---
_id: '2176'
abstract:
- lang: eng
text: Electron microscopy (EM) allows for the simultaneous visualization of all
tissue components at high resolution. However, the extent to which conventional
aldehyde fixation and ethanol dehydration of the tissue alter the fine structure
of cells and organelles, thereby preventing detection of subtle structural changes
induced by an experiment, has remained an issue. Attempts have been made to rapidly
freeze tissue to preserve native ultrastructure. Shock-freezing of living tissue
under high pressure (high-pressure freezing, HPF) followed by cryosubstitution
of the tissue water avoids aldehyde fixation and dehydration in ethanol; the tissue
water is immobilized in â ̂1/450 ms, and a close-to-native fine structure of cells,
organelles and molecules is preserved. Here we describe a protocol for HPF that
is useful to monitor ultrastructural changes associated with functional changes
at synapses in the brain but can be applied to many other tissues as well. The
procedure requires a high-pressure freezer and takes a minimum of 7 d but can
be paused at several points.
article_processing_charge: No
author:
- first_name: Daniel
full_name: Studer, Daniel
last_name: Studer
- first_name: Shanting
full_name: Zhao, Shanting
last_name: Zhao
- first_name: Xuejun
full_name: Chai, Xuejun
last_name: Chai
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
- first_name: Werner
full_name: Graber, Werner
last_name: Graber
- first_name: Sigrun
full_name: Nestel, Sigrun
last_name: Nestel
- first_name: Michael
full_name: Frotscher, Michael
last_name: Frotscher
citation:
ama: Studer D, Zhao S, Chai X, et al. Capture of activity-induced ultrastructural
changes at synapses by high-pressure freezing of brain tissue. Nature Protocols.
2014;9(6):1480-1495. doi:10.1038/nprot.2014.099
apa: Studer, D., Zhao, S., Chai, X., Jonas, P. M., Graber, W., Nestel, S., &
Frotscher, M. (2014). Capture of activity-induced ultrastructural changes at synapses
by high-pressure freezing of brain tissue. Nature Protocols. Nature Publishing
Group. https://doi.org/10.1038/nprot.2014.099
chicago: Studer, Daniel, Shanting Zhao, Xuejun Chai, Peter M Jonas, Werner Graber,
Sigrun Nestel, and Michael Frotscher. “Capture of Activity-Induced Ultrastructural
Changes at Synapses by High-Pressure Freezing of Brain Tissue.” Nature Protocols.
Nature Publishing Group, 2014. https://doi.org/10.1038/nprot.2014.099.
ieee: D. Studer et al., “Capture of activity-induced ultrastructural changes
at synapses by high-pressure freezing of brain tissue,” Nature Protocols,
vol. 9, no. 6. Nature Publishing Group, pp. 1480–1495, 2014.
ista: Studer D, Zhao S, Chai X, Jonas PM, Graber W, Nestel S, Frotscher M. 2014.
Capture of activity-induced ultrastructural changes at synapses by high-pressure
freezing of brain tissue. Nature Protocols. 9(6), 1480–1495.
mla: Studer, Daniel, et al. “Capture of Activity-Induced Ultrastructural Changes
at Synapses by High-Pressure Freezing of Brain Tissue.” Nature Protocols,
vol. 9, no. 6, Nature Publishing Group, 2014, pp. 1480–95, doi:10.1038/nprot.2014.099.
short: D. Studer, S. Zhao, X. Chai, P.M. Jonas, W. Graber, S. Nestel, M. Frotscher,
Nature Protocols 9 (2014) 1480–1495.
date_created: 2018-12-11T11:56:09Z
date_published: 2014-05-29T00:00:00Z
date_updated: 2025-09-29T11:36:43Z
day: '29'
department:
- _id: PeJo
doi: 10.1038/nprot.2014.099
external_id:
isi:
- '000337145800020'
intvolume: ' 9'
isi: 1
issue: '6'
language:
- iso: eng
month: '05'
oa_version: None
page: 1480 - 1495
project:
- _id: 25BDE9A4-B435-11E9-9278-68D0E5697425
grant_number: SFB-TR3-TP10B
name: "Glutamaterge synaptische Ã\x9Cbertragung und Plastizität in hippocampalen
Mikroschaltkreisen"
publication: Nature Protocols
publication_status: published
publisher: Nature Publishing Group
publist_id: '4807'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Capture of activity-induced ultrastructural changes at synapses by high-pressure
freezing of brain tissue
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 9
year: '2014'
...
---
_id: '2177'
abstract:
- lang: eng
text: We give evidence for the difficulty of computing Betti numbers of simplicial
complexes over a finite field. We do this by reducing the rank computation for
sparse matrices with to non-zero entries to computing Betti numbers of simplicial
complexes consisting of at most a constant times to simplices. Together with the
known reduction in the other direction, this implies that the two problems have
the same computational complexity.
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Salman
full_name: Parsa, Salman
id: 4BDBD4F2-F248-11E8-B48F-1D18A9856A87
last_name: Parsa
citation:
ama: 'Edelsbrunner H, Parsa S. On the computational complexity of betti numbers
reductions from matrix rank. In: Proceedings of the Annual ACM-SIAM Symposium
on Discrete Algorithms. SIAM; 2014:152-160. doi:10.1137/1.9781611973402.11'
apa: 'Edelsbrunner, H., & Parsa, S. (2014). On the computational complexity
of betti numbers reductions from matrix rank. In Proceedings of the Annual
ACM-SIAM Symposium on Discrete Algorithms (pp. 152–160). Portland, USA: SIAM.
https://doi.org/10.1137/1.9781611973402.11'
chicago: Edelsbrunner, Herbert, and Salman Parsa. “On the Computational Complexity
of Betti Numbers Reductions from Matrix Rank.” In Proceedings of the Annual
ACM-SIAM Symposium on Discrete Algorithms, 152–60. SIAM, 2014. https://doi.org/10.1137/1.9781611973402.11.
ieee: H. Edelsbrunner and S. Parsa, “On the computational complexity of betti numbers
reductions from matrix rank,” in Proceedings of the Annual ACM-SIAM Symposium
on Discrete Algorithms, Portland, USA, 2014, pp. 152–160.
ista: 'Edelsbrunner H, Parsa S. 2014. On the computational complexity of betti numbers
reductions from matrix rank. Proceedings of the Annual ACM-SIAM Symposium on Discrete
Algorithms. SODA: Symposium on Discrete Algorithms, 152–160.'
mla: Edelsbrunner, Herbert, and Salman Parsa. “On the Computational Complexity of
Betti Numbers Reductions from Matrix Rank.” Proceedings of the Annual ACM-SIAM
Symposium on Discrete Algorithms, SIAM, 2014, pp. 152–60, doi:10.1137/1.9781611973402.11.
short: H. Edelsbrunner, S. Parsa, in:, Proceedings of the Annual ACM-SIAM Symposium
on Discrete Algorithms, SIAM, 2014, pp. 152–160.
conference:
end_date: 2014-01-07
location: Portland, USA
name: 'SODA: Symposium on Discrete Algorithms'
start_date: 2014-01-05
corr_author: '1'
date_created: 2018-12-11T11:56:09Z
date_published: 2014-01-01T00:00:00Z
date_updated: 2024-10-09T20:55:33Z
day: '01'
department:
- _id: HeEd
doi: 10.1137/1.9781611973402.11
language:
- iso: eng
month: '01'
oa_version: None
page: 152 - 160
publication: Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms
publication_status: published
publisher: SIAM
publist_id: '4805'
quality_controlled: '1'
scopus_import: 1
status: public
title: On the computational complexity of betti numbers reductions from matrix rank
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
year: '2014'
...
---
_id: '2178'
abstract:
- lang: eng
text: We consider the three-state toric homogeneous Markov chain model (THMC) without
loops and initial parameters. At time T, the size of the design matrix is 6 ×
3 · 2T-1 and the convex hull of its columns is the model polytope. We study the
behavior of this polytope for T ≥ 3 and we show that it is defined by 24 facets
for all T ≥ 5. Moreover, we give a complete description of these facets. From
this, we deduce that the toric ideal associated with the design matrix is generated
by binomials of degree at most 6. Our proof is based on a result due to Sturmfels,
who gave a bound on the degree of the generators of a toric ideal, provided the
normality of the corresponding toric variety. In our setting, we established the
normality of the toric variety associated to the THMC model by studying the geometric
properties of the model polytope.
acknowledgement: Research of Martín del Campo supported in part by NSF Grant DMS-915211.
article_processing_charge: No
arxiv: 1
author:
- first_name: David
full_name: Haws, David
last_name: Haws
- first_name: Abraham
full_name: Martin Del Campo Sanchez, Abraham
id: 4CF47F6A-F248-11E8-B48F-1D18A9856A87
last_name: Martin Del Campo Sanchez
- first_name: Akimichi
full_name: Takemura, Akimichi
last_name: Takemura
- first_name: Ruriko
full_name: Yoshida, Ruriko
last_name: Yoshida
citation:
ama: Haws D, Martin del Campo Sanchez A, Takemura A, Yoshida R. Markov degree of
the three-state toric homogeneous Markov chain model. Beitrage zur Algebra
und Geometrie. 2014;55(1):161-188. doi:10.1007/s13366-013-0178-y
apa: Haws, D., Martin del Campo Sanchez, A., Takemura, A., & Yoshida, R. (2014).
Markov degree of the three-state toric homogeneous Markov chain model. Beitrage
Zur Algebra Und Geometrie. Springer. https://doi.org/10.1007/s13366-013-0178-y
chicago: Haws, David, Abraham Martin del Campo Sanchez, Akimichi Takemura, and Ruriko
Yoshida. “Markov Degree of the Three-State Toric Homogeneous Markov Chain Model.”
Beitrage Zur Algebra Und Geometrie. Springer, 2014. https://doi.org/10.1007/s13366-013-0178-y.
ieee: D. Haws, A. Martin del Campo Sanchez, A. Takemura, and R. Yoshida, “Markov
degree of the three-state toric homogeneous Markov chain model,” Beitrage zur
Algebra und Geometrie, vol. 55, no. 1. Springer, pp. 161–188, 2014.
ista: Haws D, Martin del Campo Sanchez A, Takemura A, Yoshida R. 2014. Markov degree
of the three-state toric homogeneous Markov chain model. Beitrage zur Algebra
und Geometrie. 55(1), 161–188.
mla: Haws, David, et al. “Markov Degree of the Three-State Toric Homogeneous Markov
Chain Model.” Beitrage Zur Algebra Und Geometrie, vol. 55, no. 1, Springer,
2014, pp. 161–88, doi:10.1007/s13366-013-0178-y.
short: D. Haws, A. Martin del Campo Sanchez, A. Takemura, R. Yoshida, Beitrage Zur
Algebra Und Geometrie 55 (2014) 161–188.
date_created: 2018-12-11T11:56:10Z
date_published: 2014-03-01T00:00:00Z
date_updated: 2025-06-11T07:59:53Z
day: '01'
department:
- _id: CaUh
doi: 10.1007/s13366-013-0178-y
external_id:
arxiv:
- '1204.3070'
intvolume: ' 55'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1204.3070
month: '03'
oa: 1
oa_version: Submitted Version
page: 161 - 188
publication: Beitrage zur Algebra und Geometrie
publication_status: published
publisher: Springer
publist_id: '4804'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Markov degree of the three-state toric homogeneous Markov chain model
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 55
year: '2014'
...
---
_id: '2179'
abstract:
- lang: eng
text: We extend the proof of the local semicircle law for generalized Wigner matrices
given in MR3068390 to the case when the matrix of variances has an eigenvalue
-1. In particular, this result provides a short proof of the optimal local Marchenko-Pastur
law at the hard edge (i.e. around zero) for sample covariance matrices X*X, where
the variances of the entries of X may vary.
article_processing_charge: No
author:
- first_name: Oskari H
full_name: Ajanki, Oskari H
id: 36F2FB7E-F248-11E8-B48F-1D18A9856A87
last_name: Ajanki
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Torben H
full_name: Krüger, Torben H
id: 3020C786-F248-11E8-B48F-1D18A9856A87
last_name: Krüger
orcid: 0000-0002-4821-3297
citation:
ama: Ajanki OH, Erdös L, Krüger TH. Local semicircle law with imprimitive variance
matrix. Electronic Communications in Probability. 2014;19. doi:10.1214/ECP.v19-3121
apa: Ajanki, O. H., Erdös, L., & Krüger, T. H. (2014). Local semicircle law
with imprimitive variance matrix. Electronic Communications in Probability.
Institute of Mathematical Statistics. https://doi.org/10.1214/ECP.v19-3121
chicago: Ajanki, Oskari H, László Erdös, and Torben H Krüger. “Local Semicircle
Law with Imprimitive Variance Matrix.” Electronic Communications in Probability.
Institute of Mathematical Statistics, 2014. https://doi.org/10.1214/ECP.v19-3121.
ieee: O. H. Ajanki, L. Erdös, and T. H. Krüger, “Local semicircle law with imprimitive
variance matrix,” Electronic Communications in Probability, vol. 19. Institute
of Mathematical Statistics, 2014.
ista: Ajanki OH, Erdös L, Krüger TH. 2014. Local semicircle law with imprimitive
variance matrix. Electronic Communications in Probability. 19.
mla: Ajanki, Oskari H., et al. “Local Semicircle Law with Imprimitive Variance Matrix.”
Electronic Communications in Probability, vol. 19, Institute of Mathematical
Statistics, 2014, doi:10.1214/ECP.v19-3121.
short: O.H. Ajanki, L. Erdös, T.H. Krüger, Electronic Communications in Probability
19 (2014).
corr_author: '1'
date_created: 2018-12-11T11:56:10Z
date_published: 2014-06-09T00:00:00Z
date_updated: 2025-09-29T11:35:54Z
day: '09'
ddc:
- '570'
department:
- _id: LaEr
doi: 10.1214/ECP.v19-3121
external_id:
isi:
- '000341869300001'
file:
- access_level: open_access
checksum: bd8a041c76d62fe820bf73ff13ce7d1b
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:09:06Z
date_updated: 2020-07-14T12:45:31Z
file_id: '4729'
file_name: IST-2016-426-v1+1_3121-17518-1-PB.pdf
file_size: 327322
relation: main_file
file_date_updated: 2020-07-14T12:45:31Z
has_accepted_license: '1'
intvolume: ' 19'
isi: 1
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
publication: Electronic Communications in Probability
publication_status: published
publisher: Institute of Mathematical Statistics
publist_id: '4803'
pubrep_id: '426'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Local semicircle law with imprimitive variance matrix
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 19
year: '2014'
...
---
_id: '2180'
abstract:
- lang: eng
text: Weighted majority votes allow one to combine the output of several classifiers
or voters. MinCq is a recent algorithm for optimizing the weight of each voter
based on the minimization of a theoretical bound over the risk of the vote with
elegant PAC-Bayesian generalization guarantees. However, while it has demonstrated
good performance when combining weak classifiers, MinCq cannot make use of the
useful a priori knowledge that one may have when using a mixture of weak and strong
voters. In this paper, we propose P-MinCq, an extension of MinCq that can incorporate
such knowledge in the form of a constraint over the distribution of the weights,
along with general proofs of convergence that stand in the sample compression
setting for data-dependent voters. The approach is applied to a vote of k-NN classifiers
with a specific modeling of the voters' performance. P-MinCq significantly outperforms
the classic k-NN classifier, a symmetric NN and MinCq using the same voters. We
show that it is also competitive with LMNN, a popular metric learning algorithm,
and that combining both approaches further reduces the error.
acknowledgement: 'This work was funded by the French project SoLSTiCe ANR-13-BS02-01
of the ANR. '
article_processing_charge: No
author:
- first_name: Aurélien
full_name: Bellet, Aurélien
last_name: Bellet
- first_name: Amaury
full_name: Habrard, Amaury
last_name: Habrard
- first_name: Emilie
full_name: Morvant, Emilie
id: 4BAC2A72-F248-11E8-B48F-1D18A9856A87
last_name: Morvant
orcid: 0000-0002-8301-7240
- first_name: Marc
full_name: Sebban, Marc
last_name: Sebban
citation:
ama: Bellet A, Habrard A, Morvant E, Sebban M. Learning a priori constrained weighted
majority votes. Machine Learning. 2014;97(1-2):129-154. doi:10.1007/s10994-014-5462-z
apa: Bellet, A., Habrard, A., Morvant, E., & Sebban, M. (2014). Learning a priori
constrained weighted majority votes. Machine Learning. Springer. https://doi.org/10.1007/s10994-014-5462-z
chicago: Bellet, Aurélien, Amaury Habrard, Emilie Morvant, and Marc Sebban. “Learning
a Priori Constrained Weighted Majority Votes.” Machine Learning. Springer,
2014. https://doi.org/10.1007/s10994-014-5462-z.
ieee: A. Bellet, A. Habrard, E. Morvant, and M. Sebban, “Learning a priori constrained
weighted majority votes,” Machine Learning, vol. 97, no. 1–2. Springer,
pp. 129–154, 2014.
ista: Bellet A, Habrard A, Morvant E, Sebban M. 2014. Learning a priori constrained
weighted majority votes. Machine Learning. 97(1–2), 129–154.
mla: Bellet, Aurélien, et al. “Learning a Priori Constrained Weighted Majority Votes.”
Machine Learning, vol. 97, no. 1–2, Springer, 2014, pp. 129–54, doi:10.1007/s10994-014-5462-z.
short: A. Bellet, A. Habrard, E. Morvant, M. Sebban, Machine Learning 97 (2014)
129–154.
corr_author: '1'
date_created: 2018-12-11T11:56:10Z
date_published: 2014-10-01T00:00:00Z
date_updated: 2025-09-29T11:35:24Z
day: '01'
department:
- _id: ChLa
doi: 10.1007/s10994-014-5462-z
ec_funded: 1
external_id:
isi:
- '000341431300007'
intvolume: ' 97'
isi: 1
issue: 1-2
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://hal.archives-ouvertes.fr/hal-01009578/document
month: '10'
oa: 1
oa_version: Submitted Version
page: 129 - 154
project:
- _id: 2532554C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '308036'
name: Lifelong Learning of Visual Scene Understanding
publication: Machine Learning
publication_status: published
publisher: Springer
publist_id: '4802'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Learning a priori constrained weighted majority votes
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 97
year: '2014'
...
---
_id: '2183'
abstract:
- lang: eng
text: 'We describe a simple adaptive network of coupled chaotic maps. The network
reaches a stationary state (frozen topology) for all values of the coupling parameter,
although the dynamics of the maps at the nodes of the network can be nontrivial.
The structure of the network shows interesting hierarchical properties and in
certain parameter regions the dynamics is polysynchronous: Nodes can be divided
in differently synchronized classes but, contrary to cluster synchronization,
nodes in the same class need not be connected to each other. These complicated
synchrony patterns have been conjectured to play roles in systems biology and
circuits. The adaptive system we study describes ways whereby this behavior can
evolve from undifferentiated nodes.'
acknowledgement: "V.B.S. is partially supported by contract MEC (Grant No. AYA2010-22111-C03-02).\r\n"
article_number: '062809'
article_processing_charge: No
arxiv: 1
author:
- first_name: Vicente
full_name: Botella Soler, Vicente
id: 421234E8-F248-11E8-B48F-1D18A9856A87
last_name: Botella Soler
orcid: 0000-0002-8790-1914
- first_name: Paul
full_name: Glendinning, Paul
last_name: Glendinning
citation:
ama: Botella Soler V, Glendinning P. Hierarchy and polysynchrony in an adaptive
network . Physical Review E Statistical Nonlinear and Soft Matter Physics.
2014;89(6). doi:10.1103/PhysRevE.89.062809
apa: Botella Soler, V., & Glendinning, P. (2014). Hierarchy and polysynchrony
in an adaptive network . Physical Review E Statistical Nonlinear and Soft Matter
Physics. American Institute of Physics. https://doi.org/10.1103/PhysRevE.89.062809
chicago: Botella Soler, Vicente, and Paul Glendinning. “Hierarchy and Polysynchrony
in an Adaptive Network .” Physical Review E Statistical Nonlinear and Soft
Matter Physics. American Institute of Physics, 2014. https://doi.org/10.1103/PhysRevE.89.062809.
ieee: V. Botella Soler and P. Glendinning, “Hierarchy and polysynchrony in an adaptive
network ,” Physical Review E Statistical Nonlinear and Soft Matter Physics,
vol. 89, no. 6. American Institute of Physics, 2014.
ista: Botella Soler V, Glendinning P. 2014. Hierarchy and polysynchrony in an adaptive
network . Physical Review E Statistical Nonlinear and Soft Matter Physics. 89(6),
062809.
mla: Botella Soler, Vicente, and Paul Glendinning. “Hierarchy and Polysynchrony
in an Adaptive Network .” Physical Review E Statistical Nonlinear and Soft
Matter Physics, vol. 89, no. 6, 062809, American Institute of Physics, 2014,
doi:10.1103/PhysRevE.89.062809.
short: V. Botella Soler, P. Glendinning, Physical Review E Statistical Nonlinear
and Soft Matter Physics 89 (2014).
corr_author: '1'
date_created: 2018-12-11T11:56:11Z
date_published: 2014-06-16T00:00:00Z
date_updated: 2025-09-29T11:34:45Z
day: '16'
department:
- _id: GaTk
doi: 10.1103/PhysRevE.89.062809
ec_funded: 1
external_id:
arxiv:
- '1403.3209'
isi:
- '000337733900007'
intvolume: ' 89'
isi: 1
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1403.3209
month: '06'
oa: 1
oa_version: Preprint
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Physical Review E Statistical Nonlinear and Soft Matter Physics
publication_status: published
publisher: American Institute of Physics
publist_id: '4798'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Hierarchy and polysynchrony in an adaptive network '
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 89
year: '2014'
...
---
_id: '2184'
abstract:
- lang: eng
text: 'Given topological spaces X,Y, a fundamental problem of algebraic topology
is understanding the structure of all continuous maps X→ Y. We consider a computational
version, where X,Y are given as finite simplicial complexes, and the goal is to
compute [X,Y], that is, all homotopy classes of suchmaps.We solve this problem
in the stable range, where for some d ≥ 2, we have dim X ≤ 2d-2 and Y is (d-1)-connected;
in particular, Y can be the d-dimensional sphere Sd. The algorithm combines classical
tools and ideas from homotopy theory (obstruction theory, Postnikov systems, and
simplicial sets) with algorithmic tools from effective algebraic topology (locally
effective simplicial sets and objects with effective homology). In contrast, [X,Y]
is known to be uncomputable for general X,Y, since for X = S1 it includes a well
known undecidable problem: testing triviality of the fundamental group of Y. In
follow-up papers, the algorithm is shown to run in polynomial time for d fixed,
and extended to other problems, such as the extension problem, where we are given
a subspace A ⊂ X and a map A→ Y and ask whether it extends to a map X → Y, or
computing the Z2-index-everything in the stable range. Outside the stable range,
the extension problem is undecidable.'
acknowledgement: The research by M. K. was supported by project GAUK 49209. The research
by M. K. was also supported by project 1M0545 by the Ministry of Education of the
Czech Republic and by Center of Excellence { Inst. for Theor. Comput. Sci., Prague
(project P202/12/G061 of GACR). The research by U. W. was supported by the Swiss
National Science Foundation (SNF Projects 200021-125309, 200020-138230, and PP00P2-138948).
article_number: '17 '
article_processing_charge: No
arxiv: 1
author:
- first_name: Martin
full_name: Čadek, Martin
last_name: Čadek
- first_name: Marek
full_name: Krcál, Marek
id: 33E21118-F248-11E8-B48F-1D18A9856A87
last_name: Krcál
- first_name: Jiří
full_name: Matoušek, Jiří
last_name: Matoušek
- first_name: Francis
full_name: Sergeraert, Francis
last_name: Sergeraert
- first_name: Lukáš
full_name: Vokřínek, Lukáš
last_name: Vokřínek
- first_name: Uli
full_name: Wagner, Uli
id: 36690CA2-F248-11E8-B48F-1D18A9856A87
last_name: Wagner
orcid: 0000-0002-1494-0568
citation:
ama: Čadek M, Krcál M, Matoušek J, Sergeraert F, Vokřínek L, Wagner U. Computing
all maps into a sphere. Journal of the ACM. 2014;61(3). doi:10.1145/2597629
apa: Čadek, M., Krcál, M., Matoušek, J., Sergeraert, F., Vokřínek, L., & Wagner,
U. (2014). Computing all maps into a sphere. Journal of the ACM. ACM. https://doi.org/10.1145/2597629
chicago: Čadek, Martin, Marek Krcál, Jiří Matoušek, Francis Sergeraert, Lukáš Vokřínek,
and Uli Wagner. “Computing All Maps into a Sphere.” Journal of the ACM.
ACM, 2014. https://doi.org/10.1145/2597629.
ieee: M. Čadek, M. Krcál, J. Matoušek, F. Sergeraert, L. Vokřínek, and U. Wagner,
“Computing all maps into a sphere,” Journal of the ACM, vol. 61, no. 3.
ACM, 2014.
ista: Čadek M, Krcál M, Matoušek J, Sergeraert F, Vokřínek L, Wagner U. 2014. Computing
all maps into a sphere. Journal of the ACM. 61(3), 17.
mla: Čadek, Martin, et al. “Computing All Maps into a Sphere.” Journal of the
ACM, vol. 61, no. 3, 17, ACM, 2014, doi:10.1145/2597629.
short: M. Čadek, M. Krcál, J. Matoušek, F. Sergeraert, L. Vokřínek, U. Wagner, Journal
of the ACM 61 (2014).
date_created: 2018-12-11T11:56:12Z
date_published: 2014-05-01T00:00:00Z
date_updated: 2025-09-29T11:34:15Z
day: '01'
department:
- _id: UlWa
- _id: HeEd
doi: 10.1145/2597629
external_id:
arxiv:
- '1105.6257'
isi:
- '000337201400003'
intvolume: ' 61'
isi: 1
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1105.6257
month: '05'
oa: 1
oa_version: Preprint
publication: Journal of the ACM
publication_status: published
publisher: ACM
publist_id: '4797'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Computing all maps into a sphere
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 61
year: '2014'
...
---
_id: '2185'
abstract:
- lang: eng
text: 'We revisit the classical problem of converting an imperfect source of randomness
into a usable cryptographic key. Assume that we have some cryptographic application
P that expects a uniformly random m-bit key R and ensures that the best attack
(in some complexity class) against P(R) has success probability at most δ. Our
goal is to design a key-derivation function (KDF) h that converts any random source
X of min-entropy k into a sufficiently "good" key h(X), guaranteeing
that P(h(X)) has comparable security δ′ which is ''close'' to δ. Seeded randomness
extractors provide a generic way to solve this problem for all applications P,
with resulting security δ′ = O(δ), provided that we start with entropy k ≥ m +
2 log (1/δ) - O(1). By a result of Radhakrishnan and Ta-Shma, this bound on k
(called the "RT-bound") is also known to be tight in general. Unfortunately,
in many situations the loss of 2 log (1/δ) bits of entropy is unacceptable. This
motivates the study KDFs with less entropy waste by placing some restrictions
on the source X or the application P. In this work we obtain the following new
positive and negative results in this regard: - Efficient samplability of the
source X does not help beat the RT-bound for general applications. This resolves
the SRT (samplable RT) conjecture of Dachman-Soled et al. [DGKM12] in the affirmative,
and also shows that the existence of computationally-secure extractors beating
the RT-bound implies the existence of one-way functions. - We continue in the
line of work initiated by Barak et al. [BDK+11] and construct new information-theoretic
KDFs which beat the RT-bound for large but restricted classes of applications.
Specifically, we design efficient KDFs that work for all unpredictability applications
P (e.g., signatures, MACs, one-way functions, etc.) and can either: (1) extract
all of the entropy k = m with a very modest security loss δ′ = O(δ·log (1/δ)),
or alternatively, (2) achieve essentially optimal security δ′ = O(δ) with a very
modest entropy loss k ≥ m + loglog (1/δ). In comparison, the best prior results
from [BDK+11] for this class of applications would only guarantee δ′ = O(√δ) when
k = m, and would need k ≥ m + log (1/δ) to get δ′ = O(δ). - The weaker bounds
of [BDK+11] hold for a larger class of so-called "square- friendly"
applications (which includes all unpredictability, but also some important indistinguishability,
applications). Unfortunately, we show that these weaker bounds are tight for the
larger class of applications. - We abstract out a clean, information-theoretic
notion of (k,δ,δ′)- unpredictability extractors, which guarantee "induced"
security δ′ for any δ-secure unpredictability application P, and characterize
the parameters achievable for such unpredictability extractors. Of independent
interest, we also relate this notion to the previously-known notion of (min-entropy)
condensers, and improve the state-of-the-art parameters for such condensers.'
alternative_title:
- LNCS
author:
- first_name: Yevgeniy
full_name: Dodis, Yevgeniy
last_name: Dodis
- first_name: Krzysztof Z
full_name: Pietrzak, Krzysztof Z
id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
last_name: Pietrzak
orcid: 0000-0002-9139-1654
- first_name: Daniel
full_name: Wichs, Daniel
last_name: Wichs
citation:
ama: 'Dodis Y, Pietrzak KZ, Wichs D. Key derivation without entropy waste. In: Nguyen
P, Oswald E, eds. Vol 8441. Springer; 2014:93-110. doi:10.1007/978-3-642-55220-5_6'
apa: 'Dodis, Y., Pietrzak, K. Z., & Wichs, D. (2014). Key derivation without
entropy waste. In P. Nguyen & E. Oswald (Eds.) (Vol. 8441, pp. 93–110). Presented
at the EUROCRYPT: Theory and Applications of Cryptographic Techniques, Copenhagen,
Denmark: Springer. https://doi.org/10.1007/978-3-642-55220-5_6'
chicago: Dodis, Yevgeniy, Krzysztof Z Pietrzak, and Daniel Wichs. “Key Derivation
without Entropy Waste.” edited by Phong Nguyen and Elisabeth Oswald, 8441:93–110.
Springer, 2014. https://doi.org/10.1007/978-3-642-55220-5_6.
ieee: 'Y. Dodis, K. Z. Pietrzak, and D. Wichs, “Key derivation without entropy waste,”
presented at the EUROCRYPT: Theory and Applications of Cryptographic Techniques,
Copenhagen, Denmark, 2014, vol. 8441, pp. 93–110.'
ista: 'Dodis Y, Pietrzak KZ, Wichs D. 2014. Key derivation without entropy waste.
EUROCRYPT: Theory and Applications of Cryptographic Techniques, LNCS, vol. 8441,
93–110.'
mla: Dodis, Yevgeniy, et al. Key Derivation without Entropy Waste. Edited
by Phong Nguyen and Elisabeth Oswald, vol. 8441, Springer, 2014, pp. 93–110, doi:10.1007/978-3-642-55220-5_6.
short: Y. Dodis, K.Z. Pietrzak, D. Wichs, in:, P. Nguyen, E. Oswald (Eds.), Springer,
2014, pp. 93–110.
conference:
end_date: 2014-05-15
location: Copenhagen, Denmark
name: 'EUROCRYPT: Theory and Applications of Cryptographic Techniques'
start_date: 2014-05-11
date_created: 2018-12-11T11:56:12Z
date_published: 2014-04-01T00:00:00Z
date_updated: 2021-01-12T06:55:51Z
day: '01'
ddc:
- '000'
- '004'
department:
- _id: KrPi
doi: 10.1007/978-3-642-55220-5_6
editor:
- first_name: Phong
full_name: Nguyen, Phong
last_name: Nguyen
- first_name: Elisabeth
full_name: Oswald, Elisabeth
last_name: Oswald
file:
- access_level: open_access
checksum: da1aa01221086083b23c92e547b48ff4
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:08:43Z
date_updated: 2020-07-14T12:45:31Z
file_id: '4705'
file_name: IST-2016-680-v1+1_708.pdf
file_size: 505389
relation: main_file
file_date_updated: 2020-07-14T12:45:31Z
has_accepted_license: '1'
intvolume: ' 8441'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Submitted Version
page: 93 - 110
publication_status: published
publisher: Springer
publist_id: '4795'
pubrep_id: '680'
quality_controlled: '1'
scopus_import: 1
status: public
title: Key derivation without entropy waste
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 8441
year: '2014'
...
---
_id: '2186'
abstract:
- lang: eng
text: We prove the existence of scattering states for the defocusing cubic Gross-Pitaevskii
(GP) hierarchy in ℝ3. Moreover, we show that an exponential energy growth condition
commonly used in the well-posedness theory of the GP hierarchy is, in a specific
sense, necessary. In fact, we prove that without the latter, there exist initial
data for the focusing cubic GP hierarchy for which instantaneous blowup occurs.
article_processing_charge: No
arxiv: 1
author:
- first_name: Thomas
full_name: Chen, Thomas
last_name: Chen
- first_name: Christian
full_name: Hainzl, Christian
last_name: Hainzl
- first_name: Nataša
full_name: Pavlović, Nataša
last_name: Pavlović
- first_name: Robert
full_name: Seiringer, Robert
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: Chen T, Hainzl C, Pavlović N, Seiringer R. On the well-posedness and scattering
for the Gross-Pitaevskii hierarchy via quantum de Finetti. Letters in Mathematical
Physics. 2014;104(7):871-891. doi:10.1007/s11005-014-0693-2
apa: Chen, T., Hainzl, C., Pavlović, N., & Seiringer, R. (2014). On the well-posedness
and scattering for the Gross-Pitaevskii hierarchy via quantum de Finetti. Letters
in Mathematical Physics. Springer. https://doi.org/10.1007/s11005-014-0693-2
chicago: Chen, Thomas, Christian Hainzl, Nataša Pavlović, and Robert Seiringer.
“On the Well-Posedness and Scattering for the Gross-Pitaevskii Hierarchy via Quantum
de Finetti.” Letters in Mathematical Physics. Springer, 2014. https://doi.org/10.1007/s11005-014-0693-2.
ieee: T. Chen, C. Hainzl, N. Pavlović, and R. Seiringer, “On the well-posedness
and scattering for the Gross-Pitaevskii hierarchy via quantum de Finetti,” Letters
in Mathematical Physics, vol. 104, no. 7. Springer, pp. 871–891, 2014.
ista: Chen T, Hainzl C, Pavlović N, Seiringer R. 2014. On the well-posedness and
scattering for the Gross-Pitaevskii hierarchy via quantum de Finetti. Letters
in Mathematical Physics. 104(7), 871–891.
mla: Chen, Thomas, et al. “On the Well-Posedness and Scattering for the Gross-Pitaevskii
Hierarchy via Quantum de Finetti.” Letters in Mathematical Physics, vol.
104, no. 7, Springer, 2014, pp. 871–91, doi:10.1007/s11005-014-0693-2.
short: T. Chen, C. Hainzl, N. Pavlović, R. Seiringer, Letters in Mathematical Physics
104 (2014) 871–891.
date_created: 2018-12-11T11:56:12Z
date_published: 2014-05-07T00:00:00Z
date_updated: 2025-09-29T11:33:31Z
day: '07'
department:
- _id: RoSe
doi: 10.1007/s11005-014-0693-2
external_id:
arxiv:
- '1311.2136'
isi:
- '000336412300005'
intvolume: ' 104'
isi: 1
issue: '7'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1311.2136
month: '05'
oa: 1
oa_version: Submitted Version
page: 871 - 891
project:
- _id: 26450934-B435-11E9-9278-68D0E5697425
name: NSERC Postdoctoral fellowship
publication: Letters in Mathematical Physics
publication_status: published
publisher: Springer
publist_id: '4793'
quality_controlled: '1'
scopus_import: '1'
status: public
title: On the well-posedness and scattering for the Gross-Pitaevskii hierarchy via
quantum de Finetti
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 104
year: '2014'
...
---
_id: '2187'
abstract:
- lang: eng
text: 'Systems should not only be correct but also robust in the sense that they
behave reasonably in unexpected situations. This article addresses synthesis of
robust reactive systems from temporal specifications. Existing methods allow arbitrary
behavior if assumptions in the specification are violated. To overcome this, we
define two robustness notions, combine them, and show how to enforce them in synthesis.
The first notion applies to safety properties: If safety assumptions are violated
temporarily, we require that the system recovers to normal operation with as few
errors as possible. The second notion requires that, if liveness assumptions are
violated, as many guarantees as possible should be fulfilled nevertheless. We
present a synthesis procedure achieving this for the important class of GR(1)
specifications, and establish complexity bounds. We also present an implementation
of a special case of robustness, and show experimental results.'
article_processing_charge: No
article_type: original
author:
- first_name: Roderick
full_name: Bloem, Roderick
last_name: Bloem
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Karin
full_name: Greimel, Karin
last_name: Greimel
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Georg
full_name: Hofferek, Georg
last_name: Hofferek
- first_name: Barbara
full_name: Jobstmann, Barbara
last_name: Jobstmann
- first_name: Bettina
full_name: Könighofer, Bettina
last_name: Könighofer
- first_name: Robert
full_name: Könighofer, Robert
last_name: Könighofer
citation:
ama: Bloem R, Chatterjee K, Greimel K, et al. Synthesizing robust systems. Acta
Informatica. 2014;51(3-4):193-220. doi:10.1007/s00236-013-0191-5
apa: Bloem, R., Chatterjee, K., Greimel, K., Henzinger, T. A., Hofferek, G., Jobstmann,
B., … Könighofer, R. (2014). Synthesizing robust systems. Acta Informatica.
Springer. https://doi.org/10.1007/s00236-013-0191-5
chicago: Bloem, Roderick, Krishnendu Chatterjee, Karin Greimel, Thomas A Henzinger,
Georg Hofferek, Barbara Jobstmann, Bettina Könighofer, and Robert Könighofer.
“Synthesizing Robust Systems.” Acta Informatica. Springer, 2014. https://doi.org/10.1007/s00236-013-0191-5.
ieee: R. Bloem et al., “Synthesizing robust systems,” Acta Informatica,
vol. 51, no. 3–4. Springer, pp. 193–220, 2014.
ista: Bloem R, Chatterjee K, Greimel K, Henzinger TA, Hofferek G, Jobstmann B, Könighofer
B, Könighofer R. 2014. Synthesizing robust systems. Acta Informatica. 51(3–4),
193–220.
mla: Bloem, Roderick, et al. “Synthesizing Robust Systems.” Acta Informatica,
vol. 51, no. 3–4, Springer, 2014, pp. 193–220, doi:10.1007/s00236-013-0191-5.
short: R. Bloem, K. Chatterjee, K. Greimel, T.A. Henzinger, G. Hofferek, B. Jobstmann,
B. Könighofer, R. Könighofer, Acta Informatica 51 (2014) 193–220.
date_created: 2018-12-11T11:56:13Z
date_published: 2014-06-01T00:00:00Z
date_updated: 2025-09-29T11:32:51Z
day: '01'
ddc:
- '621'
department:
- _id: KrCh
- _id: ToHe
doi: 10.1007/s00236-013-0191-5
ec_funded: 1
external_id:
isi:
- '000335981500004'
file:
- access_level: open_access
checksum: d7f560f3d923f0f00aa10a0652f83273
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:16:44Z
date_updated: 2020-07-14T12:45:31Z
file_id: '5234'
file_name: IST-2012-71-v1+1_Synthesizing_robust_systems.pdf
file_size: 169523
relation: main_file
file_date_updated: 2020-07-14T12:45:31Z
has_accepted_license: '1'
intvolume: ' 51'
isi: 1
issue: 3-4
language:
- iso: eng
month: '06'
oa: 1
oa_version: Submitted Version
page: 193 - 220
project:
- _id: 25F5A88A-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11402-N23
name: Moderne Concurrency Paradigms
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
publication: Acta Informatica
publication_status: published
publisher: Springer
publist_id: '4787'
pubrep_id: '71'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Synthesizing robust systems
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 51
year: '2014'
...
---
_id: '2188'
abstract:
- lang: eng
text: Although plant and animal cells use a similar core mechanism to deliver proteins
to the plasma membrane, their different lifestyle, body organization and specific
cell structures resulted in the acquisition of regulatory mechanisms that vary
in the two kingdoms. In particular, cell polarity regulators do not seem to be
conserved, because genes encoding key components are absent in plant genomes.
In plants, the broad knowledge on polarity derives from the study of auxin transporters,
the PIN-FORMED proteins, in the model plant Arabidopsis thaliana. In animals,
much information is provided from the study of polarity in epithelial cells that
exhibit basolateral and luminal apical polarities, separated by tight junctions.
In this review, we summarize the similarities and differences of the polarization
mechanisms between plants and animals and survey the main genetic approaches that
have been used to characterize new genes involved in polarity establishment in
plants, including the frequently used forward and reverse genetics screens as
well as a novel chemical genetics approach that is expected to overcome the limitation
of classical genetics methods.
acknowledgement: "This work was supported by a grant from the Research Foundation-Flanders
(Odysseus).\r\n\r\n"
article_number: '140017'
article_processing_charge: No
author:
- first_name: Urszula
full_name: Kania, Urszula
id: 4AE5C486-F248-11E8-B48F-1D18A9856A87
last_name: Kania
- first_name: Matyas
full_name: Fendrych, Matyas
last_name: Fendrych
- first_name: Jiřĺ
full_name: Friml, Jiřĺ
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Kania U, Fendrych M, Friml J. Polar delivery in plants; commonalities and differences
to animal epithelial cells. Open Biology. 2014;4(APRIL). doi:10.1098/rsob.140017
apa: Kania, U., Fendrych, M., & Friml, J. (2014). Polar delivery in plants;
commonalities and differences to animal epithelial cells. Open Biology.
Royal Society. https://doi.org/10.1098/rsob.140017
chicago: Kania, Urszula, Matyas Fendrych, and Jiří Friml. “Polar Delivery in Plants;
Commonalities and Differences to Animal Epithelial Cells.” Open Biology.
Royal Society, 2014. https://doi.org/10.1098/rsob.140017.
ieee: U. Kania, M. Fendrych, and J. Friml, “Polar delivery in plants; commonalities
and differences to animal epithelial cells,” Open Biology, vol. 4, no.
APRIL. Royal Society, 2014.
ista: Kania U, Fendrych M, Friml J. 2014. Polar delivery in plants; commonalities
and differences to animal epithelial cells. Open Biology. 4(APRIL), 140017.
mla: Kania, Urszula, et al. “Polar Delivery in Plants; Commonalities and Differences
to Animal Epithelial Cells.” Open Biology, vol. 4, no. APRIL, 140017, Royal
Society, 2014, doi:10.1098/rsob.140017.
short: U. Kania, M. Fendrych, J. Friml, Open Biology 4 (2014).
corr_author: '1'
date_created: 2018-12-11T11:56:13Z
date_published: 2014-04-16T00:00:00Z
date_updated: 2025-09-29T11:32:17Z
day: '16'
ddc:
- '570'
department:
- _id: JiFr
doi: 10.1098/rsob.140017
external_id:
isi:
- '000335813800006'
file:
- access_level: open_access
checksum: 2020627feff36cf0799167c84149fa75
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:13:40Z
date_updated: 2020-07-14T12:45:31Z
file_id: '5025'
file_name: IST-2016-441-v1+1_140017.full.pdf
file_size: 682570
relation: main_file
file_date_updated: 2020-07-14T12:45:31Z
has_accepted_license: '1'
intvolume: ' 4'
isi: 1
issue: APRIL
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
publication: Open Biology
publication_status: published
publisher: Royal Society
publist_id: '4786'
pubrep_id: '441'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Polar delivery in plants; commonalities and differences to animal epithelial
cells
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 4
year: '2014'
...
---
_id: '2189'
abstract:
- lang: fre
text: En apprentissage automatique, nous parlons d'adaptation de domaine lorsque
les données de test (cibles) et d'apprentissage (sources) sont générées selon
différentes distributions. Nous devons donc développer des algorithmes de classification
capables de s'adapter à une nouvelle distribution, pour laquelle aucune information
sur les étiquettes n'est disponible. Nous attaquons cette problématique sous l'angle
de l'approche PAC-Bayésienne qui se focalise sur l'apprentissage de modèles définis
comme des votes de majorité sur un ensemble de fonctions. Dans ce contexte, nous
introduisons PV-MinCq une version adaptative de l'algorithme (non adaptatif) MinCq.
PV-MinCq suit le principe suivant. Nous transférons les étiquettes sources aux
points cibles proches pour ensuite appliquer MinCq sur l'échantillon cible ``auto-étiqueté''
(justifié par une borne théorique). Plus précisément, nous définissons un auto-étiquetage
non itératif qui se focalise dans les régions où les distributions marginales
source et cible sont les plus similaires. Dans un second temps, nous étudions
l'influence de notre auto-étiquetage pour en déduire une procédure de validation
des hyperparamètres. Finalement, notre approche montre des résultats empiriques
prometteurs.
article_processing_charge: No
author:
- first_name: Emilie
full_name: Morvant, Emilie
id: 4BAC2A72-F248-11E8-B48F-1D18A9856A87
last_name: Morvant
orcid: 0000-0002-8301-7240
citation:
ama: 'Morvant E. Adaptation de domaine de vote de majorité par auto-étiquetage non
itératif. In: Vol 1. Elsevier; 2014:49-58.'
apa: 'Morvant, E. (2014). Adaptation de domaine de vote de majorité par auto-étiquetage
non itératif (Vol. 1, pp. 49–58). Presented at the CAP: Conférence Francophone
sur l’Apprentissage Automatique (Machine Learning French Conference), Saint-Etienne,
France: Elsevier.'
chicago: Morvant, Emilie. “Adaptation de Domaine de Vote de Majorité Par Auto-Étiquetage
Non Itératif,” 1:49–58. Elsevier, 2014.
ieee: 'E. Morvant, “Adaptation de domaine de vote de majorité par auto-étiquetage
non itératif,” presented at the CAP: Conférence Francophone sur l’Apprentissage
Automatique (Machine Learning French Conference), Saint-Etienne, France, 2014,
vol. 1, pp. 49–58.'
ista: 'Morvant E. 2014. Adaptation de domaine de vote de majorité par auto-étiquetage
non itératif. CAP: Conférence Francophone sur l’Apprentissage Automatique (Machine
Learning French Conference) vol. 1, 49–58.'
mla: Morvant, Emilie. Adaptation de Domaine de Vote de Majorité Par Auto-Étiquetage
Non Itératif. Vol. 1, Elsevier, 2014, pp. 49–58.
short: E. Morvant, in:, Elsevier, 2014, pp. 49–58.
conference:
location: Saint-Etienne, France
name: 'CAP: Conférence Francophone sur l''Apprentissage Automatique (Machine Learning
French Conference)'
corr_author: '1'
date_created: 2018-12-11T11:56:13Z
date_published: 2014-07-01T00:00:00Z
date_updated: 2024-10-09T20:55:32Z
day: '01'
department:
- _id: ChLa
intvolume: ' 1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://hal.archives-ouvertes.fr/hal-01005776/
month: '07'
oa: 1
oa_version: Preprint
page: 49-58
publication_status: published
publisher: Elsevier
publist_id: '4785'
quality_controlled: '1'
status: public
title: Adaptation de domaine de vote de majorité par auto-étiquetage non itératif
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1
year: '2014'
...
---
_id: '2190'
abstract:
- lang: eng
text: We present a new algorithm to construct a (generalized) deterministic Rabin
automaton for an LTL formula φ. The automaton is the product of a master automaton
and an array of slave automata, one for each G-subformula of φ. The slave automaton
for G ψ is in charge of recognizing whether FG ψ holds. As opposed to standard
determinization procedures, the states of all our automata have a clear logical
structure, which allows for various optimizations. Our construction subsumes former
algorithms for fragments of LTL. Experimental results show improvement in the
sizes of the resulting automata compared to existing methods.
acknowledgement: The author is on leave from Faculty of Informatics, Masaryk University,
Czech Republic, and partially supported by the Czech Science Foundation, grant No.
P202/12/G061.
alternative_title:
- LNCS
article_processing_charge: No
arxiv: 1
author:
- first_name: Javier
full_name: Esparza, Javier
last_name: Esparza
- first_name: Jan
full_name: Kretinsky, Jan
id: 44CEF464-F248-11E8-B48F-1D18A9856A87
last_name: Kretinsky
orcid: 0000-0002-8122-2881
citation:
ama: 'Esparza J, Kretinsky J. From LTL to deterministic automata: A safraless compositional
approach. In: Vol 8559. Springer; 2014:192-208. doi:10.1007/978-3-319-08867-9_13'
apa: 'Esparza, J., & Kretinsky, J. (2014). From LTL to deterministic automata:
A safraless compositional approach (Vol. 8559, pp. 192–208). Presented at the
CAV: Computer Aided Verification, Springer. https://doi.org/10.1007/978-3-319-08867-9_13'
chicago: 'Esparza, Javier, and Jan Kretinsky. “From LTL to Deterministic Automata:
A Safraless Compositional Approach,” 8559:192–208. Springer, 2014. https://doi.org/10.1007/978-3-319-08867-9_13.'
ieee: 'J. Esparza and J. Kretinsky, “From LTL to deterministic automata: A safraless
compositional approach,” presented at the CAV: Computer Aided Verification, 2014,
vol. 8559, pp. 192–208.'
ista: 'Esparza J, Kretinsky J. 2014. From LTL to deterministic automata: A safraless
compositional approach. CAV: Computer Aided Verification, LNCS, vol. 8559, 192–208.'
mla: 'Esparza, Javier, and Jan Kretinsky. From LTL to Deterministic Automata:
A Safraless Compositional Approach. Vol. 8559, Springer, 2014, pp. 192–208,
doi:10.1007/978-3-319-08867-9_13.'
short: J. Esparza, J. Kretinsky, in:, Springer, 2014, pp. 192–208.
conference:
name: 'CAV: Computer Aided Verification'
corr_author: '1'
date_created: 2018-12-11T11:56:14Z
date_published: 2014-01-01T00:00:00Z
date_updated: 2025-06-11T08:01:04Z
day: '01'
department:
- _id: ToHe
- _id: KrCh
doi: 10.1007/978-3-319-08867-9_13
ec_funded: 1
external_id:
arxiv:
- '1402.3388'
intvolume: ' 8559'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1402.3388
month: '01'
oa: 1
oa_version: Submitted Version
page: 192 - 208
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25F5A88A-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11402-N23
name: Moderne Concurrency Paradigms
publication_status: published
publisher: Springer
publist_id: '4784'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'From LTL to deterministic automata: A safraless compositional approach'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8559
year: '2014'
...
---
_id: '1375'
abstract:
- lang: eng
text: 'We consider directed graphs where each edge is labeled with an integer weight
and study the fundamental algorithmic question of computing the value of a cycle
with minimum mean weight. Our contributions are twofold: (1) First we show that
the algorithmic question is reducible to the problem of a logarithmic number of
min-plus matrix multiplications of n×n-matrices, where n is the number of vertices
of the graph. (2) Second, when the weights are nonnegative, we present the first
(1+ε)-approximation algorithm for the problem and the running time of our algorithm
is Õ(nωlog3(nW/ε)/ε),1 where O(nω) is the time required for the classic n×n-matrix
multiplication and W is the maximum value of the weights. With an additional O(log(nW/ε))
factor in space a cycle with approximately optimal weight can be computed within
the same time bound.'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Sebastian
full_name: Krinninger, Sebastian
last_name: Krinninger
- first_name: Veronika
full_name: Loitzenbauer, Veronika
last_name: Loitzenbauer
- first_name: Michael
full_name: Raskin, Michael
last_name: Raskin
citation:
ama: Chatterjee K, Henzinger M, Krinninger S, Loitzenbauer V, Raskin M. Approximating
the minimum cycle mean. Theoretical Computer Science. 2014;547(C):104-116.
doi:10.1016/j.tcs.2014.06.031
apa: Chatterjee, K., Henzinger, M., Krinninger, S., Loitzenbauer, V., & Raskin,
M. (2014). Approximating the minimum cycle mean. Theoretical Computer Science.
Elsevier. https://doi.org/10.1016/j.tcs.2014.06.031
chicago: Chatterjee, Krishnendu, Monika Henzinger, Sebastian Krinninger, Veronika
Loitzenbauer, and Michael Raskin. “Approximating the Minimum Cycle Mean.” Theoretical
Computer Science. Elsevier, 2014. https://doi.org/10.1016/j.tcs.2014.06.031.
ieee: K. Chatterjee, M. Henzinger, S. Krinninger, V. Loitzenbauer, and M. Raskin,
“Approximating the minimum cycle mean,” Theoretical Computer Science, vol.
547, no. C. Elsevier, pp. 104–116, 2014.
ista: Chatterjee K, Henzinger M, Krinninger S, Loitzenbauer V, Raskin M. 2014. Approximating
the minimum cycle mean. Theoretical Computer Science. 547(C), 104–116.
mla: Chatterjee, Krishnendu, et al. “Approximating the Minimum Cycle Mean.” Theoretical
Computer Science, vol. 547, no. C, Elsevier, 2014, pp. 104–16, doi:10.1016/j.tcs.2014.06.031.
short: K. Chatterjee, M. Henzinger, S. Krinninger, V. Loitzenbauer, M. Raskin, Theoretical
Computer Science 547 (2014) 104–116.
date_created: 2018-12-11T11:51:40Z
date_published: 2014-08-28T00:00:00Z
date_updated: 2025-09-29T13:17:21Z
day: '28'
department:
- _id: KrCh
doi: 10.1016/j.tcs.2014.06.031
ec_funded: 1
external_id:
arxiv:
- '1307.4473'
isi:
- '000340694000008'
intvolume: ' 547'
isi: 1
issue: C
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1307.4473
month: '08'
oa: 1
oa_version: Preprint
page: 104 - 116
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
publication: Theoretical Computer Science
publication_status: published
publisher: Elsevier
publist_id: '5836'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Approximating the minimum cycle mean
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 547
year: '2014'
...
---
_id: '1392'
abstract:
- lang: eng
text: Fault-tolerant distributed algorithms play an important role in ensuring the
reliability of many software applications. In this paper we consider distributed
algorithms whose computations are organized in rounds. To verify the correctness
of such algorithms, we reason about (i) properties (such as invariants) of the
state, (ii) the transitions controlled by the algorithm, and (iii) the communication
graph. We introduce a logic that addresses these points, and contains set comprehensions
with cardinality constraints, function symbols to describe the local states of
each process, and a limited form of quantifier alternation to express the verification
conditions. We show its use in automating the verification of consensus algorithms.
In particular, we give a semi-decision procedure for the unsatisfiability problem
of the logic and identify a decidable fragment. We successfully applied our framework
to verify the correctness of a variety of consensus algorithms tolerant to both
benign faults (message loss, process crashes) and value faults (message corruption).
acknowledgement: Supported by the Vienna Science and Technology Fund (WWTF) through
grant PROSEED.
alternative_title:
- LNCS
author:
- first_name: Cezara
full_name: Dragoi, Cezara
id: 2B2B5ED0-F248-11E8-B48F-1D18A9856A87
last_name: Dragoi
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Helmut
full_name: Veith, Helmut
last_name: Veith
- first_name: Josef
full_name: Widder, Josef
last_name: Widder
- first_name: Damien
full_name: Zufferey, Damien
id: 4397AC76-F248-11E8-B48F-1D18A9856A87
last_name: Zufferey
orcid: 0000-0002-3197-8736
citation:
ama: 'Dragoi C, Henzinger TA, Veith H, Widder J, Zufferey D. A logic-based framework
for verifying consensus algorithms. In: Vol 8318. Springer; 2014:161-181. doi:10.1007/978-3-642-54013-4_10'
apa: 'Dragoi, C., Henzinger, T. A., Veith, H., Widder, J., & Zufferey, D. (2014).
A logic-based framework for verifying consensus algorithms (Vol. 8318, pp. 161–181).
Presented at the VMCAI: Verification, Model Checking and Abstract Interpretation,
San Diego, USA: Springer. https://doi.org/10.1007/978-3-642-54013-4_10'
chicago: Dragoi, Cezara, Thomas A Henzinger, Helmut Veith, Josef Widder, and Damien
Zufferey. “A Logic-Based Framework for Verifying Consensus Algorithms,” 8318:161–81.
Springer, 2014. https://doi.org/10.1007/978-3-642-54013-4_10.
ieee: 'C. Dragoi, T. A. Henzinger, H. Veith, J. Widder, and D. Zufferey, “A logic-based
framework for verifying consensus algorithms,” presented at the VMCAI: Verification,
Model Checking and Abstract Interpretation, San Diego, USA, 2014, vol. 8318, pp.
161–181.'
ista: 'Dragoi C, Henzinger TA, Veith H, Widder J, Zufferey D. 2014. A logic-based
framework for verifying consensus algorithms. VMCAI: Verification, Model Checking
and Abstract Interpretation, LNCS, vol. 8318, 161–181.'
mla: Dragoi, Cezara, et al. A Logic-Based Framework for Verifying Consensus Algorithms.
Vol. 8318, Springer, 2014, pp. 161–81, doi:10.1007/978-3-642-54013-4_10.
short: C. Dragoi, T.A. Henzinger, H. Veith, J. Widder, D. Zufferey, in:, Springer,
2014, pp. 161–181.
conference:
end_date: 2014-01-21
location: San Diego, USA
name: 'VMCAI: Verification, Model Checking and Abstract Interpretation'
start_date: 2014-01-19
date_created: 2018-12-11T11:51:45Z
date_published: 2014-01-01T00:00:00Z
date_updated: 2021-01-12T06:50:22Z
day: '01'
ddc:
- '000'
- '005'
department:
- _id: ToHe
doi: 10.1007/978-3-642-54013-4_10
ec_funded: 1
file:
- access_level: open_access
checksum: bffa33d39be77df0da39defe97eabf84
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:11:06Z
date_updated: 2020-07-14T12:44:48Z
file_id: '4859'
file_name: IST-2014-179-v1+1_vmcai14.pdf
file_size: 444138
relation: main_file
file_date_updated: 2020-07-14T12:44:48Z
has_accepted_license: '1'
intvolume: ' 8318'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Submitted Version
page: 161 - 181
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
publication_status: published
publisher: Springer
publist_id: '5817'
pubrep_id: '179'
quality_controlled: '1'
scopus_import: 1
status: public
title: A logic-based framework for verifying consensus algorithms
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8318
year: '2014'
...
---
_id: '1393'
abstract:
- lang: eng
text: 'Probabilistic programs are usual functional or imperative programs with two
added constructs: (1) the ability to draw values at random from distributions,
and (2) the ability to condition values of variables in a program via observations.
Models from diverse application areas such as computer vision, coding theory,
cryptographic protocols, biology and reliability analysis can be written as probabilistic
programs. Probabilistic inference is the problem of computing an explicit representation
of the probability distribution implicitly specified by a probabilistic program.
Depending on the application, the desired output from inference may vary-we may
want to estimate the expected value of some function f with respect to the distribution,
or the mode of the distribution, or simply a set of samples drawn from the distribution.
In this paper, we describe connections this research area called \Probabilistic
Programming" has with programming languages and software engineering, and
this includes language design, and the static and dynamic analysis of programs.
We survey current state of the art and speculate on promising directions for future
research.'
article_processing_charge: No
author:
- first_name: Andrew
full_name: Gordon, Andrew
last_name: Gordon
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Aditya
full_name: Nori, Aditya
last_name: Nori
- first_name: Sriram
full_name: Rajamani, Sriram
last_name: Rajamani
citation:
ama: 'Gordon A, Henzinger TA, Nori A, Rajamani S. Probabilistic programming. In:
Proceedings of the on Future of Software Engineering. ACM; 2014:167-181.
doi:10.1145/2593882.2593900'
apa: 'Gordon, A., Henzinger, T. A., Nori, A., & Rajamani, S. (2014). Probabilistic
programming. In Proceedings of the on Future of Software Engineering (pp.
167–181). Hyderabad, India: ACM. https://doi.org/10.1145/2593882.2593900'
chicago: Gordon, Andrew, Thomas A Henzinger, Aditya Nori, and Sriram Rajamani. “Probabilistic
Programming.” In Proceedings of the on Future of Software Engineering,
167–81. ACM, 2014. https://doi.org/10.1145/2593882.2593900.
ieee: A. Gordon, T. A. Henzinger, A. Nori, and S. Rajamani, “Probabilistic programming,”
in Proceedings of the on Future of Software Engineering, Hyderabad, India,
2014, pp. 167–181.
ista: 'Gordon A, Henzinger TA, Nori A, Rajamani S. 2014. Probabilistic programming.
Proceedings of the on Future of Software Engineering. FOSE: Future of Software
Engineering, 167–181.'
mla: Gordon, Andrew, et al. “Probabilistic Programming.” Proceedings of the on
Future of Software Engineering, ACM, 2014, pp. 167–81, doi:10.1145/2593882.2593900.
short: A. Gordon, T.A. Henzinger, A. Nori, S. Rajamani, in:, Proceedings of the
on Future of Software Engineering, ACM, 2014, pp. 167–181.
conference:
end_date: 2014-06-07
location: Hyderabad, India
name: 'FOSE: Future of Software Engineering'
start_date: 2014-05-31
date_created: 2018-12-11T11:51:45Z
date_published: 2014-05-31T00:00:00Z
date_updated: 2026-06-18T17:31:28Z
day: '31'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.1145/2593882.2593900
ec_funded: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1145/2593882.2593900
month: '05'
oa: 1
oa_version: Published Version
page: 167 - 181
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
publication: Proceedings of the on Future of Software Engineering
publication_status: published
publisher: ACM
publist_id: '5816'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Probabilistic programming
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2014'
...
---
OA_place: publisher
_id: '1395'
abstract:
- lang: eng
text: In this thesis I studied various individual and social immune defences employed
by the invasive garden ant Lasius neglectus mostly against entomopathogenic fungi. The
first two chapters of this thesis address the phenomenon of 'social immunisation'.
Social immunisation, that is the immunological protection of group members due
to social contact to a pathogen-exposed nestmate, has been described in various
social insect species against different types of pathogens. However, in the case
of entomopathogenic fungi it has, so far, only been demonstrated that social immunisation
exists at all. Its underlying mechanisms r any other properties were, however,
unknown. In the first chapter of this thesis I identified the mechanistic basis
of social immunisation in L. neglectus against the entomopathogenous fungus Metarhizium.
I could show that nestmates of a pathogen-exposed individual contract low-level
infections due to social interactions. These low-level infections are, however,
non-lethal and cause an active stimulation of the immune system, which protects
the nestmates upon subsequent pathogen encounters. In the second chapter of this
thesis I investigated the specificity and colony level effects of social immunisation.
I demonstrated that the protection conferred by social immunisation is highly
specific, protecting ants only against the same pathogen strain. In addition,
depending on the respective context, social immunisation may even cause fitness
costs. I further showed that social immunisation crucially affects sanitary behaviour
and disease dynamics within ant groups. In the third chapter of this thesis I
studied the effects of the ectosymbiotic fungus Laboulbenia formicarum on its
host L. neglectus. Although Laboulbeniales are the largest order of insect-parasitic
fungi, research concerning host fitness consequence is sparse. I showed that highly
Laboulbenia-infected ants sustain fitness costs under resource limitation, however,
gain fitness benefits when exposed to an entomopathogenus fungus. These effects
are probably cause by a prophylactic upregulation of behavioural as well as physiological
immune defences in highly infected ants.
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Matthias
full_name: Konrad, Matthias
id: 46528076-F248-11E8-B48F-1D18A9856A87
last_name: Konrad
citation:
ama: 'Konrad M. Immune defences in ants: Effects of social immunisation and a fungal
ectosymbiont in the ant Lasius neglectus. 2014.'
apa: 'Konrad, M. (2014). Immune defences in ants: Effects of social immunisation
and a fungal ectosymbiont in the ant Lasius neglectus. Institute of Science
and Technology Austria.'
chicago: 'Konrad, Matthias. “Immune Defences in Ants: Effects of Social Immunisation
and a Fungal Ectosymbiont in the Ant Lasius Neglectus.” Institute of Science and
Technology Austria, 2014.'
ieee: 'M. Konrad, “Immune defences in ants: Effects of social immunisation and a
fungal ectosymbiont in the ant Lasius neglectus,” Institute of Science and Technology
Austria, 2014.'
ista: 'Konrad M. 2014. Immune defences in ants: Effects of social immunisation and
a fungal ectosymbiont in the ant Lasius neglectus. Institute of Science and Technology
Austria.'
mla: 'Konrad, Matthias. Immune Defences in Ants: Effects of Social Immunisation
and a Fungal Ectosymbiont in the Ant Lasius Neglectus. Institute of Science
and Technology Austria, 2014.'
short: 'M. Konrad, Immune Defences in Ants: Effects of Social Immunisation and a
Fungal Ectosymbiont in the Ant Lasius Neglectus, Institute of Science and Technology
Austria, 2014.'
corr_author: '1'
date_created: 2018-12-11T11:51:46Z
date_published: 2014-02-01T00:00:00Z
date_updated: 2026-04-09T14:27:01Z
day: '01'
degree_awarded: PhD
department:
- _id: SyCr
language:
- iso: eng
month: '02'
oa_version: None
page: '131'
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '5814'
status: public
supervisor:
- first_name: Sylvia M
full_name: Cremer, Sylvia M
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
title: 'Immune defences in ants: Effects of social immunisation and a fungal ectosymbiont
in the ant Lasius neglectus'
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2014'
...
---
OA_place: publisher
_id: '1402'
abstract:
- lang: eng
text: Phosphatidylinositol (Ptdlns) is a structural phospholipid that can be phosphorylated
into various lipid signaling molecules, designated polyphosphoinositides (PPIs).
The reversible phosphorylation of PPIs on the 3, 4, or 5 position of inositol
is performed by a set of organelle-specific kinases and phosphatases, and the
characteristic head groups make these molecules ideal for regulating biological
processes in time and space. In yeast and mammals, Ptdlns3P and Ptdlns(3,5)P2
play crucial roles in trafficking toward the lytic compartments, whereas the role
in plants is not yet fully understood. Here we identified the role of a land plant-specific
subgroup of PPI phosphatases, the suppressor of actin 2 (SAC2) to SAC5, during
vauolar trafficking and morphogenesis in Arabidopsis thaliana. SAC2-SAC5 localize
to the tonoplast along with Ptdlns3P, the presumable product of their activity.
in SAC gain- and loss-of-function mutants, the levels of Ptdlns monophosphates
and bisphosphates were changed, with opposite effects on the morphology of storage
and lytic vacuoles, and the trafficking toward the vacuoles was defective. Moreover,
multiple sac knockout mutants had an increased number of smaller storage and lytic
vacuoles, whereas extralarge vacuoles were observed in the overexpression lines,
correlating with various growth and developmental defects. The fragmented vacuolar
phenotype of sac mutants could be mimicked by treating wild-type seedlings with
Ptdlns(3,5)P2, corroborating that this PPI is important for vacuole morphology.
Taken together, these results provide evidence that PPIs, together with their
metabolic enzymes SAC2-SAC5, are crucial for vacuolar trafficking and for vacuolar
morphology and function in plants.
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Petra
full_name: Marhavá, Petra
id: 44E59624-F248-11E8-B48F-1D18A9856A87
last_name: Marhavá
citation:
ama: Marhavá P. Molecular mechanisms of patterning and subcellular trafficking in
Arabidopsis thaliana. 2014.
apa: Marhavá, P. (2014). Molecular mechanisms of patterning and subcellular trafficking
in Arabidopsis thaliana. Institute of Science and Technology Austria.
chicago: Marhavá, Petra. “Molecular Mechanisms of Patterning and Subcellular Trafficking
in Arabidopsis Thaliana.” Institute of Science and Technology Austria, 2014.
ieee: P. Marhavá, “Molecular mechanisms of patterning and subcellular trafficking
in Arabidopsis thaliana,” Institute of Science and Technology Austria, 2014.
ista: Marhavá P. 2014. Molecular mechanisms of patterning and subcellular trafficking
in Arabidopsis thaliana. Institute of Science and Technology Austria.
mla: Marhavá, Petra. Molecular Mechanisms of Patterning and Subcellular Trafficking
in Arabidopsis Thaliana. Institute of Science and Technology Austria, 2014.
short: P. Marhavá, Molecular Mechanisms of Patterning and Subcellular Trafficking
in Arabidopsis Thaliana, Institute of Science and Technology Austria, 2014.
corr_author: '1'
date_created: 2018-12-11T11:51:49Z
date_published: 2014-12-01T00:00:00Z
date_updated: 2026-04-09T14:27:28Z
day: '01'
degree_awarded: PhD
department:
- _id: JiFr
language:
- iso: eng
month: '12'
oa_version: None
page: '90'
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '5805'
status: public
supervisor:
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
title: Molecular mechanisms of patterning and subcellular trafficking in Arabidopsis
thaliana
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2014'
...
---
OA_place: repository
_id: '1403'
abstract:
- lang: eng
text: A variety of developmental and disease related processes depend on epithelial
cell sheet spreading. In order to gain insight into the biophysical mechanism(s)
underlying the tissue morphogenesis we studied the spreading of an epithelium
during the early development of the zebrafish embryo. In zebrafish epiboly the
enveloping cell layer (EVL), a simple squamous epithelium, spreads over the yolk
cell to completely engulf it at the end of gastrulation. Previous studies have
proposed that an actomyosin ring forming within the yolk syncytial layer (YSL)
acts as purse string that through constriction along its circumference pulls on
the margin of the EVL. Direct biophysical evidence for this hypothesis has however
been missing. The aim of the thesis was to understand how the actomyosin ring
may generate pulling forces onto the EVL and what cellular mechanism(s) may facilitate
the spreading of the epithelium. Using laser ablation to measure cortical tension
within the actomyosin ring we found an anisotropic tension distribution, which
was highest along the circumference of the ring. However the low degree of anisotropy
was incompatible with the actomyosin ring functioning as a purse string only.
Additionally, we observed retrograde cortical flow from vegetal parts of the ring
into the EVL margin. Interpreting the experimental data using a theoretical distribution
that models the tissues as active viscous gels led us to proposen that the actomyosin
ring has a twofold contribution to EVL epiboly. It not only acts as a purse string
through constriction along its circumference, but in addition constriction along
the width of the ring generates pulling forces through friction-resisted cortical
flow. Moreover, when rendering the purse string mechanism unproductive EVL epiboly
proceeded normally indicating that the flow-friction mechanism is sufficient to
drive the process. Aiming to understand what cellular mechanism(s) may facilitate
the spreading of the epithelium we found that tension-oriented EVL cell divisions
limit tissue anisotropy by releasing tension along the division axis and promote
epithelial spreading. Notably, EVL cells undergo ectopic cell fusion in conditions
in which oriented-cell division is impaired or the epithelium is mechanically
challenged. Taken together our study of EVL epiboly suggests a novel mechanism
of force generation for actomyosin rings through friction-resisted cortical flow
and highlights the importance of tension-oriented cell divisions in epithelial
morphogenesis.
acknowledged_ssus:
- _id: SSU
alternative_title:
- IST Austria Thesis
article_processing_charge: No
author:
- first_name: Martin
full_name: Behrndt, Martin
id: 3ECECA3A-F248-11E8-B48F-1D18A9856A87
last_name: Behrndt
citation:
ama: Behrndt M. Forces driving epithelial spreading in zebrafish epiboly. 2014.
apa: Behrndt, M. (2014). Forces driving epithelial spreading in zebrafish epiboly.
IST Austria.
chicago: Behrndt, Martin. “Forces Driving Epithelial Spreading in Zebrafish Epiboly.”
IST Austria, 2014.
ieee: M. Behrndt, “Forces driving epithelial spreading in zebrafish epiboly,” IST
Austria, 2014.
ista: Behrndt M. 2014. Forces driving epithelial spreading in zebrafish epiboly.
IST Austria.
mla: Behrndt, Martin. Forces Driving Epithelial Spreading in Zebrafish Epiboly.
IST Austria, 2014.
short: M. Behrndt, Forces Driving Epithelial Spreading in Zebrafish Epiboly, IST
Austria, 2014.
corr_author: '1'
date_created: 2018-12-11T11:51:49Z
date_published: 2014-08-01T00:00:00Z
date_updated: 2026-06-18T18:45:01Z
day: '01'
ddc:
- '590'
degree_awarded: PhD
department:
- _id: CaHe
file:
- access_level: closed
checksum: 67df5501b1b5b313c3bf9a360d713693
content_type: application/pdf
creator: cchlebak
date_created: 2026-03-09T14:53:14Z
date_updated: 2026-03-09T14:53:14Z
file_id: '21421'
file_name: 2014 Behrnd final.pdf
file_size: 24842978
relation: main_file
file_date_updated: 2026-03-09T14:53:14Z
has_accepted_license: '1'
language:
- iso: eng
month: '08'
oa_version: None
page: '91'
publication_status: published
publisher: IST Austria
publist_id: '5804'
related_material:
record:
- id: '2282'
relation: part_of_dissertation
status: public
- id: '2950'
relation: part_of_dissertation
status: public
- id: '3373'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
title: Forces driving epithelial spreading in zebrafish epiboly
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2014'
...
---
OA_place: publisher
_id: '1404'
abstract:
- lang: eng
text: "The co-evolution of hosts and pathogens is characterized by continuous adaptations
of both parties. Pathogens of social insects need to adapt towards disease defences
at two levels: 1) individual immunity of each colony member consisting of behavioural
defence strategies as well as humoral and cellular immune responses and 2) social
immunity that is collectively performed by all group members comprising behavioural,
physiological and organisational defence strategies.\r\n\r\nTo disentangle the
selection pressure on pathogens by the collective versus individual level of disease
defence in social insects, we performed an evolution experiment using the Argentine
Ant, Linepithema humile, as a host and a mixture of the general insect pathogenic
fungus Metarhizium spp. (6 strains) as a pathogen. We allowed pathogen evolution
over 10 serial host passages to two different evolution host treatments: (1) only
individual host immunity in a single host treatment, and (2) simultaneously acting
individual and social immunity in a social host treatment, in which an exposed
ant was accompanied by two untreated nestmates.\r\n\r\nBefore starting the pathogen
evolution experiment, the 6 Metarhizium spp. strains were characterised concerning
conidiospore size killing rates in singly and socially reared ants, their competitiveness
under coinfecting conditions and their influence on ant behaviour. We analysed
how the ancestral atrain mixture changed in conidiospere size, killing rate and
strain composition dependent on host treatment (single or social hosts) during
10 passages and found that killing rate and conidiospere size of the pathogen
increased under both evolution regimes, but different depending on host treatment.\r\n\r\nTesting
the evolved strain mixtures that evolved under either the single or social host
treatment under both single and social current rearing conditions in a full factorial
design experiment revealed that the additional collective defences in insect societies
add new selection pressure for their coevolving pathogens that compromise their
ability to adapt to its host at the group level. To our knowledge, this is the
first study directly measuring the influence of social immunity on pathogen evolution."
acknowledgement: This work was funded by the DFG and the ERC.
alternative_title:
- IST Austria Thesis
article_processing_charge: No
author:
- first_name: Miriam
full_name: Stock, Miriam
id: 42462816-F248-11E8-B48F-1D18A9856A87
last_name: Stock
citation:
ama: Stock M. Evolution of a fungal pathogen towards individual versus social immunity
in ants. 2014.
apa: Stock, M. (2014). Evolution of a fungal pathogen towards individual versus
social immunity in ants. IST Austria.
chicago: Stock, Miriam. “Evolution of a Fungal Pathogen towards Individual versus
Social Immunity in Ants.” IST Austria, 2014.
ieee: M. Stock, “Evolution of a fungal pathogen towards individual versus social
immunity in ants,” IST Austria, 2014.
ista: Stock M. 2014. Evolution of a fungal pathogen towards individual versus social
immunity in ants. IST Austria.
mla: Stock, Miriam. Evolution of a Fungal Pathogen towards Individual versus
Social Immunity in Ants. IST Austria, 2014.
short: M. Stock, Evolution of a Fungal Pathogen towards Individual versus Social
Immunity in Ants, IST Austria, 2014.
corr_author: '1'
date_created: 2018-12-11T11:51:49Z
date_published: 2014-04-01T00:00:00Z
date_updated: 2026-04-09T14:33:27Z
day: '01'
department:
- _id: SyCr
language:
- iso: eng
month: '04'
oa_version: None
page: '101'
publication_status: published
publisher: IST Austria
publist_id: '5803'
status: public
supervisor:
- first_name: Sylvia M
full_name: Cremer, Sylvia M
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
title: Evolution of a fungal pathogen towards individual versus social immunity in
ants
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2014'
...