vol. 9696, pp. 285–303.'
ista: 'Abusalah HM, Fuchsbauer G, Pietrzak KZ. 2016. Offline witness encryption.
ACNS: Applied Cryptography and Network Security, LNCS, vol. 9696, 285–303.'
mla: Abusalah, Hamza M., et al. Offline Witness Encryption. Vol. 9696, Springer,
2016, pp. 285–303, doi:10.1007/978-3-319-39555-5_16.
short: H.M. Abusalah, G. Fuchsbauer, K.Z. Pietrzak, in:, Springer, 2016, pp. 285–303.
conference:
end_date: 2016-06-22
location: Guildford, UK
name: 'ACNS: Applied Cryptography and Network Security'
start_date: 2016-06-19
date_created: 2018-12-11T11:50:50Z
date_published: 2016-06-09T00:00:00Z
date_updated: 2026-04-08T14:10:21Z
day: '09'
ddc:
- '005'
- '600'
department:
- _id: KrPi
doi: 10.1007/978-3-319-39555-5_16
ec_funded: 1
external_id:
isi:
- '000386324500016'
file:
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checksum: 34fa9ce681da845a1ba945ba3dc57867
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:17:20Z
date_updated: 2020-07-14T12:44:39Z
file_id: '5273'
file_name: IST-2017-765-v1+1_838.pdf
file_size: 515000
relation: main_file
file_date_updated: 2020-07-14T12:44:39Z
has_accepted_license: '1'
intvolume: ' 9696'
isi: 1
language:
- iso: eng
month: '06'
oa: 1
oa_version: Submitted Version
page: 285 - 303
project:
- _id: 258C570E-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '259668'
name: Provable Security for Physical Cryptography
- _id: 258AA5B2-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '682815'
name: Teaching Old Crypto New Tricks
publication_status: published
publisher: Springer
publist_id: '6105'
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quality_controlled: '1'
related_material:
record:
- id: '83'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Offline witness encryption
type: conference
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 9696
year: '2016'
...
---
_id: '1236'
abstract:
- lang: eng
text: 'A constrained pseudorandom function F: K × X → Y for a family T ⊆ 2X of subsets
of X is a function where for any key k ∈ K and set S ∈ T one can efficiently compute
a constrained key kS which allows to evaluate F (k, ·) on all inputs x ∈ S, while
even given this key, the outputs on all inputs x ∉ S look random. At Asiacrypt’13
Boneh and Waters gave a construction which supports the most general set family
so far. Its keys kc are defined for sets decided by boolean circuits C and enable
evaluation of the PRF on any x ∈ X where C(x) = 1. In their construction the PRF
input length and the size of the circuits C for which constrained keys can be
computed must be fixed beforehand during key generation. We construct a constrained
PRF that has an unbounded input length and whose constrained keys can be defined
for any set recognized by a Turing machine. The only a priori bound we make is
on the description size of the machines. We prove our construction secure assuming
publiccoin differing-input obfuscation. As applications of our constrained PRF
we build a broadcast encryption scheme where the number of potential receivers
need not be fixed at setup (in particular, the length of the keys is independent
of the number of parties) and the first identity-based non-interactive key exchange
protocol with no bound on the number of parties that can agree on a shared key.'
acknowledgement: Supported by the European Research Council, ERC Starting Grant (259668-PSPC).
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Hamza M
full_name: Abusalah, Hamza M
id: 40297222-F248-11E8-B48F-1D18A9856A87
last_name: Abusalah
- first_name: Georg
full_name: Fuchsbauer, Georg
id: 46B4C3EE-F248-11E8-B48F-1D18A9856A87
last_name: Fuchsbauer
- first_name: Krzysztof Z
full_name: Pietrzak, Krzysztof Z
id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
last_name: Pietrzak
orcid: 0000-0002-9139-1654
citation:
ama: 'Abusalah HM, Fuchsbauer G, Pietrzak KZ. Constrained PRFs for unbounded inputs.
In: Vol 9610. Springer; 2016:413-428. doi:10.1007/978-3-319-29485-8_24'
apa: 'Abusalah, H. M., Fuchsbauer, G., & Pietrzak, K. Z. (2016). Constrained
PRFs for unbounded inputs (Vol. 9610, pp. 413–428). Presented at the CT-RSA: Topics
in Cryptology, San Francisco, CA, USA: Springer. https://doi.org/10.1007/978-3-319-29485-8_24'
chicago: Abusalah, Hamza M, Georg Fuchsbauer, and Krzysztof Z Pietrzak. “Constrained
PRFs for Unbounded Inputs,” 9610:413–28. Springer, 2016. https://doi.org/10.1007/978-3-319-29485-8_24.
ieee: 'H. M. Abusalah, G. Fuchsbauer, and K. Z. Pietrzak, “Constrained PRFs for
unbounded inputs,” presented at the CT-RSA: Topics in Cryptology, San Francisco,
CA, USA, 2016, vol. 9610, pp. 413–428.'
ista: 'Abusalah HM, Fuchsbauer G, Pietrzak KZ. 2016. Constrained PRFs for unbounded
inputs. CT-RSA: Topics in Cryptology, LNCS, vol. 9610, 413–428.'
mla: Abusalah, Hamza M., et al. Constrained PRFs for Unbounded Inputs. Vol.
9610, Springer, 2016, pp. 413–28, doi:10.1007/978-3-319-29485-8_24.
short: H.M. Abusalah, G. Fuchsbauer, K.Z. Pietrzak, in:, Springer, 2016, pp. 413–428.
conference:
end_date: 2016-03-04
location: San Francisco, CA, USA
name: 'CT-RSA: Topics in Cryptology'
start_date: 2016-02-29
date_created: 2018-12-11T11:50:52Z
date_published: 2016-02-02T00:00:00Z
date_updated: 2026-04-08T14:10:21Z
day: '02'
ddc:
- '005'
- '600'
department:
- _id: KrPi
doi: 10.1007/978-3-319-29485-8_24
ec_funded: 1
external_id:
isi:
- '000374102500024'
file:
- access_level: open_access
checksum: 3851cee49933ae13b1272e516f213e13
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:08:05Z
date_updated: 2020-07-14T12:44:41Z
file_id: '4664'
file_name: IST-2017-764-v1+1_279.pdf
file_size: 495176
relation: main_file
file_date_updated: 2020-07-14T12:44:41Z
has_accepted_license: '1'
intvolume: ' 9610'
isi: 1
language:
- iso: eng
month: '02'
oa: 1
oa_version: Submitted Version
page: 413 - 428
project:
- _id: 258C570E-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '259668'
name: Provable Security for Physical Cryptography
publication_status: published
publisher: Springer
publist_id: '6097'
pubrep_id: '764'
quality_controlled: '1'
related_material:
record:
- id: '83'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Constrained PRFs for unbounded inputs
type: conference
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 9610
year: '2016'
...