[{"department":[{"_id":"JiFr"}],"acknowledgement":"We thank Dr. Z. Ge (ISTA) for providing vectors for the CRISPR-Cas9 system, Dr. Armel Nicolas and Dr. Bella Bruszel for phosphoproteomic analysis, Prof. Michael Wrzaczek (Czech Academy of Sciences, Czechia) for valuable suggestions, and Prof. Maciek Adamowski (University of Gdańsk) for technical assistance. We also acknowledge the support of the Mass Spectrometry and Proteomics Facility, the Imaging & Optics Facility, and the Lab Support Facility at the Institute of Science and Technology Austria. This research was supported by the Scientific Service Units (SSU) of ISTA, utilizing resources provided by the Imaging & Optics Facility (IOF) and the Lab Support Facility (LSF). The work conducted by the Friml group was funded by the European Research Council (ERC) under grant agreement no. 101142681 (CYNIPS) and by the Austrian Science Fund (FWF) under project ESP271. We acknowledge the core facility CELLIM supported by MEYS CR (LM2023050 Czech-BioImaging) and the Plant Sciences Core Facility of CEITEC Masaryk University. E.M. received support from the National Science Centre (NCN), Poland, through the OPUS call within the Weave programme (grant no. 2021/43/I/NZ1/01835). T.N. received support from TowArds Next GENeration Crops, reg. no. CZ.02.01.01/00/22_008/0004581 of the ERDF Programme Johannes Amos Comenius.","OA_place":"publisher","acknowledged_ssus":[{"_id":"MassSpec"},{"_id":"Bio"},{"_id":"LifeSc"}],"author":[{"last_name":"Li","first_name":"Mingyue","full_name":"Li, Mingyue","id":"01f96916-0235-11eb-9379-a323192643b7"},{"last_name":"Rydza","first_name":"Nikola","full_name":"Rydza, Nikola"},{"full_name":"Mazur, Ewa","first_name":"Ewa","last_name":"Mazur"},{"first_name":"Gergely","last_name":"Molnar","full_name":"Molnar, Gergely","id":"34F1AF46-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Nodzyński","first_name":"Tomasz","full_name":"Nodzyński, Tomasz"},{"orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml","first_name":"Jiří","full_name":"Friml, Jiří"}],"PlanS_conform":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"ddc":["580"],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","language":[{"iso":"eng"}],"publication":"Current Biology","intvolume":"        36","issue":"6","citation":{"apa":"Li, M., Rydza, N., Mazur, E., Molnar, G., Nodzyński, T., &#38; Friml, J. (2026). Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin canalization. <i>Current Biology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.cub.2026.02.023\">https://doi.org/10.1016/j.cub.2026.02.023</a>","mla":"Li, Mingyue, et al. “Receptor-like-Kinase-Interacting Protein TOW Stabilizes PIN Transporters for Auxin Canalization.” <i>Current Biology</i>, vol. 36, no. 6, Elsevier, 2026, p. 1468–1480.e6, doi:<a href=\"https://doi.org/10.1016/j.cub.2026.02.023\">10.1016/j.cub.2026.02.023</a>.","chicago":"Li, Mingyue, Nikola Rydza, Ewa Mazur, Gergely Molnar, Tomasz Nodzyński, and Jiří Friml. “Receptor-like-Kinase-Interacting Protein TOW Stabilizes PIN Transporters for Auxin Canalization.” <i>Current Biology</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.cub.2026.02.023\">https://doi.org/10.1016/j.cub.2026.02.023</a>.","ieee":"M. Li, N. Rydza, E. Mazur, G. Molnar, T. Nodzyński, and J. Friml, “Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin canalization,” <i>Current Biology</i>, vol. 36, no. 6. Elsevier, p. 1468–1480.e6, 2026.","ista":"Li M, Rydza N, Mazur E, Molnar G, Nodzyński T, Friml J. 2026. Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin canalization. Current Biology. 36(6), 1468–1480.e6.","ama":"Li M, Rydza N, Mazur E, Molnar G, Nodzyński T, Friml J. Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin canalization. <i>Current Biology</i>. 2026;36(6):1468-1480.e6. doi:<a href=\"https://doi.org/10.1016/j.cub.2026.02.023\">10.1016/j.cub.2026.02.023</a>","short":"M. Li, N. Rydza, E. Mazur, G. Molnar, T. Nodzyński, J. Friml, Current Biology 36 (2026) 1468–1480.e6."},"file":[{"date_created":"2026-03-24T08:34:37Z","file_name":"2026_CurrentBiology_Li.pdf","creator":"dernst","file_id":"21496","content_type":"application/pdf","success":1,"date_updated":"2026-03-24T08:34:37Z","file_size":12986894,"access_level":"open_access","relation":"main_file","checksum":"fe6c41fdab58a55df5f2a5860c02acdc"}],"publisher":"Elsevier","article_processing_charge":"Yes (via OA deal)","day":"23","date_published":"2026-03-23T00:00:00Z","file_date_updated":"2026-03-24T08:34:37Z","external_id":{"pmid":["41831441"]},"type":"journal_article","volume":36,"has_accepted_license":"1","doi":"10.1016/j.cub.2026.02.023","publication_identifier":{"issn":["0960-9822"]},"article_type":"original","month":"03","quality_controlled":"1","oa_version":"Published Version","date_updated":"2026-03-24T08:36:40Z","year":"2026","pmid":1,"project":[{"_id":"8f347782-16d5-11f0-9cad-8c19706ee739","name":"Cyclic nucleotides as second messengers in plants","grant_number":"101142681"},{"_id":"bd906599-d553-11ed-ba76-abf8547645d7","grant_number":"E271","name":"Identification of a novel regulator in auxin canalization"}],"OA_type":"hybrid","publication_status":"published","page":"1468-1480.e6","corr_author":"1","status":"public","_id":"21490","title":"Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin canalization","oa":1,"date_created":"2026-03-23T15:11:16Z","abstract":[{"text":"Auxin canalization is a self-organizing process that governs the flexible formation of vasculature by reinforcing the formation of auxin transport channels. A key prerequisite is the feedback between auxin signaling and directional auxin transport, mediated by PIN transporters. Despite the developmental importance of canalization, the molecular components linking auxin perception to the regulation of PIN auxin transporters remain poorly understood. Here, we identify TOW, a novel and essential component of auxin canalization that links intracellular auxin signaling with cell surface auxin perception. TOW is regulated downstream of TIR1/AFB-Aux/IAA-WRKY23 transcriptional auxin signaling. tow mutants exhibit defects in regeneration and de novo vasculature formation, along with impaired formation of polarized, PIN-expressing auxin channels. At the subcellular level, these mutants display disrupted auxin-induced PIN polarization and altered PIN endocytic trafficking dynamics. TOW localizes predominantly to the plasma membrane, where it interacts with receptor-like kinases involved in auxin canalization, including the TMK1 auxin co-receptor and the CAMEL-CANAR complex. TOW promotes PIN interaction with these kinases and stabilizes PINs at the cell surface. Together, our findings identify TOW as a molecular link between intracellular and cell surface auxin signaling mechanisms that converge on PIN trafficking and polarity, providing new insights into how auxin signaling regulates directional auxin transport for the self-organizing formation of vasculature during flexible plant development.","lang":"eng"}]},{"abstract":[{"lang":"eng","text":"Pyridyl motifs equipped with N-substituents can be powerful ligands for catalysis, yet their broader adoption is limited by the lack of a practical method to prepare these scaffolds. We report a modular, robust, and versatile Buchwald–Hartwig amination protocol that enables the rapid synthesis of bipyridine, phenanthroline, terpyridine, and pybox ligands bearing dialkylamine, diarylamine, and heteroaromatic N-substituents. These conditions streamline ligand library synthesis and will facilitate systematic studies in catalysis and related applications."}],"date_created":"2026-05-03T22:01:36Z","oa":1,"status":"public","_id":"21776","title":"Facile access to N-substituted pyridyl ligands","corr_author":"1","publication_status":"published","OA_type":"hybrid","year":"2026","project":[{"_id":"8f1d607d-16d5-11f0-9cad-ab453295ba5e","name":"Photoactive ligands for transformative nickel catalysis","grant_number":"PAT 1250924"}],"date_updated":"2026-05-07T07:33:33Z","scopus_import":"1","oa_version":"Published Version","article_type":"original","quality_controlled":"1","month":"05","publication_identifier":{"issn":["1615-4150"],"eissn":["1615-4169"]},"doi":"10.1002/adsc.70417","volume":368,"has_accepted_license":"1","type":"journal_article","date_published":"2026-05-05T00:00:00Z","day":"05","article_processing_charge":"Yes (via OA deal)","file_date_updated":"2026-05-07T07:29:24Z","article_number":"e70417","issue":"9","intvolume":"       368","file":[{"date_created":"2026-05-07T07:29:24Z","file_id":"21833","creator":"dernst","file_name":"2026_AdvSynthCatal_Petrik.pdf","file_size":437184,"access_level":"open_access","content_type":"application/pdf","date_updated":"2026-05-07T07:29:24Z","success":1,"relation":"main_file","checksum":"afe9752977898642c903abdc70b4a283"}],"publisher":"Wiley","citation":{"mla":"Petrik, Adam, et al. “Facile Access to N-Substituted Pyridyl Ligands.” <i>Advanced Synthesis &#38; Catalysis</i>, vol. 368, no. 9, e70417, Wiley, 2026, doi:<a href=\"https://doi.org/10.1002/adsc.70417\">10.1002/adsc.70417</a>.","apa":"Petrik, A., Bena, A., Baunis, H., Kelch, R. M., Yoon, T. P., &#38; Pieber, B. (2026). Facile access to N-substituted pyridyl ligands. <i>Advanced Synthesis &#38; Catalysis</i>. Wiley. <a href=\"https://doi.org/10.1002/adsc.70417\">https://doi.org/10.1002/adsc.70417</a>","short":"A. Petrik, A. Bena, H. Baunis, R.M. Kelch, T.P. Yoon, B. Pieber, Advanced Synthesis &#38; Catalysis 368 (2026).","ama":"Petrik A, Bena A, Baunis H, Kelch RM, Yoon TP, Pieber B. Facile access to N-substituted pyridyl ligands. <i>Advanced Synthesis &#38; Catalysis</i>. 2026;368(9). doi:<a href=\"https://doi.org/10.1002/adsc.70417\">10.1002/adsc.70417</a>","ista":"Petrik A, Bena A, Baunis H, Kelch RM, Yoon TP, Pieber B. 2026. Facile access to N-substituted pyridyl ligands. Advanced Synthesis &#38; Catalysis. 368(9), e70417.","ieee":"A. Petrik, A. Bena, H. Baunis, R. M. Kelch, T. P. Yoon, and B. Pieber, “Facile access to N-substituted pyridyl ligands,” <i>Advanced Synthesis &#38; Catalysis</i>, vol. 368, no. 9. Wiley, 2026.","chicago":"Petrik, Adam, Aleksander Bena, Haralds Baunis, Riley M. Kelch, Tehshik P. Yoon, and Bartholomäus Pieber. “Facile Access to N-Substituted Pyridyl Ligands.” <i>Advanced Synthesis &#38; Catalysis</i>. Wiley, 2026. <a href=\"https://doi.org/10.1002/adsc.70417\">https://doi.org/10.1002/adsc.70417</a>."},"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"PlanS_conform":"1","publication":"Advanced Synthesis & Catalysis","language":[{"iso":"eng"}],"ddc":["540"],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledgement":"We gratefully acknowledge ISTA for generous financial support. B.P. acknowledges the Austrian Science Fund (PAT 1250924) and the ACS GCI Pharmaceutical Roundtable for funding; T.P.Y acknowledges the NSF(CHE-2349003) for financial support. This research was supported by the Scientific Service Units (SSU) of ISTA through resources provided by the Lab Support Facility, Mass Spec Facility, NMR facility, and the Miba Machine Shop. We specifically thank Aikaterina Paraskevopoulou for HRMS measurements and Jan Pecak for support with ICP-OES experi-ments. NMR facilities at UW−Madison were supported by the NSF(CHE-1048642) and a generous gift from Paul J. and Margaret M. Bender. Open Access funding provided by Institute of Science and Technology Austria/KEMÖ. This study was supported by Austrian Science Fund (PAT 1250924), ACSGCI Pharmaceutical Roundtable, and National Science Foundation(CHE-2349003) and (CHE-1048642).","department":[{"_id":"BaPi"},{"_id":"GradSch"}],"author":[{"id":"e273d403-329f-11ee-a353-8c34c056f8ed","last_name":"Petrik","first_name":"Adam","full_name":"Petrik, Adam"},{"id":"4197c39e-e8ec-11ed-86cb-afed934cd664","first_name":"Aleksander","last_name":"Bena","full_name":"Bena, Aleksander"},{"full_name":"Baunis, Haralds","last_name":"Baunis","first_name":"Haralds","id":"2eea55ec-e8ec-11ed-86cb-d9c76787acfe"},{"last_name":"Kelch","first_name":"Riley M.","full_name":"Kelch, Riley M."},{"full_name":"Yoon, Tehshik P.","first_name":"Tehshik P.","last_name":"Yoon"},{"last_name":"Pieber","first_name":"Bartholomäus","full_name":"Pieber, Bartholomäus","orcid":"0000-0001-8689-388X","id":"93e5e5b2-0da6-11ed-8a41-af589a024726"}],"OA_place":"publisher","acknowledged_ssus":[{"_id":"LifeSc"},{"_id":"MassSpec"},{"_id":"NMR"},{"_id":"M-Shop"}]},{"scopus_import":"1","oa_version":"Published Version","date_updated":"2026-06-02T14:36:41Z","year":"2026","project":[{"grant_number":"101142681","name":"Cyclic nucleotides as second messengers in plants","_id":"8f347782-16d5-11f0-9cad-8c19706ee739"},{"name":"Guanylate cyclase activity of TIR1/AFBs auxin receptors","grant_number":"P37051","_id":"7bcece63-9f16-11ee-852c-ae94e099eeb6"}],"pmid":1,"OA_type":"gold","publication_status":"published","corr_author":"1","_id":"21914","status":"public","title":"Biogenesis and downstream effects of 3',5' and 2',3' cAMP isomers in plants","oa":1,"date_created":"2026-05-24T22:01:31Z","abstract":[{"text":"Cyclic adenosine monophosphate (cAMP) is a fundamental second messenger involved in diverse signaling pathways across both animals and plants. While the role of 3′,5′-cAMP has been extensively characterized, the biological significance of its structural isomer, 2′,3′-cAMP, remains largely unexplored, particularly in plants. Here, we show that 2′,3′-cAMP and 3′,5′-cAMP represent parallel signaling systems in Arabidopsis thaliana, with different enzymatic origins and largely distinct downstream effects. In vitro enzymatic assays show that plant adenylate cyclases (ACs), including AFB5 and HpAC1, produce specifically 3′,5′-cAMP from ATP, whereas the TIR domain of protein L7 also catalyzes the formation of 2′,3′-cAMP from RNA. Comprehensive multiomics analyses reveal that two isomers elicit distinct yet partially overlapping metabolic, proteomic, and transcriptional response: 2′,3′-cAMP activates broad, stress-adaptive gene expression reprogramming, while 3′,5′-cAMP fine-tunes responses related to nutrient status and cellular homeostasis. Our findings establish the existence of dual cAMP signaling systems in plants, each with specialized functions and provide insights into the complex regulatory networks governing plant physiology.","lang":"eng"}],"department":[{"_id":"JiFr"}],"acknowledgement":" We thank J. Chai and D. Yu for providing the MBP-fused L7TIR plasmid and K. Jaworski (Nicolaus Copernicus University) for the GST-­HpAC1 plasmid. We also thank M. Randuch and L. Fiedler for providing vectors for recombinant AFB5 and ADCY. We are also grateful to E. Dutkiewicz, L. Trübestein, N. Krasnici and A. Michaelis for excellent technical\r\nassistance. We acknowledge the support of the LSF Mass Spectrometry Service and the Lab\r\nSupport Facility at the Institute of Science and Technology Austria for their contributions,\r\nincluding consultation on size exclusion chromatography, LC/MS experimental design,\r\nmetabolomics sample preparation, LC/MS method optimization, data acquisition, raw data\r\nanalysis, and absolute quantification. This project is supported by the European\r\nResearch Council (ERC) under the European Union’s Horizon 2020 research and innovation\r\nprogram (101142681 CYNIPS) and Austrian Science Fund (FWF; P 37051-B), both to J.Friml.\r\nWe acknowledge the generous support of the Taif University Researchers Supporting\r\nProject: TURSP-­HC2022/02 and Max-Planck-Society to A.S. ","acknowledged_ssus":[{"_id":"MassSpec"},{"_id":"LifeSc"}],"OA_place":"publisher","author":[{"id":"01f96916-0235-11eb-9379-a323192643b7","full_name":"Li, Mingyue","last_name":"Li","first_name":"Mingyue"},{"first_name":"Monika","last_name":"Chodasiewicz","full_name":"Chodasiewicz, Monika"},{"full_name":"Muraleedharan, Malavika","first_name":"Malavika","last_name":"Muraleedharan"},{"full_name":"Lopez, Israel M.","last_name":"Lopez","first_name":"Israel M."},{"full_name":"Gorka, Michal","last_name":"Gorka","first_name":"Michal"},{"full_name":"Kerber, Olga","first_name":"Olga","last_name":"Kerber"},{"full_name":"Alotaibi, Saqer S.","last_name":"Alotaibi","first_name":"Saqer S."},{"full_name":"Nelson, Andrew D.L.","first_name":"Andrew D.L.","last_name":"Nelson"},{"full_name":"Lenobel, Rene","first_name":"Rene","last_name":"Lenobel"},{"full_name":"Friedecká, Jaroslava","first_name":"Jaroslava","last_name":"Friedecká"},{"first_name":"Aleksandra","last_name":"Skirycz","full_name":"Skirycz, Aleksandra"},{"orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml","first_name":"Jiří","full_name":"Friml, Jiří"}],"PlanS_conform":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","ddc":["580"],"publication":"Science Advances","language":[{"iso":"eng"}],"intvolume":"        12","issue":"19","citation":{"apa":"Li, M., Chodasiewicz, M., Muraleedharan, M., Lopez, I. M., Gorka, M., Kerber, O., … Friml, J. (2026). Biogenesis and downstream effects of 3’,5’ and 2’,3’ cAMP isomers in plants. <i>Science Advances</i>. AAAS. <a href=\"https://doi.org/10.1126/sciadv.aea7828\">https://doi.org/10.1126/sciadv.aea7828</a>","mla":"Li, Mingyue, et al. “Biogenesis and Downstream Effects of 3’,5’ and 2’,3’ CAMP Isomers in Plants.” <i>Science Advances</i>, vol. 12, no. 19, aea7828, AAAS, 2026, doi:<a href=\"https://doi.org/10.1126/sciadv.aea7828\">10.1126/sciadv.aea7828</a>.","short":"M. Li, M. Chodasiewicz, M. Muraleedharan, I.M. Lopez, M. Gorka, O. Kerber, S.S. Alotaibi, A.D.L. Nelson, R. Lenobel, J. Friedecká, A. Skirycz, J. Friml, Science Advances 12 (2026).","chicago":"Li, Mingyue, Monika Chodasiewicz, Malavika Muraleedharan, Israel M. Lopez, Michal Gorka, Olga Kerber, Saqer S. Alotaibi, et al. “Biogenesis and Downstream Effects of 3’,5’ and 2’,3’ CAMP Isomers in Plants.” <i>Science Advances</i>. AAAS, 2026. <a href=\"https://doi.org/10.1126/sciadv.aea7828\">https://doi.org/10.1126/sciadv.aea7828</a>.","ieee":"M. Li <i>et al.</i>, “Biogenesis and downstream effects of 3’,5’ and 2’,3’ cAMP isomers in plants,” <i>Science Advances</i>, vol. 12, no. 19. AAAS, 2026.","ista":"Li M, Chodasiewicz M, Muraleedharan M, Lopez IM, Gorka M, Kerber O, Alotaibi SS, Nelson ADL, Lenobel R, Friedecká J, Skirycz A, Friml J. 2026. Biogenesis and downstream effects of 3’,5’ and 2’,3’ cAMP isomers in plants. Science Advances. 12(19), aea7828.","ama":"Li M, Chodasiewicz M, Muraleedharan M, et al. Biogenesis and downstream effects of 3’,5’ and 2’,3’ cAMP isomers in plants. <i>Science Advances</i>. 2026;12(19). doi:<a href=\"https://doi.org/10.1126/sciadv.aea7828\">10.1126/sciadv.aea7828</a>"},"file":[{"file_id":"21941","file_name":"2026_ScienceAdv_Li2.pdf","creator":"dernst","date_created":"2026-06-02T14:33:55Z","relation":"main_file","checksum":"75b8ef2db078652c750e34e9cd98a808","access_level":"open_access","file_size":2014452,"success":1,"content_type":"application/pdf","date_updated":"2026-06-02T14:33:55Z"}],"publisher":"AAAS","article_processing_charge":"Yes","date_published":"2026-05-08T00:00:00Z","day":"08","file_date_updated":"2026-06-02T14:33:55Z","article_number":"aea7828","external_id":{"pmid":["42102187"]},"type":"journal_article","DOAJ_listed":"1","volume":12,"has_accepted_license":"1","doi":"10.1126/sciadv.aea7828","publication_identifier":{"eissn":["2375-2548"]},"article_type":"original","month":"05","quality_controlled":"1"},{"status":"public","_id":"21962","title":"Mtor/Rptor function globally prevents cortical microcephaly and cell-autonomously promotes postnatal neuron survival in cell type specific manner","oa":1,"date_created":"2026-06-09T08:08:18Z","abstract":[{"lang":"eng","text":"The generation of faithful cell-type diversity and correct projection neuron numbers is essential for cerebral cortex development. Corticogenesis is however susceptible to genetic interference of critical signaling pathways, including mutations in Mtor/Rptor that lead to microcephaly. How the loss of Rptor/mTORC1 function affects cortical developmental programs, at single cell level, is still unknown. Here, we utilized Mosaic Analysis with Double Markers (MADM) technology to probe Rptor gene function upon sparse single cell- or global tissue-wide ablation. We found that tissue-wide effects drive the etiology of cortical microcephaly upon loss of Rptor, rather than deficits in projection neuron genesis. Conversely, Rptor function is cell-autonomously required for postnatal projection neuron survival in a highly cell-type-specific manner. Collectively, our results suggest that the fine balance of precise cell-type-specific cell-autonomous Rptor/mTORC1 function in concert with non-cell-autonomous tissue-wide effects is essential for the development of a properly-sized cerebral cortex with accurate projection neuron diversity."}],"oa_version":"Preprint","date_updated":"2026-06-16T08:45:25Z","year":"2026","project":[{"_id":"264E56E2-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","grant_number":"M02416","name":"Molecular Mechanisms Regulating Gliogenesis in the Neocortex"},{"grant_number":"618444","name":"Molecular Mechanisms of Cerebral Cortex Development","call_identifier":"FP7","_id":"25D61E48-B435-11E9-9278-68D0E5697425"},{"call_identifier":"H2020","_id":"260018B0-B435-11E9-9278-68D0E5697425","name":"Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development","grant_number":"725780"}],"OA_type":"green","publication_status":"submitted","type":"preprint","has_accepted_license":"1","doi":"10.64898/2026.05.01.722172","month":"05","department":[{"_id":"SiHi"}],"acknowledgement":"We thank A. Heger (IST Austria Preclinical Facility), A. Sommer (VBCF GmbH, NGS Unit), and A.\r\nNicolas (IST Austria Lab Support Facility / Mass Spectrometry Facility) for technical support; K. Ferencak,\r\nI. Aykara, P. Hirschfeld, E. Fisher, S. Laukoter, L. Andersen for initial experiments and/or assistance; and\r\nall members of the Hippenmeyer lab for discussion. This research was supported by the Scientific Service\r\nUnits (SSU) of IST Austria through resources provided by the Imaging and Optics- (IOF), Lab Support-\r\n(LSF) and Preclinical Facilities (PCF). R.B. received support from FWF Meitner-Programm (M 2416). This\r\nwork was also supported by IST Austria institutional funds; the People Programme (Marie Curie Actions)\r\nof the European Union’s Seventh Framework Programme (FP7/2007-2013) under REA grant agreement\r\nNo 618444 to S.H., and the European Research Council (ERC) under the European Union’s Horizon 2020\r\nresearch and innovation programme (grant agreement No 725780 LinPro) to S.H.","OA_place":"repository","acknowledged_ssus":[{"_id":"PreCl"},{"_id":"LifeSc"},{"_id":"MassSpec"},{"_id":"Bio"}],"ec_funded":1,"author":[{"id":"68cb85a0-39f7-11eb-9559-9aaab4f6a247","orcid":"0000-0002-5615-5277","full_name":"Villalba Requena, Ana","last_name":"Villalba Requena","first_name":"Ana"},{"first_name":"Robert J","last_name":"Beattie","full_name":"Beattie, Robert J","orcid":"0000-0002-8483-8753","id":"2E26DF60-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Pauler, Florian","last_name":"Pauler","first_name":"Florian","id":"48EA0138-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-7462-0048"},{"id":"36BCB99C-F248-11E8-B48F-1D18A9856A87","last_name":"Streicher","first_name":"Carmen","full_name":"Streicher, Carmen"},{"full_name":"Miranda, Osvaldo","last_name":"Miranda","first_name":"Osvaldo","id":"862A3C56-A8BF-11E9-B4FA-D9E3E5697425","orcid":"0000-0001-6618-6889"},{"first_name":"Thomas","last_name":"Krausgruber","full_name":"Krausgruber, Thomas"},{"first_name":"Martin","last_name":"Senekowitsch","full_name":"Senekowitsch, Martin"},{"last_name":"Farlik","first_name":"Matthias","full_name":"Farlik, Matthias"},{"full_name":"Bock, Christoph","first_name":"Christoph","last_name":"Bock"},{"full_name":"Rülicke, Thomas","first_name":"Thomas","last_name":"Rülicke"},{"full_name":"Hippenmeyer, Simon","first_name":"Simon","last_name":"Hippenmeyer","id":"37B36620-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2279-1061"}],"tmp":{"name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","short":"CC BY-NC (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","image":"/images/cc_by_nc.png"},"ddc":["570"],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"bioRxiv","language":[{"iso":"eng"}],"citation":{"short":"A. Villalba Requena, R.J. Beattie, F. Pauler, C. Streicher, O. Miranda, T. Krausgruber, M. Senekowitsch, M. Farlik, C. Bock, T. Rülicke, S. Hippenmeyer, BioRxiv (n.d.).","ama":"Villalba Requena A, Beattie RJ, Pauler F, et al. Mtor/Rptor function globally prevents cortical microcephaly and cell-autonomously promotes postnatal neuron survival in cell type specific manner. <i>bioRxiv</i>. doi:<a href=\"https://doi.org/10.64898/2026.05.01.722172\">10.64898/2026.05.01.722172</a>","chicago":"Villalba Requena, Ana, Robert J Beattie, Florian Pauler, Carmen Streicher, Osvaldo Miranda, Thomas Krausgruber, Martin Senekowitsch, et al. “Mtor/Rptor Function Globally Prevents Cortical Microcephaly and Cell-Autonomously Promotes Postnatal Neuron Survival in Cell Type Specific Manner.” <i>BioRxiv</i>, n.d. <a href=\"https://doi.org/10.64898/2026.05.01.722172\">https://doi.org/10.64898/2026.05.01.722172</a>.","ista":"Villalba Requena A, Beattie RJ, Pauler F, Streicher C, Miranda O, Krausgruber T, Senekowitsch M, Farlik M, Bock C, Rülicke T, Hippenmeyer S. Mtor/Rptor function globally prevents cortical microcephaly and cell-autonomously promotes postnatal neuron survival in cell type specific manner. bioRxiv, <a href=\"https://doi.org/10.64898/2026.05.01.722172\">10.64898/2026.05.01.722172</a>.","ieee":"A. Villalba Requena <i>et al.</i>, “Mtor/Rptor function globally prevents cortical microcephaly and cell-autonomously promotes postnatal neuron survival in cell type specific manner,” <i>bioRxiv</i>. .","mla":"Villalba Requena, Ana, et al. “Mtor/Rptor Function Globally Prevents Cortical Microcephaly and Cell-Autonomously Promotes Postnatal Neuron Survival in Cell Type Specific Manner.” <i>BioRxiv</i>, doi:<a href=\"https://doi.org/10.64898/2026.05.01.722172\">10.64898/2026.05.01.722172</a>.","apa":"Villalba Requena, A., Beattie, R. J., Pauler, F., Streicher, C., Miranda, O., Krausgruber, T., … Hippenmeyer, S. (n.d.). Mtor/Rptor function globally prevents cortical microcephaly and cell-autonomously promotes postnatal neuron survival in cell type specific manner. <i>bioRxiv</i>. <a href=\"https://doi.org/10.64898/2026.05.01.722172\">https://doi.org/10.64898/2026.05.01.722172</a>"},"article_processing_charge":"No","day":"05","date_published":"2026-05-05T00:00:00Z","main_file_link":[{"url":"https://doi.org/10.64898/2026.05.01.722172","open_access":"1"}]},{"OA_type":"hybrid","publication_status":"published","page":"5752-5762","year":"2026","project":[{"name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery","_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A"}],"date_updated":"2026-08-19T05:53:33Z","scopus_import":"1","oa_version":"Published Version","date_created":"2026-08-18T11:34:03Z","oa":1,"abstract":[{"text":"Silver selenide (Ag2Se) is a promising near-room-temperature thermoelectric material, but its narrow stoichiometric window and β–α phase transition complicate reproducible microstructure control. Here, we present a mismatch-assisted microstructure engineering strategy in which Ag2Se particles are treated with polyanionic ZnSe complexes and consolidated through the β–α transition to introduce ZnSe nanoprecipitates, Ag2Se/ZnSe interfaces, and local strain fields. The crystallographic mismatch between ZnSe and Ag2Se, together with the Zn2+/Ag+ size difference, amplifies phase-transition-induced deformation and promotes high-density dislocations with periodic strain modulations. This defect architecture suppresses grain coarsening, removes excess Ag, limits Ag-interstitial formation, and reduces lattice thermal conductivity through lattice softening and multiscale phonon scattering. Ag2Se–4%ZnSe nanocomposites achieve a peak zTmax of 1.13 at 369 K and a zTavg of 1.08 from 300 to 380 K, demonstrating mismatch-driven defect engineering through the β–α phase transition as a route for optimizing Ag2Se-based thermoelectrics.","lang":"eng"}],"status":"public","_id":"22734","title":"Exploiting mismatch strain and the β–α phase transition for microstructural engineering in thermoelectric Ag2Se","das_tickbox":"0","corr_author":"1","article_processing_charge":"Yes (via OA deal)","day":"14","date_published":"2026-08-14T00:00:00Z","file_date_updated":"2026-08-19T05:52:41Z","intvolume":"        11","supplementarymaterial":"yes","issue":"8","citation":{"ieee":"Y. Liu <i>et al.</i>, “Exploiting mismatch strain and the β–α phase transition for microstructural engineering in thermoelectric Ag2Se,” <i>ACS Energy Letters</i>, vol. 11, no. 8. American Chemical Society, pp. 5752–5762, 2026.","ista":"Liu Y, Kleinhanns T, Spadaro MC, Genç A, Horta S, Jakhar N, Costanzo T, Dutkiewicz E, Arbiol J, Hong M, Ibáñez M. 2026. Exploiting mismatch strain and the β–α phase transition for microstructural engineering in thermoelectric Ag2Se. ACS Energy Letters. 11(8), 5752–5762.","chicago":"Liu, Yu, Tobias Kleinhanns, Maria Chiara Spadaro, Aziz Genç, Sharona Horta, Navita Jakhar, Tommaso Costanzo, et al. “Exploiting Mismatch Strain and the β–α Phase Transition for Microstructural Engineering in Thermoelectric Ag2Se.” <i>ACS Energy Letters</i>. American Chemical Society, 2026. <a href=\"https://doi.org/10.1021/acsenergylett.6c01499\">https://doi.org/10.1021/acsenergylett.6c01499</a>.","ama":"Liu Y, Kleinhanns T, Spadaro MC, et al. Exploiting mismatch strain and the β–α phase transition for microstructural engineering in thermoelectric Ag2Se. <i>ACS Energy Letters</i>. 2026;11(8):5752-5762. doi:<a href=\"https://doi.org/10.1021/acsenergylett.6c01499\">10.1021/acsenergylett.6c01499</a>","short":"Y. Liu, T. Kleinhanns, M.C. Spadaro, A. Genç, S. Horta, N. Jakhar, T. Costanzo, E. Dutkiewicz, J. Arbiol, M. Hong, M. Ibáñez, ACS Energy Letters 11 (2026) 5752–5762.","apa":"Liu, Y., Kleinhanns, T., Spadaro, M. C., Genç, A., Horta, S., Jakhar, N., … Ibáñez, M. (2026). Exploiting mismatch strain and the β–α phase transition for microstructural engineering in thermoelectric Ag2Se. <i>ACS Energy Letters</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsenergylett.6c01499\">https://doi.org/10.1021/acsenergylett.6c01499</a>","mla":"Liu, Yu, et al. “Exploiting Mismatch Strain and the β–α Phase Transition for Microstructural Engineering in Thermoelectric Ag2Se.” <i>ACS Energy Letters</i>, vol. 11, no. 8, American Chemical Society, 2026, pp. 5752–62, doi:<a href=\"https://doi.org/10.1021/acsenergylett.6c01499\">10.1021/acsenergylett.6c01499</a>."},"file":[{"date_created":"2026-08-19T05:52:41Z","file_name":"2026_ACSEnergyLetters_Liu.pdf","creator":"dernst","file_id":"22736","file_size":6806815,"access_level":"open_access","date_updated":"2026-08-19T05:52:41Z","success":1,"content_type":"application/pdf","relation":"main_file","checksum":"4d75c5a79d112c845c9eecba8838db38"}],"publisher":"American Chemical Society","researchdata_availability":"no","PlanS_conform":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"ddc":["540"],"language":[{"iso":"eng"}],"publication":"ACS Energy Letters","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"MassSpec"},{"_id":"MaIb"},{"_id":"GradSch"},{"_id":"EM-Fac"}],"acknowledgement":"Open access funding provided by Institute of Science and Technology Austria. M.I. acknowledges financial support from ISTA and the Werner Siemens Foundation. The Scientific Service Units (SSU) of ISTA supported this work through resources provided by the Electron Microscopy Facility (EMF), the Lab Support Facility (LSF), the Nanofabrication Facility (NNF), and the Mass Spectrometry Facility. Y.L. acknowledges funding from the National Natural Science Foundation of China (NSFC) (grant no. 22209034) and the Fundamental Research Funds for the Central Universities (JZ2024HGTB0239). M.H. acknowledges funding from Australian Research Council (FT230100316), and the high-performance computing resources provided by National Computational Infrastructure (it39) and Pawsey Supercomputing Centre (pawsey1075). ICN2 acknowledges funding from Generalitat de Catalunya 2021SGR00457. The authors thank support from the project AMaDE (PID2023-149158OB-C43), funded by MCIN/AEI/10.13039/501100011033/ and by the “ERDF Away of making Europe”, by the “European Union”. ICN2 is supported by the Severo Ochoa program from Spanish MCIN/AEI (grant no.: CEX2021-001214-S) and is funded by the CERCA Programme/Generalitat de Catalunya. Authors acknowledge the use of instrumentation as well as the technical advice provided by the Joint Electron Microscopy Center at ALBA (JEMCA). ICN2 acknowledges funding from Grant IU16-014206 (METCAM-FIB) funded by the European Union through the European Regional Development Fund (ERDF), with the support of the Ministry of Research and Universities, Generalitat de Catalunya. ICN2 is founding member of e-DREAM. (91)","acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"LifeSc"},{"_id":"NanoFab"},{"_id":"MassSpec"}],"OA_place":"publisher","author":[{"first_name":"Yu","last_name":"Liu","full_name":"Liu, Yu","orcid":"0000-0001-7313-6740","id":"2A70014E-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Tobias","last_name":"Kleinhanns","full_name":"Kleinhanns, Tobias","orcid":"0000-0003-1537-7436","id":"8BD9DE16-AB3C-11E9-9C8C-2A03E6697425"},{"full_name":"Spadaro, Maria Chiara","last_name":"Spadaro","first_name":"Maria Chiara"},{"full_name":"Genç, Aziz","first_name":"Aziz","last_name":"Genç"},{"id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc","full_name":"Horta, Sharona","last_name":"Horta","first_name":"Sharona"},{"orcid":"0000-0001-7408-8197","id":"6ebe278d-ba0b-11ee-8184-f34cdc671de4","last_name":"Navita","first_name":"Navita","full_name":"Navita, Navita"},{"first_name":"Tommaso","last_name":"Costanzo","full_name":"Costanzo, Tommaso","orcid":"0000-0001-9732-3815","id":"D93824F4-D9BA-11E9-BB12-F207E6697425"},{"id":"0601cc46-c082-11ec-9b07-bb29641d1de9","full_name":"Dutkiewicz, Ewelina","first_name":"Ewelina","last_name":"Dutkiewicz"},{"full_name":"Arbiol, Jordi","first_name":"Jordi","last_name":"Arbiol"},{"full_name":"Hong, Min","first_name":"Min","last_name":"Hong"},{"first_name":"Maria","last_name":"Ibáñez","full_name":"Ibáñez, Maria","orcid":"0000-0001-5013-2843","id":"43C61214-F248-11E8-B48F-1D18A9856A87"}],"article_type":"letter_note","month":"08","quality_controlled":"1","publication_identifier":{"eissn":["2380-8195"]},"has_accepted_license":"1","volume":11,"doi":"10.1021/acsenergylett.6c01499","type":"journal_article"},{"intvolume":"        16","file":[{"checksum":"06244623bb7611c636652ecbc4787889","relation":"main_file","content_type":"application/pdf","date_updated":"2025-12-15T13:30:33Z","success":1,"file_size":805323,"access_level":"open_access","file_id":"20826","creator":"dernst","file_name":"2025_NatureComm_Dawson.pdf","date_created":"2025-12-15T13:30:33Z"}],"publisher":"Springer Nature","citation":{"short":"E. Dawson, M. Hönigsberger, N. Kampleitner, A.V. Grasse, L. Lindorfer, J. Robb, F. Beikzadeh, F. Strahodinsky, H. Leitner, H. Rajendran, T. Schmitt, S. Cremer, Nature Communications 16 (2025).","ama":"Dawson E, Hönigsberger M, Kampleitner N, et al. Altruistic disease signalling in ant colonies. <i>Nature Communications</i>. 2025;16. doi:<a href=\"https://doi.org/10.1038/s41467-025-66175-z\">10.1038/s41467-025-66175-z</a>","chicago":"Dawson, Erika, Michaela Hönigsberger, Niklas Kampleitner, Anna V Grasse, Lukas Lindorfer, Jennifer Robb, Farnaz Beikzadeh, et al. “Altruistic Disease Signalling in Ant Colonies.” <i>Nature Communications</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41467-025-66175-z\">https://doi.org/10.1038/s41467-025-66175-z</a>.","ieee":"E. Dawson <i>et al.</i>, “Altruistic disease signalling in ant colonies,” <i>Nature Communications</i>, vol. 16. Springer Nature, 2025.","ista":"Dawson E, Hönigsberger M, Kampleitner N, Grasse AV, Lindorfer L, Robb J, Beikzadeh F, Strahodinsky F, Leitner H, Rajendran H, Schmitt T, Cremer S. 2025. Altruistic disease signalling in ant colonies. Nature Communications. 16, 10511.","mla":"Dawson, Erika, et al. “Altruistic Disease Signalling in Ant Colonies.” <i>Nature Communications</i>, vol. 16, 10511, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1038/s41467-025-66175-z\">10.1038/s41467-025-66175-z</a>.","apa":"Dawson, E., Hönigsberger, M., Kampleitner, N., Grasse, A. V., Lindorfer, L., Robb, J., … Cremer, S. (2025). Altruistic disease signalling in ant colonies. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-025-66175-z\">https://doi.org/10.1038/s41467-025-66175-z</a>"},"date_published":"2025-12-01T00:00:00Z","day":"01","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/2024.02.27.582277"}],"article_processing_charge":"Yes","article_number":"10511","file_date_updated":"2025-12-15T13:30:33Z","acknowledgement":"We thank Joergen Eilenberg and Nicolai V. Meyling for the fungal strain, and the ISTA Social Immunity team, Jonghyun Park and Yuko Ulrich for ant collection. We also thank the Social Immunity team, in particular David Moreno Martínez, Tanvi Madaan, Wilfrid Jean Louis and Jessica Kirchner, for experimental and molecular support, as well as Friedrich Fochler for technical support with the chemical analysis, and the ISTA Lab Support Facility, including the mass spectrometry unit, for general and chemical laboratory support. We further thank Marco Ribezzi for advice on 13C calculations and Ernst Pittenauer for discussion of the chemical data, Chris Pull and Michael Sixt for project discussion, and the Social Immunity team for comments on the manuscript. The study was funded by the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation Programme (No. 771402; EPIDEMICSonCHIP) to SC.","related_material":{"link":[{"relation":"press_release","url":"https://ista.ac.at/en/news/ants-signal-deadly-infection/","description":"News on ISTA website"}],"record":[{"id":"20471","relation":"research_data","status":"public"}]},"department":[{"_id":"SyCr"},{"_id":"LifeSc"}],"ec_funded":1,"author":[{"id":"31B4E2D0-F248-11E8-B48F-1D18A9856A87","first_name":"Erika","last_name":"Dawson","full_name":"Dawson, Erika"},{"full_name":"Hönigsberger, Michaela","first_name":"Michaela","last_name":"Hönigsberger","id":"953894f3-25bd-11ec-8556-f70a9d38ef60"},{"id":"2AC57FAC-F248-11E8-B48F-1D18A9856A87","last_name":"Kampleitner","first_name":"Niklas","full_name":"Kampleitner, Niklas"},{"first_name":"Anna V","last_name":"Grasse","full_name":"Grasse, Anna V","id":"406F989C-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Lukas","last_name":"Lindorfer","full_name":"Lindorfer, Lukas","id":"85f0e6d3-06b3-11ec-8982-8c5049fa4455"},{"id":"7bc2734a-e2c6-11ea-9824-a2ed5f0662a8","first_name":"Jennifer","last_name":"Robb","full_name":"Robb, Jennifer"},{"last_name":"Beikzadeh Abbasi","first_name":"Farnaz","full_name":"Beikzadeh Abbasi, Farnaz","id":"0344bfb9-3feb-11ee-87e9-c27edc800bcd"},{"id":"979E35EE-C996-11E9-8C7C-CF13E6697425","last_name":"Strahodinsky","first_name":"Florian","full_name":"Strahodinsky, Florian"},{"full_name":"Leitner, Hanna","first_name":"Hanna","last_name":"Leitner","id":"8fc5c6f6-5903-11ec-abad-c83f046253e7"},{"full_name":"Rajendran, Harikrishnan","first_name":"Harikrishnan","last_name":"Rajendran","id":"876b6b34-8ff4-11ec-97c9-8d95a7aae416"},{"full_name":"Schmitt, Thomas","last_name":"Schmitt","first_name":"Thomas"},{"orcid":"0000-0002-2193-3868","id":"2F64EC8C-F248-11E8-B48F-1D18A9856A87","first_name":"Sylvia","last_name":"Cremer","full_name":"Cremer, Sylvia"}],"acknowledged_ssus":[{"_id":"LifeSc"},{"_id":"MassSpec"}],"OA_place":"publisher","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"PlanS_conform":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Nature Communications","ddc":["570"],"language":[{"iso":"eng"}],"publication_identifier":{"eissn":["2041-1723"]},"article_type":"original","quality_controlled":"1","month":"12","type":"journal_article","external_id":{"pmid":["41330896"]},"DOAJ_listed":"1","doi":"10.1038/s41467-025-66175-z","volume":16,"has_accepted_license":"1","year":"2025","project":[{"name":"Epidemics in ant societies on a chip","grant_number":"771402","_id":"2649B4DE-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"},{"_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854","name":"IST Austria Open Access Fund"}],"pmid":1,"APC_amount":"7068 EUR","publication_status":"published","OA_type":"gold","scopus_import":"1","oa_version":"Published Version","date_updated":"2026-06-10T08:50:53Z","_id":"18892","status":"public","title":"Altruistic disease signalling in ant colonies","abstract":[{"lang":"eng","text":"Sick individuals often conceal their disease status to group members, thereby preventing social exclusion or aggression. Here we show by behavioural, chemical, immunological and infection load analyses that sick ant pupae instead actively emit a chemical signal that in itself is sufficient to trigger their own destruction by colony members. In our experiments, this altruistic disease-signalling was performed only by worker but not queen pupae. The lack of signalling by queen pupae did not constitute cheating behaviour, but reflected their superior immune capabilities. Worker pupae suffered from extensive pathogen replication whereas queen pupae were able to restrain their infection. Our data suggest the evolution of a finely-tuned signalling system in which it is not the induction of an individual’s immune response, but rather its failure to overcome the infection, that triggers pupal signalling for sacrifice. This demonstrates a balanced interplay between individual and social immunity that efficiently achieves whole-colony health."}],"date_created":"2025-01-27T11:28:05Z","oa":1,"corr_author":"1"},{"publication_identifier":{"issn":["0002-7863"],"eissn":["1520-5126"]},"month":"08","quality_controlled":"1","article_type":"original","external_id":{"isi":["001558320100001"]},"type":"journal_article","has_accepted_license":"1","volume":147,"doi":"10.1021/jacs.5c11435","citation":{"ama":"Liu Y, Kleinhanns T, Horta S, et al. Liquid-solid interface reactions drive enhanced thermoelectric performance in Ag2Se. <i>Journal of the American Chemical Society</i>. 2025;147(35):32199-32208. doi:<a href=\"https://doi.org/10.1021/jacs.5c11435\">10.1021/jacs.5c11435</a>","ista":"Liu Y, Kleinhanns T, Horta S, Dutkiewicz E, Lu S, Spadaro MC, Genç A, Chen L, Lim KH, Hong M, Arbiol J, Ibáñez M. 2025. Liquid-solid interface reactions drive enhanced thermoelectric performance in Ag2Se. Journal of the American Chemical Society. 147(35), 32199–32208.","ieee":"Y. Liu <i>et al.</i>, “Liquid-solid interface reactions drive enhanced thermoelectric performance in Ag2Se,” <i>Journal of the American Chemical Society</i>, vol. 147, no. 35. American Chemical Society, pp. 32199–32208, 2025.","chicago":"Liu, Yu, Tobias Kleinhanns, Sharona Horta, Ewelina Dutkiewicz, Shaoqing Lu, Maria Chiara Spadaro, Aziz Genç, et al. “Liquid-Solid Interface Reactions Drive Enhanced Thermoelectric Performance in Ag2Se.” <i>Journal of the American Chemical Society</i>. American Chemical Society, 2025. <a href=\"https://doi.org/10.1021/jacs.5c11435\">https://doi.org/10.1021/jacs.5c11435</a>.","short":"Y. Liu, T. Kleinhanns, S. Horta, E. Dutkiewicz, S. Lu, M.C. Spadaro, A. Genç, L. Chen, K.H. Lim, M. Hong, J. Arbiol, M. Ibáñez, Journal of the American Chemical Society 147 (2025) 32199–32208.","mla":"Liu, Yu, et al. “Liquid-Solid Interface Reactions Drive Enhanced Thermoelectric Performance in Ag2Se.” <i>Journal of the American Chemical Society</i>, vol. 147, no. 35, American Chemical Society, 2025, pp. 32199–208, doi:<a href=\"https://doi.org/10.1021/jacs.5c11435\">10.1021/jacs.5c11435</a>.","apa":"Liu, Y., Kleinhanns, T., Horta, S., Dutkiewicz, E., Lu, S., Spadaro, M. C., … Ibáñez, M. (2025). Liquid-solid interface reactions drive enhanced thermoelectric performance in Ag2Se. <i>Journal of the American Chemical Society</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/jacs.5c11435\">https://doi.org/10.1021/jacs.5c11435</a>"},"file":[{"date_created":"2025-09-10T06:55:17Z","file_id":"20334","creator":"dernst","file_name":"2025_JACS_Liu.pdf","success":1,"date_updated":"2025-09-10T06:55:17Z","content_type":"application/pdf","file_size":9997327,"access_level":"open_access","checksum":"52892fa91adadd39a1c42da9e01139a5","relation":"main_file"}],"publisher":"American Chemical Society","intvolume":"       147","issue":"35","file_date_updated":"2025-09-10T06:55:17Z","article_processing_charge":"Yes (via OA deal)","day":"22","date_published":"2025-08-22T00:00:00Z","OA_place":"publisher","acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"LifeSc"},{"_id":"NanoFab"},{"_id":"MassSpec"}],"author":[{"full_name":"Liu, Yu","last_name":"Liu","first_name":"Yu","id":"2A70014E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-7313-6740"},{"orcid":"0000-0003-1537-7436","id":"8BD9DE16-AB3C-11E9-9C8C-2A03E6697425","last_name":"Kleinhanns","first_name":"Tobias","full_name":"Kleinhanns, Tobias"},{"full_name":"Horta, Sharona","last_name":"Horta","first_name":"Sharona","id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc"},{"id":"0601cc46-c082-11ec-9b07-bb29641d1de9","last_name":"Dutkiewicz","first_name":"Ewelina","full_name":"Dutkiewicz, Ewelina"},{"full_name":"Lu, Shaoqing","first_name":"Shaoqing","last_name":"Lu"},{"full_name":"Spadaro, Maria Chiara","last_name":"Spadaro","first_name":"Maria Chiara"},{"full_name":"Genç, Aziz","first_name":"Aziz","last_name":"Genç"},{"first_name":"Lei","last_name":"Chen","full_name":"Chen, Lei"},{"last_name":"Lim","first_name":"Khak Ho","full_name":"Lim, Khak Ho"},{"full_name":"Hong, Min","first_name":"Min","last_name":"Hong"},{"full_name":"Arbiol, Jordi","last_name":"Arbiol","first_name":"Jordi"},{"orcid":"0000-0001-5013-2843","id":"43C61214-F248-11E8-B48F-1D18A9856A87","last_name":"Ibáñez","first_name":"Maria","full_name":"Ibáñez, Maria"}],"department":[{"_id":"MaIb"},{"_id":"MassSpec"}],"related_material":{"record":[{"id":"22017","status":"public","relation":"dissertation_contains"}]},"acknowledgement":"M.I. acknowledges financial support from ISTA and the Werner Siemens Foundation. The Scientific Service Units (SSU) of ISTA supported this work through resources provided by the Electron Microscopy Facility (EMF), the Lab Support Facility (LSF) and the Nanofabrication Facility (NNF) and the LSF Mass Spectrometry Service. The members of the Ibáñez research group are acknowledged, especially Christine Fiedler for scientific illustration and Ihor Cherniukh for valuable discussions. Y.L. acknowledges funding from the National Natural Science Foundation of China (NSFC) (Grants No. 22209034), the Innovation and Entrepreneurship Project of Overseas Returnees in Anhui Province (Grant No. 2022LCX002) and the Fundamental Research Funds for the Central Universities (JZ2024HGTB0239). K.H.L. acknowledges financial support from the National Natural Science Foundation of China (NSFC) (Grant No. 22208293). ICN2 acknowledges funding from Generalitat de Catalunya 2021SGR00457. Authors acknowledge the Advanced Materials programme by the Spanish Government with funding from European Union NextGenerationEU (PRTR-C17.I1) and by Generalitat de Catalunya (Project In-CAEM). The authors thank support from the project AMaDE (PID2023-149158OB-C43), funded by MCIN/AEI/10.13039/501100011033/and by “ERDF Away of making Europe”, by the “European Union”. ICN2 is supported by the Severo Ochoa program from Spanish MCIN/AEI (Grant No.: CEX2021-001214-S) and is funded by the CERCA Programme/Generalitat de Catalunya. ICN2 is founding member of e-DREAM. (68) M.H. acknowledges the funding from the Australian Research Council (FT230100316 and IH200100035). M.H. acknowledges the computational support from the National Computational Infrastructure (NCI) and Pawsey Supercomputing Centre, Australia.","ddc":["540"],"publication":"Journal of the American Chemical Society","language":[{"iso":"eng"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","PlanS_conform":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"title":"Liquid-solid interface reactions drive enhanced thermoelectric performance in Ag2Se","_id":"20326","status":"public","oa":1,"date_created":"2025-09-10T05:44:03Z","abstract":[{"lang":"eng","text":"Ag2Se is a promising n-type thermoelectric material, but its performance is limited by excessive carrier concentration, compositional inhomogeneity, and phase instability, challenges rooted in a narrow homogeneity range and uncontrolled Ag+ diffusion in the superionic phase. Here, we address these issues by exploiting liquid–solid interface reactions using CdSe complexes that remove surface excess Ag to yield stoichiometric Ag2Se and generate CdSe nanodomains that inhibit Ag+ diffusion and constrain grain growth. The resulting Ag2Se-CdSe nanocomposites exhibit a reproducible, stable figure of merit (zT) of 1.04 between 300 and 390 K. Beyond demonstrating high performance, we elucidate the interfacial chemical reactions that give rise to the observed microstructure and transport properties, providing a foundation for rationally engineering interfacial chemistry to tailor transport properties across diverse thermoelectric material systems."}],"isi":1,"corr_author":"1","project":[{"_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A","name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery"}],"year":"2025","OA_type":"hybrid","page":"32199-32208","publication_status":"published","oa_version":"Published Version","scopus_import":"1","date_updated":"2026-07-28T09:55:14Z"},{"issue":"36","intvolume":"        25","publisher":"American Chemical Society","file":[{"file_id":"20910","file_name":"2025_NanoLetters_York.pdf","creator":"dernst","date_created":"2025-12-30T09:39:44Z","checksum":"bac881601e1f33c3cf8f51d50b958e68","relation":"main_file","date_updated":"2025-12-30T09:39:44Z","content_type":"application/pdf","success":1,"access_level":"open_access","file_size":3144989}],"citation":{"apa":"York, E., Stone, I., Shi, W., Roy, X., &#38; Venkataraman, L. (2025). Tuning conductance in BODIPY-based single-molecule junctions. <i>Nano Letters</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acs.nanolett.5c03764\">https://doi.org/10.1021/acs.nanolett.5c03764</a>","mla":"York, Emma, et al. “Tuning Conductance in BODIPY-Based Single-Molecule Junctions.” <i>Nano Letters</i>, vol. 25, no. 36, American Chemical Society, 2025, pp. 13697–702, doi:<a href=\"https://doi.org/10.1021/acs.nanolett.5c03764\">10.1021/acs.nanolett.5c03764</a>.","short":"E. York, I. Stone, W. Shi, X. Roy, L. Venkataraman, Nano Letters 25 (2025) 13697–13702.","ieee":"E. York, I. Stone, W. Shi, X. Roy, and L. Venkataraman, “Tuning conductance in BODIPY-based single-molecule junctions,” <i>Nano Letters</i>, vol. 25, no. 36. American Chemical Society, pp. 13697–13702, 2025.","chicago":"York, Emma, Ilana Stone, Wanzhuo Shi, Xavier Roy, and Latha Venkataraman. “Tuning Conductance in BODIPY-Based Single-Molecule Junctions.” <i>Nano Letters</i>. American Chemical Society, 2025. <a href=\"https://doi.org/10.1021/acs.nanolett.5c03764\">https://doi.org/10.1021/acs.nanolett.5c03764</a>.","ista":"York E, Stone I, Shi W, Roy X, Venkataraman L. 2025. Tuning conductance in BODIPY-based single-molecule junctions. Nano Letters. 25(36), 13697–13702.","ama":"York E, Stone I, Shi W, Roy X, Venkataraman L. Tuning conductance in BODIPY-based single-molecule junctions. <i>Nano Letters</i>. 2025;25(36):13697-13702. doi:<a href=\"https://doi.org/10.1021/acs.nanolett.5c03764\">10.1021/acs.nanolett.5c03764</a>"},"day":"25","date_published":"2025-08-25T00:00:00Z","article_processing_charge":"Yes (via OA deal)","file_date_updated":"2025-12-30T09:39:44Z","acknowledgement":"We thank the National Science Foundation (No. NSF-DMR 2241180) for supporting this research. Synthetic work at Columbia was funded in part by the Air Force Office of Scientific Research (AFOSR), under Grant No. FA9550-22-1-0389. The cryoprobe on the 500 MHz NMR instrument used in this research at Columbia was purchased through the NIH Award No. S10OD026749. This work was supported in part by the Institute of Science and Technology Austria. HRMS sample preparation, analysis, and data evaluation were performed by Aikaterina Paraskevopoulou, Mass Spec Service, LSF, ISTA.","department":[{"_id":"LaVe"}],"author":[{"last_name":"York","first_name":"Emma","full_name":"York, Emma","id":"08dde91e-8e0a-11f0-9d7d-9e8d80864f16"},{"first_name":"Ilana","last_name":"Stone","full_name":"Stone, Ilana"},{"id":"a3010425-87c8-11f0-8106-bec32bea74da","full_name":"Shi, Wanzhuo","last_name":"Shi","first_name":"Wanzhuo"},{"full_name":"Roy, Xavier","last_name":"Roy","first_name":"Xavier"},{"last_name":"Venkataraman","first_name":"Latha","full_name":"Venkataraman, Latha","orcid":"0000-0002-6957-6089","id":"9ebb78a5-cc0d-11ee-8322-fae086a32caf"}],"OA_place":"publisher","acknowledged_ssus":[{"_id":"LifeSc"},{"_id":"MassSpec"}],"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"PlanS_conform":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","ddc":["540"],"publication":"Nano Letters","language":[{"iso":"eng"}],"publication_identifier":{"eissn":["1530-6992"],"issn":["1530-6984"]},"article_type":"letter_note","quality_controlled":"1","month":"08","type":"journal_article","external_id":{"pmid":["40855728"],"isi":["001557017200001"]},"doi":"10.1021/acs.nanolett.5c03764","volume":25,"has_accepted_license":"1","year":"2025","pmid":1,"page":"13697-13702","publication_status":"published","OA_type":"hybrid","scopus_import":"1","oa_version":"Published Version","date_updated":"2026-07-28T09:53:54Z","status":"public","_id":"20331","title":"Tuning conductance in BODIPY-based single-molecule junctions","abstract":[{"lang":"eng","text":"Here, we present a foundational investigation of charge transport through three BODIPY-based molecules using the scanning tunneling microscope–break junction (STM-BJ) technique. We demonstrate that molecular conductance through the BODIPY core can be measured by introducing aurophilic linkers at the 2,6-positions. By varying these linkers, we systematically modulate the frontier molecular orbital energies and fine-tune transport behavior. Our experimental results are supported by DFT-based calculations, which feature a new computationally efficient correction to standard PBE-level transmission predictions. Together, these findings establish the viability of BODIPY-based systems for molecular junction applications and lay the groundwork for future studies of their single-molecule optoelectronic properties."}],"date_created":"2025-09-10T05:48:29Z","oa":1,"das_tickbox":"1","corr_author":"1","isi":1}]