Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion
S. Stahnke, H. Döring, C. Kusch, D.J.J. de Gorter, S. Dütting, A. Guledani, I. Pleines, M. Schnoor, M.K. Sixt, R. Geffers, M. Rohde, M. Müsken, F. Kage, A. Steffen, J. Faix, B. Nieswandt, K. Rottner, T.E.B. Stradal, Current Biology 31 (2021) 2051–2064.e8.
LibreCat: https://research-explorer.ista.ac.at/record/10834
DOI: 10.1016/j.cub.2021.02.043
WoS: 000654652200002
PMID: 33711252

Dendritic cell actin dynamics control contact duration and priming efficiency at the immunological synapse
A.F. Leithner, L. Altenburger, R. Hauschild, F.P. Assen, K. Rottner, S. TEB, A. Diz-Muñoz, J. Stein, M.K. Sixt, Journal of Cell Biology 220 (2021).
LibreCat: https://research-explorer.ista.ac.at/record/9094
DOI: 10.1083/jcb.202006081
WoS: 000626365700001
PMID: 33533935

Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development
J. Morandell, L.A. Schwarz, B. Basilico, S. Tasciyan, G.A. Dimchev, A. Nicolas, C.M. Sommer, C. Kreuzinger, C. Dotter, L. Knaus, Z. Dobler, E. Cacci, F.K. Schur, J.G. Danzl, G. Novarino, Nature Communications 12 (2021).
LibreCat: https://research-explorer.ista.ac.at/record/9429
DOI: 10.1038/s41467-021-23123-x
WoS: 000658769900010

Pathogenic Escherichia coli hijack the host immune response
K. Tomasek, Pathogenic Escherichia Coli Hijack the Host Immune Response, Institute of Science and Technology Austria, 2021.
LibreCat: https://research-explorer.ista.ac.at/record/10307
DOI: 10.15479/at:ista:10307

Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to C
K. Tomasek, A.F. Leithner, I. Glatzová, M.S. Lukesch, C.C. Guet, M.K. Sixt, BioRxiv (n.d.).
LibreCat: https://research-explorer.ista.ac.at/record/10316
DOI: 10.1101/2021.10.18.464770

Partial loss of actin nucleator actin-related protein 2/3 activity triggers blebbing in primary T lymphocytes
P. Obeidy, L.A. Ju, S.H. Oehlers, N.S. Zulkhernain, Q. Lee, J.L. Galeano Niño, R.Y.Q. Kwan, S. Tikoo, L.L. Cavanagh, P. Mrass, A.J.L. Cook, S.P. Jackson, M. Biro, B. Roediger, M.K. Sixt, W. Weninger, Immunology and Cell Biology 98 (2020) 93–113.
LibreCat: https://research-explorer.ista.ac.at/record/7234
DOI: 10.1111/imcb.12304
WoS: 000503885600001
PMID: 31698518

Modeling adhesion-independent cell migration
G. Jankowiak, D. Peurichard, A. Reversat, C. Schmeiser, M.K. Sixt, Mathematical Models and Methods in Applied Sciences 30 (2020) 513–537.
LibreCat: https://research-explorer.ista.ac.at/record/7623
DOI: 10.1142/S021820252050013X
WoS: 000525349900003
arXiv: 1903.09426

Microtubules control cellular shape and coherence in amoeboid migrating cells
A. Kopf, J. Renkawitz, R. Hauschild, I. Girkontaite, K. Tedford, J. Merrin, O. Thorn-Seshold, D. Trauner, H. Häcker, K.D. Fischer, E. Kiermaier, M.K. Sixt, The Journal of Cell Biology 219 (2020).
LibreCat: https://research-explorer.ista.ac.at/record/7875
DOI: 10.1083/jcb.201907154
WoS: 000538141100020
PMID: 32379884

T cells: Bridge-and-channel commute to the white pulp
M.K. Sixt, T. Lämmermann, Immunity 52 (2020) 721–723.
LibreCat: https://research-explorer.ista.ac.at/record/7876
DOI: 10.1016/j.immuni.2020.04.020
WoS: 000535371100002

Loss of Ena/VASP interferes with lamellipodium architecture, motility and integrin-dependent adhesion
J. Damiano-Guercio, L. Kurzawa, J. Müller, G.A. Dimchev, M. Schaks, M. Nemethova, T. Pokrant, S. Brühmann, J. Linkner, L. Blanchoin, M.K. Sixt, K. Rottner, J. Faix, ELife 9 (2020).
LibreCat: https://research-explorer.ista.ac.at/record/7909
DOI: 10.7554/eLife.55351
WoS: 000537208000001

The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity
E. Salzer, S. Zoghi, M.G. Kiss, F. Kage, C. Rashkova, S. Stahnke, M. Haimel, R. Platzer, M. Caldera, R.C. Ardy, B. Hoeger, J. Block, D. Medgyesi, C. Sin, S. Shahkarami, R. Kain, V. Ziaee, P. Hammerl, C. Bock, J. Menche, L. Dupré, J.B. Huppa, M.K. Sixt, A. Lomakin, K. Rottner, C.J. Binder, T.E.B. Stradal, N. Rezaei, K. Boztug, Science Immunology 5 (2020).
LibreCat: https://research-explorer.ista.ac.at/record/8132
DOI: 10.1126/sciimmunol.abc3979
WoS: 000546994600004
PMID: 32646852

Vascular surveillance by haptotactic blood platelets in inflammation and infection
L. Nicolai, K. Schiefelbein, S. Lipsky, A. Leunig, M. Hoffknecht, K. Pekayvaz, B. Raude, C. Marx, A. Ehrlich, J. Pircher, Z. Zhang, I. Saleh, A.-K. Marel, A. Löf, T. Petzold, M. Lorenz, K. Stark, R. Pick, G. Rosenberger, L. Weckbach, B. Uhl, S. Xia, C.A. Reichel, B. Walzog, C. Schulz, V. Zheden, M. Bender, R. Li, S. Massberg, F.R. Gärtner, Nature Communications 11 (2020).
LibreCat: https://research-explorer.ista.ac.at/record/8787
DOI: 10.1038/s41467-020-19515-0
WoS: 000594648000014
PMID: 33188196

Phytohormone cytokinin guides microtubule dynamics during cell progression from proliferative to differentiated stage
J.C. Montesinos López, A. Abuzeineh, A. Kopf, A. Juanes Garcia, K. Ötvös, J. Petrásek, M.K. Sixt, E. Benková, The Embo Journal 39 (2020).
LibreCat: https://research-explorer.ista.ac.at/record/8142
DOI: 10.15252/embj.2019104238
WoS: 000548311800001
PMID: 32667089

Cellular locomotion using environmental topography
A. Reversat, F.R. Gärtner, J. Merrin, J.A. Stopp, S. Tasciyan, J.L. Aguilera Servin, I. de Vries, R. Hauschild, M. Hons, M. Piel, A. Callan-Jones, R. Voituriez, M.K. Sixt, Nature 582 (2020) 582–585.
LibreCat: https://research-explorer.ista.ac.at/record/7885
DOI: 10.1038/s41586-020-2283-z
WoS: 000532688300008

Zena Werb (1945-2020): Cell biology in context
M.K. Sixt, A. Huttenlocher, The Journal of Cell Biology 219 (2020).
LibreCat: https://research-explorer.ista.ac.at/record/8190
DOI: 10.1083/jcb.202007029
WoS: 000573631000004

Patrolling the vascular borders: Platelets in immunity to infection and cancer
F.R. Gärtner, S. Massberg, Nature Reviews Immunology 19 (2019) 747–760.
LibreCat: https://research-explorer.ista.ac.at/record/6824
DOI: 10.1038/s41577-019-0202-z
WoS: 000499090600011
PMID: 31409920

Mechanisms of 3D cell migration
K. Yamada, M.K. Sixt, Nature Reviews Molecular Cell Biology 20 (2019) 738–752.
LibreCat: https://research-explorer.ista.ac.at/record/7009
DOI: 10.1038/s41580-019-0172-9
WoS: 000497966900007
PMID: 31582855

Platelets in host defense: Experimental and clinical insights
L. Nicolai, F.R. Gärtner, S. Massberg, Trends in Immunology 40 (2019) 922–938.
LibreCat: https://research-explorer.ista.ac.at/record/6988
DOI: 10.1016/j.it.2019.08.004
WoS: 000493292100005
PMID: 31601520

Gut homeostasis: Active migration of intestinal epithelial cells in tissue renewal
A. Kopf, M.K. Sixt, Current Biology 29 (2019) 91–93.
LibreCat: https://research-explorer.ista.ac.at/record/6979
DOI: 10.1016/j.cub.2019.08.068
WoS: 000491286200016
PMID: 31639357

Persistent and polarized global actin flow is essential for directionality during cell migration
L. Yolland, M. Burki, S. Marcotti, A. Luchici, F.N. Kenny, J.R. Davis, E. Serna-Morales, J. Müller, M.K. Sixt, A. Davidson, W. Wood, L.J. Schumacher, R.G. Endres, M. Miodownik, B.M. Stramer, Nature Cell Biology 21 (2019) 1370–1381.
LibreCat: https://research-explorer.ista.ac.at/record/7105
DOI: 10.1038/s41556-019-0411-5
WoS: 000495888300009
PMID: 31685997