An/C is an essential player in the centrosome maintenance program regulated by Polo kinase and the PCM
A. Pimenta-Marques, T. Perestrelo, P. Dos Reis Rodrigues, P. Duarte, A. Ferreira-Silva, M. Lince-Faria, M. Bettencourt-Dias, EMBO Reports 25 (2024) 102–127.
LibreCat: https://research-explorer.ista.ac.at/record/14933
DOI: 10.1038/s44319-023-00020-6

Friction forces determine cytoplasmic reorganization and shape changes of ascidian oocytes upon fertilization
S. Caballero Mancebo, R. Shinde, M. Bolger-Munro, M. Peruzzo, G. Szep, I. Steccari, D. Labrousse Arias, V. Zheden, J. Merrin, A. Callan-Jones, R. Voituriez, C.-P.J. Heisenberg, Nature Physics (2024).
LibreCat: https://research-explorer.ista.ac.at/record/14846
DOI: 10.1038/s41567-023-02302-1

Lift-out cryo-FIBSEM and cryo-ET reveal the ultrastructural landscape of extracellular matrix
B. Zens, F. Fäßler, J. Hansen, R. Hauschild, J. Datler, V.-V. Hodirnau, V. Zheden, J.H. Alanko, M.K. Sixt, F.K. Schur, Journal of Cell Biology 223 (2024).
LibreCat: https://research-explorer.ista.ac.at/record/15146
DOI: 10.1083/jcb.202309125
PMID: 38506714

Integrin ;21–mediated mast cell immune-surveillance of blood vessel content
K. Link, L. Muhandes, A. Polikarpova, T. Lämmermann, M.K. Sixt, R. Fässler, A. Roers, Journal of Allergy and Clinical Immunology (n.d.).
LibreCat: https://research-explorer.ista.ac.at/record/15408
DOI: 10.1016/j.jaci.2024.03.022

En-Face Imaging of T Cell-Dendritic Cell Immunological Synapses
A.F. Leithner, J. Merrin, M.K. Sixt, in:, C. Baldari, M. Dustin (Eds.), The Immune Synapse, Springer Nature, New York, NY, 2023, pp. 137–147.
LibreCat: https://research-explorer.ista.ac.at/record/13052
DOI: 10.1007/978-1-0716-3135-5_9
PMID: 37106180

The excitable nature of polymerizing actin and the Belousov-Zhabotinsky reaction
M. Riedl, M.K. Sixt, Frontiers in Cell and Developmental Biology 11 (2023).
LibreCat: https://research-explorer.ista.ac.at/record/14555
DOI: 10.3389/fcell.2023.1287420

Synchronization in collectively moving active matter
M. Riedl, Synchronization in Collectively Moving Active Matter, Institute of Science and Technology Austria, 2023.
LibreCat: https://research-explorer.ista.ac.at/record/14530
DOI: 10.15479/14530

Synchronization in collectively moving inanimate and living active matter
M. Riedl, I.D. Mayer, J. Merrin, M.K. Sixt, B. Hof, Nature Communications 14 (2023).
LibreCat: https://research-explorer.ista.ac.at/record/14361
DOI: 10.1038/s41467-023-41432-1
WoS: 001087583700030
PMID: 37704595

Sensing their plasma membrane curvature allows migrating cells to circumvent obstacles
E. Sitarska, S.D. Almeida, M.S. Beckwith, J.A. Stopp, J. Czuchnowski, M. Siggel, R. Roessner, A. Tschanz, C. Ejsing, Y. Schwab, J. Kosinski, M.K. Sixt, A. Kreshuk, A. Erzberger, A. Diz-Muñoz, Nature Communications 14 (2023).
LibreCat: https://research-explorer.ista.ac.at/record/14360
DOI: 10.1038/s41467-023-41173-1
WoS: 001087583700008
PMID: 37704612

CC acts as both a sensor and a sink for CCL19 to coordinate collective leukocyte migration
J.H. Alanko, M.C. Ucar, N. Canigova, J.A. Stopp, J. Schwarz, J. Merrin, E.B. Hannezo, M.K. Sixt, Science Immunology 8 (2023).
LibreCat: https://research-explorer.ista.ac.at/record/14274
DOI: 10.1126/sciimmunol.adc9584
WoS: 001062110600003
PMID: 37656776

Neutrophils on the hunt: Migratory strategies employed by neutrophils to fulfill their effector function
J.A. Stopp, Neutrophils on the Hunt: Migratory Strategies Employed by Neutrophils to Fulfill Their Effector Function, Institute of Science and Technology Austria, 2023.
LibreCat: https://research-explorer.ista.ac.at/record/14697
DOI: 10.15479/at:ista:14697

Probing Single Chaperone Substrates
F. Wruck, M. Avellaneda Sarrió, M.M. Naqvi, E.J. Koers, K. Till, L. Gross, F. Moayed, A. Roland, L.W.H.J. Heling, A. Mashaghi, S.J. Tans, in:, S. Hiller, M. Liu, L. He (Eds.), Biophysics of Molecular Chaperones, Royal Society of Chemistry, 2023, pp. 278–318.
LibreCat: https://research-explorer.ista.ac.at/record/14848
DOI: 10.1039/bk9781839165986-00278

Multitier mechanics control stromal adaptations in swelling lymph nodes
F.P. Assen, J. Abe, M. Hons, R. Hauschild, S. Shamipour, W. Kaufmann, T. Costanzo, G. Krens, M. Brown, B. Ludewig, S. Hippenmeyer, C.-P.J. Heisenberg, W. Weninger, E.B. Hannezo, S.A. Luther, J.V. Stein, M.K. Sixt, Nature Immunology 23 (2022) 1246–1255.
LibreCat: https://research-explorer.ista.ac.at/record/9794
DOI: 10.1038/s41590-022-01257-4
WoS: 000822975900002

Single platelet and megakaryocyte morpho-dynamics uncovered by multicolor reporter mouse strains in vitro and in vivo
L. Nicolai, R. Kaiser, R. Escaig, M.L. Hoffknecht, A. Anjum, A. Leunig, J. Pircher, A. Ehrlich, M. Lorenz, H. Ishikawa-Ankerhold, W.C. Aird, S. Massberg, F.R. Gärtner, Haematologica 107 (2022) 1669–1680.
LibreCat: https://research-explorer.ista.ac.at/record/11588
DOI: 10.3324/haematol.2021.278896
WoS: 000823746100018

Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to C
K. Tomasek, A.F. Leithner, I. Glatzová, M.S. Lukesch, C.C. Guet, M.K. Sixt, ELife 11 (2022).
LibreCat: https://research-explorer.ista.ac.at/record/11843
DOI: 10.7554/eLife.78995
WoS: 000838410200001

Weak catch bonds make strong networks
Y. Mulla, M. Avellaneda Sarrió, A. Roland, L. Baldauf, W. Jung, T. Kim, S.J. Tans, G.H. Koenderink, Nature Materials 21 (2022) 1019–1023.
LibreCat: https://research-explorer.ista.ac.at/record/12085
DOI: 10.1038/s41563-022-01288-0
WoS: 000844592000002
PMID: 36008604

Neutrophil cpluckingd on megakaryocytes drives platelet production and boosts cardiovascular disease
T. Petzold, Z. Zhang, I. Ballesteros, I. Saleh, A. Polzin, M. Thienel, L. Liu, Q. Ul Ain, V. Ehreiser, C. Weber, B. Kilani, P. Mertsch, J. Götschke, S. Cremer, W. Fu, M. Lorenz, H. Ishikawa-Ankerhold, E. Raatz, S. El-Nemr, A. Görlach, E. Marhuenda, K. Stark, J. Pircher, D. Stegner, C. Gieger, M. Schmidt-Supprian, F.R. Gärtner, I. Almendros, M. Kelm, C. Schulz, A. Hidalgo, S. Massberg, Immunity 55 (2022) 2285–2299.e7.
LibreCat: https://research-explorer.ista.ac.at/record/12119
DOI: 10.1016/j.immuni.2022.10.001
WoS: 000922019600003
PMID: 36272416

Principles of disease defence in organisms, superorganisms and societies
S. Cremer, M.K. Sixt, Nature Reviews Immunology 22 (2022) 713–714.
LibreCat: https://research-explorer.ista.ac.at/record/12133
DOI: 10.1038/s41577-022-00797-y
WoS: 000871836300001
PMID: 36284178

Plan your trip before you leave: The neutrophils’ search-and-run journey
J.A. Stopp, M.K. Sixt, Journal of Cell Biology 221 (2022).
LibreCat: https://research-explorer.ista.ac.at/record/12272
DOI: 10.1083/jcb.202206127
WoS: 000874717200001
PMID: 35856919

WASp triggers mechanosensitive actin patches to facilitate immune cell migration in dense tissues
F. Gaertner, P. Reis-Rodrigues, I. de Vries, M. Hons, J. Aguilera, M. Riedl, A.F. Leithner, S. Tasciyan, A. Kopf, J. Merrin, V. Zheden, W. Kaufmann, R. Hauschild, M.K. Sixt, Developmental Cell 57 (2022) 47–62.e9.
LibreCat: https://research-explorer.ista.ac.at/record/10703
DOI: 10.1016/j.devcel.2021.11.024
WoS: 000768933800005
PMID: 34919802

Role of microenvironment heterogeneity in cancer cell invasion
S. Tasciyan, Role of Microenvironment Heterogeneity in Cancer Cell Invasion, Institute of Science and Technology Austria, 2022.
LibreCat: https://research-explorer.ista.ac.at/record/12401
DOI: 10.15479/at:ista:12401

In vitro reconstitution reveals phosphoinositides as cargo-release factors and activators of the AR GAP ADA
C.F. Düllberg, A. Auer, N. Canigova, K. Loibl, M. Loose, PNAS 118 (2021).
LibreCat: https://research-explorer.ista.ac.at/record/8988
DOI: 10.1073/pnas.2010054118
WoS: 000607270100018
PMID: 33443153

Shape and function of interstitial chemokine CCL21 gradients are independent of heparan sulfates produced by lymphatic endothelium
K. Vaahtomeri, C. Moussion, R. Hauschild, M.K. Sixt, Frontiers in Immunology 12 (2021).
LibreCat: https://research-explorer.ista.ac.at/record/9259
DOI: 10.3389/fimmu.2021.630002
WoS: 000627134400001
PMID: 33717158

Engaging the front wheels to drive through fibrous terrain
F.R. Gärtner, M.K. Sixt, Developmental Cell 56 (2021) 723–725.
LibreCat: https://research-explorer.ista.ac.at/record/9294
DOI: 10.1016/j.devcel.2021.03.002
WoS: 000631681200004
PMID: 33756118

Sequential and switchable patterning for studying cellular processes under spatiotemporal control
T. Zisis, J. Schwarz, M. Balles, M. Kretschmer, M. Nemethova, R.P. Chait, R. Hauschild, J. Lange, C.C. Guet, M.K. Sixt, S. Zahler, ACS Applied Materials and Interfaces 13 (2021) 35545–35560.
LibreCat: https://research-explorer.ista.ac.at/record/9822
DOI: 10.1021/acsami.1c09850
WoS: 000683741400026
PMID: 34283577

Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion
S. Stahnke, H. Döring, C. Kusch, D.J.J. de Gorter, S. Dütting, A. Guledani, I. Pleines, M. Schnoor, M.K. Sixt, R. Geffers, M. Rohde, M. Müsken, F. Kage, A. Steffen, J. Faix, B. Nieswandt, K. Rottner, T.E.B. Stradal, Current Biology 31 (2021) 2051–2064.e8.
LibreCat: https://research-explorer.ista.ac.at/record/10834
DOI: 10.1016/j.cub.2021.02.043
WoS: 000654652200002
PMID: 33711252

Dendritic cell actin dynamics control contact duration and priming efficiency at the immunological synapse
A.F. Leithner, L. Altenburger, R. Hauschild, F.P. Assen, K. Rottner, S. TEB, A. Diz-Muñoz, J. Stein, M.K. Sixt, Journal of Cell Biology 220 (2021).
LibreCat: https://research-explorer.ista.ac.at/record/9094
DOI: 10.1083/jcb.202006081
WoS: 000626365700001
PMID: 33533935

Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development
J. Morandell, L.A. Schwarz, B. Basilico, S. Tasciyan, G.A. Dimchev, A. Nicolas, C.M. Sommer, C. Kreuzinger, C. Dotter, L. Knaus, Z. Dobler, E. Cacci, F.K. Schur, J.G. Danzl, G. Novarino, Nature Communications 12 (2021).
LibreCat: https://research-explorer.ista.ac.at/record/9429
DOI: 10.1038/s41467-021-23123-x
WoS: 000658769900010

Pathogenic Escherichia coli hijack the host immune response
K. Tomasek, Pathogenic Escherichia Coli Hijack the Host Immune Response, Institute of Science and Technology Austria, 2021.
LibreCat: https://research-explorer.ista.ac.at/record/10307
DOI: 10.15479/at:ista:10307

Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to C
K. Tomasek, A.F. Leithner, I. Glatzová, M.S. Lukesch, C.C. Guet, M.K. Sixt, BioRxiv (n.d.).
LibreCat: https://research-explorer.ista.ac.at/record/10316
DOI: 10.1101/2021.10.18.464770

Partial loss of actin nucleator actin-related protein 2/3 activity triggers blebbing in primary T lymphocytes
P. Obeidy, L.A. Ju, S.H. Oehlers, N.S. Zulkhernain, Q. Lee, J.L. Galeano Niño, R.Y.Q. Kwan, S. Tikoo, L.L. Cavanagh, P. Mrass, A.J.L. Cook, S.P. Jackson, M. Biro, B. Roediger, M.K. Sixt, W. Weninger, Immunology and Cell Biology 98 (2020) 93–113.
LibreCat: https://research-explorer.ista.ac.at/record/7234
DOI: 10.1111/imcb.12304
WoS: 000503885600001
PMID: 31698518

Modeling adhesion-independent cell migration
G. Jankowiak, D. Peurichard, A. Reversat, C. Schmeiser, M.K. Sixt, Mathematical Models and Methods in Applied Sciences 30 (2020) 513–537.
LibreCat: https://research-explorer.ista.ac.at/record/7623
DOI: 10.1142/S021820252050013X
WoS: 000525349900003
arXiv: 1903.09426

Microtubules control cellular shape and coherence in amoeboid migrating cells
A. Kopf, J. Renkawitz, R. Hauschild, I. Girkontaite, K. Tedford, J. Merrin, O. Thorn-Seshold, D. Trauner, H. Häcker, K.D. Fischer, E. Kiermaier, M.K. Sixt, The Journal of Cell Biology 219 (2020).
LibreCat: https://research-explorer.ista.ac.at/record/7875
DOI: 10.1083/jcb.201907154
WoS: 000538141100020
PMID: 32379884

T cells: Bridge-and-channel commute to the white pulp
M.K. Sixt, T. Lämmermann, Immunity 52 (2020) 721–723.
LibreCat: https://research-explorer.ista.ac.at/record/7876
DOI: 10.1016/j.immuni.2020.04.020
WoS: 000535371100002

Loss of Ena/VASP interferes with lamellipodium architecture, motility and integrin-dependent adhesion
J. Damiano-Guercio, L. Kurzawa, J. Müller, G.A. Dimchev, M. Schaks, M. Nemethova, T. Pokrant, S. Brühmann, J. Linkner, L. Blanchoin, M.K. Sixt, K. Rottner, J. Faix, ELife 9 (2020).
LibreCat: https://research-explorer.ista.ac.at/record/7909
DOI: 10.7554/eLife.55351
WoS: 000537208000001

The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity
E. Salzer, S. Zoghi, M.G. Kiss, F. Kage, C. Rashkova, S. Stahnke, M. Haimel, R. Platzer, M. Caldera, R.C. Ardy, B. Hoeger, J. Block, D. Medgyesi, C. Sin, S. Shahkarami, R. Kain, V. Ziaee, P. Hammerl, C. Bock, J. Menche, L. Dupré, J.B. Huppa, M.K. Sixt, A. Lomakin, K. Rottner, C.J. Binder, T.E.B. Stradal, N. Rezaei, K. Boztug, Science Immunology 5 (2020).
LibreCat: https://research-explorer.ista.ac.at/record/8132
DOI: 10.1126/sciimmunol.abc3979
WoS: 000546994600004
PMID: 32646852

Vascular surveillance by haptotactic blood platelets in inflammation and infection
L. Nicolai, K. Schiefelbein, S. Lipsky, A. Leunig, M. Hoffknecht, K. Pekayvaz, B. Raude, C. Marx, A. Ehrlich, J. Pircher, Z. Zhang, I. Saleh, A.-K. Marel, A. Löf, T. Petzold, M. Lorenz, K. Stark, R. Pick, G. Rosenberger, L. Weckbach, B. Uhl, S. Xia, C.A. Reichel, B. Walzog, C. Schulz, V. Zheden, M. Bender, R. Li, S. Massberg, F.R. Gärtner, Nature Communications 11 (2020).
LibreCat: https://research-explorer.ista.ac.at/record/8787
DOI: 10.1038/s41467-020-19515-0
WoS: 000594648000014
PMID: 33188196

Phytohormone cytokinin guides microtubule dynamics during cell progression from proliferative to differentiated stage
J.C. Montesinos López, A. Abuzeineh, A. Kopf, A. Juanes Garcia, K. Ötvös, J. Petrásek, M.K. Sixt, E. Benková, The Embo Journal 39 (2020).
LibreCat: https://research-explorer.ista.ac.at/record/8142
DOI: 10.15252/embj.2019104238
WoS: 000548311800001
PMID: 32667089

Cellular locomotion using environmental topography
A. Reversat, F.R. Gärtner, J. Merrin, J.A. Stopp, S. Tasciyan, J.L. Aguilera Servin, I. de Vries, R. Hauschild, M. Hons, M. Piel, A. Callan-Jones, R. Voituriez, M.K. Sixt, Nature 582 (2020) 582–585.
LibreCat: https://research-explorer.ista.ac.at/record/7885
DOI: 10.1038/s41586-020-2283-z
WoS: 000532688300008

Zena Werb (1945-2020): Cell biology in context
M.K. Sixt, A. Huttenlocher, The Journal of Cell Biology 219 (2020).
LibreCat: https://research-explorer.ista.ac.at/record/8190
DOI: 10.1083/jcb.202007029
WoS: 000573631000004

Patrolling the vascular borders: Platelets in immunity to infection and cancer
F.R. Gärtner, S. Massberg, Nature Reviews Immunology 19 (2019) 747–760.
LibreCat: https://research-explorer.ista.ac.at/record/6824
DOI: 10.1038/s41577-019-0202-z
WoS: 000499090600011
PMID: 31409920

Mechanisms of 3D cell migration
K. Yamada, M.K. Sixt, Nature Reviews Molecular Cell Biology 20 (2019) 738–752.
LibreCat: https://research-explorer.ista.ac.at/record/7009
DOI: 10.1038/s41580-019-0172-9
WoS: 000497966900007
PMID: 31582855

Platelets in host defense: Experimental and clinical insights
L. Nicolai, F.R. Gärtner, S. Massberg, Trends in Immunology 40 (2019) 922–938.
LibreCat: https://research-explorer.ista.ac.at/record/6988
DOI: 10.1016/j.it.2019.08.004
WoS: 000493292100005
PMID: 31601520

Gut homeostasis: Active migration of intestinal epithelial cells in tissue renewal
A. Kopf, M.K. Sixt, Current Biology 29 (2019) 91–93.
LibreCat: https://research-explorer.ista.ac.at/record/6979
DOI: 10.1016/j.cub.2019.08.068
WoS: 000491286200016
PMID: 31639357

Persistent and polarized global actin flow is essential for directionality during cell migration
L. Yolland, M. Burki, S. Marcotti, A. Luchici, F.N. Kenny, J.R. Davis, E. Serna-Morales, J. Müller, M.K. Sixt, A. Davidson, W. Wood, L.J. Schumacher, R.G. Endres, M. Miodownik, B.M. Stramer, Nature Cell Biology 21 (2019) 1370–1381.
LibreCat: https://research-explorer.ista.ac.at/record/7105
DOI: 10.1038/s41556-019-0411-5
WoS: 000495888300009
PMID: 31685997

GG and RA promote activity-dependent ;21-integrin recycling
P. Sahgal, J.H. Alanko, J. Icha, I. Paatero, H. Hamidi, A. Arjonen, M. Pietilä, A. Rokka, J. Ivaska, Journal of Cell Science 132 (2019).
LibreCat: https://research-explorer.ista.ac.at/record/7420
DOI: 10.1242/jcs.233387
WoS: 000473327900017
PMID: 31076515

Transient localization of the Ar/3 complex initiates neuronal dendrite branching in vivo
T. Stürner, A. Tatarnikova, J. Müller, B. Schaffran, H. Cuntz, Y. Zhang, M. Nemethova, S. Bogdan, V. Small, G. Tavosanis, Development 146 (2019).
LibreCat: https://research-explorer.ista.ac.at/record/7404
DOI: 10.1242/dev.171397
WoS: 000464583200006
PMID: 30910826

Lymph node mechanics: Deciphering the interplay between stroma contractility, morphology and lymphocyte trafficking
F.P. Assen, Lymph Node Mechanics: Deciphering the Interplay between Stroma Contractility, Morphology and Lymphocyte Trafficking, Institute of Science and Technology Austria, 2019.
LibreCat: https://research-explorer.ista.ac.at/record/6947
DOI: 10.15479/AT:ISTA:6947

The implication of cytoskeletal dynamics on leukocyte migration
A. Kopf, The Implication of Cytoskeletal Dynamics on Leukocyte Migration, Institute of Science and Technology Austria, 2019.
LibreCat: https://research-explorer.ista.ac.at/record/6891
DOI: 10.15479/AT:ISTA:6891

Nuclear positioning facilitates amoeboid migration along the path of least resistance
J. Renkawitz, A. Kopf, J.A. Stopp, I. de Vries, M.K. Driscoll, J. Merrin, R. Hauschild, E.S. Welf, G. Danuser, R. Fiolka, M.K. Sixt, Nature 568 (2019) 546–550.
LibreCat: https://research-explorer.ista.ac.at/record/6328
DOI: 10.1038/s41586-019-1087-5
WoS: 000465594200050
PMID: 30944468

The neural crest pitches in to remove apoptotic debris
A. Kopf, M.K. Sixt, Cell 179 (2019) 51–53.
LibreCat: https://research-explorer.ista.ac.at/record/6877
DOI: 10.1016/j.cell.2019.08.047
WoS: 000486618500011
PMID: 31539498

Platelet migration and bacterial trapping assay under flow
S. Fan, M. Lorenz, S. Massberg, F.R. Gärtner, Bio-Protocol 8 (2018).
LibreCat: https://research-explorer.ista.ac.at/record/6354
DOI: 10.21769/bioprotoc.3018

A fat lot of good for wound healing
A.M. Casano, M.K. Sixt, Developmental Cell 44 (2018) 405–406.
LibreCat: https://research-explorer.ista.ac.at/record/318
DOI: 10.1016/j.devcel.2018.02.009
WoS: 000426150700002
PMID: 29486189

Drosophila TNF modulates tissue tension in the embryo to facilitate macrophage invasive migration
A. Ratheesh, J. Bicher, M. Smutny, J. Veselá, E. Papusheva, G. Krens, W. Kaufmann, A. György, A.M. Casano, D.E. Siekhaus, Developmental Cell 45 (2018) 331–346.
LibreCat: https://research-explorer.ista.ac.at/record/308
DOI: 10.1016/j.devcel.2018.04.002
WoS: 000432461400009
PMID: 29738712

Fast and efficient genetic engineering of hematopoietic precursor cells for the study of dendritic cell migration
A.F. Leithner, J. Renkawitz, I. de Vries, R. Hauschild, H. Haecker, M.K. Sixt, European Journal of Immunology 48 (2018) 1074–1077.
LibreCat: https://research-explorer.ista.ac.at/record/437
DOI: 10.1002/eji.201747358
WoS: 000434963700016

IgM's exit route
A. Reversat, M.K. Sixt, Journal of Experimental Medicine 215 (2018) 2959–2961.
LibreCat: https://research-explorer.ista.ac.at/record/5672
DOI: 10.1084/jem.20181934
WoS: 000451920600002

Lymphatic exosomes promote dendritic cell migration along guidance cues
M. Brown, L. Johnson, D. Leone, P. Májek, K. Vaahtomeri, D. Senfter, N. Bukosza, H. Schachner, G. Asfour, B. Langer, R. Hauschild, K. Parapatics, Y. Hong, K. Bennett, R. Kain, M. Detmar, M.K. Sixt, D. Jackson, D. Kerjaschki, Journal of Cell Biology 217 (2018) 2205–2221.
LibreCat: https://research-explorer.ista.ac.at/record/275
DOI: 10.1083/jcb.201612051
WoS: 000438077800026
PMID: 29650776

Mechanistic description of spatial processes using integrative modelling of noise-corrupted imaging data
S. Hross, F.J. Theis, M.K. Sixt, J. Hasenauer, Journal of the Royal Society Interface 15 (2018).
LibreCat: https://research-explorer.ista.ac.at/record/5858
DOI: 10.1098/rsif.2018.0600
WoS: 000456783800011

Micro-engineered cpillar forestsd to study cell migration in complex but controlled 3D environments
J. Renkawitz, A. Reversat, A.F. Leithner, J. Merrin, M.K. Sixt, in:, Methods in Cell Biology, Academic Press, 2018, pp. 79–91.
LibreCat: https://research-explorer.ista.ac.at/record/153
DOI: 10.1016/bs.mcb.2018.07.004
WoS: 000452412300006
PMID: 30165964

Nano-scale microfluidics to study 3D chemotaxis at the single cell level
C. Frick, P. Dettinger, J. Renkawitz, A. Jauch, C. Berger, M. Recher, T. Schroeder, M. Mehling, PLoS One 13 (2018).
LibreCat: https://research-explorer.ista.ac.at/record/276
DOI: 10.1371/journal.pone.0198330
WoS: 000434384900031

The cell sets the tone
J.H. Alanko, M.K. Sixt, ELife 7 (2018).
LibreCat: https://research-explorer.ista.ac.at/record/5861
DOI: 10.7554/eLife.37888
WoS: 000434375000001

Optical functionalization of human class A orphan G-protein-coupled receptors
M. Morri, I. Sanchez-Romero, A.-M. Tichy, S. Kainrath, E.J. Gerrard, P. Hirschfeld, J. Schwarz, H.L. Janovjak, Nature Communications 9 (2018).
LibreCat: https://research-explorer.ista.ac.at/record/5984
DOI: 10.1038/s41467-018-04342-1
WoS: 000432280000006

On the relation between filament density, force generation, and protrusion rate in mesenchymal cell motility
S. Dolati, F. Kage, J. Mueller, M. Müsken, M. Kirchner, G. Dittmar, M.K. Sixt, K. Rottner, M. Falcke, Molecular Biology of the Cell 29 (2018) 2674–2686.
LibreCat: https://research-explorer.ista.ac.at/record/5992
DOI: 10.1091/mbc.e18-02-0082
WoS: 000455641000011
PMID: 30156465

The Rho regulator Myosin IXb enables nonlymphoid tissue seeding of protective C+T cells
F. Moalli, X. Ficht, P. Germann, M. Vladymyrov, B. Stolp, I. de Vries, R. Lyck, J. Balmer, A. Fiocchi, M. Kreutzfeldt, D. Merkler, M. Iannacone, A. Ariga, M.H. Stoffel, J. Sharpe, M. Bähler, M.K. Sixt, A. Diz-Muñoz, J.V. Stein, The Journal of Experimental Medicine 2015 (2018) 1869–1890.
LibreCat: https://research-explorer.ista.ac.at/record/6497
DOI: 10.1084/jem.20170896
WoS: 000440822900011

Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice
M. Brown, F.P. Assen, A.F. Leithner, J. Abe, H. Schachner, G. Asfour, Z. Bagó Horváth, J. Stein, P. Uhrin, M.K. Sixt, D. Kerjaschki, Science 359 (2018) 1408–1411.
LibreCat: https://research-explorer.ista.ac.at/record/402
DOI: 10.1126/science.aal3662
WoS: 000428043600047
PMID: 29567714

Branched actin networks in dendritic cell biology
A.F. Leithner, Branched Actin Networks in Dendritic Cell Biology, Institute of Science and Technology Austria, 2018.
LibreCat: https://research-explorer.ista.ac.at/record/323
DOI: 10.15479/AT:ISTA:th_998

Chemokines and integrins independently tune actin flow and substrate friction during intranodal migration of T cells
M. Hons, A. Kopf, R. Hauschild, A.F. Leithner, F.R. Gärtner, J. Abe, J. Renkawitz, J. Stein, M.K. Sixt, Nature Immunology 19 (2018) 606–616.
LibreCat: https://research-explorer.ista.ac.at/record/15
DOI: 10.1038/s41590-018-0109-z
WoS: 000433041500026
PMID: 29777221

Cytokinesis in vertebrate cells initiates by contraction of an equatorial actomyosin network composed of randomly oriented filaments
F. Spira, S. Cuylen Haering, S. Mehta, M. Samwer, A. Reversat, A. Verma, R. Oldenbourg, M.K. Sixt, D. Gerlich, ELife 6 (2017).
LibreCat: https://research-explorer.ista.ac.at/record/569
DOI: 10.7554/eLife.30867

Migrating platelets are mechano scavengers that collect and bundle bacteria
F.R. Gärtner, Z. Ahmad, G. Rosenberger, S. Fan, L. Nicolai, B. Busch, G. Yavuz, M. Luckner, H. Ishikawa Ankerhold, R. Hennel, A. Benechet, M. Lorenz, S. Chandraratne, I. Schubert, S. Helmer, B. Striednig, K. Stark, M. Janko, R. Böttcher, A. Verschoor, C. Leon, C. Gachet, T. Gudermann, M. Mederos Y Schnitzler, Z. Pincus, M. Iannacone, R. Haas, G. Wanner, K. Lauber, M.K. Sixt, S. Massberg, Cell Press 171 (2017) 1368–1382.
LibreCat: https://research-explorer.ista.ac.at/record/571
DOI: 10.1016/j.cell.2017.11.001

FMNL formins boost lamellipodial force generation
F. Kage, M. Winterhoff, V. Dimchev, J. Müller, T. Thalheim, A. Freise, S. Brühmann, J. Kollasser, J. Block, G.A. Dimchev, M. Geyer, H. Schnittler, C. Brakebusch, T. Stradal, M. Carlier, M.K. Sixt, J. Käs, J. Faix, K. Rottner, Nature Communications 8 (2017).
LibreCat: https://research-explorer.ista.ac.at/record/659
DOI: 10.1038/ncomms14832

Multiple roles of filopodial dynamics in particle capture and phagocytosis and phenotypes of Cd and Myo10 deletion
M. Horsthemke, A. Bachg, K. Groll, S. Moyzio, B. Müther, S. Hemkemeyer, R. Wedlich Söldner, M.K. Sixt, S. Tacke, M. Bähler, P. Hanley, Journal of Biological Chemistry 292 (2017) 7258–7273.
LibreCat: https://research-explorer.ista.ac.at/record/668
DOI: 10.1074/jbc.M116.766923

Locally triggered release of the chemokine CCL21 promotes dendritic cell transmigration across lymphatic endothelia
K. Vaahtomeri, M. Brown, R. Hauschild, I. de Vries, A.F. Leithner, M. Mehling, W. Kaufmann, M.K. Sixt, Cell Reports 19 (2017) 902–909.
LibreCat: https://research-explorer.ista.ac.at/record/672
DOI: 10.1016/j.celrep.2017.04.027

Dendritic cells interpret haptotactic chemokine gradients in a manner governed by signal to noise ratio and dependent on GRK6
J. Schwarz, V. Bierbaum, K. Vaahtomeri, R. Hauschild, M. Brown, I. de Vries, A.F. Leithner, A. Reversat, J. Merrin, T. Tarrant, M.T. Bollenbach, M.K. Sixt, Current Biology 27 (2017) 1314–1325.
LibreCat: https://research-explorer.ista.ac.at/record/674
DOI: 10.1016/j.cub.2017.04.004

The INO80 complex removes A.Z to promote presynaptic filament formation during homologous recombination
C. Lademann, J. Renkawitz, B. Pfander, S. Jentsch, Cell Reports 19 (2017) 1294–1303.
LibreCat: https://research-explorer.ista.ac.at/record/677
DOI: 10.1016/j.celrep.2017.04.051

A dual phenotype of MDA MB 468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity
A. Veß, U. Blache, L. Leitner, A. Kurz, A. Ehrenpfordt, M.K. Sixt, G. Posern, Journal of Cell Science 130 (2017) 2172–2184.
LibreCat: https://research-explorer.ista.ac.at/record/694
DOI: 10.1242/jcs.200899
PMID: 28515231

Cell migration: Making the waves
J. Müller, M.K. Sixt, Current Biology 27 (2017) –.
LibreCat: https://research-explorer.ista.ac.at/record/1161
DOI: 10.1016/j.cub.2016.11.035
WoS: 000391902500010

Load adaptation of lamellipodial actin networks
J. Mueller, G. Szep, M. Nemethova, I. de Vries, A. Lieber, C. Winkler, K. Kruse, J. Small, C. Schmeiser, K. Keren, R. Hauschild, M.K. Sixt, Cell 171 (2017) 188–200.
LibreCat: https://research-explorer.ista.ac.at/record/727
DOI: 10.1016/j.cell.2017.07.051
WoS: 000411331800020

The dynamic cytokine niche
F.P. Assen, M.K. Sixt, Immunity 46 (2017) 519–520.
LibreCat: https://research-explorer.ista.ac.at/record/664
DOI: 10.1016/j.immuni.2017.04.006

The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection
F. Ebner, V. Sedlyarov, S. Tasciyan, M. Ivin, F. Kratochvill, N. Gratz, L. Kenner, A. Villunger, M.K. Sixt, P. Kovarik, The Journal of Clinical Investigation 127 (2017) 2051–2065.
LibreCat: https://research-explorer.ista.ac.at/record/679
DOI: 10.1172/JCI80631
PMID: 28504646

RASGR deficiency causes immunodeficiency with impaired cytoskeletal dynamics
E. Salzer, D. Ça7daf, M. Hons, E. Mace, W. Garncarz, O. Petronczki, R. Platzer, L. Pfajfer, I. Bilic, S. Ban, K. Willmann, M. Mukherjee, V. Supper, H. Hsu, P. Banerjee, P. Sinha, F. Mcclanahan, G. Zlabinger, W. Pickl, J. Gribben, H. Stockinger, K. Bennett, J. Huppa, L. Dupré, Ö. Sanal, U. Jäger, M.K. Sixt, I. Tezcan, J. Orange, K. Boztug, Nature Immunology 17 (2016) 1352–1360.
LibreCat: https://research-explorer.ista.ac.at/record/1137
DOI: 10.1038/ni.3575
PMID: 27776107

Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions
R. Martins, J. Maier, A. Gorki, K. Huber, O. Sharif, P. Starkl, S. Saluzzo, F. Quattrone, R. Gawish, K. Lakovits, M. Aichinger, B. Radic Sarikas, C. Lardeau, A. Hladik, A. Korosec, M. Brown, K. Vaahtomeri, M. Duggan, D. Kerjaschki, H. Esterbauer, J. Colinge, S. Eisenbarth, T. Decker, K. Bennett, S. Kubicek, M.K. Sixt, G. Superti Furga, S. Knapp, Nature Immunology 17 (2016) 1361–1372.
LibreCat: https://research-explorer.ista.ac.at/record/1142
DOI: 10.1038/ni.3590

A Radical Break Restraining Neutrophil Migration
J. Renkawitz, M.K. Sixt, Developmental Cell 38 (2016) 448–450.
LibreCat: https://research-explorer.ista.ac.at/record/1150
DOI: 10.1016/j.devcel.2016.08.017

A microfluidic device for measuring cell migration towards substrate bound and soluble chemokine gradients
J. Schwarz, V. Bierbaum, J. Merrin, T. Frank, R. Hauschild, M.T. Bollenbach, S. Tay, M.K. Sixt, M. Mehling, Scientific Reports 6 (2016).
LibreCat: https://research-explorer.ista.ac.at/record/1154
DOI: 10.1038/srep36440

Formin’ a nuclear protection
J. Renkawitz, M.K. Sixt, Cell 167 (2016) 1448–1449.
LibreCat: https://research-explorer.ista.ac.at/record/1201
DOI: 10.1016/j.cell.2016.11.024

Efficient T-cell priming and activation requires signaling through prostaglandin  (EP) receptors
V. Sreeramkumar, M. Hons, C. Punzón, J. Stein, D. Sancho, M. Fresno Forcelledo, N. Cuesta, Immunology and Cell Biology 94 (2016) 39–51.
LibreCat: https://research-explorer.ista.ac.at/record/1217
DOI: 10.1038/icb.2015.62

Focal adhesion-independent cell migration
E. Paluch, I. Aspalter, M.K. Sixt, Annual Review of Cell and Developmental Biology 32 (2016) 469–490.
LibreCat: https://research-explorer.ista.ac.at/record/1285
DOI: 10.1146/annurev-cellbio-111315-125341

Intralymphatic CCL21 promotes tissue egress of dendritic cells through afferent lymphatic vessels
E. Russo, A. Teijeira, K. Vaahtomeri, A. Willrodt, J. Bloch, M. Nitschké, L. Santambrogio, D. Kerjaschki, M.K. Sixt, C. Halin, Cell Reports 14 (2016) 1723–1734.
LibreCat: https://research-explorer.ista.ac.at/record/1490
DOI: 10.1016/j.celrep.2016.01.048

Polysialylation controls dendritic cell trafficking by regulating chemokine recognition
E. Kiermaier, C. Moussion, C. Veldkamp, R. Gerardy  Schahn, I. de Vries, L. Williams, G. Chaffee, A. Phillips, F. Freiberger, R. Imre, D. Taleski, R. Payne, A. Braun, R. Förster, K. Mechtler, M. Mühlenhoff, B. Volkman, M.K. Sixt, Science 351 (2016) 186–190.
LibreCat: https://research-explorer.ista.ac.at/record/1599
DOI: 10.1126/science.aad0512
PMID: 26657283

Quantitative analysis of dendritic cell haptotaxis
J. Schwarz, M.K. Sixt, Methods in Enzymology 570 (2016) 567–581.
LibreCat: https://research-explorer.ista.ac.at/record/1597
DOI: 10.1016/bs.mie.2015.11.004
PMID: 26921962

Quantitative analysis of haptotactic cell migration
J. Schwarz, Quantitative Analysis of Haptotactic Cell Migration, Institute of Science and Technology Austria, 2016.
LibreCat: https://research-explorer.ista.ac.at/record/1129

Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes
A.F. Leithner, A. Eichner, J. Müller, A. Reversat, M. Brown, J. Schwarz, J. Merrin, D. De Gorter, F.K. Schur, J. Bayerl, I. de Vries, S. Wieser, R. Hauschild, F. Lai, M. Moser, D. Kerjaschki, K. Rottner, V. Small, T. Stradal, M.K. Sixt, Nature Cell Biology 18 (2016) 1253–1259.
LibreCat: https://research-explorer.ista.ac.at/record/1321
DOI: 10.1038/ncb3426

Impact of the cell division cycle on gene circuits
V. Bierbaum, S. Klumpp, Physical Biology 12 (2015).
LibreCat: https://research-explorer.ista.ac.at/record/1530
DOI: 10.1088/1478-3975/12/6/066003

Actin flows mediate a universal coupling between cell speed and cell persistence
P. Maiuri, J. Rupprecht, S. Wieser, V. Ruprecht, O. Bénichou, N. Carpi, M. Coppey, S. De Beco, N. Gov, C.-P.J. Heisenberg, C. Lage Crespo, F. Lautenschlaeger, M. Le Berre, A. Lennon Duménil, M. Raab, H. Thiam, M. Piel, M.K. Sixt, R. Voituriez, Cell 161 (2015) 374–386.
LibreCat: https://research-explorer.ista.ac.at/record/1553
DOI: 10.1016/j.cell.2015.01.056

A novel Cre recombinase reporter mouse strain facilitates selective and efficient infection of primary immune cells with adenoviral vectors
K. Heger, M. Kober, D. Rieß, C. Drees, I. de Vries, A. Bertossi, A. Roers, M.K. Sixt, M. Schmidt Supprian, European Journal of Immunology 45 (2015) 1614–1620.
LibreCat: https://research-explorer.ista.ac.at/record/1561
DOI: 10.1002/eji.201545457

The lymph node filter revealed
M. Hons, M.K. Sixt, Nature Immunology 16 (2015) 338–340.
LibreCat: https://research-explorer.ista.ac.at/record/1560
DOI: 10.1038/ni.3126

Cell migration and antigen capture are antagonistic processes coupled by myosin II in dendritic cells
M. Chabaud, M. Heuzé, M. Bretou, P. Vargas, P. Maiuri, P. Solanes, M. Maurin, E. Terriac, M. Le Berre, D. Lankar, T. Piolot, R. Adelstein, Y. Zhang, M.K. Sixt, J. Jacobelli, O. Bénichou, R. Voituriez, M. Piel, A. Lennon Duménil, Nature Communications 6 (2015).
LibreCat: https://research-explorer.ista.ac.at/record/1575
DOI: 10.1038/ncomms8526

Editorial overview: Cell adhesion and migration
M.K. Sixt, E. Raz, Current Opinion in Cell Biology 36 (2015) 4–6.
LibreCat: https://research-explorer.ista.ac.at/record/1676
DOI: 10.1016/j.ceb.2015.09.004

Navigating in tissue mazes: Chemoattractant interpretation in complex environments
M. Sarris, M.K. Sixt, Current Opinion in Cell Biology 36 (2015) 93–102.
LibreCat: https://research-explorer.ista.ac.at/record/1687
DOI: 10.1016/j.ceb.2015.08.001

Fragmented communication between immune cells: Neutrophils blaze a trail with migratory cues for T cells to follow to sites of infection
E. Kiermaier, M.K. Sixt, Science 349 (2015) 1055–1056.
LibreCat: https://research-explorer.ista.ac.at/record/1686
DOI: 10.1126/science.aad0867

The serotonin receptor 5-HR regulates the morphology and migratory properties of dendritic cells
K. Holst, D. Guseva, S. Schindler, M.K. Sixt, A. Braun, H. Chopra, O. Pabst, E. Ponimaskin, Journal of Cell Science 128 (2015) 2866–2880.
LibreCat: https://research-explorer.ista.ac.at/record/477
DOI: 10.1242/jcs.167999